Journal article Open Access

REVIEW OF NOVEL IN SITU GEL FOR OCULAR DRUG DELIVERY

Dr. Bharat .V. Jain, Drx. Kajal Vipin Jain*, Dr. Sandip. R. Pawar, Mr. Tanveer.Y. Shaikhb


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{
  "publisher": "Zenodo", 
  "DOI": "10.5281/zenodo.6821620", 
  "author": [
    {
      "family": "Dr. Bharat .V. Jain, Drx. Kajal Vipin Jain*, Dr. Sandip. R. Pawar,  Mr. Tanveer.Y. Shaikhb"
    }
  ], 
  "issued": {
    "date-parts": [
      [
        2022, 
        7, 
        12
      ]
    ]
  }, 
  "abstract": "<p><em>The traditional dosage form has many limitations due to factors such as naso-lacrimal drainage &amp; shorter contact time. Ophthalmic in-situ gelling system composed of environmentally sensitive polymers that will be structurally changed in response to small changes in specific condition. Environmental pH, temperature, &amp; ionic strength, Response to environmental changes, the in- situ are liquids when installation into the eyes and then undergo rapidly gelation into the Cul- de-sac of the eye to form visco-elastic gel. This tends to increase ocular residence time and decreases Precorneal drug loss as a result. The goal of this study is to prepare and evaluate In- situ Gel for ocular drug delivery by using mucoadhesive polymers to increase ocular residence time and minimize Precorneal drugs loss of given formulation.</em></p>\n\n<p><strong>Keywords: </strong><em>Ocular Drug Delivery, In-situ Gelling System, Conjunctivitis.</em></p>", 
  "title": "REVIEW OF NOVEL IN SITU GEL FOR OCULAR DRUG DELIVERY", 
  "type": "article-journal", 
  "id": "6821620"
}
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