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Secretin-like class B G protein-coupled receptor (GPCR) mutation data set

de Graaf, Chris


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  <dc:creator>de Graaf, Chris</dc:creator>
  <dc:date>2016-08-24</dc:date>
  <dc:description>Curated set of 2463 quantitative mutation data points covering 13 secretin-like class B G protein-coupled receptors.

Annotated according to GPCRdb standards (http://gpcrdb.org/), complemented by GPCRdb Ballesteros-Weinstein numbers assigned using GPCRdb KNIME nodes (https://github.com/3D-e-Chem/knime-gpcrdb).

The data set is build from data sets published in:

- Siu et al. Nature 2013, 499: 444-449. doi:10.1038/nature12393

- Hollenstein, de Graaf et al. Tr Pharmacol Sci 2014, 35: 12-22. doi: 10.1016/j.tips.2013.11.001

- Yang, de Graaf et al. J Biol Chem 2016, 291: 12991-3004. doi: 10.1074/jbc.M116.721977</dc:description>
  <dc:identifier>https://zenodo.org/record/60790</dc:identifier>
  <dc:identifier>10.5281/zenodo.60790</dc:identifier>
  <dc:identifier>oai:zenodo.org:60790</dc:identifier>
  <dc:relation>doi:10.1016/j.tips.2013.11.001</dc:relation>
  <dc:relation>doi:10.1074/jbc.M116.721977</dc:relation>
  <dc:relation>doi:10.1038/nature12393</dc:relation>
  <dc:rights>info:eu-repo/semantics/openAccess</dc:rights>
  <dc:rights>https://creativecommons.org/publicdomain/zero/1.0/legalcode</dc:rights>
  <dc:subject>G protein-coupled receptor (GPCR)</dc:subject>
  <dc:subject>site directed mutagenesis</dc:subject>
  <dc:subject>secretin-like receptors</dc:subject>
  <dc:subject>class B GPCR</dc:subject>
  <dc:subject>glucagon receptor (GCGR)</dc:subject>
  <dc:subject>glucagon like peptide 1 receptor (GLP-1R) </dc:subject>
  <dc:subject>growth hormone-releasing factor receptor (GHRH)</dc:subject>
  <dc:subject>gastric inhibitory polypeptide receptor (GIPR)</dc:subject>
  <dc:subject>calcitonin receptor (CALCR)</dc:subject>
  <dc:subject>calcitonin receptor-like receptor (CALRL)</dc:subject>
  <dc:subject>corticotropin releasing hormone receptor 1 (CRFR1)</dc:subject>
  <dc:subject>corticotropin releasing hormone receptor 2 (CRFR2)</dc:subject>
  <dc:subject>parathyroid hormone 1 receptor (PTH1R)</dc:subject>
  <dc:subject>parathyroid hormone 2 receptor (PTH2R)</dc:subject>
  <dc:subject>secretin receptor (SCTR)</dc:subject>
  <dc:subject>vasoactive intestinal peptide receptor 1 (VIPR1)</dc:subject>
  <dc:subject>vasoactive intestinal peptide receptor 2 (VIPR2)</dc:subject>
  <dc:title>Secretin-like class B G protein-coupled receptor (GPCR) mutation data set</dc:title>
  <dc:type>info:eu-repo/semantics/other</dc:type>
  <dc:type>dataset</dc:type>
</oai_dc:dc>
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