Journal article Open Access

LIPID ABNORMALITIES IN NON-DIABETIC, NON-OBESE AND PATIENTS OF HYPERTENSION

Dr Abdur Rahman Abshar

Background: Dyslipidemia and hypertension are among the main contributors to the pathogenesis of coronary artery disease, and their coexistence does not increase the risk, but rather increases it.

OBJECTIVE: The aim of this study was to determine the frequency of dyslipidemia in non-obese, non-diabetic hypertensive patients and to compare it with the same frequency in non-obese, non-diabetic, normotensive patients.

Methods: This case-control study was conducted in the Department of Medicine, Khyber Teaching Hospital Peshawar for six months duration from January 2021 to June 2021. 120 adults of both sexes were included in the study; 40 non-obese, non-diabetic, hypertensive patients and 80 non-obese, non-diabetic, normotensive individuals. Demographic data and eating habits of each subject were recorded using a questionnaire. Fasting lipid profile and blood glucose of all subjects were evaluated. All data were compared between the two groups.

Results: The hypertensive group showed higher total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C) and triglycerides (TG), and lower high-density lipoprotein cholesterol (HDL-C) values compared to the hypertensive group. Normo-tensive group. In males only, TC, LDL-C, HDL-C abnormalities and TG were more common in the hypertensive group (odds ratio = 2.96, 2.67, 4.28 and 4.57), respectively. HDL-C abnormality in women was similar in both groups (odds ratio = 1.47).

Conclusion: Hypertensive individuals are more likely to have various lipid abnormalities such as total cholesterol, LDL-C, HDL-C (men), and triglycerides compared to the normotensive population.

Keywords: Non-obese, Non-diabetic, Hypertensive, Dyslipidemia.

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