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Published April 17, 2022 | Version v1
Journal article Open

OVERVIEW OF APPROACH TO FEVER OF UNKNOWN IN INFANT

Description

Fever of unknown origin (FUO) can be caused by many clinical conditions and remains a diagnostic challenge in clinical practice. The etiology of FUO varies markedly among different age groups, geographic areas, and seasons. A four-stage investigative protocol for FUO is widely applied in clinical practice. The aim of the review was to go through the different approaches in managing infant with fever of unknown origin, by searching the databases for all published studies up to 2021. In conclusion infant with FUO should be evaluated using the four-stage protocol. Epidemiological data, contact history, previous medical history, fever pattern, detailed physical examination, and screening tests provide adequate information to establish a diagnosis.

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