Journal article Open Access
Synthesis, characterization, thermal stability and antimicrobial activities of transition metal complexes of 8-[2-amino-2-(4-hydroxyphenyl)-acetyl]amino-4- methyl-7-oxo-2-thia-6-azabicyclo[4.2.0]oct-4-ene-5-carboxylic acid
Suman Malik; Sonal Wankhede
Sadhu Vaswani P.G. College, Bairagarh, Bhopal-462 030, Madhya Pradesh, India
E-mail : sonal2107@gmail.com
Manuscript received online 15 February 2016, accepted 17 February 2016
The complexes of 8-[2-amino-2-(4-hydroxyphenyl)-acetyl]amino-4-methyl-7-oxo-2-thia-6-azabicyclo[4.2.0]oct-4-
ene-5-carboxylic acid (L) with FeIII, Nill Iand RuIII of composition [MLX2] (M = FeIII, NiII and RuIII; X = Cl) were
prepared and characterized by elemental analysis, molar conductance, magnetic susceptibility, IR, UV-Visible, Mass,
SEM and thermogravimetric studies. As elemental analysis suggests ML stoichiometry for all metals, conductivity data
suggests that all the complexes are non-electrolyte in nature. Similarly, magnetic susceptibility, spectral and thermal
studies suggest that all the complexes possess octahedral geometry. The synthesized metal complexes were screened for
their antimicrobial activities against bacteria Escherichia coli and Staphylococcus aureus. The results were found to exhibit
potent biological activity against both bacteria which increased in the forms of their metal complexes.
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- Publication date:
- June 1, 2016
- DOI:
-
- Keyword(s):
- Synthesis characterization metal complex IR UV-Vis antimicrobial
- Published in:
- Journal of Indian Chemical Society: vol. 93 pp. 593-598 (june 2016).
- License (for files):
- Creative Commons Attribution 4.0 International