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Published October 16, 2021 | Version v1
Journal article Open

TO DETERMINE THE MEAN CHANGE OF TRANSURETHRAL RESECTION OF PROSTATE (TURP) ON ERECTILE FUNCTION IN PATIENTS OF BENIGN PROSTATIC HYPERPLASIA (BPH) IN A TERTIARY CARE HOSPITAL

Description

Introduction: Benign prostatic hyperplasia (BPH) affects approximately 210 million men globally and is a major cause of lower urinary tract symptoms (LUTS) in men. Transurethral resection of the prostate (TURP), the standard surgical therapy for the treatment of bladder outlet obstruction (BOO) caused by benign prostatic hyperplasia (BPH), is also reported to cause sexual dysfunction as well. It is known that TURP may cause retrograde ejaculation, but its effect on erectile function is still controversial.

Objective: To determine the mean change of transurethral resection of prostate (TURP) on erectile function in patients of benign prostatic hyperplasia (BPH) in a tertiary care hospital.

Study Design: Quasi Experimental study.

Setting: The study was completed at department of Urology, Sindh Institute of Urology and Transplantation, Karachi.

Duration of Study: 01-Nov-2018 to 30-April-2019.

Patients and Methods: A total number of 261 patients who presented with acute urinary retention due to BPH and planned for TURP having age 50-70 years were included in this study. Before TURP validated International Index of Erectile Function (IIEF) scoring proforma was filled for all patients and EF score was calculated. TURP was done by consultant urologists having a minimum of 3 years post-fellowship experience. After 1 month of surgery the patients were called for follow up visit to fulfill the IIEF questionnaire. After receiving the filled questionnaire back, IIEF score was calculated.

Results: Mean age of patients was 60.47+5.43 years. Mean duration of BPH was 15.83+6.48 months. Mean prostate volume was 64.12+11.46 ml. There was significant difference in pre-op and post-op IIEF score. Mean pre-op IIEF was 16.72+5.29. and mean post-op IIEF 11.50+3.01 (p-value <0.001). stratification of age, duration of BPH and pre-op prostate volume was done. There was no significant effect of these confounder variables on pre-op and post-op erectile dysfunction.

Conclusion: Transurethral resection of prostate is significantly associated with reduction in erectile function in patients of benign prostatic hyperplasia. 

Keywords: benign prostatic hyperplasia, erectile dysfunction, IIEF score,

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