TINOSPORA CORDIFOLIA: PHYTOCHEMICAL SCREENING & ANTHELMINTIC STUDY OF IT'S DIFFERENT EXTRACTS

The present study attempts to evaluate the phytochemicals parameters of Tinospora cordifolia leaves belong to family Menispermaceae that found in throughout India. The plant is used in the treatment of heart disease, leprosy, helmenthiasis, cancer, bone fracture, pain, skin disease, poisonous insect, snake bite and eye disorders. Its stem is highly nutritive and digestive purposes. Tinospora cordifolia is also used as a blood purifier that removes defective and damaged red blood cells from peripheral blood circulation by stimulating liver and spleen. Aim: The aim of the study is to investigate Phytochemical screening and anthelmintic study of Tinospora cordifolia by Petroleum ether and aqueous extract. Result: The percentage yield of Petroleum ether and aqueous extract were found to 7.82%w/w and 9.54 %w/w (Table-1). The preliminary phytochemical screening on the leaf extract was carried out by subjecting the different extracts to qualitative test for the identification of various plant constituents. It showed the presence of alkaloids, glycosides, saponins, anthraquinone, terpenoids, phlobatanin like compounds (Table-2) but do not show the presence of carbohydrate in Petroleum ether, phenolic, flavonoid and lignin. The Powder analysis and fluorescence was observed in ultra-short, ultra-long and visible. The results were shown in (table-3 and 4). Results: The results (Table-5) depict the time taken for paralysis and death of earthworms after the treatment with the test extracts at the selected concentrations. The data revealed that the aqueous extract has a better wormicidal effect than Petroleum ether extract with compared with the standard drug Albendazole. Further study is required to find out the novel phytoconstituents responsible for anthelmintic action against various helminthes.

KEY WORD: Tinospora cordifolia, Phytochemical screening, Albendazole, Anthelmintic Activity,