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Secretin-like class B G protein-coupled receptor (GPCR) mutation data set

de Graaf, Chris


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{
  "description": "<p>Curated set of&nbsp;2463 quantitative mutation data points&nbsp;covering 13 secretin-like class B&nbsp;G protein-coupled receptors.</p>\n\n<p>Annotated according to GPCRdb standards (http://gpcrdb.org/), complemented by GPCRdb Ballesteros-Weinstein numbers assigned&nbsp;using GPCRdb KNIME nodes (https://github.com/3D-e-Chem/knime-gpcrdb).</p>\n\n<p>The data set is build from data sets published in:</p>\n\n<p>- Siu et al. Nature 2013,&nbsp;499: 444-449. doi:10.1038/nature12393</p>\n\n<p>- Hollenstein, de Graaf&nbsp;et al. Tr Pharmacol Sci&nbsp;2014, 35: 12-22. doi: 10.1016/j.tips.2013.11.001</p>\n\n<p>- Yang, de Graaf et al. J Biol Chem 2016, 291: 12991-3004. doi: 10.1074/jbc.M116.721977</p>", 
  "license": "https://creativecommons.org/publicdomain/zero/1.0/legalcode", 
  "creator": [
    {
      "affiliation": "Vrije Universiteit Amsterdam", 
      "@type": "Person", 
      "name": "de Graaf, Chris"
    }
  ], 
  "url": "https://zenodo.org/record/60790", 
  "datePublished": "2016-08-24", 
  "keywords": [
    "G protein-coupled receptor (GPCR)", 
    "site directed mutagenesis", 
    "secretin-like receptors", 
    "class B GPCR", 
    "glucagon receptor (GCGR)", 
    "glucagon like peptide 1 receptor (GLP-1R) ", 
    "growth hormone-releasing factor receptor (GHRH)", 
    "gastric inhibitory polypeptide receptor (GIPR)", 
    "calcitonin receptor (CALCR)", 
    "calcitonin receptor-like receptor (CALRL)", 
    "corticotropin releasing hormone receptor 1 (CRFR1)", 
    "corticotropin releasing hormone receptor 2 (CRFR2)", 
    "parathyroid hormone 1 receptor (PTH1R)", 
    "parathyroid hormone 2 receptor (PTH2R)", 
    "secretin receptor (SCTR)", 
    "vasoactive intestinal peptide receptor 1 (VIPR1)", 
    "vasoactive intestinal peptide receptor 2 (VIPR2)"
  ], 
  "@context": "https://schema.org/", 
  "distribution": [
    {
      "contentUrl": "https://zenodo.org/api/files/8e07343b-0d5b-42b7-9948-4dfa85116134/secretin-like_class_B_GPCR_mutation_data_de_Graaf_VUA_230816.xlsx", 
      "encodingFormat": "xlsx", 
      "@type": "DataDownload"
    }
  ], 
  "identifier": "https://doi.org/10.5281/zenodo.60790", 
  "@id": "https://doi.org/10.5281/zenodo.60790", 
  "@type": "Dataset", 
  "name": "Secretin-like class B G protein-coupled receptor (GPCR) mutation data set"
}
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