10.5281/zenodo.5766513
https://zenodo.org/records/5766513
oai:zenodo.org:5766513
UK Health Data Research Alliance
UK Health Data Research Alliance
NHSX
NHSX
Building Trusted Research Environments - Principles and Best Practices; Towards TRE ecosystems
Zenodo
2021
Trusted Research Environment
Best Practices
Principles
Five SAFE
Susheel Varma
Susheel Varma
0000-0003-1687-2754
HDR UK
Tim Hubbard
Tim Hubbard
0000-0002-1767-9318
HDR UK
David Seymour
David Seymour
HDR UK
Nicky Brassington
Nicky Brassington
NHSX
Simon Madden
Simon Madden
NHSX
2021-12-08
10.5281/zenodo.5766512
https://zenodo.org/communities/hdruk
1.0
Creative Commons Attribution 4.0 International
The paper acts as a guide for UK data custodians and other organisations involved in data sharing and information governance both within and beyond the health sectors. It identifies and provides principles, approaches and guidelines for data sharing and linkage practice within TREs, as well as examples of best practices drawn from the experiences of colleagues working in the Alliance and internationally.
The guidelines and principles in the paper are structured around the “Five Safes” framework for the access of health data – safe people, safe projects, safe settings, safe data, safe outputs. The White Paper also sets out principles for the federation of Trusted Research Environments - how they can be linked, to substantially enhance the scale of secure and trustworthy data linkage and research.