Journal article Open Access

Synthesis, characterization and antimicrobial evaluation of some new substituted 1H-indole-2 carboxamide derivatives

Kamal A. Sweidan; Ala'a M. Al-Shamaileha; Mohammad K. Abu Sini; Rajendra Joshi


MARC21 XML Export

<?xml version='1.0' encoding='UTF-8'?>
<record xmlns="http://www.loc.gov/MARC21/slim">
  <leader>00000nam##2200000uu#4500</leader>
  <datafield tag="041" ind1=" " ind2=" ">
    <subfield code="a">eng</subfield>
  </datafield>
  <datafield tag="653" ind1=" " ind2=" ">
    <subfield code="a">Antimicrobial</subfield>
  </datafield>
  <datafield tag="653" ind1=" " ind2=" ">
    <subfield code="a">carboxamide</subfield>
  </datafield>
  <datafield tag="653" ind1=" " ind2=" ">
    <subfield code="a">DEPT-NMR</subfield>
  </datafield>
  <datafield tag="653" ind1=" " ind2=" ">
    <subfield code="a">indole</subfield>
  </datafield>
  <datafield tag="653" ind1=" " ind2=" ">
    <subfield code="a">synthesis</subfield>
  </datafield>
  <controlfield tag="005">20211109134837.0</controlfield>
  <controlfield tag="001">5657220</controlfield>
  <datafield tag="700" ind1=" " ind2=" ">
    <subfield code="a">Ala'a M. Al-Shamaileha</subfield>
  </datafield>
  <datafield tag="700" ind1=" " ind2=" ">
    <subfield code="a">Mohammad K. Abu Sini</subfield>
  </datafield>
  <datafield tag="700" ind1=" " ind2=" ">
    <subfield code="a">Rajendra Joshi</subfield>
  </datafield>
  <datafield tag="856" ind1="4" ind2=" ">
    <subfield code="s">217155</subfield>
    <subfield code="z">md5:7e21642555c38153999ef460a22e9ba2</subfield>
    <subfield code="u">https://zenodo.org/record/5657220/files/17) September-25.pdf</subfield>
  </datafield>
  <datafield tag="542" ind1=" " ind2=" ">
    <subfield code="l">open</subfield>
  </datafield>
  <datafield tag="260" ind1=" " ind2=" ">
    <subfield code="c">2020-09-01</subfield>
  </datafield>
  <datafield tag="909" ind1="C" ind2="O">
    <subfield code="p">openaire</subfield>
    <subfield code="o">oai:zenodo.org:5657220</subfield>
  </datafield>
  <datafield tag="909" ind1="C" ind2="4">
    <subfield code="c">1557-1562</subfield>
    <subfield code="n">Sept 2020</subfield>
    <subfield code="p">Journal of Indian Chemical Society</subfield>
    <subfield code="v">Vol. 97, No. 9b</subfield>
  </datafield>
  <datafield tag="100" ind1=" " ind2=" ">
    <subfield code="a">Kamal A. Sweidan</subfield>
  </datafield>
  <datafield tag="245" ind1=" " ind2=" ">
    <subfield code="a">Synthesis, characterization and antimicrobial evaluation of some new substituted 1H-indole-2 carboxamide derivatives</subfield>
  </datafield>
  <datafield tag="540" ind1=" " ind2=" ">
    <subfield code="u">https://creativecommons.org/licenses/by/4.0/legalcode</subfield>
    <subfield code="a">Creative Commons Attribution 4.0 International</subfield>
  </datafield>
  <datafield tag="650" ind1="1" ind2="7">
    <subfield code="a">cc-by</subfield>
    <subfield code="2">opendefinition.org</subfield>
  </datafield>
  <datafield tag="520" ind1=" " ind2=" ">
    <subfield code="a">&lt;p&gt;Department of Chemistry, The University of Jordan, Amman, 11942, Jordan&lt;/p&gt;

&lt;p&gt;Faculty of Pharmacy, Al-Zaytoonah University of Jordan, Amman, 11733, Jordan&lt;/p&gt;

&lt;p&gt;Department of Chemical Science and Engineering, School of Engineering, Kathmandu University, Nepal&lt;/p&gt;

&lt;p&gt;E-mail: rajendra.joshi@k.edu.np&lt;/p&gt;

&lt;p&gt;Manuscript received online 19 July 2020, accepted 28 August 2020&lt;/p&gt;

&lt;p&gt;A new series of 1H-indole-2-carboxamide derivatives has been prepared by simple procedures in good yields, followed by complete characterization using nuclear magnetic resonance, infrared spectroscopy, high resolution mass spectrometry and elemental analysis techniques. The prepared compounds have been tested as potential antifungal and anti-bacterial (Grampositive and Gram-negative) agents. The antifungal and antibacterial results indicated that carboxylic acid compounds exhibited a weak bioactivity; even with replacement of carboxylic acid group with ester, no significant difference in activities was observed relative to standard commercial drugs.&lt;/p&gt;</subfield>
  </datafield>
  <datafield tag="773" ind1=" " ind2=" ">
    <subfield code="n">doi</subfield>
    <subfield code="i">isVersionOf</subfield>
    <subfield code="a">10.5281/zenodo.5657219</subfield>
  </datafield>
  <datafield tag="024" ind1=" " ind2=" ">
    <subfield code="a">10.5281/zenodo.5657220</subfield>
    <subfield code="2">doi</subfield>
  </datafield>
  <datafield tag="980" ind1=" " ind2=" ">
    <subfield code="a">publication</subfield>
    <subfield code="b">article</subfield>
  </datafield>
</record>
32
18
views
downloads
All versions This version
Views 3232
Downloads 1818
Data volume 3.9 MB3.9 MB
Unique views 2323
Unique downloads 1818

Share

Cite as