CBC PROFILE AND BIOCHEMICAL ANALYSIS OF COVID-19 PATIENTS

Introduction: COVID-19 is basically a RNA virus and the nucleic acid is about 30 kb long, positive in sense, single stranded and polyadenylated. Objectives: The main objective of the study is to analyse the CBC value and biochemical analysis of COVID-19 patients. Material and methods: This cross sectional study was conducted in Punjab Health Department during January 2021 to June 2021. Outpatients with suspected COVID-19 having initial respiratory signs (including sore throat without shortness of breath), fever, cough, muscle ache, and headache were included. Pharyngeal swab samples were collected for COVID-19 test on presentation. Results: Patients with positive RT-PCR had significantly higher NEU count (p = 0.0001), and CRP (p = 0.04), LDH (p = 0.0001), AST (p = 0.001), ALT (p = 0.0001), and Urea (p = 0.001) levels in serum. In addition, patients with positive RT-PCR had lower WBC count (p = 0.0001) and serum albumin level (p = 0.0001) compared to others. Two hundred cases with the mean age of 41.3± 14.6 (range: 19-78) years were studied (0.53% male). Conclusion: It is concluded that based on the findings of this study ALT, CRP, NEU, LDH, and Urea have very good accuracy in predicting cases with positive RT-PCR for COVID-19, respectively.