NOVEL ANALYTICAL TECHNIQUES USED IN METHOD DEVELOPMENT AND VALIDATION OF PHARMACEUTICALS

The major goal of this review is to explain the novel analytical techniques used in method development and validation of various medicines because they are vitally important for the drug's consistency, efficacy, and quality. LC-MS, RP-HPLC, and other innovative analytical techniques During this review, automated development in HPTLC and LC-MS-MS are discussed using appropriate drug samples in accordance with ICH Guidelines. ICH Guidelines also specify many validation characteristics such as accuracy, specificity, precision, linearity, LOD, LOQ, ruggedness, and robustness. Validation is tremendously beneficial to pharmaceutical standard control and quality assurance, as well as patient safety.

Key words:Method development, Validation, Analytical Techniques