Journal article Open Access
M Rodríguez Sánchez; Bassi AP; Carvalho PS
{ "description": "<p>Bisphosphonates toxicological effect on alveolar bone could be associated to medication related osteonecrosis of the jaw. (MRONJ) Oral surgical procedures as; tooth extractions, implants placements or trauma are suggested risk factors. The aim of this paper is to describe a case of MRONJ and recurrence after the first right mandibular molar extraction. A 54 years old man was referred to the Department of Surgery and Integrated Clinic of Aracatuba Dental School, Univ. Estadual Paulista - UNESP with a medical history of myeloma multiple and treated with zoledronic acid during 3 years. Her dental history consisted of a mandibular molar extraction 3 years after having finished zoledronic acid intake. After the dental extraction the patient developed a clinical features of MRONJ that was treated with antibiotics, sequestrectomy, hyperbaric oxygen, with apparently total resolution for about five month. The post-operative 6th month the patient complained of recurrent pain, exudates and swelling. Antibiotic were prescribed in addition to surgical debridement. Even though mucosal<br />\ncoverage was achieved during the second surgical procedures, healing occurred without signs of infection but without complete gingival coverage until the second year postoperative. MRONJ is a challenge complication and there is not a gold<br />\nstandard treatment.</p>", "license": "https://creativecommons.org/licenses/by/4.0/legalcode", "creator": [ { "affiliation": "Postgraduate Student, Department of Surgery and Integrated Clinics, Aracatuba Dental School, Sao Paulo State University, Brazil", "@type": "Person", "name": "M Rodr\u00edguez S\u00e1nchez" }, { "affiliation": "Professor at Aracatuba Dental School, Department of Surgery and Integrated Clinics, Sao Paulo State University, Aracatuba SP, Brazil", "@type": "Person", "name": "Bassi AP" }, { "affiliation": "Professor at Bauru Dental School, Department of Stomatology, Sao Paulo State University, Bauru SP, Brazil.", "@type": "Person", "name": "Carvalho PS" } ], "headline": "The Challenge Treatment of Medication Related Osteonecrosis of the Jaw: A Case Report", "image": "https://zenodo.org/static/img/logos/zenodo-gradient-round.svg", "datePublished": "2015-07-06", "url": "https://zenodo.org/record/47167", "keywords": [ "Osteonecrosis of the Jaw", "Oral Surgery", "Tooth Extraction", "Bisphosphonates" ], "@context": "https://schema.org/", "identifier": "https://doi.org/10.19070/2377-8075-1500022", "@id": "https://doi.org/10.19070/2377-8075-1500022", "@type": "ScholarlyArticle", "name": "The Challenge Treatment of Medication Related Osteonecrosis of the Jaw: A Case Report" }
Views | 42 |
Downloads | 38 |
Data volume | 47.6 MB |
Unique views | 42 |
Unique downloads | 38 |