Journal article Open Access
M Rodríguez Sánchez; Bassi AP; Carvalho PS
<?xml version='1.0' encoding='utf-8'?> <resource xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns="http://datacite.org/schema/kernel-4" xsi:schemaLocation="http://datacite.org/schema/kernel-4 http://schema.datacite.org/meta/kernel-4.1/metadata.xsd"> <identifier identifierType="URL">https://zenodo.org/record/47167</identifier> <creators> <creator> <creatorName>M Rodríguez Sánchez</creatorName> <affiliation>Postgraduate Student, Department of Surgery and Integrated Clinics, Aracatuba Dental School, Sao Paulo State University, Brazil</affiliation> </creator> <creator> <creatorName>Bassi AP</creatorName> <affiliation>Professor at Aracatuba Dental School, Department of Surgery and Integrated Clinics, Sao Paulo State University, Aracatuba SP, Brazil</affiliation> </creator> <creator> <creatorName>Carvalho PS</creatorName> <affiliation>Professor at Bauru Dental School, Department of Stomatology, Sao Paulo State University, Bauru SP, Brazil.</affiliation> </creator> </creators> <titles> <title>The Challenge Treatment of Medication Related Osteonecrosis of the Jaw: A Case Report</title> </titles> <publisher>Zenodo</publisher> <publicationYear>2015</publicationYear> <subjects> <subject>Osteonecrosis of the Jaw</subject> <subject>Oral Surgery</subject> <subject>Tooth Extraction</subject> <subject>Bisphosphonates</subject> </subjects> <dates> <date dateType="Issued">2015-07-06</date> </dates> <resourceType resourceTypeGeneral="Text">Journal article</resourceType> <alternateIdentifiers> <alternateIdentifier alternateIdentifierType="url">https://zenodo.org/record/47167</alternateIdentifier> </alternateIdentifiers> <relatedIdentifiers> <relatedIdentifier relatedIdentifierType="DOI" relationType="IsIdenticalTo">10.19070/2377-8075-1500022</relatedIdentifier> </relatedIdentifiers> <rightsList> <rights rightsURI="https://creativecommons.org/licenses/by/4.0/legalcode">Creative Commons Attribution 4.0 International</rights> <rights rightsURI="info:eu-repo/semantics/openAccess">Open Access</rights> </rightsList> <descriptions> <description descriptionType="Abstract"><p>Bisphosphonates toxicological effect on alveolar bone could be associated to medication related osteonecrosis of the jaw.&nbsp;(MRONJ) Oral surgical procedures as; tooth extractions, implants placements or trauma are suggested risk factors. The aim&nbsp;of this paper is to describe a case of MRONJ and recurrence after the first right mandibular molar extraction. A 54 years&nbsp;old man was referred to the Department of Surgery and Integrated Clinic of Aracatuba Dental School, Univ. Estadual&nbsp;Paulista - UNESP with a medical history of myeloma multiple and treated with zoledronic acid during 3 years. Her dental&nbsp;history consisted of a mandibular molar extraction 3 years after having finished zoledronic acid intake. After the dental&nbsp;extraction the patient developed a clinical features of MRONJ that was treated with antibiotics, sequestrectomy, hyperbaric&nbsp;oxygen, with apparently total resolution for about five month. The post-operative 6th month the patient complained of&nbsp;recurrent pain, exudates and swelling. Antibiotic were prescribed in addition to surgical debridement. Even though mucosal<br /> coverage was achieved during the second surgical procedures, healing occurred without signs of infection but without&nbsp;complete gingival coverage until the second year postoperative. MRONJ is a challenge complication and there is not a gold<br /> standard treatment.</p></description> </descriptions> </resource>
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