CNS TUBERCULOSIS AND STROKE, BURDEN, MANAGEMENT CHALLENGES AND FUTURE NEEDS FOR CARE AND RESEARCH

Introduction: Tuberculosis is an ancient disease that is known to have existed in prehistoric times. Tuberculosis is one of the commonest communicable diseases in a majority of the developing countries. Objectives: The main objective of the study is to analyse the CNS tuberculosis and stroke, burden, management challenges and future needs for care and research. Material and methods: This cross-sectional study was conducted in Civil hospital Karachi during 2019-2020. In this study 55 patients age range 1 to 5 years suspected of having tuberculosis meningitis were included in the study. The 5cc blood was taken for the analysis of further biochemical test. Results: A total 55 patients were included in the study. Out of these 55 patients 32 patients were in highly probable TBM group and 18 cases in group II (Probable TBM) and 5 patients belonged to group III (Possible TBM). Out of these 55 patients 27(50.94%) patients were male and 26 (49.05%) female. This study was conducted in age groups 2 month to 14 years. Table 01 shows the basic biochemical profile of these 55 patients. Conclusion: It is concluded that hematological and biochemistry parameters are important, simple, and cheaper method in analyzing the pattern of health status among TB patients.