Published February 26, 2022
| Version v1
Preprint
Open
The Huanan market was the epicenter of SARS-CoV-2 emergence
Creators
- Michael Worobey1
- Joshua I. Levy2
- Lorena M. Malpica Serrano1
- Alexander Crits-Christoph3
- Jonathan E. Pekar4
- Stephen A. Goldstein5
- Angela L. Rasmussen6
- Moritz U. G. Kraemer7
- Chris Newman8
- Marion P. G. Koopmans9
- Marc A. Suchard10
- Joel O. Wertheim11
- Philippe Lemey12
- David L. Robertson13
- Robert F. Garry14
- Edward C. Holmes15
- Andrew Rambaut16
- Kristian G. Andersen2
- 1. Department of Ecology and Evolutionary Biology, University of Arizona, Tucson, AZ 85721, USA
- 2. Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA
- 3. W. Harry Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, 21205, USA
- 4. Bioinformatics and Systems Biology Graduate Program, University of California San Diego, La Jolla, CA 92093, USA
- 5. Department of Human Genetics, University of Utah School of Medicine, Salt Lake City, UT 84112, USA
- 6. Vaccine and Infectious Disease Organization, University of Saskatchewan, Saskatoon, SK S7N 5E3, Canada
- 7. Department of Zoology, University of Oxford, Oxford, UK
- 8. Wildlife Conservation Research Unit, Department of Zoology, The Recanati-Kaplan Centre, University of Oxford, Oxford, OX13 5QL, UK
- 9. Department of Viroscience, Erasmus University Medical Center, Rotterdam, Netherlands
- 10. Department of Biostatistics, Fielding School of Public Health, University of California Los Angeles, Los Angeles, CA 90095, USA
- 11. Department of Medicine, University of California San Diego, La Jolla, CA 92093, USA
- 12. Department of Microbiology, Immunology, and Transplantation, Rega Institute, KU Leuven, Leuven, Belgium
- 13. MRC-University of Glasgow Center for Virus Research, Glasgow, G61 1QH, UK
- 14. Tulane University, School of Medicine, Department of Microbiology and Immunology, New Orleans, LA, 70112 USA
- 15. Sydney Institute for Infectious Diseases, School of Life and Environmental Sciences and School of Medical Sciences, The University of Sydney, Sydney, NSW 2006, Australia
- 16. Institute of Evolutionary Biology, University of Edinburgh, King's Buildings, Edinburgh, EH9 3FL, UK
Description
Geographical clustering of the earliest known COVID-19 cases and the proximity of positive environmental samples to live-animal vendors suggest that the Huanan Seafood Wholesale Market in Wuhan was the site of origin of the COVID-19 pandemic.
Files
2020.02.26_worobey_preprint.pdf
Files
(29.2 MB)
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