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Published February 3, 2021 | Version v1
Journal article Open

ACNE VULGARIS, RECENT UPDATES ON PATHOPHYSIOLOGY, DIAGNOSIS AND TREATMENT- A SYSTEMIC REVIEW STUDY

Description

Background: Acne vulgaris is defined as inflammation in a chronic pattern of the pilosebaceous unit system consisting of hair follicle, hair shaft and sebaceous gland, acne is between the most common dermatological conditions worldwide, with an estimated 700 million people affected. Acne is labeled as a chronic disease due to its prolonged course, way of recurrence and relapse, and manifestations such as acute onset or slow onset. Moreover, acne causes a huge negative impact on psychological and social life. Acne vulgaris affects over 70% of teenagers, and persists beyond the age of 22 years in 4% of men and 15% of women. Lesions of acne may be manifested as inflammatory papules, comedones and pustules. In more severe cases it may develop into nodules and cysts. Moreover, it can cause scarring and psychological distress.

Methods: We conducted a systemic review study in which we used a wide range of databases, PubMed and Medline search engines searching for “Acne vulgaris pathophysiology, diagnosis and treatment”, we excluded any unrelated topics and excluded acne vulgaris with comorbidities. We included all researches that deal with acne in all sexes and all age-group and all races.

Results: We found 32 systematic reviews and observational studies that met our inclusion criteria. We excluded 21 articles which were not according to our inclusion criteria.

Conclusion: In conclusion, this study shows that the recent updates on the diagnosis and new treatments related to acne vulgaris is effective and it is a good step toward the new treatment modalities in our dermatology specialty. However, we need more researches to be conducted in Europe, middle-east targeting such important and crucial topics.

Key words: acne, acne vulgaris, diagnosis, pathophysiology, treatment.

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