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The article presents studies of the effect of the microbiological preparation "Trichodermine", bio-organic fertilizers and growth regulators based on humic acids "Nagro", "Stimix", "BioLife" and mineral fertilizers (NPK) on the biological activity of the soil, the degree of disease caused by Alternaria capsici-annui Savul & Sandu and the yield of pepper in the field. It was found that the differences in the indicator "Biological Activity of the Soil" depend on the number of microorganisms, the composition (species diversity) and the percentage of the main Micromycetes. Organic products help to optimize soil health and reduce the total content of fungal colonies, and in the composition of Micromycetes, the fungus Trichoderma sp. is more common. When mineral fertilizers are applied, the number of fungal pathogens and toxin producers increases. A higher total yield was obtained in the variants with biological treatment. The yield increase is from 9% to 29%.
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