Studies on formation constants of some transition metal complexes containing folic acid as a primary ligand and some amino acids as a secondary ligands

Department of Chemistry, Bangladesh University of Engineering & Technology, Dhaka-1000, Bangladesh

Manuscript received 11 September 2002, revised 9 April 2003. accepted 11 July 2003

The stability constants (∆ log K) of the ternary complexes of copper(ll) and nickel(ll) with folic acid (FA) and some amino acids such as tryptophane (tryp), tyrosine (tyr), dipicolinic acid (DPA) and adenosine triphosphate (ATP) have been determined hy potentiometric method and their redox behaviour have been examined hy cyclic voltammctric method. An astatistical increase in the value of mixed ligand formation constants was observed by small negative or positive value of ∆ log K. The potentiometric and the cyclic voltammetric study show the complexes of Ni^II arc more stable than that of complexes of Cu^II•