Journal article Open Access

LIPID ABNORMALITIES IN NON-DIABETIC, NON-OBESE AND PATIENTS OF HYPERTENSION

Dr Abdur Rahman Abshar


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    <subfield code="a">&lt;p&gt;&lt;strong&gt;&lt;em&gt;Background:&lt;/em&gt;&lt;/strong&gt;&lt;em&gt; Dyslipidemia and hypertension are among the main contributors to the pathogenesis of coronary artery disease, and their coexistence does not increase the risk, but rather increases it.&lt;/em&gt;&lt;/p&gt;

&lt;p&gt;&lt;strong&gt;&lt;em&gt;OBJECTIVE:&lt;/em&gt;&lt;/strong&gt;&lt;em&gt; The aim of this study was to determine the frequency of dyslipidemia in non-obese, non-diabetic hypertensive patients and to compare it with the same frequency in non-obese, non-diabetic, normotensive patients.&lt;/em&gt;&lt;/p&gt;

&lt;p&gt;&lt;strong&gt;&lt;em&gt;Methods:&lt;/em&gt;&lt;/strong&gt;&lt;em&gt; This case-control study was conducted in the Department of Medicine, &lt;/em&gt;&lt;em&gt;Khyber Teaching Hospital Peshawar&lt;/em&gt;&lt;em&gt; for six months duration from January 2021 to June 2021. 120 adults of both sexes were included in the study; 40 non-obese, non-diabetic, hypertensive patients and 80 non-obese, non-diabetic, normotensive individuals. Demographic data and eating habits of each subject were recorded using a questionnaire. Fasting lipid profile and blood glucose of all subjects were evaluated. All data were compared between the two groups.&lt;/em&gt;&lt;/p&gt;

&lt;p&gt;&lt;strong&gt;&lt;em&gt;Results:&lt;/em&gt;&lt;/strong&gt;&lt;em&gt; The hypertensive group showed higher total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C) and triglycerides (TG), and lower high-density lipoprotein cholesterol (HDL-C) values compared to the hypertensive group. Normo-tensive group. In males only, TC, LDL-C, HDL-C abnormalities and TG were more common in the hypertensive group (odds ratio = 2.96, 2.67, 4.28 and 4.57), respectively. HDL-C abnormality in women was similar in both groups (odds ratio = 1.47).&lt;/em&gt;&lt;/p&gt;

&lt;p&gt;&lt;strong&gt;&lt;em&gt;Conclusion:&lt;/em&gt;&lt;/strong&gt;&lt;em&gt; Hypertensive individuals are more likely to have various lipid abnormalities such as total cholesterol, LDL-C, HDL-C (men), and triglycerides compared to the normotensive population.&lt;/em&gt;&lt;/p&gt;

&lt;p&gt;&lt;strong&gt;Keywords:&lt;/strong&gt; &lt;em&gt;Non-obese, Non-diabetic, Hypertensive, Dyslipidemia.&lt;/em&gt;&lt;/p&gt;</subfield>
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