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Secretin-like class B G protein-coupled receptor (GPCR) mutation data set

de Graaf, Chris


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  <identifier identifierType="DOI">10.5281/zenodo.60790</identifier>
  <creators>
    <creator>
      <creatorName>de Graaf, Chris</creatorName>
      <givenName>Chris</givenName>
      <familyName>de Graaf</familyName>
      <affiliation>Vrije Universiteit Amsterdam</affiliation>
    </creator>
  </creators>
  <titles>
    <title>Secretin-like class B G protein-coupled receptor (GPCR) mutation data set</title>
  </titles>
  <publisher>Zenodo</publisher>
  <publicationYear>2016</publicationYear>
  <subjects>
    <subject>G protein-coupled receptor (GPCR)</subject>
    <subject>site directed mutagenesis</subject>
    <subject>secretin-like receptors</subject>
    <subject>class B GPCR</subject>
    <subject>glucagon receptor (GCGR)</subject>
    <subject>glucagon like peptide 1 receptor (GLP-1R) </subject>
    <subject>growth hormone-releasing factor receptor (GHRH)</subject>
    <subject>gastric inhibitory polypeptide receptor (GIPR)</subject>
    <subject>calcitonin receptor (CALCR)</subject>
    <subject>calcitonin receptor-like receptor (CALRL)</subject>
    <subject>corticotropin releasing hormone receptor 1 (CRFR1)</subject>
    <subject>corticotropin releasing hormone receptor 2 (CRFR2)</subject>
    <subject>parathyroid hormone 1 receptor (PTH1R)</subject>
    <subject>parathyroid hormone 2 receptor (PTH2R)</subject>
    <subject>secretin receptor (SCTR)</subject>
    <subject>vasoactive intestinal peptide receptor 1 (VIPR1)</subject>
    <subject>vasoactive intestinal peptide receptor 2 (VIPR2)</subject>
  </subjects>
  <dates>
    <date dateType="Issued">2016-08-24</date>
  </dates>
  <resourceType resourceTypeGeneral="Dataset"/>
  <alternateIdentifiers>
    <alternateIdentifier alternateIdentifierType="url">https://zenodo.org/record/60790</alternateIdentifier>
  </alternateIdentifiers>
  <relatedIdentifiers>
    <relatedIdentifier relatedIdentifierType="DOI" relationType="IsSupplementTo">10.1016/j.tips.2013.11.001</relatedIdentifier>
    <relatedIdentifier relatedIdentifierType="DOI" relationType="IsSupplementTo">10.1074/jbc.M116.721977</relatedIdentifier>
    <relatedIdentifier relatedIdentifierType="DOI" relationType="IsSupplementTo">10.1038/nature12393</relatedIdentifier>
  </relatedIdentifiers>
  <rightsList>
    <rights rightsURI="https://creativecommons.org/publicdomain/zero/1.0/legalcode">Creative Commons Zero v1.0 Universal</rights>
    <rights rightsURI="info:eu-repo/semantics/openAccess">Open Access</rights>
  </rightsList>
  <descriptions>
    <description descriptionType="Abstract">&lt;p&gt;Curated set of&amp;nbsp;2463 quantitative mutation data points&amp;nbsp;covering 13 secretin-like class B&amp;nbsp;G protein-coupled receptors.&lt;/p&gt;

&lt;p&gt;Annotated according to GPCRdb standards (http://gpcrdb.org/), complemented by GPCRdb Ballesteros-Weinstein numbers assigned&amp;nbsp;using GPCRdb KNIME nodes (https://github.com/3D-e-Chem/knime-gpcrdb).&lt;/p&gt;

&lt;p&gt;The data set is build from data sets published in:&lt;/p&gt;

&lt;p&gt;- Siu et al. Nature 2013,&amp;nbsp;499: 444-449. doi:10.1038/nature12393&lt;/p&gt;

&lt;p&gt;- Hollenstein, de Graaf&amp;nbsp;et al. Tr Pharmacol Sci&amp;nbsp;2014, 35: 12-22. doi: 10.1016/j.tips.2013.11.001&lt;/p&gt;

&lt;p&gt;- Yang, de Graaf et al. J Biol Chem 2016, 291: 12991-3004. doi: 10.1074/jbc.M116.721977&lt;/p&gt;</description>
  </descriptions>
</resource>
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