Clipper: p-value-free FDR control on high-throughput data from two conditions

This repository contains the codes and datasets used in the paper 'Clipper: p-value-free FDR control on high-throughput data from two conditions'. The preprint can be found at https://www.biorxiv.org/content/10.1101/2020.11.19.390773v3

1. codes_figures: codes for reproducing all the figures in the paper

2. codes_omics_data: codes used in all omics data analysis, including data preprocessing, synthetic data generation, and application of Clipper.

3. codes_simulation_data_generation: codes for simulation analysis, including generation of simulation datasets and calculation of power and FDR.

4. data_DEG_analysis: the processed human monocyte dataset

5. data_HIC_differentialanalysis: the processed HIC data for GM12878 cell line

6. data_simulation: all the simulation results