5818020
doi
10.5281/zenodo.5818020
oai:zenodo.org:5818020
FORMULATION AND OPTIMIZATION OF FAST DISSOLVING TABLET OF TERBUTALINE SULPHATE BY NOVEL CO-PROCESSING
Mahendra sahu, Anwar Iqbal khan and Dr. Navjot singh
info:eu-repo/semantics/openAccess
Creative Commons Attribution 4.0 International
https://creativecommons.org/licenses/by/4.0/legalcode
<p><em>The present study was to </em><em>formulation and optimization of fast dissolving tablet of terbutaline sulphate by novel co-processing, </em><em>Terbutaline sulphate tablets containing co-processed superdisintegrants exhibited quick disintegration and improved drug dissolution.</em><em> This formulation is more cost effective than aerosol inhalation pumps available. It was found that the total maximum amount of drug from the optimised batch was released in first 4 minutes of the dissolution study. The tablets disintegrated within 50 sec under experimental in vitro laboratory conditions.</em><em> It can be concluded from the present work that co-processed superdisintegrants of crospovidone and croscarmellose are superior to physical mixture of crospovidone and croscarmellose used in Terbutaline sulphate fast dissolving tablets.</em></p>
<p><strong>Keywords: </strong><em>Superdisintegrants, co-processing, disintegration time, excipients, capillary</em></p>
Zenodo
2022-01-04
info:eu-repo/semantics/article
5818019
1641347333.917778
1021532
md5:ff31035578ba0c2aff6b39f067072d71
https://zenodo.org/records/5818020/files/01.b part-final paper3.pdf
public
10.5281/zenodo.5818019
isVersionOf
doi