Reaction |
R_PI4P5K_18_0_20_4 R_PI4P5K_18_0_20_4
|
PI4P5K 18 0 20 4
[0.0
1000.0]
(200576 or 23396 or 8394 or 8395 or 8396 or 5305 or 79837) |
➞ |
M_atp_c + M_pail45p_hs_18_0_20_4_c ➞ M_adp_c + M_h_c + M_pail345p_hs_18_0_20_4_c |
|
|
|
|
|
Reaction |
R_PI34P5K_18_0_20_4 R_PI34P5K_18_0_20_4
|
PI34P5K 18 0 20 4
[0.0
1000.0]
(8394 or 8395 or 23396) |
➞ |
M_atp_c + M_pail34p_hs_18_0_20_4_c ➞ M_adp_c + M_h_c + M_pail345p_hs_18_0_20_4_c |
|
|
|
|
|
Reaction |
R_PI4P3K_18_0_20_4 R_PI4P3K_18_0_20_4
|
PI4P3K 18 0 20 4
[0.0
1000.0]
(5286 or 5287 or 5288 or 5290 or 5291 or 5293 or 5294 or 23533 or 5296 or 10870 or 8503 or 5295) |
➞ |
M_atp_c + M_pail4p_hs_18_0_20_4_c ➞ M_adp_c + M_h_c + M_pail34p_hs_18_0_20_4_c |
|
|
|
|
|
Reaction |
R_PI4PLC_18_0_20_4 R_PI4PLC_18_0_20_4
|
PI4PLC 18 0 20 4
[0.0
1000.0]
(113026 or 23236 or 84812 or 9651 or 257068 or 89869 or 5330 or 5331 or 5332 or 5333 or 5334 or 5335 or 5336 or 51196 or 23007) |
➞ |
M_h2o_c + M_pail4p_hs_18_0_20_4_c ➞ M_dag_hs_18_0_20_4_c + M_h_c + M_mi14p_c |
|
|
|
|
|
Reaction |
R_PIK4_18_0_20_4 R_PIK4_18_0_20_4
|
PIK4 18 0 20 4
[0.0
1000.0]
(5297 or 5298 or 55361) |
➞ |
M_atp_c + M_pail_hs_18_0_20_4_c ➞ M_adp_c + M_h_c + M_pail4p_hs_18_0_20_4_c |
|
|
|
|
|
Reaction |
R_PIPLC_18_0_20_4 R_PIPLC_18_0_20_4
|
PIPLC 18 0 20 4
[0.0
1000.0]
(113026 or 23236 or 84812 or 257068 or 9651 or 89869 or 5330 or 5331 or 5332 or 5333 or 5334 or 5335 or 5336 or 51196 or 23007) |
➞ |
M_h2o_c + M_pail_hs_18_0_20_4_c ➞ M_dag_hs_18_0_20_4_c + M_h_c + M_mi1p__D_c |
|
|
|
|
|
Reaction |
R_CDIPTr_18_0_20_4 R_CDIPTr_18_0_20_4
|
CDIPTr 18 0 20 4
[0.0
1000.0]
10423 |
➞ |
M_cdpdag_hs_18_0_20_4_c + M_inost_c ➞ M_cmp_c + M_h_c + M_pail_hs_18_0_20_4_c |
|
|
|
|
|
Reaction |
R_CDS_18_0_20_4 R_CDS_18_0_20_4
|
CDS 18 0 20 4
[0.0
1000.0]
1040 |
➞ |
M_ctp_c + M_h_c + M_pa_hs_18_0_20_4_c ➞ M_cdpdag_hs_18_0_20_4_c + M_ppi_c |
|
|
|
|
|
Reaction |
R_LPS2_18_0_20_4 R_LPS2_18_0_20_4
|
LPS2 18 0 20 4
[0.0
1000.0]
4023 |
➞ |
M_dag_hs_18_0_20_4_c + M_h2o_c ➞ M_arachd_c + M_h_c + M_mag_hs_18_0_c |
|
|
|
|
|
Reaction |
R_DAGK_hs_18_0_20_4 R_DAGK_hs_18_0_20_4
|
DAGK hs 18 0 20 4
[-1000.0
1000.0]
(1606 or 1607 or 1608 or 1609 or 9162 or 8525 or 8526 or 8527 or 160851) |
⇆ |
M_adp_c + M_h_c + M_pa_hs_18_0_20_4_c ⇆ M_atp_c + M_dag_hs_18_0_20_4_c |
|
|
|
|
|
Reaction |
R_PLA2_2_18_0_20_4 R_PLA2_2_18_0_20_4
|
PLA2 2 18 0 20 4
[0.0
1000.0]
(5320 or 8398) |
➞ |
M_h2o_c + M_pchol_hs_18_0_20_4_c ➞ M_arachd_c + M_h_c + M_lpchol_hs_18_0_c |
|
|
|
|
|
Reaction |
R_PPAP_18_2_20_4 R_PPAP_18_2_20_4
|
PPAP 18 2 20 4
[0.0
1000.0]
(8611 or 8612 or 8613) |
➞ |
M_h2o_c + M_pa_hs_18_2_20_4_c ➞ M_dag_hs_18_2_20_4_c + M_pi_c |
|
|
|
|
|
Reaction |
R_CEPTC_18_0_20_4 R_CEPTC_18_0_20_4
|
CEPTC 18 0 20 4
[0.0
1000.0]
(56994 or 10390) |
➞ |
M_cdpchol_c + M_dag_hs_18_0_20_4_c ➞ M_cmp_c + M_h_c + M_pchol_hs_18_0_20_4_c |
|
|
|
|
|
Reaction |
R_AGPAT1_18_2_20_4 R_AGPAT1_18_2_20_4
|
AGPAT1 18 2 20 4
[0.0
1000.0]
(137964 or 56894 or 10554 or 10555 or 55326 or 56895) |
➞ |
M_alpha_hs_18_2_c + M_arachdcoa_c ➞ M_coa_c + M_pa_hs_18_2_20_4_c |
|
|
|
|
|
Reaction |
R_PPAP_18_1_20_4 R_PPAP_18_1_20_4
|
PPAP 18 1 20 4
[0.0
1000.0]
(8611 or 8612 or 8613) |
➞ |
M_h2o_c + M_pa_hs_18_1_20_4_c ➞ M_dag_hs_18_1_20_4_c + M_pi_c |
|
|
|
|
|
Reaction |
R_AGPAT1_18_1_20_4 R_AGPAT1_18_1_20_4
|
AGPAT1 18 1 20 4
[0.0
1000.0]
(137964 or 56894 or 10554 or 10555 or 55326 or 56895) |
➞ |
M_alpha_hs_18_1_c + M_arachdcoa_c ➞ M_coa_c + M_pa_hs_18_1_20_4_c |
|
|
|
|
|
Reaction |
R_PI45PLC_18_2_18_2 R_PI45PLC_18_2_18_2
|
PI45PLC 18 2 18 2
[0.0
1000.0]
(113026 or 23236 or 84812 or 9651 or 257068 or 89869 or 5330 or 5331 or 5332 or 5333 or 5334 or 5335 or 5336 or 51196 or 23007) |
➞ |
M_h2o_c + M_pail45p_hs_18_2_18_2_c ➞ M_dag_hs_18_2_18_2_c + M_h_c + M_mi145p_c |
|
|
|
|
|
Reaction |
R_PSSA1_hs_18_0_20_4 R_PSSA1_hs_18_0_20_4
|
PSSA1 hs 18 0 20 4
[-1000.0
1000.0]
9791 |
⇆ |
M_chol_c + M_ps_hs_18_0_20_4_c ⇆ M_pchol_hs_18_0_20_4_c + M_ser__L_c |
|
|
|
|
|
Reaction |
R_PI345P3P_18_2_18_2 R_PI345P3P_18_2_18_2
|
PI345P3P 18 2 18 2
[0.0
1000.0]
5728 |
➞ |
M_h2o_c + M_pail345p_hs_18_2_18_2_c ➞ M_pail45p_hs_18_2_18_2_c + M_pi_c |
|
|
|
|
|
Reaction |
R_PI4P5K_18_2_18_2 R_PI4P5K_18_2_18_2
|
PI4P5K 18 2 18 2
[0.0
1000.0]
(200576 or 23396 or 8394 or 8395 or 8396 or 5305 or 79837) |
➞ |
M_atp_c + M_pail45p_hs_18_2_18_2_c ➞ M_adp_c + M_h_c + M_pail345p_hs_18_2_18_2_c |
|
|
|
|
|
Reaction |
R_PI34P5K_18_2_18_2 R_PI34P5K_18_2_18_2
|
PI34P5K 18 2 18 2
[0.0
1000.0]
(8394 or 8395 or 23396) |
➞ |
M_atp_c + M_pail34p_hs_18_2_18_2_c ➞ M_adp_c + M_h_c + M_pail345p_hs_18_2_18_2_c |
|
|
|
|
|
Reaction |
R_PI45PLC_18_1_18_2 R_PI45PLC_18_1_18_2
|
Phosphatidylinositol 4,5-bisphosphate phospholipase C (C18:1, C18:2)
[0.0
1000.0]
(113026 or 23236 or 84812 or 9651 or 257068 or 89869 or 5330 or 5331 or 5332 or 5333 or 5334 or 5335 or 5336 or 51196 or 23007) |
➞ |
M_h2o_c + M_pail45p_hs_18_1_18_2_c ➞ M_dag_hs_18_1_18_2_c + M_h_c + M_mi145p_c |
|
|
|
|
|
Reaction |
R_PSSA2_hs_18_0_20_4 R_PSSA2_hs_18_0_20_4
|
PSSA2 hs 18 0 20 4
[-1000.0
1000.0]
81490 |
⇆ |
M_pe_hs_18_0_20_4_c + M_ser__L_c ⇆ M_etha_c + M_ps_hs_18_0_20_4_c |
|
|
|
|
|
Reaction |
R_PI345P3P_18_1_18_2 R_PI345P3P_18_1_18_2
|
PI345P3P 18 1 18 2
[0.0
1000.0]
5728 |
➞ |
M_h2o_c + M_pail345p_hs_18_1_18_2_c ➞ M_pail45p_hs_18_1_18_2_c + M_pi_c |
|
|
|
|
|
Reaction |
R_PI4P5K_18_1_18_2 R_PI4P5K_18_1_18_2
|
PI4P5K 18 1 18 2
[0.0
1000.0]
(200576 or 23396 or 8394 or 8395 or 8396 or 5305 or 79837) |
➞ |
M_atp_c + M_pail45p_hs_18_1_18_2_c ➞ M_adp_c + M_h_c + M_pail345p_hs_18_1_18_2_c |
|
|
|
|
|
Reaction |
R_PI34P5K_18_1_18_2 R_PI34P5K_18_1_18_2
|
PI34P5K 18 1 18 2
[0.0
1000.0]
(8394 or 8395 or 23396) |
➞ |
M_atp_c + M_pail34p_hs_18_1_18_2_c ➞ M_adp_c + M_h_c + M_pail345p_hs_18_1_18_2_c |
|
|
|
|
|
Reaction |
R_PI4P3K_18_1_18_2 R_PI4P3K_18_1_18_2
|
PI4P3K 18 1 18 2
[0.0
1000.0]
(5286 or 5287 or 5288 or 5290 or 5291 or 5293 or 5294 or 23533 or 5296 or 10870 or 8503 or 5295) |
➞ |
M_atp_c + M_pail4p_hs_18_1_18_2_c ➞ M_adp_c + M_h_c + M_pail34p_hs_18_1_18_2_c |
|
|
|
|
|
Reaction |
R_PI4PLC_18_1_18_2 R_PI4PLC_18_1_18_2
|
Phosphatidylinositol 4-phosphate phospholipase C (C18:1,C18:2)
[0.0
1000.0]
(113026 or 23236 or 84812 or 9651 or 257068 or 89869 or 5330 or 5331 or 5332 or 5333 or 5334 or 5335 or 5336 or 51196 or 23007) |
➞ |
M_h2o_c + M_pail4p_hs_18_1_18_2_c ➞ M_dag_hs_18_1_18_2_c + M_h_c + M_mi14p_c |
|
|
|
|
|
Reaction |
R_PI4P3K_18_2_18_2 R_PI4P3K_18_2_18_2
|
PI4P3K 18 2 18 2
[0.0
1000.0]
(5286 or 5287 or 5288 or 5290 or 5291 or 5293 or 5294 or 23533 or 5296 or 10870 or 8503 or 5295) |
➞ |
M_atp_c + M_pail4p_hs_18_2_18_2_c ➞ M_adp_c + M_h_c + M_pail34p_hs_18_2_18_2_c |
|
|
|
|
|
Reaction |
R_PI4PLC_18_2_18_2 R_PI4PLC_18_2_18_2
|
PI4PLC 18 2 18 2
[0.0
1000.0]
(113026 or 23236 or 84812 or 9651 or 257068 or 89869 or 5330 or 5331 or 5332 or 5333 or 5334 or 5335 or 5336 or 51196 or 23007) |
➞ |
M_h2o_c + M_pail4p_hs_18_2_18_2_c ➞ M_dag_hs_18_2_18_2_c + M_h_c + M_mi14p_c |
|
|
|
|
|
Reaction |
R_PIK4_18_2_18_2 R_PIK4_18_2_18_2
|
PIK4 18 2 18 2
[0.0
1000.0]
(5297 or 5298 or 55361) |
➞ |
M_atp_c + M_pail_hs_18_2_18_2_c ➞ M_adp_c + M_h_c + M_pail4p_hs_18_2_18_2_c |
|
|
|
|
|
Reaction |
R_PIPLC_18_2_18_2 R_PIPLC_18_2_18_2
|
PIPLC 18 2 18 2
[0.0
1000.0]
(113026 or 23236 or 84812 or 257068 or 9651 or 89869 or 5330 or 5331 or 5332 or 5333 or 5334 or 5335 or 5336 or 51196 or 23007) |
➞ |
M_h2o_c + M_pail_hs_18_2_18_2_c ➞ M_dag_hs_18_2_18_2_c + M_h_c + M_mi1p__D_c |
|
|
|
|
|
Reaction |
R_CDIPTr_18_2_18_2 R_CDIPTr_18_2_18_2
|
CDIPTr 18 2 18 2
[0.0
1000.0]
10423 |
➞ |
M_cdpdag_hs_18_2_18_2_c + M_inost_c ➞ M_cmp_c + M_h_c + M_pail_hs_18_2_18_2_c |
|
|
|
|
|
Reaction |
R_CDS_18_2_18_2 R_CDS_18_2_18_2
|
CDS 18 2 18 2
[0.0
1000.0]
1040 |
➞ |
M_ctp_c + M_h_c + M_pa_hs_18_2_18_2_c ➞ M_cdpdag_hs_18_2_18_2_c + M_ppi_c |
|
|
|
|
|
Reaction |
R_LPS2_18_2_18_2 R_LPS2_18_2_18_2
|
LPS2 18 2 18 2
[0.0
1000.0]
4023 |
➞ |
M_dag_hs_18_2_18_2_c + M_h2o_c ➞ M_h_c + M_lnlc_c + M_mag_hs_18_2_c |
|
|
|
|
|
Reaction |
R_PIK4_18_1_18_2 R_PIK4_18_1_18_2
|
Phosphatidylinositol 4-kinase (C18:1,C18:2)
[0.0
1000.0]
(5297 or 5298 or 55361) |
➞ |
M_atp_c + M_pail_hs_18_1_18_2_c ➞ M_adp_c + M_h_c + M_pail4p_hs_18_1_18_2_c |
|
|
|
|
|
Reaction |
R_PIPLC_18_1_18_2 R_PIPLC_18_1_18_2
|
Phosphatidylinositol phospholipase C (C18:1,C18:2)
[0.0
1000.0]
(113026 or 23236 or 84812 or 257068 or 9651 or 89869 or 5330 or 5331 or 5332 or 5333 or 5334 or 5335 or 5336 or 51196 or 23007) |
➞ |
M_h2o_c + M_pail_hs_18_1_18_2_c ➞ M_dag_hs_18_1_18_2_c + M_h_c + M_mi1p__D_c |
|
|
|
|
|
Reaction |
R_DAGK_hs_18_2_18_2 R_DAGK_hs_18_2_18_2
|
DAGK hs 18 2 18 2
[-1000.0
1000.0]
(1606 or 1607 or 1608 or 1609 or 9162 or 8525 or 8526 or 8527 or 160851) |
⇆ |
M_adp_c + M_h_c + M_pa_hs_18_2_18_2_c ⇆ M_atp_c + M_dag_hs_18_2_18_2_c |
|
|
|
|
|
Reaction |
R_CDIPTr_18_1_18_2 R_CDIPTr_18_1_18_2
|
Phosphatidylinositol synthase (Homo sapiens, C18:1,C18:2)
[0.0
1000.0]
10423 |
➞ |
M_cdpdag_hs_18_1_18_2_c + M_inost_c ➞ M_cmp_c + M_h_c + M_pail_hs_18_1_18_2_c |
|
|
|
|
|
Reaction |
R_CEPTE_18_0_20_4 R_CEPTE_18_0_20_4
|
CEPTE 18 0 20 4
[0.0
1000.0]
10390 |
➞ |
M_cdpea_c + M_dag_hs_18_0_20_4_c ➞ M_cmp_c + M_h_c + M_pe_hs_18_0_20_4_c |
|
|
|
|
|
Reaction |
R_CDS_18_1_18_2 R_CDS_18_1_18_2
|
Phosphatidate cytidylyltransferase (C18:1,C18:2)
[0.0
1000.0]
1040 |
➞ |
M_ctp_c + M_h_c + M_pa_hs_18_1_18_2_c ➞ M_cdpdag_hs_18_1_18_2_c + M_ppi_c |
|
|
|
|
|
Reaction |
R_LPS2_18_1_18_2 R_LPS2_18_1_18_2
|
LPS2 18 1 18 2
[0.0
1000.0]
4023 |
➞ |
M_dag_hs_18_1_18_2_c + M_h2o_c ➞ M_h_c + M_lnlc_c + M_mag_hs_18_1_c |
|
|
|
|
|
Reaction |
R_DAGK_hs_18_1_18_2 R_DAGK_hs_18_1_18_2
|
Diacylglycerol phosphate kinase (homo sapiens, C18:1,C18:2)
[-1000.0
1000.0]
(1606 or 1607 or 1608 or 1609 or 9162 or 8525 or 8526 or 8527 or 160851) |
⇆ |
M_adp_c + M_h_c + M_pa_hs_18_1_18_2_c ⇆ M_atp_c + M_dag_hs_18_1_18_2_c |
|
|
|
|
|
Reaction |
R_PLA2_2_18_1_18_2 R_PLA2_2_18_1_18_2
|
Phospholipase A2 (C18:1,C18:2)
[0.0
1000.0]
(5320 or 8398) |
➞ |
M_h2o_c + M_pchol_hs_18_1_18_2_c ➞ M_h_c + M_lnlc_c + M_lpchol_hs_18_1_c |
|
|
|
|
|
Reaction |
R_PLA2_2_18_2_18_2 R_PLA2_2_18_2_18_2
|
PLA2 2 18 2 18 2
[0.0
1000.0]
(5320 or 8398) |
➞ |
M_h2o_c + M_pchol_hs_18_2_18_2_c ➞ M_h_c + M_lnlc_c + M_lpchol_hs_18_2_c |
|
|
|
|
|
Reaction |
R_CEPTC_18_2_18_2 R_CEPTC_18_2_18_2
|
CEPTC 18 2 18 2
[0.0
1000.0]
(56994 or 10390) |
➞ |
M_cdpchol_c + M_dag_hs_18_2_18_2_c ➞ M_cmp_c + M_h_c + M_pchol_hs_18_2_18_2_c |
|
|
|
|
|
Reaction |
R_PSSA1_hs_18_2_18_2 R_PSSA1_hs_18_2_18_2
|
PSSA1 hs 18 2 18 2
[-1000.0
1000.0]
9791 |
⇆ |
M_chol_c + M_ps_hs_18_2_18_2_c ⇆ M_pchol_hs_18_2_18_2_c + M_ser__L_c |
|
|
|
|
|
Reaction |
R_PSSA2_hs_18_2_18_2 R_PSSA2_hs_18_2_18_2
|
PSSA2 hs 18 2 18 2
[-1000.0
1000.0]
81490 |
⇆ |
M_pe_hs_18_2_18_2_c + M_ser__L_c ⇆ M_etha_c + M_ps_hs_18_2_18_2_c |
|
|
|
|
|
Reaction |
R_CEPTE_18_2_18_2 R_CEPTE_18_2_18_2
|
CEPTE 18 2 18 2
[0.0
1000.0]
10390 |
➞ |
M_cdpea_c + M_dag_hs_18_2_18_2_c ➞ M_cmp_c + M_h_c + M_pe_hs_18_2_18_2_c |
|
|
|
|
|
Reaction |
R_PPAP_18_2_18_2 R_PPAP_18_2_18_2
|
PPAP 18 2 18 2
[0.0
1000.0]
(8611 or 8612 or 8613) |
➞ |
M_h2o_c + M_pa_hs_18_2_18_2_c ➞ M_dag_hs_18_2_18_2_c + M_pi_c |
|
|
|
|
|
Reaction |
R_CEPTC_18_1_18_2 R_CEPTC_18_1_18_2
|
Choline phosphotransferase (C18:1, C18:2)
[0.0
1000.0]
(56994 or 10390) |
➞ |
M_cdpchol_c + M_dag_hs_18_1_18_2_c ➞ M_cmp_c + M_h_c + M_pchol_hs_18_1_18_2_c |
|
|
|
|
|
Reaction |
R_PSSA1_hs_18_1_18_2 R_PSSA1_hs_18_1_18_2
|
PSSA1 hs 18 1 18 2
[-1000.0
1000.0]
9791 |
⇆ |
M_chol_c + M_ps_hs_18_1_18_2_c ⇆ M_pchol_hs_18_1_18_2_c + M_ser__L_c |
|
|
|
|
|
Reaction |
R_PSSA2_hs_18_1_18_2 R_PSSA2_hs_18_1_18_2
|
PSSA2 hs 18 1 18 2
[-1000.0
1000.0]
81490 |
⇆ |
M_pe_hs_18_1_18_2_c + M_ser__L_c ⇆ M_etha_c + M_ps_hs_18_1_18_2_c |
|
|
|
|
|
Reaction |
R_CEPTE_18_1_18_2 R_CEPTE_18_1_18_2
|
Ethanolamine phosphotransferase (C18:1,C18:2)
[0.0
1000.0]
10390 |
➞ |
M_cdpea_c + M_dag_hs_18_1_18_2_c ➞ M_cmp_c + M_h_c + M_pe_hs_18_1_18_2_c |
|
|
|
|
|
Reaction |
R_AGPAT1_18_2_18_2 R_AGPAT1_18_2_18_2
|
AGPAT1 18 2 18 2
[0.0
1000.0]
(137964 or 56894 or 10554 or 10555 or 55326 or 56895) |
➞ |
M_alpha_hs_18_2_c + M_lnlccoa_c ➞ M_coa_c + M_pa_hs_18_2_18_2_c |
|
|
|
|
|
Reaction |
R_PI45PLC_18_1_20_4 R_PI45PLC_18_1_20_4
|
PI45PLC 18 1 20 4
[0.0
1000.0]
(113026 or 23236 or 84812 or 9651 or 257068 or 89869 or 5330 or 5331 or 5332 or 5333 or 5334 or 5335 or 5336 or 51196 or 23007) |
➞ |
M_h2o_c + M_pail45p_hs_18_1_20_4_c ➞ M_dag_hs_18_1_20_4_c + M_h_c + M_mi145p_c |
|
|
|
|
|
Reaction |
R_PI345P3P_18_1_20_4 R_PI345P3P_18_1_20_4
|
PI345P3P 18 1 20 4
[0.0
1000.0]
5728 |
➞ |
M_h2o_c + M_pail345p_hs_18_1_20_4_c ➞ M_pail45p_hs_18_1_20_4_c + M_pi_c |
|
|
|
|
|
Reaction |
R_PPAP_18_1_18_2 R_PPAP_18_1_18_2
|
Phosphatidic acid phosphatase (C18:1,C18:2)
[0.0
1000.0]
(8611 or 8612 or 8613) |
➞ |
M_h2o_c + M_pa_hs_18_1_18_2_c ➞ M_dag_hs_18_1_18_2_c + M_pi_c |
|
|
|
|
|
Reaction |
R_PPAP_18_0_20_4 R_PPAP_18_0_20_4
|
PPAP 18 0 20 4
[0.0
1000.0]
(8611 or 8612 or 8613) |
➞ |
M_h2o_c + M_pa_hs_18_0_20_4_c ➞ M_dag_hs_18_0_20_4_c + M_pi_c |
|
|
|
|
|
Reaction |
R_AGPAT1_18_1_18_2 R_AGPAT1_18_1_18_2
|
AGPAT1 18 1 18 2
[0.0
1000.0]
(137964 or 56894 or 10554 or 10555 or 55326 or 56895) |
➞ |
M_alpha_hs_18_1_c + M_lnlccoa_c ➞ M_coa_c + M_pa_hs_18_1_18_2_c |
|
|
|
|
|
Reaction |
R_PI45PLC_18_1_18_1 R_PI45PLC_18_1_18_1
|
Phosphatidylinositol 4,5-bisphosphate phospholipase C (C18:1, C18:1)
[0.0
1000.0]
(113026 or 23236 or 84812 or 9651 or 257068 or 89869 or 5330 or 5331 or 5332 or 5333 or 5334 or 5335 or 5336 or 51196 or 23007) |
➞ |
M_h2o_c + M_pail45p_hs_18_1_18_1_c ➞ M_dag_hs_18_1_18_1_c + M_h_c + M_mi145p_c |
|
|
|
|
|
Reaction |
R_PI4P5K_18_1_20_4 R_PI4P5K_18_1_20_4
|
PI4P5K 18 1 20 4
[0.0
1000.0]
(200576 or 23396 or 8394 or 8395 or 8396 or 5305 or 79837) |
➞ |
M_atp_c + M_pail45p_hs_18_1_20_4_c ➞ M_adp_c + M_h_c + M_pail345p_hs_18_1_20_4_c |
|
|
|
|
|
Reaction |
R_PI34P5K_18_1_20_4 R_PI34P5K_18_1_20_4
|
PI34P5K 18 1 20 4
[0.0
1000.0]
(8394 or 8395 or 23396) |
➞ |
M_atp_c + M_pail34p_hs_18_1_20_4_c ➞ M_adp_c + M_h_c + M_pail345p_hs_18_1_20_4_c |
|
|
|
|
|
Reaction |
R_PI4P3K_18_1_20_4 R_PI4P3K_18_1_20_4
|
PI4P3K 18 1 20 4
[0.0
1000.0]
(5286 or 5287 or 5288 or 5290 or 5291 or 5293 or 5294 or 23533 or 5296 or 10870 or 8503 or 5295) |
➞ |
M_atp_c + M_pail4p_hs_18_1_20_4_c ➞ M_adp_c + M_h_c + M_pail34p_hs_18_1_20_4_c |
|
|
|
|
|
Reaction |
R_PI4PLC_18_1_20_4 R_PI4PLC_18_1_20_4
|
PI4PLC 18 1 20 4
[0.0
1000.0]
(113026 or 23236 or 84812 or 9651 or 257068 or 89869 or 5330 or 5331 or 5332 or 5333 or 5334 or 5335 or 5336 or 51196 or 23007) |
➞ |
M_h2o_c + M_pail4p_hs_18_1_20_4_c ➞ M_dag_hs_18_1_20_4_c + M_h_c + M_mi14p_c |
|
|
|
|
|
Reaction |
R_PI345P3P_18_1_18_1 R_PI345P3P_18_1_18_1
|
PI345P3P 18 1 18 1
[0.0
1000.0]
5728 |
➞ |
M_h2o_c + M_pail345p_hs_18_1_18_1_c ➞ M_pail45p_hs_18_1_18_1_c + M_pi_c |
|
|
|
|
|
Reaction |
R_PI4P5K_18_1_18_1 R_PI4P5K_18_1_18_1
|
PI4P5K 18 1 18 1
[0.0
1000.0]
(200576 or 23396 or 8394 or 8395 or 8396 or 5305 or 79837) |
➞ |
M_atp_c + M_pail45p_hs_18_1_18_1_c ➞ M_adp_c + M_h_c + M_pail345p_hs_18_1_18_1_c |
|
|
|
|
|
Reaction |
R_PIK4_18_1_20_4 R_PIK4_18_1_20_4
|
PIK4 18 1 20 4
[0.0
1000.0]
(5297 or 5298 or 55361) |
➞ |
M_atp_c + M_pail_hs_18_1_20_4_c ➞ M_adp_c + M_h_c + M_pail4p_hs_18_1_20_4_c |
|
|
|
|
|
Reaction |
R_AGPAT1_18_0_20_4 R_AGPAT1_18_0_20_4
|
AGPAT1 18 0 20 4
[0.0
1000.0]
(137964 or 56894 or 10554 or 10555 or 55326 or 56895) |
➞ |
M_alpha_hs_18_0_c + M_arachdcoa_c ➞ M_coa_c + M_pa_hs_18_0_20_4_c |
|
|
|
|
|
Reaction |
R_PIPLC_18_1_20_4 R_PIPLC_18_1_20_4
|
PIPLC 18 1 20 4
[0.0
1000.0]
(113026 or 23236 or 84812 or 257068 or 9651 or 89869 or 5330 or 5331 or 5332 or 5333 or 5334 or 5335 or 5336 or 51196 or 23007) |
➞ |
M_h2o_c + M_pail_hs_18_1_20_4_c ➞ M_dag_hs_18_1_20_4_c + M_h_c + M_mi1p__D_c |
|
|
|
|
|
Reaction |
R_PI34P5K_18_1_18_1 R_PI34P5K_18_1_18_1
|
PI34P5K 18 1 18 1
[0.0
1000.0]
(8394 or 8395 or 23396) |
➞ |
M_atp_c + M_pail34p_hs_18_1_18_1_c ➞ M_adp_c + M_h_c + M_pail345p_hs_18_1_18_1_c |
|
|
|
|
|
Reaction |
R_PI4P3K_18_1_18_1 R_PI4P3K_18_1_18_1
|
PI4P3K 18 1 18 1
[0.0
1000.0]
(5286 or 5287 or 5288 or 5290 or 5291 or 5293 or 5294 or 23533 or 5296 or 10870 or 8503 or 5295) |
➞ |
M_atp_c + M_pail4p_hs_18_1_18_1_c ➞ M_adp_c + M_h_c + M_pail34p_hs_18_1_18_1_c |
|
|
|
|
|
Reaction |
R_CDIPTr_18_1_20_4 R_CDIPTr_18_1_20_4
|
CDIPTr 18 1 20 4
[0.0
1000.0]
10423 |
➞ |
M_cdpdag_hs_18_1_20_4_c + M_inost_c ➞ M_cmp_c + M_h_c + M_pail_hs_18_1_20_4_c |
|
|
|
|
|
Reaction |
R_PI45PLC_18_0_18_2 R_PI45PLC_18_0_18_2
|
PI45PLC 18 0 18 2
[0.0
1000.0]
(113026 or 23236 or 84812 or 9651 or 257068 or 89869 or 5330 or 5331 or 5332 or 5333 or 5334 or 5335 or 5336 or 51196 or 23007) |
➞ |
M_h2o_c + M_pail45p_hs_18_0_18_2_c ➞ M_dag_hs_18_0_18_2_c + M_h_c + M_mi145p_c |
|
|
|
|
|
Reaction |
R_CDS_18_1_20_4 R_CDS_18_1_20_4
|
CDS 18 1 20 4
[0.0
1000.0]
1040 |
➞ |
M_ctp_c + M_h_c + M_pa_hs_18_1_20_4_c ➞ M_cdpdag_hs_18_1_20_4_c + M_ppi_c |
|
|
|
|
|
Reaction |
R_LPS2_18_1_20_4 R_LPS2_18_1_20_4
|
LPS2 18 1 20 4
[0.0
1000.0]
4023 |
➞ |
M_dag_hs_18_1_20_4_c + M_h2o_c ➞ M_arachd_c + M_h_c + M_mag_hs_18_1_c |
|
|
|
|
|
Reaction |
R_DAGK_hs_18_1_20_4 R_DAGK_hs_18_1_20_4
|
DAGK hs 18 1 20 4
[-1000.0
1000.0]
(1606 or 1607 or 1608 or 1609 or 9162 or 8525 or 8526 or 8527 or 160851) |
⇆ |
M_adp_c + M_h_c + M_pa_hs_18_1_20_4_c ⇆ M_atp_c + M_dag_hs_18_1_20_4_c |
|
|
|
|
|
Reaction |
R_PLA2_2_18_1_20_4 R_PLA2_2_18_1_20_4
|
PLA2 2 18 1 20 4
[0.0
1000.0]
(5320 or 8398) |
➞ |
M_h2o_c + M_pchol_hs_18_1_20_4_c ➞ M_arachd_c + M_h_c + M_lpchol_hs_18_1_c |
|
|
|
|
|
Reaction |
R_PI4PLC_18_1_18_1 R_PI4PLC_18_1_18_1
|
Phosphatidylinositol 4-phosphate phospholipase C (C18:1,C18:1)
[0.0
1000.0]
(113026 or 23236 or 84812 or 9651 or 257068 or 89869 or 5330 or 5331 or 5332 or 5333 or 5334 or 5335 or 5336 or 51196 or 23007) |
➞ |
M_h2o_c + M_pail4p_hs_18_1_18_1_c ➞ M_dag_hs_18_1_18_1_c + M_h_c + M_mi14p_c |
|
|
|
|
|
Reaction |
R_PIK4_18_1_18_1 R_PIK4_18_1_18_1
|
Phosphatidylinositol 4-kinase (C18:1,C18:1)
[0.0
1000.0]
(5297 or 5298 or 55361) |
➞ |
M_atp_c + M_pail_hs_18_1_18_1_c ➞ M_adp_c + M_h_c + M_pail4p_hs_18_1_18_1_c |
|
|
|
|
|
Reaction |
R_PIPLC_18_1_18_1 R_PIPLC_18_1_18_1
|
Phosphatidylinositol phospholipase C (C18:1,C18:1)
[0.0
1000.0]
(113026 or 23236 or 84812 or 257068 or 9651 or 89869 or 5330 or 5331 or 5332 or 5333 or 5334 or 5335 or 5336 or 51196 or 23007) |
➞ |
M_h2o_c + M_pail_hs_18_1_18_1_c ➞ M_dag_hs_18_1_18_1_c + M_h_c + M_mi1p__D_c |
|
|
|
|
|
Reaction |
R_CDIPTr_18_1_18_1 R_CDIPTr_18_1_18_1
|
Phosphatidylinositol synthase (Homo sapiens, C18:1,C18:1)
[0.0
1000.0]
10423 |
➞ |
M_cdpdag_hs_18_1_18_1_c + M_inost_c ➞ M_cmp_c + M_h_c + M_pail_hs_18_1_18_1_c |
|
|
|
|
|
Reaction |
R_CDS_18_1_18_1 R_CDS_18_1_18_1
|
Phosphatidate cytidylyltransferase (C18:1,C18:1)
[0.0
1000.0]
1040 |
➞ |
M_ctp_c + M_h_c + M_pa_hs_18_1_18_1_c ➞ M_cdpdag_hs_18_1_18_1_c + M_ppi_c |
|
|
|
|
|
Reaction |
R_CEPTC_18_1_20_4 R_CEPTC_18_1_20_4
|
CEPTC 18 1 20 4
[0.0
1000.0]
(56994 or 10390) |
➞ |
M_cdpchol_c + M_dag_hs_18_1_20_4_c ➞ M_cmp_c + M_h_c + M_pchol_hs_18_1_20_4_c |
|
|
|
|
|
Reaction |
R_PSSA1_hs_18_1_20_4 R_PSSA1_hs_18_1_20_4
|
PSSA1 hs 18 1 20 4
[-1000.0
1000.0]
9791 |
⇆ |
M_chol_c + M_ps_hs_18_1_20_4_c ⇆ M_pchol_hs_18_1_20_4_c + M_ser__L_c |
|
|
|
|
|
Reaction |
R_PI345P3P_18_0_18_2 R_PI345P3P_18_0_18_2
|
PI345P3P 18 0 18 2
[0.0
1000.0]
5728 |
➞ |
M_h2o_c + M_pail345p_hs_18_0_18_2_c ➞ M_pail45p_hs_18_0_18_2_c + M_pi_c |
|
|
|
|
|
Reaction |
R_PSSA2_hs_18_1_20_4 R_PSSA2_hs_18_1_20_4
|
PSSA2 hs 18 1 20 4
[-1000.0
1000.0]
81490 |
⇆ |
M_pe_hs_18_1_20_4_c + M_ser__L_c ⇆ M_etha_c + M_ps_hs_18_1_20_4_c |
|
|
|
|
|
Reaction |
R_LPS2_18_1_18_1 R_LPS2_18_1_18_1
|
LPS2 18 1 18 1
[0.0
1000.0]
4023 |
➞ |
M_dag_hs_18_1_18_1_c + M_h2o_c ➞ M_h_c + M_mag_hs_18_1_c + M_ocdcea_c |
|
|
|
|
|
Reaction |
R_DAGK_hs_18_1_18_1 R_DAGK_hs_18_1_18_1
|
Diacylglycerol phosphate kinase (homo sapiens, C18:1,C18:1)
[-1000.0
1000.0]
(1606 or 1607 or 1608 or 1609 or 9162 or 8525 or 8526 or 8527 or 160851) |
⇆ |
M_adp_c + M_h_c + M_pa_hs_18_1_18_1_c ⇆ M_atp_c + M_dag_hs_18_1_18_1_c |
|
|
|
|
|
Reaction |
R_PLA2_2_18_1_18_1 R_PLA2_2_18_1_18_1
|
Phospholipase A2 (C18:1,C18:1)
[0.0
1000.0]
(5320 or 8398) |
➞ |
M_h2o_c + M_pchol_hs_18_1_18_1_c ➞ M_h_c + M_lpchol_hs_18_1_c + M_ocdcea_c |
|
|
|
|
|
Reaction |
R_PI4P5K_18_0_18_2 R_PI4P5K_18_0_18_2
|
PI4P5K 18 0 18 2
[0.0
1000.0]
(200576 or 23396 or 8394 or 8395 or 8396 or 5305 or 79837) |
➞ |
M_atp_c + M_pail45p_hs_18_0_18_2_c ➞ M_adp_c + M_h_c + M_pail345p_hs_18_0_18_2_c |
|
|
|
|
|
Reaction |
R_CEPTC_18_1_18_1 R_CEPTC_18_1_18_1
|
Choline phosphotransferase (C18:1, C18:1)
[0.0
1000.0]
(56994 or 10390) |
➞ |
M_cdpchol_c + M_dag_hs_18_1_18_1_c ➞ M_cmp_c + M_h_c + M_pchol_hs_18_1_18_1_c |
|
|
|
|
|
Reaction |
R_CEPTE_18_1_20_4 R_CEPTE_18_1_20_4
|
CEPTE 18 1 20 4
[0.0
1000.0]
10390 |
➞ |
M_cdpea_c + M_dag_hs_18_1_20_4_c ➞ M_cmp_c + M_h_c + M_pe_hs_18_1_20_4_c |
|
|
|
|
|
Reaction |
R_PSSA1_hs_18_1_18_1 R_PSSA1_hs_18_1_18_1
|
PSSA1 hs 18 1 18 1
[-1000.0
1000.0]
9791 |
⇆ |
M_chol_c + M_ps_hs_18_1_18_1_c ⇆ M_pchol_hs_18_1_18_1_c + M_ser__L_c |
|
|
|
|
|
Reaction |
R_PSSA2_hs_18_1_18_1 R_PSSA2_hs_18_1_18_1
|
PSSA2 hs 18 1 18 1
[-1000.0
1000.0]
81490 |
⇆ |
M_pe_hs_18_1_18_1_c + M_ser__L_c ⇆ M_etha_c + M_ps_hs_18_1_18_1_c |
|
|
|
|
|
Reaction |
R_PI34P5K_18_0_18_2 R_PI34P5K_18_0_18_2
|
PI34P5K 18 0 18 2
[0.0
1000.0]
(8394 or 8395 or 23396) |
➞ |
M_atp_c + M_pail34p_hs_18_0_18_2_c ➞ M_adp_c + M_h_c + M_pail345p_hs_18_0_18_2_c |
|
|
|
|
|
Reaction |
R_CEPTE_18_1_18_1 R_CEPTE_18_1_18_1
|
Ethanolamine phosphotransferase (C18:1,C18:1)
[0.0
1000.0]
10390 |
➞ |
M_cdpea_c + M_dag_hs_18_1_18_1_c ➞ M_cmp_c + M_h_c + M_pe_hs_18_1_18_1_c |
|
|
|
|
|
Reaction |
R_PPAP_18_1_18_1 R_PPAP_18_1_18_1
|
Phosphatidic acid phosphatase (C18:1,C18:1)
[0.0
1000.0]
(8611 or 8612 or 8613) |
➞ |
M_h2o_c + M_pa_hs_18_1_18_1_c ➞ M_dag_hs_18_1_18_1_c + M_pi_c |
|
|
|
|
|
Reaction |
R_PI4P3K_18_0_18_2 R_PI4P3K_18_0_18_2
|
PI4P3K 18 0 18 2
[0.0
1000.0]
(5286 or 5287 or 5288 or 5290 or 5291 or 5293 or 5294 or 23533 or 5296 or 10870 or 8503 or 5295) |
➞ |
M_atp_c + M_pail4p_hs_18_0_18_2_c ➞ M_adp_c + M_h_c + M_pail34p_hs_18_0_18_2_c |
|
|
|
|
|
Reaction |
R_AGPAT1_18_1_18_1 R_AGPAT1_18_1_18_1
|
AGPAT1 18 1 18 1
[0.0
1000.0]
(137964 or 56894 or 10554 or 10555 or 55326 or 56895) |
➞ |
M_alpha_hs_18_1_c + M_odecoa_c ➞ M_coa_c + M_pa_hs_18_1_18_1_c |
|
|
|
|
|
Reaction |
R_PI45PLC_18_0_20_4 R_PI45PLC_18_0_20_4
|
PI45PLC 18 0 20 4
[0.0
1000.0]
(113026 or 23236 or 84812 or 9651 or 257068 or 89869 or 5330 or 5331 or 5332 or 5333 or 5334 or 5335 or 5336 or 51196 or 23007) |
➞ |
M_h2o_c + M_pail45p_hs_18_0_20_4_c ➞ M_dag_hs_18_0_20_4_c + M_h_c + M_mi145p_c |
|
|
|
|
|
Reaction |
R_PI345P3P_18_0_20_4 R_PI345P3P_18_0_20_4
|
PI345P3P 18 0 20 4
[0.0
1000.0]
5728 |
➞ |
M_h2o_c + M_pail345p_hs_18_0_20_4_c ➞ M_pail45p_hs_18_0_20_4_c + M_pi_c |
|
|
|
|
|
Reaction |
R_PI4PLC_18_0_18_2 R_PI4PLC_18_0_18_2
|
PI4PLC 18 0 18 2
[0.0
1000.0]
(113026 or 23236 or 84812 or 9651 or 257068 or 89869 or 5330 or 5331 or 5332 or 5333 or 5334 or 5335 or 5336 or 51196 or 23007) |
➞ |
M_h2o_c + M_pail4p_hs_18_0_18_2_c ➞ M_dag_hs_18_0_18_2_c + M_h_c + M_mi14p_c |
|
|
|
|
|
Reaction |
R_CDIPTr_16_0_20_4 R_CDIPTr_16_0_20_4
|
CDIPTr 16 0 20 4
[0.0
1000.0]
10423 |
➞ |
M_cdpdag_hs_16_0_20_4_c + M_inost_c ➞ M_cmp_c + M_h_c + M_pail_hs_16_0_20_4_c |
|
|
|
|
|
Reaction |
R_PI4PLC_18_0_18_1 R_PI4PLC_18_0_18_1
|
PI4PLC 18 0 18 1
[0.0
1000.0]
(113026 or 23236 or 84812 or 9651 or 257068 or 89869 or 5330 or 5331 or 5332 or 5333 or 5334 or 5335 or 5336 or 51196 or 23007) |
➞ |
M_h2o_c + M_pail4p_hs_18_0_18_1_c ➞ M_dag_hs_18_0_18_1_c + M_h_c + M_mi14p_c |
|
|
|
|
|
Reaction |
R_PIK4_18_0_18_1 R_PIK4_18_0_18_1
|
PIK4 18 0 18 1
[0.0
1000.0]
(5297 or 5298 or 55361) |
➞ |
M_atp_c + M_pail_hs_18_0_18_1_c ➞ M_adp_c + M_h_c + M_pail4p_hs_18_0_18_1_c |
|
|
|
|
|
Reaction |
R_PIPLC_18_0_18_1 R_PIPLC_18_0_18_1
|
PIPLC 18 0 18 1
[0.0
1000.0]
(113026 or 23236 or 84812 or 257068 or 9651 or 89869 or 5330 or 5331 or 5332 or 5333 or 5334 or 5335 or 5336 or 51196 or 23007) |
➞ |
M_h2o_c + M_pail_hs_18_0_18_1_c ➞ M_dag_hs_18_0_18_1_c + M_h_c + M_mi1p__D_c |
|
|
|
|
|
Reaction |
R_PIK4_18_0_18_2 R_PIK4_18_0_18_2
|
PIK4 18 0 18 2
[0.0
1000.0]
(5297 or 5298 or 55361) |
➞ |
M_atp_c + M_pail_hs_18_0_18_2_c ➞ M_adp_c + M_h_c + M_pail4p_hs_18_0_18_2_c |
|
|
|
|
|
Reaction |
R_CDIPTr_18_0_18_1 R_CDIPTr_18_0_18_1
|
CDIPTr 18 0 18 1
[0.0
1000.0]
10423 |
➞ |
M_cdpdag_hs_18_0_18_1_c + M_inost_c ➞ M_cmp_c + M_h_c + M_pail_hs_18_0_18_1_c |
|
|
|
|
|
Reaction |
R_CDS_18_0_18_1 R_CDS_18_0_18_1
|
CDS 18 0 18 1
[0.0
1000.0]
1040 |
➞ |
M_ctp_c + M_h_c + M_pa_hs_18_0_18_1_c ➞ M_cdpdag_hs_18_0_18_1_c + M_ppi_c |
|
|
|
|
|
Reaction |
R_DAGK_hs_16_0_20_4 R_DAGK_hs_16_0_20_4
|
DAGK hs 16 0 20 4
[-1000.0
1000.0]
(1606 or 1607 or 1608 or 1609 or 9162 or 8525 or 8526 or 8527 or 160851) |
⇆ |
M_adp_c + M_h_c + M_pa_hs_16_0_20_4_c ⇆ M_atp_c + M_dag_hs_16_0_20_4_c |
|
|
|
|
|
Reaction |
R_PLA2_2_16_0_20_4 R_PLA2_2_16_0_20_4
|
PLA2 2 16 0 20 4
[0.0
1000.0]
(5320 or 8398) |
➞ |
M_h2o_c + M_pchol_hs_16_0_20_4_c ➞ M_arachd_c + M_h_c + M_lpchol_hs_16_0_c |
|
|
|
|
|
Reaction |
R_LPS2_18_0_18_1 R_LPS2_18_0_18_1
|
LPS2 18 0 18 1
[0.0
1000.0]
4023 |
➞ |
M_dag_hs_18_0_18_1_c + M_h2o_c ➞ M_h_c + M_mag_hs_18_0_c + M_ocdcea_c |
|
|
|
|
|
Reaction |
R_PIPLC_18_0_18_2 R_PIPLC_18_0_18_2
|
PIPLC 18 0 18 2
[0.0
1000.0]
(113026 or 23236 or 84812 or 257068 or 9651 or 89869 or 5330 or 5331 or 5332 or 5333 or 5334 or 5335 or 5336 or 51196 or 23007) |
➞ |
M_h2o_c + M_pail_hs_18_0_18_2_c ➞ M_dag_hs_18_0_18_2_c + M_h_c + M_mi1p__D_c |
|
|
|
|
|
Reaction |
R_DAGK_hs_18_0_18_1 R_DAGK_hs_18_0_18_1
|
DAGK hs 18 0 18 1
[-1000.0
1000.0]
(1606 or 1607 or 1608 or 1609 or 9162 or 8525 or 8526 or 8527 or 160851) |
⇆ |
M_adp_c + M_h_c + M_pa_hs_18_0_18_1_c ⇆ M_atp_c + M_dag_hs_18_0_18_1_c |
|
|
|
|
|
Reaction |
R_CEPTC_16_0_20_4 R_CEPTC_16_0_20_4
|
CEPTC 16 0 20 4
[0.0
1000.0]
(56994 or 10390) |
➞ |
M_cdpchol_c + M_dag_hs_16_0_20_4_c ➞ M_cmp_c + M_h_c + M_pchol_hs_16_0_20_4_c |
|
|
|
|
|
Reaction |
R_PSSA1_hs_16_0_20_4 R_PSSA1_hs_16_0_20_4
|
PSSA1 hs 16 0 20 4
[-1000.0
1000.0]
9791 |
⇆ |
M_chol_c + M_ps_hs_16_0_20_4_c ⇆ M_pchol_hs_16_0_20_4_c + M_ser__L_c |
|
|
|
|
|
Reaction |
R_PLA2_2_18_0_18_1 R_PLA2_2_18_0_18_1
|
PLA2 2 18 0 18 1
[0.0
1000.0]
(5320 or 8398) |
➞ |
M_h2o_c + M_pchol_hs_18_0_18_1_c ➞ M_h_c + M_lpchol_hs_18_0_c + M_ocdcea_c |
|
|
|
|
|
Reaction |
R_CDIPTr_18_0_18_2 R_CDIPTr_18_0_18_2
|
CDIPTr 18 0 18 2
[0.0
1000.0]
10423 |
➞ |
M_cdpdag_hs_18_0_18_2_c + M_inost_c ➞ M_cmp_c + M_h_c + M_pail_hs_18_0_18_2_c |
|
|
|
|
|
Reaction |
R_CEPTC_18_0_18_1 R_CEPTC_18_0_18_1
|
CEPTC 18 0 18 1
[0.0
1000.0]
(56994 or 10390) |
➞ |
M_cdpchol_c + M_dag_hs_18_0_18_1_c ➞ M_cmp_c + M_h_c + M_pchol_hs_18_0_18_1_c |
|
|
|
|
|
Reaction |
R_PSSA2_hs_16_0_20_4 R_PSSA2_hs_16_0_20_4
|
PSSA2 hs 16 0 20 4
[-1000.0
1000.0]
81490 |
⇆ |
M_pe_hs_16_0_20_4_c + M_ser__L_c ⇆ M_etha_c + M_ps_hs_16_0_20_4_c |
|
|
|
|
|
Reaction |
R_CDS_18_0_18_2 R_CDS_18_0_18_2
|
CDS 18 0 18 2
[0.0
1000.0]
1040 |
➞ |
M_ctp_c + M_h_c + M_pa_hs_18_0_18_2_c ➞ M_cdpdag_hs_18_0_18_2_c + M_ppi_c |
|
|
|
|
|
Reaction |
R_CEPTE_16_0_20_4 R_CEPTE_16_0_20_4
|
CEPTE 16 0 20 4
[0.0
1000.0]
10390 |
➞ |
M_cdpea_c + M_dag_hs_16_0_20_4_c ➞ M_cmp_c + M_h_c + M_pe_hs_16_0_20_4_c |
|
|
|
|
|
Reaction |
R_PPAP_16_0_20_4 R_PPAP_16_0_20_4
|
PPAP 16 0 20 4
[0.0
1000.0]
(8611 or 8612 or 8613) |
➞ |
M_h2o_c + M_pa_hs_16_0_20_4_c ➞ M_dag_hs_16_0_20_4_c + M_pi_c |
|
|
|
|
|
Reaction |
R_PSSA1_hs_18_0_18_1 R_PSSA1_hs_18_0_18_1
|
PSSA1 hs 18 0 18 1
[-1000.0
1000.0]
9791 |
⇆ |
M_chol_c + M_ps_hs_18_0_18_1_c ⇆ M_pchol_hs_18_0_18_1_c + M_ser__L_c |
|
|
|
|
|
Reaction |
R_PSSA2_hs_18_0_18_1 R_PSSA2_hs_18_0_18_1
|
PSSA2 hs 18 0 18 1
[-1000.0
1000.0]
81490 |
⇆ |
M_pe_hs_18_0_18_1_c + M_ser__L_c ⇆ M_etha_c + M_ps_hs_18_0_18_1_c |
|
|
|
|
|
Reaction |
R_CEPTE_18_0_18_1 R_CEPTE_18_0_18_1
|
CEPTE 18 0 18 1
[0.0
1000.0]
10390 |
➞ |
M_cdpea_c + M_dag_hs_18_0_18_1_c ➞ M_cmp_c + M_h_c + M_pe_hs_18_0_18_1_c |
|
|
|
|
|
Reaction |
R_AGPAT1_16_0_20_4 R_AGPAT1_16_0_20_4
|
AGPAT1 16 0 20 4
[0.0
1000.0]
(137964 or 56894 or 10554 or 10555 or 55326 or 56895) |
➞ |
M_alpha_hs_16_0_c + M_arachdcoa_c ➞ M_coa_c + M_pa_hs_16_0_20_4_c |
|
|
|
|
|
Reaction |
R_PI45PLC_16_0_18_2 R_PI45PLC_16_0_18_2
|
Phosphatidylinositol 4,5-bisphosphate phospholipase C (C16:0, C18:2)
[0.0
1000.0]
(113026 or 23236 or 84812 or 9651 or 257068 or 89869 or 5330 or 5331 or 5332 or 5333 or 5334 or 5335 or 5336 or 51196 or 23007) |
➞ |
M_h2o_c + M_pail45p_hs_16_0_18_2_c ➞ M_dag_hs_16_0_18_2_c + M_h_c + M_mi145p_c |
|
|
|
|
|
Reaction |
R_PPAP_18_0_18_1 R_PPAP_18_0_18_1
|
PPAP 18 0 18 1
[0.0
1000.0]
(8611 or 8612 or 8613) |
➞ |
M_h2o_c + M_pa_hs_18_0_18_1_c ➞ M_dag_hs_18_0_18_1_c + M_pi_c |
|
|
|
|
|
Reaction |
R_AGPAT1_18_0_18_1 R_AGPAT1_18_0_18_1
|
AGPAT1 18 0 18 1
[0.0
1000.0]
(137964 or 56894 or 10554 or 10555 or 55326 or 56895) |
➞ |
M_alpha_hs_18_0_c + M_odecoa_c ➞ M_coa_c + M_pa_hs_18_0_18_1_c |
|
|
|
|
|
Reaction |
R_PI45PLC_18_0_18_0 R_PI45PLC_18_0_18_0
|
PI45PLC 18 0 18 0
[0.0
1000.0]
(113026 or 23236 or 84812 or 9651 or 257068 or 89869 or 5330 or 5331 or 5332 or 5333 or 5334 or 5335 or 5336 or 51196 or 23007) |
➞ |
M_h2o_c + M_pail45p_hs_18_0_18_0_c ➞ M_dag_hs_18_0_18_0_c + M_h_c + M_mi145p_c |
|
|
|
|
|
Reaction |
R_PI345P3P_18_0_18_0 R_PI345P3P_18_0_18_0
|
PI345P3P 18 0 18 0
[0.0
1000.0]
5728 |
➞ |
M_h2o_c + M_pail345p_hs_18_0_18_0_c ➞ M_pail45p_hs_18_0_18_0_c + M_pi_c |
|
|
|
|
|
Reaction |
R_PI4P5K_18_0_18_0 R_PI4P5K_18_0_18_0
|
PI4P5K 18 0 18 0
[0.0
1000.0]
(200576 or 23396 or 8394 or 8395 or 8396 or 5305 or 79837) |
➞ |
M_atp_c + M_pail45p_hs_18_0_18_0_c ➞ M_adp_c + M_h_c + M_pail345p_hs_18_0_18_0_c |
|
|
|
|
|
Reaction |
R_PI345P3P_16_0_18_2 R_PI345P3P_16_0_18_2
|
PI345P3P 16 0 18 2
[0.0
1000.0]
5728 |
➞ |
M_h2o_c + M_pail345p_hs_16_0_18_2_c ➞ M_pail45p_hs_16_0_18_2_c + M_pi_c |
|
|
|
|
|
Reaction |
R_PI4P5K_16_0_18_2 R_PI4P5K_16_0_18_2
|
PI4P5K 16 0 18 2
[0.0
1000.0]
(200576 or 23396 or 8394 or 8395 or 8396 or 5305 or 79837) |
➞ |
M_atp_c + M_pail45p_hs_16_0_18_2_c ➞ M_adp_c + M_h_c + M_pail345p_hs_16_0_18_2_c |
|
|
|
|
|
Reaction |
R_PI34P5K_16_0_18_2 R_PI34P5K_16_0_18_2
|
PI34P5K 16 0 18 2
[0.0
1000.0]
(8394 or 8395 or 23396) |
➞ |
M_atp_c + M_pail34p_hs_16_0_18_2_c ➞ M_adp_c + M_h_c + M_pail345p_hs_16_0_18_2_c |
|
|
|
|
|
Reaction |
R_PI4P3K_16_0_18_2 R_PI4P3K_16_0_18_2
|
PI4P3K 16 0 18 2
[0.0
1000.0]
(5286 or 5287 or 5288 or 5290 or 5291 or 5293 or 5294 or 23533 or 5296 or 10870 or 8503 or 5295) |
➞ |
M_atp_c + M_pail4p_hs_16_0_18_2_c ➞ M_adp_c + M_h_c + M_pail34p_hs_16_0_18_2_c |
|
|
|
|
|
Reaction |
R_PI4PLC_16_0_18_2 R_PI4PLC_16_0_18_2
|
Phosphatidylinositol 4-phosphate phospholipase C (C16:0,C18:2)
[0.0
1000.0]
(113026 or 23236 or 84812 or 9651 or 257068 or 89869 or 5330 or 5331 or 5332 or 5333 or 5334 or 5335 or 5336 or 51196 or 23007) |
➞ |
M_h2o_c + M_pail4p_hs_16_0_18_2_c ➞ M_dag_hs_16_0_18_2_c + M_h_c + M_mi14p_c |
|
|
|
|
|
Reaction |
R_PIK4_16_0_18_2 R_PIK4_16_0_18_2
|
Phosphatidylinositol 4-kinase (C16:0,C18:2)
[0.0
1000.0]
(5297 or 5298 or 55361) |
➞ |
M_atp_c + M_pail_hs_16_0_18_2_c ➞ M_adp_c + M_h_c + M_pail4p_hs_16_0_18_2_c |
|
|
|
|
|
Reaction |
R_PI34P5K_18_0_18_0 R_PI34P5K_18_0_18_0
|
PI34P5K 18 0 18 0
[0.0
1000.0]
(8394 or 8395 or 23396) |
➞ |
M_atp_c + M_pail34p_hs_18_0_18_0_c ➞ M_adp_c + M_h_c + M_pail345p_hs_18_0_18_0_c |
|
|
|
|
|
Reaction |
R_PIPLC_16_0_18_2 R_PIPLC_16_0_18_2
|
Phosphatidylinositol phospholipase C (C16:0,C18:2)
[0.0
1000.0]
(113026 or 23236 or 84812 or 257068 or 9651 or 89869 or 5330 or 5331 or 5332 or 5333 or 5334 or 5335 or 5336 or 51196 or 23007) |
➞ |
M_h2o_c + M_pail_hs_16_0_18_2_c ➞ M_dag_hs_16_0_18_2_c + M_h_c + M_mi1p__D_c |
|
|
|
|
|
Reaction |
R_PI4P3K_18_0_18_0 R_PI4P3K_18_0_18_0
|
PI4P3K 18 0 18 0
[0.0
1000.0]
(5286 or 5287 or 5288 or 5290 or 5291 or 5293 or 5294 or 23533 or 5296 or 10870 or 8503 or 5295) |
➞ |
M_atp_c + M_pail4p_hs_18_0_18_0_c ➞ M_adp_c + M_h_c + M_pail34p_hs_18_0_18_0_c |
|
|
|
|
|
Reaction |
R_LPS2_18_0_18_2 R_LPS2_18_0_18_2
|
LPS2 18 0 18 2
[0.0
1000.0]
4023 |
➞ |
M_dag_hs_18_0_18_2_c + M_h2o_c ➞ M_h_c + M_lnlc_c + M_mag_hs_18_0_c |
|
|
|
|
|
Reaction |
R_PI4PLC_18_0_18_0 R_PI4PLC_18_0_18_0
|
PI4PLC 18 0 18 0
[0.0
1000.0]
(113026 or 23236 or 84812 or 9651 or 257068 or 89869 or 5330 or 5331 or 5332 or 5333 or 5334 or 5335 or 5336 or 51196 or 23007) |
➞ |
M_h2o_c + M_pail4p_hs_18_0_18_0_c ➞ M_dag_hs_18_0_18_0_c + M_h_c + M_mi14p_c |
|
|
|
|
|
Reaction |
R_PIK4_18_0_18_0 R_PIK4_18_0_18_0
|
PIK4 18 0 18 0
[0.0
1000.0]
(5297 or 5298 or 55361) |
➞ |
M_atp_c + M_pail_hs_18_0_18_0_c ➞ M_adp_c + M_h_c + M_pail4p_hs_18_0_18_0_c |
|
|
|
|
|
Reaction |
R_CDIPTr_16_0_18_2 R_CDIPTr_16_0_18_2
|
Phosphatidylinositol synthase (Homo sapiens, C16:0, C18:2)
[0.0
1000.0]
10423 |
➞ |
M_cdpdag_hs_16_0_18_2_c + M_inost_c ➞ M_cmp_c + M_h_c + M_pail_hs_16_0_18_2_c |
|
|
|
|
|
Reaction |
R_CDS_16_0_18_2 R_CDS_16_0_18_2
|
Phosphatidate cytidylyltransferase (C16:0, C18:2)
[0.0
1000.0]
1040 |
➞ |
M_ctp_c + M_h_c + M_pa_hs_16_0_18_2_c ➞ M_cdpdag_hs_16_0_18_2_c + M_ppi_c |
|
|
|
|
|
Reaction |
R_LPS2_16_0_18_2 R_LPS2_16_0_18_2
|
LPS2 16 0 18 2
[0.0
1000.0]
4023 |
➞ |
M_dag_hs_16_0_18_2_c + M_h2o_c ➞ M_h_c + M_lnlc_c + M_mag_hs_16_0_c |
|
|
|
|
|
Reaction |
R_DAGK_hs_18_0_18_2 R_DAGK_hs_18_0_18_2
|
DAGK hs 18 0 18 2
[-1000.0
1000.0]
(1606 or 1607 or 1608 or 1609 or 9162 or 8525 or 8526 or 8527 or 160851) |
⇆ |
M_adp_c + M_h_c + M_pa_hs_18_0_18_2_c ⇆ M_atp_c + M_dag_hs_18_0_18_2_c |
|
|
|
|
|
Reaction |
R_DAGK_hs_16_0_18_2 R_DAGK_hs_16_0_18_2
|
Diacylglycerol phosphate kinase (homo sapiens, C16:0, C18:2)
[-1000.0
1000.0]
(1606 or 1607 or 1608 or 1609 or 9162 or 8525 or 8526 or 8527 or 160851) |
⇆ |
M_adp_c + M_h_c + M_pa_hs_16_0_18_2_c ⇆ M_atp_c + M_dag_hs_16_0_18_2_c |
|
|
|
|
|
Reaction |
R_PIPLC_18_0_18_0 R_PIPLC_18_0_18_0
|
PIPLC 18 0 18 0
[0.0
1000.0]
(113026 or 23236 or 84812 or 257068 or 9651 or 89869 or 5330 or 5331 or 5332 or 5333 or 5334 or 5335 or 5336 or 51196 or 23007) |
➞ |
M_h2o_c + M_pail_hs_18_0_18_0_c ➞ M_dag_hs_18_0_18_0_c + M_h_c + M_mi1p__D_c |
|
|
|
|
|
Reaction |
R_CDIPTr_18_0_18_0 R_CDIPTr_18_0_18_0
|
CDIPTr 18 0 18 0
[0.0
1000.0]
10423 |
➞ |
M_cdpdag_hs_18_0_18_0_c + M_inost_c ➞ M_cmp_c + M_h_c + M_pail_hs_18_0_18_0_c |
|
|
|
|
|
Reaction |
R_PLA2_2_16_0_18_2 R_PLA2_2_16_0_18_2
|
Phospholipase A2 (C16:0,C18:2)
[0.0
1000.0]
(5320 or 8398) |
➞ |
M_h2o_c + M_pchol_hs_16_0_18_2_c ➞ M_h_c + M_lnlc_c + M_lpchol_hs_16_0_c |
|
|
|
|
|
Reaction |
R_PLA2_2_18_0_18_2 R_PLA2_2_18_0_18_2
|
PLA2 2 18 0 18 2
[0.0
1000.0]
(5320 or 8398) |
➞ |
M_h2o_c + M_pchol_hs_18_0_18_2_c ➞ M_h_c + M_lnlc_c + M_lpchol_hs_18_0_c |
|
|
|
|
|
Reaction |
R_CEPTC_16_0_18_2 R_CEPTC_16_0_18_2
|
Choline phosphotransferase (C16:0, C18:2)
[0.0
1000.0]
(56994 or 10390) |
➞ |
M_cdpchol_c + M_dag_hs_16_0_18_2_c ➞ M_cmp_c + M_h_c + M_pchol_hs_16_0_18_2_c |
|
|
|
|
|
Reaction |
R_PSSA1_hs_16_0_18_2 R_PSSA1_hs_16_0_18_2
|
PSSA1 hs 16 0 18 2
[-1000.0
1000.0]
9791 |
⇆ |
M_chol_c + M_ps_hs_16_0_18_2_c ⇆ M_pchol_hs_16_0_18_2_c + M_ser__L_c |
|
|
|
|
|
Reaction |
R_PSSA2_hs_16_0_18_2 R_PSSA2_hs_16_0_18_2
|
PSSA2 hs 16 0 18 2
[-1000.0
1000.0]
81490 |
⇆ |
M_pe_hs_16_0_18_2_c + M_ser__L_c ⇆ M_etha_c + M_ps_hs_16_0_18_2_c |
|
|
|
|
|
Reaction |
R_CEPTE_16_0_18_2 R_CEPTE_16_0_18_2
|
Ethanolamine phosphotransferase (C16:0,C18:2)
[0.0
1000.0]
10390 |
➞ |
M_cdpea_c + M_dag_hs_16_0_18_2_c ➞ M_cmp_c + M_h_c + M_pe_hs_16_0_18_2_c |
|
|
|
|
|
Reaction |
R_PPAP_16_0_18_2 R_PPAP_16_0_18_2
|
Phosphatidic acid phosphatase (C16:0, C18:2)
[0.0
1000.0]
(8611 or 8612 or 8613) |
➞ |
M_h2o_c + M_pa_hs_16_0_18_2_c ➞ M_dag_hs_16_0_18_2_c + M_pi_c |
|
|
|
|
|
Reaction |
R_CDS_18_0_18_0 R_CDS_18_0_18_0
|
CDS 18 0 18 0
[0.0
1000.0]
1040 |
➞ |
M_ctp_c + M_h_c + M_pa_hs_18_0_18_0_c ➞ M_cdpdag_hs_18_0_18_0_c + M_ppi_c |
|
|
|
|
|
Reaction |
R_LPS2_18_0_18_0 R_LPS2_18_0_18_0
|
LPS2 18 0 18 0
[0.0
1000.0]
4023 |
➞ |
M_dag_hs_18_0_18_0_c + M_h2o_c ➞ M_h_c + M_mag_hs_18_0_c + M_ocdca_c |
|
|
|
|
|
Reaction |
R_DAGK_hs_18_0_18_0 R_DAGK_hs_18_0_18_0
|
DAGK hs 18 0 18 0
[-1000.0
1000.0]
(1606 or 1607 or 1608 or 1609 or 9162 or 8525 or 8526 or 8527 or 160851) |
⇆ |
M_adp_c + M_h_c + M_pa_hs_18_0_18_0_c ⇆ M_atp_c + M_dag_hs_18_0_18_0_c |
|
|
|
|
|
Reaction |
R_PLA2_2_18_0_18_0 R_PLA2_2_18_0_18_0
|
PLA2 2 18 0 18 0
[0.0
1000.0]
(5320 or 8398) |
➞ |
M_h2o_c + M_pchol_hs_18_0_18_0_c ➞ M_h_c + M_lpchol_hs_18_0_c + M_ocdca_c |
|
|
|
|
|
Reaction |
R_CEPTC_18_0_18_0 R_CEPTC_18_0_18_0
|
CEPTC 18 0 18 0
[0.0
1000.0]
(56994 or 10390) |
➞ |
M_cdpchol_c + M_dag_hs_18_0_18_0_c ➞ M_cmp_c + M_h_c + M_pchol_hs_18_0_18_0_c |
|
|
|
|
|
Reaction |
R_PSSA1_hs_18_0_18_0 R_PSSA1_hs_18_0_18_0
|
PSSA1 hs 18 0 18 0
[-1000.0
1000.0]
9791 |
⇆ |
M_chol_c + M_ps_hs_18_0_18_0_c ⇆ M_pchol_hs_18_0_18_0_c + M_ser__L_c |
|
|
|
|
|
Reaction |
R_PSSA2_hs_18_0_18_0 R_PSSA2_hs_18_0_18_0
|
PSSA2 hs 18 0 18 0
[-1000.0
1000.0]
81490 |
⇆ |
M_pe_hs_18_0_18_0_c + M_ser__L_c ⇆ M_etha_c + M_ps_hs_18_0_18_0_c |
|
|
|
|
|
Reaction |
R_AGPAT1_16_0_18_2 R_AGPAT1_16_0_18_2
|
AGPAT1 16 0 18 2
[0.0
1000.0]
(137964 or 56894 or 10554 or 10555 or 55326 or 56895) |
➞ |
M_alpha_hs_16_0_c + M_lnlccoa_c ➞ M_coa_c + M_pa_hs_16_0_18_2_c |
|
|
|
|
|
Reaction |
R_PI45PLC_16_0_18_1 R_PI45PLC_16_0_18_1
|
Phosphatidylinositol 4,5-bisphosphate phospholipase C (C16:0, C18:1)
[0.0
1000.0]
(113026 or 23236 or 84812 or 9651 or 257068 or 89869 or 5330 or 5331 or 5332 or 5333 or 5334 or 5335 or 5336 or 51196 or 23007) |
➞ |
M_h2o_c + M_pail45p_hs_16_0_18_1_c ➞ M_dag_hs_16_0_18_1_c + M_h_c + M_mi145p_c |
|
|
|
|
|
Reaction |
R_PI345P3P_16_0_18_1 R_PI345P3P_16_0_18_1
|
PI345P3P 16 0 18 1
[0.0
1000.0]
5728 |
➞ |
M_h2o_c + M_pail345p_hs_16_0_18_1_c ➞ M_pail45p_hs_16_0_18_1_c + M_pi_c |
|
|
|
|
|
Reaction |
R_PI4P5K_16_0_18_1 R_PI4P5K_16_0_18_1
|
PI4P5K 16 0 18 1
[0.0
1000.0]
(200576 or 23396 or 8394 or 8395 or 8396 or 5305 or 79837) |
➞ |
M_atp_c + M_pail45p_hs_16_0_18_1_c ➞ M_adp_c + M_h_c + M_pail345p_hs_16_0_18_1_c |
|
|
|
|
|
Reaction |
R_CEPTE_18_0_18_0 R_CEPTE_18_0_18_0
|
CEPTE 18 0 18 0
[0.0
1000.0]
10390 |
➞ |
M_cdpea_c + M_dag_hs_18_0_18_0_c ➞ M_cmp_c + M_h_c + M_pe_hs_18_0_18_0_c |
|
|
|
|
|
Reaction |
R_PPAP_18_0_18_0 R_PPAP_18_0_18_0
|
PPAP 18 0 18 0
[0.0
1000.0]
(8611 or 8612 or 8613) |
➞ |
M_h2o_c + M_pa_hs_18_0_18_0_c ➞ M_dag_hs_18_0_18_0_c + M_pi_c |
|
|
|
|
|
Reaction |
R_PI34P5K_16_0_18_1 R_PI34P5K_16_0_18_1
|
PI34P5K 16 0 18 1
[0.0
1000.0]
(8394 or 8395 or 23396) |
➞ |
M_atp_c + M_pail34p_hs_16_0_18_1_c ➞ M_adp_c + M_h_c + M_pail345p_hs_16_0_18_1_c |
|
|
|
|
|
Reaction |
R_CEPTC_18_0_18_2 R_CEPTC_18_0_18_2
|
CEPTC 18 0 18 2
[0.0
1000.0]
(56994 or 10390) |
➞ |
M_cdpchol_c + M_dag_hs_18_0_18_2_c ➞ M_cmp_c + M_h_c + M_pchol_hs_18_0_18_2_c |
|
|
|
|
|
Reaction |
R_PI4P3K_16_0_18_1 R_PI4P3K_16_0_18_1
|
PI4P3K 16 0 18 1
[0.0
1000.0]
(5286 or 5287 or 5288 or 5290 or 5291 or 5293 or 5294 or 23533 or 5296 or 10870 or 8503 or 5295) |
➞ |
M_atp_c + M_pail4p_hs_16_0_18_1_c ➞ M_adp_c + M_h_c + M_pail34p_hs_16_0_18_1_c |
|
|
|
|
|
Reaction |
R_AGPAT1_18_0_18_0 R_AGPAT1_18_0_18_0
|
AGPAT1 18 0 18 0
[0.0
1000.0]
(137964 or 56894 or 10554 or 10555 or 55326 or 56895) |
➞ |
M_alpha_hs_18_0_c + M_stcoa_c ➞ M_coa_c + M_pa_hs_18_0_18_0_c |
|
|
|
|
|
Reaction |
R_PI45PLC_16_0_20_4 R_PI45PLC_16_0_20_4
|
PI45PLC 16 0 20 4
[0.0
1000.0]
(113026 or 23236 or 84812 or 9651 or 257068 or 89869 or 5330 or 5331 or 5332 or 5333 or 5334 or 5335 or 5336 or 51196 or 23007) |
➞ |
M_h2o_c + M_pail45p_hs_16_0_20_4_c ➞ M_dag_hs_16_0_20_4_c + M_h_c + M_mi145p_c |
|
|
|
|
|
Reaction |
R_PI345P3P_16_0_20_4 R_PI345P3P_16_0_20_4
|
PI345P3P 16 0 20 4
[0.0
1000.0]
5728 |
➞ |
M_h2o_c + M_pail345p_hs_16_0_20_4_c ➞ M_pail45p_hs_16_0_20_4_c + M_pi_c |
|
|
|
|
|
Reaction |
R_PSSA1_hs_18_0_18_2 R_PSSA1_hs_18_0_18_2
|
PSSA1 hs 18 0 18 2
[-1000.0
1000.0]
9791 |
⇆ |
M_chol_c + M_ps_hs_18_0_18_2_c ⇆ M_pchol_hs_18_0_18_2_c + M_ser__L_c |
|
|
|
|
|
Reaction |
R_PI4P5K_16_0_20_4 R_PI4P5K_16_0_20_4
|
PI4P5K 16 0 20 4
[0.0
1000.0]
(200576 or 23396 or 8394 or 8395 or 8396 or 5305 or 79837) |
➞ |
M_atp_c + M_pail45p_hs_16_0_20_4_c ➞ M_adp_c + M_h_c + M_pail345p_hs_16_0_20_4_c |
|
|
|
|
|
Reaction |
R_PI34P5K_16_0_20_4 R_PI34P5K_16_0_20_4
|
PI34P5K 16 0 20 4
[0.0
1000.0]
(8394 or 8395 or 23396) |
➞ |
M_atp_c + M_pail34p_hs_16_0_20_4_c ➞ M_adp_c + M_h_c + M_pail345p_hs_16_0_20_4_c |
|
|
|
|
|
Reaction |
R_PI4PLC_16_0_18_1 R_PI4PLC_16_0_18_1
|
Phosphatidylinositol 4-phosphate phospholipase C (C16:0,C18:1)
[0.0
1000.0]
(113026 or 23236 or 84812 or 9651 or 257068 or 89869 or 5330 or 5331 or 5332 or 5333 or 5334 or 5335 or 5336 or 51196 or 23007) |
➞ |
M_h2o_c + M_pail4p_hs_16_0_18_1_c ➞ M_dag_hs_16_0_18_1_c + M_h_c + M_mi14p_c |
|
|
|
|
|
Reaction |
R_PIK4_16_0_18_1 R_PIK4_16_0_18_1
|
Phosphatidylinositol 4-kinase (C16:0,C18:1)
[0.0
1000.0]
(5297 or 5298 or 55361) |
➞ |
M_atp_c + M_pail_hs_16_0_18_1_c ➞ M_adp_c + M_h_c + M_pail4p_hs_16_0_18_1_c |
|
|
|
|
|
Reaction |
R_PIPLC_16_0_18_1 R_PIPLC_16_0_18_1
|
Phosphatidylinositol phospholipase C (C16:0,C18:1)
[0.0
1000.0]
(113026 or 23236 or 84812 or 257068 or 9651 or 89869 or 5330 or 5331 or 5332 or 5333 or 5334 or 5335 or 5336 or 51196 or 23007) |
➞ |
M_h2o_c + M_pail_hs_16_0_18_1_c ➞ M_dag_hs_16_0_18_1_c + M_h_c + M_mi1p__D_c |
|
|
|
|
|
Reaction |
R_CDIPTr_16_0_18_1 R_CDIPTr_16_0_18_1
|
Phosphatidylinositol synthase (Homo sapiens, C16:0, C18:1)
[0.0
1000.0]
10423 |
➞ |
M_cdpdag_hs_16_0_18_1_c + M_inost_c ➞ M_cmp_c + M_h_c + M_pail_hs_16_0_18_1_c |
|
|
|
|
|
Reaction |
R_CDS_16_0_18_1 R_CDS_16_0_18_1
|
Phosphatidate cytidylyltransferase (C16:0, C18:1)
[0.0
1000.0]
1040 |
➞ |
M_ctp_c + M_h_c + M_pa_hs_16_0_18_1_c ➞ M_cdpdag_hs_16_0_18_1_c + M_ppi_c |
|
|
|
|
|
Reaction |
R_LPS2_16_0_18_1 R_LPS2_16_0_18_1
|
LPS2 16 0 18 1
[0.0
1000.0]
4023 |
➞ |
M_dag_hs_16_0_18_1_c + M_h2o_c ➞ M_h_c + M_mag_hs_16_0_c + M_ocdcea_c |
|
|
|
|
|
Reaction |
R_PI4P3K_16_0_20_4 R_PI4P3K_16_0_20_4
|
PI4P3K 16 0 20 4
[0.0
1000.0]
(5286 or 5287 or 5288 or 5290 or 5291 or 5293 or 5294 or 23533 or 5296 or 10870 or 8503 or 5295) |
➞ |
M_atp_c + M_pail4p_hs_16_0_20_4_c ➞ M_adp_c + M_h_c + M_pail34p_hs_16_0_20_4_c |
|
|
|
|
|
Reaction |
R_PI4PLC_16_0_20_4 R_PI4PLC_16_0_20_4
|
PI4PLC 16 0 20 4
[0.0
1000.0]
(113026 or 23236 or 84812 or 9651 or 257068 or 89869 or 5330 or 5331 or 5332 or 5333 or 5334 or 5335 or 5336 or 51196 or 23007) |
➞ |
M_h2o_c + M_pail4p_hs_16_0_20_4_c ➞ M_dag_hs_16_0_20_4_c + M_h_c + M_mi14p_c |
|
|
|
|
|
Reaction |
R_PIK4_16_0_20_4 R_PIK4_16_0_20_4
|
PIK4 16 0 20 4
[0.0
1000.0]
(5297 or 5298 or 55361) |
➞ |
M_atp_c + M_pail_hs_16_0_20_4_c ➞ M_adp_c + M_h_c + M_pail4p_hs_16_0_20_4_c |
|
|
|
|
|
Reaction |
R_PIPLC_16_0_20_4 R_PIPLC_16_0_20_4
|
PIPLC 16 0 20 4
[0.0
1000.0]
(113026 or 23236 or 84812 or 257068 or 9651 or 89869 or 5330 or 5331 or 5332 or 5333 or 5334 or 5335 or 5336 or 51196 or 23007) |
➞ |
M_h2o_c + M_pail_hs_16_0_20_4_c ➞ M_dag_hs_16_0_20_4_c + M_h_c + M_mi1p__D_c |
|
|
|
|
|
Reaction |
R_DAGK_hs_16_0_18_1 R_DAGK_hs_16_0_18_1
|
Diacylglycerol phosphate kinase (homo sapiens, C16:0, C18:1)
[-1000.0
1000.0]
(1606 or 1607 or 1608 or 1609 or 9162 or 8525 or 8526 or 8527 or 160851) |
⇆ |
M_adp_c + M_h_c + M_pa_hs_16_0_18_1_c ⇆ M_atp_c + M_dag_hs_16_0_18_1_c |
|
|
|
|
|
Reaction |
R_PLA2_2_16_0_18_1 R_PLA2_2_16_0_18_1
|
Phospholipase A2 (C16:0,C18:1)
[0.0
1000.0]
(5320 or 8398) |
➞ |
M_h2o_c + M_pchol_hs_16_0_18_1_c ➞ M_h_c + M_lpchol_hs_16_0_c + M_ocdcea_c |
|
|
|
|
|
Reaction |
R_PSSA2_hs_18_0_18_2 R_PSSA2_hs_18_0_18_2
|
PSSA2 hs 18 0 18 2
[-1000.0
1000.0]
81490 |
⇆ |
M_pe_hs_18_0_18_2_c + M_ser__L_c ⇆ M_etha_c + M_ps_hs_18_0_18_2_c |
|
|
|
|
|
Reaction |
R_CEPTC_16_0_18_1 R_CEPTC_16_0_18_1
|
Choline phosphotransferase (C16:0, C18:1)
[0.0
1000.0]
(56994 or 10390) |
➞ |
M_cdpchol_c + M_dag_hs_16_0_18_1_c ➞ M_cmp_c + M_h_c + M_pchol_hs_16_0_18_1_c |
|
|
|
|
|
Reaction |
R_PSSA1_hs_16_0_18_1 R_PSSA1_hs_16_0_18_1
|
PSSA1 hs 16 0 18 1
[-1000.0
1000.0]
9791 |
⇆ |
M_chol_c + M_ps_hs_16_0_18_1_c ⇆ M_pchol_hs_16_0_18_1_c + M_ser__L_c |
|
|
|
|
|
Reaction |
R_PPAP_16_0_18_1 R_PPAP_16_0_18_1
|
Phosphatidic acid phosphatase (C16:0, C18:1)
[0.0
1000.0]
(8611 or 8612 or 8613) |
➞ |
M_h2o_c + M_pa_hs_16_0_18_1_c ➞ M_dag_hs_16_0_18_1_c + M_pi_c |
|
|
|
|
|
Reaction |
R_CEPTE_18_0_18_2 R_CEPTE_18_0_18_2
|
CEPTE 18 0 18 2
[0.0
1000.0]
10390 |
➞ |
M_cdpea_c + M_dag_hs_18_0_18_2_c ➞ M_cmp_c + M_h_c + M_pe_hs_18_0_18_2_c |
|
|
|
|
|
Reaction |
R_AGPAT1_16_0_18_1 R_AGPAT1_16_0_18_1
|
AGPAT1 16 0 18 1
[0.0
1000.0]
(137964 or 56894 or 10554 or 10555 or 55326 or 56895) |
➞ |
M_alpha_hs_16_0_c + M_odecoa_c ➞ M_coa_c + M_pa_hs_16_0_18_1_c |
|
|
|
|
|
Reaction |
R_PI45PLC_16_0_18_0 R_PI45PLC_16_0_18_0
|
PI45PLC 16 0 18 0
[0.0
1000.0]
(113026 or 23236 or 84812 or 9651 or 257068 or 89869 or 5330 or 5331 or 5332 or 5333 or 5334 or 5335 or 5336 or 51196 or 23007) |
➞ |
M_h2o_c + M_pail45p_hs_16_0_18_0_c ➞ M_dag_hs_16_0_18_0_c + M_h_c + M_mi145p_c |
|
|
|
|
|
Reaction |
R_PSSA2_hs_16_0_18_1 R_PSSA2_hs_16_0_18_1
|
PSSA2 hs 16 0 18 1
[-1000.0
1000.0]
81490 |
⇆ |
M_pe_hs_16_0_18_1_c + M_ser__L_c ⇆ M_etha_c + M_ps_hs_16_0_18_1_c |
|
|
|
|
|
Reaction |
R_CEPTE_16_0_18_1 R_CEPTE_16_0_18_1
|
Ethanolamine phosphotransferase (C16:0,C18:1)
[0.0
1000.0]
10390 |
➞ |
M_cdpea_c + M_dag_hs_16_0_18_1_c ➞ M_cmp_c + M_h_c + M_pe_hs_16_0_18_1_c |
|
|
|
|
|
Reaction |
R_PI345P3P_16_0_18_0 R_PI345P3P_16_0_18_0
|
PI345P3P 16 0 18 0
[0.0
1000.0]
5728 |
➞ |
M_h2o_c + M_pail345p_hs_16_0_18_0_c ➞ M_pail45p_hs_16_0_18_0_c + M_pi_c |
|
|
|
|
|
Reaction |
R_PPAP_18_0_18_2 R_PPAP_18_0_18_2
|
PPAP 18 0 18 2
[0.0
1000.0]
(8611 or 8612 or 8613) |
➞ |
M_h2o_c + M_pa_hs_18_0_18_2_c ➞ M_dag_hs_18_0_18_2_c + M_pi_c |
|
|
|
|
|
Reaction |
R_PI4P5K_16_0_18_0 R_PI4P5K_16_0_18_0
|
PI4P5K 16 0 18 0
[0.0
1000.0]
(200576 or 23396 or 8394 or 8395 or 8396 or 5305 or 79837) |
➞ |
M_atp_c + M_pail45p_hs_16_0_18_0_c ➞ M_adp_c + M_h_c + M_pail345p_hs_16_0_18_0_c |
|
|
|
|
|
Reaction |
R_PI34P5K_16_0_18_0 R_PI34P5K_16_0_18_0
|
PI34P5K 16 0 18 0
[0.0
1000.0]
(8394 or 8395 or 23396) |
➞ |
M_atp_c + M_pail34p_hs_16_0_18_0_c ➞ M_adp_c + M_h_c + M_pail345p_hs_16_0_18_0_c |
|
|
|
|
|
Reaction |
R_PI4P3K_16_0_18_0 R_PI4P3K_16_0_18_0
|
PI4P3K 16 0 18 0
[0.0
1000.0]
(5286 or 5287 or 5288 or 5290 or 5291 or 5293 or 5294 or 23533 or 5296 or 10870 or 8503 or 5295) |
➞ |
M_atp_c + M_pail4p_hs_16_0_18_0_c ➞ M_adp_c + M_h_c + M_pail34p_hs_16_0_18_0_c |
|
|
|
|
|
Reaction |
R_LPASE_18_2 R_LPASE_18_2
|
Lysophospholipase (C18:w)
[0.0
1000.0]
(5321 or 1178 or 29124) |
➞ |
M_h2o_c + M_lpchol_hs_18_2_c ➞ M_g3pc_c + M_h_c + M_lnlc_c |
|
|
|
|
|
Reaction |
R_LPS3_hs_18_2 R_LPS3_hs_18_2
|
LPS3 hs 18 2
[0.0
1000.0]
11343 |
➞ |
M_h2o_c + M_mag_hs_18_2_c ➞ M_glyc_c + M_h_c + M_lnlc_c |
|
|
|
|
|
Reaction |
R_GPAM_hs_18_2 R_GPAM_hs_18_2
|
GPAM hs 18 2
[0.0
1000.0]
57678 |
➞ |
M_glyc3p_c + M_lnlccoa_c ➞ M_alpha_hs_18_2_c + M_coa_c |
|
|
|
|
|
Reaction |
R_LPASE_18_1 R_LPASE_18_1
|
Lysophospholipase (C18:1)
[0.0
1000.0]
(5321 or 1178 or 29124) |
➞ |
M_h2o_c + M_lpchol_hs_18_1_c ➞ M_g3pc_c + M_h_c + M_ocdcea_c |
|
|
|
|
|
Reaction |
R_LPS3_hs_18_1 R_LPS3_hs_18_1
|
LPS3 hs 18 1
[0.0
1000.0]
11343 |
➞ |
M_h2o_c + M_mag_hs_18_1_c ➞ M_glyc_c + M_h_c + M_ocdcea_c |
|
|
|
|
|
Reaction |
R_AGPAT1_18_0_18_2 R_AGPAT1_18_0_18_2
|
AGPAT1 18 0 18 2
[0.0
1000.0]
(137964 or 56894 or 10554 or 10555 or 55326 or 56895) |
➞ |
M_alpha_hs_18_0_c + M_lnlccoa_c ➞ M_coa_c + M_pa_hs_18_0_18_2_c |
|
|
|
|
|
Reaction |
R_GPAM_hs_18_1 R_GPAM_hs_18_1
|
GPAM hs 18 1
[0.0
1000.0]
57678 |
➞ |
M_glyc3p_c + M_odecoa_c ➞ M_alpha_hs_18_1_c + M_coa_c |
|
|
|
|
|
Reaction |
R_LPASE_18_0 R_LPASE_18_0
|
LPASE 18 0
[0.0
1000.0]
(5321 or 1178 or 29124) |
➞ |
M_h2o_c + M_lpchol_hs_18_0_c ➞ M_g3pc_c + M_h_c + M_ocdca_c |
|
|
|
|
|
Reaction |
R_PI45PLC_18_0_18_1 R_PI45PLC_18_0_18_1
|
PI45PLC 18 0 18 1
[0.0
1000.0]
(113026 or 23236 or 84812 or 9651 or 257068 or 89869 or 5330 or 5331 or 5332 or 5333 or 5334 or 5335 or 5336 or 51196 or 23007) |
➞ |
M_h2o_c + M_pail45p_hs_18_0_18_1_c ➞ M_dag_hs_18_0_18_1_c + M_h_c + M_mi145p_c |
|
|
|
|
|
Reaction |
R_LPS3_hs_18_0 R_LPS3_hs_18_0
|
LPS3 hs 18 0
[0.0
1000.0]
11343 |
➞ |
M_h2o_c + M_mag_hs_18_0_c ➞ M_glyc_c + M_h_c + M_ocdca_c |
|
|
|
|
|
Reaction |
R_PI345P3P_18_0_18_1 R_PI345P3P_18_0_18_1
|
PI345P3P 18 0 18 1
[0.0
1000.0]
5728 |
➞ |
M_h2o_c + M_pail345p_hs_18_0_18_1_c ➞ M_pail45p_hs_18_0_18_1_c + M_pi_c |
|
|
|
|
|
Reaction |
R_GPAM_hs_18_0 R_GPAM_hs_18_0
|
GPAM hs 18 0
[0.0
1000.0]
57678 |
➞ |
M_glyc3p_c + M_stcoa_c ➞ M_alpha_hs_18_0_c + M_coa_c |
|
|
|
|
|
Reaction |
R_LPASE_16_0 R_LPASE_16_0
|
Lysophospholipase (C16:0)
[0.0
1000.0]
(5321 or 1178 or 29124) |
➞ |
M_h2o_c + M_lpchol_hs_16_0_c ➞ M_g3pc_c + M_h_c + M_hdca_c |
|
|
|
|
|
Reaction |
R_LPS3_hs_16_0 R_LPS3_hs_16_0
|
LPS3 hs 16 0
[0.0
1000.0]
11343 |
➞ |
M_h2o_c + M_mag_hs_16_0_c ➞ M_glyc_c + M_h_c + M_hdca_c |
|
|
|
|
|
Reaction |
R_EX_ile__L_e R_EX_ile__L_e
|
L-Isoleucine exchange
[-1000.0
1000.0]
|
⇆ |
M_ile__L_e ⇆ |
|
|
|
|
|
Reaction |
R_PI4P5K_18_0_18_1 R_PI4P5K_18_0_18_1
|
PI4P5K 18 0 18 1
[0.0
1000.0]
(200576 or 23396 or 8394 or 8395 or 8396 or 5305 or 79837) |
➞ |
M_atp_c + M_pail45p_hs_18_0_18_1_c ➞ M_adp_c + M_h_c + M_pail345p_hs_18_0_18_1_c |
|
|
|
|
|
Reaction |
R_GPAM_hs_16_0 R_GPAM_hs_16_0
|
GPAM hs 16 0
[0.0
1000.0]
57678 |
➞ |
M_glyc3p_c + M_pmtcoa_c ➞ M_alpha_hs_16_0_c + M_coa_c |
|
|
|
|
|
Reaction |
R_SK_pmtcrn_c R_SK_pmtcrn_c
|
EX pmtcrn e
[-1000.0
1000.0]
|
⇆ |
M_pmtcrn_c ⇆ |
|
|
|
|
|
Reaction |
R_PI34P5K_18_0_18_1 R_PI34P5K_18_0_18_1
|
PI34P5K 18 0 18 1
[0.0
1000.0]
(8394 or 8395 or 23396) |
➞ |
M_atp_c + M_pail34p_hs_18_0_18_1_c ➞ M_adp_c + M_h_c + M_pail345p_hs_18_0_18_1_c |
|
|
|
|
|
Reaction |
R_PI4P3K_18_0_18_1 R_PI4P3K_18_0_18_1
|
PI4P3K 18 0 18 1
[0.0
1000.0]
(5286 or 5287 or 5288 or 5290 or 5291 or 5293 or 5294 or 23533 or 5296 or 10870 or 8503 or 5295) |
➞ |
M_atp_c + M_pail4p_hs_18_0_18_1_c ➞ M_adp_c + M_h_c + M_pail34p_hs_18_0_18_1_c |
|
|
|
|
|
Reaction |
R_SK_fum_c R_SK_fum_c
|
EX fum e
[-1000.0
1000.0]
|
⇆ |
M_fum_c ⇆ |
|
|
|
|
|
Reaction |
R_CDS_16_0_20_4 R_CDS_16_0_20_4
|
CDS 16 0 20 4
[0.0
1000.0]
1040 |
➞ |
M_ctp_c + M_h_c + M_pa_hs_16_0_20_4_c ➞ M_cdpdag_hs_16_0_20_4_c + M_ppi_c |
|
|
|
|
|
Reaction |
R_LPS2_16_0_20_4 R_LPS2_16_0_20_4
|
LPS2 16 0 20 4
[0.0
1000.0]
4023 |
➞ |
M_dag_hs_16_0_20_4_c + M_h2o_c ➞ M_arachd_c + M_h_c + M_mag_hs_16_0_c |
|
|
|
|
|
Reaction |
R_PIt9 R_PIt9
|
Phosphate transport in/out via two Na+ symporter
[-1000.0
1000.0]
142680 |
⇆ |
2.0 M_na1_e + M_pi_e ⇆ 2.0 M_na1_c + M_pi_c |
|
|
|
|
|
Reaction |
R_SK_citr__L_c R_SK_citr__L_c
|
Sink citr c
[-1000.0
1000.0]
|
⇆ |
M_citr__L_c ⇆ |
|
|
|
|
|
Reaction |
R_SK_cholp_c R_SK_cholp_c
|
EX cholp e
[-1000.0
1000.0]
|
⇆ |
M_cholp_c ⇆ |
|
|
|
|
|
Reaction |
R_SK_cdpea_c R_SK_cdpea_c
|
EX cdpea e
[-1000.0
1000.0]
|
⇆ |
M_cdpea_c ⇆ |
|
|
|
|
|
Reaction |
R_SK_ahcys_c R_SK_ahcys_c
|
EX ahcys e
[-1000.0
1000.0]
|
⇆ |
M_ahcys_c ⇆ |
|
|
|
|
|
Reaction |
R_SK_acrn_c R_SK_acrn_c
|
EX acrn e
[-1000.0
1000.0]
|
⇆ |
M_acrn_c ⇆ |
|
|
|
|
|
Reaction |
R_SK_5oxpro_c R_SK_5oxpro_c
|
EX 5oxpro e
[-1000.0
1000.0]
|
⇆ |
M_5oxpro_c ⇆ |
|
|
|
|
|
Reaction |
R_TSULt4_3 R_TSULt4_3
|
Thiosulfate transport via sodium symport
[-1000.0
1000.0]
6561 |
⇆ |
3.0 M_na1_e + M_tsul_e ⇆ 3.0 M_na1_c + M_tsul_c |
|
|
|
|
|
Reaction |
R_H2Ot R_H2Ot
|
H2O transport via diffusion
[-1000.0
1000.0]
6523 |
⇆ |
M_h2o_e ⇆ M_h2o_c |
|
|
|
|
|
Reaction |
R_TRYPTAOX R_TRYPTAOX
|
Tryptamine:oxygen oxidoreductase(deaminating)(flavin-containing)
[0.0
1000.0]
(4128 or 4129) |
➞ |
M_h2o_c + M_o2_c + M_trypta_c ➞ M_h2o2_c + M_id3acald_c + M_nh4_c |
|
|
|
|
|
Reaction |
R_TRPt4 R_TRPt4
|
L-tryptophan transport in via sodium symport
[-1000.0
1000.0]
11254 |
⇆ |
M_na1_e + M_trp__L_e ⇆ M_na1_c + M_trp__L_c |
|
|
|
|
|
Reaction |
R_SK_3mob_c R_SK_3mob_c
|
EX 3mob e
[-1000.0
1000.0]
|
⇆ |
M_3mob_c ⇆ |
|
|
|
|
|
Reaction |
R_SK_etha_c R_SK_etha_c
|
Sink etha
[-1000.0
1000.0]
|
⇆ |
M_etha_c ⇆ |
|
|
|
|
|
Reaction |
R_XYLUR R_XYLUR
|
Xylulose reductase
[-1000.0
1000.0]
51181 |
⇆ |
M_h_c + M_nadph_c + M_xylu__L_c ⇆ M_nadp_c + M_xylt_c |
|
|
|
|
|
Reaction |
R_XYLTD_D R_XYLTD_D
|
Xylitol dehydrogenase D xyulose forming
[-1000.0
1000.0]
|
⇆ |
M_nad_c + M_xylt_c ⇆ M_h_c + M_nadh_c + M_xylu__D_c |
|
|
|
|
|
Reaction |
R_TRPt R_TRPt
|
L-tryptophan transport
[-1000.0
1000.0]
117247 |
⇆ |
M_trp__L_e ⇆ M_trp__L_c |
|
|
|
|
|
Reaction |
R_H2Otm R_H2Otm
|
H2O transport mitochondrial
[-1000.0
1000.0]
343 |
⇆ |
M_h2o_c ⇆ M_h2o_m |
|
|
|
|
|
Reaction |
R_TRPHYDRO2 R_TRPHYDRO2
|
L-Tryptophan,tetrahydrobiopterin:oxygen oxidoreductase (5-hydroxylating)
[0.0
1000.0]
(121278 or 7166) |
➞ |
M_o2_c + M_thbpt_c + M_trp__L_c ➞ M_5htrp_c + M_thbpt4acam_c |
|
|
|
|
|
Reaction |
R_TRIOK R_TRIOK
|
Triokinase
[0.0
1000.0]
|
➞ |
M_atp_c + M_glyald_c ➞ M_adp_c + M_g3p_c + M_h_c |
|
|
|
|
|
Reaction |
R_ATPtm R_ATPtm
|
ADP/ATP transporter, mitochondrial
[0.0
1000.0]
(291 or 292 or 293) |
➞ |
M_adp_c + M_atp_m ➞ M_adp_m + M_atp_c |
|
|
|
|
|
Reaction |
R_AMPt R_AMPt
|
AMPt
[-1000.0
1000.0]
|
⇆ |
M_amp_e ⇆ M_amp_c |
|
|
|
|
|
Reaction |
R_XYLK R_XYLK
|
Xylulokinase
[0.0
1000.0]
9942 |
➞ |
M_atp_c + M_xylu__D_c ➞ M_adp_c + M_h_c + M_xu5p__D_c |
|
|
|
|
|
Reaction |
R_ACCOAtm_1 R_ACCOAtm_1
|
Acetyl-CoATransporter(mito/cytosol)
[0.0
1000.0]
|
➞ |
M_accoa_c ➞ M_accoa_m |
|
|
|
|
|
Reaction |
R_XAOx R_XAOx
|
Xanthine oxidase,peroxisomal
[-1000.0
1000.0]
7498 |
⇆ |
M_h2o_x + M_o2_x + M_xan_x ⇆ M_h2o2_x + M_urate_x |
|
|
|
|
|
Reaction |
R_TPI R_TPI
|
Triose-phosphate isomerase
[-1000.0
1000.0]
7167 |
⇆ |
M_dhap_c ⇆ M_g3p_c |
|
|
|
|
|
Reaction |
R_ATPM R_ATPM
|
ATP maintenance requirement
[-1000.0
1000.0]
|
⇆ |
M_atp_c + M_h2o_c ⇆ M_adp_c + M_h_c + M_pi_c |
|
|
|
|
|
Reaction |
R_TMDPP R_TMDPP
|
Thymidine phosphorylase
[-1000.0
1000.0]
1890 |
⇆ |
M_pi_c + M_thymd_c ⇆ M_2dr1p_c + M_thym_c |
|
|
|
|
|
Reaction |
R_TKT2 R_TKT2
|
Transketolase
[-1000.0
1000.0]
7086 |
⇆ |
M_e4p_c + M_xu5p__D_c ⇆ M_f6p_c + M_g3p_c |
|
|
|
|
|
Reaction |
R_TKT1 R_TKT1
|
Transketolase
[-1000.0
1000.0]
7086 |
⇆ |
M_r5p_c + M_xu5p__D_c ⇆ M_g3p_c + M_s7p_c |
|
|
|
|
|
Reaction |
R_XANtx R_XANtx
|
Xanthine diffusion in peroxisome
[-1000.0
1000.0]
|
⇆ |
M_xan_c ⇆ M_xan_x |
|
|
|
|
|
Reaction |
R_VALtec R_VALtec
|
L-valine transport via diffusion (extracellular to cytosol)
[-1000.0
1000.0]
(8501 or 124935) |
⇆ |
M_val__L_e ⇆ M_val__L_c |
|
|
|
|
|
Reaction |
R_VALt4 R_VALt4
|
L-valine transport in via sodium symport
[-1000.0
1000.0]
11254 |
⇆ |
M_na1_e + M_val__L_e ⇆ M_na1_c + M_val__L_c |
|
|
|
|
|
Reaction |
R_VALTA R_VALTA
|
Valine transaminase
[-1000.0
1000.0]
586 |
⇆ |
M_akg_c + M_val__L_c ⇆ M_3mob_c + M_glu__L_c |
|
|
|
|
|
Reaction |
R_THYMt R_THYMt
|
Thymine reversible transport via facilated diffusion
[-1000.0
1000.0]
3177 |
⇆ |
M_thym_e ⇆ M_thym_c |
|
|
|
|
|
Reaction |
R_THYMDt1 R_THYMDt1
|
Thymd transport
[0.0
1000.0]
2030 |
➞ |
M_thymd_e ➞ M_thymd_c |
|
|
|
|
|
Reaction |
R_SK_adp_c R_SK_adp_c
|
Sink adp c
[-1000.0
1000.0]
|
⇆ |
M_adp_c ⇆ |
|
|
|
|
|
Reaction |
R_THMDt5 R_THMDt5
|
Thymidine transport (1:2 Na/Thymd cotransport)
[0.0
1000.0]
64078 |
➞ |
2.0 M_na1_e + M_thymd_e ➞ 2.0 M_na1_c + M_thymd_c |
|
|
|
|
|
Reaction |
R_URIt5 R_URIt5
|
Uridine transport in via sodium symport (1:2)
[-1000.0
1000.0]
64078 |
⇆ |
2.0 M_na1_e + M_uri_e ⇆ 2.0 M_na1_c + M_uri_c |
|
|
|
|
|
Reaction |
R_SK_glygn3_c R_SK_glygn3_c
|
DM glygn3 c
[-1000.0
1000.0]
|
⇆ |
M_glygn3_c ⇆ |
|
|
|
|
|
Reaction |
R_XAO2x R_XAO2x
|
Xanthine oxidase
[-1000.0
1000.0]
7498 |
⇆ |
M_h2o_x + M_hxan_x + M_o2_x ⇆ M_h2o2_x + M_xan_x |
|
|
|
|
|
Reaction |
R_HXANtx R_HXANtx
|
Hypoxanthine diffusion in peroxisome
[-1000.0
1000.0]
|
⇆ |
M_hxan_c ⇆ M_hxan_x |
|
|
|
|
|
Reaction |
R_URIt4 R_URIt4
|
Uridine transport in via sodium symport
[-1000.0
1000.0]
(9153 or 9154 or 64078) |
⇆ |
M_na1_e + M_uri_e ⇆ M_na1_c + M_uri_c |
|
|
|
|
|
Reaction |
R_THMDt4 R_THMDt4
|
Thymidine transport in via sodium symport
[0.0
1000.0]
(9154 or 64078) |
➞ |
M_na1_e + M_thymd_e ➞ M_na1_c + M_thymd_c |
|
|
|
|
|
Reaction |
R_PROD2m R_PROD2m
|
Proline dehydrogenase (m)
[0.0
1000.0]
5625 |
➞ |
M_fad_m + M_pro__L_m ➞ M_1pyr5c_m + M_fadh2_m + M_h_m |
|
|
|
|
|
Reaction |
R_THFtm R_THFtm
|
5,6,7,8-Tetrahydrofolate transport, diffusion, mitochondrial
[-1000.0
1000.0]
|
⇆ |
M_thf_c ⇆ M_thf_m |
|
|
|
|
|
Reaction |
R_URIt R_URIt
|
Uridine facilated transport in cytosol
[-1000.0
1000.0]
2030 |
⇆ |
M_uri_e ⇆ M_uri_c |
|
|
|
|
|
Reaction |
R_GLYt2r R_GLYt2r
|
Glycine reversible transport via proton symport
[-1000.0
1000.0]
206358 |
⇆ |
M_gly_e + M_h_e ⇆ M_gly_c + M_h_c |
|
|
|
|
|
Reaction |
R_THBPT4ACAMDASE R_THBPT4ACAMDASE
|
Tetrahydrobiopterin-4a-carbinolamine dehydratase
[0.0
1000.0]
5092 |
➞ |
M_thbpt4acam_c ➞ M_dhbpt_c + M_h2o_c |
|
|
|
|
|
Reaction |
R_SK_paf_hs_c R_SK_paf_hs_c
|
Sink paf hs
[-1000.0
1000.0]
|
⇆ |
M_paf_hs_c ⇆ |
|
|
|
|
|
Reaction |
R_TCYNTtm R_TCYNTtm
|
Thiocyanate transport via diffusion (mitochondrial)
[0.0
1000.0]
|
➞ |
M_tcynt_m ➞ M_tcynt_c |
|
|
|
|
|
Reaction |
R_TCYNTt R_TCYNTt
|
Thiocyanate transport via diffusion (cytosol to extracellular)
[0.0
1000.0]
|
➞ |
M_tcynt_c ➞ M_tcynt_e |
|
|
|
|
|
Reaction |
R_URIK1 R_URIK1
|
Uridine kinase ATPUridine
[0.0
1000.0]
83549 |
➞ |
M_atp_c + M_uri_c ➞ M_adp_c + M_h_c + M_ump_c |
|
|
|
|
|
Reaction |
R_UREAt5 R_UREAt5
|
Urea, water cotransport
[-1000.0
1000.0]
6523 |
⇆ |
M_h2o_e + M_urea_e ⇆ M_h2o_c + M_urea_c |
|
|
|
|
|
Reaction |
R_UREAt R_UREAt
|
Urea transport via facilitate diffusion
[-1000.0
1000.0]
(6528 or 8170 or 6563 or 6523) |
⇆ |
M_urea_e ⇆ M_urea_c |
|
|
|
|
|
Reaction |
R_URAt R_URAt
|
Uracil transport via facilated diffusion
[-1000.0
1000.0]
3177 |
⇆ |
M_ura_e ⇆ M_ura_c |
|
|
|
|
|
Reaction |
R_PAFt R_PAFt
|
1-Alkyl 2-Acteylglycerol 3-Phosphocholine Transport, Vescicular
[0.0
1000.0]
|
➞ |
M_paf_hs_e ➞ M_paf_hs_c |
|
|
|
|
|
Reaction |
R_URATEtx R_URATEtx
|
Urate export from peroxisome
[-1000.0
1000.0]
|
⇆ |
M_urate_x ⇆ M_urate_c |
|
|
|
|
|
Reaction |
R_URATEt R_URATEt
|
Urate export from cytosol
[-1000.0
1000.0]
|
⇆ |
M_urate_c ⇆ M_urate_e |
|
|
|
|
|
Reaction |
R_TALA R_TALA
|
Transaldolase
[-1000.0
1000.0]
6888 |
⇆ |
M_g3p_c + M_s7p_c ⇆ M_e4p_c + M_f6p_c |
|
|
|
|
|
Reaction |
R_SULFOX R_SULFOX
|
Sulfite oxidase
[0.0
1000.0]
6821 |
➞ |
2.0 M_ficytC_m + M_h2o_c + M_so3_c ➞ 2.0 M_focytC_m + 2.0 M_h_c + M_so4_c |
|
|
|
|
|
Reaction |
R_SUCOAS1m R_SUCOAS1m
|
Succinyl-CoA ligase (GDP-forming)
[-1000.0
1000.0]
(8801 and 8802) |
⇆ |
M_coa_m + M_gtp_m + M_succ_m ⇆ M_gdp_m + M_pi_m + M_succoa_m |
|
|
|
|
|
Reaction |
R_EX_paf_hs_e R_EX_paf_hs_e
|
1-alkyl 2-acteylglycerol 3-phosphocholine (homo sapiens) exchange
[-1000.0
1000.0]
|
⇆ |
M_paf_hs_e ⇆ |
|
|
|
|
|
Reaction |
R_SUCD1m R_SUCD1m
|
Succinate dehydrogenase
[-1000.0
1000.0]
(6392 and 6389 and 6390 and 6391) |
⇆ |
M_fad_m + M_succ_m ⇆ M_fadh2_m + M_fum_m |
|
|
|
|
|
Reaction |
R_SUCCt4_3 R_SUCCt4_3
|
Succinate transport via sodium symport
[-1000.0
1000.0]
64849 |
⇆ |
3.0 M_na1_e + M_succ_e ⇆ 3.0 M_na1_c + M_succ_c |
|
|
|
|
|
Reaction |
R_UPPN R_UPPN
|
B-ureidopropionase
[0.0
1000.0]
51733 |
➞ |
M_cala_c + M_h2o_c + 2.0 M_h_c ➞ M_ala_B_c + M_co2_c + M_nh4_c |
|
|
|
|
|
Reaction |
R_UPPDC1 R_UPPDC1
|
Uroporphyrinogen decarboxylase (uroporphyrinogen III)
[0.0
1000.0]
7389 |
➞ |
4.0 M_h_c + M_uppg3_c ➞ 4.0 M_co2_c + M_cpppg3_c |
|
|
|
|
|
Reaction |
R_SUCCt4_2 R_SUCCt4_2
|
Succinate transport via sodium symport
[-1000.0
1000.0]
9058 |
⇆ |
2.0 M_na1_e + M_succ_e ⇆ 2.0 M_na1_c + M_succ_c |
|
|
|
|
|
Reaction |
R_SUCCtm R_SUCCtm
|
Succinate transport mitochondrial
[-1000.0
1000.0]
1468 |
⇆ |
M_pi_m + M_succ_c ⇆ M_pi_c + M_succ_m |
|
|
|
|
|
Reaction |
R_UPP3S R_UPP3S
|
Uroporphyrinogen-III synthase
[0.0
1000.0]
7390 |
➞ |
M_hmbil_c ➞ M_h2o_c + M_uppg3_c |
|
|
|
|
|
Reaction |
R_SK_Tyr_ggn_c R_SK_Tyr_ggn_c
|
Sink for Tyr-194 Of Apo-Glycogenin Protein (Primer For Glycogen Synthesis)
[-1000.0
1000.0]
|
⇆ |
M_Tyr_ggn_c ⇆ |
|
|
|
|
|
Reaction |
R_UMPK4 R_UMPK4
|
UMP kinase (GTP)
[-1000.0
1000.0]
51727 |
⇆ |
M_gtp_c + M_ump_c ⇆ M_gdp_c + M_udp_c |
|
|
|
|
|
Reaction |
R_UMPK3 R_UMPK3
|
UMP kinase (UTP)
[-1000.0
1000.0]
51727 |
⇆ |
M_ump_c + M_utp_c ⇆ 2.0 M_udp_c |
|
|
|
|
|
Reaction |
R_STS2 R_STS2
|
Steryl-sulfatase
[0.0
1000.0]
412 |
➞ |
M_estrones_c + M_h2o_c ➞ M_estrone_c + M_h_c + M_so4_c |
|
|
|
|
|
Reaction |
R_UMPK2 R_UMPK2
|
UMP kinase (CTP)
[-1000.0
1000.0]
51727 |
⇆ |
M_ctp_c + M_ump_c ⇆ M_cdp_c + M_udp_c |
|
|
|
|
|
Reaction |
R_PYRt2m R_PYRt2m
|
Pyruvate mitochondrial transport via proton symport
[-1000.0
1000.0]
6566 |
⇆ |
M_h_c + M_pyr_c ⇆ M_h_m + M_pyr_m |
|
|
|
|
|
Reaction |
R_UMPK R_UMPK
|
UMP kinase
[-1000.0
1000.0]
51727 |
⇆ |
M_atp_c + M_ump_c ⇆ M_adp_c + M_udp_c |
|
|
|
|
|
Reaction |
R_UGLT R_UGLT
|
UDPglucose--hexose-1-phosphate uridylyltransferase
[-1000.0
1000.0]
2592 |
⇆ |
M_gal1p_c + M_udpg_c ⇆ M_g1p_c + M_udpgal_c |
|
|
|
|
|
Reaction |
R_UDPG4E R_UDPG4E
|
UDPglucose 4-epimerase
[-1000.0
1000.0]
2582 |
⇆ |
M_udpg_c ⇆ M_udpgal_c |
|
|
|
|
|
Reaction |
R_SSALxm R_SSALxm
|
Succinate-semialdehyde:NAD+ oxidoreductase, mitochondria
[0.0
1000.0]
7915 |
➞ |
M_h2o_m + M_nad_m + M_sucsal_m ➞ 2.0 M_h_m + M_nadh_m + M_succ_m |
|
|
|
|
|
Reaction |
R_SRTNt6_2_r R_SRTNt6_2_r
|
SRTNt6 LPAREN 2 RPAREN r
[-1000.0
1000.0]
6532 |
⇆ |
2.0 M_k_c + 2.0 M_na1_e + M_srtn_e ⇆ 2.0 M_k_e + 2.0 M_na1_c + M_srtn_c |
|
|
|
|
|
Reaction |
R_TYRt4 R_TYRt4
|
L-tyrosine transport in via sodium symport
[-1000.0
1000.0]
11254 |
⇆ |
M_na1_e + M_tyr__L_e ⇆ M_na1_c + M_tyr__L_c |
|
|
|
|
|
Reaction |
R_PAFS R_PAFS
|
Alkyl glycerol phosphocholine acetyl transferase
[0.0
1000.0]
|
➞ |
M_accoa_c + M_ak2lgchol_hs_c ➞ M_coa_c + M_paf_hs_c |
|
|
|
|
|
Reaction |
R_SPODMx R_SPODMx
|
Superoxide dismutase, peroxisome
[0.0
1000.0]
6647 |
➞ |
2.0 M_h_x + 2.0 M_o2s_x ➞ M_h2o2_x + M_o2_x |
|
|
|
|
|
Reaction |
R_SPODMm R_SPODMm
|
Superoxide dismutase
[0.0
1000.0]
6648 |
➞ |
2.0 M_h_m + 2.0 M_o2s_m ➞ M_h2o2_m + M_o2_m |
|
|
|
|
|
Reaction |
R_TYRt R_TYRt
|
L-tyrosine transport
[-1000.0
1000.0]
117247 |
⇆ |
M_tyr__L_e ⇆ M_tyr__L_c |
|
|
|
|
|
Reaction |
R_PAFH R_PAFH
|
Platelet-activating factor acetylhydrolase
[0.0
1000.0]
((5049 and 5050) or (5049 and 5050 and 5048) or 5051) |
➞ |
M_h2o_c + M_paf_hs_c ➞ M_ac_c + M_ak2lgchol_hs_c + M_h_c |
|
|
|
|
|
Reaction |
R_TYRTA R_TYRTA
|
Tyrosine transaminase
[-1000.0
1000.0]
2805 |
⇆ |
M_akg_c + M_tyr__L_c ⇆ M_34hpp_c + M_glu__L_c |
|
|
|
|
|
Reaction |
R_TYROXDAc R_TYROXDAc
|
Tyramine:oxygen oxidoreductase(deaminating)(flavin-containing) (cytosol)
[0.0
1000.0]
(4128 or 4129) |
➞ |
M_h2o_c + M_o2_c + M_tym_c ➞ M_4hoxpacd_c + M_h2o2_c + M_nh4_c |
|
|
|
|
|
Reaction |
R_TYRDOPO R_TYRDOPO
|
Tyrosine:dopa oxidase
[0.0
1000.0]
7299 |
➞ |
M_o2_c + 2.0 M_tyr__L_c ➞ 2.0 M_34dhphe_c |
|
|
|
|
|
Reaction |
R_TYRCBOX R_TYRCBOX
|
L-Tyrosine carboxy-lyase
[0.0
1000.0]
1644 |
➞ |
M_h_c + M_tyr__L_c ➞ M_co2_c + M_tym_c |
|
|
|
|
|
Reaction |
R_TYR3MO2 R_TYR3MO2
|
Tyrosine 3-monooxygenase
[0.0
1000.0]
7054 |
➞ |
M_o2_c + M_thbpt_c + M_tyr__L_c ➞ M_34dhphe_c + M_thbpt4acam_c |
|
|
|
|
|
Reaction |
R_SPODM R_SPODM
|
Superoxide dismutase
[0.0
1000.0]
6647 |
➞ |
2.0 M_h_c + 2.0 M_o2s_c ➞ M_h2o2_c + M_o2_c |
|
|
|
|
|
Reaction |
R_SPHS1Pte R_SPHS1Pte
|
Sphingosine-1-phosphate transport
[-1000.0
1000.0]
|
⇆ |
M_sphs1p_c ⇆ M_sphs1p_e |
|
|
|
|
|
Reaction |
R_SPHK21c R_SPHK21c
|
Sphingosine kinase
[0.0
1000.0]
56848 |
➞ |
M_atp_c + M_sphings_c ➞ M_adp_c + M_h_c + M_sphs1p_c |
|
|
|
|
|
Reaction |
R_TYMSULT R_TYMSULT
|
Tyramine Sulfotransferase
[0.0
1000.0]
6817 |
➞ |
M_paps_c + M_tym_c ➞ M_h_c + M_pap_c + M_tymsf_c |
|
|
|
|
|
Reaction |
R_TYMSFt R_TYMSFt
|
Tyramine O-sulfate transport (diffusion)
[0.0
1000.0]
|
➞ |
M_tymsf_c ➞ M_tymsf_e |
|
|
|
|
|
Reaction |
R_SPC_HSt R_SPC_HSt
|
Sphingosylphosphorylcholine transport (diffusion)
[-1000.0
1000.0]
|
⇆ |
M_spc_hs_c ⇆ M_spc_hs_e |
|
|
|
|
|
Reaction |
R_PI45PLC_20_4_20_4 R_PI45PLC_20_4_20_4
|
PI45PLC 20 4 20 4
[0.0
1000.0]
(113026 or 23236 or 84812 or 9651 or 257068 or 89869 or 5330 or 5331 or 5332 or 5333 or 5334 or 5335 or 5336 or 51196 or 23007) |
➞ |
M_h2o_c + M_pail45p_hs_20_4_20_4_c ➞ M_dag_hs_20_4_20_4_c + M_h_c + M_mi145p_c |
|
|
|
|
|
Reaction |
R_SO4t4_3 R_SO4t4_3
|
Sulfate transport via sodium symport
[-1000.0
1000.0]
6561 |
⇆ |
3.0 M_na1_e + M_so4_e ⇆ 3.0 M_na1_c + M_so4_c |
|
|
|
|
|
Reaction |
R_TXBS R_TXBS
|
TXBS
[0.0
1000.0]
|
➞ |
M_h2o_c + M_h_c + M_txa2_c ➞ M_txb2_c |
|
|
|
|
|
Reaction |
R_TXASr R_TXASr
|
Thromboxane-A synthase
[0.0
1000.0]
6916 |
➞ |
M_prostgh2_r ➞ M_txa2_r |
|
|
|
|
|
Reaction |
R_TXA2tr R_TXA2tr
|
Thromboxane A2 intracellular transport
[-1000.0
1000.0]
|
⇆ |
M_txa2_c ⇆ M_txa2_r |
|
|
|
|
|
Reaction |
R_PI345P3P_20_4_20_4 R_PI345P3P_20_4_20_4
|
PI345P3P 20 4 20 4
[0.0
1000.0]
5728 |
➞ |
M_h2o_c + M_pail345p_hs_20_4_20_4_c ➞ M_pail45p_hs_20_4_20_4_c + M_pi_c |
|
|
|
|
|
Reaction |
R_TXA2te R_TXA2te
|
Thromboxane A2 transport
[-1000.0
1000.0]
|
⇆ |
M_txa2_e ⇆ M_txa2_c |
|
|
|
|
|
Reaction |
R_PI4P5K_20_4_20_4 R_PI4P5K_20_4_20_4
|
PI4P5K 20 4 20 4
[0.0
1000.0]
(200576 or 23396 or 8394 or 8395 or 8396 or 5305 or 79837) |
➞ |
M_atp_c + M_pail45p_hs_20_4_20_4_c ➞ M_adp_c + M_h_c + M_pail345p_hs_20_4_20_4_c |
|
|
|
|
|
Reaction |
R_PI34P5K_20_4_20_4 R_PI34P5K_20_4_20_4
|
PI34P5K 20 4 20 4
[0.0
1000.0]
(8394 or 8395 or 23396) |
➞ |
M_atp_c + M_pail34p_hs_20_4_20_4_c ➞ M_adp_c + M_h_c + M_pail345p_hs_20_4_20_4_c |
|
|
|
|
|
Reaction |
R_SO4t4_2 R_SO4t4_2
|
Sulfate transport via sodium symport
[-1000.0
1000.0]
26266 |
⇆ |
2.0 M_na1_e + M_so4_e ⇆ 2.0 M_na1_c + M_so4_c |
|
|
|
|
|
Reaction |
R_SO4HCOtex R_SO4HCOtex
|
Sulfate transport via bicarbonate countertransport
[-1000.0
1000.0]
(284129 or 115111 or 115019 or 1836 or 10861 or 116369 or 1811) |
⇆ |
2.0 M_hco3_c + M_so4_e ⇆ 2.0 M_hco3_e + M_so4_c |
|
|
|
|
|
Reaction |
R_SO4CLtex2 R_SO4CLtex2
|
Sulfate transport via chloride countertransport (2:1)
[-1000.0
1000.0]
65010 |
⇆ |
M_cl_c + 2.0 M_so4_e ⇆ M_cl_e + 2.0 M_so4_c |
|
|
|
|
|
Reaction |
R_PI4P3K_20_4_20_4 R_PI4P3K_20_4_20_4
|
PI4P3K 20 4 20 4
[0.0
1000.0]
(5286 or 5287 or 5288 or 5290 or 5291 or 5293 or 5294 or 23533 or 5296 or 10870 or 8503 or 5295) |
➞ |
M_atp_c + M_pail4p_hs_20_4_20_4_c ➞ M_adp_c + M_h_c + M_pail34p_hs_20_4_20_4_c |
|
|
|
|
|
Reaction |
R_SMPD4 R_SMPD4
|
Sphingomyelinase
[0.0
1000.0]
|
➞ |
M_h2o_c + M_spc_hs_c ➞ M_cholp_c + M_h_c + M_sphings_c |
|
|
|
|
|
Reaction |
R_SFGTHi R_SFGTHi
|
S-Formylglutathione hydralase
[-1000.0
1000.0]
2098 |
⇆ |
M_Sfglutth_c + M_h2o_c ⇆ M_for_c + M_gthrd_c + M_h_c |
|
|
|
|
|
Reaction |
R_LPS2_18_2_20_4 R_LPS2_18_2_20_4
|
LPS2 18 2 20 4
[0.0
1000.0]
4023 |
➞ |
M_dag_hs_18_2_20_4_c + M_h2o_c ➞ M_arachd_c + M_h_c + M_mag_hs_18_2_c |
|
|
|
|
|
Reaction |
R_DAGK_hs_18_2_20_4 R_DAGK_hs_18_2_20_4
|
DAGK hs 18 2 20 4
[-1000.0
1000.0]
(1606 or 1607 or 1608 or 1609 or 9162 or 8525 or 8526 or 8527 or 160851) |
⇆ |
M_adp_c + M_h_c + M_pa_hs_18_2_20_4_c ⇆ M_atp_c + M_dag_hs_18_2_20_4_c |
|
|
|
|
|
Reaction |
R_PLA2_2_18_2_20_4 R_PLA2_2_18_2_20_4
|
PLA2 2 18 2 20 4
[0.0
1000.0]
(5320 or 8398) |
➞ |
M_h2o_c + M_pchol_hs_18_2_20_4_c ➞ M_arachd_c + M_h_c + M_lpchol_hs_18_2_c |
|
|
|
|
|
Reaction |
R_CEPTC_18_2_20_4 R_CEPTC_18_2_20_4
|
CEPTC 18 2 20 4
[0.0
1000.0]
(56994 or 10390) |
➞ |
M_cdpchol_c + M_dag_hs_18_2_20_4_c ➞ M_cmp_c + M_h_c + M_pchol_hs_18_2_20_4_c |
|
|
|
|
|
Reaction |
R_PSSA1_hs_18_2_20_4 R_PSSA1_hs_18_2_20_4
|
PSSA1 hs 18 2 20 4
[-1000.0
1000.0]
9791 |
⇆ |
M_chol_c + M_ps_hs_18_2_20_4_c ⇆ M_pchol_hs_18_2_20_4_c + M_ser__L_c |
|
|
|
|
|
Reaction |
R_SERGLNexR R_SERGLNexR
|
L-Serine/Glutamine reversible exchange
[-1000.0
1000.0]
(6520 and 56301) |
⇆ |
M_gln__L_c + M_ser__L_e ⇆ M_gln__L_e + M_ser__L_c |
|
|
|
|
|
Reaction |
R_PI4PLC_20_4_20_4 R_PI4PLC_20_4_20_4
|
PI4PLC 20 4 20 4
[0.0
1000.0]
(113026 or 23236 or 84812 or 9651 or 257068 or 89869 or 5330 or 5331 or 5332 or 5333 or 5334 or 5335 or 5336 or 51196 or 23007) |
➞ |
M_h2o_c + M_pail4p_hs_20_4_20_4_c ➞ M_dag_hs_20_4_20_4_c + M_h_c + M_mi14p_c |
|
|
|
|
|
Reaction |
R_SBTR R_SBTR
|
D sorbitol reductase
[0.0
1000.0]
(10327 or 8574 or 231) |
➞ |
M_glc__D_c + M_h_c + M_nadph_c ➞ M_nadp_c + M_sbt__D_c |
|
|
|
|
|
Reaction |
R_SBTD_D2 R_SBTD_D2
|
D sorbitol dehydrogenase D fructose producing
[0.0
1000.0]
6652 |
➞ |
M_nad_c + M_sbt__D_c ➞ M_fru_c + M_h_c + M_nadh_c |
|
|
|
|
|
Reaction |
R_SARDHm R_SARDHm
|
Sarcosine dehydrogenase (m)
[0.0
1000.0]
1757 |
➞ |
M_fad_m + M_sarcs_m + M_thf_m ➞ M_fadh2_m + M_gly_m + M_mlthf_m |
|
|
|
|
|
Reaction |
R_SADT R_SADT
|
Sulfate adenylyltransferase
[0.0
1000.0]
(9060 or 9061) |
➞ |
M_atp_c + M_h_c + M_so4_c ➞ M_aps_c + M_ppi_c |
|
|
|
|
|
Reaction |
R_PSSA2_hs_18_2_20_4 R_PSSA2_hs_18_2_20_4
|
PSSA2 hs 18 2 20 4
[-1000.0
1000.0]
81490 |
⇆ |
M_pe_hs_18_2_20_4_c + M_ser__L_c ⇆ M_etha_c + M_ps_hs_18_2_20_4_c |
|
|
|
|
|
Reaction |
R_CEPTE_18_2_20_4 R_CEPTE_18_2_20_4
|
CEPTE 18 2 20 4
[0.0
1000.0]
10390 |
➞ |
M_cdpea_c + M_dag_hs_18_2_20_4_c ➞ M_cmp_c + M_h_c + M_pe_hs_18_2_20_4_c |
|
|
|
|
|
Reaction |
R_PPPG9tm R_PPPG9tm
|
Protoporphyrinogen IX mitochondrial transport
[-1000.0
1000.0]
|
⇆ |
M_pppg9_c ⇆ M_pppg9_m |
|
|
|
|
|
Reaction |
R_PIK4_20_4_20_4 R_PIK4_20_4_20_4
|
PIK4 20 4 20 4
[0.0
1000.0]
(5297 or 5298 or 55361) |
➞ |
M_atp_c + M_pail_hs_20_4_20_4_c ➞ M_adp_c + M_h_c + M_pail4p_hs_20_4_20_4_c |
|
|
|
|
|
Reaction |
R_PIPLC_20_4_20_4 R_PIPLC_20_4_20_4
|
PIPLC 20 4 20 4
[0.0
1000.0]
(113026 or 23236 or 84812 or 257068 or 9651 or 89869 or 5330 or 5331 or 5332 or 5333 or 5334 or 5335 or 5336 or 51196 or 23007) |
➞ |
M_h2o_c + M_pail_hs_20_4_20_4_c ➞ M_dag_hs_20_4_20_4_c + M_h_c + M_mi1p__D_c |
|
|
|
|
|
Reaction |
R_SACCD4m R_SACCD4m
|
Saccharopine dehydrogenase (NAD, L-glutamate forming), mitochondrial
[0.0
1000.0]
10157 |
➞ |
M_h2o_m + M_nadp_m + M_saccrp__L_m ➞ M_L2aadp6sa_m + M_glu__L_m + M_h_m + M_nadph_m |
|
|
|
|
|
Reaction |
R_SACCD3m R_SACCD3m
|
Saccharopine dehydrogenase (NADP, L-lysine forming), mitochondrial
[0.0
1000.0]
10157 |
➞ |
M_akg_m + M_h_m + M_lys__L_m + M_nadph_m ➞ M_h2o_m + M_nadp_m + M_saccrp__L_m |
|
|
|
|
|
Reaction |
R_PPM R_PPM
|
Phosphopentomutase
[-1000.0
1000.0]
5236 |
⇆ |
M_r1p_c ⇆ M_r5p_c |
|
|
|
|
|
Reaction |
R_CDIPTr_20_4_20_4 R_CDIPTr_20_4_20_4
|
CDIPTr 20 4 20 4
[0.0
1000.0]
10423 |
➞ |
M_cdpdag_hs_20_4_20_4_c + M_inost_c ➞ M_cmp_c + M_h_c + M_pail_hs_20_4_20_4_c |
|
|
|
|
|
Reaction |
R_RPI R_RPI
|
Ribose-5-phosphate isomerase
[-1000.0
1000.0]
22934 |
⇆ |
M_r5p_c ⇆ M_ru5p__D_c |
|
|
|
|
|
Reaction |
R_CDS_20_4_20_4 R_CDS_20_4_20_4
|
CDS 20 4 20 4
[0.0
1000.0]
1040 |
➞ |
M_ctp_c + M_h_c + M_pa_hs_20_4_20_4_c ➞ M_cdpdag_hs_20_4_20_4_c + M_ppi_c |
|
|
|
|
|
Reaction |
R_RNMK R_RNMK
|
Ribosylnicotinamide kinase
[0.0
1000.0]
54981 |
➞ |
M_atp_c + M_rnam_c ➞ M_adp_c + M_h_c + M_nmn_c |
|
|
|
|
|
Reaction |
R_PPDOy R_PPDOy
|
Propane-1,2-diol:NADP+ 1-oxidoreductase
[0.0
1000.0]
(10327 or 8574 or 231) |
➞ |
M_h_c + M_lald__D_c + M_nadph_c ➞ M_12ppd__R_c + M_nadp_c |
|
|
|
|
|
Reaction |
R_LPS2_20_4_20_4 R_LPS2_20_4_20_4
|
LPS2 20 4 20 4
[0.0
1000.0]
4023 |
➞ |
M_dag_hs_20_4_20_4_c + M_h2o_c ➞ M_arachd_c + M_h_c + M_mag_hs_20_4_c |
|
|
|
|
|
Reaction |
R_DAGK_hs_20_4_20_4 R_DAGK_hs_20_4_20_4
|
DAGK hs 20 4 20 4
[-1000.0
1000.0]
(1606 or 1607 or 1608 or 1609 or 9162 or 8525 or 8526 or 8527 or 160851) |
⇆ |
M_adp_c + M_h_c + M_pa_hs_20_4_20_4_c ⇆ M_atp_c + M_dag_hs_20_4_20_4_c |
|
|
|
|
|
Reaction |
R_PLA2_2_20_4_20_4 R_PLA2_2_20_4_20_4
|
PLA2 2 20 4 20 4
[0.0
1000.0]
(5320 or 8398) |
➞ |
M_h2o_c + M_pchol_hs_20_4_20_4_c ➞ M_arachd_c + M_h_c + M_lpchol_hs_20_4_c |
|
|
|
|
|
Reaction |
R_CEPTC_20_4_20_4 R_CEPTC_20_4_20_4
|
CEPTC 20 4 20 4
[0.0
1000.0]
(56994 or 10390) |
➞ |
M_cdpchol_c + M_dag_hs_20_4_20_4_c ➞ M_cmp_c + M_h_c + M_pchol_hs_20_4_20_4_c |
|
|
|
|
|
Reaction |
R_LCARR R_LCARR
|
Lacaldehyde reductase (R-propane-1,2-diol forming)
[-1000.0
1000.0]
8574 |
⇆ |
M_h_c + M_lald__D_c + M_nadh_c ⇆ M_12ppd__R_c + M_nad_c |
|
|
|
|
|
Reaction |
R_PPCOACm R_PPCOACm
|
Propionyl-CoA carboxylase, mitochondrial
[0.0
1000.0]
(5096 and 5095) |
➞ |
M_atp_m + M_hco3_m + M_ppcoa_m ➞ M_adp_m + M_h_m + M_mmcoa__S_m + M_pi_m |
|
|
|
|
|
Reaction |
R_PYRt2 R_PYRt2
|
Pyruvate transport in via proton symport
[-1000.0
1000.0]
(9194 or 9123) |
⇆ |
M_h_e + M_pyr_e ⇆ M_h_c + M_pyr_c |
|
|
|
|
|
Reaction |
R_PYNP2r R_PYNP2r
|
Pyrimidine-nucleoside phosphorylase (uracil)
[-1000.0
1000.0]
(7378 or 151531) |
⇆ |
M_pi_c + M_uri_c ⇆ M_r1p_c + M_ura_c |
|
|
|
|
|
Reaction |
R_PSSA1_hs_20_4_20_4 R_PSSA1_hs_20_4_20_4
|
PSSA1 hs 20 4 20 4
[-1000.0
1000.0]
9791 |
⇆ |
M_chol_c + M_ps_hs_20_4_20_4_c ⇆ M_pchol_hs_20_4_20_4_c + M_ser__L_c |
|
|
|
|
|
Reaction |
R_PYK R_PYK
|
Pyruvate kinase
[0.0
1000.0]
(5313 or 5315) |
➞ |
M_adp_c + M_h_c + M_pep_c ➞ M_atp_c + M_pyr_c |
|
|
|
|
|
Reaction |
R_PUNP7 R_PUNP7
|
Purine-nucleoside phosphorylase (Xanthosine)
[-1000.0
1000.0]
4860 |
⇆ |
M_pi_c + M_xtsn_c ⇆ M_r1p_c + M_xan_c |
|
|
|
|
|
Reaction |
R_PPBNGS R_PPBNGS
|
Porphobilinogen synthase
[0.0
1000.0]
210 |
➞ |
2.0 M_5aop_c ➞ 2.0 M_h2o_c + M_h_c + M_ppbng_c |
|
|
|
|
|
Reaction |
R_PPA R_PPA
|
Inorganic diphosphatase
[0.0
1000.0]
5464 |
➞ |
M_h2o_c + M_ppi_c ➞ M_h_c + 2.0 M_pi_c |
|
|
|
|
|
Reaction |
R_PNP R_PNP
|
Purine nucleoside phosphorylase
[-1000.0
1000.0]
4860 |
⇆ |
M_pi_c + M_rnam_c ⇆ M_h_c + M_ncam_c + M_r1p_c |
|
|
|
|
|
Reaction |
R_PUNP6 R_PUNP6
|
Purine-nucleoside phosphorylase (Deoxyinosine)
[-1000.0
1000.0]
4860 |
⇆ |
M_din_c + M_pi_c ⇆ M_2dr1p_c + M_hxan_c |
|
|
|
|
|
Reaction |
R_PSSA2_hs_20_4_20_4 R_PSSA2_hs_20_4_20_4
|
PSSA2 hs 20 4 20 4
[-1000.0
1000.0]
81490 |
⇆ |
M_pe_hs_20_4_20_4_c + M_ser__L_c ⇆ M_etha_c + M_ps_hs_20_4_20_4_c |
|
|
|
|
|
Reaction |
R_PUNP5 R_PUNP5
|
Purine-nucleoside phosphorylase (Inosine)
[-1000.0
1000.0]
4860 |
⇆ |
M_ins_c + M_pi_c ⇆ M_hxan_c + M_r1p_c |
|
|
|
|
|
Reaction |
R_PUNP3 R_PUNP3
|
Purine-nucleoside phosphorylase (Guanosine)
[-1000.0
1000.0]
4860 |
⇆ |
M_gsn_c + M_pi_c ⇆ M_gua_c + M_r1p_c |
|
|
|
|
|
Reaction |
R_PUNP2 R_PUNP2
|
Purine-nucleoside phosphorylase (Deoxyadenosine)
[-1000.0
1000.0]
4860 |
⇆ |
M_dad_2_c + M_pi_c ⇆ M_2dr1p_c + M_ade_c |
|
|
|
|
|
Reaction |
R_PUNP1 R_PUNP1
|
Purine-nucleoside phosphorylase (Adenosine)
[-1000.0
1000.0]
4860 |
⇆ |
M_adn_c + M_pi_c ⇆ M_ade_c + M_r1p_c |
|
|
|
|
|
Reaction |
R_PIter R_PIter
|
Phosphate transport, endoplasmic reticulum
[-1000.0
1000.0]
2544 |
⇆ |
M_pi_r ⇆ M_pi_c |
|
|
|
|
|
Reaction |
R_PIt2m_2 R_PIt2m_2
|
Phosphate mitochondrial transport via proton symport
[-1000.0
1000.0]
|
⇆ |
2.0 M_h_c + M_pi_c ⇆ 2.0 M_h_m + M_pi_m |
|
|
|
|
|
Reaction |
R_PHYCBOXL R_PHYCBOXL
|
L-Phenylalanine carboxy-lyase
[0.0
1000.0]
1644 |
➞ |
M_h_c + M_phe__L_c ➞ M_co2_c + M_peamn_c |
|
|
|
|
|
Reaction |
R_PHEtec R_PHEtec
|
L-phenylalanine transport via diffusion (extracellular to cytosol)
[-1000.0
1000.0]
(124935 or 117247) |
⇆ |
M_phe__L_e ⇆ M_phe__L_c |
|
|
|
|
|
Reaction |
R_CEPTE_20_4_20_4 R_CEPTE_20_4_20_4
|
CEPTE 20 4 20 4
[0.0
1000.0]
10390 |
➞ |
M_cdpea_c + M_dag_hs_20_4_20_4_c ➞ M_cmp_c + M_h_c + M_pe_hs_20_4_20_4_c |
|
|
|
|
|
Reaction |
R_PRPPS R_PRPPS
|
Phosphoribosylpyrophosphate synthetase
[-1000.0
1000.0]
(5634 or 221823 or 5631) |
⇆ |
M_atp_c + M_r5p_c ⇆ M_amp_c + M_h_c + M_prpp_c |
|
|
|
|
|
Reaction |
R_PHEt4 R_PHEt4
|
L-phenylalanine transport in via sodium symport
[-1000.0
1000.0]
6541 |
⇆ |
M_na1_e + M_phe__L_e ⇆ M_na1_c + M_phe__L_c |
|
|
|
|
|
Reaction |
R_PPAP_20_4_20_4 R_PPAP_20_4_20_4
|
PPAP 20 4 20 4
[0.0
1000.0]
(8611 or 8612 or 8613) |
➞ |
M_h2o_c + M_pa_hs_20_4_20_4_c ➞ M_dag_hs_20_4_20_4_c + M_pi_c |
|
|
|
|
|
Reaction |
R_PHEMEtm R_PHEMEtm
|
Protoheme transport (mitochondria)
[-1000.0
1000.0]
|
⇆ |
M_pheme_m ⇆ M_pheme_c |
|
|
|
|
|
Reaction |
R_PROtm R_PROtm
|
L proline transport mitochondrial
[-1000.0
1000.0]
|
⇆ |
M_pro__L_c ⇆ M_pro__L_m |
|
|
|
|
|
Reaction |
R_PHEMEt R_PHEMEt
|
Heme transport
[-1000.0
1000.0]
113235 |
⇆ |
M_pheme_e ⇆ M_pheme_c |
|
|
|
|
|
Reaction |
R_AGPAT1_20_4_20_4 R_AGPAT1_20_4_20_4
|
AGPAT1 20 4 20 4
[0.0
1000.0]
(137964 or 56894 or 10554 or 10555 or 55326 or 56895) |
➞ |
M_alpha_hs_20_4_c + M_arachdcoa_c ➞ M_coa_c + M_pa_hs_20_4_20_4_c |
|
|
|
|
|
Reaction |
R_PHEACGLNt R_PHEACGLNt
|
PHEACGLN extracellular transport via diffusion
[-1000.0
1000.0]
|
⇆ |
M_pheacgln_c ⇆ M_pheacgln_e |
|
|
|
|
|
Reaction |
R_PROt4_2_r R_PROt4_2_r
|
PROt4 LPAREN 2 RPAREN r
[-1000.0
1000.0]
6534 |
⇆ |
2.0 M_na1_e + M_pro__L_e ⇆ 2.0 M_na1_c + M_pro__L_c |
|
|
|
|
|
Reaction |
R_PHACCOAGLNAC R_PHACCOAGLNAC
|
Phenylacetyl-CoA:L-glutamine alpha-N-phenylacetyltransferase
[0.0
1000.0]
|
➞ |
M_gln__L_c + M_phaccoa_c ➞ M_coa_c + M_pheacgln_c |
|
|
|
|
|
Reaction |
R_PI45PLC_18_2_20_4 R_PI45PLC_18_2_20_4
|
PI45PLC 18 2 20 4
[0.0
1000.0]
(113026 or 23236 or 84812 or 9651 or 257068 or 89869 or 5330 or 5331 or 5332 or 5333 or 5334 or 5335 or 5336 or 51196 or 23007) |
➞ |
M_h2o_c + M_pail45p_hs_18_2_20_4_c ➞ M_dag_hs_18_2_20_4_c + M_h_c + M_mi145p_c |
|
|
|
|
|
Reaction |
R_PGSr R_PGSr
|
Prostaglandin G/H synthase
[0.0
1000.0]
(5742 or 5743) |
➞ |
M_arachd_r + M_h_r + M_nadph_r + 2.0 M_o2_r ➞ M_h2o_r + M_nadp_r + M_prostgh2_r |
|
|
|
|
|
Reaction |
R_PGS_PO R_PGS_PO
|
PGS PO
[0.0
1000.0]
(5742 or 5743) |
➞ |
M_nadph_c + M_prostgg2_c ➞ M_h2o_c + M_nadp_c + M_prostgh2_c |
|
|
|
|
|
Reaction |
R_PROSTGD2t R_PROSTGD2t
|
Prostaglandin transport via bicarbonate countertransport
[-1000.0
1000.0]
6578 |
⇆ |
M_hco3_c + M_prostgd2_e ⇆ M_hco3_e + M_prostgd2_c |
|
|
|
|
|
Reaction |
R_PGS_COX R_PGS_COX
|
PGS COX
[0.0
1000.0]
(5742 or 5743) |
➞ |
M_arachd_c + M_h_c + 2.0 M_o2_c ➞ M_prostgg2_c |
|
|
|
|
|
Reaction |
R_PRFGS R_PRFGS
|
Phosphoribosylformylglycinamidine synthase
[0.0
1000.0]
5198 |
➞ |
M_atp_c + M_fgam_c + M_gln__L_c + M_h2o_c ➞ M_adp_c + M_fpram_c + M_glu__L_c + M_h_c + M_pi_c |
|
|
|
|
|
Reaction |
R_PGS R_PGS
|
Prostaglandin G/H synthase
[0.0
1000.0]
(5742 or 5743) |
➞ |
M_arachd_c + M_h_c + M_nadph_c + 2.0 M_o2_c ➞ M_h2o_c + M_nadp_c + M_prostgh2_c |
|
|
|
|
|
Reaction |
R_PI345P3P_18_2_20_4 R_PI345P3P_18_2_20_4
|
PI345P3P 18 2 20 4
[0.0
1000.0]
5728 |
➞ |
M_h2o_c + M_pail345p_hs_18_2_20_4_c ➞ M_pail45p_hs_18_2_20_4_c + M_pi_c |
|
|
|
|
|
Reaction |
R_PI4P5K_18_2_20_4 R_PI4P5K_18_2_20_4
|
PI4P5K 18 2 20 4
[0.0
1000.0]
(200576 or 23396 or 8394 or 8395 or 8396 or 5305 or 79837) |
➞ |
M_atp_c + M_pail45p_hs_18_2_20_4_c ➞ M_adp_c + M_h_c + M_pail345p_hs_18_2_20_4_c |
|
|
|
|
|
Reaction |
R_PGMT R_PGMT
|
Phosphoglucomutase
[-1000.0
1000.0]
(55276 or 5236) |
⇆ |
M_g1p_c ⇆ M_g6p_c |
|
|
|
|
|
Reaction |
R_PGM R_PGM
|
Phosphoglycerate mutase
[-1000.0
1000.0]
(5224 or 669 or 5223) |
⇆ |
M_2pg_c ⇆ M_3pg_c |
|
|
|
|
|
Reaction |
R_PRDX R_PRDX
|
Peroxidase (multiple substrates)
[0.0
1000.0]
8288 |
➞ |
M_h2o2_c + M_meoh_c ➞ M_fald_c + 2.0 M_h2o_c |
|
|
|
|
|
Reaction |
R_PGL R_PGL
|
6-phosphogluconolactonase
[0.0
1000.0]
25796 |
➞ |
M_6pgl_c + M_h2o_c ➞ M_6pgc_c + M_h_c |
|
|
|
|
|
Reaction |
R_PI34P5K_18_2_20_4 R_PI34P5K_18_2_20_4
|
PI34P5K 18 2 20 4
[0.0
1000.0]
(8394 or 8395 or 23396) |
➞ |
M_atp_c + M_pail34p_hs_18_2_20_4_c ➞ M_adp_c + M_h_c + M_pail345p_hs_18_2_20_4_c |
|
|
|
|
|
Reaction |
R_PGK R_PGK
|
Phosphoglycerate kinase
[-1000.0
1000.0]
(5232 or 5230) |
⇆ |
M_3pg_c + M_atp_c ⇆ M_13dpg_c + M_adp_c |
|
|
|
|
|
Reaction |
R_PRASCSi R_PRASCSi
|
Phosphoribosylaminoimidazolesuccinocarboxamide synthase
[-1000.0
1000.0]
10606 |
⇆ |
M_5aizc_c + M_asp__L_c + M_atp_c ⇆ M_25aics_c + M_adp_c + M_h_c + M_pi_c |
|
|
|
|
|
Reaction |
R_PRAIS R_PRAIS
|
Phosphoribosylaminoimidazole synthase
[0.0
1000.0]
2618 |
➞ |
M_atp_c + M_fpram_c ➞ M_adp_c + M_air_c + 2.0 M_h_c + M_pi_c |
|
|
|
|
|
Reaction |
R_PRAGSr R_PRAGSr
|
Phosphoribosylglycinamide synthase
[-1000.0
1000.0]
2618 |
⇆ |
M_atp_c + M_gly_c + M_pram_c ⇆ M_adp_c + M_gar_c + M_h_c + M_pi_c |
|
|
|
|
|
Reaction |
R_PPPGOm R_PPPGOm
|
Protoporphyrinogen oxidase mitochondrial
[0.0
1000.0]
5498 |
➞ |
3.0 M_o2_m + 2.0 M_pppg9_m ➞ 6.0 M_h2o_m + 2.0 M_ppp9_m |
|
|
|
|
|
Reaction |
R_PGI R_PGI
|
Glucose-6-phosphate isomerase
[-1000.0
1000.0]
2821 |
⇆ |
M_g6p_c ⇆ M_f6p_c |
|
|
|
|
|
Reaction |
R_PGDI R_PGDI
|
Prostaglandin-H2 D-isomerase [Precursor]
[-1000.0
1000.0]
(5730 or 27306) |
⇆ |
M_prostgh2_c ⇆ M_prostgd2_c |
|
|
|
|
|
Reaction |
R_PFK26 R_PFK26
|
6 phosphofructo 2 kinase
[0.0
1000.0]
(5208 or 5209 or 5210 or 5207) |
➞ |
M_atp_c + M_f6p_c ➞ M_adp_c + M_f26bp_c + M_h_c |
|
|
|
|
|
Reaction |
R_PI4P3K_18_2_20_4 R_PI4P3K_18_2_20_4
|
PI4P3K 18 2 20 4
[0.0
1000.0]
(5286 or 5287 or 5288 or 5290 or 5291 or 5293 or 5294 or 23533 or 5296 or 10870 or 8503 or 5295) |
➞ |
M_atp_c + M_pail4p_hs_18_2_20_4_c ➞ M_adp_c + M_h_c + M_pail34p_hs_18_2_20_4_c |
|
|
|
|
|
Reaction |
R_PFK R_PFK
|
Phosphofructokinase
[0.0
1000.0]
((5214 and 5211) or (5214 and 5213) or (5211 and 5213) or 5211 or 5213 or 5214) |
➞ |
M_atp_c + M_f6p_c ➞ M_adp_c + M_fdp_c + M_h_c |
|
|
|
|
|
Reaction |
R_GLNt R_GLNt
|
L-glutamine transport via diffusion
[-1000.0
1000.0]
|
⇆ |
M_gln__L_e ⇆ M_gln__L_c |
|
|
|
|
|
Reaction |
R_PI4PLC_18_2_20_4 R_PI4PLC_18_2_20_4
|
PI4PLC 18 2 20 4
[0.0
1000.0]
(113026 or 23236 or 84812 or 9651 or 257068 or 89869 or 5330 or 5331 or 5332 or 5333 or 5334 or 5335 or 5336 or 51196 or 23007) |
➞ |
M_h2o_c + M_pail4p_hs_18_2_20_4_c ➞ M_dag_hs_18_2_20_4_c + M_h_c + M_mi14p_c |
|
|
|
|
|
Reaction |
R_Ht R_Ht
|
Proton diffusion
[-1000.0
1000.0]
|
⇆ |
M_h_e ⇆ M_h_c |
|
|
|
|
|
Reaction |
R_PIK4_18_2_20_4 R_PIK4_18_2_20_4
|
PIK4 18 2 20 4
[0.0
1000.0]
(5297 or 5298 or 55361) |
➞ |
M_atp_c + M_pail_hs_18_2_20_4_c ➞ M_adp_c + M_h_c + M_pail4p_hs_18_2_20_4_c |
|
|
|
|
|
Reaction |
R_PEAMNO R_PEAMNO
|
Phenethylamine oxidase
[0.0
1000.0]
(4128 or 4129) |
➞ |
M_h2o_c + M_o2_c + M_peamn_c ➞ M_h2o2_c + M_nh4_c + M_pacald_c |
|
|
|
|
|
Reaction |
R_PDHm R_PDHm
|
Pyruvate dehydrogenase
[0.0
1000.0]
(((1738 and 8050) and (5161 and 5162) and 1737) or ((1738 and 8050) and (5160 and 5162) and 1737)) |
➞ |
M_coa_m + M_nad_m + M_pyr_m ➞ M_accoa_m + M_co2_m + M_nadh_m |
|
|
|
|
|
Reaction |
R_PIPLC_18_2_20_4 R_PIPLC_18_2_20_4
|
PIPLC 18 2 20 4
[0.0
1000.0]
(113026 or 23236 or 84812 or 257068 or 9651 or 89869 or 5330 or 5331 or 5332 or 5333 or 5334 or 5335 or 5336 or 51196 or 23007) |
➞ |
M_h2o_c + M_pail_hs_18_2_20_4_c ➞ M_dag_hs_18_2_20_4_c + M_h_c + M_mi1p__D_c |
|
|
|
|
|
Reaction |
R_PDE4 R_PDE4
|
3',5'-cyclic-nucleotide phosphodiesterase
[0.0
1000.0]
((5145 and 5146 and 5147 and 5158 and 5148) or (5145 and 5158 and 5149) or 5152 or 5153 or 5148 or 8654 or 5136 or 5137 or 5138 or 5139 or 5140 or 5146 or 5147 or 50940 or 10846) |
➞ |
M_35cgmp_c + M_h2o_c ➞ M_gmp_c + M_h_c |
|
|
|
|
|
Reaction |
R_CDIPTr_18_2_20_4 R_CDIPTr_18_2_20_4
|
CDIPTr 18 2 20 4
[0.0
1000.0]
10423 |
➞ |
M_cdpdag_hs_18_2_20_4_c + M_inost_c ➞ M_cmp_c + M_h_c + M_pail_hs_18_2_20_4_c |
|
|
|
|
|
Reaction |
R_PDE1 R_PDE1
|
3',5'-cyclic-nucleotide phosphodiesterase
[0.0
1000.0]
(5144 or 5139) |
➞ |
M_camp_c + M_h2o_c ➞ M_amp_c + M_h_c |
|
|
|
|
|
Reaction |
R_NH4t3r R_NH4t3r
|
Ammonia transport via proton antiport
[-1000.0
1000.0]
(6005 or 57127) |
⇆ |
M_h_e + M_nh4_c ⇆ M_h_c + M_nh4_e |
|
|
|
|
|
Reaction |
R_PACCOAL R_PACCOAL
|
Phenylacetate-CoA ligase
[0.0
1000.0]
|
➞ |
M_atp_c + M_coa_c + M_pac_c ➞ M_amp_c + M_phaccoa_c + M_ppi_c |
|
|
|
|
|
Reaction |
R_CDS_18_2_20_4 R_CDS_18_2_20_4
|
CDS 18 2 20 4
[0.0
1000.0]
1040 |
➞ |
M_ctp_c + M_h_c + M_pa_hs_18_2_20_4_c ➞ M_cdpdag_hs_18_2_20_4_c + M_ppi_c |
|
|
|
|
|
Reaction |
R_NaKt R_NaKt
|
Na+/K+ exchanging ATPase
[0.0
1000.0]
((481 and 478) or (477 and 23439) or (476 and 483) or (481 and 480) or (482 and 478) or (482 and 476) or (482 and 477) or (481 and 476) or (23439 and 476) or (23439 and 480) or (481 and 477)) |
➞ |
M_atp_c + M_h2o_c + 2.0 M_k_e + 3.0 M_na1_c ➞ M_adp_c + M_h_c + 2.0 M_k_c + 3.0 M_na1_e + M_pi_c |
|
|
|
|
|
Reaction |
R_P5CRxm R_P5CRxm
|
Pyrroline-5-carboxylate reductase (m)
[0.0
1000.0]
5831 |
➞ |
M_1pyr5c_m + 2.0 M_h_m + M_nadh_m ➞ M_nad_m + M_pro__L_m |
|
|
|
|
|
Reaction |
R_P5CRm R_P5CRm
|
Pyrroline-5-carboxylate reductase, mitochondria
[0.0
1000.0]
5831 |
➞ |
M_1pyr5c_m + 2.0 M_h_m + M_nadph_m ➞ M_nadp_m + M_pro__L_m |
|
|
|
|
|
Reaction |
R_ORNt R_ORNt
|
Ornithine transport via diffusion
[0.0
1000.0]
6541 |
➞ |
M_orn_e ➞ M_orn_c |
|
|
|
|
|
Reaction |
R_COAtim R_COAtim
|
CoA transporter mitochondrial irreversible
[-1000.0
1000.0]
8034 |
⇆ |
M_coa_c ⇆ M_coa_m |
|
|
|
|
|
Reaction |
R_NTD9e R_NTD9e
|
5'-nucleotidase (GMP), extracellular
[0.0
1000.0]
4907 |
➞ |
M_gmp_e + M_h2o_e ➞ M_gsn_e + M_pi_e |
|
|
|
|
|
Reaction |
R_ORNt4m R_ORNt4m
|
Ornithine mitochondrial transport exchange with citruline
[-1000.0
1000.0]
10166 |
⇆ |
M_citr__L_c + M_h_c + M_orn_m ⇆ M_citr__L_m + M_h_m + M_orn_c |
|
|
|
|
|
Reaction |
R_NTD7e R_NTD7e
|
5'-nucleotidase (AMP), extracellular
[0.0
1000.0]
4907 |
➞ |
M_amp_e + M_h2o_e ➞ M_adn_e + M_pi_e |
|
|
|
|
|
Reaction |
R_ORNt3m R_ORNt3m
|
Ornithine mitochondrial transport via proton antiport
[-1000.0
1000.0]
10166 |
⇆ |
M_h_c + M_orn_m ⇆ M_h_m + M_orn_c |
|
|
|
|
|
Reaction |
R_ORNTArm R_ORNTArm
|
L-Ornithine:2-oxo-acid aminotransferase
[-1000.0
1000.0]
4942 |
⇆ |
M_akg_m + M_orn_m ⇆ M_glu5sa_m + M_glu__L_m |
|
|
|
|
|
Reaction |
R_OPAH R_OPAH
|
5-Oxoproline amidohydrolase (ATP-hydrolysing) (ir)
[0.0
1000.0]
26873 |
➞ |
M_5oxpro_c + M_atp_c + 2.0 M_h2o_c ➞ M_adp_c + M_glu__L_c + M_h_c + M_pi_c |
|
|
|
|
|
Reaction |
R_CO2tm R_CO2tm
|
CO2 transport diffusion mitochondrial
[-1000.0
1000.0]
|
⇆ |
M_co2_c ⇆ M_co2_m |
|
|
|
|
|
Reaction |
R_SUCOASm R_SUCOASm
|
Succinate CoA ligase ADP forming
[-1000.0
1000.0]
(8802 and 8803) |
⇆ |
M_atp_m + M_coa_m + M_succ_m ⇆ M_adp_m + M_pi_m + M_succoa_m |
|
|
|
|
|
Reaction |
R_OIVD3m R_OIVD3m
|
2-oxoisovalerate dehydrogenase (acylating; 3-methyl-2-oxopentanoate), mitochondrial
[0.0
1000.0]
((594 and 593) and 1629 and 1738) |
➞ |
M_3mop_m + M_coa_m + M_nad_m ➞ M_2mbcoa_m + M_co2_m + M_nadh_m |
|
|
|
|
|
Reaction |
R_OIVD2m R_OIVD2m
|
2-oxoisovalerate dehydrogenase (acylating; 3-methyl-2-oxobutanoate), mitochondrial
[0.0
1000.0]
((594 and 593) and 1629 and 1738) |
➞ |
M_3mob_m + M_coa_m + M_nad_m ➞ M_co2_m + M_ibcoa_m + M_nadh_m |
|
|
|
|
|
Reaction |
R_NTD4 R_NTD4
|
5'-nucleotidase (CMP)
[0.0
1000.0]
51251 |
➞ |
M_cmp_c + M_h2o_c ➞ M_cytd_c + M_pi_c |
|
|
|
|
|
Reaction |
R_OIVD1m R_OIVD1m
|
2-oxoisovalerate dehydrogenase (acylating; 4-methyl-2-oxopentaoate), mitochondrial
[0.0
1000.0]
((594 and 593) and 1629 and 1738) |
➞ |
M_4mop_m + M_coa_m + M_nad_m ➞ M_co2_m + M_ivcoa_m + M_nadh_m |
|
|
|
|
|
Reaction |
R_OCOAT1m R_OCOAT1m
|
3-oxoacid CoA-transferase
[-1000.0
1000.0]
5019 |
⇆ |
M_acac_m + M_succoa_m ⇆ M_aacoa_m + M_succ_m |
|
|
|
|
|
Reaction |
R_OCDCEAt R_OCDCEAt
|
Octadecenoate n C181 transport in via uniport
[-1000.0
1000.0]
|
⇆ |
M_ocdcea_e ⇆ M_ocdcea_c |
|
|
|
|
|
Reaction |
R_OCDCAt R_OCDCAt
|
Octadecanoate n C180 transport in via uniport
[-1000.0
1000.0]
|
⇆ |
M_ocdca_e ⇆ M_ocdca_c |
|
|
|
|
|
Reaction |
R_GLCter R_GLCter
|
Glucose transport, endoplasmic reticulum
[-1000.0
1000.0]
|
⇆ |
M_glc__D_c ⇆ M_glc__D_r |
|
|
|
|
|
Reaction |
R_GLCt1 R_GLCt1
|
Glucose transport uniport
[-1000.0
1000.0]
(144195 or 56606 or 11182 or 6515) |
⇆ |
M_glc__D_e ⇆ M_glc__D_c |
|
|
|
|
|
Reaction |
R_NTD2 R_NTD2
|
5'-nucleotidase (UMP)
[0.0
1000.0]
51251 |
➞ |
M_h2o_c + M_ump_c ➞ M_pi_c + M_uri_c |
|
|
|
|
|
Reaction |
R_OCBTm R_OCBTm
|
Ornithine carbamoyltransferase, irreversible
[0.0
1000.0]
5009 |
➞ |
M_cbp_m + M_orn_m ➞ M_citr__L_m + M_h_m + M_pi_m |
|
|
|
|
|
Reaction |
R_GLCURter R_GLCURter
|
Glucuronate endoplasmic reticular transport
[0.0
1000.0]
|
➞ |
M_glcur_c ➞ M_glcur_r |
|
|
|
|
|
Reaction |
R_NTD11 R_NTD11
|
5'-nucleotidase (IMP)
[0.0
1000.0]
(93034 or 22978) |
➞ |
M_h2o_c + M_imp_c ➞ M_ins_c + M_pi_c |
|
|
|
|
|
Reaction |
R_O2tm R_O2tm
|
O2 transport diffusion
[-1000.0
1000.0]
|
⇆ |
M_o2_c ⇆ M_o2_m |
|
|
|
|
|
Reaction |
R_NTD10 R_NTD10
|
5'-nucleotidase (XMP)
[0.0
1000.0]
22978 |
➞ |
M_h2o_c + M_xmp_c ➞ M_pi_c + M_xtsn_c |
|
|
|
|
|
Reaction |
R_NRPPHRSULT R_NRPPHRSULT
|
Norepinephrine Sulfotransferase
[0.0
1000.0]
6818 |
➞ |
M_nrpphr_c + M_paps_c ➞ M_h_c + M_nrpphrsf_c + M_pap_c |
|
|
|
|
|
Reaction |
R_O2ter R_O2ter
|
O2 transport endoplasmic reticulum
[-1000.0
1000.0]
|
⇆ |
M_o2_c ⇆ M_o2_r |
|
|
|
|
|
Reaction |
R_O2t R_O2t
|
O2 transport diffusion
[-1000.0
1000.0]
|
⇆ |
M_o2_e ⇆ M_o2_c |
|
|
|
|
|
Reaction |
R_GLBRAN R_GLBRAN
|
1,4-alpha-glucan branching enzyme (glygn1 -> glygn2)
[0.0
1000.0]
2632 |
➞ |
M_glygn1_c ➞ M_glygn2_c |
|
|
|
|
|
Reaction |
R_NRPPHRSFt R_NRPPHRSFt
|
Norepinephrine sulfate transport (diffusion)
[0.0
1000.0]
|
➞ |
M_nrpphrsf_c ➞ M_nrpphrsf_e |
|
|
|
|
|
Reaction |
R_O2Stx R_O2Stx
|
Superoxide anion transport via diffusion (peroxisome)
[-1000.0
1000.0]
|
⇆ |
M_o2s_c ⇆ M_o2s_x |
|
|
|
|
|
Reaction |
R_O2Stm R_O2Stm
|
Superoxide anion transport via diffusion (mitochondria)
[-1000.0
1000.0]
|
⇆ |
M_o2s_c ⇆ M_o2s_m |
|
|
|
|
|
Reaction |
R_O2St R_O2St
|
Superoxide anion transport via diffusion (extracellular)
[-1000.0
1000.0]
|
⇆ |
M_o2s_c ⇆ M_o2s_e |
|
|
|
|
|
Reaction |
R_NOt R_NOt
|
NO transport (diffusion)
[-1000.0
1000.0]
|
⇆ |
M_no_e ⇆ M_no_c |
|
|
|
|
|
Reaction |
R_GK1 R_GK1
|
Guanylate kinase (GMP:ATP)
[-1000.0
1000.0]
2987 |
⇆ |
M_atp_c + M_gmp_c ⇆ M_adp_c + M_gdp_c |
|
|
|
|
|
Reaction |
R_NOS2 R_NOS2
|
Nitric Oxide Synthase (NO forming)
[0.0
1000.0]
(4843 or 4846) |
➞ |
M_nadph_c + 2.0 M_nwharg_c + 2.0 M_o2_c ➞ 2.0 M_citr__L_c + 2.0 M_h2o_c + M_h_c + M_nadp_c + 2.0 M_no_c |
|
|
|
|
|
Reaction |
R_GHMT2r R_GHMT2r
|
Glycine hydroxymethyltransferase, reversible
[-1000.0
1000.0]
6470 |
⇆ |
M_ser__L_c + M_thf_c ⇆ M_gly_c + M_h2o_c + M_mlthf_c |
|
|
|
|
|
Reaction |
R_GLGNS1 R_GLGNS1
|
Glycogen synthase (ggn -> glygn1)
[0.0
1000.0]
(2992 and 8908 and 2997 and 2998) |
➞ |
M_ggn_c + 3.0 M_udpg_c ➞ M_glygn1_c + 3.0 M_h_c + 3.0 M_udp_c |
|
|
|
|
|
Reaction |
R_GGT6 R_GGT6
|
Gamma-glutamyltransferase
[-1000.0
1000.0]
|
⇆ |
M_glu__L_c + M_leuktrE4_c ⇆ M_h2o_c + M_leuktrF4_c |
|
|
|
|
|
Reaction |
R_NOS1 R_NOS1
|
L-Arginine,NADPH:oxygen oxidoreductase (N-(omega)-hydroxyarginine-forming)
[0.0
1000.0]
(4843 or 4846) |
➞ |
M_arg__L_c + M_h_c + M_nadph_c + M_o2_c ➞ M_h2o_c + M_nadp_c + M_nwharg_c |
|
|
|
|
|
Reaction |
R_GGT5r R_GGT5r
|
Gamma-glutamyltransferase 5
[-1000.0
1000.0]
2687 |
⇆ |
M_h2o_r + M_leuktrC4_r ⇆ M_glu__L_r + M_leuktrD4_r |
|
|
|
|
|
Reaction |
R_GGNG R_GGNG
|
Glycogenin self-glucosylation
[0.0
1000.0]
(2992 and 8908 and 2997 and 2998) |
➞ |
M_Tyr_ggn_c + 8.0 M_udpg_c ➞ M_ggn_c + 8.0 M_h_c + 8.0 M_udp_c |
|
|
|
|
|
Reaction |
R_GGLUCT R_GGLUCT
|
Gamma-glutamylcyclotransferase
[0.0
1000.0]
2655 |
➞ |
M_gluala_e ➞ M_5oxpro_c + M_ala__L_c |
|
|
|
|
|
Reaction |
R_GGH_10FTHF7GLUl R_GGH_10FTHF7GLUl
|
Gamma-glutamyl hydrolase (10FTHF7GLU), lysosomal
[0.0
1000.0]
8836 |
➞ |
M_10fthf7glu_l + M_h2o_l ➞ M_10fthf6glu_l + M_glu__L_l |
|
|
|
|
|
Reaction |
R_GGH_10FTHF6GLUl R_GGH_10FTHF6GLUl
|
Gamma-glutamyl hydrolase (10FTHF6GLU), lysosomal
[0.0
1000.0]
8836 |
➞ |
M_10fthf6glu_l + M_h2o_l ➞ M_10fthf5glu_l + M_glu__L_l |
|
|
|
|
|
Reaction |
R_GGH_10FTHF5GLUl R_GGH_10FTHF5GLUl
|
Gamma-glutamyl hydrolase (10FTHF5GLU), lysosomal
[0.0
1000.0]
8836 |
➞ |
M_10fthf5glu_l + 4.0 M_h2o_l ➞ M_10fthf_l + 4.0 M_glu__L_l |
|
|
|
|
|
Reaction |
R_GLDBRAN R_GLDBRAN
|
Glycogen debranching enzyme
[0.0
1000.0]
178 |
➞ |
M_dxtrn_c + M_h2o_c ➞ M_glc__D_c + M_glygn3_c |
|
|
|
|
|
Reaction |
R_NORANMT R_NORANMT
|
Noradrenaline N-methyltransferase
[0.0
1000.0]
5409 |
➞ |
M_amet_c + M_nrpphr_c ➞ M_adrnl_c + M_ahcys_c + M_h_c |
|
|
|
|
|
Reaction |
R_ENO R_ENO
|
Enolase
[-1000.0
1000.0]
(2026 or 2027 or 2023) |
⇆ |
M_2pg_c ⇆ M_h2o_c + M_pep_c |
|
|
|
|
|
Reaction |
R_GARFT R_GARFT
|
Phosphoribosylglycinamide formyltransferase
[-1000.0
1000.0]
2618 |
⇆ |
M_10fthf_c + M_gar_c ⇆ M_fgam_c + M_h_c + M_thf_c |
|
|
|
|
|
Reaction |
R_GAPD R_GAPD
|
Glyceraldehyde-3-phosphate dehydrogenase
[-1000.0
1000.0]
2597 |
⇆ |
M_g3p_c + M_nad_c + M_pi_c ⇆ M_13dpg_c + M_h_c + M_nadh_c |
|
|
|
|
|
Reaction |
R_NMNAT R_NMNAT
|
Nicotinamide-nucleotide adenylyltransferase
[-1000.0
1000.0]
(23057 or 349565) |
⇆ |
M_atp_c + M_h_c + M_nmn_c ⇆ M_nad_c + M_ppi_c |
|
|
|
|
|
Reaction |
R_GALt1r R_GALt1r
|
Galactose transport (uniport)
[-1000.0
1000.0]
6515 |
⇆ |
M_gal_e ⇆ M_gal_c |
|
|
|
|
|
Reaction |
R_NDPK3 R_NDPK3
|
Nucleoside-diphosphate kinase (ATP:CDP)
[-1000.0
1000.0]
((4831 and 4830) or 4832 or 10201 or 29922) |
⇆ |
M_atp_c + M_cdp_c ⇆ M_adp_c + M_ctp_c |
|
|
|
|
|
Reaction |
R_GALUi R_GALUi
|
UTP-glucose-1-phosphate uridylyltransferase (irreversible)
[-1000.0
1000.0]
7360 |
⇆ |
M_g1p_c + M_h_c + M_utp_c ⇆ M_ppi_c + M_udpg_c |
|
|
|
|
|
Reaction |
R_NDPK2 R_NDPK2
|
Nucleoside-diphosphate kinase (ATP:UDP)
[-1000.0
1000.0]
((4831 and 4830) or 4832 or 10201 or 29922) |
⇆ |
M_atp_c + M_udp_c ⇆ M_adp_c + M_utp_c |
|
|
|
|
|
Reaction |
R_GALT R_GALT
|
Galactose 1 phosphate uridylyltransferase
[-1000.0
1000.0]
2592 |
⇆ |
M_gal1p_c + M_h_c + M_utp_c ⇆ M_ppi_c + M_udpgal_c |
|
|
|
|
|
Reaction |
R_GALKr R_GALKr
|
Galactokinase
[0.0
1000.0]
2584 |
➞ |
M_atp_c + M_gal_c ➞ M_adp_c + M_gal1p_c + M_h_c |
|
|
|
|
|
Reaction |
R_ECOAH9m R_ECOAH9m
|
Enoyl-coa hydratase, 3-Hydroxy-2-methylbutyryl-CoA forming
[-1000.0
1000.0]
(3032 and 1892 and 3030) |
⇆ |
M_2mb2coa_m + M_h2o_m ⇆ M_3hmbcoa_m |
|
|
|
|
|
Reaction |
R_ECOAH1m R_ECOAH1m
|
3-Hydroxybutanoyl-CoA hydro-lyase, mitochondria
[-1000.0
1000.0]
(3032 and 1892 and 549 and 3030) |
⇆ |
M_3hbcoa_m ⇆ M_b2coa_m + M_h2o_m |
|
|
|
|
|
Reaction |
R_NDPK1m R_NDPK1m
|
Nucleoside-diphosphate kinase (ATP:GDP), mitochondrial
[-1000.0
1000.0]
4833 |
⇆ |
M_atp_m + M_gdp_m ⇆ M_adp_m + M_gtp_m |
|
|
|
|
|
Reaction |
R_ECOAH12m R_ECOAH12m
|
Enoyl-coa hydratase, 3-Hydroxyisobutyryl-CoA forming
[-1000.0
1000.0]
(3032 and 1892 and 3030) |
⇆ |
M_2mp2coa_m + M_h2o_m ⇆ M_3hibutcoa_m |
|
|
|
|
|
Reaction |
R_NDPK1 R_NDPK1
|
Nucleoside-diphosphate kinase (ATP:GDP)
[-1000.0
1000.0]
((4831 and 4830) or 4832 or 10201 or 29922) |
⇆ |
M_atp_c + M_gdp_c ⇆ M_adp_c + M_gtp_c |
|
|
|
|
|
Reaction |
R_GACMTRc R_GACMTRc
|
Guanidinoacetate N-methyltransferase (c)
[-1000.0
1000.0]
2593 |
⇆ |
M_amet_c + M_gudac_c ⇆ M_ahcys_c + M_creat_c + M_h_c |
|
|
|
|
|
Reaction |
R_NDP3ex R_NDP3ex
|
Nucleoside-diphosphatase (GDP), extracellular
[0.0
1000.0]
124583 |
➞ |
M_gdp_e + M_h2o_e ➞ M_gmp_e + M_h_e + M_pi_e |
|
|
|
|
|
Reaction |
R_G6Pter R_G6Pter
|
Glucose 6 phosphate endoplasmic reticular transport via diffusion
[-1000.0
1000.0]
2542 |
⇆ |
M_g6p_c ⇆ M_g6p_r |
|
|
|
|
|
Reaction |
R_G6PPer R_G6PPer
|
Glucose-6-phosphate phosphatase, edoplasmic reticular
[0.0
1000.0]
(57818 or 92579 or 2538) |
➞ |
M_g6p_r + M_h2o_r ➞ M_glc__D_r + M_pi_r |
|
|
|
|
|
Reaction |
R_DURAD R_DURAD
|
Dihydrouracil dehydrogenase (NADP)
[-1000.0
1000.0]
1806 |
⇆ |
M_56dura_c + M_nadp_c ⇆ M_h_c + M_nadph_c + M_ura_c |
|
|
|
|
|
Reaction |
R_G6PDH2r R_G6PDH2r
|
Glucose 6-phosphate dehydrogenase
[0.0
1000.0]
2539 |
➞ |
M_g6p_c + M_nadp_c ➞ M_6pgl_c + M_h_c + M_nadph_c |
|
|
|
|
|
Reaction |
R_NADPtru R_NADPtru
|
NADP transporter, endoplasmic reticulum
[0.0
1000.0]
|
➞ |
M_nadp_r ➞ M_nadp_c |
|
|
|
|
|
Reaction |
R_G5SADrm R_G5SADrm
|
L glutamate 5 semialdehyde dehydratase reversible mitochondrial
[-1000.0
1000.0]
|
⇆ |
M_glu5sa_m ⇆ M_1pyr5c_m + M_h2o_m + M_h_m |
|
|
|
|
|
Reaction |
R_G3PD2m R_G3PD2m
|
Glycerol-3-phosphate dehydrogenase (FAD), mitochondrial
[0.0
1000.0]
2820 |
➞ |
M_fad_m + M_glyc3p_c ➞ M_dhap_c + M_fadh2_m |
|
|
|
|
|
Reaction |
R_DRPA R_DRPA
|
Deoxyribose-phosphate aldolase
[0.0
1000.0]
|
➞ |
M_2dr5p_c ➞ M_acald_c + M_g3p_c |
|
|
|
|
|
Reaction |
R_NADPHtru R_NADPHtru
|
NADPH transporter, endoplasmic reticulum
[0.0
1000.0]
|
➞ |
M_nadph_c ➞ M_nadph_r |
|
|
|
|
|
Reaction |
R_DRBK R_DRBK
|
Deoxyribokinase
[0.0
1000.0]
64080 |
➞ |
M_atp_c + M_drib_c ➞ M_2dr5p_c + M_adp_c + M_h_c |
|
|
|
|
|
Reaction |
R_DPGase R_DPGase
|
Diphosphoglycerate phosphatase
[0.0
1000.0]
(5224 or 669 or 5223) |
➞ |
M_23dpg_c + M_h2o_c ➞ M_3pg_c + M_pi_c |
|
|
|
|
|
Reaction |
R_G3PD1ir R_G3PD1ir
|
Glycerol 3 phosphate dehydrogenase NAD
[-1000.0
1000.0]
2819 |
⇆ |
M_dhap_c + M_h_c + M_nadh_c ⇆ M_glyc3p_c + M_nad_c |
|
|
|
|
|
Reaction |
R_FUMtm R_FUMtm
|
Fumarate transport, mitochondrial
[-1000.0
1000.0]
1468 |
⇆ |
M_fum_c + M_pi_m ⇆ M_fum_m + M_pi_c |
|
|
|
|
|
Reaction |
R_DPGM R_DPGM
|
Diphosphoglyceromutase
[-1000.0
1000.0]
(5224 or 669 or 5223) |
⇆ |
M_13dpg_c ⇆ M_23dpg_c + M_h_c |
|
|
|
|
|
Reaction |
R_NADNe R_NADNe
|
NAD nucleosidase,extracellular
[0.0
1000.0]
952 |
➞ |
M_h2o_e + M_nad_e ➞ M_adprib_e + M_h_e + M_ncam_e |
|
|
|
|
|
Reaction |
R_FUMm R_FUMm
|
Fumarase mitochondrial
[-1000.0
1000.0]
2271 |
⇆ |
M_fum_m + M_h2o_m ⇆ M_mal__L_m |
|
|
|
|
|
Reaction |
R_FUMTSULtm R_FUMTSULtm
|
Fumarate:thiosulfate antiport, mitochondrial
[-1000.0
1000.0]
1468 |
⇆ |
M_fum_c + M_tsul_m ⇆ M_fum_m + M_tsul_c |
|
|
|
|
|
Reaction |
R_FUMSO3tm R_FUMSO3tm
|
Fumarate:sulfite antiport, mitochondrial
[-1000.0
1000.0]
1468 |
⇆ |
M_fum_c + M_so3_m ⇆ M_fum_m + M_so3_c |
|
|
|
|
|
Reaction |
R_DOPAVESSEC R_DOPAVESSEC
|
Dopamine secretion via secretory vesicle (ATP driven)
[0.0
1000.0]
6571 |
➞ |
2.0 M_atp_c + 3.0 M_dopa_c + 2.0 M_h2o_c ➞ 2.0 M_adp_c + 3.0 M_dopa_e + 2.0 M_h_c + 2.0 M_pi_c |
|
|
|
|
|
Reaction |
R_NADN R_NADN
|
NAD nucleosidase
[0.0
1000.0]
|
➞ |
M_h2o_c + M_nad_c ➞ M_adprib_c + M_h_c + M_ncam_c |
|
|
|
|
|
Reaction |
R_DOPASULT R_DOPASULT
|
Dopamine Sulfotransferase
[0.0
1000.0]
(6817 or 6799) |
➞ |
M_dopa_c + M_paps_c ➞ M_dopasf_c + M_h_c + M_pap_c |
|
|
|
|
|
Reaction |
R_DOPASFt R_DOPASFt
|
Dopamine 3-0-sulfate transport (diffusion)
[0.0
1000.0]
|
➞ |
M_dopasf_c ➞ M_dopasf_e |
|
|
|
|
|
Reaction |
R_DOPAMT R_DOPAMT
|
Dopamine:amet O-methyltransferase
[0.0
1000.0]
1312 |
➞ |
M_amet_c + M_dopa_c ➞ M_3moxtyr_c + M_ahcys_c + M_h_c |
|
|
|
|
|
Reaction |
R_FUMAC R_FUMAC
|
Fumarylacetoacetase
[0.0
1000.0]
2184 |
➞ |
M_4fumacac_c + M_h2o_c ➞ M_acac_c + M_fum_c + M_h_c |
|
|
|
|
|
Reaction |
R_FTHFLi R_FTHFLi
|
Formate-tetrahydrofolate ligase
[0.0
1000.0]
4522 |
➞ |
M_atp_c + M_for_c + M_thf_c ➞ M_10fthf_c + M_adp_c + M_pi_c |
|
|
|
|
|
Reaction |
R_DOPABMO R_DOPABMO
|
Dopamine beta-monooxygenase
[0.0
1000.0]
(26002 or 1621) |
➞ |
M_ascb__L_c + M_dopa_c + M_o2_c ➞ M_dhdascb_c + M_h2o_c + M_nrpphr_c |
|
|
|
|
|
Reaction |
R_NADH2_u10m R_NADH2_u10m
|
NADH dehydrogenase, mitochondrial
[0.0
1000.0]
(51079 and 374291 and 55967 and 7991 and 4536 and 4537 and 4538 and 4539 and 4540 and 4541 and 4535 and 126328 and 4694 and 4695 and 4696 and 4697 and 4698 and 4700 and 4701 and 4702 and 4704 and 4705 and 4706 and 4707 and 4708 and 4709 and 4710 and 4711 and 4712 and 4713 and 4714 and 4715 and 4716 and 4717 and 4718 and 4719 and 4720 and 4722 and 4723 and 4724 and 4725 and 4726 and 4728 and 4729 and 4731) |
➞ |
5.0 M_h_m + M_nadh_m + M_q10_m ➞ 4.0 M_h_c + M_nad_m + M_q10h2_m |
|
|
|
|
|
Reaction |
R_FRUt4 R_FRUt4
|
D-fructose transport via sodium cotransport
[-1000.0
1000.0]
200010 |
⇆ |
M_fru_e + M_na1_e ⇆ M_fru_c + M_na1_c |
|
|
|
|
|
Reaction |
R_MTHFR3 R_MTHFR3
|
5 10 methylenetetrahydrofolatereductase NADPH
[0.0
1000.0]
4524 |
➞ |
2.0 M_h_c + M_mlthf_c + M_nadph_c ➞ M_5mthf_c + M_nadp_c |
|
|
|
|
|
Reaction |
R_FRUt1r R_FRUt1r
|
D-fructose transport in via uniport
[-1000.0
1000.0]
(155184 or 6514 or 66035 or 29988 or 6518) |
⇆ |
M_fru_e ⇆ M_fru_c |
|
|
|
|
|
Reaction |
R_FPGS9m R_FPGS9m
|
Folylpolyglutamate synthetase (10fthf), mitochondrial
[0.0
1000.0]
2356 |
➞ |
M_10fthf6glu_m + M_atp_m + M_glu__L_m ➞ M_10fthf7glu_m + M_adp_m + M_h_m + M_pi_m |
|
|
|
|
|
Reaction |
R_FPGS9 R_FPGS9
|
Folylpolyglutamate synthetase (10fthf)
[0.0
1000.0]
2356 |
➞ |
M_10fthf6glu_c + M_atp_c + M_glu__L_c ➞ M_10fthf7glu_c + M_adp_c + M_h_c + M_pi_c |
|
|
|
|
|
Reaction |
R_FPGS8m R_FPGS8m
|
Folylpolyglutamate synthetase (10fthf), mitochondrial
[0.0
1000.0]
2356 |
➞ |
M_10fthf5glu_m + M_atp_m + M_glu__L_m ➞ M_10fthf6glu_m + M_adp_m + M_h_m + M_pi_m |
|
|
|
|
|
Reaction |
R_DMGtm R_DMGtm
|
Dimethylglycine transport via diffusion (cytosol to mitochondria)
[-1000.0
1000.0]
|
⇆ |
M_dmgly_c ⇆ M_dmgly_m |
|
|
|
|
|
Reaction |
R_DMGDHm R_DMGDHm
|
Dimethylglycine dehydrogenase, mitochondrial
[0.0
1000.0]
29958 |
➞ |
M_dmgly_m + M_fad_m + M_h2o_m ➞ M_fadh2_m + M_fald_m + M_sarcs_m |
|
|
|
|
|
Reaction |
R_DHPR2 R_DHPR2
|
6,7-dihydropteridine reduction
[0.0
1000.0]
|
➞ |
M_5mthf_c + M_dhbpt_c ➞ M_h_c + M_mlthf_c + M_thbpt_c |
|
|
|
|
|
Reaction |
R_FPGS7m R_FPGS7m
|
Folylpolyglutamate synthetase (10fthf), mitochondrial
[0.0
1000.0]
2356 |
➞ |
M_10fthf_m + 4.0 M_atp_m + 4.0 M_glu__L_m ➞ M_10fthf5glu_m + 4.0 M_adp_m + 4.0 M_h_m + 4.0 M_pi_m |
|
|
|
|
|
Reaction |
R_MTHFDm R_MTHFDm
|
Methylenetetrahydrofolate dehydrogenase NADP mitochondrial
[-1000.0
1000.0]
(10797 or 25902) |
⇆ |
M_mlthf_m + M_nadp_m ⇆ M_methf_m + M_nadph_m |
|
|
|
|
|
Reaction |
R_FE2tm R_FE2tm
|
Iron (II) transport
[0.0
1000.0]
|
➞ |
M_fe2_c + M_h_c ➞ M_fe2_m + M_h_m |
|
|
|
|
|
Reaction |
R_DHPM1 R_DHPM1
|
Dihydropyrimidinase (5,6-dihydrouracil)
[0.0
1000.0]
1808 |
➞ |
M_56dura_c + M_h2o_c ➞ M_cala_c + M_h_c |
|
|
|
|
|
Reaction |
R_DHAAt1r R_DHAAt1r
|
Dehydroascorbate transport (uniport)
[-1000.0
1000.0]
6515 |
⇆ |
M_dhdascb_e ⇆ M_dhdascb_c |
|
|
|
|
|
Reaction |
R_FE2t R_FE2t
|
Iron II transport
[0.0
1000.0]
|
➞ |
M_fe2_e ➞ M_fe2_c |
|
|
|
|
|
Reaction |
R_FCLTm R_FCLTm
|
Ferrochelatase mitochondrial
[0.0
1000.0]
2235 |
➞ |
M_fe2_m + M_ppp9_m ➞ 2.0 M_h_m + M_pheme_m |
|
|
|
|
|
Reaction |
R_FBP26 R_FBP26
|
Fructose 2 6 bisphosphate 2 phosphatase
[0.0
1000.0]
(8789 or 5207 or 5208 or 5209 or 5210 or 2203) |
➞ |
M_f26bp_c + M_h2o_c ➞ M_f6p_c + M_pi_c |
|
|
|
|
|
Reaction |
R_DGULND R_DGULND
|
Dehydro-L-gulonate decarboxylase
[-1000.0
1000.0]
|
⇆ |
M_3dhguln_c + M_h_c ⇆ M_co2_c + M_xylu__L_c |
|
|
|
|
|
Reaction |
R_DADA R_DADA
|
Deoxyadenosine deaminase
[0.0
1000.0]
100 |
➞ |
M_dad_2_c + M_h2o_c + M_h_c ➞ M_din_c + M_nh4_c |
|
|
|
|
|
Reaction |
R_MTHFD2m R_MTHFD2m
|
Methylenetetrahydrofolate dehydrogenase (NAD), mitochondrial
[-1000.0
1000.0]
10797 |
⇆ |
M_mlthf_m + M_nad_m ⇆ M_methf_m + M_nadh_m |
|
|
|
|
|
Reaction |
R_CYTK7 R_CYTK7
|
Cytidylate kinase (CMP,UTP)
[-1000.0
1000.0]
51727 |
⇆ |
M_cmp_c + M_utp_c ⇆ M_cdp_c + M_udp_c |
|
|
|
|
|
Reaction |
R_FBP R_FBP
|
Fructose-bisphosphatase
[0.0
1000.0]
(2203 or 8789) |
➞ |
M_fdp_c + M_h2o_c ➞ M_f6p_c + M_pi_c |
|
|
|
|
|
Reaction |
R_MTHFD R_MTHFD
|
Methylenetetrahydrofolate dehydrogenase (NADP)
[-1000.0
1000.0]
4522 |
⇆ |
M_mlthf_c + M_nadp_c ⇆ M_methf_c + M_nadph_c |
|
|
|
|
|
Reaction |
R_FBA2 R_FBA2
|
D Fructose 1 phosphate D glyceraldehyde 3 phosphate lyase
[-1000.0
1000.0]
(226 or 230) |
⇆ |
M_f1p_c ⇆ M_dhap_c + M_glyald_c |
|
|
|
|
|
Reaction |
R_FBA R_FBA
|
Fructose-bisphosphate aldolase
[-1000.0
1000.0]
(226 or 230) |
⇆ |
M_fdp_c ⇆ M_dhap_c + M_g3p_c |
|
|
|
|
|
Reaction |
R_CPK1 R_CPK1
|
Adenylate kinase
[-1000.0
1000.0]
51727 |
⇆ |
M_cmp_c + M_ctp_c ⇆ 2.0 M_cdp_c |
|
|
|
|
|
Reaction |
R_CYTK1 R_CYTK1
|
Cytidylate kinase (CMP)
[-1000.0
1000.0]
51727 |
⇆ |
M_atp_c + M_cmp_c ⇆ M_adp_c + M_cdp_c |
|
|
|
|
|
Reaction |
R_CYTDt R_CYTDt
|
Cytidine facilated transport in cytosol
[-1000.0
1000.0]
2030 |
⇆ |
M_cytd_e ⇆ M_cytd_c |
|
|
|
|
|
Reaction |
R_FATP5t R_FATP5t
|
Fatty acid electroneutral transport
[-1000.0
1000.0]
10998 |
⇆ |
M_arachd_c + M_na1_c ⇆ M_arachd_e + M_na1_e |
|
|
|
|
|
Reaction |
R_CYSTGLUex R_CYSTGLUex
|
L-cystine/L-glutamate exchanger
[0.0
1000.0]
(6520 and 23657) |
➞ |
M_cysi__L_e + M_glu__L_c ➞ M_cysi__L_c + M_glu__L_e |
|
|
|
|
|
Reaction |
R_MTHFCm R_MTHFCm
|
Methenyltetrahydrifikate cyclohydrolase mitochondrial
[-1000.0
1000.0]
(10797 or 25902) |
⇆ |
M_h2o_m + M_methf_m ⇆ M_10fthf_m + M_h_m |
|
|
|
|
|
Reaction |
R_PI4PLC_16_0_18_0 R_PI4PLC_16_0_18_0
|
PI4PLC 16 0 18 0
[0.0
1000.0]
(113026 or 23236 or 84812 or 9651 or 257068 or 89869 or 5330 or 5331 or 5332 or 5333 or 5334 or 5335 or 5336 or 51196 or 23007) |
➞ |
M_h2o_c + M_pail4p_hs_16_0_18_0_c ➞ M_dag_hs_16_0_18_0_c + M_h_c + M_mi14p_c |
|
|
|
|
|
Reaction |
R_FATP3t R_FATP3t
|
Fatty acid electroneutral transport
[-1000.0
1000.0]
376497 |
⇆ |
M_na1_c + M_ocdca_c ⇆ M_na1_e + M_ocdca_e |
|
|
|
|
|
Reaction |
R_FATP2t R_FATP2t
|
Fatty acid electroneutral transport
[-1000.0
1000.0]
376497 |
⇆ |
M_na1_c + M_ocdcea_c ⇆ M_na1_e + M_ocdcea_e |
|
|
|
|
|
Reaction |
R_FATP1t R_FATP1t
|
Fatty acid electroneutral transport
[-1000.0
1000.0]
(11000 or 376497 or 10999) |
⇆ |
M_hdca_c + M_na1_c ⇆ M_hdca_e + M_na1_e |
|
|
|
|
|
Reaction |
R_PIK4_16_0_18_0 R_PIK4_16_0_18_0
|
PIK4 16 0 18 0
[0.0
1000.0]
(5297 or 5298 or 55361) |
➞ |
M_atp_c + M_pail_hs_16_0_18_0_c ➞ M_adp_c + M_h_c + M_pail4p_hs_16_0_18_0_c |
|
|
|
|
|
Reaction |
R_MTHFC R_MTHFC
|
Methenyltetrahydrofolate cyclohydrolase
[-1000.0
1000.0]
4522 |
⇆ |
M_h2o_c + M_methf_c ⇆ M_10fthf_c + M_h_c |
|
|
|
|
|
Reaction |
R_PIPLC_16_0_18_0 R_PIPLC_16_0_18_0
|
PIPLC 16 0 18 0
[0.0
1000.0]
(113026 or 23236 or 84812 or 257068 or 9651 or 89869 or 5330 or 5331 or 5332 or 5333 or 5334 or 5335 or 5336 or 51196 or 23007) |
➞ |
M_h2o_c + M_pail_hs_16_0_18_0_c ➞ M_dag_hs_16_0_18_0_c + M_h_c + M_mi1p__D_c |
|
|
|
|
|
Reaction |
R_CDIPTr_16_0_18_0 R_CDIPTr_16_0_18_0
|
CDIPTr 16 0 18 0
[0.0
1000.0]
10423 |
➞ |
M_cdpdag_hs_16_0_18_0_c + M_inost_c ➞ M_cmp_c + M_h_c + M_pail_hs_16_0_18_0_c |
|
|
|
|
|
Reaction |
R_CDS_16_0_18_0 R_CDS_16_0_18_0
|
CDS 16 0 18 0
[0.0
1000.0]
1040 |
➞ |
M_ctp_c + M_h_c + M_pa_hs_16_0_18_0_c ➞ M_cdpdag_hs_16_0_18_0_c + M_ppi_c |
|
|
|
|
|
Reaction |
R_FAS80COA_L R_FAS80COA_L
|
Fatty acyl CoA synthase n C80CoA lumped reaction
[0.0
1000.0]
2194 |
➞ |
M_accoa_c + 9.0 M_h_c + 3.0 M_malcoa_c + 6.0 M_nadph_c ➞ 3.0 M_co2_c + 3.0 M_coa_c + 3.0 M_h2o_c + 6.0 M_nadp_c + M_occoa_c |
|
|
|
|
|
Reaction |
R_FAS180COA R_FAS180COA
|
Fatty acyl CoA synthase n C180CoA
[0.0
1000.0]
2194 |
➞ |
3.0 M_h_c + M_malcoa_c + 2.0 M_nadph_c + M_pmtcoa_c ➞ M_co2_c + M_coa_c + M_h2o_c + 2.0 M_nadp_c + M_stcoa_c |
|
|
|
|
|
Reaction |
R_FAS160COA R_FAS160COA
|
Fatty acyl CoA synthase n C160CoA
[0.0
1000.0]
2194 |
➞ |
3.0 M_h_c + M_malcoa_c + 2.0 M_nadph_c + M_tdcoa_c ➞ M_co2_c + M_coa_c + M_h2o_c + 2.0 M_nadp_c + M_pmtcoa_c |
|
|
|
|
|
Reaction |
R_LPS2_16_0_18_0 R_LPS2_16_0_18_0
|
LPS2 16 0 18 0
[0.0
1000.0]
4023 |
➞ |
M_dag_hs_16_0_18_0_c + M_h2o_c ➞ M_h_c + M_mag_hs_16_0_c + M_ocdca_c |
|
|
|
|
|
Reaction |
R_MMTSADm R_MMTSADm
|
Malonate-semialdehyde dehydrogenase (acetylating), mitochondrial
[0.0
1000.0]
|
➞ |
M_2mop_m + M_coa_m + M_nad_m ➞ M_h_m + M_mmcoa__R_m + M_nadh_m |
|
|
|
|
|
Reaction |
R_DAGK_hs_16_0_18_0 R_DAGK_hs_16_0_18_0
|
DAGK hs 16 0 18 0
[-1000.0
1000.0]
(1606 or 1607 or 1608 or 1609 or 9162 or 8525 or 8526 or 8527 or 160851) |
⇆ |
M_adp_c + M_h_c + M_pa_hs_16_0_18_0_c ⇆ M_atp_c + M_dag_hs_16_0_18_0_c |
|
|
|
|
|
Reaction |
R_PLA2_2_16_0_18_0 R_PLA2_2_16_0_18_0
|
PLA2 2 16 0 18 0
[0.0
1000.0]
(5320 or 8398) |
➞ |
M_h2o_c + M_pchol_hs_16_0_18_0_c ➞ M_h_c + M_lpchol_hs_16_0_c + M_ocdca_c |
|
|
|
|
|
Reaction |
R_FAS140COA R_FAS140COA
|
Fatty acyl CoA synthase n C140CoA
[0.0
1000.0]
2194 |
➞ |
M_ddcacoa_c + 3.0 M_h_c + M_malcoa_c + 2.0 M_nadph_c ➞ M_co2_c + M_coa_c + M_h2o_c + 2.0 M_nadp_c + M_tdcoa_c |
|
|
|
|
|
Reaction |
R_FAS120COA R_FAS120COA
|
Fatty acyl CoA synthase n C120CoA
[0.0
1000.0]
2194 |
➞ |
M_dcacoa_c + 3.0 M_h_c + M_malcoa_c + 2.0 M_nadph_c ➞ M_co2_c + M_coa_c + M_ddcacoa_c + M_h2o_c + 2.0 M_nadp_c |
|
|
|
|
|
Reaction |
R_FAS100COA R_FAS100COA
|
Fatty acyl CoA synthase n C100CoA
[0.0
1000.0]
2194 |
➞ |
3.0 M_h_c + M_malcoa_c + 2.0 M_nadph_c + M_occoa_c ➞ M_co2_c + M_coa_c + M_dcacoa_c + M_h2o_c + 2.0 M_nadp_c |
|
|
|
|
|
Reaction |
R_FAOXC80 R_FAOXC80
|
Beta oxidation of med/long chain fatty acid
[0.0
1000.0]
(34 or 35) |
➞ |
3.0 M_coa_m + 3.0 M_fad_m + 3.0 M_h2o_m + 3.0 M_nad_m + M_occoa_m ➞ 4.0 M_accoa_m + 3.0 M_fadh2_m + 3.0 M_h_m + 3.0 M_nadh_m |
|
|
|
|
|
Reaction |
R_FAOXC204 R_FAOXC204
|
Beta oxidation of long chain fatty acid
[0.0
1000.0]
(34 or 35) |
➞ |
M_arachdcoa_m + 9.0 M_coa_m + 5.0 M_fad_m + 9.0 M_h2o_m + 9.0 M_nad_m ➞ 10.0 M_accoa_m + 5.0 M_fadh2_m + 9.0 M_h_m + 9.0 M_nadh_m |
|
|
|
|
|
Reaction |
R_FAOXC182806m R_FAOXC182806m
|
Beta oxidation of fatty acid
[0.0
1000.0]
(34 or 35) |
➞ |
5.0 M_coa_m + 3.0 M_fad_m + 5.0 M_h2o_m + M_lnlccoa_m + 5.0 M_nad_m ➞ 5.0 M_accoa_m + 3.0 M_fadh2_m + 5.0 M_h_m + 5.0 M_nadh_m + M_occoa_m |
|
|
|
|
|
Reaction |
R_FAOXC1811603m R_FAOXC1811603m
|
Beta oxidation fatty acid
[0.0
1000.0]
(34 or 35) |
➞ |
5.0 M_coa_m + 4.0 M_fad_m + 5.0 M_h2o_m + 5.0 M_nad_m + M_odecoa_m ➞ 5.0 M_accoa_m + 4.0 M_fadh2_m + 5.0 M_h_m + 5.0 M_nadh_m + M_occoa_m |
|
|
|
|
|
Reaction |
R_FAOXC180 R_FAOXC180
|
Beta oxidation of long chain fatty acid
[0.0
1000.0]
(34 or 35) |
➞ |
M_coa_m + M_fad_m + M_h2o_m + M_nad_m + M_stcoa_m ➞ M_accoa_m + M_fadh2_m + M_h_m + M_nadh_m + M_pmtcoa_m |
|
|
|
|
|
Reaction |
R_FAOXC16080m R_FAOXC16080m
|
Beta oxidation of long chain fatty acid
[0.0
1000.0]
(34 or 35) |
➞ |
4.0 M_coa_m + 4.0 M_fad_m + 4.0 M_h2o_m + 4.0 M_nad_m + M_pmtcoa_m ➞ 4.0 M_accoa_m + 4.0 M_fadh2_m + 4.0 M_h_m + 4.0 M_nadh_m + M_occoa_m |
|
|
|
|
|
Reaction |
R_CEPTC_16_0_18_0 R_CEPTC_16_0_18_0
|
CEPTC 16 0 18 0
[0.0
1000.0]
(56994 or 10390) |
➞ |
M_cdpchol_c + M_dag_hs_16_0_18_0_c ➞ M_cmp_c + M_h_c + M_pchol_hs_16_0_18_0_c |
|
|
|
|
|
Reaction |
R_PSSA1_hs_16_0_18_0 R_PSSA1_hs_16_0_18_0
|
PSSA1 hs 16 0 18 0
[-1000.0
1000.0]
9791 |
⇆ |
M_chol_c + M_ps_hs_16_0_18_0_c ⇆ M_pchol_hs_16_0_18_0_c + M_ser__L_c |
|
|
|
|
|
Reaction |
R_PSSA2_hs_16_0_18_0 R_PSSA2_hs_16_0_18_0
|
PSSA2 hs 16 0 18 0
[-1000.0
1000.0]
81490 |
⇆ |
M_pe_hs_16_0_18_0_c + M_ser__L_c ⇆ M_etha_c + M_ps_hs_16_0_18_0_c |
|
|
|
|
|
Reaction |
R_CEPTE_16_0_18_0 R_CEPTE_16_0_18_0
|
CEPTE 16 0 18 0
[0.0
1000.0]
10390 |
➞ |
M_cdpea_c + M_dag_hs_16_0_18_0_c ➞ M_cmp_c + M_h_c + M_pe_hs_16_0_18_0_c |
|
|
|
|
|
Reaction |
R_PPAP_16_0_18_0 R_PPAP_16_0_18_0
|
PPAP 16 0 18 0
[0.0
1000.0]
(8611 or 8612 or 8613) |
➞ |
M_h2o_c + M_pa_hs_16_0_18_0_c ➞ M_dag_hs_16_0_18_0_c + M_pi_c |
|
|
|
|
|
Reaction |
R_AGPAT1_16_0_18_0 R_AGPAT1_16_0_18_0
|
AGPAT1 16 0 18 0
[0.0
1000.0]
(137964 or 56894 or 10554 or 10555 or 55326 or 56895) |
➞ |
M_alpha_hs_16_0_c + M_stcoa_c ➞ M_coa_c + M_pa_hs_16_0_18_0_c |
|
|
|
|
|
Reaction |
R_PI45PLC_16_0_16_0 R_PI45PLC_16_0_16_0
|
Phosphatidylinositol 4,5-bisphosphate phospholipase C (C16:0, C16:0)
[0.0
1000.0]
(113026 or 23236 or 84812 or 9651 or 257068 or 89869 or 5330 or 5331 or 5332 or 5333 or 5334 or 5335 or 5336 or 51196 or 23007) |
➞ |
M_h2o_c + M_pail45p_hs_16_0_16_0_c ➞ M_dag_hs_16_0_16_0_c + M_h_c + M_mi145p_c |
|
|
|
|
|
Reaction |
R_FAOXC160 R_FAOXC160
|
Beta oxidation of long chain fatty acid
[0.0
1000.0]
(34 or 35) |
➞ |
7.0 M_coa_m + 7.0 M_fad_m + 7.0 M_h2o_m + 7.0 M_nad_m + M_pmtcoa_m ➞ 8.0 M_accoa_m + 7.0 M_fadh2_m + 7.0 M_h_m + 7.0 M_nadh_m |
|
|
|
|
|
Reaction |
R_FALDtm R_FALDtm
|
Formaldehyde transport via diffusion (mitochondrial)
[-1000.0
1000.0]
|
⇆ |
M_fald_m ⇆ M_fald_c |
|
|
|
|
|
Reaction |
R_FALDH R_FALDH
|
Formaldehyde dehydrogenase
[-1000.0
1000.0]
128 |
⇆ |
M_fald_c + M_gthrd_c + M_nad_c ⇆ M_Sfglutth_c + M_h_c + M_nadh_c |
|
|
|
|
|
Reaction |
R_PI345P3P_16_0_16_0 R_PI345P3P_16_0_16_0
|
PI345P3P 16 0 16 0
[0.0
1000.0]
5728 |
➞ |
M_h2o_c + M_pail345p_hs_16_0_16_0_c ➞ M_pail45p_hs_16_0_16_0_c + M_pi_c |
|
|
|
|
|
Reaction |
R_PI4P5K_16_0_16_0 R_PI4P5K_16_0_16_0
|
PI4P5K 16 0 16 0
[0.0
1000.0]
(200576 or 23396 or 8394 or 8395 or 8396 or 5305 or 79837) |
➞ |
M_atp_c + M_pail45p_hs_16_0_16_0_c ➞ M_adp_c + M_h_c + M_pail345p_hs_16_0_16_0_c |
|
|
|
|
|
Reaction |
R_MMSAD3m R_MMSAD3m
|
Methylmalonate-semialdehyde dehydrogenase (acylating)
[0.0
1000.0]
4329 |
➞ |
M_coa_m + M_msa_m + M_nad_m ➞ M_accoa_m + M_co2_m + M_nadh_m |
|
|
|
|
|
Reaction |
R_PI34P5K_16_0_16_0 R_PI34P5K_16_0_16_0
|
PI34P5K 16 0 16 0
[0.0
1000.0]
(8394 or 8395 or 23396) |
➞ |
M_atp_c + M_pail34p_hs_16_0_16_0_c ➞ M_adp_c + M_h_c + M_pail345p_hs_16_0_16_0_c |
|
|
|
|
|
Reaction |
R_PI4P3K_16_0_16_0 R_PI4P3K_16_0_16_0
|
PI4P3K 16 0 16 0
[0.0
1000.0]
(5286 or 5287 or 5288 or 5290 or 5291 or 5293 or 5294 or 23533 or 5296 or 10870 or 8503 or 5295) |
➞ |
M_atp_c + M_pail4p_hs_16_0_16_0_c ➞ M_adp_c + M_h_c + M_pail34p_hs_16_0_16_0_c |
|
|
|
|
|
Reaction |
R_PI4PLC_16_0_16_0 R_PI4PLC_16_0_16_0
|
Phosphatidylinositol 4-phosphate phospholipase C (C16:0,C16:0)
[0.0
1000.0]
(113026 or 23236 or 84812 or 9651 or 257068 or 89869 or 5330 or 5331 or 5332 or 5333 or 5334 or 5335 or 5336 or 51196 or 23007) |
➞ |
M_h2o_c + M_pail4p_hs_16_0_16_0_c ➞ M_dag_hs_16_0_16_0_c + M_h_c + M_mi14p_c |
|
|
|
|
|
Reaction |
R_PIK4_16_0_16_0 R_PIK4_16_0_16_0
|
Phosphatidylinositol 4-kinase (C16:0,C16:0)
[0.0
1000.0]
(5297 or 5298 or 55361) |
➞ |
M_atp_c + M_pail_hs_16_0_16_0_c ➞ M_adp_c + M_h_c + M_pail4p_hs_16_0_16_0_c |
|
|
|
|
|
Reaction |
R_FACOAL204 R_FACOAL204
|
Fatty-acid--CoA ligase
[0.0
1000.0]
(2180 or 2181 or 2182) |
➞ |
M_arachd_c + M_atp_c + M_coa_c ➞ M_amp_c + M_arachdcoa_c + M_ppi_c |
|
|
|
|
|
Reaction |
R_FACOAL1821 R_FACOAL1821
|
Linoleic acid:CoA ligase (AMP-forming)
[-1000.0
1000.0]
2180 |
⇆ |
M_atp_c + M_coa_c + M_lnlc_c ⇆ M_amp_c + M_lnlccoa_c + M_ppi_c |
|
|
|
|
|
Reaction |
R_FACOAL181 R_FACOAL181
|
Fatty acid CoA ligase octadecenoate
[0.0
1000.0]
(2180 or 2181) |
➞ |
M_atp_c + M_coa_c + M_ocdcea_c ➞ M_amp_c + M_odecoa_c + M_ppi_c |
|
|
|
|
|
Reaction |
R_FACOAL180 R_FACOAL180
|
Fatty acid CoA ligase octadecanoate
[0.0
1000.0]
(2180 or 2181 or 51703) |
➞ |
M_atp_c + M_coa_c + M_ocdca_c ➞ M_amp_c + M_ppi_c + M_stcoa_c |
|
|
|
|
|
Reaction |
R_PIPLC_16_0_16_0 R_PIPLC_16_0_16_0
|
Phosphatidylinositol phospholipase C (C16:0,C16:0)
[0.0
1000.0]
(113026 or 23236 or 84812 or 257068 or 9651 or 89869 or 5330 or 5331 or 5332 or 5333 or 5334 or 5335 or 5336 or 51196 or 23007) |
➞ |
M_h2o_c + M_pail_hs_16_0_16_0_c ➞ M_dag_hs_16_0_16_0_c + M_h_c + M_mi1p__D_c |
|
|
|
|
|
Reaction |
R_CDIPTr_16_0_16_0 R_CDIPTr_16_0_16_0
|
Phosphatidylinositol synthase (Homo sapiens, C16:0, C16:0)
[0.0
1000.0]
10423 |
➞ |
M_cdpdag_hs_16_0_16_0_c + M_inost_c ➞ M_cmp_c + M_h_c + M_pail_hs_16_0_16_0_c |
|
|
|
|
|
Reaction |
R_CDS_16_0_16_0 R_CDS_16_0_16_0
|
Phosphatidate cytidylyltransferase (C16:0, C16:0)
[0.0
1000.0]
1040 |
➞ |
M_ctp_c + M_h_c + M_pa_hs_16_0_16_0_c ➞ M_cdpdag_hs_16_0_16_0_c + M_ppi_c |
|
|
|
|
|
Reaction |
R_LPS2_16_0_16_0 R_LPS2_16_0_16_0
|
LPS2 16 0 16 0
[0.0
1000.0]
4023 |
➞ |
M_dag_hs_16_0_16_0_c + M_h2o_c ➞ M_h_c + M_hdca_c + M_mag_hs_16_0_c |
|
|
|
|
|
Reaction |
R_DAGK_hs_16_0_16_0 R_DAGK_hs_16_0_16_0
|
Diacylglycerol phosphate kinase (homo sapiens, C16:0, C16:0)
[-1000.0
1000.0]
(1606 or 1607 or 1608 or 1609 or 9162 or 8525 or 8526 or 8527 or 160851) |
⇆ |
M_adp_c + M_h_c + M_pa_hs_16_0_16_0_c ⇆ M_atp_c + M_dag_hs_16_0_16_0_c |
|
|
|
|
|
Reaction |
R_FACOAL160 R_FACOAL160
|
Fatty acid CoA ligase hexadecanoate
[0.0
1000.0]
(2180 or 2181 or 51703) |
➞ |
M_atp_c + M_coa_c + M_hdca_c ➞ M_amp_c + M_pmtcoa_c + M_ppi_c |
|
|
|
|
|
Reaction |
R_ETFQO R_ETFQO
|
Electron transfer flavoprotein-ubiquinone oxidoreductase
[0.0
1000.0]
2110 |
➞ |
M_etfrd_m + M_q10_m ➞ M_etfox_m + M_q10h2_m |
|
|
|
|
|
Reaction |
R_ETF R_ETF
|
Electron transfer flavoprotein
[0.0
1000.0]
(2108 and 2109) |
➞ |
M_etfox_m + M_fadh2_m ➞ M_etfrd_m + M_fad_m |
|
|
|
|
|
Reaction |
R_ESTSULT R_ESTSULT
|
Estrogen sulfotransferase
[0.0
1000.0]
6817 |
➞ |
M_estrone_c + M_paps_c ➞ M_estrones_c + M_h_c + M_pap_c |
|
|
|
|
|
Reaction |
R_MMMm R_MMMm
|
Methylmalonyl-CoA mutase
[-1000.0
1000.0]
4594 |
⇆ |
M_mmcoa__R_m ⇆ M_succoa_m |
|
|
|
|
|
Reaction |
R_GTMLTe R_GTMLTe
|
G-glutamyltransferase (e)
[0.0
1000.0]
2678 |
➞ |
M_ala__L_c + M_gthrd_c ➞ M_cgly_e + M_gluala_e |
|
|
|
|
|
Reaction |
R_EX_ins_e R_EX_ins_e
|
Inosine exchange
[-1000.0
1000.0]
|
⇆ |
M_ins_e ⇆ |
|
|
|
|
|
Reaction |
R_EX_inost_e R_EX_inost_e
|
Myo-Inositol exchange
[-1000.0
1000.0]
|
⇆ |
M_inost_e ⇆ |
|
|
|
|
|
Reaction |
R_GTHS R_GTHS
|
Glutathione synthetase
[0.0
1000.0]
2937 |
➞ |
M_atp_c + M_glucys_c + M_gly_c ➞ M_adp_c + M_gthrd_c + M_h_c + M_pi_c |
|
|
|
|
|
Reaction |
R_PLA2_2_16_0_16_0 R_PLA2_2_16_0_16_0
|
Phospholipase A2 (C16:0,C16:0)
[0.0
1000.0]
(5320 or 8398) |
➞ |
M_h2o_c + M_pchol_hs_16_0_16_0_c ➞ M_h_c + M_hdca_c + M_lpchol_hs_16_0_c |
|
|
|
|
|
Reaction |
R_CEPTC_16_0_16_0 R_CEPTC_16_0_16_0
|
Choline phosphotransferase (C16:0, C16:0)
[0.0
1000.0]
(56994 or 10390) |
➞ |
M_cdpchol_c + M_dag_hs_16_0_16_0_c ➞ M_cmp_c + M_h_c + M_pchol_hs_16_0_16_0_c |
|
|
|
|
|
Reaction |
R_PSSA1_hs_16_0_16_0 R_PSSA1_hs_16_0_16_0
|
PSSA1 hs 16 0 16 0
[-1000.0
1000.0]
9791 |
⇆ |
M_chol_c + M_ps_hs_16_0_16_0_c ⇆ M_pchol_hs_16_0_16_0_c + M_ser__L_c |
|
|
|
|
|
Reaction |
R_PSSA2_hs_16_0_16_0 R_PSSA2_hs_16_0_16_0
|
PSSA2 hs 16 0 16 0
[-1000.0
1000.0]
81490 |
⇆ |
M_pe_hs_16_0_16_0_c + M_ser__L_c ⇆ M_etha_c + M_ps_hs_16_0_16_0_c |
|
|
|
|
|
Reaction |
R_GTHRDtr R_GTHRDtr
|
Glutathione transport via diffusion
[-1000.0
1000.0]
|
⇆ |
M_gthrd_c ⇆ M_gthrd_r |
|
|
|
|
|
Reaction |
R_CEPTE_16_0_16_0 R_CEPTE_16_0_16_0
|
Ethanolamine phosphotransferase (C16:0,C16:0)
[0.0
1000.0]
10390 |
➞ |
M_cdpea_c + M_dag_hs_16_0_16_0_c ➞ M_cmp_c + M_h_c + M_pe_hs_16_0_16_0_c |
|
|
|
|
|
Reaction |
R_PPAP_16_0_16_0 R_PPAP_16_0_16_0
|
Phosphatidic acid phosphatase (C16:0, C16:0)
[0.0
1000.0]
(8611 or 8612 or 8613) |
➞ |
M_h2o_c + M_pa_hs_16_0_16_0_c ➞ M_dag_hs_16_0_16_0_c + M_pi_c |
|
|
|
|
|
Reaction |
R_ARGt5r R_ARGt5r
|
ARGtiDF
[-1000.0
1000.0]
6541 |
⇆ |
M_arg__L_e ⇆ M_arg__L_c |
|
|
|
|
|
Reaction |
R_AGPAT1_16_0_16_0 R_AGPAT1_16_0_16_0
|
AGPAT1 16 0 16 0
[0.0
1000.0]
(137964 or 56894 or 10554 or 10555 or 55326 or 56895) |
➞ |
M_alpha_hs_16_0_c + M_pmtcoa_c ➞ M_coa_c + M_pa_hs_16_0_16_0_c |
|
|
|
|
|
Reaction |
R_GTHPm R_GTHPm
|
Glutathione peroxidase mitochondria
[-1000.0
1000.0]
(2879 or 10935) |
⇆ |
2.0 M_gthrd_m + M_h2o2_m ⇆ M_gthox_m + 2.0 M_h2o_m |
|
|
|
|
|
Reaction |
R_LPASE_20_4 R_LPASE_20_4
|
LPASE 20 4
[0.0
1000.0]
(5321 or 1178 or 29124) |
➞ |
M_h2o_c + M_lpchol_hs_20_4_c ➞ M_arachd_c + M_g3pc_c + M_h_c |
|
|
|
|
|
Reaction |
R_LPS3_hs_20_4 R_LPS3_hs_20_4
|
LPS3 hs 20 4
[0.0
1000.0]
11343 |
➞ |
M_h2o_c + M_mag_hs_20_4_c ➞ M_arachd_c + M_glyc_c + M_h_c |
|
|
|
|
|
Reaction |
R_GPAM_hs_20_4 R_GPAM_hs_20_4
|
GPAM hs 20 4
[0.0
1000.0]
57678 |
➞ |
M_arachdcoa_c + M_glyc3p_c ➞ M_alpha_hs_20_4_c + M_coa_c |
|
|
|
|
|
Reaction |
R_GTHPe R_GTHPe
|
Glutathione peroxidase
[-1000.0
1000.0]
(257202 or 2878) |
⇆ |
2.0 M_gthrd_e + M_h2o2_e ⇆ M_gthox_e + 2.0 M_h2o_e |
|
|
|
|
|
Reaction |
R_GTHPi R_GTHPi
|
Glutathione peridoxase
[-1000.0
1000.0]
(2876 or 5052 or 7001 or 2879) |
⇆ |
2.0 M_gthrd_c + M_h2o2_c ⇆ M_gthox_c + 2.0 M_h2o_c |
|
|
|
|
|
Reaction |
R_ARGSS R_ARGSS
|
Argininosuccinate synthase
[0.0
1000.0]
445 |
➞ |
M_asp__L_c + M_atp_c + M_citr__L_c ➞ M_amp_c + M_argsuc_c + M_h_c + M_ppi_c |
|
|
|
|
|
Reaction |
R_ARGSL R_ARGSL
|
Argininosuccinate lyase
[-1000.0
1000.0]
435 |
⇆ |
M_argsuc_c ⇆ M_arg__L_c + M_fum_c |
|
|
|
|
|
Reaction |
R_GTHOm R_GTHOm
|
Glutathione oxidoreductase
[0.0
1000.0]
2936 |
➞ |
M_gthox_m + M_h_m + M_nadph_m ➞ 2.0 M_gthrd_m + M_nadp_m |
|
|
|
|
|
Reaction |
R_CYSTA R_CYSTA
|
Cysteine transaminase
[-1000.0
1000.0]
2805 |
⇆ |
M_akg_c + M_cys__L_c ⇆ M_glu__L_c + M_mercppyr_c |
|
|
|
|
|
Reaction |
R_GTHOr R_GTHOr
|
Glutathione oxidoreductase
[0.0
1000.0]
2936 |
➞ |
M_gthox_c + M_h_c + M_nadph_c ➞ 2.0 M_gthrd_c + M_nadp_c |
|
|
|
|
|
Reaction |
R_CYSGLTH R_CYSGLTH
|
Glutathione:cystine oxidoreductase
[-1000.0
1000.0]
|
⇆ |
M_cysi__L_c + 2.0 M_gthrd_c ⇆ 2.0 M_cys__L_c + M_gthox_c |
|
|
|
|
|
Reaction |
R_CYOR_u10m R_CYOR_u10m
|
Ubiquinol-6 cytochrome c reductase, Complex III
[0.0
1000.0]
(1537 and 29796 and 4519 and 27089 and 7381 and 7384 and 7385 and 7386 and 7388 and 10975) |
➞ |
2.0 M_ficytC_m + 2.0 M_h_m + M_q10h2_m ➞ 2.0 M_focytC_m + 4.0 M_h_c + M_q10_m |
|
|
|
|
|
Reaction |
R_ARGN R_ARGN
|
Arginase
[0.0
1000.0]
383 |
➞ |
M_arg__L_c + M_h2o_c ➞ M_orn_c + M_urea_c |
|
|
|
|
|
Reaction |
R_ARACHDtr R_ARACHDtr
|
Intracellular transport
[-1000.0
1000.0]
|
⇆ |
M_arachd_c ⇆ M_arachd_r |
|
|
|
|
|
Reaction |
R_ARACHDt2 R_ARACHDt2
|
Fatty acid transport via diffusion
[-1000.0
1000.0]
|
⇆ |
M_arachd_e ⇆ M_arachd_c |
|
|
|
|
|
Reaction |
R_CYOOm2 R_CYOOm2
|
Cytochromecoxidase,mitochondrialComplexIV
[0.0
1000.0]
(4512 and 4513 and 1346 and 1347 and 9167 and 1349 and 1350 and 9377 and 1351 and 125965 and 1345 and 4514 and 1329 and 341947 and 1327 and 170712 and 1337 and 1339 and 1340 and 84701) |
➞ |
4.0 M_focytC_m + 8.0 M_h_m + M_o2_m ➞ 4.0 M_ficytC_m + 2.0 M_h2o_m + 4.0 M_h_c |
|
|
|
|
|
Reaction |
R_GSNt R_GSNt
|
Guanosine facilated transport in cytosol
[-1000.0
1000.0]
2030 |
⇆ |
M_gsn_e ⇆ M_gsn_c |
|
|
|
|
|
Reaction |
R_CYANtm R_CYANtm
|
Cyanide transport via diffusion (mitochondrial)
[-1000.0
1000.0]
|
⇆ |
M_cyan_c ⇆ M_cyan_m |
|
|
|
|
|
Reaction |
R_CYANt R_CYANt
|
Cyanide transport via diffusion (extracellular to cytosol)
[-1000.0
1000.0]
|
⇆ |
M_cyan_e ⇆ M_cyan_c |
|
|
|
|
|
Reaction |
R_APAT2rm R_APAT2rm
|
3-Aminopropanoate:2-oxoglutarate aminotransferase (m)
[-1000.0
1000.0]
18 |
⇆ |
M_akg_m + M_ala_B_m ⇆ M_glu__L_m + M_msa_m |
|
|
|
|
|
Reaction |
R_AMPTASECGe R_AMPTASECGe
|
Alanyl aminopeptidase (cys-gly) (e)
[0.0
1000.0]
290 |
➞ |
M_cgly_e + M_h2o_e ➞ M_cys__L_e + M_gly_e |
|
|
|
|
|
Reaction |
R_GPDDA1 R_GPDDA1
|
Glycerophosphodiester phosphodiesterase (Glycerophosphocholine)
[0.0
1000.0]
|
➞ |
M_g3pc_c + M_h2o_c ➞ M_chol_c + M_glyc3p_c + M_h_c |
|
|
|
|
|
Reaction |
R_AMPDA R_AMPDA
|
Adenosine monophosphate deaminase
[0.0
1000.0]
271 |
➞ |
M_amp_c + M_h2o_c + M_h_c ➞ M_imp_c + M_nh4_c |
|
|
|
|
|
Reaction |
R_CYANSTm R_CYANSTm
|
Cyanide sulfurtransferase, mitochondrial
[0.0
1000.0]
7263 |
➞ |
M_cyan_m + M_tsul_m ➞ M_h_m + M_so3_m + M_tcynt_m |
|
|
|
|
|
Reaction |
R_GND R_GND
|
Phosphogluconate dehydrogenase
[0.0
1000.0]
5226 |
➞ |
M_6pgc_c + M_nadp_c ➞ M_co2_c + M_nadph_c + M_ru5p__D_c |
|
|
|
|
|
Reaction |
R_CSm R_CSm
|
Citrate synthase
[0.0
1000.0]
1431 |
➞ |
M_accoa_m + M_h2o_m + M_oaa_m ➞ M_cit_m + M_coa_m + M_h_m |
|
|
|
|
|
Reaction |
R_CSNATr R_CSNATr
|
Carnitine O acetyltransferase
[-1000.0
1000.0]
|
⇆ |
M_accoa_c + M_crn_c ⇆ M_acrn_c + M_coa_c |
|
|
|
|
|
Reaction |
R_GMPR R_GMPR
|
GMP reductase
[0.0
1000.0]
(51292 or 2766) |
➞ |
M_gmp_c + 2.0 M_h_c + M_nadph_c ➞ M_imp_c + M_nadp_c + M_nh4_c |
|
|
|
|
|
Reaction |
R_ALR3 R_ALR3
|
Aldose reductase (acetol)
[0.0
1000.0]
(231 or 8574 or 10327) |
➞ |
M_acetol_c + M_h_c + M_nadph_c ➞ M_12ppd__S_c + M_nadp_c |
|
|
|
|
|
Reaction |
R_CRNtuNa R_CRNtuNa
|
L-carnitine inward transport by Na+ symport
[-1000.0
1000.0]
6584 |
⇆ |
M_crn_e + M_na1_e ⇆ M_crn_c + M_na1_c |
|
|
|
|
|
Reaction |
R_ALR2 R_ALR2
|
Aldose reductase (methylglyoxal)
[0.0
1000.0]
(10327 or 8574 or 231) |
➞ |
M_h_c + M_mthgxl_c + M_nadph_c ➞ M_acetol_c + M_nadp_c |
|
|
|
|
|
Reaction |
R_CRNt_copy1 R_CRNt_copy1
|
L carnitine reversible transport
[-1000.0
1000.0]
6583 |
⇆ |
M_crn_e ⇆ M_crn_c |
|
|
|
|
|
Reaction |
R_ALR R_ALR
|
Aldose reductase
[0.0
1000.0]
231 |
➞ |
M_h2o_c + M_mthgxl_c + M_nadp_c ➞ 2.0 M_h_c + M_nadph_c + M_pyr_c |
|
|
|
|
|
Reaction |
R_GLYOX R_GLYOX
|
Hydroxyacylglutathione hydrolase
[0.0
1000.0]
3029 |
➞ |
M_h2o_c + M_lgt__S_c ➞ M_gthrd_c + M_h_c + M_lac__D_c |
|
|
|
|
|
Reaction |
R_ALOX52 R_ALOX52
|
Arachidonate 5-lipoxygenase
[0.0
1000.0]
240 |
➞ |
M_5HPET_c ➞ M_h2o_c + M_leuktrA4_c |
|
|
|
|
|
Reaction |
R_ALOX5 R_ALOX5
|
Arachidonate 5-lipoxygenase
[0.0
1000.0]
240 |
➞ |
M_arachd_c + M_o2_c ➞ M_5HPET_c |
|
|
|
|
|
Reaction |
R_CRNtim R_CRNtim
|
L carnitine transport out of mitochondria via diffusion
[0.0
1000.0]
788 |
➞ |
M_crn_m ➞ M_crn_c |
|
|
|
|
|
Reaction |
R_CRNt_copy2 R_CRNt_copy2
|
L carnitine reversible transport
[-1000.0
1000.0]
6584 |
⇆ |
M_crn_e ⇆ M_crn_c |
|
|
|
|
|
Reaction |
R_ALOX15 R_ALOX15
|
Arachidonate 15-lipoxygenase
[0.0
1000.0]
(246 or 247) |
➞ |
M_arachd_c + M_o2_c ➞ M_15HPET_c |
|
|
|
|
|
Reaction |
R_GLYK R_GLYK
|
Glycerol kinase
[0.0
1000.0]
(2712 or 2710) |
➞ |
M_atp_c + M_glyc_c ➞ M_adp_c + M_glyc3p_c + M_h_c |
|
|
|
|
|
Reaction |
R_ALOX12 R_ALOX12
|
Arachidonate 12-lipoxygenase
[0.0
1000.0]
239 |
➞ |
M_arachd_c + M_o2_c ➞ M_12HPET_c |
|
|
|
|
|
Reaction |
R_CREATt4_2_r R_CREATt4_2_r
|
CREATt4 LPAREN 2 RPAREN r
[-1000.0
1000.0]
(6537 or 6535) |
⇆ |
M_creat_e + 2.0 M_na1_e ⇆ M_creat_c + 2.0 M_na1_c |
|
|
|
|
|
Reaction |
R_GLYBt4_2_r R_GLYBt4_2_r
|
GLYBt4 LPAREN 2 RPAREN r
[-1000.0
1000.0]
6539 |
⇆ |
M_glyb_e + 2.0 M_na1_e ⇆ M_glyb_c + 2.0 M_na1_c |
|
|
|
|
|
Reaction |
R_ALDD2y R_ALDD2y
|
Aldehyde dehydrogenase (acetaldehyde, NADP)
[0.0
1000.0]
(224 or 223) |
➞ |
M_acald_c + M_h2o_c + M_nadp_c ➞ M_ac_c + 2.0 M_h_c + M_nadph_c |
|
|
|
|
|
Reaction |
R_ALDD2x R_ALDD2x
|
Aldehyde dehydrogenase (acetaldehyde, NAD)
[0.0
1000.0]
(224 or 216 or 223) |
➞ |
M_acald_c + M_h2o_c + M_nad_c ➞ M_ac_c + 2.0 M_h_c + M_nadh_c |
|
|
|
|
|
Reaction |
R_GLYAMDTRc R_GLYAMDTRc
|
Glycine amidinotransferase (c)
[-1000.0
1000.0]
2628 |
⇆ |
M_arg__L_c + M_gly_c ⇆ M_gudac_c + M_orn_c |
|
|
|
|
|
Reaction |
R_ALDD20x R_ALDD20x
|
Aldehyde dehydrogenase (indole-3-acetaldehyde, NAD)
[0.0
1000.0]
(216 or 224 or 223) |
➞ |
M_h2o_c + M_id3acald_c + M_nad_c ➞ 2.0 M_h_c + M_ind3ac_c + M_nadh_c |
|
|
|
|
|
Reaction |
R_ALDD19x_P R_ALDD19x_P
|
Aldehyde dehydrogenase (phenylacetaldehyde, NADP)
[0.0
1000.0]
(218 or 220 or 221 or 222) |
➞ |
M_h2o_c + M_nadp_c + M_pacald_c ➞ 2.0 M_h_c + M_nadph_c + M_pac_c |
|
|
|
|
|
Reaction |
R_CPPPGO R_CPPPGO
|
Coproporphyrinogen oxidase (O2 required)
[0.0
1000.0]
1371 |
➞ |
M_cpppg3_c + 2.0 M_h_c + M_o2_c ➞ 2.0 M_co2_c + 2.0 M_h2o_c + M_pppg9_c |
|
|
|
|
|
Reaction |
R_GLUtr R_GLUtr
|
Intracellular transport
[-1000.0
1000.0]
|
⇆ |
M_glu__L_c ⇆ M_glu__L_r |
|
|
|
|
|
Reaction |
R_COt R_COt
|
CO transporter via diffusion
[-1000.0
1000.0]
|
⇆ |
M_co_c ⇆ M_co_e |
|
|
|
|
|
Reaction |
R_ALDD19xr R_ALDD19xr
|
Aldehyde dehydrogenase (phenylacetaldehyde, NAD)
[0.0
1000.0]
(218 or 220 or 221 or 222) |
➞ |
M_h2o_c + M_nad_c + M_pacald_c ➞ 2.0 M_h_c + M_nadh_c + M_pac_c |
|
|
|
|
|
Reaction |
R_CO2t R_CO2t
|
CO2 transporter via diffusion
[-1000.0
1000.0]
|
⇆ |
M_co2_e ⇆ M_co2_c |
|
|
|
|
|
Reaction |
R_LCARS R_LCARS
|
Lacaldehyde reductase (S-propane-1,2-diol forming)
[-1000.0
0.0]
((126 and 124) or (125 and 124) or (125 and 126) or 284273 or 131 or 130 or 128 or 125 or 126 or 127 or 124 or 137872) |
⇆ |
M_h_c + M_lald__L_c + M_nadh_c ⇆ M_12ppd__S_c + M_nad_c |
|
|
|
|
|
Reaction |
R_GLUt7l R_GLUt7l
|
Glutamate transport, lysosomal
[0.0
1000.0]
|
➞ |
M_glu__L_l ➞ M_glu__L_c |
|
|
|
|
|
Reaction |
R_ALCD21_D R_ALCD21_D
|
Alcohol dehydrogenase (D-1,2-propanediol)
[-1000.0
1000.0]
((126 and 124) or (125 and 124) or (125 and 126) or 284273 or 131 or 130 or 128 or 125 or 126 or 127 or 124 or 137872) |
⇆ |
M_12ppd__R_c + M_nad_c ⇆ M_h_c + M_lald__D_c + M_nadh_c |
|
|
|
|
|
Reaction |
R_CLOHtex2 R_CLOHtex2
|
Chloride transport via hydroxide countertransport (2:1)
[-1000.0
1000.0]
65010 |
⇆ |
2.0 M_cl_e + M_oh1_c ⇆ 2.0 M_cl_c + M_oh1_e |
|
|
|
|
|
Reaction |
R_GLUt6 R_GLUt6
|
Glutamate transport via Na, H symport and K antiport
[0.0
1000.0]
6505 |
➞ |
M_glu__L_e + M_h_e + M_k_c + 3.0 M_na1_e ➞ M_glu__L_c + M_h_c + M_k_e + 3.0 M_na1_c |
|
|
|
|
|
Reaction |
R_CITt4_4 R_CITt4_4
|
Citrate transport via sodium symport
[-1000.0
1000.0]
284111 |
⇆ |
M_cit_e + 4.0 M_na1_e ⇆ M_cit_c + 4.0 M_na1_c |
|
|
|
|
|
Reaction |
R_CITt4_2 R_CITt4_2
|
Citrate transport via sodium symport
[-1000.0
1000.0]
9058 |
⇆ |
M_cit_e + 2.0 M_na1_e ⇆ M_cit_c + 2.0 M_na1_c |
|
|
|
|
|
Reaction |
R_CITRtm R_CITRtm
|
Citrulline transport via diffusion, mitochondria
[-1000.0
1000.0]
10166 |
⇆ |
M_citr__L_m ⇆ M_citr__L_c |
|
|
|
|
|
Reaction |
R_CHOLtu R_CHOLtu
|
Choline uniport
[-1000.0
1000.0]
(6584 or 6582) |
⇆ |
M_chol_e ⇆ M_chol_c |
|
|
|
|
|
Reaction |
R_ALCD1 R_ALCD1
|
Alcohol dehydrogenase (methanol)
[-1000.0
1000.0]
((126 and 124) or (125 and 124) or (125 and 126) or 284273 or 131 or 130 or 128 or 125 or 126 or 127 or 124 or 137872) |
⇆ |
M_meoh_c + M_nad_c ⇆ M_fald_c + M_h_c + M_nadh_c |
|
|
|
|
|
Reaction |
R_ALATA_L R_ALATA_L
|
L-alanine transaminase
[-1000.0
1000.0]
(84706 or 2875) |
⇆ |
M_akg_c + M_ala__L_c ⇆ M_glu__L_c + M_pyr_c |
|
|
|
|
|
Reaction |
R_GLUTCOADHm R_GLUTCOADHm
|
Glutaryl-CoA dehydrogenase (mitochondria)
[0.0
1000.0]
2639 |
➞ |
M_fad_m + M_glutcoa_m + M_h_m ➞ M_b2coa_m + M_co2_m + M_fadh2_m |
|
|
|
|
|
Reaction |
R_ALASm R_ALASm
|
5 aminolevulinate synthase
[0.0
1000.0]
(23464 or 211 or 212) |
➞ |
M_gly_m + M_h_m + M_succoa_m ➞ M_5aop_m + M_co2_m + M_coa_m |
|
|
|
|
|
Reaction |
R_CHOLt4 R_CHOLt4
|
Choline, sodium cotransport
[-1000.0
1000.0]
60482 |
⇆ |
M_chol_e + M_na1_e ⇆ M_chol_c + M_na1_c |
|
|
|
|
|
Reaction |
R_CHLPCTD R_CHLPCTD
|
Choline phosphate cytididyltransferase
[0.0
1000.0]
(5130 or 9468) |
➞ |
M_cholp_c + M_ctp_c + M_h_c ➞ M_cdpchol_c + M_ppi_c |
|
|
|
|
|
Reaction |
R_ALAGLNexR R_ALAGLNexR
|
L-alanine/glutamine reversible exchange
[-1000.0
1000.0]
(6520 and 56301) |
⇆ |
M_ala__L_e + M_gln__L_c ⇆ M_ala__L_c + M_gln__L_e |
|
|
|
|
|
Reaction |
R_GLUPRT R_GLUPRT
|
Glutamine phosphoribosyldiphosphate amidotransferase
[0.0
1000.0]
5471 |
➞ |
M_gln__L_c + M_h2o_c + M_prpp_c ➞ M_glu__L_c + M_ppi_c + M_pram_c |
|
|
|
|
|
Reaction |
R_AKGDm R_AKGDm
|
2-oxoglutarate dehydrogenase
[0.0
1000.0]
((1738 and 8050) and 1743 and 4967) |
➞ |
M_akg_m + M_coa_m + M_nad_m ➞ M_co2_m + M_nadh_m + M_succoa_m |
|
|
|
|
|
Reaction |
R_CGMPt R_CGMPt
|
CGMP transport (ATP-dependent)
[0.0
1000.0]
(10257 or 10057) |
➞ |
M_35cgmp_c + M_atp_c + M_h2o_c ➞ M_35cgmp_e + M_adp_c + M_h_c + M_pi_c |
|
|
|
|
|
Reaction |
R_CBPSam R_CBPSam
|
Carbamoyl-phosphate synthase (ammonia) (mitochondria
[0.0
1000.0]
1373 |
➞ |
2.0 M_atp_m + M_hco3_m + M_nh4_m ➞ 2.0 M_adp_m + M_cbp_m + 2.0 M_h_m + M_pi_m |
|
|
|
|
|
Reaction |
R_AIRCr R_AIRCr
|
Phosphoribosylaminoimidazole carboxylase
[-1000.0
1000.0]
10606 |
⇆ |
M_air_c + M_co2_c ⇆ M_5aizc_c + M_h_c |
|
|
|
|
|
Reaction |
R_GLUNm R_GLUNm
|
Glutaminase (mitochondrial)
[0.0
1000.0]
(2744 or 27165) |
➞ |
M_gln__L_m + M_h2o_m ➞ M_glu__L_m + M_nh4_m |
|
|
|
|
|
Reaction |
R_AICART R_AICART
|
Phosphoribosylaminoimidazolecarboxamide formyltransferase
[-1000.0
1000.0]
471 |
⇆ |
M_10fthf_c + M_aicar_c ⇆ M_fprica_c + M_thf_c |
|
|
|
|
|
Reaction |
R_CATp R_CATp
|
Catalase A peroxisomal
[0.0
1000.0]
847 |
➞ |
2.0 M_h2o2_x ➞ 2.0 M_h2o_x + M_o2_x |
|
|
|
|
|
Reaction |
R_CATm R_CATm
|
Catalase
[0.0
1000.0]
847 |
➞ |
2.0 M_h2o2_m ➞ 2.0 M_h2o_m + M_o2_m |
|
|
|
|
|
Reaction |
R_GDHm R_GDHm
|
Glutamate dehydrogenase, mitochondria
[-1000.0
1000.0]
2746 |
⇆ |
M_glu__L_m + M_h2o_m + M_nad_m ⇆ M_akg_m + M_h_m + M_nadh_m + M_nh4_m |
|
|
|
|
|
Reaction |
R_CAATPS R_CAATPS
|
CAATPS
[0.0
1000.0]
(490 or 493) |
➞ |
M_atp_c + 2.0 M_ca2_c + M_h2o_c ➞ M_adp_c + 2.0 M_ca2_e + M_h_e + M_pi_c |
|
|
|
|
|
Reaction |
R_C204CRNt R_C204CRNt
|
Arachidonic acid transport into the mitochondria
[0.0
1000.0]
|
➞ |
M_arachdcrn_c ➞ M_arachdcrn_m |
|
|
|
|
|
Reaction |
R_C204CPT2 R_C204CPT2
|
Arachidonic acid transport into the mitochondria
[0.0
1000.0]
1376 |
➞ |
M_arachdcrn_m + M_coa_m ➞ M_arachdcoa_m + M_crn_m |
|
|
|
|
|
Reaction |
R_C204CPT1 R_C204CPT1
|
Carnitine C20:4 transferase
[0.0
1000.0]
1374 |
➞ |
M_arachdcoa_c + M_crn_c ➞ M_arachdcrn_c + M_coa_c |
|
|
|
|
|
Reaction |
R_C181CRNt R_C181CRNt
|
C181 transport into the mitochondria
[0.0
1000.0]
788 |
➞ |
M_odecrn_c ➞ M_odecrn_m |
|
|
|
|
|
Reaction |
R_AHCi R_AHCi
|
Adenosylhomocysteinase
[-1000.0
1000.0]
191 |
⇆ |
M_ahcys_c + M_h2o_c ⇆ M_adn_c + M_hcys__L_c |
|
|
|
|
|
Reaction |
R_ADSS R_ADSS
|
Adenylosuccinate synthase
[0.0
1000.0]
122622 |
➞ |
M_asp__L_c + M_gtp_c + M_imp_c ➞ M_dcamp_c + M_gdp_c + 2.0 M_h_c + M_pi_c |
|
|
|
|
|
Reaction |
R_C181CPT2 R_C181CPT2
|
Carnitine octadecenoyl transferase
[0.0
1000.0]
1376 |
➞ |
M_coa_m + M_odecrn_m ➞ M_crn_m + M_odecoa_m |
|
|
|
|
|
Reaction |
R_C181CPT1 R_C181CPT1
|
Carnitine octadecenoyl transferase
[0.0
1000.0]
1374 |
➞ |
M_crn_c + M_odecoa_c ➞ M_coa_c + M_odecrn_c |
|
|
|
|
|
Reaction |
R_ADSL2r R_ADSL2r
|
Adenylosuccinate lyase
[0.0
1000.0]
158 |
➞ |
M_25aics_c ➞ M_aicar_c + M_fum_c |
|
|
|
|
|
Reaction |
R_GLUDC R_GLUDC
|
Glutamate Decarboxylase
[0.0
1000.0]
(2571 or 2572) |
➞ |
M_glu__L_c + M_h_c ➞ M_4abut_c + M_co2_c |
|
|
|
|
|
Reaction |
R_ADSL1r R_ADSL1r
|
Adenylsuccinate lyase
[0.0
1000.0]
158 |
➞ |
M_dcamp_c ➞ M_amp_c + M_fum_c |
|
|
|
|
|
Reaction |
R_C180CRNt R_C180CRNt
|
C180 transport into the mitochondria
[0.0
1000.0]
788 |
➞ |
M_stcrn_c ➞ M_stcrn_m |
|
|
|
|
|
Reaction |
R_C180CPT2 R_C180CPT2
|
Carnitine O-stearoyl transferase
[0.0
1000.0]
1376 |
➞ |
M_coa_m + M_stcrn_m ➞ M_crn_m + M_stcoa_m |
|
|
|
|
|
Reaction |
R_GLUCYS R_GLUCYS
|
Gamma-glutamylcysteine synthetase
[0.0
1000.0]
(2729 and 2730) |
➞ |
M_atp_c + M_cys__L_c + M_glu__L_c ➞ M_adp_c + M_glucys_c + M_h_c + M_pi_c |
|
|
|
|
|
Reaction |
R_C180CPT1 R_C180CPT1
|
Carnitine O-stearoyl transferase
[0.0
1000.0]
1374 |
➞ |
M_crn_c + M_stcoa_c ➞ M_coa_c + M_stcrn_c |
|
|
|
|
|
Reaction |
R_ADSK R_ADSK
|
Adenylyl-sulfate kinase
[0.0
1000.0]
(9060 or 9061) |
➞ |
M_aps_c + M_atp_c ➞ M_adp_c + M_h_c + M_paps_c |
|
|
|
|
|
Reaction |
R_GLPASE2 R_GLPASE2
|
Glycogen phosphorylase (amyls -> glc-D)
[0.0
1000.0]
(5834 or 5836 or 5837) |
➞ |
M_glygn3_c + 7.0 M_h2o_c ➞ M_Tyr_ggn_c + 7.0 M_glc__D_c |
|
|
|
|
|
Reaction |
R_C160CRNt R_C160CRNt
|
C160 transport into the mitochondria
[0.0
1000.0]
788 |
➞ |
M_pmtcrn_c ➞ M_pmtcrn_m |
|
|
|
|
|
Reaction |
R_C160CPT2 R_C160CPT2
|
C160 transport into the mitochondria
[0.0
1000.0]
1376 |
➞ |
M_coa_m + M_pmtcrn_m ➞ M_crn_m + M_pmtcoa_m |
|
|
|
|
|
Reaction |
R_GLPASE1 R_GLPASE1
|
Glycogen phosphorylase (glygn2 -> dxtrn)
[0.0
1000.0]
(5834 or 5836 or 5837) |
➞ |
M_glygn2_c + 3.0 M_pi_c ➞ M_dxtrn_c + 3.0 M_g1p_c |
|
|
|
|
|
Reaction |
R_GLNtm R_GLNtm
|
L-glutamine transport via electroneutral transporter
[0.0
1000.0]
|
➞ |
M_gln__L_c ➞ M_gln__L_m |
|
|
|
|
|
Reaction |
R_C160CPT1 R_C160CPT1
|
Carnitine O-palmitoyltransferase
[0.0
1000.0]
1374 |
➞ |
M_crn_c + M_pmtcoa_c ➞ M_coa_c + M_pmtcrn_c |
|
|
|
|
|
Reaction |
R_ADRNLPVESSEC R_ADRNLPVESSEC
|
Adrenaline secretion via secretory vesicle (ATP driven)
[0.0
1000.0]
6571 |
➞ |
3.0 M_adrnl_c + 2.0 M_atp_c + 2.0 M_h2o_c ➞ 2.0 M_adp_c + 3.0 M_adrnl_e + 2.0 M_h_c + 2.0 M_pi_c |
|
|
|
|
|
Reaction |
R_GLNS R_GLNS
|
Glutamine synthetase
[0.0
1000.0]
2752 |
➞ |
M_atp_c + M_glu__L_c + M_nh4_c ➞ M_adp_c + M_gln__L_c + M_h_c + M_pi_c |
|
|
|
|
|
Reaction |
R_ADPT R_ADPT
|
Adenine phosphoribosyltransferase
[0.0
1000.0]
353 |
➞ |
M_ade_c + M_prpp_c ➞ M_amp_c + M_ppi_c |
|
|
|
|
|
Reaction |
R_BPNT R_BPNT
|
3',5'-bisphosphate nucleotidase
[0.0
1000.0]
10380 |
➞ |
M_h2o_c + M_pap_c ➞ M_amp_c + M_pi_c |
|
|
|
|
|
Reaction |
R_BILIRUBt2 R_BILIRUBt2
|
Bilirubin transport via bicarbonate countertransport
[-1000.0
1000.0]
10599 |
⇆ |
M_bilirub_e + M_hco3_c ⇆ M_bilirub_c + M_hco3_e |
|
|
|
|
|
Reaction |
R_ADPRDP R_ADPRDP
|
ADPribose diphosphatase
[0.0
1000.0]
11164 |
➞ |
M_adprib_c + M_h2o_c ➞ M_amp_c + 2.0 M_h_c + M_r5p_c |
|
|
|
|
|
Reaction |
R_BILIRED R_BILIRED
|
Nad(p)h biliverdin reductase
[0.0
1000.0]
(644 or 645) |
➞ |
M_biliverd_c + M_h_c + M_nadph_c ➞ M_bilirub_c + M_nadp_c |
|
|
|
|
|
Reaction |
R_5HOXINDACTOX R_5HOXINDACTOX
|
5-Hydroxyindoleacetaldehyde:NAD+ oxidoreductase
[0.0
1000.0]
(224 or 216 or 223) |
➞ |
M_5hoxindact_c + M_h2o_c + M_nad_c ➞ M_5hoxindoa_c + 2.0 M_h_c + M_nadh_c |
|
|
|
|
|
Reaction |
R_BHMT R_BHMT
|
Betaine-homocysteine S-methyltransferase
[0.0
1000.0]
(635 or 23743) |
➞ |
M_glyb_c + M_hcys__L_c ➞ M_dmgly_c + M_met__L_c |
|
|
|
|
|
Reaction |
R_BALAtmr R_BALAtmr
|
Beta-alanine transport, mitochondria
[-1000.0
1000.0]
|
⇆ |
M_ala_B_c ⇆ M_ala_B_m |
|
|
|
|
|
Reaction |
R_ADNt R_ADNt
|
Adenosine facilated transport in cytosol
[-1000.0
1000.0]
2030 |
⇆ |
M_adn_e ⇆ M_adn_c |
|
|
|
|
|
Reaction |
R_ADNK1 R_ADNK1
|
Adenosine kinase
[0.0
1000.0]
132 |
➞ |
M_adn_c + M_atp_c ➞ M_adp_c + M_amp_c + M_h_c |
|
|
|
|
|
Reaction |
R_ADNCYC R_ADNCYC
|
Adenylate cyclase
[0.0
1000.0]
(112 or 109 or 111) |
➞ |
M_atp_c ➞ M_camp_c + M_ppi_c |
|
|
|
|
|
Reaction |
R_ADK3m R_ADK3m
|
Adentylate kinase GTP
[-1000.0
1000.0]
50808 |
⇆ |
M_amp_m + M_gtp_m ⇆ M_adp_m + M_gdp_m |
|
|
|
|
|
Reaction |
R_ADK1m R_ADK1m
|
Adenylate kinase mitochondrial
[-1000.0
1000.0]
204 |
⇆ |
M_amp_m + M_atp_m ⇆ 2.0 M_adp_m |
|
|
|
|
|
Reaction |
R_ADK1 R_ADK1
|
Adenylate kinase
[-1000.0
1000.0]
203 |
⇆ |
M_amp_c + M_atp_c ⇆ 2.0 M_adp_c |
|
|
|
|
|
Reaction |
R_ADEt R_ADEt
|
Adenine transport via diffusion
[-1000.0
1000.0]
3177 |
⇆ |
M_ade_e ⇆ M_ade_c |
|
|
|
|
|
Reaction |
R_ATPS4m R_ATPS4m
|
ATP synthase (four protons for one ATP)
[0.0
1000.0]
(513 and 514 and 515 and 516 and 517 and 518 and 10632 and 521 and 522 and 10476 and 9551 and 498 and 4905 and 506 and 509) |
➞ |
M_adp_m + 4.0 M_h_c + M_pi_m ➞ M_atp_m + M_h2o_m + 3.0 M_h_m |
|
|
|
|
|
Reaction |
R_ATPH2e R_ATPH2e
|
ATP diphosphohydrolase
[0.0
1000.0]
(953 or 954 or 955 or 956 or 957) |
➞ |
M_adp_e + M_h2o_e ➞ M_amp_e + M_h_e + M_pi_e |
|
|
|
|
|
Reaction |
R_ASPt6 R_ASPt6
|
L-aspartate transport via Na, H symport and K antiport
[-1000.0
1000.0]
6505 |
⇆ |
M_asp__L_e + M_h_e + M_k_c + 3.0 M_na1_e ⇆ M_asp__L_c + M_h_c + M_k_e + 3.0 M_na1_c |
|
|
|
|
|
Reaction |
R_ASPTAm R_ASPTAm
|
Aspartate transaminase
[-1000.0
1000.0]
2806 |
⇆ |
M_akg_m + M_asp__L_m ⇆ M_glu__L_m + M_oaa_m |
|
|
|
|
|
Reaction |
R_ADAe R_ADAe
|
Adenosine deaminase, extracellular
[0.0
1000.0]
100 |
➞ |
M_adn_e + M_h2o_e + M_h_e ➞ M_ins_e + M_nh4_e |
|
|
|
|
|
Reaction |
R_ASPTA R_ASPTA
|
Aspartate transaminase
[-1000.0
1000.0]
2805 |
⇆ |
M_akg_c + M_asp__L_c ⇆ M_glu__L_c + M_oaa_c |
|
|
|
|
|
Reaction |
R_5HLTDL R_5HLTDL
|
5-Hydroxy-L-tryptophan decarboxy-lyase
[0.0
1000.0]
1644 |
➞ |
M_5htrp_c + M_h_c ➞ M_co2_c + M_srtn_c |
|
|
|
|
|
Reaction |
R_ASNtm R_ASNtm
|
L-asparagine transport, mitochondrial
[0.0
1000.0]
|
➞ |
M_asn__L_c ➞ M_asn__L_m |
|
|
|
|
|
Reaction |
R_ASNSERNaEx R_ASNSERNaEx
|
L-serine/L-asparagine Na-dependent exchange (Asn-L in)
[0.0
1000.0]
6510 |
➞ |
M_asn__L_e + M_na1_e + M_ser__L_c ➞ M_asn__L_c + M_na1_c + M_ser__L_e |
|
|
|
|
|
Reaction |
R_ADA R_ADA
|
Adenosine deaminase
[0.0
1000.0]
100 |
➞ |
M_adn_c + M_h2o_c + M_h_c ➞ M_ins_c + M_nh4_c |
|
|
|
|
|
Reaction |
R_ACt2r R_ACt2r
|
Acetate reversible transport via proton symport
[-1000.0
1000.0]
|
⇆ |
M_ac_e + M_h_e ⇆ M_ac_c + M_h_c |
|
|
|
|
|
Reaction |
R_ACSOMT R_ACSOMT
|
S-Adenosyl-L-methionine:N-acetylserotonin O-methyltransferase
[0.0
1000.0]
438 |
➞ |
M_5hoxindoa_c + M_amet_c ➞ M_5moxact_c + M_ahcys_c + M_h_c |
|
|
|
|
|
Reaction |
R_ACS R_ACS
|
Acetyl-CoA synthetase
[0.0
1000.0]
55902 |
➞ |
M_ac_c + M_atp_c + M_coa_c ➞ M_accoa_c + M_amp_c + M_ppi_c |
|
|
|
|
|
Reaction |
R_ASNNm R_ASNNm
|
L-asparaginase (mitochondrial)
[0.0
1000.0]
80150 |
➞ |
M_asn__L_m + M_h2o_m ➞ M_asp__L_m + M_nh4_m |
|
|
|
|
|
Reaction |
R_5AOPtm R_5AOPtm
|
5 Aminolevulinate mitochondrial transport
[-1000.0
1000.0]
|
⇆ |
M_5aop_c ⇆ M_5aop_m |
|
|
|
|
|
Reaction |
R_ASNALANaEx R_ASNALANaEx
|
L-alanine/L-asparagine Na-dependent exchange (Asn-L in)
[0.0
1000.0]
6510 |
➞ |
M_ala__L_c + M_asn__L_e + M_na1_e ➞ M_ala__L_e + M_asn__L_c + M_na1_c |
|
|
|
|
|
Reaction |
R_ACONTm R_ACONTm
|
Aconitate hydratase
[-1000.0
1000.0]
50 |
⇆ |
M_cit_m ⇆ M_icit_m |
|
|
|
|
|
Reaction |
R_4NPHte R_4NPHte
|
Xenobiotic transport
[-1000.0
1000.0]
|
⇆ |
M_4nph_e ⇆ M_4nph_c |
|
|
|
|
|
Reaction |
R_ACONT R_ACONT
|
Aconitate hydratase
[-1000.0
1000.0]
48 |
⇆ |
M_cit_c ⇆ M_icit_c |
|
|
|
|
|
Reaction |
R_ASCBt4 R_ASCBt4
|
L-ascorbate transport via proton symport
[-1000.0
1000.0]
9962 |
⇆ |
M_ascb__L_e + M_na1_e ⇆ M_ascb__L_c + M_na1_c |
|
|
|
|
|
Reaction |
R_ASCBt R_ASCBt
|
L-ascorbate transport via facilitated diffusion
[-1000.0
1000.0]
|
⇆ |
M_ascb__L_e ⇆ M_ascb__L_c |
|
|
|
|
|
Reaction |
R_4NPHSULT R_4NPHSULT
|
4-Nitrophenol Sulfotransferase
[0.0
1000.0]
(6817 or 6799) |
➞ |
M_4nph_c + M_paps_c ➞ M_4nphsf_c + M_h_c + M_pap_c |
|
|
|
|
|
Reaction |
R_ACOAD9m R_ACOAD9m
|
2-methylacyl-coa dehydrogenase, 2-Methylprop-2-enoyl-CoA forming
[0.0
1000.0]
(27034 or 34) |
➞ |
M_fad_m + M_ibcoa_m ➞ M_2mp2coa_m + M_fadh2_m |
|
|
|
|
|
Reaction |
R_ACOAD8m R_ACOAD8m
|
Isovaleryl-coa dehydrogenase
[0.0
1000.0]
3712 |
➞ |
M_fad_m + M_ivcoa_m ➞ M_3mb2coa_m + M_fadh2_m |
|
|
|
|
|
Reaction |
R_4NPHSFte R_4NPHSFte
|
Xenobiotic transport
[-1000.0
1000.0]
|
⇆ |
M_4nphsf_e ⇆ M_4nphsf_c |
|
|
|
|
|
Reaction |
R_ACOAD10m R_ACOAD10m
|
2-methylacyl-coa dehydrogenase, trans-2-Methylbut-2-enoyl-CoA forming
[0.0
1000.0]
(34 or 36) |
➞ |
M_2mbcoa_m + M_fad_m ➞ M_2mb2coa_m + M_fadh2_m |
|
|
|
|
|
Reaction |
R_EX_hxan_e R_EX_hxan_e
|
Hypoxanthine exchange
[-1000.0
1000.0]
|
⇆ |
M_hxan_e ⇆ |
|
|
|
|
|
Reaction |
R_4MOPt2im R_4MOPt2im
|
4-methyl-2-oxopentanoate mitochondrial transport via proton symport
[0.0
1000.0]
|
➞ |
M_4mop_c + M_h_c ➞ M_4mop_m + M_h_m |
|
|
|
|
|
Reaction |
R_4HOXPACDOX_NADP R_4HOXPACDOX_NADP
|
4HOXPACDOX LPAREN NADP RPAREN
[-1000.0
1000.0]
(218 or 220 or 221 or 222) |
⇆ |
M_4hoxpacd_c + M_h2o_c + M_nadp_c ⇆ M_4hphac_c + 2.0 M_h_c + M_nadph_c |
|
|
|
|
|
Reaction |
R_EX_hista_e R_EX_hista_e
|
Histamine exchange
[-1000.0
1000.0]
|
⇆ |
M_hista_e ⇆ |
|
|
|
|
|
Reaction |
R_EX_his__L_e R_EX_his__L_e
|
L-Histidine exchange
[-1000.0
1000.0]
|
⇆ |
M_his__L_e ⇆ |
|
|
|
|
|
Reaction |
R_ACITL R_ACITL
|
ATP-Citrate lyase
[0.0
1000.0]
47 |
➞ |
M_atp_c + M_cit_c + M_coa_c ➞ M_accoa_c + M_adp_c + M_oaa_c + M_pi_c |
|
|
|
|
|
Reaction |
R_4ABUTtm R_4ABUTtm
|
4 aminobutanoate mitochondrial transport via diffusion
[-1000.0
1000.0]
|
⇆ |
M_4abut_c ⇆ M_4abut_m |
|
|
|
|
|
Reaction |
R_ACCOAC R_ACCOAC
|
Acetyl-CoA carboxylase
[0.0
1000.0]
(32 or 31) |
➞ |
M_accoa_c + M_atp_c + M_hco3_c ➞ M_adp_c + M_h_c + M_malcoa_c + M_pi_c |
|
|
|
|
|
Reaction |
R_ACACT1m R_ACACT1m
|
Acetyl CoA C acetyltransferase mitochondrial
[-1000.0
1000.0]
(3032 and 3030 and 38) |
⇆ |
2.0 M_accoa_m ⇆ M_aacoa_m + M_coa_m |
|
|
|
|
|
Reaction |
R_ACACT1r_copy1 R_ACACT1r_copy1
|
Acetyl-CoA C-acetyltransferase
[-1000.0
1000.0]
39 |
⇆ |
2.0 M_accoa_c ⇆ M_aacoa_c + M_coa_c |
|
|
|
|
|
Reaction |
R_ACACT10m R_ACACT10m
|
Acetyl-CoA C-acyltransferase
[-1000.0
1000.0]
38 |
⇆ |
M_2maacoa_m + M_coa_m ⇆ M_accoa_m + M_ppcoa_m |
|
|
|
|
|
Reaction |
R_EX_hdca_e R_EX_hdca_e
|
Hexadecanoate (n-C16:0) exchange
[-1000.0
1000.0]
|
⇆ |
M_hdca_e ⇆ |
|
|
|
|
|
Reaction |
R_EX_hco3_e R_EX_hco3_e
|
EX hco3 LPAREN e RPAREN
[-1000.0
1000.0]
|
⇆ |
M_hco3_e ⇆ |
|
|
|
|
|
Reaction |
R_EX_h2o2_e R_EX_h2o2_e
|
Hydrogen peroxide exchange
[-1000.0
1000.0]
|
⇆ |
M_h2o2_e ⇆ |
|
|
|
|
|
Reaction |
R_EX_h2o_e R_EX_h2o_e
|
H2O exchange
[-1000.0
1000.0]
|
⇆ |
M_h2o_e ⇆ |
|
|
|
|
|
Reaction |
R_ACACT1r_copy2 R_ACACT1r_copy2
|
Acetyl-CoA C-acetyltransferase
[-1000.0
1000.0]
39 |
⇆ |
2.0 M_accoa_c ⇆ M_aacoa_c + M_coa_c |
|
|
|
|
|
Reaction |
R_ABTArm R_ABTArm
|
4-aminobutyrate transaminase, reversible (mitochondrial)
[-1000.0
1000.0]
18 |
⇆ |
M_4abut_m + M_akg_m ⇆ M_glu__L_m + M_sucsal_m |
|
|
|
|
|
Reaction |
R_EX_h_e R_EX_h_e
|
H+ exchange
[-1000.0
1000.0]
|
⇆ |
M_h_e ⇆ |
|
|
|
|
|
Reaction |
R_EX_gthrd_e R_EX_gthrd_e
|
Reduced glutathione exchange
[-1000.0
1000.0]
|
⇆ |
M_gthrd_e ⇆ |
|
|
|
|
|
Reaction |
R_AATA R_AATA
|
2 aminoadipate transaminase
[-1000.0
0.0]
51166 |
⇆ |
M_2oxoadp_c + M_glu__L_c ⇆ M_L2aadp_c + M_akg_c |
|
|
|
|
|
Reaction |
R_42A12BOOX R_42A12BOOX
|
4-(2-Aminoethyl)-1,2-benzenediol:oxygen oxidoreductase(deaminating)(flavin-containing)
[0.0
1000.0]
(4128 or 4129) |
➞ |
M_dopa_c + M_h2o_c + M_o2_c ➞ M_34dhpac_c + M_h2o2_c + M_nh4_c |
|
|
|
|
|
Reaction |
R_AASAD3m R_AASAD3m
|
L-aminoadipate-semialdehyde dehydrogenase (NADH), mitochondrial
[0.0
1000.0]
|
➞ |
M_L2aadp6sa_m + M_h2o_m + M_nad_m ➞ M_L2aadp_m + 2.0 M_h_m + M_nadh_m |
|
|
|
|
|
Reaction |
R_3MOXTYROX R_3MOXTYROX
|
3-Methoxytyramine:oxygen oxidoreductase (deaminating)
[0.0
1000.0]
(4128 or 4129) |
➞ |
M_3moxtyr_c + M_h2o_c + M_o2_c ➞ M_3mox4hpac_c + M_h2o2_c + M_nh4_c |
|
|
|
|
|
Reaction |
R_AACOAT R_AACOAT
|
Acetoacetyl-CoA:acetate CoA-transferase
[-1000.0
1000.0]
65985 |
⇆ |
M_acac_c + M_atp_c + M_coa_c ⇆ M_aacoa_c + M_amp_c + M_ppi_c |
|
|
|
|
|
Reaction |
R_5MTHFt2 R_5MTHFt2
|
5-methyltetrahydrofolate transport via anion exchange
[-1000.0
1000.0]
6573 |
⇆ |
M_5mthf_e + M_oh1_c ⇆ M_5mthf_c + M_oh1_e |
|
|
|
|
|
Reaction |
R_5MTHFt R_5MTHFt
|
5-Methyltetrahydrofolate transport via receptor binding and protolysis
[-1000.0
1000.0]
2348 |
⇆ |
M_5mthf_e ⇆ M_5mthf_c |
|
|
|
|
|
Reaction |
R_5HOXINOXDA R_5HOXINOXDA
|
5-Hydroxytryptamine:oxygen oxidoreductase(deaminating)(flavin-containing)
[0.0
1000.0]
(4128 or 4129) |
➞ |
M_h2o_c + M_o2_c + M_srtn_c ➞ M_5hoxindact_c + M_h2o2_c + M_nh4_c |
|
|
|
|
|
Reaction |
R_MMEm R_MMEm
|
Methylmalonyl-CoA epimerase/racemase
[-1000.0
1000.0]
84693 |
⇆ |
M_mmcoa__R_m ⇆ M_mmcoa__S_m |
|
|
|
|
|
Reaction |
R_MI4PP R_MI4PP
|
1D-myo-Inositol 4-phosphate phosphohydrolase
[0.0
1000.0]
3612 |
➞ |
M_h2o_c + M_mi4p__D_c ➞ M_inost_c + M_pi_c |
|
|
|
|
|
Reaction |
R_3MOPt2im R_3MOPt2im
|
3-Methyl-2-oxopentanoate mitochondrial transport via proton symport
[0.0
1000.0]
|
➞ |
M_3mop_c + M_h_c ➞ M_3mop_m + M_h_m |
|
|
|
|
|
Reaction |
R_MI1PP R_MI1PP
|
Myo-inositol 1-phosphatase
[0.0
1000.0]
3612 |
➞ |
M_h2o_c + M_mi1p__D_c ➞ M_inost_c + M_pi_c |
|
|
|
|
|
Reaction |
R_3MOBt2im R_3MOBt2im
|
3-methyl-2-oxobutanoate mitochondrial transport via proton symport
[0.0
1000.0]
|
➞ |
M_3mob_c + M_h_c ➞ M_3mob_m + M_h_m |
|
|
|
|
|
Reaction |
R_3M4HDXPAC R_3M4HDXPAC
|
3-Methoxy-4-hydroxyphenylacetaldehyde:NAD+ oxidoreductase
[-1000.0
1000.0]
(218 or 220 or 221 or 222) |
⇆ |
M_3mox4hpac_c + M_h2o_c + M_nad_c ⇆ 2.0 M_h_c + M_homoval_c + M_nadh_c |
|
|
|
|
|
Reaction |
R_3HLYTCL R_3HLYTCL
|
3-Hydroxy-L-tyrosine carboxy-lyase
[0.0
1000.0]
1644 |
➞ |
M_34dhphe_c + M_h_c ➞ M_co2_c + M_dopa_c |
|
|
|
|
|
Reaction |
R_MI14PP R_MI14PP
|
D-myo-Inositol-1,4-bisphosphate 1-phosphohydrolase
[0.0
1000.0]
3628 |
➞ |
M_h2o_c + M_mi14p_c ➞ M_mi4p__D_c + M_pi_c |
|
|
|
|
|
Reaction |
R_HOXG R_HOXG
|
Heme oxygenase 1
[0.0
1000.0]
(3162 or 3163) |
➞ |
5.0 M_h_c + 3.0 M_nadph_c + 3.0 M_o2_c + M_pheme_c ➞ M_biliverd_c + M_co_c + M_fe2_c + 3.0 M_h2o_c + 3.0 M_nadp_c |
|
|
|
|
|
Reaction |
R_3HBCOAHLm R_3HBCOAHLm
|
3-hydroxyisobutyryl-CoA hydrolase, mitochondrial
[0.0
1000.0]
|
➞ |
M_3hibutcoa_m + M_h2o_m ➞ M_3hmp_m + M_coa_m + M_h_m |
|
|
|
|
|
Reaction |
R_MI145PP R_MI145PP
|
D-myo-Inositol-1,4,5-trisphosphate 5-phosphohydrolase
[0.0
1000.0]
(3632 or 3633 or 3635) |
➞ |
M_h2o_c + M_mi145p_c ➞ M_mi14p_c + M_pi_c |
|
|
|
|
|
Reaction |
R_34HPPOR R_34HPPOR
|
4 Hydroxyphenylpyruvateoxygen oxidoreductase
[0.0
1000.0]
3242 |
➞ |
M_34hpp_c + M_o2_c ➞ M_co2_c + M_hgentis_c |
|
|
|
|
|
Reaction |
R_MGSA2 R_MGSA2
|
Methyglyoxylate synthase 2 (from g3p)
[0.0
1000.0]
|
➞ |
M_g3p_c ➞ M_mthgxl_c + M_pi_c |
|
|
|
|
|
Reaction |
R_MGSA R_MGSA
|
Methylglyoxal synthase
[0.0
1000.0]
|
➞ |
M_dhap_c ➞ M_mthgxl_c + M_pi_c |
|
|
|
|
|
Reaction |
R_HMGLm R_HMGLm
|
Hydroxymethylglutaryl-CoA lyase
[0.0
1000.0]
3155 |
➞ |
M_hmgcoa_m ➞ M_acac_m + M_accoa_m |
|
|
|
|
|
Reaction |
R_34DHALDD R_34DHALDD
|
Aldehyde dehydrogenase 3 4 dihydroxyphenylacetaldehyde NAD
[0.0
1000.0]
(218 or 220 or 221 or 222) |
➞ |
M_34dhpac_c + M_h2o_c + M_nad_c ➞ M_34dhpha_c + 2.0 M_h_c + M_nadh_c |
|
|
|
|
|
Reaction |
R_HMBS R_HMBS
|
Hydroxymethylbilane synthase
[0.0
1000.0]
3145 |
➞ |
M_h2o_c + 4.0 M_ppbng_c ➞ M_hmbil_c + 4.0 M_nh4_c |
|
|
|
|
|
Reaction |
R_HIStiDF R_HIStiDF
|
L-histidine transport via diffusion (extracellular to cytosol)
[0.0
1000.0]
55089 |
➞ |
M_his__L_e ➞ M_his__L_c |
|
|
|
|
|
Reaction |
R_HISt4 R_HISt4
|
L-histidine transport in via sodium symport
[0.0
1000.0]
(11254 or 54407) |
➞ |
M_his__L_e + M_na1_e ➞ M_his__L_c + M_na1_c |
|
|
|
|
|
Reaction |
R_HISTAVESSEC R_HISTAVESSEC
|
Histamine secretion via secretory vesicle (ATP driven)
[0.0
1000.0]
6571 |
➞ |
2.0 M_atp_c + 2.0 M_h2o_c + 3.0 M_hista_c ➞ 2.0 M_adp_c + 2.0 M_h_c + 3.0 M_hista_e + 2.0 M_pi_c |
|
|
|
|
|
Reaction |
R_HISDC R_HISDC
|
Histidine decarboxylase
[0.0
1000.0]
(3067 or 1644) |
➞ |
M_h_c + M_his__L_c ➞ M_co2_c + M_hista_c |
|
|
|
|
|
Reaction |
R_MGCHrm R_MGCHrm
|
Methylglutaconyl-coa hydratase
[-1000.0
1000.0]
549 |
⇆ |
M_3mgcoa_m + M_h2o_m ⇆ M_hmgcoa_m |
|
|
|
|
|
Reaction |
R_METtec R_METtec
|
L-methionine transport via diffusion (extracellular to cytosol)
[-1000.0
1000.0]
(8501 or 124935) |
⇆ |
M_met__L_e ⇆ M_met__L_c |
|
|
|
|
|
Reaction |
R_METt4 R_METt4
|
L-methionine transport in via sodium symport
[-1000.0
1000.0]
(6584 or 81539 or 11254 or 54407) |
⇆ |
M_met__L_e + M_na1_e ⇆ M_met__L_c + M_na1_c |
|
|
|
|
|
Reaction |
R_METLEUex R_METLEUex
|
Methionine/Leucine exchange (Met in)
[-1000.0
1000.0]
(6520 and 8140) |
⇆ |
M_leu__L_c + M_met__L_e ⇆ M_leu__L_e + M_met__L_c |
|
|
|
|
|
Reaction |
R_METAT R_METAT
|
Methionine adenosyltransferase
[0.0
1000.0]
((27430 and 4144) or 4143) |
➞ |
M_atp_c + M_h2o_c + M_met__L_c ➞ M_amet_c + M_pi_c + M_ppi_c |
|
|
|
|
|
Reaction |
R_34DHPHAMT R_34DHPHAMT
|
3,4-Dihydroxyphenylacetate:amet O-methyltransferase
[0.0
1000.0]
1312 |
➞ |
M_34dhpha_c + M_amet_c ➞ M_ahcys_c + M_h_c + M_homoval_c |
|
|
|
|
|
Reaction |
R_ME2m R_ME2m
|
Malic enzyme NADP mitochondrial
[0.0
1000.0]
4200 |
➞ |
M_mal__L_m + M_nadp_m ➞ M_co2_m + M_nadph_m + M_pyr_m |
|
|
|
|
|
Reaction |
R_ME1m R_ME1m
|
Malic enzyme NAD mitochondrial
[0.0
1000.0]
4200 |
➞ |
M_mal__L_m + M_nad_m ➞ M_co2_m + M_nadh_m + M_pyr_m |
|
|
|
|
|
Reaction |
R_HIBDm R_HIBDm
|
3-hydroxyisobutyrate dehydrogenase, mitochondrial
[-1000.0
1000.0]
11112 |
⇆ |
M_3hmp_m + M_nad_m ⇆ M_2mop_m + M_h_m + M_nadh_m |
|
|
|
|
|
Reaction |
R_MDHm R_MDHm
|
Malate dehydrogenase mitochondrial
[-1000.0
1000.0]
4191 |
⇆ |
M_mal__L_m + M_nad_m ⇆ M_h_m + M_nadh_m + M_oaa_m |
|
|
|
|
|
Reaction |
R_2OXOADPTm R_2OXOADPTm
|
2-oxoadipate shuttle (cytosol/mitochondria)
[-1000.0
1000.0]
89874 |
⇆ |
M_2oxoadp_c + M_akg_m ⇆ M_2oxoadp_m + M_akg_c |
|
|
|
|
|
Reaction |
R_MDH R_MDH
|
Malate dehydrogenase
[-1000.0
1000.0]
4190 |
⇆ |
M_mal__L_c + M_nad_c ⇆ M_h_c + M_nadh_c + M_oaa_c |
|
|
|
|
|
Reaction |
R_HGNTOR R_HGNTOR
|
Homogentisateoxygen 1 2 oxidoreductase decyclizing
[0.0
1000.0]
3081 |
➞ |
M_hgentis_c + M_o2_c ➞ M_4mlacac_c + M_h_c |
|
|
|
|
|
Reaction |
R_MCPST R_MCPST
|
3-mercaptopyruvate sulfurtransferase
[0.0
1000.0]
4357 |
➞ |
M_cyan_c + M_mercppyr_c ➞ M_h_c + M_pyr_c + M_tcynt_c |
|
|
|
|
|
Reaction |
R_2OXOADOXm R_2OXOADOXm
|
2-Oxoadipate:lipoamde 2-oxidoreductase(decarboxylating and acceptor-succinylating) (mitochondria)
[0.0
1000.0]
((1738 and 8050) and 1743 and 4967) |
➞ |
M_2oxoadp_m + M_coa_m + M_nad_m ➞ M_co2_m + M_glutcoa_m + M_nadh_m |
|
|
|
|
|
Reaction |
R_MCCCrm R_MCCCrm
|
Methylcrotonoyl-CoA carboxylase, mitochondrial
[-1000.0
1000.0]
(56922 and 64087) |
⇆ |
M_3mb2coa_m + M_atp_m + M_hco3_m ⇆ M_3mgcoa_m + M_adp_m + M_h_m + M_pi_m |
|
|
|
|
|
Reaction |
R_2DR1PP R_2DR1PP
|
2-deoxy-D-ribose 1-phosphate phosphorylase
[0.0
1000.0]
|
➞ |
M_2dr1p_c + M_h2o_c ➞ M_drib_c + M_pi_c |
|
|
|
|
|
Reaction |
R_MALtm R_MALtm
|
Malate transport mitochondrial
[-1000.0
1000.0]
1468 |
⇆ |
M_mal__L_c + M_pi_m ⇆ M_mal__L_m + M_pi_c |
|
|
|
|
|
Reaction |
R_HEX7 R_HEX7
|
Hexokinase (D-fructose:ATP)
[0.0
1000.0]
(3098 or 3099 or 3101) |
➞ |
M_atp_c + M_fru_c ➞ M_adp_c + M_f6p_c + M_h_c |
|
|
|
|
|
Reaction |
R_HEX1 R_HEX1
|
Hexokinase (D-glucose:ATP)
[0.0
1000.0]
(3098 or 3099 or 3101) |
➞ |
M_atp_c + M_glc__D_c ➞ M_adp_c + M_g6p_c + M_h_c |
|
|
|
|
|
Reaction |
R_MALTSULtm R_MALTSULtm
|
Malate:thiosulfate antiport, mitochondrial
[-1000.0
1000.0]
1468 |
⇆ |
M_mal__L_c + M_tsul_m ⇆ M_mal__L_m + M_tsul_c |
|
|
|
|
|
Reaction |
R_2AMADPTm R_2AMADPTm
|
L-2-aminoadipate shuttle (cytosol/mitochondria)
[-1000.0
1000.0]
89874 |
⇆ |
M_L2aadp_c + M_akg_m ⇆ M_L2aadp_m + M_akg_c |
|
|
|
|
|
Reaction |
R_MALSO3tm R_MALSO3tm
|
Malate:sulfite antiport, mitochondrial
[-1000.0
1000.0]
1468 |
⇆ |
M_mal__L_c + M_so3_m ⇆ M_mal__L_m + M_so3_c |
|
|
|
|
|
Reaction |
R_HCO3_NAt R_HCO3_NAt
|
Bicarbonate transport (Na/HCO3 cotransport)
[-1000.0
1000.0]
9497 |
⇆ |
M_hco3_e + M_na1_e ⇆ M_hco3_c + M_na1_c |
|
|
|
|
|
Reaction |
R_HCO3_CLt R_HCO3_CLt
|
Bicarbonate transport (Cl-/HCO3- exchange)
[-1000.0
1000.0]
(6521 or 6522) |
⇆ |
M_cl_c + M_hco3_e ⇆ M_cl_e + M_hco3_c |
|
|
|
|
|
Reaction |
R_10FTHFtl R_10FTHFtl
|
10-Formyltetrahydrofolate lysosomal transport via diffusion
[-1000.0
1000.0]
|
⇆ |
M_10fthf_c ⇆ M_10fthf_l |
|
|
|
|
|
Reaction |
R_HCO3Em R_HCO3Em
|
HCO3 equilibration reaction
[-1000.0
1000.0]
|
⇆ |
M_co2_m + M_h2o_m ⇆ M_h_m + M_hco3_m |
|
|
|
|
|
Reaction |
R_HACD9m R_HACD9m
|
(2S,3S)-3-hydroxy-2-methylbutanoyl-CoA:NAD+ oxidoreductase
[-1000.0
1000.0]
3028 |
⇆ |
M_3hmbcoa_m + M_nad_m ⇆ M_2maacoa_m + M_h_m + M_nadh_m |
|
|
|
|
|
Reaction |
R_HACD1m R_HACD1m
|
3-Hydroxybutanoyl-CoA:NAD+ oxidoreductase, mitochondria
[-1000.0
1000.0]
(3032 and 3033 and 3028 and 3030) |
⇆ |
M_aacoa_m + M_h_m + M_nadh_m ⇆ M_3hbcoa_m + M_nad_m |
|
|
|
|
|
Reaction |
R_MACACI R_MACACI
|
Maleylacetoacetate isomerase
[0.0
1000.0]
2954 |
➞ |
M_4mlacac_c ➞ M_4fumacac_c |
|
|
|
|
|
Reaction |
R_LYStm R_LYStm
|
Lysine mitochondrial transport via ornithine carrier
[-1000.0
1000.0]
10166 |
⇆ |
M_h_m + M_lys__L_c ⇆ M_h_c + M_lys__L_m |
|
|
|
|
|
Reaction |
R_LYSt5r R_LYSt5r
|
LYStiDF
[0.0
1000.0]
6541 |
➞ |
M_lys__L_e ➞ M_lys__L_c |
|
|
|
|
|
Reaction |
R_LYSt4 R_LYSt4
|
L-lysine transport in via sodium symport
[0.0
1000.0]
(6584 or 11254) |
➞ |
M_lys__L_e + M_na1_e ➞ M_lys__L_c + M_na1_c |
|
|
|
|
|
Reaction |
R_LTDCL R_LTDCL
|
L-Tryptophan decarboxy-lyase
[0.0
1000.0]
1644 |
➞ |
M_h_c + M_trp__L_c ➞ M_co2_c + M_trypta_c |
|
|
|
|
|
Reaction |
R_LTD4DP R_LTD4DP
|
Leukotriene D4 dipeptidase
[-1000.0
1000.0]
|
⇆ |
M_h2o_c + M_leuktrD4_c ⇆ M_gly_c + M_leuktrE4_c |
|
|
|
|
|
Reaction |
R_H2Otp R_H2Otp
|
H2O transport peroxisomal
[-1000.0
1000.0]
|
⇆ |
M_h2o_c ⇆ M_h2o_x |
|
|
|
|
|
Reaction |
R_H2Otly R_H2Otly
|
H2O transport, lysosomal
[-1000.0
1000.0]
|
⇆ |
M_h2o_c ⇆ M_h2o_l |
|
|
|
|
|
Reaction |
R_H2O2tm R_H2O2tm
|
Hydrogen peroxide transport via diffusion, mitochondria
[-1000.0
1000.0]
|
⇆ |
M_h2o2_c ⇆ M_h2o2_m |
|
|
|
|
|
Reaction |
R_LTC4Sr R_LTC4Sr
|
Leukotriene C4 synthase
[0.0
1000.0]
(4056 or 4258 or 4259) |
➞ |
M_gthrd_r + M_leuktrA4_r ➞ M_leuktrC4_r |
|
|
|
|
|
Reaction |
R_H2O2t R_H2O2t
|
Hydrogen peroxide transport via diffusion
[-1000.0
1000.0]
|
⇆ |
M_h2o2_e ⇆ M_h2o2_c |
|
|
|
|
|
Reaction |
R_LSOProd R_LSOProd
|
LSOProd
[0.0
1000.0]
|
➞ |
M_focytC_m + M_o2_m ➞ M_ficytC_m + M_o2s_m |
|
|
|
|
|
Reaction |
R_10FTHF7GLUtm R_10FTHF7GLUtm
|
7-glutamyl-10FTHF transport, mitochondrial
[0.0
1000.0]
|
➞ |
M_10fthf7glu_m ➞ M_10fthf7glu_c |
|
|
|
|
|
Reaction |
R_LNLCt R_LNLCt
|
Linoleic acid (n-C18:2) transport in via diffusion
[-1000.0
1000.0]
|
⇆ |
M_lnlc_e ⇆ M_lnlc_c |
|
|
|
|
|
Reaction |
R_LNLCCRNt R_LNLCCRNt
|
Transport into the mitochondria (carnitine)
[0.0
1000.0]
788 |
➞ |
M_lnlccrn_c ➞ M_lnlccrn_m |
|
|
|
|
|
Reaction |
R_LNLCCPT2 R_LNLCCPT2
|
Carnitine transferase
[0.0
1000.0]
1376 |
➞ |
M_coa_m + M_lnlccrn_m ➞ M_crn_m + M_lnlccoa_m |
|
|
|
|
|
Reaction |
R_H2CO3D2 R_H2CO3D2
|
Carboxylic acid dissociation
[-1000.0
1000.0]
|
⇆ |
M_h_c + M_hco3_c ⇆ M_h2co3_c |
|
|
|
|
|
Reaction |
R_H2CO3D R_H2CO3D
|
Carboxylic acid dissociation
[-1000.0
1000.0]
(760 or 377677 or 759) |
⇆ |
M_co2_c + M_h2o_c ⇆ M_h2co3_c |
|
|
|
|
|
Reaction |
R_GULNter R_GULNter
|
L-gulonate endoplasmic reticular export
[0.0
1000.0]
|
➞ |
M_guln__L_r ➞ M_guln__L_c |
|
|
|
|
|
Reaction |
R_GULNDer R_GULNDer
|
Gulonate dehydrogenase, endoplasmic reticulum
[-1000.0
1000.0]
|
⇆ |
M_glcur_r + M_h_r + M_nadph_r ⇆ M_guln__L_r + M_nadp_r |
|
|
|
|
|
Reaction |
R_LNLCCPT1 R_LNLCCPT1
|
Carnitine O-palmitoyltransferase
[0.0
1000.0]
1374 |
➞ |
M_crn_c + M_lnlccoa_c ➞ M_coa_c + M_lnlccrn_c |
|
|
|
|
|
Reaction |
R_GULN3D R_GULN3D
|
L-gulonate 3-dehydrogenase
[-1000.0
1000.0]
|
⇆ |
M_guln__L_c + M_nad_c ⇆ M_3dhguln_c + M_h_c + M_nadh_c |
|
|
|
|
|
Reaction |
R_10FTHF7GLUtl R_10FTHF7GLUtl
|
7-glutamyl-10FTHF transport, lysosomal
[0.0
1000.0]
|
➞ |
M_10fthf7glu_c ➞ M_10fthf7glu_l |
|
|
|
|
|
Reaction |
R_LGTHL R_LGTHL
|
Lactoylglutathione lyase
[0.0
1000.0]
2739 |
➞ |
M_gthrd_c + M_mthgxl_c ➞ M_lgt__S_c |
|
|
|
|
|
Reaction |
R_GUAPRT R_GUAPRT
|
Guanine phosphoribosyltransferase
[0.0
1000.0]
3251 |
➞ |
M_gua_c + M_prpp_c ➞ M_gmp_c + M_ppi_c |
|
|
|
|
|
Reaction |
R_10FTHF6GLUtm R_10FTHF6GLUtm
|
6-glutamyl-10FTHF transport, mitochondrial
[0.0
1000.0]
|
➞ |
M_10fthf6glu_m ➞ M_10fthf6glu_c |
|
|
|
|
|
Reaction |
R_GUACYC R_GUACYC
|
Guanylate cyclase
[0.0
1000.0]
((2977 and 2983) or (2982 and 2974) or (2977 and 2974) or (2982 and 2983) or 2984 or 2986 or 4881 or 4882 or 3000) |
➞ |
M_gtp_c ➞ M_35cgmp_c + M_ppi_c |
|
|
|
|
|
Reaction |
R_LEUt4 R_LEUt4
|
L-leucine transport in via sodium symport
[-1000.0
1000.0]
(6520 or 6541) |
⇆ |
M_leu__L_e + M_na1_e ⇆ M_leu__L_c + M_na1_c |
|
|
|
|
|
Reaction |
R_SK_txb2_c R_SK_txb2_c
|
Sink txb c
[-1000.0
1000.0]
|
⇆ |
M_txb2_c ⇆ |
|
|
|
|
|
Reaction |
R_LEUKTRF4t R_LEUKTRF4t
|
Leukotriene F4 transport
[-1000.0
1000.0]
|
⇆ |
M_leuktrF4_e ⇆ M_leuktrF4_c |
|
|
|
|
|
Reaction |
R_LEUKTRD4tr R_LEUKTRD4tr
|
Leukotriene intracellular transport
[-1000.0
1000.0]
|
⇆ |
M_leuktrD4_c ⇆ M_leuktrD4_r |
|
|
|
|
|
Reaction |
R_EX_gthox_e R_EX_gthox_e
|
Oxidized glutathione exchange
[-1000.0
1000.0]
|
⇆ |
M_gthox_e ⇆ |
|
|
|
|
|
Reaction |
R_EX_glyb_e R_EX_glyb_e
|
Glycine betaine exchange
[-1000.0
1000.0]
|
⇆ |
M_glyb_e ⇆ |
|
|
|
|
|
Reaction |
R_EX_gly_e R_EX_gly_e
|
Glycine exchange
[-1000.0
1000.0]
|
⇆ |
M_gly_e ⇆ |
|
|
|
|
|
Reaction |
R_DM_na1_c R_DM_na1_c
|
Sink na1
[-1000.0
1000.0]
|
⇆ |
M_na1_c ⇆ |
|
|
|
|
|
Reaction |
R_EX_glu__L_e R_EX_glu__L_e
|
L-Glutamate exchange
[-1000.0
1000.0]
|
⇆ |
M_glu__L_e ⇆ |
|
|
|
|
|
Reaction |
R_LEUKTRA4tr R_LEUKTRA4tr
|
Leukotriene intracellular transport
[-1000.0
1000.0]
|
⇆ |
M_leuktrA4_c ⇆ M_leuktrA4_r |
|
|
|
|
|
Reaction |
R_SK_mal__L_c R_SK_mal__L_c
|
Sink mal c
[-1000.0
1000.0]
|
⇆ |
M_mal__L_c ⇆ |
|
|
|
|
|
Reaction |
R_LDH_L R_LDH_L
|
L-lactate dehydrogenase
[-1000.0
1000.0]
((3945 and 3939) or 3939 or 3945 or 3948 or 92483 or 55293 or 160287) |
⇆ |
M_lac__L_c + M_nad_c ⇆ M_h_c + M_nadh_c + M_pyr_c |
|
|
|
|
|
Reaction |
R_LDH_D R_LDH_D
|
D-lactate dehydrogenase
[-1000.0
1000.0]
197257 |
⇆ |
M_lac__D_c + M_nad_c ⇆ M_h_c + M_nadh_c + M_pyr_c |
|
|
|
|
|
Reaction |
R_LCADi_D R_LCADi_D
|
Lactaldehyde dehydrogenase
[0.0
1000.0]
(224 or 216 or 223) |
➞ |
M_h2o_c + M_lald__D_c + M_nad_c ➞ 2.0 M_h_c + M_lac__D_c + M_nadh_c |
|
|
|
|
|
Reaction |
R_LCADi R_LCADi
|
Lactaldehyde dehydrogenase
[0.0
1000.0]
(224 or 216 or 223) |
➞ |
M_h2o_c + M_lald__L_c + M_nad_c ➞ 2.0 M_h_c + M_lac__L_c + M_nadh_c |
|
|
|
|
|
Reaction |
R_EX_gln__L_e R_EX_gln__L_e
|
L-Glutamine exchange
[-1000.0
1000.0]
|
⇆ |
M_gln__L_e ⇆ |
|
|
|
|
|
Reaction |
R_EX_glc__D_e R_EX_glc__D_e
|
D-Glucose exchange
[-1000.0
1000.0]
|
⇆ |
M_glc__D_e ⇆ |
|
|
|
|
|
Reaction |
R_EX_gdp_e R_EX_gdp_e
|
GDP exchange
[-1000.0
1000.0]
|
⇆ |
M_gdp_e ⇆ |
|
|
|
|
|
Reaction |
R_LALDO2x R_LALDO2x
|
D-Lactaldehyde:NAD+ 1-oxidoreductase
[0.0
1000.0]
8574 |
➞ |
M_h_c + M_mthgxl_c + M_nadh_c ➞ M_lald__D_c + M_nad_c |
|
|
|
|
|
Reaction |
R_LALDO2 R_LALDO2
|
D-Lactaldehyde:NADP+ 1-oxidoreductase
[0.0
1000.0]
(10327 or 8574 or 231) |
➞ |
M_h_c + M_mthgxl_c + M_nadph_c ➞ M_lald__D_c + M_nadp_c |
|
|
|
|
|
Reaction |
R_EX_gal_e R_EX_gal_e
|
D-Galactose exchange
[-1000.0
1000.0]
|
⇆ |
M_gal_e ⇆ |
|
|
|
|
|
Reaction |
R_SK_ind3ac_c R_SK_ind3ac_c
|
Sink ind3ac c
[-1000.0
1000.0]
|
⇆ |
M_ind3ac_c ⇆ |
|
|
|
|
|
Reaction |
R_L_LACt2r R_L_LACt2r
|
L lactate reversible transport via proton symport
[-1000.0
1000.0]
(9194 or 9123) |
⇆ |
M_h_e + M_lac__L_e ⇆ M_h_c + M_lac__L_c |
|
|
|
|
|
Reaction |
R_KHK R_KHK
|
Ketohexokinase
[0.0
1000.0]
3795 |
➞ |
M_atp_c + M_fru_c ➞ M_adp_c + M_f1p_c + M_h_c |
|
|
|
|
|
Reaction |
R_EX_fru_e R_EX_fru_e
|
D-Fructose exchange
[-1000.0
1000.0]
|
⇆ |
M_fru_e ⇆ |
|
|
|
|
|
Reaction |
R_SK_homoval_c R_SK_homoval_c
|
Sink homoval c
[-1000.0
1000.0]
|
⇆ |
M_homoval_c ⇆ |
|
|
|
|
|
Reaction |
R_EX_fe2_e R_EX_fe2_e
|
Fe2+ exchange
[-1000.0
1000.0]
|
⇆ |
M_fe2_e ⇆ |
|
|
|
|
|
Reaction |
R_KAS8 R_KAS8
|
B-ketoacyl synthetase (palmitate, n-C16:0)
[0.0
1000.0]
2194 |
➞ |
M_accoa_c + 20.0 M_h_c + 7.0 M_malcoa_c + 14.0 M_nadph_c ➞ 7.0 M_co2_c + 8.0 M_coa_c + 6.0 M_h2o_c + M_hdca_c + 14.0 M_nadp_c |
|
|
|
|
|
Reaction |
R_INSTt4_2 R_INSTt4_2
|
Inositol transport via sodium symport
[-1000.0
1000.0]
115584 |
⇆ |
M_inost_e + 2.0 M_na1_e ⇆ M_inost_c + 2.0 M_na1_c |
|
|
|
|
|
Reaction |
R_SK_ca2_c R_SK_ca2_c
|
Sink ca2 c
[-1000.0
1000.0]
|
⇆ |
M_ca2_c ⇆ |
|
|
|
|
|
Reaction |
R_INSTt4 R_INSTt4
|
Inositol transport via sodium symport
[-1000.0
1000.0]
6526 |
⇆ |
M_inost_e + M_na1_e ⇆ M_inost_c + M_na1_c |
|
|
|
|
|
Reaction |
R_INOSTO R_INOSTO
|
Myo-Inositol:oxygen oxidoreductase
[0.0
1000.0]
55586 |
➞ |
M_inost_c + M_o2_c ➞ M_glcur_c + M_h2o_c + M_h_c |
|
|
|
|
|
Reaction |
R_EX_dopasf_e R_EX_dopasf_e
|
Dopamine 3-O-sulfate exchange
[-1000.0
1000.0]
|
⇆ |
M_dopasf_e ⇆ |
|
|
|
|
|
Reaction |
R_SK_5moxact_c R_SK_5moxact_c
|
Sink 5moxact c
[-1000.0
1000.0]
|
⇆ |
M_5moxact_c ⇆ |
|
|
|
|
|
Reaction |
R_EX_dopa_e R_EX_dopa_e
|
Dopamine exchange
[-1000.0
1000.0]
|
⇆ |
M_dopa_e ⇆ |
|
|
|
|
|
Reaction |
R_EX_dhdascb_e R_EX_dhdascb_e
|
Dehydroascorbate exchange
[-1000.0
1000.0]
|
⇆ |
M_dhdascb_e ⇆ |
|
|
|
|
|
Reaction |
R_IMPD R_IMPD
|
IMP dehydrogenase
[0.0
1000.0]
(3614 or 3615) |
➞ |
M_h2o_c + M_imp_c + M_nad_c ➞ M_h_c + M_nadh_c + M_xmp_c |
|
|
|
|
|
Reaction |
R_IMPC R_IMPC
|
IMP cyclohydrolase
[-1000.0
1000.0]
471 |
⇆ |
M_h2o_c + M_imp_c ⇆ M_fprica_c |
|
|
|
|
|
Reaction |
R_EX_cytd_e R_EX_cytd_e
|
Cytidine exchange
[-1000.0
1000.0]
|
⇆ |
M_cytd_e ⇆ |
|
|
|
|
|
Reaction |
R_ILEtec R_ILEtec
|
L-isoleucine transport via diffusion (extracellular to cytosol)
[-1000.0
1000.0]
(8501 or 124935) |
⇆ |
M_ile__L_e ⇆ M_ile__L_c |
|
|
|
|
|
Reaction |
R_SK_4mop_c R_SK_4mop_c
|
Sink 4mop
[-1000.0
1000.0]
|
⇆ |
M_4mop_c ⇆ |
|
|
|
|
|
Reaction |
R_ILEt4 R_ILEt4
|
L-isoleucine transport in via sodium symport
[-1000.0
1000.0]
11254 |
⇆ |
M_ile__L_e + M_na1_e ⇆ M_ile__L_c + M_na1_c |
|
|
|
|
|
Reaction |
R_EX_cys__L_e R_EX_cys__L_e
|
L-Cysteine exchange
[-1000.0
1000.0]
|
⇆ |
M_cys__L_e ⇆ |
|
|
|
|
|
Reaction |
R_EX_cyan_e R_EX_cyan_e
|
Hydrogen cyanide exchange
[-1000.0
1000.0]
|
⇆ |
M_cyan_e ⇆ |
|
|
|
|
|
Reaction |
R_ILETA R_ILETA
|
Isoleucine transaminase
[-1000.0
1000.0]
586 |
⇆ |
M_akg_c + M_ile__L_c ⇆ M_3mop_c + M_glu__L_c |
|
|
|
|
|
Reaction |
R_SK_15HPET_c R_SK_15HPET_c
|
Sink 15HPET c
[-1000.0
1000.0]
|
⇆ |
M_15HPET_c ⇆ |
|
|
|
|
|
Reaction |
R_ICDHym R_ICDHym
|
Isocitrate dehydrogenase NADP
[-1000.0
1000.0]
3418 |
⇆ |
M_icit_m + M_nadp_m ⇆ M_akg_m + M_co2_m + M_nadph_m |
|
|
|
|
|
Reaction |
R_EX_creat_e R_EX_creat_e
|
Creatine exchange
[-1000.0
1000.0]
|
⇆ |
M_creat_e ⇆ |
|
|
|
|
|
Reaction |
R_SK_12harachd_c R_SK_12harachd_c
|
Sink 12harachd c
[-1000.0
1000.0]
|
⇆ |
M_12harachd_c ⇆ |
|
|
|
|
|
Reaction |
R_EX_co2_e R_EX_co2_e
|
CO2 exchange
[-1000.0
1000.0]
|
⇆ |
M_co2_e ⇆ |
|
|
|
|
|
Reaction |
R_EX_co_e R_EX_co_e
|
EX co LPAREN e RPAREN
[-1000.0
1000.0]
|
⇆ |
M_co_e ⇆ |
|
|
|
|
|
Reaction |
R_EX_cit_e R_EX_cit_e
|
Citrate exchange
[-1000.0
1000.0]
|
⇆ |
M_cit_e ⇆ |
|
|
|
|
|
Reaction |
R_EX_chol_e R_EX_chol_e
|
Choline exchange
[-1000.0
1000.0]
|
⇆ |
M_chol_e ⇆ |
|
|
|
|
|
Reaction |
R_ICDHyr R_ICDHyr
|
Isocitrate dehydrogenase (NADP)
[0.0
1000.0]
3417 |
➞ |
M_icit_c + M_nadp_c ➞ M_akg_c + M_co2_c + M_nadph_c |
|
|
|
|
|
Reaction |
R_ICDHxm R_ICDHxm
|
Isocitrate dehydrogenase NAD
[-1000.0
1000.0]
(3419 and 3420 and 3421) |
⇆ |
M_icit_m + M_nad_m ⇆ M_akg_m + M_co2_m + M_nadh_m |
|
|
|
|
|
Reaction |
R_Htx R_Htx
|
H transporter, peroxisome
[-1000.0
1000.0]
|
⇆ |
M_h_c ⇆ M_h_x |
|
|
|
|
|
Reaction |
R_Htr R_Htr
|
H transporter, endoplasmic reticulum
[-1000.0
1000.0]
|
⇆ |
M_h_c ⇆ M_h_r |
|
|
|
|
|
Reaction |
R_HYXNt R_HYXNt
|
Hypoxanthine transport
[-1000.0
1000.0]
3177 |
⇆ |
M_hxan_e ⇆ M_hxan_c |
|
|
|
|
|
Reaction |
R_HXPRT R_HXPRT
|
Hypoxanthine phosphoribosyltransferase (Hypoxanthine)
[0.0
1000.0]
3251 |
➞ |
M_hxan_c + M_prpp_c ➞ M_imp_c + M_ppi_c |
|
|
|
|
|
Reaction |
R_HPETOX R_HPETOX
|
HPETOX
[-1000.0
1000.0]
|
⇆ |
M_12HPET_c + 2.0 M_gthrd_c ⇆ M_12harachd_c + M_gthox_c + M_h2o_c |
|
|
|
|
|
Reaction |
R_HPACtr R_HPACtr
|
Hydroxyphenylacetate transport via diffusion
[-1000.0
1000.0]
|
⇆ |
M_4hphac_c ⇆ M_4hphac_e |
|
|
|
|
|
Reaction |
R_EX_ca2_e R_EX_ca2_e
|
Calcium exchange
[-1000.0
1000.0]
|
⇆ |
M_ca2_e ⇆ |
|
|
|
|
|
Reaction |
R_EX_bilirub_e R_EX_bilirub_e
|
Bilirubin exchange
[-1000.0
1000.0]
|
⇆ |
M_bilirub_e ⇆ |
|
|
|
|
|
Reaction |
R_EX_asp__L_e R_EX_asp__L_e
|
L-Aspartate exchange
[-1000.0
1000.0]
|
⇆ |
M_asp__L_e ⇆ |
|
|
|
|
|
Reaction |
R_EX_asn__L_e R_EX_asn__L_e
|
L-Asparagine exchange
[-1000.0
1000.0]
|
⇆ |
M_asn__L_e ⇆ |
|
|
|
|
|
Reaction |
R_EX_val__L_e R_EX_val__L_e
|
L-Valine exchange
[-1000.0
1000.0]
|
⇆ |
M_val__L_e ⇆ |
|
|
|
|
|
Reaction |
R_EX_ascb__L_e R_EX_ascb__L_e
|
L-Ascorbate exchange
[-1000.0
1000.0]
|
⇆ |
M_ascb__L_e ⇆ |
|
|
|
|
|
Reaction |
R_EX_arg__L_e R_EX_arg__L_e
|
L-Arginine exchange
[-1000.0
1000.0]
|
⇆ |
M_arg__L_e ⇆ |
|
|
|
|
|
Reaction |
R_EX_arachd_e R_EX_arachd_e
|
NC20:4 exchange
[-1000.0
1000.0]
|
⇆ |
M_arachd_e ⇆ |
|
|
|
|
|
Reaction |
R_EX_amp_e R_EX_amp_e
|
AMP exchange
[-1000.0
1000.0]
|
⇆ |
M_amp_e ⇆ |
|
|
|
|
|
Reaction |
R_EX_ala__L_e R_EX_ala__L_e
|
L-Alanine exchange
[-1000.0
1000.0]
|
⇆ |
M_ala__L_e ⇆ |
|
|
|
|
|
Reaction |
R_EX_adrnl_e R_EX_adrnl_e
|
Adrenaline exchange
[-1000.0
1000.0]
|
⇆ |
M_adrnl_e ⇆ |
|
|
|
|
|
Reaction |
R_EX_adprib_e R_EX_adprib_e
|
ADPribose exchange
[-1000.0
1000.0]
|
⇆ |
M_adprib_e ⇆ |
|
|
|
|
|
Reaction |
R_EX_adp_e R_EX_adp_e
|
Adp exchange
[-1000.0
1000.0]
|
⇆ |
M_adp_e ⇆ |
|
|
|
|
|
Reaction |
R_EX_adn_e R_EX_adn_e
|
Adenosine exchange
[-1000.0
1000.0]
|
⇆ |
M_adn_e ⇆ |
|
|
|
|
|
Reaction |
R_EX_ade_e R_EX_ade_e
|
Adenine exchange
[-1000.0
1000.0]
|
⇆ |
M_ade_e ⇆ |
|
|
|
|
|
Reaction |
R_EX_ac_e R_EX_ac_e
|
Acetate exchange
[-1000.0
1000.0]
|
⇆ |
M_ac_e ⇆ |
|
|
|
|
|
Reaction |
R_EX_cysi__L_e R_EX_cysi__L_e
|
L Cystine exchange
[-1000.0
1000.0]
|
⇆ |
M_cysi__L_e ⇆ |
|
|
|
|
|
Reaction |
R_EX_4nphsf_e R_EX_4nphsf_e
|
4-Nitrophenyl sulfate exchange
[-1000.0
1000.0]
|
⇆ |
M_4nphsf_e ⇆ |
|
|
|
|
|
Reaction |
R_EX_4nph_e R_EX_4nph_e
|
4-Nitrophenol exchange
[-1000.0
1000.0]
|
⇆ |
M_4nph_e ⇆ |
|
|
|
|
|
Reaction |
R_EX_4hphac_e R_EX_4hphac_e
|
4 hydroxyphenylacetate exchange
[-1000.0
1000.0]
|
⇆ |
M_4hphac_e ⇆ |
|
|
|
|
|
Reaction |
R_EX_35cgmp_e R_EX_35cgmp_e
|
3',5'-Cyclic GMP exchange
[-1000.0
1000.0]
|
⇆ |
M_35cgmp_e ⇆ |
|
|
|
|
|
Reaction |
R_SK_xan_c R_SK_xan_c
|
Sink xan c
[-1000.0
1000.0]
|
⇆ |
M_xan_c ⇆ |
|
|
|
|
|
Reaction |
R_EX_uri_e R_EX_uri_e
|
Uridine exchange
[-1000.0
1000.0]
|
⇆ |
M_uri_e ⇆ |
|
|
|
|
|
Reaction |
R_EX_urea_e R_EX_urea_e
|
Urea exchange
[-1000.0
1000.0]
|
⇆ |
M_urea_e ⇆ |
|
|
|
|
|
Reaction |
R_EX_urate_e R_EX_urate_e
|
Urate exchange
[-1000.0
1000.0]
|
⇆ |
M_urate_e ⇆ |
|
|
|
|
|
Reaction |
R_EX_ura_e R_EX_ura_e
|
Uracil exchange
[-1000.0
1000.0]
|
⇆ |
M_ura_e ⇆ |
|
|
|
|
|
Reaction |
R_EX_tyr__L_e R_EX_tyr__L_e
|
L-Tyrosine exchange
[-1000.0
1000.0]
|
⇆ |
M_tyr__L_e ⇆ |
|
|
|
|
|
Reaction |
R_EX_tymsf_e R_EX_tymsf_e
|
Tyramine O-sulfate exchange
[-1000.0
1000.0]
|
⇆ |
M_tymsf_e ⇆ |
|
|
|
|
|
Reaction |
R_EX_txa2_e R_EX_txa2_e
|
Thromboxane A2 exchange
[-1000.0
1000.0]
|
⇆ |
M_txa2_e ⇆ |
|
|
|
|
|
Reaction |
R_EX_tsul_e R_EX_tsul_e
|
Thiosulfate exchange
[-1000.0
1000.0]
|
⇆ |
M_tsul_e ⇆ |
|
|
|
|
|
Reaction |
R_EX_trp__L_e R_EX_trp__L_e
|
L-Tryptophan exchange
[-1000.0
1000.0]
|
⇆ |
M_trp__L_e ⇆ |
|
|
|
|
|
Reaction |
R_EX_thymd_e R_EX_thymd_e
|
Thymidine exchange
[-1000.0
1000.0]
|
⇆ |
M_thymd_e ⇆ |
|
|
|
|
|
Reaction |
R_EX_thym_e R_EX_thym_e
|
Thymine exchange
[-1000.0
1000.0]
|
⇆ |
M_thym_e ⇆ |
|
|
|
|
|
Reaction |
R_EX_tcynt_e R_EX_tcynt_e
|
Thiocyanate exchange
[-1000.0
1000.0]
|
⇆ |
M_tcynt_e ⇆ |
|
|
|
|
|
Reaction |
R_EX_succ_e R_EX_succ_e
|
Succinate exchange
[-1000.0
1000.0]
|
⇆ |
M_succ_e ⇆ |
|
|
|
|
|
Reaction |
R_EX_srtn_e R_EX_srtn_e
|
Serotonin exchange
[-1000.0
1000.0]
|
⇆ |
M_srtn_e ⇆ |
|
|
|
|
|
Reaction |
R_EX_sphs1p_e R_EX_sphs1p_e
|
Sphingosine 1-phosphate exchange
[-1000.0
1000.0]
|
⇆ |
M_sphs1p_e ⇆ |
|
|
|
|
|
Reaction |
R_EX_spc_hs_e R_EX_spc_hs_e
|
Sphingosylphosphorylcholine (homo sapiens) exchange
[-1000.0
1000.0]
|
⇆ |
M_spc_hs_e ⇆ |
|
|
|
|
|
Reaction |
R_EX_so4_e R_EX_so4_e
|
Sulfate exchange
[-1000.0
1000.0]
|
⇆ |
M_so4_e ⇆ |
|
|
|
|
|
Reaction |
R_EX_ser__L_e R_EX_ser__L_e
|
L-Serine exchange
[-1000.0
1000.0]
|
⇆ |
M_ser__L_e ⇆ |
|
|
|
|
|
Reaction |
R_EX_pyr_e R_EX_pyr_e
|
Pyruvate exchange
[-1000.0
1000.0]
|
⇆ |
M_pyr_e ⇆ |
|
|
|
|
|
Reaction |
R_EX_prostgd2_e R_EX_prostgd2_e
|
Prostaglandin D2 exchange
[-1000.0
1000.0]
|
⇆ |
M_prostgd2_e ⇆ |
|
|
|
|
|
Reaction |
R_EX_pro__L_e R_EX_pro__L_e
|
L-Proline exchange
[-1000.0
1000.0]
|
⇆ |
M_pro__L_e ⇆ |
|
|
|
|
|
Reaction |
R_EX_pi_e R_EX_pi_e
|
Phosphate exchange
[-1000.0
1000.0]
|
⇆ |
M_pi_e ⇆ |
|
|
|
|
|
Reaction |
R_EX_pheme_e R_EX_pheme_e
|
Protoheme exchange
[-1000.0
1000.0]
|
⇆ |
M_pheme_e ⇆ |
|
|
|
|
|
Reaction |
R_EX_pheacgln_e R_EX_pheacgln_e
|
Alpha-N-Phenylacetyl-L-glutamine exchange
[-1000.0
1000.0]
|
⇆ |
M_pheacgln_e ⇆ |
|
|
|
|
|
Reaction |
R_EX_phe__L_e R_EX_phe__L_e
|
L-Phenylalanine exchange
[-1000.0
1000.0]
|
⇆ |
M_phe__L_e ⇆ |
|
|
|
|
|
Reaction |
R_EX_orn_e R_EX_orn_e
|
Ornithine exchange
[-1000.0
1000.0]
|
⇆ |
M_orn_e ⇆ |
|
|
|
|
|
Reaction |
R_EX_ocdcea_e R_EX_ocdcea_e
|
Octadecenoate (n-C18:1) exchange
[-1000.0
1000.0]
|
⇆ |
M_ocdcea_e ⇆ |
|
|
|
|
|
Reaction |
R_EX_ocdca_e R_EX_ocdca_e
|
Octadecanoate (n-C18:0) exchange
[-1000.0
1000.0]
|
⇆ |
M_ocdca_e ⇆ |
|
|
|
|
|
Reaction |
R_EX_o2s_e R_EX_o2s_e
|
Superoxide anion exchange
[-1000.0
1000.0]
|
⇆ |
M_o2s_e ⇆ |
|
|
|
|
|
Reaction |
R_EX_o2_e R_EX_o2_e
|
O2 exchange
[-1000.0
1000.0]
|
⇆ |
M_o2_e ⇆ |
|
|
|
|
|
Reaction |
R_EX_nrpphrsf_e R_EX_nrpphrsf_e
|
Sulfate derivative of norepinephrine exchange
[-1000.0
1000.0]
|
⇆ |
M_nrpphrsf_e ⇆ |
|
|
|
|
|
Reaction |
R_EX_no_e R_EX_no_e
|
Nitric oxide exchange
[-1000.0
1000.0]
|
⇆ |
M_no_e ⇆ |
|
|
|
|
|
Reaction |
R_EX_nh4_e R_EX_nh4_e
|
Ammonia exchange
[-1000.0
1000.0]
|
⇆ |
M_nh4_e ⇆ |
|
|
|
|
|
Reaction |
R_EX_ncam_e R_EX_ncam_e
|
Nicotinamide exchange
[-1000.0
1000.0]
|
⇆ |
M_ncam_e ⇆ |
|
|
|
|
|
Reaction |
R_EX_nad_e R_EX_nad_e
|
Nicotinamide adenine dinucleotide exchange
[-1000.0
1000.0]
|
⇆ |
M_nad_e ⇆ |
|
|
|
|
|
Reaction |
R_EX_na1_e R_EX_na1_e
|
Sodium exchange
[-1000.0
1000.0]
|
⇆ |
M_na1_e ⇆ |
|
|
|
|
|
Reaction |
R_EX_met__L_e R_EX_met__L_e
|
L-Methionine exchange
[-1000.0
1000.0]
|
⇆ |
M_met__L_e ⇆ |
|
|
|
|
|
Reaction |
R_EX_lys__L_e R_EX_lys__L_e
|
L-Lysine exchange
[-1000.0
1000.0]
|
⇆ |
M_lys__L_e ⇆ |
|
|
|
|
|
Reaction |
R_EX_lnlc_e R_EX_lnlc_e
|
Linoleic acid (all cis C18:2) exchange
[-1000.0
1000.0]
|
⇆ |
M_lnlc_e ⇆ |
|
|
|
|
|
Reaction |
R_EX_leuktrF4_e R_EX_leuktrF4_e
|
Leukotriene F4 exchange
[-1000.0
1000.0]
|
⇆ |
M_leuktrF4_e ⇆ |
|
|
|
|
|
Reaction |
R_EX_lac__L_e R_EX_lac__L_e
|
L-Lactate exchange
[-1000.0
1000.0]
|
⇆ |
M_lac__L_e ⇆ |
|
|
|
|
|