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Aquatic Mixture Toxicity Tool and additional Information

Hillebrand, Marcus; Duquesne, Sabine; Aagard, Alf; Kraemer, Wolfgang; HAUGE SKARSJO, Mathilde; Zorn, Mathilde; Pedersen, Signe; Trobej, Manuela; Gassner-Schneckenleithner, Christoph; Egerer, Sina; Frishe, Tobias

This “AGD_AquaMix_v1.15”  is a tool for the calculation of Aquatic Mixture Toxicity for the environmental risk assessment of plant protection products containing a combination of active substances, as addressed in section 10.3 of the Guidance on tiered risk assessment for edge-of-field surface waters (EFSA Journal 2013;11(7):3290).

This tool has been developed as an initiative of a few regulators from different member states. It is an Excel document composed of different worksheets:

  • “Intro” and Overview” are for general information,
  •  “Input Tox” and “Input PEC”  are for entering the input data,
  • “Step 1” to “Step 10” follow the decision scheme for mixture toxicity risk assessment described in section 10.3.11. of the Aquatic Guidance Document (AGD),
  • “Final conclusion” is for summarising the outcomes of the calculations and “in-between_calc” presents intermediate calculation steps.

It is accompanied by a document so-called “FAQ_MixedTox_v1”, proposing approaches and recommendations on Frequently Asked Questions in the context of the aquatic Mixture Toxicity (e.g. metabolites, use of different FOCUS steps).

DE; Excel; Sabine.Duquesne@uba.de
Files (2.0 MB)
Name Size
AGD_AquaMix_v1.15.xlsm
md5:47e4616fbe930a3d3c4414fd6f1415aa
1.4 MB Download
FAQ_ AquaticMixedTox_v1.pdf
md5:3dd9b6a8710fc7dd9c7543a78c680662
590.4 kB Download
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