Published March 18, 2022 | Version 1.0.0
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Script to determine current amplitude in single cell recordings of dopamine neurons in cell culture

  • 1. Karolinska Institutet

Description

Simple Matlab script to determine current amplitude in single cell recordings of dopamine neurons in cell culture (IV_currents.m) as used for Supplementary Figure 6 in Alekseenko et al. (2022). The Matlab script to plot the figure is also included (boxplot_currentsFigS6.m) together with the data included in the figure (data_table_currents.mat). 

The two abf-files are example recordings to be used to test the IV_currents.m, by default it will load Day38_C11_19n07081.abf.
 

References:

Zhanna Alekseenko, José M. Dias, Andrew F. Adler, Mariya Kozhevnikova, Josina Anna van Lunteren, Sara Nolbrant, Ashwini Jeggari, Svitlana Vasylovska, Takashi Yoshitake, Jan Kehr, Marie Carlén, Andrey Alexeyenko, Malin Parmar, and Johan Ericson (2022) Robust derivation of transplantable dopamine neurons from human pluripotent stem cells by timed retinoic acid delivery. Manuscript submitted for publication

 

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