Dataset Open Access

Single-cell analysis of patient-derived PDAC organoids reveals cell state heterogeneity and a conserved developmental hierarchy

Krieger, Teresa Gabriela; Le Blanc, Solange; Jabs, Julia; Ten, Foo Wei; Ishaque, Naveed; Jechow, Katharina; Debnath, Olivia; Leonhardt, Carl-Stephan; Giri, Anamika; Eils, Roland; Strobel, Oliver; Conrad, Christian


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  <identifier identifierType="DOI">10.5281/zenodo.5552404</identifier>
  <creators>
    <creator>
      <creatorName>Krieger, Teresa Gabriela</creatorName>
      <givenName>Teresa Gabriela</givenName>
      <familyName>Krieger</familyName>
      <affiliation>Digital Health Center, Berlin Institute of Health (BIH)/Charité-Universitätsmedizin Berlin, Berlin, Germany</affiliation>
    </creator>
    <creator>
      <creatorName>Le Blanc, Solange</creatorName>
      <givenName>Solange</givenName>
      <familyName>Le Blanc</familyName>
      <affiliation>European Pancreas Center, Department of General Surgery, Heidelberg University Hospital, Heidelberg, Germany</affiliation>
    </creator>
    <creator>
      <creatorName>Jabs, Julia</creatorName>
      <givenName>Julia</givenName>
      <familyName>Jabs</familyName>
      <affiliation>Division of Theoretical Bioinformatics, German Cancer Research Center (DKFZ), Heidelberg, Germany</affiliation>
    </creator>
    <creator>
      <creatorName>Ten, Foo Wei</creatorName>
      <givenName>Foo Wei</givenName>
      <familyName>Ten</familyName>
      <affiliation>Digital Health Center, Berlin Institute of Health (BIH)/Charité-Universitätsmedizin Berlin, Berlin, Germany</affiliation>
    </creator>
    <creator>
      <creatorName>Ishaque, Naveed</creatorName>
      <givenName>Naveed</givenName>
      <familyName>Ishaque</familyName>
      <affiliation>Digital Health Center, Berlin Institute of Health (BIH)/Charité-Universitätsmedizin Berlin, Berlin, Germany</affiliation>
    </creator>
    <creator>
      <creatorName>Jechow, Katharina</creatorName>
      <givenName>Katharina</givenName>
      <familyName>Jechow</familyName>
      <affiliation>Digital Health Center, Berlin Institute of Health (BIH)/Charité-Universitätsmedizin Berlin, Berlin, Germany</affiliation>
    </creator>
    <creator>
      <creatorName>Debnath, Olivia</creatorName>
      <givenName>Olivia</givenName>
      <familyName>Debnath</familyName>
      <affiliation>Digital Health Center, Berlin Institute of Health (BIH)/Charité-Universitätsmedizin Berlin, Berlin, Germany</affiliation>
    </creator>
    <creator>
      <creatorName>Leonhardt, Carl-Stephan</creatorName>
      <givenName>Carl-Stephan</givenName>
      <familyName>Leonhardt</familyName>
      <affiliation>European Pancreas Center, Department of General Surgery, Heidelberg University Hospital, Heidelberg, Germany</affiliation>
    </creator>
    <creator>
      <creatorName>Giri, Anamika</creatorName>
      <givenName>Anamika</givenName>
      <familyName>Giri</familyName>
      <affiliation>Digital Health Center, Berlin Institute of Health (BIH)/Charité-Universitätsmedizin Berlin, Berlin, Germany</affiliation>
    </creator>
    <creator>
      <creatorName>Eils, Roland</creatorName>
      <givenName>Roland</givenName>
      <familyName>Eils</familyName>
      <affiliation>Digital Health Center, Berlin Institute of Health (BIH)/Charité-Universitätsmedizin Berlin, Berlin, Germany</affiliation>
    </creator>
    <creator>
      <creatorName>Strobel, Oliver</creatorName>
      <givenName>Oliver</givenName>
      <familyName>Strobel</familyName>
      <affiliation>European Pancreas Center, Department of General Surgery, Heidelberg University Hospital, Heidelberg, Germany</affiliation>
    </creator>
    <creator>
      <creatorName>Conrad, Christian</creatorName>
      <givenName>Christian</givenName>
      <familyName>Conrad</familyName>
      <affiliation>Digital Health Center, Berlin Institute of Health (BIH)/Charité-Universitätsmedizin Berlin, Berlin, Germany</affiliation>
    </creator>
  </creators>
  <titles>
    <title>Single-cell analysis of patient-derived PDAC organoids reveals cell state heterogeneity and a conserved developmental hierarchy</title>
  </titles>
  <publisher>Zenodo</publisher>
  <publicationYear>2021</publicationYear>
  <dates>
    <date dateType="Issued">2021-10-05</date>
  </dates>
  <resourceType resourceTypeGeneral="Dataset"/>
  <alternateIdentifiers>
    <alternateIdentifier alternateIdentifierType="url">https://zenodo.org/record/5552404</alternateIdentifier>
  </alternateIdentifiers>
  <relatedIdentifiers>
    <relatedIdentifier relatedIdentifierType="DOI" relationType="IsVersionOf">10.5281/zenodo.5552403</relatedIdentifier>
  </relatedIdentifiers>
  <rightsList>
    <rights rightsURI="https://creativecommons.org/licenses/by/4.0/legalcode">Creative Commons Attribution 4.0 International</rights>
    <rights rightsURI="info:eu-repo/semantics/openAccess">Open Access</rights>
  </rightsList>
  <descriptions>
    <description descriptionType="Abstract">&lt;p&gt;scRNA-seq read count matrices from patient-derived PDAC organoids.&lt;/p&gt;</description>
  </descriptions>
</resource>
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