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Germinoma talámico: reporte de caso

Navarro-Venebra, José Antonio; Rodríguez-Florido, Marco Antonio


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{
  "inLanguage": {
    "alternateName": "spa", 
    "@type": "Language", 
    "name": "Spanish"
  }, 
  "description": "<p><strong>RESUMEN</strong></p>\n\n<p>Los tumores de c&eacute;lulas germinales del Sistema Nervioso Central son neoplasias intracraneales poco frecuentes. Generalmente afectan a pacientes menores de 20 a&ntilde;os de edad. Los germinomas se desarrollan a lo largo de la l&iacute;nea media, principalmente en la regi&oacute;n de la gl&aacute;ndula pineal y supraselar. Cuando se localizan en el t&aacute;lamo y los ganglios basales, suelen asociarse a hemiatrofia cerebral. Estas neoplasias son sensibles a radiaci&oacute;n y quimioterapia, lo que les confiere un buen pron&oacute;stico, sin embargo cuando se presentan en el t&aacute;lamo o los ganglios basales se han reportado mayores tasas de recurrencia adem&aacute;s de representar un reto diagn&oacute;stico con los estudios de imagen, a diferencia de cuando se presentan en su localizaci&oacute;n habitual.</p>\n\n<p>&nbsp;</p>\n\n<p>&nbsp;</p>\n\n<p><strong>ABSTRACT</strong></p>\n\n<p>Germ cell tumors of the Central Nervous System are unusual intracranial neoplasms. They generally affect patients under 20 years of age. Germinomas develop along the midline, mainly on the pineal and suprasellar gland region. When located in the thalamus and basal ganglia, they are usually associated with cerebral hemiatrophy. These neoplasms are sensitive to radiation and chemotherapy, which provides a good prognosis, however when they occur in the thalamus or the basal ganglia, higher recurrence rates have been reported, representing a diagnostic challenge with imaging studies, contrasting with cases in the usual location.</p>", 
  "license": "https://creativecommons.org/licenses/by/4.0/legalcode", 
  "creator": [
    {
      "affiliation": "Anatom\u00eda Patol\u00f3gica, UMAE Hospital de Pediatr\u00eda  \"Dr. Silvestre Frenk Freund\", Centro M\u00e9dico Nacional Siglo XXI, Instituto Mexicano del Seguro Social. Ciudad de M\u00e9xico, M\u00e9xico.", 
      "@type": "Person", 
      "name": "Navarro-Venebra, Jos\u00e9 Antonio"
    }, 
    {
      "affiliation": "Anatom\u00eda Patol\u00f3gica, UMAE Hospital de Pediatr\u00eda  \"Dr. Silvestre Frenk Freund\", Centro M\u00e9dico Nacional Siglo XXI, Instituto Mexicano del Seguro Social. Ciudad de M\u00e9xico, M\u00e9xico.", 
      "@type": "Person", 
      "name": "Rodr\u00edguez-Florido, Marco Antonio"
    }
  ], 
  "headline": "Germinoma tal\u00e1mico: reporte de caso", 
  "image": "https://zenodo.org/static/img/logos/zenodo-gradient-round.svg", 
  "datePublished": "2021-02-02", 
  "url": "https://zenodo.org/record/4482788", 
  "keywords": [
    "Tumores de c\u00e9lulas germinales", 
    "ganglios basales", 
    "t\u00e1lamo", 
    "germinoma", 
    "patolog\u00eda", 
    "Germ cell tumors", 
    "basal ganglia", 
    "thalamus", 
    "pathology"
  ], 
  "@context": "https://schema.org/", 
  "identifier": "https://doi.org/10.5281/zenodo.4482788", 
  "@id": "https://doi.org/10.5281/zenodo.4482788", 
  "@type": "ScholarlyArticle", 
  "name": "Germinoma tal\u00e1mico: reporte de caso"
}
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