January 24, 2019 Journal article Open Access

Pierre-Yves Martin; Sophie de Seigneux

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  <identifier identifierType="URL">https://zenodo.org/record/4354957</identifier>
  <creators>
    <creator>
      <creatorName>Pierre-Yves Martin</creatorName>
      <affiliation>Laboratory of Nephrology, Service of internal medicine specialties, Geneva University Hospitals, Geneva, Switzerland</affiliation>
    </creator>
    <creator>
      <creatorName>Sophie de Seigneux</creatorName>
      <affiliation>Laboratory of Nephrology, Service of internal medicine specialties, Geneva University Hospitals, Geneva, Switzerland</affiliation>
    </creator>
  </creators>
  <titles>
    <title>Nitric oxide protects against AKI by reprogramming metabolism</title>
  </titles>
  <publisher>Zenodo</publisher>
  <publicationYear>2019</publicationYear>
  <subjects>
    <subject>Nitric oxide</subject>
    <subject>Acute kidney injury</subject>
    <subject>Metabolism</subject>
  </subjects>
  <dates>
    <date dateType="Issued">2019-01-24</date>
  </dates>
  <language>en</language>
  <resourceType resourceTypeGeneral="JournalArticle"/>
  <alternateIdentifiers>
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  <relatedIdentifiers>
    <relatedIdentifier relatedIdentifierType="DOI" relationType="IsIdenticalTo">10.1038/s41581-019-0113-z</relatedIdentifier>
  </relatedIdentifiers>
  <rightsList>
    <rights rightsURI="https://creativecommons.org/licenses/by/4.0/legalcode">Creative Commons Attribution 4.0 International</rights>
    <rights rightsURI="info:eu-repo/semantics/openAccess">Open Access</rights>
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  <descriptions>
    <description descriptionType="Abstract">&lt;p&gt;New findings demonstrate that endothelial nitric oxide synthase regulates major metabolic pathways in the kidney proximal tubule, which confers protection against oxidative stress during acute kidney injury (AKI). These findings give new insights into AKI pathophysiology and nitric oxide biology , and identify new targets for the treatment of AKI.&lt;/p&gt;</description>
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