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Secretin-like class B G protein-coupled receptor (GPCR) mutation data set

de Graaf, Chris


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        <foaf:name>de Graaf, Chris</foaf:name>
        <foaf:givenName>Chris</foaf:givenName>
        <foaf:familyName>de Graaf</foaf:familyName>
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            <foaf:name>Vrije Universiteit Amsterdam</foaf:name>
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    <dct:title>Secretin-like class B G protein-coupled receptor (GPCR) mutation data set</dct:title>
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    <dcat:keyword>G protein-coupled receptor (GPCR)</dcat:keyword>
    <dcat:keyword>site directed mutagenesis</dcat:keyword>
    <dcat:keyword>secretin-like receptors</dcat:keyword>
    <dcat:keyword>class B GPCR</dcat:keyword>
    <dcat:keyword>glucagon receptor (GCGR)</dcat:keyword>
    <dcat:keyword>glucagon like peptide 1 receptor (GLP-1R)</dcat:keyword>
    <dcat:keyword>growth hormone-releasing factor receptor (GHRH)</dcat:keyword>
    <dcat:keyword>gastric inhibitory polypeptide receptor (GIPR)</dcat:keyword>
    <dcat:keyword>calcitonin receptor (CALCR)</dcat:keyword>
    <dcat:keyword>calcitonin receptor-like receptor (CALRL)</dcat:keyword>
    <dcat:keyword>corticotropin releasing hormone receptor 1 (CRFR1)</dcat:keyword>
    <dcat:keyword>corticotropin releasing hormone receptor 2 (CRFR2)</dcat:keyword>
    <dcat:keyword>parathyroid hormone 1 receptor (PTH1R)</dcat:keyword>
    <dcat:keyword>parathyroid hormone 2 receptor (PTH2R)</dcat:keyword>
    <dcat:keyword>secretin receptor (SCTR)</dcat:keyword>
    <dcat:keyword>vasoactive intestinal peptide receptor 1 (VIPR1)</dcat:keyword>
    <dcat:keyword>vasoactive intestinal peptide receptor 2 (VIPR2)</dcat:keyword>
    <dct:issued rdf:datatype="http://www.w3.org/2001/XMLSchema#date">2016-08-24</dct:issued>
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    <dct:relation rdf:resource="https://doi.org/10.1074/jbc.M116.721977"/>
    <dct:relation rdf:resource="https://doi.org/10.1038/nature12393"/>
    <dct:description>&lt;p&gt;Curated set of&amp;nbsp;2463 quantitative mutation data points&amp;nbsp;covering 13 secretin-like class B&amp;nbsp;G protein-coupled receptors.&lt;/p&gt; &lt;p&gt;Annotated according to GPCRdb standards (http://gpcrdb.org/), complemented by GPCRdb Ballesteros-Weinstein numbers assigned&amp;nbsp;using GPCRdb KNIME nodes (https://github.com/3D-e-Chem/knime-gpcrdb).&lt;/p&gt; &lt;p&gt;The data set is build from data sets published in:&lt;/p&gt; &lt;p&gt;- Siu et al. Nature 2013,&amp;nbsp;499: 444-449. doi:10.1038/nature12393&lt;/p&gt; &lt;p&gt;- Hollenstein, de Graaf&amp;nbsp;et al. Tr Pharmacol Sci&amp;nbsp;2014, 35: 12-22. doi: 10.1016/j.tips.2013.11.001&lt;/p&gt; &lt;p&gt;- Yang, de Graaf et al. J Biol Chem 2016, 291: 12991-3004. doi: 10.1074/jbc.M116.721977&lt;/p&gt;</dct:description>
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