DEEP BRAIN PHOTONIC TOOLS FOR CELL-TYPE SPECIFIC TARGETING OF NEURAL DISEASES
Published May 4, 2021 | Version v1
Journal article Open

Wavefront engineering for controlled structuring of far-field intensity and phase patterns from multimodal optical fibers

Creators

  • 1. Istituto Italiano di Tecnologia, Center for Biomolecular Nanotechnologies, Arnesano, LE 73010, Italy

Description

Adaptive optics methods have long been used to perform complex light shaping at the output of a multimode fiber (MMF), with the specific aim of controlling the emitted beam in the near field and enabling the realization of a new generation of endoscopes based on a wide variety of spectroscopic techniques. Gaining control of other emission properties, including the far-field pattern and the phase of the generated beam, would open up the possibility for multimode fibers to act as miniaturized multi-beam steering components and to implement phase-encoded imaging and sensing. In this study, we employ phase modulation using a spatial light modulator at the input of a multimode fiber to generate multiple, low divergence rays with controlled angles and phase at the fiber output. Direct measurement of the output angle and the divergence and phase of the generated beams show how wavefront engineering can be employed to perform complex far-field structuring of the emission of a MMF.

Notes

L.C., M.D.V., and Fe.P acknowledge funding from the European Union's Horizon 2020 Research and Innovation Program under Grant Agreement No. 828972. Fi.P., A.B., and Fe.P. acknowledge funding from the European Research Council under the European Union's Horizon 2020 Research and Innovation Program under Grant Agreement No. 677683. Fi.P., M.D.V. and Fe.P. acknowledge that this project has received funding from the European Union's Horizon 2020 Research and Innovation Program under Grant Agreement No 101016787. M.P. and M.D.V. acknowledge funding from the European Research Council under the European Union's Horizon 2020 Research and Innovation Program under Grant Agreement No. 692943. M.P., Fe.P., and M.D.V. were funded by the U.S. National Institutes of Health (Grant No. 1UF1NS108177-01). M.D.V. was funded by the U.S. National Institutes of Health (Grant No. U01NS094190). M.D.V. and F.P. are founders and hold private equity in Optogenix, a company that develops, produces, and sells technologies to deliver light into the brain.

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Wavefront engineering for controlled structuring o.pdf

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Additional details

Related works

Is identical to
10.1063/5.0044666 (DOI)

Funding

MODEM – Multipoint Optical DEvices for Minimally invasive neural circuits interface 677683
European Commission
BrainBIT – All-optical brain-to-brain behaviour and information transfer 692943
European Commission
DEEPER – DEEP BRAIN PHOTONIC TOOLS FOR CELL-TYPE SPECIFIC TARGETING OF NEURAL DISEASES 101016787
European Commission
Controlling the spatial extent of light-based monitoring and manipulation of neural activity in vivo 1UF1NS108177-01
National Institutes of Health
NanoBRIGHT – BRInGing nano-pHoTonics into the brain 828972
European Commission