Dataset Open Access

Secretin-like class B G protein-coupled receptor (GPCR) mutation data set

de Graaf, Chris


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    <subfield code="a">&lt;p&gt;Curated set of&amp;nbsp;2463 quantitative mutation data points&amp;nbsp;covering 13 secretin-like class B&amp;nbsp;G protein-coupled receptors.&lt;/p&gt;

&lt;p&gt;Annotated according to GPCRdb standards (http://gpcrdb.org/), complemented by GPCRdb Ballesteros-Weinstein numbers assigned&amp;nbsp;using GPCRdb KNIME nodes (https://github.com/3D-e-Chem/knime-gpcrdb).&lt;/p&gt;

&lt;p&gt;The data set is build from data sets published in:&lt;/p&gt;

&lt;p&gt;- Siu et al. Nature 2013,&amp;nbsp;499: 444-449. doi:10.1038/nature12393&lt;/p&gt;

&lt;p&gt;- Hollenstein, de Graaf&amp;nbsp;et al. Tr Pharmacol Sci&amp;nbsp;2014, 35: 12-22. doi: 10.1016/j.tips.2013.11.001&lt;/p&gt;

&lt;p&gt;- Yang, de Graaf et al. J Biol Chem 2016, 291: 12991-3004. doi: 10.1074/jbc.M116.721977&lt;/p&gt;</subfield>
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