A BRIEF OVERVIEW ON LIVER CIRRHOSIS

Cirrhosis is a complication of liver disease and leading cause of morbidity and mortality around the world. Chronic liver diseases represent a crucial health problem across the globe with liver cirrhosis. It is characterized by the formation of regenerative nodules in liver parenchyma enclosed by fibrous septa and loss of liver cells and irreversible scarring of the liver because of chronic liver injury. Cirrhosis of liver always occurs due to necrosis of liver cells followed by fatty liver and fibrosis. The liver structure becomes abnormal and involved with liver blood flow and perform that leads to portal hypertension, Hepatic encephalopathy and impaired hepatocytes performance. Chronic liver diseases represent a crucial health problem across the globe with liver cirrhosis. However, treatment of cirrhosis is designed to prevent further damage to the liver, treat complications of cirrhosis the recent advances within the identification, diagnosis and treatment of chronic liver diseases have changed the treatment history of cirrhosis significantly. Diagnosis of cirrhosis based how badly your liver is injured that includes serological test, and radio techniques like ultrasonography, and magnetic resonance imaging. Ursodeoxycholic acid has anti-apoptotic action that is used for treatment of primary biliary cirrhosis. Silymarin (Silybum marianum) acts as a free radical scavenger, reduces the inflammatory reaction and also modulates enzymes associated with the development of cellular damage, fibrosis and cirrhosis.

Keywords: Liver cirrhosis, Complications, multiple cell types, Radio Techniques, Ursodeoxycholic acid and Silymarin.