July 7, 2021 Preprint Open Access

Holmes, Edward C; Goldstein, Stephen A; Rasmussen, Angela L; Robertson, David L; Crits-Christoph, Alexander; Wertheim, Joel O; Anthony, Simon J; Barclay, Wendy S; Boni, Maciej F; Doherty, Peter C; Farrar, Jeremy; Geoghegan, Jemma L; Jiang, Xiaowei; Leibowitz, Julian L; Neil, Stuart J D; Skern, Tim; Weiss, Susan R; Worobey, Michael; Andersen, Kristian G; Garry, Robert F; Rambaut, Andrew

DataCite XML Export

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  <identifier identifierType="DOI">10.5281/zenodo.5075888</identifier>
  <creators>
    <creator>
      <creatorName>Holmes, Edward C</creatorName>
      <givenName>Edward C</givenName>
      <familyName>Holmes</familyName>
      <affiliation>School of Life and Environmental Sciences and School of Medical Sciences, The University of Sydney, Sydney, NSW 2006, Australia</affiliation>
    </creator>
    <creator>
      <creatorName>Goldstein, Stephen A</creatorName>
      <givenName>Stephen A</givenName>
      <familyName>Goldstein</familyName>
      <affiliation>Department of Human Genetics, University of Utah, Salt Lake City, UT 84112, USA</affiliation>
    </creator>
    <creator>
      <creatorName>Rasmussen, Angela L</creatorName>
      <givenName>Angela L</givenName>
      <familyName>Rasmussen</familyName>
      <affiliation>Vaccine and Infectious Disease Organization, University of Saskatchewan, Saskatoon, SK, S7N 5E3, Canada</affiliation>
    </creator>
    <creator>
      <creatorName>Robertson, David L</creatorName>
      <givenName>David L</givenName>
      <familyName>Robertson</familyName>
      <affiliation>MRC-University of Glasgow Centre for Virus Research, Glasgow, G61 1QH, UK</affiliation>
    </creator>
    <creator>
      <creatorName>Crits-Christoph, Alexander</creatorName>
      <givenName>Alexander</givenName>
      <familyName>Crits-Christoph</familyName>
      <affiliation>Department of Plant and Microbial Biology, University of California Berkeley, Berkeley, CA 94704, USA</affiliation>
    </creator>
    <creator>
      <creatorName>Wertheim, Joel O</creatorName>
      <givenName>Joel O</givenName>
      <familyName>Wertheim</familyName>
      <affiliation>Department of Medicine, University of California San Diego, La Jolla, CA 92093, USA</affiliation>
    </creator>
    <creator>
      <creatorName>Anthony, Simon J</creatorName>
      <givenName>Simon J</givenName>
      <familyName>Anthony</familyName>
      <affiliation>Department of Pathology, Microbiology, and Immunology, University of California Davis School of Veterinary Medicine, Davis, CA 95616, USA</affiliation>
    </creator>
    <creator>
      <creatorName>Barclay, Wendy S</creatorName>
      <givenName>Wendy S</givenName>
      <familyName>Barclay</familyName>
      <affiliation>Department of Infectious Disease, Imperial College London, W2 1PG, UK</affiliation>
    </creator>
    <creator>
      <creatorName>Boni, Maciej F</creatorName>
      <givenName>Maciej F</givenName>
      <familyName>Boni</familyName>
      <affiliation>Center for Infectious Disease Dynamics, Department of Biology, The Pennsylvania State University, University Park, PA 16802, USA</affiliation>
    </creator>
    <creator>
      <creatorName>Doherty, Peter C</creatorName>
      <givenName>Peter C</givenName>
      <familyName>Doherty</familyName>
      <affiliation>Department of Microbiology and Immunology, The University of Melbourne at the Doherty Institute, 792 Elizabeth St, Melbourne, VIC 3000, Australia</affiliation>
    </creator>
    <creator>
      <creatorName>Farrar, Jeremy</creatorName>
      <givenName>Jeremy</givenName>
      <familyName>Farrar</familyName>
      <affiliation>The Wellcome Trust, London, NW1 2BE, UK</affiliation>
    </creator>
    <creator>
      <creatorName>Geoghegan, Jemma L</creatorName>
      <givenName>Jemma L</givenName>
      <familyName>Geoghegan</familyName>
      <affiliation>Department of Microbiology and Immunology, University of Otago, Dunedin, New Zealand. Institute of Environmental Science and Research, Wellington, New Zealand</affiliation>
    </creator>
    <creator>
      <creatorName>Jiang, Xiaowei</creatorName>
      <givenName>Xiaowei</givenName>
      <familyName>Jiang</familyName>
      <affiliation>Department of Biological Sciences, Xi'an Jiaotong-Liverpool University (XJTLU), Suzhou, China</affiliation>
    </creator>
    <creator>
      <creatorName>Leibowitz, Julian L</creatorName>
      <givenName>Julian L</givenName>
      <familyName>Leibowitz</familyName>
      <affiliation>Department of Microbial Pathogenesis and Immunology, Texas A&amp;M University, College Station, TX 77807, USA</affiliation>
    </creator>
    <creator>
      <creatorName>Neil, Stuart J D</creatorName>
      <givenName>Stuart J D</givenName>
      <familyName>Neil</familyName>
      <affiliation>Department of Infectious Diseases, King's College London, Guy's Hospital, London SE1 9RT, UK</affiliation>
    </creator>
    <creator>
      <creatorName>Skern, Tim</creatorName>
      <givenName>Tim</givenName>
      <familyName>Skern</familyName>
      <affiliation>Max Perutz Labs, Medical University of Vienna, Vienna Biocenter, Dr. Bohr-Gasse 9/3, A-1030 Vienna, Austria</affiliation>
    </creator>
    <creator>
      <creatorName>Weiss, Susan R</creatorName>
      <givenName>Susan R</givenName>
      <familyName>Weiss</familyName>
      <affiliation>Perelman School of Medicine, University of Pennsylvania. Philadelphia, PA 19104, USA</affiliation>
    </creator>
    <creator>
      <creatorName>Worobey, Michael</creatorName>
      <givenName>Michael</givenName>
      <familyName>Worobey</familyName>
      <affiliation>Department of Ecology and Evolutionary Biology, University of Arizona, Tucson, AZ 85721, USA</affiliation>
    </creator>
    <creator>
      <creatorName>Andersen, Kristian G</creatorName>
      <givenName>Kristian G</givenName>
      <familyName>Andersen</familyName>
      <affiliation>Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA</affiliation>
    </creator>
    <creator>
      <creatorName>Garry, Robert F</creatorName>
      <givenName>Robert F</givenName>
      <familyName>Garry</familyName>
      <affiliation>Department of Microbiology and Immunology, Tulane University School of Medicine, New Orleans, LA 70112, USA</affiliation>
    </creator>
    <creator>
      <creatorName>Rambaut, Andrew</creatorName>
      <givenName>Andrew</givenName>
      <familyName>Rambaut</familyName>
      <affiliation>Institute of Evolutionary Biology, University of Edinburgh, Edinburgh, EH9 FL, UK</affiliation>
    </creator>
  </creators>
  <titles>
    <title>The Origins of SARS-CoV-2: A Critical Review</title>
  </titles>
  <publisher>Zenodo</publisher>
  <publicationYear>2021</publicationYear>
  <subjects>
    <subject>sars-cov-2</subject>
    <subject>covid-19</subject>
    <subject>origins</subject>
    <subject>zoonosis</subject>
  </subjects>
  <dates>
    <date dateType="Issued">2021-07-07</date>
  </dates>
  <resourceType resourceTypeGeneral="Preprint"/>
  <alternateIdentifiers>
    <alternateIdentifier alternateIdentifierType="url">https://zenodo.org/record/5075888</alternateIdentifier>
  </alternateIdentifiers>
  <relatedIdentifiers>
    <relatedIdentifier relatedIdentifierType="DOI" relationType="IsVersionOf">10.5281/zenodo.5075887</relatedIdentifier>
    <relatedIdentifier relatedIdentifierType="URL" relationType="IsPartOf">https://zenodo.org/communities/sars-cov-2-origins</relatedIdentifier>
  </relatedIdentifiers>
  <version>1.0</version>
  <rightsList>
    <rights rightsURI="https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode">Creative Commons Attribution Non Commercial No Derivatives 4.0 International</rights>
    <rights rightsURI="info:eu-repo/semantics/openAccess">Open Access</rights>
  </rightsList>
  <descriptions>
    <description descriptionType="Abstract">&lt;p&gt;The Origins of SARS-CoV-2: A Critical Review&lt;/p&gt;

&lt;p&gt;Holmes et al.&lt;/p&gt;

&lt;p&gt;Since the first reports of a novel SARS-like coronavirus in December 2019 in Wuhan, China, there has been intense interest in understanding how SARS-CoV-2 emerged in the human population. Recent debate has coalesced around two competing ideas: a &amp;ldquo;laboratory escape&amp;rdquo; scenario and zoonotic emergence. Here, we critically review the current scientific evidence that may help clarify the origin of SARS-CoV-2.&lt;/p&gt;

&lt;p&gt;&amp;nbsp;&lt;/p&gt;</description>
  </descriptions>
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