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Published April 8, 2021 | Version v1
Dataset Open

Multi-parameter photon-byphoton hidden Markov modeling dataset

  • 1. Department of Biological Chemistry, The Alexander Silberman Institute of Life Sciences, The Edmond J. Safra Campus, The Hebrew University of Jerusalem
  • 2. Department ofChemistry and Biochemistry, University ofCalifornia, Los Angeles

Description

The core jupyter notebooks demonstrating mpH2MM using real nsALEX data on DNA hairpin and theRNAP complex with the RPo transcription bubble. Also included are the jupyter notebooks for generating simulated photon trajectories to test the validity of the Integrated complete likelihood (ICL) on data where the ground truth is known.

Included are all HDF5 files used by the jupyter notebooks, as well as .csv files containing all H2MM models generated during the processing of the data.

Files

1. Simulate 3D trajectories - 600s.ipynb

Files (347.8 MB)

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