a ; "Academy Research Fellowships TT"; "0"; "0.0"; "Academy of Finland"; "Identication and Functional Analysis of Novel Asthma Genes- A Basis for New Diagnostics and Therapeutics in Pulmonary Medicine"; "2019-01-25"; "2003-07-31"; "2020-10-01"; "EUR"; "2002-08-01"; ; "79830.0". a ; "Postdoctoral Researcher LT"; "0"; "0.0"; "Academy of Finland"; "Joint Adaptation of Multiple Cognitive Systems without Explicit Coordination"; "2019-01-25"; "2016-08-31"; "2020-10-01"; "EUR"; "2013-09-01"; ; "251990.0". a ; "Ulkomaisten tutkijoiden työskentely Suomessa BY"; "0"; "0.0"; "Academy of Finland"; "Invitation of Russian Researcher to Finland; O. Galanina"; "2019-01-25"; "2006-12-31"; "2020-10-01"; "EUR"; "2005-02-14"; ; "15720.0". a ; ; ; ; ; ; ; ; "Academy of Finland"; "DAGIS Increased health and wellbeing in Preschool / Consortium: Dagis- terveyden ja hyvinvoinnin edistäminen päivä"; "EUR"; ; "Academy Project TT"; "0"; "0.0"; "2019-01-25"; "2018-08-31"; "2020-10-01"; "2015-09-01"; "126021.0". a ; ; ; ; ; ; ; "Academy of Finland"; "Membrane biology of cholesterol: from basic research to personalized applications"; "EUR"; ; "Funding for research expenses for an Academy professor 2015-2017 TT"; "0"; "0.0"; "2019-01-25"; "2017-12-31"; "2020-10-01"; "2015-01-01"; "749184.0". a ; ; ; ; ; ; "Academy of Finland"; "Atmosphere-hydrosphere interaction in the Baltic Basin and Arctic Seas (ABBA)"; "EUR"; ; "Joint projects: Geosciences (Academy of Finland and RFBR, Russia) LT"; "0"; "0.0"; "2019-01-25"; "2017-08-31"; "2020-10-01"; "2014-09-01"; "373825.0". a ; "Research costs of Academy Research Fellows TT"; "0"; "0.0"; "Academy of Finland"; "The epidemiology, risk factors, and developmental precursors of psychotic disorders"; "2019-01-25"; "2008-12-31"; "2020-10-01"; "EUR"; "2006-08-01"; ; "145000.0". a ; "Postdoctoral Researcher's project TT"; "0"; "0.0"; "Academy of Finland"; "Ligand structure-activity relationships of MDR-1, BCRP and polymorphic forms: Tools for early drug discovery"; "2019-01-25"; "2012-12-31"; "2020-10-01"; "EUR"; "2009-01-01"; ; "195450.0". a ; "Määrärahat tutkijatohtorien palkkaamiseen / elinkeinoelämä LT"; "0"; "0.0"; "Academy of Finland"; "Influence of the streamline boundary layer and wall shear stress on the cleaning efficiency"; "2019-01-25"; "2005-12-31"; "2020-10-01"; "EUR"; "2003-08-01"; ; "100000.0". a ; "Yleiset tutkimusmäärärahat TT"; "0"; "0.0"; "Academy of Finland"; "Vitamin D and Type 1 Diabetes"; "2019-01-25"; "2011-12-31"; "2020-10-01"; "EUR"; "2009-01-01"; ; "210000.0". a ; "Tutkijainvaihto Suomeen KY"; "0"; "0.0"; "Academy of Finland"; "Historical and contemporary investigations of family in Finland and Scandinavia"; "2019-01-25"; "2005-12-31"; "2020-10-01"; "EUR"; "2005-05-17"; ; "240.0". a ; "Academy Research Fellows: initial funding for research costs, invited applicants only BY"; "0"; "0.0"; "Academy of Finland"; "Towards Understanding the Impact of Climate Change on Eurasian Boreal Forests: a Novel Stable Isotope Approach"; "2019-01-25"; "2019-08-31"; "2020-10-01"; "EUR"; "2016-09-01"; ; "272028.0". a ; "Virkapäätöksiin liittyvä yleiskustannusosuus LT"; "0"; "0.0"; "Academy of Finland"; "Tutkijan virkaan liittyvä yleiskustannusosuus suorituspaikalle"; "2019-01-25"; "2002-12-31"; "2020-10-01"; "EUR"; "2002-12-09"; ; "2440.0". a ; "Tutkijoiden liikkuvuus - Suomeen BY"; "0"; "0.0"; "Academy of Finland"; "Joint Finnish-Czech Symposium"; "2019-01-25"; "2006-12-31"; "2020-10-01"; "EUR"; "2006-10-24"; ; "350.0". a ; "Academy Professor, stage 2 (invited applicants only) LT"; "0"; "0.0"; "Academy of Finland"; "Non-linear inverse problems and the mathematics of imaging"; "2019-01-25"; "2023-12-31"; "2020-10-01"; "EUR"; "2019-01-01"; ; "781195.0". a ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; "Academy of Finland"; "Synthetic controllability of biological networks through understanding and engineering their control elements / Consortium: CONTROL"; "EUR"; ; "FinSynBio 2013 LT"; "0"; "0.0"; "2019-01-25"; "2017-08-31"; "2020-10-01"; "2013-09-01"; "337642.0". a ; "Työelämässä olevien henkilöiden jatkokoulutus KY"; "0"; "0.0"; "Academy of Finland"; "The Impact of Value-Added taxation on Growth and Employment"; "2019-01-25"; "2006-12-31"; "2020-10-01"; "EUR"; "2005-05-20"; ; "34980.0". a ; "Work of foreign researchers in Finland TT"; "0"; "0.0"; "Academy of Finland"; "Search for novel susceptibility genes for colon cancer"; "2019-01-25"; "2005-12-31"; "2020-10-01"; "EUR"; "2004-08-01"; ; "10000.0". a ; "FEMTOSTACK"; "0"; "0.0"; "Agence Nationale de la Recherche"; "NEW TOOLS BASED ON ULTRAFAST SPECTROSCOPY AND MOLECULAR DYNAMICS SIMULATION FOR INVESTIGATING THE STRUCTURAL DYNAMICS OF CHAPERON PROTEIN/DNA COMPLEXES"; "2019-12-24"; "2020-11-19"; "0.0". a ; "SOMBRERO"; "0"; "0.0"; "Agence Nationale de la Recherche"; "EMBODYING SOCIO-COMMUNICATIVE BEHAVIORS IN HUMANOID ROBOTS"; "2019-12-24"; "2020-11-19"; "0.0". a ; "DESAM"; "0"; "0.0"; ; "Agence Nationale de la Recherche"; "DÉCOMPOSITION EN ELÉMENTS SONORES ET APPLICATIONS MUSICALES"; "2019-12-24"; "2020-11-19"; "0.0". a ; "CODENUM"; "0"; "0.0"; "Agence Nationale de la Recherche"; "DISTINGUISHING NUMERICAL CODES IN THE HUMAN BRAIN WITH HIGH-FIELD IMAGING"; "2019-12-24"; "2020-11-19"; "0.0". a ; "RHYTHMDEV"; "0"; "0.0"; "Agence Nationale de la Recherche"; "EMBRYONIC DEVELOPMENT OF RHYTHMOGENIC MOTOR NETWORKS"; "2019-12-24"; "2020-11-19"; "0.0". a ; "IGLIAS"; "0"; "0.0"; ; ; ; "Agence Nationale de la Recherche"; "IRRADIATION OF ASTROPHYSICAL ICES"; "2019-12-24"; "2020-11-19"; "0.0". a ; "NICE CROPS"; "0"; "0.0"; "Agence Nationale de la Recherche"; "NATURAL CHITIN-RELATED BIO-STIMULATORS FOR SUSTAINABLE AGRICULTURE"; "2019-12-24"; "2020-11-19"; "0.0". a ; "UV-CHALLENGE"; "0"; "0.0"; ; "Agence Nationale de la Recherche"; "NEW NON LINEAR OPTICAL CRYSTALS FOR UV: BEYOND THE LIMITS FOR RELIABLE SOLID STATE LASER SYSTEMS."; "2019-12-24"; "2020-11-19"; "0.0". a ; ; "0"; "0.0"; ; ; "Discovery Early Career Researcher Award - Grant ID: DE140101749"; "2015-08-24"; "computational linguistics,language acquisition,semantic memory"; "2016-12-31"; "2018-11-20"; "2014-01-01"; "0.0". a ; ; "0"; "0.0"; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; "Discovery Projects - Grant ID: DP130102420"; "2015-08-24"; "carbon nanohybrid,catalyst,denisty functional theory"; "2015-12-31"; "2018-11-20"; "2013-01-01"; "0.0". a ; ; "0"; "0.0"; ; ; "Discovery Projects - Grant ID: DP130104587"; "2015-08-24"; "data mining,databases,indexing"; "2015-12-31"; "2018-11-20"; "2013-01-01"; "0.0". a ; ; "0"; "0.0"; ; ; ; ; ; ; ; ; ; "Linkage Projects - Grant ID: LP130100361"; "2015-08-24"; "bioenergy,sludge,wastewater"; "2016-12-31"; "2018-11-20"; "2013-01-01"; "0.0". a ; ; "0"; "0.0"; ; ; ; ; ; ; "Harnessing symmetry to advance the study of graphs"; "2015-08-24"; "algebraic graph theory,group theory,permutation groups"; "2014-12-31"; "2018-11-20"; "2012-01-01"; "0.0". a ; ; "0"; "0.0"; ; ; ; ; ; "Unpacking the effects of stimulus exposure in human learning"; "2015-08-24"; "associative learning,attention,discrimination learning"; "2014-12-31"; "2018-11-20"; "2012-01-01"; "0.0". a ; ; "0"; "0.0"; ; ; ; ; ; ; ; "Linkage Projects - Grant ID: LP140100874"; "2015-08-24"; "GEOCHRONOLOGY; GEOCHRONOLOGY; PETROLOGY; PETROLOGY; TECTONICS; TECTONICS; TECTONICS"; "2017-12-31"; "2018-11-20"; "2014-01-01"; "0.0". a ; ; "0"; "0.0"; ; ; ; ; ; ; "Discovery Projects - Grant ID: DP140100203"; "2015-08-24"; "complex dynamical systems,nonlinear time series,social networks"; "2016-12-31"; "2018-11-20"; "2014-01-01"; "0.0". a ; ; "0"; "0.0"; ; ; ; "From Paddy to Pura: the origins of Angkor"; "2015-08-24"; "archaeology,cambodia,thailand,trade and exchange"; "2013-12-31"; "2018-11-20"; "2011-01-01"; "0.0". a ; ; "0"; "0.0"; ; ; "Discovery Projects - Grant ID: DP150102580"; "2015-08-24"; "PHOTOSYNTHETIC LIGHT HARVESTING; PROTEIN CRYSTALLOGRAPHY; STRUCTURAL BIOLOGY"; "2017-12-31"; "2018-11-20"; "2015-01-01"; "0.0". a ; ; "0"; "0.0"; ; ; ; ; ; ; ; ; ; ; ; ; ; ; "Discovery Projects - Grant ID: DP170100131"; "2017-08-07"; "2023-12-31"; "2019-09-02"; "2017-01-01"; "0.0". a ; ; "0"; "0.0"; ; "Understanding Indonesian: developing a machine-usable grammar, dictionary and corpus"; "2015-08-24"; "computational linguistics,indonesian language,lexical functional grammar,lexicon,linguistics,syntax"; "2010-12-31"; "2018-11-20"; "2008-01-01"; "0.0". a ; ; ; ; ; "CORDA - COmmon Research DAta Warehouse"; "GENeric European Sustainable Information Space for Environment"; "Raoust, Jean-Paul"; "CP"; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; "FP7-ICT-2007-2"; "GENESIS"; "0"; "0.0"; "2018-03-12"; "2011-08-31"; "2020-06-26"; "2008-09-01"; "0.0". a ; ; ; ; ; ; "CORDA - COmmon Research DAta Warehouse"; "Nonlinear Optics and Lasing in Complex Media"; "Rotter, Stefan"; "MC"; ; "FP7-PEOPLE-2011-IOF"; "NOLACOME"; "0"; "0.0"; "2018-03-12"; "2015-05-31"; "2020-06-26"; "2012-06-01"; "0.0". a ; ; "CORDA - COmmon Research DAta Warehouse"; "Photoelectron Imaging and Spectroscopy of biomolecules using VUV light"; "Rosati, Fosca"; "MC"; ; "FP7-PEOPLE-ERG-2008"; "IMAGINGELECTRONS"; "0"; "0.0"; "2018-03-12"; "2011-10-31"; "2020-06-26"; "2008-11-01"; "0.0". a ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; "CORDA - COmmon Research DAta Warehouse"; "Awareness and Migration: Organizations for bi-national family Rights Empowerment"; "Courillon, Christine"; "MC"; ; "FP7-PEOPLE-2013-IEF"; "AMORE"; "0"; "0.0"; "2018-03-12"; "2016-06-30"; "2020-06-26"; "2014-07-01"; "0.0". a ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; "CORDA - COmmon Research DAta Warehouse"; "Rural Landscape in north-eastern Roman Gaul"; "Thariat, Marie"; "ERC"; ; "ERC-2013-ADG"; "RURLAND"; "0"; "0.0"; "2018-03-12"; "2018-04-30"; "2020-06-26"; "2014-02-01"; "0.0". a ; "CORDA - COmmon Research DAta Warehouse"; "An open simulation environment for self-diagnosis and prognosis in composite aero-structures"; "Bofilios, Dimitri"; "171"; ; ; ; "SP1-JTI-CS-2009-01"; "SENCES"; "0"; "0.0"; "2018-03-12"; "2013-03-31"; "2020-06-26"; "2009-11-01"; "0.0". a ; "CORDA - COmmon Research DAta Warehouse"; "Demonstration of an adaptable structure for architecture applications"; "Felipe Marzal, Sylvia"; "CP"; ; ; ; ; ; ; ; ; ; "FP7-SME-2013"; "HYPERMEMBRANE-DEMO"; "0"; "0.0"; "2018-03-12"; "2016-07-31"; "2020-06-26"; "2014-01-01"; "0.0". a ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; "CORDA - COmmon Research DAta Warehouse"; "Polymer - Carbon Nanotubes Active Systems for Photovoltaics"; "Villa, Maria Jesus"; "MC"; ; ; ; ; ; ; ; ; ; ; "FP7-PEOPLE-2012-ITN"; "POCAONTAS"; "0"; "0.0"; "2018-03-12"; "2016-10-31"; "2020-06-26"; "2012-11-01"; "0.0". a ; "CORDA - COmmon Research DAta Warehouse"; "Towards a fully quantum ab initio treatment of chemical reactions at solid surfaces"; "Browne, Michael"; "ERC"; ; "ERC-2007-StG"; "QUANTUMCRASS"; "0"; "0.0"; "2018-03-12"; "2012-07-31"; "2020-06-26"; "2008-08-01"; "0.0". a ; ; "CORDA - COmmon Research DAta Warehouse"; "RETROFITting ships with new technologies for improved overall environmental footprint"; "Krikke, Marnix"; "CP"; ; ; ; ; ; ; ; ; ; ; ; ; ; ; "FP7-SST-2011-RTD-1"; "RETROFIT"; "0"; "0.0"; "2018-03-12"; "2015-01-31"; "2020-06-26"; "2011-10-01"; "0.0". a ; "CORDA - COmmon Research DAta Warehouse"; "Geographic diversity of Neandertals in Europe"; "Jiménez Arroyo, Eusebio"; "MC"; ; "FP7-PEOPLE-2010-IEF"; "NEAND-GEOGR-DIV"; "0"; "0.0"; "2018-03-18"; "2012-01-31"; "2020-06-26"; "2011-07-01"; "0.0". a ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; "CORDA - COmmon Research DAta Warehouse"; "Functionalities of Bismuth based nanostructures"; "Grosu, Veaceslav"; "CP"; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; "FP7-NMP-2010-EU-Mexico"; "BISNANO"; "0"; "0.0"; "2018-03-12"; "2013-09-30"; "2020-06-26"; "2010-10-01"; "0.0". a ; "CORDA - COmmon Research DAta Warehouse"; "Coordination Action for Reinforcing the Health National Contact Points Network"; "Barrionuevo, Marta"; "CSA"; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; "FP7-HEALTH-2007-A"; "HEALTH-NCP-NET"; "0"; "0.0"; "2018-03-12"; "2013-04-30"; "2020-06-26"; "2008-05-01"; "0.0". a ; ; ; ; "CORDA - COmmon Research DAta Warehouse"; "Advanced Technologies for Biogas Efficiency Sustainability and Transport"; "Mccloskey, Sam"; "MC"; ; ; ; ; ; ; ; ; ; "FP7-PEOPLE-2012-ITN"; "ATBEST"; "0"; "0.0"; "2018-03-12"; "2017-06-30"; "2020-06-26"; "2013-07-01"; "0.0". a ; "CORDA - COmmon Research DAta Warehouse"; "Carbohydrate utilization by the working muscle of rainbow trout"; "Frasch, Alberto Carlos C."; "MC"; ; "FP7-PEOPLE-IIF-2008"; "GLUCOSE USE IN FISH"; "0"; "0.0"; "2018-03-12"; "2013-10-31"; "2020-06-26"; "2012-03-01"; "0.0". a ; ; "CORDA - COmmon Research DAta Warehouse"; "Clinical Application for Metabolic Profiling"; "Heise, Tim"; "BSG"; ; ; ; ; ; ; ; "FP7-SME-2010-1"; "EU-CLAMP"; "0"; "0.0"; "2018-03-12"; "2012-11-30"; "2020-06-26"; "2010-12-01"; "0.0". a ; "CORDA - COmmon Research DAta Warehouse"; "European Union Contest for Young Scientists 2012"; "Sipos, Jan"; "CSA"; ; "FP7-Adhoc-2007-13"; "EUCYS 2012"; "0"; "0.0"; "2018-03-12"; "2013-01-09"; "2020-06-26"; "2012-01-10"; "0.0". a ; "FP7-PEOPLE-2012-IIF"; "RADIOTRANSIENTS"; "0"; "0.0"; "CORDA - COmmon Research DAta Warehouse"; "Detecting and characterizing radio transients"; "2018-03-12"; "Woudt, Patrick"; "2020-06-26"; "MC"; ; "0.0". a ; ; ; ; ; ; ; ; ; ; ; "CORDA - COmmon Research DAta Warehouse"; "MEMS Tuneable Metamaterials for Smart Wireless Applications"; "CP"; ; ; ; ; ; ; "FP7-ICT-2007-2"; "TUMESA"; "0"; "0.0"; "2018-03-12"; "2011-09-30"; "2020-06-26"; "2008-06-01"; "0.0". a ; ; ; ; ; ; ; ; ; ; "CORDA - COmmon Research DAta Warehouse"; "Trans-Atlantic Imaging of Lithosphere Asthenosphere Boundary"; "Metzelard, Frédérique"; "ERC"; ; "ERC-2013-ADG"; "TRANSATLANTICILAB"; "0"; "0.0"; "2018-03-12"; "2020-12-31"; "2020-08-16"; "2014-11-01"; "0.0". a ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; "CORDA - COmmon Research DAta Warehouse"; "Families in context: Unraveling the ways in which policy, economic, and cultural contexts structure generational interdependencies in families and their life outcomes"; "Heeres, Patrick"; "ERC"; ; "ERC-2012-ADG_20120411"; "FAMILIES IN CONTEXT"; "0"; "0.0"; "2018-03-12"; "2018-04-30"; "2020-06-26"; "2013-05-01"; "0.0". a ; "CORDA - COmmon Research DAta Warehouse"; "Polypterids – development and evolution of a ’living fossil’"; "Duffin, Kristina"; "MC"; ; "FP7-PEOPLE-2007-2-1-IEF"; "POLYPTERUS EVO-DEVO"; "0"; "0.0"; "2018-03-12"; "2010-02-14"; "2020-06-26"; "2008-10-15"; "0.0". a ; "CORDA - COmmon Research DAta Warehouse"; "Biophysical mechanisms regulating early T cell signalling events"; "Labbett, Paul"; "MC"; ; "FP7-PEOPLE-2012-CIG"; "BIOPHIS"; "0"; "0.0"; "2018-03-12"; "2017-02-28"; "2020-06-26"; "2013-03-01"; "0.0". a ; "Excellent science | European Research Council (ERC)"; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; "CORDA - COmmon Research DAta Warehouse - Horizon 2020"; "Mechanisms and Consequences of Attributing Socialness to Artificial Agents"; "Cross, Emily"; "EUR"; "ERC-STG"; ; ; "ERC-2015-STG"; "SOCIAL ROBOTS"; "0"; "H2020-EU.1.1."; "1809000.0"; "Excellent Science"; "Understanding how we perceive and interact with others is a core challenge of social cognition research. This challenge is poised to intensify in importance as the ubiquity of artificial intelligence and the presence of humanoid robots in society grows. By innovatively combining psychology, neuroscience and robotics, the SOCIAL ROBOTS project helps prepare us for this future by (1) establishing a new approach for understanding how the human brain processes and responds to interactive robots; (2) delineating the factors influencing how representations of robots and humans are shared at brain and behavioural levels; and (3) exploring how these findings inform the now-rapid development of social robots. To achieve this, we first investigate how young adults perceive and interact with humans vs. robots, the role of physical features and training experience, and the extent to which brain regions mediating social interaction with humans also support robot interaction. Next, to test the role of experience-dependent plasticity on social cognition, we assess how brain and behavioural flexibility toward robots manifests among young children and older adults. Finally, we explore cultural influences on shared representations of humans and robots by extending the first project phase to Japan, the world’s most robotics-rich nation. The SOCIAL ROBOTS project tests a dominant hypothesis of social cognition and is expected to lead to a novel conception of the neurocognitive architecture supporting human-robot interaction. Neuroimaging and behavioural measures will offer detailed and nuanced insights into how brain mechanisms supporting social engagement with people are used when interacting with robots, and how different kinds of experience (e.g., training, lifespan, cultural) influence such engagement. The planned studies and those generated during the project will enable the SOCIAL ROBOTS team to become a world-leading group bridging social cognition, neuroscience and robotics."; "2018-03-12"; "European Research Council (ERC)"; "2021-09-30"; "ERC Starting Grant"; "2020-11-28"; "2016-10-01"; "1809000.0". a ; "Industrial leadership | Leadership in enabling and industrial technologies | Information and Communication Technologies (ICT)"; "CORDA - COmmon Research DAta Warehouse - Horizon 2020"; "Hubble – smart workplace allocation platform"; "BHANOT, Varun"; "EUR"; "SME-1"; ; "H2020-SMEINST-1-2016-2017"; "Hubble"; "0"; "H2020-EU.2.1.1."; "71429.0"; "Industrial Leadership"; "Hubble is a breakthrough SaaS platform which intermediates between SMEs searching for commercial real estate and providers with available property by offering a marketplace for commercial real estate to help manage the renting of excess capacity within offices and flexible service providers. Hubble provides best-class usability to find the right location quickly, and through the use of clear online contracts and payments, processed and recorded on the platform, adds unprecedented transparency to an otherwise, very opaque industry. The platform is disrupting the market by filling the gap left by traditional real estate agents, who are failing SMEs due to a lack of incentive and dependence on legacy business models and offers direct, tangible economic benefits to its target customers, by improving speed, reducing costs and increasing transparency. Hubble helps lower the barriers for new businesses, helps companies share office space and reduce their cost base, makes office space more affordable. Overall, the European economy benefits from more favorable business establishment conditions, more productive use of existing real estate assets, and job creation.In January 2017, Hubble counts 1,500+ registered offices, 20,000 desks mostly focused in the London area, which is approximately 2,5% of the local market, with a monthly revenue of £40K, generating a total of £500K in annualized revenue. The company has so far focused on the London market. It now wishes to expand into key cities across Europe and beyond. To enable this, the company is applying to undertake a six-month feasibility study through the Horizon 2020 SME Instrument Phase 1. The study will include a user review to assess needs and take-up, a technology review to enhance the product, marketing and sales analysis to test practical approaches, financial review to check assumptions and risks, an IPR review into patentability, and a full business plan to prepare for further financing."; "2019-11-11"; "Information and Communication Technologies"; "Leadership in enabling and industrial technologies (LEIT)"; "2017-09-30"; "Open Disruptive Innovation Scheme"; "2020-11-28"; "2017-04-01"; "50000.0". a ; "Excellent science | European Research Council (ERC)"; "CORDA - COmmon Research DAta Warehouse - Horizon 2020"; "ThermoacOustic instabilities contRol in sequential Combustion cHambers"; "NOIRAY, Nicolas"; "EUR"; "ERC-COG"; ; "ERC-2018-COG"; "TORCH"; "0"; "H2020-EU.1.1."; "2585170.0"; "Excellent Science"; "A new type of combustor architecture for large gas turbines has emerged in recent years: sequential combustion systems operated at constant pressure. This major technology change results from the need for more operationally and fuel flexible gas turbines, for future sustainable energy networks. As for regular gas turbines, the risk of combustor breakdown due to thermoacoustic instabilities is a major challenge. While the harmful consequences of these instabilities in novel sequential combustors can be as dramatic as in conventional systems, the associated physics is considerably complexified, because the two flames not only “talk” together via sound waves, but also via entropy waves. Our aim is to propose, investigate and develop novel active and passive control technologies, tailored for this new generation of combustors, in order to suppress their thermoacoustic instabilities. It brings significant scientific challenges in fluid mechanics, acoustics, combustion, nonlinear dynamics and control theory. We will address the problem of controlling these instabilities on two unexplored fronts: First, we intend to significantly move forward the state-of-the-art in passive control of combustion instabilities, by creating acoustic metamaterials with unprecedented acoustic damping properties, and capable of long term operation in harsh environments. Second, we plan to address scientific challenges, required to successfully achieve active combustion control in sequential combustors, by distributing non-equilibrium plasma discharges to locally and dynamically enhance the autoignition chemistry. To achieve these ambitious goals, a combination of experimental, numerical and theoretical methods will be applied with the aim to ultimately establish the potential and limitations of these novel technologies. This research deals with new areas in the field of thermoacoustics, and builds upon the PI’s scientific expertise in combustion and acoustics and on his technological know-how."; "2019-06-26"; "European Research Council (ERC)"; "2024-08-31"; "ERC Consolidator Grant"; "2020-11-28"; "2019-09-01"; "2585170.0". a ; "Societal challenges | Health, demographic change and well-being | Active ageing and self-management of health"; "CORDA - COmmon Research DAta Warehouse - Horizon 2020"; "Supporting the Recognition of the Silver Economy in Europe in the Digital Era"; "ROBINSON, Simon"; "EUR"; "CSA"; ; ; ; ; ; ; ; ; ; "H2020-SC1-2016-CNECT"; "SEED"; "0"; "H2020-EU.3.1.4."; "997694.0"; "Societal Challenges"; "SEED is designed to ensure the successful launching of a highly visible and sustainable European-level award scheme rewarding innovative solutions that demonstrate a significant impact on the quality of life of the ageing population. The new award scheme will rely upon a carefully prepared conceptual and operational approach. A positive narrative will be developed suitable to effectively mobilise a wide range of stake holders across Europe. An appropriate organisational and technical infrastructure will be developed and set up, right from the beginning with a view to enabling a smooth hand-over by the SEED consortium to the party supposed to sustain the award scheme after the ending of the EU-funded project duration. It is envisaged that the award scheme will be maintained under the auspice of the recently launched European Covenant on Demographic Change. Sustainability and long-term visibility will also be ensured by the development of a viable sponsoring concept and business model. With the EU Covenant as a host and through the involvement of a great diversity of key networks and fora, this action will thrive towards a sustainable and multi-stakeholder driven movement at a European scale. The operational outreach into such a wide geographic area will not only be guaranteed by a carefully tailored communication and innovation strategy, but also by the active involvement of key players such as AGE, CORAL, AAL JP, all EIP AHA Action Groups, ECHAlliance, ASHOKA, ERRIN, DigitalEurope, EuroCarers, the Assembly of European Regions and highly committed regional/local governments. Through this unique partnership, the proposed action will have direct outreach to thousands of multiplier entities which together again reach out to millions of individuals across the EU. Towards the end of SEED, a high level award ceremony will be organised awarding winners of the 1st edition of the new award scheme."; "2018-03-12"; "Active ageing and self-management of health"; "Health"; "2018-09-30"; "Coordinated action to support the recognition of Silver Economy opportunities arising from demographic change"; "2020-11-28"; "2016-10-01"; "997694.0". a ; "Societal challenges"; "CORDA - COmmon Research DAta Warehouse - Horizon 2020"; "Magnesium and Aluminium Gas Injection Technology for High Pressure Die Casting"; "Op de Laak, Marcel"; "EUR"; "IA"; ; ; ; ; "H2020-EIC-FTI-2018-2020"; "MAGIT"; "0"; "H2020-EU.3."; "4133500.0"; "Societal Challenges"; "The MAGIT consortium comprises a German engineering company for product and process development (TiK), a Swiss aluminium die casting foundry (ALUWAG), a Belgium tool manufacturer (surtechno) (all SMEs) as well as a German Foundry Institute (Aalen University of Applied Sciences). Thus, the consortium has all necessary competences to achieve the objectives of the FTI project. The European automotive industry is faced with wide-ranging challenges in the common years. Especially electric mobility, lightweight design and intelligent use of materials is essential for current and future car development. In modern cars, many components are already produced in die casting, which is the most promising technology regarding cost-effective large-scale production. To extend the application possibilities of this technology, a new and disrupting process was developed, which enables the use of gas injection in aluminium or magnesium high pressure die casting and the production of components with hollow structures. Through this, significant cost savings can be achieved by the elimination of upstream and downstream manufacturing processes and weight can be reduced drastically by using lighter materials, but also new constructional possibilities for complex, hollow and thin-walled components with a load-adjusted design. By MAGIT, integrated fluid duct components can be realised. These can be used for cooling of power electronics and electric motors or temperature controlling of vehicle batteries. While the complex hollow components primarily address the European automotive industry, the new technology and the MAGIT device primarily addresses the European die casting industry for non-ferrous metals. By the innovative technology, the MAGIT consortium expects to generate additional cumulative turnover of 40 million € and an increase in staff headcount of 55 in 2024."; "2020-03-30"; "2023-02-28"; "Fast Track to Innovation (FTI)"; "2020-11-28"; "2020-03-01"; "2994400.0". a ; "Societal challenges | Secure, clean and efficient energy | A single, smart European electricity grid"; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; "CORDA - COmmon Research DAta Warehouse - Horizon 2020"; "Flexible smart metering for multiple energy vectors with active prosumers"; "MACII, Enrico"; "EUR"; "IA"; ; ; ; ; ; ; ; ; ; ; ; ; "H2020-LCE-2014-3"; "FLEXMETER"; "0"; "H2020-EU.3.3.4."; "3869610.0"; "Societal Challenges"; "The introduction of the electricity market, the widespread diffusion of distributed generation from renewable and non-programmable energy sources and the need for storage are quickly changing the problems that Transmission and Distribution system operators have to face in their activity and are requiring a “smarter” grid. A first step in this direction is the development and installation of a flexible smart metering architecture for multiple energy vectors. Up to now the smart meters that in some countries are being installed at the users are nearly only devoted to billing improvements. The new metering systems must go much further to provide their contribution to various objectives such as end-user affordability of electricity, energy and market efficiency improvement, CO2 emissions and pollutants reduction. In the FLEXMETER project a flexible, multi-utility, multi-service metering architecture will be designed and deployed in two demonstrators. Simple off-the-shelf meters will be placed at the users for electric, thermal and gas metering; they will communicate with a building concentrator, where the “smartness” of the metering system will reside. A central cloud system will collect data from the building concentrators and from MV/LV substation meters. Data collection, fusion and mining algorithms will be adopted. The proposed architecture will allow for innovative services for the prosumers (e.g. analysis of the energy consumption), for the Distribution System Operators (DSOs) (e.g. fault detection, network balancing and storage integration) and for the retail market. Also demand side management devices could be plugged into the system. In the FLEXMETER project two pilot applications in two different countries (Italy and Sweden), on real systems, with the involvement of the local DSOs and volunteer prosumers will be demonstrated. The results on the demonstrators will then be scaled up to the size of the cities in order to evaluate the advantages on a real scale."; "2018-03-12"; "A single, smart European electricity grid"; "Energy"; "2017-12-31"; "Distribution grid and retail market"; "2020-11-28"; "2015-01-01"; "3197790.0". a ; "Societal challenges | Secure societies - Protecting freedom and security of Europe and its citizens | Increase Europe's resilience to crises and disasters"; "CORDA - COmmon Research DAta Warehouse - Horizon 2020"; "Strengthening links between technologies and society for european disaster resilience"; "BOERSMA, Kees"; "EUR"; "RIA"; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; "H2020-SU-SEC-2019"; "LINKS"; "0"; "H2020-EU.3.7.5."; "5151780.0"; "Societal Challenges"; "In recent years, social media and crowdsourcing (SMCS) have been integrated into crisis management for improved information gathering and collaboration across European communities. The effectiveness of SMCS on European disaster resilience, however, remains unclear owing to the diversity among disaster risk perception and vulnerability LINKS sets out to understand and assess the effects of social media and crowd-sourcing (SMCS) on European disaster resilience. LINKS will develop a framework which can be used to understand, measure and govern SMCS for disasters, taking into account the diversity among disaster risk perception and vulnerability (DRPV), disaster management processes (DMP) and applied disaster community technologies (DCT) across European communities. The LINKS Framework consists of scientific methods, practical tools, and guidelines addressing researchers, practitioners and policy makers. The Framework will be developed and evaluated through five practitioner-driven European cases, representing different disaster scenarios (earthquake, flood, industrial, terror, drought), cutting across disaster management phases and diverse socioeconomic and cultural settings in four countries (Italy, Germany, Denmark, Netherlands). Furthermore, LINKS sets out to create a community of stakeholders, the LINKS Community, which brings together first-responders, public authorities, civil society organizations, business communities, citizens and researchers across Europe dedicated to improving European disaster resilience through the use of SMCS. The execution and success of the project relies on multiple levels of stakeholder engagement and knowledge exchange within the LINKS Community, facilitated online through the LINKS Community Center and in person through the LINKS Community Workshops. Overall, LINKS will provide sustainable, advanced learning on SMCS in disasters, in order to strengthen links between technologies and society for improved European disaster resilience."; "2020-05-16"; "Increase Europe's resilience to crises and disasters"; "Secure societies"; "2023-11-30"; "Human factors, and social, societal, and organisational aspects for disaster-resilient societies"; "2020-11-28"; "2020-06-01"; "5151780.0". a ; "Excellent science | Marie Skłodowska-Curie Actions | Nurturing excellence by means of cross-border and cross-sector mobility"; ; ; ; ; ; "CORDA - COmmon Research DAta Warehouse - Horizon 2020"; "Patterns and management of ethnic relations in the Western Balkans and the Baltic States"; "BERG, Eiki"; "EUR"; "MSCA-IF-EF-ST"; ; "H2020-MSCA-IF-2016"; "MERWBKBS"; "0"; "H2020-EU.1.3.2."; "136583.0"; "Excellent Science"; "‘Patterns and management of ethnic relations in the Western Balkans and the Baltic States’ This study will compare the management of ethnic relations in two Western Balkan states (Serbia and Croatia) with the management of ethnic relations in two Baltic republics (Latvia and Estonia). It will concentrate on: (a) the legal and institutional infrastructures on minority rights; (b) the impact of domestic and external actors on the management of ethnic relations. This research is placed inside the framework of the EU’s enlargement. Latvia and Estonia have been EU member-states since 2004. Croatia joined the EU in 2013 whereas accession negotiations with Serbia commenced in October 2011. By conducting research on two different post-Communist settings (two post-Yugoslav and two post-Soviet states) this comparative project will provide new insights in conflict resolution and the management of ethnic relations in the new and the aspiring EU member-states. Research questions: (a) How do the Western Balkan and Baltic models for managing ethnic relations compare to each other and to European standards? (b) How does the intersection between domestic and external actors impact on the management of ethnic relations in the Western Balkans and the Baltic States?"; "2018-03-12"; "MSCA Mobility"; "Marie-Sklodowska-Curie Actions"; "2019-04-30"; "Individual Fellowships"; "2020-11-28"; "2017-05-01"; "136583.0". a ; "Excellent science | European Research Council (ERC)"; ; ; ; ; ; ; ; ; ; ; "CORDA - COmmon Research DAta Warehouse - Horizon 2020"; "Mechanisms of RNA-guided genome editing in eukaryotes"; "NOWACKI, Mariusz"; "EUR"; "ERC-COG"; ; "ERC-2015-CoG"; "G-EDIT"; "0"; "H2020-EU.1.1."; "1953000.0"; "Excellent Science"; "The goal of this project is to contribute to our understanding of RNA-mediated epigenetic mechanisms of genome regulation in eukaryotes. Ciliated protozoa offer a fantastic opportunity to investigate the complex process of trans-generational programming of chromosomal rearrangements, which is thought to serve as a form of immune defense against invasive DNA. Developmental processes in ciliates include extensive rearrangements of the germline DNA, including elimination of transposons and the precise excision of numerous single-copy elements derived from transposons. This process is considered to be maternally controlled because the maternal genome provides essential information in the form of RNA that determines the offspring's genome content and organization. This programmed DNA subtraction, the so-called ‘RNA scanning’ process, is mediated by trans-generational comparison between the germline and the maternal somatic genome. One of the most intriguing questions is how a complex population of small RNAs representing the entire germline genome can be compared to the entire rearranged maternal genome, resulting in the efficient selection of germline-specific RNAs, which are able to target DNA deletions in the developing genome. All this occurs in a very short time and involves a massively coordinated transport of all the components between three types of nuclei. This project focuses on characterizing the molecular machinery that can orchestrate the massive genome rearrangements in ciliates through nucleic acids and protein interactions. It also addresses the question how RNA targets DNA cleavage at the right place. In addition, this project aims to investigate the role of RNA in guiding chromosomal rearrangements in other eukaryotic systems, particularly in human cancer cells where genome editing often occurs on a large scale. This work may be the first step in providing novel insights into the process of programmed DNA rearrangements in higher eukaryotes."; "2018-03-12"; "European Research Council (ERC)"; "2021-04-30"; "ERC Consolidator Grant"; "2020-11-28"; "2016-05-01"; "1953000.0". a ; "Euratom | Indirect actions"; "CORDA - COmmon Research DAta Warehouse - Horizon 2020"; "PAssive Systems: Simulating the Thermal-hydraulics with ExperimentaL Studies"; "Montout, Michael"; "EUR"; "IA"; ; ; ; ; ; ; ; ; ; ; ; "NFRP-2019-2020"; "PASTELS"; "0"; "H2020-Euratom-1."; "3801460.0"; "Euratom"; "PASTELS aims to significantly increase the knowledge within Europe of innovative passive systems, namely SACOs and CWCs, and the ability of several European system and CFD computational codes to be able to accurately model key phenomena such as natural circulation loops and condensation. This is very challenging due to their very specific properties, i.e. small driving forces working against high resistive forces which are specific to the concept of these technologies. Given the growing use of the SACO and CWC technologies in non-European NPPs, it is essential, especially with the foreseen future use of Small Medium Reactors (SMR) that the European nuclear community is able to adapt its current numerical tools to this promising technology. Extensive experimental testing (SET, CET and integral experiments) with representative operating conditions on semi-industrial full scale test facilities (PKL facility [DE] and PASI facility [FI]) will provide essential data to support the improvement of the numerical activities. Existing data from PERSEO and HERO-2 facilities will also be used. The numerical and experimental activities will be conducted in an integrated step-by-step approach. PASTELS will investigate improvements to models, novel methodologies for the coupling of system and CFD codes working at different scales. Additionally, important knowledge on the behaviour of the SACO and CWC will be captured through the observation of their behaviour during the test campaigns. Different and similar computational codes will be used by the partners in order to be able to benchmark and compare the different results obtained, understand the causes and propose strategies to improve them. All project results will feed into extensive methodology guidelines and a roadmap to achieving licensing and implementation of these innovative passive system technologies in future European NPPs."; "2020-05-30"; "Indirect actions"; "2024-02-29"; "Innovation for Generation II and III reactors"; "2020-11-28"; "2020-09-01"; "2993260.0". a ; "Industrial leadership | Leadership in enabling and industrial technologies | Information and Communication Technologies (ICT)"; "CORDA - COmmon Research DAta Warehouse - Horizon 2020"; "Virtual Optics - A software revolution in the optical industry"; "STAUDIGL, Luitpold"; "EUR"; "SME-1"; ; "H2020-SMEINST-1-2015"; "Virtual Optics"; "0"; "H2020-EU.2.1.1."; "71429.0"; "Industrial Leadership"; "Intelligent Imaging Solutions (IIS) is currently the worldwide technical leader in correcting optical aberrations by means of blind deconvolution. The unique approach of IIS is to determine optical aberrations from the image itself, accurately describe them mathematically and then reverse them through deconvolution. As a result, a dramatic increase in image quality can be achieved through the use of this software. IIS challenges the paradigm that image formation is only an optical task. The goal of IIS is to shift image formation to a combination of optical and software tasks. IIS wants to explore the possibilities in the aerial-camera-systems market which has a size of about 70 million EUR in net revenue and an operating margin of 20 percent. In this market, it is very difficult to improve image quality through classical optical design and manufacturing for cost reasons. Our approach is well-suited to this market as the optical systems are very expensive; whereas, computation power is cheap and readily available. In order to provide quality service to this market, additional investment aimed at significantly speeding up the technology is required. We expect to conclude the feasibility analysis by March 2016 and have a marketable solution shortly after that. We expect to team up with one of the leading manufacturers of aerial-camera systems or, alternatively, to provide a software solution directly to aerial-imaging companies seamlessly integrating into their workflow. Licensing fees are expected to be >150,000 EUR per year. Revenue from selling the software directly is estimated at around 750,000 EUR per year after three years as SaaS. We expect an IRR between 88–110 percent, a payback period between 12–17 months (upon release) and a ROI of 300–600 percent within a 48-month time frame—starting today and taking development and M&S costs into account."; "2018-03-12"; "Information and Communication Technologies"; "Leadership in enabling and industrial technologies (LEIT)"; "2016-04-30"; "Open Disruptive Innovation Scheme (implemented through the SME instrument)"; "2020-11-28"; "2015-09-01"; "50000.0". a ; "Excellent science | European Research Council (ERC)"; "CORDA - COmmon Research DAta Warehouse - Horizon 2020"; "dataFlow: A Data-driven Fluid Flow Solving Platform"; "THUEREY, Nils"; "EUR"; "ERC-POC"; ; "ERC-2018-PoC"; "dataFlow"; "0"; "H2020-EU.1.1."; "149500.0"; "Excellent Science"; "With the recent breakthrough of deep learning methods, we currenty see the advent of employing this methodology in the context of physical simulations. Such simulations are widely used in numerous industrial fields, starting from car and airplane manufacturers, over computer graphics and animations to medical blood flow simulations. The market for computer simulations is currently exceeding 15 billion USD world wide, with rising trends, and 3 billion spent in Europe alone. A significant fraction of these simulations focuses purely on solving various forms of the Navier-Stokes equations. While right now virtually all of these simulations use traditional solvers, we estimate than only a few years from now there will be a significant fraction of deep learning powered solvers. Thus, we are at the right point in time to lay the foundations for commercializing the technology of deep learning for fluid simulations. The goal of this PoC project is to develop a first commercial flow solver based on deep learning that can predict fluid flow solutions almost instantly using a pre-trained model. This project will enable the team of Prof. Thuerey to mature the algorithms developed as part of the ERC Starting Grant realflow, and turn them into the basis of a marketable product. The initial models will be thoroughly tested and validated, in order to satisfy industrial requirements for reliability and accuracy. In addition, this PoC aims for establishing a platform for flow data collection, interface standards, and trained models. This platform will be developed in conjunction to the deep-learning powered flow solving application, and provide research connections and publicity in parallel to it."; "2019-06-26"; "European Research Council (ERC)"; "2020-11-30"; "ERC Proof of Concept Grant"; "2020-11-28"; "2019-06-01"; "149500.0". a ; "Excellent science | Marie Skłodowska-Curie Actions | Nurturing excellence by means of cross-border and cross-sector mobility"; "CORDA - COmmon Research DAta Warehouse - Horizon 2020"; "RNAfate- revealing regulation of cellular “noise”."; "MORILLON, Antonin"; "EUR"; "MSCA-IF-EF-ST"; ; "H2020-MSCA-IF-2017"; "RNAfate"; "0"; "H2020-EU.1.3.2."; "173076.0"; "Excellent Science"; "RNA is an essential element in the flow of genetic information in the cell. Recent development of genome-wide techniques reveal multiple novel RNA transcripts, mostly non-coding (nc) for protein. Their significance for the cell is still poorly understood and at first they were considered as “noise”. During the recent decade research has revealed growing evidence for the importance of ncRNAs in cell development and disease. Further elaboration of their functions remains a pressing need in the field. To address this gap in knowledge we will focus on clarifying their regulation. One of key processes modulating levels of RNA in the cell is degradation. Xrn1 is a highly conserved 5’-3’ exoribonuclease that plays an important role in RNA decay. At the Institut Curie the Morillon’s group has discovered that a class of long non-coding (lnc)RNAs is highly sensitive to Xrn1-decay in yeast. The XRN1 sequence is well-conserved from yeast to human, but very little is known about human (h)Xrn1 targets other than mRNAs. Recent studies have revealed involvement of human lncRNAs in cancerogenesis or viral infection. Moreover, studies of Hepatitis C virus (HCV) have shown that viral infection change ncRNA levels. Others have reported that viral structured (sf)RNA can inhibit hXrn1. But how this sfRNA affect ncRNA-om was not yet determined. Importantly, Xrn1 can localize to cytoplasmic foci called P-bodies which are dynamic reservoirs of multiple RNAs and proteins involved in processes such RNA silencing or RNA decay. It has been demonstrated that P-bodies are altered in multiple human diseases and upon viral infection. There are three objectives for this project: 1) identifying novel members of the hXrn1-sensitive coding and noncoding transcriptome, 2) understanding, on a genome-wide scale, how the impairment of hXrn1 by viral sfRNA can change ncRNA stability, as well as their potential role in infection 3) defining the effect of hXrn1 impairment on P-body formation and composition."; "2018-04-21"; "MSCA Mobility"; "Marie-Sklodowska-Curie Actions"; "2021-08-31"; "Individual Fellowships"; "2020-11-28"; "2019-09-01"; "173076.0". a ; "Excellent science | Marie Skłodowska-Curie Actions | Nurturing excellence by means of cross-border and cross-sector mobility"; ; "CORDA - COmmon Research DAta Warehouse - Horizon 2020"; "Underspecification in spoken and written discourse: interpretation, compensation and cognitive implications"; "PICKERING, Martin"; "EUR"; "MSCA-IF-EF-ST"; ; "H2020-MSCA-IF-2017"; "Selfish discourse"; "0"; "H2020-EU.1.3.2."; "195455.0"; "Excellent Science"; "This research project focuses on underspecification, i.e. the imprecise use of words to express meanings which are not fully encoded in the semantics of the words themselves but which rely on common ground and other linguistic cues to be interpreted. I address in particular how underspecification explains the variable use of three French discourse markers and their English equivalents, namely et / and, mais / but and donc / so. This project seeks to establish the contextual and cognitive constraints to the production and interpretation of underspecified discourse markers by (i) analyzing their distribution and cooccurrence patterns in spoken, written and computer-mediated English and French and (ii) experimentally assessing their impact on discourse processing. This research thus combines corpus-based and experimental methods, as advocated by cognitivists. According to the selfish hypothesis, underspecification is a failure of recipient design and is thus expected to be more frequent in unplanned speech and computer-mediated writing, where speakers/writers are under higher cognitive pressure than in planned speech/writing. Furthermore, this project intends to show that register-sensitive patterns of co-occurrence constitute compensatory strategies designed to minimize the potentially detrimental effect of underspecification in processing complexity. Register and cooccurrence patterns are thus considered as windows onto underlying cognitive mechanisms of interpretation. SELFISH DISCOURSE will elucidate the relationship between a discourse marker and its co(n)text, teasing out their respective semantic-pragmatic contributions to the construal of senses and coming to terms with the theoretical overlap between polysemy, multifunctionality and underspecification. By combining corpus-based and experimental methods, this project contributes to a growing trend of linguistic research and fills a gap on the cross-modal study of underspecified discourse markers."; "2018-03-12"; "MSCA Mobility"; "Marie-Sklodowska-Curie Actions"; "2021-01-31"; "Individual Fellowships"; "2020-11-28"; "2019-02-01"; "195455.0". a ; "Societal challenges"; ; "CORDA - COmmon Research DAta Warehouse - Horizon 2020"; "Continuous hazardous water Pollutants sensing in the environment"; "KRANGNES, Lars"; "EUR"; "IA"; ; ; ; "H2020-EIC-FTI-2018-2020"; "CoPs"; "0"; "H2020-EU.3."; "2791430.0"; "Societal Challenges"; "CoPs combines the expertise of the 3 industry partners – ground-breaking electrochemical sensors developed by IPM, miniaturised electronics customised by PAL and CAU’s geo-monitoring hardware and software – and is expected to bring economic, social and environmental impacts, including towards achieving UN SDGs and EU policy. Pesticide and nitrate pollution in fresh waters pose a significant risk to public health and the environment. Exposure to pesticides can lead to several cancer types or Parkinson’s disease, while nitrate can result in “Blue Baby Syndrome” and cause eutrophication. According to latest estimates, getting sick from drinking tap water in Europe had a societal cost of €220 million. Meanwhile, inefficient water monitoring based on sampling and lab analyses does not provide early alerts. Water suppliers need to meet EU monitoring requirements and react instantly with contamination treatment protocols, protect water supplies and avoid economic losses through shutdowns. Our innovative solution rapidly detects specific water pollutants and transmit real-time data on contaminant levels and movements in natural water systems before they could reach water infrastructures and consumers. It saves both time and costs (by at least 40%), it vastly improves data quality and quantity, and it provides a data analysis and hazardous pollutants alert service to monitoring agencies. Our goal is to mature, scale-up and demonstrate the production of the CoPs sensor platform for continuous in-situ water monitoring, targeting water suppliers as initial clients, and with the potential to create new markets within the agriculture and private well owner segments. A successful CoPs project will allow us to create measurable impacts on our companies, quantified as accumulated revenue of €217m in five years (2021-2025), equal to accumulated operating profit of €86.05m, creating 101 full time employments in our value chain, and generating €21.83m in reduced costs for our end-users"; "2018-08-18"; "2021-08-31"; "Fast Track to Innovation (FTI)"; "2020-11-28"; "2018-09-01"; "1954000.0". a ; "SFRH/2011"; "SFRH/BPD/78198/2011"; "0"; "0.0"; "FCT - Fundação para a Ciência e a Tecnologia"; "SISTEMAS URBANÍSTICOS PORTUGUESES DE MATRIZ CONVENTUAL"; "2016-03-14"; "2018-08-07"; "UNKNOWN"; "2012-03-01"; "0.0". a ; ; ; "FCT - Fundação para a Ciência e a Tecnologia"; "R&D.COM - Local R&D.COMpetencies in global value chains"; "Sociology"; "UNKNOWN"; "POCI/2004"; "POCI/SOC/60092/2004"; "0"; "0.0"; "2015-08-24"; "2008-06-30"; "2018-08-07"; "2005-07-24"; "0.0". a ; "SFRH/2012"; "SFRH/BD/84967/2012"; "0"; "0.0"; ; "FCT - Fundação para a Ciência e a Tecnologia"; "VARIEDADES CARÁCTERES"; "2016-03-14"; "2018-08-07"; "UNKNOWN"; "2013-11-01"; "0.0". a ; ; ; ; "FCT - Fundação para a Ciência e a Tecnologia"; "S-Glutathionylation in Parkinson´s Disease."; "Neurosciences, Ageing and Degenerative Diseases - Organs and Systems Degeneration"; "UNKNOWN"; "PTDC/2012"; "PTDC/NEU-OSD/0502/2012"; "0"; "0.0"; "2015-08-24"; "2015-11-30"; "2018-08-07"; "2013-06-01"; "0.0". a ; "SFRH/2006"; "SFRH/BD/29154/2006"; "0"; "0.0"; "FCT - Fundação para a Ciência e a Tecnologia"; "COMPLEXOS DE ELEMENTOS EMISSORES DE RADIAÇÃO GAMA E DE ELECTRÕES AUGER PARA DIAGNÓSTICO E/OU TERAPIA DO CANCRO"; "2016-03-14"; "2018-08-07"; "UNKNOWN"; "2007-01-01"; "0.0". a ; ; ; "FCT - Fundação para a Ciência e a Tecnologia"; "Characterisation and applications of a novel hemangioblast-specific transcriptional enhancer"; "Health Sciences - Molecular Medicine"; "UNKNOWN"; "POCI/2004"; "POCI/SAU-MMO/59725/2004"; "0"; "0.0"; "2015-08-24"; "2007-12-31"; "2018-08-07"; "2005-10-01"; "0.0". a ; "SFRH/2013"; "SFRH/BPD/95446/2013"; "0"; "0.0"; "FCT - Fundação para a Ciência e a Tecnologia"; "LAYER-BY-LAYER COMPARTMENTALIZED STRUCTURES AS CUSTOMIZABLE AND MULTIFUNCTIONAL MICROREACTORS"; "2016-03-14"; "2018-08-07"; "UNKNOWN"; "2014-04-01"; "0.0". a ; ; "FCT - Fundação para a Ciência e a Tecnologia"; "A holistic approach to assess phenotype-dependent variations in chemical composition of softwoods on the tree-ring level"; "Agricultural and Forestry Sciences - Bio-based Product Technology"; "UNKNOWN"; "RECI/2012"; "RECI/AGR-TEC/0493/2012"; "0"; "0.0"; "2015-08-24"; "2016-04-30"; "2018-08-07"; "2013-05-01"; "0.0". a ; "0"; "0.0"; "Fonds zur Förderung der Wissenschaftlichen Forschung"; "Cultural History of the Western Himalaya"; "2020-07-15"; "2006-12-31"; "Deborah KLIMBURG-SALTER"; "2020-12-09"; "EUR"; "2001-06-01"; ; "631054.0". a ; "Fonds zur Förderung der Wissenschaftlichen Forschung"; "UN Tort Law for Peacekeeping Missions"; "International Organizations, United Nations, Peacekeeping, Tort, Third Party Claims, Claims Settlement Practice"; "Kirsten SCHMALENBACH"; "EUR"; ; "0"; "0.0"; "2020-07-15"; "2023-12-31"; "2020-12-09"; "2021-01-01"; "370776.0". a ; "Fonds zur Förderung der Wissenschaftlichen Forschung"; "Optimized topical glucocorticoid-therapy of the inner ear"; "inner ear, hearing loss, glucocorticoids, topical therapy, cochlear implant, selective glucocorticoid receptor agonists"; "Christoph ARNOLDNER"; "EUR"; ; "0"; "0.0"; "2020-07-15"; "2017-01-31"; "2020-12-09"; "2012-02-01"; "188748.0". a ; "Fonds zur Förderung der Wissenschaftlichen Forschung"; "Design of a high-speed packet-switched OTDM network"; "Photonic Networks, OTDM, MAC protocols, Programmable Logic Design (PD), PMD compensation, OTDM/WDM interface"; "Harmen R. 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CHARAKTERISIERUNG V. 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"2016-03-10"; "1979-06-30"; "Atkinson, George"; "2018-08-07"; "Standard Grant"; "1977-01-15"; ; "0.0". a ; "NSF - National Science Foundation"; "International Research Fellowship Program: Guided Wave Interaction with Cantor Fractal Multilayers"; "Johnson, Shikik"; "Fellowship"; ; "0"; "0.0"; "2016-03-10"; "2008-11-30"; "Other Applications NEC"; "2018-08-07"; "2006-06-01"; "0.0". a ; "0"; "0.0"; "NSF - National Science Foundation"; "PRIMARY PHOTOCHEMICAL AND ELECTRON-TRANSPORT REACTIONS IN PHOTOSYNTHESIS"; "2016-03-10"; "1973-01-01"; "2018-08-07"; "1971-01-01"; ; "0.0". a ; "0"; "0.0"; "NSF - National Science Foundation"; "Quantitative Aspects of Secondary Production in Estuarine Fish Populations"; "2016-03-10"; "1962-01-01"; "2018-08-07"; "1961-01-01"; ; "0.0". a ; "NSF - National Science Foundation"; "Electrochemical Studies of Transition Metal Silicates and Oxides"; "Arculus, Richard"; "Continuing grant"; ; "0"; "0.0"; "2016-03-10"; "1989-05-31"; "Geological Sciences"; "2018-08-07"; "1985-06-01"; "0.0". a ; "NSF - National Science Foundation"; "Equipment for Computer Research"; "Stockman, George"; "Standard Grant"; ; "0"; "0.0"; "2016-03-10"; "1987-05-31"; "Other Applications NEC"; "2018-08-07"; "1985-12-01"; "0.0". a ; "NSF - National Science Foundation"; "CAREER: Benthic Boundary Mixing and Dissolved Oxygen Transfer at the Sediment Water Interface in a Stratified Lake"; "Hondzo, Miki"; "Continuing grant"; ; "0"; "0.0"; "2016-03-10"; "2002-04-30"; "Industrial Technology"; "2018-08-07"; "1999-08-01"; "0.0". a ; ; ; ; "NSF - National Science Foundation"; "Fundamental Study of Processes Associated with Stable Trapping and Potential Leakage of Sequestrated Carbon Dioxide in Deep Geologic Formations"; "Illangasekare, Tissa"; "Continuing grant"; ; "0"; "0.0"; "2016-03-10"; "2014-12-31"; "2018-08-07"; "2011-01-01"; "0.0". a ; "NSF - National Science Foundation"; "Bridge Replacement Decks of Steel"; "Touran, Ali"; "Standard Grant"; ; "0"; "0.0"; "2016-03-10"; "1988-01-31"; "Engineering-Civil"; "2018-08-07"; "1986-08-15"; "0.0". a ; "0"; "0.0"; "NSF - National Science Foundation"; "MRI: Acquisition of Instrumentation for Compound-Specific Stable Isotope Analysis at the University of New Mexico"; "2016-03-10"; "2016-07-31"; "Sharp, Zachary"; "2018-08-07"; "Standard Grant"; "2014-08-15"; ; "0.0". a ; ; "NSF - National Science Foundation"; "AF: Medium: Collaborative Research: Information Compression in Algorithm Design and Statistical Physics"; "Achlioptas, Dimitris"; "Standard Grant"; ; "0"; "0.0"; "2016-03-10"; "2018-05-31"; "2018-08-07"; "2015-06-15"; "0.0". a ; "NSF - National Science Foundation"; "RUI: Water Vapor and Lightning Effects on D-Region Radio Wave Propagation"; "Moser, James"; "Standard Grant"; ; "0"; "0.0"; "2016-03-10"; "1989-02-28"; "Atmospheric Sciences"; "2018-08-07"; "1986-09-01"; "0.0". a ; "0"; "0.0"; "NSF - National Science Foundation"; "Using Techniques of Molecular Biology to Improve Skills and Attitudes of Students in Biological Science Courses"; 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"2016-03-10"; "1980-03-31"; "Nibler, Joseph"; "2018-08-07"; "Standard Grant"; "1979-04-15"; ; "0.0". a ; "NSF - National Science Foundation"; "Homotopy Theory Program at the University of Western Ontario"; "Goerss, Paul"; "Standard Grant"; ; "0"; "0.0"; "2016-03-10"; "2004-06-30"; "Other Applications NEC"; "2018-08-07"; "2003-07-01"; "0.0". a ; "0"; "0.0"; "NSF - National Science Foundation"; "DISSERTATION RESEARCH: Linking microbial community assembly and elemental cycles in a natural micro-ecosystem"; "2016-03-10"; "2016-05-31"; "Sousa, Wayne"; "2018-08-07"; "Standard Grant"; "2014-06-01"; ; "0.0". a ; "NSF - National Science Foundation"; "Impacts of Mesoscale Processes on Biogeochemical Fluxes in the North Atlantic: Basin-Scale Eddy-Resolving Simulations"; "McGillicuddy, Dennis"; "Standard Grant"; ; "0"; "0.0"; "2016-03-10"; "2006-02-28"; "Oceanography"; "2018-08-07"; "2001-03-15"; "0.0". a ; "NSF - National Science Foundation"; "Cell Interactions and Cell Fate Specification"; "Ettensohn, Charles"; "Continuing grant"; ; "0"; "0.0"; "2016-03-10"; "1998-08-31"; "Life Science Biological"; "2018-08-07"; "1994-09-01"; "0.0". a ; "NSF - National Science Foundation"; "Sodium Transport in Renal Tubules"; "Stoner, Larry"; "Continuing grant"; ; "0"; "0.0"; "2016-03-10"; "1999-06-30"; "Life Science Biological"; "2018-08-07"; "1995-07-15"; "0.0". a ; "0"; "0.0"; "NSF - National Science Foundation"; "PURCHASE OF AN ELECTRON SPECTROMETER"; "2016-03-10"; "1974-01-01"; "2018-08-07"; "1973-01-01"; ; "0.0". a ; "0"; "0.0"; "NSF - National Science Foundation"; "Dynamics and Mechanism in Organic Chemistry"; "2016-03-10"; "1996-12-31"; "Doering, William"; "2018-08-07"; "Continuing grant"; "1994-07-15"; ; "0.0". a ; "NSF - National Science Foundation"; "Thin Flim Squids of High TC Materials"; "Vittoria, Carmine"; "Continuing grant"; ; "0"; "0.0"; "2016-03-10"; "1994-08-31"; "Engineering-Electrical"; "2018-08-07"; "1991-03-01"; "0.0". a ; "0"; "0.0"; "NSF - National Science Foundation"; "RESEARCH INITIATION-URBAN GOODS MOVEMENT DEMAND MODELING"; 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"2016-03-10"; "1972-01-01"; "2018-08-07"; "1970-01-01"; ; "0.0". a ; "0"; "0.0"; "NSF - National Science Foundation"; "Collaborative Research: Investigating Secondary Organic Aerosol (SOA) Formation in Central Los Angeles for Research at the Nexus of Air Quality and Climate Change (CalNex 2010)"; "2016-03-10"; "2012-08-31"; "Weber, Rodney"; "2018-08-07"; "Standard Grant"; "2009-09-01"; ; "0.0". a ; ; "NSF - National Science Foundation"; "Exact Sampling via Markov Chains"; "Fill, James"; "Standard Grant"; ; "0"; "0.0"; "2016-03-10"; "1998-06-30"; "Mathematics"; "2018-08-07"; "1996-07-01"; "0.0". a ; "NSF - National Science Foundation"; "Adaptive Change and Continuity in the Lake Baikal Region"; "Ezzo, Joseph"; "Standard Grant"; ; "0"; "0.0"; "2016-03-10"; "2000-07-31"; "Other Applications NEC"; "2018-08-07"; "1998-08-01"; "0.0". a ; "0"; "0.0"; "NSF - National Science Foundation"; "Methods of Mathematical Finance"; "2016-03-10"; "2016-04-30"; "Kramkov, Dmitry"; "2018-08-07"; "Standard Grant"; 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"1966-10-01"; "2018-08-07"; "1966-01-01"; ; "0.0". a ; "0"; "0.0"; "NSF - National Science Foundation"; "SBIR Phase I: Functionalized Graphene-Based Biosensors"; "2016-03-11"; "2012-08-31"; "Punckt, Christian"; "2018-08-07"; "Standard Grant"; "2012-01-01"; ; "0.0". a ; "NSF - National Science Foundation"; "Development of Bioerodible Polymer Matrices for Osteoblast Growth and Maturation"; "Laurencin, Cato"; "Continuing grant"; ; "0"; "0.0"; "2016-03-11"; "1995-12-31"; "Engineering NEC"; "2018-08-07"; "1993-07-01"; "0.0". a ; "NSF - National Science Foundation"; "Collaborative Research: Self-Propagating Eddies in Realistic Basins"; "Dewar, William"; "Standard Grant"; ; "0"; "0.0"; "2016-03-11"; "2006-08-31"; "Oceanography"; "2018-08-07"; "2002-09-15"; "0.0". a ; ; "NSF - National Science Foundation"; "Collaborative Research: SHINE--Magnetic Energy Release During Solar Eruptions - From Large to Small Scales"; "Chen, Bin"; "Standard Grant"; ; "0"; "0.0"; "2019-09-12"; "2020-07-31"; "2019-09-12"; 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"Propagation of corrugated flames in the flamelet regime"; "2016-03-11"; "2015-03-31"; "Matalon, Moshe"; "2018-08-07"; "Standard Grant"; "2011-04-01"; ; "0.0". a ; "0"; "0.0"; "NSF - National Science Foundation"; "DOCTORAL DISSERTATION RESEARCH IN PHYSIOLOGICAL CORRELATES TO HIBERNATION IN `SCAPHIOPUS'"; "2016-03-11"; "1973-01-01"; "2018-08-07"; "1971-01-01"; ; "0.0". a ; "NSF - National Science Foundation"; "Research Initiation: Environmental Factors Affecting Phosphorus Release/Uptake of Acinetobacter Species"; "Hao, Oliver"; "Standard Grant"; ; "0"; "0.0"; "2016-03-11"; "1986-02-28"; "Engineering-Civil"; "2018-08-07"; "1983-09-01"; "0.0". a ; "NSF - National Science Foundation"; "Workshop on Eco-Cultural Niche Modeling: Hominin Dispersal and Adaptation to High Latitudes"; "Dibble, Harold"; "Standard Grant"; ; "0"; "0.0"; "2016-03-11"; "2006-06-30"; "Polar Programs-Related"; "2018-08-07"; "2005-07-15"; "0.0". a ; "0"; "0.0"; "NSF - National Science Foundation"; "A Synopsis of North American Desmidieae"; "2016-03-11"; "1972-01-01"; "2018-08-07"; "1970-01-01"; ; "0.0". a ; "0"; "0.0"; "NSF - National Science Foundation"; "The Activation Approach: A Comprehensive Method and Toolkit for Evaluating the Impact of Science Learning Experiences Across Environments"; "2016-03-11"; "2017-08-31"; "Dorph, Rena"; "2018-08-07"; "Standard Grant"; "2013-09-01"; ; "0.0". a ; "0"; "0.0"; "NSF - National Science Foundation"; "The Vibrational Dynamics of Bimolecular Reactions in Gases and Liquids"; "2016-03-11"; "2009-06-30"; "Crim, F. Fleming"; "2018-08-07"; "Continuing grant"; "2006-07-01"; ; "0.0". a ; "NSF - National Science Foundation"; "Quaternary Environments and Plant Geography of Chile"; "Heusser, Calvin"; "Continuing grant"; ; "0"; "0.0"; "2016-03-11"; "1986-04-30"; "Atmospheric Sciences"; "2018-08-07"; "1983-11-15"; "0.0". a ; "NSF - National Science Foundation"; "PRF: Cladistics and Genetic Distinctness of Protected and Extinct Members of the Coregoninae (Family Salmonidae) in North America"; "Shields, Barbara"; "Fellowship"; ; "0"; "0.0"; "2016-03-11"; "1994-04-30"; "Life Science Biological"; "2018-08-07"; "1991-10-15"; "0.0". a ; "0"; "0.0"; "NSF - National Science Foundation"; "Development of Real-Time Interference Mitigation and Instrumentation for Radio Astronomy"; "2016-03-11"; "2008-09-30"; "Fisher, James"; "2018-08-07"; "Cooperative Agreement"; "2004-09-01"; ; "0.0". a ; "NSF - National Science Foundation"; "NSF Young Investigator"; "Knittle, Elise"; "Continuing grant"; ; "0"; "0.0"; "2016-03-11"; "1998-09-30"; "Geological Sciences"; "2018-08-07"; "1992-09-15"; "0.0". a ; "0"; "0.0"; "NSF - National Science Foundation"; "II-NEW: Collaborative Research: COMET: A Web Infrastructure for Research and Experimentation in User Interactive Event Driven Testing"; "2016-03-11"; "2016-07-31"; "Cohen, Myra"; "2018-08-07"; "Continuing grant"; "2012-08-01"; ; "0.0". a ; "NSF - National Science Foundation"; "Instabilities and Phase Transitions in Light-Matter Interaction (Physics)"; "Singh, Surendra"; "Continuing grant"; ; "0"; "0.0"; "2016-03-11"; "1990-01-31"; "Physics"; "2018-08-07"; "1987-08-01"; "0.0". a ; "0"; "0.0"; "NSF - National Science Foundation"; "Mathematical Sciences: Undergraduate Research in Numerical Linear Algebra and Optimization"; "2016-03-11"; "1992-11-30"; "Edwards, Teresa"; "2018-08-07"; "Standard Grant"; "1991-06-01"; ; "0.0". a ; "0"; "0.0"; "NSF - National Science Foundation"; "Developing, Field-Testing, and Validating An Elementary Algebra Concept Inventory Database For Use In The College Context"; 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"2017-09-23"; "Humanities and Social Sciences;Sociology, social work, political sciences, media and communication studies, health"; "2008-07-31"; "Lalive d'Epinay Christian"; "2018-08-07"; "2005-01-01"; ; ; "0.0". a ; "0"; "0.0"; "SNSF - Swiss National Science Foundation"; "Lost in Transit? Fragmented Journeys of Young Migrants with no Chance of Admission in Europe"; "2017-09-23"; "Humanities and Social Sciences;Sociology, social work, political sciences, media and communication studies, health"; "2017-10-31"; "Wyss Anna"; "2018-08-07"; "2013-10-01"; ; ; "0.0". a ; "0"; "0.0"; "SNSF - Swiss National Science Foundation"; "Die dritte Dimension der Stadt"; "2017-09-22"; "Humanities and Social Sciences;Art studies, musicology, theatre and film studies, architecture"; "2016-07-31"; "Lampugnani Vittorio"; "2018-08-07"; "2016-05-01"; ; ; "0.0". a ; "0"; "0.0"; "SNSF - Swiss National Science Foundation"; "Behaviour emergence within artificial beings"; "2017-09-22"; "Mathematics, Natural- and Engineering Sciences;Engineering Sciences"; "1997-04-30"; "Nicoud Jean-Daniel"; "2018-08-07"; "1994-10-01"; ; "0.0". a ; "0"; "0.0"; "SNSF - Swiss National Science Foundation"; "Realstruktur dünner Aufdampfschichten auf Einkristallsubstraten und ihr Einfluss auf deren chemische Reaktivität."; "2017-09-22"; "Mathematics, Natural- and Engineering Sciences;Chemistry"; "1990-11-30"; "Safran György"; "2018-08-07"; "1990-11-01"; ; "0.0". a ; "0"; "0.0"; "SNSF - Swiss National Science Foundation"; "Knock-out mice for the calcium-binding protein parvalbumin; models for muscle and brain diseases"; "2017-09-23"; "Biology and Medicine;Basic Medical Sciences"; "2004-03-31"; "Celio Marco"; "2018-08-07"; "2000-04-01"; ; "0.0". a ; "0"; "0.0"; "SNSF - Swiss National Science Foundation"; "Datenschutz als Vermögensrecht"; "2020-08-26"; "Humanities and Social Sciences;Economics, law"; "2020-08-31"; "Schmidt Kirsten Johanna"; "2020-08-26"; "2020-03-01"; ; "0.0". a ; "0"; "0.0"; "SNSF - Swiss National Science Foundation"; "C13.0056: Treeline dynamics in the Swiss Alps: combining dendroecological reconstructions of relict treelines with projections from a forest succession model"; "2017-09-22"; "2017-01-31"; "Bigler Christof"; "2018-08-07"; "2017-01-01"; ; "0.0". a ; "0"; "0.0"; "SNSF - Swiss National Science Foundation"; "Geschichte Machen. Darstellungen der Vergangenheit und ihre Funktionen in Städten des deutschen Südwestens, 14. - 16. 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Magnetron Sputtering."; "2017-09-22"; "Mathematics, Natural- and Engineering Sciences;Physics"; "2002-08-22"; "Kim Sun Kyu"; "2018-08-07"; "2002-07-23"; ; "0.0". a ; "0"; "0.0"; "SNSF - Swiss National Science Foundation"; "Role of the pineal/retinae acidic 33 kDa phosphoprotein MEKA (phosducin) in signal transduction."; "2017-09-22"; "Biology and Medicine;Basic Medical Sciences"; "1991-12-31"; "Schaad Nicholas C."; "2018-08-07"; "1991-01-01"; ; "0.0". a ; "0"; "0.0"; "SNSF - Swiss National Science Foundation"; "Dendrohydrologische Rekonstruktion von langfristigen Wasserspiegelschwankungen des Lac Duparquet', Québec, Kanada"; "2017-09-22"; "Mathematics, Natural- and Engineering Sciences;Environmental Sciences"; "1998-09-30"; "Schweingruber Fritz"; "2018-08-07"; "1995-10-01"; ; ; ; "0.0". a ; ; "SNSF - Swiss National Science Foundation"; "Solving Computationally Hard Problems by Classifying the Hardness of Input Instances"; "Mathematics, Natural- and Engineering Sciences;Engineering Sciences"; "Hromkovic Juraj"; ; "0"; "0.0"; "2017-09-23"; "2013-10-31"; "2018-08-07"; "2010-11-01"; "0.0". a ; ; ; ; ; ; ; ; "SNSF - Swiss National Science Foundation"; "Integrative analysis of germline and somatic genetic variation in 2000 cancer patients"; "Biology and Medicine;Basic Biological Research"; "Waszak Sebastian"; ; "0"; "0.0"; "2017-09-22"; "2015-12-31"; "2018-08-07"; "2014-07-01"; "0.0". a ; "0"; "0.0"; "SNSF - Swiss National Science Foundation"; "Molecular mechanisms of alveolar cell death in hyperoxia-induced lung injury."; "2017-09-22"; "Biology and Medicine;Experimental Medicine"; "2005-09-30"; "Barazzone-Argiroffo Constance"; "2018-08-07"; "2002-10-01"; ; "0.0". a ; "0"; "0.0"; "SNSF - Swiss National Science Foundation"; "Die dynamischen Vorgänge bei der Um- und Ueberströmung drei- dimensionaler Gebirge durch eine stratifizierte hydrostatische Atmosphäre."; "2017-09-22"; "Mathematics, Natural- and Engineering Sciences;Environmental Sciences"; "1990-12-31"; "Schär Christoph"; "2018-08-07"; "1990-01-01"; ; "0.0". a ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; "SNSF - Swiss National Science Foundation"; "Embeddings in Higher Dimensions: Algorithms and Combinatorics"; "Mathematics, Natural- and Engineering Sciences"; "Wagner Ulrich"; ; ; ; "0"; "0.0"; "2017-09-22"; "2016-06-30"; "2018-08-07"; "2012-07-01"; "0.0". a ; "0"; "0.0"; "SNSF - Swiss National Science Foundation"; "Nuclide Production in the Solar System"; "2020-11-14"; "Mathematics, Natural- and Engineering Sciences"; "2023-09-30"; "Leya Ingo"; "2020-11-14"; "2020-10-01"; ; "0.0". a ; "0"; "0.0"; "SNSF - Swiss National Science Foundation"; "Arbeit am Beruf. Feminismus und Berufsberatung im 20. Jahrhundert"; "2019-06-14"; "Humanities and Social Sciences;Theology & religious studies, history, classical studies, archaeology, prehistory and early history"; "2019-04-30"; "Angehrn Céline"; "2019-06-14"; "2018-05-01"; ; "0.0". a ; "0"; "0.0"; "SNSF - Swiss National Science Foundation"; "Neue Einsichten in die Sonden-Proben-Wechselwirkung bei den Rastersondenmethoden"; "2017-09-22"; "Mathematics, Natural- and Engineering Sciences;Physics"; "2013-09-30"; "Meyer Ernst"; "2018-08-07"; "2011-10-01"; ; ; "0.0". a ; "0"; "0.0"; "SNSF - Swiss National Science Foundation"; "Modèlisation électromagnétique en géophysique"; "2017-09-23"; "Mathematics, Natural- and Engineering Sciences;Earth Sciences"; "1984-09-30"; "Fischer Gaston"; "2018-08-07"; "1983-10-01"; ; "0.0". a ; ; ; ; ; ; "SNSF - Swiss National Science Foundation"; "Seismic response and deformation of deep-seated rock slopes instabilities -predicting earthquake-induced deformation and the potential for catastrophic failure"; "Mathematics, Natural- and Engineering Sciences;Earth Sciences"; "Gischig Valentin"; ; "0"; "0.0"; "2017-09-22"; "2014-08-31"; "2018-08-07"; "2014-02-01"; "0.0". a ; "0"; "0.0"; "SNSF - Swiss National Science Foundation"; "How elites shape unequal democracies: Perceptions of redistribution in Brazil and South Africa"; "2020-08-26"; "Humanities and Social Sciences;Sociology, social work, political sciences, media and communication studies, health"; "2024-08-31"; "Moraes Dias da Silva Graziella"; "2020-08-26"; "2020-09-01"; ; "0.0". a ; "0"; "0.0"; "SNSF - Swiss National Science Foundation"; "Medical Review in the Disability Determination Process: An Evaluation of the Treating Physician Rule"; "2019-02-14"; "Humanities and Social Sciences;Economics, law"; "2020-09-30"; "Liebert Helge"; "2019-02-14"; "2019-02-01"; ; "0.0". a ; ; ; ; "SNSF - Swiss National Science Foundation"; "New challenges in mapping seismic waveforms into the Earth's mantle: anisotropy and mantle flow"; "Mathematics, Natural- and Engineering Sciences;Earth Sciences"; "Giardini Domenico"; ; "0"; "0.0"; "2017-09-23"; "2015-10-31"; "2018-08-07"; "2013-11-01"; "0.0". a ; "0"; "0.0"; "SNSF - Swiss National Science Foundation"; "Software Radio and Interference Cancellation"; "2017-09-22"; "Mathematics, Natural- and Engineering Sciences;Engineering Sciences"; "2003-12-31"; "Rimoldi Bixio"; "2018-08-07"; "1999-10-01"; ; "0.0". a ; "0"; "0.0"; "SNSF - Swiss National Science Foundation"; "Role of reactive oxygen species in the regulation of beta-1-integrin expression and function in cardiomyocytes (Score)"; "2017-09-22"; "Biology and Medicine;Basic Medical Sciences"; "2011-12-31"; "Kuster Gabriela"; "2018-08-07"; "2006-09-01"; ; "0.0". a ; "0"; "0.0"; "SNSF - Swiss National Science Foundation"; "Herstellung von Protoplasten der species Acremonium coenophialum und A. lolii. Fusion der Protoplasten intraspezifisch."; "2017-09-22"; "1990-11-13"; "Ferenczy Lajos"; "2018-08-07"; "1990-10-14"; ; "0.0". a ; "0"; "0.0"; "SNSF - Swiss National Science Foundation"; "Time-Resolved X-Ray Absorption Spectroscopy."; "2017-09-23"; "Mathematics, Natural- and Engineering Sciences;Physics"; "2000-11-29"; "van Mourik Frank"; "2018-08-07"; "2000-10-30"; ; "0.0". a ; "0"; "0.0"; "SNSF - Swiss National Science Foundation"; "Historische Grundlagenforschung im antiken Kleinasien: A. Nord- kleinasien in römischer Zeit - B. Corpus der Inschriften von Kaunos."; "2017-09-23"; "Humanities and Social Sciences;Theology & religious studies, history, classical studies, archaeology, prehistory and early history"; "1999-09-30"; "Marek Christian"; "2018-08-07"; "1996-06-01"; ; "0.0". a ; "0"; "0.0"; "SNSF - Swiss National Science Foundation"; "Impact des changements climatiques sur le comportement des systèmes aquifères souterrains"; "2017-09-23"; "Mathematics, Natural- and Engineering Sciences;Environmental Sciences"; "1995-12-31"; "Zwahlen François"; "2018-08-07"; "1992-07-01"; ; "0.0". a ; "0"; "0.0"; ; "Türkiye Bilimsel ve Teknolojik Araştırma Kurumu"; "Karbon Kısıtlı Çevrede Enerji Yatırım Planlaması Için Eniyileme Modellerinin Geliştirilmesi Ve Bu Modellerin Ekonomi Ve Stratejik Planlama Açısından Analizi"; "2017-11-02"; "2017-03-10"; "2018-08-07"; "2015-03-10"; "0.0". a ; "0"; "0.0"; ; "Türkiye Bilimsel ve Teknolojik Araştırma Kurumu"; "Vaskülojenik erektil disfonksiyonda resveratrolün oksidatif stres üzerine olan etkileri"; "2017-11-02"; "2014-03-04"; "2018-08-07"; "2011-03-10"; "0.0". a ; ; ; ; ; ; ; ; "UK Pubmed Central - Wellcome Trust"; "How can Universal Health Coverage benefit the poor? Examining the equity and pro-poorness of health financing reforms in Kenya."; "International Training Fellowship - Full"; "Dr Barasa, Edwine E"; "GBP"; "UNKNOWN"; ; ; "0"; "0.0"; "There is growing commitment by developing countries to achieve Universal Health Coverage (UHC). The goal of UHC is to ensure that everyone can use the health services they need without risk of financial ruin. There is however evidence that, if not well designed, these efforts tend to benefit the well-off while excluding the poor in society, resulting in highly inequitable health systems. Using multiple methods (cross-sectional survey, in-depth interviews, focused group discussions, document revi ew), the this research will explore how best UHC efforts in Kenya can be designed to offer financial risk protection for all while ensuring equity in access to needed services and the inclusion of the poor. Key questions that will be answered by the study include; what are the determinants of inequity in use of health services? How can the poor be identified and how can healthcare services be extended to reach them? How can the institutional design and organizational capacities of health fi nancing systems ensure equity and pro-poorness? What are the perceptions and experiences of the poor and the barriers they face in benefiting from HF mechanisms? Results will inform national and international UHC policy debates and the design of health policy reform."; "2016-12-22"; "2018-07-31"; "2020-12-08"; "2015-08-01"; "246214.0". a ; "UK Pubmed Central - Wellcome Trust"; "Development of Guidelines on Mental Health in the Workplace"; "Discretionary Award – Directorate"; "Dr van Ommeren, Mark M"; "GBP"; "UNKNOWN"; ; "0"; "0.0"; "Work is good for mental health but a negative working environment can lead to physical and mental health problems. Depression and anxiety have a significant economic impact; the estimated cost to the global economy is US$ 1 trillion per year in lost productivity. Harassment and bullying at work are commonly reported problems, and can have a substantial adverse impact on mental health. There are many effective actions that organizations can take to address mental health in the workplace; such actions may also benefit productivity. WHO will produce evidence-based guidelines on this and will seek to do this in collaboration with ILO."; "2019-12-17"; "2021-09-01"; "2020-12-08"; "2019-09-01"; "387458.0". a ; "UK Pubmed Central - Wellcome Trust"; "Provision of high-resolution proteomics to enhance forward and back translational research."; "Multi-User Equipment Grant"; "Professor Cullen, Peter PJ"; "GBP"; "UNKNOWN"; ; ; ; "0"; "0.0"; "A major health science focus across the University of Bristol is the facilitation of forward translation (molecular and physiological sciences generating knowledge about disease pathways, biomarkers and targets), and back-translation (insight from population health sciences informing molecular and physiological sciences). Each translational route increasingly relies on high-resolution proteomics. Funds are requested to assist in the purchase of an Orbitrap Fusion Tribrid Mass Spectrometer, wh ich combines quadrupole, Orbitrap, and linear ion trap mass analysers to provide an unprecedented depth of proteomic analysis. Unique Tribrid architecture and Dynamic Scan Management allow simultaneous precursor isolation, fragmentation, and data acquisition in both Orbitrap and ion trap mass analyzers, maximizing the through-put and amount of high-quality data acquired. Improved sensitivity, scan rate, and mass resolution significantly increase proteome coverage and enhance the ability to posit ively identify more low-abundance proteins, while the use of novel SPS MS3 technology provides un-paralleled accuracy of protein quantitation and identification when using isobaric mass tags. Overall, the instrument will: analyse the most challenging low-abundance or high-complexity samples; identify more proteins and their modifications; quantify their levels more accurately; and increase capacity of the Bristol Proteomics Facility, allowing greater user access and hence enhance health scien ce research."; "2016-12-22"; "2019-08-31"; "2020-12-08"; "2014-09-01"; "399998.0". a ; "UK Pubmed Central - Wellcome Trust"; "Unravelling the impact of the mite Varroa destructor on the interaction between the honey bee and its viruses"; "Project Grant"; "Dr Ryabov, Eugene EV"; "GBP"; "UNKNOWN"; ; ; "0"; "0.0"; "No Data Entered"; "2016-12-22"; "2013-12-31"; "2020-12-08"; "2011-01-01"; "207973.0". a ; "UK Pubmed Central - Wellcome Trust"; "Molecular and cellular mechanisms of mouse fetal lung maturation."; "Project Grant"; "Dr Rawlins, Emma EL"; "GBP"; "UNKNOWN"; ; ; "0"; "0.0"; "Multipotent epithelial progenitors in the embryonic lung produce bronchiolar and then alveolar daughter cells. We will investigate the cellular and molecular mechanisms responsible for this bronchiolar to alveolar switch. The long-term aim of this research is to facilitate the development of therapeutic alveolargenesis. Key goals: 1. Cellular mechanism: determine if the bronchiolar to alveolar switch is intrinsic to the epithelium. We will transplant lineage-labelled multipotent epithelial progenitor cells into older, or younger, cultured lungs and quantitatively assess the fates of their daughters. 2. Molecular mechanism: define the minimal genes which are sufficient for the embryonic bronchiolar to alveolar switch. We will test which of the transcription factors expressed in the multipotent progenitors while they are producing alveolar descendents are sufficient to determine alveolar fate. The transcription factors will be ectopically expressed during the bronchiolar (pseud oglandular) phase of lung development in vitro. The molecular mechanisms of the phenotypes, in particular the transcription factor targets, will be determined in vivo. 3. Adult application: test the ability of the embryonic alveolar progenitor-specific transcription factors to convert postnatal progenitors from bronchiolar to alveolar fate. Transcription factors will be ectopically expressed in small numbers of postnatal bronchiolar progenitors in growing, steady-state, or injured animals."; "2016-12-22"; "2014-12-31"; "2020-12-08"; "2011-07-01"; "302491.0". a ; "UK Pubmed Central - Wellcome Trust"; "IVerbal Autopsy with Participatory Action Research (VAPAR): expanding the knowledge base through partnerships for action on health equity"; "Joint Health Systems Research Award"; "Dr D'Ambruoso, Lucia L"; "GBP"; "UNKNOWN"; ; ; "0"; "0.0"; "Health systems are increasingly considered in terms beyond 'building blocks' models, as complex, adaptive, human and relational. Despite the conceptual advances, people-centered health systems research methods remain underdeveloped. The proposed work will connect two issues: the lack of information on the health of people excluded from access to health systems, and the low utilisation of research evidence by health systems stakeholders. The proposal is to institutionalise a process to strengthen data on mortality registration, combine with local knowledge, and interpret, plan and act on this basis in the health system at different levels. The method combines Verbal Autopsy (VA) with Participatory Action Research (PAR). VA is a method to determine levels, causes and circumstances of deaths. In PAR, communities organise evidence for action. 3 phases are proposed. In Phase 1, a series of 3 reflection and action cycles will be conducted to generate evidence, analyse, plan and act. Data will be generated on levels, causes and circumstances of deaths (using VA) and on health needs and priorities for action (using PAR) with communities. Data will be analysed with provincial level policy makers, action plans will be developed and implemented by district-level practitioners, and progress will be re-assessed in subsequent cycles. In Phase 2, participants and researchers will evaluate the process using realist and political economy methods to understand changes in care, outcomes and progress towards health equity. In Phase 3, sustainability and transferability will be developed with authorities, research and technical groups, health systems stakeholders and communities in the study site, and to the public. The output will be a process based on international standards, that is contextually relevant in health systems at different levels, and capable of translating local priorities into actionable agendas for health systems strengthening as a means towards health equity."; "2017-09-05"; "2022-01-01"; "2020-12-08"; "2017-01-02"; "235156.0". a ; "UK Pubmed Central - Wellcome Trust"; "Structural basis of oligopeptidase regulation and catalysis: acylaminoacyl peptidase."; "Project funding"; "Dr Szeltner, Zoltan Z"; "GBP"; "UNKNOWN"; ; "0"; "0.0"; "2020-01-21"; "2004-12-31"; "2020-12-08"; "2002-01-01"; "187400.0". a ; "UK Pubmed Central - Wellcome Trust"; "New infrastructure for EM studies at the University of Leeds."; "Equipment & Resources"; "Professor Ranson, Neil NA"; "GBP"; "UNKNOWN"; ; ; ; "0"; "0.0"; "Electron microscopy is a major tool in structural biology. The EM unit within the Astbury Centre for Structural Molecular Biology at the University of Leeds operates a modern FEI T-F20 microscope for high-resolution work. For preliminary cryo-EM studies we rely on a JEOL 1200EX electron microscope that is now >20 years old, and becoming increasingly difficult and expensive to maintain. Furthermore, because of its unsophisticated vacuum system it is only marginally capable of working in cryo-mode , meaning cryo-specimen optimisation and training must actually be carried out on our T-F20. We wish to purchase an FEI G2-Spirit microscope to replace the obsolete instrument, together with a CCD camera and an FEI Vitrobot freezing apparatus. The new microscope will bring dramatic benefits to EM research in Leeds. It will enable rapid collection of low-resolution and preliminary cryo data to support the substantial portfolio of structural research in Leeds. Used in conjunction with the Vitrobot freezing apparatus, it will enable optimisation of specimen preparation for frozen-hydrated specimens, enhancing the productivity of our T-F20. Finally, it will improve our ability to properly train users for a scientific career in cryo-EM, and enhance the overall productivity of the EM unit."; "2016-12-22"; "2013-03-31"; "2020-12-08"; "2010-04-01"; "364689.0". a ; "UK Pubmed Central - Wellcome Trust"; "The role of the oxidative pentose phosphate pathway (OPP) in Helicobacter induced apoptosis in primary cultures of gastric cells from the Ferret."; "Miscellaneous"; "Dr Butler, RN"; "GBP"; "UNKNOWN"; ; "0"; "0.0"; "2020-01-21"; "2001-07-31"; "2020-12-08"; "2001-07-01"; "2230.0". a ; "UK Pubmed Central - Wellcome Trust"; "Dental professionalism and ethics: what does it mean in practice?"; "Research Fellowship in H&SS"; "Dr Trathen, Andrew A"; "GBP"; "UNKNOWN"; ; "0"; "0.0"; "No Data Entered"; "2016-12-22"; "2017-09-30"; "2020-12-08"; "2011-10-01"; "145396.0". a ; "UK Pubmed Central - Wellcome Trust"; "Training Programme in Translational Medicine and Therapeutics at the University of Cambridge."; "Translational Medicine & Therapeutics Programme Clinical PhD Fellow"; "Dr Papadopoulou, C"; "GBP"; "UNKNOWN"; ; ; "0"; "0.0"; "No Data Entered"; "2016-12-22"; "2014-08-07"; "2020-12-08"; "2010-09-01"; "172346.0". a ; ; "UK Pubmed Central - Wellcome Trust"; "Defining disease mechanisms in mouse models of chondrodysplasia."; "Senior Research Fellowship Basic Renewal"; "Prof Briggs, Michael MD"; "GBP"; "UNKNOWN"; ; ; "0"; "0.0"; "The aim of this Fellowship is to determine the mechanisms of long bone growth and to characterise disease processes in human skeletal dysplasia. To determine the mechanistic link between the expression of a mutant gene and the resulting disruption to long-bone growth I generated mouse models of PSACH-MED resulting from mutations in COMP and matrilin-3. I have shown that reduced bone growth in these models results from decreased chondrocyte proliferation and increased/spatially dysregulated apopt osis. This change in cell phenotype is most likely due to cell stress induced by the expression of the mutant gene products. I will now use a multidisciplinary approach to determine 1) the contribution of UPR and cell stress to growth plate dysplasia and reduced bone growth, 2) if changes in the structure and function of the cartilage ECM contribute to the disease process and 3) the relative contributions of intracellular and extracellular disease mechanisms to the overall pathophysiology of cho ndrodysplasia. These studies will provide essential insight in the pathology of PSACH-MED and suggest potential therapies. They will also have a major impact on our understanding of disease mechanisms in other forms of chondrodysplasia and a broad spectrum of inherited connective tissue diseases."; "2016-12-22"; "2014-12-31"; "2020-11-03"; "2009-01-01"; "1379510.0". a ; "UK Pubmed Central - Wellcome Trust"; "Neural substrates underlying auditory social cognition."; "Sir Henry Wellcome Postdoctoral Fellowship"; "Perrodin, Catherine C"; "GBP"; "UNKNOWN"; ; "0"; "0.0"; "How the mammalian brain recognizes and uses social cues to guide interactions with conspecifics is a central question in neuroscience. I propose to address this using a natural communicative behaviour in mice, in which males attract potential female mates by producing elaborate courtship songs in the ultrasonic range. This project proposes a unique research approach to study where and how auditory social signals are encoded in the mouse brain, and how these representations are used to guide beha vioural responses during social interactions. This will be achieved by combining an ethologically valid assay of natural female approach to males during courtship with large-scale neuronal ensemble recordings in auditory cortex to assess the neuronal representation of behaviourally relevant vocal sounds. Finally, the neuronal circuits causally involved in generating this social behaviour will be identified using molecular-genetic manipulations. Together, these three synergistic approaches will h elp clarify the neuronal substrates of auditory social cognition, and establish a mouse model of vocal interactions with important implications for the study and potential remediation of psychiatric disorders affecting social communication."; "2016-12-22"; "2020-08-31"; "2020-12-08"; "2016-09-01"; "250000.0". a ; ; "UK Pubmed Central - Wellcome Trust"; "Institutional Strategic Support Fund"; "Institutional Strategic Support Fund"; "Professor Screaton, Gavin GR"; "GBP"; "UNKNOWN"; ; "0"; "0.0"; "2018-01-02"; "2021-10-02"; "2020-12-08"; "2017-07-01"; "3000000.0". a ; "UK Pubmed Central - Wellcome Trust"; "Virulence characteristics of Shigella species isolated from children hospitalised at Kilifi County Hospital compared to community controls."; "International Masters Fellowship"; "Miss Amulele, Anne AV"; "GBP"; "UNKNOWN"; ; ; "0"; "0.0"; "Shigella is a serious burden on the health of children in impoverished regions and a significant cause of severe diarrhoea in travellers. In the proposed study, I seek to determine if the virulence characteristics of Shigella species isolated from hospitalized cases of diarrhoea differ from isolates obtained from hospitalized bacteraemia cases or from isolates obtained from community surveillance in order to understand the pathogenicity of the bacteria in the region that leads to hospitalization and to inform vaccine development. I also seek to determine the association between these virulence genes and host factors such as age, HIV status, malnutrition, presenting syndromes and case fatality in hospital. This will inform us on the distribution of these pathogenicity factors in Kilifi County and association with geographical region in years when outbreaks occurred."; "2016-12-22"; "2018-03-14"; "2020-12-08"; "2015-06-15"; "117258.0". a ; "UK Pubmed Central - Wellcome Trust"; "Capturing the neuronal ensembles underlying sleep and sedation."; "Investigator Award in Science"; "Prof Franks, Nicholas N"; "GBP"; "UNKNOWN"; ; "0"; "0.0"; "Our major overarching question is: what mechanisms and neural circuitry make sleep inescapable when we are tired and deprived of sleep? In fact, the drive to recovery sleep after prolonged sleep deprivation seems so strong, that it is akin to taking a sedative drug. So, our second major question is: do sedative drugs cause loss of consciousness by activating the same mechanisms and circuitry responsible for this deep recovery sleep?"; "2016-12-22"; "2020-09-30"; "2020-12-08"; "2015-10-01"; "931144.0". a ; "UK Pubmed Central - Wellcome Trust"; "Robotic crystallisation facility at King's College London."; "Equipment & Resources"; "Professor Sutton, Brian BJ"; "UNKNOWN"; ; ; "0"; "0.0"; "2016-12-22"; "2012-03-29"; "2020-11-17"; "2007-03-30"; "0.0". a ; "UK Pubmed Central - Wellcome Trust"; "Mechanical Phenotyping of Prostate Cancer Cells"; "Vacation Scholarships"; "Mr Muir, Adam A"; "GBP"; "UNKNOWN"; ; ; "0"; "0.0"; "This project will examine the possibility of differentiating between healthy and prostate cancer cells using a microfluidic device called a ‘hydrodynamic stretcher’. It will focus on the ability to offer very high throughput label free phenotyping of cells based on their mechanical properties alone. The specific goal of this project is to examine mixed cell populations using the stretching device to examine if it has sufficient sensitivity to distinguish between cells from different cancerous and PNT2 (healthy) prostate cell lines. In doing so the hope is a step towards better diagnostic and prognostic capabilities.

Prostate cancer is the most common male cancer in the UK, but suffers from challenges in accurate diagnosis and prognosis. There are a range of issues with the current tests for prostate cancer and these lead to many unnecessary procedures with often very serious and unpleasant side effects. In this project we will examine a new method which probes the mechanical properties of cells to test if they are cancerous or not, and to establish if we can distinguish between cancerous and health cells and also between cancer cells that are, for example, relatively benign and those that are more aggressive. This work is based on the fact that cancer cells tend to be more ‘squishy’ than healthy cells.

"; "2016-12-22"; "2016-08-26"; "2020-12-08"; "2016-07-04"; "2000.0".