Dataset Open Access

Single-cell analysis of patient-derived PDAC organoids reveals cell state heterogeneity and a conserved developmental hierarchy

Krieger, Teresa Gabriela; Le Blanc, Solange; Jabs, Julia; Ten, Foo Wei; Ishaque, Naveed; Jechow, Katharina; Debnath, Olivia; Leonhardt, Carl-Stephan; Giri, Anamika; Eils, Roland; Strobel, Oliver; Conrad, Christian


JSON Export

{
  "files": [
    {
      "links": {
        "self": "https://zenodo.org/api/files/67b2a981-f405-4d4e-bf79-f661988bbe81/pdac03_counts_full.csv"
      }, 
      "checksum": "md5:2d5a3247839cb539b2cf7e812527f7f8", 
      "bucket": "67b2a981-f405-4d4e-bf79-f661988bbe81", 
      "key": "pdac03_counts_full.csv", 
      "type": "csv", 
      "size": 242240315
    }, 
    {
      "links": {
        "self": "https://zenodo.org/api/files/67b2a981-f405-4d4e-bf79-f661988bbe81/pdac06_counts_full.csv"
      }, 
      "checksum": "md5:3b3247e014a3c2a4f8703fedb3fb105f", 
      "bucket": "67b2a981-f405-4d4e-bf79-f661988bbe81", 
      "key": "pdac06_counts_full.csv", 
      "type": "csv", 
      "size": 292308078
    }, 
    {
      "links": {
        "self": "https://zenodo.org/api/files/67b2a981-f405-4d4e-bf79-f661988bbe81/pdac100_counts_full.csv"
      }, 
      "checksum": "md5:e9c130b959909f474dae494ca844af8a", 
      "bucket": "67b2a981-f405-4d4e-bf79-f661988bbe81", 
      "key": "pdac100_counts_full.csv", 
      "type": "csv", 
      "size": 374717956
    }, 
    {
      "links": {
        "self": "https://zenodo.org/api/files/67b2a981-f405-4d4e-bf79-f661988bbe81/pdac18_counts_full.csv"
      }, 
      "checksum": "md5:ca260e85dab9dcffcc43c3bb6529c972", 
      "bucket": "67b2a981-f405-4d4e-bf79-f661988bbe81", 
      "key": "pdac18_counts_full.csv", 
      "type": "csv", 
      "size": 300425641
    }, 
    {
      "links": {
        "self": "https://zenodo.org/api/files/67b2a981-f405-4d4e-bf79-f661988bbe81/pdac19_counts_full.csv"
      }, 
      "checksum": "md5:065b4fc0832307d35b7133ea903269f8", 
      "bucket": "67b2a981-f405-4d4e-bf79-f661988bbe81", 
      "key": "pdac19_counts_full.csv", 
      "type": "csv", 
      "size": 273152753
    }, 
    {
      "links": {
        "self": "https://zenodo.org/api/files/67b2a981-f405-4d4e-bf79-f661988bbe81/pdac22_counts_full.csv"
      }, 
      "checksum": "md5:1f3ad3493d8fe6bfe7cd36b3060f9f08", 
      "bucket": "67b2a981-f405-4d4e-bf79-f661988bbe81", 
      "key": "pdac22_counts_full.csv", 
      "type": "csv", 
      "size": 307735238
    }, 
    {
      "links": {
        "self": "https://zenodo.org/api/files/67b2a981-f405-4d4e-bf79-f661988bbe81/pdac26_counts_full.csv"
      }, 
      "checksum": "md5:5aba4bacd797d32fd8cb643775a3f444", 
      "bucket": "67b2a981-f405-4d4e-bf79-f661988bbe81", 
      "key": "pdac26_counts_full.csv", 
      "type": "csv", 
      "size": 162083592
    }, 
    {
      "links": {
        "self": "https://zenodo.org/api/files/67b2a981-f405-4d4e-bf79-f661988bbe81/pdac27_counts_full.csv"
      }, 
      "checksum": "md5:71c00b6b6684f6bdd35488a503eae049", 
      "bucket": "67b2a981-f405-4d4e-bf79-f661988bbe81", 
      "key": "pdac27_counts_full.csv", 
      "type": "csv", 
      "size": 226130711
    }, 
    {
      "links": {
        "self": "https://zenodo.org/api/files/67b2a981-f405-4d4e-bf79-f661988bbe81/pdac29_counts_full.csv"
      }, 
      "checksum": "md5:6ea6e972713925a57e7d0bab5a8b75f6", 
      "bucket": "67b2a981-f405-4d4e-bf79-f661988bbe81", 
      "key": "pdac29_counts_full.csv", 
      "type": "csv", 
      "size": 249099577
    }, 
    {
      "links": {
        "self": "https://zenodo.org/api/files/67b2a981-f405-4d4e-bf79-f661988bbe81/pdac32_counts_full.csv"
      }, 
      "checksum": "md5:9dbb06ab9424285def108e854cbdfe6e", 
      "bucket": "67b2a981-f405-4d4e-bf79-f661988bbe81", 
      "key": "pdac32_counts_full.csv", 
      "type": "csv", 
      "size": 234326981
    }, 
    {
      "links": {
        "self": "https://zenodo.org/api/files/67b2a981-f405-4d4e-bf79-f661988bbe81/pdac37_counts_full.csv"
      }, 
      "checksum": "md5:964f042f837f4acbbdb64d615cb0dfd0", 
      "bucket": "67b2a981-f405-4d4e-bf79-f661988bbe81", 
      "key": "pdac37_counts_full.csv", 
      "type": "csv", 
      "size": 355166765
    }, 
    {
      "links": {
        "self": "https://zenodo.org/api/files/67b2a981-f405-4d4e-bf79-f661988bbe81/pdac39_counts_full.csv"
      }, 
      "checksum": "md5:bf511a896a55944fc200cab9acdf566d", 
      "bucket": "67b2a981-f405-4d4e-bf79-f661988bbe81", 
      "key": "pdac39_counts_full.csv", 
      "type": "csv", 
      "size": 231534913
    }, 
    {
      "links": {
        "self": "https://zenodo.org/api/files/67b2a981-f405-4d4e-bf79-f661988bbe81/pdac42_counts_full.csv"
      }, 
      "checksum": "md5:114437ecc3fd968ddb530d5e9a84aa85", 
      "bucket": "67b2a981-f405-4d4e-bf79-f661988bbe81", 
      "key": "pdac42_counts_full.csv", 
      "type": "csv", 
      "size": 192729716
    }, 
    {
      "links": {
        "self": "https://zenodo.org/api/files/67b2a981-f405-4d4e-bf79-f661988bbe81/pdac47_counts_full.csv"
      }, 
      "checksum": "md5:705d51faef6bbee8dc1fe441f8a5a552", 
      "bucket": "67b2a981-f405-4d4e-bf79-f661988bbe81", 
      "key": "pdac47_counts_full.csv", 
      "type": "csv", 
      "size": 258684157
    }, 
    {
      "links": {
        "self": "https://zenodo.org/api/files/67b2a981-f405-4d4e-bf79-f661988bbe81/pdac48_counts_full.csv"
      }, 
      "checksum": "md5:714831c8b3afe2daf4d80cfcc2d179d2", 
      "bucket": "67b2a981-f405-4d4e-bf79-f661988bbe81", 
      "key": "pdac48_counts_full.csv", 
      "type": "csv", 
      "size": 243254251
    }, 
    {
      "links": {
        "self": "https://zenodo.org/api/files/67b2a981-f405-4d4e-bf79-f661988bbe81/pdac64_counts_full.csv"
      }, 
      "checksum": "md5:6a1431cefd9624d21bb0217b8e1f0d81", 
      "bucket": "67b2a981-f405-4d4e-bf79-f661988bbe81", 
      "key": "pdac64_counts_full.csv", 
      "type": "csv", 
      "size": 207995564
    }, 
    {
      "links": {
        "self": "https://zenodo.org/api/files/67b2a981-f405-4d4e-bf79-f661988bbe81/pdac72_counts_full.csv"
      }, 
      "checksum": "md5:28499777dda75f3586fa48e7b0dcddf8", 
      "bucket": "67b2a981-f405-4d4e-bf79-f661988bbe81", 
      "key": "pdac72_counts_full.csv", 
      "type": "csv", 
      "size": 312698405
    }, 
    {
      "links": {
        "self": "https://zenodo.org/api/files/67b2a981-f405-4d4e-bf79-f661988bbe81/pdac73_counts_full.csv"
      }, 
      "checksum": "md5:3464c297447585fac16a792bf83df131", 
      "bucket": "67b2a981-f405-4d4e-bf79-f661988bbe81", 
      "key": "pdac73_counts_full.csv", 
      "type": "csv", 
      "size": 348104162
    }, 
    {
      "links": {
        "self": "https://zenodo.org/api/files/67b2a981-f405-4d4e-bf79-f661988bbe81/pdac75_counts_full.csv"
      }, 
      "checksum": "md5:b3bee2152869b8f9173778dd2a6e8006", 
      "bucket": "67b2a981-f405-4d4e-bf79-f661988bbe81", 
      "key": "pdac75_counts_full.csv", 
      "type": "csv", 
      "size": 291527543
    }, 
    {
      "links": {
        "self": "https://zenodo.org/api/files/67b2a981-f405-4d4e-bf79-f661988bbe81/pdac80_counts_full.csv"
      }, 
      "checksum": "md5:8f95f03f45229f4fd6dff9cf40eb6e4d", 
      "bucket": "67b2a981-f405-4d4e-bf79-f661988bbe81", 
      "key": "pdac80_counts_full.csv", 
      "type": "csv", 
      "size": 203804267
    }, 
    {
      "links": {
        "self": "https://zenodo.org/api/files/67b2a981-f405-4d4e-bf79-f661988bbe81/pdac81_counts_full.csv"
      }, 
      "checksum": "md5:56d71a39d54cd80e5002fc293c8baa15", 
      "bucket": "67b2a981-f405-4d4e-bf79-f661988bbe81", 
      "key": "pdac81_counts_full.csv", 
      "type": "csv", 
      "size": 285209241
    }, 
    {
      "links": {
        "self": "https://zenodo.org/api/files/67b2a981-f405-4d4e-bf79-f661988bbe81/pdac83_counts_full.csv"
      }, 
      "checksum": "md5:439c86d79fcd4d510ae057327fed06c4", 
      "bucket": "67b2a981-f405-4d4e-bf79-f661988bbe81", 
      "key": "pdac83_counts_full.csv", 
      "type": "csv", 
      "size": 272606615
    }, 
    {
      "links": {
        "self": "https://zenodo.org/api/files/67b2a981-f405-4d4e-bf79-f661988bbe81/pdac84_counts_full.csv"
      }, 
      "checksum": "md5:51fd46344330643939a1a40b08872a2f", 
      "bucket": "67b2a981-f405-4d4e-bf79-f661988bbe81", 
      "key": "pdac84_counts_full.csv", 
      "type": "csv", 
      "size": 176709950
    }, 
    {
      "links": {
        "self": "https://zenodo.org/api/files/67b2a981-f405-4d4e-bf79-f661988bbe81/pdac85_counts_full.csv"
      }, 
      "checksum": "md5:755c2fea81fa477f95801f0564aab58a", 
      "bucket": "67b2a981-f405-4d4e-bf79-f661988bbe81", 
      "key": "pdac85_counts_full.csv", 
      "type": "csv", 
      "size": 252781661
    }, 
    {
      "links": {
        "self": "https://zenodo.org/api/files/67b2a981-f405-4d4e-bf79-f661988bbe81/pdac89_counts_full.csv"
      }, 
      "checksum": "md5:a1139ba8794368d1353b1c188cf2dbea", 
      "bucket": "67b2a981-f405-4d4e-bf79-f661988bbe81", 
      "key": "pdac89_counts_full.csv", 
      "type": "csv", 
      "size": 258249502
    }
  ], 
  "owners": [
    142419
  ], 
  "doi": "10.5281/zenodo.5552404", 
  "stats": {
    "version_unique_downloads": 15.0, 
    "unique_views": 31.0, 
    "views": 48.0, 
    "version_views": 48.0, 
    "unique_downloads": 15.0, 
    "version_unique_views": 31.0, 
    "volume": 24020158332.0, 
    "version_downloads": 93.0, 
    "downloads": 93.0, 
    "version_volume": 24020158332.0
  }, 
  "links": {
    "doi": "https://doi.org/10.5281/zenodo.5552404", 
    "conceptdoi": "https://doi.org/10.5281/zenodo.5552403", 
    "bucket": "https://zenodo.org/api/files/67b2a981-f405-4d4e-bf79-f661988bbe81", 
    "conceptbadge": "https://zenodo.org/badge/doi/10.5281/zenodo.5552403.svg", 
    "html": "https://zenodo.org/record/5552404", 
    "latest_html": "https://zenodo.org/record/5552404", 
    "badge": "https://zenodo.org/badge/doi/10.5281/zenodo.5552404.svg", 
    "latest": "https://zenodo.org/api/records/5552404"
  }, 
  "conceptdoi": "10.5281/zenodo.5552403", 
  "created": "2021-10-06T14:15:21.689363+00:00", 
  "updated": "2021-10-07T01:48:31.285542+00:00", 
  "conceptrecid": "5552403", 
  "revision": 2, 
  "id": 5552404, 
  "metadata": {
    "access_right_category": "success", 
    "doi": "10.5281/zenodo.5552404", 
    "description": "<p>scRNA-seq read count matrices from patient-derived PDAC organoids.</p>", 
    "license": {
      "id": "CC-BY-4.0"
    }, 
    "title": "Single-cell analysis of patient-derived PDAC organoids reveals cell state heterogeneity and a conserved developmental hierarchy", 
    "relations": {
      "version": [
        {
          "count": 1, 
          "index": 0, 
          "parent": {
            "pid_type": "recid", 
            "pid_value": "5552403"
          }, 
          "is_last": true, 
          "last_child": {
            "pid_type": "recid", 
            "pid_value": "5552404"
          }
        }
      ]
    }, 
    "publication_date": "2021-10-05", 
    "creators": [
      {
        "affiliation": "Digital Health Center, Berlin Institute of Health (BIH)/Charit\u00e9-Universit\u00e4tsmedizin Berlin, Berlin, Germany", 
        "name": "Krieger, Teresa Gabriela"
      }, 
      {
        "affiliation": "European Pancreas Center, Department of General Surgery, Heidelberg University Hospital, Heidelberg, Germany", 
        "name": "Le Blanc, Solange"
      }, 
      {
        "affiliation": "Division of Theoretical Bioinformatics, German Cancer Research Center (DKFZ), Heidelberg, Germany", 
        "name": "Jabs, Julia"
      }, 
      {
        "affiliation": "Digital Health Center, Berlin Institute of Health (BIH)/Charit\u00e9-Universit\u00e4tsmedizin Berlin, Berlin, Germany", 
        "name": "Ten, Foo Wei"
      }, 
      {
        "affiliation": "Digital Health Center, Berlin Institute of Health (BIH)/Charit\u00e9-Universit\u00e4tsmedizin Berlin, Berlin, Germany", 
        "name": "Ishaque, Naveed"
      }, 
      {
        "affiliation": "Digital Health Center, Berlin Institute of Health (BIH)/Charit\u00e9-Universit\u00e4tsmedizin Berlin, Berlin, Germany", 
        "name": "Jechow, Katharina"
      }, 
      {
        "affiliation": "Digital Health Center, Berlin Institute of Health (BIH)/Charit\u00e9-Universit\u00e4tsmedizin Berlin, Berlin, Germany", 
        "name": "Debnath, Olivia"
      }, 
      {
        "affiliation": "European Pancreas Center, Department of General Surgery, Heidelberg University Hospital, Heidelberg, Germany", 
        "name": "Leonhardt, Carl-Stephan"
      }, 
      {
        "affiliation": "Digital Health Center, Berlin Institute of Health (BIH)/Charit\u00e9-Universit\u00e4tsmedizin Berlin, Berlin, Germany", 
        "name": "Giri, Anamika"
      }, 
      {
        "affiliation": "Digital Health Center, Berlin Institute of Health (BIH)/Charit\u00e9-Universit\u00e4tsmedizin Berlin, Berlin, Germany", 
        "name": "Eils, Roland"
      }, 
      {
        "affiliation": "European Pancreas Center, Department of General Surgery, Heidelberg University Hospital, Heidelberg, Germany", 
        "name": "Strobel, Oliver"
      }, 
      {
        "affiliation": "Digital Health Center, Berlin Institute of Health (BIH)/Charit\u00e9-Universit\u00e4tsmedizin Berlin, Berlin, Germany", 
        "name": "Conrad, Christian"
      }
    ], 
    "access_right": "open", 
    "resource_type": {
      "type": "dataset", 
      "title": "Dataset"
    }, 
    "related_identifiers": [
      {
        "scheme": "doi", 
        "identifier": "10.5281/zenodo.5552403", 
        "relation": "isVersionOf"
      }
    ]
  }
}
48
93
views
downloads
All versions This version
Views 4848
Downloads 9393
Data volume 24.0 GB24.0 GB
Unique views 3131
Unique downloads 1515

Share

Cite as