Dataset Open Access

Smoking is associated with worse outcomes of COVID-19 particularly among younger adults: a systematic review and meta-analysis

Glantz, Stanton; Patanavanich, Roengrudee


MARC21 XML Export

<?xml version='1.0' encoding='UTF-8'?>
<record xmlns="http://www.loc.gov/MARC21/slim">
  <leader>00000nmm##2200000uu#4500</leader>
  <controlfield tag="005">20201016170959.0</controlfield>
  <datafield tag="500" ind1=" " ind2=" ">
    <subfield code="a">&lt;p&gt;Funding provided by: National Institute on Drug Abuse&lt;br&gt;Crossref Funder Registry ID: http://dx.doi.org/10.13039/100000026&lt;br&gt;Award Number: R01DA043950&lt;/p&gt;&lt;p&gt;Funding provided by: National Institutes of Health&lt;br&gt;Crossref Funder Registry ID: http://dx.doi.org/10.13039/100000002&lt;br&gt;Award Number: U54HL147127&lt;/p&gt;</subfield>
  </datafield>
  <controlfield tag="001">4086492</controlfield>
  <datafield tag="700" ind1=" " ind2=" ">
    <subfield code="u">University of California San Francisco Medical Center</subfield>
    <subfield code="a">Patanavanich, Roengrudee</subfield>
  </datafield>
  <datafield tag="856" ind1="4" ind2=" ">
    <subfield code="s">22435</subfield>
    <subfield code="z">md5:1f34cd9f04c18d468c467a431f96e35b</subfield>
    <subfield code="u">https://zenodo.org/record/4086492/files/COVID_DataSingleFile.dta</subfield>
  </datafield>
  <datafield tag="856" ind1="4" ind2=" ">
    <subfield code="s">1846</subfield>
    <subfield code="z">md5:542dea2a936434b63f7612422a77adaa</subfield>
    <subfield code="u">https://zenodo.org/record/4086492/files/DO_FILE_COVID2_BMC.do</subfield>
  </datafield>
  <datafield tag="542" ind1=" " ind2=" ">
    <subfield code="l">open</subfield>
  </datafield>
  <datafield tag="260" ind1=" " ind2=" ">
    <subfield code="c">2020-09-30</subfield>
  </datafield>
  <datafield tag="909" ind1="C" ind2="O">
    <subfield code="p">openaire_data</subfield>
    <subfield code="p">user-dryad</subfield>
    <subfield code="p">user-zenodo</subfield>
    <subfield code="p">user-covid-19</subfield>
    <subfield code="o">oai:zenodo.org:4086492</subfield>
  </datafield>
  <datafield tag="100" ind1=" " ind2=" ">
    <subfield code="u">University of California San Francisco Medical Center</subfield>
    <subfield code="0">(orcid)0000-0002-8357-8961</subfield>
    <subfield code="a">Glantz, Stanton</subfield>
  </datafield>
  <datafield tag="245" ind1=" " ind2=" ">
    <subfield code="a">Smoking is associated with worse outcomes of COVID-19 particularly among younger adults: a systematic review and meta-analysis</subfield>
  </datafield>
  <datafield tag="980" ind1=" " ind2=" ">
    <subfield code="a">user-covid-19</subfield>
  </datafield>
  <datafield tag="980" ind1=" " ind2=" ">
    <subfield code="a">user-dryad</subfield>
  </datafield>
  <datafield tag="980" ind1=" " ind2=" ">
    <subfield code="a">user-zenodo</subfield>
  </datafield>
  <datafield tag="540" ind1=" " ind2=" ">
    <subfield code="u">https://creativecommons.org/publicdomain/zero/1.0/legalcode</subfield>
    <subfield code="a">Creative Commons Zero v1.0 Universal</subfield>
  </datafield>
  <datafield tag="650" ind1="1" ind2="7">
    <subfield code="a">cc-by</subfield>
    <subfield code="2">opendefinition.org</subfield>
  </datafield>
  <datafield tag="520" ind1=" " ind2=" ">
    <subfield code="a">&lt;p&gt;&lt;strong&gt;Introduction: &lt;/strong&gt;Smoking impairs lung immune functions and damages upper airways, increasing risks of contracting and severity of infectious diseases.&lt;/p&gt;

&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;We searched PubMed for studies published from January 1-May 25, 2020. We included studies reporting smoking behavior of COVID-19 patients and progression of disease, including death. We used a random effects meta-analysis and used meta-regression and lowess regressions to examine relationships in the data.&lt;/p&gt;

&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;We identified 47 peer-reviewed papers with a total of 31,871 COVID-19 patients, 5,759 (18.1%) experienced disease progression and 5,734 (18.0%) with a history of smoking. Among smokers, 29.2% experienced disease progression, compared with 21.1% of non-smokers. The meta-analysis confirmed an association between smoking and COVID-19 progression (OR 1.56, 95% CI 1.32-1.83, p=0.001). Smoking was associated with increased risk of death from COVID-19 (OR 1.19, 95% CI 1.05-1.34, p=0.007). We found no significant difference (p=0.432) between the effects of smoking on COVID-19 disease progression between adjusted and unadjusted analyses, suggesting that smoking is an independent risk factor for COVID-19 disease progression. We also found the risk of having COVID-19 progression among younger adults (p=0.023), with the effect most pronounced among people under about 45 years old.&lt;/p&gt;

&lt;p&gt;&lt;strong&gt;Conclusions: &lt;/strong&gt;Smoking is an independent risk for having severe progression of COVID-19, including mortality. The effects seem to be higher among young people.&lt;/p&gt;

&lt;p&gt;&lt;strong&gt;Implications:&lt;/strong&gt; Smoking prevention and cessation should remain a priority for the public, physicians, and public health professionals during the COVID-19 pandemic.&lt;/p&gt;</subfield>
  </datafield>
  <datafield tag="024" ind1=" " ind2=" ">
    <subfield code="a">10.7272/Q6CF9NBQ</subfield>
    <subfield code="2">doi</subfield>
  </datafield>
  <datafield tag="980" ind1=" " ind2=" ">
    <subfield code="a">dataset</subfield>
  </datafield>
</record>
57
23
views
downloads
Views 57
Downloads 23
Data volume 454.2 kB
Unique views 46
Unique downloads 20

Share

Cite as