Project deliverable Open Access

D1.1 - Inventory and preliminary assessment on availability of commercial solutions for nanoprocesses monitoring

Maria Paulis; Jose Ramon Leiza; Miren Aguirre; Edurne Gonzalez; Ron Peters; Christian Hill; Marko Simic; Nicola Pombo; Laurent Philippet; Heidy Ramirez; Roland Haas; Simona Neri


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  <identifier identifierType="DOI">10.5281/zenodo.4108910</identifier>
  <creators>
    <creator>
      <creatorName>Maria Paulis</creatorName>
      <nameIdentifier nameIdentifierScheme="ORCID" schemeURI="http://orcid.org/">0000-0002-7000-1231</nameIdentifier>
      <affiliation>University of the Basque Country UPV/EHU</affiliation>
    </creator>
    <creator>
      <creatorName>Jose Ramon Leiza</creatorName>
      <nameIdentifier nameIdentifierScheme="ORCID" schemeURI="http://orcid.org/">0000-0001-9936-7539</nameIdentifier>
      <affiliation>University of the Basque Country UPV/EHU</affiliation>
    </creator>
    <creator>
      <creatorName>Miren Aguirre</creatorName>
      <affiliation>University of the Basque Country UPV/EHU</affiliation>
    </creator>
    <creator>
      <creatorName>Edurne Gonzalez</creatorName>
      <nameIdentifier nameIdentifierScheme="ORCID" schemeURI="http://orcid.org/">0000-0001-5574-8217</nameIdentifier>
      <affiliation>University of the Basque Country UPV/EHU</affiliation>
    </creator>
    <creator>
      <creatorName>Ron Peters</creatorName>
      <nameIdentifier nameIdentifierScheme="ORCID" schemeURI="http://orcid.org/">0000-0002-3642-5022</nameIdentifier>
      <affiliation>DSM, NL</affiliation>
    </creator>
    <creator>
      <creatorName>Christian Hill</creatorName>
      <affiliation>Medical University of Graz, AT</affiliation>
    </creator>
    <creator>
      <creatorName>Marko Simic</creatorName>
      <affiliation>Medical University of Graz, AT</affiliation>
    </creator>
    <creator>
      <creatorName>Nicola Pombo</creatorName>
      <affiliation>IRIS Technology Solutions S.L.</affiliation>
    </creator>
    <creator>
      <creatorName>Laurent Philippet</creatorName>
      <affiliation>IRIS Technology Solutions S.L.</affiliation>
    </creator>
    <creator>
      <creatorName>Heidy Ramirez</creatorName>
      <nameIdentifier nameIdentifierScheme="ORCID" schemeURI="http://orcid.org/">0000-0002-0315-3120</nameIdentifier>
      <affiliation>Arkema France SA</affiliation>
    </creator>
    <creator>
      <creatorName>Roland Haas</creatorName>
      <affiliation>PDW Anallytics GmbH</affiliation>
    </creator>
    <creator>
      <creatorName>Simona Neri</creatorName>
      <nameIdentifier nameIdentifierScheme="ORCID" schemeURI="http://orcid.org/">0000-0002-0112-9514</nameIdentifier>
      <affiliation>IRIS Technology Solutions S.L.</affiliation>
    </creator>
  </creators>
  <titles>
    <title>D1.1 - Inventory and preliminary assessment on availability of commercial solutions for nanoprocesses monitoring</title>
  </titles>
  <publisher>Zenodo</publisher>
  <publicationYear>2020</publicationYear>
  <subjects>
    <subject>Commercial solution assessment</subject>
    <subject>Monitoring of nanoprocesses</subject>
    <subject>Characterisation techniques</subject>
  </subjects>
  <dates>
    <date dateType="Issued">2020-09-18</date>
  </dates>
  <language>en</language>
  <resourceType resourceTypeGeneral="Text">Project deliverable</resourceType>
  <alternateIdentifiers>
    <alternateIdentifier alternateIdentifierType="url">https://zenodo.org/record/4108910</alternateIdentifier>
  </alternateIdentifiers>
  <relatedIdentifiers>
    <relatedIdentifier relatedIdentifierType="DOI" relationType="IsVersionOf">10.5281/zenodo.4108909</relatedIdentifier>
    <relatedIdentifier relatedIdentifierType="URL" relationType="IsPartOf">https://zenodo.org/communities/nanopat</relatedIdentifier>
    <relatedIdentifier relatedIdentifierType="URL" relationType="IsPartOf">https://zenodo.org/communities/nsc</relatedIdentifier>
  </relatedIdentifiers>
  <rightsList>
    <rights rightsURI="https://creativecommons.org/licenses/by/4.0/legalcode">Creative Commons Attribution 4.0 International</rights>
    <rights rightsURI="info:eu-repo/semantics/openAccess">Open Access</rights>
  </rightsList>
  <descriptions>
    <description descriptionType="Abstract">&lt;p&gt;While bulk materials have constant physical properties independent of their size, the physical and chemical properties of a nanoparticle are dictated by its size. Accurate characterisation of mean size, size distribution and shape is key to the efficient manufacturing of high-quality nanomaterials. The EU-funded NanoPAT project plans to use three new real-time analytical tools that overcome problems and limitations of conventional characterisation technologies. The new process analytical technologies (PAT) will be photon density wave spectroscopy, optofluidic force induction and turbidity spectrometry. The innovative technologies will be combined with new data analysis methods to provide, for the first time, real-time analysis of particles on the nanometre scale with sub-minute temporal resolution.&lt;/p&gt;

&lt;p&gt;&amp;nbsp;&lt;/p&gt;

&lt;p&gt;The present document shows a summary of the &lt;strong&gt;most relevant characterization techniques used to measure particle sizes and size distribution&lt;/strong&gt;. These techniques are classified in three main approaches depending on the particle size distribution (PSD) analysis, which are ensemble, separation and counting methods. Each of the methods explained in the present document are based on different physical principles and present their own advantages and limitations. Only few of the techniques reviewed are valid for &lt;em&gt;online/inline&lt;/em&gt; analysis.&lt;/p&gt;</description>
  </descriptions>
  <fundingReferences>
    <fundingReference>
      <funderName>European Commission</funderName>
      <funderIdentifier funderIdentifierType="Crossref Funder ID">10.13039/501100000780</funderIdentifier>
      <awardNumber awardURI="info:eu-repo/grantAgreement/EC/Horizon 2020 Framework Programme - Research and Innovation action/862583/">862583</awardNumber>
      <awardTitle>Process Analytical Technologies for Industrial Nanoparticle Production</awardTitle>
    </fundingReference>
  </fundingReferences>
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