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Secretin-like class B G protein-coupled receptor (GPCR) mutation data set

de Graaf, Chris


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    "description": "<p>Curated set of&nbsp;2463 quantitative mutation data points&nbsp;covering 13 secretin-like class B&nbsp;G protein-coupled receptors.</p>\n\n<p>Annotated according to GPCRdb standards (http://gpcrdb.org/), complemented by GPCRdb Ballesteros-Weinstein numbers assigned&nbsp;using GPCRdb KNIME nodes (https://github.com/3D-e-Chem/knime-gpcrdb).</p>\n\n<p>The data set is build from data sets published in:</p>\n\n<p>- Siu et al. Nature 2013,&nbsp;499: 444-449. doi:10.1038/nature12393</p>\n\n<p>- Hollenstein, de Graaf&nbsp;et al. Tr Pharmacol Sci&nbsp;2014, 35: 12-22. doi: 10.1016/j.tips.2013.11.001</p>\n\n<p>- Yang, de Graaf et al. J Biol Chem 2016, 291: 12991-3004. doi: 10.1074/jbc.M116.721977</p>", 
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    "title": "Secretin-like class B G protein-coupled receptor (GPCR) mutation data set", 
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    "keywords": [
      "G protein-coupled receptor (GPCR)", 
      "site directed mutagenesis", 
      "secretin-like receptors", 
      "class B GPCR", 
      "glucagon receptor (GCGR)", 
      "glucagon like peptide 1 receptor (GLP-1R) ", 
      "growth hormone-releasing factor receptor (GHRH)", 
      "gastric inhibitory polypeptide receptor (GIPR)", 
      "calcitonin receptor (CALCR)", 
      "calcitonin receptor-like receptor (CALRL)", 
      "corticotropin releasing hormone receptor 1 (CRFR1)", 
      "corticotropin releasing hormone receptor 2 (CRFR2)", 
      "parathyroid hormone 1 receptor (PTH1R)", 
      "parathyroid hormone 2 receptor (PTH2R)", 
      "secretin receptor (SCTR)", 
      "vasoactive intestinal peptide receptor 1 (VIPR1)", 
      "vasoactive intestinal peptide receptor 2 (VIPR2)"
    ], 
    "publication_date": "2016-08-24", 
    "creators": [
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        "affiliation": "Vrije Universiteit Amsterdam", 
        "name": "de Graaf, Chris"
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