Journal article Open Access

The Association between Vitamin D and Zinc Status with the Disease Onset and Progression of Clinical Symptoms among Outpatients Infected with COVID-19 and Non-Infected Participants: A Cross-Sectional Study

Sahar Golabi; Maryam Adelipour; Sara Mobarak; Maghsud Piri; Maryam Seyedtabib; Reza Bagheri; Katsuhiko Suzuki; Damoon Ashtari Larki; Fatemeh Maghsoudi; Mahshid Naghashpour


DataCite XML Export

<?xml version='1.0' encoding='utf-8'?>
<resource xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns="http://datacite.org/schema/kernel-4" xsi:schemaLocation="http://datacite.org/schema/kernel-4 http://schema.datacite.org/meta/kernel-4.1/metadata.xsd">
  <identifier identifierType="DOI">10.5281/zenodo.5266352</identifier>
  <creators>
    <creator>
      <creatorName>Sahar Golabi</creatorName>
      <affiliation>Abadan University of Medical Sciences, Abadan, Iran</affiliation>
    </creator>
    <creator>
      <creatorName>Maryam Adelipour</creatorName>
      <affiliation>Department of Biochemistry, School of Medical Sciences, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran</affiliation>
    </creator>
    <creator>
      <creatorName>Sara Mobarak</creatorName>
      <affiliation>Abadan University of Medical Sciences, Abadan, Iran</affiliation>
    </creator>
    <creator>
      <creatorName>Maghsud Piri</creatorName>
      <affiliation>Abadan University of Medical Sciences, Abadan, Iran</affiliation>
    </creator>
    <creator>
      <creatorName>Maryam Seyedtabib</creatorName>
      <affiliation>Department of Biostatistics and Epidemiology, School of Public Health, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran</affiliation>
    </creator>
    <creator>
      <creatorName>Reza Bagheri</creatorName>
      <affiliation>Department of Exercise Physiology, University of Isfahan, Isfahan, Iran</affiliation>
    </creator>
    <creator>
      <creatorName>Katsuhiko Suzuki</creatorName>
      <affiliation>Faculty of Sport Sciences, Waseda University, 2-579-15 Mikajima, Tokorozawa, 359-1192, Japan</affiliation>
    </creator>
    <creator>
      <creatorName>Damoon Ashtari Larki</creatorName>
      <affiliation>Nutrition and Metabolic Diseases Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran</affiliation>
    </creator>
    <creator>
      <creatorName>Fatemeh Maghsoudi</creatorName>
      <affiliation>Abadan University of Medical Sciences, Abadan, Iran</affiliation>
    </creator>
    <creator>
      <creatorName>Mahshid Naghashpour</creatorName>
      <affiliation>Abadan University of Medical Sciences, Abadan,</affiliation>
    </creator>
  </creators>
  <titles>
    <title>The Association between Vitamin D and Zinc Status with the Disease Onset and Progression of Clinical Symptoms among Outpatients Infected with COVID-19 and Non-Infected Participants: A Cross-Sectional Study</title>
  </titles>
  <publisher>Zenodo</publisher>
  <publicationYear>2021</publicationYear>
  <subjects>
    <subject>Clinical symptoms</subject>
    <subject>Vitamin D status</subject>
    <subject>Zinc status</subject>
    <subject>Sunlight exposure</subject>
    <subject>COVID-19</subject>
  </subjects>
  <dates>
    <date dateType="Issued">2021-08-26</date>
  </dates>
  <resourceType resourceTypeGeneral="JournalArticle"/>
  <alternateIdentifiers>
    <alternateIdentifier alternateIdentifierType="url">https://zenodo.org/record/5266352</alternateIdentifier>
  </alternateIdentifiers>
  <relatedIdentifiers>
    <relatedIdentifier relatedIdentifierType="DOI" relationType="IsVersionOf">10.5281/zenodo.5266351</relatedIdentifier>
    <relatedIdentifier relatedIdentifierType="URL" relationType="IsPartOf">https://zenodo.org/communities/covid-19</relatedIdentifier>
  </relatedIdentifiers>
  <rightsList>
    <rights rightsURI="https://creativecommons.org/licenses/by/4.0/legalcode">Creative Commons Attribution 4.0 International</rights>
    <rights rightsURI="info:eu-repo/semantics/openAccess">Open Access</rights>
  </rightsList>
  <descriptions>
    <description descriptionType="Abstract">&lt;p&gt;&lt;em&gt;Background: &lt;/em&gt;Vitamin D and zinc are important components of nutritional immunity. This study compared the serum concentrations of vitamin D and zinc in COVID-19 outpatients with those of non-infected participants. Clinical symptoms and associations with vitamin D and zinc status were also examined. &lt;em&gt;Methods: &lt;/em&gt;A checklist and laboratory examination were applied to collect data in a health service center-based descriptive-analytical cross-sectional study conducted on 53 infected outpatients with COVID-19 and 53 non-infected participants of both sexes. &lt;em&gt;Results: &lt;/em&gt;Lower serum concentration of total 25-hydroxyvitamin D [25(OH)D] were observed in patients with moderate illness (18.9&amp;plusmn;11.5 ng/mL) than in patients with asymptomatic or mild illness (29.2&amp;plusmn;18.3 ng/mL) (p=0.054). Also, infected patients (100.6&amp;plusmn;17.8 &amp;micro;g/dL) showed lower serum concentration of zinc than non-infected participants (113.8&amp;plusmn;13.4 &amp;micro;g/dL) (p=0.013). Patients with normal and insufficient vitamin D status at the time of admission had decreased odds ratios of general symptoms of COVID-19 (odds ratio, 0.19; p&amp;le;0.001 for normal and odds ratio, 0.3; p=0.007 for insufficient vitamin D status) compared to patients with vitamin D deficiency. &lt;em&gt;Conclusion: &lt;/em&gt;This study revealed the importance of 25(OH)D measurement as a relatively easy option to predict the progression of general and pulmonary symptoms. Also, this study showed that a poor zinc status of the outpatients might affect the disease onset of COVID-19.&lt;/p&gt;</description>
  </descriptions>
</resource>
456
46
views
downloads
All versions This version
Views 456456
Downloads 4646
Data volume 2.5 GB2.5 GB
Unique views 417417
Unique downloads 3838

Share

Cite as