Journal article Open Access

LIPID ABNORMALITIES IN NON-DIABETIC, NON-OBESE AND PATIENTS OF HYPERTENSION

Dr Abdur Rahman Abshar


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{
  "publisher": "Zenodo", 
  "DOI": "10.5281/zenodo.5727806", 
  "author": [
    {
      "family": "Dr Abdur Rahman Abshar"
    }
  ], 
  "issued": {
    "date-parts": [
      [
        2021, 
        11, 
        25
      ]
    ]
  }, 
  "abstract": "<p><strong><em>Background:</em></strong><em> Dyslipidemia and hypertension are among the main contributors to the pathogenesis of coronary artery disease, and their coexistence does not increase the risk, but rather increases it.</em></p>\n\n<p><strong><em>OBJECTIVE:</em></strong><em> The aim of this study was to determine the frequency of dyslipidemia in non-obese, non-diabetic hypertensive patients and to compare it with the same frequency in non-obese, non-diabetic, normotensive patients.</em></p>\n\n<p><strong><em>Methods:</em></strong><em> This case-control study was conducted in the Department of Medicine, </em><em>Khyber Teaching Hospital Peshawar</em><em> for six months duration from January 2021 to June 2021. 120 adults of both sexes were included in the study; 40 non-obese, non-diabetic, hypertensive patients and 80 non-obese, non-diabetic, normotensive individuals. Demographic data and eating habits of each subject were recorded using a questionnaire. Fasting lipid profile and blood glucose of all subjects were evaluated. All data were compared between the two groups.</em></p>\n\n<p><strong><em>Results:</em></strong><em> The hypertensive group showed higher total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C) and triglycerides (TG), and lower high-density lipoprotein cholesterol (HDL-C) values compared to the hypertensive group. Normo-tensive group. In males only, TC, LDL-C, HDL-C abnormalities and TG were more common in the hypertensive group (odds ratio = 2.96, 2.67, 4.28 and 4.57), respectively. HDL-C abnormality in women was similar in both groups (odds ratio = 1.47).</em></p>\n\n<p><strong><em>Conclusion:</em></strong><em> Hypertensive individuals are more likely to have various lipid abnormalities such as total cholesterol, LDL-C, HDL-C (men), and triglycerides compared to the normotensive population.</em></p>\n\n<p><strong>Keywords:</strong> <em>Non-obese, Non-diabetic, Hypertensive, Dyslipidemia.</em></p>", 
  "title": "LIPID ABNORMALITIES IN NON-DIABETIC, NON-OBESE AND PATIENTS OF HYPERTENSION", 
  "type": "article-journal", 
  "id": "5727806"
}
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