Sahar Golabi
Maryam Adelipour
Sara Mobarak
Maghsud Piri
Maryam Seyedtabib
Reza Bagheri
Katsuhiko Suzuki
Damoon Ashtari Larki
Fatemeh Maghsoudi
Mahshid Naghashpour
2021-08-26
<p><em>Background: </em>Vitamin D and zinc are important components of nutritional immunity. This study compared the serum concentrations of vitamin D and zinc in COVID-19 outpatients with those of non-infected participants. Clinical symptoms and associations with vitamin D and zinc status were also examined. <em>Methods: </em>A checklist and laboratory examination were applied to collect data in a health service center-based descriptive-analytical cross-sectional study conducted on 53 infected outpatients with COVID-19 and 53 non-infected participants of both sexes. <em>Results: </em>Lower serum concentration of total 25-hydroxyvitamin D [25(OH)D] were observed in patients with moderate illness (18.9±11.5 ng/mL) than in patients with asymptomatic or mild illness (29.2±18.3 ng/mL) (p=0.054). Also, infected patients (100.6±17.8 µg/dL) showed lower serum concentration of zinc than non-infected participants (113.8±13.4 µg/dL) (p=0.013). Patients with normal and insufficient vitamin D status at the time of admission had decreased odds ratios of general symptoms of COVID-19 (odds ratio, 0.19; p≤0.001 for normal and odds ratio, 0.3; p=0.007 for insufficient vitamin D status) compared to patients with vitamin D deficiency. <em>Conclusion: </em>This study revealed the importance of 25(OH)D measurement as a relatively easy option to predict the progression of general and pulmonary symptoms. Also, this study showed that a poor zinc status of the outpatients might affect the disease onset of COVID-19.</p>
https://doi.org/10.5281/zenodo.5266352
oai:zenodo.org:5266352
Zenodo
https://zenodo.org/communities/covid-19
https://doi.org/10.5281/zenodo.5266351
info:eu-repo/semantics/openAccess
Creative Commons Attribution 4.0 International
https://creativecommons.org/licenses/by/4.0/legalcode
Clinical symptoms
Vitamin D status
Zinc status
Sunlight exposure
COVID-19
The Association between Vitamin D and Zinc Status with the Disease Onset and Progression of Clinical Symptoms among Outpatients Infected with COVID-19 and Non-Infected Participants: A Cross-Sectional Study
info:eu-repo/semantics/article