Journal article Open Access

Germinoma talámico: reporte de caso

Navarro-Venebra, José Antonio; Rodríguez-Florido, Marco Antonio

RESUMEN

Los tumores de células germinales del Sistema Nervioso Central son neoplasias intracraneales poco frecuentes. Generalmente afectan a pacientes menores de 20 años de edad. Los germinomas se desarrollan a lo largo de la línea media, principalmente en la región de la glándula pineal y supraselar. Cuando se localizan en el tálamo y los ganglios basales, suelen asociarse a hemiatrofia cerebral. Estas neoplasias son sensibles a radiación y quimioterapia, lo que les confiere un buen pronóstico, sin embargo cuando se presentan en el tálamo o los ganglios basales se han reportado mayores tasas de recurrencia además de representar un reto diagnóstico con los estudios de imagen, a diferencia de cuando se presentan en su localización habitual.

 

 

ABSTRACT

Germ cell tumors of the Central Nervous System are unusual intracranial neoplasms. They generally affect patients under 20 years of age. Germinomas develop along the midline, mainly on the pineal and suprasellar gland region. When located in the thalamus and basal ganglia, they are usually associated with cerebral hemiatrophy. These neoplasms are sensitive to radiation and chemotherapy, which provides a good prognosis, however when they occur in the thalamus or the basal ganglia, higher recurrence rates have been reported, representing a diagnostic challenge with imaging studies, contrasting with cases in the usual location.

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