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Published August 26, 2014 | Version v3
Dataset Open

Modeling of the Nup84 subcomplex of the Nuclear Pore Complex

  • 1. Laboratory of Mass Spectrometry and Gaseous Ion Chemistry, The Rockefeller University, New York, New York 10065
  • 2. Laboratory of Cellular and Structural Biology, The Rockefeller University, New York, New York 10065
  • 3. Department of Bioengineering and Therapeutic Sciences, Department of Pharmaceutical Chemistry, California Institute for Quantitative Biosciences, Byers Hall, 1700 4th Street, Suite 503B, University of California, San Francisco, San Francisco, California 94158

Contributors

Data manager:

  • 1. University of California, San Francisco, United States.

Description

These scripts demonstrate the use of IMP, MODELLER, and PMI in the modeling of the Nup84 complex using 286 DSS/EDC chemical cross-links and an electron microscopy (EM) 2D class average.

First, MODELLER is used to generate initial structures for the individual components in the Nup84 complex. Then, IMP is used to model these components using DSS/EDC crosslinks and the electron microscopy 2D class average for the entire Nup84 complex.

Files

Fig_6_densities.zip

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