rcn;id;acronym;status;programme;topics;frameworkProgramme;title;startDate;endDate;projectUrl;objective;totalCost;ecMaxContribution;call;fundingScheme;coordinator;coordinatorCountry;participants;participantCountries;subjects;IDR;TDR;Title_Interdisciplinar*;Objective_interdisciplinar;Title_transdisciplinar;Obj_transdisiplinarity 210596;754285;NEWBREED;SIGNED;H2020-EU.1.3.4.;MSCA-COFUND-2016;H2020;Training a new breed of interdisciplinary researchers to respond to the opportunities and challenges of ageing;2017-09-01;2022-08-31;;"The ageing population is one of Europe’s and the world’s grand challenges for the 21st century. How to cope with populations that are living ever longer and understanding the processes and means of tackling and benefitting from such populations has already been studied in great detail. However, the studies have mostly been independent, in often almost unrelated areas. To look at ageing throughout the whole life-course from many different dimensions, and not just in elderly people, requires a new breed of interdisciplinary research who has been trained to work on the topic within a number of different disciplines within science and the humanities. NEWBREED will address this challenge through an interdisciplinary doctoral programme, developed and coordinated by Örebro University in Sweden, in cooperation with a network of hosting organisations. These organisation nodes will open up a large network of other organisations for secondments – academic, industries, NGOs, public sector etc. NEWBREED seeks to attract 16 ESRs from Europe and the rest of the world to undertake this interdisciplinary research training. We believe that the NEWBREED programme will provide just that new breed of researcher. Örebro University is especially qualified to run NEWBREED. The programme docks in well with one of the university’s new strategic areas, namely Food and Health and that there is an existing local doctoral programme within Successful Ageing, which has acted as a pilot. In addition, the university has been involved in many age-related EU projects. The programme is divided into four themes: Ageing and psychosocial adjustment, Ageing from a societal perspective, Ageing and the fourth industrial revolution, and The biology of ageing. We believe that the graduated doctoral students will have unique possibilities on the job market with their interdisciplinary and intersectoral experience and can provide especially interesting perspectives into this important field of research.";2511360;1255680;H2020-MSCA-COFUND-2016;/MSCA-COFUND-DP;OREBRO UNIVERSITY;SE;;;;1;0;1;4;0;0 201101;703071;MUSLIM-NLNO;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Muslims condemning violent extremism - An interdisciplinary analysis of public initiatives in the Netherlands and Norway 2001-2015;2016-06-01;2018-05-31;;The project comprehends an interdisciplinary study on the dilemma faced by Muslims whether or not to explicitly disavow violent extremism. It explores how Muslim organisations and youth groups in the Netherlands and Norway have responded to calls to publicly condemn violent extremism. Special attention is paid to how young Muslim women and men have used specific strategies to gain media coverage, and the gendered aspects of these strategies. The project aims to analyse recent historical developments in the two countries in theoretical and empirical depth, by studying public debates and specific public initiatives undertaken by Muslims in the aftermath of the 9/11 attacks in 2001, the murder of Theo van Gogh in the Netherlands in 2004, and the 22/7 attacks by Anders Behring Breivik in Norway in 2011. It combines a comparative historical approach with theory and methodology of religious-, media-, cultural- and gender studies. The project fills an important gap in the growing body of research on Muslims in Europe: a lot of scholarly attention is paid to public discourses that stigmatise Muslims, but far less on how people with a Muslim background confirm or subvert dominant images in their interactions with the media. Scholars have described the pressure that young Muslims perceive to explicitly disavow terrorism, but a thorough analysis of their responses has yet to be made. The project will contribute to the understanding of the mechanisms of social cohesion in contemporary European society at a time of growing global threats. Hosting arrangements at the Department of Philosophy and Religious Studies at Utrecht University guarantee excellent training and research facilities. The vibrant interdisciplinary research network at the Department and the intense supervision by the awarded professor of religious studies Birgit Meyer will greatly contribute to the project and strengthen the interdisciplinary knowledge, skills and research network of the Experienced Researcher.;177598,8;177598,8;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;UNIVERSITEIT UTRECHT;NL;;;;1;0;1;3;0;0 214416;793095;CLAIMS;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;CLAIMing land in early medieval localitieS: an interdisciplinary study of land claims and property regimes in the north-west of the Iberian Peninsula (9th-11th);2019-02-01;2021-01-31;;What did it mean to own land in early medieval European localities? Research has so far largely concentrated upon historiographical questions such as the relationship between property and power and lords to peasant relations. However, much less attention has been paid to the crucial issue of how claims to land were laid, maintained and contested over time. CLAIMS arises from a concern to analyse the everyday dynamics of land claims. Its main goal is to develop an interdisciplinary framework for the study of land claims that can account for the different ways in which actors formulated, enacted, and engaged with each other’s land claims and in which these relationships became embedded in the local landscapes. This will enhance our understanding of the everyday processes of conflict and negotiation that shaped early medieval local property regimes. With Europe as its wider horizon, the project will focus on the north-west of the Iberian Peninsula between the 9th-11th centuries. The area provides us with a rich, coherent corpus of written sources and allows for a comparative assessment of a wide variety of scenarios. It thus offers a solid empirical basis to underpin the development of an interdisciplinary methodology for the study of land claims. Led by Dr Álvaro Carvajal Castro, CLAIMS will develop under the supervision of Dr Julio Escalona, a leading scholar in the study of early medieval societies. A well-planned programme of secondments with experts in Archaeology, Anthropology, and Geography will further contribute to reinforce the interdisciplinary nature of the project. CLAIMS will be based at the Centro de Ciencias Humanas y Sociales of the Spanish National Research Council (CCHS-CSIC), where a thriving multidisciplinary research environment, ample training opportunities, and the assistance of a solid management structure will support the fellow in the successful completion of the project.;158121,6;158121,6;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS;ES;;;;1;0;1;3;0;0 208565;745631;GRIDAMUS;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Greek Identity in Art Music since the Early Nineteenth Century: Towards an Interdisciplinary Methodology;2018-01-10;2020-01-09;;"This project is the first large-scale, interdisciplinary attempt to study mechanisms of national identity construction through modern Greek (post-1830) art music. It has two primary objectives: a) to develop an interdisciplinary methodological framework for the analysis of Greek art music drawing on historical musicology, Modern Greek Studies and ethnomusicology; and b) to offer a revisionist study of Greek art music – a repertory that remains to be investigated in the depth it merits – by exploring the ways in which it has mediated Greek identity during the period since the formation of the Greek nation-state in the early 19th century. Traditionally, the issue of “Greekness” – a perceived national character or identity – in music has been analysed with respect to the question of the assumed “continuity” of Greek history and culture since antiquity, as well as a quest for authenticity, purity, loyalty and uniqueness. Yet, such treatment of national identity is essentialising and self-exoticising. Recent scholarship on Greek music is starting to recognise the usefulness of contemporary methods of historical and cultural contextualisation. These approaches have much to gain from dialogue with a) recent critical discourses developed to understand and contextualise the concept of “Greekness” within modern Greek studies and b) ethnomusicological approaches to the study of music and identity. This project will equip me to become the first specialist on Greek art music to use an interdisciplinary methodology for the analysis of this music that draws on historical musicology, modern Greek studies and ethnomusicology, a method that has the potential to become paradigmatic for the study of other national repertories too and useful for other disciplines. The research will exploit archival sources while also drawing upon ethnographical methods. The outcomes will be: 1) a monograph, 2) two conference papers, 3) a series of public lectures and 4) a seminar series.";195454,8;195454,8;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;KING'S COLLEGE LONDON;UK;;;;1;0;1;3;0;0 203180;713548;WIRL;SIGNED;H2020-EU.1.3.4.;MSCA-COFUND-2015-FP;H2020;Warwick Interdisciplinary Research Leadership Programme;2017-01-01;2021-12-31;;"The Warwick Interdisciplinary Research Leadership Programme (WIRL) is a major new initiative by the University of Warwick to train future generations of Research Leaders in Europe. Warwick is known for its experience in interdisciplinary postdoctoral training through its leading Institute of Advanced Study (IAS), its innovative cross-sectoral research carried out through its ten Global Research Priorities (GRPs) and its international environment and reputation created through distinctive global partnerships and research collaborations. WIRL will build on this background to train 30 international researchers over five years to form a group of New Research Leaders who will contribute to the European Union’s plans to build a dynamic, knowledge-based economy and to improve economic growth. Warwick’s experience shows that Research Leadership is greatly enabled through close mentoring, international collaborations and the opportunity to build an independent research profile within the first five years of post-PhD research. Since 2007 the IAS has hosted a well-established research development programme, delivering complementary skills training to early career and experienced researchers. WIRL will be a major step forward in Warwick’s Postdoctoral training programme. It will expand the current UK-centred programme into one with a pan-European focus and global reach. WIRL will create an environment for Fellows to develop the skills and gain the experience required to become Research Leaders in their fields within and beyond academia. This research environment is underpinned by the University’s 10 interdisciplinary GRPs that sit across academic disciplines, representing Warwick’s key areas of research excellence and engagement. GRPs bring together research strengths from across the University, giving them clear thematic identities that show where Warwick can make a significant and distinctive contribution to the resolution of some of the world’s most pressing issues.";4012000;2006000;H2020-MSCA-COFUND-2015;/MSCA-COFUND-FP;THE UNIVERSITY OF WARWICK;UK;;;;1;0;1;3;0;0 211105;766139;HEART;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2017;H2020;HEalth related Activity Recognition system based on IoT – an interdisciplinary training program for young researchers;2017-09-01;2021-08-31;;"A current trend in healthcare involves the prevention of chronic diseases by changing behaviour towards more healthy lifestyle choices. This is supported by the increased use of wearable sensors and Internet of Things (IoT) devices. Human activity recognition and vital sign monitoring play a significant role in tailoring personal health and behaviour change coaching solutions to each individual, but pose a number of technical, legal, and socio-economic issues, which must be solved to enable a commercial viable solution. The IoT is a key growth business area for EU firms, which need to acquire competencies and skills for the exploitation of their innovation potential abroad. China is a key destination market, but products and solutions have to be tailored to the needs, behaviours and habits of Chinese consumer and to the specificity of the market. The goals of HEART project are: • to allow the formation of a team of 6 researchers, with a strong interdisciplinary attitude, integrating social science and humanities with high-end technical skills, creativity, innovation and entrepreneurial allure, with teamwork capabilities and ability to operate in the Chinese context for business in the domain of IoT and healthcare; • to release a health integrated activity recognition platform able to detect activities from heterogeneous data, using scalable algorithms, while safeguarding the privacy of the persons. A priority for the Non Academic beneficiary’s competitiveness is to deliver wearable technology for health monitoring, primary dedicated to healthy people (of \40 age) to penetrate the Chinese market; • to address the growing need of EU firms, for employees having the necessary skills (technical, legal and economic) in the IoT domain, thus increasing their international competitiveness. The consortium is composed of Philips, KU Leuven and the UNIMC with strong interdisciplinary experience in all relevant fields of HEART, supported by a network of partners in EU and China.";1527991,2;1527991,2;H2020-MSCA-ITN-2017;/MSCA-ITN-EID;UNIVERSITA DEGLI STUDI DI MACERATA;IT;"PHILIPS ELECTRONICS NEDERLAND B.V.;KATHOLIEKE UNIVERSITEIT LEUVEN";"NL;BE";;1;0;1;2;0;0 218195;814102;SWEET CROSSTALK;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2018;H2020;Training interdisciplinary glycoscientists to get a molecular-level grip on glycocodes at the human mucosa–microbiota interface;2019-01-01;2022-12-31;;"Sweet Crosstalk is a multidisciplinary European Training Network built to address the challenge of understanding, at a molecular level, how glycans are involved at the human mucosa–microbiota interface, and how this correlates with human well-being. Research into the human microbiome has reshaped the paradigm of our health and disease. In order to advance further, the time has arrived to understand it at a molecular level. Glycans dominate the microbiota-host interface and are thus ideally positioned to modulate these complex interactions. The research strategy of the Sweet Crosstalk programme focuses on optimal synergy between chemistry and biology. Smart chemistry drives the research to get a molecular-level grip on the role of these glycocodes and their interacting proteins, and advances in biology directs the research. The high quality and credibility of our consortium is ensured by a strong private-public partnership with complementary expertise ranging from chemical synthesis, biochemistry, structural biology to microbiology and cell biology. Our 7 academic groups are all renowned leaders in the glycoscience and microbiome fields, whereas the complementary 4 SMEs are specialized in glycan-based diagnostics and prophylactic therapies. This unique combination of scientific excellence and industry know-how covers the entire process from obtaining fundamental insight to the development of innovative early diagnostics and glycotherapeutics. Sweet Crosstalk also represents a unique research platform to train 15 outstanding Early Stage Researchers to be the new generation of innovative scientists with expert knowledge and skills in interdisciplinary glycoscience and human microbiome research. Our international, intersectoral and interdisciplinary training programme will equip them with the necessary scientific and transferable skills that will make them highly competitive for both top European research institutions and the healthcare/biotech job market.";4117674,96;4117674,96;H2020-MSCA-ITN-2018;/MSCA-ITN-ETN;UNIVERSITEIT UTRECHT;NL;"UNIVERSITEIT LEIDEN;HELSINGIN YLIOPISTO;INBIOSE NV;UNIVERSITA DEGLI STUDI DI NAPOLI FEDERICO II;UNIVERSITE CATHOLIQUE DE LOUVAIN;NUTRILEADS BV;UNIVERSITAT DE BARCELONA;GLYCOM AS;QUADRAM INSTITUTE BIOSCIENCE;ICENI DIAGNOSTICS LIMITED";"NL;FI;BE;IT;ES;DK;UK";;1;0;1;2;0;0 221090;854759;Lernwolke;SIGNED;"H2020-EU.3.;H2020-EU.2.3.;H2020-EU.2.1.";EIC-SMEInst-2018-2020;H2020;The first AI-driven smart-learning platform that teaches not only contents but also interdisciplinary skills as the key to success;2019-03-01;2019-06-30;;"In the era of interconnected world, we are still approaching teaching with methodologies from the industrial revolution. The result of the one-size-fits-all approach is (in EU) a 22% of underachivers in mathematics, 18% in reading and 17% in science. To maximize the potential of the future EU workforce (the students of today) we need a change of the teaching paradigm. We need to provide students with advanced tools for achieving their curricular goals but also, we need to coach them to develop their interdisciplinary competences (self-esteem, self-criticism, etc.) to unlock their true potential. Today, most schools do not have the resources (time & money) to provide individual learning and parents must support their children with private tutoring, that cost up to 1000€ per child per year. There are multitude of smart learning platforms today (Duolingo, Smartick, etc.) but they lack the capacity to develop student interdisciplinary competences. As a result, most students give up e-learning platforms after 3 weeks. Tobias and Michael, primary school teachers (IT background) have committed to change this paradigm by developing lernwolke. Lernwolke is an affordable Artificial Intelligence (AI)-driven learning platform that provides individual learning paths to each student. Our uniqueness, however, relies in the human component of our AI. Teachers and coaches, supported by the AI engine, help develop the emotional competences of each student and facilitate reaching their learning objectives and develop as a person. As there are no set goals, but the goals are adjusted to the capability of each student, lernwolke eliminates the concept of failure that is so detrimental for children. Our confidence in lernwolke relies in the 4000\ students from over 40 schools that have already validated the potential of our technology and the 16 letters of support received. With lernwolke we plan to reach an EBITDA of by 22M€ by 2025 (ROI 15,8) while increase our team by 12 members";71429;50000;H2020-SMEInst-2018-2020-1;/SME-1;LERNWOLKE GMBH;CH;;;;1;0;1;2;0;0 215537;797405;SHIPWORM;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;'A transregional and interdisciplinary study of the societal impact of the shipworm epidemic in the North Sea region in the eighteenth century';2018-09-01;2020-08-31;;"This transregional and interdisciplinary research proposal analyses the impact of the shipworm epidemic on coastal societies along the North Sea in the eighteenth century. The shipworm is a mollusc that scavenges floating or submerged wood in a marine environment. Lodged in the wooden hulls of returning East Indiamen, the shipworm was brought to Europe around 1730. Within a few years the shipworm had destroyed man-made wooden structures all along the North Sea coast. North-Western Europe faced an ecological disaster; the Low Countries were on the brink of flooding as the shipworms destroyed the wooden dikes, expensive harbour infrastructure was damaged beyond repair and numerous ships had to receive new hulls in order to keep afloat. The implemented solutions and reforms to minimise the shipworm’s effects were manifold and often had far reaching consequences. As such the shipworm’s societal impact was wide-ranged, as it spawned – to name a few examples – religious fanaticism resulting in mass executions of homosexuals in the Dutch Republic, political reforms in the Southern Netherlands, scientific interest in marine biology, a new international balance of power and innovative techniques in ship hull optimisation. This study is based on archival research and on an interdisciplinary approach in collaboration with marine biologists and hydrodynamic engineers. This approach determines the degree of innovation in shipping and its resulting economic efficiency. Boards representing copper sheathed, tar coated and uncoated ship hulls will be contaminated with shipworms and subsequently tested in a towing tank to measure the ships’ water resistance. The shipworm epidemic was an environmental crisis that had a large impact on the North Sea area. Through analysing several case-studies this research aims to show how and why these societies reacted as they did, why some ended up in deadlock and why others were able to turn the tide and profit from this crisis through innovation.";185076;185076;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;UNIVERSITE DE BRETAGNE OCCIDENTALE;FR;;;;1;0;1;2;0;0 203444;701647;PSI-FELLOW-II-3i;SIGNED;H2020-EU.1.3.4.;MSCA-COFUND-2015-FP;H2020;International, Interdisciplinary and Intersectoral Postdocs;2016-10-01;2021-09-30;;"Large-scale research facilities are enabling cutting edge research and innovation in important domains such as materials science, health and energy. A number of such accelerator facilities is currently under construction in Europe and will become operational within the next ten years. Thus, there is a growing need for highly qualified researchers trained in interdisciplinary research at such facilities and also an increasing demand from companies to use these facilities for developing and testing innovative products. The Paul Scherrer Institut (PSI), one of Europe’s leading research centres and particularly renowned for its accelerator facilities and long-standing industry collaborations, intends to establish a novel post-doctoral research programme with new interdisciplinary and inter-sectoral training elements. PSI features a unique combination of excellent research facilities, including neutron, muon and light sources and (as of 2016) an X-ray free electron laser, which all exceed the possibilities of universities or industrial research centres. Motivated by the successful implementation of the FP7 COFUND programme PSI-FELLOW, PSI now wants to take post-doctoral education to the next level and proposes to set up PSI-FELLOW-II-3I. This 5-year programme will offer a total of 60 fellowships of two years duration each. The fellowships will be awarded in two calls for proposals with 30 fellowships in each call. In order to maximise the benefit for the fellows and offer the widest possible range of research topics, PSI has teamed up with 16 partner organisations (9 research institutions and 7 companies). The unique setup of PSI-FELLOW-II-3i will allow using synergies with other leading research institutions for the training of the next generation of researchers specialised in tapping the full potential of large-scale research facilities, to transfer knowledge and stimulate innovation in Europe’s industries.";8496000;4248000;H2020-MSCA-COFUND-2015;/MSCA-COFUND-FP;PAUL SCHERRER INSTITUT;CH;;;;1;0;1;2;0;0 220192;822705;SHAPE-ID;SIGNED;H2020-EU.3.6.;GOVERNANCE-15-2018;H2020;Shaping Interdisciplinary Practices in Europe;2019-02-01;2021-07-31;;"A multitude of existing reports and assessments of AHSS (Arts, Humanities and Social Science) integration have made recommendations as to how best to encourage interdisciplinarity. However despite the existence of these reports much of their individual advice and recommendations have not been fully taken up. It is the overall aim of this project to provide concrete guidance and practical recommendations (in the form of a toolkit) for shaping future action, moving beyond expressions of intent or encouragement and into a framework for efficiently achieving the best value from activities in the interdisciplinary space. These recommendations will cover aspects such as the structure of IDR practices at the level of a research institution, the role of networks and consortia at an international level and the enabling structures such as programmes operated by research funders including national, pan-European and private research foundations. The toolkit will be an aid to the stakeholder groups being targeted by this project in achieving successful pathways to integration. These stakeholders have been grouped under 4 broad headings: 1. European Research Area (ERA) -Policy Makers and Funders (both national research funding agencies but also non governmental funders such as the Wellcome Trust, Leverhulme Foundation, the The Andrew W. Mellon Foundation) 2. Researchers (from across the AHSS and STEM disciplines both those engaging in IDR projects and those working in monodisciplinary cultures) 3. Research Performing Organisations (i.e. Universities, Academies of Sciences, Enterprise) 4. Research Users (Enterprise, Civil Society, the cultural sector and the citizen) The project will enable comparisons of IDR practices and results with reference to enhancing approaches to scholarship and to elaborating solutions for key Societal Challenges.";1499887,59;1499887,59;H2020-SC6-GOVERNANCE-2018;/CSA;THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN;IE;"ISTITUTO DI STUDI PER L'INTEGRAZIONE DEI SISTEMI (I.S.I.S) - SOCIETA'COOPERATIVA;INSTYTUT BADAN LITERACKICH POLSKIEJ AKADEMII NAUK;SPAAPEN JACOBUS;EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH;THE UNIVERSITY OF EDINBURGH";"IT;PL;NL;CH;UK";;1;0;1;2;0;0 209908;722046;ESIT;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2016;H2020;European School for Interdisciplinary Tinnitus Research;2017-04-01;2021-03-31;;"The European School for interdisciplinary tinnitus research (ESIT) provides an opportunity for young researchers to work on leading-edge research projects, which will radically improve the situation of 42 million European tinnitus patients. They will develop new treatment solutions for tinnitus, fundamentally improve existing treatment paradigms, implement innovative research methods, perform the first genetic studies on tinnitus and establish the largest pan-European tinnitus dataset, which will allow the implementation of innovative solutions for personalized tinnitus treatment. High quality network-wide training will prepare the individual researchers with outstanding academic as well as personal skills to perform these tasks. The international training programme offered by the ESIT network extends far beyond the doctoral training that can be offered by single universities. A distinctive feature of ESIT is therefore the tight integration of academic, clinical, and industrial partners together with patient organisations and public health authorities. Fellows will be trained by leading specialists from multiple domains and become familiar with the various work environments in the European health sector. The strong intersectoral and interdisciplinary training provides them with all relevant skills and experiences to excel internationally, to recognise their full potential and to take mature career decisions. ESIT will thereby build up a future generation of creative, entrepreneurial and innovative researchers for the European Research Area, trained to master the upcoming challenges in the field, to implement sustained changes in the clinical management of tinnitus, and to shape PhD education programmes for forthcoming students.";3823896,6;3823896,6;H2020-MSCA-ITN-2016;/MSCA-ITN-ETN;KLINIKUM DER UNIVERSITAET REGENSBURG;DE;"ISTITUTO DI RICERCHE FARMACOLOGICHE MARIO NEGRI;UNIVERSITAET ULM;ACADEMISCH ZIEKENHUIS GRONINGEN;UNIVERSITEIT MAASTRICHT;PARIS-LODRON-UNIVERSITAT SALZBURG;UNIVERSITAT ZURICH;THE UNIVERSITY OF NOTTINGHAM;KAROLINSKA INSTITUTET;UNIVERSYTET MEDYCZNY W LODZI.;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FUNDACION PARA LA INVESTIGACION BIOSANITARIA DE ANDALUCIA ORIENTAL-ALEJANDRO OTERO";"IT;DE;NL;AT;CH;UK;SE;PL;FR;ES";;1;0;1;2;0;0 213841;796917;DIS-ABLED;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Past Lifeways and Deathways of the Disabled in 14th-18th Century Central Europe: an Interdisciplinary Study;2018-08-01;2021-07-31;;"Disabled constitute around 20% of nowadays society and were a significant number in the past. The remains of disabled are part of archaeological heritage, and reconstruction of the life of the disabled enriches our understanding of common human heritage and the past. The goal of this project is to reconstruct lifeways and deathways of disabled in the 14th-18th century in Central Europe. As a result I expect to gain knowledge on: definition of disability, social status, gender, origin and burial customs of disabled as a group and individuals. I will investigate two populations (300 skeletons) from Poland as well as medical texts, chronicles and ethnographic sources from Central Europe that describe aspects of life and death of disabled. The project is highly interdisciplinary because it integrates archaeology (analysis of artefacts and graves), bioarchaeology (paleopathology, stable isotopes), history and ethnography (heuristic and hermeneutic analysis). These methods have not been linked before to study disability in archaeology. This project continues the socio-cultural approach in research on disability that emphasizes importance of archaeological and textual data to research on disability. This project extends this approach by developing interdisciplinary and cutting-edge methodology and studying new topics: the origin of disabled and new regions: Central Europe. The project will constitute the first comprehensive study on disabled from Central Europe and include them in academic narration, culture and social debate. The project will uncover heritage of disabled from Central Europe that is part of the European and worldwide heritage. Science communication activities will show the public the treatment of disabled in the past and help the disabled to understand their history better. Outreach and the knowledge gained from this project will help Europe become more inclusive, reflective and barrier-free.";251857,8;251857,8;H2020-MSCA-IF-2017;/MSCA-IF-GF;THE UNIVERSITY OF LIVERPOOL;UK;;;;1;0;1;2;0;0 218062;801512;E3I ECLAUSion;SIGNED;H2020-EU.1.3.4.;MSCA-COFUND-2017;H2020;Excellence, International, Intersectoral and Interdisciplinary doctoral training at Ecole Centrale Lyon in cotutelle with royal melbourne institute of technology AUStralia;2019-09-01;2024-08-31;;"E3I ECLAUSion, a joint venture between Ecole Centrale de Lyon (ECL) and RMIT University, Melbourne Australia aims to build a highly nurturing and multi-faceted PhD training environment that would benefit the emergence (‘eclosion’) of the next generation - 10 doctoral fellows in 2 cohorts- of not only highly skilled researchers but also entrepreneurs with an international mind-set and interdisciplinary training. Specifically ECLAUSion, in line with the MSCA guidelines, the EU principles for Innovative doctoral training and the code of conduct, aims to i) Reinforce research excellence in ECL in partnership with RMIT and increase scientific output and international visibility; ii) Expand on existing doctoral programs by attracting highly promising international early career researchers to ECL and providing a nurturing environment with global reach (both in terms of scientific supervision, mentoring, working conditions, administrative support and social life). We envision two calls being organized, with 5 doctoral contracts per call being offered (total number of PhDs offered 10) so that every researcher can receive their PhD degree during the 5 years program; iii) Educate and train these ESRs; enhance their research and transferable skills with a 3i dimension by offering them Interdisciplinary research options, exposure to Industry (both at local, regional and international levels), and an inherently International network to maximise their opportunities and their emergence into successful professionals in their future careers iv) Leverage the existing rich biotech and ICT local/regional/global ecosystem and capitalise on it to develop new synergies between academia and the private sectors and more generally v) Strengthen EU-Australia research collaboration in key areas for investment and growth in particular in Health; Biotechnology, Environment; Energy; Information and communications technologies; Nanotechnologies, materials and production technology.";1569600;784800;H2020-MSCA-COFUND-2017;/MSCA-COFUND-DP;ECOLE CENTRALE DE LYON;FR;;;;1;0;1;2;0;0 196949;664726;EI3POD;SIGNED;H2020-EU.1.3.4.;MSCA-COFUND-2014-FP;H2020;EMBL Interdisciplinary, International and Intersectorial Postdocs;2015-12-01;2020-11-30;;"The EIPOD programme was developed in 2007 with the objective of making use of the excellent scientific environment available at EMBL to support an innovative fellowship programme focused on interdisciplinary research training for postdoctoral fellows. EI3POD is designed to enrich and significantly build upon the very successful EIPOD programme and bears a significant number of novel features for scientific collaboration as well as vocational skills training and career development. The I3 in EI3POD stands for: 1. Interdisciplinary 2. International/inter-institutional 3. Intersectorial It offers three different modules each focusing on one of the three “I’s” as an expansion and significant enrichment of the original EIPOD scheme. All postdoctoral candidates applying under the EI3POD scheme will be offered the choice from among these three specializations. The specialization process will be supported by a career development advisor and accompanied by a set of training requirements to prepare candidates for making informed decisions about their project direction and career goals.";12744000;6372000;H2020-MSCA-COFUND-2014;/MSCA-COFUND-FP;EUROPEAN MOLECULAR BIOLOGY LABORATORY;DE;;;;1;0;1;2;0;0 202606;682529;PLANTCULT;SIGNED;H2020-EU.1.1.;ERC-CoG-2015;H2020;Identifying the food cultures of ancient Europe: an interdisciplinary investigation of plant ingredients, culinary transformation and evolution through time;2016-04-01;2021-03-31;;The project seeks to explore culinary practice among early farming European communities, from the Aegean to Central Europe, spanning the Neolithic through to the Iron Age (7th-1st millennia BC). The project seeks to identify the ‘food cultures’ of prehistoric Europe, and to reconstruct how cultivated and wild plant foods were transformed into dishes exploring their underlying cultural and environmental contexts and their evolution through time. The project will explore how culinary identities were shaped through the selection of plant foods both in terms of ingredients as well as processing and cooking practices. Thus not only species and meals but also the equipment involved in plant food preparation will be considered for the study area, linking the end product to the relevant technologies of transformation. Macroscopic and microscopic examination of the archaeological finds and experimental replication of various aspects of food preparation techniques informed by ethnographic investigations will form the main analytical tools. The interdisciplinary and contextual examination of the archaeological record will provide a fresh insight into prehistoric cuisine in Europe, the transformation of nature to culture through cooking. The project will revolutionise perceptions of prehistoric food preparation providing insights for the ‘longue durée’ of traditional plant foods constituting Europe’s intangible cultural heritage.;1891875;1891875;ERC-2015-CoG;/ERC-COG;ARISTOTELIO PANEPISTIMIO THESSALONIKIS;EL;"UNIVERSITAT BASEL;UNIVERSITAT WIEN;OESTERREICHISCHE AKADEMIE DER WISSENSCHAFTEN;UNIVERSITAET HOHENHEIM";"CH;AT;DE";;1;0;1;1;0;0 205609;722416;CHEurope;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2016;H2020;Critical Heritage Studies and the Future of Europe_Towards an integrated, interdisciplinary and transnational training model in cultural heritage research and management;2016-11-01;2020-10-31;;"CHEurope focuses on developing a new integrated theoretical and methodological framework to enhance the academic and professional training and open future job opportunities in cultural heritage preservation, management and promotion. Heritage has commonly been perceived through its contingent relationship to other areas, preventing it to be considered as a ‘legitimate’ scientific discipline. Moreover, research and practice in this field are still too often seen as separate dimensions. Thus, there is an increasing need to address these diverging trends in the expanding heritage industry with a critical approach that situates cultural heritage in its social, economic and political frameworks, as well as in professional practice. Bringing together a network of key European academic and non-academic organisations, the project will explore the processes by which heritage is ‘assembled’ through practice-based research in partner institutions that connect students to their future job markets and publics. Our aim is to inform more conventional aspects of cultural heritage designation, care and management with a strong focus on present and future consumers. We propose an advanced learning strategy based on the emerging field of Critical Heritage Studies, which combines theoretical and instrumental knowledge at a transnational and interdisciplinary level, in a series of research seminars, summer schools and secondments. The program is based on themes where cultural heritage is undergoing profound change, such as Heritage Futures, Curating the City, Digital Heritage, Heritage and Wellbeing and Management and Citizen Participation. In so doing, this research will have a direct impact on future heritage policies and be linked explicitly to new modes of training. These will enable future practitioners to facilitate a more democratic and informed dialogue between and across various heritage industries and their users, promoting entrepreneurship and innovation in this field.";3867561;3867561;H2020-MSCA-ITN-2016;/MSCA-ITN-ETN;GOETEBORGS UNIVERSITET;SE;"UNIVERSITEIT HASSELT;INSTITUTO UNIVERSITARIO DE LISBOA;AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS;ISTITUTO PER I BENI ARTISTICI CULTURALI E NATURALI DELLA REGIONE EMILIA ROMAGNA;UNIVERSITEIT UTRECHT;UNIVERSITY COLLEGE LONDON;UNIVERSITEIT VAN AMSTERDAM";"BE;PT;ES;IT;NL;UK";;1;0;1;1;0;0 205587;721975;in3;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2016;H2020;An integrated interdisciplinary approach to animal-free chemical and nanomaterial safety assessment;2017-01-01;2020-12-31;;All chemicals whether they are drugs, cosmetics, agrochemicals or others need to be tested for their safety to man and the environment. The use of whole animal studies for the prediction of adverse effects in man, is problematic due to species dependent effects, high costs and a large burden to animals in terms of numbers and suffering. While there have been major improvements in human in vitro and in silico techniques, there is still a lack of an integrated risk assessment platform. The in3 proposal aims to significantly further the development of animal-free chemical and nanomaterial (NM) safety evaluation by creating a scientific and training program aimed at integrating human in vitro testing with computational approaches. The project will focus on human induced pluripotent stem cells (hiPSC) derived tissues, including liver, kidney, brain, lung and vasculature and to utilise mechanistic toxicology, quantitative adverse outcome pathways, biokinetics, cheminformatics and modelling approaches to derive testable prediction models. hiPSC present the major advantages provide non-cancerous derived tissues with identical genetic backgrounds. All Early Stage Researchers (ESRs) will work towards the same goal, utilising the same chemicals, donor cells, assays and software packages. All data will be centrally housed in standardised formats, appropriately annotated and linked with protocols and material information. While ESRs will hone their skills in their own field of expertise, they will also collaborate to create an in depth safety evaluation testing platform for the chosen test compounds. By interaction, problem solving, training and secondments over the three years, they will acquire a unique set of interdisciplinary skills for chemical and NM safety assessment. The project aims to accelerate the realisation of animal-free safety assessment and to graduate 15 PhD students with the ideal skill sets to carry out the strategy designed in in3 in the near future.;3860843,4;3860843,4;H2020-MSCA-ITN-2016;/MSCA-ITN-ETN;STICHTING VU;NL;"NEWCELLS BIOTECH LIMITED;UNIVERSITE DE LAUSANNE;ISTITUTO DI RICERCHE FARMACOLOGICHE MARIO NEGRI;DOUGLAS CONNECT GMBH;BIOTALENTUM TUDASFEJLESZTO KFT;LIVERPOOL JOHN MOORES UNIVERSITY;KEMIJSKI INSTITUT;Department of Health;MEDIZINISCHE UNIVERSITAT INNSBRUCK;UNIVERSITEIT UTRECHT;EVERCYTE GMBH;UNIVERSITE D'ARTOIS;KATHOLIEKE UNIVERSITEIT LEUVEN";"UK;CH;IT;HU;SI;AT;NL;FR;BE";;1;0;1;1;0;0 215652;798555;FaMInART;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;“Family Making in India through Adoption or Reproductive Technology ”An interdisciplinary investigation of preference of Indian couples experiencing infertility regarding means of family formation;2019-07-01;2021-12-31;;"The goal of this research project is to understand the socio-cultural and regulatory factors influencing preference of married couples in India suffering from infertility or subfertility regarding means of family formation. I will concentrate on two approaches to family formation; adoption of a child(ren) and assisted reproductive technologies (ARTs) using gamete (egg and/or sperm) donation. The study will focus on Indian couples who are residents of India and exclude members of the Indian diaspora who travel to India seeking adoption and/or ARTs. The objective of the research project will be achieved through three interconnected work packages each with specific research questions and methodology. The first work package involves a systematic literature review of factors influencing uptake of adoption as a means of family formation in India and globally. The second work package comprises of a normative analysis of Indian regulatory frameworks on adoption and use of ARTs (using gamete donation) in comparison to key international and European regulations. The last work package is designed to explore values, decision making process and experience of intending Indian parents regarding their chosen means of family formation using qualitative research methods. The insights generated from this project will be relevant for evidence based regulatory approaches to ARTs and adoption not only in India and other low-resource countries but also for global regulation of cross-border reproductive care. This interdisciplinary research project will be situated at the Bioethics Institute Ghent (BIG) with a secondment to the department of Reproductive Health and Research (RHR) at WHO Geneva for four months at the end.";172800;172800;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;UNIVERSITEIT GENT;BE;;;;1;0;1;1;0;0 215572;797880;FSCF;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Alternative Families Social Change: An interdisciplinary and cross-national study;2018-09-01;2020-08-31;;"Single mothers by choice constitute an alternative to dominant notions of family. The Human Fertilisation and Embryology Authority (2015) found that there has been a 226% increase in the number of women choosing to go through IVF alone in the UK since 2006. The number has increased fourfold in Spain in the last seven years. This study will examine alternative motherhood constituted through in the UK and in Spain and will investigate four interconnected themes: a) being a mother and being mothered are both permeated with socio-cultural, political, economic and psychological significance as everyone has an interest in the social organisation of motherhood, although these interests vary; b) at the same time inequalities involving ethnicity, class and sexual orientation, can be particularly powerful in relationship to mothering; and c) the struggle over the question of how best to reorganise social institutions, such as workplaces and schools, so that they adjust to mothering, women´s freedom and equal opportunity. Ethnographic methods will be used to construct a more holistic understanding of the complexities of politics, policy and power from an interdisciplinary perspective. This study will broaden our knowledge of the ways in which discourses of mothering and motherhood both shape and are shaped by various practices, constraints and experiences cross-nationally. There is little research on the connection between gender ideology and family structure, specifically single mothers by choice, therefore this study will address whether motherhood may be a site for social change for women so that they raise children who do not conform to gendered expectations and stereotypes that are damaging to children and to society. This research is relevant to H2020 Societal Challenges 6 and 7, as it will examine the international gender dimension of motherhood and social change as well as exploring what gender equality means and entails across two European countries.";195454,8;195454,8;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;UNIVERSITY COLLEGE LONDON;UK;;;;1;0;1;1;0;0 215739;799544;GeoFodder;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;The scale and significance of early animal husbandry in SW Europe: development of aninterdisciplinary high-resolution approach to the investigation of livestock diets and herding practices.;2019-03-27;2021-03-26;;"In the history of early farming, the absolute scale and relative importance of livestock and crop husbandry, their degree of integration, and their landscape impact are largely obscure. To address this issue, GeoFodder will develop for the first time an interdisciplinary methodology that integrates geoarchaeological and archaeobotanical techniques for archaeological recognition of leafy browse and leafy fodder (currently not directly detectable) and for assessing the preservation of different plant resource types, with the ultimate aim of reconstructing early livestock diet and herding practices. To achieve these objectives, an innovative ethnoarchaeological and experimental programme will study present-day livestock penning deposits (for which herding practices, animal diets and depositional processes are known) to determine how dietary and other plant components are altered and partly preserved through ingestion, organic decay and (to sterilize pens) burning. This will generate a suite of geoarchaeological and archaeobotanical proxies, for different plant types (taxa, anatomical parts, seasons) with different preservation histories (ingested, decayed, burnt), that will then be applied to analysis of prehistoric penning deposits in Iberian caves and rock-shelters. The resulting semi-quantitative data on livestock diet in particular contexts will underpin modelling of the qualitative and temporal dimensions of early livestock grazing/ browsing and foddering at intra- and inter-site levels to enable assessment of the potential scale of herding and thus of the likely mobility of livestock and relative importance of crops and livestock in early farming. Geofodder will thus advance our understanding of early livestock husbandry in the SW Mediterranean, contribute to assessment of the long-term landscape impact and sustainability of herding, and establish methodological standards for investigating such questions in other regions and periods.";183454,8;183454,8;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;THE UNIVERSITY OF SHEFFIELD;UK;;;;1;0;1;1;0;0 209004;750296;CaraSlug;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Carabids as biocontrol agents for slugs in Oregon and Ireland - a novel and interdisciplinary approach to determine key malacophagous species and beneficial management options;2017-10-01;2020-09-30;;One of the challenges identified under Horizon 2020 is the building of a sustainable agri-food industry. Agricultural pests such as slugs are major contributors to financial losses in the farming sector and the use of pesticides, which is currently the mainstay of control, is an unsustainable management option due to their toxicity to non-target species and consumers but also because of their cost and variable efficacy. Biocontrol poses a more sustainable approach to pest control, but the only commercially available agent against slugs is the nematode Phasmarhabditis hermaphrodita which is ineffective against a number of key pest species, has a short shell life and is not permitted in countries outside of Europe (e.g. USA). CaraSlug aims to assess the potential of native carabid species as biocontrol agents against slug pests in Oregon and Ireland. For the first time, high-throughput sequencing and real-time PCR will be used in combination to analyse the gut contents of carabids collected over one year from vulnerable crops. Carabid species which are found to feed extensively on slugs and are abundant in crops at times when major slug damage occurs will be selected for feeding trials in the laboratory to further understand their feeding behaviour and biocontrol potential. By comparing the abundance of both pest and predator species and by determining the availability of alternative prey in differently managed crops e.g. with and without beetle banks over a year, management systems which provide optimum conditions for malacophagous carabid species will be identified. This project is interdisciplinary, combining ‘classic’ ecology and environmental management approaches with the latest advances in molecular biology and both the experienced researcher and the hosts will benefit greatly from the combined team’s expertise. By directly involving farmers in our research, this project will also form an important link between academia and the community.;248063,4;248063,4;H2020-MSCA-IF-2016;/MSCA-IF-GF;NATIONAL UNIVERSITY OF IRELAND GALWAY;IE;;;;1;0;1;1;0;0 210346;754364;EMPAPOSTDOCS-II;SIGNED;H2020-EU.1.3.4.;MSCA-COFUND-2016;H2020;EMPAPOSTDOCS-II MSCA COFUND International, interdisciplinary, inter-sectoral PostDoc Fellowship Programme at Empa;2017-05-01;2022-04-30;;"After successfully applying for a first postdoctoral fellowship programme in 2010, Empa has decided to create a second fellowship programme: It will allow 50 experienced researchers from all over the world to create a research project and get the opportunity to work on their own research idea at one of the 30 research laboratories of Empa, in cooperation with a senior scientist of Empa of his/her choice. The training and mentoring scheme will ensure that the fellows not only enhance their scientific experience but also acquire key long-life skills making them “contributing players” of the research community and society in general. As an interdisciplinary research institution within the Swiss ETH Domain, Empa, the Swiss Federal Laboratories for Materials Science and Technology, conducts cutting-edge materials and technology research. Empa’s activities focus on meeting the requirements of industry and the needs of society, and thus link applications-oriented research to the practical implementation of new ideas in the areas of nanostructured, “smart” materials and surfaces, environmental, energy and sustainable building technologies as well as biotechnology and medical technology. Empa’s five research focal areas and three locations offer a large degree of freedom of research topic and destination for the applicants. The close cooperation of Empa with its industry partners ensures that the fellows will gain sufficient cross-sectorial experiences while being at Empa. Empa’s world-leading expertise in the various research fields and the close ties with industry offers a good balance of academic/research and industrial experience. The applicants will be evaluated by an internal and external selection committee of peer-reviewers according to strict selection criteria focusing on the applicants’ professional, personal, social and leadership skills and his or her research potential. The fellows will be offered an Empa contract of two years.";7080000;3540000;H2020-MSCA-COFUND-2016;/MSCA-COFUND-FP;EIDGENOSSISCHE MATERIALPRUFUNGS- UND FORSCHUNGSANSTALT;CH;;;;1;0;1;1;0;0 206707;702586;INpaCT;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-GF;H2020;An interdisciplinary approach to uncover the mechanisms of progression of cartilage damage at the cellular and tissue levels;2017-01-01;2021-03-30;;Joint injuries are very frequent, especially among young people. Such injuries seldom heal and over time can lead to cartilage degeneration and ultimately osteoarthritis. Although, it is generally assumed that excessive mechanical loading post-injury can cause or accelerate the progression of cartilage degeneration, the precise mechanisms involved in the pathological processes at different structural length scales are still not fully understood. Thus, novel approaches for understanding structure-function relationships from the cell to tissue level in both health and disease are necessary. The overall aim of this research is to investigate the mechanisms of cartilage damage progression at different levels of tissue organization. The novelty of this research lies in the highly interdisciplinary approach of combining an in vitro model of OA progression with the state-of-the-art materials testing devices, computational modeling and sophisticated microscopic, spectroscopic and molecular biology techniques to carefully assess the mechanics, structure, composition and gene expression on cell and tissue levels. The novel data obtained from this research will shed light on the key mechanobiological pathways by which cartilage cells maintain healthy tissue or mount a healing response following tissue injury and excessive loading. This project is conducted as an international collaboration between University of Eastern Finland, Kuopio, Finland and Massachusetts Institute of Technology, Cambridge, USA. This represents a unique opportunity to bring together the complementary skill sets of Dr. Florea, Dr. Korhonen’s group and Prof. Grodzinsky’s group, with their expertise in biomechanics, computational modeling, biochemistry and cartilage biology. The mutually beneficial collaboration between Europe and USA can advance the field of cartilage research with significant potential to provide novel strategies to reduce/prevent cartilage degeneration for patients in Europe and beyond.;267793,2;267793,2;H2020-MSCA-IF-2015;/MSCA-IF-GF;ITA-SUOMEN YLIOPISTO;FI;;;;1;0;1;1;0;0 203493;706028;CoSMaS;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Developing an interdisciplinary Collaborative Self-Management Support model: behavioural and communication tools for integrated care;2017-04-03;2019-04-02;;The CoSMaS project aims to develop and test an interdisciplinary Collaborative Self-Management Support Model applicable to several chronic health conditions and to validate model measurement tools for use in research and routine care. The proposed research investigates how different HCPs contribute to supporting self-management, how they coordinate care, and how this can be improved to ensure comprehensive (but not redundant) care and ultimately reduce illness burden. It thus addresses recent calls to improve chronic care in Europe, in line with recent advances towards integrated care and current interest in using social science, especially health communication and behaviour change, to inform health services research. Within a 2-year timeline, it proposes a community-based participatory research approach to develop solutions for collaborative care in France in asthma, stroke and cancer based on input from various stakeholders, while also developing the model internationally via collaborations with other EU research centres. Theoretical literature reviews are first planned to inform model development. Qualitative studies are set to explore the views of patients’, caregivers’ and health care professionals of different specialities on current and desired CoSMaS practices. An international Delphi consultation aims to reach consensus on model elements and hypotheses by synthesizing opinions of research and management experts. Self-report tools are developed, piloted and validated in a cross-sectional online survey. This research is linked to relevant training, knowledge transfer and communication activities to broaden the expertise of the researcher, valorize her current knowledge within the host and partner organizations, and disseminate scientific evidence on collaborative self-management support to scientific audiences and the public at large.;185076;185076;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;UNIVERSITE LYON 1 CLAUDE BERNARD;FR;;;;1;0;1;1;0;0 198631;648131;MMAF;SIGNED;H2020-EU.1.1.;ERC-CoG-2014;H2020;Novel multimodal approach to atrial fibrillation risk assessment and identification of targets for prevention by interdisciplinary exploitation of omics, advanced electrocardiography, and imaging;2016-01-01;2020-12-31;;"There is a growing need for novel risk schemes in atrial fibrillation (AF) to permit prevention, contribute to a better understanding of the pathophysiology, and discover targets for individualized treatment. Primary prevention efforts are scant despite the imminent AF epidemic. In international cohorts I have developed and validated the first risk prediction algorithm. However, it explains only 60% of the attributable risk and efforts at improving discrimination are urgently required. Therefore, my overall goal is to develop an enhanced risk prediction algorithm based on cutting-edge technology. The specific focus will be on parameters representative of early stages of the disease process and intermediate phenotypes such as atrial electrical and structural remodelling, chronic subclinical inflammation, oxidative stress, and autonomous tone in manifest and incident AF. Subclinical, potentially reversible changes are ideally suited to provide independent information complementary to known risk markers. My ambitious concept is to choose a multimodal approach in an interdisciplinary team to systematically assess: 1) Blood and tissue omics (genomics, expression, proteomics, metabolomics), 2) Advanced electrocardiography, 3) Imaging (echocardiography, cardiac MRI), and 4) Gender applying innovative tools and analyses strategies aimed at a systems biology integration of the accumulated information. I have collected comprehensive biological and epidemiologic information on distinct AF phenotypes in unique prospective population (N>60,000) and clinical cohorts (N>1,000). We are not aware of other groups with access to such a well-established prospective AF biobank. Informed by omics, electrocardiography and imaging we will provide pathophysiological insights into the disease process, highlight targets for intervention, and develop a contemporary risk scheme. Our results will lay the ground for rapid translation into clinical practice with significant public health impact.";1999305;1999305;ERC-2014-CoG;/ERC-COG;UNIVERSITAETSKLINIKUM HAMBURG-EPPENDORF;DE;;;;1;0;1;1;0;0 221968;835271;ROMETRANS;SIGNED;H2020-EU.1.1.;ERC-2018-ADG;H2020;Rome Transformed: Interdisciplinary analysis of political, military and religious regenerations of the city's forgotten quarter C1-C8 CE;2019-10-01;2024-09-30;;This project revolutionises our understanding of Rome and its place in cultural change across the Mediterranean World by mapping political, military and religious changes to the Eastern Caelian from the first to eighth centuries. The programme offers multiple gains for archaeologists, historians, topographers and geographers by documenting both the mundane and monumental elements of the city fabric in chronological, geographical and ideological relationship to one another. From the extravagant horti, the houses of elite families, through successive imperial palaces to the seat of papal governance the area’s architecture embodied changing expressions of political power. From the early military stations, through the grandeur of the barracks of the emperor’s horse guards, to the building and rebuilding of the Aurelian Walls, it reveals notions about the intersection of security and military power. From the shrines of the early empire to the world’s first Cathedral, it attests successive religious regenerations. RomeTrans has three objectives: first, it determines the appearance of the buildings that drove these changes, producing academically robust visualisations, appropriately contextualised. Second, it brings these elements together to model the five transformations that saw the Eastern Caelian reshaped to meet the needs of shifting political, military and religious ideas. Third, it provides a longer-term interdisciplinary perspective on the changing shape of this pivotal area than any previously attempted. All this requires a survey of unprecedented scale and sophistication, demanding a new methodology for complex urban areas capable of transforming research in historic towns worldwide. Integrating documentary sources, architectural analysis, investigation of 11 sub-surface excavated areas with the largest geo-radar and laser scanning surveys ever conducted in Rome, the project transforms our approach to the city and its relationship to the wider world.;2425688,04;2425684;ERC-2018-ADG;/ERC-ADG;UNIVERSITY OF NEWCASTLE UPON TYNE;UK;"UNIVERSITA DEGLI STUDI DI FIRENZE;THE BRITISH SCHOOL AT ROME;CONSIGLIO NAZIONALE DELLE RICERCHE";IT;;1;0;1;1;0;0 211733;766124;PurinesDX;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2017;H2020;Interdisciplinary training network on the purinergic P2X7 receptor to control neuroinflammation and hyperexcitability in brain diseases.;2017-09-01;2021-08-31;;Brain disorders affect ~179 million people and their families in Europe alone, with an annual cost to the taxpayer estimated at €800 billion- a greater economic burden than cardiovascular disease and cancer combined. Despite diverse etiology, overlap in clinical symptoms and comorbidities between brain disorders suggests shared patho-mechanisms. In particular, hyperexcitible states driven by glial activation and neuroinflammation appear near ubiquitous. Targeting these mechanisms offers the potential to ameliorate symptoms and reverse disease progression across a broad span of brain disorders. Functioning as a gatekeeper to neuroinflammation and mechanistic link between neuronal hyperexcitability and glial activation, the ATP-gated, ionotropic purinergic P2X7 receptor (P2X7R) offers the most promising target for pharmacological intervention in the neuroinflammation-hyperexcitability pathway, to date. With breakthroughs in understanding P2X7R function, highly promising effects demonstrated for antagonists in models of brain disease and vast investment in P2X7R-related drug development programmes, now is the perfect time to pool resources. PurinesDX brings together global leaders in translational research in purinergic signalling, Europe’s leading clinical specialists in a broad range of brain diseases, and industrial partners specializing in drug and biomarker development. Sharing unique genetic tools, newly developed diagnostic devices and novel, selective and brain-stable P2X7R antagonists, the synergism facilitated within PurinesDX will extend to the training of an urgently needed new generation of highly skilled, innovative, creative and entrepreneurial scientists. Alongside the provision of this interdisciplinary, international and intersectoral environment, an original and high level training in state-of-the-art neuroscience will be provided, nurturing a cohort of highly competitive researchers with potential to drive a new era of neuroscience research.;3487463,28;3487463,28;H2020-MSCA-ITN-2017;/MSCA-ITN-ETN;ROYAL COLLEGE OF SURGEONS IN IRELAND;IE;"SARISSA BIOMEDICAL LIMITED;LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN;FUNDACION TEOFILO HERNANDO;BIOTALENTUM TUDASFEJLESZTO KFT;INSTITUTE OF EXPERIMENTAL MEDICINE - HUNGARIAN ACADEMY OF SCIENCES;UNIVERSIDAD COMPLUTENSE DE MADRID;CENTRO DE INVESTIGACION BIOMEDICA EN RED ENFERMEDADES NEURODEGENERATIVAS;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV";"UK;DE;ES;HU";;1;0;1;1;0;0 198111;675999;ITEAM;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2015-ETN;H2020;Interdisciplinary Training Network in Multi-Actuated Ground Vehicles;2016-01-01;2019-12-31;;"'The main target of the ITEAM project is to establish and sustainably maintain the European training network with high grade of interdisciplinarity, which will train strong specialists skilled in research and development of novel technologies in the field of multi-actuated ground vehicles (MAGV). The global goals are: (i) Advance of European postgraduate education in the area of environment- and user-friendly vehicle technologies that highly demanded by the European industry and society; (ii) Reinforcement of cooperation between academia and industry to improve career perspectives of talented graduates in both public and private sectors; (iii) Creation of strong European research and innovation group making determinant contributions to next generations of multi-actuated ground vehicles. To achieve the project objectives, the consortium unites 11 beneficiaries and 5 partner organizations from 9 European countries including 7 universities, 2 research centres, and 7 non-academic organizations. Distinctive feature of the ITEAM network is the concept of interaction of three research clusters: 'MAGV integration', 'Green MAGV', 'MAGV Driving Environment'. Within these clusters, the training concept will be based on intersectoral cooperation and will cover domains of (i) basic research, (ii) applied research, and (iii) experimentations. The ITEAM project will provide the first-of-its kind European training network in Ground Vehicles at doctorate level to fill up the niche in private sector and industry with researcher-practitioners. The proposed network will be developed as innovative, multidisciplinary, engineering product-oriented and project-based program to train the scientists by integrating cutting-edge research methods of ground vehicles, electric/mechatronic systems, environmental engineering and applied intelligent control. The ITEAM network measures will guarantee excellent career prospects for participating researchers both in industrial and academic sectors.'";3833413,2;3833413,2;H2020-MSCA-ITN-2015;/MSCA-ITN-ETN;TECHNISCHE UNIVERSITAET ILMENAU;DE;"COVENTRY UNIVERSITY;VOLVO PERSONVAGNAR AB;UNIVERSITE DE TECHNOLOGIE DE COMPIEGNE;SKODA AUTO A.S.;INFINEON TECHNOLOGIES AG;Kompetenzzentrum - Das Virtuelle Fahrzeug, Forschungsgesellschaft mbH;UNIVERSITA DEGLI STUDI DI PAVIA;AVL LIST GMBH;FLANDERS MAKE VZW;KATHOLIEKE UNIVERSITEIT LEUVEN";"UK;SE;FR;CZ;DE;AT;IT;BE";;1;0;1;1;0;0 198481;670446;Filmcolors;SIGNED;H2020-EU.1.1.;ERC-ADG-2014;H2020;Film Colors. An Interdisciplinary Approach.;2015-09-01;2021-05-31;;"Film is in essence colored light projected onto a screen. Its aesthetics are thus highly determined by the material properties of film and the optical configuration of the cinematic apparatus. To this day, however, there is no systematic study of the relationship between the technology and aesthetics of film colors, despite the fact that, following the digital turn in film production and distribution, the understanding of this relationship is more essential than ever before. Over 200 film color processes were developed since the invention of film. They are presented on the Timeline of Historical Film Colors, which will be an integral part of the project. The groundbreaking nature of this project lies in a truly interdisciplinary research design with a novel methodology to explore the interaction of technological advances and limitations with film color aesthetics, identifying diachronic patterns of stylistic means. To this end it develops a tool through recent advancements in digital humanities for crowd-sourcing of color analyses of large groups of films. In-depth studies of technical papers and scientific measurements of film colors will investigate the technical basis of films’ aesthetic appearance. These insights will be applied to the digitization and restoration of historical films to explore and disseminate the results. While every serious art restoration connects scientific analyses with art-historical and aesthetic investigations, a similar approach is rarely applied to film. In summary, the present research proposal capitalizes on the principal investigator’s preceding studies to bridge the gap between technology and aesthetics. With the methods described here, the results will trace previously hidden roots of aesthetic developments of film colors. While the project is ambitious, it builds on a sizable methodological foundation to optimize risk management and guarantee significant advances in the understanding of film colors.";2913143,75;2913143,75;ERC-2014-ADG;/ERC-ADG;UNIVERSITAT ZURICH;CH;;;;1;0;1;1;0;0 193963;642904;TreatRec;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2014-EID;H2020;Interdisciplinary concepts for municipal wastewater treatment and resource recovery. Tackling future challenges;2015-01-01;2018-12-31;;"Wastewater treatment and management in Europe has a large potential for growth; however needs to be supported by education of a new generation of interdisciplinarily trained wastewater professionals able to face future challenges and implement wastewater-related directives in practice. TreatRec, with the participationof two academic partners (ICRA-Catalan Institute for Water Research and University of Girona) and two non-academic (ATKINS and AQUAFIN) identifies several pertinent technological gaps and knowledge needs around which we have built a research programme. TreatRec involves equally academia and industry with a clear aim of producing a group of young researchers capable of conducting high quality research, but also able to address industrial and societal needs and implement wastewater-related directives in practice. The five researchers will conduct their scientific projects in an environment that combines industrial excellence in the development, design, construction and management of wastewater treatment systems, with complementary academic excellence in a) hypothesis-driven research involving the improvement/upgrading of state-of-the art technologies and the deepening the understanding of fate and removal of emerging contaminants in wastewater treatment systems and in b) applied research involving the development of decision support systems which allow for the encapsulation of knowledge for further use in decision-making processes. As a general goal, academic and non-academic partners of TreatRec, including WWTP operators, engineers responsible for the design and a water authority which has experience in water policy implementation, a set of recommendations will be generated to provide guidance for decision-makers on upgrading wastewater treatment plants for future challenges such as microcontaminants removal and nutrient recovery from a sustainable perspective.";1267466,76;1267466,76;H2020-MSCA-ITN-2014;/MSCA-ITN-EID;FUNDACIO INSTITUT CATALA DE RECERCA DE L'AIGUA;ES;"AQUAFIN N.V.;UNIVERSITAT DE GIRONA;ATKINS LIMITED";"BE;ES;UK";;1;0;1;1;0;0 218019;812954;EUROoC;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2018;H2020;Interdisciplinary training network for advancing Organ-on-a-chip technology in Europe;2018-12-01;2022-11-30;;EUROoC will create a trans-European network of industrially oriented specialists fully trained in development and application of the emerging Organ-on-a-chip (OoC) technology. OoC technology is advancing at breath taking pace due to its potential impact in drug development and personalised treatments of disease. New researchers entering this field must be equipped with a multidisciplinary background ranging from biology to microfluidic chip engineering. EUROoC will offer the first complete and coherent European training program on OoC by gathering multidisciplinary participants (biologists, physicists, chemists, engineers) in a multi-sectoral network composed of 4 companies (3 SMEs), 2 regulation entities and 10 academic institutions. EUROoC will qualify the next generation of interdisciplinary scientists for all aspects of OoC development and utilisation, including understanding of commercialisation pathways and regulatory aspects. EUROoC furthermore comprises a collection of innovative research projects addressing the development of advanced OoC systems with higher physiological significance going beyond current in vitro testing. The EUROoC project will create advanced OoCs, which closely recapitulate properties of the respective organ tissues in vivo regarding cell types, microenvironment, organ-specific tissue structure and function as well as concepts for the interconnection of individual OoCs. The various OoC models to be developed comprise heart-on-a-chip, bone-on-a-chip, retina-on-a-chip, lung-on-a-chip, adipose- on-a-chip, gut-on-a-chip to liver-on-a-chip. The OoC systems will be able to monitor and analyse tissue functionality and response in situ by integrating various novel sensing elements. The OoCs developed will be pre-validated with the regulatory partners through in vitro-in vivo correlations. The research and training program planned will increase European competitiveness sustainably in this emerging key technology.;3942860,76;3942860,76;H2020-MSCA-ITN-2018;/MSCA-ITN-ETN;FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.;DE;"ACADEMISCH ZIEKENHUIS LEIDEN;BUNDESINSTITUT FUER RISIKOBEWERTUNG;TECHNISCHE UNIVERSITAET GRAZ;MILTENYI BIOTEC GMBH;UNIVERSITEIT TWENTE;UNIVERSITAET BERN;UPPSALA UNIVERSITET;ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE;UNIVERSITE DU LUXEMBOURG;Universitätsklinikum Jena";"NL;DE;AT;CH;SE;LU";;1;0;1;1;0;0 209418;754387;UPtoPARIS;SIGNED;H2020-EU.1.3.4.;MSCA-COFUND-2016;H2020;PhD Programme of Advanced Research in Interdisciplinary Science at ESPCI Paris;2018-01-01;2022-12-31;;"Loyal to its tradition in education and training on an interdisciplinary level between physics, chemistry and biology, ESPCI proposes a brand new international doctoral programme – UPtoPARIS. PhD fellows will have the opportunity to explore a unique environment comprising an elite engineer school, 9 joint research units and a new incubator on campus hosting 12 technology-driven start-ups – a recipe for a cutting-edge doctoral training in the heart of Paris. UPtoPARIS is designed to propose a combination of research activities and innovative and competitive supervising, mentoring and career planning. With PhD projects strongly connected to the transferability of basic science, the programme aims to shape new profiles of forward-looking young researchers by giving them knowledge and skills directly linked to the needs of the European and international industry and market. The intersectoral exposure, provided by secondments, workshops and specific guidance, will help young researchers to gain a precious experience in terms of technological development and application through consciously selected topics of European interest, inspired by the KETs, identified by the EU. The 5 Education and Research Chairs of ESPCI (Total, Michelin, Saint-Gobain, Axa and Safran) are also a guarantee for the privileged long-term partnerships with the industry. The 30 incoming excellent doctoral candidates will also reinforce the internationally renowned profile of ESPCI and the region, by increasing the number of foreign PhD students and, consequently, the quality and the diversity of the scientific exchange. The UPtoParis programme will be a pilot project in terms of better recruitment and career guidance procedures with an important impact on the development of high-quality human resources not only on a local level, but also in the European Research Area.";4708800;2354400;H2020-MSCA-COFUND-2016;/MSCA-COFUND-DP;ECOLE SUPERIEURE DE PHYSIQUE ET DECHIMIE INDUSTRIELLES DE LA VILLE DEPARIS;FR;;;;1;0;1;1;0;0 214506;791804;DetEdIn;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Micro-, Meso-, and Macro-Level Determinants of Educational Inequalities: An Interdisciplinary Approach;2018-10-01;2020-09-30;;Governments across the world recognize the right of the child to education on the basis of equal opportunity. Education shall allow children to develop their talents, abilities, and personality, and the principle of equal opportunity shall guarantee the eradication of any kind of discrimination. Accordingly, in a meritocratic system, educational outcomes should be directly related to individual merit. However, research shows that ascriptive (‘non-merit’) characteristics such as social origin also play a role in shaping educational outcomes. For instance, across OECD countries, no more than one out of five students from families with a low educational background attains a degree in tertiary education, as opposed to two thirds of students from families with at least one parent with tertiary education. These disparities are often considered as a measure of inequality of opportunity and therefore deserve attention from both scientists and policymakers. To date, despite an increasing body of knowledge on educational inequalities, only very little research exists on additive and interactive effects of micro-, meso-, and macro-level characteristics on educational inequalities. Against this background, the proposed research project shall use an interdisciplinary analytic framework to assess how micro-level psychological characteristics (e.g., self-efficacy and motivation), meso-level (family and school) characteristics, and macro-level characteristics (educational policies and wider societal contexts) affect social inequalities in education, and whether their distinct combinations shape inequalities. Data will be derived from standardized cross-national surveys (PISA, TIMSS) as well as from longitudinal cohort studies (e.g., BCS70, MCS, YDS). A variety of state-of-the-art research methods will be employed, including multilevel analysis and growth curve modeling, to generate scientific evidence and extend theory on major determinants of social disparities in education.;171792,6;171792,6;H2020-MSCA-IF-2017;/MSCA-IF-GF;UNIVERSITY COLLEGE LONDON;UK;;;;1;0;1;1;0;0 212702;756575;CoopCat;SIGNED;H2020-EU.1.1.;ERC-2017-STG;H2020;Cooperative Catalysis: Using Interdisciplinary Chemical Systems to Develop New Cooperative Catalysts;2018-02-01;2023-01-31;;"Catalysis, a multidisciplinary science at the heart of many industrial processes, is crucial to deliver future growth and minimize anthropogenic environmental impact, thus being critical to our quality of life. Thus, the development and fundamental understanding of innovative new catalyst systems has clear, direct and long-term benefits to the chemical manufacturing sector and to the broader knowledge-based economy. In this ERC project I will develop novel innovative cooperative catalysts using interdisciplinary chemical systems based on main group elements, transition metals and molecular clusters to achieve better efficiency and improve chemical scope and sustainability of key chemical transformations. This will be achieved through 3 complementary and original strategies based on catalytic cooperation: (i) Transition-Metal Frustrated Lewis Pairs (TM-FLPs); (ii) hybrid systems combining low-valent heavier main group elements with transition metals (Hybrid TM/MGs); and (iii) intercluster compounds (ICCs) as versatile heterogeneized materials for Green Catalysis. These systems, of high synthetic feasibility, combine fundamental concepts from independent areas, e.g. FLPs and low-valent heavier main group elements with transition metal chemistry, and homogeneous with heterogeneous catalysis. The overall approach will be pivotal in discovering novel reactions that rely on the activation of otherwise unreactive substrates. The experience and knowledge gained from (i)-(iii) will be used to inform the design of a second generation of ICC materials in which at least one of the nanoscale bricks is based on polymetallic TM-FLPs or Hybrid TM/MG systems. Delivering ground-breaking new fundamental science, this pioneering project will lay the foundation for future broad ranging benefits to a number of EU priority areas dependant on innovations in catalysis: innovative and sustainable future energy systems, solar technologies, sustainable chemistry, manufacturing, and healthcare.";1445000;1445000;ERC-2017-STG;/ERC-STG;AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS;ES;;;;1;0;1;1;0;0 196374;666010;TOPMed10;SIGNED;H2020-EU.1.3.4.;MSCA-COFUND-2014-FP;H2020;Fellowship Programme supporting Career Development and Interdisciplinary Training in Omics driven Personalised Medicine;2015-07-01;2020-06-30;;UCD proposes the implementation of a new postdoctoral fellowship programme supporting career development and interdisciplinary training in omics driven Personalised Medicine for 10 high calibre experienced researchers undertaking transnational ‘incoming’ mobility to Ireland (TOPMed10). Experienced researchers, by definition under Marie Sklodowska-Curie Actions (MSCA), are those in possession of a doctoral degree (or at least 4 years of research experience (FTE)) at the time of the deadline for the submission of their fellowship proposal. TOPMed10 offers 10 prestigious fellowships, 2-3 years in duration, across two calls. Fellowships will be offered at 2 levels: level 1 will be targeted at incoming experienced researchers (as per MSCA definition) with 0-3 years additional research experience and level 2 will be targeted at incoming experienced researchers (as per MSCA definition) with 3\ years additional research experience. Career breaks will be taken into account. Fellowships of level 1 and 2 are open to candidates of any nationality who, at the time of the deadline for submission of proposals, shall not have resided or carried out their main activity (work, studies, etc.) in Ireland for more than 12 months in the 3 years immediately prior to the deadline for submission date. Compulsory national service and/or short stays such as holidays are not taken into account. Fellowships will be based in the UCD Research Institutes (Systems Biology Ireland, UCD Charles Institute of Dermatology, UCD Conway Institute of Biomolecular and Biomedical Research and the UCD Clinical Research Centre). Fellows may undertake an optional 3-9 month secondment to a Partner Organisation (incl. academic, industry, clinical sector) or a research performing organisation in any country in the world deemed to be appropriate in terms of meeting the needs of the fellows’ research, training and career development requirements.;1770000;885000;H2020-MSCA-COFUND-2014;/MSCA-COFUND-FP;UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN;IE;;;;1;0;1;1;0;0 206999;721567;CAPICE;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2016;H2020;Childhood and Adolescence Psychopathology: unravelling the complex etiology by a large Interdisciplinary Collaboration in Europe;2017-02-01;2021-01-31;;"In the Roadmap for Mental Health and Wellbeing Research in Europe (ROAMER), top-priority is research into child and adolescent mental health symptoms. CAPICE (Childhood and Adolescence Psychopathology: unravelling the complex etiology by a large Interdisciplinary Collaboration in Europe) will address this priority. This network will elaborate on the EArly Genetics and Lifecourse Epidemiology (EAGLE) consortium, a well-established collaboration of the many European birth and adolescent population based (twin and family) cohorts with unique longitudinal information on lifestyle, family environment, health, and emotional and behavioral problems. Phenotypic and genome-wide genotypic data are available for over 60,000 children, in addition to genome-wide genotypes for over 20,000 mothers and epigenome-wide data for over 6,000 children. Combined with the enormous progress in methodology, the results of the research performed in this network will greatly expand our knowledge regarding the etiology of mental health symptoms in children and adolescents and shed light on possible targets for prevention and intervention, e.g. by drug target validation. Moreover, it will provide Early Stage Researchers (ESRs) with an excellent training in the psychiatric genomics field given by a multidisciplinary team of eminent scientists from the academic and non-academic sector highly experienced in e.g., gene-environment interaction and covariation analyses, (epi)genome-wide association studies, Mendelian Randomization (MR) and polygenic analyses. With a focus on common and debilitating problems in childhood and adolescence, including depression, anxiety and Attention Deficit Hyperactivity Disorder, CAPICE will contribute to improving later outcomes of young people in European countries with child and adolescent psychopathology.";3163687,92;3163687,92;H2020-MSCA-ITN-2016;/MSCA-ITN-ETN;STICHTING VU;NL;"IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE;UNIVERSITEIT TWENTE;UNIVERSITA DEGLI STUDI DI CAGLIARI;JANSSEN-CILAG AKTIEBOLAG;KAROLINSKA INSTITUTET;UNIVERSITY OF BRISTOL;ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM;GOETEBORGS UNIVERSITET;KING'S COLLEGE LONDON";"UK;NL;IT;SE";;1;0;1;1;0;0 201674;711859;NaMeS;SIGNED;H2020-EU.1.3.4.;MSCA-COFUND-2015-DP;H2020;“Interdisciplinary NAnoscience School: from phenoMEnology to applicationS”;2016-11-01;2021-10-31;;"The Project “Interdisciplinary NAnoscience School: from phenoMEnology to applicationS” (‘NaMeS’) is aimed at creating a new generation of scientists, capable of working in both scientific and business sectors, and becoming the stimulants and intermediaries of knowledge & technology transfer on an international scale. NaMeS combines chemistry, physics, mathematics, biology and material science. The Project, benefiting from former IPC achievements in nanoscience, was designed to employ the phenomenological knowledge concerning nanoscale processes to the creation of new materials applicable in industrial technology, medical diagnostics and environmental protection (in line with regional and national SMART specializations). NaMeS includes 22 separate PhD research proposals, embedded in the state-of-the-art basic science, reaching beyond academic sector and having good prospects for commercialization. These will be supervised by highly qualified and experienced IPC scientists, often the authors of patents. Additionally, every ESR will be co-supervised by an excellent scientist from an adequate foreign research institution. In the course of NaMeS, ESRs will be seconded to these partner institutions to gain new knowledge, skills, contacts, and experience coming from working in an international environment. The Project will run in parallel to the existing IPC doctoral school. It will partly benefit from its structure, with essential modifications in research and educational programmes, securing the required international and inter-sectoral flows. In particular, NaMeS will include a collection of specialized lectures, dealing with various aspects of nanoscience – theoretical, experimental, and application-oriented – delivered by internationally recognized experts. It will also be enriched by internships, assuring the cross-fertilization between different disciplines, and by the courses on transferable skills.";4604160;2302080;H2020-MSCA-COFUND-2015;/MSCA-COFUND-DP;INSTYTUT CHEMII FIZYCZNEJ POLSKIEJ AKADEMII NAUK;PL;;;;1;0;1;1;0;0 210603;754432;ImPRESS;SIGNED;H2020-EU.1.3.4.;MSCA-COFUND-2016;H2020;International Interdisciplinary PhD studies in Biomedical Research and Biostatistics. Supporting the career and training in omic-based research and biostatistics by inter-national and-sectoral mobility;2018-02-01;2023-01-31;;The aim of the project is to launch Interdisciplinary PhD Studies in Biomedicine aimed at young aspiring scientists, who will conduct research on life-style diseases and on biostatistics and bioinformatics methods necessary to process and interpret data obtained in research projects. The studies will provide an outstanding opportunity for in-depth education in high-throughput experimental and computational techniques used in genomics, proteomics, metabolomics and immunology. 15 PhD students will be involved in scientific projects supervised by excellent researchers, outstanding scientists selected from partner organizations, with a profound expertise and experience in: Cancer/Mutagenesis, Cardiovascular diseases, Population Medicine and Epidemiology, Diabetes/Obesity, Metabolic and Neurodegenerative diseases, Regenerative medicine, Molecular Biology, Genomics, Protein Analysis and Proteomics, Metabolomics/Lipidomics, Immunology and Experimental Medicine. They will be employed at Medical University of Bialystok. The development of doctoral students' research potential will be based also on internships, short research visits, conferences and trainings at the partner institutions: CEMBIO San Pablo University, Vienna Biocenter, Spanish National Center for Cardiovascular Research CNIC, Bialystok University of Technology and CenStat at Hasselt University. Industry partner organizations: Agilent Technology, deCODE, ideas4biology and Warsaw Genomics will invite PhD students for scientific visits, to familiarize young researchers with the tools and methods of work and organizational environment in the company. Industry providing their know-how will educate, and prepare their potential employees with high qualifications to get job in the close future. Best young scientists from the beginning of their academic career will be able to gain scientific independence and will have huge motivation to become more involved and creative in the research projects carried out thanks to COFUNDing the project by EC.;3139200;1569600;H2020-MSCA-COFUND-2016;/MSCA-COFUND-DP;UNIWERSYTET MEDYCZNY W BIALYMSTOKU;PL;;;;1;0;1;1;0;0 216361;810425;MOSaIC;SIGNED;H2020-EU.4.c.;WIDESPREAD-03-2017;H2020;Molecular Signaling in Health and Disease - Interdisciplinary Centre of Excellence;2018-11-01;2023-10-31;;"The International Institute of Molecular and Cell Biology (IIMCB) is included among the best Polish research institutes in the life sciences and has the highest score in national evaluations to date. With modern organizational patterns, excellent staff, state-of-the-art equipment, and an international work environment, IIMCB is positioned to achieve a level of excellence tantamount to the best European entities. To realize this goal, we created the Interdisciplinary Centre of Excellence in Molecular Signalling in Health and Disease (MOSaIC). The ERA Chairs scheme gives us a unique opportunity to improve our performance by attracting an outstanding principal investigator in molecular signalling. This investigator will complement and strengthen the current research lines at IIMCB and will influence structural changes for responsible research and effective science management. The MOSaIC has 5 objectives. The first is recruitment of an ERA Chair holder and affiliates in an open process that involves a set of incentives for the successful candidate to establish an excellent research group. The second is to augment scientific research and innovation in IIMCB and surrounding region through the work of the ERA Chair holder in molecular signalling, a field with great promise for medical advancement. The third and fourth involve structural improvements in science management and consolidated HR activities to develop a research environment that meets the highest international standards, including those set in the EU Charter and Code. Dissemination and communication activities will enable us to achieve the fifth objective: widespread recognition of the MOSaIC and IIMCB among national and European stakeholders. Thanks to the MOSaIC, IIMCB scientists will lead innovative and internationally competitive research in an environment of excellent organizational standards and support. They will engage in European partnerships, and their projects will lead to practical inventions.";2498887,5;2498887,5;H2020-WIDESPREAD-03-2017-ERAChairs;/CSA;INTERNATIONAL INSTITUTE OF MOLECULAR AND CELL BIOLOGY;PL;;;;1;0;1;1;0;0 202723;701230;DivMeanBody;CLOSED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Divergent Meanings: understanding the postmortem fate of human bodies found in Neolithic settlements from the Balkan area in light of interdisciplinary data;2016-10-01;2018-09-30;;"This research proposal is designed as an exploration in the construction of the prehistoric body and identity, by studying the post-mortem fate of human remains discovered in Neolithic settlements in the Balkan area (between 7th-5th millennia BC). These settlements have yielded collections of disarticulated/fragmentary/scattered human remains. Traditionally such human remains have been either a focus of osteological studies, looking at them in a biological dimension, or subjected to cultural analysis. DivMeanBody aims at taking a multi-disciplinary comparative perspective, at the cross-road of archaeology and osteology, towards the re-interpretation of such deposits from a taphanomic perspective to answer the question of whether these are deliberate depositions or more complex, including non-cultural processes, might explain this fragmentation. The beginnings of settlements, agriculture and the Neolithic way of life are marked by such funerary practices, and studying them is integral to understanding past ways of life and cultures. Through its aims, DivMeanBody will help us better understand how these past people were performing and dealing with the dynamic processes of life and death in their communities and the relation of these practices to the formation of archaeological deposits. In the same time, it will surpass the divide present in contemporary research between a biological body (studied by osteology) and a cultural body (by archaeology). The results of DivMeanBody will bring an original contribution that can challenge contemporary distinctions between domestic-funerary space, whole bodies-fragmentary parts, the world of the living-the realm of the dead. It will also create links between categories of archaeological material which are otherwise interpreted separately and thus offer new insights into what being human meant in the past.";183454,8;183454,8;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;UK;;;;1;0;1;0;0;0 206517;734434;DRYNET;SIGNED;H2020-EU.1.3.3.;MSCA-RISE-2016;H2020;Setting an interdisciplinary/sectorial/international research network to explore dry storage as an alternative strategy for cells/germplasm biobanking;2017-03-01;2021-02-28;;The number of biobanks for diagnostic/clinical/biodiversity preservation purposes is increasing exponentially, representing an economic burden for the EU. Cryopreservation (Liquid Nitrogen LN) is the only cells/gametes long-term repository method. LN storage is expensive though, requires dedicated facilities, is hazardous, carries pathogens and has high carbon footprint. DRYNET objective is to set an inter-sectorial/multidisciplinary/international network between EU academic (5), SME (3), the EU pan-Biobank, and international partners (Japan/Thailand), with the aim of sharing knowhow & expertise to lay down the theoretical and early empirical basis for the dry storage of cells/germplasm. DRYNET merges the partner’s expertise, theoretical/ biophysical/ mathematical modelling, cellular/ molecular/ insect biology, embryology, mechanical engineering into a coherent approach towards dry storage of cells/germplasm. International/inter-sectorial secondments, with meeting/workshop/summer school will be primary tools to implement our strategy for biobanking. Outreaching activities will guarantee public awareness of the project. DRYNET’s relies on water subtraction to induce a reversible block of metabolism, a survival strategy available in nature (anhydrobiosis). The work plan foresees the exploitation of natural xero-protectants (Late Embryogenesis Abundant proteins), loaded/expressed in gametes/cells, before drying. The best drying approaches, supported by theoretical/biophysical/math modelling, will be implemented by SMEs/academy partners. DRYNET will bring a simplification of currents practices, with cost and carbon footprint reduction, for the maintenance/shipping of biobanks. DRYNET will generate young scientists with transferable skills, ensuring career prospect in academia/industry. DRYNET strengthens the international/sectorial network between different disciplines, ensures long-term sustainability of the project, and boosts European competitiveness in biobanking.;841500;765000;H2020-MSCA-RISE-2016;/MSCA-RISE;UNIVERSITA DEGLI STUDI DI TERAMO;IT;"BIOBANKS AND BIOMOLECULAR RESOURCESRESEARCH INFRASTRUCTURE CONSORTIUM(BBMRI-ERIC);AVANTEA srl;BIOTALENTUM TUDASFEJLESZTO KFT;UNIVERSIDAD DE BURGOS;UNIVERSITA DEGLI STUDI DI CAGLIARI;IMAGENE;UNIVERSITA DEGLI STUDI DI MODENA E REGGIO EMILIA";"AT;IT;HU;ES;FR";;1;0;1;0;0;0 217494;796197;Governmigration;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Governing irregular immigration through detention: discourses and practices from an interdisciplinary approach;2018-10-01;2021-09-30;;Western countries have significant concerns about the increasing number of undocumented migrants and asylum seekers crossing international borders. The European Agenda for Migration includes a set of priorities that address this complex and nuanced problem. Core values of European societies, such as solidarity and human rights, are being tested by irregular migration pressure and the related difficulties of immigration detention. The escalating number of detainees released into host communities instead of being deported has raised new questions about how this population is being managed. This project uses two case studies: Spain and Canada to analyze how the governance of irregular migrants and asylum seekers occurs in two complementary ways. First, at the level of discourse, this research will assess how irregular migration has been represented in the political process by focusing on how immigration detention has emerged as a response to this issue. Second, the project will examine the impact of detention in those released and supervised in the community. This study will also focus on how different actors participant in the governance of migrants and how gender, race and nationality influence this process. Theoretically, this research builds on the governmentality and border control scholarship. Policy analysis and interviews are the primary methods of data collection. This study builds on existing scholarship and will provide a comprehensive and comparative analysis of irregular immigration and detention that can inform various types of immigration policy. The research project will be structured to ensure the applicant receives a high quality and comprehensive training program that includes academic milestones and the management, communication and dissemination competences. This study project is built on the collaboration of several institutions and academics to guarantee the international relevance of the project and the academic excellence of the researcher.;242683,2;242683,2;H2020-MSCA-IF-2017;/MSCA-IF-GF;UNIVERSIDADE DA CORUNA;ES;;;;1;0;1;0;0;0 222395;843239;3D NKCC1;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Interdisciplinary approach to characterize the structure and the ion transport mechanism of NKCC1, a key target for brain disorders.;2019-05-01;2021-04-30;;Neurodevelopmental disorders affect millions of children in Europe and worldwide. A large body of literature indicates that inhibitory GABAergic transmission thorough Cl-permeable GABAA receptors is defective in many of these disorders. However, effective pharmaceutical treatments are still needed. There is increasing scientific evidence that varying the intracellular Cl concentration is one of the more physiological and effective ways to modulate GABAAergic transmission. This concentration is mainly established by the Cl importer NKCC1 and the Cl exporter KCC2. Importantly, the NKCC1/KCC2 ratio is defective in several brain disorders. Moreover, NKCC1 inhibition by the FDA-approved diuretic bumetanide rescues many symptoms in animal models. These findings have already led to clinical studies of bumetanide to treat a broad range of brain disorders. However, this requires chronic treatment, which poses serious issues for drug compliance, given the diuretic effect of bumetanide caused by the inhibition of the kidney-specific Cl transporter NKCC2. Crucially, these issues could be solved by selective NKCC1 inhibitors, which would have no diuretic effect. Yet there is still very little knowledge of the structure-function relationship of NKCC1 in terms of ion transportation and how bumetanide acts on NKCC1. The main goal of this fellowship is to resolve NKCC1’s structure using X-Ray crystallography and/or cryo-electron microscopy. This effort will be coupled to the functional characterization of NKCC1 using in vitro and in silico approaches. The fellow will thus integrate her research skills with key expertise in the structural and molecular biology of ion transporters, allowing her to grow into an independent group leader. Ultimately, this project will provide unprecedented insights into the structure-function relationships of NKCC1 in terms of ion transportation. This will critically accelerate the discovery of new and urgently needed drugs for brain disorders.;168369,6;168369,6;H2020-MSCA-IF-2018;/MSCA-IF-GF;FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA;IT;;;;1;0;1;0;0;0 211889;765298;MOTION;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2017;H2020;Mobile Technology for Infant Social-Cognitive Neuroscience: Interdisciplinary Training Networkfor Innovative Infancy Research;2018-01-01;2021-12-31;;"'Recent international reports emphasize that the first three years of children’s life have more impact on their future outcomes than any other period during life. It is therefore essential that we have a thorough understanding of early social and cognitive development. In the past, experimental research that has fed our knowledge on early development studied infants within restricted, artificial laboratory contexts. However, only by studying children who are actively engaging in natural interaction with their social and physical environment, we can acquire ecologically valid, robust information about their social and cognitive development. It is thus essential to move experimental infancy research towards more natural situations. In doing so, MOTION will train a new generation of highly-skilled experts in the field of early development. New advances in wearable and wireless technologies now provide us with a unique opportunity. We are able to literally 'unleash' the children we study – to free them from cables and constraints associated with the previous research methods. The primary scientific aim of the MOTION project thus is to leverage these new technological advances to study infants’ and toddlers’ body movements, gaze direction, and brain activity as they spontaneously and actively explore the world around them. MOTION will develop, produce and commercialize new tools to study early development in close cooperation between industry and academic partners. Innovative research tools will be used to investigate infants in natural interaction with their social and physical environment and gain a deeper understanding of early development. In addition to disseminating the new tools and research findings among the scientific community, it is the explicit aim of MOTION to reach out to professionals and the public, educate them about early development and instigate an open dialogue between professionals working with young children and developmental researchers.'";3685408,56;3685408,56;H2020-MSCA-ITN-2017;/MSCA-ITN-ETN;STICHTING KATHOLIEKE UNIVERSITEIT;NL;"QUALISYS AB;TWENTE MEDICAL SYSTEMS INTERNATIONAL B.V.;UPPSALA UNIVERSITET;SMART EYE AKTIEBOLAG;BIRKBECK COLLEGE - UNIVERSITY OF LONDON;UNIVERSITY OF LANCASTER ROYAL CHARTER;UNIVERSITA' DEGLI STUDI DI MILANO-BICOCCA;ARTINIS MEDICAL SYSTEMS BV";"SE;NL;UK;IT";;1;0;1;0;0;0 212464;777822;GHAIA;SIGNED;H2020-EU.1.3.3.;MSCA-RISE-2017;H2020;Geometric and Harmonic Analysis with Interdisciplinary Applications;2017-11-01;2021-10-31;;"GHAIA will promote excellence through mobility to the world leader Universities in pure and applied mathematical research: Princeton University, Mit, Yale, Johns Hopkins, the Universities of California, of Texas, of Houston, of Pittsburgh, the Washington University (St. Louis), and the Worchester Polytechnical Institute, the Academia Sinica, the University of Buenos Aires have joined the consortium. European researchers will have the extraordinary opportunity to work in their exciting environment as well as receiving visiting researchers from south America. Moreover two selected enterprises have joined the consortium, allowing intersectorial mobility: Marposs and GMV, leaders in the strategic sectors of EU industry of precision equipments for automatic inspection, and of satellite navigation. Emerging technological problems call for the development of a new integrated framework of geometric and harmonic analysis, which unify in an original picture problems strongly influenced by symmetries and coming from different mathematical and technological fields. The exploitation of groups and supergroups invariances is one of the central goals of harmonic analysis, and nonlocal or nonlinear PDE in group setting present new and unexpected properties. Achievements in these directions are strictly related to a good geometric analysis of the ambient space. With these instruments we will be able to contribute to some of the biggest challenges of this century: data analysis and models of brain functionality. The final goal will be to obtain new geometrical instruments of machine vision, to be applied to develop new products for measurement of industrial processes and for satellite guidance. The international collaborations, through research and secondments, with the extraordinary selected third countries institutions of the consortium, will provide very high level transfer of knowledge and will have a strong impact on the research capability of the EU sending institutions.";1930500;1782000;H2020-MSCA-RISE-2017;/MSCA-RISE;ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA;IT;"UNIVERSIDAD DE GRANADA;UNIVERSITE PARIS-SUD;Marposs SpA;UNIVERSIDAD AUTONOMA DE MADRID;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;GMV AEROSPACE AND DEFENCE SA";"ES;FR;IT";;1;0;1;0;0;0 198114;676265;INDUCT;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2015-ETN;H2020;Interdisciplinary Network for Dementia Utilising Current Technology (INDUCT);2016-03-01;2020-02-29;;"Dementia raises complex challenges for people with dementia, their families, and society. The European Parliament has called for investment in high quality, innovative technology research to improve dementia care but so far there has been little benefit because research has generally been limited, small scale and methodologically flawed. In particular: the poor understanding between research and business of how people with dementia use technology means new applications are designed without an in-depth appreciation of people’s needs, preferences and limitations; there is little knowledge about practical, psychological and social barriers and facilitators to implementation making it hard to get results into practice; there is a serious shortage of research trained professionals who combine expertise on dementia care research and technology. In conjunction with INTERDEM the world’s largest network of psychosocial research for people with dementia this ITN will: develop a European multi-disciplinary, intersectoral educational research framework for Europe, to comprehensively train 15 early stage researchers (ESRs) to PhD level; provide the research evidence to show how technology may improve care and quality of life for people with dementia; and provide the European workforce with a much needed new generation of excellent research trained professionals. The objectives of INDUCT are to: determine practical, cognitive & social factors to improve usability of technology; evaluate the effectiveness of specific contemporary technology; trace facilitators & barriers for implementation of technology in dementia care. Using advanced methods in applied health research (e.g. randomised controlled trials, qualitative studies) INDUCT will provide the evidence needed to demonstrate how to make dementia care technology more usable, more effective, and better implemented in practice, culminating in an international consensus guideline for improving policy and practice.";3878757;3878757;H2020-MSCA-ITN-2015;/MSCA-ITN-ETN;THE UNIVERSITY OF NOTTINGHAM;UK;"STICHTING VU;VRIJE UNIVERSITEIT BRUSSEL;UNIVERSITEIT MAASTRICHT;STICHTING VUMC;I MAS D Y EMPLEO SERVICONSULTING SL;KAROLINSKA INSTITUTET;UNIVERZITA KARLOVA;UNIVERSITY COLLEGE LONDON";"NL;BE;ES;SE;CZ;UK";;1;0;1;0;0;0 198274;675121;VI-SEEM;SIGNED;H2020-EU.1.4.1.3.;EINFRA-9-2015;H2020;VRE for regional Interdisciplinary communities in Southeast Europe and the Eastern Mediterranean;2015-10-01;2018-09-30;;"In the last decade, a number of initiatives were crucial for enabling high-quality research - by providing e-Infrastructure resources, application support and training - in both South East Europe (SEE) and Eastern Mediterranean (EM). They helped reduce the digital divide and brain drain in Europe, by ensuring access to regional e-Infrastructures to new member states, states on path to ascension, and states in European Neighborhood Policy area – in total 14 countries in SEE and 6 in EM. This VI-SEEM proposal brings together these e-Infrastructures to build capacity and better utilize synergies, for an improved service provision within a unified Virtual Research Environment (VRE) for the inter-disciplinary scientific user communities in the combined SEE and EM regions (SEEM). The overall objective is to provide user-friendly integrated e-Infrastructure platform for regional cross-border Scientific Communities in Climatology, Life Sciences, and Cultural Heritage for the SEEM region; by linking compute, data, and visualization resources, as well as services, models, software and tools. This VRE will provide the scientists and researchers with the support in full lifecycle of collaborative research: accessing and sharing relevant research data, using it with provided codes and tools to carry out new experiments and simulations on large-scale e-Infrastructures, and producing new knowledge and data - which can be stored and shared in the same VRE. Climatology and Life Science communities are directly relevant for Societal Challenges. The driving ambition of this proposal is to maintain leadership in enabling e-Infrastructure based research and innovation in the region for the 3 strategic regional user communities: supporting multidisciplinary solutions, advancing their research, and bridging the development gap with the rest of Europe. The VI-SEEM consortium brings together e-Infrastructure operators and Scientific Communities in a common endeavor.";3300000;3300000;H2020-EINFRA-2015-1;/RIA;ETHNIKO DIKTYO EREVNAS TECHNOLOGIAS AE;EL;"MACHBA - INTERUNIVERSITY COMPUTATION CENTER;RESEARCH AND EDUCATIONAL NETWORKING ASSOCIATION OF MOLDOVA;SYNCHROTRON-LIGHT FOR EXPERIMENTAL SCIENCE AND APPLICATIONS IN THE MIDDLE EAST;BIBLIOTHECA ALEXANDRINA*LIBRARY OFALEXANDRIA BIBALEX;KORMANYZATI INFORMATIKAI FEJLESZTESI UGYNOKSEG;INSTITUTE OF INFORMATION AND COMMUNICATION TECHNOLOGIES;UNIVERZITET U BANJOJ LUCI;INSTITUTE FOR INFORMATICS AND AUTOMATION PROBLEMS OF THE NATIONAL ACADEMY OF SCIENCES OF THE REPUBLIC OF ARMENIA;INSTITUT ZA FIZIKU;NEMZETI INFORMACIOS INFRASTRUKTURA FEJLESZTESI IRODA;GEORGIAN RESEARCH AND EDUCATIONAL NETWORKING ASSOCIATION;UNIVERSITATEA DE VEST DIN TIMISOARA;THE CYPRUS INSTITUTE;JAVNA USTANOVA UNIVERZITET CRNE GORE PODGORICA;Ss. CYRIL AND METHODIUS UNIVERSITY IN SKOPJE;UNIVERSITETI POLITEKNIK I TIRANES";"IL;MD;JO;EG;HU;BG;BA;AM;RS;GE;RO;CY;ME;MK;AL";;1;0;1;0;0;0 211562;765860;AQUAlity;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2017;H2020;Interdisciplinar cross-sectoral approach to effectively address the removal of contaminants of emerging concern from water;2017-10-01;2021-09-30;;AQUAlity is a multidisciplinary and cross-sectoral European Training Network, that consist in eighteen participants (7 universities, 3 research institutes and 8 companies) and aims to generate and promote highly skilled scientists with the potential to face the present and future challenges concerning the protection of water resources from contaminants of emerging concern (CECs). AQUAlity will enroll fifteen early-stage researchers (ESRs) to conduct cutting-edge research on multidisciplinary aspects of novel hybrid technologies for the removal of CECs from aqueous systems. Moreover, ESRs will be trained to develop their creativity, critical and autonomous thinking, and entrepreneurial skills, thus boosting their scientific skills and innovation capacity in the field of water treatment technologies. This goal will be attained via a structured training-through-research programme, consisting of original individual research projects (performed both at the beneficiary organization and through intersectoral secondments) and education on technical and transferable skills (performed both at local level and with network-wide events). The overall research goal of AQUAlity is to develop highly innovative hybrid green technologies for CECs removal from aqueous systems by unconventional solar advanced oxidation processes (AOP) in combination with high flux ceramic nanofiltration membranes. Hence, ESRs will conduct frontier research in the field of AOP (organic photocatalysis, sensitized photocatalysts, photo-Fenton), materials development, nanofiltration technology, and will develop innovative hybrid photochemical/membranes systems to be tested on different waters to prove their potential for the production of high-quality water. Advanced analytical tools for the determination of CECs, their degradation products and water safeness will be developed. Thanks to the presence of industrial participants, AQUAlity aims for the commercial exploitation of part of the research results.;3897678,24;3897678,24;H2020-MSCA-ITN-2017;/MSCA-ITN-ETN;UNIVERSITA DEGLI STUDI DI TORINO;IT;"ECOLE POLYTECHNIQUE;CENTRO DE INVESTIGACIONES ENERGETICAS, MEDIOAMBIENTALES Y TECNOLOGICAS-CIEMAT;KARADENIZ TEKNIK UNIVERSITESI;UNIVERSITA DEGLI STUDI DEL PIEMONTE ORIENTALE AMEDEO AVOGADRO;UNIVERSITAT POLITECNICA DE VALENCIA;PANEPISTIMIO IOANNINON;Societ? Metropolitana Acque Torino S.p.A.;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;LIQTECH INTERNATIONAL A/S;AALBORG UNIVERSITET";"FR;ES;TR;IT;EL;DK";;1;0;1;0;0;0 199018;692041;TrainMALTA;SIGNED;H2020-EU.4.b.;H2020-TWINN-2015;H2020;Interdisciplinary Training in High-Throughput Sequencing, Bioinformatics and Model Systems: Moving towards Clinical applications of Genomics;2016-01-01;2018-12-31;;"This proposal is designed to expedite capacity building in Malta through training in Bioinformatics for the analysis of High-Throughput Sequencing data (HTS), Epigenomics and Model Systems for the validation of candidates identified by HTS. Falling costs and accessibility to HTS technologies has made it easier for researchers to generate the data. The bottleneck is the data processing, analysis and integration of HTS data generated from different applications (genomics, epigenomics, transcriptomics) and validation of candidate genes and mutations identified through HTS. To this end, this Twinning action will focus on the transfer and exchange of knowledge between expert groups from two internationally-leading research institutions, the University of Cambridge (UCAM) and the Katholieke Universiteit Leuven (KU Leuven), and scientists, postgraduates and academics from the University of Malta (UoM); through varied forms of training such as summer schools, online tutoring and mentoring, training workshops, exchanges and expert visits, networking and collaborations. The specific focus of this action will be to provide training on best-practices in bioinformatic analysis, integration of HTS data (including whole genomes and epigenomes), robust quantitative analytical methods as well as training in the use of model systems: the zebrafish model and induced pluripotent stem cells; iPSCs. These activities will significantly strengthen the knowledge base at UoM; and, by increasing the research profile of the University, help promote the participation of Malta in future EU research programmes. Furthermore, there will also be advancements in science and technology which will benefit regional and European socio-economic development.";999372,5;999372;H2020-TWINN-2015;/CSA;UNIVERSITA TA MALTA;MT;"THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;KATHOLIEKE UNIVERSITEIT LEUVEN";"UK;BE";;1;0;1;0;0;0 193930;642620;INTEGRATE;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2014-ETN;H2020;Interdisciplinary Training Network for Validation of Gram-Negative Antibacterial Targets;2015-01-01;2018-12-31;;Antimicrobial resistance is posing a continuously-rising threat to global health. Indeed, one key recommendation from the recent “Action plan against the rising threats from Antimicrobial Resistance” report (submitted by the Commission to the European Parliament and Council (15.11.2011)) is the development of effective antimicrobials or alternatives for treatment of human and animal infections. The INTEGRATE project is a direct response to this. We have assembled a team of 10 beneficiaries from eight EU member states, encompassing both academic and non-academic sectors and different disciplines, to form a consortium committed to training Early Stage Researchers (ESRs) in the discovery and preclinical validation of novel Gram-negative antibacterial agents and antibacterial targets. The principle aim of the consortium is to provide a training platform where students are exposed to every aspect of the antimicrobial discovery process, ranging from target identification and validation, through organic synthesis, in silico design and compound screening, to mode-of-action and possible resistance mechanisms. This exposure will be accomplished through a concrete secondment plan, coupled with a series of high-level consortium-wide training events and networking programmes. Our intention is to reverse the current fragmentation of approaches towards antibacterial discovery through mutual cooperation. The INTEGRATE training framework is built on an innovative research project aimed at targeting important but non-essential gene products as an effective means of reducing bacterial fitness, thereby facilitating clearance of the pathogen by the host immune system. To achieve this, the individual work programmes have been designed to seamlessly inter-mesh contributions from the fields of in silico design, organic synthesis, molecular biology and biochemistry, and the very latest in vitro and in vivo screening technologies.;2793330,72;2793330,72;H2020-MSCA-ITN-2014;/MSCA-ITN-ETN;UNIVERSITA DEGLI STUDI DI PARMA;IT;"UNIVERSITEIT ANTWERPEN;HELSINGIN YLIOPISTO;THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.;APTUIT (VERONA) SRL;TAROS CHEMICALS GMBH & CO KG;LATVIJAS ORGANISKAS SINTEZES INSTITUTS;ITA-SUOMEN YLIOPISTO;UNIVERZA V LJUBLJANI";"BE;FI;UK;DE;IT;LV;SI";;1;0;1;0;0;0 196121;661555;PAOLInA;CLOSED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Physical Activities of Older Adults: Longitudinal Interdisciplinary Analysis;2016-03-01;2018-04-30;;The PAOLInA-project focuses on physical activities of older citizens of European countries. It begins with the analysis of the phenomenon “physical activities”, and their change in the course of the late and latest years of life. The goal is to show what is covered by the term “physical activities” (PAs), and to differentiate PAs into domains according to their purpose (e.g. sports in leisure time, PA for self-care, PA as form of transportation). The Experienced Researcher (ER) hypothesizes that the overall involvement of older adults in PA does not necessarily decline as the individuals are getting older, but that some types of activities may even increase or replace others. If these interdependencies are neglected in the measurement older adults may appear as more sedentary than they actually are. The ER will also examine the factors that influence the change of the PAs. She will look at the interplay between individual characteristics and the attributes of people’s living environments. As a result, patterns of PA promoting factors will be carved out. The research will be based on secondary analysis of various longitudinal data sets, such as the German Socioeconomic Panel (SOEP) and the Survey of Health and Retirement in Europe (SHARE). Multilevel modelling will be applied in the statistical analyses. Thus, the PAOLInA-project is innovative in several respects: It will differentiate the PAs, which – according to the state of the existing research – has rarely been the case. It will reveal the long-term developments in older adults’ engagement and involvement in PAs. It will match individual characteristics with environmental and regional indicators. The ER will introduce her perspective of health psychology into an institute that does not have this specialization yet. She will benefit from the excellent methodological expertise of her prospective supervisor, additional training and support from the partners, and get access to a European network of collaborators.;159460,8;159460,8;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;HUMBOLDT-UNIVERSITAET ZU BERLIN;DE;;;;1;0;1;0;0;0 197132;665850;INSPIRE;SIGNED;H2020-EU.1.3.4.;MSCA-COFUND-2014-DP;H2020;INterdiSciPlinarity and excellence for doctoral training of International REsearchers in Paris;2015-10-01;2020-09-30;;"United in a Community of Universities and Institutions, called “Université Sorbonne Paris Cité” (USPC), eight research universities and five research organisations located in Paris and its surroundings have decided to join their forces to build a world-class new type of university. Together they form a research-intensive university, with over 12000 professors and researchers including more than 6000 doctoral candidates. Each year, 1100 of these candidates defend their PhD thesis, corresponding to about 10% of the yearly new doctors cohort in France. These graduates are enrolled in one of the 31 doctoral schools affiliated to USPC and covering all fields of knowledge. INSPIRE will give more favourable working conditions to the selected candidates compared to French standards while giving a better visibility. It thus expects to 1. Attract better candidates from a wider range of countries, raising globally the level of selection 2. Provide improved collaboration opportunities at international scale and with the non academic sector 3. Improve follow-up and mentoring conditions, notably through the presence of dedicated personnel. Within the five-year programme, INSPIRE aims to launch two calls to recruit 30 doctoral candidates for each call. They will be welcomed into the doctoral schools of its partner organisations thanks to the EU contribution and the USPC financial support. An independent, international committee will conduct the final selection. The participants will be provided with a three-year work contract for full-time research positions with additional access to dedicated funding for mobility and additional research expenses. All selected candidates will be offered dedicated housing through CROUS , another partner organisation of INSPIRE. Equal opportunity issues will be addressed in all aspects of the programme thanks to the expertise gained by the participation of two USPC members in FP7 projects (TRIGGER at Paris Diderot and EGERA at Sciences Po).";9417600;4708800;H2020-MSCA-COFUND-2014;/MSCA-COFUND-DP;UNIVERSITE PARIS DIDEROT - PARIS 7;FR;;;;1;0;1;0;0;0 208341;744413;VehmeLit;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Legal Cultures and Literary Trials in the Age of Goethe. The Vehmic Court Motif in Interdisciplinary and Comparative Perspective;2018-01-01;2019-12-31;;"The project aims at a first systematic and in-depth investigation of the motif of the Vehmic Court – a medieval secret tribunal – in German literature of the late 18th and early 19th centuries. Despite the remarkable popularity of the subject, little research has yet been conducted to define the epistemological framework of its development. By dismissing the Vehme as a “trivial” trope, scholars have not grasped its broader relevance for the culture of the Saddle Period around 1800, an age of transitions and paradigm shifts in society and politics, but also in literature, historiography and the legal system. Through a close-reading analysis and interpretation of a corpus of around twenty plays and novels on the topic, most of which will be examined for the first time, Dr Vecchiato will clarify the reasons for the flourishing of Vehmic Court fictions in the Age of Goethe. By situating the texts within the cultural and historical horizon in which they were produced, he will shed new light on the interactions between popular and canonical literature, Law and Literature as well as Literature and History in that period. Furthermore, he will explore the cross-cultural dimension of the topic, by studying its reception in British literature. The project is a natural outgrowth of the researcher’s interest in the literature of the Age of Goethe; at the same time it grants him the possibility to acquire new competences and multidisciplinary knowledge, which will be crucial for the development of a broader research on the literary representation of trial scenes in German literature. Besides offering outstanding intellectual exchange and the possibility to establish international collaborations, a MSC-IF at King’s College London will help Dr Vecchiato further enhance his scholarly profile and track record of publications. Through teaching, dissemination and outreach activities, he will be able to reach full professional maturity and to generate impacts in and beyond academia.";183454,8;183454,8;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;KING'S COLLEGE LONDON;UK;;;;1;0;1;0;0;0 200991;701911;DISCOVERING;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-GF;H2020;Interdisciplinary Model of Schooling: Exploring Ethical Culture in International Science Assessments;2016-09-01;2018-08-31;;"Exploring the effect of School Ethical Culture (SEC) on students' science achievements is the goal of this study. The integrative model that I propose demonstrates the impact of both external and internal school factors on the TIMSS 2011 assessments. The originality of this proposal is rooted in three points: (A) The fact that the focus on SEC as a predictor of student achievement in science is currently unnoticed in international assessment studies; (B) No previous study has investigated the differences in SEC among participating countries; and (C) This study focuses on ethical perceptions from the viewpoints of principals, students, and teachers. Addressing the study's objective, I will conduct a multi-international disciplinary study that will draw on data from approximately 45 countries, including much of Europe and others. The study will examine the dimensions of SEC separately for teachers, students, and principals by calculating the factor loadings of the latent SEC for each questionnaire and applying hierarchical linear modelling to estimate the effect of student-, school- and country-level on science achievement. The hope is that the findings will prompt a rethinking of analytical models of schooling and facilitate the design of ethical policies that could narrow achievement gaps. This approach could establish a new research field in education. The proposed study will draw on Prof. Benavot’s supervision (outgoing host, SUNY at Albany), and his close contacts with many European researchers, as well as on Dr. Klein's (supervisor, return host, BIU) expertise in effective learning and national assessments. I see great potential for using this study to establish long-term collaborations with European and American scientists through my experience and contacts with other European researchers. Moreover, this fellowship will deepen my research, facilitating my advancement to the next stage of my academic career.";177319,8;177319,8;H2020-MSCA-IF-2015;/MSCA-IF-GF;BAR ILAN UNIVERSITY;IL;;;;1;0;1;0;0;0 196644;659749;InterAct;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;INTerdisciplinary ACTion for accelerating RD on and implementation of solid sorption heat pumps;2015-07-01;2016-06-30;;"INTERACT: Interdisciplinair action for accelerating R&D on and implementation of solid-sorption heat pumps aims to advance the introduction of solid-sorption heat pumps to the market and to expand their application to industrial process heating as well as heating in buildings. According to the International Energy Agency (IEA), energy efficiency is the first option for reducing carbon dioxide emissions – before renewables and biofuels. Solid-sorption heat pumps are a very promising option for energy efficiency in heating and cooling, which accounts for 50% of our final energy use. Three project objectives have been defined: 1. to develop solid-sorption reactors with a power density exceeding 1 MW/m3; 2. to develop a strategic market plan in cooperation with manufacturers and end-users containing the required technical specifications for solid-sorption heat pumps and an approach to overcome the main non-technological challenges; 3. to maximize impact of this & other related solid-sorption heat pump project results. This work will enhance the research and innovation skills of the applicant, providing him with collaborative international research experience at the highest level and new career perspectives. The collaborative research undertaken is in the overall area of the Rational Use of Energy and Renewable Energy.";97727,4;97727,4;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;THE UNIVERSITY OF WARWICK;UK;;;;1;0;1;0;0;0 204698;677917;ASYFAIR;SIGNED;H2020-EU.1.1.;ERC-StG-2015;H2020;Fair and Consistent Border Controls? A Critical, Multi-methodological and Interdisciplinary Study of Asylum Adjudication in Europe;2016-09-01;2021-08-31;;‘Consistency’ is regularly cited as a desirable attribute of border control, but it has received little critical social scientific attention. This inter-disciplinary project, at the inter-face between critical human geography, border studies and law, will scrutinise the consistency of European asylum adjudication in order to develop richer theoretical understanding of this lynchpin concept. It will move beyond the administrative legal concepts of substantive and procedural consistency by advancing a three-fold conceptualisation of consistency – as everyday practice, discursive deployment of facts and disciplinary technique. In order to generate productive intellectual tension it will also employ an explicitly antagonistic conceptualisation of the relationship between geography and law that views law as seeking to constrain and systematise lived space. The project will employ an innovative combination of methodologies that will produce unique and rich data sets including quantitative analysis, multi-sited legal ethnography, discourse analysis and interviews, and the findings are likely to be of interest both to academic communities like geographers, legal and border scholars and to policy makers and activists working in border control settings. In 2013 the Common European Asylum System (CEAS) was launched to standardise the procedures of asylum determination. But as yet no sustained multi-methodological assessment of the claims of consistency inherent to the CEAS has been carried out. This project offers not only the opportunity to assess progress towards harmonisation of asylum determination processes in Europe, but will also provide a new conceptual framework with which to approach the dilemmas and risks of inconsistency in an area of law fraught with political controversy and uncertainty around the world. Most fundamentally, the project promises to debunk the myths surrounding the possibility of fair and consistent border controls in Europe and elsewhere.;1252067;1252067;ERC-2015-STG;/ERC-STG;THE UNIVERSITY OF EXETER;UK;;;;1;0;1;0;0;0 211395;740426;GeoViSense;SIGNED;H2020-EU.1.1.;ERC-2016-ADG;H2020;GeoViSense: Towards a transdisciplinary human sensor science of human visuo-spatial decision making with geographic information displays;2017-11-01;2022-10-31;;Well-designed mobile, human responsive geographic information technology could improve the lives of millions who daily need to make time critical and societally relevant decisions on the go. However, what are the basic processes with which humans make visuo-spatial decisions when guided by responsive geographic information displays? Visualization research todate has been driven by technical and computational advances to overcome data deluges, but we still have a poor understanding whether, how, and when visual displays support spatio-temporal decision making and action, and for which kinds of users. We will break new ground to overcome this transdisciplinary knowledge gap and aim to: (1) integrate fragmented human-visualization-environment research across the sciences including natural, social/behavioral, and the engineering sciences, all critical to tackle this interdisciplinary problem, (2) develop missing, empirically evaluated design guidelines for human-computer interfaces of current/emerging mobile geographic information technology to support affective, effective, and efficient spatio-temporal decision-making, (3) develop unconventional evaluation methods by critical examination of how perceptual, cognitive, psycho-physiological, and display design factors might influence visuo-spatio-temporal decision making across broad ranges of users and mobile use contexts, and (4) scale up empirical methods from to-date controlled behavioral lab paradigms towards a new in-situ mobile human sensor science. A paradigm shift from current lab-based neuro-cognitive and affective science towards a location-based, close human sensing science will radically change the way we study human behavior across science. In doing so, we can improve spatio-temporal every-day decision making with graphic displays, and facilitate sustainable solutions for the increasingly mobile digital information society having to mitigate environmental emergencies, human refugee crises, or terror attacks.;2500000;2500000;ERC-2016-ADG;/ERC-ADG;UNIVERSITAT ZURICH;CH;;;;1;1;0;1;1;1 205319;682540;TransMID;SIGNED;H2020-EU.1.1.;ERC-CoG-2015;H2020;Translational and Transdisciplinary research in Modeling Infectious Diseases;2016-10-01;2021-09-30;;TransMID focuses on the development of novel methods to estimate key epidemiological parameters from both serological and social contact data, with the aim to significantly expand the range of public health questions that can be adequately addressed using such data. Using new statistical and mathematical theory and newly collected as well as readily available serological and social contact data (mainly from Europe), fundamental mathematical and epidemiological challenges as outlined in the following work packages will be addressed: (a) frequency and density dependent mass action relating potential effective contacts to transmission dynamics in (sub)populations of different sizes with an empirical assessment using readily available contact data, (b) behavioural and temporal variations in contact patterns and their impact on the dynamics of infectious diseases, (c) close contact household networks and the assumption of homogeneous mixing within households, (d) estimating parameters from multivariate and serial cross-sectional serological data taking temporal effects and heterogeneity in acquisition into account in combination with the use of social contact data, and (e) finally the design of sero- and social contact surveys with specific focus on serial cross-sectional surveys. TransMID is transdisciplinary in nature with applications on diseases of major public health interest, such as pertussis, cytomegalovirus and measles. Translational methodology is placed at the heart of TransMID resulting in the development of a unifying methodology for other diseases and settings. The development of a toolbox and accompanying software allow easy and effective application of these fundamentally improved techniques on many infectious diseases and in different geographic contexts, which should maximize TransMID’s impact on public health in Europe and beyond.;1639168;1639168;ERC-2015-CoG;/ERC-COG;UNIVERSITEIT HASSELT;BE;UNIVERSITEIT ANTWERPEN;BE;;0;1;0;0;1;1 211725;764859;POEM;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2017;H2020;PARTICIPATORY MEMORY PRACTICES. Concepts, strategies, and media infrastructures for envisioning socially inclusive potential futures of European Societies through culture;2018-04-01;2022-03-31;;Diverging forces across European societies, most visible in both the contemporary nationalist movements and Islamist radicalization, demand a socially inclusive public memory. Its implementation calls for new strategies, practices, and infrastructures for staging and empowering membership and contribution of people from diverse social and cultural backgrounds for past and future development in Europe. To reach this goal, research needs to develop a comprehensive understanding on concepts, practices, and media infrastructures that facilitate the partaking of people from various backgrounds in the heritage building work of memory institutions (libraries, archives, and museums). The POEM-ETN will provide this comprehensive knowledge by studying in practice theoretical approaches on how connectivities are built by 1) institutions, 2) people and groups, and 3) media infrastructures for a socially inclusive, participatory heritage work and what facilitates or hinders collaboration. Therefore, a new generation of professionals will be trained through an innovative training programme and supervised by peer networks of transdisciplinary knowledge to act as change agents, brokers, and problem solvers in this contested field of heritage work. The comprehensive transdisciplinary composition of the consortium involving universities, memory institutions, civil society organisations, and SMEs from public and private sectors will therefore provide the POEM fellows with transdisciplinary knowledge on cultural and social analysis as well as on transferrable skills with respect to the changing socio-technical, organisational, legal, economic, and ethical issues to address future challenges for participatory memory work.;3406970,52;3406970,52;H2020-MSCA-ITN-2017;/MSCA-ITN-ETN;UNIVERSITAET HAMBURG;DE;"AARHUS UNIVERSITET;TECHNOLOGIKO PANEPISTIMIO KYPROU;ASHOKA UK;UPPSALA UNIVERSITET;STIFTUNG PREUSSISCHER KULTURBESITZ;UNIVERSITY OF GLASGOW";"DK;CY;UK;SE;DE";;0;1;0;0;0;3 201551;707807;HealingFromEnclosure;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Healing from Enclosure: A Political Agroecology of a Science-and-Society Potato Controversy in Belgium;2017-09-01;2019-08-31;;"Against the background of the ongoing crisis of the world’s food systems, this research project investigates how agricultural knowledge shapes, and is shaped by, its broader cultural, economic, socio-technical and socio-ecological context. A transdisciplinary approach –theoretically and empirically explorative, methodologically innovative, and action-oriented—to the production, transmission and application of agricultural knowledge in Belgium, and Europe more broadly, offers a powerful way of thinking about the complex relationships that exist between food systems and agricultural knowledge. Drawing on insights from a variety of disciplinary perspectives –ranging from political ecology, Science, Technology and Society studies, agroecology and ecofeminism—this project seeks to: (a) develop an interdisciplinary and transdisciplinary ‘political agroecology’ framework that broadens and opens up critical discussions on agricultural knowledges; (b) study processes of enclosure and commoning through the study of a science-and-society controversy around the development of genetically engineered potatoes in Belgium to frame agricultural knowledge trajectories; (c) involve ‘concerned groups’ –including farmers, researchers, policy-makers, NGOs and activists— in the development of strategies and actions for social innovation in agricultural knowledge systems. The innovative approach advanced in this research provides a necessary corrective to the prevailing yet partial views of existing approaches to agricultural knowledge systems. By using the lens of ‘political agroecology’, the project engages with the power dynamics inherent in the social interactions which are part of agricultural knowledge, while exploring possibilities for social innovation. The project is hosted at a global, interdisciplinary and policy-committed research centre for sustainability and includes a farmers’ organisation as a non-academic secondment partner to maximise the impact of the IF.";195454,8;195454,8;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;THE UNIVERSITY OF SUSSEX;UK;;;;1;1;0;2;0;2 222482;837498;SONNET;SIGNED;H2020-EU.3.3.6.;LC-SC3-CC-1-2018-2019-2020;H2020;SOCIAL INNOVATION IN ENERGY TRANSITIONS: Co-creating a rich understanding of the diversity, processes, contributions, success and future potentials of social innovation in the energy sector;2019-06-01;2022-05-31;;"SONNET aims to create an inter- and transdisciplinary understanding of the diversity and processes of social innovations in the energy sector (SIE). It assesses - critically and reflexively- the success, contributions and future potential of SIE towards sustainable energy transitions in Europe. SONNET investigates how, to what extent and under which enabling conditions diverse types of SIE may result in new breakthroughs or successfully help to overcome transition barriers; such as limited citizen engagement or slow adoption of new technologies. SONNET’s empirical research is informed by a novel conceptual framework combining insights from sustainability transitions, energy studies and social innovation literatures. It bridges qualitative and quantitative methodological approaches in an innovative multi-method research design. Across 30 qualitative in-depth case studies situated in six European countries, SONNET investigates the diversity, processes, success and contributions of SIE. Given its focus on urban areas as major hubs for SIE, SONNET conducts six transdisciplinary SIE city labs to experiment with new forms of SIE and learn about how multiple actors can harness the potential of SIE. In addition, based on three large-scale representative citizen surveys, SONNET assesses the future potential of SIE and derives implications for reconfiguring existing and developing new business models. SONNET synthesizes its findings in an integrated knowledge framework for a socio-economic, socio-cultural (incl. gender) and socio-political understanding of enabling and impeding conditions for SIE and SIE contributions when working towards accelerating sustainable energy transitions in Europe. Through a cutting edge co-creation, dissemination and exploitation strategy, SONNET ensures that its practical recommendations, tools and capacity building activities have a maximum impact on its key stakeholders such as citizens, SIE actors, policy makers, and businesses.";2999832,5;2999832,5;H2020-LC-SC3-2018-NZE-CC;/RIA;FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.;DE;"STAD ANTWERPEN;MIASTO STOLECZNE WARSZAWA;THE UNIVERSITY OF SUSSEX;STADT MANNHEIM;ETABLISSEMENT D'ENSEIGNEMENT SUPERIEUR CONSULAIRE GRENOBLE ECOLE DE MANAGEMENT;COMMUNE DE GRENOBLE;ICLEI EUROPEAN SECRETARIAT GMBH (ICLEI EUROPASEKRETARIAT GMBH)*;ZURCHER HOCHSCHULE FUR ANGEWANDTE WISSENSCHAFTEN;DUTCH RESEARCH INSTITUTE FOR TRANSITIONS BV;BRISTOL CITY COUNCIL;AKADEMIA LEONA KOZMINSKIEGO";"BE;PL;UK;DE;FR;CH;NL";;0;1;0;0;0;2 206400;730243;NATURVATION;SIGNED;"H2020-EU.3.5.4.2.;H2020-EU.3.5.2.3.;H2020-EU.3.5.1.2.;H2020-EU.3.5.1.3.;H2020-EU.3.5.2.2.";SCC-03-2016;H2020;Nature Based Urban Innovation;2016-11-01;2020-10-31;;"Nature-Based Solutions (NBS) have the potential to respond to climate change, enhance biodiversity and improve environmental quality while contributing to economic regeneration and social well-being. Yet there is a substantial gap between the promise of NBS and their uptake. To unlock the potential of NBS for sustainable urban development, NATURVATION will take a transdisciplinary, internationally comparative approach to: advance assessment approaches (Objective 1) to capture the multiple impacts & values of NBS to deliver a robust evidence base for decision-making; enable innovation (Objective 2) to identify the most promising governance, business/finance and participation models and how to overcome the systemic conditions that currently limit their use to support systemic integration; and generate momentum to realise the potential of NBS through co-design, co-development & co-implementation of new partnerships, knowledge, recommendations, processes and tools required to build capacity, enable replication and foster cultural change (Objective 3). Our transdisciplinary approach working with ‘urban-regional innovation partnerships’ in six different cities and a Task Force of highly respected international organisations working in this arena integrates science, social science and humanities (SSH) and practical expertise and experience to achieve a step-change in the use of NBS for urban sustainability.";7797877,5;7797877,5;H2020-SCC-NBS-1stage-2016;/RIA;UNIVERSITY OF DURHAM;UK;"GEMEENTE UTRECHT;LUNDS UNIVERSITET;MINISTERIE VAN INFRASTRUCTUUR EN WATERSTAAT;KOZEP-EUROPAI EGYETEM;MALMO STAD;SERVEIS DE SUPORT A LA GESTIO SL;NEWCASTLE CITY COUNCIL;MAGYAR TUDOMANYOS AKADEMIA KOZGAZDASAG- ES REGIONALIS TUDOMANYI KUTATOKOZPONT;ICLEI EUROPEAN SECRETARIAT GMBH (ICLEI EUROPASEKRETARIAT GMBH)*;UNIVERSITAT AUTONOMA DE BARCELONA;UNIVERSITEIT UTRECHT;LEIBNIZ-INSTITUT FUR LANDERKUNDE EV;ECOLOGIC INSTITUT gemeinnützige GmbH";"NL;SE;HU;ES;UK;DE";;0;1;0;0;0;2 212969;777707;ReaLsMs;SIGNED;H2020-EU.1.3.3.;MSCA-RISE-2017;H2020;Real Smart City;2017-12-01;2020-11-30;;The overarching objective of the ReaLsMs is to develop and implement a perspective on the Smart City through critical humanities research and innovation in the context of the Digital Studies. The joint research fields of ReaLsMs will be the development of historical and philosophical underpinnings of the Data City and the implementation of the Smart City within local governance structures, including Dublin City Council and Plaine Commune (Paris North). Consisting of a network of three academic partners in the EU, Dublin Institute of Technology - School of Creative Arts, Computer Science and Architecture, (DIT, IE), the Institut de Recherche et d’Innovation (IRI) at the Centre Pompidou (FR) and Durham University, the Centre for Humanities Innovation (DU, UK). The 2 non-academic partners located in the EU are Dublin City Council (DCC, IE) and Plaine Commune (FR). The Third Country academic partners is the Universidad de las Artes in Ecuador (UA, Ecuador). The purpose of developing this consortium as a Marie Sklodowska-Curie Research and Innovation Staff Exchange is to share knowledge across disciplines in order to develop transdisciplinary model for “real smart city,” which is defined as a Smart City that is based on a critical humanities perspective, where citizens are the proper data brokers, engaging through public fora for debate and new technologies that enable citizen participation. Through a international and cross-sectoral network, the aim is to across sectors, allowing academic researchers to work with civic government and data collection while non-academic partners can benefit from the insights of academic partners to create new forms of education that illuminate the “black box” of Smart City technology. The expected outcome of research are a new transdisciplinary epsiteme of the Smart and Data City that is rooted in Digital Studies and subsequently informed methods for handling data collected through Smart City infrastructure.;463500;463500;H2020-MSCA-RISE-2017;/MSCA-RISE;INSTITIUID TEICNEOLAIOCHTA BHAILE ATHA CLIATH;IE;"UNIVERSITY OF DURHAM;COMMUNAUTE D'AGGLOMERATION PLAINE COMMUNE;INSTITUT DE RECHERCHE ET D'INNOVATION;DUBLIN CITY COUNCIL";"UK;FR;IE";;0;1;0;0;0;2 211910;766251;NEUROSOME;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2017;H2020;EXPLORING THE NEUROLOGICAL EXPOSOME;2017-10-01;2021-09-30;;"The main objective of NEUROSOME is to develop an integrative biology-based framework starting from human biomonitoring data to unravel causal associations among the genetic predisposition, cumulative exposure to multiple environmental chemicals and neurological disorders. The project brings together beyond- the-state-of-the-art advances in human biomonitoring and systems biology, exposure monitoring and toxicological testing technologies and advanced tools for computational analyses of the exposure-to-health effect continuum following an exposome paradigm. The NEUROSOME methodology will be applied in population studies across different exposure settings to neurotoxicants (metals and persistent organics) in Europe. This will improve scientific knowledge on cause and-effect relations between environmental stressors and neurodevelopmental disorders taking into account exposure and health effect modification due to intrinsic (e.g. genetic susceptibility) and extrinsic (e.g. diet and socioeconomic status) factors. New standards for human biomonitoring data interpretation in conjunction with environmental and exposure information will be developed for ready use in chemical mixture risk assessment. The training goal is to produce a new generation of exposome researchers, trained in academia, applied research and industry, with transdisciplinary skills (environmental end exposure modelling, human biomonitoring, -omics technologies, high dimensional bioinformatics and environmental epidemiology,) and understanding of fundamental science and its direct application to environmental health challenges. To this aim NEUROSOME will focus on the provision of trans-disciplinary research training to young researchers through a combination of network-wide training programs and individual personalised training-through-research projects to deliver to the EU and the world a new cohort of researchers trained in cutting edge transdisciplinary environmental health sciences";3493845;3493845;H2020-MSCA-ITN-2017;/MSCA-ITN-ETN;ARISTOTELIO PANEPISTIMIO THESSALONIKIS;EL;"UNIVERSITAT ROVIRA I VIRGILI;ZELENA INFRASTRUKTURA DRUSTVO S OGRANICENOM ODGOVORNOSCU ZA ZASTITU OKOLISA I PROSTORNO UREDENJE;ISTITUTO DI RICOVERO E CURA A CARATTERE SCIENTIFICO BURLO GAROFOLO;INSTITUT JOZEF STEFAN;ISTITUTO SUPERIORE DI SANITA;Istituto Universitario di Studi Superiori di Pavia;AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS;KENTRO TOXIKOLOGIAS ANONIMI ETAIRIA SYMVOULEYMKES DIAGNOSTIKES KAI ERGASTIRIAKES YPIRESIES TOXIKOLOGIAS FARMAKOLOGIAS KAI BIOIATRIKIS;UNIVERSITE PARIS DESCARTES";"ES;HR;IT;SI;EL;FR";;0;1;0;0;0;2 205256;722341;ReFocuS;CLOSED;H2020-EU.1.3.5.;MSCA-NIGHT-2016;H2020;The Road to Friday of Science;2016-05-01;2017-12-31;;"'The Road to Friday of Science (ReFocuS) project’s aim is to extensively improve the public attention to science and its importance for society and wellbeing by bringing back the focus of the general public to researchers and the results of their studies. Inspired by the current situation in Europe concerning migrations, we aim to ReFocuS public attention to modern EU concept of: (i) mobility of researchers and ideas, as a basis for economy and social prosperity, and transdisciplinarity of the research, as the essential concept of contemporary research and communication. Moreover ReFocuS aims to refocus: the young minds to be open to functional learning, and to be ready to accept the opportunity to be scientists; the scientists to be approachable because their results are important for not just the academics, but to the society as a whole; and the general audience to be aware of the fact that science is a key to everyday life improvement and progress. The ReFocuS is supported by two main pillars: Night 2016 will be focused on 'Roads', while Night 2017 will be focused on 'People'. 'Roads' is intended to describe the importance of ancient and contemporary routes as a foundation for the modern European science, as well as to understand and respect the effects of migration. 'People' is devoted to mobility of researchers and ideas via ancient roads that affected present variability of people, traditions, social backgrounds, languages, heritage and culture. We will model the migrations influence on today’s society in a scientific way, and show the transdisciplinarity of science to youths and general public. The base of ReFocuS is the encouragement of scientists to stand out and explain the importance of migrations on various levels. The ReFocuS project's major strength is the high mobilization of researchers, and the numerous activities taking place on main busy streets and historical sites of the seven Serbian cities, which will have a high social impact in the region.'";185550;175500;H2020-MSCA-NIGHT-2016;/CSA;INSTITUT ZA BIOLOSKA ISTRAZIVANJA;RS;"CENTAR ZA PROMOCIJU NAUKE;ZAVOD ZA ZASTITU SPOMENIKA KULTURE KRAGUJEVAC;PRIRODNO MATEMATICKI FAKULTET";RS;;0;1;0;0;0;2 199849;687983;MAZI;SIGNED;H2020-EU.2.1.1.;ICT-10-2015;H2020;A DIY networking toolkit for location-based collective awareness;2016-01-01;2018-12-31;;"Do-It-Yourself networking refers to a conceptual approach to the use of low-cost hardware and wireless technology in deploying local communication networks that can operate independently from the Internet, owned and controlled by local actors. MAZI means “together” in Greek and MAZI [http://mazizone.eu] invests in this paradigm of technology-supported networking, as a means to bring closer together those living in physical proximity. Through an experienced interdisciplinary consortium, MAZI delivers a DIY networking toolkit that offers tools and guidelines for the easy deployment and customization of local networks and services. MAZI toolkit is designed to take advantage of particular characteristics of DIY networking: the de facto physical proximity between those connected; the increased privacy and autonomy; and the inclusive access. Such characteristics are used to promote information exchanges that can develop the location-based collective awareness, as a basis for fostering social cohesion, conviviality, knowledge sharing, and sustainable living. To achieve this objective, MAZI brings together partners from different disciplines: computer networks, urban planning and interdisciplinary studies, human-computer interaction, community informatics, and design research. These academic partners will collaborate closely with four community partners to ensure that MAZI toolkit benefits from the grounded experience of citizen engagement. MAZI draws from the diverse mix of competencies of its consortium to develop a transdisciplinary research framework, which will guide a series of long-term pilot studies in a range of environments, and enhanced by cross-fertilization events. The main goal of this process, and measure of success, is establishing DIY networking as a mainstream technology for enabling the development of collective awareness between those in physical proximity, and the development of surrounding research and theorizing of this approach.";1846640;1352890;H2020-ICT-2015;/RIA;PANEPISTIMIO THESSALIAS;EL;"NETHOOD;UNIVERSITAT DER KUNSTE BERLIN;SLACKTIVIST LIMITED;EDINBURGH NAPIER UNIVERSITY;COMMON GROUNDS EV;THE OPEN UNIVERSITY;UNMONASTERY;INURA ZURICH INSTITUT GMBH";"CH;DE;UK";;1;1;0;2;0;1 203185;713694;MULTIPLY;SIGNED;H2020-EU.1.3.4.;MSCA-COFUND-2015-FP;H2020;International Mobility and Training in Photonics Programme;2016-10-01;2021-09-30;;"The aims of the proposed International Mobility and Training in Photonics programme, MULTIPLY, are to facilitate worldwide mobility and offer high-level interdisciplinary and transdisciplinary training for approximately 55 outstanding international researchers (90 fellow*years) commencing their professional development in the area of photonics science, technology and applications. Applicants from any part of the world will be able to participate in this Programme, freely choosing their destinations and research topics. Eligible researchers may apply for one of the following mobility elements: a) incoming to Europe, including Europe-to-Europe mobility; b) outgoing from Europe with re-integration. Prominent scientific standing of the Programme is guaranteed by full backing of a consortium of 46 internationally leading academic partners of worldwide renown. The Partners will maximise MULTIPLY Fellows career development opportunities and assist them in becoming future academic and industrial leaders by offering them cutting edge facilities, excellence in post-doctoral training and mentoring, fast-paced innovation activities and established industrial links, as well as a vibrant, international, and interdisciplinary environments. Massive experience coming from decades of successful fundamental research and industrial applications at Partners domicile in 23 countries form the foundation of the MULTIPLY Programme: non-linear and quantum photonics, integrated and ultra-fast optics and optical engineering, laser science and applications, industrial laser manufacturing, high-speed optical communications, sensing, imaging, optoelectronics, medical applications of photonics, nano-photonics, bio-photonics, and many other areas. Aston Institute of Photonic Technologies (AIPT), Aston University will be managing the MULTIPLY program. The AIPT is one of the largest photonics research centres in the UK with a world-class portfolio of research funding.";6372000;3186000;H2020-MSCA-COFUND-2015;/MSCA-COFUND-FP;ASTON UNIVERSITY;UK;;;;1;1;0;2;0;1 218555;787768;H-Unique;SIGNED;H2020-EU.1.1.;ERC-2017-ADG;H2020;In search of uniqueness - harnessing anatomical hand variation;2019-01-01;2023-12-31;;"H-unique will be the first multimodal automated interrogation of visible hand anatomy, through analysis and interpretation of human variation. It will be an interdisciplinary project, supported by anatomists, anthropologists, geneticists, bioinformaticians, image analysts and computer scientists. We will investigate inherent and acquired variation in search of uniqueness, as the hand retains and displays a multiplicity of anatomical variants formed by different aetiologies (genetics, development, environment, accident etc). Hard biometrics, such as fingerprints, are well understood and some soft biometrics are gaining traction within both biometric and forensic domains (e.g. superficial vein pattern, skin crease pattern, morphometry, scars, tattoos and pigmentation pattern). A combinatorial approach of soft and hard biometrics has not been previously attempted from images of the hand. We will pioneer the development of new methods that will release the full extent of variation locked within the visible anatomy of the human hand and reconstruct its discriminatory profile as a retro-engineered multimodal biometric. A significant step change is required in the science to both reliably and repeatably extract and compare anatomical information from large numbers of images especially when the hand is not in a standard position or when either the resolution or lighting in the image is not ideal. Large datasets are vital for this work to be legally admissible. Through citizen engagement with science, this research will collect images from over 5,000 participants, creating an active, open source, ground-truth dataset. It will examine and address the effects of variable image conditions on data extraction and will design algorithms that permit auto-pattern searching across large numbers of stored images of variable quality. This will provide a major novel breakthrough in the study of anatomical variation, with wide-ranging, interdisciplinary and transdisciplinary impact.";2495377,99;2495377,99;ERC-2017-ADG;/ERC-ADG;LANCASTER UNIVERSITY;UK;UNIVERSITY OF DUNDEE;UK;;1;1;0;2;0;1 193265;633974;SOUND;SIGNED;H2020-EU.3.1.6.;PHC-32-2014;H2020;Statistical multi-Omics UNDerstanding of Patient Samples;2015-09-01;2018-08-31;;"Bioinformatic analysis is the biggest bottleneck in many genomic medicine projects. Our objective is to enable researchers to dramatically increase statistically informed use of personal multi-omic data in medicine. Soon, multiple types of omic technologies will be applied to 100,000s of patient-derived samples, with the three-stage goal of better understanding disease biology, discovery of new interventions, and personalizing the choice of treatment options. Our interdisciplinary team of biostatisticians, bioinformaticians, software developers and physician-scientists will address the analysis bottleneck with statistically and computationally sound methods. The SOUND consortium will (i) develop widely used and excellent bioinformatic and statistical methods and open source software for common but challenging tasks, including data pre-processing, data integration, statistical inference, visual presentation, and publication-quality reporting; (ii) introduce novel approaches to ground breaking multi-omics applications in oncology and medical genetics; (iii) develop interoperable data structures and software interfaces that enable seamless combination of tools; (iv) support a collaborative international academic and industry developer community; (v) enable rapid development and execution of high-quality software; (vi) lower the barrier to entry into this transdisciplinary field by providing simple, robust, easy-to-use solutions; and (vii) develop a training programme with regular courses and comprehensive online tutorials. Our aim is to create the de facto standard toolkit used in every clinical research lab for statistically informed analysis of personal multi-omic data. SOUND will increase research and innovation opportunities by reducing barriers of entry to genomic medicine across academic, healthcare and commercial sectors by translating in a rapid and efficient manner complex and innovative analytical approaches into modular, interoperable, reusable applications.";3656977,5;2953062,5;H2020-PHC-2014-two-stage;/RIA;EUROPEAN MOLECULAR BIOLOGY LABORATORY;DE;"BEDATADRIVEN BV;INSTITUTO DE ENGENHARIA MECANICA;LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN;THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;TECHNISCHE UNIVERSITAET MUENCHEN;HEALTH RESEARCH INC;DEUTSCHES KREBSFORSCHUNGSZENTRUM HEIDELBERG;EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH;UNIVERSITAETSKLINIKUM HEIDELBERG;UNIVERSITAT ZURICH;KLINIKUM RECHTS DER ISAR DER TECHNISCHEN UNIVERSITAT MUNCHEN;FRED HUTCHINSON CANCER RESEARCH CENTER NON PROFIT CORPORATION";"NL;PT;DE;UK;US;CH";;1;1;0;1;0;1 195973;660616;MALCOD;TERMINATED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Machine Learning for Computational Dynamics;2015-09-01;2017-08-31;;"The proposed research aims to establish groundbreaking new methods for the numerical analysis of dynamical systems by using tools from the field of machine learning. The intersection of the fields of machine learning and computational dynamics is largely unexplored, and this proposal aims at the first systematic development of a unified theory, with a view to applying the ideas to problems in the commercial and energy sectors. Recent results by the applicant in set approximation for control systems demonstrate the power of this approach, the results of which significantly improve on the current state-of-the-art methods for set approximation. This approach is based on a functional analytic framework frequently exploited in modern machine learning methods: the reproducing kernel Hilbert space (RKHS). Algorithms are designed to seek functions in the RKHS that characterise important dynamical properties of the system. This highly interdisciplinary research programme will develop a powerful and unified approach to create new algorithms that can either use input data generated from the evolution equations (if they are available) or measured data obtained directly from applications. The host institution PIK is a transdisciplinary host institution focused on climate modeling and sustainability. The tools developed during the course of the fellowship will be applied to the problem of basin stability and synchronisation of power grid networks. This proposal also includes two secondment phases to be spent at the non-academic partner organisation Ambrosys GmbH (AMB). There, the applicant will apply the research results to problems in image rendering in movies and turbulent flow across aerofoils, which are commercial applications already studied at AMB. The applicant will benefit from training in climate modeling and complex systems at PIK, and industrial training during the secondment phases.";171460,8;171460,8;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;POTSDAM INSTITUT FUER KLIMAFOLGENFORSCHUNG;DE;;;;1;1;0;1;0;1 213897;764056;PROSEU;SIGNED;H2020-EU.3.3.6.;LCE-31-2016-2017;H2020;PROSumers for the Energy Union: mainstreaming active participation of citizens in the energy transition;2018-03-01;2021-02-28;;PROSEU aims to enable the mainstreaming of the prosumer phenomenon into the European Energy Union. Prosumers are active energy users who both consume and produce renewable energy (RE). The growth of prosumerism all over Europe challenges current energy market structures and institutions. PROSEU research will look into new business models, market regulations, infrastructural integration, technology scenarios and energy policies. PROSEU’s interdisciplinary and transdisciplinary team will closely work together with RE Prosumer Initiatives (15 Living Labs), policymakers and other stakeholders from eight countries, following a quasi-experimental approach to learn how prosumer communities, start-ups and businesses are dealing with their own challenges, and to determine what incentive structures will enable the mainstreaming of RE Prosumerism, while safeguarding citizen participation, inclusiveness and transparency. Moving beyond a case by case and fragmented body of research on prosumers, PROSEU will build an integrated knowledge framework for a socio-political, socioeconomic, business and financial, technological, socio-technical and sociocultural understanding of RE prosumerism and coalesce in a comprehensive identification and assessment of incentive structures to enable the process of mainstreaming RE prosumers in the context of the energy transition.;3124073,75;3124073,75;H2020-LCE-2017-RES-RIA-TwoStage;/RIA;FCIENCIAS.ID - ASSOCIACAO PARA A INVESTIGACAO E DESENVOLVIMENTO DE CIENCIAS;PT;"ASOCIACION ECO-UNION;INSTITUT FUR OKOLOGISCHE WIRTSCHAFTSFORSCHUNG GmbH -IOW;CLIENTEARTH LBG;LEUPHANA UNIVERSITAT LUNEBURG;UNIVERSITY OF LEEDS;CE - ONDERZOEK, ADVIES ENCONSULTANCY VOOR DUURZAAMHEID BV;UNIVERSIDADE DO PORTO;ICLEI EUROPEAN SECRETARIAT GMBH (ICLEI EUROPASEKRETARIAT GMBH)*;DUTCH RESEARCH INSTITUTE FOR TRANSITIONS BV;SVEUCILISTE U ZAGREBU, FAKULTET STROJARSTVA I BRODOGRADNJE";"ES;DE;UK;NL;PT;HR";;1;1;0;1;0;1 212819;760090;ReSEED;SIGNED;H2020-EU.1.1.;ERC-2017-STG;H2020;Rescuing seeds’ heritage: engaging in a new framework of agriculture and innovation since the 18th century;2018-11-01;2023-10-31;;Humanity is facing a huge challenge: how to feed a growing population in a sustainable way? Scientists from different fields are looking for answers and ReSEED aims to assist such endeavours. Solutions depend on one key issue: seeds. We can have appropriate soil, climate or technologies, however without proper seeds it is impossible to guarantee food production. As historiography has given little attention to the role of seed varieties, there are many gaps in scientific knowledge. I argue that long-term historical analysis is critical to provide the best answers to current questions. ReSEED examines the changing connections between seeds, environment and human action, the triangle that has always underpinned agriculture, since the 18th century. The main objectives are as follows. 1) To map geographical changes in local crop distribution, paying attention to the new seeds made available by Columbian Exchange. 2) To outline which were the social networks supporting the circulation and cultivation of edible seed varieties, and at later date, checking how they articulated with state services. 3) To identify human factors that contribute to reducing, increasing, maintaining or restoring regional agro-biodiversity. 4) To assess the impacts of national and international decisions on local management of the triangle, mainly on farmers’ innovation. 5) To re-examine the long-term dynamics behind various European agricultural modernization itineraries. Based on innovative interdisciplinary and transdisciplinary methodologies, I build robust empirical research on the case of Iberian Peninsula in connection to empires, which allows thorough comparisons with other regions in Europe and beyond. ReSEED promotes strategies for win-win environmental/society outcomes, linking edible seeds to places and to innovations needed for food production. This is crucial to better understand how historical experiences can contribute to create solutions that ensure sustainable futures.;1467727;1467727;ERC-2017-STG;/ERC-STG;INSTITUTO DE CIENCIAS SOCIAIS;PT;;;;1;1;0;1;0;1 216028;770504;PERICLES;SIGNED;H2020-EU.3.6.3.1.;CULT-COOP-07-2017;H2020;PrEseRvIng and sustainably governing Cultural heritage and Landscapes in European coastal and maritime regionS;2018-05-01;2021-04-30;;"PERICLES promotes sustainable governance of cultural heritage (CH) in European coastal and maritime regions through the development of a theoretically grounded, multi-actor participatory framework. To meet this challenge, PERICLES has formed a strong interdisciplinary consortium comprised of research institutions, regional government and heritage partners representing 15 different disciplines. PERICLES addresses the following objectives: a) develop an in-depth, situated understanding of the CH of marine and coastal land/seascapes, including knowledge across local, spatial, environmental, social and economic aspects; b), develop practical tools, based on stakeholder involvement and participatory governance, for mapping, assessing and mitigating risks to CH and to enhance sustainable growth and increase employment by harnessing CH assets; c), provide policy advice to improve integration of CH in key marine and environmental policies and the implementation of associated EU directives; and d), develop effective knowledge exchange networks. To fulfill these objectives PERICLES uses a scientific approach guided by the theories of: a) space, place, and identity; b) resilience and adaptation; and c) deliberative and participatory governance. We will apply a range of participatory, deliberative and action research methods from the social sciences and arts directly involving decision-makers, stakeholders and the public. PERICLES meets the needs of the work program by: contributing to European efforts to promote evidence-based research on the impact of participatory approaches in CH policies and governance; using a multi- and transdisciplinary approach; addressing in/tangible CH in a geographically balanced way; involving and developing CH networks of local stakeholders and policy makers; and contributing to improved implementation of European policies on coastal zones and maritime areas and providing evidence on how to link environmental and cultural policies.";2498998,75;2498998,75;H2020-SC6-CULT-COOP-2017-two-stage;/RIA;AALBORG UNIVERSITET;DK;"ELLINIKOS GEORGIKOS ORGANISMOS - DIMITRA;THE SCOTTISH ASSOCIATION FOR MARINESCIENCE LBG;UNIVERSITE DE BRETAGNE OCCIDENTALE;MUINSUSKAITSEAMET;THE QUEEN'S UNIVERSITY OF BELFAST;UNIVERSIDADE DE AVEIRO;WAGENINGEN UNIVERSITY;UNIVERSITY OF THE HIGHLANDS AND ISLANDS LBG;SYNDACAT MIXTE DE GESTION DU PARC NATUREL REGIONAL DU GOLFE DU MORBIHAN";"EL;DK;FR;EE;UK;PT;NL";;1;1;0;1;0;1 197446;666004;HEIRRI;SIGNED;H2020-EU.5.a.;SEAC-2-2014;H2020;HEIRRI (Higher Education Institutions and Responsible Research and Innovation);2015-09-01;2018-08-31;;"Higher Education Institutions and Responsible Research and Innovation (HEIRRI) foster an alignment of research and innovation (R&I) with the needs, values and societal expectations. The six key aspects of “Responsible Research and Innovation (RRI)”-societal/public engagement, gender equality, open access, science education, ethics and governance in R&I-are transdisciplinary included at all stages of formation of scientist and engineers, and other professional fields involved in R&I. HEIRRI will create and share on OA a stock-taking inventory constituted by a State of the Art Review and a Data Base. The inventory will gather results of other EU funded RRI projects, good cases and practices of RRI and RRI Learning. Also, different stakeholders involved and/or affected by R&I will participate in a debate and reflection process on RRI Learning through online and offline Forum actions. Results from the inventory will represent the basis for RRI Training programs and formative materials, offering the students knowledge and skills to develop viable solutions to specific problems related to R&I, integrating theory and practice. They will be designed for the different HEI educational levels (undergraduate, MD and PhD, summer courses and MOOC), mainly based on Problem based learning methodology, and supported by multimedia materials (videos and microvideos, 2.0 materials, etc.). All results and products elaborated by HEIRRI will be uploaded on OA at RRITools Platform. An internationalization plan will guarantee their spreading awareness and future use by HEI from Europe and beyond. A global scope and expertise on RRI will be provided by HEIRRI consortium that consists of 5 European HEI (Universitat Pompeu Fabra (UPF), Universitetet I Bergen (UiB), Aarhus Universitet (AU), Institut Fuer Hoehere Studien und Wissenschaftliche Forschung (IHS), Sveuciliste u Splitu (University of Split, UNIST)), the European network of science centres and museums (AEESTI / Ecsite), Fundación Bancaria Caixa D'estalvis i Pensions de Barcelona La Caixa (FBLC), a network of universities (Associació Catalana d'Universitats Públiques, ACUP), and a private company specialized in R&I (INNOVATEC).";1498775;1498775;H2020-SEAC-2014-1;/CSA;UNIVERSIDAD POMPEU FABRA;ES;"INSTITUT FUER HOEHERE STUDIEN - INSTITUTE FOR ADVANCED STUDIES;AARHUS UNIVERSITET;SVEUCILISTE U SPLITU;FUNDACION BANCARIA CAIXA D'ESTALVISI PENSIONS DE BARCELONA LA CAIXA;SOCIEDAD PARA EL FOMENTO DE LA INNOVACION TECNOLOGICA S.L. - INNOVATEC;ASSOCIACIO CATALANA D'UNIVERSITATS PUBLIQUES;ASSOCIATION EUROPEENNE DES EXPOSITIONS SCIENTIFIQUES TECHNIQUES ET INDUSTRIELLES;UNIVERSITETET I BERGEN";"AT;DK;HR;ES;BE;NO";;0;1;0;0;0;1 221936;834033;AN-ICON;SIGNED;H2020-EU.1.1.;ERC-2018-ADG;H2020;An-Iconology: History, Theory, and Practices of Environmental Images;2019-09-01;2024-08-31;;"'Recent developments in image-making techniques have resulted in a drastic blurring of the threshold between the world of the image and the real world. Immersive and interactive virtual environments have enabled the production of pictures that elicit in the perceiver a strong feeling of being incorporated in a quasi-real world. In doing so such pictures conceal their mediateness (their being based on a material support), their referentiality (their pointing to an extra-iconic dimension), and their separateness (normally assured by framing devices), paradoxically challenging their status as images, as icons: they are veritable “an-icons”. This kind of pictures undermines the mainstream paradigm of Western image theories, shared by major models such as the doctrine of mimesis, the phenomenological account of image-consciousness, the analytic theories of depiction, the semiotic and iconological methods. These approaches miss the key counter-properties regarding an-icons as 'environmental' images: their immediateness, unframedness, and presentness. Subjects relating to an-icons are no longer visual observers of images; they are experiencers living in a quasi-real environment that allows multisensory affordances and embodied agencies. AN-ICON aims to develop “an-iconology” as a new methodological approach able to address this challenging iconoscape. Such an approach needs to be articulated in a transdisciplinary and transmedial way: 1) HISTORY – a media-archaeological reconstruction will provide a taxonomy of the manifold an-iconic strategies (e.g. illusionistic painting, pre-cinematic dispositifs, 3D films, video games, head mounted displays); 2) THEORY – an experiential account (drawing on phenomenology, visual culture and media studies) will identify the an-iconic key concepts; 3) PRACTICES – a socio-cultural section will explore the multifaceted impact of an-iconic images, environments and technologies on contemporary professional domains as well as on everyday life. '";2328736;2328736;ERC-2018-ADG;/ERC-ADG;UNIVERSITA DEGLI STUDI DI MILANO;IT;;;;0;1;0;0;0;1 220281;822357;URBANA;SIGNED;H2020-EU.3.6.1.4.;TRANSFORMATIONS-03-2018-2019;H2020;Urban Arena for sustainable and equitable solutions;2019-01-01;2021-12-31;;"UrbanA takes up the challenge of synthesizing and brokering the knowledge and experience generated in EU-funded projects, many of which have identified interventions that address grand societal challenges, of which urban inequalities and social exclusion across different contexts. In this way, UrbanA will support city-makers – including researchers, policymakers and practitioners – in transforming European cities into inclusive and sustainable urban and peri-urban environments. UrbanA will do so through a transdisciplinary Urban Arena for Sustainable and Equitable Solutions (established in WP2). By co-creatively mapping urban sustainability interventions (WP3), assessing their potential to improve urban social equity and inclusion (WP4) and identifying potential avenues and agents by which such interventions could be transferred to more widespread governance contexts (WP5), UrbanA will develop actionable and actor specific solutions (WP6), which will be disseminated to key local and European actors (WP7).";1499485;1499485;H2020-SC6-TRANSFORMATIONS-2018;/CSA;ICLEI EUROPEAN SECRETARIAT GMBH (ICLEI EUROPASEKRETARIAT GMBH)*;DE;"FCIENCIAS.ID - ASSOCIACAO PARA A INVESTIGACAO E DESENVOLVIMENTO DE CIENCIAS;ALBERT-LUDWIGS-UNIVERSITAET FREIBURG;KOZEP-EUROPAI EGYETEM;RESEAU EUROPEEN POUR DES INITIATIVES COMMUNAUTAIRES SUR LES CHANGEMENTS CLIMATIQUES ET LE DEVELOPPEMENT DURABLE;UNIVERSITAT AUTONOMA DE BARCELONA;DUTCH RESEARCH INSTITUTE FOR TRANSITIONS BV";"PT;DE;HU;BE;ES;NL";;0;1;0;0;0;1 212585;730994;TERRINet;SIGNED;H2020-EU.1.4.1.2.;INFRAIA-02-2017;H2020;The European Robotics Research Infrastructure Network;2017-12-01;2021-11-30;;"After a few decades of intense research and development, Robotics has produced radical innovation and impact in many sectors (manufacturing, space, medicine…). In addition Robotics has generated novel scientific and engineering knowledge. This is due to the unique nature of Robotics, that has evolved from a predominantly engineering-oriented domain, to a transdisciplinary area including and inspiring many different disciplines. Europe is an undisputed leader in Robotics: it has nurtured a large community of researchers, educated many thousand students, created large and small companies, and established advanced facilities for conducting scientific research and contributing to technological innovation. However, despite of significant efforts and achievements, the existing Robotics facilities are not fully synchronized, and lack common procedures, thus hampering their enormous potential for world class research and innovation. Creating a Robotics Research Infrastructure is realistic, timely and essential in the current and future landscape of Robotics. The European Robotics Research Infrastructures Network (TERRINet) project aims at building a world-class network with harmonised services and complementary capabilities where talented researchers from academia and industry worldwide will have access and will be able to explore new ideas and establish personal and joint projects; to get in contact with and be inspired by leading and creative scientists, technologists, experts and industrial representatives; to share information and gain knowledge for boosting their scientific research and potential for technological innovation. The plan of TERRINet is to accomplish its vision by providing not only an organised and well orchestrated set of facilities, but also databases, tools and methodologies which will remain operational after the end of the project, so to provide a long-term service to Robotics science and industry in Europe and worldwide.";4999236,25;4999236,25;H2020-INFRAIA-2017-1-two-stage;/RIA;SCUOLA SUPERIORE DI STUDI UNIVERSITARI E DI PERFEZIONAMENTO S ANNA;IT;"IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE;TECHNISCHE UNIVERSITAET MUENCHEN;COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES;UNIVERSITEIT TWENTE;ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE;UNIVERSITY OF THE WEST OF ENGLAND, BRISTOL;FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA;UNIVERSITAT POLITECNICA DE CATALUNYA;KARLSRUHER INSTITUT FUER TECHNOLOGIE;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;UNIVERZA V LJUBLJANI;UNIVERSIDAD DE SEVILLA";"UK;DE;FR;NL;CH;IT;ES;SI";;0;1;0;0;0;1 211741;765389;RECOMS;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2017;H2020;Building Resourceful and Resilient Communities through Adaptive and Transformative Environmental Practice;2018-03-01;2022-02-28;;"RECOMS will train 15 ESRs in transdisciplinary approaches to support resourceful and resilient community environmental practice, tackling societal challenges (e.g. food, energy and climate change), nurturing the potential of stakeholders and vulnerable groupings to create adaptive and transformative sustainability pathways. RECOMS will increase the mobility of ESRs, enhance their Scientific, Professional, Personal and Transferable Skills and impact on their career prospects as researchers, policy makers, facilitators, consultants, change agents, social innovators and environmental educators. The consortium of 7 beneficiaries and 4 partners comprised of public, private and non-profit organisations allows a comparative approach to studying community resourcefulness across a range of (trans) national settings in 6 EU countries. Fundamental is the coupled social-ecological and critical lens to evolutionary resilience thinking, as complex, dynamic and process based, denoting the capacity of a system to change. RECOMS raises capacities to implement practice-based solutions via 15 research projects, divided along 3 interconnected themes: Unlocking and Empowering; Adapting and Transforming; Collaborating and Connecting. RECOMS addresses EU goals of sustainable and inclusive growth and territorial resource-based development, enhancing social cohesion and social innovation. The joint training organised in training events includes integrated action-based learning, collaborative community practice, and experimenting with an assemblage of visual and creative interactive communication techniques. The joint training is complemented by online reflective learning portfolios, local training at hosting institutes, the job-training via secondments and the support of Specialist Practitioner Advisors. RECOMS will impact on varied target groups including communities and policy-makers, and share its outcomes with non-participants via a range of communication and dissemination activities.";3891072,6;3891072,6;H2020-MSCA-ITN-2017;/MSCA-ITN-ETN;COVENTRY UNIVERSITY;UK;"LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN;MINISTERIE VAN INFRASTRUCTUUR EN WATERSTAAT;EIGEN VERMOGEN VAN HET INSTITUUT VOOR LANDBOUW- EN VISSERIJONDERZOEK;LUONNONVARAKESKUS;UNIVERSITAET FUER BODENKULTUR WIEN;RIJKSUNIVERSITEIT GRONINGEN";"DE;NL;BE;FI;AT";;0;1;0;0;0;1 210512;730222;CONNECTING Nature;SIGNED;"H2020-EU.3.5.2.1.;H2020-EU.3.5.2.3.;H2020-EU.3.5.1.2.;H2020-EU.3.5.1.3.;H2020-EU.3.5.2.2.";SCC-02-2016-2017;H2020;COproductioN with NaturE for City Transitioning, INnovation and Governance;2017-06-01;2022-05-31;;The overarching objective of CONNECTING is to position Europe as a global leader in the innovation and implementation of nature-based solutions. The project partners will form a community of cities fostering peer-to-peer, transdisciplinary capacity-building between front-runner, fast-follower and multiplier cities. CONNECTING will co-develop the policy and practices necessary to scale up urban resilience, innovation and governance via nature-based solutions. An open innovation ecosystem approach bringing together city governments, SMEs, academia and civic society will be used to co-produce usable and actionable knowledge in all cities. CONNECTING will provide the reference framework for a new generation of urban nature-based solution processes and empower transitioning ambassadors who will globalise this approach through a strategy targeting multiplier cities. This novel approach, coupled with the high capacity of the consortium, makes CONNECTING an exciting prospect. In addition, linking all open-sourced data to the Oppla platform will ensure perpetuation beyond the end of the project.;11699286,15;11394282,48;H2020-SCC-NBS-2stage-2016;/IA;THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN;IE;"EMPRESA MUNICIPAL DE INICIATIVAS Y ACTIVIDADES EMPRESARIALES DE MALAGA SA;CENTER FOR ECOLOGICAL-NOOSPHERE STUDIES NATIONAL ACADEMY OF SCIENCES OF THE REPUBLIC OF ARMENIA;CLIMATE ALLIANCE - KLIMA-BUENDNIS - ALIANZA DEL CLIMA e.V.;GREENSPACE SCOTLAND;SUNGKYUNKWAN UNIVERSITY;CITTA METROPOLITANA DI BOLOGNA;STICHTING OSMOS;Ayuntamiento de A Coruna;GIS and RS Consulting Center GeoGraphic;UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN;GLASGOW CITY COUNCIL;ANAPTYXIAKI ETAIREIA LEFKOSIAS (ANEL) LTD;MUNICIPALITY OF IOANNINA;UNIWERSYTET IM. ADAMA MICKIEWICZA W POZNANIU;OPPLA EEIG;SARAJEVSKA REGIONALNA RAZVOJNA AGENCIJA SERDA DOO SARAJEVO;ABU INTERNATIONAL PROJECT MANAGEMENT LIMITED;STAD GENK;BIOAZUL, SL;Chinese Research Academy of Environmental Sciences;HUMBOLDT-UNIVERSITAET ZU BERLIN;UNIVERSITY OF EAST LONDON;MIASTO POZNAN;ICLEI EUROPEAN SECRETARIAT GMBH (ICLEI EUROPASEKRETARIAT GMBH)*;TTI-Technologie-Transfer-Initiative GmbH;DIMOS PAVLOU MILAS;UNIVERSIDADE DA CORUNA;OBSHTINA BURGAS;UNIVERSITATEA DE VEST DIN TIMISOARA;DUTCH RESEARCH INSTITUTE FOR TRANSITIONS BV;HELIX PFLANZEN GMBH;HORIZON NUA INNOVATION;URBANISTICNI INSTITUT REPUBLIKE SLOVENIJE";"ES;AM;DE;UK;KR;IT;NL;GE;IE;CY;EL;PL;BA;BE;CN;BG;RO;SI";;0;1;0;0;0;1 193867;641974;green.eu;SIGNED;H2020-EU.3.5.4.;SC5-14-2014;H2020;European Global Transition Network on Eco-Innovation, Green Economy and Sustainable Development;2015-02-01;2019-01-31;;"In the last two decades the world has experienced several crises. In light of these trends and to more effectively move towards sustainable development, several organisations and international actors have developed the concept of green economy as action-oriented approaches. Priority interventions are aimed at triggering technology adoption, and stimulate behavioural change. In fact, eco-innovation can be considered an enabler for a green economy to the same extent that the green economy can be understood as an enabler of sustainable development. Green.eu is designed to address these challenges, ranging the conceptualization of eco-innovation and the green economy, to the harmonization of the approaches needed to coherently assess performance, identify gaps (successes and failures) for the effective adoption of technologies that can create win-win results. In particular, the project is designed so as to improve (1) harmonization of definitions, (2) collection of relevant information on the performance of past and current efforts, and (3) coordination among stakeholders. Green.eu sees the main challenges in an improved understanding (and scientific assessment) of the concepts of green economy and eco-innovation, on the adaptation of policy agendas, the documentation of best practices and guidelines for knowledge transfer and transferability. The inter- and transdisciplinary green.eu network (including knowledge brokers, programme owners and global industry networks) is research based and aims to accelerate the transition towards a green economy significantly, with a European focus on co-development of knowledge. It aims to exploit win-win-opportunities and to improve the take up of R&D results. It includes the following work packages: Networking and co-ordination; Harmonization of concepts of green economy and eco-innovation; Eco-innovation policy agendas; Best practices, knowledge transfer, transferability; Integration and operationalization of lessons learned.";2994178,75;2994178,75;H2020-SC5-2014-one-stage;/CSA;NEDERLANDSE ORGANISATIE VOOR TOEGEPAST NATUURWETENSCHAPPELIJK ONDERZOEK TNO;NL;"FUNDACION TECNALIA RESEARCH & INNOVATION;RISE RESEARCH INSTITUTES OF SWEDEN AB;UNIVERSITEIT MAASTRICHT;ZEW - LEIBNIZ-ZENTRUM FUR EUROPAISCHE WIRTSCHAFTSFORSCHUNG GMBH MANNHEIM;KNOWLEDGE SRL;ICLEI EUROPEAN SECRETARIAT GMBH (ICLEI EUROPASEKRETARIAT GMBH)*;UNIVERSITY COLLEGE LONDON;STELLENBOSCH UNIVERSITY;KING'S COLLEGE LONDON;UNIVERSITA DEGLI STUDI DI FERRARA;GREENOVATE ! EUROPE";"ES;SE;NL;DE;IT;UK;ZA;BE";;0;1;0;0;0;1 205707;723649;MPC-. GT;SIGNED;H2020-EU.3.3.1.;EE-04-2016-2017;H2020;"Model Predictive Control and Innovative System Integration of GEOTABS;-) in Hybrid Low Grade Thermal Energy Systems - Hybrid MPC GEOTABS";2016-09-01;2020-08-31;;"The MPC-: GT project brought together a transdisciplinary team of SMEs, large industry and research institutes, experienced in research and application of design and control systems in the combined building and energy world. Based on prior research, supported by (joint) EU and national projects, and practical experience the bottlenecks where identified that prevent at this moment a real breakthrough of geothermal heat pumps (GEO-HP) combined with thermally activated building systems (TABS) - GEOTABS. Solutions, which need to be implemented in an integrated way, were identified and sufficient proof of concept was gathered to join forces in a RIA. The innovative concepts aim at increasing the share of low valued (low-grade) energy sources by means of using low exergy systems on the one hand and aim at upgrading low/moderate temperature resources on the other hand. The overall solution consists of an optimal integration of GEOTABS and secondary supply and emission systems. To allow for an optimal use of both the GEOTABS and the secondary system, a split will be made between a so-called “base load” that will be provided by the GEOTABS and the remaining energy needs that should be supplied by the secondary system. A generic rule, eliminating case-by-case simulation work, will be developed. The second part of the proposed solution aims at a white box approach for Model Predictive Control (MPC) to generate a controller model with precomputed model inputs such as disturbances and HVAC thermal power to avoid case by case development. Research is needed to assess the overall performance and robustness of such an approach towards uncertainties. As such, the MPC-: GT consortium believes to have identified an integrated solution that will provide a near optimal design strategy for the MPC GEOTABS concept using optimal control integrated design. The solution will support the industry, especially the SME members, to expand their activities and strengthen their competitiveness.";4263701,25;3989951,25;H2020-EE-2016-RIA-IA;/RIA;UNIVERSITEIT GENT;BE;"ENERGOKLASTR;LEMON CONSULT AG;UNIVERSITEIT MAASTRICHT;STUDIEBUREAU BOYDENS RAYMOND;CLIMATE FUTURES LIMITED;UPONOR OYJ;GEOTHERMAL ENERGY SL;DANMARKS TEKNISKE UNIVERSITET;VIESSMANN WERKE GMBH & CO KG;KATHOLIEKE UNIVERSITEIT LEUVEN;FEDERATIE VAN VERENIGINGEN VOOR VERWARMING EN LUCHTBEHANDELING IN EUROPA VERENIGING";"CZ;CH;NL;BE;UK;FI;ES;DK;DE";;0;1;0;0;0;1 205997;727852;Blue-Action;SIGNED;"H2020-EU.3.2.5.;H2020-EU.3.5.1.";BG-10-2016;H2020;Arctic Impact on Weather and Climate;2016-12-01;2021-02-28;;"Blue-Action will provide fundamental and empirically-grounded, executable science that quantifies and explains the role of a changing Arctic in increasing predictive capability of weather and climate of the Northern Hemisphere.To achieve this Blue-Action will take a transdisciplinary approach, bridging scientific understanding within Arctic climate, weather and risk management research, with key stakeholder knowledge of the impacts of climatic weather extremes and hazardous events; leading to the co-design of better services.This bridge will build on innovative statistical and dynamical approaches to predict weather and climate extremes. In dialogue with users, Blue-Arctic will take stock in existing knowledge about cross-sectoral impacts and vulnerabilities with respect to the occurrence of these events when associated to weather and climate predictions. Modeling and prediction capabilities will be enhanced by targeting firstly, lower latitude oceanic and atmospheric drivers of regional Arctic changes and secondly, Arctic impacts on Northern Hemisphere climate and weather extremes. Coordinated multi-model experiments will be key to test new higher resolution model configurations, innovative methods to reduce forecast error, and advanced methods to improve uptake of new Earth observations assets are planned. Blue-Action thereby demonstrates how such an uptake may assist in creating better optimized observation system for various modelling applications. The improved robust and reliable forecasting can help meteorological and climate services to better deliver tailored predictions and advice, including sub-seasonal to seasonal time scales, will take Arctic climate prediction beyond seasons and to teleconnections over the Northern Hemisphere. Blue-Action will through its concerted efforts therefore contribute to the improvement of climate models to represent Arctic warming realistically and address its impact on regional and global atmospheric and oceanic circulation.";8103125;7500000;H2020-BG-2016-1;/RIA;DANMARKS METEOROLOGISKE INSTITUT;DK;"SAMS RESEARCH SERVICES LIMITED;FEDERAL STATE BUDGETARY INSTITUTION - INSTITUTE OF WORLD ECONOMY AND INTERNATIONAL RELATIONS OF THE RUSSIAN ACADEMY OF SCIENCES;DANMARKS PELAGISKE PRODUCENTORGANISATION FORENING;INSTITUTE OF ATMOSPHERIC PHYSICS OFCHINESE ACADEMY OF SCIENCES;UNI RESEARCH AS;HAVSTOVAN;UNIVERSITY CORPORATION FOR ATMOSPHERIC RESEARCH NONPROFIT CORPORATION;WOC - WORLD OCEAN LIMITED;THE UNIVERSITY OF READING;UNIVERSITY OF WASHINGTON;THE SCOTTISH ASSOCIATION FOR MARINESCIENCE LBG;FUNDACIO INSTITUT CATALA DE CIENCIES DEL CLIMA;LAPIN YLIOPISTO;STICHTING NIOZ, KONINKLIJK NEDERLANDS INSTITUUT VOOR ONDERZOEK DER ZEE;HAFRANNSOKNASTOFNUN, RANNSOKNA- OG RADGJAFARSTOFNUN HAFS OG VATNA;FUNDACION PRIVADA INSTITUTO DE SALUD GLOBAL BARCELONA;STICHTING NETHERLANDS ESCIENCE CENTER;NATIONAL UNIVERSITY OF IRELAND MAYNOOTH;UNIVERSITAET HAMBURG;MARINE SCOTLAND;DNV GL AS;ORGANIZATION OF THE RUSSIAN ACADEMYOF SCIENCES A.M. OBUKHOV INSTITUTEOF ATMOSPHERIC PHYSICS RAS;CLIMATE-KIC APS;MEOPAR INCORPORATED;UNITED KINGDOM RESEARCH AND INNOVATION;STIFTELSEN NANSEN SENTER FOR MILJOOG FJERNMALING;UNIVERSITY OF SOUTHAMPTON;EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH;DANMARKS TEKNISKE UNIVERSITET;PELAGIC FREEZER TRAWLER ASSOCIATION;FORESIGHT INTELLIGENCE GBR;RUKAKESKUS OY;HAFRANNSOKNASTOFNUNIN;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;FONDAZIONE CENTRO EURO-MEDITERRANEOSUI CAMBIAMENTI CLIMATICI;WOODS HOLE OCEANOGRAPHIC INSTITUTION;HELMHOLTZ ZENTRUM FUR OZEANFORSCHUNG KIEL;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;MERCATOR OCEAN;STICHTING NEDERLANDSE WETENSCHAPPELIJK ONDERZOEK INSTITUTEN;CAMARA MUNICIPAL DE ALMADA;NORCE NORWEGIAN RESEARCH CENTRE AS;INSTITUTE FOR ADVANCED SUSTAINABILITY STUDIES EV;UNIVERSITETET I BERGEN;YONSEI UNIVERSITY;NATURAL ENVIRONMENT RESEARCH COUNCIL;KONSORTIUM DEUTSCHE MEERESFORSCHUNG e.V.";"UK;RU;DK;CN;NO;FO;US;ES;FI;NL;IS;IE;DE;CA;CH;IT;FR;PT;KR";;0;1;0;0;0;1 205545;721185;NEW-MINE;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2016;H2020;EU Training Network for Resource Recovery through Enhanced Landfill Mining;2016-09-01;2020-08-31;;"Europe has somewhere between 150,000 and 500,000 landfill sites, with an estimated 90% of them being “non-sanitary” landfills, predating the EU Landfill Directive of 1999. These older landfills tend to be filled with municipal solid waste and often lack any environmental protection technology. In order to avoid future environmental and health problems, many of these landfills will soon require expensive remediation measures. This situation might appear bleak, but it does present us with an exciting opportunity for a combined resource-recovery and remediation strategy, which will drastically reduce future remediation costs, reclaim valuable land, while at the same time unlocking billions of tonnes of valuable resources contained within these landfills. However, the widespread adoption of Enhanced Landfill Mining (ELFM) in the EU, as envisaged by NEW-MINE, urgently requires skilled scientists, engineers, economists and policy makers who can develop cost-effective, environmentally friendly ELFM practices and regulatory frameworks. All this demands a European commitment to concerted, inter- and transdisciplinary research and innovation. The NEW-MINE project trains 15 early-stage researchers (ESRs) in all the aspects of landfill mining, in terms of both technological innovation and multi-criteria assessments for ELFM. The technological innovation follows a value-chain approach, from advanced landfill exploration, mechanical processing, plasma/solar/hybrid thermochemical conversion and upcycling, while the multi-criteria assessment methods allow the ESRs to compare combined resource-recovery/remediation ELFM methods with the “Do-Nothing”, “Classic remediation” and “Classic landfill mining with (co-)incineration” scenarios. By training the ESRs in scientific, technical and a range of soft skills, all based on a collaboration involving EU-leading institutes, they become highly sought-after scientists and engineers for the rapidly emerging ELFM and recycling industries.";3836165,55;3836165,55;H2020-MSCA-ITN-2016;/MSCA-ITN-ETN;KATHOLIEKE UNIVERSITEIT LEUVEN;BE;"LINKOPINGS UNIVERSITET;KUNGLIGA TEKNISKA HOEGSKOLAN;MONTANUNIVERSITAET LEOBEN;UNIVERSITEIT GENT;RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN;ITALCEMENTI FABBRICHE RIUNITE CEMENTO SPA;RENEWI VALORISATION & QUARRY;UNIVERSITA DEGLI STUDI DI PADOVA;EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH";"SE;AT;BE;DE;IT;CH";;0;1;0;0;0;1 201373;705862;Exosomes;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Regulated secretion and role of urinary nanovesicles;2017-09-01;2019-08-31;;Extracellular nanovesicles called “exosomes” are small membrane-bound vesicles that are secreted by a variety of cell types. Exosomes contain various molecular constituents of their cell of origin, incl. proteins and genetic materials. The exosome release pathway contributes towards protein secretion, antigen presentation and pathogen transfer and roles of exosomes in intercellular communications and transfer of materials have been studied in immunology, neurobiology, stem cell and tumor biology. Exosomes are also released into the urine, although their role in urine is unclear and provides the basis of this fellowship. To gain novel information about urinary exosomes, a transdisciplinary approach is required. I will use my current knowledge of qualitative and quantitative proteomics combined with extensive bioinformatics to study urinary and renal exosomes and their ‘cargo’ secreted under normal and pathophysiological conditions. I will combine this information with new ideas and techniques I will learn in my host laboratory to examine rates of exosome secretion and to assess whether exosomes have the capacity to inhibit the growth of bacteria. Methodologies in this fellowship include techniques which I have extensive experience of e.g. large scale proteomic profiling, and novel techniques that I will learn in the host lab to enhance my research portfolio and future career prospects, including cell biological and microbiological techniques and experience in collecting/using samples from patients. The scientific goals of the project are to investigate the underlying mechanisms for regulated exosome secretion and the role of exosomes in innate immunity. As exosomes are secreted from multiple cell types, this study will have major implications for a variety of biology disciplines. The fellowship will develop my career by providing new novel laboratory skills, it will give me greater freedom to independently run a research project and increase my int collaborations.;200194,8;200194,8;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;AARHUS UNIVERSITET;DK;;;;0;1;0;0;0;1 205869;727895;SheepNet;SIGNED;"H2020-EU.3.2.4.;H2020-EU.3.2.1.;H2020-EU.3.2.2.";RUR-10-2016-2017;H2020;Sharing Expertise and Experience towards sheep Productivity through NETworking;2016-11-01;2019-10-31;;"'SheepNet is a thematic network project about practice-driven innovation to improve sheep productivity (number of lambs weaned/ewe mated): a critical component of farmers’ income and therefore of the sustainability and attractiveness of sheep farming. SheepNet will establish durable exchange of scientific and practical knowledge among researchers, farmers and advisors, through a multi-actor and transdisciplinary approach at national and international levels and by the broad involvement of European Agriculture knowledge and Innovation Systems. This will promote the implementation and dissemination of innovative and best technologies and practices for the improvement of sheep productivity. To maximize impact and ensure a wide coverage of different farming systems, SheepNet will bring together six main sheep producing EU countries, plus Turkey, and Australia, New Zealand, and every relevant EU network. The project aims to: • produce a scientific, technical and practical knowledge reservoir through a combined 'top-down and bottom-up' approach and the strong involvement of 45 innovative farms; • foster cross-fertilization through multi-actors workshops at national and international levels, a broad and interactive participation of the 'sheep community' via social networks and an interactive platform; • develop an easily understandable support package of communication and learning material, web-based tools, interactive platform, designed to help both scientists and stakeholders and a strong interactions with the EIP AGRI Service Point will guarantee long-lasting and wide accessibility of the SheepNet results.'";1995289,38;1991289,5;H2020-RUR-2016-1;/CSA;INSTITUT DE L'ELEVAGE;FR;"TOGEN DANISMANLIK TARIM VE HAYVANCILIK ZIRAAT GIDA BIOTEKNOLOJI ITHALAT IHRACAT SAN VE TIC LTD;UNIVERSITATEA DE STIINTE AGRICOLE SI MEDICINA VETERINARA A BANATULUI REGELE MIHAI I AL ROMANIEI DIN TIMISOARA;EFFICIENT INNOVATION SAS;SRUC;AGRIS SARDEGNA - AGENZIA PER LA RICERCA IN AGRICOLTURA;TEAGASC - AGRICULTURE AND FOOD DEVELOPMENT AUTHORITY;NEIKER-INSTITUTO VASCO DE INVESTIGACION Y DESARROLLO AGRARIO SA;INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE";"TR;RO;FR;UK;IT;IE;ES";;0;1;0;0;0;1 199274;687548;SMS;CLOSED;H2020-EU.2.1.6.;COMPET-03-2015;H2020;SANDWICH MATERIAL AND STRUCTURE;2016-01-01;2018-04-30;;"In the space industry, a growing demand is to make structures lighter, while optimizing the mass/stiffness/strength ratio.. To do so, the sandwich architecture appears to be the most efficient design. The main objective of Sandwich Material and Structure (SMS) project is then to develop an ultra-stable and low weight structure, based on such architecture. This optimized structure will combine innovative solutions such as cyanate-ester / pitch fiber Carbon Fiber Reinforced Polymer (CFRP) raw material, cyanate-ester / pitch fiber CFRP honeycomb and advanced joining solutions. To validate the performance of such assembly, SMS will work on a sandwich mirror structure use case.. The development of a groundbreaking joining solution, based on organic, inorganic or hybrid chemistry, will ensure optimal structural cohesion. The implementation of Zerodur® skins to create the mirror will allow to measure optical performances and to characterize the stability of the structure. SMS work plan includes the identification of requirements at system and building blocks level, the development of European sourced cyanate-ester CFRP and CFRP honeycomb, the tuning of an efficient joining method and a Breadboard prototyping and tests. SMS project will ensure the compatibility of its developments with the European legislation and regulation, as well as foresee their up-scaling at industrial level and their dissemination towards research groups and SMEs. All the achievements will focus on developing a range of new space products from non-space low TRL technologies. At project end, SMS will achieve a Technological Readiness Level (TRL) 4-5, with the identification of the way forward to qualify and industrialize very large scale structures. SMS will be supported by a well-balanced and transdisciplinary consortium, with previous common experience in carrying out successful material and processes development projects.";1187742,5;817992,5;H2020-COMPET-2015;/RIA;THALES ALENIA SPACE FRANCE;FR;"ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE;NORTH THIN PLY TECHNOLOGY SARL;MATERIA NOVA ASBL;NORTH THIN PLY TECHNOLOGY SPOO.;POLITECNICO DI TORINO";"CH;BE;PL;IT";;0;1;0;0;0;1 199024;687828;its4land;SIGNED;H2020-EU.2.1.1.;ICT-39-2015;H2020;Geospatial technology innovations for land tenure security in East Africa;2016-02-01;2020-01-31;;its4land delivers an innovative suite of land tenure recording tools that responds to sub Saharan Africa’s immense challenge to rapidly and cheaply map millions of unrecognized land rights in the region. ICT innovation will play a key role. Existing approaches have failed: disputes abound, investment is impeded, and the community’s poorest lose out. its4land reinforces strategic collaboration between the EU and East Africa via a scalable and transferrable ICT solution. Established local, national, and international partnerships drive the project results beyond R&D into the commercial realm. its4land combines an innovation process with emerging geospatial technologies, including smart sketchmaps, UAVs, automated feature extraction, and geocloud services, to deliver land recording services that are end-user responsive, market driven, and fit-for-purpose. The transdisciplinary work also develops supportive models for governance, capacity development, and business capitalization. Gender sensitive analysis and design is also incorporated. Set in the East African development hotbeds of Rwanda, Kenya, and Ethiopia, its4land falls within TRL 5-7: 3 major phases host 8 work packages that enable contextualization, design, and eventual land sector transformation. In line with Living Labs thinking, localized pilots and demonstrations are embedded in the design process. The experienced consortium is multi-sectorial, multi-national, and multidisciplinary. It includes SMEs and researchers from 3 EU countries and 3 East African countries: the necessary complementary skills and expertise is delivered. Responses to the range of barriers are prepared: strong networks across East Africa are key in mitigation. The tailored project management plan ensures clear milestones and deliverables, and supports result dissemination and exploitation: specific work packages and roles focus on the latter.;3933740;3933740;H2020-ICT-2015;/RIA;UNIVERSITEIT TWENTE;NL;"THE TECHNICAL UNIVERSITY OF KENYA;HANSA LUFTBILD AG;Institut d'Enseignement Superieur de Ruhengeri;BAHIR DAR UNIVERSITY;WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER;KATHOLIEKE UNIVERSITEIT LEUVEN;ESRI RWANDA";"KE;DE;RW;ET;BE";;0;1;0;0;0;1 197077;633838;PROVIDE;SIGNED;H2020-EU.3.2.;ISIB-01-2014;H2020;PROVIding smart DElivery of public goods by EU agriculture and forestry;2015-09-01;2018-08-31;;"'The objective of the project is to provide a conceptual basis, evidence, tools and improved incentive and policy options to support the 'smart' provision of public goods by the EU agriculture and forestry ecosystems, in the light of trade-offs and conflicts brought about by prospective intensification scenarios, using a transdisciplinary approach. PROVIDE will consider a wide range of public goods, including the scope for intensification to produce negative externalities, in relation with a wide set of legislations. It will address the issue in a multi-scale framework working both at the EU level and at case study level in thirteen Countries of the EU. The practical results of the project will be: a renewed (“un-packed”) conceptualization of the notion of public goods; an operational framework to support the smart provision of public goods; a toolbox putting together an inventory/mapping of options, operational means for valuation and evaluation, and a selection of evaluated policy/sector mechanisms; a consolidated and long-lasting community of knowledge and practice. The project will achieve the above results through a mapping and inventory of public goods and the mechanisms producing such goods, allowing to identify ’hotspots’ for mechanisms and policy development. Around these ’hotspots’, the project will then value different public goods and explore value transferability across several regions and ecosystems. Next, to meet a smart production of public goods, consistent with the current needs of productivity, bioeconomy strategy and rural development, innovative policy tools and mechanisms will be comparatively assessed and evaluated. The outcomes of these activities will feed information into the framework and toolbox. All these processes will be co-developed with stakeholders, so that the framework and toolbox will be a co-constructed product allowing incremental development also beyond the lifetime of the project, maximizing PROVIDE’s impact.'";2991436,25;2991436,25;H2020-ISIB-2014-2;/RIA;ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA;IT;"UNIWERSYTET WARSZAWSKI;THE JAMES HUTTON INSTITUTE;STICHTING VU;LUONNONVARAKESKUS;UNIVERSITATEA ALEXANDRU IOAN CUZA DIN IASI;INSTITUTE OF AGRICULTURAL ECONOMICS;UNIVERSIDAD DE CORDOBA;UNIVERSITAET FUER BODENKULTUR WIEN;ISTITUTO DELTA ECOLOGIA APPLICATA SRL;INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE;LEIBNIZ-ZENTRUM FUER AGRARLANDSCHAFTSFORSCHUNG (ZALF) e.V.;TECHNOLOGICKE CENTRUM AKADEMIE VED CESKE REPUBLIKY;TALLINN UNIVERSITY";"PL;UK;NL;FI;RO;BG;ES;AT;IT;FR;DE;CZ;EE";;0;1;0;0;0;1 212381;770256;SEnECA;SIGNED;H2020-EU.3.6.1.3.;ENG-GLOBALLY-07-2017;H2020;Strengthening and Energizing EU-Central Asia relations;2018-01-01;2019-12-31;;The relations to Central Asia are an important element of the changing transatlantic and geopolitical setting the EU is currently facing. They are influenced by the role the rest of Asia and other world powers play in the region, which the EU has to take into consideration while focusing on its comparative advantages. The main objectives of SEnECA are to strengthen and energize EU-Central Asia relations by establishing a sustainable, transdisciplinary SEnECA Research Network and the SEnECA Stakeholder Network to link European and Central Asian researchers, policy makers and stakeholders in order to improve research cooperation to develop a common SEnECA Agenda for Future Research Cooperation and EU’s Central Asia policy by setting up the SEnECA Policy Roadmap. The SEnECA Communication Plan for dissemination and awareness-raising will promote the importance of Central Asia to Europe among scholars, policy-makers, stakeholders in education, media, civil society and the EU public sphere notably through the SEnECA Exhibition. SEnECA will thus ultimately strengthen capacities in research and policy advice through the SEnECA Academic Policy Advice Training. Within two years, twelve consortium members from think tanks, universities and NGOs in Europe and Central Asia build on their Trans-European and Central Asian network with research institutions in 41 European, Central Asian and other Asian countries. Through its activities, SEnECA maps existing networks of researchers of Central Asian Studies in Europe and European Studies in Central Asia and key actors in education and media active in EU-Central Asia relations to analyse research cooperation, policies and communication on Central Asia to set up the SEnECA Research Database which forms the basis for recommending priorities and new forms of scientific cooperation following the “blended research” approach and demand-driven policy advice based on an inclusive approach to EU policy-makers and stakeholders active in EU-Central Asia relations.;1499857;1499857;H2020-SC6-ENG-GLOBALLY-2017;/CSA;UNIVERSITAET DUISBURG-ESSEN;DE;"LATVIJAS ARPOLITIKAS INSTITUTS;YNANCH WEPA;WISEEUROPA - FUNDACJA WARSZAWSKI INSTYTUT STUDIOW EKONOMICZNYCH I EUROPEJSKICH;KYRGYZ NATIONAL UNIVERSITY NAMED AFTER JUSUP BALASAGYN;ANNA GUSSAROVA;Trans European Policy Studies Association;ROYAL UNITED SERVICES INSTITUTE FOR DEFENCE AND SECURITY STUDIES;INSTITUT FUR EUROPAISCHE POLITIK EV;JAHON OITISODIYOTI VA DIPLOMATIVA UNIVERSITETI;CENTRE INTERNATIONAL DE FORMATION EUROPEENNE;CENTER OF SOCIOLOGICAL RESEARCHES ZERKALO";"LV;TM;PL;KG;KZ;BE;UK;DE;UZ;FR;TJ";;0;1;0;0;0;1 208914;747124;TIMPANI;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Test, Predict, and Improve Musical Scene Perception of Hearing-Impaired Listeners;2018-09-01;2020-08-31;;In both speech and music perception, the auditory system decomposes sounds that overlap in time and frequency into distinct perceptual events and streams, which is referred to as auditory scene analysis (ASA). Hearing-impaired listeners suffer from severely compromised ASA, as illustrated by their immense difficulties to understand speech in noisy environments. Although the central role of ASA in shaping the experience of music is widely acknowledged—perceptually organizing sounds from multiple instruments or voices into melody and accompaniment, for instance—the role of hearing loss in musical scene perception remains largely unexplored. At the same time, hearing aids are typically designed for speech perception, not for music perception. Adopting a transdisciplinary approach that employs methods from music perception, auditory modelling, and signal processing, this Marie Sk³odowska-Curie Action aims to Test, Predict, and Improve Musical Scene Perception of Hearing-Impaired Listeners (TIMPANI). Firstly, a series of music perception tasks will be designed to assess the effects of hearing loss on musical scene perception abilities. Secondly, an auditory model will be developed in order to predict normal and hearing-impaired listeners’ performance in ASA tasks. Finally, algorithms for scene-aware music mixing will be developed for improved music perception of hearing aid users. This research is timely and addresses the H2020 challenges to improve demographic change and wellbeing in European societies: The rise of hearing loss calls for scientific and technological breakthroughs in order to include hearing-impaired individuals in the cultural resource of music listening and making.;171460,8;171460,8;H2020-MSCA-IF-2016;/MSCA-IF-EF-RI;CARL VON OSSIETZKY UNIVERSITAET OLDENBURG;DE;;;;0;1;0;0;0;1 200116;693642;SMART;SIGNED;H2020-EU.3.6.;INT-04-2015;H2020;Sustainable Market Actors for Responsible Trade;2016-03-01;2020-02-29;;"This Project aims to address an increasingly pressing global challenge: How to achieve the EU’s development goals and the UN’s Sustainable Development Goals, while meeting the global target of staying within two degrees global warming and avoid transgressing other planetary boundaries. EU policies must align with sustainable development goals (Article 11 TFEU). The impacts of climate change and global loss of natural habitat undermine the progress achieved by pursuing the Millennium Development Goals and threaten the realisation of EU development policy goals. Our focus is the role of EU’s public and private market actors. They have a high level of interaction with actors in emerging and developing economies, and are therefore crucial to achieving the EU’s development goals. However, science does not yet cater for insights in how the regulatory environment influences their decision-making, nor in how we can stimulate them to make development-friendly, environmentally and socially sustainable decisions. Comprehensive, ground-breaking research is necessary into the regulatory complexity in which EU private and public market actors operate, in particular concerning their interactions with private and public actors in developing countries. Our Consortium, leading experts in law, economics, and applied environmental and social science, is able to analyse this regulatory complexity in a transdisciplinary and comprehensive perspective, both on an overarching level and in depth, in the form of specific product life-cycles: ready-made garments and mobile phones. We bring significant new evidence-based insights into the factors that enable or hinder coherence in EU development policy; we will advance the understanding of how development concerns can be successfully integrated in non-development policies and regulations concerning market actors; and we provide tools for improved PCD impact assessment as well as for better corporate sustainability assessment.";3717997,5;2491210;H2020-INT-SOCIETY-2015;/RIA;UNIVERSITETET I OSLO;NO;"AARHUS UNIVERSITET;UNIVERSITY OF GHANA;UNIVERSITAT JAUME I DE CASTELLON;BGMEA INSTITUTE OF FASHION & TECHNOLOGY;THE UNIVERSITY OF SHEFFIELD;SHANGHAI JIAO TONG UNIVERSITY;TAX JUSTICE NETWORK LIMITED;NORUT NORTHERN RESEARCH INSTITUTE AS;FORSKNINGSSTIFTELSEN FAFO;KOBENHAVNS UNIVERSITET;UNIVERZITA KOMENSKEHO V BRATISLAVE;INSTYTUT ALLERHANDA;CICERO SENTER KLIMAFORSKNING STIFTELSE;UNIVERSITEIT NYENRODE BV;COPENHAGEN BUSINESS SCHOOL;DEAKIN UNIVERSITY;UNIVERSITA DEGLI STUDI DI SASSARI;CITY UNIVERSITY OF HONG KONG;UNIVERSITY OF BRISTOL;UNIVERSITY OF TASMANIA;TURUN YLIOPISTO;UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK;POLSKI INSTYTUT PRAW CZLOWIEKA I BIZNESU - PIHRB;STOCKHOLMS UNIVERSITET";"DK;GH;ES;BD;UK;CN;NO;SK;PL;NL;AU;IT;HK;FI;IE;SE";;0;1;0;0;0;1 198353;679386;EPOS;SIGNED;H2020-EU.2.1.5.3.;SPIRE-06-2015;H2020;Enhanced energy and resource Efficiency and Performance in process industry Operations via onsite and cross-sectorial Symbiosis;2015-10-01;2019-09-30;;"Out of the community created by SPIRE covering industrial and research actors throughout Europe, the EPOS project brings together 6 global process industries from 6 key relevant sectors: steel, cement, minerals, chemicals, bio-based/life science products and engineering. Together they represent 166 bn € in sales with 75% of their production located in Europe. The 6 industries joined forces with 2 excellent science institutes and 4 highly R&I minded SMEs, building the EPOS consortium with Ghent University as coordinator. With the aim of reinforcing competitiveness of the EU industry, it is the ambition of the EPOS partners to gain cross-sectorial knowledge and investigate cluster opportunities using an innovative Industrial Symbiosis (IS) platform to be developed and validated during the project. The main objective is to enable cross-sectorial IS and provide a wide range of technological and organisational options for making business and operations more efficient, more cost-effective, more competitive and more sustainable across process sectors. The expected impact is clearly in line with the SPIRE roadmap - and sector associations, city councils (in the districts where EPOS is deployed), the SPIRE PPP as well as standardisation bodies are committed to participate in the EPOS transdisciplinary advisory board. The EPOS project spans 48 months and its structure builds on activities that ensure the project challenge is addressed in an optimal way, including cross-sectorial key performance indicators, sector profiles and cross-sector markets, IS toolbox development, training and validation of the (simple and single) IS management tool in 5 clusters strategically located throughout EU (i.e. France, Poland, Switzerland and UK). Entire work packages are dedicated to dissemination and to define realistic business scenarios for the exploitation of the EPOS tool and the proven, overall cost-reducing IS cluster activities, in view of a wide uptake and a broad EPOS outreach.";5191388,27;3707418,75;H2020-SPIRE-2015;/RIA;UNIVERSITEIT GENT;BE;"BELSIM ENGINEERING;CIMARK SA;STRANE INNOVATION SAS;INEOS TECHNOLOGIES FRANCE SAS;ARCELORMITTAL MAIZIERES RESEARCH SA;CEMEX RESEARCH GROUP AG;LONZA AG;ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE;CEMEX POLSKA SP ZOO;KORONA INZENIRING DD;VEOLIA ENVIRONNEMENT RECHERCHE ET INNOVATION SNC;OMYA UK LIMITED;QUANTIS;BELSIM";"BE;CH;FR;PL;SI;UK";;0;1;0;0;0;1 214294;773830;One Health EJP;SIGNED;"H2020-EU.3.2.1.1.;H2020-EU.3.2.2.2.";SFS-36-2017;H2020;Promoting One Health in Europe through joint actions on foodborne zoonoses, antimicrobial resistance and emerging microbiological hazards.;2018-01-01;2022-12-31;;"The One Health concept recognizes that the human health is tightly connected to the health of animals and the environment, i.e. that animal feed, human food, animal and human health, and environmental contamination are closely linked. These are the main focus of our European joint programme (EJP). One reference laboratory from the public health / medicine domain and one reference laboratory from the food / veterinary domain are associated within a network of 41 European laboratories and research centers, distributed in 19 participating member states, with the aim to reach significant advances in the fields of foodborne zoonoses (FBZ), antimicrobial resistance (AMR) and emerging threats (ET) within a global One Health approach. Most of these laboratories have reference responsibilities, representing a sustainable framework for an integrated research community. Consistent with the “Prevent-Detect-Respond” concept, the One Health EJP aims at reinforcing collaboration between institutes by enhancing transdisciplinary cooperation and integration of activities by means of dedicated Joint Research Projects, Joint Integrative Project and through education and training in the fields of FBZ, AMR and ET. While alignment and harmonization with on-going EC-funded research project will also be considered, deliverables from the EJP activities should feed the approach of evidence based risk assessment and therefore the management of risks by the competent national authorities. Therefore, it is of utmost importance to efficiently and regularly updated the dissemination of knowledge between the research community and major International and European stakeholders, national authorities and further afield. The One Health EJP will also develop sustainable programs and projects beyond the lifetime of the EJP, through the production of a Strategic Research and Innovation Agenda (2021-2030) and a European P2P One Health Cooperative Joint Initiative.";89999999,75;44998999,99;H2020-SFS-2017-1;/COFUND-EJP;AGENCE NATIONALE DE LA SECURITE SANITAIRE DE L ALIMENTATION DE L ENVIRONNEMENT ET DU TRAVAIL;FR;"STATNI ZDRAVOTNI USTAV;ISTITUTO ZOOPROFILATTICO SPERIMENTALE DELLA LOMBARDIA E DELL'EMILIA ROMAGNA BRUNO UBERTINI;BUNDESINSTITUT FUER RISIKOBEWERTUNG;FOLKEHELSEINSTITUTTET;TARTU ULIKOOL;VETERINAERINSTITUTTET - NORWEGIAN VETERINARY INSTITUTE;NATIONAL UNIVERSITY OF IRELAND GALWAY;THE SECRETARY OF STATE FOR ENVIRONMENT, FOOD AND RURAL AFFAIRS;INSTITUT SCIENTIFIQUE DE SANTE PUBLIQUE;ROBERT KOCH-INSTITUT;FRIEDRICH LOEFFLER INSTITUT - BUNDESFORSCHUNGSINSTITUT FUER TIERGESUNDHEIT;STATENS SERUM INSTITUT;NEMZETI NEPEGESZSEGUGYI KOZPONT;ISTITUTO SUPERIORE DI SANITA;STATENS VETERINAERMEDICINSKA ANSTALT;INSTITUTUL DE IGIENA SI SANATATE PUBLICA VETERINARIA;OSTERREICHISCHE AGENTUR FUR GESUNDHEIT UND ERNAHRUNGSSICHERHEIT GMBH;INSTITUTO NACIONAL DE INVESTIGACION Y TECNOLOGIA AGRARIA Y ALIMENTARIA OA MP;Department of Health;LIVSMEDELS VERKET;PANSTWOWY INSTYTUT WETERYNARYJNY - PANSTWOWY INSTYTUT BADAWCZY;UNIVERSIDAD COMPLUTENSE DE MADRID;TEAGASC - AGRICULTURE AND FOOD DEVELOPMENT AUTHORITY;NATIONAL CENTER OF INFECTIOUS AND PARASITIC DISEASES;ASSOCIATION MED-VET-NET DE RECHERCHE SUR LES ZOONOSES;RIJKSINSTITUUT VOOR VOLKSGEZONDHEID EN MILIEU;INSTITUT PASTEUR;INSTITUTO NACIONAL DE SAUDE DR. RICARDO JORGE;ISTITUTO ZOOPROFILATTICO SPERIMENTALE DELL'ABRUZZO E DEL MOLISE G CAPORALE;VYZKUMNY USTAV VETERINARNIHO LEKARSTVI;DANMARKS TEKNISKE UNIVERSITET;CENTRUM VOOR ONDERZOEK IN DIERGENEESKUNDE EN AGROCHEMIE - CODA;INSTITUTUL NATIONAL DE CERCETARE CANTACUZINO;INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE;INSTITUTO NACIONAL DE INVESTIGAÇAO AGRARIA E VETERINARIA;VETERINAAR JA TOIDULABORATOORIUM;UNIVERSITY OF SURREY;FOLKHALSOMYNDIGHETEN;BULGARIAN FOOD SAFETY AGENCY;SCIENSANO;STICHTING WAGENINGEN RESEARCH";"CZ;IT;DE;NO;EE;IE;UK;BE;DK;HU;SE;RO;AT;ES;PL;BG;FR;NL;PT";;0;1;0;0;0;1 198335;676547;COEGSS;SIGNED;H2020-EU.1.4.1.3.;EINFRA-5-2015;H2020;Center of Excellence for Global Systems Science;2015-10-01;2018-09-30;;"Global Systems Science – GSS – is an emerging research field focused on the risks and opportunities involved in global coordination problems. Examples of global systems include the internet, financial markets, intellectual property rights, global energy use and others. Developing evidence and understanding in view of such systems and of related policies is rapidly becoming a vital challenge for modern societies. It requires capabilities for transdisciplinary work that cannot be mastered without massive use of ICT. By the nature of the problem, the relevant datasets are mostly very big, including data streams from social medi. To make things more complicated, the relevant algorithms do require the power of high-performance computing. High Performance Data Analysis (HPDA) is the key to success for GSS! A key contribution of the Center of Excellence for Global Systems Science – COEGSS – will be the development of an HPC-based framework to generate customized synthetic populations for GSS applications. By blending GSS and HPC, we will be able to provide decision makers and civil society with real-time assessments of global risks and opportunities as well as with essential background knowledge about them. This will enable the HPC industry to supply hard- and software for applications well beyond the issues to which HPC has been dedicated so far.";4469662,5;4469662,5;H2020-EINFRA-2015-1;/RIA;UNIVERSITAET POTSDAM;DE;"COSMO TECH;CONSORZIO TOP-IX - TORINO E PIEMONTE EXCHANGE POINT;INSTYTUT CHEMII BIOORGANICZNEJ POLSKIEJ AKADEMII NAUK;DIALOGIK GEMEINNUETZIGE GESELLSCHAFT FUER KOMMUNIKATIONS- UND KOOPERATIONSFORSCHUNG mbH;ATOS SPAIN SA;GCF - GLOBAL CLIMATE FORUM EV;SCUOLA IMT (ISTITUZIONI, MERCATI, TECNOLOGIE) ALTI STUDI DI LUCCA;ISTITUTO PER L'INTERSCAMBIO SCIENTIFICO;UNIVERSITAET STUTTGART;CHALMERS TEKNISKA HOEGSKOLA AB";"FR;IT;PL;DE;ES;SE";;0;1;0;0;0;1 203259;688920;REPAiR;SIGNED;H2020-EU.3.5.4.;WASTE-6b-2015;H2020;REPAiR - REsource Management in Peri-urban AReas: Going Beyond Urban Metabolism;2016-09-01;2020-08-31;;A shift towards a more circular economy is crucial to achieve more sustainable and inclusive growth. Our objective is to provide local and regional authorities with an innovative transdisciplinary open source geodesign decision support environment (GDSE) developed and implemented in living labs in six metropolitan areas. The GDSE allows creating integrated, place-based eco-innovative spatial development strategies aiming at a quantitative reduction of waste flows in the strategic interface of peri-urban areas. These strategies will promote the use of waste as a resource, thus support the on-going initiatives of the EC towards establishing a strong circular economy. The identification of such eco-innovative strategies will be based on the integration of life cycle thinking and geodesign to operationalise urban metabolism. Our approach differs from previous UM as we introduce a reversed material flow accounting to collect data accurate and detailed enough for the design of a variety of solutions to place-based challenges. The developed impact and decision models allow quantification and validation of alternative solution paths and therefore promote sustainable urban development built on near-field synergies between the built and natural environments. This will be achieved by quantifying and tracking essential resource flows, mapping and quantification of negative and positive effects of present and future resource flows, and the determination of a set of indicators to inform decision makers concerning the optimization of (re-)use of resources. The GDSE will be open source. With a budget of €5 million, REPAiR funds a consortium rich in experience in waste and resource management, spatial decision support, territorial governance, spatial planning and urban design, and has deep knowledge of the 6 case study areas. REPAiR is supported by a user board, of key stakeholders for the development of CE as well as local authorities, who are heavily involved in the GDSE testing.;5089636,25;5089636,25;H2020-WASTE-2015-two-stage;/RIA;TECHNISCHE UNIVERSITEIT DELFT;NL;"Gertz Gutsche Rümenapp - Stadtentwicklung und Mobilität GbR;BAUER UMWELT GMBH;UNIVERSITEIT GENT;GEMEENTE HAARLEMMERMEER;OLP SPOLKA Z OGRANICZONA ODPOWIEDZILNOSCIA;BAUER RESOURCES GMBH;UNIVERSITA DEGLI STUDI DI NAPOLI FEDERICO II;ARCINIEGAS LOPEZ GUSTAVO;DELTA PROJECTONTWIKKELING BV;BIOKOM Pecsi Varosuzemeltetesi es Kornyezetgazdalkodasi Nonprofit Korlatolt Felelossegu Tarsasag;OPENBARE VLAAMSE AFVALSTOFFENMAATSCHAPPIJ;MAGYAR TUDOMANYOS AKADEMIA KOZGAZDASAG- ES REGIONALIS TUDOMANYI KUTATOKOZPONT;REGIONE CAMPANIA;HAFENCITY UNIVERSITAT HAMBURG;INSTYTUT GEOGRAFII I PRZESTRZENNEGO ZAGOSPODAROWANIA IM STANISLAWA LESZCZYCKIEGO POLSKIEJ AKADEMII NAUK;INTERGEMEENTELIJKE VERENIGING VOORAFVALBEHEER IN GENT EN OMSTREKEN;STADTREINIGUNG HAMBURG AOR;JRC -JOINT RESEARCH CENTRE- EUROPEAN COMMISSION";"DE;BE;NL;PL;IT;HU";;0;1;0;0;0;1 221533;836353;RENASCENCE;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;The Role of European National Health Services in the enhancement of sustainable food systems;2019-06-01;2022-05-31;;The European food systems are unsustainable, within a Europe confronting increased environmental degradation, diet related diseases and inequality. Healthcare systems have the capacity to influence the current status quo of food systems towards sustainable means. However, sustainable food system policies are recent and yet poorly implemented within the European health Services. A lack of assessment and target setting for decision making do not ease up the process. The objective of the present proposal is to explore the food system processes related with the economic and educative channels of the European health services from a sustainable dimension and to develop the first System of Indicators that will aid up in the decision making of those processes. The (co-)generation process of the System of Indicators will be via qualitative methodology. A transdisciplinary approach will be used when using the DELPHI methodology and the panel of expert for the theoretical validation of the System of Indicator. A practical phase will also be carried out to validate the System of Indicators against real cases. Additionally, during a secondment phase, we are going to lead the process of the development of a territorial strategy on food systems in health-care within the Basque region, bridging the research into policy making through participatory-action research. The knowledge obtained in this project will be used to develop strategies to target more efficiently the sustainable goals of the United Nations 2030 agenda in Europe. The Fellow will be up-skilled (in new research skills and techniques) to advance in the development of a career path towards sustainable science, to translate her background knowledge into a continuing research environment and to build and maintain links with other researchers in sustainable food policy throughout Europe aiming to contribute to policy making and developmental strategies towards sustainable societies.;241398,72;241398,72;H2020-MSCA-IF-2018;/MSCA-IF-EF-CAR;UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA;ES;;;;0;1;0;0;0;1 196818;642018;GREEN-WIN;SIGNED;H2020-EU.3.5.1.;SC5-03b-2014;H2020;Green growth and win-win strategies for sustainable climate action;2015-09-01;2018-12-31;;The GREEN-WIN project will develop a major international transdisciplinary research collaboration to apply a solution-oriented approach targeted at increasing the understanding of links between climate action and sustainability and overcoming implementation barriers through win-win strategies. The project will critically assess where and under which conditions win-win and in particular green growth strategies work in practice and where fundamental trade-offs must be faced. We thereby focus on four critical barriers that have been identified by practitioners and policy makers. First, we develop transformative narratives highlighting opportunities in climate and sustainability action in order to contribute to overcoming cognitive barriers and empowering people. Second, we examine climate and sustainability finance policies and governance arrangements in order to contribute to overcoming financial barriers to mitigation and adaptation. Third, we substantiate the economics of green growth in order to contribute to overcoming economic and collective action barriers to de-carbonisation. Towards this end we introduce major innovations into the GEM-E3 computable general equilibrium model required to discover green growth strategies. These include developing a network-based model of technological diffusion, and introducing financial market constraints and adaptive expectations of agents. Fourth, we contribute to overcoming economic and institutional barriers through identifying win-win strategies, sustainable business models and enabling environments in three action fields of coastal zone flood risk management, urban transformations and energy poverty eradication and resilience. We embed all these activities within a sustained international dialogue involving stakeholders from policy, research, civil society and the private sector, and an open knowledge management and capacity building strategy to promote knowledge transfer and learning beyond the project lifespan.;3925012,5;3624762,5;H2020-SC5-2014-two-stage;/RIA;GCF - GLOBAL CLIMATE FORUM EV;DE;"UNIVERSITAS UDAYANA;E3-MODELLING IKE;PT SUSTAINABILITY AND RESILIENCE;UNIVERSITY OF CAPE TOWN;ASSOCIATION 2 INVESTING INITIATIVE;UNIVERSITA CA' FOSCARI VENEZIA;JAGER JILL;STICHTING DELTARES;GLOBAL GREEN GROWTH INSTITUTE;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;GROUND UP ASSOCIATION;UNIVERSITAT AUTONOMA DE BARCELONA;BOGAZICI UNIVERSITESI;UNIVERSITY COLLEGE LONDON;INSTITUTE FOR ADVANCED SUSTAINABILITY STUDIES EV;ECOLE D'ECONOMIE DE PARIS";"ID;EL;ZA;FR;IT;AT;NL;KR;UK;CH;ES;TR;DE";;0;1;0;0;0;1 217465;776681;Phusicos;SIGNED;"H2020-EU.3.5.1.2.;H2020-EU.3.5.2.";SC5-08-2017;H2020;PHUSICOS: 'According to nature' - solutions to reduce risk in mountain landscapes;2018-05-01;2022-04-30;;"PHUSICOS, meaning 'According to nature' in Greek, demonstrates how nature-based solutions (NBSs) provide robust, sustainable and cost-effective measures for reducing the risk of extreme weather events in rural mountain landscapes. Although mountains amplify risks, and even more so under extreme weather events, mountainous regions do not receive the same attention as densely populated urban areas in European disaster risk reduction plans. PHUSICOS's underlying premise is that nature itself is a source of ideas and solutions for mitigating the risk posed by climate-driven natural hazards. However, there is a lack of adequate proof of concept for NBSs to address hydro-meteorological events in rural and mountainous regions. PHUSICOS will fill the knowledge gap specifically related to NBSs for hydro-meteorological hazards (flooding, erosion, landslides and drought) by implementing NBSs at several European case study sites. These sites comprise 3 large-scale demonstrator sites Italy, Frane/Spain/Andorra and Norway; and 2 small-scale complementary concept cases in Austria and Germany. The three demonstrator sites are representative of hydro-meteorological hazards, vegetation, topography and infrastructure throughout rural and mountainous regions in Europe. They have already guaranteed external financing and are currently in the process of implementing disaster risk reduction measures that are open to broader implementation of NBSs through the application of the PHUSICOS key innovation actions. The concept cases will be used for testing innovative ideas at local scale. PHUSICOS relies on a transdisciplinary consortium of 15 partners from seven European Countries, with expertise from public authorities, research institutes and universities to develop innovative actions on five fronts: technical, service, governance, learning arena and product innovations. PHUSICOS will also utilise the experience of three international partners and results of European research projects.";9633000;9472200;H2020-SC5-2017-TwoStage;/IA;STIFTELSEN NORGES GEOTEKNISKE INSTITUTT;NO;"OPPLAND FYLKESKOMMUNE;UNIVERSITA DEGLI STUDI DI SIENA;AGENCE TER;UNIVERSITE DE GENEVE;UNIVERSITAT WIEN;TECHNISCHE UNIVERSITAET MUENCHEN;CONSORCIO DE LA COMUNIDAD DE TRABAJO DE LOS PIRINEOS;UNIVERSITA DEGLI STUDI DI NAPOLI FEDERICO II;PARIS-LODRON-UNIVERSITAT SALZBURG;BUREAU DE RECHERCHES GEOLOGIQUES ET MINIERES;INTERNATIONALES INSTITUT FUER ANGEWANDTE SYSTEMANALYSE;EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH;CENTRO DE INVESTIGACION ECOLOGICA YAPLICACIONES FORESTALES CONSORCIO;RISQUES ET DEVELOPPEMENT;AUTORITA DI BACINO DISTRETTUALE";"NO;IT;FR;CH;AT;DE;ES";;0;1;0;0;0;1 200383;676754;ALTERFOR;SIGNED;H2020-EU.3.2.;ISIB-04b-2015;H2020;Alternative models and robust decision-making for future forest management;2016-04-01;2020-09-30;;"European forests are expected to provide a broad range of ecosystem services (ES). This capacity is however threatened by the uncertainties of climate change, the complex dynamics of evolving global markets and the pressures for increased use of bioenergy. Such challenges cannot be effectively addressed with an uncritical regional or national commitment to traditional forest management models (FMMs), as these are unlikely to ensure the sustained long-term provisioning of desired ES, let alone their optimised delivery. ALTERFOR’s goal is thus to facilitate the implementation of FMMs better suited to meeting the challenges of the 21st century by: (1) Identifying and developing FMMs robust in their capacity to deliver ES and overcome projected socio-ecological risks and uncertainties; (2) Assessing the impact of different FMM combinations in terms of resultant ES baskets on the European and landscape level, and (3) Facilitating the implementation of desired FMMs and improving cross-national knowledge transfer regarding their benefits, costs, management, and utilization. The project will involve a consortium of 19 organisations from nine countries chosen due to their possession of the transdisciplinary expertise necessary to achieve these objectives, and for ensuring an encompassing representation of Europe’s socio-economic conditions and prevailing forest management paradigms. Based on carefully designed case studies, the consortium will make sure realistic models of forest owner behaviour are employed; guarantee the involvement of forest stakeholders throughout the project; anchor the desired FMMs to relevant forest actors; and help disseminate project findings to local, national and European stakeholders. The main long-term impact of ALTERFOR is the implementation of FMMs that secure the capacity of Europe’s forests to continue providing a balanced ES basket that societies will depend upon over the coming century.";3999998,75;3999998,75;H2020-ISIB-2015-2;/RIA;SVERIGES LANTBRUKSUNIVERSITET;SE;"TECHNICKA UNIVERZITA VO ZVOLENE;UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN;FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.;TECHNISCHE UNIVERSITAET MUENCHEN;GEORG-AUGUST-UNIVERSITAT GOTTINGENSTIFTUNG OFFENTLICHEN RECHTS;INSTITUTO SUPERIOR DE AGRONOMIA;MINISTRY OF ENVIRONMENT AND FORESTRY GENERAL DIRECTORATE OF FORESTRY;UNIVERSITA DEGLI STUDI DI PADOVA;KARADENIZ TEKNIK UNIVERSITESI;COILLTE TEORANTA;SODRA SKOGSAGARNA EKONOMISK FORENING;VALSTYBES IMONES VALSTYBINIU MISKU UREDIJOS;INTERNATIONALES INSTITUT FUER ANGEWANDTE SYSTEMANALYSE;AFVS - ASSOCIACAO FLORESTAL DO VALE DO SOUSA;VYTAUTO DIDZIOJO UNIVERSITETAS;WAGENINGEN UNIVERSITY;DEUTSCHER FORSTVEREIN EV;ETIFOR SRL;ALEKSANDRO STULGINSKIO UNIVERSITETAS;JRC -JOINT RESEARCH CENTRE- EUROPEAN COMMISSION";"SK;IE;DE;PT;TR;IT;SE;LT;AT;NL;BE";;0;1;0;0;0;1 220757;828753;BoostCrop;SIGNED;H2020-EU.1.2.1.;FETOPEN-01-2018-2019-2020;H2020;Boosting Crop Growth using Natural Product and Synthesis Enabled Solar Harvesting;2019-01-01;2022-12-31;;"Cold and freezing stress are important constraints for crops and for horticulture. BoostCrop seeks to reduce such stress by an invention called 'molecular heaters'. These are nature-inspired molecules that absorb solar radiation and convert it to heat energy. The invention would reduce yield losses due to cold stress, extend growth seasons and the geographical locations suitable for agriculture, increase crop yield at high crop density and, concomitantly, reduce greenhouse energy costs. BoostCrop strives to increase food production to feed a continuously growing population, thus tackling a major European and Global Challenge in Food Security. The multidisciplinary research programme outlined in BoostCrop will demonstrate how intrinsic molecular processes that underlie energy transfer, and which occur on timescales of tens of trillionths of a second, can be manipulated such that macroscopic properties are impacted. The targets of the research programme include: (1) applying state-of-the-art experiments and theory to track and understand, in unprecedented detail, energy flow in targeted, nature-inspired molecules; (2) manipulating this energy flow through chemical modification; and (3) developing a suite of molecules to suit the needs of crop growth in the field and under protected (greenhouse) conditions. These molecules will then be applied to crops through an aqueous foliar spray. The proposed research programme offers a transdisciplinary and synergistic approach to developing, and understanding the properties of novel photon-to-molecule heaters. The combined expertise of 6 universities (and staff spanning Chemistry, Physics and Biology), one government institute and an SME with an outstanding track record for developing sustainable agro-technologies will ensure that the longterm vision of BoostCrop, to develop molecular heaters for use in a foliar spray, are met, thereby contributing significantly to Europe’s future technological and Food Security.";4940403,75;4940403,75;H2020-FETOPEN-2018-2019-2020-01;/RIA;THE UNIVERSITY OF WARWICK;UK;"BUNDESINSTITUT FUER RISIKOBEWERTUNG;PLANTRESPONSE BIOTECH SL;STICHTING KATHOLIEKE UNIVERSITEIT;INSTITUT DES SCIENCES ET INDUSTRIES DU VIVANT ET DE L'ENVIRONNEMENT - AGRO PARIS TECH;UNIVERSITY OF BRISTOL;UNIVERSITE D'AIX MARSEILLE;UNIVERSITEIT VAN AMSTERDAM";"DE;ES;NL;FR;UK";;0;1;0;0;0;1 216089;776866;RECONECT;SIGNED;"H2020-EU.3.5.1.2.;H2020-EU.3.5.2.";SC5-08-2017;H2020;RECONECT- Regenarating ECOsystems with Nature-based solutions for hydro-meteorological risk rEduCTion;2018-09-01;2023-08-31;;RECONECT aims to contribute to European reference framework on Nature Based Solutions (NBS) by demonstrating, referencing and upscaling large scale NBS and by stimulating a new culture for 'land use planning' that links the reduction of risks with local and regional development objectives in a sustainable way. To do that, RECONECT draws upon the network of carefully selected Demonstrators and Collaborators that cover a range of local conditions, geographic characteristics, governance structures and social/cultural settings to successfully upscale NBS throughout Europe and Internationally. The RECONECT consortium is a transdisciplinary partnership between researchers, industry partners (SMEs and large consultancies) and responsible agencies at the local and watershed/regional level dedicated to achieve the desired outcomes of the project.;15412579,48;13520689,64;H2020-SC5-2017-TwoStage;/IA;STICHTING IHE DELFT INSTITUTE FOR WATER EDUCATION;NL;"STRANE INNOVATION SAS;AMPHI INTERNATIONAL APS;INTER ACT INDUSTRIAL AUTOMATION BV;THE UNIVERSITY OF EXETER;NATIONAL CHENG KUNG UNIVERSITY;HYDRO AND AGRO INFORMATICS INSTITUTE;FREIE UND HANSESTADT HAMBURG;UNIVERSITE DE NICE SOPHIA ANTIPOLIS;TECHNISCHE UNIVERSITAT HAMBURG;HYDROLOGIC RESEARCH BV;HELMHOLTZ-ZENTRUM FUR UMWELTFORSCHUNG GMBH - UFZ;ODENSE KOMMUNE;FACULTY OF CIVIL ENGINEERING;STIFTELSEN THE STOCKHOLM ENVIRONMENT INSTITUTE;PREDUZECE ZA PROJEKTOVANJE, INZENJERING I KONSALTING IWA CONSALT DOO, BEOGRAD (VRACAR);Black Sea - Danube Association for Research and Development;EIDGENOESSISCHE ANSTALT FUER WASSERVERSORGUNG ABWASSERREINIGUNG UND GEWAESSERSCHUTZ;PANSTWOWE GOSPODARSTWO WODNE WODY POLSKIE;CONSIGLIO NAZIONALE DELLE RICERCHE;PRONING DHI DOO ZA PROJEKTIRANJE USLUGE I TRGOVINU;Hydrometeorological Innovative Solutions;DANMARKS TEKNISKE UNIVERSITET;EUROPEJSKIE REGIONALNE CENTRUM EKOHYDROLOGII POLSKIEJ AKADEMII NAUK;GISIG GEOGRAPHICAL INFORMATION SYSTEMS INTERNATIONAL GROUP ASSOCIAZIONE;ENTE PARCO DI PORTOFINO;AARHUS KOMMUNE;RAMBOLL DANMARK A/S;UNIVERSITAET INNSBRUCK;MONASH UNIVERSITY MALAYSIA SDN BHD;EUROSENSE BELFOTOP;TAUW BV;INTERNATIONAL WATER ASSOCIATION;REGIONAL ADMINISTRATION VARNA;Ag?ncia Catalana de l'Aigua";"FR;DK;NL;UK;TW;TH;DE;RS;SE;BG;CH;PL;IT;HR;ES;AT;MY;BE";;0;1;0;0;0;1 215403;795937;WONT-HATE;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Online Hate against European Women Leaders: a Corpus-Assisted Multimodal Critical Analysis;2019-03-01;2021-02-28;;"Today’s digital media have a strong potential to strengthen women’s participation in political and institutional processes, but have also opened up new channels for gendered attacks against women advancing their way in the public sphere. WONT-HATE investigates phenomena of online misogyny, such as gender-based hate speech, rape threats and image-based sexual harassment, against highly visible, political and institutional figures in Europe. More specifically, WONT-HATE maps the multimodal discursive and rhetorical strategies of online hate against women in politics across four different linguistic landscapes and political cultures in Europe, namely Italy, Spain, France and the U.K. WONT-HATE is characterized by a multimodal critical discursive approach to cyberhate, entailing a quantitative and qualitative investigation of a corpus of Youtube videos and relative user-generated comments. WONT-HATE is to contribute to the current debate on the use of social media data for social research, providing new critical theoretical perspectives as well as a transdisciplinary methodology for data selection and collection and for the contextualization of the new dynamics of digital interaction. Two secondments, at the University of Vienna and Newcastle University, further contribute to establishing a dialogue on cutting-edge social media approaches across Europe. WONT-HATE is also to yield an open access database of online misogyny speech, encompassing its lexico-syntactic and discursive features in Italian, Spanish, French and English, to foster academic research and the advancement of software solutions to the issue. Exploring discourse as social practice, and refusing to treat the ‘online’ and the ‘offline’ as separate and independent realms, WONT-HATE tackles timely issues of digital security, gender-based violence and gender equality, in line with the gender-related objectives of the Horizon 2020 Programme and the EU Strategic Engagement for Gender Equality 2016-2019.";158121,6;158121,6;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;UNIVERSIDAD DE NAVARRA;ES;;;;0;1;0;0;0;1 216086;776783;URBiNAT;SIGNED;"H2020-EU.3.5.2.1.;H2020-EU.3.5.2.3.;H2020-EU.3.5.1.2.;H2020-EU.3.5.1.3.;H2020-EU.3.5.2.2.";SCC-02-2016-2017;H2020;URBiNAT - Healthy corridors as drivers of social housing neighbourhoods for the co-creation of social, environmental and marketable NBS;2018-06-01;2023-05-31;;"URBiNAT focuses on the regeneration and integration of deprived social housing urban developments through an innovative and inclusive catalogue of Nature-Based Solutions (NBS), ensuring sustainability and mobilising driving forces for social cohesion. Interventions focus on the public space to co-create with citizens new urban, social and nature-based relations within and between different neighbourhoods. Taking the full physical, mental and social well-being of citizens as its main goal, URBiNAT aims to co-plan a healthy corridor as an innovative and flexible NBS, which itself integrates a large number of micro NBS emerging from community-driven design processes. URBiNAT consists of a worldwide consortium of academic and business partners around 7 European cities (Porto, Nantes and Sofia as ‘frontrunners’; Siena, Nova Gorica, Brussels and H?je-Taastrup as followers), that will act as living laboratories to implement healthy corridor solutions. The cities will be supported by local partners, associations and research centres, and by Europe-wide centres, universities and companies. These will develop a participatory process, an NBS catalogue and a healthy corridor, while monitoring impacts, disseminating and marketing results. Together, they form an inclusive community of practice (CoP), collaborating with partners from Iran and China, and NBS observers located in Brazil, Oman, Japan and a Chinese city, bringing experiences and an international dimension to the project. Partners will contribute their innovative NBS experience deployed through an array of transdisciplinary knowledge, methodologies and tools, as nature-based solutions. This will be supplmented by ‘smart’ digital tools, citizen engagement, solidarity and social economy initiatives, social innovation for value-generation, incubation for business development and capacity building, and ICT governance platforms. The social, economic and urban impacts will be measured and replicated by URBiNAT Observatory.";13742228,64;13019300;H2020-SCC-NBS-2stage-2017;/IA;CENTRO DE ESTUDOS SOCIAIS;PT;"CAMARA MUNICIPAL DO PORTO;Nantes Métropole;UNIVERSITEIT ANTWERPEN;LIBERA UNIVERSITA DI LINGUE E COMUNICAZIONE IULM;FORENINGEN IKED;TEKNOLOGISK INSTITUT;MESTNA OBCINA NOVA GORICA;FONDAZIONE GIANGIACOMO FELTRINELLI;ITEMS INTERNATIONAL SARL;MUNICIPALITY OF SOFIA;COMUNE DI SIENA;IRAN CHAMBER OF COMMERCE, INDUSTRIES, MINES AND AGRICULTURE;UNIVERSIDADE DE COIMBRA;SLA AS;HOCHSCHULE OSTWESTFALEN-LIPPE;UNIVERSITET PO ARCHITEKTURA STROITELSTVO I GEODEZIJA;CMPH - DOMUSSOCIAL - EMPRESA DE HABITACAO E MANUTENCAO DO MUNICIPIO DO PORTO;CHINA SMART CITY PLANNING & DESIGN RESEARCH INSTITUTE CO;CITY FACILITATORS IVS;VILLE DE BRUXELLES;UNIVERZA V NOVI GORICI;INSTITUT D'ARQUITECTURA AVANCADA DE CATALUNYA;GIVE U DESIGN ART LDA;ICETA INSTITUTO DE CIENCIAS, TECNOLOGIAS E AGROAMBIENTE DA UNIVERSIDADE DO PORTO;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;NEW GROWING SYSTEMS SL;HOJE-TAASTRUP KOMMUNE";"PT;FR;BE;IT;SE;DK;SI;BG;IR;DE;CN;ES";;0;1;0;0;0;1 202430;706346;INVISIBLE WATERS;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-GF;H2020;Visualizing aquifers: sustainable water use in the Atacama Desert and beyond;2017-01-01;2019-06-30;;"Billions of people rely for their everyday existence on aquifers. The invisibility of these waters, however, poses formidable challenges for those who rely on them: locating, measuring and controlling aquifers is complex and precarious, yet of utmost importance for human survival in many parts of the world. The overall aim of the proposed project is to explore the vital connections between humans and aquifers in everyday life. Building on trans-disciplinary studies that consider water as the contested nexus of social and political affairs, this project explores groundwater as both mediating and generating diverse ‘groundwater practices’: as an invisible resource, groundwater requires visualization; as an underground supply, it calls for innovative extractive techniques; as a finite good, groundwater needs to be regulated and controlled; and as a practical everyday resource, it sustains irrigation, sanitation, and human consumption. Through ethnographic fieldwork in Atacama Desert of Northern Chile, this project will develop an analytical framework to understand how social relations are affected by various groundwater practices. The proposed research will explore such practices with a focus on the effects that the visualization of aquifers has on socio-economic and eco-political inequalities. Through transdisciplinary training at the Universidad Católica del Norte, I will strengthen methodological skills to study the groundwater practices of indigenous communities, hydro-geologists and state administrators. I will transfer the acquired skills to the UNESCO-IHE Institute for Water Education, where I will strengthen understandings of the dynamics among groundwater practices, power, and culture, providing trans-disciplinary input for policymakers engaged in the design and realization of the Sustainable Development Goals. Findings will be disseminated among policymakers, academics, and broader audiences concerned with environmental sustainability.";190862,1;190862,1;H2020-MSCA-IF-2015;/MSCA-IF-GF;STICHTING IHE DELFT INSTITUTE FOR WATER EDUCATION;NL;;;;0;1;0;0;0;1 216610;776608;AXIS;SIGNED;H2020-EU.3.5.1.;SC5-30-2017;H2020;Assessment of Cross(X)-sectoral climate Impacts and pathways for Sustainable transformation;2018-01-01;2022-12-31;;"The AXIS consortium is set up to enhance integration of an array of research disciplines connected to climate research around the common goal to enhance the assessment of potential impacts of climate change on the bio-physical systems and human society. To this end AXIS plans to launch and implement a single transnational call – funded by 11 European research funders. Through an open process AXIS has developed three topics for this call. Each topic is intended to enhance collaboration across typical community borders: between different sectoral views of climate impacts as well as between bio-physical climate impacts and socio-economic effects. For all topics stakeholder engagement is given a high relevance in the call, thus representing another dimension of interaction across boundaries: interaction of the science community with end-users (stakeholders) of the created knowledge (transdisciplinarity). The three anticipated research areas (topics) are: (1) Cross-sectoral and cross-scale climate change impact assessments; (2) Integration of biophysical climate change impacts estimates with economic models; (3) Developing pathways to achieve the long-term objectives of the Paris Agreement, taking into account interactions with SDGs closely linked to SDG 13 (“climate action”). The AXIS consortium is deeply embedded in JPI Climate and aims to implement elements of its Strategic Research & Innovation Agenda. JPI Climate and the ERA-NET promoting Climate Services ERA4CS include a number of additional activities. Therefore within this proposal no addition activities are planned. Close partnership of the AXIS consortium and JPI Climate with other key international initiatives (Belmont Forum, GFCS, Future Earth, UN PROVIA, Copernicus) will be sought in order to continue to work against fragmentation of disciplines and geographies in climate science. In this respect a close connection with the parallel CSA proposal SINCERE is planned.";15783582;5208582,06;H2020-SC5-2017-OneStageB;/ERA-NET-Cofund;DEUTSCHES ZENTRUM FUER LUFT - UND RAUMFAHRT EV;DE;"NEDERLANDSE ORGANISATIE VOOR WETENSCHAPPELIJK ONDERZOEK;CENTRUL PROIECTE INTERNATIONALE;MINISTERIO DE ECONOMIA Y COMPETITIVIDAD;FORSKNINGSR?DET FÖR MILJÖ, AREELLA NÄRINGAR OCH SAMHÄLLSBYGGANDE;NORGES FORSKNINGSRAD;ENVIRONMENTAL PROTECTION AGENCY OF IRELAND;SERVICE PUBLIC FEDERAL DE PROGRAMMATION POLITIQUE SCIENTIFIQUE;AGENCE NATIONALE DE LA RECHERCHE;FONDS NATIONAL DE LA RECHERCHE SCIENTIFIQUE;OESTERREICHISCHE FORSCHUNGSFOERDERUNGSGESELLSCHAFT MBH";"NL;MD;ES;SE;NO;IE;BE;FR;AT";;0;1;0;0;0;1 203389;689925;SafeWaterAfrica;SIGNED;H2020-EU.3.5.4.;WATER-5c-2015;H2020;Self-Sustaining Cleaning Technology for Safe Water Supply and Management in Rural African Areas;2016-06-01;2019-11-30;https://safewaterafrica.eu;"This project focuses on a major challenge in African countries: In the 15 sub-Saharan African countries 108 million people have limited or even no access to clean water. The SafeWaterAfrica project will research and develop an autonomous and decentralized water treatment system for rural and peri-urban areas which is highly efficient in the degradation of harmful pollutants and at the same time very effective in killing microbiological contaminants. The system will be designed to provide 300 people in rural areas. With a market penetration of 3000 systems the project has the potential to supply 900,000 people within app. four years after the end of the project. The project includes capacity building and business development so that system ownership and responsibility are in the hands of the local rural communities. The joint European-African development will result in a low-cost solution easy to handle and operate. It will take into account the specific cultural aspects of the region and will be designed for operation with local staff and in the responsibility of local communities or local water service providers, respectively. These “Made in Africa” systems will therefore have a high level of acceptance in the rural areas which promotes the implementation of the technology. Ten transdisciplinary partners from Europe and Africa, assisted by eight enterprises and organisations in the Advisory Board, will work jointly over a project duration of 42 months to adapt a specific European water treatment technology into an African water treatment system solution. Besides, SafeWaterAfrica will generate the technological basis for innovative business models related to the development of water treatment products, which are produced, installed, operated and maintained in Africa. The resulting creation of new jobs will contribute to the social well-being and will promote economic growth in the rural and peri-urban areas of the southern African countries.";2989998,13;2989998,13;H2020-WATER-2015-two-stage;/RIA;FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.;DE;"CONDIAS GMBH;ADVANCE CALL PTY LTD;COUNCIL FOR SCIENTIFIC AND INDUSTRIAL RESEARCH;TSHWANE UNIVERSITY OF TECHNOLOGY;UNIVERSIDAD DE CASTILLA - LA MANCHA;SALOMON LDA;VIRTUAL CONSULTING ENGINEERS VCE;STELLENBOSCH UNIVERSITY;UNIVERSITA DEGLI STUDI DI FERRARA";"DE;ZA;ES;MZ;IT";;0;1;0;0;0;1 210048;741402;NewHoRRIzon;SIGNED;H2020-EU.5.f.;SwafS-09-2016;H2020;Excellence in science and innovation for Europe by adopting the concept of Responsible Research and Innovation;2017-05-01;2021-04-30;;The Project “Excellence in science and innovation for Europe by adopting the concept of Responsible Research and Innovation (NewHoRRIzon)” sets out to promote the acceptance of RRI in Horizon 2020 (H2020) and beyond. It will work out the conceptual and operational basis to fully integrate RRI into European and national research and innovation (R&I) practice and funding. In order to accomplish this goal, NewHoRRIzon will establish altogether 18 Social Labs that cover all sections of H2020. Together with a wide-ranging group of R&I stakeholders, in these Social Labs, NewHoRRIzon will co-create tailor-made pilot actions that will stimulate an increased use and acceptance of RRI across H2020 and each of its parts. These pilot actions will address a variety of R&I actors such as academia, business, non-university research institutes, research funding organisations, policy-makers on European, Member State and global level, civil society organisations (CSOs) and the general and specific public(s) as they arise from technological controversies. Ultimately, the pilot actions to be developed and tested in the Social Labs will contribute to R&I projects that fully recognise the significance of RRI. NewHoRRIzon will stimulate learning about how to accomplish RRI in H2020 and beyond in its Social Labs, in two cross-sectional workshops and two transdisciplinary conferences. It will conceptualise and operationalise a Society Readiness Level (SRL) for R&I that focuses on the alignment between the processes and products of R&I on the one hand, and broader societal demands and expectations on the other. Finally, NewHoRRIzon will use a variety of target-group specific strategies to disseminate best practises to promote acceptance of RRI across H2020 and generate long-term impact. For that it will use existing spaces and networks as well as create new ones.;6799943;6799943;H2020-SwafS-2016-1;/CSA;INSTITUT FUER HOEHERE STUDIEN - INSTITUTE FOR ADVANCED STUDIES;AT;"AARHUS UNIVERSITET;VEREINIGUNG DEUTSCHER WISSENSCHAFTLER EV;UNIVERSITEIT LEIDEN;SIHTASUTUS EESTI TEADUSAGENTUUR;COLEGIO MAYOR DE NUESTRA SENORA DELROSARIO CORPORACION SIN ANIMO DE LUCRO;Teknologian tutkimuskeskus VTT Oy;FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.;FUNDACION TECNALIA RESEARCH & INNOVATION;THE UNIVERSITY OF THE WEST INDIES U WI*;FONDATION NATIONALE DES SCIENCES POLITIQUES;MINISTERIE VAN ECONOMISCHE ZAKEN EN KLIMAAT;TECHNOLOGICKA AGENTURA CESKE REPUBLIKY;ZENTRUM FUR SOZIALE INNOVATION GMBH;WAGENINGEN UNIVERSITY;EUROSCIENCE ASSOCIATION;GENOK - SENTER FOR BIOSIKKERHET;UNIVERSITEIT VAN AMSTERDAM;OESTERREICHISCHE FORSCHUNGSFOERDERUNGSGESELLSCHAFT MBH";"DK;DE;NL;EE;CO;FI;ES;JM;FR;CZ;AT;NO";;0;1;0;0;0;1 209720;723491;SABRE;SIGNED;H2020-EU.3.4.;MG-1.1-2016;H2020;Shape Adaptive Blades for Rotorcraft Efficiency;2017-06-01;2020-11-30;;"Shape Adaptive Blades for Rotorcraft Efficiency (SABRE) will develop ground-breaking new helicopter blade morphing technologies which will reduce helicopter fuel burn, CO2 and NOx emissions by 5-10%, while also reducing noise emissions. SABRE will help Europe achieve its ambitious aviation emissions goals while also sharpening its competitive edge in the rapidly growing international helicopter market. It will achieve this ambitious objective by removing one of the most fundamental limitations on helicopter performance: the need for rotor blades to have a single fixed geometry which is inherently a compromise between widely different operating conditions. SABRE envisions shape adaptive blades which can continuously change their shape to optimise performance in all conditions. SABRE has a tightly cross-linked, dual stream research approach with emissions-focused rotor performance analysis running concurrently with morphing technology development. The analysis stream will combine comprehensive rotor analysis, high-fidelity aerodynamic and structural solvers, detailed morphing mechanism models, and emissions models, creating the most detailed, transdisciplinary, and comprehensive model of its type. The technology development stream will mature a selected group of novel, beyond state-of-the-art, helicopter focused morphing concepts through a carefully considered program of modelling, design and experimental testing efforts. The achievable performance of the morphing concepts will be fed back into the emissions analysis, and the analysis stream will guide the development of the technologies towards configurations which minimize emissions. SABRE is highly ambitious in both its objectives and its approach. The project has strong industry support, and brings together the ideal consortium to achieve its objectives; with world-leading experts in rotorcraft and morphing structures backed up by a clear project plan, robust management procedures, and excellent facilities.";6033398,75;6033398,75;H2020-MG-2016-Two-Stages;/RIA;UNIVERSITY OF BRISTOL ROYAL CHARTER;UK;"SWANSEA UNIVERSITY;TECHNISCHE UNIVERSITAET MUENCHEN;DEUTSCHES ZENTRUM FUER LUFT - UND RAUMFAHRT EV;CENTRO ITALIANO RICERCHE AEROSPAZIALI SCPA;TECHNISCHE UNIVERSITEIT DELFT";"UK;DE;IT;NL";;0;1;0;0;0;1 207189;730254;EN-SUGI;SIGNED;"H2020-EU.3.5.2.3.;H2020-EU.3.5.1.2.;H2020-EU.3.5.1.3.;H2020-EU.3.5.4.;H2020-EU.3.5.2.2.";SCC-04-2016;H2020;Eranet Sustainable Urbanisation Global Initiative;2016-12-01;2021-11-30;;"Cities around the globe are struggling to meet the needs of their citizens with respect to food, energy and water. These three sectors are inextricably linked and actions in one sector more often have impacts in one or both of the others; these interacting sectors can therefore be seen as a Food-Energy-Water Nexus (FEW Nexus) of systems. The ERANET Sustainable Urbanisation Global Initiative (EN-SUGI) will bring together the fragmented research and innovation expertise across Europe and beyond to find innovative new solutions to this FEW Nexus challenge. Furthermore, by linking the activity of the Joint Programming Initiative (JPI) Urban Europe and the Belmont Forum (BF), EN-SUGI develops more resilient, applied urban solutions that bring research and innovation together from across the globe. EN-SUGI is a project that foresees the participation of 19 Funding Agencies eligible for the EU top up, 18 from JPI Urban Europe and 1 from Argentina, and 6 FAs non eligible for EU top up, under the umbrella of the Belmont forum , collaborating on a volunteer base. EN-SUGI Main objectives and impacts are: To support development of practical innovations and new collaborative research that will allow urban areas to understand and address the challenges of the Food-Energy-Water systems. (Impact = 12-14 projects funded, and 15 cities/local authorities engaged) To provide a framework for aligning R&I agendas of JPI Urban Europe and the BF,. The alignment will help foster transdisciplinary collaboration and co-creation in research and innovation, and facilitate the use of global expertise and knowledge (Impact = 24 funding organisations involved) EN-SUGI will foster development of international relationships between the different parts of the research and innovation community – to enable them to contribute to addressing those challenges and goals, while aligning them to wider, strategic initiatives, including the SRIA agenda, Future Earth and UN –Habitat.";18649260;5000053,11;H2020-SCC-NBS-1stage-2016;/ERA-NET-Cofund;UNITED KINGDOM RESEARCH AND INNOVATION;UK;"STATENS ENERGIMYNDIGHET;NEDERLANDSE ORGANISATIE VOOR WETENSCHAPPELIJK ONDERZOEK;ECONOMIC AND SOCIAL RESEARCH COUNCIL;FORSCHUNGSZENTRUM JULICH GMBH;IDRYMA PROOTHISIS EREVNAS;BUNDESMINISTERIUM FUER VERKEHR, INNOVATION UND TECHNOLOGIE;TURKIYE BILIMSEL VE TEKNOLOJIK ARASTIRMA KURUMU;JAVNA AGENCIJA ZA RAZISKOVALNO DEJAVNOST REPUBLIKE SLOVENIJE;BUNDESMINISTERIUM FUER BILDUNG UND FORSCHUNG;VALSTS IZGLITIBAS ATTISTIBAS AGENTURA;THE ARTS AND HUMANITIES RESEARCH COUNCIL;FORSKNINGSR?DET FÖR MILJÖ, AREELLA NÄRINGAR OCH SAMHÄLLSBYGGANDE;Institut pour l'Encouragement de la Recherche scientifique et de l'Innovation de Bruxelles;NARODOWE CENTRUM NAUKI;NORGES FORSKNINGSRAD;AGENCE NATIONALE DE LA RECHERCHE;Ministerio de Ciencia, Tecnología e Innovación Productiva;FONDS VOOR WETENSCHAPPELIJK ONDERZOEK-VLAANDEREN;OESTERREICHISCHE FORSCHUNGSFOERDERUNGSGESELLSCHAFT MBH";"SE;NL;UK;DE;CY;AT;TR;SI;LV;BE;PL;NO;FR;AR";;0;1;0;0;0;1 205674;726744;EXPAND;SIGNED;H2020-EU.4.;WIDESPREAD-02-2016;H2020;EXPAND - enhancing co-creation in JPI Urban Europe through widening Member State and stakeholder participation;2016-09-01;2019-02-28;;"EXPAND intends to support the implementation of the JPI Urban Europe Strategic Research and Innovation Agenda (SRIA) by (1) supporting JPI Urban Europe’s widening activities towards new countries, stakeholders and partners; and (2) focusing on the development and piloting of new instruments, framework conditions and methods for transnational and transdisciplinary cooperation. Since urban transformations to sustainable and liveable futures depends on a broad commitment and co-creation among a diverse set of actors, the identified challenge to be tackled by EXPAND is widening the community. Specifically in terms of member countries. But also in terms of stakeholder involvement in core activities. Furthermore, the challenge is also to be tackled by the development and implementation of new instruments and framework conditions that support such a co-creation and alignment of European, national and local research and innovation actions. As the basic concept for widening participation, a Stakeholder Involvement Platform (SIP) will be developed that anticipates the needs of different stakeholder groups and regions to facilitate the strategic dialogue between all stakeholder groups and implement the SRIA. The SIP relates to new approaches in programme management, alignment of national programmes, strategies and policies as well as new instruments for research funding and new formats for dissemination and exploitation of research results. Strategic relationships will be developed with national, European and international organisations and special attention will be given to reach out and mobilise actors in Widening countries. Two JPI Urban Europe Conferences will be organised to position JPI Urban Europe in the wider European Research and Innovation community and a self-monitoring system will be developed and tested to allow a consistent monitoring of JPI Urban Europe activities.";1499998,75;1499998,75;H2020-WIDESPREAD-02-2016-JPI-UrbanEurope;/CSA;NEDERLANDSE ORGANISATIE VOOR WETENSCHAPPELIJK ONDERZOEK;NL;"AIT AUSTRIAN INSTITUTE OF TECHNOLOGY GMBH;FORSCHUNGSZENTRUM JULICH GMBH;IDRYMA PROOTHISIS EREVNAS;Unitatea Executiva pentru Finantarea Invatamantului Superior, a Cercetarii, Dezvoltarii si Inovarii;MINISTERO DELL'ISTRUZIONE, DELL'UNIVERSITA' E DELLA RICERCA;JAVNA AGENCIJA ZA RAZISKOVALNO DEJAVNOST REPUBLIKE SLOVENIJE;VALSTS IZGLITIBAS ATTISTIBAS AGENTURA;AGENZIA NAZIONALE PER LE NUOVE TECNOLOGIE, L'ENERGIA E LO SVILUPPO ECONOMICO SOSTENIBILE;NARODOWE CENTRUM NAUKI;UNITED KINGDOM RESEARCH AND INNOVATION;IQ SAMHALLSBYGGNAD AB;STICHTING PLATFORM31;The Technology Strategy Board;INSTITUT FRANCAIS DES SCIENCES ET TECHNOLOGIES DES TRANSPORTS, DE L'AMENAGEMENT ET DES RESEAUX;OESTERREICHISCHE FORSCHUNGSFOERDERUNGSGESELLSCHAFT MBH;FUNDACAO PARA A CIENCIA E A TECNOLOGIA";"AT;DE;CY;RO;IT;SI;LV;PL;UK;SE;NL;FR;PT";;0;1;0;0;0;1 200242;677363;SALSA;SIGNED;H2020-EU.3.2.;SFS-18-2015;H2020;Small farms, small food businesses and sustainable food security;2016-04-01;2020-03-31;;"SALSA will assess the role of small farms and small food businesses in delivering a sustainable and secure supply of affordable, nutritious and culturally adequate food. SALSA will identify the mechanisms which, at different scales, can strengthen the role of small farms in food systems and thereby support sustainable food and nutrition security (FNS). By considering a gradient of 30 reference regions in Europe and in Africa, we will obtain a differentiated understanding of the role of small farms and small food businesses in very differently structured food systems and situations. SALSA will elaborate and implement a transdisciplinary, multi-scale approach that builds on and connects relevant theoretical and analytical frameworks within a food systems approach, and that uses qualitative, consultative and quantitative methods. We will also test a new combination of data-based methods and tools (including satellite technologies) for rigorously assessing in quantitative terms the interrelationships between small farms, other small food businesses and FNS, paying particular attention to limiting and enabling factors. SALSA will use participatory methods, at regional level, and establish a more global Community of Practice and multi-stakeholder learning platform, based on FAO’s TECA online communication and learning platform. The SALSA consortium, and the joint learning and close cooperation, have both been designed with the EU - Africa dialogue in mind. Responding to the call we will unravel the complex interrelationships between small farms, small food businesses and FNS, and unfold the role played by small farms in (a) the balance between the different dimensions of sustainability, (b) maintaining more diverse production systems, (c) supporting the urban/rural balance in terms of labour and (d) in facilitating territorial development in countries facing a strong rural population growth.";4958172,5;4958172,5;H2020-SFS-2015-2;/RIA;UNIVERSIDADE DE EVORA;PT;"FOOD AND AGRICULTURE ORGANIZATION OF THE UNITED NATIONS FAO;THE JAMES HUTTON INSTITUTE;INTERNATIONAL CENTRE FOR RESEARCH IN AGROFORESTRY;UNIVERSITY FOR DEVELOPMENT STUDIES;UNIWERSYTET ROLNICZY IM. HUGONA KOLLATAJA W KRAKOWIE;AFRICAN CENTRE FOR TECHNOLOGY STUDIES;Coldiretti;INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE DE TUNISIE;UNIVERSIDADE DE CABO VERDE;International Institute for Environment and Development;STIFTELSEN RURALIS INSTITUTT FOR RURAL- OG REGIONALFORSKNING;UNIVERSITA DI PISA;NODIBINAJUMS BALTIC STUDIES CENTRE;AGRICULTURAL UNIVERSITY OF ATHENS;HIGHCLERE CONSULTING SRL;UNIVERSITAT POLITECNICA DE VALENCIA";"IT;UK;KE;GH;PL;TN;CV;NO;LV;EL;RO;ES";;0;1;0;0;0;1 196880;648810;Integrating Turkish;SIGNED;H2020-EU.1.1.;ERC-CoG-2014;H2020;Beyond East and West: Developing and Documenting an Evolving Transcultural Musical Practice;2015-09-01;2020-08-31;;"For composers in Turkey today, the urge to integrate the beauties of Turkey’s rich musical heritage into contemporary concert music has become almost an imperative. But differences in tuning, texture, and between oral and notated orientations to performance have presented seemingly intractable obstacles. This project systematises practical processes essential for the creation of a new, East-West strand of contemporary music and opera. It initiates cutting-edge research workshops in Istanbul, Holland and the UK to: 1. Train top-level traditional instrumentalists and singers in Turkey effectively to perform a new repertoire; 2. Train top professional Western singers in non-Western techniques and nuances of vocal production; 3. Develop approaches for modelling such music's impacts on Turkish and Western musicians’ adaptive processes in rehearsal and performance, and diverse audiences’ perceptions of such music; 4. Create an ensemble interface (including newly designed instruments) to increase capacity for merging sounds beyond levels now achievable; 5. Produce groundbreaking studies on timbre to provide new insights into how sound is produced; 6. Establish a new template for mapping Eastern and Western tuning systems onto one another. This research, together with an orchestration manual for Turkish sounds will comprise the core of a published (CUP) team-authored e-book, Integrating Turkish Instruments and Voices into Contemporary Music (ITI), with included audio and visual examples linked as an online resource. Looking further, this project’s multi-modal, transdisciplinary approach also suggests a model for probing how the ‘free play’ of the imagination (Kant) possible within processes of art and its creation can provide metaphors towards understanding one of the most urgent and compelling issues of our time: how to transcend cultural barriers (real or imagined) that exist today.";2000000;2000000;ERC-2014-CoG;/ERC-COG;UNIVERSITY OF BRISTOL ROYAL CHARTER;UK;"ISTANBUL TEKNIK UNIVERSITESI;BATH SPA UNIVERSITY";"TR;UK";;0;1;0;0;0;1 197443;664932;NUCLEUS;SIGNED;H2020-EU.5.c.;ISSI-5-2014;H2020;NUCLEUS - New Understanding of Communication, Learning and Engagement in Universities and Scientific Institutions;2015-09-01;2019-08-31;;"NUCLEUS develops, supports and implements inclusive and sustainable approaches to Responsible Research and Innovation within the governance and culture of research organisations in Europe. A major goal of the transdisciplinary project will be to stimulate research and innovation which continuously reflects and responds to societal needs. In order to achieve a multifaceted and cross-cultural New Understanding of Communication, Learning and Engagement in Universities and Scientific Institutions, 26 renowned institutions from 15 countries, among them leading representatives of 14 universities, will collaboratively identify, develop, implement and support inclusive and sustainable approaches to RRI. For a mutual learning and exchange process, the project will reach out beyond the European Research Area by including renowned scientific institutions in China, Russia and South Africa. Within a 4-year timeframe NUCLEUS will systematically uncover and analyse structural and cultural obstacles to RRI in scientific institutions. The partners will collaboratively develop innovative approaches to overcome these barriers. The project is expected to lead to an applicable ‘RRI DNA’, providing practical guidelines for higher education institutions and funding agencies across Europe and beyond. This ‘DNA’ will form the basis for the ‘NUCLEUS Living Network’, an alliance to ensure sustainability of the approach beyond the project timeline. By offering new academic insights and practical recommendations derived from 30 ‘RRI test beds’, NUCLEUS will contribute to the debate on science policies both on a national and European level, including the future design of HORIZON 2020 and the European Research Area (ERA).";3993632,5;3993632,5;H2020-ISSI-2014-1;/CSA;HOCHSCHULE RHEIN-WAAL-HSRW RHINE-WAAL UNIVERSITY OF APPLIED SCIENCES;DE;"EUSEA - EUROPAISCHE GESELLSCHAFT FUR WISSENSCHAFTSVERANSTALTUNGEN;L'UNION EUROPEENNE DES ASSOCIATIONSDE JOURNALISTES SCIENTIFIQUES ASSOCIATION;ELLINIKH ENOSH DHMOSIOGRAFON EPISTHMHS, SYGGRAFEON EPISTHMHS KAI EIKOINONIOLOGON EPISTHMHS ASTIKI ETAIREIA;THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN;COMUNAUTE D'UNIVERSITES ET ETABLISSEMENTS UNIVERSITE DE LYON;LANDESHAUPTSTADT HANNOVER;DUBLIN CITY UNIVERSITY;GENOME RESEARCH LIMITED;MATEMATICKI INSTITUT SANU, BEOGRAD;PSIQUADRO SOCIETA COOPERATIVA;Nottingham City Council;NATIONAL RESEARCH FOUNDATION;UNIVERSITEIT TWENTE;STADT BOCHUM;CHINA RESEARCH INSTITUTE FOR SCIENCE POPULARIZATION;RUHR-UNIVERSITAET BOCHUM;BEIJING DEVELOPMENT CENTER OF POPULAR SCIENCE;WISSENSCHAFT IM DIALOG GGMBH;THE NOTTINGHAM TRENT UNIVERSITY;UNIVERSITA TA MALTA;UNIVERSITAET BIELEFELD;ILIA STATE UNIVERSITY;THE UNIVERSITY OF EDINBURGH;TECHNISCHE UNIVERSITEIT DELFT";"AT;FR;EL;UK;DE;IE;RS;IT;ZA;NL;CN;MT;GE";;0;1;0;0;0;1 213397;758529;TopATLAS;SIGNED;H2020-EU.1.1.;ERC-2017-STG;H2020;Topological Atlas: Mapping Contemporary Borderscapes;2018-06-01;2023-05-31;;"Contemporary borders operate in ways that are more complex than in the past. They have been variously conceptualised as porous, shifting and solidified. Where a border may be open for some, for others it is an impenetrable wall. Combined with the mobility of geopolitical territorial formations that operate beyond legal frameworks, such as the formation of ISIS and the situation in Europe where borders are being opened and closed against agreed treaties, the very concept of the border is being radically questioned. We need new ways to make sense of these increasingly complex spaces. This proposal aims to develop a transdisciplinary research programme for mapping, analysing and intervening in border areas in the form of a digital atlas. Topological Atlas is developed as a methodology for producing visual counter-geographies at border sites. It is ground breaking in its use of digital technologies combined with a participative approach that attends to those who are at the margins of traditional geopolitical inquiry. The project uses topology as conceptual framework and methodology to make maps that produce ‘seamless transitions’ from the space of the migrant to that of the security apparatus that creates barriers to her movement. In doing so it seeks to disrupt the cartographic norms that are being reinforced through the prevalence of GIS technology and mapping platforms such as Google Earth. It investigates forms of visual and co-produced research adapted to situations of crisis and proposes a new model for researching border areas beyond the current top-down international relations or security perspective. At the same time it acknowledges the intertwined relationship between the practice of academic inquiry, the knowledge it produces and what such knowledge can do. The project is organised around the following research question: How can mapping be used to represent borders as topological entities through the experience of those who encounter them?";1498349;1498349;ERC-2017-STG;/ERC-STG;GOLDSMITHS' COLLEGE;UK;"THE UNIVERSITY OF SHEFFIELD;UNIVERSITY OF CUKUROVA";"UK;TR";;0;1;0;0;0;1 215949;773901;UNISECO;SIGNED;H2020-EU.3.2.1.1.;SFS-29-2017;H2020;Understanding and improving the sustainability of agro-ecological farming systems in the EU;2018-05-01;2021-04-30;;The overarching objective of UNISECO is to strengthen the sustainability of EU farming systems, through co-constructing practice-validated strategies and incentives for the promotion of improved agro-ecological approaches. We will enhance the understanding of socio-economic and policy drivers and barriers for further development and implementation of agro-ecological approaches in EU farming systems to identify and facilitate more effective management strategies for European agriculture. This requires a wider systems perspective, considering socio-economic, ecological and political settings at a territorial level. We will operationalise a socio-ecological systems framework that integrates external settings into a sustainability assessment of farming systems, paying particular attention to the role of different types of actors and their roles in sub-systems. UNISECO will provide a methodological toolkit to assess the environmental, economic and social impacts of innovative strategies and incentives for agro-ecological approaches in EU farming systems at farm and territorial levels. The methodological toolkit will be tested in participatory case studies in 15 European countries with different biophysical, socio-economic and socio-cultural contexts of farming systems. UNISECO is committed to a genuine transdisciplinary process, reflected in consortium composition of stakeholder and scientific partners, and the emphasis on multi-actor engagement. Group learning processes, integrating practical and theoretical knowledge, will benefit scientists, stakeholders and end-users through improved understanding on how to strengthen sustainability of EU farming systems. UNISECO addresses the work programme topic SFS-29-2017 and contributes to Sustainable Food Security by identifying and supporting farming systems that enable the production of healthy food while preserving the environment and bringing added value to farm households and the different stakeholders of the value chain.;4924771;4924771;H2020-SFS-2017-2;/RIA;JOHANN HEINRICH VON THUENEN-INSTITUT, BUNDESFORSCHUNGSINSTITUT FUER LAENDLICHE RAEUME, WALD UND FISCHEREI;DE;"THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN;GESTION AMBIENTAL DE NAVARRA S.A;THE JAMES HUTTON INSTITUTE;ASOCIATIA WWF PROGRAMUL DUNARE CARPATI ROMANIA;LUONNONVARAKESKUS;SVERIGES LANTBRUKSUNIVERSITET;FORSCHUNGSINSTITUT FUR BIOLOGISCHEN LANDBAU STIFTUNG;BIOINSTITUT OPS;EUROPEAN LANDOWNERS ORGANIZATION;AGRICULTURAL UNIVERSITY OF ATHENS;GEONARDO ENVIRONMENTAL TECHNOLOGIES LTD;UNIVERSITAET FUER BODENKULTUR WIEN;BALTIJAS VIDES FORUMS;BALTIJOS APLINKOS FORUMAS VSI;USTAV ZEMEDELSKE EKONOMIKY A INFORMACI;CONSIGLIO PER LA RICERCA IN AGRICOLTURA E L'ANALISI DELL'ECONOMIA AGRARIA;INSTITUT SUPERIEUR D'AGRICULTURE RHONE ALPES I.S.A.R.A";"UK;ES;RO;FI;SE;CH;CZ;BE;EL;HU;AT;LV;LT;IT;FR";;0;1;0;0;0;1 210992;742573;MECSPEC;SIGNED;H2020-EU.1.1.;ERC-2016-ADG;H2020;Interaction and feedback between cell mechanics and fate specification in vertebrate gastrulation;2017-07-01;2022-06-30;;Embryogenesis is achieved by the close interplay between the gene regulatory networks that control cell fate specification and the physical processes by which the embryo takes shape. While each of these systems has been extensively investigated over the past decades, comparably little is yet known about how they functionally interact across different scales of organization within the physiological context of the developing embryo. The central aim of this proposal is to elucidate the fundamental principles underlying the interaction and feedback between cell mechanics and fate specification during vertebrate gastrulation. Using zebrafish as a vertebrate model organism, we will explore how germ layer progenitor cell fate specification affects the physical processes by which the gastrula takes shape, and, vice versa, how alterations in cell/tissue mechanics feed back onto the gene regulatory networks and signals controlling progenitor cell fate specification during gastrulation. To dissect the fundamental mechanisms underlying this crosstalk, we will combine genetic, cell biological and biophysical experimentation with mathematical modeling. We expect that this transdisciplinary approach will provide answers to a central yet unresolved question in developmental biology: how the interplay between cell mechanics, dynamics and fate specification drives embryo morphogenesis and patterning.;2306862;2306862;ERC-2016-ADG;/ERC-ADG;Institute of Science and Technology Austria;AT;;;;0;1;0;0;0;1 218321;823948;REMIND;SIGNED;H2020-EU.1.3.3.;MSCA-RISE-2018;H2020;Renewable Energies for Water Treatment and REuse in Mining Industries;2018-11-01;2022-10-31;;"The overall aim of REMIND is to develop an innovative framework of interplay between Renewable Energy Sources (RES) and innovative Water Treatment Technologies in the logic of a sustainable growth for mining industries. The novel paradigms explored are expected to drastically reduce the environmental impact due to extensive water and energy consumption, and to release of untreated wastewater during the production cycle of copper and gold. The REMIND collaborative network among European Union, Chile and Ecuador is in line with EU policy and strategy for raw materials supply; moreover, this partnership supports the economic and research efforts of Latin American countries towards a more eco-friendly and RES-driven development. The bi-directional knowledge transfer activities implemented in REMIND aim to: i) implement a rational use of water resources in the logic of circular economy; ii) promote a carbon-free technological approach (water-energy nexus) for reducing conventional energy resources requirements, and iii) mitigate health environmental risk in two demonstration sites (mining districts of Antofagasta – CL and Regione de l’Oro – EC), and iv) exploit the intersectorial cooperation between academia and industry by setting best practices for knowledge transfer in analogous contexts. REMIND brings together 8 leading High Education Institutions and Large Companies from 4 Countries (Italy, Spain, Chile and Ecuador), and implements a multisectorial and transdisciplinary network that generates 64 secondments and 73 Knowledge Transfer Activities.";1329400;1329400;H2020-MSCA-RISE-2018;/MSCA-RISE;UNIVERSITA DELLA CALABRIA;IT;"RINA CONSULTING SPA;POLITECNICO DI TORINO;UNIVERSIDAD DE SEVILLA";"IT;ES";;0;1;0;0;0;1 215454;796520;PEPPER;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Positive Environment in Public Participation and Engagement for Responsible Research and Innovation;2018-09-03;2020-09-02;;Public engagement is one of key components for responsible research and innovation that the European Commission has identified and promoted. However, it has been questioned about legitimating the process and result, contributing to policy decisions and facilitating social learning. It is now also challenged by the recent post-truth movement in terms of democracy, citizenship and sustainability. Positive experiences of active involvement within society can be critical to engage with the silent majority and marginalised majorities, as well as researchers under pressure of public engagement. This research thus examines positive environment in top-down, expert-led public engagement or bottom-up, grassroots activities such as citizen science and open innovation, in which responsibility is distributed to experts, stakeholders and citizens in a more natural and proportional manner. It identifies methodologies to incorporate voices and values of less engaged individuals and future generations into the design and implementation of positive engagement, developing novel approaches to visualise participants’ perceptions and perspectives and/or emerging technologies and their ethical, legal and social aspects. This transdisciplinary research collects and analyses data on individual, community and organisational and societal level through the study of selected cases of positive engagement, with reference to community-based participatory research, intergenerational ethics and organisation and management studies. Introducing a wide variety of Norwegian practices to the European research and policy context, the project will disseminate the research results to the case organisations and their affiliations and networks and finally produce a communication training manual for positive engagement. This fellowship also gives a good opportunity to exchange knowledge on public engagement practiced in Europe and Japan.;208400,4;208400,4;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;OSLOMET - STORBYUNIVERSITETET;NO;;;;0;1;0;0;0;1 220371;824711;MICS;SIGNED;H2020-EU.5.c.;SwafS-15-2018-2019;H2020;Developing metrics and instruments to evaluate citizen science impacts on the environment and society;2019-01-01;2021-12-31;;"THE MICS project brings together a transdisciplinary team to address a scientific and policy priority area where citizen science has the potential to promote a paradigm shift. Nature-based solutions (NBSs) are actions to protect, sustainably manage and restore natural or modified ecosystems that address societal challenges and provide human well-being. NBSs have increasingly become policy and planning objectives, but major knowledge gaps in NBSs science have hindered their implementation and acceptance. This is largely due to a lack of locally specific information about the influence of: climate, location, condition and management on NBS function and impact. Furthermore, the sustainability of NBSs often depends on the perceptions and needs of stakeholders, including user groups, local communities, conservation bodies, farmers, land managers, policy makers and practitioners. Due to their systemic complexity and embedding in local context, NBSs offer a unique potential for citizen science to make a major contribution. The MICS project will support NBS research by developing strategies and tools to evaluate impacts on science and society resulting from the integration of citizen science. These tools will foster citizen science approaches that increase both scientific knowledge, and how scientific evidence is taken up by communities and policy makers. MICS will use novel impact-assessment metrics and instruments that measure costs and benefits of citizen science in relation to the NBSs, with particular attention in the domains of society; democracy; the economy; NBS science, and citizen scientists. These instruments will be grounded in a comprehensive conceptual framework and integrated into an open platform following rigorous validation in key pilot sites along a West-East EU axis. This will test the applicability of the MICS impact-assessment tools in regions with differing opportunities and constraints for NBSs, and with different levels of citizen science uptake.";1944428;1944428;H2020-SwafS-2018-1;/RIA;CONSERVATION EDUCATION AND RESEARCH TRUST;UK;"THE RIVER RESTORATION CENTRE;STICHTING IHE DELFT INSTITUTE FOR WATER EDUCATION;INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU GEOLOGIE SI GEOECOLOGIE MARINA-GEOECOMAR;GEONARDO ENVIRONMENTAL TECHNOLOGIES LTD;AUTORITA' DI BACINO DISTRETTUALE DELLE ALPI ORIENTALI";"UK;NL;RO;HU;IT";;0;1;0;0;0;1 212039;724530;LIFEGATE;SIGNED;H2020-EU.1.1.;ERC-2016-COG;H2020;Holographic super-resolution micro-endoscopy for in-vivo applications;2017-11-01;2022-10-31;;"Complexity of living matter currently poses the most significant barrier to modern in-vivo microscopy. Fuelled by various branches of life sciences, the race is now to increase the penetration depth of super-resolution imaging inside living organisms. Additionally, no high-resolution in-vivo imaging technique has ever been introduced into medical, particularly surgical practice. This proposal sets out to develop new, ultra-thin endoscopic devices exceeding by orders of magnitude the performance of the current state of the art, thus paving the way for acquiring high-quality images from unprecedented depths of the most delicate tissues of living organisms. A team of transdisciplinary experts will push the fundamental and technological limits of the enabling principle - holographic control of light propagation in multimode fibres. Through advanced analytical and numerical modelling and major advancement of experimental methods, the project will develop a powerful platform for fast and efficient recovery of randomised imagery, retrieved from both rigid and flexible single-fibre endoscopes. This ‘gate-through-life’ will enable the team to deploy several prominent light-based imaging methods, including super-resolution approaches, inside freely moving animal models and ultimately humans. Supported by partners with broad expertise in in-vivo imaging, I will apply this methodology in the first instance to Neuroscience. This will provide a new, minimally invasive window into fundamental processes behind sub-cellular-scale functional connectivity of neurons and onset of common disabling neuronal disorders such as Alzheimer’s disease. Lastly, I will introduce the first technological basis for keyhole clinical diagnostics, enabling intra-operative live histology and microsurgery. This new imaging capacity will be able to reach currently inaccessible regions of the human body, while providing images with sub-cellular resolution in-situ.";1997973;1997973;ERC-2016-COG;/ERC-COG;LEIBNIZ-INSTITUT FUER PHOTONISCHE TECHNOLOGIEN E.V.;DE;UNIVERSITY OF DUNDEE;UK;;0;1;0;0;0;1 210165;727577;AgriLink;SIGNED;"H2020-EU.3.2.4.;H2020-EU.3.2.1.;H2020-EU.3.2.2.";RUR-14-2016;H2020;AgriLink. Agricultural Knowledge: Linking farmers, advisors and researchers to boost innovation.;2017-06-01;2021-05-31;;"AgriLink aims to stimulate sustainability transitions in European agriculture through better understanding the roles played by farm advice in farmer decision-making. To this end, AgriLink will analyse and improve the role of farmer advice in 8 innovation areas that combine challenges identified in the “Strategic Approach to EU Agricultural Research & Innovation”. AgriLink builds on the premise that the full range of advice-providing organisations need to be included in the assessment of service provision and innovation adoption. The methodology combines theoretical insights with cutting edge research methods within a multi-actor, transdisciplinary approach. It draws on ‘micro-AKIS’ (individuals and organisations from whom farmers seek services and exchange knowledge with) analysis in 26 focus regions, sociotechnical scenario development and ‘living laboratories’ where farmers, advisors and researchers work together. Research in focus regions will provide insight in farmers’ micro-AKIS, advisory suppliers’ business models, and regional farm advisory systems. This will feed an assessment of the efficacy of governance of farm-advice-research interactions across Europe. Newly developed advisory methods and new forms of research-practice interaction will be validated and further developed in Living Laboratories. A socio-technical scenario method will be used to explore, jointly with stakeholders, transition pathways towards more sustainable agriculture. Crucially, AgriLink builds on insights and experiences from both research and practice. The consortium consists of researchers from different disciplines (institutional economics, innovation studies, AKIS studies, sociology of networks), as well as of advisors (from public, private and farmer-based organisations) from across the EU. Actors from advisory services will be active in the validation and dissemination of results, to ensure that all project findings are both scientifically sound and practically useful.";4999966,49;4999966,49;H2020-RUR-2016-2;/RIA;INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE;FR;"EKOTOXA SRO;THE JAMES HUTTON INSTITUTE;UNIVERSIDADE DE TRAS-OS-MONTES E ALTO DOURO;VINIDEA SRL;INRA TRANSFERT S.A.;CENTRUM DORADZTWA ROLNICZEGO W BRWINOWIE;INSTITUTO NAVARRO DE TECNOLOGIAS E INFRAESTRUCTURAS AGROALIMENTARIAS SA;STIFTELSEN RURALIS INSTITUTT FOR RURAL- OG REGIONALFORSKNING;BOERENBONDVERENIGING VOOR INNOVATIEVE PROJECTEN VZW;NODIBINAJUMS BALTIC STUDIES CENTRE;AGRICULTURAL UNIVERSITY OF ATHENS;HIGHCLERE CONSULTING SRL;USTAV ZEMEDELSKE EKONOMIKY A INFORMACI;THE OPEN UNIVERSITY;STICHTING WAGENINGEN RESEARCH";"CZ;UK;PT;IT;FR;PL;ES;NO;BE;LV;EL;RO;NL";;0;1;0;0;0;1 216509;787258;InclusivePublicSpace;SIGNED;H2020-EU.1.1.;ERC-2017-ADG;H2020;Inclusive Public Space: Law, Universality and Difference in the Accessibility of Streets;2019-01-01;2023-12-31;;"This project considers the accessibility of public space – focusing on pedestrian access to streets. It explores law’s engagement with the exclusion which occurs when streets are designed, operated or managed so as to deny access to pedestrians whose bodies, minds or life circumstances do not ‘fit’. Such exclusion is damaging both to individuals and communities. With a view to understanding how states and the EU can more effectively ensure that public space is inclusive, the project aims to deepen understanding of what physical features of streets are experienced as exclusionary in 5 countries and by whom; how effectively law is used to challenge such exclusion in these countries; and how the problem is perceived and politically challenged. It also aims to foster shared concern about this form of exclusion, in the 5 countries and beyond, and to raise awareness of how law can be used to challenge it. The methodology will be comparative, transdisciplinary and participatory in nature. It will develop innovative videovoice techniques for data gathering. It will also develop groundbreaking awareness-raising tools – such as software to simulate experiences of pedestrian exclusion – as well as digital story telling and legal orientation guides. Theoretical context and framing will be provided by an innovative blending of Martha Fineman’s universal vulnerability thesis with the social model of disability. The project will be the first to bring a multinational sociolegal perspective to bear on this significant social justice problem. It is timely - given concerns about the move in EU countries (often supported by EU funding) toward streets in which space is shared by vehicles and pedestrians; and the ratification (including by the EU) of the UN Convention on the Rights of Persons with Disabilities, which is the first such treaty to include provisions on the accessibility of public space.";2499672;2499672;ERC-2017-ADG;/ERC-ADG;UNIVERSITY OF LEEDS;UK;;;;0;1;0;0;0;1 220129;814530;NANORIGO;SIGNED;"H2020-EU.2.1.3.;H2020-EU.2.1.2.";NMBP-13-2018;H2020;Establishing a Nanotechnology Risk Governance Framework;2019-01-01;2023-02-28;;The main objective of NANORIGO (NANOtechnology RIsk GOvernance) is to develop and implement a transparent, transdisciplinary and science-based Risk Governance Framework (RGF) for managing nanotechnology risks regarding social, environmental and economic benefits. A new risk management approach is formed based on available and new high-quality data and advanced scientific tools developed for industry and regulators decision-making, and on communication with all stakeholders (regulators, industries, politicians, the civil society). The RGF will use a life-cycle perspective and integrate available knowledge on ethical, social, environmental and economic concerns into a user-friendly format that can be easily adapted and transferred into regulation for hazard, exposure and risk assessment and management of nanomaterials. It will consist of: (i) risk management strategies based on reinforced tools for guidance and decision-making developed for risk assessment, (ii) validated methodologies to identify potential hazard and exposure, and (iii) a web-based information and communication platform to facilitate access to good quality data and a clear understanding of risks for all stakeholders, and their valuable feedback. The NANORIGO work plan consists of 8 work packages covering all major risk governance aspects. A self-sustained European Nanotechnology Risk Governance Council (NRGC) will be installed to implement the RGF, embedded in relevant international structures and in close cooperation with the International Risk Governance Center (IRGC). Case studies will demonstrate the sustainability of solutions and their consistent integration into regulatory applications under real conditions. Bringing all stakeholders together under a common umbrella will allow to share and integrate the most appropriate governance tools, frameworks and plans for future science and regulatory research and foster consistency of management approaches in the EU and synergies internationally.;4748740;4748740;H2020-NMBP-TO-IND-2018;/RIA;AARHUS UNIVERSITET;DK;"INSTITUTO TECNOLOGICO DEL EMBALAJE, TRANSPORTE Y LOGISTICA;REUTHER RUDOLF;DECHEMA GESELLSCHAFT FUER CHEMISCHE TECHNIK UND BIOTECHNOLOGIE E.V.;TRANSGERO LIMITED;SOCIEDADE PORTUGUESA DE INOVACAO - CONSULTADORIA EMPRESARIAL E FOMENTO DA INOVACAO S.A.;NATIONAL TECHNICAL UNIVERSITY OF ATHENS - NTUA;FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.;HELMHOLTZ-ZENTRUM FUR UMWELTFORSCHUNG GMBH - UFZ;PARIS-LODRON-UNIVERSITAT SALZBURG;ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE;FUNDACION GAIKER;GRUPO ANTOLIN-INGENIERIA SA;UNIVERSITAET BREMEN;Quercus - Associaç?o nacional de Conservaç?o da natureza;UNIVERSIDADE DE AVEIRO;OPTIMAT LIMITED;BUNDESANSTALT FUER MATERIALFORSCHUNG UND -PRUEFUNG;ETSS AG;UNIVERSITAET FUER BODENKULTUR WIEN;WOMEN ENGAGE FOR A COMMON FUTURE FRANCE (WECF);EUROPEAN ENVIRONMENTAL CITIZENS ORGANISATION FOR STANDARDISATION;SCHUURBIERS DANIEL;ONDERZOEK EN ADVIESGROEP QUESTIONSANSWERS AND MORE BV;EIDGENOSSISCHE MATERIALPRUFUNGS- UND FORSCHUNGSANSTALT;OEKO-INSTITUT E.V. - INSTITUT FUER ANGEWANDTE OEKOLOGIE;TYOTERVEYSLAITOS;UNIVERZA V LJUBLJANI;JRC -JOINT RESEARCH CENTRE- EUROPEAN COMMISSION";"ES;DE;IE;PT;EL;AT;CH;UK;FR;BE;NL;FI;SI";;0;1;0;0;0;1 218086;802582;DissectingSociety;SIGNED;H2020-EU.1.1.;ERC-2018-STG;H2020;Nineteenth-Century Sociographic Journalism and the Formation of Ethnographic and Sociological Knowledge;2019-11-01;2024-10-31;;"This project enacts cutting-edge perspectives on the multigenre history of sociological and anthropological reasoning. It represents the first comprehensive study to investigate pieces of nineteenth-century sociographic journalism as formative frames/catalysts of social knowledge and science. These social sketches (often referred to as panoramic literature) provide rich ethnographic micro-analysis and often relate to debates held by statisticians, moralists, folklorists, and ethnologists. However, in the discipline-oriented histories of the social sciences and humanities, journalism has been ignored as a form of knowledge and as a founding genre of modern (disciplinary, academic) social science. By exploring the epistemic significance of sociographic journalism, the project promises to institute a cross-genre, transdisciplinary, and transnational historiography of the evolution of social knowledge and to revise mono-disciplinary and Eurocentric tales of the past and present. The project has five kinds of outcome: a series of essays, a conference, a public exhibition, a volume, and two monographs. The corpus comprises social sketches and examples of related knowledge frames (travel accounts, philanthropic reports, caricatures etc.) from Western Europe, the German-speaking countries, and (post-)colonial Latin America. The project develops an innovative mix of anthropological/historiographical approaches to examine (1) the representational techniques of sociographic journalism (e.g., methods of constructing social types, the influence of scientific paradigms); (2) how it connects with epistemic developments (e.g., towards materialist and historicizing conceptions of society); (3) its embeddedness in socio-spatial settings and its relations to academic, artistic, and governmental projects; and (4) how the journalistic sketches are to be situated against processes of urbanization, cultural transfer, nation-building, and the institutionalization of academic disciplines.";1477125;1477125;ERC-2018-STG;/ERC-STG;LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN;DE;;;;0;1;0;0;0;1 216321;801126;EDIT;SIGNED;H2020-EU.1.2.1.;FETOPEN-01-2016-2017;H2020;Novel precision technological platforms to promote non-invasive early diagnosis, eradicationand prevention of cancer relapse: proof of concept in the bladder carcinoma.;2018-10-01;2022-09-30;;"Unmet clinical needs in the management of bladder cancer (BCa) are the prevention of tumor onset, relapse and progression, and therapy of the aggressive carcinoma in situ (Cis), requiring weekly treatments and endless follow-up, with a consequent poor quality of life and the highest cost per patient among all cancers. Therefore, public health programs crave for early BCa detection protocols, to improve performance in the management of this devastating disease. Here we propose an advanced transformative technology termed EDIT combining a novel high-resolution ultrasound elastography and photoacoustic imaging on the bladder instilled with targeted plasmonic gold sensors. EDIT approach exploits the structural and mechanical properties of the bladder extracellular matrix (ECM) as a unique biomarker of the early onset/progression/relapse of carcinoma, through engineered novel gold nanorods (GNRs) used as intravesical photoacoustic antennas targeted at the ECM, generating an ad hoc visualization platform. GNRs will be further utilized as heat-releasing effectors at nanoscale for targeted cancer photo-thermal therapy. EDIT is designed to detect pre-neoplastic area and eradication of local areas at few cells resolution with high sensitivity and specificity. We bring together a multi and transdisciplinary consortium capable to develop non-invasive and non-ionizing novel technology and preclinical validation for early prognosis of BCa and therapeutic nanomedicine against bladder Cis. Outcomes of EDIT will revolutionize the management of BCa with the introduction of sensing and effector nanotechnologies combined with non-invasive organ imaging with high resolution/definition by 3D ultrasound and photoacoustic imaging. Structural and mechanical modification of the ECM is a common denominator for invasive breast, colorectal, prostate and bladder cancers. EDIT platforms will also pave the ways for the earlier management of other bladder-related pathologies and solid tumors.";4317160;4317160;H2020-FETOPEN-1-2016-2017;/RIA;OSPEDALE SAN RAFFAELE SRL;IT;"LIME TECHNOLOGY IKE;WEIZMANN INSTITUTE OF SCIENCE;ASCEND TECHNOLOGIES LIMITED;OSM-DAN LTD;CONSIGLIO NAZIONALE DELLE RICERCHE;UNIVERSITA DEGLI STUDI DI MILANO;ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA;FUJIFILM SONOSITE BV";"EL;IL;UK;IT;NL";;0;1;0;0;0;1 214917;788317;SySTEM 2020;SIGNED;H2020-EU.5.d.;SwafS-11-2017;H2020;SySTEM 2020: Connecting Science Learning Outside The Classroom;2018-05-01;2021-04-30;;SySTEM 2020 will focus on science learning outside the classroom, mapping the field across Europe, evaluating a number of transdisciplinary programmes to design best principles for educators in this field, and also examining individual learning ecologies by piloting self-evaluation tools for learners which will document science learning outside of the classroom. This study will map practices in 19 EU countries, including in-depth studies in 8 of these countries, covering learners between 9 - 20 years from various backgrounds including those from geographically remote, socio-economically disadvantaged, minority and/or migrant communities.;2999982;2999982;H2020-SwafS-2017-1;/RIA;THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN;IE;"UNTERNEHMENSGRUPPE DER STADT LINZ HOLDING GMBH;AALTO KORKEAKOULUSAATIO SR;CENTAR ZA PROMOCIJU NAUKE;COC OFFICE AS;ZENTRUM FUR SOZIALE INNOVATION GMBH;ZAVOD ZA KULTURO, UMETNOST IN IZOBRAZEVANJE KERSNIKOVA;ASSOCIATION EUROPEENNE DES EXPOSITIONS SCIENTIFIQUES TECHNIQUES ET INDUSTRIELLES;STICHTING WAAG SOCIETY;FONDAZIONE MUSEO NAZIONALE DELLA SCIENZA E DELLA TECNOLOGIA LEONARDO DA VINCI;LATRA EE";"AT;FI;RS;DK;SI;BE;NL;IT;EL";;0;1;0;0;0;1 216577;787516;GLOBEGOV;SIGNED;H2020-EU.1.1.;ERC-2017-ADG;H2020;The Rise of Global Environmental Governance:A History of the Contemporary Human-Earth Relationship;2018-10-01;2023-09-30;;"GLOBEGOVE is a historical study of humanity’s relation to planetary conditions and constraints and how it has become understood as a governance issue. The key argument is that Global Environmental Governance (GEG), which has arisen in response to this issue, is inseparable from the rise of a planetary Earth systems science and a knowledge-informed understanding of global change that has affected broad communities of practice. The overarching objective is to provide a fundamentally new perspective on GEG that challenges both previous linear, progressivist narratives through incremental institutional work and the way contemporary history is written and understood. GLOBEGOVE will be implemented as an expressly global history along four Trajectories, which will ensure both transnational as well as transdisciplinary analysis of GEG as a major contemporary phenomenon. Trajectory I: Formation articulates a proto-history of GEG after 1945 when the concept of ‘the environment’ in its new integrative meaning was established and a slow formation of policy ideas and institutions could start. Trajectory II: The complicated turning of environmental research into governance investigates the relation between environmental science and environmental governance which GLOBEGOV examines as an open ended historical process. Why was it that high politics and diplomacy came in closer relations with environmental sciences? Trajectory III: Alternative agencies – governance through business and civic society explores corporate responses, including self-regulation through the concept of Corporate Social Responsibility, to growing concerns about environmental degradation and pollution, and business-science relations. Trajectory IV: Integrating Earth into History – scaling, mediating, remembering will turn to historiography itself and examine how concepts and ideas from the rising Earth system sciences have been influencing both GEG and the way we think historically about Earth and humanity.";2568125;2500000;ERC-2017-ADG;/ERC-ADG;KUNGLIGA TEKNISKA HOEGSKOLAN;SE;;;;0;1;0;0;0;1 196013;660953;Lx Micelles;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Coordination chemistry in doubly stabilized micelles for the tageted delivery of cytostatic drugs in cancer therapy;2015-06-01;2017-05-31;;"The treatment of cancer with chemotherapeutic drugs is very often associated with severe side effects limiting their tolerated dose and leading to insufficient therapeutic effects. The application of such drugs in nanometer-sized micelles may improve their biodistribution, but in vivo studies showed fast drug release in the blood stream. We aim for prolonged drug retention and intracellular release by introducing the stable, yet reversible Lx linker in the core of bioresorbable polymeric micelles. This coordinative platinum linker will have two functions: (1) it will facilitate the stable conjugation between the drug molecule and the polymer molecules constituting the micelle and (2) it will act as a stabilizer between the polymer molecules constituting the micelle. This will result in excellent stability of the drug-loaded micelles in circulation. Due to the enhanced permeability and retention effect the micelles will accumulate in tumor tissue, where they will be destabilized intracellularly and the drugs will be released from the linker in the cytoplasm after competitive glutathione displacement. The Lx linker presents various advantages over other crosslink methods, such as versatility and ease of crosslinking. No platinum-related toxicity was observed in vivo for the linker in previous research. In addition, the amount of platinum may be considered negligible since powerful drugs will be loaded onto the micelles. This approach represents a safe and unique hybrid method which has the potential to significantly increase the amount of drug deposited at the target tissue and to reduce side effects at non-target sites. By pursuing this significant step forward in cancer therapy, the fellowship will broaden the Experienced Researcher’s scientific and non-scientific skills via advanced training as well as transnational and transdisciplinary mobility. Furthermore, it will facilitate a lively transfer of knowledge between the participants due to their complementarity.";173076;173076;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FR;;;;0;1;0;0;0;1 215945;770747;LIFT;SIGNED;H2020-EU.3.2.1.1.;SFS-29-2017;H2020;Low-Input Farming and Territories - Integrating knowledge for improving ecosystem-based farming;2018-05-01;2022-04-30;;"Ecological approaches to farming practices are gaining interest across Europe. As this interest grows there is a pressing need to assess the potential contributions these practices may make, the contexts in which they function and their attractiveness to farmers as potential adopters. In particular, ecological agriculture must be assessed against the aim of promoting the improved performance and sustainability of farms, rural environment, rural societies and economies, together. The overall goal of LIFT is to identify the potentiel benefits of the adoption of ecological farming in the European Union (EU) and to understand how socio-economic and policy factors impact the adoption, performance and sustainability of ecological farming at various scales, from the level of the single farm to that of a territory. To meet this goal, LIFT will assess the determinants of adoption of ecological approaches, and evaluate the performance and overall sustainability of these approaches in comparison to more conventional agriculture across a range of farm systems and geographic scales. LIFT will also develop new private arrangements and policy instruments that could improve the adoption and subsequent performance and sustainability of the rural nexus. For this, LIFT will suggest an innovative framework for multi-scale sustainability assessment aimed at identifying critical paths toward the adoption of ecological approaches to enhance public goods and ecosystem services delivery. This will be achieved through the integration of transdisciplinary scientific knowledge and stakeholder expertise to co-develop innovative decision-support tools. The project will inform and support EU priorities relating to agriculture and the environment in order to promote the performance and sustainability of the combined rural system. At least 30 case studies will be performed in order to reflect the enormous variety in the socio-economic and bio-physical conditions for agriculture across the EU.";5000000;5000000;H2020-SFS-2017-2;/RIA;INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE;FR;"ELLINIKOS GEORGIKOS ORGANISMOS - DIMITRA;INSTITUT D ENSEIGNEMENT SUPERIEUR ET DE RECHERCHE EN ALIMENTATION SANTE ANIMALE SCIENCES AGRONOMIQUES ETDE L ENVIRONNEMENT VETAGRO SUP;INRA TRANSFERT S.A.;SRUC;INSTYTUT ROZWOJU WSI I ROLNICTWA POLSKIEJ AKADEMII NAUK;SVERIGES LANTBRUKSUNIVERSITET;TEAGASC - AGRICULTURE AND FOOD DEVELOPMENT AUTHORITY;RHEINISCHE FRIEDRICH-WILHELMS-UNIVERSITAT BONN;INSTITUTE OF AGRICULTURAL ECONOMICS;UNIVERSITY OF KENT;UNIVERSITAET FUER BODENKULTUR WIEN;ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA;MAGYAR TUDOMANYOS AKADEMIA KOZGAZDASAG- ES REGIONALIS TUDOMANYI KUTATOKOZPONT;ECOZEPT GBR;KATHOLIEKE UNIVERSITEIT LEUVEN;JRC -JOINT RESEARCH CENTRE- EUROPEAN COMMISSION";"EL;FR;UK;PL;SE;IE;DE;RO;AT;IT;HU;BE";;0;1;0;0;0;1 216474;773330;GAIN;SIGNED;H2020-EU.3.2.3.;SFS-32-2017;H2020;Green Aquaculture Intensification in Europe;2018-05-01;2021-10-31;;"GAIN is designed to support the ecological intensification of aquaculture in the European Union (EU) and the European Economic Area (EEA), with the dual objectives of increasing production and competitiveness of the industry, while ensuring sustainability and compliance with EU regulations on food safety and environment. Eco-intensification of European aquaculture is a transdisciplinary challenge that requires the integration of scientific and technical innovations, new policies and economic instruments, as well as the mitigation of social constraints. Successful eco-intensification of aquaculture will provide more and better aquatic products, more jobs, and improve trade balance by reducing imports. GAIN, besides looking at innovative ways of integrating cultured species, will seek integration with other sectors, in order to promote the implementation of the principles of circular economy in Aquaculture. The GAIN Consortium includes a wide range of complementary expertise and a well blended mix of research institutes and industrial partners, which will ensure the achievement of the following specific objectives: (i) Develop and optimize sustainable feeds, without increasing the pressure on land and fish stocks; (ii) Add value to cultivation, by means of innovative processes, which turn both by-products and side-streams into valuable secondary materials, thus increasing profits and minimizing the environmental footprint; (ii) Improve the management of finfish and shellfish farms, in terms of FCR, fish welfare and reduction of wastes, through the use of sensors, biomarkers, Big Data, IoT (Internet of Things) and predictive mathematical models; (iv) Support integrated policies and address current barriers to the implementation of the principles of circular economy in aquatic production.";6109648,75;5998795;H2020-SFS-2017-2;/RIA;UNIVERSITA CA' FOSCARI VENEZIA;IT;"GILDESKAL FORSKNINGSSTASJON AS;DALHOUSIE UNIVERSITY;MULTIVECTOR AS;ASOCIACION NACIONAL DE FABRICANTES DE CONSERVAS DE PESCADOS Y MARISCOS-CENTRO TECNICO NACIONAL DE CONSERVACION DE PRODUCTOS DE LA PESCA;IBM IRELAND LIMITED;AGRIFOOD AND BIOSCIENCES INSTITUTE;AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS;JOHANN HEINRICH VON THUENEN-INSTITUT, BUNDESFORSCHUNGSINSTITUT FUER LAENDLICHE RAEUME, WALD UND FISCHEREI;ALFRED-WEGENER-INSTITUT HELMHOLTZ-ZENTRUM FUR POLAR- UND MEERESFORSCHUNG;Sagremarisco-Viveiros de Marisco Lda;LEBECHE SPAIN SL;THE UNIVERSITY OF STIRLING;SPAROS LDA;FONDAZIONE EDMUND MACH;LONGLINE ENVIRONMENT LIMITED;WAGENINGEN UNIVERSITY;SALTEN HAVBRUKSPARK AS;SOUTH CHINA SEA FISHERIES RESEARCH INSTITUTE, CHINESE ACADEMY OF FISHERIES SCIENCES;ZACHODNIOPOMORSKI UNIWERSYTET TECHNOLOGICZNY W SZCZECINIE";"NO;CA;ES;IE;UK;DE;PT;IT;NL;CN;PL";;0;1;0;0;0;1 197445;665759;EnRRICH;SIGNED;H2020-EU.5.a.;SEAC-2-2014;H2020;Enhancing Responsible Research and Innovation through Curricula in Higher Education (EnRRICH);2015-07-01;2018-03-31;;"The Enhancing Responsible Research and Innovation through Curricula in Higher Education (EnRRICH) project will build the capacity of staff in higher education to facilitate their students’ development of knowledge, skills and attitudes and competencies in responsible research and innovation, and respond to the research needs of society, particularly underserved civil society organisations (CSOs). It will do this by identifying, developing, testing, and disseminating resources, based on existing good practice and trials of new initiatives, to embed the five RRI keys in academic curricula across Europe, with specific reference to science and engineering. It will develop case studies which showcase examples for students, teachers, professional trainers and academic staff of HEIs. Through ongoing dialogue with academics, policymakers, and CSOs, EnRRICH will kick start debates at institutional, national and international levels to create awareness of, and enhance the policy context for, RRI in curricula and thereby produce more responsible and responsive graduates and researchers. These objectives will be achieved building on the Public Engagement with Research and Research Engagement with Society (PERARES) and RRI Tools projects. It will involve new partners as well as a core of established partners drawn from HEIs and CSOs, including from RRI tools. It will establish an advisory board drawn from relevant organisations to ensure the widest possible engagement and dissemination. Work packages will deal with project management, state of the art of good practices in introducing RRI into curriculum development, exchange and trialling of good practices at national, international and transdisciplinary levels, policy development, evaluation, dissemination and a conference. Deliverables will include case studies and policy papers, and materials and resources for academic staff to involve students in experiential learning about RRI, including projects in partnership with CSOs";1499396,63;1499396,63;H2020-SEAC-2014-1;/CSA;VRIJE UNIVERSITEIT BRUSSEL;BE;"COMUNAUTE D'UNIVERSITES ET ETABLISSEMENTS UNIVERSITE DE LYON;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;BUDAPESTI CORVINUS EGYETEM;INSTITIUID TEICNEOLAIOCHTA BHAILE ATHA CLIATH;FUNDACIO PRIVADA INSTITUT DE RECERCA DE LA SIDA-CAIXA;UNIVERSITAET VECHTA;THE QUEEN'S UNIVERSITY OF BELFAST;UNIVERSITA DEGLI STUDI DI SASSARI;VILNIAUS TECHNOLOGIJU IR DIZAINO KOLEGIJA;WAGENINGEN UNIVERSITY;WISSENSCHAFTSLADEN BONN EV;UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK";"FR;UK;HU;IE;ES;DE;IT;LT;NL";;0;1;0;0;0;1 216371;810961;CUDAN;SIGNED;H2020-EU.4.c.;WIDESPREAD-03-2017;H2020;Cultural Data Analytics;2019-01-01;2023-12-31;;The broad framework of the recent EU Digital Single Market strategy has prepared the ground for many of the guidelines and future directions in cultural heritage digitisation and in the area of open data policies. In line with this new strategy, the core document for Estonian cultural policy, The General Principles of Cultural Policy up to 2020, sets out that most Estonian cultural heritage will be digitised by 2020 and the interoperability of culture-related information systems will be ensured by harmonised descriptions and web services. In connection with that, the 2020 Digital Agenda for Estonia emphasises that the public sector’s capacity to apply data analytics solutions needs to be increased significantly over the coming years and that Estonian cultural heritage should be digitally accessible and spreading through re-use. In accordance with these strategies, the CUDAN project aims to harness the existing strengths of Tallinn University in order to build a new analytical approach, called “Cultural Data Analytics”, that integrates cultural semiotics, data analytics, digital culture studies and creative industries’ studies to work with digitised cultural heritage as well as with born-digital data scraped from contemporary platforms. This aim will be accomplished by establishing the ERA Chair position and the transdisciplinary and innovative cooperation platform (Open Lab) at Tallinn University. Open Lab will cooperate with multiple external partners, both public and private, in order to collect, analyse and use digital cultural data and to develop relevant new analytic methods – all in order to better understand contemporary cultural dynamics and incorporate this understanding into public cultural service designs, and cultural and creative industries’ policymaking processes. The benefits will be that these designs and processes will become more evidence-based, agile and responsive to contemporary challenges.;2500000;2500000;H2020-WIDESPREAD-03-2017-ERAChairs;/CSA;TALLINN UNIVERSITY;EE;;;;0;1;0;0;0;1 212394;772835;NEWBIE;SIGNED;"H2020-EU.3.2.4.;H2020-EU.3.2.1.;H2020-EU.3.2.2.";RUR-10-2016-2017;H2020;New Entrant netWork: Business models for Innovation, entrepreneurship and resilience inEuropean agriculture;2018-01-01;2021-12-31;;Sustaining a cohort of new entrants is crucial to the ongoing vitality, resilience and competitiveness of the agricultural sector and rural regions in Europe. New entrants bring with them innovation and entrepreneurialism, as well as practical skills and networks developed on farms and through off-farm employment. However, new entrants face considerable challenges in entering the sector, particularly access to land, capital, labour and markets, but also business skills and knowledge development on both applied and theoretical levels. Analysis of Eurostat figures suggests that there is not an adequate replacement rate of young farmers in many European countries, although there is evidence of considerable innovation and comparatively high rates of new entrants in others (Zagata and Sutherland, 2015). The NEWBIE Network (New Entrant netWork: Business models for Innovation, entrepreneurship and resilience in European agriculture) has been designed to address the significant challenge of enabling new entrants to successfully establish sustainable farm businesses in Europe. The NEWBIE network will facilitate the development and dissemination of new business models, including new entry models, to the full range of new entrants - from successors to complete newcomers to the agricultural sector. This will be achieved by a transdisciplinary network of farming organisations, educators, advisors, researchers and industry stakeholders, who will assemble, assess and exchange the state of the art on new entrant farming enterprises, and establish national and European new entrant support networks. NEWBIE will focus particularly on enabling innovative business models developed by new entrants to be integrated into academic research and educational curricula, and broadly disseminated to new entrants across Europe.;1995040,75;1995040,75;H2020-RUR-2017-1;/CSA;STICHTING WAGENINGEN RESEARCH;NL;"THE JAMES HUTTON INSTITUTE;BUND DER DEUTSCHEN LANDJUGEND E.V. (BDL);RENETA (RESEAU NATIONAL DES ESPACES-TEST AGRICOLES);UNIVERSIDADE DE EVORA;SDRUJENIE-BISNES INKUBATOR-GOTSE DELCHEV, TSENTAR ZA PODPOMAGANE NA PREDPRIEMACHESTVOTO;FACHHOCHSCHULE SUDWESTFALEN;KATHOLIEKE UNIVERSITEIT LEUVEN;TEAGASC - AGRICULTURE AND FOOD DEVELOPMENT AUTHORITY;UNIVERZA V LJUBLJANI";"UK;DE;FR;PT;BG;BE;IE;SI";;0;1;0;0;0;1 204970;713726;MUTX;SIGNED;H2020-EU.1.1.;ERC-PoC-2015;H2020;MUTATION++ library, technology transfer from atmospheric entry plasmas to biomass pyrolysis;2016-08-01;2018-01-31;;One successful outcome of the AEROSPACEPHYS ERC StG, entitled “Multiphysics models and simulations for reacting and plasma flows applied to the space exploration program,” is the development of a new software library called MUTATION\\: MUlticomponent Thermodynamic And Transport properties for IONized gases in C\\. The library compiles the state-of-the-art physico-chemical models and algorithms developed by the team into a highly extensible and robust software package to be coupled to simulation tools used by space agencies and industries. The design of the library allows for high-performance integration in material and flow field simulation tools. MUTATION\\ is also shipped with several stand-alone tools that provide up-to-date basic data without proper software linking. Such a compromise allows simulation tool users, who do not have access to the source code, to benefit from these models. Taking community development to the next level requires the improvement and enrichment of the software testing framework and database, giving new users development guidelines and technology transfer examples. The MUTX project will allow us to extend the user base of MUTATION\\ to the corporate community. This will require the implementation of tests to ensure the preservation of the library functionalities and performance after each new release and on multiple hardware and software platforms. It will also require the addition of databases for real thermal protection materials currently being developed by the space industry in collaboration with the European Space Agency. The demonstration of a transdisciplinary technology transfer will be achieved by implementing a database for biomass pyrolysis simulation. One long-term goal of the MUTX project is to enable the PI and his team to obtain additional funding through participation in research contracts in collaboration with industrial partners using MUTATION\\.;149921;149921;ERC-2015-PoC;/ERC-POC;INSTITUT VON KARMAN DE DYNAMIQUE DES FLUIDES;BE;;;;0;1;0;0;0;1 216213;788231;ProgrES;SIGNED;H2020-EU.1.1.;ERC-2017-ADG;H2020;Programmable Enzymatic Synthesis of Bioactive Compounds;2018-07-01;2023-06-30;;Enzymes are now established as highly selective biocatalysts in organic synthesis with the range of catalysts and reactions rapidly increasing through access to large protein databases and high-throughput molecular biology tools for biocatalyst engineering. The diversity of biocatalytic reactions is now at a stage where they can be linked in (chemo)-enzymatic reaction cascades, where two or more chemical and/or enzymatic reactions can be catalysed simultaneously generating de novo biosynthetic pathways for chemical synthesis not found in Nature. These reaction cascades have demonstrated important prior art, however they have been mostly limited to few steps and lack the complexity provided by the natural pharmacopeia. ProgrES aims to achieve a step-change by introducing unprecedented structural complexity into de novo pathways and by moving away from manual to automated, high-throughput cascade design and implementation. The proposal is to use a transdisciplinary approach that addresses three important bottlenecks: i. Identification of enzymatic reactions that allow early functionalisation and late stage diversification of the cascade toolkit to increase structural complexity, building on C-H activation mediated by monooxygenases, which are well established in our research group. ii. As diversity of targets increases, high resolution structural analysis of pathway intermediates and products becomes a bottleneck, which is addressed by high-throughput label free mass spectrometry based analytical tools that will match the demands on timescale and numbers. iii. In parallel, we will establish bioinformatics tools adapted from both chemical synthesis and biosynthesis, to allow programmable enzymatic synthesis for cascade design. As proof-of-concept and test bed for the ProgrES platform we aim to generate a library of diverse synthetic imino sugars. This proposal will lead to a major breakthrough in creating a diverse range of scaffolds of therapeutic interest.;2399831;2399830;ERC-2017-ADG;/ERC-ADG;THE UNIVERSITY OF MANCHESTER;UK;;;;0;1;0;0;0;1 215940;773903;SHui;SIGNED;"H2020-EU.3.2.1.1.;H2020-EU.3.2.1.2.";SFS-47-2017;H2020;Soil Hydrology research platform underpinning innovation to manage water scarcity in European and Chinese cropping systems;2018-09-01;2022-08-31;;SHui is conceived as a network integrating long-term experiments of its 19 academic and SME partners across different environmental conditions and cropping systems in the EU and China. It provides a platform for research on soil-water resources management under water scarce conditions, to better understand the linkages between agricultural soil hydrology and sustainability and for a systematic assessment of adaptation and mitigation methods. It will develop and implement new strategies to increase water use efficiency and yield, based on sustainable intensification through integrated use of soil and water across different spatial scales. At farm level, this includes digital agriculture solutions integrating in situ and remote sensors and simulation models to exploit an improved understanding of the relationship between crop yield variability and soil hydraulic properties, optimizing circular approaches to re-use water and using waste water sources. These technical approaches are reliant on optimum data utilization and transdisciplinary research with multiple stakeholders. At regional scales, the aggregation of biophysical and socioeconomic variables in dynamic models will evaluate the impact of different policy strategies, to support decision makers to evaluate different scenarios of land-use dynamics, economic context and current and future climate in EU and China, including assessments of water and carbon footprint. SHui will exploit scientific, technological and social innovations by disseminating and communicating these to multiple stakeholders, and implementing novel technological packages from farm to large regional scales. It aims to make a significant contribution to the EU and China Research Agenda for Agriculture in providing food security and optimum use of scarce soil and water resources. Training a cohort of early career scientists in soil conservation and water-saving practices, SHui’s legacy will extend beyond the project duration.;5562745;4884493,75;H2020-SFS-2017-2;/RIA;AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS;ES;"FONDAZIONE PER LO SVILUPPO SOSTENIBILE DEL MEDITERRANEO;THE AGRICULTURAL RESEARCH ORGANISATION OF ISRAEL - THE VOLCANI CENTRE;GEORG-AUGUST-UNIVERSITAT GOTTINGENSTIFTUNG OFFENTLICHEN RECHTS;NORTHWEST A&F UNIVERSITY;BEIJING FORESTRY UNIVERSITY;CHANGJIANG RIVER SCIENTIFIC RESEARCH INSTITUTE;UNIVERSIDAD DE CORDOBA;NANJING AGRICULTURAL UNIVERSITY;HONG KONG BAPTIST UNIVERSITY;CESKE VYSOKE UCENI TECHNICKE V PRAZE;BEIJING NORMAL UNIVERSITY;TERRA NOVA PERIVALLONTIKI - TECHNIKI - SYMVOYLEYTIKI ETAIREIA PERIORISMENIS EYTHINIS;LANCASTER UNIVERSITY;UNIVERSITAET FUER BODENKULTUR WIEN;TERRAVISION LAB LTD;FUJIAN AGRICULTURE AND FORESTRY UNIVERSITY;KATHOLIEKE UNIVERSITEIT LEUVEN;CHINA AGRICULTURAL UNIVERSITY";"IT;IL;DE;CN;ES;HK;CZ;EL;UK;AT;BE";;0;1;0;0;0;1 214099;792178;SIZE;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;The role of size in the sustainability of irrigation systems;2019-09-01;2022-08-31;;Irrigated areas contribute c. 40% of the worldwide crop production and consume c. 70% of all freshwater resources. Knowing how to meet the food demands of an ever-growing population without compromising environmental integrity is thus a pressing issue of global concern. Following the line of evidence gathered for organisms, financial corporations and cities, size (e.g. the area, the dimensions) seems to be a master variable conditioning the behavior of irrigation systems as well. However, our knowledge on how size conditions irrigated systems is comparatively fragmentary and lacks in formalization due to overreliance in case studies. This sets our capacity to ensure their sustainability in very fragile ground. My project will break through this limitation by combining allometry, the study of global irrigation datasets and the collection of field data in irrigation systems of Spain with the techniques to be learned at the host institutions: dynamic modeling in Princeton University (USA) and uncertainty/sensitivity analysis in University of Bergen (Norway). My project will specifically tackle two questions: 1) Which attributes of ISs scale with size? 2) How does a change in size condition the behavior of ISs against shocks?. This research project will turn me into one of the most transdisciplinar, comprehensive specialists on irrigation systems on the international scene, and will yield highly relevant results for both the scientific and policy-making community: it will increase our knowledge on size as a universal constraint, and endow us with better understanding of the risks and benefits associated with the creation/management of small and large irrigation systems.;276330,6;276330,6;H2020-MSCA-IF-2017;/MSCA-IF-GF;UNIVERSITETET I BERGEN;NO;;;;0;1;0;0;0;1 210903;715146;ENERGY ETHICS;SIGNED;H2020-EU.1.1.;ERC-2016-STG;H2020;The Ethics of Oil: Finance Moralities and Environmental Politics in the Global Oil Economy;2017-07-01;2022-06-30;;"In October 2014, the Chairman of the Bank of England Mark Carney warned that many oil reserves cannot be developed. If so, they would contribute so significantly to increased greenhouse gas emissions that international targets to avoid dangerous levels of global warming would be exceeded. However, stock valuations of oil companies assume that all proven and probable reserves can indeed be produced. Amounting to a potentially enormous debt overhang, the Bank of England has launched an enquiry into the threat of a crisis similar to the subprime mortgage crash, known as the ‘carbon bubble’. This looming crisis with its ‘stranded assets’ raises urgent questions about the conflicting dynamics between finance moralities and environmental politics at a time of oil dependency and an uncertain climate future. Grounded in ethnographic fieldwork with oil companies in the US and Norway, energy analysts in the UK and the US, and fossil fuel divestment movements in Germany and the UK, ENERGY ETHICS will develop a new framework for understanding the relationship between oil, money and climate change that counters the prevalent tendency to interpret these issues through aggregated normative systemic analysis only. Taking its starting point in people’s own perceptions of and direct involvement in the oil economy, it will offer a major step forward in understanding how people in positions of influence within the oil economy make financial and ethical valuations of oil. This will contribute to public stakeholder dialogue and wider transdisciplinary engagements. Focusing on oil and its financialization, ENERGY ETHICS has three main research objectives: 1) to examine how people positioned strategically in relation to the global production of oil conceptualise and influence the oil market; 2) to understand the linkages and frictions between these different valuations of oil; and 3) to investigate how oil valuations relate to political reforms and new climate economic initiatives.";1498052;1498052;ERC-2016-STG;/ERC-STG;THE UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS;UK;;;;0;1;0;0;0;1 208789;715950;SHARE;SIGNED;H2020-EU.1.1.;ERC-2016-STG;H2020;Seizing the Hybrid Areas of work by Re-presenting self-Employment;2017-09-01;2022-08-31;;"SHARE is a transdisciplinary and multi-method study of the work arrangements which destabilize the dichotomies between standard and non-standard work and between self-employment and dependent employment. More specifically, it will research solo self-employment, namely self-employment without employees. This is a growing contractual category in Europe which comprises very different subjects, often disguised by statistics and difficult to represent by unions: from independent professionals to ‘fake self-employed’ workers legally self-employed but in fact wholly dependent on the company. Therefore, I introduce the concept of ‘hybrid areas of work’ to refer to the co-existence of features usually attributed to categories traditionally kept sharply distinct. SHARE will study the emergence of hybrid areas of work through comparative research in six European countries: Germany, France, the Netherlands, Italy, UK and Slovakia. Despite the overall large increase of solo self-employment, path-dependency connected to welfare state traditions has induced national legislators to adopt distinct strategies of labour-market (de-)regulation and adjustment of social security systems, producing different consequences on both social protection and collective bargaining. The research programme will make a significant contribution to the advancement of studies on work, employment and industrial relations by moving towards a theoretical rethinking of the categories used hitherto to interpret work and employment. It will combine comparative analysis of labour laws and labour force surveys, both at the EU and national level, with a cross-national ethnography able to inform both macro and legal perspectives with an on-the-ground approach to the forms of collective representation of solo self-employment. By researching how the solo self-employed are classified, measured, and represented, SHARE will furnish societally relevant findings, thus providing both theoretical and applied advancement.";1258250;1258250;ERC-2016-STG;/ERC-STG;UNIVERSITY OF LEEDS;UK;;;;0;1;0;0;0;1 203461;703829;ACTECH;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Ancient ConstructionTECHniques between East and West. Building traditions, technological innovations and workmanship circulation: from Roman Arabia to Medieval Europe.;2017-03-01;2019-02-28;;"This proposal is designed to study the circulation of ancient construction knowledge in the Mediterranean through an innovative and multidisciplinary approach to the analysis of built heritage. Particular attention will be given to the study of a specific construction technique, the arch, and how it influenced the types and techniques of architectural construction between the 2nd and 8th centuries AD, starting in the territories of the Southern Hawr?n (nowadays Jordan and Syria), where the Hellenistic-Nabataean, Roman-Byzantine, Parthian-Sasanian and early Islamic architectural cultures met and influenced each other. In this fertile basin of local experiences, new building techniques and architectural typologies developed and from there spread throughout the Mediterranean basin. The transdisciplinary approach of the project will also allow an in-depth and innovative study of the phenomena behind the ancient construction processes, in terms of relationships between commissioners and workers, workforce and the specific construction techniques employed. The application of new digital technologies will be fundamental for the success of the project; in particular, a web-based GIS will be implemented to record the vertical surfaces, and an operational protocol for three-dimensional architectural survey will be developed, via which photographic-quality virtual reconstructions of built heritage will be generated by integrating digital photogrammetry and laser scanner. New technologies will also play a fundamental role in the presentation and diffusion of the data thanks to a fully open-access philosophy in which the results will be made available not only to the scientific community but also to the general public. Conceived as such, the project will be fundamental for both the proposer and the host institution, and it will contribute concretely to European excellence and competitiveness in the creation of a common, current and widespread Euro-Mediterranean culture.";173076;173076;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;UNIVERSITE PARIS I PANTHEON-SORBONNE;FR;;;;0;1;0;0;0;1 219121;825392;RESHAPE;SIGNED;H2020-EU.3.1.3.;SC1-BHC-09-2018;H2020;Reshaping undesired Inflammation in challenged Tissue Homeostasis by Next-Generation regulatory T cell (Treg) Approaches – from Advanced Technology Developments to First-in-Human Trials;2019-01-01;2022-12-31;;"Adoptive transfer of regulatory T cells (Treg) is a promising new therapeutic option to reshape undesired intra-tissue immune imbalance in immune-related disease entities. It supports long-term function of allografts and use of Advanced Therapy Medicinal Products (ATMP) by overcoming the challenge of unwanted immune reaction by the recipient of the ATMP. Therefore, adoptive Treg therapy is a potential game changer in health care, particularly in immune diseases, organ & hematopoietic stem cell (HSC) transplantation, and regenerative medicine, including gene therapy. Based on the Triple-T concept - Transdisciplinarity, Technology, Translation - the major goal of RESHAPE is to transform the treatment of patients suffering from undesired immunity/inflammation, who presently have limited curative treatment options, by applying novel Treg approaches that overcome the limitations of 1st generation Treg product developments. Members of the consortium, with academic & biotech backgrounds, are pioneers in the development of Treg therapy from basic science to very recent encouraging First-In-Human (FIH) clinical trials of the 1st generation Treg products. They have a longtrack record of collaboration, including in EC-funded projects. The first clinical trials were performed to combat organ transplant rejection and Graft-versus-Host-Disease. However, promising preclinical studies offer a broad application field of Treg therapy beyond allotransplantation. Based on our preclinical & clinical data, we have identified several opportunities for improving Treg therapy, such as enhanced antigen specificity & functional stability, and recipient conditioning, that will be addressed by RESHAPE. The next-generation Treg products, developed by advanced technologies including CRISPR/Cas9, will be tested on platforms applying new methods for cell characteristics in both in vivo /in vitro models, and finally proven in FIH-clinical trials accompanied by biomarker and health economic studies";13137396,25;13137396,25;H2020-SC1-2018-Single-Stage-RTD;/RIA;CHARITE - UNIVERSITAETSMEDIZIN BERLIN;DE;"NATURWISSENSCHAFTLICHES UND MEDIZINISCHES INSTITUT AN DER UNIVERSITAET TUEBINGEN;MEDIZINISCHE HOCHSCHULE HANNOVER;INNOVATION ACTA S.R.L.;TXCELL;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;TISSUSE GMBH;CELL THERAPY CATAPULT LIMITED;CENTRE HOSPITALIER UNIVERSITAIRE DE NANTES";"DE;IT;FR;UK";;0;1;0;0;0;1 194996;654796;SAAB;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2014-GF;H2020;'Science as Applied to Building' : Science, Construction, and Architectural Acoustics (1914-1954);2015-07-01;2018-09-28;;The aim of this Fellowship is for the researcher, Dr Fiona Smyth, to develop the professional prowess, advanced training, interdisciplinary skills, high-impact dissemination, and practical experience commensurate with a leading independent researcher in the EU. The remit of the Fellowship research falls under the categories of history of science, history of construction and architectural acoustics. The researcher will be based for two years in the Dept. of the History of Science in Harvard University, working under the supervision of Professor Peter Galison. The third year of the Fellowship will be completed in the Acoustics Research Group in the School of Engineering, Trinity College Dublin (TCD) working under the supervision of Professor Henry Rice. Research training will be implemented through an interdisciplinary project investigating the 20th century emergence of architectural acoustics as a branch of modern building science in Britain and Ireland. On the outgoing phase of the Fellowship the researcher will access expertise, advanced training and mentoring in the History of Science. No Irish university has yet established a dedicated History of Science department. In the return phase the researcher will consolidate the knowledge and experience gained in the US through advanced laboratory training in acoustics. In TCD she will be given the opportunity to embed her new knowledge in the design of interdisciplinary curricula for graduate students. Under the guidance of international experts, she will acquire an invaluable skill-set bridging humanities, science and technology with implications for contemporary societal and economic application. The resources of the host departments will facilitate development of an interdisciplinary and international academic network as well as career mentoring. The Fellowship will establish the researcher firmly at the centre of interdisciplinary research in the histories of building science and architectural acoustics.;266063,4;266063,4;H2020-MSCA-IF-2014;/MSCA-IF-GF;THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN;IE;;;;1;0;0;5;0;0 214449;796998;Constr-HaVi;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Construction techniques, experimentation and innovative architectural solutions atHadrian’s Villa (Tivoli, Italy);2019-07-01;2021-06-30;;The aim of this Fellowship is to develop the professional prowess, advanced training, interdisciplinary skills, high-impact dissemination, and practical experience commensurate with a leading independent researcher in the EU. The aim of the project is to investigate the building and engineering techniques utilized in constructing Hadrian’s Villa. For the first time, I will apply a new research approach to a comprehensive study of the villa that concentrates not only on architectural design and form but also on building materials, construction techniques and engineering. The main objective is to create a synthesis combining analysis of the buildings with a critical study of the bibliography that will result in a comprehensive corpus of the building solutions found in the different structures across the entire site. I will be based in the Department of Classics in Trinity College Dublin (TCD), working under the supervision of Professor Hazel Dodge. Research training will be implemented through an interdisciplinary project investigating the ancient architectural process of construction. I will access expertise, advanced training and mentoring in the History of architecture. No Irish university, but Professor Dodge, has yet established a dedicated History of the roman architecture. In TCD I will be given the opportunity to embed new knowledge in the design of interdisciplinary curricula for graduate students. Under the guidance of international experts, I will acquire an invaluable skill-set bridging humanities, science and technology with implications for contemporary conservation of cultural heritage. The resources of the host departments will facilitate development of an interdisciplinary and international academic network as well as career-mentoring. The Fellowship will establish me firmly at the centre of interdisciplinary research in the histories of building science.;175866;175866;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN;IE;;;;1;0;0;5;0;0 209519;742339;ERA;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Expanding Rights in an Age of Retrenchment: Women, Social Movements and the Politics of Family Leave;2017-09-04;2019-09-03;;"Recent innovations in family policy extend parental leave benefits to fathers and establish paid family leave to care for non-child relatives, such as spouses and parents. Such policies seek to ease work-life tensions, yet there are considerable cross-country differences in the existence, duration and generosity of paid parental and family leave benefits. While welfare state theories offer several explanations for cross-country differences in family policies, we have few explanations for policy content – who is included and excluded from provisions – and the timing of policy change. ERA will apply a unique, recursive mixed-method approach to understand the nature and extent of interactions between various key actors, such as representatives from government, organized labor, women’s movements and organizations opposed to reform, and how such interactions shape family policies. While my quantitative approach will consider the timing of parental leave policy adoption, my qualitative approach will focus on how specific family members – particularly non-child relatives – become incorporated under leave law. Analysis will combine insights from interdisciplinary fields of social movement outcomes (in sociology) and comparative policy analysis (in sociology and political science) and make theoretical contributions to both fields. ERA is a cross-sectoral, interdisciplinary and gender-mindful project that includes end-users in project implementation and an ambitious dissemination, communication and outreach strategy. I bring close to 10 years of experience working in interdisciplinary research centers, publishing independently and with collaborators and expertise in social movements and mixed methods. Collaboration with researchers at the interdisciplinary Swedish Institute for Social Research promises new competencies in policy research and comparative policy analysis and will result in a new, publicly accessible data module, facilitating future cutting-edge research.";185857,2;185857,2;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;STOCKHOLMS UNIVERSITET;SE;;;;1;0;0;4;0;0 201594;708249;GATED;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-GF;H2020;Segregated education in post-conflict Bosnia and the possibilities of future conflicts in Europe;2016-10-01;2019-09-30;;The aim of this Fellowship is to provide Dr Maja Halilovic-Pastuovic with advanced interdisciplinary training and new skills and experience in order to enhance her innovative and creative potential, increase her knowledge base, expand her career possibilities and enable her to reach professional maturity commensurate with a leading researcher in the EU. The remit of the Fellowship falls under the categories of transformation of societies, interethnic relations, and education: systems and institutions. The researcher will be based for two years at the Josef Korbel School, University of Denver, working under the supervision of Professor Timothy Sisk. The return phase of the Fellowship will be completed in the Irish School of Ecumenics at Trinity College Dublin under the supervision of Prof Etain Tannam. Research training will be implemented through an interdisciplinary project investigating segregated education in Bosnia and Herzegovina and security in Europe. The specific aim of the project is to investigate if segregated education in post-conflict societies causes radicalisation of youth and increases the possibilities of future conflicts. The Researcher is a trained sociologist and the exposure to the University of Denver whose expertise lies in the field of international relations and political science, and to Trinity College Dublin where expertise is focused on peace studies, will provide the researcher with interdisciplinary training necessary for advancement of her career and the success of the project. The resources of the two host institutions will facilitate the development of an international academic network, as well as career mentoring, and will firmly establish the researcher at the centre of the transnational interdisciplinary nexus addressing the challenge of European security.;248063,4;248063,4;H2020-MSCA-IF-2015;/MSCA-IF-GF;THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN;IE;;;;1;0;0;4;0;0 205492;721916;TTIP-ITN;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2016;H2020;TRANSATLANTIC TRADE AND INVESTMENT PARTNERSHIP-INTERNATIONAL TRAINING NETWORK;2017-04-01;2021-03-31;;The EU currently is negotiating a controversial Transatlantic Trade and Investment Partnership (TTIP) agreement with the USA, the main features of which will be the abolition of tariffs, the reduction of non-tariff barriers to trade between the EU and the USA and the introduction of a dispute settlement mechanism. The objective of the proposed TTIP Innovative Training Network (TTIP-ITN) is to foster interdisciplinary research into TTIP with a view to create a significantly increased European knowledge base and research capacity on TTIP, thus helping Europe to reap the benefits of TTIP (wealth, jobs, etc.) while addressing its challenges (democracy, accountability, environmental- and labour standards, etc.).The network is an interdisciplinary, intersectoral collaboration pooling world-leading researchers and practitioners from all relevant disciplines of law - EU constitutional, internal market, and external relations law, international trade law, and international law, as well as political science, international relations, business studies, and economics. TTIP-ITN fully integrates non-academic Beneficiaries and Partner Organisations, including think tanks, lobbyists, regulatory bodies, law firms, US academic institutions, and an international organisation. Furthermore, the network will support and enhance the process of converting research results into policy papers through partnership with high-impact policy research units at the forefront of European policy research and policy making. The work package consists of 3 substantive work packages on (1) transatlantic governance, (2) transatlantic regulation, and (3) multilateralism and regionalism. 15 PhD research projects will be supervised by academics of the 11 Beneficiaries with an interdisciplinary training programme covering the legal, political and economic foundations of TTIP and an interdisciplinary and intersectoral programme of secondments involving 22 Partner Organisations.;3910777,56;3910777,56;H2020-MSCA-ITN-2016;/MSCA-ITN-ETN;THE UNIVERSITY OF BIRMINGHAM;UK;"EGMONT - INSTITUT ROYAL DES RELATIONS INTERNATIONALES;IFO INSTITUT LEIBNIZ INSTITUT FUR WIRTSCHAFTSFORSCHUNG AN DER UNIVERSITAT MUNCHEN EV;CENTRE D'ETUDES PROSPECTIVES ET D'INFORMATIONS INTERNATIONALES;UNIVERSITA DEGLI STUDI DI TORINO;CITY UNIVERSITY OF LONDON;GERMAN UNIVERSITY OF ADMINISTRATIVE SCIENCES;EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH;THE UNIVERSITY OF NOTTINGHAM;ERASMUS UNIVERSITEIT ROTTERDAM;UNIVERSITAT PASSAU;CENTRE D'INFORMATION ET DE RECHERCHE SUR L'ECONOMIE MONDIALE";"BE;DE;FR;IT;UK;CH;NL";;1;0;0;4;0;0 193885;642116;SDIN;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2014-ETN;H2020;Service Design for Innovation;2015-01-01;2018-12-31;;"Service Design for Innovation (SDIN)-ETN aims to integrate service design and service innovation approaches that are now dispersed into an innovative research training framework; doing so leverages the creative power of service design to foster innovation. Specific objectives are: creating a mass of researchers who can drive widespread application of service design to leapfrog innovation in European organisations; and developing interdisciplinary competences in the key SDIN area and in key service sectors -ICT, public services and utilities. SDIN training programme comprises: individual research projects with interdisciplinary supervision (design and management) and non-academic involvement; substantial non-academic training (through hosts and secondments); development of competences in at least one key service sector, with exposure to other sectors; and network wide training with innovative courses, workshops, transferable skills training, and network wide training events. A strong consortium with unique combination of expertise will implement SDIN. Academic beneficiaries provide a rich training experience and research competences in service design and service innovation. The three non-academic beneficiaries are innovation leaders in ICT, public services and utilities, providing a rich ground for application of SDIN results to multiple sectors. SDIN will have significant impacts on ESRs, partners, and the pursuit of the Innovation Union: SDIN will develop interdisciplinary and multi sectorial competences in ESRs, which are highly valued and have a strong innovation impact on organisations. Beneficiaries will integrate their expertise to build enduring interdisciplinary and multi-sector competences in SDIN. SDIN’s extensive dissemination will ensure that the results achieved are shared with wider communities, thus producing spill over effects to other sectors. SDIN can make a significant and timely contribution to the Innovation Union strategy.";2283926,12;2283925,68;H2020-MSCA-ITN-2014;/MSCA-ITN-ETN;UNIVERSIDADE DO PORTO;PT;"LINKOPINGS UNIVERSITET;Värmlands läns landsting;UNIVERSITEIT MAASTRICHT;EDP COMERCIAL-COMERCIALIZACAO DE ENERGIA SA;LANCASTER UNIVERSITY;POLITECNICO DI MILANO;TECHNISCHE HOCHSCHULE KOLN;KARLSTADS UNIVERSITET";"SE;NL;PT;UK;IT;DE";;1;0;0;4;0;0 201684;713606;I4FUTURE;SIGNED;H2020-EU.1.3.4.;MSCA-COFUND-2015-DP;H2020;Novel Imaging and Characterisation Methods in Bio, Medical, and Environmental Research and Technology Innovations;2016-04-01;2021-03-31;;The I4Future Programme is a novel international, interdisciplinary and inter-sectoral doctoral programme hosted at the University of Oulu. The programme is based on full exploitation of the possibilities of modern imaging and characterisation methods in cross-disciplinary work. The unique training programme aims to respond to the increasing need for skilled next-generation ESRs in the changing and demanding European job markets in industry, the public sector and academia. I4Future brings together the complementary and supplementary expertise of world-class researchers in training ESRs with interdisciplinary visions in highly relevant socio-economic research areas and state-of-the-art techniques. I4Future combines five faculties and 17 research groups of UOULU, driven together with eight international universities and nine private companies from the paper, steel, mining and medical industries as well as appliances manufacturing and four multidisciplinary public sector organisations. The I4Future programme will provide 20 ESRs with a first-hand understanding of how research develops from basic science findings to interdisciplinary innovations and commercially valuable applications. The programme exploits local, national and international strengths of the network partners at multiple levels: excellence in research, local and European cutting-edge infrastructures, collaboration networks and secondments, and wide dissemination and outreach. I4Future builds upon a critical mass of interdisciplinary, inter-sectoral and international expertise and provides a unique combination of complementary methodological approaches for high-quality training that would not be possible to implement at any site or organisation alone.;4185600;2092800;H2020-MSCA-COFUND-2015;/MSCA-COFUND-DP;OULUN YLIOPISTO;FI;;;;1;0;0;4;0;0 193957;642877;InnoChain;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2014-ETN;H2020;Building Innovation in the Extended Digital Chain;2015-09-01;2019-08-31;;"The InnoChain ETN network is a shared research training environment examining how advances in digital design tools challenge building culture enabling more sustainable, more informed and more materially smart design solutions. The network aims to train a new generation of interdisciplinary researchers with a strong industry focus that can effect real changes in the way we think, design and build our physical environment. The programme investigates the extended digital chain as a particular opportunity for interdisciplinary design collaboration. Challenging the traditional thinking of design as a linear process of incremental refinement, InnoChain identifies three axes of design innovation potential communication, simulation and materialisation appearing as distributed and interdisciplinary activities across the design chain. Situating feedback between design processes as a key concern for developing holistic and integrated design methods, the network will develop new interdisciplinary design methods that integrate advanced simulation and interface with material fabrication. With a strong inter-sector focus, InnoChain connects “research in practice” with “research in academia”. Assembling 6 internationally recognised academic research environments leading research into computational design in architecture and engineering and 14 innovation pioneering industry partners from architecture, engineering, design software development and fabrication, the programme will establish a shared training platform for 15 early stage researchers. The network creates a structured training programme focussed on supervision of individual research projects, an inter-sector secondment programme as well as collective research events including workshop-seminars, colloquia, summer school and research courses that provide a unique opportunity for young researchers to obtain new knowledge and skills positioning them between strong innovative research practice and influential industrial impact.";3972691,44;3972691,44;H2020-MSCA-ITN-2014;/MSCA-ITN-ETN;DET KONGELIGE DANSKE KUNSTAKADEMIS SKOLER FOR ARKITEKTUR, DESIGN OG KONSERVERING.;DK;"KUNGLIGA TEKNISKA HOEGSKOLAN;UNIVERSITAT FUR ANGEWANDTE KUNST WIEN;UNIVERSITAET STUTTGART;INSTITUT D'ARQUITECTURA AVANCADA DE CATALUNYA;UNIVERSITY COLLEGE LONDON";"SE;AT;DE;ES;UK";;1;0;0;4;0;0 217977;812997;Cleopatra;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2018;H2020;Cross-lingual Event-centric Open Analytics Research Academy;2019-01-01;2022-12-31;;"With a rapidly increasing degree of integration among the European countries, a rising number of events, such as Paris shootings and Brexit, strongly impact the European community and the European digital economy across language and country borders. This development results in a vast amount of event-centric multilingual information available from different communities in the news, on the Web and in social media. Cross-lingual technologies to efficiently access, analyse and interact with this information are of utmost importance for various stakeholder groups across Europe, including digital humanities, memory institutions, publishers, media monitoring companies and journalists. The Cleopatra ITN offers a unique interdisciplinary and intersectoral research and training programme addressing these challenges. The main objectives are to: 1) Facilitate advanced cross-lingual processing of event-centric textual and visual information on a large scale; 2) develop innovative methods for efficient and intuitive user access and interaction with multilingual information; 3) facilitate large-scale analytics of multilingual event-centric information and cross-cultural studies; 4) educate a group of top-level scientists with unique interdisciplinary and intersectoral expertise in multilingual information science who will be enabled to take leading roles in research and industry in the future; and 5) establish an interdisciplinary curriculum for cross-lingual information analytics. The main outcomes of Cleopatra include: 1) novel methods for event-centric cross-lingual processing; 2) highly innovative user interaction paradigms for multilingual information; 3) open large-scale data sets and software components for a variety of EU languages; and 4) an interdisciplinary curriculum and educational materials. Overall, Cleopatra will contribute to the European digital economy in several application domains and strengthen the European position in multilingual information science.";3949688,52;3949688,52;H2020-MSCA-ITN-2018;/MSCA-ITN-ETN;GOTTFRIED WILHELM LEIBNIZ UNIVERSITAET HANNOVER;DE;"INSTITUT JOZEF STEFAN;UNIVERSITY OF LONDON;RHEINISCHE FRIEDRICH-WILHELMS-UNIVERSITAT BONN;TECHNISCHE INFORMATIONSBIBLIOTHEK (TIB);UNIVERSITY OF SOUTHAMPTON;SVEUCILISTE U ZAGREBU FILOZOFSKI FAKULTET;UNIVERSITEIT VAN AMSTERDAM";"SI;UK;DE;HR;NL";;1;0;0;4;0;0 202145;702257;COLEDISO;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Corporate Legitimacy in Digital Society: The Role of Citizens’ Judgments in Social Media;2016-07-15;2018-07-14;;Corporate legitimacy, defined as the social acceptance of corporate behaviour, is constructed through a process of public deliberation. In recent years, social media technologies have enabled citizens to participate in this public deliberation by discussing, critiquing, and praising corporations. Management research about corporate legitimacy, however, has so far mainly taken into account the judgments of institutional evaluators, such as news media. By drawing on communication theories and an innovative method that combines sentiment analysis with discourse analysis of social media data, this interdisciplinary research project will examine thousands of citizens’ voices and their role in the process of legitimacy construction in digital society. The Researcher will be embedded within the vibrant research environment of the ETHOS Centre at the Cass Business School of the City University London, an institution with an excellent portfolio in education that is uniquely positioned academically and geographically. The research programme will provide access to academic expertise in an interdisciplinary environment as well as new research experience and training, providing an outstanding researcher with theoretical knowledge, methodological skills, and contact networks that will enable him to develop into a key contributor to international research in the interdisciplinary field of Corporate Social Responsibility (CSR). Thus far, the Researcher has published recent, high ranked journal publications that apply quantitative research methods. Through the acquirement and application of a qualitative method, more particularly discourse analysis, and collaboration with world-leading experts in legitimation processes, this research programme will propel the Researcher to the forefront of an interdisciplinary field emerging within management science and communication science. It will enable him to produce high quality research and to engage the general public with a lasting impact.;195454,8;195454,8;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;CITY UNIVERSITY OF LONDON;UK;;;;1;0;0;4;0;0 218148;786479;MAREITA;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Mapping Remediation in Italian Literature Beyond the Digital Revolution;2018-10-01;2020-09-30;;The aim of this Fellowship is to develop a strong academic profile by improving my publications record and working in highly interdisciplinary research environments, so as to establish myself as a leading voice in the research on the interconnections between literary and electronic culture and to secure a permanent academic position at a European university. I will carry out my research at the School of Languages, Literature and Cultural Studies at Trinity College Dublin, under the supervision of Dr Clodagh Brook. My project investigates the intermedial dialogue between Italian literature, from the mid-1950s up to the present day, and electronic media. I will combine interdisciplinary critical analyses of literary texts with Social Network Analysis and a quantitative approach to the phenomenon of remediation in literature. The main outputs will be a monograph dedicated to the subject and a website hosting the SNA graphs resulting from my work. Two main research training components will allow me to achieve my goals: I will gain expertise in interdisciplinary research applied to literature through Dr Brook’s mentorship and thanks to the collaboration with the AHRC-funded research project ‘Interdisciplinary Italy 1900-2020: Interart/Intermedia’, for which Dr Brook is the Primary International Investigator. The opportunity to be a part of this research team—the only one currently working on the topic—will allow me to hone my research skills and develop my professional network. Secondly, I will improve my coding skills and learn how to create and analyse network graphs using the necessary software by collaborating with the Centre for Digital Humanities at the Trinity Long Room Hub Arts & Humanities Research Institute. Not only has the Centre an international reputation and vast expertise, but its ongoing project K-PLEX (Horizon 2020) on Humanities and big data shares some of my research aims and methodology, thus opening up possibilities for a fertile collaboration.;175866;175866;H2020-MSCA-IF-2017;/MSCA-IF-EF-RI;THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN;IE;;;;1;0;0;4;0;0 203186;713730;TLRH-VRF COFUND;SIGNED;H2020-EU.1.3.4.;MSCA-COFUND-2015-FP;H2020;Trinity Long Room Hub Visiting Research Fellows COFUND programme;2016-06-01;2020-10-31;;"The Trinity Long Room Hub Visiting Research Fellows Programme will offer opportunities to nine Experienced Researchers from across the spectrum of the Arts and Humanities to spend a fellowship of 12 months duration at Trinity Colleges’ Arts and Humanities Research Institute. This fellowship programme represents a significant enhancement of the offering of the existing fellowship programme operating in the TLRH. The objectives of the programme are to attract high quality international researchers from Europe and all over the world via more attractive employment conditions including an employment contract and via wide and rigorous promotion of the calls while open. The programme will provide fellows with training and networking opportunities that will enhance their career development potential ( via their involvement in the activities of an Interdisciplinary College Research Theme affiliated to the Long Room Hub under which they will be recruited and access to a range of non research related training opportunities via different units in TCD); to identify the relevance of their work for other sectors outside academia including the public ( via the inclusion of a secondment element in the programme and via participation in the public engagement activities of the Long Room Hub) and to provide them with interdisciplinary research opportunities( again via involvement in and exposure to staff active in the Interdisciplinary Research Theme under which they have been recruited). The Interdisciplinary Research Themes involve staff across a TCD schools not only thoseaffiliated to the TLRH (i.e. Computer Science and Statistics, Engineering, Nursing, Social Work and Psychology) that will hopefully stand them in good stead as they seek to expand their academic networks. Finally Trinity College and the Long Room Hub will support the selection of researchers following an open, merit-based and impartial and equitable selection procedure, based on international peer review.";637200;318600;H2020-MSCA-COFUND-2015;/MSCA-COFUND-FP;THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN;IE;;;;1;0;0;4;0;0 212796;759457;FAIRFISH;SIGNED;H2020-EU.1.1.;ERC-2017-STG;H2020;Hidden Hunger, Forgotten Food;2018-02-01;2023-01-31;;"Food Security is a grand challenge of our time, but three factors inhibit our ability to meet global targets. First, interdisciplinary approaches incorporating ecological, social, and health sciences are fundamental, but lacking. Second, a disproportionate focus on food quantity overlooks ‘hidden hunger’, or micronutrient deficiencies, which are implicated in over a million deaths annually. Third, small-scale fisheries (SSF) reach 100s of millions of people in the developing world, hold potential for achieving food security, but remain ‘forgotten food’ in global discourse. Consequently, an interdisciplinary approach that tackles hidden hunger within SSF is a critical frontier for food security research. Fish are particularly high in many micronutrients, but a systematic understanding of which species have the greatest concentrations of key nutrients is needed. Inadequate access to nutritious food is one of the most significant problems of the modern age, which can be illuminated through analyses of power. The failure to realise the tremendous potential for improving food security through fisheries stems from a lack of understanding of how social drivers exacerbate or ameliorate nutritional inequalities. Consequently, an in-depth analysis that quantifies how key social drivers impact nutritional inequality, is essential. FAIRFISH will address these gaps to uncover the ecological and socio-cultural determinants of the contributions SSF make to human health: 1. Establish the ecological and environmental determinants of nutrient availability among fish species using a traits based approach. 2. Advance social practice theory, by integrating an analysis of power, to determine what power relations enable or constrain access to nutritious food. 3. Progress interdisciplinary science, by integrating findings from 1 and 2, to quantify the impact of key social drivers on nutritional inequality, and uncover opportunities to meet nutritional needs.";1493605;1493605;ERC-2017-STG;/ERC-STG;UNIVERSITY OF LANCASTER ROYAL CHARTER;UK;;;;1;0;0;3;0;0 213023;778308;SPINMULTIFILM;SIGNED;H2020-EU.1.3.3.;MSCA-RISE-2017;H2020;Physical principles of the creation of novel SPINtronic materials on the base of MULTIlayered metal-oxide FILMs for magnetic sensors and MRAM;2018-01-01;2021-12-31;;"The main goal of the project is the elaboration of research and development principles and technology, as well as creation of novel nanoheterostructures for application in spintronic devices, first of all, in magnetic field sensors and magnetoresistive random access memories. The key research and technological aspects are focused on the formation of layers and/or nanosized grains of a ferromagnetic material with an ultimate degree of conduction electron spin polarization, separated by dielectric interlayers. The main research, technological and innovation aspects of the work are aimed at an increase of the devices’ sensitivity to magnetic fields thanks to the high degree of spin polarization and to the magnetoresistance due to electron quantum tunneling through dielectric barriers. The proposed creation methods of the device prototypes can be rapidly implemented in the automotive, electronic and biomedical industries by means of a rather simple technology, which makes them attractive for the industry across the EU, as only the standard technological equipment is used. The new generation spintronic devices to be developed in the present project will possess high sensitivity, speed performance and low energy consumption. The project aims as well at the creation of a stimulating and interdisciplinary training partnership, with actors from the academia and private sector, promoting the exchange of ideas, methods, techniques as well as enabling an accelerated technology transfer from science to industry through a continuous collaboration between the stakeholders. Working on spintronics demands strongly innovative and interdisciplinary skills, since there is a lot of pressure from the private sector to develop new original solutions for the modern devices. Training of the high-level personnel possessing complementary interdisciplinary skills is thus a key issue.";558000;558000;H2020-MSCA-RISE-2017;/MSCA-RISE;UNIVERSIDADE DE AVEIRO;PT;"VRIJE UNIVERSITEIT BRUSSEL;WMT WIRE MACHINE TECHNOLOGIES LTD;KAUNO TECHNOLOGIJOS UNIVERSITETAS;INSTITUTE OF MAGNETISM OF THE NATIONAL ACADEMY OF SCIENCE OF UKRAINE AND THE MINISTRY OF EDUCATION AND SCIENCE OF UKRAINE;TECHNISCHE UNIVERSITAET DRESDEN";"BE;IL;LT;UA;DE";;1;0;0;3;0;0 193882;642069;HPC-LEAP;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2014-EJD;H2020;High Performance Computing in Life Sciences, Engineering And Physics;2015-04-01;2019-03-31;;Progress in computers and algorithms in the last years has made numerical simulation and modelling a key research methodology in both academia and industry, which in turn drives exascale computing in order to maintain excellence in research and innovation. A disruptive evolution in computer technologies is required for attaining exascale performances in the coming years bringing challenges that urgently need to be addressed across science and engineering fields. Therefore new interdisciplinary strategies are required in order to educate the next generation of scientists to address such challenges enabling them to be at the forefront of their respective research fields. Instead of the traditional domain-specific training, integrated approaches are needed that can be best implemented by collaborative networks of universities, research institutes and industrial partners. We propose a highly interdisciplinary joint doctorate program realized by bringing together world-leading experts in applied mathematics, high performance computing technologies, particle and nuclear physics, fluid dynamics and life sciences to appropriately train researchers in Europe to exploit high performance computing, advance science and promote innovation. Students will be trained in mathematical and computational concepts underpinning current and future numerical simulations in turbulent flows, computational biology and lattice quantum chromodynamics. The research projects are designed to enhance collaborations and interactions across these disciplines, integrating non-academic partners, and to develop methodologies that efficiently use large-scale numerical simulations on future high performance computer systems. Students who complete this training program will be versatile to undertake highly interdisciplinary projects, well positioned to embark on a successful career in academia or the industrial sector.;3667663,72;3667663,72;H2020-MSCA-ITN-2014;/MSCA-ITN-EJD;THE CYPRUS INSTITUTE;CY;"UNIVERSITA DEGLI STUDI DI ROMA TOR VERGATA;RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN;BERGISCHE UNIVERSITAET WUPPERTAL;UNIVERSITY OF CYPRUS;TECHNISCHE UNIVERSITEIT EINDHOVEN;UNIVERSITA DEGLI STUDI DI FERRARA";"IT;DE;CY;NL";;1;0;0;3;0;0 205366;708658;DANTE;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-GF;H2020;Use of novel techniques to identify pathogenic versus non-pathogenic TH17 cells in experimental autoimmune encephalomyelitis, a murine model of multiple sclerosis.;2016-10-01;2020-09-29;;The aim of this Fellowship is for the researcher, Dr Karen Dixon, to receive advanced training, develop interdisciplinary skills with high-impact dissemination, and practical experience in line with a leading independent researcher in the EU. The remit of the Fellowship proposal falls under the category of Immunology- autoimmunity and TH17 cell biology. The researcher will be based for two years in the laboratory of Professor Vijay Kuchroo at Brigham & Women`s Hospital. The third year of the Fellowship will be completed in the Department of Biochemistry & Immunology, Trinity College Dublin (TCD) working under the supervision of Professor Kingston Mills. Research training will be implemented through an interdisciplinary project investigating the mechanism by which IL-23 regulates the development of pathogenic vs non-pathogenic TH17 cells. On the outgoing phase of the Fellowship, the researcher will access expertise, state-of-the-art training and mentoring in deciphering the heterogeneity of TH17 cells using advanced transcriptional analysis. In the return phase the researcher will consolidate the knowledge and experience gained in the US through further laboratory training in IL-17 mediated disease. In TCD she will be given the opportunity to embed her new knowledge in Ireland through mentoring and teaching in the host institute. This includes practical seminars on state of the art technology including single cell RNA-seq and NanoString technology. Under the guidance of international experts, she will acquire an invaluable skillset using the latest technical advances to decode heterogeneous populations in immune mediated diseases. The resources of the host departments will facilitate development of an interdisciplinary and international academic network as well as career-mentoring. With increasing recognition of the functional heterogeneity within cell populations, this Fellowship will establish the researcher firmly at the centre of immunological research in the EU.;248063,4;248063,4;H2020-MSCA-IF-2015;/MSCA-IF-GF;THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN;IE;;;;1;0;0;3;0;0 196914;662268;HoNESt;SIGNED;"H2020-Euratom-1.8.;H2020-Euratom-1.2.;H2020-Euratom-1.4.;H2020-Euratom-1.3.;H2020-Euratom-1.1.";NFRP-12-2014;H2020;History of Nuclear Energy and Society;2015-09-01;2019-02-28;;"HoNESt (History of Nuclear Energy and Society) involves an interdisciplinary team with many experienced researchers and 24 high profile research institutions. HoNESt’s goal is to conduct a three-year interdisciplinary analysis of the experience of nuclear developments and its relationship to contemporary society with the aim of improving the understanding of the dynamics over the last 60 years. HoNESt’s results will assist the current debate on future energy sources and the transition to affordable, secure, and clean energy production. Civil society's interaction with nuclear developments changes over time, and it is locally, nationally and transnationally specific. HoNESt will embrace the complexity of political, technological and economic challenges; safety; risk perception and communication, public engagement, media framing, social movements, etc. Research on these interactions has thus far been mostly fragmented. We will develop a pioneering integrated interdisciplinary approach, which is conceptually informed by Large Technological Systems (LTS) and Integrated Socio-technical System (IST), based on a close and innovative collaboration of historians and social scientists in this field. HoNESt will first collect extensive historical data from over 20 countries. These data will be jointly analyzed by historians and social scientists, through the lens of an innovative integrated approach, in order to improve our understanding of the mechanisms underlying decision making and associated citizen engagement with nuclear power. Through an innovative application of backcasting techniques, HoNESt will bring novel content to the debate on nuclear sustainable engagement futures. Looking backwards to the present, HoNESt will strategize and plan how these suitable engagement futures could be achieved. HoNESt will engage key stakeholders from industry, policy makers and civil society in a structured dialogue to insert the results into the public debate on nuclear energy.";3052269;3052269;NFRP-2014-2015;/RIA;UNIVERSIDAD POMPEU FABRA;ES;"UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6;PLOVDIVSKI UNIVERSITET PAISIY HILENDARSKI;UNIVERSIDAD PUBLICA DE NAVARRA;THE PRESIDENT AND TRUSTEES OF COLBY COLLEGE;UNIVERSITEIT ANTWERPEN;VIESOJI ISTAIGA EUROPOS HUMANITARINIS UNIVERSITETAS;KUNGLIGA TEKNISKA HOEGSKOLAN;THE UNIVERSITY OF SHEFFIELD;THE BOARD TRUSTEES OF THE SCIENCE MUSEUM;ETHNIKO KAI KAPODISTRIAKO PANEPISTIMIO ATHINON;SOCIEDADE PORTUGUESA DE INOVACAO CONSULTADORIA EMPRESARIAL E FOMENTO DA INOVACAO SA;KOBENHAVNS UNIVERSITET;CENTRO DE INVESTIGACIONES ENERGETICAS, MEDIOAMBIENTALES Y TECNOLOGICAS-CIEMAT;DIALOGIK GEMEINNUETZIGE GESELLSCHAFT FUER KOMMUNIKATIONS- UND KOOPERATIONSFORSCHUNG mbH;FORSVARSHOGSKOLAN;ROWE EUGENE JOHN - GENE ROWE EVALUATIONS;UNIVERSITY OF YORK;FRIEDRICH-SCHILLER-UNIVERSITAT JENA;UNIVERSITY OF CENTRAL LANCASHIRE;FEDERAL STATE BUDGETARY INSTITUTION OF SCIENCE INSTITUTE OF HISTORY AND ARCHAEOLOGY OF THE URAL BRANCH OF THE RUSSIAN ACADEMY OF SCIENCES;UNIVERSITAT AUTONOMA DE BARCELONA;TECHNISCHE UNIVERSITEIT EINDHOVEN;DEUTSCHES MUSEUM VON MEISTERWERKEN DER NATURWISSENSCHAFT UND TECHNIK;SORBONNE UNIVERSITE;LAPPEENRANNAN-LAHDEN TEKNILLINEN YLIOPISTO LUT";"FR;BG;ES;US;BE;LT;SE;UK;EL;PT;DK;DE;RU;NL;FI";;1;0;0;3;0;0 197325;669062;BioEcon;SIGNED;H2020-EU.4.c.;WIDESPREAD-2-2014;H2020;New Strategies on Bio-Economy in Poland;2015-07-01;2020-06-30;;"The overall objective of BioEcon is to develop, extend and fully unlock the research potential of IUNG in accordance with the new global strategies trends and changes in national needs through the creation of an excellent international and interdisciplinary department on bio-economy and systems analysis. The knowledge, experience, developed tools, research programme and collaborations will allow the institute to maintain the new unit in the institute also after the completion of the ERA Chairs project, it will operate in close cooperation with the rest of the departments of the Institute, with main purpose being regional development in line with knowledge-based bio-economy. This structural change in IUNG is a response to an identified need and potential on the national level and will receive the support of public authorities, industry and other research structures. The specific objectives of BioEcon are as follows: -Improvement of research organization and management, which includes the administrative and policy structural changes. -Update of Research and innovation strategy, in full compliance with Polish RIS3 and implement a brand new approach of interdisciplinary research performance, aiming to promote and develop bio-economy. -Intensive interaction with policy makers and stakeholders to mobilize regional support, transfer research outcomes and foster the regional development through involvement of all economic actors in a strategic growth path. -Increase research excellence in the field of bio-economy and system analysis through human capacity upgrade, implementation of a training programme, and collaboration with excellent research partners from abroad -Concentration of resources and widening of participation in international, interdisciplinary and inter-sectoral projects through bridging Cohesion and innovation funds with H2020 and other EU funded opportunities -Massive dissemination to promote bio-economy and exploit the existing potential in region.";2721662,5;2449496;H2020-WIDESPREAD-2014-2;/CSA;INSTYTUT UPRAWY NAWOZENIA I GLEBOZNAWSTWA, PANSTWOWY INSTYTUT BADAWCZY;PL;;;;1;0;0;3;0;0 202774;702296;MIGROPOLIS;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Renaissance Migropolis: Mobility, Migration and the Politics of Reception in Venice (ca. 1450-1650);2016-10-01;2018-09-30;;"This project aims to provide an invaluable new perspective on the motives, practices and consequences of migration in European history, by examining one of the most dynamic and cosmopolitan of past urban societies: Renaissance Venice (ca. 1450-1650). It will do this by investigating quotidian practices of mobility and in particular the early, liminal phases of migrant journeys through the city, producing a closely-focused study of spaces of first arrival for mobile people in Venice, such as inns, lodging houses, ferry stations and quays. Employing an innovative, interdisciplinary methodology, the project will map these key entry-points where new arrivals first sought shelter, food, work, information and human connection, revealing them as crucial sites of interaction and negotiation between newcomers and the local community and as hubs of the authorities’ developing systems of migrant surveillance and identification. Dissemination of the research via a monograph, journal articles and conference papers, as well as planned Public Engagement activities including a digital map of sites of arrival, a radio documentary pitch and an interdisciplinary workshop, will provide a vital historical perspective to contemporary debates on European migration. More broadly, the research will foster knowledge and expertise on vital themes of European history such as the development of policies of reception and hospitality, integration and assimilation, border control and identification, and their impact on states and urban centres as well as on local communities and migrants themselves. The Fellowship will also offer the candidate exceptional knowledge transfer, training and career development opportunities; in particular, her research will be enriched by participation, at the host institution, in an unrivaled concentration of expertise on comparative, transnational and interdisciplinary dimensions of European migration.";172477,2;172477,2;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;EUROPEAN UNIVERSITY INSTITUTE;IT;;;;1;0;0;3;0;0 221487;835682;EMUSIG;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Emotional Musical Signals;2019-05-01;2021-04-30;;The emotional power of music is a force we reckon with on a daily basis. Bubbly music in advertisements entices us to buy products. Tranquil music in medical waiting rooms evokes calm and diffuses anxiety. In spite of its extensive influence, there are still many open questions about how music impacts our emotions. One emotion in particular has been largely overlooked in music and emotion research: fear. The lack of research is surprising given the important role fear plays in society. Fear-based mental disorders are the most widespread, negatively impacting the lives of millions worldwide. Fear drives our daily behaviors and thus is used frequently to spread beliefs for political gain. Given its relevance, there are many benefits for deepening our understanding of fear. Music, a powerful emotional influencer, could be the ideal tool for furthering our knowledge of fear. This groundbreaking, interdisciplinary action will unlock the potential of music as a platform for fear research through the combined use of methods from cognitive neuroscience, behavioral psychology, and music theory. Specifically, my research objectives are to create a new multicultural database of scary music excerpts, catalogue cultural and biological musical fear signals, and synthesize the results of this research into a comprehensive report on musical fear signaling. My training in music theory and cognition methods and my expertise in film music make me the ideal person for this action. The interdisciplinary, state-of-the-art research environment at the Cognitive and Affective Neuroscience Laboratory at the University of Zurich is the perfect location for this work. At this pioneering lab in the field of vocal and music perception, I will be trained in cognitive neuroscience methods (fMRI & eye tracking), statistical and programming skills, and in communicating my interdisciplinary work, fostering my development as an independent music cognition scholar capable of leading my own laboratory.;191149,44;191149,44;H2020-MSCA-IF-2018;/MSCA-IF-EF-ST;UNIVERSITAT ZURICH;CH;;;;1;0;0;3;0;0 205548;722561;TEAM;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2016;H2020;Technology Enabled Adolescent Mental Health;2016-11-01;2020-10-31;;"There is no health without mental health. 27% of our population are young, and mental health disorders are our leading cause of disability. 50% of mental disorders emerge by 14 yrs, 75% by 24 yrs and, untreated, triple odds of having a mental health disorder in later life. TEAM’s will build a network of expertise and train a new generation of researchers to deliver more effective, affordable and feasible mental health services for young people. Our interdisciplinary, international, intersectoral network, balanced in skills, experience and perspectives, will train the next generation of researchers to lead Youth Mental Health (YMH) services into the future. Research objectives focus on key challenges in YMH: delivering new technologies to support rapid, large-scale, and early assessment, prevention and treatment.TEAM will also deliver policy directions and guidelines for technology-enabled YMH. 2 themes are covered: how can technology a) increase access, and b) help people to engage more successfully? TEAM will deliver new technology-enabled services that are both accessible and engaging for young people. Our ambitious objectives require individuals with a unique combination of interdisciplinary and intersectoral skills. TEAM ESRs will receive integrated training across three key areas necessary to fully realise the potential of technology-enabled mental health: Mental Healthcare Delivery - the theories and practice of YMH; Computer science - core principles in software engineering and technology infrastructures; Interaction Design - theories and methods including co-designing with young people and active engagement with clinicians, social workers, caregivers (e.g. parents) and teachers. Intersectoral secondments promote interdisciplinary and intersectoral learning and communication, and public engagement and outreach focus on young people, those who play major roles in their lives (e.g. parents and teachers), health care professionals.";3971595,23;3971595,23;H2020-MSCA-ITN-2016;/MSCA-ITN-ETN;UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN;IE;"MEDIZINISCHE UNIVERSITAET WIEN;REGION HOVEDSTADEN;TECHNISCHE UNIVERSITAET WIEN;TELEFONICA INNOVACION ALPHA SL;THE ANNA FREUD CENTRE;TELEFONICA INVESTIGACION Y DESARROLLO SA;DANMARKS TEKNISKE UNIVERSITET;UNIVERSITY OF GLASGOW;REACHOUT IRELAND LTD";"AT;DK;ES;UK;IE";;1;0;0;3;0;0 214839;786698;CYBER-TRUST;SIGNED;H2020-EU.3.7.4.;DS-07-2017;H2020;Advanced Cyber-Threat Intelligence, Detection, and Mitigation Platform for a Trusted Internet of Things;2018-05-01;2021-04-30;;"The CYBER-TRUST project aims to develop an innovative cyber-threat intelligence gathering, detection, and mitigation platform to tackle the grand challenges towards securing the ecosystem of IoT devices. The security problems arising from the flawed design of legacy hardware and embedded devices allows cyber-criminals to easily compromise them and launch large-scale attacks toward critical cyber-infrastructures. The proposed interdisciplinary approach will capture different phases of such emerging attacks, before and after known (even years old) or unknown (zero-day) vulnerabilities have been widely exploited by cyber-criminals to launch the attack. Emphasis is given on building a proactive cyber-threat intelligence gathering and sharing system to prevent the exploitation of zero-day vulnerabilities. This intelligence information will be used to maintain accurate vulnerability profiles of IoT devices, in accordance with data protection, privacy, or other regulations, and optimally alter their attack surface to minimise the damage from cyber-attacks. Novel technologies will be developed, based on distributed ledgers and blockchains, to monitor devices’ integrity state and network behaviour that will considerably increase the detection and response capabilities against targeted and interdisciplinary cyber-attacks. In the case of alleged malicious activity, tools for collecting and storing forensic evidence on a tamper-proof blockchain structure will be delivered, taking into account the specific needs of law enforcement agencies. Privacy-preserving network monitoring and advanced virtual reality-based visualisation techniques will be employed for quickly detecting botnets, DDoS attacks and other incidents. Relying on interdisciplinary research, an intelligent autonomous cyber-defence framework will be built for providing intelligent ways of isolating the devices under an attacker’s control (or infected) and effectively responding to and mitigating large-scale attacks.";2996182,5;2996182,5;H2020-DS-SC7-2017;/RIA;KENTRO MELETON ASFALEIAS;EL;"SCORECHAIN SA;MATHEMA SRL;VRIJE UNIVERSITEIT BRUSSEL;CGI NEDERLAND BV;ADITESS ADVANCED INTEGRATED TECHNOLOGY SOLUTIONS & SERVICES LTD;UNIVERSITY OF PLYMOUTH;MTN CYPRUS LIMITED;UNIVERSITY OF PELOPONNESE";"LU;IT;BE;NL;CY;UK;EL";;1;0;0;3;0;0 198460;648535;ArtEmpire;SIGNED;H2020-EU.1.1.;ERC-CoG-2014;H2020;An ARTery of EMPIRE. Conquest, Commerce, Crisis, Culture and the Panamanian Junction (1513-1671);2016-01-01;2020-12-31;;"European incursions onto the narrow isthmian pass that divided and connected the Atlantic and Pacific oceans made it a strategic node of the Spanish Empire and a crucial site for early modern globalization. On the front lines of the convergence of four continents, Old Panama offers an unusual opportunity for examining the diverse, often asymmetrical impacts of cultural and commercial contacts. The role of Italian, Portuguese, British, Dutch, and French interests in the area, as well as an influx of African slaves and Asian merchandise, have left a unique material legacy that requires an integrated, interdisciplinary approach to its varied sources. Bones, teeth and artifacts on this artery of Empire offer the possibility of new insights into the cultural and biological impact of early globalization. They also invite an interdisciplinary approach to different groups’ tactics for survival, including possible dietary changes, and the pursuit of profit. Such strategies may have led the diverse peoples inhabiting this junction, from indigenous allies to African and Asian bandits to European corsairs, to develop and to favor local production and Pacific trade networks at the expense of commerce with the metropolis. This project applies historical, archaeological and archaeometric methodologies to evidence of encounters between peoples and goods from Europe, America, Africa and Asia that took place on the Isthmus of Panama during the sixteenth and seventeenth centuries. Forging an interdisciplinary approach to early globalization, it challenges both Euro-centric and Hispano-phobic interpretations of the impact of the conquest of America, traditionally seen as a demographic catastrophe that reached its nadir in the so-called seventeenth-century crisis. Rather than applying quantitative methods to incomplete source material, researchers will adopt a contextualized, inter-disciplinary, qualitative approach to diverse agents involved in cultural and commercial exchange.";1998875;1998875;ERC-2014-CoG;/ERC-COG;UNIVERSIDAD PABLO DE OLAVIDE;ES;"CURT-ENGELHORN ZENTRUM ARCHAOMETRIEGGMBH-CEZA;UNIVERSITA DEGLI STUDI DI PAVIA;FUNDACION UNIVERSIDAD DEL NORTE";"DE;IT;CO";;1;0;0;3;0;0 212859;765921;IoT4Win;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2017;H2020;Internet of Thing for Smart Water Innovative Networks;2018-03-01;2022-02-28;;"The IoT4Win will establish a European Industrial Doctorates (EID) training program and extend the traditional academic research training setting, equipping researchers with right combination of research-related and transferable competences, joint research training programme combines an interdisciplinary expertise of European research group, industry partners and user organisations, bring together all required knowledge, skills, and stakeholders to offer a comprehensive set of transferable skills and a training programme on ICT, data science and water engineering, including industry practice and longer-term benefit in further industrial partner collaborations and further knowledge transfer. IoT4Win will respond to well defined and interdisciplinary scientific questions and challenges on IoTs for Smart Water Network (SWN) technological area cooperating to recruit 3 ESRs to undertake research in the context of a joint research training on concepts and methodologies of IoT enabled SWN towards the PhD. IoT4Win designs 3 individual and personalised research projects covering the core SWN research areas, i.e. smart sensing and trusted communication within energy limited heterogeneous devices in IoT enabled urban water environment; dynamic sensor web and interoperable open platform with Integrated Knowledge Management for smart water networks; data security and intelligence in IoT enabled SWN. The interdisciplinary collaborations and cross industrial interactions between ICT and water sector, will expose researchers to the academic, non-academic sectors. By combining three projects, an interoperable, secure and intelligent underlying technology leading to an open platform for IoT enabled SWN applications will be developed. This platform will then be applied to and evaluated in the real water scenarios with our end user industrial partner, leading to a specialised technology platform for SWN and a best-practice smart water network demonstrator.";761644,44;761644,44;H2020-MSCA-ITN-2017;/MSCA-ITN-EID;BIRMINGHAM CITY UNIVERSITY;UK;SINGULARLOGIC ROMANIA COMPUTER APPLICATIONS SRL;RO;;1;0;0;3;0;0 211610;765515;ENSYSTRA;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2017;H2020;Energy Systems in Transition;2017-10-01;2021-09-30;;"To facilitate the necessary energy transition, there is an urgent need for highly trained professionals with the scientific knowledge and professional skills to analyse, understand and design relevant (new) energy systems and governance in different sectors and administration. The proposed project Energy Systems in Transition (ENSYSTRA) aims to train 15 ESRs in this field. The objectives of ENSYSTRA are 1) to develop state-of-the-art science of energy systems transition, scenario analysis and energy modelling tools with emphasis on interdisciplinary model collaboration, 2) to provide ESRs with interdisciplinary, inter-sectoral and applied perspectives on the energy transition, 3) to provide new skills and competences for interdisciplinary analysis, 3) to establish collaboration between key universities and their networks, 4) to create and increase linkages between different academic disciplines, applied research, industry and the public sector, 5) develop links and synergies between relevant scientific arenas, and 6) to contribute to accessible energy science based on open source work environments. By focussing on a prominent ‘’living lab’’ of the energy transition, the North Sea region, the project will bring together a strong network and analytical capacity to understand energy system & scenario modeling; new energy technologies & infrastructures; actor behavior & interactions; and policy & market design, linking the regional to the international scale. Through a carefully designed training programme, ESRs are trained in both scientific and transferable skills with ample opportunity to collaborate between different projects and partners. The total effort will result in major progress in the field of energy system analysis and transition modelling. By the combined use and improvement of a range of modelling tools and methods, the project will deliver integral insights in energy transition pathways, policy implications and options for the North Sea region.";4067521,56;4067521,56;H2020-MSCA-ITN-2017;/MSCA-ITN-ETN;RIJKSUNIVERSITEIT GRONINGEN;NL;"EUROPA-UNIVERSITAT FLENSBURG;UNIVERSITETET I STAVANGER;AALBORG UNIVERSITET;THE UNIVERSITY OF EDINBURGH;CHALMERS TEKNISKA HOEGSKOLA AB";"DE;NO;DK;UK;SE";;1;0;0;3;0;0 219233;823803;DisTerrMem;SIGNED;H2020-EU.1.3.3.;MSCA-RISE-2018;H2020;Memory Across Borders: Dealing with the Legacy of Disputed Territories;2019-02-01;2022-01-31;;"DisTerrMem is an integrated programme of training and mobility opportunities for researchers and non-academic partners, who will co-create an innovative transnational, interdisciplinary and multi-level approach to the pressing problem of managing competing memories of disputed territories across borders. Taking an interdisciplinary collaborative approach, the planned secondments and training will share and extend interdisciplinary knowledge. Methods to share knowledge will include cross-disciplinary seminar series, the co-production of literature reviews and a shared methodological and theoretical framework, the organisation of internal conferences and summer schools, the production of jointly-authored academic publications, as well as an international conference. These activities will facilitate the co-creation of a new theoretical and methodological approach to a significant problem. Dealing with competing and often antagonistic memories of disputed territory remains a pressing challenge not just within the EU, but globally. However, the solution to such tensions is not necessarily the formulation of a ‘shared’ memory of such territories, which in any case may prove difficult to achieve. As a recent report of the European Parliament (2013: 5-6) notes, while historical memory is already disputed at the national level, beyond the national frame ‘the perception of the past proves all the more heterogeneous and problems for having a collective memory or even defining common historical landmarks are multiplied.’ Researchers on this project will receive the training necessary for them to address the challenge of managing competing memories of disputed territories in three key regions (Europe, South Asia and the South Caucasus), producing insights into best practice that will be useful to policymakers at the national and supranational level, to civil society groups and to cultural practitioners.";533600;533600;H2020-MSCA-RISE-2018;/MSCA-RISE;UNIVERSITY OF BATH;UK;"UNIWERSYTET WARSZAWSKI;FUNDACJA POGRANICZE;EDUCATIONAL AND CULTURAL BRIDGES;NATIONAL ACADEMY OF SCIENCES OF THE REPUBLIC OF ARMENIA";"PL;AM";;1;0;0;3;0;0 217790;818464;UNIGHTED;SIGNED;H2020-EU.1.3.5.;MSCA-NIGHT-2018;H2020;United Europe – United Science – United Culture – United Night;2018-06-01;2019-12-31;;"Researchers’ Night in Poznan is back! UNIGHTED is “United Europe – United Science – United Culture – United Night”! The project is a unique undertaking of science united, an opportunity to see in action scientists from different fields working together. Discover the interdisciplinary character of science, check out how various areas of science complement each other to make our life better. Take part in an innovative interdisciplinary event “Where sciences converge” and observe how scientists in various areas of science collaborate for the common good. Have a glance into research laboratories and see up close the nature of researchers’ work; observe how robots help in telemedicine, enter FutureSmartSpace and see how new technologies influence interpersonal relationships; carry out experiments in a biotechnology laboratory; uncover the mysteries of meteorites, join in dance and sports. Find out that people of science are ordinary people and their work is simply fascinating. In the context of “United Europe – United Science – United Culture” learn how common European heritage has been influencing a variety of sciences, and how researchers have been working for the common good of entire Europe. And all that thanks to science presented in a fun and straightforward way (edutainment). The UNIGHTED project contains a continuation of projects from previous 11 editions as well as many new ideas. Year after year more participants are attracted to Researchers’ Night as new generations grow up, interested in science and people of science. Every year new venues are opened and programmes are enlarged in order to accept all those interested. This year’s project aims to build on the previous ones and to shed light on novel aspects of science: its interdisciplinary character, common research work for Europe and Europeans. Researchers’ Night both in 2018 and 2019 shall be a great celebration of science, a family fun as well as an alternative to traditional Friday night activities.";150500;143500;H2020-MSCA-NIGHT-2018;/CSA;POLITECHNIKA POZNANSKA;PL;"UNIWERSYTET IM. ADAMA MICKIEWICZA W POZNANIU;UNIWERSYTET PRZYRODNICZY W POZNANIU*;INSTYTUT CHEMII BIOORGANICZNEJ POLSKIEJ AKADEMII NAUK;AKADEMIA WYCHOWANIA FIZYCZNEGO IM EUGENIUSZA PIASECKIEGO;UNIWERSYTET EKONOMICZNY W POZNANIU";PL;;1;0;0;3;0;0 211630;764785;FORA;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2017;H2020;Fog Computing for Robotics and Industrial Automation;2017-10-01;2021-09-30;;"We are at the beginning of a new industrial revolution (Industry 4.0): disruptive technologies such as cyber-physical systems, machine-to-machine communication, Big Data and machine learning, and human-robot collaboration will transform the manufacturing and industrial automation sectors. However, Industry 4.0 will only become a reality through the convergence of Operational and Information Technologies (OT & IT). The European Parliament, says that “a very wide range of skills is required for [Industry 4.0] implementation. […] the convergence of IT, manufacturing, automation technology and software requires the development of a fundamentally new approach to training IT experts.” The FORA interdisciplinary, international, intersectoral network will train the next generation of researchers to lead this convergence and cross the IT-OT gap. The convergence will be achieved through the new concept of Fog Computing, which is a logical extension from Cloud Computing towards the edge of the network (where machines are located), enabling applications that demand guarantees in safety, security, and real-time behavior. Research objectives focus on: a reference system architecture for Fog Computing; resource management mechanisms and middleware for deploying mixed-criticality applications in the Fog; safety and security assurance; service-oriented application modeling and real-time machine learning. Our ambitious objectives require individuals with a unique combination of interdisciplinary and intersectoral skills. Thus, FORA’s 15 ESRs will receive integrated training across key areas (computer science, electrical engineering, control engineering, industrial automation, applied mathematics and data science) necessary to fully realize the potential of Fog Computing for Industry 4.0 and will move between academic and industrial environments to promote interdisciplinary and intersectoral learning.";4000793,4;4000793,4;H2020-MSCA-ITN-2017;/MSCA-ITN-ETN;DANMARKS TEKNISKE UNIVERSITET;DK;"TECHNISCHE UNIVERSITAET WIEN;ABB AB;SYSGO AG;TECHNISCHE UNIVERSITAET KAISERSLAUTERN;TTTECH COMPUTERTECHNIK AG;MAELARDALENS HOEGSKOLA";"AT;SE;DE";;1;0;0;3;0;0 209854;754507;SPARK;SIGNED;H2020-EU.1.3.4.;MSCA-COFUND-2016;H2020;Supporting Pioneer doctoral Researchers through 3i Knowledge partnerships;2017-05-01;2022-04-30;;"The SPaRK Programme is driven by the need to develop future leaders whose skills combine disciplinary excellence with a capacity for interdisciplinary and intersectoral working that creates genuinely disruptive thinkers. SPaRK recognises that genuinely game-changing intersectoral, international and interdisciplinary collaboration does not happen simply by making available opportunities for mobility, placements, or input from other disciplines. It is therefore designed to offer an innovative model of professional and scientific development that is proactively training researchers to be able to maximise the potential of these 3i partnerships. Only by rethinking our current, competence-based skills agenda in ways that embrace a model based on intellectual flexibility and creativity can we prepare the leaders who will be equipped to respond to constantly shifting global challenges. The SPaRK programme thus proposes the integration of disciplinary excellence with a meaningful reflection on the possibilities both of interdisciplinarity and of mobility across cultural, linguistic, professional and epistemological borders. QUB is ideally placed to host this programme. It is the UK leader in Knowledge Transfer Partnerships and has an outstanding reputation for nurturing research with societal impact across the cultural, commercial and scientific economies. In addition, Queen’s enjoys a significant track record in attracting funding for cohort-based doctoral training programmes (ITNs, UK Research Councils), and as testimony to its record of excellence in, and commitment to, enhanced doctoral training, the university has recently invested the equivalent of 7m euros in a new Graduate School (opened in April 2015), of which the PI for this application is Dean. The Graduate School will host the SPaRK cohort, providing world-class facilities as well as an intellectual hub for 3i training, debate and dialogue.";3139200;1569600;H2020-MSCA-COFUND-2016;/MSCA-COFUND-DP;THE QUEEN'S UNIVERSITY OF BELFAST;UK;;;;1;0;0;3;0;0 203182;713600;artes EUmanities;SIGNED;H2020-EU.1.3.4.;MSCA-COFUND-2015-DP;H2020;a.r.t.e.s. EUmanities - European Graduate School for the Humanities Cologne;2017-04-01;2022-03-31;;"artes EUmanities offers a doctoral programme (DP) with a mandatory mobility phase, as part of the established artes Graduate School for the Humanities Cologne (AGSHC). Designed around the needs of each individual Early Stage Researcher (ESR) in the Humanities, it will provide places for up to 10 ESRs every year for 3 years. EUmanities relies on a structured but flexible bottom-up approach, providing an interdisciplinary DP for the entire Humanities that supports ESRs to design their own individual research and career development. Thanks to a wide-spread network of regional, European and global networks of excellent research, academic and intersectoral partner organisations, they will learn to work discerningly and decisively, think and engage beyond disciplinary, national and sectoral boundaries. artes EUmanities will be implemented in accordance with the targets of the Horizon 2020 objectives regarding excellent research, stable working conditions and the implementation of the triple “i” dimension through: 1) two international mobility options (a global outgoing phase of 18 months – artes global, or an inner-European outgoing phase of at least 12 months - artes EU); 2) extensive guidance by an interdisciplinary and international team of 3 supervisors and within multidisciplinary Graduate Classes; 3) support for a prompt transition into subsequent career stages thanks to the career development programme and a close cooperation with various intersectoral partners. artes EUmanities will guarantee a sustainable impact on the whole institutional structure of the ASGHC, transforming it into an excellent European graduate school with a strong international outreach and a distinctive interdisciplinary approach. It will offer Europe a leading model for innovative DPs and research training that will empower ESRs in the Humanities to become aware of their own potential in mediating sensitive and complex issues to make them accessible to different addressees.";4708800;2354400;H2020-MSCA-COFUND-2015;/MSCA-COFUND-DP;UNIVERSITAET ZU KOELN;DE;;;;1;0;0;3;0;0 216345;801604;DTA3;SIGNED;H2020-EU.1.3.4.;MSCA-COFUND-2017;H2020;Extended University Alliance Doctoral Training Alliance in Energy, Applied Biosciences for Health and Social Policy DTA3;2018-06-01;2023-05-31;;"The DTA3 will develop 83 early-stage researchers (ESRs) as internationally connected, independent researchers with interdisciplinary and inter-sectoral skills and experience, ready for industrial employment in the European and UK priority challenge areas of healthcare, clean energy and social policy. Building on existing individual doctoral programmes, DTA3 is delivered through a consortium of 12 universities across England and Wales, with associate partners in Europe and Australia. COFUND will support the full integration of three existing individual programmes of training in applied biosciences for health, energy and social policy. This will increase the employability gains for graduate ESRs, who will benefit both from deep subject expertise and a broad understanding of the global challenges in these three key sectors. This responds to identified employer needs and will enable ESRs to transfer quickly and easily into a range of industry roles across the globe after their study. DTA3 provides access to expertise and research equipment across 12 institutions and an additional layer of cross-disciplinary training opportunities. ESRs will graduate from the programme with a solid grasp of the context of their skills and knowledge in the global labour market, and an international professional community of peers and employer networks. Thus, the over-arching ambition of DTA 3 is the development of a mobile, interdisciplinary and international ESR community able to solve grand challenges by working across healthcare, energy and social policy sectors. It seeks to build a cohort with broad connections to professional networks, industry and commerce across these three key sectors. Core objectives have been identified: - Development of a mobile, interdisciplinary & international ESR community able to solve grand challenges - Focus on communication & translation of applied research - Involve supervisors as an integral part of the programme";13027680;6513840;H2020-MSCA-COFUND-2017;/MSCA-COFUND-DP;UNIVERSITY ALLIANCE;UK;;;;1;0;0;3;0;0 214421;789524;CO-SUSTAIN;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Collaborative Sustainable Innovation: co-designing governance approaches for a sustainable and innovative small-scale fishing industry in the Irish islands;2018-10-01;2020-09-30;;The aim of this Fellowship is to provide Dr Ruth Brennan with advanced interdisciplinary training and new skills and experience in order to enhance her innovative and creative potential, increase her knowledge base, expand her career possibilities and enable her to reach professional maturity commensurate with a leading researcher in Ireland and internationally. The researcher will be based at the Centre for Environmental Humanities (CEH), School of Histories and Humanities, Trinity College Dublin, working under the supervision of Professor Poul Holm. Research training will be implemented through an interdisciplinary project to investigate whether, and how, the Irish small-scale fishing industry can develop innovative fishing models that promote good governance, foster marine stewardship and contribute to climate change goals while meeting the need of fisheries-dependent coastal communities to flourish. The specific aim of the project is to co-design and test innovative governance approaches that address the needs of fisheries-dependent island communities and meet national and European marine planning and conservation objectives. The researcher is trained in marine social science, environmental governance and law. CEH expertise is focused on positioning the Environmental Humanities (including social science) as having a crucial role to play in understanding human motivation and behaviour in the face of the challenges of global environmental change. The researcher’s continued exposure to the CEH will provide her with advanced interdisciplinary training necessary for advancement of her career and project success. The resources of the host institution will facilitate the development of an Irish and international academic network, as well as career mentoring, and will firmly establish the researcher as a science-policy expert in addressing the societal challenge of sustainable and socially inclusive marine resource management while conserving the marine environment.;175866;175866;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN;IE;;;;1;0;0;3;0;0 214571;794484;ENAMARE;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Enactive model of aesthetic perception through rhythm and entrainment;2018-06-01;2020-05-31;;"ENAMARE is an innovative project that will study the functionality of the aesthetic constituent of general perception through the use of an enactive approach and conceptual tools from the dynamic systems theory. This will be done through the elaboration of a interdisciplinary model based on interactional loops between environmental and bodily rhythms mediated by the phenomenon of entrainment and their implications on processes of sense-making and engagement. This project will address general perception, thus, as a temporally extended process arising from dynamic interactions between agent and environment with an inherent and vital aesthetic component involved in our constant reappraisal of the world and ourselves. In coherence with enactivism, the theoretical framework will be grounded on philosophy but will integrate research results and theory from biology and neurosciences as well. It is a particularly timely moment to conduct ENAMARE. Despite relevant researchers asking for projects addressing this topic and interdisciplinary research focused on different aspects of cognition, there has yet to be a thorough and comprehensive research on aesthetic influence over everyday perception. It would lead to a better understanding on the reciprocal effect and influence between environment and agents, and it would also enhance European research in fields as diverse as urbanism, education or artificial intelligence. My background, which covers biology, neuroscience and humanities, puts me in a unique position to develop a project that will grant me methodological expertise and theoretical knowledge. This will help me develop into a solid interdisciplinary researcher by successfully integrating all sides of my previous academic formation.";168277,2;168277,2;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;UNIVERSITA CA' FOSCARI VENEZIA;IT;;;;1;0;0;3;0;0 214895;787671;MarHIST;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Historical dynamics of coastal and marine ecosystem services.;2018-10-01;2020-09-30;;"This project addresses the globally important problem of how we sustain coastal and marine ecosystem services. Ecosystem services, the benefits humans gain from ecosystems, are fundamental to societal well-being, but marine ecosystem services research lags behind its terrestrial counterpart, while historical dynamics are frequently overlooked. Without understanding long-term dynamics in marine ecosystem services, we risk missing declines in services that may affect societal well-being. This includes our understanding of interactions among services, the role of societal feedbacks on service provision and prediction of social-ecological tipping points. This project aims to interrogate historical data to reveal the dynamics of coastal marine ecosystem services over decadal to centennial timescales. By integrating interdisciplinary sources and methodologies from archaeology, history and ecology disciplines, the project will examine dynamics and social-ecological feedbacks in provisioning, regulating and cultural coastal marine ecosystem services. Under the mentorship of Profs Godley and Bateman, and by collaborating with University of Exeter researchers from a range of disciplinary backgrounds, I will be able to expand my research horizons and learn new interdisciplinary skills. This will not only enable me to strengthen my CV, placing me in a strong position to achieve my career goals of becoming a leading researcher within the European community, it will contribute new interdisciplinary research to the ecosystem services and ecology fields, thus improving our understanding of the links between marine ecosystems and societal well-being, a critical knowledge gap of global relevance. These findings will also produce baseline data and methods that will be readily translatable to policy (such as the European Commission’s Blue Growth Strategy) and able to inform sustainable resource management goals, with benefits for both society and the environment.";195454,8;195454,8;H2020-MSCA-IF-2017;/MSCA-IF-EF-RI;THE UNIVERSITY OF EXETER;UK;;;;1;0;0;3;0;0 211316;742204;ROCKY;SIGNED;H2020-EU.1.1.;ERC-2016-ADG;H2020;Forests and Trees: the Formal Semantics of Collective Categorization;2017-11-01;2022-10-31;;"Languages have various ways of referring to collections like families, herds and forests. The grammatical properties of collective expressions critically determine how we understand them. The sentences “this forest is old” and “these trees are old” categorize an arboreal collection using a concept (“old”), while conveying different meanings. This semantic difference correlates with the difference in grammatical number between the sentences: singular vs. plural. Such effects of collective categorization in language are crucial for understanding the connections between grammar and the mind, as well as for artificial intelligence. However, currently little is known about the mechanisms underlying our linguistic ability to conceptualize collections. This project aims to develop a novel linguistic theory of this ability, applied to a wide range of empirical phenomena and interdisciplinary challenges in computational semantics and comparative linguistics, benefiting from the recent synergy between linguistics and the psychology of concepts. The idea is that when classifying a collection, speakers rely on two inferential principles with mental concepts: (i) geometric inferences: a forest is considered “far away” if all of its trees are far; (ii) symmetric inferences: two trees are “similar” if each of them is similar to the other. The leading hypothesis is that uniform interactions between these inferential principles and the grammar of collective expressions account for collective categorization in language. This hypothesis is explored in three work packages, each of which develops the semantic theory and evaluates it on a different interdisciplinary domain: human interaction with geographic information systems, behavioral linguistic experiments, and comparative linguistics. Together, the three components of the project are expected to lead to a theoretical breakthrough in semantic theory and to enrich its interdisciplinary connections with neighboring disciplines.";2494278,75;2494278,75;ERC-2016-ADG;/ERC-ADG;UNIVERSITEIT UTRECHT;NL;CITY UNIVERSITY OF LONDON;UK;;1;0;0;3;0;0 205473;722482;ESSENTIAL;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2016;H2020;Evolving Security SciencE through Networked Technologies, Information policy And Law;2017-01-01;2020-12-31;;"Though security is a field of study capable of diverse applications in daily life, security science is a young discipline requiring larger inter-disciplinary effort. ESSENTIAL seeks to develop security science by addressing two of its main problems: the ad-hoc approach to security research and the growing complexity of the security environment. To do so, ESSENTIAL has set itself two main goals: a) to train inter-disciplinary security experts and professionals, to tackle security threats in a systematic manner and b) to increase societal resilience and security by addressing in an interdisciplinary manner 15 research topics, each associated with long-standing problems in the field of security science ranging from modeling security perception and democratizing intelligence to improving security and privacy in data ecosystems. ESSENTIAL will be the first programme of its kind that aims to jointly educate the next generation of interdisciplinary experts in security science, by uniquely exposing the 15 ESRs to: (1) theoretical knowledge and practical expertise in such areas as: (a) the policing and regulation of information-security technology, and (b) the implementation of policies and legal standards within computing and communication systems; (2) real-world environments in law enforcement, intelligence and industry; (3) strong academic guidance offered by highly qualified supervisors and mentors; (4) high tech research infrastructures; and (5) a diversity of interdisciplinary research events, such as workshops, conferences, summer/winter schools. The ESSENTIAL consortium is built upon long-lasting cooperation relations among leading organizations coming from academia, international and national stakeholders and the private sector, many of whom have over 25 years of experience in contributing directly to national, European and UN technology-related policy making.";3756496,68;3756496,68;H2020-MSCA-ITN-2016;/MSCA-ITN-EJD;RIJKSUNIVERSITEIT GRONINGEN;NL;"Edith Cowan University;CONSIGLIO NAZIONALE DELLE RICERCHE;UNIVERSITA TA MALTA;NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU;ACADEMIA NATIONALA DE INFORMATII MIHAI VITEAZUL";"AU;IT;MT;NO;RO";;1;0;0;3;0;0 213944;785964;CogLit;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;"Literature as a Cognitive Object; Cognitive infrastructure and human cultural transmission";2018-10-18;2020-10-17;;"Interdisciplinary research between literary and art study and empirical disciplines such as linguistics and cognitive science lacks genuine reciprocity: scholars of literature and art have drawn extensively on linguistics and cognitive science, but literary and art-philosophical discourse has had little impact in these empirical domains. This project argues for genuine, two-way interdisciplinary practices in literary and art study and aims to show how research in empirical domains can not only influence but also be influenced by the investigation of literary and other art forms. The first objective of the project will focus on mental causation in order to refine my suggestion that what distinguishes works of literature and art from other objects is their cognitive aetiology: drawing on Relevance Theory, I will argue that artworks and literary texts are causally related to an art-specific type of relevance-yielding creative mental state, that I term an artistic thought state. The 2nd objective will focus on intended effects: it will take as starting point the relevance-theoretic notion of a worthwhile effect in order to introduce a new, neurologically real type of effects (positive perceptual effects) that make both artworks (e.g. literary texts) and artistic thought states relevant to individual minds. The discussion will have implications for hypotheses in various empirical domains. The IF will, among other things, result in a monograph (‘Literature as a Cognitive Object’), which will make one of the first systematic and empirically tractable proposals in the 21st century on the essence of literature and art and provide a concrete example of how genuine interdisciplinary practices in the Arts and Humanities can directly influence theory formation in scientific domains. Innovative public engagement will be a central feature of this project through a non-academic secondment at the ONCA Arts Centre and collaboration with the UK Centre for Contemporary Poetry.";183454,8;183454,8;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;UNIVERSITY OF BRIGHTON;UK;;;;1;0;0;3;0;0 197243;641458;MELGEN;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2014-ETN;H2020;MELanoma GENetics - understanding and biomarking the genetic and immunological determinants of melanoma survival;2015-06-01;2019-12-31;;"MELGEN (MELanoma GENetics) – understanding and biomarking the genetic and immunological determinants of melanoma survival The MELGEN European Training Network (ETN) will create an environment for long-term, collaborative, inter-sectorial cancer genetics research with the ultimate aim of improving precision (personalised) medicine. In a 2012 report the European Science Foundation identified the importance of precision medicine and recommended that there should be 1) provision of comprehensive, accessible and interoperable datasets 2) improved models and decision-making processes, 3) interdisciplinary, public-private partnerships and translational research, and 4) dedicated funding including access to core technology and frameworks for education and training of professionals. This application addresses all four recommendations and applies them to melanoma. Considerable, but insufficient, progress has been made in understanding the genetic changes within melanomas that drive tumour progression, and how those drivers can be targeted to treat melanoma. Melanoma is also an especially immunogenic cancer and much more needs to be understood of how melanomas suppress host immunological responses. Understanding what controls immunity in melanoma will be potentially applicable to other cancers. Finally, we need prognostic and predictive biomarkers for selection of precision therapy. This ETN will recruit 15 early stage researchers (ESRs) to address these issues. It will bring together leaders in clinical research, genomics, statistics, bioinformatics, and the biotech industry to exploit the new genomic tools and tumour immunology. MELGEN’s commercial partners are developing immunological tests (ImmunID), bioinformatics (Eagle Genomics), commercial genomics (ServiceXS) and digital design/communications (Digitronix) and they will underpin an innovative, interdisciplinary training programme for the next generation of melanoma researchers.";3988365,84;3988365,84;H2020-MSCA-ITN-2014;/MSCA-ITN-ETN;UNIVERSITY OF LEEDS;UK;"ACADEMISCH ZIEKENHUIS LEIDEN;LUNDS UNIVERSITET;GENOME RESEARCH LIMITED;OSLO UNIVERSITETSSYKEHUS HF;UNIVERSITAETSKLINIKUM ESSEN";"NL;SE;UK;NO;DE";;1;0;0;2;0;0 196973;665385;ISTScholar;SIGNED;H2020-EU.1.3.4.;MSCA-COFUND-2014-DP;H2020;International IST Doctoral Program;2015-10-01;2020-09-30;;"The Institute of Science and Technology Austria (IST Austria) is an English language PhD-granting research institute with focus on basic research in the natural and mathematical sciences. ISTScholar offers PhD training in biology, neuroscience, computer science, mathematics, physics and relevant interdisciplinary areas. The program is divided into two distinct phases: Phase 1 is dedicated to course work and rotations. The curriculum is designed to provide a foundation both broad and deep enough to support thesis research across a wide spectrum of cutting-edge research problems. Students have to fulfill a breadth requirement by taking courses outside their own field. Throughout the courses, interdisciplinary approaches will be encouraged through the formation of mixed teams of students. The translation between vocabularies in different disciplines will be emphasized. Students will not be directly affiliated to any research group, but will be supported through a mentor during the first phase. This uncommitted period offers the student the opportunity to work closely with several professors and make an informed choice about his or her future career path. Phase 2 is the period in which the student will primarily work on completing a thesis project. The scientific training will be accompanied by the Career Development Program. Workshop topics include science communication, career planning, time and self-management, and interpersonal skills. ISTScholar therefore offers courses in teaching didactics and there is a teaching requirement for all students. Intersectoral exposure will be guaranteed through the ISTInnovation program with workshops and talks to help translate research findings into innovations. The aim of ISTScholar is to educate a new generation of researchers who are able to approach scientific questions from different angles and are fluent in the languages of both the experimental sciences and analytical sciences.";8789760;4394880;H2020-MSCA-COFUND-2014;/MSCA-COFUND-DP;INSTITUTE OF SCIENCE AND TECHNOLOGYAUSTRIA;AT;;;;1;0;0;2;0;0 222092;838904;MaritimeImagination;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Maritime Imagination: A Cultural Oceanography of The Netherlands;2019-09-01;2022-08-31;;'In 1609, Dutch jurist Hugo Grotius, commissioned by the VOC, published Mare Liberum. The book argued for a juridical distinction between land-based sovereignties and the 'free sea,' heralding a new maritime imagination and international legal order that still persists today. Grotius is not just an exemplary figure for early deliberations on maritime worlds, his work carries particular resonance for Dutch articulations of empire and colonialism rooted in oceanic spaces that have shaped its historical and contemporary position in a global context. Although historians agree that The Netherlands was more interested in commercial maritime trade than European settlement, accounts of Dutch empire and colonialism remain land-based, simply mentioning the ocean as a route between colony and metropole. Maritime Imagination addresses this oversight by developing a cultural oceanography of the Dutch maritime imagination, generating an innovative multi-era and interdisciplinary approach to the study of maritime worlds. Applying an oceanic perspective, I aim to show how a maritime frame -rather than a land-based frame- engenders new ways of theorizing the formation of Dutch empire and colonialism and its impact on the present. Starting from an oceanic framework that crosses existing analytic divides between culture, society, law, economy, and environment, I aim to contribute to the emerging interdisciplinary field of Oceanic Studies. Maritime Imagination researches four interrelated ocean temporalities (17th cent. - present), in which I position Dutch ship voyages as laboratories of colonialism and empire. Visions of the ocean, deeds performed at sea, how they are imagined and their impact are what I call maritime imagination, which can only be illuminated by foregrounding the ocean as a central locus that engenders, shapes and transforms world views, culture, self/other definitions, laws, economy, and ecologies of extraction and sustainability -i.e. through a cultural oceanography.';239817,6;239817,6;H2020-MSCA-IF-2018;/MSCA-IF-GF;UNIVERSITEIT VAN AMSTERDAM;NL;;;;1;0;0;2;0;0 195793;659449;CuPESS;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Catchments under Pressure: Ecosystem Service Solutions;2015-07-01;2017-06-30;;"Catchments are under pressure from impacts on demand and supply and within these constraints water resource managers are challenged to meet multiple and often competing values. The ecosystem services (ES) approach has attracted policy interest as it connects natural capital and the ES flows it supports with human wellbeing. There exists a policy window to translate detailed case study assessment into workable solutions for catchment management in times of change in Europe and beyond. ES research to protect and foster sustainable management of natural resources and ecosystems and the multiple ES they supply fits within the Horizon 2020 programme on Societal Challenges. The U.K. is emerging as a world leader in applying the ES approach to inform and improve natural capital planning and management in land and water resources management practice. The proposed interdisciplinary research would align with these initiatives to examine pragmatic planning solutions adopted in U.K. Water Framework Directive River Basin Districts. The objective of ‘Catchments under Pressure: ES Solutions’ (CuPESS) is to understand how catchment managers are using the ES approach to provide local, adaptive and integrative management solutions in flood prone catchments and what are the opportunities and barriers to wider adoption. This Individual Fellowship will provide opportunity for knowledge exchange, with the fellow returning to Europe and bringing her research expertise on the the ES approach and its use in water resources management in the U.S. and Australia. It will also allow the fellow to build on this research experience in an interdisciplinary research environment, to learn from a new context which will contribute to greater understanding of land-water interconnections, ES innovations and implementation strategies that work in practice. Lessons generated will be of wider relevance for flood risk management in other northern European countries and beyond.";183454,8;183454,8;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;UNIVERSITY OF LEEDS;UK;;;;1;0;0;2;0;0 222389;843152;WMBH;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Waves, mean flows and black holes;2019-11-05;2021-11-04;;"Black holes are among the most fascinating objects of the Universe. They are today at the core of our understanding of gravitation. They provide essential hints towards a theory of quantum gravity. They constitute the main emission source of gravitational waves, which will play a central role in future astrophysics. Black holes are also central in mathematical relativity, and the proof of their stability is still today a challenging problem. In the last decades, several analogies between gravity and fluid mechanics have been developed. This interdisciplinary approach has led to many innovative methods and successful results, which have deepened our understanding of black holes, fluids or superfluids. More recently, such an analogy was used by various experimental groups, which were able to successfully reproduce several key effects of black hole physics using fluid systems. The aim of this project is to develop the mathematical tools to open a new avenue in this interdisciplinary field: the understanding of nonlinear dynamics. In other words, how waves are affected by a background flow or spacetime, and subsequently modify their dynamics. It will focus on three research directions: the analogue of the Hawking effect, superradiant instabilities, and resonances. This project will bring an experienced researcher in analogue models in a strong mathematical physics group, within the Institute of Mathematics of Burgundy (IMB). The objective is to exploit modern mathematics to develop new tools for the joint analysis of black holes and fluids. It will rely on the one hand on mathematical methods of integrable models, and spectral theory of non self-adjoint operators, two fields in which the host group has a traditionally strong expertise, and on the other hand on the knowledge in General Relativity and analogue models of the experienced researcher.";196707,84;196707,84;H2020-MSCA-IF-2018;/MSCA-IF-EF-ST;COMMUNAUTE D' UNIVERSITES ET ETABLISSEMENTS UNIVERSITE BOURGOGNE - FRANCHE - COMTE;FR;;;;1;0;0;2;0;0 222236;840913;WomenWritingSaints;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Women Writing Saints: Proto-feminist Discourses in Religious texts written by Women in Counter-Reformation Italy;2019-08-15;2021-08-14;;"WomenWritingSaints is an interdisciplinary project exploring the religious literature authored by different categories of early modern women writers in post-Tridentine Italy (1563-1700), bringing together literary studies, cultural history, the history of ideas and women’s studies. The sacred writings authored by women writers provides extraordinary grounds for challenging the misapprehension that the Counter-Reformation was an era of overarching repression and censorship. WomenWritingSaints will argue against this premise through an inquiry into the hagiographical production of lay and religious women that will disclose unexpected proto-feminist and political patterns in their writings. By exploring a diverse range of understudied material, including prose writing, hagiographical texts, letters and autobiographical confessional accounts, the fellow, Dr. Stella will revise our understanding of the Counter-Reformation and thoroughly recast the accepted picture of post-Tridentine religious production through a close focus on the key role of female agency. The research, to be based at the Norwegian Institute in Rome, will encompass extensive archival searches in Central Italy (Rome, Florence and Perugia) and will create an open-access database with valuable data on the circulation and ownership of the materials examined. The project will be supervised by Unn Falkeid, Professor of History of Ideas at the University of Oslo, who manages the international interdisciplinary research project, ‘The Legacy of Birgitta of Sweden’ funded by the Research Council of Norway (2018-2021). There is undoubted potential to generate significant valuable research synergy given the overlap in aims and time frame between the two projects. Beyond its scholarly value, the project aims to disseminate important alternative narratives of the history of women, countering oppressive patriarchal discourses which still pervade parts of contemporary Italian and European society.";202158,72;202158,72;H2020-MSCA-IF-2018;/MSCA-IF-EF-ST;UNIVERSITETET I OSLO;NO;;;;1;0;0;2;0;0 222250;841096;BODICON;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;BODIes of CONtact: Identity negotiations and biocultural effects in the Roman colonies of Macedonia, Greece;2020-01-01;2021-12-31;;BODICON examines processes of identity negotiations under colonial regimes by investigating the biocultural effects of conquest and colonisation of the Roman Empire. Representing a new generation of contact studies, the aim is to expand upon traditional elite/non-elite dichotomies or the focus on the health of conquered peoples toward how political transformations are incorporated by the human body of both the colonized and the colonizers. The research focuses on Roman Macedonia (Greece) and explores variable effects of colonisation by analyzing skeletal remains and burial patterns from the colony of Dion, the sacred city and pilgrimage site of ancient Macedonians. To achieve this aim, BODICON adopts for the first time a novel, multifaceted and holistic approach that combines bioarchaeology and current, sophisticated theoretical reflection on culture contact and admixture of populations with cutting-edge interdisciplinary techniques and methodological innovations from other scientific fields (paleodietary reconstruction, biodistance analysis, radiochronology). The Fellowship will offer to the Experienced Researcher (ER) the opportunity to acquire advanced intellectual and technical training and new skills in these fields and reach the research objectives. At the same time, the Fellowship is the timely opportunity for the ER to re-establish her career after a prolonged break and the ideal next step in order to re-enforce her research position. Finally, the creation of interdisciplinary networks as well as the dissemination and communication of the results to the scientific community and the broader public will first, contribute to the global understanding of the formation of modern national identities and second, explore the way historical data are used in contemporary political debates.;187572,48;187572,48;H2020-MSCA-IF-2018;/MSCA-IF-EF-ST;RIJKSUNIVERSITEIT GRONINGEN;NL;;;;1;0;0;2;0;0 222196;840465;E2-CREATE;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;E2-CREATE: Encoding Embodied CreativityVisual arts, performing arts, film, design;2020-04-06;2022-04-05;;Choreography is an art form well-known for combining rigorous physical and mental training with the highest degrees of creativity. However, as dance is the most ephemeral of art forms, this extraordinary embodied creativity has been in danger of disappearing without leaving a significant trace. That was until several leading dance artists began over a decade ago to experiment with digital technology as a means to document their unique approaches to choreography. The result today is an impressive accumulation of interdisciplinary research showing how embodied creativity in dance can be systematically studied and documented, how computer-aided design can effectively communicate the outcomes and how digitised recordings can be processed computationally to reveal new information about choreographic principles, processes and methods. Drawing on these developments in dance digitisation and recent progress in computational arts, the Fellowship will focus on fusing artistic skills in dance with artistic skills in computing. The goal is to achieve a new level of sophisticated creative transfer at the intersection of the two fields by taking advantage of significant advances in the fields of computer vision and machine learning combined with the high-level of expertise the Fellow brings from the field of generative computer art. Generative computer art techniques have until now not been integrated fully into the dance digitisation process, but they have extraordinary potential in combination with machine learning to expand the capability of computational systems to learn from and model existing artistic approaches. The Fellow’s extensive experience of working at the intersection between dance technology and computer art and science means he is extremely well placed to facilitate and achieve this encoding of embodied creativity with lasting impact for mixed machine-human collaboration and interdisciplinary art and science research.;212933,76;212933,76;H2020-MSCA-IF-2018;/MSCA-IF-EF-ST;COVENTRY UNIVERSITY;UK;;;;1;0;0;2;0;0 222205;840550;PRESQUE;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;A predicting platform for designing semiconductor quantum devices;2019-09-01;2021-08-31;;"Quantum technologies and Artificial Intelligence are currently leading R&D and industrial investments of Europe due to their potential to bring large transformations in the digital economy and manufacturing of EU. This project will be based in the research and technology ecosystem of Grenoble, in France, hosted in a Joint Research Unit of Université Grenoble Alpes and CEA. The aim of the project will be to develop a computer-assisted model able to predict the modes of operation of a silicon quantum transistor, giving access to accurate predictions that can decrease the costs involved in designing a quantum circuit. Machine Learning algorithms will be employed for further decreasing the time it takes to optimize the design in a fraction of the original. This project is expected to be an invaluable addition to the enabling technologies for the EU research and innovation and its goals for 'quantum digitization'. The work will be undertaken by Dr. Eleni Chatzikyriakou, with an interdisciplinary background and expertise in the development of computational methods for electron device operation and will be supervised by Dr. Xavier Waintal, that has twenty years of experience in computational studies of various physical phenomena in the quantum regime, and is the leading coordinator of the open source software for quantum transport Kwant. The fellow will be part of a highly specialized group in quantum technologies and will have the opportunity to significantly broaden her knowledge in both quantum technology and Machine Learning through the training and implementation of the action. It is therefore expected that, together with the training in leading and management skills, by the end of the fellowship, she will be in a position to take on leading positions and coordinate interdisciplinary actions by taking advantage of her own and the new networking opportunities that will arise in the fields of (Opto)Electronic Engineering, Computer Science and Physics.";184707,84;184707,84;H2020-MSCA-IF-2018;/MSCA-IF-EF-ST;UNIVERSITE GRENOBLE ALPES;FR;;;;1;0;0;2;0;0 222380;843011;UNBIAS;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;UNravelling BIvAlve Shell chemistry: Advanced Techniques for Accurate Reconstructions of Sub-annual Climate;2019-04-01;2021-03-31;;An important part of climate variability takes place at the sub-annual to decadal scale. However, climate reconstructions mostly focus on long-term trends (thousands to millions of years), while data of past, fast and short-term changes is limited. To calibrate climate models and extend our knowledge of the causes and effects of rapid climate change, archives recording higher resolution climate change are needed. Contrary to sedimentary records, bivalve shells record environmental conditions at a resolution of days to months. Conventional climate proxies in bivalve shells (stable isotopes and trace elements) depend on multiple physiological and environmental parameters, complicating the reconstruction of individual climate parameters. UNBIAS aims to develop new, more accurate tools for absolute reconstructions of climate parameters on a sub-annual scale from bivalve shells. Parameters influencing climate proxies will be disentangled by combining state-of-the-art trace element and microstructure analyses with the new powerful carbonate clumped isotope method, which reconstructs absolute temperature. These techniques are applied directly on cross sections through shells of Arctica islandica, Ostrea edulis and Cerastoderma edule. First, more accurate climate proxies will be developed by applying this interdisciplinary approach on bivalves grown in monitored North Sea environments. After development, these new proxies will first be applied to reconstruct sub-annual climate and environmental change over the past 500 years, recording human impact on North Sea environments. Finally, fossil bivalve shell records from the warm Miocene epoch highlight the effect of global warming on short-term climate variability. UNBIAS provides me with interdisciplinary skills and expertise from specialized institutes in the Benelux and Germany. It will offer me unique chances to gain experience in teaching, professional network and outreach, thus greatly enhancing my career opportunies.;175572,48;175572,48;H2020-MSCA-IF-2018;/MSCA-IF-EF-ST;UNIVERSITEIT UTRECHT;NL;;;;1;0;0;2;0;0 222148;839636;EarlyVertEvo;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Unravelling the scenario of early vertebrate evolution through computational analysis of the fossil record;2019-06-01;2021-05-31;;Debate over the origin of vertebrate bodyplan has occupied biologists and palaeontologists alike for centuries but discussions around this topic have been hindered because living vertebrates are unrepresentative of the ancestral lineages in which the bodyplan was established. Major transitions in early vertebrate evolution have been correlated with a long-term ecological trend from suspension feeding towards increasingly active lifestyles. However, most previous morpho-functional interpretations largely rely on speculation and these ecological explanations of evolutionary events have generally been regarded as untestable as theories. The recent emergence of new virtual techniques in palaeobiology provides for the first time the opportunity to perform rigorous computational and physical examination to test these hypotheses. In this context, the overall aim of my research programme is the joint application of an array of state-of-the-art techniques in palaeobiology to fossil stem-gnathostomes in order to elucidate the ecological scenarios in which the major groups of vertebrates emerged and to shed light onto the underlying selective forces that drove the main evolutionary transitions of the group. For this, the whole morphological diversity and disparity of early vertebrates will be analysed from a functional, temporal and phylogenetic perspective, using Geometric Morphometrics, scanning surface-based technologies, non-destructive X-ray computed tomography, Computational Fluid Dynamic simulations, physical hydrodynamic experiments and several methods for macroevolutionary analysis. This research programme will allow me to establish myself as a world-class independent interdisciplinary researcher by providing a portfolio of high profile publications in international peer-reviewed journals, a world-class suite of interdisciplinary skills, and a world class research programme that will allow me to establish myself as an authority in the field.;212933,76;212933,76;H2020-MSCA-IF-2018;/MSCA-IF-EF-ST;UNIVERSITY OF BRISTOL;UK;;;;1;0;0;2;0;0 222287;841592;Ultra-LightCon-3D;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Ultra-Lightweight Concrete for 3D printing technologies;2019-07-01;2021-06-30;;The construction industry does not follow the same enlightened path as other fields of science and has thus suffered a technology bypass, relying on centuries-old processes and procedures to manage complex modern projects. In conventional concrete construction projects, more than 60% of the total cost is spent on the formwork. One of the technologies which can revolutionize our perception and approach to construction, is 3D printing of concrete. 3D printing, also referred to as Additive Manufacturing (AM), is a technology which builds solid parts via a layer-by-layer process. Since in 3D printing, no formwork is required, and a short project time is required due to continuous work done by the printer, a dramatic reduction in the project cost and improvement of workers’ safety can be achieved. Up to date, much research has been conducted in the field of printing technique, while design of proper insulation of printed walls has gathered little attention. Although, this issue is highly important due to gradually tightening EU regulations. Therefore, proposed project is aiming to fill the gap in knowledge and introduce for the first-time insulating ultra-lightweight concrete (ULWC) material for AM. By proposed interdisciplinary methodology, based on the experimental and numerical methods, in micro- and macro-scales technology, a multi-scale tool enabling to produce advanced 3D printed wall systems. Multi-scale tool will allow to develop 3D models of ULWCs with optimized mechanical and insulating properties. Hence, limited amount of required field and labor works will be necessary, thus further decrement of the final concrete cost and waste production will be achieved. Through the interdisciplinary approach and establishing industrial cooperation, this project will contribute towards development and production of energy saving constructions in accordance with EU Energy Efficiency Strategy.;162806,4;162806,4;H2020-MSCA-IF-2018;/MSCA-IF-EF-ST;TECHNISCHE UNIVERSITAT BERLIN;DE;;;;1;0;0;2;0;0 221916;833125;HIGHWAVE;SIGNED;H2020-EU.1.1.;ERC-2018-ADG;H2020;Breaking of highly energetic waves;2019-09-01;2024-08-31;;"HIGHWAVE is an interdisciplinary project at the frontiers of coastal/ocean engineering, earth system science, statistics and fluid mechanics that will explore fundamental open questions in wave breaking. Why do waves break, how do they dissipate energy and why is this important? A central element of the work builds on recent international developments in the field of wave breaking and wave run-up led by the PI that have provided the first universal criterion for predicting the onset of breaking of water waves in uniform water depths from deep to intermediate. This work has also shown that the run-up of nonlinear waves impinging on a vertical wall can exceed up to 12 times the far-field amplitude of the incoming waves. These results have now opened up the possibility for more accurate operational wave models. They have practical and economic benefits in determining structural loads on ships and coastal/offshore infrastructure, evaluating seabed response to extreme waves, and optimizing operational strategies for maritime and marine renewable energy enterprises. This is a tremendous advance comparable to the introduction of wave prediction during World War II, and the PI aims to be at the forefront of this research effort to take research in wave breaking into fundamentally new directions. The objectives of the project are: (i) to develop an innovative approach to include accurate wave breaking physics into coupled sea state and ocean weather forecasting models; (ii) to obtain improved criteria for the design of ships and coastal/offshore infrastructure; (iii) to quantify erosion by powerful breaking waves, and (iv) to develop new concepts in wave measurement with improved characterization of wave breaking using real-time instrumentation. This highly interdisciplinary project will involve an ambitious and unconventional combination of computational simulation/theory, laboratory experiments, and field measurements of sea waves, closely informed by application needs.";2499946;2499946;ERC-2018-ADG;/ERC-ADG;UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN;IE;;;;1;0;0;2;0;0 221883;831756;THERMES;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;A new generation high temperature phase change microemulsion for latent thermal energy storage in dual loop solar field;2019-09-01;2021-08-31;;New energy storage solutions and innovations play a vital role in fully realising solar energy potentials particularly in large-scale integration into future low-carbon energy systems. For concentrated solar power, one of key challenges lies in low-cost high-performance thermal energy storage. Latent thermal energy storage holds the key to resolving such a challenge and keeping energy supply over periods of inadequate irradiation. THERMES will develop a new generation high-temperature phase change microemulsion both as the latent heat storage material and heat transfer fluid for low temperature solar field of a dual-loop solar field system. The high-temperature phase change microemulsion is characterized by high energy density, enhanced heat transfer performance through the addition of nanoparticles, and cost-effectiveness due to the use of commercial grade paraffin as the latent heat storage medium. By integrating the expertise of the host and Dr. Wenzheng Cui, THERMES will combine cutting-edge experimental, computational and theoretical analysis methods to develop the next generation working medium for latent thermal energy storage in order to meet the key challenge faced by concentrated solar power and fill the research gap of lacking of knowledge on high-temperature properties of phase change microemulsion. This Fellowship will offer Dr. Cui an opportunity through mobility, diverse trainings for acquiring interdisciplinary expertise and transferable skills, and to two-way transfer of knowledge between him and the host. It will position him as an internationally-leading interdisciplinary academic in the research area of latent thermal energy storage for concentrated solar power. THERMES will aggrandize commercialisation of utility-scale concentrated solar power, provide adaptability and support solar energy integration in the energy system. Therefore it is in line with EU’s Energy Strategy and Energy Union for secure, competitive, and sustainable energy.;224933,76;224933,76;H2020-MSCA-IF-2018;/MSCA-IF-EF-ST;THE UNIVERSITY OF BIRMINGHAM;UK;;;;1;0;0;2;0;0 222027;837857;LawLove;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;The origins of the legal protection of heritage. Legislation on the safeguard of monuments and artworks issued in 15th- to 18th-century Europe.;2019-07-01;2022-06-30;;"LAWLOVE proposes an analysis of the laws on the protection of artworks and monuments that were issued in the European countries between early 1400s and late 1700s. The objective is to develop a comparative analysis of legislation through both a juridical and an art historical perspective, to understand the systems established in early-modern and modern Europe to administer, protect, supervise, conserve, maintain, classify and record what was thought of as “heritage” in various states. Research will be carried out on original records related to legislation, including documents preserved in archives and institutes in Europe, and will involve an interdisciplinary approach to Art History, Cultural History, History of Restoration and Conservation, Legal History, Comparative Law, History of Heritage Legislation, and History of Administration. Research objectives will include an understanding of: the conceptual core of legislation; the systems of administration/supervision prescribed by law; the legal instruments provided to implement the law. Research results will include: a translation of the corpus of legislation into English; a study of the development of a consistent concept of “heritage”; a study of the practices established to administer, restore, safeguard, catalogue the heritage in 15th- to 18th-century Europe. LAWLOVE will establish a new state-of-the-art and found a first history of legislation on the protection of the artefacts in Europe, which at the moment is completely lacking, dealing also with questions related to the EU policy-making on the preservation of the heritage. A specific training-through-research will help the fellow to acquire: new research competencies; methodologies and expertise in new interdisciplinary areas; transferable skills; skills in project/financial management; writing/lecturing/communication skills. The fellow will refine her maturity and independence as academic, increasing her competitiveness for future career opportunities.";257209,92;257209,92;H2020-MSCA-IF-2018;/MSCA-IF-EF-CAR;UNIVERSITA CA' FOSCARI VENEZIA;IT;;;;1;0;0;2;0;0 212598;742138;LogNeuroDev;SIGNED;H2020-EU.1.1.;ERC-2016-ADG;H2020;The molecular and cellular logic of vertebrate neural development;2018-01-01;2022-12-31;;"A central problem in biology and key to realising the potential of regenerative medicine is understanding the mechanisms that produce and organize cells in the complex tissues of an embryo. In broad terms, initially uncommitted progenitors acquire their fate in response to signals that control transcriptional programmes. These programmes drive cells through spatial and temporal successions of states that gradually refine cell identity. How these states are established and cell fate decisions implemented is poorly understood. To address this we use an experimentally tractable system – the formation of defined populations of progenitors in the vertebrate spinal cord. We take an interdisciplinary approach that combines our in vivo expertise with three recent advances in our group. First, we have developed in vitro differentiation systems and microfluidic devices that use embryonic stem cells to recapitulate development processes. Second, we have embraced new technologies that provide unprecedented ability to manipulate and assay single cells. Finally, we have established interdisciplinary collaborations to develop computational tools and construct data driven mathematical models. Using these approaches, alongside established embryological methods, we will establish a platform for manipulating and analysing mechanisms by which the multipotent progenitors that form the spinal cord acquire specific identities. We will identify the rules by which cells make decisions and we will define the design logic and network architectures that lead to distinct cell fate choices. The ability to: (i) follow the trajectory of a cell as it transitions to a specific neuronal subtype in vivo; (ii) manipulate the process in vitro and in vivo; and (iii) model it in silico, offers a unique system for understanding organogenesis. Together these approaches will provide the knowledge and technical foundations for rational, predictive tissue engineering of the spinal cord.";2357000;2357000;ERC-2016-ADG;/ERC-ADG;THE FRANCIS CRICK INSTITUTE LIMITED;UK;;;;1;0;0;2;0;0 212312;758403;ODYSSEY;SIGNED;H2020-EU.1.1.;ERC-2017-STG;H2020;Open dynamics of interacting and disordered quantum systems;2018-07-01;2023-06-30;;"This research proposal focuses on the open quantum system dynamics of disordered and interacting many- body systems coupled to external baths. The dynamics of systems which contain both disorder and interactions are currently under intense theoretical investigation in condensed matter physics due to the discovery of a new phase of matter known as many-body localization. With the experimental realization of such systems in mind, this proposal addresses an essential issue which is to understand how coupling to external degrees of freedom influences dynamics. These systems are intrinsically complex and lie beyond the unitary closed system paradigm, so the research proposed here contains interdisciplinary methodology beyond the mainstream in condensed matter physics ranging from quantum information to quantum optics. The project has three principal objectives each of which would represent a major contribution to the field: O1. To describe the dynamics of a interacting, disordered many-body systems when coupled to external baths. O2. To perform a full characterization of spin and energy transport in their non-equilibrium steady state. O3. To explore the system capabilities as steady state thermal machine from a systematic microscopic perspective. This will be the first comprehensive study of the open system phenomenology of disordered interacting many-body systems. It will also allow for the systematic study of energy and spin transport and the exploration of the potential of these systems as steady state thermal machines. In order to successfully carry out the work proposed here, the applicant will build a world class team at Trinity College Dublin. Due to his track record and interdisciplinary background in many-body physics, quantum information and statistical mechanics combined with his personal drive and ambition the applicant is in a formidable position to successfully undertake this task with the platform provided by this ERC Starting Grant.";1333325;1333325;ERC-2017-STG;/ERC-STG;THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN;IE;;;;1;0;0;2;0;0 211568;764987;ATHOR;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2017;H2020;Advanced THermomechanical mOdelling of Refractory linings;2017-10-01;2021-09-30;;"Refractories are heat-resistant materials used as inner linings of high temperature furnaces, reactors and processing units. ATHOR (Advanced THermomechanical multiscale mOdelling of Refractory linings) is an innovative, collaborative and interdisciplinary project that brings together 6 academic beneficiaries and 8 private partners. The main objective is to develop high-end engineering technologies in material engineering and numerical simulations thanks to an intensive cooperation between academia, raw materials suppliers, refractory producers and end-users. Starting from material characterization, all significant properties will be investigated, including fracture behaviour, tension and compression creep behaviour, corrosion and thermal shock resistance. The interdisciplinary aspects will be addressed thanks to a multiscale approach looking at the influences of micro-, meso- and macro-characteristics on each other. To conduct their research and interlink the different topics, the 15 recruited researchers will take advantage of the most sophisticated numerical tools to model, design and predict the life of different lining configurations in critical operation conditions. The current financial situation of the European steel industry urges the producers to dramatically reduce their production costs. This project is expected to substantially contribute to find solutions through the design of more robust and more reliable refractory linings. Not only the total cost of refractory materials is then reduced, but the equipment’s availability and the process control are improved. In addition to the large energy savings that meet the industrial partner’s interests, the project will help to reduce the environmental impact of high temperature processes. The ATHOR network is deeply committed to provide a combination of research and training activities which will support and enlarge the initiative of the Federation for International Refractory Research and Education (FIRE).";3737239,56;3737239,56;H2020-MSCA-ITN-2017;/MSCA-ITN-ETN;UNIVERSITE DE LIMOGES;FR;"UNIVERSIDADE DO MINHO;AKADEMIA GORNICZO-HUTNICZA IM. STANISLAWA STASZICA W KRAKOWIE;MONTANUNIVERSITAET LEOBEN;RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN;UNIVERSITE D'ORLEANS";"PT;PL;AT;DE;FR";;1;0;0;2;0;0 211545;764908;WEGO;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2017;H2020;Well-being, Ecology, Gender, and cOmmunity;2018-01-01;2021-12-31;;WEGO (Well-being, Ecology, Gender and cOmmunity) is a trans-national network aims to develop a shared research and training agenda to educate the next generation of interdisciplinary social-environmental scientists on feminist political ecology in Europe. WeGO’s research examines gender relations in community organizing from a feminist-informed political ecology (FPE) framework. From an international and interdisciplinary perspective, WEGO looks at gender and power relations in community responses to the current climate, economic and environmental crises in different socio-ecological contexts. WEGO aims to provide insightful and compelling analysis about the importance of gendered community response to climate, economic and environmental change as well as more detailed knowledge about what changes are required for greater resilience and sustainability. Gender is understood as a critical variable in shaping resource access and control, interacting with class, caste, race, culture, and ethnicity to shape processes of ecological change and the prospects of any community for sustainable development. WEGO research will look at resilience and sustainability by examining the gendered role of women in care work for the community and for the environment. The cases chosen – from in and outside of Europe are sites that can feed into innovative European Policy on sustainable development.;3872821,9;3872821,9;H2020-MSCA-ITN-2017;/MSCA-ITN-ETN;ERASMUS UNIVERSITEIT ROTTERDAM;NL;"UNIVERSITY OF BRIGHTON;INSTITUTE OF DEVELOPMENT STUDIES;STICHTING IHE DELFT INSTITUTE FOR WATER EDUCATION;SVERIGES LANTBRUKSUNIVERSITET;UNIVERSITETET I OSLO;HUMBOLDT-UNIVERSITAET ZU BERLIN;WAGENINGEN UNIVERSITY;FONDAZIONE PANGEA ONLUS;FREIE UNIVERSITAET BERLIN;UNIVERSITAT PASSAU";"UK;NL;SE;NO;DE;IT";;1;0;0;2;0;0 210996;742712;CHIMO;SIGNED;H2020-EU.1.1.;ERC-2016-ADG;H2020;Chiral Morphogenesis - Physical Mechanisms of Actomyosin-Based Left/Right Symmetry Breaking in Biological Systems;2018-01-01;2022-12-31;;"The aim of this grant is to understand how cellular, tissue-scale and organismal left-right asymmetry arises from the chirality of molecular constituents. In many instances the actomyosin cortex, a thin and mechanically active layer of dynamically cross-linked filaments and molecular motors at the surface of cells, drives the emergence of chiral morphogenetic events. In the nematode Caenorhabditis elegans, mesoscale chiral active torques generated by this active layer establish the embryo’s left-right body axis. Here we want to understand how mesoscale actomyosin active torques are generated at the molecular level, and how active torque generation in the actomyosin surface drives chiral morphogenesis of cells, tissues and organisms. Cells and tissues represent a new class of active chiral materials where both the force and the torque balance need to be considered, and we will perform a systematic and cross-scale characterization of active chiral biological matter. We will pursue an interdisciplinary approach at the interface of physics and biology. At the molecular-scale, we will use optical tweezers to measure active torques generated by single molecules of the molecular myosin and the actin polymerizing protein formin. At the cell-scale, we will reconstitute chiral actomyosin flows in vitro and characterize chiral dynamics of single molecules in vivo. At the tissue-scale, we will investigate chiral cell movements in a multicellular environment and unravel the physical basis of chiral tissue flow in vertebrates. Theory is essential at all stages, and we will build a molecular-scale model of actomyosin torque generation that will be coarse-grained to a generalized hydrodynamic description of active chiral matter. This interdisciplinary and cross-scale approach will provide fundamentally new insights into active chiral materials and the mechanisms by which left-right asymmetries arise in development.";2500000;2500000;ERC-2016-ADG;/ERC-ADG;TECHNISCHE UNIVERSITAET DRESDEN;DE;;;;1;0;0;2;0;0 210464;714073;FLUINEMS;SIGNED;H2020-EU.1.1.;ERC-2016-STG;H2020;Suspended Fluidic nanochannels as optomechanical sensors for single molecules;2017-06-01;2022-11-30;;"Early detection of cancer saves lives: the survival rate increases from 10% to 90%. Today, there is a lack of methods for the early detection of different types of cancer. The main challenge is that a large variety of specific biomarkers have to be counted, and usually at extremely low concentrations. Here we will use smart nanoengineering to develop a versatile sensing platform that detects, identifies and counts single molecules, one by one, in a non-purified solution. The main novelty of the proposal is that the platform will integrate optical sensing beyond diffraction (for biochemical recognition) and on-chip molecular mass sensing (to discard non-specific binding events). For this, we will suspend state-of-the-art nanochannels and integrate them with plasmonic nano-antennas. This will make for a versatile, universal test, cheap enough to be used for preventive screening. It will help diagnosing different types of cancers earlier. We will detect and identify oncoviruses capsides, different protein biomarkers and microRNA in plasma. These are very high impact proof of concepts with clinical relevance. Dr. Fernandez-Cuesta has expertise in single molecule sensing and has worked in multiple international, interdisciplinary environments. She is expert in nanofabrication and plasmonics for (bio)sensing. She benefited from an IOF Marie Curie. She became CEO and co-founder of a start-up, dedicated to on-chip Raman spectroscopy for environmental monitoring of biotoxins concentration in fresh water. Currently, she is at the department for Applied Physics at the University of Hamburg. There, there is state-of-the-art instrumentation for nanofabrication. The collaborators at Hamburg University Klinikum Eppendorf have expertise in applying research to medicine. This interdisciplinary environment is ideal for starting a new field in combined plasmonics and mass sensing with a focus on nanotechnology for bioapplications of clinical relevance.";1500000;1500000;ERC-2016-STG;/ERC-STG;UNIVERSITAET HAMBURG;DE;;;;1;0;0;2;0;0 210162;727315;MedAID;SIGNED;H2020-EU.3.2.3.;SFS-23-2016;H2020;Mediterranean Aquaculture Integrated Development;2017-05-01;2021-04-30;;Production and productivity of Mediterranean marine fish aquaculture, mainly seabass and seabream, are stagnating or growing slowly as a result of multiple and interrelated causes. To accomplish the objective of improving its competitiveness and sustainability, MedAID is structured in a first interdisciplinary WP to assess technical, environmental, market, socioeconomic and governance weaknesses, and in several specialized WPs exploring innovative solutions, followed by an integrating WP, which will provide codes of practice and innovative tool-boxes throughout the value chain to enhance the sector performance holistically. Various stakeholders will interact in the consultation, communication, dissemination and training WPs ensuring practical orientation of the project and results implementation. Biological performance (nutrition, health and genetics) will be scrutinized to identify and quantify the relevant components to improve Key Performance Indicators (KPIs: growth rates, mortality and feed efficiency), thus contributing to increase production efficiency. Economic, business, marketing, environmental, social, administrative and legal factors will be addressed to obtain integrated solutions to shift towards a market-oriented and consumer-responsible business and to face the multiple administrative, environmental and social issues constraining competitiveness and public acceptance. An interdisciplinary consortium of research and industrial partners will carry out R&D and case study activities to close the existing gaps. Mediterranean countries (EU and non-EU) with significant aquaculture production are represented. Northern European R&D institutions will participate by bringing successful technological tools and integrated approaches that Mediterranean aquaculture is missing today. MedAID will impact the sector positively by providing innovative tools, integrated marketing and business plans and by improving the sector image, sustainability and governance.;6999996,25;6999996,25;H2020-SFS-2016-2;/RIA;Mediterranean Agronomic Institute of Zaragoza / International Centre for Advanced Mediterranean Agronomic Studies;ES;"AARHUS UNIVERSITET;FOOD AND AGRICULTURE ORGANIZATION OF THE UNITED NATIONS FAO;VETERINAERINSTITUTTET - NORWEGIAN VETERINARY INSTITUTE;NISEA SOCIETA COOPERATIVA;HRVATSKI VETERINARSKI INSTITUT;HELLENIC CENTRE FOR MARINE RESEARCH;UNIVERSITE DE BRETAGNE OCCIDENTALE;ISTITUTO ZOOPROFILATTICO SPERIMENTALE DELLE VENEZIE;AZIENDA ITTICA IL PADULE DI FORNACIARI NAIDA & C SOCIETA AGRICOLA SEMPLICE;SELARL DU DOCTEUR ALAIN LE BRETON;NOFIMA AS;KOBENHAVNS UNIVERSITET;NATIONAL INSTITUTE OF OCEANOGRAPHY AND FISHERIES;INSTITUTO NACIONAL DE INVESTIGACION Y TECNOLOGIA AGRARIA Y ALIMENTARIA OA MP;SAMFUNNS-OG NAERINGSLIVSFORSKNING AS;COMPAGNIE ITTICHE RIUNITE SOCIETA'AGRICOLA SRL;DIBAQ DIPROTEG SA;UNIVERSIDAD DE MURCIA;SCEA LES POISSONS DU SOLEIL;GALAXIDI MARINE FARM AE;CENTRO DE CIENCIAS DO MAR DO ALGARVE;EGE UNIVERSITY;ISIDRO 1952 SL;INSTITUT DE RECERCA I TECNOLOGIA AGROALIMENTARIES;AVDELAS LAMPRAKIS;DANMARKS TEKNISKE UNIVERSITET;INSTITUT FRANCAIS DE RECHERCHE POUR L'EXPLOITATION DE LA MER;ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA;FUNDACION AZTI - AZTI FUNDAZIOA;UNIVERSIDAD DE CANTABRIA;WAGENINGEN UNIVERSITY;Institut National des Sciences et Technologies de la Mer;THE UNIVERSITY OF EDINBURGH;STICHTING WAGENINGEN RESEARCH";"DK;IT;NO;HR;EL;FR;EG;ES;PT;TR;NL;TN;UK";;1;0;0;2;0;0 209344;750865;CDSANAB;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Complex Dynamics and Strange Attractors through Non-Autonomous Bifurcations;2018-03-01;2020-07-31;;"This project aims at substantial contributions to the bifurcation theory of non-autonomous dynamical systems. The main research efforts will focus on an analytical investigation of the principles behind the creation of complex dynamical behaviour and strange attractors in the most common kinds of non-autonomous bifurcations: saddle-node and Hopf bifurcations. The project further aims at an interdisciplinary application of the analytical findings to the problem of the predictability of ice ages. The research on non-autonomous saddle-node bifurcations will extend the results of the applicant's PhD. Here, the main strategy is to apply powerful multiscale analysis techniques. Further, it is aimed at providing easily applicable tools for researchers in the life sciences to reliably track complex behaviour near saddle-node bifurcations. The research on the non-autonomous Hopf bifurcation will focus on the creation of chaos. In deterministically driven systems, the analysis will again be based on multiscale analysis techniques. In randomly driven systems, it is aimed at a profound extension of the work by the supervisor and his collaborators on shear-induced chaos. The host institution is not only a leading centre in bifurcation theory and non-autonomous dynamics but also the coordinating institution of the Marie Sk³odowska-Curie Innovative Training Network (ITN) CRITICS which addresses critical transitions in complex systems. The interdisciplinary part of the project will be dealt with in collaboration with a partner of this ITN: the Theoretical Climate and Palaeoclimate Dynamics group at the Université catholique de Louvain. The Horizon 2020 key challenges include topics such as food security or climate action. Appropriate measures addressing related issues need to rely on a good understanding of complex systems which are non-autonomous by nature. Thus, profound insights into non-autonomous systems and bifurcations of such systems are of an immense European interest.";183454,8;183454,8;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE;UK;;;;1;0;0;2;0;0 208873;745896;HISTPLAY;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;The History Play and the British Enlightenment, 1750-1815;2017-06-01;2019-08-31;;"The aim of this Fellowship is for the researcher, Dr David O’Shaughnessy, to develop the professional prowess, advanced training, high-impact dissemination, and practical experience commensurate with a leading independent researcher in the EU. The researcher will be based for 15 months at the Huntington Library, California (HL) supervised by Professor Kevin Gilmartin and for 12 months at the School of English, Trinity College Dublin (TCD) supervised by Dr Aileen Douglas. Research training will be implemented through an interdisciplinary project investigating the importance of the history play to the discussion and dissemination of Enlightenment ideas in the two main London theatres of the eighteenth century, Covent Garden and Drury Lane, 1750-1815. The key output will be the first monograph to be written on the eighteenth-century history play but the project will also communicate knowledge to a public audience through appropriate activities. On the outgoing phase of the Fellowship, the researcher will access expertise, advanced training, mentoring as well as having access to the Larpent Collection of theatre manuscripts at the HL, the most important archive in the world for the study of eighteenth-century theatre. Due to its unique archive holdings, the HL is the only institution in the world that can host this project; it also has collaborative relationships with Caltech and the University of Southern California (USC) which will benefit the research in significant ways. In TCD the researcher will be given the opportunity to embed his new knowledge through undergraduate and postgraduate teaching, conferences and a symposium, and continued research. The resources of the host institutions will facilitate development of an interdisciplinary and international academic network as well as career-mentoring. The Fellowship will establish the researcher firmly at the centre of eighteenth-century theatre studies and position him for a successful ERC Consolidator application.";201514,5;201514,5;H2020-MSCA-IF-2016;/MSCA-IF-GF;THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN;IE;;;;1;0;0;2;0;0 206909;700196;LiveDeadFossil;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Life and death in Do?ana National Park (Spain): palaeontological and ecological insights from the study of modern vertebrate death assemblages;2017-02-01;2019-01-31;;Taphonomy is the interdisciplinary science, between the fields of biology and geology, that evaluates the transition of live organisms into death assemblages and, eventually, into fossil remains. Modern death assemblages provide a basis for understanding what components of living communities may be preserved in the fossil record and what biases are to be expected. Also, methods and discoveries of taphonomic research in modern ecosystems are of value to ecologists because skeletal remains hold a wealth of information about the vertebrate species inhabiting an ecosystem. Despite the interdisciplinary information that these studies contain, naturally occurring bone accumulations are largely unexplored and have not been studied neither in the European realm nor in a Mediterranean ecosystem. We propose here a training-through-research project based on the taphonomic monitoring and fidelity evaluation of the vertebrate death assemblage (mainly >5 kg terrestrial vertebrates) of a UNESCO World Heritage Site, Do?ana National Park (DNP) (Spain). The candidate has experience in the taphonomic reconstruction of fossil sites but has limited exposure to taphonomic field techniques and analyses of modern death assemblages and live:dead fidelity studies. The LiveDeadFossil project will broaden her professional experience and contribute to her growth as independent researcher. The research will shed light on the ecological and post-mortem processes undergone by vertebrate remains in a Mediterranean ecosystem and will complement the study and management of the vertebrate communities of the park. The selected host organization, Do?ana Biological Station-CSIC (Seville, Spain), is a world-class research center for ecology and conservation biology, manages all the activities at DNP and has all the facilities and services in place (including population census data, osteological collections, laboratories, etc.) for the successful fulfilment of this training and research programme.;158121,6;158121,6;H2020-MSCA-IF-2015;/MSCA-IF-EF-RI;AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS;ES;;;;1;0;0;2;0;0 193973;642976;NanoHeal;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2014-ETN;H2020;Nano-tailoring organo-mineral materials -Controlling strength and healing with organic molecules in mineral interfaces;2015-01-01;2018-12-31;;"Cement production for the construction industry contributes up to 5% of anthropogenic CO2 emissions. Developing more environmentally friendly concrete requires the assessment of strength for a diverse range of new cement materials. Similar issues arise during the development of biocompatible cements for medical applications. Properties of naturally cemented materials of organic origin are of key importance in the oil industry, with carbonate reservoirs prone to creep, particularly during the injection of CO2 for enhanced oil recovery or permanent storage. However, despite the importance of cement materials to our infrastructure, health and environment, we still lack the fundamental basis for understanding the strength of cemented aggregates. Granular pastes and sediments transform to strong solids through reactions at nano-confined mineral interfaces, where nucleation and growth at the adjacent solid surfaces are affected in a manner not yet understood. There is a need for improved concepts, theories and models. NanoHeal targets this issue by bringing six industrial and six academic groups together in a European Training Network (ETN), in an emerging interdisciplinary field spanning from basic sciences to the corresponding engineering disciplines. NanoHeal will deliver an outstanding environment for training and career development of young researchers. The aims of NanoHeal are to: • develop innovative probes and models for nanoscale processes that open novel perspectives in design and control of organo-mineral materials. • measure and improve the strength and durability of 1) new man-made cemented materials like “green concrete”, speciality cements in construction and oil and gas recovery, and biocompatible implants and 2) natural sedimentary rocks inside reservoirs and as construction materials • educate young interdisciplinary researchers at the interface between fundamental science and European industry.";4103572,68;4103572,68;H2020-MSCA-ITN-2014;/MSCA-ITN-ETN;UNIVERSITETET I OSLO;NO;"FRIEDRICH-ALEXANDER-UNIVERSITAET ERLANGEN NUERNBERG;UNIVERSITE LYON 1 CLAUDE BERNARD;IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE;KOBENHAVNS UNIVERSITET;INTERNATIONAL RESEARCH INSTITUTE OFSTAVANGER AS;TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY;NORCE NORWEGIAN RESEARCH CENTRE AS";"DE;FR;UK;DK;NO;IL";;1;0;0;2;0;0 193479;637295;X-probe;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2014-ETN;H2020;Advanced XFEL and Synchrotron based Probes of Protein Structure and Dynamics;2015-01-01;2018-12-31;;"This cross-disciplinary Marie Curie Innovative Training Network builds upon the transformative opportunities created by existing X-ray sources and new sources soon to be operative in Europe. These opportunities include using ultrafast X-ray sources to extract time-dependent structural information from proteins; and revolutionary possibilities created by X-ray Free Electron Laser radiation for an entirely new regime of pre-damage serial femtosecond crystallography. No lag should exist between building new sources and training the next generation of scientists well versed in using these facilities. Our research training will yield new scientific insights on fundamental properties of protein structure and dynamics: one of the most challenging problems in structural biology; and technological advancements in diverse fields from pharmacology to nanotechnology. X-probe creates close interdisciplinary collaboration between structural biologists, physical chemists, beamline engineers, software developers, and industrial partners. The rapidly changing state-of-the-art demands that young researchers are trained to meet these new experimental, technical and analysis challenges at the forefront of structural biology and photochemistry. X-probe’s interdisciplinary and intersectorial training network incorporates four leading European X-ray facilities (ESRF, MAXIV Laboratory, European XFEL, SwissFEL); three academic laboratories at the forefront developing X-ray tools to probe protein dynamics; and both large and small industrial partners. Four principal scientists in X-probe are female. X-probe builds close cooperation between traditionally separate fields of research at the very cutting edge of structural biology and creates a visionary training network that would not be possible within any of the individual partner states.";2331284,76;2331284,76;H2020-MSCA-ITN-2014;/MSCA-ITN-ETN;UNIVERSITA DEGLI STUDI DI ROMA LA SAPIENZA;IT;"LUNDS UNIVERSITET;EUROPEAN SYNCHROTRON RADIATION FACILITY;ASTRAZENECA AB;UNIVERSITAET HAMBURG;XTAL CONCEPTS GMBH;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;GOETEBORGS UNIVERSITET;MOLIROM SRL";"SE;FR;DE;IT";;1;0;0;2;0;0 206522;734907;3D NEONET;SIGNED;H2020-EU.1.3.3.;MSCA-RISE-2016;H2020;Drug Discovery and Delivery NEtwork for ONcology and Eye Therapeutics;2017-01-01;2020-12-31;;"Severe ocular disorders are affecting the lives of more than 100Mill people world-wide and at least 25% of the population above 70 years of age, a growing demographic group in EU. More than 8 million people lose their lives to cancer every year, making cancer a leading cause of pre-mature mortality in the world. The main hallmarks of severe eye conditions (i.e angiogenesis, inflammation and vascular permeability) play also pivotal roles in cancer, being therapeutic targets to treat both kind of diseases. The overall goal of 3D-NEONET is the improvement of available treatments for cancer and ocular disease by enhancing drug discovery-development and delivery to targeted tissues, through advanced international co-operation between academic and non-academic partners. The interdisciplinary expertise provided by 18 partners in 7 countries encompasses among others: drug screens, ADME, toxicology, preclinical models, nanotechnology, biomaterials and clinical trials. After the success with ongoing FP7-IAPP project 3D-NET (Drug Discovery and Development of Novel Eye Therapeutics; (www.ucd.ie/3dnet), we are assembling 3D-NEONET, this enlarged European interdisciplinary consortium that will join forces and exchange skills to enhance current therapies in oncology and ophthalmology. The 3 global objectives of 3D-NEONET are: 1- Enhance the discovery and development of novel drugs, targets and biomarkers for ophthalmology and oncology. 2- Improve the Delivery of Therapeutics for Oncology and Ophthalmology 3- Enhancement of Research, Commercial and Clinical Trial Project Management Practices in these fields. Through participation in the program, 3D-NEONET is the vehicle for driving synergies between academic and non-academic partners leading to increased scientific and technological excellence as well as tangible innovative outputs that will strengthen the competitiveness of both the researchers and industries of the network even beyond the lifetime of the network.";945000;945000;H2020-MSCA-RISE-2016;/MSCA-RISE;UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN;IE;"LINKOPINGS UNIVERSITET;NATIONAL UNIVERSITY OF IRELAND GALWAY;BLAFAR LIMITED;UNIVERSIDAD DE VALLADOLID;EXPERIMENTELLE PHARMAKOLOGIE UND ONKOLOGIE BERLIN-BUCH GMBH;THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN;ICON CLINICAL RESEARCH LIMITED;OCUPHARM DIAGNOSTICS SL;ASHLAND SPECIALTIES IRELAND LIMITED;THE QUEEN'S UNIVERSITY OF BELFAST;UNIVERSIDAD COMPLUTENSE DE MADRID;KARLSRUHER INSTITUT FUER TECHNOLOGIE;ZECLINICS SL;XENOPAT SL;ECM INGENIERIA AMBIENTAL SL;LABORATORIO IBERICO INTERNACIONAL DE NANOTECNOLOGIA;HGBEYOND MATERIALS SICENCE SL";"SE;IE;ES;DE;UK;PT";;1;0;0;2;0;0 206473;714102;CaBiS;SIGNED;H2020-EU.1.1.;ERC-2016-STG;H2020;Chemistry and Biology in Synergy - Studies of hydrogenases using a combination of synthetic chemistry and biological tools;2017-02-01;2022-01-31;;"My proposal aims to take advantage of my ground-breaking finding that it is possible to mature, or activate, the [FeFe] hydrogenase enzyme (HydA) using synthetic mimics of its catalytic [2Fe] cofactor. (Berggren et al, Nature, 2013) We will now explore the chemistry and (bio-)technological potential of the enzyme using an interdisciplinary approach ranging from in vivo biochemical studies all the way to synthetic model chemistry. Hydrogenases catalyse the interconversion between protons and H2 with remarkable efficiency. Consequently, they are intensively studied as alternatives to Pt-catalysts for these reactions, and are arguably of high (bio-) technological importance in the light of a future “hydrogen society”. The project involves the preparation of novel “artificial” hydrogenases with the primary aim of designing spectroscopic model systems via modification(s) of the organometallic [2Fe] subsite. In parallel we will prepare in vitro loaded forms of the maturase HydF and study its interaction with apo-HydA in order to further elucidate the maturation process of HydA. Moreover we will develop the techniques necessary for in vivo application of the artificial activation concept, thereby paving the way for a multitude of studies including the reactivity of artificial hydrogenases inside a living cell, but also e.g. gain-of-function studies in combination with metabolomics and proteomics. Inspired by our work on the artificial maturation system we will also draw from our knowledge of Nature’s [FeS] cluster proteins in order to prepare a novel class of “miniaturized hydrogenases” combining synthetic [4Fe4S] binding oligopeptides with [2Fe] cofactor model compounds. Our interdisciplinary approach is particularly appealing as it not only provides further insight into hydrogenase chemistry and the maturation of metalloproteins, but also involves the development of novel tools and concepts applicable to the wider field of bioinorganic chemistry.";1494880;1494880;ERC-2016-STG;/ERC-STG;UPPSALA UNIVERSITET;SE;;;;1;0;0;2;0;0 203313;703873;BroWoun;CLOSED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Brothers in Wounds: Italy's Disabled Veterans in Transnational Perspective (1917-1939);2016-10-01;2018-09-30;;"This innovative project aims to investigate the return to civilian life, throughout the interwar period (1917-1939), of servicemen who had been physically injured on the battlefields of the First World War. It will focus on Italy to develop an interdisciplinary, multi-scalar, and transnational approach to the rehabilitation and reintegration of disabled veterans. The project will thus lay the foundation for a truly European history of war disability in the twentieth-century. By mobilizing a wide range of primary sources and combining different historiographical approaches, this project will bring to light the specific experiences of Italian disabled ex-servicemen, determined as they were by the country’s political culture, institutional structure, and patterns of social relations. While remaining attentive to national specificities, it will highlight the common responses and attitudes that emerged across belligerent nations. The project will thus contribute to a transnational history of the transition from war to peace and of the stabilization of Europe in the inter-war era. The adoption of an interdisciplinary approach and the mobilization of intellectual tools forged by other disciplines will help formulating an appropriate analytical response to the complex physical, psychological, and social challenges faced by disabled veterans. This project will therefore make a historical contribution to current reflections on the reintegration of disabled veterans in post-conflict societies. Addressing a matter of continuing concern, it will help inform contemporary debates in academic, medical and policy-making circles.";183454,8;183454,8;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;THE UNIVERSITY OF WARWICK;UK;;;;1;0;0;2;0;0 201155;703530;DynOMIS;CLOSED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Dynamic Origins of MHC class I Selector function;2016-09-06;2018-09-05;;"DynOMIS aims to elucidate the antigen selection mechanisms of the adaptive immune system at the molecular level in the highly complex cellular environment. Major histocompatibility complex class I molecules (MHC-I) is a key mediator of adaptive immunity, the cell’s arsenal against infectious pathogens and malignant transformations. MHC-I present antigenic peptides to cytotoxic T lymphocytes at the cell surface, which in turn unleash their cytotoxic apparatus only when peptides from non-healthy proteins are recognized. This process is the result of an equally important peptide selecting function in the early secretory pathway, a mechanism that has not been clearly understood in spite of its fundamental role in vaccination. Deep understanding of the exact mechanisms that drive peptide selection by MHC-I will help to predict immunoprotective epitopes in infections and cancer, which will in turn pave the way for the development of more effective T cell-targeting vaccines and biomarkers to stratify patients’ suitability for immunotherapy. DynOMIS will employ a sophisticated, interdisciplinary approach that integrates quantitative computational systems modelling to identify molecular mechanism from cellular biochemical information, experimental investigation of the structure and dynamics of peptide-bound MHC-I over a large range of timescales, and state-of-the-art molecular dynamics simulations and free energy calculations to elucidate the thermodynamic basis of the peptide selection mechanism in the context of their interactions with cellular cofactors. To this end, DynOMIS will be carried out by an experienced researcher at a world-leading interdisciplinary group comprising molecular immunologists, structural biologists, computational chemists, and industrial partners with a strong focus on clinically relevant immunological research.";195454,8;195454,8;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;UNIVERSITY OF SOUTHAMPTON;UK;;;;1;0;0;2;0;0 201292;705090;Ex Anatolia lux;CLOSED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Ex Anatolia lux. The Linguistic Origins of Europe: Word-formation and Lexicon in Anatolian and Core Indo-European.;2016-10-01;2018-09-30;;The understanding of the linguistic origins of Europe begins with Proto-Indo-European (PIE), the reconstructed language from which all Indo-European (IE) languages descend, including modern languages like English, Spanish, Russian and Hindi, and are spoken by more than half of the world’s population. In particular, a proper understanding of Proto-Indo-European begins with the extinct Anatolian languages, e.g. Hittite and Lycian, known from ancient clay tablets and inscriptions and spoken in the Asian part of Turkey and part of northern Syria during 16th-2nd century BCE. The Anatolian branch plays a key role since it was the first to split off from the IE language family and has several specific features, which are not shared by other IE languages. As the first of its kind, this project will shed light on the position and development of Anatolian in relation to the rest of the IE family by a systematic study of Anatolian word formation and vocabulary. The results will integrate a ‘free access database' established 2013 by the Research Centre ‘Roots of Europe’ (RoE), which will also be a new useful research instrument for other disciplines as philology, epigraphy and archaeology in a perspective of interdisciplinary collaboration and mutual benefit. The Roots of Europe, headed by my supervisor Prof. B. A. Rasmussen (Olsen) and based at the Department of Nordic Studies and Linguistics of the UCPH, is the most appropriate institution for this project: the scientific expertise and interdisciplinary profile of the research team in the topics involved in the research, including a specific project of the IE homeland, the training and the knowledge transfer will be the winning combination not only for the achievements of the goals set up for my project, but also to make my profile as an independent researcher more competitive.;200194,8;200194,8;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;KOBENHAVNS UNIVERSITET;DK;;;;1;0;0;2;0;0 200042;680088;SCHISTO_PERSIST;SIGNED;H2020-EU.1.1.;ERC-StG-2015;H2020;New approaches to characterise Schistosoma mansoni infections persisting despite mass drug administration;2016-04-01;2021-03-31;;"Neglected tropical diseases affect over 1.4 billion people and cause a greater disease burden than HIV/AIDS. Despite extensive mass drug administration (MDA) schistosomiasis remains a major public health issue, with a socio-economic impact second only to malaria amongst parasites. I will evaluate novel strategies and new technologies to monitor the impact of MDA programmes, to identify threats to MDA effectiveness, and enhance control of schistosomiasis in sub-Saharan Africa. Specifically I will address five ambitious questions: 1. What is the best way to monitor schistosome infections and drug efficacy? 2. Has drug resistance been selected for? 3. What is the potential for drug resistance to spread? 4. What other factors drive transmission? 5. What other factors affect parasite clearance? These aims are feasible through innovative interdisciplinary methods including a) state-of-the-art DNA-chip diagnostics, b) novel application of genetic analysis to differentiate surviving worms from juveniles, c) use of drug screening technology to measure in vitro drug susceptibility, providing the first quantifiable in vitro phenotype without using mammals, d) combination of molecular techniques with mathematical models to elucidate the potential spread of phenotypes and e) an unparalleled interdisciplinary approach deducing host effects in non-clearers. These methods and technologies have not previously been used to assess MDA effectiveness for any helminth infection. My pioneering research will enable a comparative assessment of how transmission is affected by untreated adults and pre-school children, individuals with heavy infections, coinfections, and drug coverage. This will elucidate optimal strategies to reduce transmission hotspots. My results will improve monitoring protocols and inform policy makers on how best to treat schistosomiasis. I will fill a critical global health knowledge gap, with findings transferable across a range of MDA controlled diseases.";1490270;1490270;ERC-2015-STG;/ERC-STG;UNIVERSITY OF GLASGOW;UK;;;;1;0;0;2;0;0 205461;722826;GEM-STONES;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2016;H2020;Globalisation, Europe and Multilateralism - Sophistication of the Transnational Order, Networksand European Strategies;2016-09-01;2020-08-31;;"'This is a European Joint Doctorat (EJD) gathering 16 partner organizations from 3 different continents. It includes 5 EU HEIs, 3 non-EU HEIs, 3 Think Tanks, 2 MNEs, 1 SME, 1 NPO & 1 EU Intitution. It's shared research agenda on 'Globalisation, Europe and Multilateralism' seeks to unpack the growing 'Sophistication of the Transnational Order, Networks and European Strategies' in light of the EU's attempts at regime complex management. To this effect, the EU's response to international institutional proliferation is alternatively analyzed through the lens of its ability to provide purposeful complex regime management in light of its institutional capacities, network capacities, relative capacities and framing capacities. Collectively GEM-STONES will increase the breath of regime complex management theory as its postulates are confronted with the specific experience of the EU. The project will also expand the state-of-the art in EU studies, notably on the EU's external action. The research will ultimately sketch a nuanced, innovative, and interdisciplinary answer to the question: how does the EU contributes towards the management of institutional proliferation? To meet this research objective, while also strengthening the EU's innovation capacities, GEM-STONES will select and train 15 highly competitive ESRs. Its chosen interdisciplinary research and training methods bridg a variety of SSH disciplines. Each ESR will accomplish a specific research project as part of the overall agenda. Ultimately, if successful, ESRs will be awarded a Double Degree from two of the project's HEIs. Training is to be an integrated curriculum designed to foster structured PhD training at the EU level, and allow for novel public-private collaborations. The 180 ECTS worth of training will be provided through research, education & practice and will incl. a significant internship.'";3843713,31;3843713,31;H2020-MSCA-ITN-2016;/MSCA-ITN-EJD;UNIVERSITE LIBRE DE BRUXELLES;BE;"THE TRANSATLANTIC FOUNDATION;LUISS LIBERA UNIVERSITA INTERNAZIONALE DEGLI STUDI SOCIALI GUIDO CARLI;UNIVERSITAET HAMBURG;THE UNIVERSITY OF WARWICK";"BE;IT;DE;UK";;1;0;0;2;0;0 205537;722626;FiBreMoD;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2016;H2020;Fibre break models for designing novel composite microstructures and applications;2016-10-01;2020-09-30;;Limiting the climate change-induced temperature increase to less than 2°C will require strong reductions in greenhouse gas emissions. Lightweight materials and fibre-reinforced composites in particular, are a key enabling technology to achieve this goal. Current composite applications are however strongly overdesigned due to a lack of reliable design tools and predictive models for their mechanical properties. Developing, using and applying these models requires interdisciplinary researchers with a strong background in both modelling and experiments, but such researchers are scarce. The 9 beneficiaries and 3 partner organisations in FiBreMoD aim to train 13 such researchers to become multi-talented and interdisciplinary researchers that will be highly coveted in the field of composites. They will be intensively trained by leading experts with world-class facilities and will be supported by a strong industry participation and an extensive international network. The training programme places a strong emphasis on entrepreneurship and innovation skills not only by dedicated workshops but also by the involvement of the researchers in potential commercialisation. This approach will be key to improving the EU’s innovation capacity. Simultaneously, the researchers will advance state-of-the-art composite failure models to reach the required levels of accuracy and develop advanced and industry-friendly characterisation techniques for measuring the required input data. The goal will be to enable blind predictions, which means that parameter fitting or tuning of the models is no longer required. These new and unprecedented levels of understanding coupled with improved prediction accuracy will be exploited to (1) design novel microstructures for hybrid, hierarchical and discontinuous fibre composites and (2) increase the usefulness of models in practical composite applications. The developed models will be validated and used to design composite cylinders and automotive parts.;3370807,44;3370807,44;H2020-MSCA-ITN-2016;/MSCA-ITN-ETN;KATHOLIEKE UNIVERSITEIT LEUVEN;BE;"IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE;WEIZMANN INSTITUTE OF SCIENCE LTD;TOYOTA MOTOR EUROPE NV;CHOMARAT TEXTILES INDUSTRIES;SIEMENS INDUSTRY SOFTWARE NV;UNIVERSITY OF SOUTHAMPTON;BUNDESANSTALT FUER MATERIALFORSCHUNG UND -PRUEFUNG;ECOLE NATIONALE SUPERIEURE DES MINES DE PARIS";"UK;IL;BE;FR;DE";;1;0;0;2;0;0 203539;711792;LiRichFCC;SIGNED;H2020-EU.1.2.1.;FETOPEN-RIA-2014-2015;H2020;A new class of powerful materials for electrochemical energy storage: Lithium-rich oxyfluorides with cubic dense packing;2016-10-01;2019-09-30;;"The LiRichFCC project will explore an entirely new class of materials for electrochemical energy storage termed “Li-rich FCC” comprising a very high concentration of lithium in a cubic dense packed structure (FCC). The process by which energy is stored in these materials constitutes a paradigm change in the design of battery materials and involves unexpected and surprisingly effective mechanisms: instead of storing lithium ions by intercalation into a stable host, lithium ions are populating and vacating lattice sites of the material itself. This new principle allows for unprecedented energy and power density compared to other battery materials and may revolutionize the use of batteries in applications involving a need for supplying large amounts of energy and power from small spaces. Li-rich FCC materials have just been discovered by one of the partners of the consortium, and the possible chemical compositions, properties, and charge storage principle associated with this new materials class are far from being understood. Thus, it is the aim of the project to explore and optimize possible compositions, synthesis methods, structural properties and dynamics of Li-rich FCC materials through an interdisciplinary approach involving predictive computational work, advanced chemical synthesis and high-end characterization. An important focus of the project will further be to evaluate the use of these materials for electrical energy storage and to identify potential other uses for Li-rich FCC materials that cannot be foreseen today. Due to the inherent paradigm change and the high promise Li-rich FCC materials hold both in regards to fundamental science as well as to battery applications, LiRichFCC fulfils all the preconditions of the call. The project is based on the long-term vision to develop a novel class of materials into practical use, involving foundational aspects in S&T with breakthrough character, high novelty and risk, and a broad, interdisciplinary approach.";4114753,75;4114753,5;H2020-FETOPEN-2014-2015-RIA;/RIA;KARLSRUHER INSTITUT FUER TECHNOLOGIE;DE;"COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES;UPPSALA UNIVERSITET;KEMIJSKI INSTITUT;DANMARKS TEKNISKE UNIVERSITET";"FR;SE;SI;DK";;1;0;0;2;0;0 200476;676129;ESA -ITN;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2015-ETN;H2020;European Sepsis Academy: towards new biomarkers to improve sepsis management;2016-03-01;2020-02-29;;"ESA-ITN will break through the state of the art in sepsis diagnostics and will train 15 early-stage researchers (ESRs) to determine the clinical potency of a variety of new complementary sepsis biomarkers. These cover the full range of the antiinflammatory response in sepsis, at genetic, molecular and cellular level. Rapid and practical biomarker diagnostics for sepsis will be developed by building on some of the world's most innovative diagnostic platforms. In addition, a whole new clinical research model that incorporates use of biomarker diagnostics will be designed and tested. All 15 interlinked ESR projects have an interdisciplinary component (intersection of sepsis research, product development, economics and medical practice) and international (representing 10 countries) and industry collaborations (incorporating 3 diagnostics firms, 1 bioinformatics company and a business school). Interactions within the network are strengthened by meaningful secondments, which take place at private beneficiary or partner institutes. The training programme covers: 1. Specialist training in an international, interdisciplinary and intersectorial sepsis-orientated research project; 2. Advanced technology training in pathogenesis, biomarker discovery, diagnostics, trial design and innovation management; 3. Professional training in transferable skills, including the special ESA-ITN mini-MBA. The setup of ESA-ITN is unique as it reflects the entire innovation value chain for sepsis biomarker diagnostics. ESA-ITN is composed of leading institutes in sepsis research and a selection of Europe's top biomarker diagnostics companies. Links to various global networks and shared research infrastructures in the field of sepsis further leverage the proposition of ESA-ITN.";3895551;3895551;H2020-MSCA-ITN-2015;/MSCA-ITN-ETN;AMC MEDICAL RESEARCH BV;NL;"ETHNIKO KAI KAPODISTRIAKO PANEPISTIMIO ATHINON;CENTRE HOSPITALIER UNIVERSITAIRE VAUDOIS;BIOMERIEUX SA;HUMANITAS MIRASOLE SPA;UNIVERSITY COLLEGE LONDON;Academisch Medisch Centrum bij de Universiteit van Amsterdam;INSTITUT EUROPEEN D ADMINISTRATION DES AFFAIRES";"EL;CH;FR;IT;UK;NL";;1;0;0;2;0;0 198330;676434;BIGCHEM;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2015-EID;H2020;Big Data in Chemistry;2016-01-01;2019-12-31;;The advent of the big data era in chemistry and the life sciences requires the development of new computational analysis methods, which are not only of scientific, but also economic relevance. Currently, the international data market already grows six times faster than the entire IT sector, and growth rates further increase. Achieving and sustaining a leadership positions in the big data arena represent critically important challenges for the EU. The economic developments in the emerging big data field are science-driven. Due to complexity and heterogeneity of biochemical and biomedical data, large-scale data exploration and exploitation are intrinsically interdisciplinary tasks. BIGCHEM positions itself at interfaces between chemistry, computer science, and the life science to provide well-structured multidisciplinary training and educate high-in-demand computational specialists capable of operating in interdisciplinary and international research and business settings. Cornerstones of BIGCHEM’s curriculum include on-line lectures and periodic schools taught by internationally leading experts in chemical and life science informatics, a balanced consortium of academia, SMEs, and large industry, and an unprecedented symbiosis of academic and industrial training and application components. Accordingly, BIGCHEM is well positioned to boost multilateral collaborations between academia and industry and train scientists who are highly competitive in the international big data market. In BIGCHEM’s R&D and training activities, the development and evaluation of conceptually novel methods for large-scale data analysis, knowledge extraction, and information sharing with demonstrated practical application potential take center stage. The network has a clearly defined policy for exploitation of new IP through wide involvement of target users, SMEs, and large industry facilitated by the experienced technology transfer department of the coordinator's team.;2555534,16;2555534,16;H2020-MSCA-ITN-2015;/MSCA-ITN-EID;HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH;DE;"ASTRAZENECA AB;UNIVERSITAET BERN;UNIVERSITE DE STRASBOURG;BOEHRINGER INGELHEIM PHARMA GMBH &CO KG;LEAD DISCOVERY CENTER GMBH;RHEINISCHE FRIEDRICH-WILHELMS-UNIVERSITAT BONN;EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH;UNIVERSITA DEGLI STUDI DI MODENA E REGGIO EMILIA";"SE;CH;FR;DE;IT";;1;0;0;2;0;0 206095;731264;SHAPE-ENERGY;SIGNED;H2020-EU.3.3.6.;LCE-32-2016;H2020;Social Sciences and Humanities for Advancing Policy in European Energy;2017-02-01;2019-01-31;;"SHAPE-ENERGY “Social Sciences and Humanities for Advancing Policy in European Energy” will develop Europe’s expertise in using and applying energy-SSH to accelerate the delivery of Europe’s Energy Union Strategy. Our consortium brings together 7 leading academic partners and 6 highly respected policy, industry and communications practitioners from across the Energy, Social Sciences and Humanities (energy-SSH) research field, to create an innovative and inclusive Platform. Our partners are involved in numerous European energy projects, have extensive, relevant networks in the energy domain, and represent exceptional coverage across SSH disciplines across Europe. These enable us to maximise the impact of our Platform delivery within an intensive 2-year project. SHAPE-ENERGY brings together those who ‘demand’ energy-SSH research and those who ‘supply’ that research to collaborate in ‘shaping’ Europe’s energy future. A key deliverable will be a “2020-2030 research and innovation agenda” to underpin post-Horizon 2020 energy-focused work programmes. It will highlight how energy-SSH can be better embedded into energy policymaking, innovation and research in the next decade. Our SHAPE-ENERGY Platform activities will involve >12,114 stakeholders and begin with scoping activities including: an academic workshop, call for evidence, interviews with business leaders and NGOs, online citizen debates and multi-level policy meetings. We will build on our scoping to then deliver: 18 multi-stakeholder workshops in cities across Europe, an Early Stage Researcher programme, Horizon 2020 sandpits, interdisciplinary think pieces, a research design challenge, and a pan-European conference. Our expert consortium will bring their considerable expertise to overcome difficulties in promoting interdisciplinary and cross-sector working, and reach out to new parts of Europe to create an inclusive, dynamic and open Platform. SHAPE-ENERGY will drive forward Europe’s low carbon energy future.";1996573,75;1996573,75;H2020-LCE-2016-ERA;/CSA;ANGLIA RUSKIN UNIVERSITY HIGHER EDUCATION CORPORATION;UK;"ENERGY CITIES/ENERGIE-CITES ASSOCIATION;ACENTOLINE COMUNICACION EDITORA SL;EUROPEAN COUNCIL FOR AN ENERGY EFFICIENT ECONOMY FORENING - ECEEE;UNIVERZITA TOMASE BATI VE ZLINE;DUNEWORKS BV;ECOLE NATIONALE DES TRAVAUX PUBLICS DE L'ETAT;KARLSRUHER INSTITUT FUER TECHNOLOGIE;POLITECNICO DI TORINO;FRIENDS OF EUROPE - LES AMIS DE L'EUROPE;NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU;MIDDLE EAST TECHNICAL UNIVERSITY;BLACK SEA ENERGY RESEARCH";"FR;ES;SE;CZ;NL;DE;IT;BE;NO;TR;BG";;1;0;0;2;0;0 202568;679873;MONASS;SIGNED;H2020-EU.1.1.;ERC-StG-2015;H2020;MONSOON ASSEMBLAGES;2016-05-01;2021-04-30;;"The ambition of this cutting edge research project is to deliver a ground breaking, interdisciplinary design-driven inquiry into the impacts of changing monsoon climates in three of South Asia’s rapidly growing cities. This will be undertaken at a time when climate change and urban development conspire to produce unlikely futures for urban survival. Extreme weather events, all attributed to the monsoon’s capricious nature, are resulting in increasing frequency in water shortages, power failures, floods, out-breaks of disease, damage to property and loss of life. In responding to these events, the project will challenge the dominant view of the monsoon as a natural meteorological system outside of and distinct from society. Instead it will propose that the monsoon is a co-production of physical and social dynamics entangled within historic lived environments that can be analyzed, worked with, shaped and changed. To do so, an unconventional interdisciplinary team will develop a novel research methodology around the new operative concept of ‘monsoon assemblages.’ This will bring together the spatial design disciplines with the environmental humanities to advance research of lived environments as indivisibly natural, social and political and to propose models for intervening in them through design. The project aims to shift conceptions and understandings of the monsoon as a natural meteorological system; to deliver a ground breaking new approach to the design of cities by treating the monsoon as an organizing principle of urban life, not an external threat; to assess the potential impact of this approach for urban policy, planning and infrastructure investment; to assess the new political, theoretical and aesthetic agendas for the spatial design disciplines and the environmental humanities this opens up; and to engage critically with the climate change adaption paradigm through the innovative idea of climate co-production.";1497212;1497212;ERC-2015-STG;/ERC-STG;THE UNIVERSITY OF WESTMINSTER LBG;UK;;;;1;0;0;2;0;0 201678;712754;BEST;SIGNED;H2020-EU.1.3.4.;MSCA-COFUND-2015-FP;H2020;Postdoctoral Programme in Bioengineering Excellence Scientific Training;2017-02-01;2022-01-31;;"The Institute of Bioengineering of Catalonia (IBEC) is a leading-edge multidisciplinary research centre based in Barcelona that conducts excellent interdisciplinary research at the frontiers of engineering and life sciences in order to generate new knowledge that helps to enhance quality of life, improve health and create wealth. It is currently located in Barcelona Science Park, has facilities covering 2,500 sq. m., 18 research groups and a team of researchers and support services made up of 250 people from more than 20 different countries. The Barcelona Science Park offers a highly stimulating biomedical environment where IBEC can work in close cooperation with both public and private organisations. IBEC is one of the 20 research institutions labelled as a Severo Ochoa Research Centre, which recognizes excellence at the highest international level in terms of research, training, human resources, outreach and technology transfer. Since 2015, IBEC is awarded with the ‘Human Resources Excellence in Research’. IBEC has decided to launch the Programme in Bioengineering Excellence Scientific Training (BEST). The programme aims to attracting international experienced researchers in the areas of Nanomedicine, Cell Engineering and ICT for Health, the three research Flagships at IBEC. BEST Postdoctoral Programme will provide exceptional training opportunities for up to 24 (in 2 calls of 12 positions per call) high-potential fellows, with a 2-year contract at IBEC and funded interdisciplinary and intersectoral placements at world-class research centres, hospitals and companies within IBECs global network of collaborating institutions, which so far includes 16 academic institutions, 5 hospitals and 11 companies from 4 different continents. BEST represents a unique opportunity to widen career perspectives of BEST fellows and create a talented workforce in biomedical engineering, an exciting multidisciplinary field that is called to transform healthcare in the XXI Century.";3398400;1699200;H2020-MSCA-COFUND-2015;/MSCA-COFUND-FP;FUNDACIO INSTITUT DE BIOENGINYERIA DE CATALUNYA;ES;;;;1;0;0;2;0;0 200985;701852;BIDMAG;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Biological detection with functionalized Magnetic Sensor;2016-05-01;2019-02-17;;"The key goals of the BIDMAG project are: a) the training of a talented experienced researcher, Dr Lopes, in the fast growing field of science, technology and industrial applications of magnetic biosensors, where the host has a critical knowledge and expertise; and, b) design, development and optimisation of cost-efficient smart hybrid surfaces onto magnetic substrates, able to present magnetic response for detecting bacteria. The interdisciplinary training program includes magnetic materials surface modification, fabrication, modelling, characterisation of Magnetoelastic Resonators (MER), surface biofunctionalisation and detection of the biological parameters, which will enhance and broaden her expertise and increase her exposure to both academic and industrial collaborations. She is a talented researcher who has gained much expertise in interdisciplinary area of electroactive polymer composites during her postgraduate career. This background is invaluable for applying in preparation and characterisation techniques of smart materials. To further her career in magnetic biosensors Dr Lopes needs to gain expertise in functional materials and magnetic characterisation, fields in which BCMaterials has a world-recognised expertise. Additionally, through secondments at academic and industrial co-hosts, at ACREO and VAC, respectively, she will gain additional training in: industrial production of MER and Optimization of compact and commercial MER interrogation systems.The impact of the project will be multidisciplinary, since it has applications ranging from environmental monitorization and food quality control to fast medical diagnostics. Besides, to further boost her career, Dr Lopes needs to increase her supervision and teaching experience, gain project and intellectual property management expertise, research funding and proposal writing skills. Multidisciplinary activities will assist her in acquiring necessary competences and reaching professional maturity.";158121,6;158121,6;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;FUNDACION BCMATERIALS - BASQUE CENTRE FOR MATERIALS, APPLICATIONS AND NANOSTRUCTURES;ES;;;;1;0;0;2;0;0 195572;658244;PEMETH;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Planning and Evaluation Methodologies for Mental Healthcare Buildings;2015-06-01;2017-05-31;;The study of psychiatric facilities is major for the care of vulnerable people. It is central to the study of therapeutic environment for mental health, great value for understanding mental illness and the psychosocial impact of the built environment and formulating interdisciplinary relations between architecture and health. In Europe, about 20% of the burden of disease relates to mental illness. With low diagnostic and low medical treatment accuracy factor, environment is key for quality of care and patients’ social re-integration. The key questions of this proposal are: (i) how the mechanisms of the environment influence the personal and social milieu of psychiatric space, and (ii) how the environmental needs of the mentally ill are met by wards. Work in other healthcare settings has shed some light on the first, yet little is known about the second. For these, the researcher aims to exploit the scientific tools of architectural morphology (Space Syntax) and juxtapose them with a patient-focused, model for the evaluation of psychiatric environment (the SCP model), to investigate environment in an integrated way. The research will be comparative of two methodologies and will involve facilities in the community as case studies for its physical locus. Those will be examined for their spatial qualities. The findings could set the framework for a model for evidence-based healthcare architecture to serve as design and evaluation tool, immediately accessible to architects and stakeholders. The final product will be design methods and guidelines for healthcare architecture and in particular for community psychiatric facilities immediately accessible to architects. The research is expandable, when environment is important in prevention and care strengthening the area between healthcare from one side and architecture on the other. However, the largest contribution is in architecture, a sector of great potential, yet in need of more interdisciplinary connections.;195454,8;195454,8;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;UNIVERSITY COLLEGE LONDON;UK;;;;1;0;0;2;0;0 193920;642514;TRACKWAY;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2014-EID;H2020;Training of Innovative, Creative and Entrepreneurial Researchers in Waterborne Dispersed Polymers;2015-01-01;2018-12-31;;TRACKWAY aims at training the next generation of creative, entrepreneurial and innovative researchers combining projects at the frontline of the research in functional dispersed polymers with interdisciplinary training in transferable and specialized skills. Based on the synergetic collaboration between BASF, a leading industry in dispersed polymers and University of the Basque Country, a reputed academic institution in the field, the research programme faces the challenge of innovation aiming at creating new waterborne dispersed polymers with new functionalities and lower environmental impact. In particular, it aims at developing intrinsically autonomous self-healing coatings, waterborne adhesives with controlled temperature responsiveness, and non-leaching exterior coatings that will avoid the long-term environmental concern caused by the leaching of surfactants from roofs and facades. The research program is complemented with training in basic and industrially-relevant transferable skills and with exposure of the young researchers to different environments and ways of thinking beyond the consortium. The young researchers trained in this interdisciplinary and intersectorial programme will be able to face the challenge of converting knowledge into useful, marketable and sustainable products, which will make them highly valuable by the large EU industry in this field as well as for many other industrial sectors and academia.;745634,16;745634,16;H2020-MSCA-ITN-2014;/MSCA-ITN-EID;UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA;ES;BASF SE;DE;;1;0;0;2;0;0 194387;645763;INCAS;SIGNED;H2020-EU.1.3.3.;MSCA-RISE-2014;H2020;Understanding institutional change in Asia: a comparative perspective with Europe;2015-06-01;2019-05-31;;"The project INCAS aims at creating a top-level research and advanced training network on institutional change in Asia, in comparative perspective with Europe. The coordinator, Ecole des Hautes Etudes en Sciences Sociales (France), promotes this network together with Oxford University, Freie Universität Berlin, in collaboration with Waseda University (Japan). The partners have chosen Japan as a reference point because of its comparability with Europe as shown by previous studies, its historical influence on development and further institutional changes in Asia, and the expertise accumulated within our research team. Our approach, which refers to the literature on comparative capitalism, is fundamentally interdisciplinary by nature, as it aims at gathering economists, economic historians, political economy specialists, sociologists, and lawyers, who are specialized in various fields such as finance, labor economics and sociology, Asian studies, etc. Our major aim is to propose a new theory of institutional change that better takes into account diverse dimensions that have been overlooked by previous attempts such as: the historical experience of institutional change in Asia that went hand in hand with growth and development; the relations between (especially financial) liberalization and corporate diversity; the interaction between political economy, socio-economic and legal variables. It requires not only the interdisciplinary approach described above but also an empirical investigation that mobilizes a database for corporate characteristics. Each institutional member of INCAS has developed its own research strategy on a similar object (institutional change in Asia and Europe) and the goal of this project is to organize a knowledge transfer within our team (and later outside the research team) in order to build a comprehensive research program.";778500;778500;H2020-MSCA-RISE-2014;/MSCA-RISE;ECOLE DES HAUTES ETUDES EN SCIENCES SOCIALES;FR;"THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;FREIE UNIVERSITAET BERLIN";"UK;DE";;1;0;0;2;0;0 195381;657039;Repower Democracy;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Repower Democracy: How grassroots energy initiatives are changing the face of democracy in Europe;2015-05-04;2017-05-03;;When in 2013, a multinational energy corporation started to set up a drilling site in ¯urawlów – a village in eastern Poland– residents sprang into action to protest the plans to use fracking (an unconventional method of shale gas extraction). Like social movements in the recent global wave of protest (such as Occupy, Indignados), they engaged in egalitarian organising. Finally, the corporation abandoned the village but the residents' activism did not end. Like the citizens in ¯urawlów, similar anti-fracking groups in Europe are working on initiatives to build democratically-run renewable energy solutions. This project investigates the potential of such groups for a repowering of democracy, i.e. a reformulation of democratic models and a reorganisation of energy production along more egalitarian lines. The main objectives of the research are: (1) to investigate the forms of politicisation and imaginaries of egalitarianism in Polish and British communities and (2) to build interdisciplinary, inter-sectoral collaborations and draw up research-led strategies for local and systemic social innovation in the field of democratic self-organisation of energy initiatives. I will employ ethnographic research, local historical and rural sociological investigation to identify best democratic practice models of the communities. Through participatory action research and together with research participants we will develop and implement a framework for the assessment of community's energy potential. The projects' interdisciplinary nature contributes to critical enquiry into the possibilities of more democratic futures and their interrelationship with transitions of energy systems. The core focus is on the local dynamics of grassroots organising and its intersections with (inter)national structures. The overarching aim is to repower democracy in Europe– to help its citizens to be actively engaged in democratic processes by taking responsibility for tackling major societal challenges.;196400,4;196400,4;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;UNIVERSITETET I BERGEN;NO;;;;1;0;0;2;0;0 205430;721281;BBDiag;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2016;H2020;Blood Biomarker-based Diagnostic Tools for Early Stage Alzheimer’s Disease;2017-01-01;2020-12-31;;Alzheimer’s disease (AD) affects more than 7 million people in Europe and this figure is expected to double every 20 years. Despite intensive efforts, no disease-modifying treatments or preventive strategies are available. The lack of specific, sensitive and minimally invasive diagnostics to identify people with early-stage AD to be included in clinical drug intervention trials is among the main reasons for many notable trial failures. The main challenges in developing the required diagnostics are identification of AD biomarkers and development of their detection techniques. The complex and interdisciplinary nature of the research underlines the need for innovative training of a new generation of researchers in the field. BBDiag responds to such a need and establishes a much-needed ETN for blood based early-AD diagnostics to address these challenges. It brings together leading academic and industrial experts from five major consortia in Europe and uses their synergies to build a triple-i research & training platform with the required multidisciplinary expertise and cutting-edge technologies. BBDiag Fellows will be trained under the Vitae Researcher Development Framework innovatively combined with the BBDiag platform for gaining interdisciplinary scientific and transferable skills as well as personal quality, creative thinking and business mind-set. The ETN has a highly innovative research programme for the discovery of AD biomarkers, development of novel biosensing techniques and point of care tools, and for technological exploitation of the diagnostics. These advances will strongly support improved care provision and development of disease-modifying treatments and preventive strategies for AD patients. More importantly, BBDiag will deliver its first generation of 13 highly-skilled, creative and entrepreneurial Fellows, setting them on a path to successful careers in academia or industry to ensure that the medical and societal challenges imposed by AD are met.;3465708,24;3465708,24;H2020-MSCA-ITN-2016;/MSCA-ITN-ETN;UNIVERSITY OF PLYMOUTH;UK;"SWANSEA UNIVERSITY;ISTITUTO DI RICERCHE FARMACOLOGICHE MARIO NEGRI;ADVANCED MEDICAL PROJECTS SOCIEDAD LIMITADA;UNIVERSITATSMEDIZIN ROSTOCK;PROGNOMICS LTD;DANMARKS TEKNISKE UNIVERSITET;CENTRO DE INVESTIGACION BIOMEDICA EN RED ENFERMEDADES NEURODEGENERATIVAS;NORDIC BIOSCIENCE A/S;UNIVERSITA DEGLI STUDI DI ROMA LA SAPIENZA;NORDIC BIOSCIENCE COMPOUND DEVELOPMENT A/S";"UK;IT;ES;DE;DK";;1;0;0;2;0;0 206965;715626;LatinNow;SIGNED;H2020-EU.1.1.;ERC-2016-STG;H2020;The Latinization of the North-western Roman Provinces: Sociolinguistics, Epigraphy and Archaeology;2017-03-01;2022-02-28;;"This is an interdisciplinary project linking sociolinguistics, archaeology and ancient cultural history. Dramatic changes occurred linguistically in the north-western Roman Empire: a patchwork of local languages which existed in the Iron Age had been all but replaced by Latin as the dominant language by the end of the imperial period. Precisely how, when and why this change occurred, and how it relates to other social phenomena, remains an underexplored topic central to the Roman world and requires investigation which is only possible through an analysis cutting across provincial boundaries, those between the Iron Age, Roman and early medieval periods, and reaching beyond Classics to modern sociolinguistics and Germanic, Celtic and Palaeo-hispanic studies. LatinNow bridges this gap in our knowledge by employing an approach which exploits both epigraphic and archaeological material (writing and writing equipment) and situates the phenomena of Latinization, literacy, bi- and multilingualism within broader social developments. Drawing together the developing strands of sociolinguistics, bilingualism studies, digital epigraphy, and small finds archaeological investigation into an integrated methodology brings a fresh perspective, founded on empirical data and supported by evolving technologies (GIS, EpiDoc, RTI). The interdisciplinary approach and analytical rigour, promoted in 3 research volumes, project GIS, RIBOnline, conference and workshops, will encourage the extension of this methodology. The creation of a centre of excellence for digital epigraphy at the University of Nottingham and the touring exhibition, which will disseminate research and skills across the ERA, will spread the competences and knowledge necessary for the implementation of this new research across the Roman world and beyond. LatinNow confronts thorny, large-scale socio-cultural issues and will contribute to an appreciation of the construction of our diverse European heritage.";1496272;1496272;ERC-2016-STG;/ERC-STG;THE UNIVERSITY OF NOTTINGHAM;UK;;;;1;0;0;2;0;0 201154;703526;FLAMENCO;CLOSED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;FLAgellated MicroswimmErs’ locomotioN in Confined flOws;2016-08-01;2018-07-31;;The ultimate goal of this Fellowship, entitled “FLAgellated MicroswimmErs’ locomotioN in Confined flOws” (FLAMENCO) is to train a talented researcher in computational modelling of micro-swimming. A variety of interdisciplinary training activities are planned with the purpose of transferring the cutting-edge knowledge in theoretical, computational and experimental microswimmer dynamics. The specialist training will be provided by Queen Mary University (Engineering Department), which, through this action, will establish a long-term collaboration network with the University of Warwick (Physics Department), the International School for Advanced Studies (SISSA) in Trieste, and the University of Padova (Department of Medicine). The interdisciplinarity of the institutes involved will allow the experienced researcher (ER) to appreciate the potential of the acquired knowledge for tackling problems relevant to field as diverse as engineering, biology, reproductive medicine and medical diagnostic. The innovation of this program consists in aiming at the quantitative understanding and mathematical modelling of phenomena that can mainly be described qualitatively at present. The outcomes will potentially provide the tools and body of knowledge for controlling and manipulating microswimmers near the solid surfaces. The intermediate objectives (deliverables) of this research project are (1) the derivation of a validated micro-swimmer/ surface interaction model, (2) a validated swimming swarm model at high-fidelity and ‘low-order’ level, (3) recommendations for separating swimming spermatozoa based on their motility.;183454,8;183454,8;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;QUEEN MARY UNIVERSITY OF LONDON;UK;;;;1;0;0;2;0;0 199936;691051;CARDIALLY;SIGNED;H2020-EU.1.3.3.;MSCA-RISE-2015;H2020;Capturing and quantitative analysis of multi-scale multi-channel diagnostic data.;2015-11-01;2019-10-31;;We are proposing a four-year programme of knowledge transfer between Aston University (ASTON, UK), Universita Degli Studi Di Brescia (UNIBS, Italy), Diasens (Diasens, Serbia), and Novosibirsk State University (NSU, Russia). The aim of our interdisciplinary proposal is to bring together the unique expertise of participants to solve the important and challenging problem of heart failure prediction and diagnostic. Our transformative approach combines advanced methods of complex data analysis and novel diagnostic technologies to prevent highly damaging consequences of this deadly and disabling disease. Strong interdisciplinary nature of the project and a balance of industrial applications and fundamental science ensure a wide range of skill and knowledge transfer within the consortium. Working in close collaboration with our SME partner will allow early career researchers to gain an invaluable experience in bringing research to real life applications and to broaden their future career choices. The research has significant potential for life-changing applications in cardiology, especially relevant to adult and aging population. Solution to this problem will help to cut costs in European health care systems and improve quality of life of millions of people.;234000;234000;H2020-MSCA-RISE-2015;/MSCA-RISE;ASTON UNIVERSITY;UK;"DIASENS DOO BEOGRAD;UNIVERSITA DEGLI STUDI DI BRESCIA";"RS;IT";;1;0;0;2;0;0 199192;690900;DATA4WATER;SIGNED;H2020-EU.4.b.;H2020-TWINN-2015;H2020;Excellence in Smart Data and Services for Supporting Water Management;2016-01-01;2018-12-31;;"The objective is to enhance the S&T abilities in the field of smart, data driven e-services in water management, with focus on the widening organization. The complexity of research related to water management is extremely high and requires deep expertise in several ICT-related research domains. The dynamics of water and the role of humans in the water cycle are not well understood largely because environmental and socio-economic analyses are still performed separately. The specific objectives are: Enhance the science and technology capacity of the participating institutions; Raise staff’s research profile as well as the one of the institutions involved; Contribute to the Smart Specialisation Strategy; Contribute to the development of a new, interdisciplinary research domain. Main activities in the project are: organization of workshops, summer schools; exchange and training of researchers; develop a roadmap for the UPB, aligned with the partners’ research agendas in the area of IT for water management; development of a knowledge transfer and remote training system, and inclusion of UTB team in an operational research network. The research quality system will be set up, based on the Composite indicator of Research Excellence. The project will also help to raise staff’s research profile. The scientific strategy of the UPB team will be oriented towards inter/trans-disciplinary and practical applicability, valorization and impact in water management, which also fits to the Smart Specialization Strategy of Romania. The main expected impact is the increase of publications number with high visibility, and the creation of an active network with relevant stakeholders. The consortium was constituted so that it is representative for the research topic, that has a strong interdisciplinary character, with main focus on information technology. The project consortium consists of two leading research partners in the field of IT and a water management leading research partner.";999493,75;999493,75;H2020-TWINN-2015;/CSA;UNIVERSITATEA POLITEHNICA DIN BUCURESTI;RO;"STICHTING IHE DELFT INSTITUTE FOR WATER EDUCATION;FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.;UNIVERSITA' DEGLI STUDI DI MILANO-BICOCCA";"NL;DE;IT";;1;0;0;2;0;0 198267;675020;NoNoMeCat;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2015-ETN;H2020;Non-Noble Metal Catalysis - NoNoMeCat;2016-01-01;2019-12-31;;Transition metal catalysts are formidable tools towards greener chemistry, allowing for low-waste, energy-efficient, and selective reactions. However, the noble metals (Ru, Os, Rh, Ir, Pd, Pt) that are currently most common in homogeneous catalysts suffer from high toxicity and environmental impact in addition to their scarcity and ensuing high cost. First-row metals (Mn, Fe, Co, Ni, Cu) are emerging as environmentally benign alternatives, but to this day rarely equal the performance of their noble counterparts. The NoNoMeCat network aims at providing excellent and structured interdisciplinary training to a generation of young researchers in the field of Non-Noble Metal homogeneous Catalysis who will push the boundaries of the field in terms of catalyst stability, selectivity, mechanistic understanding, and scalability. These challenges are addressed in three areas of high fundamental and practical significance: the oxidation of hydrocarbons, the formation of new C-X bonds (C-C, C-N) bonds through cross-coupling reactions, and clean energy production. NoNoMeCat will enrol 14 Early Stage Researchers (ESRs) who will receive structured training in experimental and theoretical aspects of non-noble metal chemistry as well as transferable skills such as research integrity, scientific communication and public outreach. Tight integration of non-academic partners will expose all ESRs to aspects of both fundamental interdisciplinary research and industrial application, paving the way for long-standing intersectorial collaborations.;3318634,08;3318634,08;H2020-MSCA-ITN-2015;/MSCA-ITN-ETN;UNIVERSITEIT UTRECHT;NL;"UNIVERSITAT DE GIRONA;UNIVERSITE DE BRETAGNE OCCIDENTALE;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;UNIVERSITAET BERN;DSM CHEMICAL TECHNOLOGY R & D BV;LEIBNIZ - INSTITUT FUR KATALYSE EV AN DER UNIVERSITAT ROSTOCK;ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE;KATHOLIEKE UNIVERSITEIT LEUVEN";"ES;FR;DE;CH;NL;BE";;1;0;0;2;0;0 198321;676154;ArchSci2020;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2015-EJD;H2020;Archaeology on the Edge: Northern Europe and the Circumpolar World;2016-04-01;2020-03-31;;"ArchSci2020 will provide structured state-of-the-art doctoral training to the next generation of archaeologists and biomolecular scientists forging a new generation of biomolecular archaeologists. Few other academic disciplines have been so transformed in the last decade as Archaeology. ArchSci2020 meet the need of a new generation of researchers. International, intersectoral and interdisciplinary training will equip its early-stage researchers (ESRs) with specific research-related and transferable skills, in order to provide enhanced career prospects across academia, industry and the third sector. The proposed ArchSci2020 network will bring together four leading research clusters each with complementary expertise to deliver an integrated, flexible training package that will provide a sound basis for academic independence and preparation for vocations in the archaeology, heritage and beyond. ArchSci2020 will combine (i) a common purpose, (ii) an unconditional commitment to the student experience, (iii) a pro-active stance towards international, inter-institutional research support and interdisciplinary study, (iv) a simple but effective management structure provided by a Management Team, Supervisory Committee and the Work Package leaders, (v) and an established academic infrastructure and reputation. Key features of ArchSci2020: 1. ArchSci2020 will create a multidisciplinary training environment that brings together archaeologists, biologists, mathematicians, analytical chemists, and policy experts around an archaeological hub. 2. ArchSci2020 priorities and cross-cutting training themes align closely with ‘Grand Challenges’ across its themes of Health, Diet, and Environment and incorporates the important current skills and future training needs in archaeological science. 3. Each participating institution will make a unique and distinct contribution to the experience of Early Stage Researchers (ESRs) in a partnership formed from existing strong environments.";4074239,16;4074239,16;H2020-MSCA-ITN-2015;/MSCA-ITN-EJD;UNIVERSITY OF YORK;UK;"KOBENHAVNS UNIVERSITET;RIJKSUNIVERSITEIT GRONINGEN;STOCKHOLMS UNIVERSITET";"DK;NL;SE";;1;0;0;2;0;0 198317;676063;DCOMM;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2015-ETN;H2020;Deictic Communication - A Multidisciplinary Training;2016-02-01;2020-01-31;;Deictic communication is fundamental to understanding communication in both typical and atypical populations, and forms the key connection between language and objects/locations in the world. It is therefore critical to understanding human-human interaction, and human-system interaction in a range of technology applications – from mobile phones to cognitive robotics – and to the enhancement of clinical and educational interventions with typical and atypical populations. This ETN will train the next generation of scientists in the full range of multidisciplinary and cross-sectorial methods necessary to make significant progress in understanding deictic communication, with direct synergies between basic research and application. Training is structured around two interdisciplinary research themes – Understanding Deictic Communication and Deictic Communication in Application – both involving extensive and systematic co-supervision and collaboration across sites with key interplay between academic and nonacademic beneficiaries and partners. In turn we expect that a range of applications will be enhanced with increased usability, with associated societal and economic benefit. The training of the cohort of ESR fellows is based on innovative PhD training approaches, providing not only training in interdisciplinary methods, but also employing peer-assisted methods and the latest in educational innovation. This will produce a cohort of highly skilled researchers who will be highly employable given the potential contribution they will make to future research and innovation in the public and private sectors.;3460823,28;3460823,28;H2020-MSCA-ITN-2015;/MSCA-ITN-ETN;UNIVERSITY OF EAST ANGLIA;UK;"AARHUS UNIVERSITET;WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER;QUALISYS AB;DANIELI TELEROBOT LABS S.R.L.;UNIVERSITY OF PLYMOUTH;FRIEDRICH-SCHILLER-UNIVERSITAT JENA;CONSIGLIO NAZIONALE DELLE RICERCHE;EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH;UNIVERSITAT DE LES ILLES BALEARS;NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU";"DK;DE;SE;IT;UK;CH;ES;NO";;1;0;0;2;0;0 198606;646612;Eurasia3angle;SIGNED;H2020-EU.1.1.;ERC-CoG-2014;H2020;Millet and beans, language and genes. The origin and dispersal of the Transeurasian family.;2015-09-01;2020-08-31;;"'The question about the origin and dispersal of the Transeurasian languages (i.e. Japonic, Koreanic, Tungusic, Mongolic and Turkic) is one of the most disputed issues in linguistic history. Eurasia3angle will address this question from an interdisciplinary perspective. My key objective is to effectively synthesize linguistic, archaeological and genetic evidence in a single approach, for which I use the term 'triangulation'. To this end, my project will bring together a highly qualified interdisciplinary team of doctoral and postdoctoral researchers along with world-eminent experts, who will focus on testing the Farming/Language Dispersal Hypothesis for the Transeurasian languages. The FLDH attributes the dispersal of some of the world's major language families to the adoption of agriculture and subsequent population expansion, whereby the language of new farmers displaced that of preexisting hunter gatherers. In contrast to its application to the major language families in East Asia, the FLDH has not been tested yet for the Transeurasian languages. My research team will specifically investigate the hypothesis that the Transeurasian languages derive from a homeland in South Manchuria and that their early dispersal should be associated with the spread of cultivation of millet and beans. For this purpose, we will use advanced techniques recently introduced to the individual disciplines, such as the application of phylogenetic methods to linguistic classification, a focus on derivational morphology in the reconstruction of subsistence-related language, a matrix-based comparison of archaeological cultures and a model-based approach applied to genome-wide autosomal data. Converging these partial perspectives into a more holistic understanding of what really happened in the past is quite a challenge. However, if successful, this research will be a break-through in the investigation of human prehistory in general and in the long-standing Transeurasian debate in particular. '";2000000;2000000;ERC-2014-CoG;/ERC-COG;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;DE;;;;1;0;0;2;0;0 193924;642563;COSMOS;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2014-EJD;H2020;Complex Oscillatory Systems: Modeling and Analysis;2015-01-01;2019-08-31;;Many natural and artificial systems are often composed of oscillatory elements which, besides evolving according to their own non-trivial internal dynamics, mutually interact. As a result, many temporal and spatial scales are typically present, often accompanied by the spontaneous emergence of collective properties. Altogether, such features make the task of understanding the resulting evolution a challenging interdisciplinary problem. Zero-knowledge methods do generally require too large amount of data to allow drawing meaningful conclusions. In order to overcome this limitation, it is necessary to add skilful hypotheses about the structure of the underlying model and, thereby, on the relevant variables. This task is often tackled in an ad hoc way and the approach is based rather on personal preferences than on objective elements. The goal of this project is to fill the gap, by developing a general and coherent set of tools for the system identification and control, as well as to improve our ability to make predictions. The task will be pursued by combining top-down with bottom-up approaches which will be used to identify the most appropriate variables. Such analysis will be integrated by performing suitable case studies and mutually validating the various techniques to test the correctness of the underlying assumptions (both in the context of theoretical models as well as in experimental time series, such as physiological and neural data). A user-friendly software package will be ultimately developed to make the methods accessible to a broad set of potential users, including those with minimal theoretical competences. Furthermore, we will train a new generation of scientists able to implement a broad range of interdisciplinary approaches to the multivariate time signals that may be generated by the evolution of complex systems.;3877488,12;3877488,12;H2020-MSCA-ITN-2014;/MSCA-ITN-EJD;UNIVERSITAET POTSDAM;DE;"UNIVERSIDAD POMPEU FABRA;THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN;MEDIZINISCHE UNIVERSITAT GRAZ;STICHTING VU;UNIVERSITA DEGLI STUDI DI FIRENZE;LANCASTER UNIVERSITY;FAKULTETA ZA INFORMACIJSKE STUDIJE V NOVEM MESTU";"ES;UK;AT;NL;IT;SI";;1;0;0;2;0;0 193960;642890;TheLink;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2014-ETN;H2020;European Training Network to Accelerate the Development Chain of Nanostructured Polymers;2014-11-01;2018-10-31;;"Research and training in TheLink spans the material development chain for nanostructured polymers. These materials, including phase separated polymers and composites, are attracting scientific and industrial interest due to the outstanding properties and functionalities that can be achieved. However, to exploit the potential of these materials an in-depth understanding of the relationship between nano/micro structures and macro-level properties is required. TheLink aims to generate this knowledge on an interdisciplinary basis combining simulation, characterisation and processing. The recruited fellows will take nanomaterial development beyond “trial and error” towards a knowledge-based and industrially feasible approach. Three case studies (phase separated polymers and composites, separation membranes and self-diagnosing polymers) will be used to guide the research and to demonstrate the project developments. Careful attention will also be paid to broader market requirements and standardisation. High-quality individualised training in scientific and transferable skills, and a structured network program of training units, will provide the fellows with unique interdisciplinary competence in simulation, characterisation and processing, and move them from theoretical investigations towards industrial application and entrepreneurship. The active involvement of industrial partners, secondments in applied research and industry and a strong research and training emphasis on market requirements will furthermore provide them with the intersectoral experience needed for a career in the development of nanostructured polymers.";3794898,96;3794898,96;H2020-MSCA-ITN-2014;/MSCA-ITN-ETN;FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.;DE;"UNIVERSIDADE DO MINHO;PROMOLDING BV;COVESTRO DEUTSCHLAND AG;GVS S.P.A.;AVANZARE INNOVACION TECNOLOGICA SL;IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE;UNIVERSITEIT TWENTE;FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS;KARLSRUHER INSTITUT FUER TECHNOLOGIE";"PT;NL;DE;IT;ES;UK;EL";;1;0;0;2;0;0 203227;679528;POSTDATA;SIGNED;H2020-EU.1.1.;ERC-StG-2015;H2020;Poetry Standardization and Linked Open Data;2016-05-01;2021-04-30;;"This project aims at bridging the digital gap among traditional cultural assets and the growing world of data. It is focused on poetry analysis, classification and publication, applying Digital Humanities methods of academic analysis -such as XML-TEI encoding- in order to look for standardization. Interoperability problems between the different poetry collections are solved by using semantic web technologies to link and publish literary datasets in a structured way in the linked data cloud. The advantages of making poetry available online as machine-readable linked data are threefold: first, the academic community will have an accessible digital platform to work with poetic corpora and to contribute to its enrichment with their own texts; second, this way of encoding and standardizing poetic information will be a guarantee of preservation for poems published only in old books or even transmitted orally, as texts will be digitized and stored as XML files; third: datasets and corpora will be available and open access to be used by the community for other purposes, such as education, cultural diffusion or entertainment. To accomplish such a ground-breaking approach, I have a hybrid profile, combining a strong philological background, specialized in poetry and metrics, with a deep knowledge of Digital Humanities proven by my leadership and experience in interdisciplinary projects. Since 2011, I am the Principal Investigator of the first Digital Repertoire of Medieval Spanish Poetry (ReMetCa), an innovative project that combines traditional metrical analysis with digital text encoding, and since 2014 I am the Academic Director of LINHD, The Digital Humanities Innovation Lab created at UNED as a research interdisciplinary centre.";1131413;1131413;ERC-2015-STG;/ERC-STG;INDRA SISTEMAS SA;ES;UNIVERSIDAD NACIONAL DE EDUCACION A DISTANCIA;ES;;1;0;0;2;0;0 199939;691061;nanoBAT;SIGNED;H2020-EU.1.3.3.;MSCA-RISE-2015;H2020;Enhanced brown adipose tissue activity using nanotechnology approaches;2016-02-01;2020-01-31;;The use of nanotechnology and nano-materials in biological applications is being widely explored and is considered a valuable approach to ameliorate human wellbeing. Specifically, nanoparticles and carbon nanotubes are of great scientific interest as they are currently used clinically as delivery systems for a wide range of drugs. An interdisciplinary approach that considers knowledge in chemistry, nano-materials, toxicology, physiology, molecular biology is vital for the progress of these devices and for the development of new procedures to create a novel market-ready prototype to boost human metabolism, fighting obesity and cardio-metabolic disease. An inter-sectoral approach is also required to put together Academic’s technical capabilities and facilities to conduct R&D activities with SMEs’ business expertise and viable supply chain to develop the prototype post project and to exploit the product in the market. Therefore, two academic (VUB and UniPD) and three industrial (INOC, IMED, ARTIA) European participants will create an interdisciplinary and inter-sectoral co-operation (nanoBAT) to design and construct a novel nanostructured delivery-L-menthol system prototype for brown adipose tissue activation. During its four years duration, nanoBAT aims to achieve research and innovation objectives via staff exchanges of experienced and early-stage researchers throughout a series of activities like: networking, research and training, workshop, innovation, dissemination, and outreach.;864000;864000;H2020-MSCA-RISE-2015;/MSCA-RISE;VRIJE UNIVERSITEIT BRUSSEL;BE;"IMEDICA SA;UNIVERSITA DEGLI STUDI DI PADOVA;CREATIVE NANO PC;INOCURE SRO";"RO;IT;EL;CZ";;1;0;0;2;0;0 221663;847675;oLife;SIGNED;H2020-EU.1.3.4.;MSCA-COFUND-2018;H2020;The origin and evolution of Life in the universe;2019-04-01;2024-03-31;;The origin and evolution of life remains one of the biggest puzzles for humankind. We still do not know where we come from, nor do we know what the future will bring. While at the disciplinary level some aspects of the origin of life question have been unravelled, the answers obtained thus far are fragmentary and far from complete. We are convinced that an unconventional trans-disciplinary approach is needed for making substantial progress. The oLife FP brings together a wide range of disciplines ranging from molecular biology to astrophysics, and from evolutionary ecology to biochemistry. This ground-breaking broad approach will undoubtedly lead to major new insights and perhaps even to a real breakthrough in the origin of life question. This COFUND initiative is part of a national interdisciplinary research effort, involving 300 scientists from top research institutions in the Netherlands, who are joining forces to enhance our understanding of the origin, evolution, distribution and development of life in the universe, with the ultimate goal of developing methods for steering life on a human-dominated planet. Besides pursuing interdisciplinary research on an internationally competitive level, the oLife FP will provide top-level training to junior scientists, who by interacting with researchers from various disciplines and secondments in academia, companies and other non-academic institutions will be ideally prepared for a career inside and outside of academia.;3972240;1986120;H2020-MSCA-COFUND-2018;/MSCA-COFUND-FP;RIJKSUNIVERSITEIT GRONINGEN;NL;;;;1;0;0;2;0;0 221603;840992;ArCarib;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Archaeology of Informal Maritime Commerce in the Colonial Caribbean;2019-04-01;2021-03-31;;Informal commerce thrived for more than two centuries between the Dutch islands of Aruba, Curaçao, and Bonaire (ABC islands) and Spanish colonial Venezuela, seducing a diversity of regional trans-imperial seafarers and mobilizing vital commodities. Indispensable European ceramics were traded to the mainland chronically neglected by Spanish provisioning fleets, while local Venezuelan ceramics itinerated to the ABC islands to satisfy everyday domestic needs. While much is known about the socioeconomic and political history and impacts of this longstanding commerce, nothing is known of its material dimensions and how the indispensable smuggled ceramics changed or maintained the identities and gender relations of peoples in the colonial societies on the islands and the continent. The central research question of this project is: how did the informal maritime commerce of ceramics in the 17th- and 18th-century South-eastern Caribbean impact the everyday life of communities on the ABC islands and on the Venezuelan coast, particularly their identity formation processes and gender relations? This interdisciplinary historical archaeological project employs my innovative theoretical and methodological framework of assemblages of practice to critically contrast new and existing archaeological, archaeometric, and documentary evidence and answer this central research question. In this first cross-border archaeological study between the ABC islands and Venezuela, I will break new ground revealing how through informal commerce the colonized agentially contributed to the dynamics of continuation and/or change in their communities’ identities and gender relations beyond the restrictive, acculturating, and engendering policies imposed by the colonizer. Through this project I will, therefore, generate completely new knowledge that will advance interdisciplinary understandings of contraband and informal commerce in early-modern colonial contexts and its material dimensions and impacts.;172932,48;172932,48;H2020-MSCA-IF-2018;/MSCA-IF-EF-ST;UNIVERSIDAD POMPEU FABRA;ES;;;;1;0;0;2;0;0 221521;839602;MAYURB;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Understanding ancient urbanism: site planning and unintended consequences of the Classic Maya city as a model;2020-03-01;2023-02-28;;"The main goal of MAYURB is to study ancient urbanism using the Classic Maya Period (250-900 CE) as a model to understand city inception and expansion through time, while considering the diverse actors involved in its planning, use and transformation. The urban fabric of Palenque, Mexico, will be assessed with an interdisciplinary approach that delves into the decision-making process that underlies site planning and considers the limitation imposed by location; in addition, the project ponders the influence of traditions and believes in site selection and religious buildings’ astronomical orientation. While considering the negotiation processes and power relations involved in city inception and growth, MAYURB will explore the unintended consequences of city expansion, such as urban sprawl and sanitation. The project will develop around three main axes: the construction of a GIS platform to join archaeological, architectural and morphological data and to outline the physical reality in which the ancient Maya lived. The spatial analyses performed with GIS will lead the second line of investigation: archaeological excavations at Palenque in areas where it is more likely to uncover infrastructural works and their relative chronology. The third inquiry will explore the extent of authority in site planning and the agency of other urban actors with an interdisciplinary theoretical focus that spans from urban to anthropological theory. The methodological approach and theoretical contribution developed with MAYURB aim at providing a thorough understanding of the planning process and city performance in antiquity, beyond the time period and the geographical location in question. Three unique interchange appointments between UNAM-Mexico, UNIROMA1-Italy and ZRC SAZU-Slovenia at top-level Institutions are planned to fulfill MAYURB’s objectives, while increasing the Experienced Researcher’ skills.";231524,16;231524,16;H2020-MSCA-IF-2018;/MSCA-IF-GF;UNIVERSITA DEGLI STUDI DI ROMA LA SAPIENZA;IT;;;;1;0;0;2;0;0 221701;840894;ME.Tech.NAS;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Metals Technology in North Aegean Societies;2019-05-01;2021-04-30;;The project involves an interdisciplinary study of mining landscapes in northern Greece and archaeological material found therein by employing modern analytical techniques (GIS, archaeometry) in order t? provide quantifiable data on the social, symbolic and economic significance of metal production in the ancient world. The project’s objective is to address three crucial research questions corresponding to different technological breakthroughs: a) the emergence and early development of copper and silver technology within the Late Neolithic/Bronze Age cultural framework (5th-2nd mill. BC), b) the introduction of iron metallurgy associated with increased connectivity between sites of the North Aegean and Anatolia around 1200-700 BC, c) the intensification of mining and extraction of gold and silver during the Archaic and Classical period (700-323 BC), triggered by the establishment of Greek colonies on the Thracian coastline. Its methodology employs interdisciplinary research tools such as archaeological finds recording, field survey, GIS data processing, sampling and archaeometric analysis of finds as well as experimental production of metals using ancient examples. The distinctive feature of this project that will expand research beyond the current state of knowledge will be re-socializing the study of metal production and subsequently to develop new multidisciplinary approaches which will have direct scientific impact on the study of ancient Greek metallurgy and society. Dissemination of the project results will be achieved through publication of scientific articles and a monograph, presentations in international conferences, organisation of a scientific workshop with invited speakers and seminars for students. Workshops for the general public featuring simulation experiments, lectures delivered at science outreach events and a dedicated website will be crucial aspects for communicating the project results more widely.;166320;166320;H2020-MSCA-IF-2018;/MSCA-IF-EF-ST;UNIVERSITE LIBRE DE BRUXELLES;BE;;;;1;0;0;2;0;0 201489;707197;ChroMoLEME;CLOSED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;The Character of Monastic Landscapes in Early Medieval Europe;2016-09-01;2018-08-31;;"The rural monasteries established across Europe in the 6th and 7th centuries played a key role in establishing the church’s centrality to medieval society. Scholars have traditionally accepted the medieval hagiographers’ descriptions of these sites as remote foundations in a wilderness known as the desertum. This interdisciplinary project will contrast these textual sources with an emerging body of archaeological evidence to question the traditional narrative. It will show that monasteries were intimately linked to political and economic networks and often founded in landscapes that were not only inhabited, but quite likely also Christianised. A case study of the 6th-century foundation at Annegray (France) will use an innovative GIS (Geographical Information System) environment to integrate conventional historical and archaeological data with innovative historic landscape character analysis using new remote sensing data. The resulting model will inform comparative study with comparable sites in France, Italy and Switzerland. The Fellow will receive advanced training in Geographic Information Systems (GIS), digital 3D survey and spatial data analysis. He will learn how to integrate conventional sources with remotely-sensed data from geophysical survey, airbone lidar (light detection and ranging), and terrestrial laser scanning (TLS) to create an innovative approach to Historic Landscape Characterisation (HLC). The method pioneered in the project will be broadly applicable to landscape studies of different periods and regions across Europe and beyond. During the project Dr Marron will develop extensive skills in a series of cutting-edge techniques, significantly enhancing his prospects of a successful career in interdisciplinary landscape research.";183454,8;183454,8;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;UNIVERSITY OF NEWCASTLE UPON TYNE;UK;;;;1;0;0;2;0;0 215833;801076;GlobalP3HS;SIGNED;H2020-EU.1.3.4.;MSCA-COFUND-2017;H2020;SSPH+ Global PhD Programme in Public Health Sciences;2018-10-01;2023-09-30;;"The Swiss School of Public Health (SSPH\) - a foundation of eight Swiss universities - seeks to launch a Global PhD Programme in Public Health Sciences (GlobalP3HS) to competitively recruit 50 talented students from around the world to pursue PhD studies in Switzerland. More than 150 SSPH\ faculty members are engaged in interdisciplinary public health sciences and are highly qualified to supervise and train the next generation of public health leaders in both the academic and non-academic sector. Self-driven, critical public health scientists are needed to improve public health on a global scale by providing scientific evidence to shape policies, health systems, life-styles, economies, laws and regulations. Recruitment will be initiated with a global call. Applicants must be eligible for PhD studies in Switzerland and provide a letter of support from a committed supervisor of the SSPH\ community. An International Review Board will score applications on a scale of 0 - 10, based on four dimensions. The Steering Board will select the best candidates (scores ?8). To guarantee the highest standards for PhD studies, students must register in one of the structured PhD programmes led by SSPH\ partners — programmes that adhere to the quality standards of PhD education as defined in the EU Charter for Researchers. Students choose programmes from a wide range of interdisciplinary offers, including health economics, public health, epidemiology, social health sciences, nursing or law. Students must pass at least 18 ECTS, including formal training in transferable skills and research ethics. Furthermore, secondments are offered to allow students to explore non-academic career paths as well. SSPH\’s long-standing experience with highly successful inter-university PhD programmes make SSPH\ well-placed to implement a doctoral programme that builds capacity in public health sciences on a global scale and prepares students for academic as well as non-academic career paths.";9156000;4578000;H2020-MSCA-COFUND-2017;/MSCA-COFUND-DP;STIFTUNG SWISS SCHOOL OF PUBLIC HEALTH PLUS (SSPH);CH;;;;1;0;0;2;0;0 218674;813490;StarT;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2018;H2020;European Training Network to Diagnose, Understand and Treat Stargardt Disease, a Frequent Inherited Blinding Disorder;2018-10-01;2022-09-30;;"StarT will create an interdisciplinary and intersectorial European training network focusing on different aspects of autosomal recessive Stargardt disease (STGD1), a frequent inherited blinding disorder that affects an estimated 925,000 persons worldwide. StarT research aims to uncover the regulation of its disease gene ABCA4 and its missing heritability, in order to develop novel treatments. StarT training will give young researchers unparalleled training opportunities in outstanding vision research groups with unique expertise in omics technologies, bio-informatics, stem cell biology, animal models of disease, and therapeutics, providing each ESR with the necessary competences in state-of-the-art academic and industrial research. STGD1 is due to ABCA4 mutations, however up to 35% of STGD1 cases carries one or no ABCA4 coding mutation. New unconventional classes of ABCA4 mutations were recently discovered by us, the significance of which largely remains elusive. In order to understand the mechanisms triggered by these missing ABCA4 mutations and to design new therapies for STGD1 cases, challenging research questions will be addressed by the integration of unique skills from this network. Early-Stage Researchers will perform cutting edge research using innovative and interdisciplinary approaches: (functional) genomics and transcriptomics, bio-informatics, CRISPR/Cas9 genome editing, generation of stem cell and animal disease models and design of new treatments. The training objectives will be met through academic and industrial training-by-research via individual research projects, secondments, and network-wide training sessions.";3776714,28;3776714,28;H2020-MSCA-ITN-2018;/MSCA-ITN-ETN;UNIVERSITEIT GENT;BE;"NEWCELLS BIOTECH LIMITED;FONDAZIONE TELETHON;THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN;STICHTING KATHOLIEKE UNIVERSITEIT;PROQR THERAPEUTICS NV;UNIVERSITY OF LEEDS;AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS;EBERHARD KARLS UNIVERSITAET TUEBINGEN;UNIVERSITY COLLEGE LONDON";"UK;IT;IE;NL;ES;DE";;1;0;0;2;0;0 218303;812909;CODOBIO;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2018;H2020;Continuous Downstream Processing of Bioproducts;2019-02-01;2023-01-31;;Continuous biomanufacturing is one of the grand challenges of Europe’s bio-industry. It offers a significant opportunity to boost productivity, improve competitiveness and to reduce the environmental footprint. Current progress is impaired by shortage of trained engineers and scientists, who can design and control continuous biomanufacturing processes. This Innovative Training Network (ITN) will focus on addressing the critical gaps in research training to enable advances in continuous downstream processing. An expert consortium of nine industry partners, eight universities, one research organisation, a regulatory institution and a business consultancy has developed a research and training programme to address the most urgent topics in continuous downstream processing. These are: (1) process control and modelling (including economic modelling), (2) miniaturization, scale-up and scale-down of unit operations and (3) process design and development of integrated continuous downstream processes. Furthermore, regulatory framework questions, such as comparability of product quality between batch and continuous processes will be addressed. Adding the regulatory and environmental aspects to the scientific, technological and economic approach, makes our program interdisciplinary, comprehensive and unique. Specific Ph.D. topics for 15 ESRs have been outlined. The presented research and training programme will equip the ESRs with the scientific and important transferable skills, such as IPR, entrepreneurship, data management and innovation management. The consortium’s strong track record in the management of interdisciplinary research and training will ensure effective and timely training of the next generation of leaders able to design innovative continuous facilities of the future for Europe’s bio-industries, ensuring affordability and widened access. Exposure to academic, industry and regulatory sectors will provide the researchers with unparalleled career opportunities.;3991008,24;3991008,24;H2020-MSCA-ITN-2018;/MSCA-ITN-ETN;ACIB GmbH;AT;"NOVASEP PROCESS;LUNDS UNIVERSITET;EVON GMBH;JACOBS UNIVERSITY BREMEN GGMBH;POLITECNICO DI MILANO;UNIVERSITY COLLEGE LONDON;INSTITUTO SUPERIOR TECNICO;TECHNISCHE UNIVERSITEIT DELFT";"FR;SE;AT;DE;IT;UK;PT;NL";;1;0;0;2;0;0 218052;814258;REFLOW;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2018;H2020;Phosphorus REcovery for FertiLisers frOm dairy processing Waste;2019-01-01;2022-12-31;;REFLOW is an interdisciplinary cross-sectoral European Training Network combining world-leading scientists and key stake-holders in dairy processing, fertilizer production and phosphorous recycling with early stage researchers to address important technical and socio-economic challenges associated with the recovery of phosphorous from dairy processing waste water and its recycling into fertilizer products enabling sustainable expansion of the dairy industry in Europe. REFLOW research will (i) mitigate the environmental impact of dairy processing waste on soil and water, (ii) provide safe environmentally sustainable, cost effective closed loop solutions for crop nutrient management (iii) meet the demand for skilled professionals to support the technical, regulatory and commercial development of the market for recycled phosphorous fertilizer products in accordance with the deliverables of the Circular Economy Package. REFLOW will achieve these goals by creating an innovative and entrepreneurial training environment for the next generation of scientists. 13 ESRs will be recruited in a network of 10 beneficiaries and 14 partner organisations who bring complementary expertise and experience of delivering technical solutions, socio-economic modeling, environmental analysis, policy frameworks, high level training and commercial entrepreneurship. Graduating fellows will be equipped with a unique range of relevant interdisciplinary and cross-sectoral skills for careers as independent industrial or academic researchers, entrepreneurs, regulators or agri-environmental specialists. REFLOW will train the Fellows through an integrated and cohesive curriculum of network-wide partner training activities including industrial secondments and embedded commercially driven research projects. The outputs from REFLOW will influence land management practice, the rural bio-economy framework and EU policy goals while significantly progressing the state-of-the-art in Phosphorous recycling.;3469774,68;3469774,68;H2020-MSCA-ITN-2018;/MSCA-ITN-ETN;UNIVERSITY OF LIMERICK;IE;"AARHUS UNIVERSITET;STRANE INNOVATION SAS;FUNDACIO UNIVERSITARIA BALMES;TEAGASC - AGRICULTURE AND FOOD DEVELOPMENT AUTHORITY;INSTITUT POLYTECHNIQUE UNILASALLE;EUROPEAN LANDOWNERS ORGANIZATION;POLITECHNIKA WROCLAWSKA;PRAYON S.A;CHALMERS TEKNISKA HOEGSKOLA AB";"DK;FR;ES;IE;BE;PL;SE";;1;0;0;2;0;0 206841;737432;SAPEA;SIGNED;H2020-EU.3.6.;IBA-EUROPE-ENA-2016;H2020;Science Advice for Policy by European Academies;2016-11-01;2020-10-31;;"The “Science Advice for Policy by European Academies” (SAPEA) project brings together the five European Academy Networks Academia Europaea, ALLEA, EASAC, Euro-CASE and FEAM. Through these networks, the SAPEA project pools the resources of around 100 individual academies with hundreds of Fellows each. While individual networks are specialised in certain scientific areas, the SAPEA project combines these respective areas of expertise and ensures the inclusion of all scientific disciplines (social, human, natural, engineering and medical sciences). In view of the increasing complexity of today’s societal challenges and the growing need for independent interdisciplinary scientific evidence to inform policymaking, the project’s core objectives are to provide science-based policy advice and scientific inputs in different formats (e.g. evidence reviews, scientific statements, reports and studies) for evidence-based policymaking to the European Commission (EC) and the wider public within the Scientific Advice Mechanism of the EC; and to strengthen cooperation and foster synergies of the Academy Networks and their member academies, as well as making the existing structures more sustainable. The working groups made up of academy Fellows and other outstanding experts are the key component in providing interdisciplinary scientific policy advice. Through the project, the Academy Networks will offer their Fellows across Europe a platform to work jointly on projects of common interest. Topics for co-created publications and outputs may either be proposed by the academies or the EC may request scientific advice for a specific policy issue. Joint workshops aimed at empowering individual academies will be conducted to enhance cooperation between academies across scientific domains and with the five Academy Networks. A dedicated communications office will support the communication and dissemination of the project’s results which will also be published on the project website.";6000000;6000000;H2020-IBA-EUROPE-ENA-2016;/CSA;DEUTSCHE AKADEMIE DER TECHNIKWISSENSCHAFTEN;DE;"CONSEIL EUROPEEN DES APPLICATIONS DE LA SCIENCE ET DE L'INGENIERIE (EURO-CASE);FEDERATION OF EUROPEAN ACADEMIES OF MEDICINE;ACADEMIA EUROPAEA (THE ACADEMY OF EUROPE);All European Academies;DEUTSCHE AKADEMIE DER NATURFORSCHERLEOPOLDINA EV";"FR;BE;UK;DE";;1;0;0;2;0;0 201046;702529;MICROARCHAEODUNG;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Human-animal interactions in early sedentary and urban societies in the Near East and northern Africa: microarchaeology of livestock dung;2016-06-01;2018-05-31;;Livestock dung is commonly found in many human settlements, especially after the domestication of herds. Although receiving increasing attention in archeology, dung materials and secondary products are still routinely overlooked and this area of research is under-developed despite their worldwide importance as suppliers of manure, fuel source, temper and building material. This oversight is due in part to methodological problems in identifying dung during excavation and many bulk analyses, which destroy critical evidence on dung form, content, deposition and preservation in archaeological assemblages. This research will develop new interdisciplinary analytical strategies for microarchaeological study of dung combining geoarchaeology, bioarchaeology and biochemistry and experimental and ethnoarchaeological approaches. This integrated methodology will be applied to examine the context and content of livestock dung from mobile hunting-gathering to more sedentary farming Neolithic case-studies selected on a transect through the Near East, one of the key heartlands in which plants and animals that were later domesticated occur naturally, to the still little investigated northern Africa, a potentially critical area with implications for surrounding areas including the Mediterranean and the Sahara. It will also provide exciting new insight into the role of livestock and livestock dung in the development of more complex urban societies in Eastern Maghreb. These case-studies offer rich dung evidence for tracing human-animal interactions in different regions through time and key episodes of environmental and social change. The proposed project will establish a standard state-of-the-art interdisciplinary methodology for insight into archaeological dung as a valuable source of information on diverse cultural and economic aspects of past life-ways and the developments early farming and complex urban communities more widely.;183454,8;183454,8;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;THE UNIVERSITY OF READING;UK;;;;1;0;0;2;0;0 195666;658813;Old and New;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;How Old and New Media Influenced Each Other and Society in Iceland during the 16th and 17th Centuries;2015-06-01;2017-05-31;;"The influence of a the new medium of print on the old, existing medium of handwriting has never been examined before. The printing press came already around 1530 to Iceland and the earliest printed books were strongly influenced by handwritten manuscripts, which is well documented. A phenomenon which has not yet been analysed is that, as time went on, books in return influenced manuscripts. Manuscript production did indeed not stop after 1530, but grew to new quantitative and qualitative heights, including features of printed books such as title pages. I therefore propose to conduct a study on the relationship between books and manuscripts of the 16th and 17th centuries. The focus will be on title pages, as they are a truly innovative feature of printed books that we also find in post-Gutenberg manuscripts. The objectives of this project concern: a) The influence of a new medium on an existing medium b) The utilisation of features of the new medium to achieve specific aims and goals c) The impact of this utilisation on society Methods to conduct the study of title pages and their sociological impact include content analysis from literary studies, quantitative codicological analysis from book and manuscript studies, and iconographic/iconologic analysis from art history. This project has ground-breaking potential. It will provide insight into the ways features of new media were incorporated into existing media and how they were utilised. It will be the first systematic survey of its kind in Iceland and, concerning the influence of printed books on post-Gutenberg manuscripts, internationally. It will also be one of the first systematic interdisciplinary studies. It will be the forerunner of a larger project about Icelandic book and manuscript history and media changes with more researchers involved. The beneficiary has perfect conditions for interdisciplinary research and career development at the host institution and secondment and will complete the first step toward a full professorship.";166156,8;166156,8;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;OESTERREICHISCHE AKADEMIE DER WISSENSCHAFTEN;AT;;;;1;0;0;2;0;0 193417;636746;HUCO;SIGNED;H2020-EU.1.1.;ERC-StG-2014;H2020;Human Cooperation to Protect the Global Commons;2015-08-01;2020-07-31;;"The objectives of this research are to reveal the nature of large-scale human cooperation and to develop strategies for the protection of our global environment. Human activities are now the major driver of change in the biosphere, including the climate, the water cycle, and the distribution of species and biodiversity – with adverse effects that range from the local to the global scale. Since there is no world government that can enforce the protection of the global commons we have to rely on voluntary cooperation by sovereign actors. Previous findings from various disciplines have taught us important lessons about the nature of human cooperation. However, these literatures have almost exclusively focused on local or regional cooperation problems and their findings cannot be readily transferred to the international level. The research proposed here will fill this crucial gap. The methodological approach is genuinely interdisciplinary. In particular, the project will use and combine theoretical, experimental, evolutionary, and empirical methods. The interdisciplinary research team will start by analyzing case studies of international cooperation (or lack thereof). In an iterative process, the case-specific results will be explored in a rigorous context-free analysis using theoretical modeling, experiments, and simulations. With this, the project will: systematically analyze human cooperation from the local to the global scale and the differences between those scales; investigate which institutional arrangements enhance or prevent cooperative behavior at the global level; investigate whether individuals and groups are able to choose the right institutions and which factors determine their choice; synthesize the results to derive theoretical and practical insights about human cooperation and develop effective strategies for the management of the global commons; bring forward the integration of concepts and methods across disciplines for the study of human cooperation.";1500000;1500000;ERC-2014-STG;/ERC-STG;UNIVERSITAET KASSEL;DE;;;;1;0;0;2;0;0 205173;675341;PDZnet;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2015-ETN;H2020;Unraveling Principles of PDZ-mediated Cell Signaling;2016-09-01;2020-08-31;;PDZnet will create an innovative European PhD training network focusing on unraveling PDZ domain-mediated signaling networks. The emphasis will be on signaling nodes essential for the development of cancer and diseases of the nervous system, conditions that affect millions of Europeans and are major societal challenges. PDZ domains are protein and lipid recognizing modules that play a central role in trafficking and organizing diverse cell signaling assemblies, thereby allowing information to be transmitted from receptors, ion channels and transporters in the cell membrane. PDZ domain mediated interactions are emerging as conceptually novel and promising drug targets, with exciting opportunities for the development of novel therapies, especially within cancer and brain diseases. We will establish a European multidisciplinary platform integrating a plethora of complementary life science disciplines that range from chemical development of inhibitors to studies in live animals. The network encompasses 8 academic and 2 industrial beneficiaries as well as one industrial and one academic partner, which are all committed to promote frontline research, innovation and educational activities within the study of PDZ domain-mediated signal transduction pathways related to brain diseases and cancer. This interdisciplinary network will establish an outstanding training opportunity for Early Stage Researchers, who will be integrated in projects unraveling intracellular PDZ domain interactomes to provide pertinent information for discovering drug-related interactions. In a comprehensive and integrated training effort, involving a combination of scientific and transferable skills, the students will receive an interdisciplinary, intersectoral and innovative doctoral training from experienced industrial and academic leaders in well-reputed European Institutions.;3733514,66;3733514,66;H2020-MSCA-ITN-2015;/MSCA-ITN-ETN;KOBENHAVNS UNIVERSITET;DK;"INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE;EUROPEAN MOLECULAR BIOLOGY LABORATORY;UPPSALA UNIVERSITET;CENTRE EUROPEEN DE RECHERCHE EN BIOLOGIE ET MEDECINE;INSTITUT PASTEUR;JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN;SYSTASY BIOSCIENCE GMBH;NOVO NORDISK A/S;UNIVERSITA DEGLI STUDI DI ROMA LA SAPIENZA";"FR;DE;SE;DK;IT";;1;0;0;2;0;0 199715;666773;BlueHealth;SIGNED;H2020-EU.3.1.2.;PHC-04-2015;H2020;Linking Up Environment, Health and Climate for Inter-sector Health Promotion and Disease Prevention in a Rapidly Changing Environment;2016-01-01;2020-06-30;;"The BlueHealth Consortium brings together a multi-disciplinary team of experts reaching across all 28 European Union countries. The proposed 4.5 year BlueHealth Project takes an international, interdisciplinary and multi-sector approach to health promotion and disease prevention by investigating the relationship between the EU’s ‘blue infrastructure’ and the health and well-being of its citizens. Blue infrastructure refers to the network of natural and man-made aquatic environments providing a range of multi-sectorial services (e.g. transportation, fresh water provision). There has been no systematic attempt to detail the potential impacts of our blue infrastructure on health promotion and disease prevention, nor to develop guidelines on how health should be considered when developing blue infrastructure interventions, particularly across sectors. BlueHealth will address this gap. The majority of Europeans live in cities built on inland waterways, lakes, or the coasts. BlueHealth will focus on urban blue infrastructures. The EU’s blue infrastructure offers significant health and well-being related opportunities and benefits (eg urban cooling, recreation), but also challenges and stressors (eg flooding, microbial/chemical pollution). BlueHealth will investigate these trade-offs, with the aims of quantifying the impacts on population health and well-being of interventions and policy initiatives connected to blue infrastructure, and identifying success factors and obstacles of inter-sectorial collaborations. Assessments of health and environment benefits, risks and costs will improve our understanding of the role of urban blue infrastructures on across-sector health promotion and disease prevention. The Partners have collaborations across the Environment, Health, and Climate sectors, and extensive experience with inter-institutional, multi-sectorial, interdisciplinary research programmes employing innovation, stakeholder engagement, dissemination, and policy impact.";5998671,25;5998671,25;H2020-PHC-2015-two-stage;/RIA;THE UNIVERSITY OF EXETER;UK;"LUNDS UNIVERSITET;FUNDACIO CENTRE DE RECERCA EN EPIDEMIOLOGIA AMBIENTAL - CREAL;ARISTOTELIO PANEPISTIMIO THESSALONIKIS;ISTITUTO SUPERIORE DI SANITA;FUNDACION PRIVADA INSTITUTO DE SALUD GLOBAL BARCELONA;RIJKSINSTITUUT VOOR VOLKSGEZONDHEID EN MILIEU;EESTI MAAULIKOOL;FONDAZIONE CENTRO EURO-MEDITERRANEOSUI CAMBIAMENTI CLIMATICI;WORLD HEALTH ORGANIZATION";"SE;ES;EL;IT;NL;EE;CH";;1;0;0;2;0;0 221459;837854;ASSET;SIGNED;H2020-EU.3.3.;LC-SC3-CC-5-2018;H2020;A holistic and Scalable Solution for Research, Innovation and Education in Energy Transition;2019-05-01;2021-04-30;;ASSET´s goal is twofold: first, to create a sustainable and scalable ecosystem including all energy transition and education stakeholders: a) Companies from the energy sector, b) Universities and training actors, c) Authorities and policy makers and d) Society so as to enable a) continuous bottom up creation of research, innovation and educational (RIE) services and b) capacity pooling. By “service” we mean any research, innovation and educational relevant service that can be developed by the educational actors and delivered to the energy sector businesses and society at large. ASSET will also involve actors that can contribute to fuel interdisciplinary research combining SSH disciplines and capable of reaching out to the society to create the new generation of energy-sensitive citizens that are part of the energy transition mission. And second, to deliver the framework and means for continuous collaborative definition of the knowledge-competencies-skills required for the energy transition and for continuous resource pooling to efficiently educate/train large numbers of people in diverse and interdisciplinary topics and carry out research and innovation activities. The implementation of the ASSET approach will take place in 3 phases: 1) Ecosystem set-up with relevant actors to identify the knowledge, skill and competencies gaps in the addressed fields in order to design appropriate RIE services to close the gap. 2) RIE service development: Educational actors, based on the specifications of KSC gaps and on the results of the ASSET SSH research, will define the services (educational and research programme) that meet the specified needs. 3) Evaluation: ASSET delivers the developed RIE services to the targeted actors across EU universities, across companies from the energy sector and across EU societies. The aim is to collect feedback so as a) to refine ASSET offerings and b) define concrete ASSET sustainability plans;1999075;1999075;H2020-LC-SC3-2018-NZE-CC;/CSA;ATOS SPAIN SA;ES;"EDUCATIONAL OTE AE;PANEPISTIMIO DYTIKIS ATTIKIS;RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN;LOGICAL SOFT SRL;E' NOSTRA SOCIETA COOPERATIVA;UNIVERSITA DEGLI STUDI DI NAPOLI FEDERICO II;ECOPOWER;EUROPEAN ASSOCIATION FOR STORAGE OF ENERGY;UNIVERSITAT POLITECNICA DE VALENCIA;AALBORG UNIVERSITET";"EL;DE;IT;BE;ES;DK";;1;0;0;2;0;0 210607;754558;PREBIST;SIGNED;H2020-EU.1.3.4.;MSCA-COFUND-2016;H2020;COFUND BIST PREDOCTORAL PROGRAMME;2018-01-01;2022-12-31;;"The PREBIST proposal is presented by the Barcelona Institute of Science and Technology (BIST) as beneficiary. PREBIST is an ambitious programme of 28 four-year fellowships for multidisciplinary pre-doctoral research at BIST´s constituent research centres and associated partner institutions (hospitals, private companies, technology centres, and other academic institutions), who will provide secondments, training, networking activities and other actions to complement the research activities and professional development of the fellows. The PREBIST proposal is a major initiative by which BIST aims to leverage the combined capacities of the constituent centres in a manner which none of them could do on their own and help achieve the strategic objectives of BIST. Key objectives of PREBIST are to: • Boost the capacity for international talent attraction with increased visibility, strengthened recruitment processes, improved offerings of research areas with interdisciplinary and intersectorial aspects, and improved landing-pad processes to facilitate mobility; • Improve BIST centre capacities in the management of researcher career development, scientific and technical training, and new offerings in complimentary skills training and outreach activities; • Further drive interdisciplinary and intersectorial collaboration between BIST centres and other partner entities through joint research activities, secondments and technical trainings, improved access and utilisation of infrastructures, networking and development of personal contacts, joint seminars and workshops.";5859840;2929920;H2020-MSCA-COFUND-2016;/MSCA-COFUND-DP;THE BARCELONA INSTITUTE OF SCIENCE AND TECHNOLOGY;ES;;;;1;0;0;2;0;0 197247;642121;FULLCOMP;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2014-ETN;H2020;FULLY INTEGRATED ANALYSIS, DESIGN, MANUFACTURING AND HEALTH-MONITORING OF COMPOSITE STRUCTURES;2015-06-01;2019-05-31;;"Composite structures are massively exploited in many engineering fields. For instance, the state-of-the-art civil aircraft (B787 and A350) are mostly made of composite materials. The design of composites leads to challenging tasks since those competencies that stemmed from the adoption of metallic materials are often inadequate for composites. Insights on many different disciplines and tight academic/industrial cooperation are required to fully exploit composite structure capabilities. The skills and the employability of young researchers increase to a great extent through an interdisciplinary and intersectoral training. The existing training schemes are often based on specific themes and disciplines rather than on a broad interdisciplinary and academic-industrial integrated approach. The main aim and novelty of this project is the creation of a multidisciplinary, intersectoral and international research training network based on a strong academic basis and industrial partnerships for a new generation of top talented young researchers that will work in the European academic and industrial scenarios. The multidisciplinary features are guaranteed by the presence of 7 universities, 1 research centre and 1 industry. The intersectoral approach will be pursued by including secondments and specific industrial training requirements in each individual project. The consortium is composed by partners from 8 countries. OTC partners were included for secondment and training opportunities; they were chosen on the basis of their expertise and to enhance the internationality features of the training. Their presence is seen as an opportunity for the European partners and researchers to strengthen competencies. The full spectrum of the design of composite structures will be dealt with - manufacturing, health-monitoring, failure, modelling, multiscale approaches, testing, prognosis and prognostic - to develop integrated analysis tools to improve the design of composites.";3095280,36;3095280,36;H2020-MSCA-ITN-2014;/MSCA-ITN-ETN;POLITECNICO DI TORINO;IT;"ECOLE NATIONALE SUPERIEURE D'ARTS ET METIERS;ELAN-AUSY GMBH;LUXEMBOURG INSTITUTE OF SCIENCE AND TECHNOLOGY;UNIVERSITY OF BRISTOL;GOTTFRIED WILHELM LEIBNIZ UNIVERSITAET HANNOVER";"FR;DE;LU;UK";;1;0;0;2;0;0 207640;739562;DANUBIUS-PP;SIGNED;H2020-EU.1.4.1.1.;INFRADEV-02-2016;H2020;PREPARATORY PHASE FOR THE PAN-EUROPEAN RESEARCH INFRASTRUCTURE DANUBIUS–RI “THE INTERNATIONAL CENTRE FOR ADVANCED STUDIES ON RIVER-SEA SYSTEMS;2016-12-01;2019-11-30;;"DANUBIUS-PP is a three-year project to raise DANUBIUS-RI (International Centre for Advanced Studies on River-Sea Systems) to the legal, financial and technical maturity required for successful implementation and development. DANUBIUS-RI is a pan-European distributed research infrastructure (RI) building on existing expertise to support interdisciplinary research on river-sea (RS) systems, spanning the environmental, social and economic sciences. It will provide access to a range of RS systems, facilities and expertise, a ‘one-stop shop’ for knowledge exchange, access to harmonised data, and a platform for interdisciplinary research, education and training. DANUBIUS-PP will bring together key stakeholders at different levels, and strengthen the consortium through a process of wide engagement. Individual work packages will refine, inter alia, the scientific and innovation agenda, the legal framework, governance and management, and policies for access and data management. The financial requirements of the RI will be refined to assist funding agencies as they consider future spending priorities. Key deliverables of DANUBIUS-PP include development of the legal and financial agreements for the components of the RI (including Hub, Nodes and Supersites), their governance, and internal organisation which will be confirmed via a Memorandum of Understanding. This preparatory phase project will develop the structures and processes to ensure that the RI strengthens scientific performance by providing a sustainable basis for future operation, delivering key services to the different user communities.";4266405;3996405;H2020-INFRADEV-2016-2;/CSA;INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU GEOLOGIE SI GEOECOLOGIE MARINA-GEOECOMAR;RO;"INSTITUTUL DE CHIMIE ACADEMIA DE STIINTE A MOLDOVEI;UNIVERSITE DE LORRAINE;Bundesanstalt fuer Gewaesserkunde;USTAV VYZKUMU GLOBALNI ZMENY AV CR VVI;CORILA - CONSORZIO PER IL COORDINAMENTO DELLE RICERCHE INERENTI AL SISTEMA LAGUNARE DI VENEZIA;BULGARIAN ACADEMY OF SCIENCES;PLYMOUTH MARINE LABORATORY;EUROPPORTUNITIES OU;INTEGRATED CARBON OBSERVATION SYSTEM EUROPEAN RESEARCH INFRASTRUCTURECONSORTIUM;STICHTING IHE DELFT INSTITUTE FOR WATER EDUCATION;Unitatea Executiva pentru Finantarea Invatamantului Superior, a Cercetarii, Dezvoltarii si Inovarii;Odessa State Environmental University;HELLENIC CENTRE FOR MARINE RESEARCH;WasserCluster Lunz - Biologische Station GmbH;THE UNIVERSITY OF BIRMINGHAM;EUROPEAN MULTIDISCIPLINARY SEAFLOORAND WATER COLUMN OBSERVATORY - EUROPEAN RESEARCH INFRASTRUCTURE CONSORTIUM (EMSO ERIC);AUTORIDAD PORTUARIA DE SEVILLA;DIMOKREITIO PANEPISTIMIO THRAKIS;HELMHOLTZ-ZENTRUM GEESTHACHT ZENTRUM FUR MATERIAL- UND KUSTENFORSCHUNG GMBH;BUNDESANSTALT FUR WASSERBAU;THE UNIVERSITY OF STIRLING;UNITED KINGDOM RESEARCH AND INNOVATION;SZECHENYI ISTVAN UNIVERSITY;CONSIGLIO NAZIONALE DELLE RICERCHE;UNIVERSITAT POLITECNICA DE CATALUNYA;STICHTING DELTARES;Agentia de Administrare a Retelei Nationale de Informatica Pentru Educatie si Cercetare;UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK;INSTITUTUL NATIONAL DE CERCERTARE DEZVOLTARE PENTRU STIINTE BIOLOGICE RA;NATURAL ENVIRONMENT RESEARCH COUNCIL";"MD;FR;DE;CZ;IT;BG;UK;EE;FI;NL;RO;UA;EL;AT;ES;HU;IE";;1;0;0;2;0;0 206258;730211;T2S;SIGNED;H2020-EU.3.5.;SC5-28-2016;H2020;Transformations to Sustainability;2017-01-01;2021-12-31;;"The Transformations to Sustainability (T2S) ERA-NET Cofund programme will be implemented in the context of a Belmont Forum Collaborative Research Action in cooperation with the NORFACE (New Opportunities for Research Funding Agency Cooperation in Europe) network and the International Social Science Council (ISSC). A comprehensive and concerted research initiative is needed that can boost research on transformations to sustainability, that can catalyse new kinds of solutions to environmental and social challenges. This T2S programme therefore seeks to bring into being and nurture integrated teams of scientists from relevant academic disciplines including, as appropriate, social, natural, human, natural, engineering, agricultural and health/medical sciences disciplines and societal stakeholders to produce new knowledge and perspectives that can contribute to finding equitable and durable solutions to the challenges of sustainability in specific contexts, in support of the Sustainable Development Goals. This programme will contribute to re-structuring the broad field of sustainability research to place social science at the heart of interdisciplinary efforts and will contribute to a step change in scale and scope for research programming on this topic. This future-oriented call will be jointly undertaken by major funding agencies in Europa, the United States, Brazil, Taiwan and Japan. The T2S programme will coordinate the research efforts of the participating Member States and international partners by implementing a joint trans-national call with European Commission co-funding to fund innovative comparative, transnational and interdisciplinary research initiatives within this thematic field. The T2S partners will pursue the expansion of their present effective collaboration and actively strive at widening the consortium.";11771717,2;3585671,76;H2020-SC5-2016-OneStageB;/ERA-NET-Cofund;NEDERLANDSE ORGANISATIE VOOR WETENSCHAPPELIJK ONDERZOEK;NL;"ECONOMIC AND SOCIAL RESEARCH COUNCIL;CONSEIL INTERNATIONAL PROVISOIRE DES SCIENCES SOCIALES ASSOCIATION;VETENSKAPSRADET - SWEDISH RESEARCH COUNCIL;JAVNA AGENCIJA ZA RAZISKOVALNO DEJAVNOST REPUBLIKE SLOVENIJE;VALSTS IZGLITIBAS ATTISTIBAS AGENTURA;SUOMEN AKATEMIA;DEUTSCHES ZENTRUM FUER LUFT - UND RAUMFAHRT EV;UNITED KINGDOM RESEARCH AND INNOVATION;NORGES FORSKNINGSRAD;AN TUDARAS UM ARD OIDEACHAS;FONDS NATIONAL DE LA RECHERCHE;AGENCE NATIONALE DE LA RECHERCHE;FONDS VOOR WETENSCHAPPELIJK ONDERZOEK-VLAANDEREN;FONDS NATIONAL DE LA RECHERCHE SCIENTIFIQUE";"UK;FR;SE;SI;LV;FI;DE;NO;IE;LU;BE";;1;0;0;2;0;0 203099;707706;METODA;CLOSED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Methodological Explorations between Design and Social Sciences;2016-09-01;2018-02-28;;"The aim of this project is to explore how the repertoire of qualitative methods in the social sciences can be enriched by integrating methods and techniques from the fields of design and art to develop creative and novel modes of doing imaginative and critical research. This project attempts addresses recent calls within some social science disciplines such as sociology, human geography, media studies, anthropology, and Science and Technology Studies, for renewed approaches to methods. Recent works within different social science disciplines have stressed the need for methodologies capable of attending to the social and cultural world as mobile, digital, messy, interconnected, creative and sensory. There have been calls for social science methodologies that not only describe the worlds they observe but also are capable of intervening in and transforming them. This project begins from the premise that the creative, expressive, and participatory methods, techniques and practices within the fields of design and art constitute fertile ground for developing methodological innovation within the social sciences. The project will develop a database of examples of projects that have developed interdisciplinary methods between social science and design, conduct interviews with academic researchers and industry practitioners using innovative methods conduct workshops to explore how new methodological tools for collecting analyzing and communicating research data can be developed and applied. Ultimately, the project will develop new knowledge and innovation on interdisciplinary methods between design and the social sciences and develop new methodological tools and devices for collecting, analyzing, and communicating research data.";137591,1;137591,1;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;THE UNIVERSITY OF WARWICK;UK;;;;1;0;0;2;0;0 201571;708041;CIRCLE;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Investigation of the role of CYLD in Chronic Lymphocytic Leukaemia;2016-04-15;2018-04-14;;"This project will investigate the role of CYLD in Chronic Lymphocytic Leukaemia (CLL). CYLD is a deubiquinating enzyme acting as a tumour suppressor in numerous tumours. CLL is characterized by the accumulation of B-lymphocytes. It affects mostly the elder and has a high incidence rate in Europe. Recent data from CYLD knockout murine models indicate a link between CYLD and CLL, however the approach used for generation of these mice led to contrasting results. At the core of this interdisciplinary project is the generation of two transgenic murine with: i) targeted CYLD inactivation in B-lymphocytes, ii) targeted inactivation combined with a murine model of CLL. Targeted inactivation will be achieved using the Cre-Lox system, by crossing already available progenitor mice. The mice will be extensively characterized with an emphasis on B-lymphocytes development and pathophysiology. RNA-seq will be used to find differentially expressed genes in B-lymphocytes. Computational biology approaches will then be applied to identify the affected pathways, which will be evaluated against publicly available human CLL data, seeking wider consensus. CYLD targeted inactivation allows for the first time evaluation of CYLD's role in B-lymphocytes development and CLL ruling out the effect CYLD inactivation in other cells may have. This project will enable better understanding of the role of CYLD in B-lymphocytes biology and could unravel novel biomarkers and therapeutic targets. At the same time the applicant will train-through-research, master novel techniques and develop soft skills valuable for his future career. This project combines the applicant’s expertise in the generation and characterization of murine models with targeted CYLD inactivation with the host's long track record in B-lymphocytes and CLL.It falls well within the EU’s research agenda, which emphasizes interdisciplinary research leading to recognition of common disease mechanisms and identification of novel biomarkers.";180277,2;180277,2;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;UNIVERSITA VITA-SALUTE SAN RAFFAELE;IT;;;;1;0;0;2;0;0 201660;709298;INTERHYTHM;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Rhythms In Social Interaction;2016-06-01;2018-05-31;;Social interactions are ubiquitous and our globalized society challenges us with increasingly complex social environments. Yet, evolution has equipped humans with a unique capacity to navigate our social worlds, namely the capacity for rhythmic interpersonal coordination. Despite its relevance, social neuroscience studies have largely ignored this phenomenon, due to methodological constraints inherent in the nature of social interaction. In light of new technological advancements, however, the overarching aims of the proposed project are: (1) to implement an interdisciplinary psychological and neuroscientific approach and a novel experimental methodology that combines Virtual Reality (VR) and functional Near-Infrared Spectroscopy (fNIRS), in order to (2) understand how social interaction is both expressed in and shaped by rhythmic interpersonal coordination on both a behavioural and a neural level, and to (3) determine whether individuals with autism spectrum disorder (ASD) and typically developed individuals differ in their capacity to rhythmically coordinate their motor actions. Thus, the proposed interdisciplinary project combines social psychology research with technical virtual reality innovations and envisages behavioural (synchroneous tapping paradigm), neuroimaging (fNIRS) and clinical (ASD) implementations. It will result in a high-quality scientific programme with long-term potential, by laying the groundwork for the adoption of the concept of “Social Interaction Rhythms” in social neuroscience.;183454,8;183454,8;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;UNIVERSITY COLLEGE LONDON;UK;;;;1;0;0;2;0;0 196137;661646;CAMP-BIVALENCE;TERMINATED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Roma, Gypsies and Travellers' social in/exclusion in European urban camps;2016-09-01;2018-09-01;;"The project aims to analyse the role of Civil Society Organisations (CSOs) in Roma, Gypsies and Travellers’ (RGTs) in/exclusion in European urban camps. Triangulating individual semi-structured interviews, oral histories, archival research, and interpretative policy analysis, the interdisciplinary project combines Sociological, Socio-Anthropological and Socio-Historical approaches, contemplating two UK and two Italian superdiverse urban contexts as case studies. It contributes to three research streams: housing exclusion; RGT policy, and camps as socio-spatial configurations, and inaugurates a new interdisciplinary research field on Urban Camps. Dr Sigona, who will act as the Supervisor, is a leading scholar in migration and Roma research in Europe; his expertise is particularly complementary with Dr Picker research skills and knowledge coming from ten years of Sociological field-based research on Roma spatial segregation in five European countries. Due to the excellent quality of infrastructure, scholarly research and staff, the School of Social Policy and the Institute for Research into Superdiversity at the University of Birmingham are the most appropriate academic environment for Dr Picker to become, after the Fellowship, a leading social science scholar in the European Research Area.";195454,8;195454,8;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;THE UNIVERSITY OF BIRMINGHAM;UK;;;;1;0;0;2;0;0 201271;704920;ADAPTIVE INVERSIONS;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Chromosomes on shuffle: disentangling the relative contributions of natural selection, sexual selection, and drift on the evolution of a chromosomal inversion.;2016-05-01;2018-04-30;;Comprehending adaptation is key to understanding our changing world. Despite this, we still know little about the genetic basis of adaptation. The picture becomes even more complex when we move beyond base pairs to large structural variation. Inversions may contain hundreds or thousands of loci but segregate largely as one unit, as they prevent recombination. Nonetheless, these giant genomic units seemingly facilitate rapid adaptation and speciation in a wide variety of taxa. The key objective of this project is to determine how inversions contribute to adaptation and how they evolve by systematically examining and disentangling the forces that govern the evolution of an inversion in a model species, the seaweed fly Coelopa frigida. I will combine interdisciplinary techniques to address crucial and novel aspects of the relationship between inversions and adaptation. I will be based at the Linnaeus Centre for Marine Evolutionary Biology (CeMEB), an interdisciplinary centre of research excellence at the University of Gothenburg (UGOT) in Sweden. Via training-through-research including a secondment to the Instituto Gulbenkian de Ci?ncia in Portugal I will learn new techniques from multiple disciplines, including advanced scripting for analysis of next generation sequencing data, theoretical modelling, and reduced representation library preparation and analysis.;173857,2;173857,2;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;GOETEBORGS UNIVERSITET;SE;;;;1;0;0;2;0;0 220823;811312;ACO;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2018;H2020;AstroChemical Origins;2019-05-01;2023-04-30;;"The project ACO (AstroChemical Origins) has two main objectives: 1) to unveil the early history of the Solar System, using the chemical composition of today forming Solar-like planetary systems and comparing it with that of the Solar System primitive bodies; 2) to train a new generation of researchers able to tackle this highly interdisciplinary problem, providing them with a wide-range of transferable skills, including the ability to communicate Science to a large audience. This will be obtained by setting up: (a) a coordinated network of PhD research projects which will be carried out by 17 ESRs under the supervision of members of the ACO Beneficiaries; (b) a structured secondment network, to expose ESRs to alternative research environments; (c) a significant exposure of ESRs to the non-academic sector, via PhD co-supervision, secondment, short visits and training from non-academic ACO Beneficiaries and Partners; (d) specific courses at the host institutions as well as network schools with specialized interdisciplinary and transferable skills courses; (e) international conferences open to the scientific community; (f) several activities to make ACO network and its science known to the general public. In order to achieve the ACO objectives, the proposed network is constituted by fourteen Beneficiaries, whose four from the non-academic sector, plus seven Partner Organisations, whose six from the non-academic sector. Each Participating Organization will provide a complementary expertise indispensable to achieve of the ACO objectives: (i) instrumental, observational, theoretical, computational, modeling, and experimental to reach the scientific goal and, (ii) on informatics, scientific presentation and management, for completing the wide-transferable training.";4138452,54;4138452,54;H2020-MSCA-ITN-2018;/MSCA-ITN-ETN;UNIVERSITE GRENOBLE ALPES;FR;"INSTITUT DE RADIO ASTRONOMIE MILLIMETRIQUE SOCIETE CIVILE;MASTER-UP SRL;THE UNIVERSITY OF MANCHESTER;UNIVERSITA DEGLI STUDI DI TORINO;ISTITUTO NAZIONALE DI ASTROFISICA;POAM ELECTRONICS;UNIVERSITA DEGLI STUDI DI TRENTO;UNIVERSITE D'AIX MARSEILLE;UNIVERSITAT AUTONOMA DE BARCELONA;UNIVERSITY COLLEGE LONDON;UNIVERSITA DEGLI STUDI DI PERUGIA;UNIVERSITE PAUL SABATIER TOULOUSE III";"FR;IT;UK;ES";;1;0;0;2;0;0 221388;824047;LIFEBOTS Exchange;SIGNED;H2020-EU.1.3.3.;MSCA-RISE-2018;H2020;LIFEBOTS Exchange - creating a new reality of care and welfare through the inclusion of social robots.;2019-04-01;2023-03-31;;"The project aims enhancing cross-sector, international and interdisciplinary collaboration in the area of social robotics technology for care. Are robots ready for society, and is society ready for robots? How can social robots can be included in people’s lives? Robots are increasingly being used in the healthcare sector as a potential solution to the current and future challenges faced by the healthcare sector. Due to the global population ageing, by 2035 the world is projected to lack 12.9 million healthcare professionals (WHO: 2013). Social robots may benefit the quality life and wellbeing of patients, their families and healthcare professionals. Evidence and much of the needed knowledge are still lacking. Strong interdisciplinarity and cross-sectorial research and innovation activity is needed. A knowledge hub for social robotics will be created with a threefold aim: (1) To enhance the competencies of involved staff members, refining and focusing their skills; (2) To build a tri-sectoral network involving academia, industry and users of technology, and (3) to create an enduring network that will outlive the grant funding. The core of the project includes some of the strongest actors in international research, SMEs and user organisations, focusing on three activity lines: technological, sociological, care-and-welfare. To be able to understand the impact of introducing social robots in care, the three areas that will be affected by this technical evolution will be researched: (1) care provided as medical practice; this is the care given to patients in hospitals, clinics, rehabilitation centres and other medical facilities. (2) residential care - this area refers to all care institutions accepting patient/clients as residents: elderly homes, nursing homes, special needs schools for children or adults, etc. (3) family care, investigating how social robots can be implemented in the home, and as a part of domestic life.";768200;740600;H2020-MSCA-RISE-2018;/MSCA-RISE;NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU;NO;"TECHNICKA UNIVERZITA V KOSICIACH;INSTITUTO PEDRO NUNES ASSOCIACAO PARA A INOVACAO E DESENVOLVIMENTO EM CIENCIA E TECNOLOGIA;COMPEXIN SA;ETHNIKO KENTRO EREVNAS KAI TECHNOLOGIKIS ANAPTYXIS;EUROPEAN HEALTH TELEMATICS ASSOCIATION;INSTITUTO DE SISTEMAS E ROBOTICA-ASSOCIACAO;UNIVERSITE DE GENEVE;IDMIND - ENGENHARIA DE SISTEMAS LDA;CARITAS DIOCESANA DE COIMBRA;CO-ROBOTICS SRL;UNIVERSITETSSYKEHUSET NORD-NORGE HF";"SK;PT;RO;EL;BE;CH;IT;NO";;1;0;0;2;0;0 215455;796557;INMARE;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Injectable hydrogels for magnetically-activated, remote-controlled drug delivery;2019-01-22;2022-01-21;;The key goals of the INMARE project are: a) the training of a talented and experienced researcher, Dr Eneko Axpe, in the science, technology and industrial application of magnetic nanomaterials and drug delivery systems. The host and partners have critical knowledge and expertise in these fast growing fields. And b) the design, fabrication and (further) development of a minimally invasive, externally triggered, on demand drug delivery system. This interdisciplinary training program includes fabrication and full characterization of injectable nanocomposites, development of physical models of the drug diffusion in hydrogels, and application of AC magnetic fields for drug delivery. Such a program will support the talented researcher, who has already gained expertise in the area of nanomaterials for biomedical applications during his postgraduate career, in his endeavour to increase his exposure to both academic and industrial collaborations. To further his career in biomaterials, Dr Eneko Axpe envisions pursuing an extensive study of smart materials and their in vivo applications, fields which the partner at Stanford University and the host group at UPV/EHU have a world-recognized expertise in. Additionally, through a secondment at AstraZeneca, his industrial co-partner, he will receive further training in pharmacokinetics and the commercial applications of health products. The applications of this project are vast, ranging from medical treatments of chronic diseases such as cancer, to a basic understanding of the physics behind drug diffusion, which attest to its interdisciplinarity and high impact. Moreover, it will provide Dr Eneko Axpe with the opportunity to increase his supervision and teaching experience, gain project and intellectual property management expertise, research funding and proposal writing skills. Multidisciplinary activities will assist the experienced researcher in acquiring necessary competences and reaching professional maturity.;239191,2;239191,2;H2020-MSCA-IF-2017;/MSCA-IF-GF;UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA;ES;;;;1;0;0;2;0;0 198832;690850;RUBICON;SIGNED;H2020-EU.1.3.3.;MSCA-RISE-2015;H2020;Training network for Research on molecUlar and Biomechanical Interactions in CONnective tissue disorders;2016-01-01;2019-12-31;;"RUBICON will establish a global network for staff exchange of scientists and for research training focussed on connective tissue disorders. It will bring together leading scientific groups from 5 European and 5 non-European countries who will study the molecular and biomechanical factors involved in the pathophysiology of connective tissues, including tendons, cartilage and bone. The ambitious objectives of RUBICON are to increase our knowledge of the mechanisms underlying diverse connective tissue disorders, identify commonalities and targetable pathways, and reinforce multidisciplinary awareness in this fundamental research field. Researchers involved in secondments between RUBICON participants will investigate genetic determinants, circadian clock, extracellular matrix components, soluble biochemical factors and intracellular signalling pathways, ER stress and oxidative components involved in connective tissue homeostasis and pathogenesis. Extensive training during secondments will include new technologies and innovation, study design, interdisciplinary laboratory research, data analysis, research management, ethics in animal and human studies, and development of scientific and communication skills. All participating laboratories will ensure attractive working conditions in excellent and internationally recognised institutions, equipped with state-of-the-art instruments and excellent core facilities. Webinars, courses and meetings will provide additional opportunities for training and networking, also be open to external participants. RUBICON is a unique interdisciplinary network including cell biologists, molecular biologists, animal biologists, morphologists, geneticists, biochemists and clinicians who will cross-fertilise their respective research fields. The long-term goal of RUBICON is to consolidate a class of young scientists to secure future developments in the connective tissue arena and create a solid basis for further collaboration in this field.";877500;607500;H2020-MSCA-RISE-2015;/MSCA-RISE;UNIVERSITA DEGLI STUDI DELL'AQUILA;IT;"REGION HOVEDSTADEN;THE UNIVERSITY OF MANCHESTER;UNIVERSITY OF NEWCASTLE UPON TYNE;ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM";"DK;UK;NL";;1;0;0;2;0;0 193612;638992;OPT4SMART;SIGNED;H2020-EU.1.1.;ERC-StG-2014;H2020;Distributed Optimization Methods for Smart Cyber-Physical Networks;2015-10-01;2020-09-30;;The combination of embedded electronics and communication capability in almost any mobile or portable device has turned this century into the age of cyber-physical networks. Smart communicating devices with their sensing, computing and control capabilities promise to make our cities, transportation systems, factories and living environments more intelligent, energy-efficient, safe and secure. This extremely complex system has raised a number of new challenges involving ICT disciplines. In particular, a novel peer-to-peer distributed computational model is appearing as a new opportunity in which a service is built-up cooperatively by peers, rather than by a unique provider that knows and owns all data. The interdisciplinary “Optimization Community” is facing this revolution sharing a common need: to find new theories, methodologies and tools to optimize over this complex network system. With this in mind, OPT4SMART has a twofold objective. First, to provide a comprehensive theoretical framework to solve distributed optimization problems over peer-to-peer networks. Second, to develop effective numerical tools, based on this framework, to solve estimation, learning, decision and control problems in cyber-physical networks. To achieve this twofold objective, we will take a systems-theory perspective. Specific problems from these four areas will be abstracted to a common mathematical set-up, and addressed by means of interdisciplinary methodologies arising from a synergic combination of optimization, controls, and graph theories. In particular, OPT4SMART will face the challenge of solving optimization problems under severe communication limitations, very-large-scale problem and data size, and real-time computational constraints. The expected result will be a combination of strong theoretical methods and effective numerical toolboxes available to people in Engineering, Computer Science, Mathematics and other areas, who are facing optimization in cyber-physical networks.;1488750;1488750;ERC-2014-STG;/ERC-STG;UNIVERSITA DEL SALENTO;IT;;;;1;0;0;2;0;0 204440;679681;Tamed Cancer;SIGNED;H2020-EU.1.1.;ERC-StG-2015;H2020;Personalized Cancer Therapy by Model-based Optimal Robust Control Algorithm;2016-07-01;2021-06-30;;"Imagine if tumor growth would be reduced and then kept in a minimal and safe volume in an automated manner and in a personalized way, i.e. cancer drug would be injected using a continuous therapy improving the patient’s quality of life. By control engineering approaches it is possible to create model-based strategies for health problems. Artificial pancreas is an adequate example for this, where by continuous glucose measurement device and insulin pump it is possible to improve diabetes treatment. Gaining expertise from this problem, the current proposal focuses on taming the cancer by developing an engineering-based medical therapy. The interdisciplinary approach focuses on modern robust control algorithm development in order to stop the angiogenesis process (i.e. vascular system development) of the tumor; hence, to stop tumor growth, maintaining it in a minimal, “tamed” form. This breakthrough concept could revitalize cancer treatment. It is the right time to do it as some investigations regarding tumor growth modeling have been already done; now, it should be refined by model identification tools and validated on animal trials. The benefit of robust control was already demonstrated in artificial pancreas; hence, it could be adapted to cancer research. The result could end with a personalized healthcare approach for drug-delivery in cancer, improving quality of life, optimizing drug infusion and minimizing treatment costs. This interdisciplinary approach combines control engineering with mathematics, computer science and medical sciences. As a result, the model-based robust control approach envisage refining the currently existing tumor growth modeling aspects, design an optimal control algorithm and extend it by robust control theory to guarantee its general applicability. Based on our research background, validation will be done first in a manually controlled way, but then in an automatic mode to propose it for further human investigations.";1015900;1015900;ERC-2015-STG;/ERC-STG;OBUDAI EGYETEM;HU;SEMMELWEIS EGYETEM;HU;;1;0;0;2;0;0 194355;645668;SALEACOM;CLOSED;H2020-EU.1.3.3.;MSCA-RISE-2014;H2020;Overcoming Inequalities in Schools and Learning Communities: Innovative Education for a New Century;2015-01-01;2017-12-31;;"Overcoming Inequalities in Schools and Learning Communities: Innovative Education for a New Century (SALEACOM here after) proposes the collaboration between 7 research groups (Australia, Brazil, New Zealand, Hungary, South Africa, Spain, USA) and 1 non academic institution (Drom Kotar Mestipen) with a global scope to address educational and social exclusion in schools and learning communities. SALEACOM seeks to create an International Research Network that has the following aims: (i) to increase worldwide cooperation in the study of successful actions with children and youth systematically underserved; (ii) to provide high-quality training programs for teachers and educational researchers aiming at overcoming inequalities; (iii) to develop interdisciplinary solutions for and with learners most heavily affected by inequalities, including access and quality of higher education; (iv) to design strengths-based methodologies for international comparative research to further the impact of research on the lives of students who have been historically excluded (v) to create a global program of successful educational actions to be implemented across educational systems. To promote coherent and effective cooperation among the research team, it accounts for the inclusion of researchers across disciplines, stages in their careers and cultures, committed to conducting strengths-based international research to further impact the lives of students who have been traditionally unsuccessful in educational contexts. To maximise the research outcomes of this proposal, researcher exchanges are based on partners’ complementarities in skills, methodological expertise and knowledge of several excluded populations that face similar challenges globally (i.e. Roma, Indigenous populations, African American, among others.). In parallel to developing interdisciplinary successful educational actions in schools and learning communities, we will explore paradigms, principles and practices.";499500;391500;H2020-MSCA-RISE-2014;/MSCA-RISE;UNIVERSITAT ROVIRA I VIRGILI;ES;"KOZEP-EUROPAI EGYETEM;UNIVERSITAT DE BARCELONA;UNIVERSITAT AUTONOMA DE BARCELONA;ASOCIACION GITANA DE MUJERES DROM KOTAR MESTIPEN DE BARCELONA";"HU;ES";;1;0;0;2;0;0 211812;748961;URBAN_CHINA;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Urbanization in China's South-western Borderlands. The case of Jinghong, Xiguangbanna;2018-02-01;2020-05-31;;"This interdisciplinary research project aims to study urbanization in China’s non-metropolitan and non-industrial ethnic-diverse border regions under post-socialism. Literature on urbanization in China focuses mainly on traditional large metropolitan or industrial cities in the center with Han majority population, and examines either the structural or the subjective features of urban development. The complex dynamics of urbanization and power relations in the new cities in the periphery remain understudied. The project fills this knowledge gap, by exploring how urbanization intersects with tourism growth and in-migration and affects ethnic relations in Jinghong, a fast-growing city in China’s south-western borderlands. In Jinghong, the Han, China’s ethnic majority, have become the city’s drivers of urban and economic development, competing over land, resources and political power with long-term Dai/Tai minority ethnic residents. Unconventionally drawing on methods of Anthropology, Urban Planning, Architecture, Urban Geography, and Sociology, this pioneering project aims at producing a theoretically and empirically innovative analysis that combines structural, socio-economic, and political examination with an investigation of subjective and experiential aspects of urbanization, highlighting conflicts, mindsets, and prejudices in the day-to-day urban interactions between Han majority and ethnic minority citizens and the state. I expect that the development of this project will profoundly impact my career. Thanks to training provided by the Department of Architecture, Design and Urban Planning, at the University of Sassari, Italy’s utmost interdisciplinary institution of Architecture and Urban Planning, I will acquire new skills and build fruitful relations with European institutions and scholars. The training, network and publications of the project’s outcome will allow me to increase my possibilities of obtaining an ERC Grant.";168277,2;168277,2;H2020-MSCA-IF-2016;/MSCA-IF-EF-CAR;UNIVERSITA DEGLI STUDI DI SASSARI;IT;;;;1;0;0;2;0;0 210945;734271;PADDLE;SIGNED;H2020-EU.1.3.3.;MSCA-RISE-2016;H2020;Planning in A liquiD worlD with tropicaL StakEs: solutions from an EU-Africa-Brazil perspective;2017-07-01;2021-06-30;;"Marine environments are subject to growing pressures as traffic, increasing demand and changing land-use of coastal areas, seabed exploitation, dredging or mining, fishing, tourism, development of renewable energies, etc. Sustainably managed oceans and seas can contribute to economic growth and employment, and will allow the international community to meet its global targets, including the reduction of poverty and hunger as detailed in the global 2030 Sustainable Development Agenda. Thus, marine environments are considered opportunities for future growth not only in Europe, but also in bordering marine areas like the tropical Atlantic. As a consequence, new frameworks will be increasingly needed to regulate and optimize the range of feasible uses of marine areas and resources. Marine Spatial Planning (MSP) aims at reconciling human uses and conservation, and offers an attractive setting to combine different uses of marine resources within a single area. There is an urgent and critical need for research on the application of MSP in tropical areas. The research should critically address the fact that the policy framework originally designed for the European Union (EU) may not fit the specificities of Southern countries. PADDLE will bring together internationally renowned researchers and actors, from countries bordering the tropical Atlantic and from the EU, to create a network and a colloborative platform, which will build theory and methods for pertinent MSP in tropical areas. This interdisciplinary team will be a pillar of knowledge-based MSP by providing critical analyses of the tools and methods used, and by designing innovative approaches to efficient MSP. The PADDLE proposal will create the first North-South interdisciplinary consortium on MSP in the tropics, highlighting opportunities and limits of tropical MSP and producing toolboxes for a broad range of stakeholders.";1723500;1557000;H2020-MSCA-RISE-2016;/MSCA-RISE;INSTITUT DE RECHERCHE POUR LE DEVELOPPEMENT;FR;"FCIENCIAS.ID - ASSOCIACAO PARA A INVESTIGACAO E DESENVOLVIMENTO DE CIENCIAS;LEIBNIZ-ZENTRUM FUER MARINE TROPENFORSCHUNG (ZMT) GMBH;TERRA MARIS;UNIVERSITE DE BRETAGNE OCCIDENTALE;FUNDACAO GASPAR FRUTUOSO;WAGENINGEN UNIVERSITY;UNIVERSITE DE NANTES;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;CREOCEAN;UNIVERSIDAD DE SEVILLA";"PT;DE;FR;NL;ES";;1;0;0;2;0;0 215269;794549;Readers as Observers;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;The construction of readers as (co-)observers in multimodal novels. Radical reader engagement in the visual age;2018-09-01;2020-08-31;;"'The research action at the University of Oslo (UiO) takes its starting point from the striking appeal to the reader's visual perception in contemporary multimodal novels. Drawing on state-of-the-art research in interdisciplinary narratology, cognitive linguistics, and visual semiotics, the project analyses the strategies that enable multimodal novels to assign an observer role to the reader and present a narrative agent or the book itself as a 'co-observer' on eye-level. While research on contemporary English-language multimodal novels has laid important analytical groundwork, a more diachronic as well as comparative perspective remains a desideratum. The first objective of the project is thus to develop a comparative analytical model based on several case studies of German- and English-language multimodal novels and contrastive corpora of historical multimodal print media such as illustrated magazines. The notion of the reader-observer constitutes the model's nucleus since it allows to systematically address the textual strategies that 'materialise' the narration and appeal to the reader's (mental) eye. Building on this model, the second objective is to contribute on a larger scale to the seminal field of cognitive narratology and further its consideration of media and genre-historical contexts. To achieve these goals, the project draws on the innovative and interdisciplinary research environment at UiO's Faculty of Humanities and brings together experts from narratology, cognitive science, media studies and book history. The project's activities will includes a research workshop on 'Reader Response, Joint Attention, and Multimodality', an international conference on 'Readers as (Co-)Observers in Multimodal Print Media' and several public Round Table events at Oslo's House of Literature.'";196400,4;196400,4;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;UNIVERSITETET I OSLO;NO;;;;1;0;0;2;0;0 215764;799865;MessCa;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;The Messina Case: Mafia-type Organised Crime in the Province of Messina;2018-10-01;2021-03-01;;The 2013 Europol Threat Assessment concerning Italian organised crime outlines how the ongoing threat that mafias pose to the EU is ‘unparalleled by any other European Organised Crime Group’. Significant successes in judicial investigations have undoubtedly contributed to a better understanding of Italian mafias over time. However, the emergence and expansion of mafia groups in non-traditional areas of settlement leave aspects of the phenomenon still unexplored. This is the case of the Sicilian mafia in the province of Messina which, despite being the object of parliamentary inquiries, court cases, and increasing media attention, has largely been neglected by scholarly literature. The proposed research aims to fill this gap. Adopting an interdisciplinary approach, this project aims to trace the history and evolution of mafia groups in the province of Messina –what the judiciary refers to as ‘The Messina Case’– examining their structure, ethos and modus operandi. It will be conducted using a qualitative methodological framework within the interpretive tradition and will involve the analysis of legal documents and judicial papers, in-depth interviews with judicial and police authorities, and state witnesses. Such an interdisciplinary approach allows us to delineate the evolution and structure of mafia groups, their external and internal relations and flux of power, as well as the role that shared cultural values and social conventions play in the dynamics of identity formation. By identifying the components that the mafia in the province of Messina shares with traditional mafia groups in Sicily and Calabria whilst simultaneously exposing a unique reality, this project will advance current research into mafia expansion in non-traditional areas. Through a number of research outputs and engagement events, it will also create impact outside academia by furthering public and policy makers’ awareness on the socio-economic liability that mafia infiltration of territory entails.;168277,2;168277,2;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;UNIVERSITA DEGLI STUDI DI MESSINA;IT;;;;1;0;0;2;0;0 220741;823866;RISE_SMA;SIGNED;H2020-EU.1.3.3.;MSCA-RISE-2018;H2020;RISE Social Media Analytics;2019-01-01;2022-12-31;;"The purpose of RISE_SMA is to create an interdisciplinary, international network of excellent scholars and practitioners in the field of social media analytics (SMA). Given the ubiquity of social media, and the immense amount of new social media data continuously created, there is a growing need to derive meaningful insights from this “big” social data by combining different methods. Application areas range from crisis communication and political communication to marketing research and customer acquisition for businesses. The need for more interdisciplinary and international cooperation is especially evident in the two focus areas of RISE_SMA: crisis communication and the societal impact of social media. First, understanding the communication activities unfolding amongst ordinary citizens, and communicating crucial information to them in a timely and coordinated manner during a crisis is a prerequisite for the effective mitigation of its consequences. Practitioners in the field would benefit from more intensive collaboration with researchers, and researchers would benefit from better understanding the needs of decision-makers. At the same time, the wider impact of social media on society is still unclear. Recent advancements in technology have led to the emergence of new communication patterns; their impact and meaning have yet to be understood. On the one hand social media have been highlighted for enabling new forms of citizen engagement that strengthens civic participation at local and national levels, but on the other hand social media have been criticised for enabling the emergence of disconnected echo chambers in which political propaganda can circulate unchallenged. Hence, there is an urgent need for comprehensive concepts as well as methods which exist independent of particular current platforms and applications. Based on research in these fields, practical recommendations need to be derived and technical solutions need to be developed.";1168400;1168400;H2020-MSCA-RISE-2018;/MSCA-RISE;UNIVERSITAET DUISBURG-ESSEN;DE;"UNIVERSITEIT LEIDEN;UNIVERSITETET I AGDER;KRISTIANSAND KOMMUNE;VIRTIMO AG";"NL;NO;DE";;1;0;0;2;0;0 193937;642663;eCHO Systems;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2014-ETN;H2020;Enhancing CHO by Mammalian Systems Biotechnology (eCHO systems);2015-01-01;2018-12-31;;"Chinese hamster (CHO) ovary cells are the production host for a \50 billion €/yr biopharmaceuticals market. Current CHO production platforms dates to 1980 and are based primarily on media and process optimisation with little consideration to the optimization of the cellular machinery. Fortunately, with the recent sequencing of the CHO genome, an opportunity has opened to significantly advance the CHO platform. The benefit will be advanced production flexibility and a lower production cost. This ITN graduate training programme - eCHO Systems - will blend conventional molecular, cellular, and synthetic biology with genome scale systems biology training in ‘omics data acquisition, biological network modeling, and genome engineering in three interdisciplinary topics: 1) Acquisition of large scale ‘omics data sets and their incorporation into genome-scale mathematical models 2) Development of genome engineering tools, enabling synthetic biology 3) Application of systems and synthetic biology and genome engineering to improve performance of CHO producers The training projects are supported by 15 industrial participants, which will participate in the research and test the results. ESR training will include intense courses focused on computational systems biology, cell biology, business and entrepreneurship. The three universities bring unique complementary skills in systems and synthetic biology, ‘omics technologies, cytometry, and molecular cell biology which will provide depth and breadth to this training. The eCHO Systems will produce four major outputs: General knowledge to improve the productivity, quality, and efficiency of CHO platform cell lines, new systems models for CHO cells, new CHO cell line chassises generated through synthetic biology approaches, high quality education at the graduate level, and a cadre of interdisciplinary graduates poised to transform biopharmaceutical biotechnology.";4044794,43;4044793,68;H2020-MSCA-ITN-2014;/MSCA-ITN-ETN;DANMARKS TEKNISKE UNIVERSITET;DK;"DUBLIN CITY UNIVERSITY;ACIB GmbH;RENTSCHLER BIOTECHNOLOGIE GMBH;UCB PHARMA SA;UNIVERSITY OF KENT";"IE;AT;DE;BE;UK";;1;0;0;2;0;0 212009;781638;ESOF2018;SIGNED;H2020-EU.5.;IBA-SWFS-ESOF-2017;H2020;EuroScience Open Forum ESOF2018;2017-06-01;2018-11-30;;"ESOF (EuroScience Open Forum) is the largest interdisciplinary science meeting in Europe. It is dedicated to scientific research and innovation and offers a unique framework for interaction and debate for scientists, innovators, policy makers, business people and the general public. Created in 2004 by EuroScience, the non-profit grassroots association of researchers in Europe, this biennial, interdisciplinary, pan-European forum brings together over 4 000 researchers, educators, business actors, policy makers and journalists from all over the world to discuss breakthroughs in science. After Stockholm, Munich, Barcelona, Torino, Dublin, Copenhagen, Manchester, the 8th edition of ESOF will take place in Toulouse, France, from 9 till 14 July 2018. The motto of ESOF 2018 is “Sharing science: towards new horizons” and enrols itself in the “Open innovation, open science, open to the world” vision for Europe. ESOF’s Scientific Programme will deal with major societal challenges, such as sustainable cities, sustainable living, global change, science policy and transformation of research practice, health in our societies, understanding divided societies, and so on. The call for sessions strongly encourages the participation of society through innovative format and the alignment with one cross-cutting issue, such as gender issues or ethics. It is complemented by five other programmes: - the Science and Policy Programme, which addresses policies on science for Europe; - the Career programme, which is geared specifically towards young European researchers; - the Science to Business Programme, which addresses the involvement of the private sector in science and innovation; - the Media and Communication Programme, which targets media involvement in all forms with a specific agenda dedicated to science communication; - the Science in the City Programme which provides a scientific cultural programme to engage with the general public.";1234062,5;999999;H2020-IBA-SWFS-ESOF-2017;/CSA;COMMUNAUTE D'UNIVERSITE ET D'ETABLISSEMENTS UNIVERSITE FEDERALE DE TOULOUSE MIDI-PYRENEES;FR;;;;1;0;0;2;0;0 202589;681835;FLUDYCO;SIGNED;H2020-EU.1.1.;ERC-CoG-2015;H2020;Fluid dynamics of planetary cores: formation, heterogeneous convection and rotational dynamics;2016-07-01;2021-06-30;;Understanding the flows in planetary cores from their formation to their current dynamics is a tremendous interdisciplinary challenge. Beyond the challenge in fundamental fluid dynamics to understand these extraordinary flows involving turbulence, rotation and buoyancy at typical scales well beyond our day-to-day experience, a global knowledge of the involved processes is fundamental to a better understanding of the initial state of planets, of their thermal and orbital evolution, and of magnetic field generation, all key ingredients for habitability. The purpose of the present project is to go beyond the state-of-the-art in tackling three barriers at the current frontier of knowledge. It combines groundbreaking laboratory experiments, complementary pioneering numerical simulations, and fruitful collaborations with leaders in various fields of planetary sciences. Improving on the latest advances in the field, I will address the fluid dynamics of iron fragmentation during the later stages of planetary accretion, in order to produce innovative, dynamically reliable models of planet formation. Considering the latest published data for Earth, I will investigate the flows driven in a stratified layer at the top of a liquid core and their influence on the global convective dynamics and related dynamo. Finally, building upon the recent emergence of alternative models for core dynamics, I will quantitatively examine the non-linear saturation and turbulent state of the flows driven by libration, as well as the shape and intensity of the corresponding dynamo. In the context of an international competition, the originality of my work comes from its multi-method and interdisciplinary character, building upon my successful past researches. Beyond scientific advances, this high-risk/high-gain project will benefit to a larger community through the dissemination of experimental and numerical improvements, and allow promoting science through an original outreach program.;1992602;1992602;ERC-2015-CoG;/ERC-COG;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FR;;;;1;0;0;2;0;0 194579;649435;TransSOL;CLOSED;H2020-EU.3.6.;EURO-3-2014;H2020;European paths to transnational solidarity at times of crisis: Conditions, forms, role-models and policy responses;2015-06-01;2018-05-31;;"TransSOL is committed to the systematic, interdisciplinary and praxis-oriented analysis of European solidarity in times of crisis. It has three overarching objectives: (a) it will map and analyse solidarity in Europe by means of a cross-national database that comprises three surveys addressing the general population, organized civil society, and claims-making in the media; (b) it will gather systematic data on the contextual factors and engage into political and legal analyses to ascertain the influence of the socio-economic, political, and legal context on solidarity, in particular the impact of the crisis, the EU’s political responses and target-groups specific public policies; and (c) it will identify and develop best practices of transnational solidarity, draft evidence-based policy recommendations, and engage proactive dissemination and communication activities. The project comprises teams from Denmark, France, Germany, Greece, Italy, Poland, Switzerland and the UK, including scientists from various disciplines and civil society practitioners, thus promising to deliver interdisciplinary and comparative analyses, knowledge-transfer and evidence-based, practicable recommendations. The project will enable us to address the three topics of the call. First, TransSOL will provide the first rigorous and comprehensive analysis of transnational solidarity in Europe, its main forms, conditioning factors (e.g., individual features as gender and social class, spatial inequalities, and contextual factors), and underlying conflicts about contending norms, identities, and interests. Secondly, the project will address the impact of Europe’s cultural diversity and multiple identities on European solidarity by analysing public claims-making and debates within the media. And finally, we engage into a critical reflection about adequate policy responses, in particular about the potentials of social investments balancing civic virtues of solidarity with public responsibilities.";2847680;2483805;H2020-EURO-SOCIETY-2014;/RIA;UNIVERSITAET SIEGEN;DE;"UNIWERSYTET WARSZAWSKI;THE UNIVERSITY OF SHEFFIELD;UNIVERSITE DE GENEVE;UNIVERSITA DEGLI STUDI DI FIRENZE;FONDATION NATIONALE DES SCIENCES POLITIQUES;KOBENHAVNS UNIVERSITET;PANEPISTIMIO KRITIS;THE GLASGOW CALEDONIAN UNIVERSITY;EUROPEAN ALTERNATIVES LIMITED LBG;EUROPEAN ALTERNATIVES BERLIN E V";"PL;UK;CH;IT;FR;DK;EL;DE";;1;0;0;2;0;0 200430;701479;MONTEX;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;MONKS, NUNS AND TEXTILES: Production, Circulation, and Distribution of Textiles in the Monastic Environment in Egypt (4th-8th Centuries AD);2017-01-01;2020-05-17;;"The MONTEX project will consider Egyptian society in the Late Roman, Byzantine and Early Arab periods through its economy and material culture. It focuses on the production, circulation, and distribution of textiles. Textile production was one of the most important branches of the Egyptian economy at the time. This research will be conducted using the example of the monastic environment. As monks and nuns came from all social groups, their professional occupations and everyday life strongly correspond in many aspects with the lifestyle of lay people. The sources related to monastic environment are numerous and provide us with some information unavailable elsewhere regarding lay craftsmen and customers. This comparative research will be conducted in interdisciplinary studies combining all kinds of sources: archaeological evidence, iconographic representations, and literary, normative, and documentary texts written in a bilingual Greek and Coptic environment. The MONTEX project provides studies on the provision of raw materials, and the organisation of textile production and craft training, also considering the gender aspect of these topics. The studies of the circulation and distribution of textiles will focus on the innovative topic of textiles not destined for clothing and used in various contexts. It also offers new lexicographical approach to the Greek vocabulary concerning textiles and their production. The main goal of this research is a synthetic study of textiles in Late Roman and Byzantine Egypt, a topic which has never received interdisciplinary and comparative analysis. The Project will be hosted by the University of Copenhagen’s Centre for Textile Research (Denmark), a highly specialized centre for textile studies. The secondment institution will be the Université Paris Ouest – Nanterre La Défense (France), with its Department of Art History and Archaeology famous for teaching and research into Mediterranean material culture.";212194,8;212194,8;H2020-MSCA-IF-2015;/MSCA-IF-EF-RI;KOBENHAVNS UNIVERSITET;DK;;;;1;0;0;2;0;0 198326;676338;Tendon Therapy Train;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2015-ETN;H2020;Engineering in vitro microenvironments for translation of cell-based therapies for tendon repair;2016-02-01;2020-01-31;;Tendon Therapy Train is a research, training and innovation programme for human and equine tendon repair and regeneration that will exploit recent advancements in tissue engineering by self-assembly (TESA) technologies which have led to the clinical translation and commercialisation of advanced therapy medicinal products (ATMPs). Although TESA therapies have the potential to revolutionise healthcare for numerous clinical targets, a lack of researchers with the necessary interdisciplinary skillset to advance the field is limiting clinical translation. Tendon therapy train, a network of 8 beneficiaries and 8 partners (7 universities, 7 companies and 2 hospitals) from six countries across Europe, will train a cohort of 15 researchers to doctoral level in the interdisciplinary area of ATMPs. The innovative credentials of the research and training programme involve engineering suitable ex vivo culture environments that, by mimicking the native tendon tissue milieu (human and equine), will maintain the tenogenic phenotype of tendon derived cells and differentiate non-tendon derived cells (stem cells and dermal fibroblasts) towards the tenogenic lineage, subsequently enabling development of three-dimensional cell-assembled tissue equivalents, the clinical potential of which will be assessed in suitable preclinical models. The comprehensive Tendon Therapy Train programme will equip researchers with transferable inter- and multidisciplinary skills that will further European-based knowledge, innovation, competitiveness and leadership in the field of TESA / ATMP and ultimately enable clinical translation and commercialisation of the developed technologies.;3876965,65;3876965,64;H2020-MSCA-ITN-2015;/MSCA-ITN-ETN;NATIONAL UNIVERSITY OF IRELAND GALWAY;IE;"UNIVERSIDADE DO MINHO;STEMCELL TECHNOLOGIES SARL;THE ROYAL VETERINARY COLLEGE;TECHNOLOGIKO EKPEDEFTIKO IDRYMA IPIROU;PROXY BIOMEDICAL LIMITED;UNIVERSITEIT MAASTRICHT;SOFRADIM PRODUCTION SASU;STEMCELL TECHNOLOGIES UK LTD";"PT;FR;UK;EL;IE;NL";;1;0;0;2;0;0 206293;701923;SYRIANBORDERS;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;The Fall of a Colonial Legacy: A Modern History of Syrian Borders (1920-2015);2016-10-10;2018-10-09;;"This project aims to propose a contemporary history of Syrian borders from their origins (1920) to the present day (2015). Upon the completion of my fellowship, my main objective will be to publish a fully documented and innovative monograph on the history of the Syrian state by studying its emergence and consolidation, and by probing its colonial borders. As part of my research, I will rely on a multidisciplinary and comparative approach, using political science, sociology and, more generally, border studies. My innovative methodology will require me to conduct dozens of semi-structured interviews and to examine Syrian, French & British archives. This proposal is designed as a response to the fact that contemporary Syria – with the exception of some recent academic monographs (Thompson, 2013; Heydemann, 2013) – still lacks major research programs. The literature, mainly monodisciplinary, is even poorer when it comes to the study of borders, a field that suffers globally from theoretical weakness and the use of outdated research methods and techniques. Major studies on the Syrian borders are nonexistent. Furthermore, the field of border studies lacks a serious interdisciplinary perspective. My research will contribute to the development of the discipline. Thus, my original and innovative project will contribute to the history of contemporary Syria by analysing it through the spectrum of its borders, by bringing a multidisciplinary perspective to border studies, by producing a monograph that will include post-2011 dynamics, by prompting a series of peer-reviewed articles on Syrian borders from a comparative and interdisciplinary perspective (from 1920 to 2015), with different theoretical approaches, by contributing to the unification of a “border theory” for the Middle East, and, finally, by constituting a pioneering work on the processes of creation, stabilisation, transformation and contestation of Syrian boundaries.";183454,8;183454,8;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;UK;;;;1;0;0;2;0;0 216522;787842;ARTSOUNDSCAPES;SIGNED;H2020-EU.1.1.;ERC-2017-ADG;H2020;The sound of special places: exploring rock art soundscapes and the sacred;2018-10-01;2023-09-30;;The ARTSOUNDSCAPES project deals with sound, rock art and sacred landscapes among past hunter-gatherers and early agricultural societies around the world. The potential of sound to stimulate powerful emotions makes it a common medium for conferring places with extraordinary agency. Ethnographic and ethnohistorical sources indicate that these sites are often endowed with a sacred significance and, in many cases, they also receive special treatment, including the production of rock paintings. Despite the aural experience being an integral component of the human condition and a key element in ritual, archaeology has largely been unable to study it systematically. Rock art landscapes are no exception and, although some studies have been made, they have largely been reproached for their lack of scientific rigour and subjectivity. ARTSOUNDSCAPES will fully address this weakness by investigating the perception of sound in rock art landscapes from an interdisciplinary approach. Borrowing methods developed in acoustic engineering, the project will assess, from an objective and quantitative perspective, the acoustic properties of rock art landscapes in selected areas around the world: the Western/Central Mediterranean in Europe, Siberia in Asia, and Baja California in North America. Human experiences associated with altered or mystical states invoked by the identified special sonic characteristics of these landscapes will be further tested by exploring the psychoacoustic effects these soundscapes have on people and their neural correlate to brain activity. The project will also thoroughly survey ethnographic attitudes to sacred soundscapes based on both current premodern societies and ethnohistorical sources. The groundbreaking combination of this array of interdisciplinary approaches will facilitate the ultimate aim of the project: to propose a phenomenological understanding of sacred soundscapes among late hunter-gatherers and early agriculturalists around the world.;2239375;2239375;ERC-2017-ADG;/ERC-ADG;UNIVERSITAT DE BARCELONA;ES;;;;1;0;0;2;0;0 209618;750403;INFLAMM-ALZ;TERMINATED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;The Role of Neuroinflammation in Alzheimer’s Disease;2017-11-01;2019-10-31;;Alzheimer’s disease (AD) is a major public health problem with substantial economical and social impacts worldwide. Despite intense research, the pathological mechanisms of AD are still unclear. Under homeostasis, a delicate balance is struck between disposal of pathogenic proteins by the brain’s immune cells, microglia, and the inflammation produced by these cells. Indeed, during an acute activation, microglia are protective, but if microglia enter an over-activated state they can induce chronic inflammation through oxidative stress that in turn leads to neuronal damage. Thus, gaining data on the chain of events involved in microglial action is a prerequisite to understanding AD. This project is a large interdisciplinary collaborative effort involving well-established methods such as confocal imaging and transgenic zebrafish, with newly developed photopharmacological tools. Drs Kettunen, Gr?tli and Andréasson provide the world-leading expertise required for the project. By coordinating this project, Dr Mourabit will gain invaluable experience in biomedical research, photochemistry, project management, supervision, and the production of scientific results. The novel photoresponsive probes used here will allow for photonic in vivo de/activation of microglia, generating new information on their spatiotemporal activity, in real-time. This state-of-the-art resolution of cell-tracking and control of microglial signalling will provide innovative data on the pathology of neuroinflammation. We believe this interdisciplinary team will push the boundaries of research in AD. This project has the potential to identify new treatments for AD, and influence the direction of neurobiology. This project will create a unique career opportunity for Dr Mourabit, enabling him to crossover from an environmental background to biomedical research. The marrying of such interconnected disciplines will help Dr Mourabit set the foundations of an eclectic and vibrant research group.;173857,2;173857,2;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;GOETEBORGS UNIVERSITET;SE;;;;1;0;0;2;0;0 201491;707225;FaGEng;TERMINATED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Fashioning Georgian Englishness: Race, National Identity, and Codes of Proper Behaviour;2017-01-01;2018-12-31;;"The proposed research project ‘Fashioning Georgian Englishness: Race, National Identity, and Codes of Proper Behaviour’ examines the interconnectedness of nationality, race, and conduct within an eighteenth-century colonial perspective. The interdisciplinary project argues that race played a vital but ambiguous role in the construction of the nascent English national identity in the Georgian era (1714–1830); however, since race was a fluid and heterogeneous concept, the racial and/or national status of English subjects was constructed through the vocabulary and practices of decency, propriety, refinement, and good conduct. Articulations and practices of class- and gender-based ‘proper behaviour’ were thus used to create a naturalised English national character that had a racial foundation. The project employs an interdisciplinary methodology that combines cultural and intellectual historical methods with constructionist and postcolonial perspectives; through this approach, it examines race and national character as deeply performative, fictive constructions, created through internalising discursive knowledge. The project makes a significant and novel contribution to the history of eighteenth-century English nationalism, which has thus far ignored the importance of race for the construction of a national identity. Moreover, the questions and themes the research addresses also offer a highly fruitful point of comparison to recent processes of cultural interaction and exchange, and the structures of racism and nationalism in present-day Europe.";195454,8;195454,8;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;QUEEN MARY UNIVERSITY OF LONDON;UK;;;;1;0;0;2;0;0 220302;794705;MICROCRACK;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Micromechanics of rock fracture: enabling energy-efficient mining through next generation cracking models;2019-10-01;2021-09-30;;"Mining is a huge industry that accounts for a very significant share of global energy consumption, with rock comminution being responsible for – at least – half of the total energy expenditure. There is, consequently, a strong need to develop innovative energy-efficient mining techniques, and this proposal will focus on this major opportunity. A physically-based constitutive framework for anisotropic cracking of heterogeneous rocks will be developed, laying the scientific foundations for micromechanical modelling of rock fracture. The model will embed the mechanisms governing cracking of heterogeneous rocks in a novel and interdisciplinary approach. The complementary profile of the applicant and the host group is a strong asset, with their previous experience in micromechanics and fracture establishing the basis to successfully overcome the theoretical, numerical and experimental challenges of the project. The proposal builds upon the applicant’s background and involves new research areas, widening his competences and supporting development to academic maturity. An appropriate work plan has been programmed to achieve the scientific objectives and ensure knowledge transfer. Milestones and deliverables have been established to monitor the progress of the project implementation and pertinent corrective measures projected. A detailed dissemination strategy has been proposed to communicate findings to the general public, and to increase the impact of the research outcomes in the scientific community and engineering practice. The Cambridge Centre for Micromechanics provides an optimum environment for the project, containing the facilities required to perform the indispensable critical experiments and advanced numerical simulations. Moreover, it constitutes a unique platform to develop international, intersectoral and interdisciplinary recognition, supporting the applicant in achieving a breakthrough that will significantly impact his scientific career.";183454,8;183454,8;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;UK;;;;1;0;0;2;0;0 219804;789111;EvolvingEconomics;SIGNED;H2020-EU.1.1.;ERC-2017-ADG;H2020;Human motivation: evolutionary foundations and their implications for economics;2019-01-01;2023-12-31;;"Economics provides decision-makers with powerful tools to analyse a wide range of issues. The methodological unity of the discipline and its quest for a general understanding of market as well as non-market interactions have given the discipline great influence on policy. A core component of economics is its assumption that individuals act as if they each had some goal function that they seek to maximise, under the constraints they face and the information they have. Despite significant advances in behavioural economics, there still is no consensus as to whether and why certain preferences are more likely than others. Further progress could be made if the factors that shape human motivation in the first place were understood. The aim of this project is to produce novel insights about such factors, by establishing evolutionary foundations of human motivation.The project's scope is ambitious. First, it will study two large classes of interactions: strategic interactions, and interactions within the realm of the family. Second, to obtain both depth and breadth of insights, it will consist of four different, but inter-related, components (three theoretical and one empirical), the ultimate goal being to significantly enhance our overall understanding of the factors that shape human motivation. The methodology is ground-breaking in that it is strongly interdisciplinary. Parts of the body of knowledge built by biologists and evolutionary anthropologists in the past decades will be combined with state-of-the-art economics to produce insights that cannot be obtained within any single discipline. Focus will nonetheless be on addressing issues of importance for economists.The proposed research builds on extensive work done by the PI in the past decade. It will benefit from the years that the PI has invested in understanding the biology and the evolutionary anthropology literatures, and in contributing towards building an interdisciplinary research ecosystem in Toulouse, France";1550891,25;1550891,25;ERC-2017-ADG;/ERC-ADG;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FR;;;;1;0;0;2;0;0 219800;802940;inCITe;SIGNED;H2020-EU.1.1.;ERC-2018-STG;H2020;Seeing Citrulline: A Molecular Toolbox for Peptidyl Arginine Deiminases;2019-01-01;2023-12-31;;"Roughly 1% of the world’s population is affected by rheumatoid arthritis (RA); a devastating autoimmune disease causing cartilage destruction and bone erosion. Recent evidences suggest that dysregulation of Peptidyl Arginine Deiminase (PAD) levels are associated with the onset of the disease, leading to the production of antibodies targeting the citrullinated neoepitopes. The exact role of each of the PAD isotypes in these pathological processes is unknown and fundamental questions on the intracellular activation mechanism and substrate specificity remain unanswered. Moreover, isoform specific and high affinity enzyme inhibitors are lacking thereby not only hampering fundamental research towards each PAD isotype, but also excluding PAD as a potential therapeutic target for these diseases. This proposal is aimed at developing innovative chemical biology- and molecular tools to study PAD functioning and protein citrullination in health and disease. The work reflects my interdisciplinary experiences as well as my interest I have obtained over the last years in chemical immunology as well as my ambition to improve patients wellbeing. More detailed, I aim to 1) find unknown PAD modulators, 2) find PAD substrates, 3) find selective and high affinity PAD inhibitors using enzyme-templated inhibitor evolution as novel lead discovery strategy, 4) explore multifunctional targeted PAD ‘nanosponges’ as advanced avidity-based nanomedicine approach and 5) explore unprecedented citrulline ‘eraser’ enzymes by innovative chemical biology strategies. The workpackages described in this ambitious and highly interdisciplinary proposal deliver high-end molecules and methods that can be used to answer fundamental (conflicting) questions on citrullination and PAD biology. Moreover, possible molecular leads and advanced therapeutic insights are provided thereby centring PAD as therapeutic target for citrulline-mediated autoimmune diseases such as RA.";1500000;1500000;ERC-2018-STG;/ERC-STG;STICHTING KATHOLIEKE UNIVERSITEIT;NL;;;;1;0;0;2;0;0 219199;824087;EOSC-Life;SIGNED;H2020-EU.1.4.1.1.;INFRAEOSC-04-2018;H2020;Providing an open collaborative space for digital biology in Europe;2019-03-01;2023-02-28;;"EOSC-Life brings together the 13 Biological and Medical ESFRI research infrastructures (BMS RIs) to create an open collaborative space for digital biology. It is our joint response to the challenge of analysing and reusing the prodigious amounts of data produced by life-science. Managing and integrating this data is beyond the capabilities of most individual end-users and institutes. By publishing data and tools in a Europe-wide cloud EOSC-Life aims to bring the capabilities of big science projects to the wider research community. Federated user access (AAI) will allow transnational resource access and authorisation. EOSC-Life establishes a novel access model for the BMS RI: through EOSC scientists would gain direct access to FAIR data and tools in a cloud environment available throughout the European Research Area. EOSC-Life will make BMS RIs data resources FAIR and publish them in the EOSC following guidelines and standards (e.g. EDMI). Overall this will drive the evolution of the RI repository infrastructure for EOSC and integration of the BMS RI repositories. EOSC-Life will implement workflows that cross disciplines and RI boundaries and address the needs of interdisciplinary science. Through open hackathons and bring-your-own-data events we will co-create EOSC-Life with our user communities , providing a blueprint for how the EOSC supports wide-spread and excellent data-driven life science research. EOSC-Life will address the data policies needed for human research data under GDPR. Interoperable provenance information describe history of sample and data to ensure reproducibility and adherence to regulatory requirements. The goal of the EOSC-Life project is to make sure that life-scientists can find, access and integrate life-science data for analysis and reuse in academic and industrial research. EOSC-Life will transform European life-science by providing an open, continent-scale, collaborative and interdisciplinary environment for data science.";23745996,25;23745996,25;H2020-INFRAEOSC-2018-2;/RIA;EUROPEAN MOLECULAR BIOLOGY LABORATORY;DE;"ACADEMISCH ZIEKENHUIS LEIDEN;ECRIN EUROPEAN CLINICAL RESEARCH INFRASTRUCTURE NETWORK;EATRIS ERIC;THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE;Masarykova univerzita;THE UNIVERSITY OF MANCHESTER;INSTRUCT-ERIC;OULUN YLIOPISTO;STICHTING VU;FORSCHUNGSZENTRUM JULICH GMBH;BIOBANKS AND BIOMOLECULAR RESOURCESRESEARCH INFRASTRUCTURE CONSORTIUM(BBMRI-ERIC);KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW;UNIVERSITEIT GENT;HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH;USTAV MOLEKULARNI GENETIKY AKADEMIE VED CESKE REPUBLIKY VEREJNA VYZKUMNA INSTITUCE;FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.;NACIONALNI INSTITUT ZA BIOLOGIJO;UNIVERSITY OF DUNDEE;ALBERT-LUDWIGS-UNIVERSITAET FREIBURG;UNIVERSITAT DE VALENCIA;UNIVERSITA DEGLI STUDI DI TORINO;UNIVERSITEIT MAASTRICHT;EUROPEAN RESEARCH INFRASTRUCTURE ON HIGHLY PATHOGENIC AGENTS;AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS;CONSORZIO INTERUNIVERSITARIO RISONANZE MAGNETICHE DI METALLO PROTEINE;EUROPEAN MARINE BIOLOGICAL CENTER EUROPEAN RESEARCH INFRASTRUCTURE CONSORTIUM;CENTRE EUROPEEN DE RECHERCHE EN BIOLOGIE ET MEDECINE;CONSIGLIO NAZIONALE DELLE RICERCHE;CENTRO DE CIENCIAS DO MAR DO ALGARVE;CHARITE - UNIVERSITAETSMEDIZIN BERLIN;IRCCS OSPEDALE POLICLINICO SAN MARTINO;BIOMEDICAL SCIENCES RESEARCH CENTER ALEXANDER FLEMING;FUNDACIO INSTITUT MAR D INVESTIGACIONS MEDIQUES IMIM;UNIVERSITA' DEGLI STUDI DI MILANO-BICOCCA;EUROPEAN INFRASTRUCTURE OF OPEN SCREENING PLATFORMS FOR CHEMICAL BIOLOGY EUROPEAN RESEARCH INFRASTUCTURE CONSORTIUM (EU-OPENSCREEN ERIC);THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE;ABO AKADEMI;VLAAMS INSTITUUT VOOR DE ZEE VZW;UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA;INFRAFRONTIER GMBH;UNIVERSIDAD DE VIGO;CSC-TIETEEN TIETOTEKNIIKAN KESKUS OY;SORBONNE UNIVERSITE";"NL;FR;UK;CZ;FI;DE;AT;BE;SI;ES;IT;PT;EL";;1;0;0;2;0;0 220264;823826;BE-ARCHAEO;SIGNED;H2020-EU.1.3.3.;MSCA-RISE-2018;H2020;BEyond ARCHAEOlogy: an advanced approach linking East to West through science, field archaeology, interactive museum experiences;2019-02-01;2023-01-31;;"Although approaches combining archaeology and archaeometry in the investigation of past records are presently well established, recent technological advances, especially the new IT tools, push for a general update of the consolidated procedures. Researchers and professionals need to develop expertise and skills under new perspectives, to enable a new trans-disciplinary storytelling from the archaeological site to the museum display. BE-ARCHAEO launches a trans-disciplinary approach in the investigation of past social experience registered at archaeological sites, where the involvement of IT experts within an on-the-field interplay between archaeologists and an exhaustive set of interlinked archaeometry experts will enable R&I and will expose the involved individuals to a truly interdisciplinary and trans-sectoral environment, thus improving their career perspectives significantly. The participants, belonging to various domains of archaeology, archaeometry, museology and IT, will commit skills and instruments to the project for performing cutting-edge scientific investigations and for developing the most capturing interactive museum experiences. The Japanese partners will give the opportunity of developing the BE-ARCHAEO approach in a new area of archaeological excavation and will give access to their archaeological collections for investigations and analysis. Bidirectional knowledge transfer among the participants - set up on the tailored Japanese case–study - will lead to the development of cultural heritage professionals with a trans-disciplinary vision of the archaeological records; new procedures for integrated archaeology and archaeometry; new IT tools for storing/retrieving interdisciplinary data and for communicating to the general public the new knowledge stemming by combining archaeology and science. Intersectoral interactions and connections with the stakeholders will keep the research tightly linked to the needs of the final users.";823400;708400;H2020-MSCA-RISE-2018;/MSCA-RISE;UNIVERSITA DEGLI STUDI DI TORINO;IT;"TECNART SRL;P. SOTIROPOULOS-SP. MAROULAKIS OE;INTERNATIONAL RESEARCH INSTITUTE FOR ARCHAEOLOGY AND ETHNOLOGY;Faculdade de letras da Universidade de Lisboa;Visual Dimension bvba";"IT;EL;PT;BE";;1;0;0;2;0;0 219579;823862;DIGITENS;SIGNED;H2020-EU.1.3.3.;MSCA-RISE-2018;H2020;DIGITal ENcyclopedia of European Sociability;2019-01-01;2021-12-31;;"The Digital Encyclopaedia of European Sociability (DIGITENS) project will produce the first open-access digital encyclopaedia and anthology of sociability in Europe throughout the long-eighteenth century. The purpose of the DIGITENS project is to build an original framework for understanding the interactions, tensions, limits and paradoxes underlying European models of sociability and to reflect on the following question: Can the emergence and formation of European models of sociability be traced throughout the long eighteenth century (1650-1850)? Drawing upon the expertise of international members from different disciplines and national traditions, the project will create a toplevel interdisciplinary network and facilitate intersectoral communication between its academic and non-academic partners. The eight international universities will work together with the Biblioth?que Nationale de France, Musée Cognacq-Jay in France, and The National Archives in Great Britain, allowing members to explore how understandings of sociability might be enhanced through dialogue, international collaboration, and digital technology, developing a broader contextualisation of the research into European sociability. As the first digital encyclopaedia of its kind, the expected impact of the resource will not only benefit researchers, but anyone interested in the history of European models of sociability. The project is not, however, of purely historical or academic interest. Through the implementation of outreach events, workshops and the production of the accessible digital platforms, the DIGITENS team will promote a wide investigation of the value of eighteenth century principles in twenty-first-century private and public lives throughout Europe. The interdisciplinary and international aspects of the DIGITENS project, and coherent methodology, are innovative, and the scope broad and ambitious.";299000;299000;H2020-MSCA-RISE-2018;/MSCA-RISE;UNIVERSITE DE BRETAGNE OCCIDENTALE;FR;"THE NATIONAL ARCHIVES;BIBLIOTHEQUE NATIONALE DE FRANCE;PARIS MUSEES;UNIVERSITE PARIS 13;UNIWERSYTET KAZIMIERZA WIELKIEGO;THE UNIVERSITY OF WARWICK;UNIVERSITAET GREIFSWALD;SORBONNE UNIVERSITE";"UK;FR;PL;DE";;1;0;0;2;0;0 218319;823883;NanoPol;SIGNED;H2020-EU.1.3.3.;MSCA-RISE-2018;H2020;Soft Biocompatible Polymeric Nanostructures: A Toolbox for Novel Generation of Nano Pharmaceuticals in Ophthalmology;2019-03-01;2023-02-28;;We propose a research and innovation project that aims to develop a rational, knowledge-based toolbox for the fabrication of (1) biodegradable and biocompatible associating (gel-forming) polymers, (2) nanogels and (3) nanoparticles tailored as multifunctional therapeutic agents in ophthalmological applications. We seek for novel methods to replace currently used approaches with biocompatible and biodegradable synthetic/natural polymers. Macromolecules of increasingly complex architectures including block, graft and star-like polymers will be explored with respect to their ability to build up transient networks or nanoparticles with well-controlled rheological and structural properties and targeted performance. Profound understanding of the relation between architectural complexity and properties of the macromolecules is crucial for the fabrication of functional polymer-based materials for biomedicine and will greatly enhance the competitiveness of Europe in the field. Such conceptual understanding can only be achieved based on a rational interdisciplinary approach, in which theory and simulations guide experiments. Our work plan includes the design, synthesis and characterization of novel macromolecular architectures dictated by theoretical and simulation outcomes on the properties of the materials, followed by toxicity and in vitro/in vivo testing of the materials/structures and industrial feasibility studies. The macromolecular assemblies will be investigated as complex carriers enabling (1) prolonged retention in the eye and (2) controlled ocular drug release under external stimuli (i.e. temperature, light, pH). The synergy resulting from the cooperation between world-leading in their respective fields academic groups and companies though the effective secondments plan will provide a unique interdisciplinary research and training environment that will allow to address unmet challenges in the area and will ensure European leadership in cutting-edge technologies.;1035000;685400;H2020-MSCA-RISE-2018;/MSCA-RISE;PANEPISTIMIO KRITIS;EL;"HELSINGIN YLIOPISTO;THE UNIVERSITY OF READING;USTAV MAKROMOLEKULARNI CHEMIE AV CRVVI;BIONAVIS OY;NANOMATERIALES Y POLIMEROS SL;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS";"FI;UK;CZ;ES;FR";;1;0;0;2;0;0 218461;813781;BestTreat;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2018;H2020;BestTreat – Building a Gut Microbiome Engineering Toolbox for In-Situ TherapeuticTreatments for Non-alcoholic Fatty Liver Disease;2018-09-01;2022-08-31;;BestTreat fosters education of ESRs in a project to uncover microbiome signatures for risk prediction and monitoring of NAFLD and to contribute to the development of therapeutic treatments based on metabolically beneficial microbial consortia. It trains 15 ESRs at world-leading academic institutions and companies, thus forming strong interdisciplinary links between industry, life and medical sciences, and end-users. BestTreat aims to train a new generation of highly qualified ESRs with entrepreneurial competencies in modern Life Sciences through state-of-the-art research projects. The projects focus on the identification and functional characterization of microbial consortia that contribute to metabolic control, and the application of this knowledge to develop novel leads for drug discovery and therapies for NAFLD. The new field on microbiome based therapeutics requires highly skilled scientists with interdisciplinary knowledge on medicine, systems biology and computer science, as well as hands-on experience with several types of tissue samples and model organisms that can optimally translate their research findings into sustainable improvements in clinical practice. BestTreat overcomes current barriers by establishing a strong, multidisciplinary and inter-sectoral training network, developing technologies tailored to solve key questions in human metabolism, microbiology and bioinformatics. The BestTreat programme will exploit recent developments in high-throughput and genome-wide screening technologies, combine these with modern molecular cell biology and systems biology approaches and ultimately translate the data into new leads for the discovery of live biotherapeutics. This specific cross-disciplinary training program will educate young scientists to the next level needed to advance this research field for the upcoming decennium. The training programme will be complemented with a complete set of transferable skills.;4134155,76;4134155,76;H2020-MSCA-ITN-2018;/MSCA-ITN-ETN;LEIBNIZ-INSTITUT FUR NATURSTOFF-FORSCHUNG UND INFEKTIONSBIOLOGIE EV HANS-KNOLL-ISTITUT;DE;"AFEKTA TECHNOLOGIES LTD;DANMARKS TEKNISKE UNIVERSITET;CHR. HANSEN A/S;CLINICAL-MICROBIOMICS AS;RIJKSUNIVERSITEIT GRONINGEN;ITA-SUOMEN YLIOPISTO;Academisch Medisch Centrum bij de Universiteit van Amsterdam";"FI;DK;NL";;1;0;0;2;0;0 218501;812868;CReaNet;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2018;H2020;Chemical Reaction Networks: signal amplification, spatiotemporal control, and materials;2019-04-01;2023-03-31;;Chemical reaction networks are ubiquitous in living systems, and hold great promise for the generation of future ultrasensitive sensors, for finding advanced production schemes towards high value chemicals and for enabling future autonomous and adaptive materials. To become a technology leader in this area, it is imperative for EU to invest in i) training highly skilled researchers and ii) conducting research interfacing fundamental sciences and technologically relevant applications. This ETN focuses on strengthening EU’s innovation capacity via an integrative EU doctoral training on “Chemical Reaction Networks: signal amplification, spatiotemporal control, and materials”. It brings together an interdisciplinary team of 6 proven academic experts and 4 non-academic partners to inspire and educate a new generation of ESRs (early stage researchers) to become leaders in this emerging research area of chemical reaction networks – a subject which is not specifically taught at EU universities. We provide the ESRs with a comprehensive, structured, interdisciplinary and intersectorial training, and bridge fundamental research and applications with a cutting-edge research program. The objective of the research program is to unravel design principles for chemical reaction networks, find pathways to modulate them from the outside, and develop them towards applications for ultrasensitive sensors and autonomous materials with time-programmed operation. The close interaction between academia and private sector will ensure a multifaceted view, and a swift transfer of fundamental discoveries to applications. The intersectorial partner setting, together with the balanced training of research-related and transferable skills, will enhance the career perspectives of the ESRs in both the academic and non-academic sectors. This ETN will form ESRs with highest levels of creativity, innovation capabilities and entrepreneurial mindsets, and thus promote EU leadership in nanosciences.;4076237,52;4076237,52;H2020-MSCA-ITN-2018;/MSCA-ITN-ETN;UNIVERSITE DE STRASBOURG;FR;"THE UNIVERSITY OF SHEFFIELD;WEIZMANN INSTITUTE OF SCIENCE;ELVESYS SAS;ALBERT-LUDWIGS-UNIVERSITAET FREIBURG;IBM RESEARCH GMBH;NANOTEMPER TECHNOLOGIES GMBH;TECHNISCHE UNIVERSITEIT DELFT;Netherlands Forensic Institute;CHALMERS TEKNISKA HOEGSKOLA AB";"UK;IL;FR;DE;CH;NL;SE";;1;0;0;2;0;0 203826;703493;NEUROBUKIMI;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Affective neurocognitive model for the ‘Uncanny Valley’;2016-08-01;2018-07-31;;The Uncanny Valley hypothesis (UV), proposed already 45 years ago, suggests that too humanlike robots or other artificial characters will elicit feelings of eeriness (Jpn. ‘bukimi’) in human observers. Existing psychological and neuroimaging studies have focused on the humanlikeness dimension of UV but neglected its emotional experience, which was at the heart of the original hypothesis. This interdisciplinary project will develop a thorough model for the emotional dimension of UV, consisting both of subjective verbal descriptions and observed neuronal activation patterns. A series of neuroimaging experiments will be carried out at the Brain and Emotion Laboratory of Maastricht University (UM): the first experiment will test the neuronal correlates of negative emotions elicited by semi-realistic virtual characters, and the second experiment will take a step beyond the original UV hypothesis by comparing the neuronal activation patterns of real and virtual emotional expressions. A self-report questionnaire for verbalizing the emotional experience of UV will be developed during a secondment period at Eindhoven University of Technology (Tu/e). By explicating the emotional experience of UV and by providing open tools for both research and industry, this project will be an important turning point for the future development of all humanlike technologies. Consistently, direct and concrete contacts with the animation industry are planned during the project. My supervisor Prof. de Gelder from UM is one of the thought leaders in the field of affective cognitive neuroscience, and my secondment supervisor Prof. Ijsselsteijn from Tu/e is renowned for his work in human-technology interaction. I am an experienced researcher with a dual background in both of these disciplines, as well as specific background in UV topic. This interdisciplinary synergy will maximize this project’s impact on the European society and help establish my position as a leading independent scientist.;177598,8;177598,8;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;UNIVERSITEIT MAASTRICHT;NL;;;;1;0;0;2;0;0 197121;664584;RISE;SIGNED;H2020-EU.4.a.;WIDESPREAD-1-2014;H2020;Research Centre in Interactive Media, Smart Systems and Emerging Technologies;2015-06-01;2016-05-31;;"In line with WIDESPREAD-2014-1 TEAMING, this proposal puts forward the vision for establishing a “Research centre on Interactive media, Smart systems and Emerging technologies” (RISE). RISE aims to become a Centre of Excellence and a hub across the three continents bordering Cyprus, facilitating thus the local scientific, technological, and economic growth of the region. The proposal identifies the potential of Interactive Media to bring together several scientific areas, yielding applications in the priority areas of the Smart Specialisation Strategy of Cyprus. Therefore, research in RISE integrates the Visual Sciences, Human Factors and Design, and Communications and Artificial Intelligence, in a tight synergy that provides a unique interdisciplinary research perspective that emphasizes an “Inspired by Humans, Designed for Humans” philosophy. To support the implementation of the research and innovation agenda of RISE, the proposal puts forward the a consortium coordinated by the Nicosia Municipality, the largest regional authority of Cyprus with extensive experience in managing large projects and commitment in establishing and supporting an innovation ecosystem in Nicosia, along with all three public universities of Cyprus. The four local partners will contribute their research, infrastructure, and financial potential for the establishment of RISE and with guidance by two Experienced Partners (MPI and UCL) with unequivocal scientific excellence and demonstrated success in running Centres of Excellence, aim to establish a sustainable Centre of Excellence in Cyprus. With the long-term sustainable growth of RISE in mind, the proposal designates an administrative structure for the Centre to facilitate its interdisciplinary view of research, its outreach perspective towards human users and businesses, and its multi-institutional composition.";476427;476427;H2020-WIDESPREAD-2014-1;/SGA-CSA;LEFKOSIA MUNICIPALITY;CY;"TECHNOLOGIKO PANEPISTIMIO KYPROU;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;UNIVERSITY COLLEGE LONDON;ANOIKTO PANEPISTIMIO KYPROU (OPEN UNIVERSITY OF CYPRUS);UNIVERSITY OF CYPRUS";"CY;DE;UK";;1;0;0;2;0;0 194831;653056;EMEHOC;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Enriched Minimal Expressivism and Higher-Order Concepts;2015-10-01;2017-09-30;;"One (unum), True (verum), and Good (bonum), the Medieval transcendentals, are concepts that philosophers have always kept at the centre of their concern, as has occurred with logical notions such as therefore, epistemic notions such as knowledge and belief, and deontic notions such as ought. And for good reasons. The meaning of these concepts is complex, and language sciences have needed a sophisticated degree of development to be able to cope with this issue. All these notions encode what we now call “higher-order concepts”. The defining characteristic of higher-order concepts is that they are predicative notions that have other predicables (including 0-adic predicables, i.e. propositions) as arguments. Logical constants, quantifiers, and alethic, epistemic, and deontic modalities belong to the general class of high-order concepts. EMEHOC aims at developing a unified and comprehensive treatment of higher-order concepts, Enriched Minimal Expressivism, which benefits from the several insights that philosophers have put forward related to some particular sets of them, and also of the latest linguistic proposals on procedural and non-truth-conditional meaning. EMEHOC will develop the first-ever general theory of higher-order concepts. To date, philosophers and linguists have given some useful insights on them but EMEHOC will be the first to examine their functioning from an interdisciplinary perspective. EMEHOC’S impact will reach any areas of knowledge in which accurate discourse and precise argumentation are essential. This includes ethics and political theory, and in general public and scientific uses of language. EMEHOC will use a collaborative methodology that will contribute to the emergence of new, promising interdisciplinary areas, according to the objectives of the EU Framework Programme for Research and Innovation (Horizon 2020), avoiding duplications and maximizing resources.";195454,8;195454,8;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;UNIVERSITY COLLEGE LONDON;UK;;;;1;0;0;2;0;0 196899;654857;VirtualPatients;CLOSED;H2020-EU.1.3.2.;MSCA-IF-2014-GF;H2020;Effective Clinical reasoning in Virtual Patients;2015-07-01;2017-12-31;;"The European Commission estimates in the report 'Patient Safety and Quality of Care' (2014)1 that each year 8 - 12% of hospitalized patients suffer from adverse events, including errors in diagnosis. One reason for the occurrence of such errors is a lack of clinical reasoning skills, a core competency that medical students have to learn during their studies (Norman 2005, Scott 2009). Clinical reasoning is often taught in face-to-face courses such as bedside-teaching, problem-based tutorials or during internships. Since the early nineties virtual patients (VPs) became more and more important in medical education to teach clinical reasoning skills (Cook 2009). The knowledge gap this project addresses was raised by Cook et al. (2009, 2010) and, until know, remains unaddressed. He concluded that there is no evidence how VP design variations influence clinical reasoning acquisition and that it is not fully understood how VPs teach clinical reasoning and how this process could be improved. Therefore, in this project research will be undertaken to develop and assess an effective clinical reasoning tool to be embedded into VPs, and create guidelines on how to implement the tool based on the outcomes of an interdisciplinary grounded theory approach. The success of the project builds on the applicant's strong expertise in creating, integrating, and researching VPs, as well as on her interdisciplinary background in medicine, medical education research, and computer science, which enables her to manage all aspects of the project. The project will have a major impact on the applicant's career development, enabling her to become an independent researcher and ultimately establish her own research group within the field of virtual patients. Such a detailed elaboration of clinical reasoning in VPs will improve students' diagnostic skills potentially leading to a reduction of diagnostic errors, avoiding unnecessary treatment and pain for patients and reducing healthcare costs.";199828,2;199828,2;H2020-MSCA-IF-2014;/MSCA-IF-GF;LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN;DE;;;;1;0;0;2;0;0 216032;771057;WELL-BEING;SIGNED;H2020-EU.1.1.;ERC-2017-COG;H2020;"The dynamics underlying Well-being; Understanding the Exposome-Genome interplay";2018-06-01;2023-05-31;;"In light of major demographic trends, building and maintaining health and well-being amongst citizens is one of the most important societal challenges European countries face. People who feel well, function better, are less susceptible to mental illness, and thus are better able to retain competitive advantage and expand human capital. People who feel well also facilitate social capital by enjoying stronger and more-lasting relationships. Consequently, maintaining, facilitating, and building well-being (WB) would not only improve individual (health) outcomes, but also reduce economic and health care burdens. To sustainably facilitate and build WB, thorough understanding of its underlying dynamics, especially the interplay between an individual’s genetic makeup, epigenetic make-up, and (social) environmental exposure, is crucial. In this project, I will cross disciplinary boundaries to initiate the urgently needed integration of multiple layers of influence in the study of WB. The key objectives are to (1) identify, quantify, and integrate static and dynamic environmental and social exposures to build the well-being exposome, (2) understand the multi-layer interplay of the genome, the epigenome, and the exposome, and (3) integrate the empirical findings into a novel comprehensive framework of WB. I will employ an interdisciplinary approach, using association, real-life, and network methodology to assess the dynamics underling WB. To apply these state-of-the-art techniques, I will bring together longitudinal twin-family data, molecular genetic data, and big data from satellite positioning (GPS), bluetooth beacons, geographical information systems (GIS), ambulatory assessment, and social network linkage. This project will mark a shift in scientific approach and enables the development of interdisciplinary academic theories and health, social, and economic policies to maintain, facilitate, and build WB to withstand our demanding and rapidly changing world.";1999722;1999722;ERC-2017-COG;/ERC-COG;STICHTING VU;NL;;;;1;0;0;2;0;0 218626;813883;HERILAND;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2018;H2020;Cultural HERItage and the planning of European LANDscapes;2019-04-01;2023-03-31;;European countries have a long and successful history of conserving their rich heritage and landscape assets in town and country, and of capitalising on them culturally and economically. Throughout the 20th century, great progress was made in creating structures and promulgating principles to guide heritage and landscape conservation, but as the 21st century proceeds, society is challenged by new far-reaching changes. These include various forms of migration, greater digital connection, environmental degradation and climate change, shifts in the public/private balance in society at large, and a renewed pressure for growth. Confronted with such a fast-changing context, heritage management needs new ideas, tools and training to ensure that interdisciplinary, research-based heritage, landscape management and spatial planning are positively integrated with business activity, development and democratic decision making. Through HERILAND, a consortium of 7 key academic and non-academic organizations, with 21 partners in civil society and business, aims to empower a new generation of academics, policy makers, practitioners, professionals and entrepreneurs. Our research design positions heritage in the frame of five transformation processes which we identify as key challenges to the heritage management of the 21st century: The Spatial Turn, Democratisation, Digital Transformations, Shifting Demographies and Contested Identities, and Changing Environments. Using this framework, 15 PhD researchers will be provided with advanced training combining theoretical and instrumental knowledge in a series of research seminars, living labs and secondments with our public and private partners. By doing this, HERILAND will establish a new pan-European, trans-national, interdisciplinary and cross-sectoral research and training standard, which will be codified in a HERILAND Handbook for Heritage Planning and instrumentalised through an ongoing HERILAND College for Heritage Planning.;4003368,84;4003368,84;H2020-MSCA-ITN-2018;/MSCA-ITN-ETN;STICHTING VU;NL;"NARODOWA FUNDACJA OCHRONY SRODOWISKA;UNIVERSITY OF NEWCASTLE UPON TYNE;UNIVERSITA DEGLI STUDI ROMA TRE;BEZALEL ACADEMY OF ARTS AND DESIGN;GOETEBORGS UNIVERSITET;TECHNISCHE UNIVERSITEIT DELFT";"PL;UK;IT;IL;SE;NL";;1;0;0;2;0;0 218505;813869;BioImplant ITN;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2018;H2020;European Training Network to develop Improved Bioresorbable Materials for Orthopaedic andVascular Implant Applications;2019-01-01;2022-12-31;;BioImplant ITN is a European Industrial Doctorate (EID) programme that will provide world-class multidisciplinary training to a new generation of high-achieving ESRs in the area of medical device development. A well-balanced consortium of academic, industry and clinical partners has been assembled to deliver the training programme, spanning a number of EU countries and industry sectors to promote international, interdisciplinary and inter-sectoral aspects of ESR skill development. The programme vision of the BioImplant ITN is to deliver technical, interdisciplinary and transferrable skills training to the ESR community all areas of the medical device development Supply Value Chain. The BioImplant ITN programme will develop improved bioresorbable materials and implement them in orthopaedic and vascular implant applications. Bioresorbable materials are rapidly gaining traction in soft and hard tissue medical implants, with both polymer- and metal-based resorbable materials having been developed for medical device applications. However, major issues relating to their poor mechanical properties and rapid degradation behaviour have limited their application. The research programme of the BioImplant ITN will address these issues by (i) targeting new processing solutions to enhance the mechanical behaviour of bioresorbable polymers and (ii) integrate high stiffness magnesium- and ceramic-based reinforcements with polymers to produce novel hybrid/composite materials with optimised functional performance. The development of these innovative biomaterials will represent a major advancement on the current state-of-the-art in bioresorbable materials and maximise commercial potential in vascular and orthopaedic applications. Furthermore, the comprehensive skillset delivered by the programme will enhance career development and employability of ESRs within the Medical Technology sector and promote their development into leading innovators in the European Medical Technology sector.;3316930,56;3316930,56;H2020-MSCA-ITN-2018;/MSCA-ITN-EID;NATIONAL UNIVERSITY OF IRELAND GALWAY;IE;"FUNDACION IMDEA MATERIALES;RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN;BOSTON SCIENTIFIC LIMITED;THE QUEEN'S UNIVERSITY OF BELFAST;ITA TECHNOLOGIETRANSFER GMBH;VASCULAR FLOW TECHNOLOGIES LIMITED;MEOTEC GMBH & CO KG";"ES;DE;IE;UK";;1;0;0;2;0;0 218449;813844;CAFE;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2018;H2020;Climate Advanced Forecasting of sub-seasonal Extremes;2019-03-01;2023-02-28;;"Climate extremes such as heat waves or tropical storms have huge social and economic impact. The forecasting of such extreme events at the sub-seasonal time scale (from 10 days to 3 months) is challenging. Since the atmosphere and the ocean are coupled systems of enormous complexity, in order to advance sub-seasonal predictability of extreme events, it is crucial to train a new kind of interdisciplinary top-level researchers. CAFE research is structured in three WP: Atmospheric and oceanic processes, Extreme events and Tools for predictability, and brings together an interdisciplinary team of scientists. Objectives: Study of the relation between RWPs and the large scale environment, and the resulting limit of predictability; Statistical characterization of MJO events, dependence on climatic factors, and simple modelling to evaluate predictability; Development of diagnosis tools for identification and tracking of the MJO, blocking, waves and oceanic structures; Analysis of climatic changes in weather patterns and their relation with new climatic phenomena and extreme events in Europe; Estimation of probabilities for severe damages due to extreme events associated to ENSO; Validation of the hypothesis of cascades of extreme events and effects of a non-stationary climate; Estimation of exceedance probabilities for intensity of severe atmospheric events, including windstorms and hurricanes; Assessment of the response of extreme weather events for different levels of stabilized global warming and comparison with their response to internal modes of climate variability; Development of a procedure to improve the predictability of the onset of monsoon; Advanced statistical analysis of dynamic associations between SSS and extreme precipitation events; Study of predictability of large-scale atmospheric flow patterns over the Mediterranean connected to extreme weather; Systematic quantification of the predictability potential of a SWG of analogues of atmospheric circulation.";3155771,88;3155771,88;H2020-MSCA-ITN-2018;/MSCA-ITN-ETN;Consorci Centre de Recerca Matematica;ES;"UNIVERSIDAD DE LA REPUBLICA;AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS;POTSDAM INSTITUT FUER KLIMAFOLGENFORSCHUNG;UNIVERSITAT POLITECNICA DE CATALUNYA;EUROPEAN CENTRE FOR MEDIUM-RANGE WEATHER FORECASTS;METEO-FRANCE;ARIA TECHNOLOGIES SA;TECHNISCHE UNIVERSITAET BERGAKADEMIE FREIBERG;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV";"UY;ES;DE;UK;FR";;1;0;0;2;0;0 218415;812830;HealthAge;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2018;H2020;Joint Training and Research Program on Lifespan Regulation Mechanisms in Health and Disease;2019-05-01;2023-04-30;;"Aging is an inexorable homeostatic failure of complex but largely unknown aetiology that leads to increased vulnerability to disease with enormous consequences on the quality of individual lives and the overall cost to society. Although, aging is driven by limitations in somatic maintenance, it is also subject to regulation by evolutionarily highly conserved molecular pathways. Indeed, macromolecular damage may drive the functional decline with aging; however, a battery of conserved, longevity assurance mechanisms may set the pace on how rapidly damage builds up and function is lost over time. Human efforts over the last centuries have succeeded in substantially lengthening lifespan, allowing aging to become a common feature of western societies. However, The discouraging complexity of the aging process, the noticeable lack of tools to study it, and a shortage of experimentally tractable model systems have made it significantly challenging to unravel the molecular basis of the processes that cause loss of bodily functions and degeneration of cells and tissues with advancing age. HealthAge was carefully designed to create a joint European program of excellence in training and research with a core intellectual focus on the functional role of “Lifespan Regulation Mechanisms in Health and Disease”. To tackle this, HealthAge combines top-level, state-of-the-art and interdisciplinary research skills that range from basic molecular mechanisms and ‘omics’ level understanding to translational research and clinical applications. This interdisciplinary strategy will allow us to gain functional insight into the fundamental mechanisms regulating longevity as well as to develop a series of rationalized intervention strategies aimed at counteracting age-related diseases.";3940624,08;3940624,08;H2020-MSCA-ITN-2018;/MSCA-ITN-ETN;FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS;EL;"KLINIKUM DER UNIVERSITAET ZU KOELN;UNIVERSITAT BASEL;GENEVIA TECHNOLOGIES OY;ACADEMISCH ZIEKENHUIS GRONINGEN;ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE;UNIVERSITA DEGLI STUDI DI PADOVA;FUNDACIO INSTITUT DE RECERCA BIOMEDICA (IRB BARCELONA);PROTATOUANS - ETAIREIA EREYNAS VIOTECHNOLOGIAS MONOPROSOPI ETAIREIA PERIORISMENIS EYTHINIS;LXREPAIR;TEL AVIV UNIVERSITY;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;AMAZENTIS SA";"DE;CH;FI;NL;IT;ES;EL;FR;IL";;1;0;0;2;0;0 218022;814177;LAST-JD-RIoE;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2018;H2020;Law, Science and Technology Joint Doctorate: Rights of the Internet of Everything;2019-04-01;2023-03-31;;"Internet of Everything (IoE) is one of the major technological trends, going beyond the ongoing Internet of Things era focused only on connecting devices. IoE looks at the connection of devices, persons and data via processes: “IoE connects the unconnected with ever-smarter technology. It brings people together with process, data, and things.” If on the one hand it is considered as a huge opportunity estimated at 19b$ it presents new complexities and risks for our life and economy. The big data is an essential pillar of the IoE . Thus, including more explicitly persons and data concerning them, IoE cannot be limited to engineering and computer science, but is a topic that needs to be investigated with scientific interdisciplinary researches under different perspectives: technical, legal, economical, ethical, philosophical point of view: it “involves a complex and evolving set of technological, social, and policy considerations across a diverse set of stakeholders.” Privacy, Intellectual Proprietary Rights, Data Ownership, Super-control of people behavior, Fundamental Rights, Ethical principles are critical issues that could determine the success of IoE in the market . Algorithms which are at the core of the devices all around us, expected to be tens of billions in 2020, must be governed. IoE is already entering the H2020 work programme even if only the IoT is mentioned in the calls. The attention to nontechnological aspects is reflected in the H2020 objectives ICT-35-2016 of LEIT and REV-INEQUAL-09-2017 of SC5 focus on the need of including SSH sciences for a critical analysis of the problems raised by pervasive technologies. However, if research projects are a way to face these problems, the needed competences are lacking, since they are highly interdisciplinary and, from the legal point of view, they require an international perspective. For these reasons we present a MSCA-ITN European Joint Doctorate proposal.";3834322,92;3834322,92;H2020-MSCA-ITN-2018;/MSCA-ITN-EJD;ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA;IT;"MYKOLO ROMERIO UNIVERSITETAS;UNIVERSITAT WIEN;UNIVERSITA DEGLI STUDI DI TORINO;UNIVERSITE DU LUXEMBOURG;UNIVERSITAT AUTONOMA DE BARCELONA;KATHOLIEKE UNIVERSITEIT LEUVEN;UNIVERSIDAD POLITECNICA DE MADRID;GOTTFRIED WILHELM LEIBNIZ UNIVERSITAET HANNOVER";"LT;AT;IT;LU;ES;BE;DE";;1;0;0;2;0;0 218498;805550;FluidKnowledge;SIGNED;H2020-EU.1.1.;ERC-2018-STG;H2020;How evaluation shapes ocean science. A multi-scale ethnography of fluid knowledge.;2019-03-01;2024-02-29;;"New forms of evaluation are reconfiguring science in ways we are only beginning to understand. Through the rich case of ocean science, this project addresses a key challenge in social-scientific research regarding how evaluations are implicated in scientific understandings of the world. Ocean science is increasingly multivalent. Not only is it expected to contribute to a more systemic understanding of the ocean as an ecosystem, it is also called on to analyze environmental effects of climate change, and help fight effects of intensified exploitation. At the same time, it operates in a highly research-focused and efficiency-oriented academic system whose norms partly work against societal relevance. The ambition of FluidKnowledge is to 1) investigate how research agendas are shaped in ocean scientific research; 2) analyze how the value of ocean science is enacted in European and national science policy contexts; 3) develop concepts on the basis of the outcomes of 1) and 2), to theoretically grasp how research evaluation shapes knowledge making. Ocean science provides a planet-critical research site in which to analyze how steering efforts toward interdisciplinary engagement and societal relevance relate to other norms and criteria of scientific quality (e.g. excellence) in actual practice. This project creates a new interface between longitudinal scientometric analysis and rich ethnographic studies. This paves the way for a new interdisciplinary field. A second contribution is conceptual. Whereas many evaluation experts treat the heterogeneity of practice as a problem, I engage such heterogeneity as a resource. The project will build theory that encourages a more comprehensive understanding of how evolving evaluation and knowledge production are mutually implicated. A third novelty is the focus on ocean science. Systematic analysis of its workings and policy implications is crucial for understanding a world in which trust in scientific knowledge is no longer obvious.";1500000;1500000;ERC-2018-STG;/ERC-STG;UNIVERSITEIT LEIDEN;NL;;;;1;0;0;2;0;0 195975;660607;IE2;TERMINATED;H2020-EU.1.3.2.;MSCA-IF-2014-GF;H2020;Inclusive Education for an Inclusive Europe: Examining Social Interactions, Dynamics and Friendship Networks of Students in Mainstream Primary Schools;2015-09-01;2018-08-31;;The overarching research aim of this project is to examine the social interactions, dynamics and friendship networks of all students, with an emphasis on those identified as having special educational needs, in mainstream primary schools. The IE2 project strives to understand how inclusive education is being implemented across three countries (US, UK, Cyprus) and contribute to the debate on how to create a more inclusive European society by providing rigorous research evidence and recommendations. The project sets out to achieve three main objectives. First, to develop an innovative and interdisciplinary methodology to understand the social interactions, peer relationships and friendships with the combination of advanced social network analysis and ethnographic methods. Second, to establish a social network analysis toolkit for schools to enable practitioners understand the social dynamics within their settings. Third, to develop a platform for visualizing large datasets within social sciences and humanities. It is anticipated that the project will generate a significant impact on both the educational and social sciences and the researcher in terms of reaching a higher position of professional maturity. This is a project that is innovative and interdisciplinary as it breaks the boundaries between social sciences and humanities and computational studies, mathematics and statistics.;251857,8;251857,8;H2020-MSCA-IF-2014;/MSCA-IF-GF;UNIVERSITY OF PLYMOUTH;UK;;;;1;0;0;2;0;0 195194;655942;EnAct;TERMINATED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Enacting heritage: The aesthetic dynamics of cultural transmission;2016-03-01;2018-02-28;;"Aesthetic behaviours and expressive activities carry out a crucial role in human cultural evolution. Aesthetic cognition is important for intersubjective attunement already in early childhood, and attends to cultural emergence and transmission of ideas, practices and norms. However, anthropological scholars haven't ever investigated the cognitive dynamics whereby aesthetic behaviours shape the symbolic processes of constitution and re-enactment of cultural heritage. The proposed research project seeks to address this lacuna by dealing with key issues relating to the role of aesthetic behaviours in cultural transmission. The study focuses on how aesthetic and expressive elements are mobilized in the course of social interaction creatively transforming and communicating knowledge. The originality of the proposed approach lies in the interdisciplinary methodology that has not been used in previous studies of the subject matter. For the first time, a naturalistic and cross-cultural model of aesthetic behaviour will be applied to the context of cultural evolution. Existing naturalistic studies of aesthetics are characterized by a reductionist approach, whereas research on cultural transmission suffers due to the divide between cultural and evolutionary perspectives. This project aims to overcome the traditional opposition of “evolutionary psychology versus ethnography” through an interdisciplinary study of the multimodal, expressive, symbolic, and non-verbal practices whereby human beings collectively perform and share knowledge. The principal result of the project will be the first systematic and comparative analysis of aesthetic behaviours as operative components of cultural transmission. This result will be of interest to a broad scientific audience and will enhance several branches of European research and education, including aesthetics, cultural evolution, anthropology of art, and cultural heritage, by combining research methods derived from different disciplines.";185076;185076;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;ECOLE DES HAUTES ETUDES EN SCIENCES SOCIALES;FR;;;;1;0;0;2;0;0 215851;801474;I2-ICIQ Impulsion;SIGNED;H2020-EU.1.3.4.;MSCA-COFUND-2017;H2020;ICIQ Impulse for Talented Postdoctoral Fellows;2019-08-01;2023-09-30;;"I2: ICIQ Impulsion will impulse the professional career of 12 highly talented international fellows through the development of an innovative research programme based on interdisciplinarity, internationality and intersectoriality. This research programme will include a mandatory secondment (from two to six months) in a different research entity (academic and/or non-academic). I2: ICIQ Impulsion offers 19 research groups led by internationally renowned senior and tenure track researchers that develop excellent interdisciplinary chemical research in different areas of the chemical sciences. - Catalytic activation of chemical feedstock - Renewable energies from sunlight - CO2 capture and valorisation I2: ICIQ Impulsion fellows will have the freedom to - define an innovative research project within one of these areas of research - choose the Group Leader they would like to work with - choose a partner organisation to develop a secondment Being part of the I2: ICIQ Impulsion community will allow fellows to have: - Close supervision and mentoring by internationally renowned Group Leaders - Access to state-of-the-art scientific equipment and facilities - A personalised Career Development Plan - A tailored Training Programme - Secondments in international institutions - Networking opportunities - Dissemination and public engagement activities - Outstanding working conditions I2: ICIQ Impulsion is a very attractive programme for highly talented postdoctoral researchers looking for further opportunities in research. It has been designed to enable the maximum impact on immediate and long-term career prospects for the fellows, both in academia and in the private sector. I2: ICIQ Impulsion will also contribute to improve the attractiveness of Catalonia, Spain and Europe as a leading destination for research and innovation, boost the international visibility of ICIQ and further increase the quality of research and innovation developed in the European Research Area (ERA)";1699200;849600;H2020-MSCA-COFUND-2017;/MSCA-COFUND-FP;FUNDACIO PRIVADA INSTITUT CATALA D'INVESTIGACIO QUIMICA;ES;;;;1;0;0;2;0;0 211629;765415;FOODENGINE;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2017;H2020;Enginomics in food quality design: the case of shelf-stable fruit-, vegetable- and legume-based foods;2018-01-01;2021-12-31;;The overarching objective of FOODENGINE is to provide, for the first time, a research-based training programme to a new generation of young food scientists and technologists by introducing an enginomics approach in food quality design. It connects an omics approach to instrumentally quantify food quality with an advanced engineering approach using multi-response kinetics to model food quality changes during processing and storage. At the same time, FOODENGINE will develop models linking the enginomics-based instrumental food quality design with sensory properties, consumer acceptability and consumer preferences to create new products appealing to consumers. FOODENGINE provides unique interdisciplinary, international and intersectoral training opportunities to 13 ESRs, each for 36 months. This extensive international (5 countries), intersectoral (2 universities, 1 research institute and 6 food (ingredient) companies) and interdisciplinary (food engineering, food chemistry, food nutrition and sensory/consumer research) training should lead for all ESRs to a PhD degree. FOODENGINE will boost the career perspectives of the FOODENGINE fellows to the top level. In addition, it has the ambition to become a best-practise example for structuring PhD research training in food science and technology at the European level. Although FOODENGINE specifically focusses on sustainable commodities which are essential parts of a healthy lifestyle (fruit-, vegetable-, legume-based food ingredients and foods), the skills and new ways of thinking the fellows will acquire are generic and can be extrapolated beyond the specific application area (diverse range of food systems or food processes) in their future careers.;3437311,68;3437311,68;H2020-MSCA-ITN-2017;/MSCA-ITN-ETN;KATHOLIEKE UNIVERSITEIT LEUVEN;BE;"DOHLER GMBH;KOBENHAVNS UNIVERSITET;CARGILL R&D CENTRE EUROPE;INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE";"DE;DK;BE;FR";;1;0;0;2;0;0 195760;659246;DPaTh-To-Adapt;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Rethinking climate change vulnerability: Drivers patterns of thermal tolerance adaptation in the ocean.;2016-03-01;2018-02-28;;Climate change is having pervasive impacts on biota that is collectively resulting in a fundamental alteration of the structure, function and feedbacks within ecosystems across the globe. A major challenge for climate change science is to develop an understanding of the sensitivity of organisms to the changing environment, and try and find spatial, broad taxonomic or trait based generalities that will enable more accurate identification of regions and ecosystems at severe risk of climate change impacts (sensitivity hotspots) so that mitigation and adaptive management actions can be prioritised. There are, however, several challenges associated with predicting sensitivity hotspots. At the forefront of these challenges is our understanding of the drivers of organism’s thermal tolerance thresholds, and the proximity of temperature thresholds to the local climate extremes and climate change projections, herein called thermal safety margin (TSM). This project merges concepts from physiology, ecology, evolutionary biology, biogeography and physical oceanography into an interdisciplinary conceptual framework that exposes inconsistencies among current paradigms and fundamental limitations to our understanding of the sensitivity of marine organisms to climate change. The conceptual framework presented here offers a testable, interdisciplinary model to address this knowledge gap. Specifically we ask the questions 1) How do patterns in thermal tolerance breadth and thermal safety margins vary throughout species’ geographical ranges? And 2) What are the environmental drivers, biotic traits and evolutionary factors that determine an organisms thermal tolerance? Through identifying the nature of thermal tolerance patterns and identifying some of the mechanisms influencing these patterns, this research aims to increase the accuracy and resolution of predictions of the sensitivity of marine biota to climate change.;170121,6;170121,6;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS;ES;;;;1;0;0;2;0;0 198120;656650;ABANDONMENT;CLOSED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;People under Pressure: Settlement Abandonment and Human Responses to Environmental and Socio-Economic Stress during the Medieval and Post-Medieval Periods;2016-01-01;2017-12-31;;"The ABANDONMENT project explores the pan-European phenomenon of settlement desertion and shrinkage, which occurred especially during the 14th and 17th centuries. Despite considerable attention being paid to this particularly rich aspect of archaeological records (within several disciplines), the process of abandonment still remains poorly understood. The project aims to explore how rural communities and the settlements they lived in responded to socio-economic and environmental stress. The specific objectives are: (a) to determine the processes of settlement shrinkage and abandonment across England; (b) to contextualise changes in settlement patterns within wider transformations of land-use within distinct regions in the longue durée perspective; (c) to explore the cultural and environmental context of settlement evolution (and extinction) across northern and central Europe to determine the impact of these factors on communities. This interdisciplinary research programme will bring together well-published and especially unpublished data from excavations and fieldworks. These will be supplemented by aerial photographs, LiDAR data, documentary evidence, historical maps, field-names and palaeoenvironmental data, with their collection and analysis via a GIS. This comparative, multi-scale research covers contrasting areas in the UK that were meaningful in the past in terms of their settlement pattern, geographical conditions and economy (the moors of the South West England, East Anglia, the claylands of the East Midlands and the North East of England), and tests the outcomes in broad geographical context through a comparison with Continental Europe. The fellowship in the University of Exeter, with the largest group of landscape archaeologists focusing on the historic period in the UK, enables the applicant to receive high-quality training. New gained skills and experience of the researcher will enhance his future interdisciplinary and international career perspectives.";183454,8;183454,8;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;THE UNIVERSITY OF EXETER;UK;;;;1;0;0;2;0;0 196979;665593;RIFP;SIGNED;H2020-EU.1.3.4.;MSCA-COFUND-2014-FP;H2020;Rutherford International Fellowship Programme;2015-07-01;2020-06-30;;"The Rutherford International Fellowship Programme (RIFP) will be a new, high-quality Post-Doctoral scheme aimed at research excellence and promoting researcher mobility and training. The Programme will be open to applications across a very diverse range of science areas, spanning the world-class expertise of facilities and departments run by the UK Science and Technology Facilities Council (STFC) at the Rutherford Appleton Laboratory (RAL), the Daresbury Laboratory (DL) and the UK Astronomy Technology Centre (UKATC). Included will be the ISIS neutron and muon source, Diamond Light Source, RAL Space, RAL Particle Physics, the Central Laser Facility, Accelerator Science and Technology, Scientific Computing and STFC Technology Department. The Fellowships will be a unique opportunity for researchers to work within high quality interdisciplinary science campuses. RAL/DL/UKATC provide excellent environments for post-doctoral researchers: they have a wide variety of facilities and equipment for researcher use, experienced science staff to support Fellows' research, and are visited by many thousands of researchers every year who use the central facilities, ideal for networking and collaboration. The Programme will support 36 2-year Fellows over its 5-year term. There will be three, annual calls for proposals, widely publicised to attract the highest quality researchers. Fellowships will aim for scientific excellence, with consideration also for interdisciplinary and inter-sectoral activity. Fellows will be supervised by experienced STFC and Diamond researchers, who will be concerned not just with their scientific progress but with their wider training and development. STFC provides excellent working and employment conditions which researchers will benefit from. STFC departments will gain high-quality international researchers working within them. Because this is a new Programme it is expected to have high impact for the Fellows themselves and their host department.";5097600;2548800;H2020-MSCA-COFUND-2014;/MSCA-COFUND-FP;SCIENCE AND TECHNOLOGY FACILITIES COUNCIL;UK;;;;1;0;0;2;0;0 198287;675378;GRACE;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2015-ETN;H2020;GRACE: Gender and Cultures of Equality in Europe;2015-10-01;2019-09-30;;"The aim of the GRACE (Gender and Cultures of Equality in Europe) project is to systematically investigate the cultural production of gender equalities within Europe. Extending the success of GEMMA, the Erasmus Mundus ‘Masters of Excellence’ in Women’s and Gender Studies, the central objective of GRACE is to become the programme of reference for innovative interdisciplinary doctoral training for early career researchers. Previous scholarly work focuses on European gender equality policies. GRACE draws on innovative and interdisciplinary methodologies to investigate an under-examined aspect of those processes, namely the production of cultures of equality that underpin, enable and constrain those changing policy and legislative frameworks. Our methodological approach understands culture as neither normative frameworks nor ways of representing the world, but more fundamentally as the process through which people create the worlds they inhabit. The GRACE project will recruit, employ and provide advanced training for 15 ESRs who will research the production of cultures of gender equality across five specific sites where cultures of gender equalities are produced and contested by differently situated social agents. These five sites form the core of our research and training Work Packages, and are focused as follows: mediated cultures of gender equality (WP 1); urban cultures of gender equality (WP 2); intellectual and activist cultures of gender equality (WP 3); textual and artistic cultures of gender equality (WP 4); employing cultures of gender equality (WP 5). In sum, GRACE is designed to: equip the next generation of ESRs to play a leading role in developing advanced techniques for investigating the production of cultures of gender equality; translate creative and critical capacities into innovative cultural practices within and beyond academia; and enable them to take up positions as experts in producing new gender equalities cultures.";3719102,04;3719102,04;H2020-MSCA-ITN-2015;/MSCA-ITN-ETN;UNIVERSITY OF HULL;UK;"UNIVERSIDAD DE GRANADA;KOZEP-EUROPAI EGYETEM;UNIVERSIDAD DE OVIEDO;ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA;ASSOCIAZIONE ORLANDO;UNIWERSYTET LODZKI;UNIVERSITEIT UTRECHT";"ES;HU;IT;PL;NL";;1;0;0;2;0;0 193537;637877;PredicTOOL;SIGNED;H2020-EU.1.1.;ERC-StG-2014;H2020;Nanomethods to understand what makes an endogenous protein immunogenic;2015-04-01;2020-03-31;;"One of the major challenges in understanding the complex immune system is the question when and why this defense system attacks endogenous proteins (i.e. self-proteins). Currently, there are no reliable methods to predict what induces such an immune response, despite it has a major impact in medicine by causing autoimmune diseases, and in biotechnology by inducing adverse reactions towards new drugs. PredicTOOL will concentrate on antibody-mediated immune reactions to endogenous proteins. By high sensitivity nanotechnological tools based on spectroscopic and imaging techniques (e.g. Circular Dichroism Spectroscopy, Single Molecule Force Spectroscopy, Isothermal Titration Calorimetry, Fluorescence Microscopy), PredicTOOL will identify common patterns that characterize the interaction of autoantibodies with their antigens and further interaction with cells of the immune system. We will use well characterized human model diseases (cardiovascular). The proposed technologies will allow applying the rules of classic mechanics to identify the pattern of autoantibody-antigen interactions and will lead to better understand why an endogenous protein induces an immune response. The project aims to: i) identify patterns expressed in proteins to which autoantibodies bind on a nanometer scale; ii) investigate whether certain mutations or post-translational changes in the proteins facilitate conformational changes leading to expression of such patterns; iii) assess the binding of human autoantibodies to such modified proteins and compare this with the binding to the wild type/native protein; and iv) develop a platform of microstructured arrays to investigate immunogenic proteins. The results of this highly interdisciplinary and translational project will allow to better understand autoimmunity and to develop new ways for prevention and treatment in medicine, and to optimize the production of safer biotherapeutic drugs. The vision of PredicTOOL is that physics has the potential to substantially change the view on the pathogenesis of autoimmunity. It is highly interdisciplinary and bridges in a translational approach, immunology, physics, biotechnology and medicine. It targets to identify patterns driving antibody-mediated cardiovascular diseases. The project bears two major areas of application. In medicine, it can lead to better understand autoimmunity and to develop new ways for prevention and treatment. In the development of biotherapeutics, it can help to finally produce safer biotherapeutic drugs. The biggest strength of the project is to directly work in the human system (proteins and antibodies) applying state-of-the-art nanotechnological techniques and physical methods. We have already established the proof-of-principle of our approach using PF4/heparin model system, which now allows transferring our findings to other proteins to identify common patterns.";1491250;1491250;ERC-2014-STG;/ERC-STG;UNIVERSITAET GREIFSWALD;DE;UNIVERSITATSMEDIZIN GREIFSWALD KORPERSCHAFT DES OFFENTLICHEN RECHTS;DE;;1;0;0;2;0;0 211484;781234;Garsia;CLOSED;"H2020-EU.2.1.1.;H2020-EU.2.3.1.";SMEInst-01-2016-2017;H2020;Moving from Cure to Care: an integrated care delivery platform for a new person-oriented approach;2017-08-01;2017-11-30;;"'Health and Social systems are complex by nature and frequently disorganized. Each country, region and even each hospital or town use different software solutions which do not communicate among them. The social and health professionals are not aware of some information within their own sector and totally blind to all information among sectors. This results in: confusion, repetition, delays, duplication, gaps in service delivery, and people getting lost in the system. All these shortcomings imply a high cost for the National Health and Social Systems as well as many inconvenience to the users. The Garsia® Socio-health platform allows the management of the life pathway for patient care through a personalized interdisciplinary approach that places the individual at the heart of the system, overcoming the traditional medical approach centred on curing a single pathology. Garsia meaningfully integrates relevant information from social services and health systems into a single integrated platform useful for each stakeholder involved in the patient#39;s treatment. It offers many advantages such as an interdisciplinary management of patients (chronic and multi-pathologic), service optimization and improvement, the empowerment of the patient, interoperability through international standards while reducing inappropriate costs (8 billion euro on NHS). SofTech is a 19 year old SME created by professionals in the social and clinical sector which generated €2.3 M turnover last year. Our major asset to succeed is that we have already penetrated the public market, as we have already contracts in place with relevant players on the Italian and French Social and Health Systems. We have estimated that after 5 years from launch, we will have engaged at least 150.000 patients, and will have hired 60 new employees (sales, technical, etc.) in different EU countries. We will earn almost €14.2M cumulative profit and generate a R.O.I of 7.83 by commercializing Garsia.'";71429;50000;H2020-SMEINST-1-2016-2017;/SME-1;SOFTECH SRL;IT;;;;1;0;0;2;0;0 195337;656830;DRC-ECSA;CLOSED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Hierarchical surface patterns from dissolution-reaction-crystallisation mediated evaporation controlled self-assembly (DRC-ECA) and its antimicrobial coating application;2015-09-04;2017-09-03;;"A preliminary study by the applicant (Dr. Hua Wu (HW)) has proposed a novel dissolution-reaction-crystallisation mediated evaporation controlled self-assembly (DRC-ECSA) mechanism, from surprising and unprecedented observations of complex residual surface patterns with hierarchical architecture self-assembled upon evaporative drying of a ZnO nanofluid droplet. This mechanism is very di?erent from that previously established for the co?ee ring e?ect and other ECSA processes, and the morphological and nanostructural details of the obtained surface patterns also depend intricately on – thus are tuneable by – a range of physical parameters. Much of the complexity due to these corroborating factors remains to be fully explored. The aim of the project is threefold: 1) to fully understand the DRC-ECSA mechanism by comprehensively investigating the effects of physical parameters such as the solvent mixtures, evaporation rate, ZnO nanofluid concentration, shape and size of ZnO particles, addition of surfactants and polymers, substrate chemistry, droplet volume, temperature and humidity; 2) to apply and extend the DRC-ECSA mechanism (e.g. in a confined geometry and using binary particle mixtures) to obtain sophisticated surface patterns with tailored morphologies and hierarchical structures; 3) to evaluate the efficacy of the surface patterns for potential applications in antimicrobial coatings. By leading and engaging in the proposed project, Dr. HW will acquire new skills and knowledge in a range of interdisciplinary and multidisciplinary scientific and technical areas, including non-equilibrium ECSA, nucleation and crystal growth, morphological and structural characterization, nanoparticle synthesis, and microbiology of nanostructured surfaces. A broad range of transferrable skills acquired through the enriching experience of this interdisciplinary project will be very beneficial to Dr. HW’s longer term career plans to become an independent research leader.";195454,8;195454,8;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;UNIVERSITY OF BRISTOL;UK;;;;1;0;0;2;0;0 205910;707827;OXFORDCHOIRS;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;CULTURAL POLICY AND CHORAL-HISTORICAL IDENTITY IN THE CHORAL/MUSICAL LIFEOF OXFORD UNIVERSITY COLLEGES AND HALLS IN THE 21ST CENTURY;2016-09-01;2017-08-31;;"This project presents an interdisciplinary study on the collective identities and (sometimes contested) cultures of collegiate choirs at University of Oxford (UOXF) and focuses on cultural-political issues and challenges facing the choral/musical tradition in UOXF colleges and halls in the 21st century. This project refers to extra-curricular music activities in the academic context, which relate to the current European Agenda for culture (accessible and inclusive culture and cultural heritage as well as referring to current societal challenges in Europe (social inclusion) whereas the project deals with musical activities in a somewhat elitist community. Drawing predominantly on the Sociology and Psychology of Music, as well as the contemporary history of Music and Cultural Policy, this interdisciplinary study can be divided into two main strands of research: A) Firstly from the perspective of students; to map the demographical background and social structures of members of the collegiate choirs and how the historical tradition affects and shapes the collective identities and individual cultures of the choirs. B) Secondly from the perspectives of staff/administrators; to study the cultural-political issues in ‘governmental’ decision making regarding the future of the collegiate choirs in terms of perspectives like politics of admission, competition for musical talent, forms of musical direction, gender perspectives, financial distribution and inequalities, musical hierarchies and the possible impact of cuts in public funding to musical school activities in general.";97727,4;97727,4;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;UK;;;;1;0;0;2;0;0 198323;676201;CHESS;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2015-ETN;H2020;Connected Health Early Stage Researcher Support System;2015-09-01;2019-08-31;;"Changing demographics and increasing pressure on health related resources mean that new models of care must be found. Fortunately, technology developments and increasing digital literacy mean that we can now put the correct information in the correct hands at the correct time. This is connected health and it allows patients, clinicians, and planners to make better decisions. Ultimately, these decisions can save lives, save money and ensure a better quality of life for the patient during and after treatment. Connected Health is an emerging market and an emerging science. It requires “t-shaped” individuals with deep disciplinary expertise allied to a broad understanding of a variety of domains including business, economics, life science, health science, computer science, social science and engineering. Current research and training programmes in Europe do not address this need and adoption of Connected Health solutions and practices is limited as a result. CHESS will develop connected health scientists and champions who have a broad understanding of multiple domains, who can communicate in an interdisciplinary world and who can operate across the education, industry, health and policy sectors. CHESS will include intersectoral secondments, interdisciplinary communication skills, public engagement and outreach with particular focus on patient, clinician and policy-maker audiences. This will build on the programme of interrelated core research projects which will address gaps in the knowledge and evidence base for Connected Health in terms of health economics, use of big data, personal sensing, business modelling, navigating markets and ecosystems, change management and user-led design.";3950971,2;3950971,2;H2020-MSCA-ITN-2015;/MSCA-ITN-ETN;UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN;IE;"OULUN YLIOPISTO;ARISTOTELIO PANEPISTIMIO THESSALONIKIS;BEACON HOSPITAL SANDYFORD LIMITED;Chambre de Commerce et d'Industrie de Grenoble;PHILIPS ELECTRONICS NEDERLAND B.V.;SALUMEDIA TECNOLOGIAS SL;UNIVERSITY OF ULSTER";"FI;EL;IE;FR;NL;ES;UK";;1;0;0;2;0;0 195997;660769;SMILE;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;3D Silicon Micromachining with Infrared ultrafast LasErs;2015-09-30;2017-09-29;;"The aim of the present proposal is to initiate an interdisciplinary research program to develop 3D micromachining of silicon towards novel silicon photonics and microfluidic applications. We are motivated by the myriad of applications based on 3D micromachining of glass that peaked in the early 2000's, and still continues to impact integrated photonics and microfluidics, among other fields. These successes were achieved using lasers at wavelengths for which glass is transparent (most commonly 1 um, 800 nm and their second harmonics). Most of the important results demonstrated in glass can be carried over to silicon using a long-wavelength laser (beyond 1.1 um, silicon is highly transparent), though it is clear that the physics will be different, not least because glass is amorphous and silicon is crystalline. To this end, we propose an interdisciplinary research effort that includes first developing the necessary laser technology, then building up the physical understanding, and finally pursuing high impact applications. Our approach can be summarized as: (1) Developing a novel, femtosecond, high-energy laser at 1.5 um, (2) Developing in-situ diagnostics based on pump-probe imaging of the laser-material interaction, (3) Exploring the physics of the laser-silicon interaction, (4) Applying our physical understanding and laser technology as a platform to 3D micromachining of silicon towards novel silicon-photonics and microfluidic applications.";145845,6;145845,6;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;BILKENT UNIVERSITESI VAKIF;TR;;;;1;0;0;2;0;0 194873;653508;Phil-Threats;CLOSED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;The Representation of External Threats in the Configuration of Spanish Power in the Philippines (1600-1800);2016-02-01;2018-01-31;;"Challenging the traditional understanding of colonial rule in the early modern period, this project proposes a new perspective on how colonial systems of dominance operated, offering an innovative view on mechanisms of governance. Applying interdisciplinary methods, it emphasizes political communication as key element in the creation and consolidation of a system of power. Focussing on the colonial Philippines as a transcontinental cultural contact zone, this project investigates the concept of external threats as a fundamental element of political communication. Thereby, it advances simultaneously along two analytic lines, investigating (1) forms of threat representation, and (2) their effects. Based on the sociological theory that external threats can foster the cohesion of a group, the hypothesis of this project is that specific representations of “enemies” contributed to the success of the Spanish colonial system for a long period (1565-1898), by strengthening the unity within the Spanish system and helping to overcome internal problems. To prove this effect, the project combines aspects of (1) system theory (N. Luhmann) and (2) the method of dispositif analysis (M. Foucault), which until now have only been applied separately. Based on system theory models, a concept of threat-communication is defined as a first analytic step for the investigation. It is completed with the concept of a dispositif of threat, which includes not only discourses in texts, but also visual forms of representation, objects, and performative acts – giving the project a pronounced interdisciplinary feature. Overall, the project will contribute to a better understanding of the power structures of the Spanish colonial systems in particular and mechanisms of political communication in general. In addition, it will enhance the skills of the Experienced Researcher (ER), enabling him to become a leading expert in his field and to find an independent position in research.";170121,6;170121,6;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS;ES;;;;1;0;0;2;0;0 196371;665958;MWK-Fellows;SIGNED;H2020-EU.1.3.4.;MSCA-COFUND-2014-FP;H2020;Fellowships in Advanced Cultural and Social Studies at the Max-Weber-Kolleg;2015-09-01;2020-08-31;;"The MWK-Fellows programme financed by COFUND aims to allow excellent incoming researchers from countries other than Germany (in accordance with the EU-mobility-rule) to conduct their own, freely chosen, independent research projects in a highly competitive and intellectually vibrant research environment provided by the Max Weber Center for Advanced Cultural and Social Studies (Max-Weber-Kolleg). The Max-Weber-Kolleg is a high-ranking research centre which forms an avant-garde institution of the University of Erfurt. It is distinguished by a unique organisational structure – combining the features of an Institute for Advanced Study and a Graduate School – and a ‘Weberian’ research programme. The ‘Weberian’ research programme combines historical, comparative and interdisciplinary perspectives with an interest in normative issues in the social sciences. It has a focus on societal challenges of contemporary societies, especially (religious) plurality, cultural diversity and social order, processes of acceleration and growth. The core disciplines are sociology, economics, religious studies, law, philosophy and history, but MWK-Fellows programm is open for related areas as well. The Max-Weber-Kolleg is based on the principles of interdisciplinarity and internationality with a long-standing and progressively fine-tuned fellowship programme. By means of the COFUND-action Max-Weber-Kolleg will not only increase the number of international fellows but include a new intersectoral dimension into its fellowship programme. At the Max-Weber-Kolleg, MWK-Fellows will enjoy the best possible support and an opportunity of being connected with larger research projects. Nevertheless the applicants’ freedom of choice of the research project is fully guaranteed. The MWK-Fellows programme will improve international high-level research and science with and for society and will contribute to the fostering of the European Research Area (ERA), especially in the field of societal challenges.";2832000;1416000;H2020-MSCA-COFUND-2014;/MSCA-COFUND-FP;UNIVERSITAT ERFURT;DE;;;;1;0;0;2;0;0 196373;665992;MSCA FIRE;SIGNED;H2020-EU.1.3.4.;MSCA-COFUND-2014-DP;H2020;MSCA FIRE: Fellows with Industrial Research Enhancement;2015-09-28;2020-09-27;;"MSCA FIRE: Fellows with Industrial Research Enhancement The FIRE programme is an integrated 4 year Doctoral Training programme, bringing together two national Centres for Doctoral Training: the Centre for Sustainable Chemical Technologies and the Centre for Digital Entertainment. The objectives of MSCA FIRE are to increase the international aspects of these successful intersectoral and inter-disciplinary programmes and to develop the elements of transnational mobility and career development, common to our industry facing doctoral programmes. Objectives are to: - Offer FIRE Fellows the benefits of two established national Doctoral Training Centres, as they expand their international company placement activities. - Bring Fellows the benefits of the cross-sectoral reach of both Centre, with vibrant industries. - Enhance interdisciplinarity and offer added-value training practices beyond their specialised research area, to all fellows. - Use these synergies to fire-up the fellows to become autonomous, creative, highly-skilled and fully ready for careers in international industries. This will be achieved by: - Implementing a combined 4 year doctoral training programme, - using two existing national Doctoral Training Centres and their already engaged industrial partners. MSCA FIRE will deliver: - 20 autonomous, creative, highly-skilled scientists and engineers fully ready for careers in international industries, and - A model for intersectoral, interdisciplinary doctoral training in an international environment. Industrial partners ensure that research carried out is relevant and will enhance employability of graduates, both in Europe and globally.";4185600;2092800;H2020-MSCA-COFUND-2014;/MSCA-COFUND-DP;UNIVERSITY OF BATH;UK;;;;1;0;0;2;0;0 196990;665790;SMART LOIRE VALLEY;SIGNED;H2020-EU.1.3.4.;MSCA-COFUND-2014-FP;H2020;SMART LOIRE VALLEY: Curiosity, Imagination and Intuition;2015-11-01;2020-10-31;;"The region Centre-Val de Loire, located 130 km south of Paris, has a population of 2,5 million in an area of 40000 km?. LE STUDIUM® Loire Valley Institute for Advanced Studies has its headquarters in Orleans, the capital. LE STUDIUM®’s mission is to build the human capital for research, development and innovation in region Centre, by attracting senior foreign researchers. The SMART LOIRE VALLEY (SLV) fellowship programme is designed to enhance this regional mission and support the regional implementation of the EU smart specialization concept. Over time it has demonstrated the benefits of outward looking research communities who adhere to the research values of LE STUDIUM®: Curiosity, Imagination and Intuition. For the past 10 years LE STUDIUM programmes have financed an average of 8 one-year fellowships per year and call for applications. This ambitious SLV programme – with the COFUND contribution – will fund a minimum of 12 researchers per call (4 calls for applications) over 5 years. This total of 48 worked years of research ensures region Centre will build its human capital in inter-sectorial and interdisciplinary research domains in order to drive regional and EU socio-economic outcomes from research investment and will foster the formation of new RTD poles of European scale in region Centre, enabling increased attractiveness and competitiveness. The SLV programme seeks to create synergies between disciplines and links with the industrial world in order to increase diversity and stimulate socio-economic development. Finally, it aims to develop outward looking interdisciplinary teams with a reputation in developing the EU economic landscape. LE STUDIUM® expertise resides in its capacity to manage and grow a global research network, able to create a new scientific value chain, leading to the emergence of innovative collaborative research and enterprise activity. This expertise will ensure the SLV programme achieves its goal.";3398400;1699200;H2020-MSCA-COFUND-2014;/MSCA-COFUND-FP;LE STUDIUM, AGENCE REGIONALE DE RECHERCHE ET D'ACCEUIL INTERNATIONAL DE CHERCHEURS ASSOCIES;FR;;;;1;0;0;2;0;0 204345;722562;FAWORIT 2016-2017;SIGNED;H2020-EU.1.3.5.;MSCA-NIGHT-2016;H2020;Fascinating World of Researchers in the Age of Technology 2016/2017 - The New Generation of Innovators;2016-04-01;2017-11-30;;"The main objective of our FAWORIT proposal is twofold: 1) to show the public how researchers with their innovative solutions affect our daily lives; 2) to encourage the youth – with a special focus on girls – to embark on scientific careers by involving young innovators in our programmes. Our main target group is students between the age of 8-20, but we aim to address all age groups with attractive programmes. Some novelties of our project: offering challenge-oriented activities – each of our 18 venues will present their innovative solutions related to interdisciplinary societal challenges; focussing on the concept of Responsible Research and Innovation - the audience will be informed about key elements of RRI, thus creating better understanding and fostering future involvement; launching “Science in the City” – a flash mob like activity, involving the public in spectacular experiments. We will apply an integrated approach in our project in which interdisciplinary challenges, innovative solutions, (young) researchers, their work and hobbies will be presented in an interactive, educating and entertaining way. The target audience can thus discover that being a researcher is cool and creative; researchers, but and young innovators are amongst us. Our objective is to have around 30000 visitors at the events, but a multiple of that number (around 500000) will see, hear or read about the Night. We intend to raise awareness of the European engagement in R&I; in the European Corners and at each venue related programmes of the European Union (FP7, H2020, especially MSCA) will be visible. The structure of the consortium: an innovative SME, a state-owned applied research institution, a highly innovative large company, a scientific association with a broad network of local member institutions all over Hungary and an independent think tank established by economists and sociologists together with numerous contributing partners of all kinds will ensure the success of the project.";207675;207675;H2020-MSCA-NIGHT-2016;/CSA;REGIONALIS INFORMACIOS ES FEJLESZTO TUDASKOZPONT KORLATOLT FELELOSSEGU TARSASAG;HU;"TUDOMANYOS ISMERETTERJESZTO TARSULAT;BAY ZOLTAN ALKALMAZOTT KUTATASI KOZHASZNU NONPROFIT KFT.;HETFA KUTATOINTEZET";HU;;1;0;0;2;0;0 195315;656741;ALGOVIS;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Algorithmic Approaches to Spatially-Informed Information Visualization;2015-09-01;2016-10-31;;"We propose a fellowship that will propel an outstanding young researcher and provide him with the skills, experiences and contacts that will enable him to develop into a key contributor to international and interdisciplinary research in an important emerging field that has wide application in commerce, government and industry. Computational Geometry is largely theoretical whilst Information Visualization is broadly applied. The proposal focuses on a talented computational geometer, who has already begun working with colleagues and commercial organizations across the world to develop his research in an applied context with some success. It embeds him in a renowned Information Visualization group at CITY University London—an institution that is uniquely positioned both academically and geographically, with its portfolio of professional education and proximity to one of the world’s leading centres of technology-fuelled creative industry. The fellowship will provide access to academic expertise in a complimentary discipline, experience and training in research and entrepreneurship, and close collaboration with partners in industry and government. This interdisciplinary research and training will equip an experienced researcher with the skills, experience and contacts to move an important applied discipline forward in the future. With a programme that draws upon formal provisions within CITY and takes advantage of existing contacts with partners in London from the commercial sector, the fellowship will: (1) add algorithmic rigour to Information Visualization design; (2) inform algorithmic design through access to other disciplines and practitioners; (3) provide the researcher with experience of new fields and practices; (4) bring two complimentary fields together and change disciplinary mindsets; (5) develop the researcher through experience and training in research, teaching and entrepreneurship and by developing his international network across disciplines and sectors.";107015,3;107015,3;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;CITY UNIVERSITY OF LONDON;UK;;;;1;0;0;2;0;0 201035;702466;EVIDENCITY;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Documenting Sarajevo: City and Society During and After the War;2016-09-01;2018-08-31;;"The aim of this architectural research is to analyses material transformations of Sarajevo—the destruction and reconstruction caused by the war (1992-1996), from documents (videos, photos, and drawings) produced by citizens. Finding these documents is important in the shared process of collective memory creation by Bosnians, but also for academic research and post-war reconstructions. For EU citizens, understanding Sarajevo citizens’ experience can help them to understand the realities of life of the actual war contexts (i.e. Syria). As a citizen who experienced the war, an architect and a researcher of the war cities, my research objective is to expand architectural research methods by focusing on how war affects the transformation of cities through a process combining architecture and media research. I will apply interdisciplinary research methods used in architecture/planning (i.e. geographic information system - GIS), media studies (i.e. video) and anthropology (i.e. interviews). To use media tools is a complement to architect research and representation (i.e. video) modes because they create documents (i.e. drawings) understandable only to architects. Research will be accessible to scientific and general public through a web platform, called Evidencity, which will include map-based, multimedia research archive. Regarding to my academic career this project contributes: obtaining academic profile in the fields of architectural research methods and media for researching of different war cities; advancing my skills as an architect (i.e. analysis of the destroyed city) for working on projects related to the post-war reconstruction. The European continent is constantly dealing with states of war, on its territories (Ukraine) or on its borders (Libya-Italy). Proposal aims to contribute using research results to create interdisciplinary guidelines for architectural research to the emerging field of urban conflict studies that will be applicable to the other war cities.";177598,8;177598,8;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;TECHNISCHE UNIVERSITEIT DELFT;NL;;;;1;0;0;2;0;0 215805;800364;PAERADOX;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Precursors to Modern Aerobic Ammonium Oxidation: Oxygenic and Electrogenic Anaerobic Pathways;2018-08-01;2021-07-31;;How did microbes evolve to use O2? How did O2-dependent pathways derive from or evolve under anoxic conditions? This central evolutionary mystery remains essentially unresolved. I contend that it is possible to identify the evolutionary history of modern aerobic pathways (APs), by discovering the vestiges of ancient anaerobic pathways (AnPs) that persist in modern microbes. Aerobic nitrifiers contain aerobic metabolisms, while few clues such as chlorite dismutase enzyme in Nitrospira, NO dismutase enzyme in Methylomirabilis, and electrochemical signals from aerobic nitrifiers support the notion that remnants of AnPs remain. Hence, I postulate that in nitrifiers currently considered strict aerobes, I can identify the vestiges and integral remains of the earliest APs: I will identify the AnPs of NH4\ oxidation that are driven by intracellular O2 production and respiration mediated by EET. By applying BES and batch incubations followed by isotopic and genomic experiments will evidence and characterize the novel AnPs in nitrifiers. Single cell genomics on FAC-sorted fluorescent-tagged cells followed by molecular phylogenetic analysis will provide a major contribution to unravelling the early evolution of aerobiosis and aerobic NH4\ oxidation, which is crucial as we seek the origins of life on Earth, and other planets. PAERADOX will provide me an interdisciplinary research training in the area of microbial physiology and genomics, molecular biology and computational evolution through international mobility (Harvard, MIT and DTU). Such a training-through-research platform will enhance my career development to a large extent. My return and reintegration to DTU will provide basis to transfer my interdisciplinary combination to European scientific community. I am confident that the international network, skills and knowledge that will be constructed during PAERADOX is an excellent investment for my future and for EU’s strength in the field of microbial evolution and ecology.;278227,8;278227,8;H2020-MSCA-IF-2017;/MSCA-IF-GF;DANMARKS TEKNISKE UNIVERSITET;DK;;;;1;0;0;2;0;0 209244;747313;URBANiTE;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Post-crisis urban governance transformations in Southern Europe: a comparativist approach;2017-10-02;2019-10-01;;The post-crisis transformations of the socio-political landscapes in Southern Europe have shaped crucial opportunities for emergent political actors and the civil society to introduce new governance mechanisms. Following a turbulent period of social mobilizations, rapid political and institutional transformations are underway at the city, regional and national levels in countries such as Spain and Greece, and particularly in Madrid and Athens. These provide a crucial theoretical, methodological and analytical challenge for urban studies and a key opportunity for the development of a novel relational comparative approach regarding the modifications of urban governance in Madrid and Athens. The prime research aim of URBANiTE is to investigate the ongoing socio-political developments in the two cities, the relationship between civil society and emergent political actors and the ways these shape institutional changes. The project will produce context-sensitive, innovative outcomes on multi-level territorial governance, of high relevance for science, society and policy, in times of sweeping challenges in Europe and beyond. Moreover, it involves integrated interdisciplinary research with policy implications for the governance of inclusive, innovative and reflective societies, hence fully responds to challenges set out in the Horizon 2020 Societal challenges programme. The Fellowship will provide opportunity for knowledge exchange, as the fellow will bring expertise from the UK and Greece on urban politics, citizenship and grassroots social innovation in austerity contexts. It will also allow the fellow to advance her knowledge in an interdisciplinary research environment and learn from a new regional context, which will contribute to greater understandings of urban governance changes, social innovation and policy implementation in contemporary Europe. Lessons generated will be of wider relevance for EU- level urban governance, with transferable outcomes to other contexts.;158121,6;158121,6;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;UNIVERSIDAD AUTONOMA DE MADRID;ES;;;;1;0;0;2;0;0 208679;750092;NpQFT-NEq;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;New non perturbative methods for out-of-equilibrium quantum field theory;2017-05-01;2019-04-30;;"A full understanding of the out-of-equilibrium dynamics of many-body quantum systems is one of the ultimate goals of statistical physics. It is often extremely difficult to compute how physical quantities evolve with time in these settings, and to know when and how these systems eventually can reach some form of equilibrium. This difficulty is specially marked in systems described by quantum field theory, where non equilibrium dynamics are still less well understood than in discrete lattice models and quantum spin chains. Recent years have seen many developments of powerful non perturbative methods for understanding equilibrium quantum field theory, from different areas of physics. There seems, however, to be a disconnection between the plethora of new techniques developed in areas like high energy physics, nuclear physics, and cosmology, and the few applications these have seen in some of the younger active disciplines in non equilibrium quantum field theory, such as understanding the time evolution of observables and equilibration dynamics in low dimensional and strongly correlated systems. The main aim of this proposal is to implement an interdisciplinary approach to understand out-of-equilibrium physics, and quantum field theory in particular, borrowing and developing techniques from areas of high energy physics, such as non Abelian gauge theories, supersymmetric field theories and resurgent transseries, and from condensed matter physics, such as Bethe ansatz solutions and new quasilocal conserved quantities for integrable lattice models. This will provide several new analytical methods to approach non equilibrium field theory that go beyond perturbation theory and methods based on integrability. The success of this action will be ensured by the interdisciplinary backgrounds and expertise of both, the applicant and the host, as well as the diversity and opportunity for collaborations found at the host institution.";177598,8;177598,8;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;UNIVERSITEIT UTRECHT;NL;;;;1;0;0;2;0;0 209211;745948;SYMBIOTIC BODY;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Unlocking the virtual body: Exploiting the symbiotic relationship between an avatar and its user to modify bodily experience and improve the outcome of eating disorder treatment;2018-01-12;2020-10-30;;Successfully fighting eating disorders (EDs), whose prevalence is rising and expected to be one of the highest-ranking causes of mental illness in the Western world by 2020 with ever-increasing costs of institutional healthcare in and beyond Europe, interdisciplinary efforts to elucidate their underlying, enigmatic, mechanism of body image disturbance, BID (the experience of one’s body as fatter/larger than it actually is) and improving the effectiveness of existing evidence-based interventions are now imperative, also according to the European Council of EDs and the National Institute of Mental Health (USA). Substantial advances in this area crucially depend on improved understanding of disease mechanisms while extant treatment strategies are hindered by the lack of specified conceptual models underlying the mechanism driving the extremes of BID in EDs, causing huge costs to individuals and society at large. However, as reported in the top-tier journals, the applicant and co-workers’ “allocentric lock” model of EDs provides a rich conceptual framework for elucidating the source of BID and factors causing ED patients to be “locked” in a “virtual body” (e.g. my body is fat) that they detest and differs from the real one. This interdisciplinary project (with integrated training), going beyond the state-of-the-art not only aims at a) providing further evidence for the existence of allocentric lock in EDs and b) assessing its neural bases, but also c) setting and tuning a virtual reality-based embodiment device able to unblock the “virtual body” by exploiting the symbiotic relationship between an avatar and its user, and testing it in integrated first-line ED treatment approaches (randomized controlled clinical trial). The Symbiotic Body project work, also having the potential to open a path to a new vision of e-health (strategic H-2020 area) -e-mbodied health, will be disseminated and notified to the international scientific/clinical community and the general public.;158121,6;158121,6;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;UNIVERSITAT DE BARCELONA;ES;;;;1;0;0;2;0;0 208930;747665;BH-STRING-HOLO;TERMINATED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Black Holes in String Theory and Holography;2017-10-01;2019-09-30;;"Black holes are among the most fascinating and enigmatic objects in our universe. The internal structure of black holes is of significant interest for quantum gravity, for astrophysical phenomena, and for the study of quantum entanglement in systems with many degrees of freedom. The Black Hole Information Paradox, which sharply demonstrates the incompatibility of Quantum Mechanics and General Relativity, is a primary motivation for this proposal. The proposed research will also yield insight into fundamental aspects of quantum gravity such as singularity resolution and the emergence of spacetime. The research described in this proposal studies black hole microstates in String Theory, supergravity and holography. The ultimate goal of this line of research is a complete characterization of the internal structure of black holes. The objectives of this proposal are: 1) To establish the microscopic description of several classes of black hole microstate supergravity solutions, through holographic studies; 2) To construct and study supergravity solutions describing microstates of non-extremal black holes, in particular solving for solutions that display new topological structures; 3) To investigate the observability of black hole horizon-scale structure at experiments such as LIGO, through interdisciplinary work to build models of string-theoretic black hole internal structure and predictions for experiment that can be tested in the near future and beyond. These objectives will be achieved by combining the applicant’s knowledge and recent results on black hole microstate solutions with the expertise of different members of the host research group in the areas of holography, supergravity solutions and gravitational wave experiments. Through this research, the applicant will develop new technical, interdisciplinary, research leadership and management skills, significantly enhancing his career potential.";195454,8;195454,8;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;UNIVERSITY OF SOUTHAMPTON;UK;;;;1;0;0;2;0;0 208705;751684;HIVOL;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Herbivore-induced emissions of biogenic volatiles from arctic plants under climate warming;2018-04-01;2020-03-31;;Biogenic volatile organic compounds (BVOCs) play important roles in biosphere-atmosphere interactions. However, it remains unexplored how climate warming and concomitant increase in insect herbivory interact to influence emissions of BVOCs from arctic plants. This greatly limits the current understanding of the complex abiotic and biotic processes controlling BVOC emissions in arctic ecosystems, and hampers the development of appropriate BVOC emission models. Here, I propose a project that will assess 1) how climate warming influences insect herbivory on dominant woody plants in the Arctic, 2) how insect herbivory, both alone and in conjunction with warming, influences plant BVOC emissions, and 3) how to integrate herbivory effects into the existing emission model to estimate these effects at the landscape scale. The project takes an interdisciplinary approach involving insect science, environmental science, chemical ecology and ecosystem modeling, and it combines my research experience on biotic control of BVOC emissions and the expertise that the host has on the bidirectional exchange of BVOCs between the ecosystems and the atmosphere in the Arctic. This forms a strong basis for making the project a success. The importance of biotic control of BVOC emissions in the Arctic is unknown and this project will generate pioneer results that are awaited in the scientific community. The outputs of this project will lead to important scientific breakthroughs and improve our comprehension of the factors driving BVOC emissions as well as the ecological and atmospheric functioning of BVOCs in the rapidly changing Arctic. The project will also lead to novel collaborations due to the strong complementarity between my own research and the research of the host and collaborators. The expected high-quality publications, practice training and interdisciplinary collaborations will be valuable assets that support my career development towards full independence.;212194,8;212194,8;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;KOBENHAVNS UNIVERSITET;DK;;;;1;0;0;2;0;0 209752;740264;GenomMed;SIGNED;H2020-EU.1.3.4.;MSCA-COFUND-2016;H2020;Genomics and Mechanisms in Translational Medicine Doctoral Programme;2017-04-01;2022-03-31;;"The GenomMed programme will train international experts who are wanted in the European job market and future research leaders in translational genomics. These experts aim to solve health care -related questions in cardiovascular and metabolic diseases and neurosciences. They will have skills to create solutions and innovations to develop novel treatments in the European and global environment. Health care is globally faced with a growing burden of major age-associated diseases. New means of diagnosis and treatment are needed to survive the challenges. This will be gained by offering world class research-oriented PhD training in genomics, cardiovascular and metabolic diseases, neurosciences, and clinical adaptation of research results. In depth knowledge and methodology training will be topped up with well-planned transferable skills curricula providing the graduates with skills needed in changing career paths after their initial researcher training. Other means to achieve training goals include well-planned mobility periods to international collaborators’ research environments, meaningful secondments at intersectoral partners’ projects, and frequent exposure to interdisciplinary activities between the participating research groups. The GenomMed Doctoral Programme will take the researcher training to the next level in terms of research excellence, productive international and intersectoral mobility, and interdisciplinary exposure. Graduates will gain a unique set of research and transferable skills. Career development is a built-in feature of the training leading to increased employability of graduates in and outside academia and enhanced R&I input for the European economy and society. In pursuance of better trained PhDs, HR practices of hosting institutions will be developed and harmonized, and intersectoral collaboration will become regular. Furthermore mobility schemes at system level will develop and become part of everyday actions in research organizations.";2511360;1255680;H2020-MSCA-COFUND-2016;/MSCA-COFUND-DP;ITA-SUOMEN YLIOPISTO;FI;;;;1;0;0;2;0;0 208580;746186;POSEIDoN;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Atlantidae: Predators at the Ocean SurfacE as InDicators of chaNge.;2017-07-03;2019-07-02;;"Large-scale ocean changes, including ocean acidification (OA) and ocean warming (OW), are projected to occur over the next 50-100 years as a result of elevated atmospheric CO2. Living close to the atmosphere/ocean boundary, plankton are particularly vulnerable to, but also excellent indicators of these changes. Euthecosome pteropods (small swimming gastropods) have been highlighted as bio-indicators because their delicate aragonite shells are susceptible to OA. However complex feeding behaviours have impeded laboratory experiments on pteropods, limiting research to short term studies. The proposed action will apply an interdisciplinary approach to investigate the past, present and future effects of OA and OW upon the planktonic family Atlantidae, and to evaluate their use as bio-indicators. Atlantid heteropods are also small (max. 14 mm), aragonite shelled, planktonic gastropods that are sensitive to OA and OW. Unlike pteropods, atlantids are predatory and have the potential to be excellent experimental organisms with which to investigate the effects of these surface ocean changes. Atlantids also provide a unique opportunity to investigate the effect of OA and OW at an as-yet unstudied and potentially more sensitive trophic level. The Experienced Researcher has worked with atlantids for >8 years and is one of very few researchers able to identify atlantid species. As such, she is uniquely positioned to deliver the objectives of this interdisciplinary project. The proposed research will provide opportunities for the Researcher to advance her career and skill-set through specialist training and teaching opportunities. The proposed action will improve our appreciation of how surface ocean changes will affect zooplankton and produce high impact data that are relevant to a wide body of marine scientists. The atlantids are also beautiful, charismatic gastropods, and excellent ambassadors for engaging the public and policy makers with current ocean changes.";177598,8;177598,8;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;STICHTING NATURALIS BIODIVERSITY CENTER;NL;;;;1;0;0;2;0;0 210344;754315;DSSC;SIGNED;H2020-EU.1.3.4.;MSCA-COFUND-2016;H2020;Data Science and Systems Complexity Research Training Programme;2017-05-01;2022-04-30;;"Today’s world is a highly complex system that is producing massive amounts of data daily. We can only progress towards urgent global priorities such as sustainable energy, personalized healthcare or the development of the data-driven economy if we can predict the dynamic nature of such a system. This challenge calls for an integrated approach that uses data to understand the behaviour of complex systems, and for experts who can handle data and complexity problems for society at large. The DSSC Centre at the University of Groningen responds to this demand with a doctoral programme that offers Big Data and Systems Complexity training to ten early stage researchers. To combat the current fragmentation of data and complexity research along disciplinary lines, the DSSC Programme has an interdisciplinary format based on the premise that complex systems generate big data, and big data help identify, control and analyse complex systems. The DSSC mission is to enable students to become experts who provide effective data & complexity solutions for European strategic fields: energy, healthcare, safety and cybersecurity, smart industry, space and advanced instrumentation. As an interdisciplinary training programme it will prepare students to master modelling, computational and analysis methodologies from mathematics, statistics, computer science, engineering, and to manage Big Data in disciplines such as astronomy, physics, bioinformatics. It will develop the students’ intersectoral and international mobility through entrepreneurial training, internships and collaborative projects with major local and European stakeholders. The DSSC provides an optimum training environment: access to first-rate research facilities and experienced supervisors in a top 100 university where more than 50% of the PhD population comes from abroad. In the future, the Programme endeavours to foster an international collaborative research network that will address data and complexity challenges.";2092800;1046400;H2020-MSCA-COFUND-2016;/MSCA-COFUND-DP;RIJKSUNIVERSITEIT GRONINGEN;NL;;;;1;0;0;2;0;0 210348;754490;MINDED;SIGNED;H2020-EU.1.3.4.;MSCA-COFUND-2016;H2020;MultIscale precision therapies for NeuroDEvelopmental Disorders;2018-01-01;2022-12-31;;"Neurodevelopmental disorders (NDD) represent an enormous burden for patients, their families, and society. Within EU, the incidence of autism spectrum disorders (ASD) is increasing to over 100 per 10,000 individuals. By comparison, new cases of brain cancers in EU are estimated to be 10 per 10,000. Also, the requirement for lifelong care has a dramatic impact on healthcare costs, with an average lifelong cost per ASD patient of ~ 3.0 MEuro. The societal and economic impact, the growing incidence, and the lack of any cure call for radical changes in the way NDD are approached. At this aim, MINDED will integrate across three major technologies: nanomedicine, for the precise delivery of therapeutic and imaging agents; molecular neuroscience, for the identification of RNAs modulating key gene expression; cognitive neuroscience robotics, for the development of novel sensorimotor interventional approaches. The integration of these technologies requires the establishment of a new class of scientists and entrepreneurs trained to stretch their knowledge over multiple disciplines and think outside conventional silos. MINDED bridges together different vertical silos building common foundations for future interdisciplinary careers. The objective of MINDED is two-fold: develop a highly interdisciplinary post-doctoral training program by integrating nanomedicine, neuroscience and robotics; involve fellows in activities aimed at developing multiscale technologies for NDD. This will be achieved via two training paths: a scientist path, engaging fellows in the development of novel diagnosis and treatment approaches for NDD; a business developer path, engaging fellows on the integration of biomedical technologies in the clinic. MINDED fellows will constitute a new class of scientists and entrepreneurs capable of developing novel treatment and diagnosis approaches for complex genetic diseases and shaping the future integration of nanomedicine and robotics with neurosciences.";6796800;3398400;H2020-MSCA-COFUND-2016;/MSCA-COFUND-FP;FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA;IT;;;;1;0;0;2;0;0 215341;795292;SCOUT;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Supporting Causal Conclusions from Observational Survival Studies;2018-10-01;2020-09-30;;The focus of my proposal is on statistical mediation analysis in medical studies with patient survival as outcome. Mediation analysis can help to elucidate the underlying mechanisms and ultimately to alter and further improve components of an intervention or shift the target of an intervention. Specifically, in aim 1 we utilize penalized likelihood techniques in an innovative way to improve mediation analysis with sparse data, e.g. rare side effects of drugs. Aim 2 will focus on the Aalen additive hazards model, an alternative to the Cox proportional hazards model, in particular when causal inference and mediation is of primary interest. We will consider a series of case studies comparing Aalen additive hazards model with the Cox proportional hazards model regarding interpretability of effect estimates, ease of application, applicability of assumptions, ease of description in an interdisciplinary context and public perception. By means of analytical reasoning and empirical studies we fill important gaps in knowledge, while the interdisciplinary working environment and intersectoral seminars will ensure that the achieved advances reach the relevant stakeholders. During the secondment at the Novartis Statistical Methodology Group in Basel, I will get in touch with mediation analysis for interventions in clinical trials and its connections to the estimands framework, which is currently being considered a promising alternative to the intention-to-treat paradigm as first principle in evaluating effects of interventions. The suggested action will combine my supervisor's and my scientific expertise and international experience at its best and thus guarantees mutual growth. Interaction with a highly active research group, participation in the institutional programme for soft skill development and involvement in project administration will further contribute to my development towards independence and are important prerequisites for various career paths.;166156,8;166156,8;H2020-MSCA-IF-2017;/MSCA-IF-EF-RI;MEDIZINISCHE UNIVERSITAET WIEN;AT;;;;1;0;0;2;0;0 214884;787419;SECurITY;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Social-ECological Interdependencies in TransboundarY water resources systems;2019-09-01;2022-08-31;;"More than 286 internationally shared river basins supply 60% of global freshwater. The United Nations and the Council of European Union has highlighted the potential of transboundary water diplomacy. The complex interdependencies between humans and water in these transboundary basins remain poorly understood in the newly proposed discipline of socio-hydrology. Therefore, an assessment of social-ecological interdependencies in transboundary water resources systems is now urgently required for implementing target 6.5 of SDGs and for fulfilling the EU’s commitment on international peace and security. The overall objective of the envisaged research is to develop new understandings of complex human-water systems in large transboundary river basins with an aim to contribute scientific advancement of socio-hydrology and to enhance transboundary cooperation for international peace and security. The proposed research will be hosted in two highly qualified laboratories (during outgoing phase at MIT, with Prof. Susskind and during return phase at UNIVE with Prof. Giupponi). Going beyond the state-of-the-art, the proposed project will develop for the first time: an analytical framework of complex tranboundary water system; comparative network analysis for social ecological systems in two river basins; consideration of negotiation theory and role-play game in developing transboundary cooperation strategies. The proposed project is fundamentally interdisciplinary in characters. The scientifically innovative and socially relevant (for EU and the Globe) proposed project will help me achieve higher levels of professional maturity through innovative research, advanced training, the transferrable skills and interdisciplinary experiences in two highly qualified institutions both at MIT and at UNIVE. These unique experiences will support to achieve my short-(e.g., human-water interactions), medium- (e.g., young investigator) and long-term (permanent position in academia) career goals.";262269;262269;H2020-MSCA-IF-2017;/MSCA-IF-GF;UNIVERSITA CA' FOSCARI VENEZIA;IT;;;;1;0;0;2;0;0 211890;765374;ROMSOC;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2017;H2020;Reduced Order Modelling, Simulation and Optimization of Coupled systems;2017-09-01;2021-08-31;;"The development of high quality products and processes is essential for the future competitiveness of the European economy. In most key technology areas product development is increasingly based on simulation and optimization via mathematical models that allow to optimize design and functionality using free design parameters. Best performance of modelling, simulation and optimization (MSO) techniques is obtained by using a model hierarchy ranging from very fine to very coarse models obtained by model order reduction (MOR) techniques and to adapt the model and the methods to the user-defined requirements in accuracy and computational speed. ROMSOC will work towards this goal for high dimensional and coupled systems that describe different physical phenomena on different scales; it will derive a common framework for different industrial applications and train the next generation of researchers in this highly interdisciplinary field. It will focus on the three major methodologies: coupling methods, model reduction methods, and optimization methods, for industrial applications in well selected areas, such as optical and electronic systems, economic processes, and materials. ROMSOC will develop novel MSO techniques and associated software with adaptability to user-defined accuracy and efficiency needs in different scientific disciplines. It will transfer synergies between different industrial sectors, in particular for SMEs. To lift this common framework to a new qualitative level, a joint training programme will be developed which builds on the strengths of the academic and industrial partners and their strong history of academic/industrial cooperation. By delivering early-career training embedded in a cutting-edge research programme, ROMSOC will educate highly skilled interdisciplinary researchers in mathematical MSO that will become facilitators in the transfer of innovative concepts to industry. It will thus enhance the capacity of European research and development.";2785605,48;2785605,48;H2020-MSCA-ITN-2017;/MSCA-ITN-EID;TECHNISCHE UNIVERSITAET BERLIN;DE;"INSTITUT NATIONAL DE RECHERCHE ENINFORMATIQUE ET AUTOMATIQUE;FRIEDRICH-ALEXANDER-UNIVERSITAET ERLANGEN NUERNBERG;MATHCONSULT GMBH;MICROGATE SRL;FORSCHUNGSVERBUND BERLIN EV;SCUOLA INTERNAZIONALE SUPERIORE DI STUDI AVANZATI DI TRIESTE;UNIVERSITAT LINZ;CONSORCIO INSTITUTO TECNOLOXICO MATEMATICA INDUSTRIAL ITMATI;UNIVERSITAET BREMEN;BERGISCHE UNIVERSITAET WUPPERTAL;POLITECNICO DI MILANO;STMICROELECTRONICS SRL";"FR;DE;AT;IT;ES";;1;0;0;2;0;0 215990;765881;HyFiSyn;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2017;H2020;Hybrid Fibre-reinforced composites: achieving Synergetic effects through microstructural design and advanced simulation tools;2018-06-01;2022-05-31;;The EU has set ambitious goals to reduce greenhouse gas emissions to combat climate change. The transport sector is a major contributor to these emissions, but the targets for this sector cannot be met with currently available materials technology. Due to the direct link between weight and energy consumption, EU investment in advancing lightweight technologies is crucial. Therefore, fibre-reinforced composites are a key technology, but they are not yet widely used due (1) to their high price, (2) overdesign due to a lack of toughness and (3) difficulties with recycling. Addressing these challenges through fibre-hybridisation requires a highly interdisciplinary team of researchers with a strong background in both modelling and experimentation. Since such combined expertise is scarce, HyFiSyn aims to train 13 early stage researchers to become interdisciplinary, multi-talented experts. The 8 universities, 5 industrial partners and 2 professional training organisations offer the researchers a unique opportunity to be trained by world-leading experts in cutting-edge technologies, where they are supported by a strong network and industry participation. The training programme strongly emphasises entrepreneurship and innovation skills to maximise the impact of the project, thereby increasing the EU’s innovation capacity. Simultaneously, the researchers will be trained through research by developing and experimentally validating advanced simulation tools to predict optimal microstructures for fibre-hybrid composites. These microstructures will then be manufactured and verified in industrial applications. To further increase its impact, HyFiSyn also designs hybrids with smart and functional properties, and will investigate strategies for more efficient usage of recycled fibres through fibre-hybridisation. The overall goal is to fundamentally understand synergetic effects, so that they can be maximally exploited and unprecedented composite performance can be achieved.;3371703,12;3371703,12;H2020-MSCA-ITN-2017;/MSCA-ITN-ETN;KATHOLIEKE UNIVERSITEIT LEUVEN;BE;"SIOEN INDUSTRIES NV;IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE;UNIVERSITAT WIEN;ELG CARBON FIBRE LIMITED;BUDAPESTI MUSZAKI ES GAZDASAGTUDOMANYI EGYETEM;ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE;NORTH THIN PLY TECHNOLOGY SARL;DANMARKS TEKNISKE UNIVERSITET;THE UNIVERSITY OF NOTTINGHAM;BAYERISCHE MOTOREN WERKE AKTIENGESELLSCHAFT";"BE;UK;AT;HU;CH;DK;DE";;1;0;0;2;0;0 207670;706172;NanoToX;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Does climate change enhance the nanoparticle toxicity of freshwater biofilms?;2017-01-09;2019-08-30;;"Aquatic ecosystems are threatened by multiple environmental stressors including pollutants and climate change. Considerable progress has been made in understanding the environmental impact of many stressors in recent years, yet new, potentially powerful, toxicants such as engineered nanoparticles (ENPs) continue to emerge in aquatic systems and their effects on these ecosystems remain poorly understood. The release of ENPs into the environment is accelerating , and as the global climate warms, the combined effects of both stressors (ENP \ temperature increase) could have significant consequences for aquatic life. As a major step into understanding the climate change-enhanced environmental impacts of ENPs in aquatic ecosystems, we focus on the responses of fluvial biofilms -microbial consortia that drive aquatic primary production and respiration and thus, control nutrient conditions - as key points of ENP entry in to aquatic food webs. The central goal of NanoTOX is to elucidate how much river warming will affect fluvial biofilms at genetic, metabolic/functional and structural levels, and how the presence of environmental concentrations of ENPs may further stress the communities. The combination of multiple stressors (increased temperature and ENP) is expected to have a profound influence on the fluvial biofilms performance. This objective will be achieved through an innovative, interdisciplinary approach using an array of methods from the fields of ecotoxicology (ecology and toxics), molecular, functional ecology and nanotechnology will be applied. The proposed interdisciplinary study is a major first step in opening a new research field focussing specifically on biofilms as entry points to the food web and assessing ENP impacts under future climate scenarios. NanoTOX project results therefore will provide valuable information to underpin current updates to European legislation, ENP industry and will address social challenges.";183454,8;183454,8;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;THE UNIVERSITY OF BIRMINGHAM;UK;;;;1;0;0;2;0;0 214702;772354;JUSTINT;SIGNED;H2020-EU.1.1.;ERC-2017-COG;H2020;Justice Interactions and Peacebuilding: From Static to Dynamic Discourses across National, Ethnic, Gender and Age Groups;2018-09-01;2023-08-31;;"JUSTINT will provide a novel way of analysing how post-conflict justice practices, such as war crimes trials and truth-seeking, advance or hinder peacebuilding. It breaks away radically from existing approaches and examines an interactive and dynamic aspect of discourse. Until now, we have relied on statements by politicians, civil society actors, or victims to understand their response to post-conflict justice, and studied them as static discourses. Instead, we need to investigate communicative exchanges to understand how discussions about the violent past unfold, and to what effect. JUSTINT asks: how do people interact with each other in response to post-conflict justice across national, ethnic, gender and age groups in different deliberative domains? Do their views change in these interactions, and how? Written and spoken communication can provide strong evidence of attitudes and of their transformation. JUSTINT will apply Quantitative Text Analysis and Conversation Analysis to interactions in face-to-face and virtual deliberative domains (courts, parliaments, civil society debates, blogs, Web-based comments, and Twitter). This mixed-method research will deliver fine-grained multi-language empirical analysis of patterns of discourse in four former Yugoslav countries (Serbia, Bosnia and Herzegovina, Kosovo and Croatia), selected as a typical case of post-conflict justice practices. It will be carried out by an interdisciplinary team (three political scientists with expertise in peacebuilding, post-conflict justice and political behaviour, a gender specialist, a computational linguist and a quantitative text analyst). JUSTINT will generate a theory of justice interactions, and open up significant new research horizons at the intersection of peacebuilding and deliberation. It will break new ground by studying justice discourses at the level of words and conversational sequences through interdisciplinary integration and methodological innovation.";1976260;1976260;ERC-2017-COG;/ERC-COG;LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE;UK;;;;1;0;0;2;0;0 215853;801481;iMED;SIGNED;H2020-EU.1.3.4.;MSCA-COFUND-2017;H2020;International Doctoral Programme in Molecular Mechanisms of Disease;2019-04-01;2024-03-31;;The International Doctoral Programme in Molecular Mechanisms of Disease (iMED) will recruit 24 international doctoral fellows to Biotech Research and Innovation Centre, University of Copenhagen. iMEDs VISION is that the next generation of researchers should possess the abilities to perform and connect excellent science to exploitation and value for the surrounding society. Our MISSION is to foster a cohort of excellent fellows through a personalized research and training programme, ensuring that they exploit the full potential of their talents. iMEDs procedures and activities will provide a structural and intellectual framework for the fellows to develop strong research and transferable skills and empower diligence, ambition and creativity, as well as competences to build their individual research career. We will implement interdisciplinary research projects, transnational mobility and intersectoral exposure, ensuring improved employability of fellows across fields, borders and sectors. The EU Principles of Innovative Doctoral Training and the Code of Conduct for the Recruitment of Researchers serve as a platform for iMED and form the ground for the programme aims: ensure transparent merit-based selection of candidates, 2) nurture development of excellent interdisciplinary research competences, 3) ensure inter-sectoral exposure, 4) ensure international networking, 5) provide transferable skills training and a personalised career development programme and 6) provide timely expert supervision and mentoring. Three private Partner Organisations will supply transferable skills training and career activities. An alliance of 13 top life science research institutes will provide secondments, co-supervision and PhD courses. Four international experts will participate in the selection of fellows and form a Training Advisory Board. The programme will be professionally led by Prof. Anders H. Lund, Head of BRICs national PhD programme and coordinator of the FP7 ITN RNAtrain.;3767040;1883520;H2020-MSCA-COFUND-2017;/MSCA-COFUND-DP;KOBENHAVNS UNIVERSITET;DK;;;;1;0;0;2;0;0 214958;789551;HMAM;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Healing Multiphysics of Asphalt Materials;2018-08-01;2020-07-31;;HMAM aims to train a talented research Fellow through an interdisciplinary project focused on modelling the coupled healing multiphysics in asphalt materials (AMs) including the processes of chemical bonding, mechanical responses, environmental condition variations and microstructural morphology changes. The primary deliverables resulting from the HMAM include a better understanding of AMs’ healing mechanisms, an accurate performance prediction framework and evaluation protocol for healing-capable AMs, and an implementation of healing materials and technologies in sustainable road construction. Through the research, the Fellow will receive intensive technical training in multidisciplinary field of chemistry (Aston), material science (Aston), computational modelling (Aston, TUD), experimental characterization (UoN) and industrial applications (Nynas and AI). The Fellow will also receive inter-sectoral and professional skills training in project management, outreach, networking and intellectual property protection. The benefits brought by HMAM is represented by strengthening the EU industry leadership in healing material innovation and aiding the EU engineers in asphalt material selections, road structural design and techno-economic analysis. The implementation of healing-capable asphalt materials in road infrastructures will extend the road service life and ultimately reduce the greenhouse gas emissions and save natural resources like petroleum bitumen and mineral aggregates. Uniquely, the project will enable the Fellow to obtain interdisciplinary knowledge and inter-sectoral complementary skills by building a new and exciting research field, which will pave a solid foundation for the Fellow towards his career of being an independent expert researcher in the areas of infrastructure sustainability and construction materials at a top European university.;195454,8;195454,8;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;ASTON UNIVERSITY;UK;;;;1;0;0;2;0;0 215462;796601;PISA;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Political Instruction in the Soviet Armed Forces: Civil-Military Relations in War and Socialist Construction, 1918-1942;2018-09-01;2020-08-31;;"This research project will provide a detailed account of the development and functioning of the Soviet institutions of civilian control over the military: the parallel hierarchy of political officers of the Political Directorate of the Red Army and the Communist Party organisations operating in the Soviet Armed Forces. Drawing on the interdisciplinary social science field of Civil Military Relations (CMR) it will investigate the nature of the relationship between party organisation, regular and political officers and provide an assessment of the impact of this arrangement on relations between officers and enlisted men and women as well as combat readiness and effectiveness during the Russian Civil War and the early stages of the Second World War. It will further offer an evaluation of this system as a means of civilian control over the military within the specific context of the Soviet state-building project in the interwar period. The origins of the Red Army as a paramilitary sub-state actor will be placed at the centre of the analysis. This project will thus contribute to multiple literatures, including the history of Stalinism and the history of military politics in interwar Europe, as well as the social science CMR literature. This research action will be pursued at the interdisciplinary Centre for War Studies of University College Dublin under the supervision of Professor Robert Gerwarth. Training objectives to be pursued during this project include familiarisation with the social science field of CMR as well as the development of the skills necessary to reach a position of professional maturity as a world-class researcher. The hosting institution will provide training in effective publication and collaboration strategies as well as mentorship and supervision of students. As the hosting institution is located in a different country to the one where the researcher is currently based, this project will also offer significant networking opportunities";175866;175866;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN;IE;;;;1;0;0;2;0;0 214526;798371;DSMFACIL;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Facilitating a digital single market in Europe through cross-border alliances;2018-09-01;2020-08-31;;"“Nearly all growth in retail comes from e-commerce” states E-commerce Europe, as online sales in Europe grew by 13.3% while the growth in total retail sales merely reached 1% in 2015. However, cross-border sales constituted only 10.6% of Europe's total online sales in 2013, despite the European Commission’s (EC’s) estimate of €415 billion annual contribution to European economy from a European Digital Single Market (DSM), which is currently one of the top priorities of the EC. Besides language barriers and differences in legislature across the EU, the EC states that low engagement can be attributed to: 1) high compliance and delivery costs, 2) low consumer trust regarding foreign retailers’ delivery and after-sales support, and 3) low consumer awareness of foreign retailers. The EC has proposed several trade policy measures to facilitate a DSM. Yet, complementary operational business strategies that enable cross-border profitability under aforementioned challenges have not been explored, while trade measures are still under way. This project aims to develop an interdisciplinary modeling and optimization framework in order to study the dynamics of cross-border alliances between retailers for enhanced cross-border customer acquisition, distribution, and after-sales support. This much-needed framework will provide timely and reproducible models, leading to win-win horizontal cross-border alliances that leverage unique strengths of local retailers under high distribution and compliance costs, low cross-border consumer awareness, and consumer concerns on cross-border delivery and after-sales support. To that end, an interdisciplinary research that uses econometrics, economics, systems dynamics, and optimization literatures will be conducted to create models that can be translated into decision support systems. The proposed models will find future applications in banking and travel sectors, as they face similar challenges in their cross-border operations.";165598,8;165598,8;H2020-MSCA-IF-2017;/MSCA-IF-EF-RI;TECHNISCHE UNIVERSITEIT EINDHOVEN;NL;;;;1;0;0;2;0;0 215110;792969;GenderQuotas;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Gender Quotas and the Democratic Quality of Local Decision-Making Processes in Clientelistic Regimes;2018-09-01;2020-05-31;;Gender quotas are a widespread electoral reform aiming to tackle gender inequality in politics. A rich body of literature focuses on the impact of gender quotas on the articulation of women’s interests in national legislatures. Yet we know very little about the transformatory potential of gender quotas for local decision making. Do gender quotas challenge existing practices of local decision making and advance democratization in clientelistic regimes? This research project investigates the impact of gender quotas on the democratic quality of local decision-making processes in Albania. Do women push for transparency, accountability, and responsiveness? How does women’s engagement in local decision-making processes change over time? The project offers a unique and innovative perspective into the topic of gender quotas and democratization through the combination of theoretical and methodological approaches, original data, interdisciplinary approach, and comprehensive public engagement and dissemination of research findings. The proposal relates with a novel interdisciplinary approach that draws on studies of democratization, representation, political anthropology, and feminist institutionalism. The project will enhance the knowledge and skills of the Experienced Researcher by providing state-of-the-art training in data analysis and management – Python Programming Language and ATLAS.ti – advanced knowledge of theoretical and methodological approaches, and scientific and transferable skills. The knowledge and skills combined with networking and collaboration will place the Experienced Researcher in a competitive position among successful researchers in Europe.;152125,05;152125,05;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;UPPSALA UNIVERSITET;SE;;;;1;0;0;2;0;0 214567;793559;EMOMETER;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;EMOMETER: Developing an Integrated Toolbox for the Assessment of Emotional Functioning in Dogs;2018-10-01;2020-09-30;;Dogs have great social (e.g. companion dogs) and economic (e.g. working, assistance, therapy dogs) values. Their increasing presence in our society (~63 million in Europe and 500 million worldwide) calls a timely understanding of emotional processing in dogs, in order to promote human-dog bonds, ensure dog welfare and reduce dog related costs to society (e.g. dog-bite related incidents). Emotional functioning is a complex process and we currently have very little understanding of it in non-human animals, with no consensus on the theoretical framework and limited robust empirical research on dog emotion. Given recent theoretical advances (e.g. multi-component emotion process theory) in human emotion research and improved technology (e.g. integrated wearable wireless sensors), there are new opportunities to address this fundamental issue. This interdisciplinary research programme will break new ground by developing an integrated toolbox (a range of behavioural, cognitive and physiological measures) for emotion assessment, and providing the first systematic study of multi-component emotional functioning in dogs. The novel findings will result in a step change in our understanding of dogs’ capability for processing and functionally responding to emotional signals, such as subtle or even subliminal human expressions. This has significant practical implications for various human-dog interactions and dog welfare. The development of such an integrated toolbox for dogs will pave the way for emotion assessment in a variety of animal species in everyday settings and will ensure Europe remains at the forefront of animal emotion and welfare research. With combined expertise in animal cognition, behaviour and welfare, cognitive neuroscience and computer science, the interdisciplinary supervisory team will provide structured training of research and complimentary skills to the Fellow, and facilitate her development as a future leader in this emerging field.;183454,8;183454,8;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;UNIVERSITY OF LINCOLN;UK;;;;1;0;0;2;0;0 215533;797338;ORBETEC;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;ORganisational BEhaviour with new TEChnologies: a human resources management model for industry 4.0;2018-09-17;2020-09-16;;"Research related to the fourth Industrial Revolution is growing up and are a major asset for prosperity and European economic growth. However, the effect of human resources management in relation to industry 4.0 remains few investigated in the field of Work and Organizational Psychology. In view of the constantly evolving dynamics favouring the implementation of new technologies in organizations (autonomous robots, virtual reality, big data, and so on), it is now essential to define a model adapted to industry 4.0. The objective of ORBETEC project is to generate a model of human resources management, targeting four essential areas (organizational development, professional development, competence development, and compensation/reward), applied to the reality of industry 4.0. The research will take place in Foligno (IT) in a highly technological organization, the Umbra Cuscinetti S.p.A (Umbra Group headquarters), world leader in the production of recirculating ball screws in the aeronautic sector. Beatrice Baldaccini (Supervisor) and Carlo Odoardi (Professor Key person) will provide researchers’ supervision and training. The use of a qualitative and quantitative methodology via multilevel and longitudinal statistics will allow the study of the organizational behaviours generated inside evolving and highly innovative organizations. Two secondments will be determined in order to strengthen the international and interdisciplinary aspect of the ORBETEC project. ORBETEC will be one of the few researches to explore Industry 4.0 in the field of organizational behaviour and will contribute to the definition of an international human resource management model. The results will be disseminated in peer-reviewed international journals and interdisciplinary training will propel the researcher at European expert level. Finally, ORBETEC will improve the performance, productivity and work-life quality of a company with an economic impact at regional, national and European level.";168277,2;168277,2;H2020-MSCA-IF-2017;/MSCA-IF-EF-SE;UMBRAGROUP SPA;IT;;;;1;0;0;2;0;0 214826;786560;NanoMop;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Smart Cholesterol-Mopping Polymer Nanoparticles in Niemann-Pick Disease Type C;2018-04-01;2020-03-31;;Niemann-Pick Disease Type C (NPC), also known as “childhood Alzheimer’s”, is a rare genetic disorder caused by the accumulation of cholesterol particularly in the brain with subsequent cognitive and mobility decline. In the EU NPC has an incidence of 1 per 100,000 people. Most cases are detected during childhood and progress to cause life-threatening complications by the second or third decade of life. Cyclodextrins (CDs), a family of naturally occurring sugars, have recently gained considerable attention as a potential therapeutic intervention in the treatment of the disease because of their capacity to sequester cholesterol. Although promising, the current treatment of NPC based on a chemical modification of bCD suffers from poor pharmacokinetics and bioavailability in the brain. In this project I propose a new interdisciplinary approach in which bCDs will be embedded into a novel class of smart polymer nanoparticles (NanoMops) that could overcome these limitations. The project addresses an important question that needs to be answered urgently and its successful completion will contribute to the treatment of the neglected disease in line with the Horizon2020 health goal of providing better and more effective therapies. My specific skillset in chemical modification of CDs puts me in a unique position to successfully carry out this project. This interdisciplinary proposal is designed to provide me with advanced training in macromolecular chemistry and in a range of cutting-edge biological techniques. The fellowship will significantly diversify my competences and broaden my profile – professionally and personally - enabling me to pursue a career as an internationally recognised independent researcher. The project will also create new important international and inter-sectoral partnerships with excellent academic and industrial players while reaching out to charity organisations, raising awareness and networking researchers and key stakeholders in the area of NPC.;145845,6;145845,6;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;ISTANBUL TEKNIK UNIVERSITESI;TR;;;;1;0;0;2;0;0 214363;793853;BUDDHISMAFRICA;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;East-Asian Buddhism in Post-Apartheid South Africa;2018-06-01;2020-05-31;;Explorations of Buddhism in Africa are very few and have been so far conducted at the introductory level. Moreover, in the field of religious studies there is still a marked tendency to reduce the globalization of Buddhism to its worldwide missionary activities, and to neglect crucial factors such as the impact of deterritorialization and hybridization. BUDDHISMAFRICA aims to break new ground in this field of research by approaching these dynamics from an interdisciplinary perspective at the intersection of religious studies, sociology, anthropology, media studies, African studies, East Asian studies, gender studies, and global studies, as to provide for the first time a comprehensive and detailed analysis of East Asian Buddhism in South Africa, with a focus in the post-apartheid period (1994-present). BUDDHISMAFRICA has three research objectives, which will be pursued through ethnographic (participant observation, in-depth interviews) and archival research: 1) To analyze the trajectory of East Asian Buddhism in South Africa and its hybridization at the organizational/individual level. 2) To investigate the degree in which East Asian Buddhism has been able to reach out to black people, and to provide them with maps to navigate race and cultural identity. 3) To clarify the impact of informal spiritualities related to East Asian Buddhism on the South African religious context. BUDDHISMAFRICA will disseminate the research findings through peer-reviewed open-access publications (two articles and one monograph), an international workshop (and the publication of its proceedings), public talks for non-specialists, and project updates through the traditional/social media. Moreover, BUDDHISMAFRICA has put in place a detailed training program that is aimed, in collaboration with the supervisor/internal advisors and through the participation in dedicated workshops, to develop the applicant’s interdisciplinary, research management, teaching, and interview skills.;195454,8;195454,8;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;CARDIFF UNIVERSITY;UK;;;;1;0;0;2;0;0 215305;794958;SufiVisual;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;THE VISUAL CULTURE OF SUFISM IN FRANCE AND GERMANY;2018-07-01;2020-06-30;;Sufism, the mystical path within Islam, is spreading extensively throughout European society. However, despite its growing significance, we know little about the religious visual culture of ‘mystical Islam’ or Sufism, and no comprehensive study for the visual culture of Sufi orders in Europe exists, constituting a major gap in our knowledge. The proposed two-year research project SufiVisual will fill this gap. Combining anthropology, ethnography, religious studies, gender studies, and art history, the study will apply an innovative interdisciplinary approach to generate unprecedented insights into the visual culture of three key Sufi-based organizations. In combination these create a balanced case study in two research fields, France and Germany, which can be seen as paradigmatic for the European situation and beyond, narrowing the scope of the project so that it is feasible within the timeframe proposed while establishing a foundation for future projects to expand and build upon. The project will break new ground by being the first comprehensive interdisciplinary study on Sufi visual culture in a transnational context. It will produce pioneering work on gender-specific Sufi visual culture and contribute important scientific data on Sufi visualizations of belief and piety. The research findings will identify the ways in which visual culture actively constructs and shapes religious concepts and impacts our understanding of Islam, secularism, and European identity. A central working hypothesis of this project is that visual culture and religious practice is a counter movement to religious fundamentalism and a driving force for religious pluralism.;173076;173076;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FR;;;;1;0;0;2;0;0 215762;799805;SECCON;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Security controversies: exploring the governance of knowledge, innovation and techno-scientific risks;2018-05-01;2020-04-30;;"The EU is one of the key proponents of knowledge-based economy, i.e. an economic system based on research, development, and knowledge production. However, techno-scientific progress may bring not only benefits and well-being to the society, but also undesired side-effects and new dilemmas. Apart from social, ethical, or environmental controversies that scientific research opens, innovation is now increasingly linked with security controversies, characterized by the concerns over a potential misuse of science for hostile purposes. Yet with the ever-accelerating speed of scientific inquiry and the rise of interdisciplinary and international connections, it becomes impossible to clearly define and police “dangerous” research that could be exploited by terrorists and criminals. To balance the demands for scientific openness with national security interests, new techniques of governance are introduced in science, which integrate the existing principles of scientific responsibility with security practices restricting the mobility of scientific knowledge. This project aims to build a unique body of interdisciplinary expertise to study security controversies in the governance of research and innovation. It will link researchers from security studies and science and technology studies with leading biotechnological stakeholders in Austria and practitioners of Responsible Research and Innovation (RRI) involved in ethics review of EU research projects. Specifically, the project will, first, situate the current security controversies historically and theoretically, second, map the techniques of knowledge governance in health-data governance and RRI, and third, explore what competences and skills are required in the assessment of security risks of scientific knowledge mobility in the two empirical areas. In sum, the project will set out a research agenda to study how our societies design, implement, and regulate sensitive and potentially dual-use research and innovation.";178156,8;178156,8;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;INSTITUT FUER HOEHERE STUDIEN - INSTITUTE FOR ADVANCED STUDIES;AT;;;;1;0;0;2;0;0 215224;794048;FINISTERRAE;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;NEGOTIATING AND CONTESTING MARGINAL LANDSCAPES ON THE WESTERN FRINGES OF THE ROMAN EMPIRE;2019-09-01;2021-08-31;;Finisterrae adopts a state-of-the-art landscape archaeology approach to reassess the changing character of Roman imperialism and its impact on local landscapes and societies on the western fringes of the Roman Empire. The peripheral landscapes of NW Iberia and SW Britain, previously interpreted as marginal, will be explored as examples of alternative imperial narratives and as landscapes of opportunities, through a bespoke interdisciplinary methodology. This integrates archaeology, remote sensing and palaeoecology and is aimed at natural and cultural proxies, in order to deliver an innovative inter-provincial, multiscalar and multivocal, yet holistic understanding of these landscapes. It will (a) allow a broad scale understanding of the strategies and the impact of Roman imperialism, and of the discrepant responses of native societies, and (b) shed new light on the Roman conquest and provincial organisation in the Roman frontier. This will be achieved by building upon the applicant’s previous research and expertise in Roman and aerial archaeology and enhanced by new skills he will acquire in ground-based landscape approaches. This training-through-research project at Exeter University, with its unique integral range of expertise in landscape archaeology from paleoenvironmental to ground and above-ground approaches will enable the applicant to receive high-quality training. The contributions of Finisterrae to understand the processes leading to social change, marginality and border-related socio-environmental stress are extremely timely in today’s worldwide order. Several high-impact publications and further dissemination beyond the academic environment will increase the impact of the project and contribute, alongside newly acquired skills and experiences, to enhance the researcher’s future interdisciplinary and international career perspectives in line with the Horizon 2020 Programme’s aims to promote EU excellence through top research and a knowledge-based society.;195454,8;195454,8;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;THE UNIVERSITY OF EXETER;UK;;;;1;0;0;2;0;0 215050;792197;FIRE;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Fire Impacts in Rainforest Ecotones;2019-08-01;2021-07-31;;Amazonian rainforest ecotones (AREs) are one of the most heavily exploited and most threatened ecosystems in the Amazon. Fire plays an integral role in maintaining these vegetation transition zones from fire-averse rainforest to fire-prone savanna vegetation. Synergies between direct human activity and indirect climate change impacts threaten to accelerate forest transformation through positive feedback loops by increasing future fire susceptibility, fuel loads and fire intensity. As regional precipitation is expected to decrease due to deforestation and reduced evapotranspiration, and natural- and human-caused ignitions are projected to increase fire in AREs. The combined results will likely drive the expansion of savanna forests at the expense of the rainforest vegetation. AREs have largely been neglected in fire management strategies and the long-term ecological effects of fire in AREs remain poorly understood. Therefore, there is an urgent need to understand the long-term effects of climate variability and human disturbance on fire in these vital ecosystems to inform future land-management and conservation efforts. The objective of this proposal is to determine the natural and human-caused drivers of fire in the Bolivian ARE for the past 8,000 years. I have thus developed a state-of-the-art interdisciplinary framework integrating high-quality palaeoecological, palaeoclimatological data with current archaeological survey data to provide long-term records of natural variability and human land-use change. These new data will be incorporated into various scenarios in statistical Structural Equation Models to investigate natural and human factors driving fire in AREs for the past 8 thousand years. I will develop a case study for proof-of-concept of a new interdisciplinary framework that will result in a greater understanding of the long-term drivers of fire in AREs and inform how future climate and changes in land-use practices may impact these vital ecosystems.;165598,8;165598,8;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;UNIVERSITEIT VAN AMSTERDAM;NL;;;;1;0;0;2;0;0 215852;801538;CONEX-Plus;SIGNED;H2020-EU.1.3.4.;MSCA-COFUND-2017;H2020;CONcentrating EXcellence in UC3M - Postdoc Programme;2019-03-01;2024-02-29;;"CONEX-Plus is a training and mobility program that aims to accelerate the career development of a cohort of Experienced Researchers at UC3M in Spain. CONEX-Plus will offer 30 fellowships of 36 months each, for incoming mobility to UC3M. Building on the excellence of UC3M, the program will develop the next generation of research leaders in the strategic research areas that are identified in the Research and Innovation Strategy for Smart Specialisation (RIS3) strategy of the Madrid Autonomous Region, underpinned by Social Sciences and Humanities. The principles of the Charter and Code are applied throughout the program. Applicants will submit proposals on research topics freely chosen by them. There will be two calls where fellows will be selected following an open, transparent, merit-based, impartial and equitable selection procedure, based on international peer review and interviews. Training is received through the implementation of an individual interdisciplinary research project under guidance of a supervisor. Secondments are compulsory and will be supported by 12 non-academic and 2 academic entities. All fellows will participate in the CONEX-Plus training program, with dedicated modules on relevant transferable skills and Industry Training Blocks. The career development of all fellows will be supported by the use of a Career Development Plan and through regular supervision meetings. The interdisciplinary research program will provide fellows with excellent scientific and relevant transferable skills to communicate across and between research disciplines. Fellows will also learn how to work in and between different sectors. Both are requisites for achieving most future relevant scientific and industrial results. CONEX-Plus equips researchers with skills and expertise in research areas that are of strategic importance to UC3M, the Madrid region and Europe who will contribute to address future challenges for the benefit of European citizens and society.";6372000;3186000;H2020-MSCA-COFUND-2017;/MSCA-COFUND-FP;UNIVERSIDAD CARLOS III DE MADRID;ES;;;;1;0;0;2;0;0 214964;789632;SAFVEN;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;West meets East in Venice: Cross-cultural interactions and reciprocal influences between theSafavids and Venetians;2019-01-15;2021-01-14;;In the last two decades, in the wake of the renewed interest in early modern diplomacy and shifting toward interdisciplinary and transcultural approaches, the interactions between Europe and the Islamic Middle East have received considerable attention. Scholars are increasingly emphasizing interconnected and shared history of Europe and the Middle East. The nature of these connections can be traced through the comprehensive examination of early modern cross-cultural encounters between the Islamic Middle East (Ottomans, Safavids) and Europe (Venetians). While the history of the diplomatic relations between the Safavid Empire and Venice has been relatively well studied, its cultural impact, especially the material dimension of diplomatic encounters has been largely neglected. Despite a 'cultural turn' in the history of diplomacy and a growing interest in symbolic communication in diplomatic practices, there remains little scholarship on importance of ritual and ceremony in Safavid-Venetian diplomatic relations. No attempt has been made to study in a systematic way the cultural and political meanings of gifts, reciprocity in gift exchanges, connections between gifts and identities, institutional, ceremonial and economic aspects of material exchanges in Safavid-Venetian diplomatic encounters. The proposed research aims to explore a largely neglected subject – the significance of symbolic communication, ritual and ceremony in Safavid-Venetian diplomatic relations and a material dimension of the Safavid-Venetian diplomatic encounters, which is essential for a better understanding of cross-cultural interactions between two empires. The project will allow me to acquire new skills (codicological analysis of manuscripts, Latin and Italian palaeography) and improve my existing skills (archival research, interdisciplinary use of sources, project management).;180277,2;180277,2;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;UNIVERSITA CA' FOSCARI VENEZIA;IT;;;;1;0;0;2;0;0 214069;770870;MOOiRE;SIGNED;H2020-EU.1.1.;ERC-2017-COG;H2020;Mix-in Organic-InOrganic Redox Events for High Energy Batteries;2018-09-01;2023-08-31;;"The ever-increasing demand for improved electrochemical energy storage technologies has fostered intense, worldwide and interdisciplinary research over the past decade. The field of positive electrode materials remains largely dominated by transition metal compounds in which only the redox of metal cations contributes to the energy storage. The development of new materials and technologies, wherein both anions and cations display reversible, multi-electron redox, is bound to strongly impact this field. MOOiRÉ will challenge this goal through innovative approaches on Metal Organic Compounds and Frameworks (MOC/Fs) with mix-in many-electron reversible redox of both, transition metal cations and organic ligand anions. Building on our preliminary results MOOiRÉ will adopt an integrated approach. We will combine performance oriented MOC/F molecular design supported by in-operando analytical inspection tools with novel electrode engineering approaches to overcome the limitations and enable efficient electrochemical charge storage. Through this highly interdisciplinary research, MOOiRÉ intends to advance the science and technology of mix-in redox MOC/Fs for next generation batteries, supercapacitors and their hybrids. MOOiRÉ will also be a major systematic study of the fundamentals of MOC/F-based energy storage systems in view of a practical implementation. The overall impact will extend beyond the energy science community: the developed knowledge, tools and procedures will influence research and development related to porous composite materials, sorption, ion exchange and electrocatalysis. In the context of energy storage, this will be a disruptive development, enabling the use of MOC/Fs electrodes, with superior levels of performance as compared to current technology, at affordable costs and based on novel protocols.";1997541;1997541;ERC-2017-COG;/ERC-COG;UNIVERSITE CATHOLIQUE DE LOUVAIN;BE;;;;1;0;0;2;0;0 213398;758636;PalREAD;SIGNED;H2020-EU.1.1.;ERC-2017-STG;H2020;Country of Words: Reading and Reception of Palestinian Literature from 1948 to the Present;2018-04-01;2023-03-31;;"This project proposes a deep and thorough study of Palestinian literature as an early and on-going case of literary displacement. It aims to find new ways to account for and analyse texts, literary production and reading publics that challenge and lie outside conventional conceptions of the nation-state. The proposed methodology will take a novel approach in merging textual analysis with reception theory and reading practices. The project is ambitious in seeking to be the first instance to explore its application on the scale of an entire ‘literature-of-a-nation’. By doing so, the project aims to introduce methodological innovations that can expand horizons beyond textual and national analyses towards interdisciplinary models that contend with the multi-faceted and unconventional dimensions of the Palestinian case, and generate a richer and more nuanced history of its literature. The proposed project will explore, for the first time under one analytic roof, all the geographic fragments of Palestinian literature together, traditionally studied separately, or limited to certain authors or time periods. The project’s novelty also lies in broadening the horizons of literary analysis towards an interdisciplinary and transmedial approach that embeds literary production into a wider cultural web of intersecting media and genres. A creative approach will be developed to overcome the hurdles of working, in the Palestinian case, with few scholarly precedents, and scattered, lost or damaged primary and secondary sources. The project’s four work packages will trace connections and disconnections and transformations of publics and reading practices across dispersed Palestinian literary communities of writers and readers over time. The focus will be on identifying, tracing and elaborating key and/or turning point moments across the various localities of the Palestinian literary sphere. An online platform will visual, digitalize and make accessible the project’s outputs.";1493439;1493439;ERC-2017-STG;/ERC-STG;FREIE UNIVERSITAET BERLIN;DE;;;;1;0;0;2;0;0 209853;754489;ALECS;SIGNED;H2020-EU.1.3.4.;MSCA-COFUND-2016;H2020;Advanced Learning in Evolving Critical Systems;2017-07-01;2022-06-30;;"Globally, software-based systems are increasingly important to economic activity and to the normal functioning of our everyday lives. The scope, scale and interconnected nature of such systems are increasing rapidly, with the potential consequences of failure, security breaches or malfunction becoming a growing cause of concern. Evolving Critical Systems (ECS) that change over time (“evolving”), and strategically important to their users (“critical”), are increasingly prevalent in software development, from business-critical systems (e.g. airline websites) to safety-critical systems (e.g. automotive braking control system). Advanced Learning in Evolving Critical Systems (ALECS) is an innovative fellowship programme providing intersectoral and interdisciplinary training in strategic priority areas in software research. The aim of ALECS is to develop the next generation of skilled researchers who will gain hands-on experience developing cross-disciplinary and entrepreneurial skills through individual research projects with a mandatory 3-6 month intersectoral secondment to an industry partner during their fellowship. The ALECS Programme will fund 26 two-year incoming fellowships to Ireland in the area of ECS, with fellows will be recruited during 2 calls for proposals over the 54 month duration of the project. ALECS thus will generate a diverse, mobile, skilled workforce and will contribute to European research and innovation. While developing young researchers, ALECS will directly contribute to sustainable economic growth through supporting evidence-based research to drive innovation and new product development. ALECS will provide the international mobility, intersectoral exposure and interdisciplinary research opportunities that are essential to develop the scientific leaders of tomorrow.";3681600;1840800;H2020-MSCA-COFUND-2016;/MSCA-COFUND-FP;UNIVERSITY OF LIMERICK;IE;;;;1;0;0;2;0;0 209215;746168;AGenDA;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Civil society organizations and the politics of long-term care reform: coalitions and multiple inequalities;2018-01-01;2019-12-31;;Population ageing and gender inequality are cross-cutting political and societal challenges facing Europe. AGenDA meets this challenges by implementing novel and interdisciplinary state-of the-art research on the interaction between multiple intersecting inequalities in Long-Term Care (LTC) reforms. It focuses on the impact of civil society organizations (CSOs) mobilizing around gender, age and disability in reform coalitions in Italy and Spain. Through research and public engagement, AGenDA’s strives to promote inclusive equality in LTC systems, thereby contributing to meet Horizon 2020 challenges “Health, demographic change and wellbeing” and “Inclusive, Innovative and Reflective societies”. By engaging civil society, it promotes participation and effectiveness of social actors in decision-making processes as highlighted in Europe 2020 strategy. By focusing on countries which are laggards in the development of LTC and gender equality policies, AGenDA produces and disseminates knowledge on the social and political obstacles that impede the development of fair and inclusive LTC systems, thereby strengthening integration and cohesion within the European Union. In line with MSCA objectives, AGenDA includes a comprehensive training plan to enhance the future career opportunities and inter-sectoral employability of the researcher. These objectives will be achieved through excellent training-through-research, an academic secondment developing new interdisciplinary and methodological competencies and a non-academic secondment providing access to policy networks and on-the-job-training in outreach and public engagement. The ambitious dissemination and communication plan aims at enhancing the international visibility of the project, promoting knowledge-transfer between all actors involved, and producing wider impact on EU institutions, policy-makers, CSOs, academics and the general public.;180277,2;180277,2;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;SCUOLA NORMALE SUPERIORE;IT;;;;1;0;0;2;0;0 208602;747082;AGORA;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Alternative Grassroots Organizations as a Response to Austerity: perspectives from Southern Europe;2017-06-01;2019-05-31;;"In recent years the global financial crisis and the consequent austerity measures have triggered protest movements all over the world. In Southern Europe there has been a strong wave of mobilizations directed to defend public welfare provision. These anti-austerity movements have been characterized by a call for social justice framed in solidarity and inclusion, against the perception of a reduced capacity by the state of addressing citizens’ needs. This low level of trust in institutional politics has triggered the creation of alternative spaces of deliberative and participatory democracy, directed to experiment with different political expressions. A crucial question is whether and how this claim for different forms of democracy has been translated by social movements into organizational forms that bring increased democracy also into the economic sphere. In order to address this still underinvestigated issue, AGORA focuses on those entrepreneurial activities that originate from the civil society, in this specific case as a direct expression of anti-austerity movements, that are characterized by the prevalence of social objectives over profit maximization. AGORA will investigate the organizational dynamics and characteristics of Social and Solidarity Economy (SSE) organizations that emerged in Spain and Portugal in the aftermath of the financial crisis. The general objective of AGORA will be to assess how SSE is politically framed by investigating the linkages between social movements and SSE. Starting from a social movement perspective, AGORA will adopt an interdisciplinary approach, by finding synergies between social movement scholarship, economic anthropology, organization studies and SSE scholarship (which is per se interdisciplinary), with the aim of integrating different approaches proposed by these disciplines.";160635,6;160635,6;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;CENTRO DE ESTUDOS SOCIAIS;PT;;;;1;0;0;2;0;0 208902;746768;INCRICO;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;The International Criminal Court and the Judicial Function: a Socio-Legal Study of Judicial Perceptions and Practices;2018-09-01;2020-08-31;;"INCRICO investigates the ways in which the International Criminal Court (ICC) perceives its judicial function and how this impacts its legal practices. The overall goal is to offer a realistic account of the international criminal judiciary with regard to judicial deliberations, reasoning and drafting judgments. To meet this objective, INCRICO aims to tackle the topic using a unique interdisciplinary approach, employing doctrinal legal analysis as well as contemporary sociology of law for explaining international criminal law and international criminal courts and their link to global society. The project’s specific objectives are to: (1) gather, analyse and collate international legal data and sources relevant for determining the content, scope, nature and practice of the ICC’s judicial function, as well as the relevant body of the ICC’s case law/jurisprudence/applicable law, including dissenting and individual/separate opinions; (2) gather (through in-depth interviews with the ICC's judges) and analyse qualitative data on the judges’ perceptions and understanding of their judicial function, in terms of what and how the judges really think, and what they are doing and why, so as to identify the judges’ view and experience at the ICC and how this correlated to the case law of the Court; (3) integrate legal assessment of dissents/case law/jurisprudence of the ICC with the judges’ accounts to map out and critically analyse the ICC’s judicial function; (4) increase awareness and knowledge of the ICC’s judicial function among relevant scientific and criminal justice management/policy making communities, and the general public. INCRICO is involving an excellent academic and interdisciplinary environment at iCourts where the researcher will spend the entire period. This is a unique proposal which targets growing concerns on legitimacy, effectiveness, independence and fairness of global criminal judiciary. Thus, it fits perfectly with the goals of the IF and Horizon 2020.";212194,8;212194,8;H2020-MSCA-IF-2016;/MSCA-IF-EF-CAR;KOBENHAVNS UNIVERSITET;DK;;;;1;0;0;2;0;0 209196;745396;DogSPEC;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Multimodal Spectral Imaging for Canine Skin Erythema Estimation: from the Lab to the Clinic – DogSPEC;2017-08-22;2019-08-21;;"In this action, we propose a novel portable and cost-effective multispectral device for smartphones that will monitor dog skin health in terms of erythema. Up to 50-% of European households own a dog, and the five of the ten most common reasons for a veterinary visit can be reflected in erythematous skin. Currently, there are no methods for the objective estimation of the intensity of erythema. In this action, we will first develop multispectral near-infrared device for the detection of extra absorption peaks of hemoglobin. In order to learn about hemodynamics, we will continue with objective measurements of capillary refill time. Then, we will develop a device for the multimodal acquisition of visible multispectral and fluorescence images and near-infrared multispectral data. This will serve for an estimation of erythema intensity by calculating an erythema index. The latter will be validated using existing dermatological tests (e.g. CADESI) in order to study whether erythema index can replace erythema visual assessment. Finally, we will investigate if there is any correlation between erythema and underlying causes (tumors). The proposed methods can simplify and improve current diagnostic procedures in veterinary dermatology. The action will improve the experienced researcher’s knowledge and skills in both fields of his profession: biophotonics and veterinary medicine, which will lead to well integrated interdisciplinary knowledge. This will allow the researcher to address interdisciplinary research challenges much better and, consequently, enhance his future career prospects. Furthermore, he will also obtain additional training to acquire extra professional skills (e.g. mentorship). Moreover, the beneficiary’s biophotonic techniques will be upgraded and promoted in the new scientific field (i.e. veterinary medicine). Additionally, the host will be able to better validate his work with higher number of samples, which will make research in human medicine much safer.";145904,4;145904,4;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;LATVIJAS UNIVERSITATE;LV;;;;1;0;0;2;0;0 209576;748114;EaRL;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Expert Rule? Judges, Lawyers, and the Practices of Interpretation in International Criminal Law;2018-09-01;2020-08-31;;Since the end of the Cold War, the number of international courts has increased significantly, indicating a growing judicialisation of global governance. At the same time, international judges have begun to change and potentially even create law through their decisions. In international criminal law, a particularly drastic example, international judges repeatedly described the development of international criminal law as one of their main achievements. But have these courts, 15 years after the Rome Statute of the International Criminal Court entered into force, been able to deliver on their objective? How far do judicial interpretations matter in global governance more broadly? Applying an innovative interdisciplinary approach that draws on legal theory, this project (EaRL) capitalises on the recent “practice turn” in International Relations theory to develop a novel theoretical and empirical account of interpretive judicial authority in global governance. EaRL is based on a systematic analysis of all 240 available judgements of international criminal and hybrid courts, including the International Criminal Court, the ad hoc Tribunals for the former Yugoslavia (ICTY) and Rwanda (ICTR), and the Special Court for Sierra Leone (SCSL). In addition, it uses over 40 in-depth expert interviews with international judges, staff at civil society organisations, and government representatives. Ideally located at iCourts, the University of Copenhagen’s globally leading Centre of Excellence for International Courts, EaRL will enable the experienced researcher to complete her interdisciplinary training and to make a timely contribution to the Centre’s impressive body of knowledge on international courts. In addition to its academic impact, EaRL ultimately aims to enhance the judgement-writing process at international criminal courts and to improve the general public’s understanding of international criminal justice.;200194,8;200194,8;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;KOBENHAVNS UNIVERSITET;DK;;;;1;0;0;2;0;0 208968;749154;SURGE;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Social Sustainability and Urban Regeneration Governance: An International Perspective;2017-09-01;2020-08-31;;"The aim of the research is to support the career development of an experienced researcher through an interdisciplinary project that tackles a crucial policy issue for cities globally, that of urban regeneration governance. Developing a novel interdisciplinary conceptual framework, and applying a stakeholder evaluative frame in the analysis, the project explores the governance of urban regeneration projects in two world cities, Vancouver and London. The scientific objectives of the research are: to develop an innovative theoretical framework that integrates different disciplinary perspectives on urban governance; to critically analyse the dynamics of urban regeneration governance and in particular the role of different stakeholders in the process; and to provide research and policy recommendations for dissemination to wide audiences. The outgoing host is the University of British Colombia, Vancouver, at the School of Community and Regional Planning (SCARP), while the return phase will be hosted at Oxford Brookes University (OBU). Both SCARP and OBU provide ideal hosts for the fellow, offering a strong multidisciplinary environment, a network of international contacts, and an outstanding track record of training researchers. The research training objectives of the proposal are to train the fellow in a new methodology, digital ethnography, which she will then apply to the research; to complement the researcher’s knowledge of urban governance in the UK with in-depth understanding of the Canadian case, and so develop a comparative urbanism perspective; to participate in seminars and other events organised by the outgoing and return hosts; and to interact and collaborate with international scholars from different disciplines in areas of mutual interest. In order to maximise the impact of the research, the fellow will also undertake a three-month secondment at a Paris-based NGO, European Alternatives, where her findings will be exploited in real life regeneration settings.";255349,8;255349,8;H2020-MSCA-IF-2016;/MSCA-IF-GF;OXFORD BROOKES UNIVERSITY;UK;;;;1;0;0;2;0;0 209000;750379;SYMBODIN;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;The Symbolism of the Body in Northern Europe. Cognitive Metaphors and Old Norse Myth from the Viking Age to Late Medieval Times;2018-08-01;2020-07-31;;The aim of the proposed research is to investigate the integrative function of bodily metaphors within the Old Norse Literature and Culture. The research will span the culturally important transition from pre-Christian culture to the products of Christian literacy. Its starting point will be the mythic narratives connected with initiation and sacrifice, which have a foremost position in the pre-Christian religion and which are especially rich in the cognitive metaphors of the human body. These myths and rituals exerted an influence as a pattern or model for the whole society, and provide thus an excellent tool for the understanding of its symbolic system and values. In the next step of the project the transition towards Christianity will be explored and assessed, especially its reevaluation of cognitive metaphors of the body, with the aim to map the transformations of symbolism on the borders of two cultural and religious systems. This endeavour will provide a completely new theory shedding new light on the production of meaning in culture and its reinterpretations. The research itself is to be naturally interdisciplinary, integrating religious studies, philology, cognitive linguistics, anthropology and folkloristics. My previous research prepared me for this task to a certain degree, but knowledge exchange is needed to bring it to a completion, especially consultations with scholars and experts in the field of Old Norse Studies. All this can be achieved by a 18 months research internship at the University in Bergen, which provides the best academic conditions for this project, supervised by prof. Jens Eike Schnall, and by a 6 month secondment in Reykjavík, at the University of Iceland and at the Árni Magnússon Institute for Icelandic Studies. This project will apply innovative interdisciplinary approach to the topic and initiate a collaboration between Prague and Bergen and Prague and Reykjavík researchers in Old Norse religion.;196400,4;196400,4;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;UNIVERSITETET I BERGEN;NO;;;;1;0;0;2;0;0 208732;753304;SIFINS;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Stable isotope signatures in dorsal fin spines as a non-invasive and non-lethal alternative to otoliths for reconstructing fish life and environmental history;2017-07-03;2019-09-29;;'The use of stable isotopes as powerful 'natural tags' for reconstructing fishes’ environmental and life history, has been largely restricted to ear bones or otoliths. The extraction of otoliths requires sacrificing the fish, which is not allowed for endangered species, and greatly affects the appearance of a fish, which is non-practical for commercially valuable species as it can diminish their market value. The aim of the SIFINS project is to investigate tuna dorsal fin spines as a non-invasive and non-lethal alternative to otoliths for reconstructing environmental and life histories of individual fishes. Using SI signatures in fin spines of key highly migratory temperate and tropical tunas, SIFINS proposes a novel multispecies and interdisciplinary approach integrating the fields of chronology, chemistry and population dynamics research. SIFINS will provide (i) a more refined understanding of the movement and population-stock structure of tunas across their distribution range and (ii) a new and original perspective of stable isotope chemistry research in fishes, particularly relevant to support the management of endangered and commercially valuable species under the EU Biodiversity and Fisheries policies priorities. The results of the project will promote EU excellence in marine fish population dynamics, likely to be of increasing interest in the future due to climate and human-induced change to marine environments. The applicant’s research and professional skills complement the host infrastructure and research team expertise, and their capacity to manage fellowships/grants and train researchers for the successful outcome of all aspects of the project including training, dissemination of results, and outreach activities. SIFINS will contribute to the researcher’s professional career development putting the fellow in an optimal position to become a leading European scientist in this interdisciplinary research field after a maternity leave career break.';170121,6;170121,6;H2020-MSCA-IF-2016;/MSCA-IF-EF-CAR;FUNDACION AZTI - AZTI FUNDAZIOA;ES;;;;1;0;0;2;0;0 208325;741303;TSH;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;The Spirited Horse: Human-equid relations in the Bronze Age Near East;2017-10-01;2019-09-30;;"This project investigates human-animal relations in the ancient Near East, with equids (horses, donkeys and horse-donkey hybrids) as the main focus, and with an understanding of animals as social actors. The data used includes the material culture of the Bronze Age Near East in the form of archaeological contexts with equid remains (burials, sacred space, settlements and other contexts), supplemented by iconography, textual references and finds associated with equids, such as chariots and harnesses. The application of research from the interdisciplinary field of Human-Animal Studies enables a dynamic approach to human-animal interfaces where the agency of animals is recognised. This results in a new type of study of how humans encounter and interact with other animals, and how those animals in turn interacts with humans, with broader implications for human involvement with their environment, both today and in the past. During the EF, the ER will receive training in archaeozoology, Akkadian and GIS techniques, along with methodological and practical skills that will enable the completion of the project and improve future career prospects. The project's interdisciplinary nature is expressed not only in its theoretical application, but also through engagement with modern equine venues, including veterinary clinics, sports centres, and therapeutic centres (with horses and donkeys either being treated or supporting in the treatment of humans). Dissemination and public engagement will occur in a wide range of areas, including academic papers and conference presentations, podcasts, a project website and social media pages, and participation in public events in Cambridge and abroad.";183454,8;183454,8;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;UK;;;;1;0;0;2;0;0 208193;745865;FIBRANET;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Fibres in Ancient European Textiles;2017-10-01;2019-09-30;;"FIBRANET will shed light to questions on the types of fibres used in ancient Europe, provide data to enhance future identification studies, and open up new paths of possibilities when considering probable answers to fibre identification inquiries. It will bring together conservation, science and archaeology to provide a new interdisciplinary methodology and new interdisciplinary evidence. My objectives are: 1 To produce new knowledge and get training. 2 To answer the research questions: What types of fibres were used in ancient Europe? How should fibre samples be collected? How can fibre deterioration be assimilated? What is the most appropriate analytical methodology? Test the hypotheses: Even similar fibres can be differentiated; Different deterioration mechanisms affect different fibres in specific ways. 3 To ensure sustainability of my results. In collaboration with CTR philologists I will identify fibre references in ancient texts. I will compile data and samples from plants and animals, measure and document fibre properties and morphology as extracted and processed. A unique feature is that the fibres will be treated to assimilate deterioration. Most important, I will create Fibranet, an online database, to make my results available to conservators, archaeologists, biologists, forensic scientists, artists, craftspeople. Fibre identification is the key element in ancient textile studies but surprisingly enough, insufficiently explored. Prolific work has been done in the past, often with inconclusive results mainly due to the rarity and poor condition of the finds, and the immense variety of fibres used locally since antiquity. As a textile conservator trained to detect and understand fibre degradation, I can carry out this highly specialised task. For the analyses, I will use optical and Scanning Electron microscopies, so that my methodology is reproducible. The demand to address these issues is compelling and my project is the only means to achieve that.";212194,8;212194,8;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;KOBENHAVNS UNIVERSITET;DK;;;;1;0;0;2;0;0 205927;716181;HOM;SIGNED;H2020-EU.1.1.;ERC-2016-STG;H2020;Homo Mimeticus: Theory and Criticism;2016-11-01;2021-10-31;;"Mimesis is one of the most influential concepts in Western thought. Originally invoked to define humans as the “most imitative” creatures in classical antiquity, mimesis (imitation) has recently been at the centre of theoretical debates in the humanities, social sciences, and the neurosciences concerning the role of “mimicry,” “identification,” “contagion,” and “mirror neurons” in the formation of subjectivity. And yet, despite the growing confirmations that imitation is constitutive of human behaviour, mimesis still tends to be confined to the sphere of realistic representation. The HOM project combines approaches that are usually split in different areas of disciplinary specialization to provide a correction to this tendency. Conceived as a trilogy situated at the crossroads between literary criticism, cinema studies, and critical theory, HOM’s outcomes will result in two monographs and accompanying articles that explore the aesthetic, affective, and conceptual implications of the mimetic faculty. The first, radically reframes a major proponent of anti-mimetic aesthetics in modern literature, Oscar Wilde, by looking back to the classical foundations of theatrical mimesis that inform his corpus; the second considers the material effects of virtual simulation by looking ahead to new digital media via contemporary science-fiction films; and the third establishes an interdisciplinary dialogue between philosophical accounts of mimesis and recent discoveries in the neurosciences. Together, these new perspectives on homo mimeticus reconsider the aesthetic foundations of a major literary author, open up a new line of inquiry in film studies, and steer philosophical debates on mimesis in new interdisciplinary directions.";1044000;1044000;ERC-2016-STG;/ERC-STG;KATHOLIEKE UNIVERSITEIT LEUVEN;BE;UNIVERSITAET BERN;CH;;1;0;0;2;0;0 212044;741095;PASSIM;SIGNED;H2020-EU.1.1.;ERC-2016-ADG;H2020;Patents as Scientific Information, 1895-2020;2017-10-01;2022-09-30;;“History will remember Barack Obama as the great Slayer of Patent Trolls.” The headline from the 2014 March 20 issue of Wired credits POTUS with, perhaps, an unexpected feat. Referring to companies in the sole business of enforcing patents beyond their actual value, trolls are a recent installment in the history of an intellectual property whose ubiquitousness the Latin word PASSIM (“here and there, everywhere”) neatly captures. In the eye of the storm stands the patent bargain: disclosure of information in return for a limited monopoly. This contractual moment makes patents a source of information, the basis of new innovation. Or does it? By posing this simple question, PASSIM’s bold take on the legitimacy of intellectual property in the governance of informational resources follow patents as legal and informational documents during three historical “patent phases,” producing a visionary and theoretically savvy interpretation of intellectual property that stems from its humanities-based and interdisciplinary project design. PASSIM shows a way out of current analytical gridlocks that earmark the understanding of the role of intellectual property in knowledge infrastructures—most notably the enclosure/openness dichotomy—and provides a fresh take on the complexity of informational processes. A key steppingstone in the PI’s career, her own contribution to PASSIM will be a work of synthesis, highlighting major tendencies in the history of patents as scientific information from 1895 to the present. Four complementary empirical studies target specific themes that strengthen PASSIM’s validity and impact: questions of copyrights in patents, scientists’ patenting strategies both historically and today, the relationship between bibliometrics and patentometrics, and the status of the patent as a legal and informational document. Outputs include workshops, articles, monographs, policy papers and documentation of the project’s experiences with interdisciplinary self-reflexivity.;2261522,73;2261522,73;ERC-2016-ADG;/ERC-ADG;LINKOPINGS UNIVERSITET;SE;UNIVERSITY OF KENT;UK;;1;0;0;2;0;0 197125;665136;OBSERVE;SIGNED;H2020-EU.1.2.1.;FETOPEN-2-2014;H2020;Observing Emergence;2015-06-01;2017-05-31;;"In line with the mission of the FET programme the overarching aim of OBSERVE is to support Europe to grasp leadership early on in new and emerging technology areas that promise to renew the basis for European competitiveness and growth and that will make a difference for society in the decades to come. For this purpose OBSERVE addresses the concrete objective of identifying new opportunities and directions for interdisciplinary research towards new and visionary technology of any kind. More specifically OBSERVE will: • Implement a bottom-up Horizon Scanning process using four different and complementary screening methods that will yield a set of emerging topics. • Combine this process with a broadly based participatory multi-stakeholder dialogue in a tailored sequence of face to face anticipatory dialogues which will result in a list of candidates for “Hotspots” i.e. potential topics for “new opportunities and directions for interdisciplinary research towards new and visionary technology of any kind” thus ensuring exploration of radically new avenues on the one hand and sensitivity to society’s needs on the other. • Provide a 360 degree view on both hard and soft aspects embracing all technology areas in line with the new mission of FET for H2020 with providing a clear set of novel “Hotspots” per observation phase. • Establish a rolling process that can be extended throughout H2020 or further by carefully documenting the methodology, lessons learned and concluding recommendations. • Harness the wealth of information incorporated in the FET project portfolio and community as one pillar of the scanning process thereby providing an structured overview of the FET portfolio. • Ensure a maximum of uptake of both the “Hotspots” identified and the observatory methodology, to strengthen futures literacy, responsiveness and resilience for diverse actors across Europe";410093,75;410093,75;H2020-FETOPEN-2014-CSA;/CSA;FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.;DE;;;;1;0;0;2;0;0 195520;657876;ABRUPT;TERMINATED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Quantifying Abrupt Biotic Responses to Palaeoclimate Change;2016-04-11;2018-04-10;;"Climate change in the 21st century is predicted to push ecosystems across ecological thresholds, potentially resulting in abrupt ecosystem change into new and irreversible states. Ecological theory proposes that non-linear biotic responses are the result of a complex interplay of feedbacks, thresholds and interactions that operate over decades to thousands of years. As a result, standard ecological research methods are generally unable to quantify key ecological dynamics that are relevant for forecasting abrupt ecological change and there is a critical need to integrate long-term ecological data with process-based models. This will result in improved forecasting of climate-change impacts on ecosystems at both local- to global-scales. Such studies will play a critical role in understanding the ‘intrinsic’ factors (e.g. climate-vegetation feedbacks) that can result in non-linear biotic responses to climate change. Sediments are natural data-loggers that preserve the remains of plants and animals over thousands of years. They provide a unique resource for answering current high priority questions related to predicting future ecosystem change because they are the only way to obtain empirical information relevant for understanding long-term ecological dynamics and functioning. In this project I will develop an interdisciplinary framework that integrates state-of-the-art process-based modelling with new high-quality palaeoecological information to quantify the factors that result in non-linear responses to climate change. I will apply the framework to a major vegetation transition in the past: the sclerophyll-rainforest transition in north-east Australia that occurred between 10 and 7 thousand years ago. I will develop this case study for proof-of-concept of a new interdisciplinary framework. This will result in a greater understanding of non-linear biotic responses to climate change.";159460,8;159460,8;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;SENCKENBERG GESELLSCHAFT FUR NATURFORSCHUNG;DE;;;;1;0;0;2;0;0 212642;750447;GEMS;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;The World of the Gáidhealtachd and the origins of the Early Modern British State, 1513-1594.;2018-10-01;2020-09-30;;By 1603 the political power of the Gaelic world, or Gáidhealtachd, had been broken in the face of the recently created British state. Though certain Gaelic dynasties (i.e., the Campbells and O’Briens) actively worked with the state, little research has been undertaken on how dynasties such as the O’Donnells and O’Neills possessed the capacity not only to resist but also to threaten this process of state formation throughout the 16th century. Using a series of case studies and drawing upon a broad base of primary material, this project explores the political and military development of the Gáidhealtachd during two key phases of Anglo-Scottish relations. The first section investigates how certain Gaelic lords manipulated the course of Anglo-Scottish hostilities from 1513-59 in order to enhance their position within ‘British’ politics. The second section explores how the Gaelic lords reacted to the development of Anglo-Scottish peace and amity from 1560-94. The main objective of this project is therefore to uncover the basis for the strong level of Gaelic political and military resilience within ‘British’ politics throughout the 16th century and how significant a factor this was in contributing to the outbreak of the Nine Years War (1594-1603). This is an interdisciplinary project, involving Gaelic, English, Scottish, and Latin historical material as well as elements of literature and archaeology. The project will be strengthened by the experienced interdisciplinary research team at the University of Glasgow and will involve both the transfer of knowledge to the host institution and the training of the researcher in new competences. Ultimately, this project will make a major intervention in the history of Early Modern Ireland and Britain and will result in a series of high-impact publications. The proposal also entails a secondment to BBC Scotland and a detailed public engagement strategy aimed at changing public perceptions of 16th century Ireland and Britain.;183454,8;183454,8;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;UNIVERSITY OF GLASGOW;UK;;;;1;0;0;2;0;0 205176;678889;CLIMASLOW;SIGNED;H2020-EU.1.1.;ERC-StG-2015;H2020;Slowing Down Climate Change: Combining Climate Law and Climate Science to Identify the Best Options to Reduce Emissions of Short-Lived Climate Forcers in Developing Countries;2017-01-01;2021-12-31;;"The ClimaSlow project opens new interdisciplinary horizons to identify the best opportunities to enhance the global legal and regulatory framework for reducing emissions of short-lived climate pollutants (SLCFs), with particular attention to developing countries as projected key sources of future SLCF emissions. It proceeds from the assumption that strengthening the global legal and regulatory framework for SLCFs would bring important benefits in terms of slowing down climate change and reducing local air pollution. However, legal and regulatory options to step up action on SLCFs have not been studied comprehensively. Furthermore, the climate impacts of the various options are not adequately understood. In contrast to traditional legal analysis that would focus one legal system or instrument, the project will study the relevant legal and regulatory frameworks comprehensively, considering the international, regional, national and transnational levels. It will seek to identify various options, both formal legal instruments and informal regulatory initiatives, to strengthen the global legal and regulatory frameworks applicable to SLCFs. In addition to providing information on best options to regulate SLCFs, this novel, comprehensive approach will help scholars to improve their understanding of the implications of ongoing changes in global legal landscape, including its presumed fragmentation and deformalisation. Addressing an important gap in current knowledge, the project will combine analysis of the merits of the various legal and regulatory options with estimates of their climate change impacts on the basis of climate modeling. This way, it will be able to identify the alternatives that are the most promising both from the legal point of view and in terms of climate change mitigation potential. The project will generate information that is policy-relevant and context-specific but can simultaneously provide broader lessons and open new interdisciplinary horizons.";1456179;1456179;ERC-2015-STG;/ERC-STG;ITA-SUOMEN YLIOPISTO;FI;;;;1;0;0;2;0;0 200954;701557;TEXREX;CLOSED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;TEXTILE REFLECTIONS: MULTI-SENSORY REPRESENTATION OF TEXTILE WORK IN LATIN POETRY AND PROSE;2016-09-01;2018-08-31;;This interdisciplinary research project explores and re-interprets the representations of textile work and textiles in Latin literature. Literary analysis taking into account matters of metrics, sound figures and structure will show that Latin authors display greater technical understanding of textile work than previously assumed, and suggest that their tacit knowledge of textiles/textile production has influenced the artistic development of descriptions of textile crafts. By indexing and analysing all references to textile work in Latin sources (as called for by J.P. Wild in 2000), I will address the discipline-wide problem of multi-purpose terminology. Interdisciplinarity is fundamental to my project and a core value of my host institution (Centre for Textile Research): observation and recordings of reconstruction of ancient textile work (experimental archaeology) will be the basis for my investigation of semblances of textile work in metre, sound-play and structure in Latin texts, providing thematic literary interpretation, highlighting neglected connections between structure, sound-play and meaning. The project results will complement knowledge based on epigraphy and archaeology of the role played by textiles and textile production in Roman life, their ideological connotations, and trials investigation of ancient soundscapes through literary sources. My project relates to four disciplines: philology, sound studies, ancient history, and archaeology. An ambitious training programme is planned for me to expand my expertise in Classical Philology to include aspects of textile archaeology and ancient history, an outcome of this will be a distance learning course, also involving me providing training in online learning at CTR. To maximise long-term impact, I will receive training in research management and network building, e.g. through planned conference organisation and co-publication of a paper with my supervisor Prof. Nosch, part of a wider dissemination strategy.;212194,8;212194,8;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;KOBENHAVNS UNIVERSITET;DK;;;;1;0;0;2;0;0 212282;754496;FELLINI;SIGNED;H2020-EU.1.3.4.;MSCA-COFUND-2016;H2020;FELLowship for Innovation at INFN;2018-01-01;2022-12-31;;"The FELLINI fellowship programme is a new, high-quality fellowship scheme based on a modern research and training approach, which aims at research excellence and promoting researcher mobility and training. FELLINI combine best practice found across the EU with a number of innovative elements that shall provide all Fellows with an ideal basis for their future careers, preparing them for a wide range of career options. The 'Istituto Nazionale di Fisica Nucleare' (INFN), the Italian public research performing organization dedicated to the study of the fundamental constituents of matter and their interactions and to the development of the cutting-edge technologies needed to achieve these scientific goals. Within FELLINI, INFN plans to improve the 'standard fellowship programme' for incoming post-doctoral fellows. Fellows can choose freely among a very large number of disciplines (Particle Physics, Astroparticles, Nuclear Physics, Theoretical Physics, Applied and Interdisciplinary Physics, Instrumentation and Advanced Technologies) and topics, where the Institute has a tradition of excellence. FELLINI will support 30 Fellows through a three-year appointments rather than the standard two-year terms of INFN, with a full employment contract. In order to give a burst to the career of young researchers, the opportunity of a yearly secondment to an international laboratory or in the private sector, on paid leave from INFN under the conditions of the full employment contract, will be provided. Moreover, Fellows will broaden their skills using the numerous training opportunities offered by the programma and through their high exposure to an interdisciplinary, international and intersectoral environment.";6372000;3186000;H2020-MSCA-COFUND-2016;/MSCA-COFUND-FP;ISTITUTO NAZIONALE DI FISICA NUCLEARE;IT;;;;1;0;0;2;0;0 222138;839553;STOICISM;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Stochastic Communication Inside Cortical Microcolumns;2019-09-01;2021-08-31;;"Neurodegeneration, such as Alzheimer’s disease, currently affects 15 million people in the US with a death rate of 29.5% among 65\ years old and produces a cost around 200 billion dollars per annum. These type of pathologies are caused by neuronal communication failures in multi-scales of the cortical microcolumns. Neuroscience has historically provided theories and experiments to explain the signal propagation and neurodegeneration inside cortical microcolumns, but these behaviours are far from being fully explained. The newly formed research area of molecular communications can bring light to this challenge by using information and communication theory in this scenario. A novel interdisciplinary methodology (multi-scale modelling \ neurological modelling \ information theory) can analyze and quantify the dynamics in the synaptic plasticity and provide further understanding about cortical microcolumns. With this approach, STOICISM project aims to i) model the multi-scale cortical microcolumn neurology; ii) model and quantify the neuronal communication; iii) investigate the long-term plasticity dynamics and control strategies. STOICISM will develop a complete in-silico model of the 2mm cortical microcolumn that will account for its multi-scale communication. The synaptic plasticity variation will be modelled as a stochastic model based on in-vitro experimentation of the neuron-astrocyte communication. This action requires the researcher to move to a world-center in computational biophysics, such as BioMediTech, where he can get appropriate training, perform biological experiments and collaborate with other top researchers while being supervised by the renowned leading academic Prof. Jari Hyttinen. STOICISM will change the way we understand the effects of neurodegeneration which will enable future non-invasive detection and drug discovery, potentially creating a longer-term impact on the ageing society.";202680,96;202680,96;H2020-MSCA-IF-2018;/MSCA-IF-EF-ST;TAMPEREEN KORKEAKOULUSAATIO SR;FI;;;;1;0;0;1;0;0 222179;840262;EpimiRTherapy;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Using human tissue to translate microRNA-based therapies for epilepsy;2019-12-01;2021-11-30;;The overall research aim of EpimiRTherapy is to elucidate the mechanism of a novel disease-modifying therapy for epilepsy at single cell resolution in the human brain. MicroRNAs are short non-coding RNAs which regulate protein levels in the brain. Certain microRNAs are strongly associated with epilepsy and their knockdown, using antisense molecules called ‘antagomirs’, has anti-seizure effects in rodents. Antagomir targeting microRNA-134 (ant-134) is a particularly promising disease-modifying treatment for epilepsy, which could meet an urgent clinical need. However, antagomirs to treat neurological disease have never been tested in humans due to limited translational evidence. EpimiRTherapy, for the first time, fills this gap: I will use state-of-the-art techniques to produce human brain slices from tissue surgically resected during temporal lobectomies for epilepsy. I will use a combination of molecular techniques (acquired at the host lab in RCSI and through secondment to ICL) and electrophysiology, my core expertise, to determine the impact of ant-134 on the biophysical and transcriptional landscapes of human tissue and a network and single neuron level. This will be complemented with cutting edge systems modelling and imaging techniques acquired through collaborations. This fellowship, through advanced interdisciplinary and intersectoral training, will serve as a launchpad for reaching a position of professional independence and maturity, whilst at the same time facilitating a transfer of knowledge between myself, the host and the collaborators, by bringing cutting edge electrophysiology and human tissue processing techniques to RCSI and addressing an urgent and unmet clinical need for novel epilepsy treatments.;184590,72;184590,72;H2020-MSCA-IF-2018;/MSCA-IF-EF-ST;ROYAL COLLEGE OF SURGEONS IN IRELAND;IE;;;;1;0;0;1;0;0 222181;840414;MutANTs;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Mutation rate evolution in attine ants;2020-04-01;2022-03-31;;"Germline mutation rate (GMR) is a key concept in all disciplines of biology, and particularly in evolutionary biology and the biomedical sciences. GMR varies both across and within species, but what drives this variation is unclear. Theories predict that GMR variation is shaped by environmental selection pressures, by effective population sizes, and by prevailing life-history traits (across species) and parental age at reproduction (within species). However, our understanding is extremely limited because within-species GMR variation has been investigated only to some extent in humans, and larger comparative genome-level datasets in other clades have not yet been pursued. I propose to start filling this gap by studying GMR in attine fungus-growing ants and a set of outgroup. non-attine ants. The attine ants, a ca. 55 MY old monophyletic lineage, are ideal for understanding GMR variation across and within species because their basic ecology is similar (obligate dependence of farmed fungi for food) but their life-histories diversified enormously from the base to the crown of their phylogenetic tree, which presently has 15 recognized genus-level branches and >230 species. Against a background dataset of ~20 high quality genomes, I propose to obtain genome-wide GMR estimates for 12 attine ants and 7 non-attine ants while controlling for confounders of phylogeny, colony size, life-span and effective population size. In addition, I will do an in-depth analysis of a single leafcutter ant species with long-lived queens and stored sperm of the same age, where I can also control for parental age. I will implement the MutANTs project at the Centre for Social Evolution in Copenhagen, an internationally renowned research hub for interdisciplinary omics research on ants, with Professors Guojie Zhang and Jacobus Jan Boomsma as joint hosts. I expect that in the two years available MutANTs will yield the first comparative data to predict GMRs across and within species.";219312;219312;H2020-MSCA-IF-2018;/MSCA-IF-EF-ST;KOBENHAVNS UNIVERSITET;DK;;;;1;0;0;1;0;0 222180;840302;MEMORIGHTS;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Cultural Memory in LGBT Activism for Rights;2019-09-01;2022-08-31;;"MEMORIGHTS investigates the uses of cultural memory in LGBT activism for rights from a memory studies perspective. Organising commemorations and exposing past LGBT rights violations, LGBT memory practices spread globally through local adaptations, impacting on public agendas. Yet, research on how cultural memory is used in activism is underdeveloped in the memory studies field, particularly with regard to the LGBT case. MEMORIGHTS addresses this knowledge gap joining a growing scholarship on the nexus memory-activism, innovatively bridging European and Latin American perspectives in the field. Taking a transnational perspective, the project analyses how commemorations, archive collections and memorial spaces are used in LGBT activism between Latin America, focusing on Argentina, and Europe, with case-studies on the Netherlands and Italy. The applicant will tailor an advanced methodological toolbox that includes semiotic discourse analysis, netnography and ethnography. The project will promote an innovative theoretical shift in focus in memory studies, towards the analysis of bottom-up transnational dynamics and beyond the traumatic model, which is dominant in the field. Studying the nexus memory-LGBT activism will allow for applications to other forms of activism and civic engagement, which may empower local actors, invigorate civil society and maximise the impact of rights dialogues in a moment of political uncertainties and growing inequalities in the EU. The outputs include three articles; an edited book; policy guidelines; a workshop for activists and professionals; two academic workshops; an international symposium. Research and training activities at the University of Utrecht, the University of Buenos Aires and the International Institute of Social History will directly benefit the applicant’s career prospects, equipping him with new skills and knowledge, and placing him at the forefront of the field as an interdisciplinary researcher.";213816,96;213816,96;H2020-MSCA-IF-2018;/MSCA-IF-GF;UNIVERSITEIT UTRECHT;NL;;;;1;0;0;1;0;0 200088;690991;PEARL;SIGNED;H2020-EU.1.3.3.;MSCA-RISE-2015;H2020;Periodically bent crystals for crystalline undulators;2016-01-01;2019-12-31;;The PEARL project aims at advancing the technologies for manufacturing of high quality Periodically Bent Crystals (PBCr). The PBCr developed in the course of this project will be utilised for the construction of novel light sources of high-energy (h??102 keV up to GeV range) monochromatic electromagnetic radiation by means of a Crystalline Undulator (CU) [1]. The technological and experimental part of this project will be accompanied by the complimentary advanced theoretical research utilising modern theoretical, computational and modelling methods accomplished with high performance computing techniques. A broad interdisciplinary, international collaboration has been created in the frame of FP7 PIRSES-CUTE project, which was focused on initial experimental tests of the CU idea and the related theory, for review see [1]. This project has been successfully completed in March 2015 and left the matter experimentally validated to a degree that is tantalising, requiring further experimentation. In particular CUTE elucidated the demand on manufacturing PBCrs of an exceptional lattice quality, their experimental characterisation and exposure against the high quality beams of ultra-relativistic electrons and positrons for the observation of the strong coherent effects in the photon emission process. PEARL will focus on solving the whole complex of the important technological, experimental and theoretical problems aiming to achieve the major breakthrough in this important research area. The PEARL international collaboration is extended with respect to CUTE and involves the new partners with the essential, necessary, complementary expertise and experimental facilities. The PEARL research programme is highly collaborative and requiring numerous exchange visits between the involved laboratories, joint workshops and conferences. Therefore, RISE type of project is the most suitable for strengthening of this very essential, ongoing, international collaborative research.;720000;693000;H2020-MSCA-RISE-2015;/MSCA-RISE;MBN RESEARCH CENTER GGMBH;DE;"AARHUS UNIVERSITET;JOHANNES GUTENBERG-UNIVERSITAT MAINZ;EUROPEAN SYNCHROTRON RADIATION FACILITY;UNIVERSITE PAUL SABATIER TOULOUSE III;THE OPEN UNIVERSITY;UNIVERSITA DEGLI STUDI DI FERRARA;ISTITUTO NAZIONALE DI FISICA NUCLEARE";"DK;DE;FR;UK;IT";;1;0;0;1;0;0 199878;688722;NEXTLEAP;SIGNED;H2020-EU.2.1.1.;ICT-10-2015;H2020;NEXTLEAP;2016-01-01;2018-12-31;;The objective of the NEXTLEAP project is to build the fundamental interdisciplinary internet science necessary to create decentralized, secure, and rights-preserving protocols for the next generation of collective awareness platforms. The long-term goal of NEXTLEAP is to have Europe take the “next leap ahead” of the rest of the world by solving the fundamental challenge of determining how both to scientifically build and how to help citizens and institutions adopt open-source decentralized and privacy-preserving digital social platforms in contrast to proprietary centralized cloud-based services and pervasive surveillance that function at the expense of rights and technological sovereignty.;1968030;1968030;H2020-ICT-2015;/RIA;INSTITUT NATIONAL DE RECHERCHE ENINFORMATIQUE ET AUTOMATIQUE;FR;"MERLINUX GMBH;ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE;INSTITUT DE RECHERCHE ET D'INNOVATION;FUNDACION IMDEA SOFTWARE;UNIVERSITY COLLEGE LONDON;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS";"DE;CH;FR;ES;UK";;1;0;0;1;0;0 199919;690853;assymcurv;SIGNED;H2020-EU.1.3.3.;MSCA-RISE-2015;H2020;The influence of the cell membrane asymmetry and curvature on the functioning of membrane proteins and the transport of therapeutic compounds;2016-01-01;2019-12-31;;"Real cell membranes are essentially asymmetric and non-planar. Outer leaflets of the plasma membranes contain neutral lipids and glycolipids, while the inner leaflets host practically all anionic lipids and phosphoinositides. In addition to asymmetric composition the membranes are usually curved due to spontaneous curvature of the membrane lipids and an influence of membrane proteins and cytoskeleton. There are many cellular phenomena, which are influenced by the asymmetry and the membrane curvature such as formation of synaptic vesicles, blebs and apoptotic bodies, membrane fusion and splitting, budding of enveloped viruses, endo and exocytosis, etc. In this work we propose comprehensive interdisciplinary study of the influence of membrane asymmetry and curvature on the functioning of integral membrane proteins and the transmembrane transport of therapeutic compounds (such as cisplatin and its derivatives). The goal is to reveal major physical factors, which distinguish asymmetric and curved membrane environment and govern interactions, orientation and diffusion of the small molecules (drugs) and large integral proteins. The combination of experimental methods (“wet” biochemistry and molecular biology, enhanced infrared and Raman spectroscopy) and computer simulations (coarse-grained and atomistic molecular dynamics, quantum chemistry) would be used in the project in complimentary manner.";202500;202500;H2020-MSCA-RISE-2015;/MSCA-RISE;INSTITUTE OF PHYSICS OF NATIONAL ACADEMY OF SCIENCE OF UKRAINE;UA;"TARTU ULIKOOL;UNIVERSITE DE FRANCHE-COMTE;LATVIJAS UNIVERSITATES CIETVIELU FIZIKAS INSTITUTS;MATERIALS RESEARCH CENTER";"EE;FR;LV;UA";;1;0;0;1;0;0 199729;667302;CoCA;SIGNED;H2020-EU.3.1.1.;PHC-03-2015;H2020;Comorbid Conditions of Attention deficit / hyperactivity disorder;2016-01-01;2020-12-31;;Understanding mechanisms underlying comorbid disorders poses a challenge for developing precision medicine tools. Psychiatric disorders are highly comorbid, and are among the last areas of medicine, where classification is driven by phenomenology rather than pathophysiology. We will study comorbidity between the most frequent psychiatric conditions, ADHD, mood/anxiety, and substance use disorders, and a highly prevalent somatic disease, obesity. ADHD, a childhood-onset disorder, forms the entry into a lifelong negative trajectory characterized by these comorbidities. Common mechanisms underlying this course are unknown, despite their relevance for early detection, prevention, and treatment. Our interdisciplinary team of experts will integrate epidemiologic/genetic approaches with experimental designs to address those issues. We will determine disease burden of comorbidity, calculate its socioeconomic impact, and reveal risk factors. We will study biological pathways of comorbidity and derive biomarkers, prioritizing two candidate mechanisms (circadian rhythm and dopaminergic neurotransmission), but also leveraging large existing data sets to identify new ones. A pilot clinical trial to study non-pharmacologic, dopamine-based and chronobiological treatments will be performed, employing innovative mHealth to monitor and support patients’ daily life. Integration of findings will lead to prediction algorithms enhancing early diagnosis and prevention of comorbidity. Finally, we will screen to repurpose existing pharmacological compounds. Integrating complementary approaches based on large-scale, existing data and innovative data collection, we maximize value for money in this project, leading to insight into the mechanisms underlying this comorbidity triad with its huge burden for healthcare, economy, and society. This will facilitate early detection and non-invasive, scalable, and low-cost treatment, creating opportunities for substantial and immediate societal impact.;6192770,5;5999020,5;H2020-PHC-2015-two-stage;/RIA;JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN;DE;"AARHUS UNIVERSITET;TARTU ULIKOOL;THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK;STICHTING KATHOLIEKE UNIVERSITEIT;UNIVERSIDAD DE GRANADA;ACADEMISCH ZIEKENHUIS GRONINGEN;KARLSRUHER INSTITUT FUER TECHNOLOGIE;UNIVERSITAT DE BARCELONA;UNIVERSITATSMEDIZIN ROSTOCK;UNIVERSITAETSKLINIKUM HEIDELBERG;KAROLINSKA INSTITUTET;FUNDACIO HOSPITAL UNIVERSITARI VALL D'HEBRON - INSTITUT DE RECERCA;Concentris Research Management GmbH;UNIVERSITETET I BERGEN;HGC GESUNDHEITSCONSULT GMBH;KING'S COLLEGE LONDON";"DK;EE;US;NL;ES;DE;SE;NO;UK";;1;0;0;1;0;0 200402;705652;ODEON;CLOSED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Online DEposition over OceaNs: Modeling the effect of air pollution on ocean bio-geochemistryin an Earth System Model;2016-10-01;2018-09-30;;Iron (Fe) deposition from dust and combustion aerosols is essential for the marine primary productivity in large portions of the world ocean, where phytoplankton growth mitigates part of the anthropogenic CO2 emissions. Under polluted conditions, the atmospheric acidity and organic ligands dramatically enhance aerosol Fe-mobilization, perturbing also the marine CO2 uptake capacity upon aerosol Fe deposition. Air-quality regulations, designed to decrease future atmospheric pollution, will consequently moderate the dissolved Fe deposition flux over oceans and change its pattern. However, the effect of air pollution on the bioavailable Fe supply into the oceans and their primary productivity remains largely ambiguous, with a likely but poorly known climatic impact. The ODEON project will address this long-standing research question by performing for the first time coupled atmosphere-ocean-climate simulations with the European Earth System Model (ESM) EC-Earth, focused on the impacts of Fe deposition on the oceanic carbon-cycle. Recently, important advances were made by the applicant in understanding aerosol Fe dissolution and emission processes. However, ESMs still use simplified parameterizations and asynchronous coupling of Fe supply to the marine biogeochemistry, inserting severe uncertainties in the response of the carbon-cycle to anthropogenic emissions. ODEON aims to improve this situation by developing modelling tools beyond-state-of-the-art, to simulate the atmospheric Fe-cycle in EC-Earth coupled to the embedded ocean biogeochemistry model. The future fellow’s strong atmospheric chemistry modelling background, together with the advanced training-through-research plan on cutting-edge and multi-disciplinary EMS techniques, ensures the feasibility of this project. ODEON’s training scheme in climate modelling, ocean biogeochemistry and interaction with science-users will contribute to the applicant’s development as an independent and interdisciplinary researcher.;177598,8;177598,8;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;UNIVERSITEIT UTRECHT;NL;;;;1;0;0;1;0;0 199761;668863;SyBil-AA;SIGNED;H2020-EU.3.1.1.;PHC-02-2015;H2020;Systems Biology of Alcohol Addiction: Modeling and validating disease state networks in human and animal brains for understanding pathophysiolgy, predicting outcomes and improving therapy;2016-01-01;2019-12-31;;Alcohol addiction ranks among the primary global causes of preventable death and disabilities in human population, but treatment options are very limited. Rational strategies for design and development of novel, evidence based therapies for alcohol addiction are still missing. Within this project, we will utilize a translational approach based on clinical studies and animal experiments to fill this gap. We will provide a novel discovery strategy based on systems biology concepts that uses mathematical and network theoretical models to identify brain sites and functional networks that can be targeted specifically by therapeutic interventions. To build predictive models of the ‘relapse-prone’ state of brain networks we will use magnetic resonance imaging and neurochemical data from patients and laboratory animals. The mathematical models will be rigorously tested through experimental procedures aimed to guide network dynamics towards increased resilience. We expect to identify hubs that promote ‘relapse-proneness’ and to predict how aberrant network states could be normalized. Proof of concept experiments in animal will need to demonstrate this possibility by showing directed remodeling of functional brain networks by targeted interventions prescribed by the theoretical framework. Thus, our translational goal will be achieved by a theoretical and experimental framework for making predictions based on fMRI and mathematical modeling, which is verified in animals, and which can be transferred to humans. To achieve this goal we have assembled an interdisciplinary consortium (eight European countries) of world-class expertise in all complementary skills required for the project. If successful this project will positively impact on the development of new therapies for a disorder with largely unmet clinical needs, and thus help to address a serious and widespread health problem in our societies.;5759923,75;5759923,75;H2020-PHC-2015-two-stage;/RIA;ZENTRALINSTITUT FUER SEELISCHE GESUNDHEIT;DE;"LINKOPINGS UNIVERSITET;METANOMICS HEALTH GMBH;UNIVERSITEIT LEIDEN;HELSINGIN YLIOPISTO;THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;OTTO-VON-GUERICKE-UNIVERSITAET MAGDEBURG;BEN-GURION UNIVERSITY OF THE NEGEV;AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS;THE UNIVERSITY OF SUSSEX;FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;BRAIN RESEARCH AND DEVELOPMENT SERVICES LTD;ASOCIATIA TRANSYLVANIAN INSTITUTE OF NEUROSCIENCE;INSTITUTUL ROMAN DE STIINTA SI TEHNOLOGIE";"SE;DE;NL;FI;UK;IL;ES;IT;RO";;1;0;0;1;0;0 199128;692257;BALTICS;SIGNED;H2020-EU.4.b.;H2020-TWINN-2015;H2020;Building on Advanced Lofar Technology for Innovation, Collaboration, and Sustainability;2016-01-01;2018-12-31;;"Ventspils International Radio Astronomy Center (VIRAC) is the only institute in Latvia engaged in radio astronomy (RA), and indeed the only RA research centre in the Baltic States. ASTRON and UMAN are world-class centres of expertise in RA science since 1950s. They recognize VIRAC as a strategically important partner for their future endeavours, in particular in the further instrumental development and maximal science utilization of their state-of-the-art physically distributed radio telescope facilities: LOFAR, and e-MERLIN. Addressing the specific challenge of the call BALTICS has the primary objective to directly and significantly increase the expertise level of VIRAC staff that will become able to carry out internationally-competing scientific research: • As a result, the number of peer reviewed VIRAC publications on LOFAR-related subjects will increase from 1 to 5 per year. • The number of VIRAC staff members (co-)authoring scientific research papers for top-level journals will increase from 4 to 10. • BALTICS is specifically designed to cement the networking collaborations between ASTRON, UMAN, and VIRAC. • BALTICS is also the perfect stepping stone on the way to future financing, realization, and exploitation of LOFAR station in Latvia joining ITL network. As the essential all-round and in-depth training of VIRAC staff proceeds, the institute will naturally become a long-term collaborator in the interdisciplinary research networks surrounding the ILT. This is a win-win approach, which addresses strategic interests of ASTRON and UMAN, in their quest for further extension and ultimate exploitation of the top-level facilities in which they currently are leaders. BALTICS will achieve the defined objectives by carefully chosen depth and breadth of training where a cross-section of 20 VIRAC staff members will be intensively trained during lectures, practical exercises, staff exchange visits, workshops, summer school, advisory consultations.";999652,5;999652,5;H2020-TWINN-2015;/CSA;VENTSPILS AUGSTSKOLA;LV;"STICHTING ASTRON, NETHERLANDS INSTITUTE FOR RADIO ASTRONOMY;THE UNIVERSITY OF MANCHESTER;STICHTING NEDERLANDSE WETENSCHAPPELIJK ONDERZOEK INSTITUTEN";"NL;UK";;1;0;0;1;0;0 198839;691025;ENCASE;SIGNED;H2020-EU.1.3.3.;MSCA-RISE-2015;H2020;EnhaNcing seCurity And privacy in the Social wEb: a user centered approach for the protection of minors;2016-01-01;2019-12-31;;"ENCASE will leverage the latest advances in usable security and privacy to design and implement a browser-based architecture for the protection of minors from malicious actors in online social networks. The ENCASE user-centric architecture will consist of three distinct services, which can be combined to form an effective protective net against cyberbullying and sexually abusive acts: a) a browser add-on with its corresponding scalable back-end software stack that collects the users’ online actions to unveil incidents of aggressive or distressed behavior; b) a browser add-on with its associated scalable software stack that analyses social web data to detect fraudulent and fake activity and alert the user; and c) a browser add-on that detects when a user is about to share sensitive content (e.g., photos or address information) with an inappropriate audience and warns the user or his parents of the imminent privacy threat. The third add-on has usable controls that enable users to protect their content by suggesting suitable access lists, by watermarking, and by securing the content via cryptography or steganography. The three browser add-ons and the back-end social web data analytics software stack will be assessed with user studies and piloting activities and will be released to the public. The foundation of the research and innovation activities will be a diligently planned inter-sectorial and interdisciplinary secondment program for Experienced and Early Stage Researchers that fosters knowledge exchange. The academic partners will contribute know-how on user experience assessment, large scale data processing, machine learning and data-mining algorithm design, and content confidentiality techniques. The industrial partners will primarily offer expertise in production-grade software development, access to real-world online social network data, and access to numerous end-users through widely deployed products.";2160000;2160000;H2020-MSCA-RISE-2015;/MSCA-RISE;TECHNOLOGIKO PANEPISTIMIO KYPROU;CY;"LSTECH LTD;ARISTOTELIO PANEPISTIMIO THESSALONIKIS;UNIVERSITA DEGLI STUDI ROMA TRE;INNOVEITORS (INNOVATORS) EFARMOGES YPSILIS TECHNOLOGIAS AE;TELEFONICA INVESTIGACION Y DESARROLLO SA;SIGNALGENERIX LIMITED;UNIVERSITY COLLEGE LONDON;CY.R.I.C CYPRUS RESEARCH AND INNOVATION CENTER LTD";"UK;EL;IT;ES;CY";;1;0;0;1;0;0 198597;639403;WORKANDHOME;SIGNED;H2020-EU.1.1.;ERC-StG-2014;H2020;Reshaping society and space: home-based self-employment and businesses;2015-10-01;2020-09-30;;The aim of WORKANDHOME is to develop a new framework for understanding fundamental changes currently taking place to work that situates individuals as economic actors within the context of their wider life domains, household, home and neighbourhood. This will break new ground in how we understand and classify economic activity, the home, the firm, places of economic activity, labour markets and ‘residential’ neighbourhoods. Significant and rising numbers of people work from home as a self-employed worker or business owner throughout Europe. This will be the first study that explores social, economic and spatial aspects of homeworking by self-employed workers and business owners including the role of new technologies and social media in dissolving the home-work boundary. This is an important new area for social science research since home-based self-employment and businesses vividly manifest the interconnection of ‘home’ and ‘work’ and of the ‘economic’ and the ‘social’ as part of an increasingly complex society. WORKANDHOME will integrate theoretical perspectives from economic geography, entrepreneurship and small business research, sociology, economics, housing and neighbourhood studies. In order to investigate new realities of how people work and live, this study will integrate analytical methods across the social sciences and computer sciences and create a new fusion of primary, secondary and ‘big’ social media data from the UK, the Netherlands, Germany, Europe and the world. WORKANDHOME offers a major step forward in understanding how people live, work, do business and shape space. Its integrated and international approach will stimulate considerable interdisciplinary exchange across disciplines in the social sciences for better understanding and tackling contemporary societal and economic changes and challenges.;1430920;1430920;ERC-2014-STG;/ERC-STG;UNIVERSITY OF SOUTHAMPTON;UK;"ILS - INSTITUT FUR LANDES- UND STADTENTWICKLUNGSFORSCHUNG gGMBH;THE UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS;UNIVERSITEIT UTRECHT";"DE;UK;NL";;1;0;0;1;0;0 199758;668724;TECHNOBEAT;SIGNED;H2020-EU.3.1.3.;PHC-16-2015;H2020;Tools and TECHNOlogies for Breakthrough in hEArt Therapies;2016-01-01;2019-12-31;;"Cardiovascular diseases including myocardial infarction (MI), which entails the irreversible loss of heart muscle tissue, constitute a major socio-economic burden in global healthcare. With whole organ transplantation as the only treatment option for end-stage heart failure, MI patients could particularly benefit from advanced cell therapies aimed at the functional reconstitution of damaged hearts. Human induced pluripotent stem cells (hiPSCs) can be derived by reprogramming patients’ somatic cells. In contrast to adult (stem) cells e.g. from blood, bone marrow or the heart, hiPSCs have unlimited expandability and differentiation potential into all relevant cell types including cardiomyocytes, endothelial cells, pericytes and connective tissue-forming cells, making them highly attractive as a universal cell source for organ repair. However, technologies for the robust therapeutic scale production of hiPSC-derived progenies in line with GMP standards and at reasonable cost are currently lacking. TECHNOBEAT’s ultimate objectives are 1) to advance therapeutic scale cell production through innovative bioreactor technologies and novel cell monitoring tools, and 2) to develop regulatory compliant bioprocessing of innovative iPSC-based cardiac µ-tissue. The clinical translation of cardiac µ-tissue will require 3) the development and application of tools for improved cell delivery and longitudinal in vivo monitoring of cell grafts, and 4) proof-of-concept for safety and functional integration in physiologically relevant preclinical models of cellular heart repair. Through its interdisciplinary excellence, TECHNOBEAT’s consortium of leading European stem cell researchers, clinicians, tissue-, bioprocess-, and technical- engineers in industry and academia is ideally positioned to address these ambitious objectives. It will provide new treatment options for suffering patients and increase Europe’s attractiveness as a hub for innovative medical technologies.";5968850;5968850;H2020-PHC-2015-two-stage;/RIA;MEDIZINISCHE HOCHSCHULE HANNOVER;DE;"ACADEMISCH ZIEKENHUIS LEIDEN;KADIMASTEM LTD;THE UNIVERSITY OF SHEFFIELD;UNIVERSITAIR MEDISCH CENTRUM UTRECHT;DASGIP INFORMATION AND PROCESS TECHNOLOGY GMBH;OVIZIO IMAGING SYSTEMS;PARACELSUS MEDIZINISCHE PRIVATUNIVERSITAT SALZBURG - PRIVATSTIFTUNG";"NL;IL;UK;DE;BE;AT";;1;0;0;1;0;0 198440;642861;BioSmartTrainee;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2014-ETN;H2020;Training in Bio-Inspired Design of Smart Adhesive Materials;2015-10-01;2019-09-30;;"The last half century has seen a tremendous advancement in adhesives technology and has led to widespread replacement of mechanical fasteners with adhesive bonds (e.g. aircraft, automobile, construction, etc.). Bonding to wet, rough and fouled surfaces, however, remains challenging and adhesive technology is rarely applied for bonding in wet conditions, such as in (orthopaedic) medicine. Therefore, a need exists to educate young researchers in this interdisciplinary research field of controlling adhesion under wet conditions and to bridge the gap between the fundamentals of underwater adhesives and their practice. BioSmartTrainee is set up to provide such training by a combination of three complementary scientific fields: polymer science, adhesion and (fluid)-biomechanics. We aim to (i) extract principles from biological systems and mimic them to design synthetic materials; to (ii) experimentally test their adhesion properties in wet conditions and to (iii) clarify the adhesion mechanisms based on natural examples and theoretical modelling. These innovative adhesives will be useful for reversible attachment to a variety of surfaces in wet environments and, therefore, be highly relevant for products from European industry such as technological adhesives, coatings, tissue adhesives, wound dressings or transdermal delivery devices. This carefully planned research and training program in a network of leading academic and industrial (BASF, AkzoNobel, UGRO) partners will ensure that young researchers are given an excellent training in a pioneering research domain of high scientific and technological relevance, where Europe can take a leading position.";2822328,36;2822328,36;H2020-MSCA-ITN-2014;/MSCA-ITN-ETN;LEIBNIZ-INSTITUT FUR POLYMERFORSCHUNG DRESDEN EV;DE;"THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;Akzo Nobel Decorative Coatings bv;LEIBNIZ-INSTITUT FUER NEUE MATERIALIEN GEMEINNUETZIGE GMBH;BASF SE;WAGENINGEN UNIVERSITY;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;TECHNISCHE UNIVERSITEIT EINDHOVEN;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;IMPERIAL CHEMICAL INDUSTRIES LIMITED;PANEPISTIMIO PATRON";"UK;NL;DE;FR;EL";;1;0;0;1;0;0 199322;692058;NOTRE;SIGNED;H2020-EU.4.b.;H2020-TWINN-2015;H2020;Network for sOcial compuTing REsearch (NOTRE);2016-01-01;2018-12-31;;"The vision of NOTRE is to develop a network that will strengthen and enhance the potential of the newly established Social Computing Research Centre (SCRC) at the Cyprus University of Technology (CUT) for stimulating scientific excellence and innovation capacity in the area of social aspects of computing. NOTRE proposes an interdisciplinary approach towards the close network collaboration between SCRC of CUT, a research active university in a low-performing member state, and four internationally-leading counterparts specializing in: (a) online social networks and their analysis; (b) entertainment, games, virtual reality and educational technologies; (c) Social Computing for social inclusion; and (d) Social Computing and social change. SCRC through this proposal does not only aim to access the core research groups of the leading counterparts, and their collaborators, but also recognizes the multidisciplinarity of the field and will try to establish itself as an intermediate between them. The NOTRE network will follow a series of interlinked activities, such as short term staff exchanges, expert visits and short-term on-site training, workshops, conference attendance, organization of joint summer school type activities, and dissemination and outreach activities. Such activities with world-renowned EU partners (IMDEA; MIRALab of Universite de Geneve; Institute of Computer Science of the Foundation for Research and Technology Hellas -FORTH-ICS; and the Department of Political Science of the University of Dusseldorf -UDUS), will be instrumental for significantly strengthening SCRC's research efforts, enhancing the network's innovation capacity and research profile, and stimulating scientific excellence in the emerging multidisciplinary field of Social Computing. The effective knowledge transfer and sharing through NOTRE will also push for research advancements linked to the Smart Specialization Strategy of Cyprus.";1000000;1000000;H2020-TWINN-2015;/CSA;TECHNOLOGIKO PANEPISTIMIO KYPROU;CY;"HEINRICH-HEINE-UNIVERSITAET DUESSELDORF;UNIVERSITE DE GENEVE;FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS;FUNDACION IMDEA NETWORKS";"DE;CH;EL;ES";;1;0;0;1;0;0 199022;675080;UCoCoS;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2015-EJD;H2020;Understanding and controlling complex systems;2016-04-01;2020-03-31;;"Europe faces major challenges in science, society and industry, induced by the complexity of our hyper-connected world. Examples are the climate change, infectious diseases, artificial interconnected systems whose dynamics are beyond our understanding such as the internet, the global banking system and the power grid. A demand of performance emerges at an unprecedented scale: collaborative sensors and robots so to ensure competitiveness of our European production industry, better management of our traffic flows, designing (de)synchronization mechanisms applicable in neuroscience, are examples illustrating the necessity to understand and control the dynamics of complex networks. However, this requires a fundamentally new kind of complexity science. The traditional way of reducing a system to its components fails when the global dynamics are determined mainly by the interactions. Moreover, an interdisciplinary approach is necessary as revealing common principles is key in getting grip on the complexity. The objectives of UCoCoS are to create a control-oriented framework for complex systems, and to define a common language, common methods, tools and software for the complexity scientist. Moreover, as the first training network on the theme, UCoCoS aims at i) creating a closely connected new generation of leading European scientists, capable of designing network structures and policies to affect the networks, and ii) initiating long-term partnerships and collaboration mechanisms leading to sustainable doctoral training. The UCoCoS approach builds on recent developments in three domains (control, computer science, mechanical engineering) and stems from the identification of a unique combination of expertise within the consortium. Every ESR performs a cutting-edge project, strongly relying on the complementary expertise of the three academic beneficiaries and benefiting from training by non-academic partners from three different sectors.";1537619,76;1537619,76;H2020-MSCA-ITN-2015;/MSCA-ITN-EJD;KATHOLIEKE UNIVERSITEIT LEUVEN;BE;"ECOLE CENTRALE DE LILLE;TECHNISCHE UNIVERSITEIT EINDHOVEN";"FR;NL";;1;0;0;1;0;0 197239;640497;HandsandBible;SIGNED;H2020-EU.1.1.;ERC-StG-2014;H2020;The Hands that Wrote the Bible: Digital Palaeography and Scribal Culture of the Dead Sea Scrolls;2015-11-01;2020-10-31;;"The discovery of the Dead Sea Scrolls has fundamentally transformed our knowledge of Jewish and Christian origins. The scrolls provide a unique vantage point for studying the dynamic and creative engagement with authoritative scriptures that were to become the Bible. They also offer evidence for a scribal culture ‘in action’. Palaeography can provide access to this scribal culture, showing the human hand behind what came to be regarded as holy texts. The main objective of this interdisciplinary project is to shed new light on ancient Jewish scribal culture and the making of the Bible by freshly investigating two aspects of the scrolls’ palaeography: the typological development of writing styles and writer identification. We will combine three different approaches to study these two aspects: palaeography, computational intelligence, and 14C-dating. The combination of new 14C samples and the use of computational intelligence as quantitative methods in order to assess the development of handwriting styles and to identify individual scribes is a unique strength of this project, which will provide a new and much-needed scientific and quantitative basis for the typological estimations of traditional palaeography of the Dead Sea Scrolls. The quantitative evidence will be used to cluster manuscripts as products of scribal activity in order to profile scribal production and to determine a more precise location in time for their activity, focusing, from literary and cultural-historical perspectives, on the content and genres of the texts that scribes wrote and copied and on the scripts and languages that they used. Through their scribal activities these anonymous scribes constructed a ‘textual community’ and negotiated identities of the movement behind the Dead Sea Scrolls. The exciting aspect of this project is the fact that it will, through the innovative and unconventional digital palaeographic analysis that we will be using, bring these scribal identities back to life.";1484274;1484274;ERC-2014-STG;/ERC-STG;RIJKSUNIVERSITEIT GRONINGEN;NL;;;;1;0;0;1;0;0 197554;675866;COINS;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2015-EID;H2020;Complex and Open Innovation for Networked Society;2015-10-01;2019-09-30;;"COINS European Industrial Doctorate partnership will create a sustainable platform for researchers to engage in collaborative production of knowledge by investigating challenges for managing processes of complex and open innovation created by advances in digital technology. Five Early Stage Researchers, accompanied by experienced, interdisciplinary and intersectoral group of supervisors will study development of innovation capabilities required for organizations of different types to effectively respond to institutional, social and technological complexity in innovation ecosystems. Fellows will benefit of rich and unique complementary training programme, which will enable them to pursue variety of professional careers in academia, industry, consultancy and public policy. They will especially benefit from competency and skills for professional innovation management and technology entrepreneurship. An ambitious outreach programme will equip all fellows with appreciation of the role of business, entrepreneurship and technology in society. They will become responsible researchers and leaders capable of finding solutions for some of the greatest challenges facing our planet. The COINS objectives will be achieved by establishing a long-term partnership between the University of Leeds and Ericsson AB. They are joined by technology start-up Diamentech.";1366439,4;1366439,4;H2020-MSCA-ITN-2015;/MSCA-ITN-EID;UNIVERSITY OF LEEDS;UK;ERICSSON AB;SE;;1;0;0;1;0;0 222090;838926;SUMAC;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Interplay between High-Temperature Superconductivity, Magnetism and Composition in Doped Cuprates;2020-09-01;2022-08-31;;The origin of high-temperature (high-T) superconductivity (SC) is one of the greatest unsolved problems in physics. The solution could potentially lead to room temperature SC with immense technological benefits. There is ample evidence that microscopic magnetic correlations and dynamics are coupled to high-T SC, but a true understanding remains. The proposed research focusses on the effect of dopants on magnetic and SC properties of La2-xSrxCuO4 (LSCO) cuprates. The main research question is: does the SC mechanism has its origin in the magnetic properties of the material? This will be tackled in three ways: 1) The applicant will determine if the new theoretical prediction of the SC transition temperature increase with very small impurity content is justified for LSCO. This whole new effect will strengthen the case for magnetism-induced SC. 2) The applicant will study the low-temperature magnetic phase of LSCO when SC is fully suppressed by doping and field to provide new insights into the nature of intrinsic magnetic tendencies of LSCO. 3) The applicant will synthesize single crystals of completely new cuprates by replacing Sr by Sn, Zr and Ga to study how the ionic radii affect the magnetism-SC interplay. The project involves crystal synthesis, XRD, VSM and transport measurements and has a strong focus on elastic and inelastic neutron scattering experiments and data analysis. The applicant’s physics background and PhD in materials chemistry provide a strong basis for the experiments. The interdisciplinary nature of UCPH creates the ideal environment: the main supervisor Prof. Lefmann is an expert in neutron scattering with decades of experience, has all necessary physical characterization equipment and is a well-appreciated academic teacher. All relevant chemistry infrastructure and knowledge can be found within UCPH and close collaborators. In return, the applicant’s expertise in materials and crystallography will be a great addition to the Lefmann group.;219312;219312;H2020-MSCA-IF-2018;/MSCA-IF-EF-ST;KOBENHAVNS UNIVERSITET;DK;;;;1;0;0;1;0;0 222139;839573;5G-ACE;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Beyond 5G: 3D Network Modelling for THz-based Ultra-Fast Small Cells;2019-09-01;2021-08-31;;5G-ACE is engineered to be a two year Standard European Fellowship (EF) that aims to strengthen the ER (Experience Researcher)’s repository of scientific and transferable skills to place him in a strong position towards professional maturity, either at the host (University of South Wales) by targeting an “Academic Position by Research”, or as an independent researcher at leading international research centres and universities in Europe. The personalized training will identify key use cases and frequency bands for THz-based mobile communications, develop new 3D network models that take into account spatial coupling by re-examining legacy engineering tools such as stochastic geometry through interdisciplinary design, and involve practical experimentation that will be implemented as scheduled secondments at Nokia Bell Labs (Belgium), and Sigint Solutions Ltd (Cyprus). To complement the scientific training, the ER’s skill set will be enriched through a tailor-made Personal Career Development Plan (PCDP) that not only includes the core transferable skills (e.g, academic teaching, IPR management, research commercialization), but will identify other relevant complementary skills to provide a well-rounded research personality ready to embark on his 5G legacy and beyond.;224933,76;224933,76;H2020-MSCA-IF-2018;/MSCA-IF-EF-ST;UNIVERSITY OF SOUTH WALES PRIFYSGOLDE CYMRU;UK;;;;1;0;0;1;0;0 222091;838892;MATISSE;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Multifunctional Hierarchically-Structured Systems for Energy Storage Devices;2019-07-08;2021-07-07;;The widespread use of portable devices, as well as the electrification of transport, require a new generation of energy storage devices that deliver higher specific performance than Li-ion batteries. By designing multifunctional materials that combine structural and electrochemical energy storage, an improvement in gravimetric and volumetric efficiency can be achieved. The research aim of this project is to develop Energy Storage Devices based on multifunctional hierarchically-structured systems. The success of the project will be driven by the combination of two strong and complementary areas of expertise: At Imperial and IMDEA, the fellow will work for 24 months in groups with an extensive experience of carbon and inorganic nanomaterials synthesis, modification, characterisation, and application, particularly on hierarchical systems. On the other hand, she will bring her own experience in developing and characterising electrodes and electrolytes for a wide range of batteries as well as supercapacitors. The interdisciplinary intersection of new materials chemistry, with electrochemical device engineering, and structural composite mechanisms, will provide a unique opportunity for rapid progress in both science and technology. The structural energy storage devices will be developed from technology readiness level 1 and to 4, in order to accelerate direct impact on industrial applications, for example in the automotive and electronics sectors. During the two-year project, the fellow and supervisor will disseminate their results to Industry, Academia and General Public through patents and articles in podcasts, newspapers and scientific journals. From the start, an individual career development plan for the fellow will be developed with the supervisor and will be reviewed regularly during the fellowship. Prof. Shaffer’s talents for both research and teaching will inspire the fellow to launch ambitious research and educational projects early in her academic career.;212933,76;212933,76;H2020-MSCA-IF-2018;/MSCA-IF-EF-ST;IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE;UK;;;;1;0;0;1;0;0 198289;675395;ENLIGHT-TEN;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2015-ETN;H2020;European Network linking informatics and genomics of helper T cells;2015-10-01;2019-09-30;;"ENLIGHT-TEN is a European Network Linking Informatics and Genomics of Helper T cells: our mission is to provide cross-disciplinary training in cellular immunology and big data analysis such that we train a new generation of researchers to fully exploit the power of emerging technological platforms. Our network of TEN beneficiaries combines T cell expertise with state-of-the-art technologies such as next generation sequencing (NGS), bioinformatics, multi-colour flow cytometry, preclinical models and tailored genome editing. Trainees will acquire a comprehensive knowledge in T cell immunology and the capacity to generate and interrogate big data sets as well as expertise in identifying novel biomarkers and developing therapeutic concepts. As such the training programme will provide an ideal stepping-stone for creative and innovative early stage researchers (ESRs) to enter and strengthen Europe’s academia as well as pharmaceutical and bioinformatics companies. The research focus of the network lies in the identification of extrinsic and intrinsic factors that control development, differentiation and plasticity of helper T cell subsets with particular emphasis on how T cell differentiation impacts on human diseases. The generation of large data sets is an emerging and challenging field, and there is high demand in both the academic sector as well as pharmaceutical companies for researchers to be able to analyse, integrate and exploit this rich source of information. ENLIGHT-TEN will combine the individual strengths of innovative laboratories and enterprises from complementary disciplines to provide unique interdisciplinary training for 13 ESRs, placing them at the forefront of this emerging field. Trainees will be empowered to perform cutting-edge analysis of the steadily increasing number of different T cell subsets, which play highly diverse and critical roles in the development of autoimmune diseases, making them a key target for pharmaceutical companies.";3354685,32;3354685,2;H2020-MSCA-ITN-2015;/MSCA-ITN-ETN;HELMHOLTZ-ZENTRUM FUR INFEKTIONSFORSCHUNG GMBH;DE;"MEDIZINISCHE UNIVERSITAET WIEN;INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE;GENOME RESEARCH LIMITED;EUROPEAN MOLECULAR BIOLOGY LABORATORY;QIAGEN AARHUS AS;THE BABRAHAM INSTITUTE;Bayer Pharma AG;INSTITUTO DE MEDICINA MOLECULAR JOAO LOBO ANTUNES;UNIVERSITY COLLEGE LONDON;TURUN YLIOPISTO";"AT;FR;UK;DE;DK;PT;FI";;1;0;0;1;0;0 198300;675676;HAoS;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2015-ETN;H2020;Holistic Approach of Spray Injection through a Generalized Multi-phase Framework;2015-11-01;2019-10-31;;"Development of fuel injection equipment (FIE) able to reduce pollutant emissions from liquid-fueled transportation and power generation systems is a top industrial priority in order to meet the forthcoming EU 2020 emission legislations. However, design of new FIE is currently constrained by the incomplete physical understanding of complex micro-scale processes, such as in-nozzle cavitation, primary and secondary atomization. Unfortunately, today’s computing power does not allow for an all-scale analysis of these processes. The proposed program aims to develop a large eddy simulation (LES) CFD model that will account for the influence of unresolved sub-grid-scale (SGS) processes to engineering scales at affordable computing time scales. The bridging parameter between SGS and macro-scales flow processes is the surface area generation/destruction occurring during fuel atomisation; relevant SGS closure models will be developed through tailored experiments and DNS and will be implemented into the LES model predicting the macroscopic spray development as function of the in-nozzle flow and surrounding air conditions. Validation of the new simulation tool, currently missing from today’s state-of-the-art models, will be performed against new benchmark experimental data to be obtained as part of the programme, in addition to those provided by the industrial partners. This will demonstrate the applicability of the model as an engineering design tool suitable for IC engines, gas turbines, fuel burners and even rocket engine fuel injectors. The proposed research and training programme will be undertaken by 15ESRs funded by the EU and one ESR funded independently from an Australian partner; ESRs will be recruited/seconded by universities, research institutes and multinational fuel injection and combustion systems manufacturers that will represent in the best possible way the international, interdisciplinary and intersectoral requirements of the Marie Curie Action guidelines.";3857734,84;3857734,84;H2020-MSCA-ITN-2015;/MSCA-ITN-ETN;CITY UNIVERSITY OF LONDON;UK;"ETHNIKO KENTRO EREVNAS KAI TECHNOLOGIKIS ANAPTYXIS;IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE;KARLSRUHER INSTITUT FUER TECHNOLOGIE;DELPHI AUTOMOTIVE SYSTEMS LUXEMBOURG SA;UNIVERSITAET STUTTGART;UNIVERSITY COLLEGE LONDON;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;MITSUBISHI HITACHI POWER SYSTEMS EUROPE GMBH;CHALMERS TEKNISKA HOEGSKOLA AB";"EL;UK;DE;LU;FR;SE";;1;0;0;1;0;0 198262;674973;DEMETER;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2015-ETN;H2020;Training Network for the Design and Recycling of Rare-Earth Permanent Magnet Motors and Generators in Hybrid and Full Electric Vehicles;2015-09-01;2019-08-31;;Hybrid and Full Electric Vehicles ((H)EVs) are essential for the transition towards sustainable e-mobility. The permanent magnets in motors/generators of (H)EVs are either NdFeB or SmCo magnets, which contain large quantities of rare earths, which are critical metals with the highest supply risk for Europe. As highlighted by the European Rare Earths Competency Network, recycling of rare-earth magnets from (H)EVs should receive top priority. Reclaiming of rare-earth magnet motors/generators used in (H)EVs is a major challenge because the magnets are difficult to remove from the assemblies. The conventional hydrometallurgical routes for the recovery of rare earths from End-of-Life permanent magnets have a high environmental impact due to inefficient use of chemicals, whereas the conventional pyrometallurgical routes for the production of magnet master alloys are energy-inefficient. DEMETER, the European Training Network for the Design and Recycling of Rare-Earth Permanent Magnet Motors and Generators in Hybrid and Full Electric Vehicles, concurrently develops (1) innovative, environmentally-friendly direct and indirect recycling strategies for the permanent magnets in the motors and generators of (H)EVs that are currently already on the market and (2) design-for-reuse solutions for motors and generators in the (H)EVs of the future. An intersectoral and interdisciplinary consortium of leading EU universities, research institutes and manufacturers from the automotive and magnet sector trains 15 Early Stage Researchers (ESRs). The research challenges include the development of hydrogen-based grain-refinement technologies to produce nanograin magnets directly from scrap magnets, the recovery of rare earths from SmCo and NdFeB magnets of motors/generators by ionometallurgical methods, and the design of motors/generators with reusable magnets, where the designs are based on 2D and 3D flux paths as well as non-traditional materials.;3802512,24;3802512,24;H2020-MSCA-ITN-2015;/MSCA-ITN-ETN;KATHOLIEKE UNIVERSITEIT LEUVEN;BE;"INSTITUT POLYTECHNIQUE DE GRENOBLE;INSTITUT JOZEF STEFAN;THE UNIVERSITY OF BIRMINGHAM;MAGNETI LJUBLJANA PODJETJE ZA PROIZVODNJO MAGNETNIH MATERIALOV DD;AALBORG UNIVERSITET;VALEO EQUIPEMENTS ELECTRIQUES MOTEUR SAS";"FR;SI;UK;DK";;1;0;0;1;0;0 198277;675179;TASPPI;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2015-ETN;H2020;Targeted small-molecule Stabilisation of Protein-Protein Interactions;2016-02-01;2020-01-31;;The goal of the TASPPI European Training Network (ETN) is the establishment of a highly interdisciplinary research and educational training platform for early stage scientists in the Chemical Life Sciences to overcome the inherent boundaries between academia and industry and to increase their employability in both areas. To this end we have teamed up in a consortium comprising 5 partners from industry (AstraZeneca, GlaxoSmithKline, UCB, Lead Disocvery Center, Taros Chemicals) and 6 partners from academia (Universities of Dundee, Eindhoven, Leeds, Lille, Prague, and Siena). The scientific objective of the multi-sectorial Training Network is the development and implementation of a multidisciplinary technology platform bringing together structural molecular biology, chemical biology, cell biology, synthetic chemistry, and medicinal chemistry for the identification of Small-molecule Stabilizers of Protein-Protein Interactions (PPIs) as a novel class of therapeutic agents and basic research tool compounds. With this new technological approach we aim to address a number of unmet medical needs in the areas Cancer, Neurodegenerative Diseases (Alzheimer’s, Parkinson’s), Pulmonary Diseases, Inflammation and Metabolic Diseases (Diabetes).;3342369,6;3342369,6;H2020-MSCA-ITN-2015;/MSCA-ITN-ETN;TECHNISCHE UNIVERSITEIT EINDHOVEN;NL;"UNIVERSITA DEGLI STUDI DI SIENA;UCB BIOPHARMA SPRL;UNIVERSITY OF DUNDEE;ASTRAZENECA AB;LEAD DISCOVERY CENTER GMBH;UNIVERSITY OF LEEDS;TAROS CHEMICALS GMBH & CO KG;UNIVERZITA KARLOVA;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS";"IT;BE;UK;SE;DE;CZ;FR";;1;0;0;1;0;0 196924;662725;IBSEN;SIGNED;H2020-EU.1.2.1.;FETOPEN-RIA-2014-2015;H2020;Bridging the gap: from Individual Behaviour to the Socio-tEchnical MaN;2015-09-01;2018-08-31;;"Developing models of real-world societal scenarios and systems is a key topic in the research agenda of social sciences, but is hindered by the lack of controlled experimentation with large groups of people. IBSEN will provide a breakthrough by building a repertoire of human behaviour in large (1000\ persons) structured groups using controlled experiments. To that end, we will develop a novel setup for large groups of people that will provide an experimental protocol, the necessary software and analytical tools to allow us to deal with thousands of people at the same time. We will apply our setup to specific research questions, focusing on novel phenomenology that may arise in large systems as compared to typical smaller ones, to find the rules that govern human behaviour in those cases, including the influence of social context and individual identity on them. We will assess our approach by building a model of human interaction in groups based on the behavioural rules we have found. The project requires a high-degree of interdisciplinarity; accordingly, the team consists of physicists, economists, social psychologists, and computer scientists. On the other hand, this is a high-risk project, as the experimental design may prove unfeasible for really large systems and extracting meaningful data from the participants’ actions may not be possible. Notwithstanding, encouraging results in some pilot studies run by partners underpin the scientific feasibility of the concept and approach. If successful, researchers will be able to build on our findings to develop a human behaviour simulator, a technology providing a basis for socio-economic simulations that would radically change many fields, from robotics to economics, with technological and societal impacts, including policy-making in socially pressing issues. We will thus lay the foundations to kick start a new way of doing social science for the problems arising in a technologically highly connected society.";2663237,75;2663237,25;H2020-FETOPEN-2014-2015-RIA;/RIA;UNIVERSIDAD CARLOS III DE MADRID;ES;"THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;UNIVERSIDAD DE ZARAGOZA;UNIVERSITAT DE VALENCIA;AALTO KORKEAKOULUSAATIO SR;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;UNIVERSITEIT VAN AMSTERDAM";"UK;ES;FI;NL";;1;0;0;1;0;0 197246;641640;EJD-FunMat;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2014-EJD;H2020;European Joint Doctorate in Functional Materials Research;2015-06-01;2019-05-31;;"EJD-FunMat is a European Joint Doctoral programme in the field of functional materials research. EJD-FunMat is embedded in an existing research network, with previous experience in co-tutelle doctorates , but the project will add new major elements, with the strategic aim of becoming a permanent reference European Joint Doctoral School in Materials Science and beyond. The key innovative aspects of the programme are: - Research in PhD clusters: The 15 PhD projects are grouped into 6 thematic clusters: Photocatalysis, Transparent Conductors, Lead-Free Piezoelectrics, Photonics, Cellulose-based Polymers, Bone Tissue Engineering. Each cluster has 3-4 academic, and several industry partners, thus forming a small-scale collaborative project. This concept will (i) will be a practical training in interdisciplinary teamwork for the PhD candidates and (ii) provide a critical mass of researchers with the potential to achieve breakthrough research and innovation, compared to individual PhD projects. Additional, locally funded PhD projects will be added to the clusters. - Industry partner for each PhD: All PhD candidates will spend time in industry research laboratories, and will interact with industry throughout their project. - Joint supervision rules centered on a series of common Deliverables for all PhD candidates, to be achieved during the PhD project - Training in eco-design and life-cycle analysis of materials: topics such as critical raw materials and materials recycling have become crucial issues - Training in project and risk management - Training in industrial intelligence, entrepreneurship and innovation skills - Development of a sustainable framework for a joint PhD School. This strategic goal is based on 4 components: - scientific excellence - development of a legal framework for exploiting the research results - joint rules for co-tutelle PhDs, and joint PhD diplomas - attracting additional funding for PhD scholarships, during and after the project";3779224,56;3779224,56;H2020-MSCA-ITN-2014;/MSCA-ITN-EJD;UNIVERSITE DE BORDEAUX;FR;"UNIVERSITE DE LIEGE;INSTITUT POLYTECHNIQUE DE GRENOBLE;UNIVERSITE CATHOLIQUE DE LOUVAIN;LUXEMBOURG INSTITUTE OF SCIENCE AND TECHNOLOGY;UNIVERSITE DU LUXEMBOURG;UNIVERSIDADE DE AVEIRO;KARLSRUHER INSTITUT FUER TECHNOLOGIE;TECHNISCHE UNIVERSITAT DARMSTADT";"BE;FR;LU;PT;DE";;1;0;0;1;0;0 196958;665066;DigiArt;SIGNED;H2020-EU.3.6.3.;REFLECTIVE-7-2014;H2020;The Internet Of Historical Things And Building New 3D Cultural Worlds;2015-06-01;2018-11-30;;"DigiArt seeks to provide a new, cost efficient solution to the capture, processing and display of cultural artefacts. It offers innovative 3D capture systems and methodologies, including aerial capture via drones, automatic registration and modelling techniques to speed up post-capture processing (which is a major bottleneck), semantic image analysis to extract features from digital 3D representations, a “story telling engine” offering a pathway to a deeper understanding of art, and also augmented/virtual reality technologies offering advanced abilities for viewing, or interacting with the 3D models. The 3D data captured by the scanners and drones, using techniques such as laser detection and ranging (LIDAR), are processed through robust features that cope with imperfect data. Semantic analysis by automatic feature extraction is used to form hyper-links between artefacts. These links are employed to connect the artefacts in what the project terms “the internet of historical things”, available anywhere, at any time, on any web-enabled device. The contextual view of art is very much enhanced by the “story telling engine” that is developed within the project. The system presents the artefact, linked to its context, in an immersive display with virtual and/or with augmented reality. Linkages and information are superimposed over the view of the item itself. The major output of the project is the toolset that will be used by museums to create such a revolutionary way of viewing and experiencing artefacts. These tools leverage the interdisciplinary skill sets of the partners to cover the complete process, namely data capture, data processing, story building, 3D visualization and 3D interaction, offering new pathways to deeper understanding of European culture. Via its three demonstration activities, the project establishes the viability of the approach in three different museum settings, offering a range of artefacts posing different challenges to the system.";3056765;2354147,5;H2020-REFLECTIVE-7-2014;/RIA;LIVERPOOL JOHN MOORES UNIVERSITY;UK;"VULCANUAV LIMITED;HELLENIC MINISTRY OF CULTURE AND SPORTS;ETHNIKO KENTRO EREVNAS KAI TECHNOLOGIKIS ANAPTYXIS;ARCHEOLOGIE ANDENNAISE;PIX4D SA;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS";"UK;EL;BE;CH;FR";;1;0;0;1;0;0 197250;642688;SAWTrain;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2014-ETN;H2020;Dynamic electromechanical control of semiconductor nanostructures by acoustic fields;2015-06-01;2019-05-31;;"The dynamic modulation of semiconductor structures using vibrations provides a powerful tool for the control of the materials properties required for novel functionalities. Surface acoustic waves (SAWs) with GHz-frequencies and micrometre-size wavelength can be generated using piezoelectric transducers fabricated with standard integrated circuit technology. Their small propagation velocity and high sensitivity to disturbances confined to a superficial region have long been exploited in electronic signal processing and sensor applications. The SAW-induced modulation of the electro-optical properties of semiconductor structures is now been used for a wide range of applications including advanced sensors, the control of chemical processes, as well as the coherent control of carriers, spins, photons, and phonons down to the single-particle level. The latter are presently been exploited for different functionalities including advanced waveguide modulators, tuneable optical resonators, and single-electron pumps and single-photon sources. SAWTrain puts together leading groups from Europe, Asia and North America working on SAWs on semiconductor and related nanostructures to create a PhD training network. The synergy resulting from the expertise of these groups will provide PhD students with training opportunities far superior to those offered in existing PhD programmes. Training in research skills with secondments at different hosts will cover state-of-the-art research in the interdisciplinary areas of basic physics, materials, technology, and device concepts related to SAWs. This will be achieved by exposing the trainees to multiple secondments, mandatory co-supervision from different institutions, including a non-academic mentorship. The coordinated training will further contain topical courses, schools, conferences, and workshops and be complemented by measures to develop key competences and transferable skills, fostering the future career plan of the young researchers.";3855693,24;3855693,24;H2020-MSCA-ITN-2014;/MSCA-ITN-ETN;UNIVERSITAET AUGSBURG;DE;"THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;FORSCHUNGSVERBUND BERLIN EV;UNIVERSITEIT TWENTE;UNIVERSITAT DE VALENCIA;CONSIGLIO NAZIONALE DELLE RICERCHE;TOSHIBA RESEARCH EUROPE LIMITED;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;UNIVERSIDAD POLITECNICA DE MADRID;CHALMERS TEKNISKA HOEGSKOLA AB";"UK;DE;NL;ES;IT;FR;SE";;1;0;0;1;0;0 194593;649538;CATCH-EyoU;SIGNED;H2020-EU.3.6.;YOUNG-5a-2014;H2020;Constructing AcTive CitizensHip with European Youth: Policies, Practices, Challenges and Solutions;2015-09-01;2018-09-30;;"The proposal will investigate young people’s views of the EU and of their role in building the EU through their participatory practices at EU, national, regional and local levels. These issues will be examined from an interdisciplinary perspective (Political Sciences, Sociology, History, Media and Communications, Education, Psychology) as building blocks for a new and groundbreaking conceptualization and theoretical model of youth active citizenship in the EU, including “psychological” citizenship and practices of social and political engagement. To achieve this aim, the proposal will adopt an innovative approach combining traditional theoretical hypothesis testing with empirical-phenomenological analysis and allowing to integrate the perspectives of young people, as co-producers of knowledge, with those of researchers and other stakeholders. A wide range of research methods will be used including documentary and media analysis, interviews and focus groups, a cross-national longitudinal study, ethnographic case studies of participatory practices and a socially innovative intervention. These quantitative and qualitative methods will allow to develop a new, robust and cutting-edge conceptualization of youth active citizenship in the EU and new evidence-based multilevel integrated theoretical model. This approach will offer a multifaceted understanding of the different factors influencing the perspectives of “native EU citizens” and the ways in which they engage in society, leading to groundbreaking changes in the ways in which youth engagement, participation and active citizenship are understood. Moreover, the project will provide policy makers with a set of evidence-based ideas, recommendations and instruments to integrate young people’s perspectives into various areas of policy-making. The findings of the project will thus fully cover the challenges, scope and impact of bringing the EU closer to its young citizens and boosting their participation.";2498786;2498786;H2020-YOUNG-SOCIETY-2014;/RIA;ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA;IT;"TARTU ULIKOOL;Masarykova univerzita;ETHNIKO KAI KAPODISTRIAKO PANEPISTIMIO ATHINON;LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE;FRIEDRICH-SCHILLER-UNIVERSITAT JENA;UNIVERSIDADE DO PORTO;OREBRO UNIVERSITY;FORUM NAZIONALE DEI GIOVANI ASSOCIAZIONE";"EE;CZ;EL;UK;DE;PT;SE;IT";;1;0;0;1;0;0 222184;840383;ISULO;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Innovative Statistical modelling for a better Understanding of Longitudinal multivariate responses in relation to Omic datasets;2020-03-01;2023-02-28;;In medicine and agronomy, there is a growing interest in identifying biological mechanisms involved in the evolution of traits along time. Nowadays, this challenging objective is achieved through the acquisition of high-dimensional –omic datasets from various biological levels, and with the collection of phenotype measures along time on the same individuals, so-called longitudinal data. A new research focus is emerging with the objective to analyze jointly these two types of data. In this project, we propose to develop innovative statistical methods to simultaneously analyze these types of data and to deal with their respective characteristics. Novel methodologies will be developed by combining statistical concepts from linear mixed model and variable selection in a Bayesian framework, and by incorporating or inferring biological relationships. The first aim will focus on the analysis of one or more longitudinal outcomes with one –omic data. Flexible modeling for approximating time-varying covariate effects combined with variable selection approaches will be proposed. Thus, a better understanding of the relationships along time between the outcomes and the relevant covariates will be reached. The second objective is to investigate the integration of multiple –omic datasets for explaining one univariate outcome, then one longitudinal response variable, and finally multivariate longitudinal outcomes. Bayesian hierarchical modeling with prior distributions allowing to capture relationships among –omic datasets will be investigated and new relationships among –omic datasets will be explored. The developments and findings of this project research will greatly contribute to the statistical and biological domains. New generic statistical methods will be developed and will be available for transversal applications in various fields. Finally, this project will highlight the added value brought by a collaborative and interdisciplinary work with experienced researchers.;275619,84;275619,84;H2020-MSCA-IF-2018;/MSCA-IF-GF;CENTRE DE COOPERATION INTERNATIONALE EN RECHERCHE AGRONOMIQUE POUR LEDEVELOPPEMENT - C.I.R.A.D. EPIC;FR;;;;1;0;0;1;0;0 216098;777803;GYPWORLD;SIGNED;H2020-EU.1.3.3.;MSCA-RISE-2017;H2020;A global initiative to understand gypsum ecosystem ecology;2018-01-01;2021-12-31;;"Gypsum soils occur worldwide and represent natural laboratories of evolution and ecology. The unusual mineral content of gypsum soils is a significant barrier to the growth of most plants, and yet these soils host highly diverse endemic floras that have evolved independently on five continents. Nevertheless, these ecosystems are poorly understood compared to those of other unusual substrates. Little is known about the conservation status of gypsum floras, the potential impact of climate change on them, and their responses to mitigation and restoration. We propose an integrated global study of the ecology and evolution of plant and lichen life on gypsum, including eight gypsum-rich regions from four continents that differ in geological origin, climate, and flora. We will 1) assess the plant and lichen diversity of gypsum; 2) investigate the evolutionary origins and assembly of these floras; 3) evaluate potential adaptive mechanisms on gypsum, the functional structure of gypsum plant and lichen communities, and the processes regulating gypsum ecosystem function; 4) analyse the responses of gypsum communities to global change drivers and explore how gypsum ecosystem restoration/conservation may help mitigate the effects of global change; 5) promote the study of gypsum ecosystems; and 6) communicate the ecological and conservation value of these ecosystems to the public. With the involvement of gypsum experts from 18 academic and non-academic organizations from 11 countries, this project provides an innovative, integrative, and interdisciplinary approach to address key questions in gypsum ecosystem ecology, evolution, and management. The project thus strengthens existing international collaborative networks and consolidates Europe’s leadership in gypsum ecosystem research, including management and conservation plans and the identification of traits for crop improvement on gypsum soils, enhancing its attractiveness as a leading destination for related R&D";738000;724500;H2020-MSCA-RISE-2017;/MSCA-RISE;AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS;ES;"MINISTRY OF AGRICULTURE, RURAL DEVELOPMENT AND ENVIRONMENT OF CYPRUS;ANKARA UNIVERSITESI;UNIVERSITA DEGLI STUDI MEDITERRANEA DI REGGIO CALABRIA;UNIVERSIDADE DE COIMBRA;UNIVERSIDAD DE ALMERIA;UNIVERSIDAD REY JUAN CARLOS;ANOIKTO PANEPISTIMIO KYPROU (OPEN UNIVERSITY OF CYPRUS)";"CY;TR;IT;PT;ES";;1;0;0;1;0;0 196943;664565;EE-IT;SIGNED;H2020-EU.4.a.;WIDESPREAD-1-2014;H2020;EE-IT - Centre of Excellence on Connected Digital Economy;2015-06-01;2016-05-31;;"We propose a teaming partnership between Estonia and Edinburgh University (UK) in the area of IT to advance the global connected digital economy. Edinburgh is the leading IT research School in the UK with an excellent record for innovation and economic impact. Estonian funding agency ETAg is coordinating the partnership involving also the two highest ranked universities in the Baltic States. Estonian IT research has grown to be interdisciplinary and competitive, succeeding in IT as well as health-IT programmes. This has been achieved through the cultivation of excellence amongst the staff and consistent government policy to utilise structural funds to develop IT research and Innovation in Estonia. Impact of the new CoE will be built on national and global scale by further developing the achievements of Estonia on IT. Estonia has developed IT solutions for e-society utilising electronic identity and signatures, and simple modular communication architecture for service provisioning that have enabled many pioneering solutions from automated tax returns and national e-health platforms to internet voting. Estonia has developed an excellent start-up culture, as reflected by the development of high growth companies in the past decade, including Skype, GrabCAD, Cybernetica etc. Last but not least, Estonia is now a host to two prominent units, the NATO Cyber Defence Centre (CCDCoE, 2008) and the EU Agency for Large-Scale IT systems (EULISA, 2012). All this shows that the environment in Estonia is capable of supporting digital companies to reach “escape velocity” from the local economy and create global impact, as well as in an excellent position to absorb the additional research and training capacity. The envisioned CoE has two primary aims: to synergise and build critical mass in key multidisciplinary IT research areas in Estonia to realise an internationally competitive IT research sector; and to link to the economy to develop a dynamic cluster around IT excellence.";492794;492794;H2020-WIDESPREAD-2014-1;/SGA-CSA;SIHTASUTUS EESTI TEADUSAGENTUUR;EE;"TARTU ULIKOOL;TALLINNA TEHNIKAULIKOOL;THE UNIVERSITY OF EDINBURGH";"EE;UK";;1;0;0;1;0;0 195789;659425;EMPIREHURIGHTS;CLOSED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Empire and Human Rights: Colonization and Sovereignty in a global Iberian Empire (1580-1640);2016-08-01;2018-07-31;;This project is about human rights in history. The concept and doctrine of human rights as such are a recent creation, only formulated and codified after World War II. The main purpose of this project is to seek early manifestations and perceptions of human rights, in the way they came into existence in the political and juridical culture of early modern Europe. The best way is to take as reference the process of construction of European overseas empires in the sixteenth and seventeenth centuries. Because of its very nature, several issues were inherent to this process that are today considered in the scope of human rights, such as indigenous rights, slavery, religious differences and violence. How did European nations, which were themselves involved in a turmoil of conflicts about their own cultural and religious identity, dealt with these problems? How did governments, decision-makers, theologians, jurists, military, merchants and common people who settled overseas, thought and acted in this regard? And how did the peoples and rulers who watched the arrival of Europeans and suffered the violence of imperial and colonizing processes thought and acted? This research project is mostly focused on the period 1580-1640, when Portugal and Spain became united under the Catholic Monarchy, thus creating an Iberian empire of an almost-global dimension. This allows the analysis of a variety of cultural and geopolitical contexts (Brazil, Mexico, Mina, Sri Lanka, the Persian Gulf, India and the Philippines). It also allows seeking the roots of human rights problems and conceptions outside the frame of reference (Northern and Protestant Europe) that has been mostly considered by this scholarship. On the other hand, by historicizing the concept of human right, we hope to bring some new and different insights to the interdisciplinary approach to this topic, in addition to the perspectives currently offered by international relations, political science and international law.;148635,6;148635,6;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;UNIVERSIDADE DE EVORA;PT;;;;1;0;0;1;0;0 195750;659213;LIVING LASERS;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Living cell lasers: intracellular lasing induced by natural and polymeric microscopic resonators;2015-08-01;2017-07-31;;"Can a living cell be turned into a laser? By aiming to coalesce biological cells with laser light, the most versatile tool that modern photonics has developed, LIVING LASERS explores entirely new ways to develop fully biocompatible lasers. The ability of vitamins, bacteria and even living cells to generate laser light has been recently demonstrated by the supervisor of the project, Prof Malte Gather. However, these and other experiments with active biological gain media are so far limited by the rigid and synthetic nature of the optical resonators, an essential part of any laser device. Introducing lasing in living cells independent of external resonators necessitates a conceptual change of the laser design. This is realized by internalization of microscopic resonators that will transfer the optical feedback directly into the cell. It is the main goal of this interdisciplinary project, located at the interface between material sciences, laser physics, photonics and biology, to demonstrate autonomous single cell lasing. Consequently, LIVING LASERS can be expected to start a whole new field in biophotonics and will help to overcome the boundaries between living nature and nowadays highly artificial and harmful laser technologies.";195454,8;195454,8;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;THE UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS;UK;;;;1;0;0;1;0;0 222332;842112;IaM NUBIAN;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Identity and Memory in Christian Nubia: A study on strategies of (self-)presentation and preservation of the past in medieval African society;2019-09-01;2021-08-31;;In 652 CE the successful expansion of Islam into Africa was halted at the gates of Dongola. While the historical significance of this ‘Nubian dam’ is well known, its sociocultural dimension also for subsequent developments in the region remains completely unexplored. IaM NUBIAN addresses this gap by examining how Nubian identity was shaped in the aftermath of this world-historical event and how it changed over time to witness the rise to glory and eventual fall of Christian Nubia in the 15th century. Using the extensive, but hardly exploited written evidence (documentary and literary) produced inside and outside Nubia in 4 languages (Greek, Coptic, Old Nubian, and Arabic), I will study textual and contextual means of expressing ‘Nubianness’ in 4 case studies on (1) linguistic strategies of (self-) presentation, (2) gender-determined identity, (3) the role of inscriptions in public space, and (4) how external sources presented Nubians. For the first time in Nubian studies, traditional historical disciplines (e.g. philology, papyrology, epigraphy, history) will be combined with insights from social sciences (sociolinguistics, identity and memory studies) and statistics to unlock the sophisticated interplay of text and context that underlies the studied writings. Moving well beyond the boundaries of current knowledge and approaches, IaM NUBIAN shifts the focus from the political-religious to the sociocultural to understand the historical processes that shaped medieval Nubian society. IaM NUBIAN is best executed in the Leiden Institute for Area Studies with its interdisciplinary approach to studying society at large, while Freie Universität Berlin offers crucial additional digital humanities and sociolinguistic expertise. Through an intensive cooperative and interactive research and training programme I will gain crucial linguistic, disciplinary, and professional skills, which will put me in position to obtain an ERC Consolidator Grant and a permanent academic position.;187572,48;187572,48;H2020-MSCA-IF-2018;/MSCA-IF-EF-ST;UNIVERSITEIT LEIDEN;NL;;;;1;0;0;1;0;0 222100;839062;NOCEANIC;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Key factors driving particulate organic matter fluxes and related nitrogen losses in the main anoxic oxygen minimum zones of the world oceans;2019-05-01;2021-04-30;;Nitrogen loss fuelled by sinking particulate organic carbon (POC) is a key mechanism that drives biogeochemical cycles in anoxic oxygen minimum zones (OMZs). However, little is known about what controls this mechanism because of the challenges involved in observing it. Noceanic aims to improve current knowledge by exploiting – for the first time – time-series of optical proxies of POC and physicochemical data collected by autonomous profiling floats (i.e. “BGC-Argo”). This data acquired at unprecedented temporal and vertical resolution will generate new insights into the biogeochemical linkages between POC fluxes and N losses. Ultimately, Noceanic will contribute to reducing uncertainties in the mechanistic prediction of N losses and deepen understanding of the biogeochemical response of oceans to ongoing OMZs expansion. Noceanic will combine models, field and remote-sensing data. From field data, optical POC relationships will be tuned and then used to convert optical proxies of POC into POC fluxes. Remote-sensing data will be exploited to model surface POC formed by photosynthesis and assess its source of variability. From these elements, POC fluxes in anoxic OMZs (> 100 m) can then be translated into N losses. Finally, temporal changes in N losses will be explained in terms of the main factors driving the formation of POC and its export to anoxic OMZs. These innovative interdisciplinary activities will establish a two-way exchange of knowledge between the Researcher and the host institution, and enhance their European and international network of collaborators. An expected outcome of Noceanic is its impact on the European strategy for global ocean observations by promoting the inclusion of OMZs – a critical shift because OMZs expansion is affecting the oceans’ role in mitigating the Earth’s climate and the size of fish stocks, ultimately inflicting consequences on European society.;196707,84;196707,84;H2020-MSCA-IF-2018;/MSCA-IF-EF-ST;SORBONNE UNIVERSITE;FR;;;;1;0;0;1;0;0 222124;839376;EMPaTHY;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;use of multiscale modElling to Minimize coke ProducTion during the methanol-to- HYdrocarbon process;2019-11-01;2021-10-31;;"The methanol-to-hydrocarbon (MTH) process is a versatile catalytic process that are gradually playing a more important role in the economy. However, an important factor that is inhibiting the profitability of MTH is accumulation of coke in the pores of the catalyst during operations. To reduce or eliminate the coke formation during MTH operations, it is necessary to have a detailed mechanistic insight into its cause of formation. In this proposal, I will achieve this insight through a computational modelling strategy. I will study the mechanism of the MTH process at various time- and length scales, using various computational methodologies. I will use computational fluid dynamics (CFD) to study the fluid flow at the reactor scale and the diffusion in the macropores. I will use kinetic Monte Carlo (kMC) and molecular dynamics (MD) to study the diffusion in the meso- and micropores. Finally, I will use density functional theory (DFT) to study the reactions at the active sites. The processes studied at the various length scales will be coupled together through a multiscale methodology. Multiscale modelling has steadily evolved over the past decade, but the concept is still at the proof-of-principle stage where the methodology has been demonstrated for simple test systems such as CO oxidation. The methodologies that will provide data to the multiscale simulation, CFD, kMC, MD, and DFT have all reached a high level of maturity. Now is the right moment to use a multiscale methodology to couple these methodologies together and solve the problem of coke formation in the MTH process. The potential outcomes are the following: 1) an understanding of how coke is formed in the MTH process; 2) a larger acceptance in the catalysis community to use multiscale modelling in the design of new catalysts; and 3) tighter interdisciplinary collaborations.";171473,28;171473,28;H2020-MSCA-IF-2018;/MSCA-IF-EF-ST;POLITECNICO DI MILANO;IT;;;;1;0;0;1;0;0 222433;843798;FarGo;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;'Farming God's Way': Cultivation and religious practice in contemporary South Africa;2019-08-01;2022-07-31;;With this project, I will to study how religious agents engage with every-day challenges connected to food security, environmental decline and climate change. Via ethnographic methods, I will examine religious attitudes to environmental concerns through the case of Pentecostal Christian farming in South Africa. By investigating Pentecostal Christians’ methods of combining biblical principles and secular management approaches, I aim to provide a unique analysis of how Christian farming shapes religious practices that strive for social and ecological sustainability. Situated against a dichotomy between man and nature in Christians traditions historically, the proposed project will generate novel theoretical insights into how religious agents’ relationship to materiality today is manifested. Moreover, the project will demonstrate how the interplay between Christianity and farming produce novel social relationships in the intersection of religion, gender and race. As a religious scholar in the intersection of theology and social science, I understand how religious ideas and practices relate to identity-making, culture and social interactions. I have studied Pentecostal Christianity in Eastern Africa, so I have a robust and field-tested methodological and theoretical framework for investigation of Christian farming in South Africa. The Centre of African Studies at UCPH will be the perfect setting for this project due to its expertise on the material aspects of religion as well as climate and environmental changes. At this centre, I will have the opportunity to improve both my professional maturity and interdisciplinary skills. In addition, the fellowship will allow me to develop transferable skills in relation to project management, administration and teaching—skills that will enhance my career prospects within, as well as outside, academia.;328968;328968;H2020-MSCA-IF-2018;/MSCA-IF-EF-CAR;KOBENHAVNS UNIVERSITET;DK;;;;1;0;0;1;0;0 222256;841164;COLLECTITUDE;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Building the collective at times of precarity: precarious labour and its countermovements;2019-11-01;2021-10-31;;"The COLLECTITUDE project aims to analyse current andThe COLLECTITUDE project aims to analyse current and future transformations in the world of work at times of precarity, by researching the relationship between precarisation, on the one hand, and agency and social change, on the other, developing a new analytical perspective that is able to articulate this double movement and to capture both national and transnational social processes underway. It will address this double movement by focusing on the case of Portugal and by undertaking a comparative analysis of two professional groups that occupy a specific space in current models of capitalism, assuming a set of common trends throughout various countries, while representing two distinct sectors of the workforce: the construction industry, a labour-intensive sector, whose jobs are mostly unskilled, low-wage and insecure; and the creative industry, whose work is highly qualified, though intermittent and often unprotected. The project will be developed at a civil society organisation (A3S) and proposes an interdisciplinary, participatory and multi-method approach, involving a systematic process of progressive focusing: collection and analysis of quantitative macro data; ethnography of project work, based on participant observation and in-depth interviews; document analysis; and focus groups. The project will investigate: a) the political economy of precarity, and its relation with project work; b) the relationship between the precariousness of work and the precarity of livelihoods; c) how collective agency and different initiatives of social and solidarity economy unfold under precarious forms of labour; d) paths of intervention, updating the debates on the welfare state models. The final purpose is to advance knowledge on the futures of work and the future of social Europe, developing an analytical model for framing precarious work and collective agency and a social agenda for shaping the futures of work and society.";159815,04;159815,04;H2020-MSCA-IF-2018;/MSCA-IF-EF-SE;ASSOCIACAO A3S;PT;;;;1;0;0;1;0;0 222454;844179;TUNICS;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;The expression of cultural cross-fertilization in Egyptian clothing of the 7th-10th centuries AD.;2019-09-01;2021-08-31;;"The TUNICS project explores the impact of cultural cross-fertilization between the diverse populations in Egypt in the Early Medieval period (7th - 10th centuries AD) through an innovative, comparative study of the tunics, the basic garment in Ancient Egypt, and items par excellence to express their wearers’ identity. TUNICS will be the first comprehensive study of clothing from this period in Egypt and will provide a systematic overview of an almost entirely unexplored field in Egyptian archaeology. Both comparative, experimental archaeology and innovative digital research methods will be used to fully investigate the relationship between the garments and their wearer. This research will be primarily object-based and the comparative analysis of data gathered from various museum collections and archaeological sites will not only enhance the insight in technical crafts knowledge, but will also contribute to the understanding of the development of ancient garments and offer a unique perspective to explore different aspects of cultural identity and society. The TUNICS project is hosted by the University of Copenhagen’s Centre for Textile Research (CTR) a world-wide renowned institute in the field of ancient textile studies. The project will benefit from the stimulating and interdisciplinary scientific environment, training opportunities and CTR’s international network. The comparative study will be communicated through a series of academic publications and conferences. An Open Access database will be accessible to professionals as well as to a broader audience with interest in costume and textile history.";219312;219312;H2020-MSCA-IF-2018;/MSCA-IF-EF-ST;KOBENHAVNS UNIVERSITET;DK;;;;1;0;0;1;0;0 222362;842599;BioSMaLL;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Biopolymers for the Generation of 3D Tissue Engineering Scaffolds by Solution Mask Liquid Lithography;2019-07-01;2022-06-30;;Three-dimensional (3D) printing in biomedical science has recently advanced the development of tailor-made implants. Designing structural and functional 3D constructs mimetic of both tissues and organs offers a genuine route to personalised implants, improving the patients' quality of life and reducing healthcare costs. While engineers have significantly progressed 3D printing methods, the barriers to progress include the limited variety of printable materials as well as the need for alternative low-cost printing technologies. BioSMaLL aims to address this through combining Solution Mask Liquid Lithography (SMaLL), a recent technology developed at the University of California Santa Barbara (UCSB), with the expertise of the applicant and the Royal College of Surgeons in Ireland (RCSI) in functional biopolymers and tissue engineering to develop bio-active scaffolds. The objectives of this global fellowship will be achieved by adaptation of BioSMaLL for newly designed biopolymers during the outgoing phase at UCSB . In a transfer of knowledge, BioSMaLL will then be established at RCSI and bespoke biocompatible scaffolds produced and validated during the incoming phase. The innovative approach will be facilitated by an interdisciplinary methodology at the interface of polymer chemistry, (bio)materials science, 3D printing and tissue engineering in two world-renowned groups. The career goal of the fellow to embark on a career in emerging biomedical technologies in a start-up company will be facilitated by a dedicated training programme across scientific methods as well as complementary training at UCSB and RCSI covering leadership, project management and commercialisation in addition to meetings with laboratory and management staff of the start-up company SurgaColl. The partners have a proven track record in training future leaders in materials science and healthcare aiming to make a difference and establish new technologies and innovative processes in Europe and beyond.;257561,28;257561,28;H2020-MSCA-IF-2018;/MSCA-IF-GF;ROYAL COLLEGE OF SURGEONS IN IRELAND;IE;;;;1;0;0;1;0;0 222156;839880;DAMAGE;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;seismic off-fault Deformation: A multi-scale iMAGing to constrain Earthquake energy budget;2019-12-01;2021-11-30;;Earthquakes are one of the deadliest geo-hazards in the world causing huge societal and economic impact. Destructive earthquakes are generally represented by ruptures which nucleate, grow and terminate along pre-existing faults with catastrophic strain energy release. Seismological observations and theoretical arguments demonstrated that most of earthquake energy is dissipated into heat by friction within the core of faults at depth. The remaining energy amount is the one driven to the Earth surface by seismic waves and associated to the generation of extensive DAMAGE in the vicinity of seismic faults. Vast research was recently performed to investigate on-fault mechanisms during earthquakes whereas much less has been done to constrain the physical processes and energy sinks associated to coseismic off-fault deformation. I propose here to systematically study off-fault coseismic damage in carbonates, which are the rocks where most of the destructive seismicity striking Europe is hosted. The proposed research is innovative since it tackles a scientific topic which was so far overlooked with a multiscale interdisciplinary approach combining: detailed field structural and geophysical characterization of exhumed active fault zones, compressive and tensile dynamic loading tests on carbonate rocks, and microstructural-petrophysical characterization of natural and experimental fault rocks. This integrated strategy will lead to build a wealth of novel datasets to quantify the damage structure and scaling relations of seismogenic fault zones in carbonates. Newly conceived rock deformation experiments will then help to determine the mechanical origin of coseismic damage in carbonates. The research will be conducted at Universit? Grenoble-Alpes with a secondment at University of Manchester. The experience of the supervisors and the equipment at both organizations will guarantee the successful progress of the research and my professional growth as independent researcher.;184707,84;184707,84;H2020-MSCA-IF-2018;/MSCA-IF-EF-ST;UNIVERSITE GRENOBLE ALPES;FR;;;;1;0;0;1;0;0 222254;841150;SHINEShift;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Shape-shifting of vesicles induced by artificial tubular networks;2019-07-01;2021-06-30;;The most commonly used artificial cell membrane models are vesicles. However, these static structures, consisting of a lipid bilayer surrounding a fluid, are poor in resisting mechanical stress. Enhancing their mechanical properties with a dynamic artificial cytoskeleton will both allow stabilizing their shape and transforming these passive objects into dynamic stimuli-responsive systems. In this MSCA project photo-responsive synthetic supramolecular tubules will be used as an artificial cytoskeleton inside vesicles. My aim is to develop stiff and at the same time responsive tubules based on cyclic peptide design that can grow and generate pushing forces during the fueling step, and disassemble when the fuel stops, both in a fully reversible manner. This cutting edge interdisciplinary project brings together several disciplines in chemistry, i.e. organic synthesis and supramolecular chemistry with colloidal chemistry (and/or microfluidics), and its scientific impact will spread through various fields – from supramolecular chemistry to material science (leap from static vesicles to dynamic ones), and synthetic biology (relevance for future applications in the field of artificial cells). My expertise as experienced researcher in the field of organic synthesis will be applied to the field of dynamic supramolecular systems based on photo-switchable compounds in which the host (Dr. Kudernac) has made notable recent progress. During this training-through-research project I will be able to learn the preparation processes for the vesicles and microscopy techniques that are fundamental for investigating (dynamic) supramolecular assemblies and which will further expand my horizontal skills. In addition, training activities during this fellowship will strongly enhance my leadership and transferable skills. Hence, the Fellowship will allow me to become a distinctive researcher in a highly competitive scientific environment.;187572,48;187572,48;H2020-MSCA-IF-2018;/MSCA-IF-EF-ST;UNIVERSITEIT TWENTE;NL;;;;1;0;0;1;0;0 222328;842094;WIMPACT;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Late medieval visionary Women's IMPact in early modern Castilian spiritual Tradition;2019-10-01;2021-09-30;;"WIMPACT has two main objectives. In the first place, make an exhaustive research gathering the manuscripts and early printed books on/by European Late Medieval Mystic Women (13th-14th cc.) present in Castile in the premodern period (second half 15th c.-early 16th c.) and catalogue them. In the second place, evaluate the impact that those writings had, firstly, in the Castilian religious communities affected by Ximénez Cisneros Observant reform (1492-1517) and, secondly, in the Carmelite reform, accomplished by major literary figures as Teresa de Ávila and Juan de la Cruz (second half 16th c.). The first aim will be achieved by making an in-depth search in catalogues and directly in convent libraries of Castile and other institutions with keep collections related with female monasticism. In doing this, the ER will use his philological expertise combined not only to correctly classify the books, but also to understand them in a specific reception context. The results of this first phase will be accessible by the scientific community by creating an ad hoc open access webpage. The second aim will be achieved by implementing an interdisciplinary methodology which also departs from the comparative philology, but which uses tools of different fields (especially, gender studies, sociology and religious studies) to interpret the impact of those writings had in premodern Castile. The relevance of WIMPACT for Horizon 2020 is twofold: in the first place, it implies a comprehensive, transnational perception of the cultural history of Europe, which crosses traditionally established national and chronologic boundaries. In the second, it studies the empowerment of women, their subsequent influence in the politics of the Castilian court and the role that they had in the Observant reforms undertaken in the period. Consequently, WIMPACT will provide a novel, deeper picture of the importance of the role of women in the development of European history.";174806,4;174806,4;H2020-MSCA-IF-2018;/MSCA-IF-EF-ST;HEINRICH-HEINE-UNIVERSITAET DUESSELDORF;DE;;;;1;0;0;1;0;0 222457;844238;ClassRockED;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Rocking in the Midwest: Transmitting and Performing Social Class in Rock Music Education;2019-09-23;2021-09-22;;"‘Rocking in the Midwest: Transmitting and Performing Social Class in Rock Music Education’ is an innovative and timely project. It seeks to examine the ways in which ideals and markers of social class are transmitted, negotiated and performed within a unique setting – that of a rock music school in the US Midwest. By examining a traditionally white working-class and often patriarchal musical genre within a decidedly middle-class context – a private school, whose costs and institutional structure present a barrier to access for lower-income students – it seeks to shine a light on the shifting production of class within a region whose working-class-ness has at times been considered both problematic and emblematic of conflicted class, race and gender relations in the post-industrial United States. This research understands music education and performance as a unique site of the construction and negotiation of class consciousness and identities. It will consider how class-coded meanings and narratives are attached to visual and sonic symbols within rock education and performance. These symbols include musical instruments, sounds, language, gestures and ideals of musicianship and performance. It will examine how these symbols are transmitted, embodied and performed within the context of the school’s rehearsals, lessons and showcase performances, with a particular eye to the role of the gendered body in processes of teaching, learning, listening and music-making. This project takes a unique and innovative approach, marrying anthropological and ethnomusicological methods and modes of investigation with theoretical and analytical perspectives from cultural sociology and gesture studies, drawing as well on existing knowledge and research within music education, sociology of music and the emerging field of popular music education, in order to inform a truly interdisciplinary interrogation of social class and music education in the twenty-first century American Midwest.";196590,72;196590,72;H2020-MSCA-IF-2018;/MSCA-IF-EF-ST;DUBLIN CITY UNIVERSITY;IE;;;;1;0;0;1;0;0 222227;840804;RUMIC;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Prebiotic Functional Enhancement of Rumen Microbiomes;2019-05-01;2022-04-30;;Dr. Greta Reintjes proposes to work with Dr. Wade Abbott at the Lethbridge Research and Development Centre of Agriculture and Agri-Food Canada, to investigate the Prebiotic Functional Enhancement of Rumen Microbiomes (RUMIC). Ruminates, specifically cattle and sheep, are significant contributors to food production systems worldwide, with the EU alone producing 7 million tons of beef per year. This major agricultural sector faces significant economic obstacles due to increasing food safety and public health concerns over antimicrobial use in livestock. RUMIC aims at addressing these concerns by investigating the promising strategy of prebiotic application in livestock production systems for improved animal health and production. Prebiotics function by modulating the gut microbiome of ruminants towards improved metabolism of feeds, competitive exclusion or mitigation of pathogens, and enhanced overall animal health. RUMIC will employ novel methods in, molecular ecology, analytical chemistry, bioinformatics and super-resolution and live-cell imaging to i) visualise and quantify the uptake of prebiotics by rumen isolates, ii) to culture-independently analyse the effect of prebiotics on simplified artificial rumens, and iii) to isolate and characterise microorganisms with specific carbohydrate degrading potentials to discover novel metabolic pathways and enzymes, with the overall goal of providing evidence-based solutions for rumen microbiome enhancements. RUMIC will facilitate a mutually beneficial, interdisciplinary exchange of scientific skills and knowledge between two leading research institutes in Canada and Germany. Furthermore, it will provide a unique research platform for Dr. Reintjes, an early career researcher, to pursue an independent research project, enabling the acquisition of new knowledge, improved communication skills, establishment of new collaborations, and widening her career perspectives to the academic and industrial sector.;251434,56;251434,56;H2020-MSCA-IF-2018;/MSCA-IF-GF;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;DE;;;;1;0;0;1;0;0 222391;843161;ElectroCatFlow;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Fluorination of Aryl Halide Compounds under Electrochemical-Flow Conditions;2019-09-30;2022-09-29;;Fluorinated arenes are an invaluable class of organic compounds with important applications in pharmaceuticals, agrochemicals, and materials. Additionally, fluorine-18 has secured its place as the important radionuclide used in positron emission tomography (PET), largely due to attractive physical and nuclear characteristics. Through the years, use of transition-metal catalysis has revolutionised the access to these challenging compounds. However reliance on expensive catalysts and ligands, elevated temperatures, extended reaction times, and limited substrate scopes remain unsatisfied. This project untitled “Fluorination of Aryl Halide Compounds under Electrochemical-Flow Conditions” or “ElectroCatFlow” aims to develop a novel method to access aryl fluorides using a transition metal-catalysed fluorination reaction of aryl halides under electrochemical-flow conditions. ElectroCatFlow is highly interdisciplinary, involves mechanistic investigations, and applications of electrochemical-flow techniques to afford a mild, efficient and inexpensive method compared to current strategies. This project will generate broad interest from academia and industry, and will lead to high impact publications including scientific papers and potential patents. Finally, ElectroCatFLow will also maintain and improve European´s excellence in fluorination, catalysis and flow chemistry by creating a synergistic collaboration between the partner and institutions. Besides, this proposal aims to significantly influence on the EU healthcare system given the relevance of fluorine based drugs have in the Society.;271052,16;271052,16;H2020-MSCA-IF-2018;/MSCA-IF-GF;TECHNISCHE UNIVERSITEIT EINDHOVEN;NL;;;;1;0;0;1;0;0 222150;839730;SemioMaths;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Towards a theory of mathematical signs based on the automatic treatment of mathematical corpora;2019-10-01;2021-09-30;;"The SemioMaths project aims at proposing a formal model for the automatic analysis of mathematical corpora, based on semiological theories and on recent advances in formal and computational linguistics, in order to provide a broad and solid framework for the philosophy and the history of mathematics especially concerned with the study of mathematical practices. In order to achieve this objective, the action includes advanced training in the technical fields concerned by the project, the study of various existing mathematical corpora, the development of concrete implementations of linguistic computational models on mathematical corpora, and the elaboration of the corresponding results in the form of both scientific articles and a software package. Scientific training will be achieved by following suitable courses and exchanging with the research community of the host institution; the study of corpora will be done in close collaboration with the research team of the host chair; models will be implemented using the institution’s advanced computing infrastructure and IT support; finally, a teaching activity will help to systematize the conceptual grounds of the proposed approach. As a result of its inherent interdisciplinarity, other than in the specific fields of philosophy and history of mathematics, an impact is expected from the connections to be established with the other fields with which this project is concerned (computational linguistics, computer science, logic), and between the corresponding scientific communities. In this way, the SemioMaths project will improve our comprehension of the relations between mathematical knowledge and empirical textual practices. This shall result in a better understanding of the singularity of mathematics as a human practice and of its role in society, thus ultimately helping to build new and original bridges between formal and natural sciences on one side, and the humanities on the other.";191149,44;191149,44;H2020-MSCA-IF-2018;/MSCA-IF-EF-ST;EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH;CH;;;;1;0;0;1;0;0 222198;840557;SUPREME;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Sustainable Polyesters and Renewable Terpenoid Monomers;2019-07-01;2021-06-30;;Synthetic polymers derived from petrochemical products are essential for the production of a wide range of consumer products. The demand for more sustainable and renewable monomers and polymers is currently increasing, because fossil feedstock will become scarce in future times, and the global legislation is putting an increasing stress on the use of certain monomers used in the polymer industry. The aliphatic polyesters represent one of the most appealing type of bioplastic materials, because of their general biocompatibility and facile hydrolytic degradation and, in this ambit, the use of terpenes as monomers or monomer-precursors is largely unexplored. The primary objective of this project, is the creation of new polyester formulations based on renewable and accessible terpene monomers to answer to the growing need for future generations of more functional and sustainable materials. Three renewable monomers have been selected, two derived from camphor and a new one from ?-elemene. Structurally new polyesters will be synthesized by ring opening (co)polymerization of these monomers, using catalytic systems based on cheap and health-friendly metals (Fe, Al). The use of the new ?-elemene based monomer will incorporate vinylic groups along the polymer chains, offering the possibility for post-modification of the obtained material. The success of the project is supported by the Experienced Researcher background in polymer synthesis with the Host experience in the discovery and catalytic valorization of new terpene scaffolds. The action will take place in an interdisciplinary and international environment, granting to the Experienced Researcher a solid train in scientific and soft skills needed for his future career. The results of the action will have a strong impact on the society, giving the opportunity to asses circular economy on a highly impact industrial sector, such as that of bio-polymers.;172932,48;172932,48;H2020-MSCA-IF-2018;/MSCA-IF-EF-ST;FUNDACIO PRIVADA INSTITUT CATALA D'INVESTIGACIO QUIMICA;ES;;;;1;0;0;1;0;0 222188;840425;STOPFIRE;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Emergency Decision Support System of Offshore Platform Fires;2019-12-20;2021-12-19;;"In this project, fire accidents on offshore oil and gas platform will be analysed to identify the typical fire scenarios, followed by numerical simulation on the temporal and spatial evolution of the fires. Secondly, the coupling mechanism between human behavior and fire development will be investigated to quantitatively characterize the impact of fire on people and other assets. Thereafter, based on fire numerical simulation and multi-agent theory, an evacuation simulation model of offshore platform fires will be proposed. Thirdly, the dynamic risk of offshore platform fire evacuation will be evaluated by considering both failure consequences and their probabilities. A risk warning model of offshore platform fire evacuation will be built based on the Wavelet Genetic Neural Network. Finally, a dynamic decision-making support system for fire emergency evacuation will be designed by integrating Computation Fluid Dynamic (CFD), multi-agent theory and the Virtual Reality (VR) technology. This project covers a wide range of disciplines including CFD, multi-agent-based evacuation simulations, probabilistic inference (Bayesian inference and system dynamic model) and the VR technology. This Individual Fellowship will significantly accelerate the development of interdisciplinary knowledge, innovative research skills and new career of the nominated Fellow.";224933,76;224933,76;H2020-MSCA-IF-2018;/MSCA-IF-EF-ST;LIVERPOOL JOHN MOORES UNIVERSITY;UK;;;;1;0;0;1;0;0 222329;842043;CatchGel;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Catch Bond Cross-linked Hydrogels;2020-01-01;2022-12-31;;Catch bonds are one of Nature’s truly remarkable designs, which exhibit increased adhesive force as tensile force is applied, in contrast to traditional slip bonds whose adhesive force decreases under similar conditions. On reaching a maximum applied force, the catch bond then reverts to traditional slip bond behaviour resulting in a catch-and-roll type action that bacteria and cells use to move in a targeted fashion along a particular surface. The current research project aims to transplant this behaviour from bacterial systems into bio-based synthetic polymer networks, allowing the development of truly biomimetic mechanically adaptable materials. The aims of the project will be achieved by exploring a number of recently identified bacterial catch bonds, isolating the specific amino acid sequence responsible for this behaviour and using them to functionalise bio-based polymer chains. Using the receptor-ligand complexes specific to each bacterial adhesive, dynamic polymer networks will be constructed that display an adaptable response to force as observed in bacterial catch bonds. This represents an important area of research, for whilst the observation of ‘catch’ bond behaviour is relatively recent, their ability to revolutionise biomimetic materials is enormous. Their behaviour under stress is reminiscent of that of smooth muscle during peristaltic motion and materials mimicking this behaviour have the potential to drive new developments in synthetic organ and disease model research. Thoughout this project, fundamental insights will be gained into the intrinsic workings of bacterial catch bonds, specifically environmental factors affecting their behaviour, as well as how their behaviour is modified or scaled by inclusion in a macroscale material. The interdisciplinary project aims to push the boundaries of biology and materials science, from the molecular to the macroscale.;304724,16;304724,16;H2020-MSCA-IF-2018;/MSCA-IF-EF-CAR;UNIVERSITAT BASEL;CH;;;;1;0;0;1;0;0 222108;839135;TRIDOS;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Targeted Radiotherapy Internal Dosimetry: A platform for individualized patient dosimetry and radiobiological assessment;2019-05-01;2021-04-30;;"In radiation therapy (RT), which is used in more than 50% of cancer treatments, the dose delivered to the tumour/normal tissue determines tumour control and toxicity. Targeted radionuclide therapy (TRNT) is an effective growing type of RT in which radiative compounds with high tumour affinity are administered to patients. While in external RT there are well-defined methodologies to accurately determine the dose, this is not the case in TRNT. Traditionally, TRNT dosimetry is obtained from simple biokinetic models, developed many years ago, and non-individualized dosimetric factors calculated in phantoms. This dosimetry is inaccurate and not patient individualized. The recent European council directive 2013/59/Euratom, transposed on Feb 2018, has clearly highlighted the need to accurately report all doses from radiopharmaceutical procedures, hardening the criteria of previous regulations. The objective of this project is to develop methodologies for the accurate, individualized dosimetry and radiobiological assessment of TRNT, shifting from the current paradigm of empirical treatment to the era of personalized treatment. This will be achieved by the following actions: a) adaptation of Monte Carlo codes for patient’s internal dose calculation, considering novel biokinetic models of the drug biodistribution; b) development and implementation of radiobiological algorithms to evaluate tumour control/toxicity; and c) implementation of a platform useful for the clinical practice, incorporating these models and allowing easy handling and user interactivity. To successfully address this, the researcher experience will be combined with the host organisation (FIDIS) capabilities, a leading biomedical research institute where the supervisor is already involved in TRNT research. FIDIS will also provide clinical data for the models development/validation, an interdisciplinary environment and a training program greatly contributing to re-enforce the researcher professional maturity";172932,48;172932,48;H2020-MSCA-IF-2018;/MSCA-IF-EF-RI;FUNDACION INSTITUTO DE INVESTIGACION SANITARIA DE SANTIAGO DE COMPOSTELA;ES;;;;1;0;0;1;0;0 222213;840713;Strong_Link;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Integrated Advanced Experimental and Data-Led Materials and Process Development for Advanced Stainless Steels and Hybrid Materials Joints with Nanostructures;2019-12-20;2021-12-19;;"The project targets at the critical problems in welding/joining of advanced stainless steels and complex material system through modern experiments, physical modelling and data-informed materials and interruptive processing development. The objectives: 1. To establish the effect of element solutions on the grain nucleation/growth and the interface parameters between different phases (Ferrite, Austenite and martensite) in the similar and dissimilar welding through quantum mechanics modelling. 2. To develop methods to quantify/predict the depletion of Cr elements around secondary phases and corrosion resistance, and the competitive mechanisms between key alloying elements (Nb, Cr, Mo) in phase formation at different temperatures. 3. Develop welded systems of dissimilar/hybrid materials for significant weight reduction through nanoscale structures of superior stiffness-toughness-corrosion performances beyond traditional limit; 4. To provide training on problem-specific physical based predictive simulation, phase field modelling and advanced analysis by the host/project partner and transfer knowledge from the ER on materials design at atomic and nano-scales from his previous research in leading labs in China and Japan. The outcome will promote the use of advanced stainless steels with significant long term social and environmental benefits, and direct scientific, industrial, economic impact. This programme offers an opportunity to cement collaboration between international award winning multidisciplinary research in the Host, the ER and intesectoral partners. If supported, this Individual Fellowship (IF) will significantly accelerate the development of the interdisciplinary research skills and career of the ER, transfer his expertise to new areas of research and new external collaborations. The methodology, outcome and dissemination of the project will contribute the development of deep data for Industry 4.0 for welding and materials, contribute the R&I in the EU.";212933,76;212933,76;H2020-MSCA-IF-2018;/MSCA-IF-EF-ST;LIVERPOOL JOHN MOORES UNIVERSITY;UK;;;;1;0;0;1;0;0 222270;841332;ScanRights;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Economic and Social Rights in Scandinavian Diplomacy at the United Nations, 1970-2000;2019-09-01;2021-08-31;;This project, called ScanRights, provides the first examination of economic and social rights in the multilateral diplomacy of the three Scandinavian countries: Sweden, Norway, and Denmark at the United Nations from 1970 to 2000. Through a transnational approach to multi-national archival research, the project seeks to understand why the Scandinavian countries increased their support for poverty reduction and economic and social rights at a time when egalitarian politics were on the decline elsewhere in the West. It does so through two main research objectives: First, it examines Scandinavian contributions to the debate on The New International Economic Order from 1974 to 1982 (O1). Second, it examines Scandinavian diplomacy on the Right to Development in the 1980s and 1990s (O2). In doing so the project makes three important contributions to the existing scholarship. First, it addresses the neglect of economic and social rights in the history of Scandinavian human rights diplomacy. Second, it adopts a transnational multi-archival approach that goes beyond the national histories. Third, it provides an examination of Scandinavian human rights diplomacy absent in the international scholarship. The project is designed to improve the researcher’s career prospects by broadening his scientific profile, strengthening his teaching and supervision skills, and furthering his professional development through training in transferable skills. It adopts a targeted strategy to disseminate and communicate the research results to different audiences. The implementation is secured through a comprehensive work plan and the strong commitment of the supervisor and host institution, which provides the optimal intellectual infrastructure, specialized in interdisciplinary research on human rights.;203852,16;203852,16;H2020-MSCA-IF-2018;/MSCA-IF-EF-ST;LUNDS UNIVERSITET;SE;;;;1;0;0;1;0;0 222399;843267;INF-CVD;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Chronic inflammation and cardiovascular risk;2019-09-02;2021-09-01;;"Cardiovascular disease is the leading cause of death and illness globally. Preventive therapies can avoid or delay the occurrence of cardiovascular events, provided that one can identify individuals at risk and intervene before problems manifest. Recent scientific developments have established that inflammation has a prominent role in the development of cardiovascular diseases; but routine screening of inflammatory markers to assess cardiovascular risk in the general population is currently unfeasible. It is known however that certain diseases cause high and chronic inflammation, and patients affected by these conditions may be at increased risk of cardiovascular events. Yet, studies so far have been limited by the relatively modest absolute numbers of patients affected, so that for many of these conditions evidence is insufficient to guide clinical decisions. The aim of this research proposal is to investigate the associations between a range of chronic inflammatory conditions and different types of cardiovascular disorders, by using one of the largest longitudinal healthcare datasets available for research purposes in the world. The study design leverages the potential of ‘big data’ to explore complex disease associations through a unique combination of skills – my own knowledge of epidemiology and experience with the studied data set; my host supervisor’s expertise in statistical models best suited for the analysis of longitudinal data; and interdisciplinary clinical expertise through an international network of collaborations. A better understanding of cardiovascular risks associated with chronic inflammatory conditions may help guidelines and clinicians to focus on patients for which screening and treatments are more likely to have an effect, and improve the prevention of cardiovascular diseases. Differences between conditions may further point towards biological functions underlying these complications and inform the design of future research.";178320;178320;H2020-MSCA-IF-2018;/MSCA-IF-EF-ST;KATHOLIEKE UNIVERSITEIT LEUVEN;BE;;;;1;0;0;1;0;0 222458;844184;ARCHPRIS;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Territories of incarceration. A comparative study of prison farms in rural Europe and a proposal for Flanders.;2020-01-30;2022-01-29;;"A Prison Farm (PF) is a correctional facility located in rural environments where inmates are employed in open-air manual work.Within the current European carceral archipelagos, mostly constituted of mass urban walled prisons and recent suburban super prisons, PFs are limited in number and scope and often disregarded by national and EU policies, and by academic studies. Yet, PFs show potential in addressing the EU's wills to: improve the current state of incarceration while reducing its scope; promote sustainable agriculture and rural development. The IF's objective is to tackle these 2 societal challenges with a pilot project for a network of detention farmhouses that will be tested in the territorial condition of Flanders, a EU region suffering from an increase loss of farms. The project adopts a research-by-design methodology and will follow a groundwork comparative study of the space of selected existing PFs in Belgium, Italy, and Finland, aiming at the acquisition and systematization of a currently missing knowledge on European PFs. The project will be based -while extending its scope to the rural condition- on the cutting-edge institutional model elaborated by the NGO De Huizen, whose proposal for a network of urban small-scale contextually integrated detention houses is challenging the current penal system in Belgium. The supporting network of the host and partner institutions (KU Leuven-Dept.of Architecture, VUB-Dept.of Criminology, De Huizen), and of key members from Belgian public authorities in the sectors of prison and rural development, constitutes a unique interdisciplinary milieu of knowledge and expertise that will guarantee the success of the IF.This will impact the fellow's career, evolving her expertise in the field of prison architecture while expanding her critical insight on broader theoretical themes around the empowerment of architecture in directing human behaviour and the relationship between architecture-institutions-large scale territory.";178320;178320;H2020-MSCA-IF-2018;/MSCA-IF-EF-CAR;KATHOLIEKE UNIVERSITEIT LEUVEN;BE;;;;1;0;0;1;0;0 222251;841021;HelpSeeking;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Ontogenetic and Phylogenetic Roots of Strategic Help-seeking;2020-09-01;2023-08-31;;Human altruistic helping has deep evolutionary and developmental roots: Both human children and our closest non-human relatives - chimpanzees - often pay a cost to benefit another individual. Previous research on helping has nearly exclusively focused on the helper, i.e. the individual providing the help. However, helping also involves someone who is being helped. A helpee is not just a passive recipient of help, but someone who can actively and flexibly increase the chances of being helped, for example by being strategic in whom to ask for help. When determining who is willing to help, two questions are of particular relevance: (a) How costly is it for the potential helper to help? (b) What is my relationship with the potential helper? Considering the costs of and one’s relationship to potential helpers is crucial when soliciting help. Although it can significantly improve an individual's fitness, it has never been studied systematically when it evolved in our evolution and how it develops over ontogeny. Thus, unraveling the phylogenetic and ontogenetic roots of human’s strategic help-seeking is the objective of the proposed project. Therefore, I would like to conduct two interdisciplinary projects with human children and chimpanzees. In Project 1, I will investigate whether considering the costs of potential helpers for providing help influences the decision whom to ask for help, with costs operationalised either as physical effort (Study 1) or material sacrifice (Study 2). In Project 2, I will study the effects of social relations to the potential helpers on the help-seeking desision, considering in particular friendship (Study 3) and dominance (Study 4). Using an innovative approach – combining observations of naturally occurring behaviors and carefully controlled experiments – this project will be the first to provide insight into the evolutionary and developmental roots of strategic help-seeking.;246669,12;246669,12;H2020-MSCA-IF-2018;/MSCA-IF-GF;DEUTSCHES PRIMATENZENTRUM GMBH;DE;;;;1;0;0;1;0;0 222485;842964;MINT;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Multifunctional Immunocompatible NanoTheranostics to modulate tumor microenvironment and improve treatment monitoring: A double blow to pancreatic cancer;2019-09-01;2021-08-31;;"Different nanomaterials were developed so far in particular against cancer, paid very little attention to their potential immunogenicity, to their final destiny, as well as to the importance of zero-delivery in unwanted places. Thus, there is still a huge disproportion between the present nanomedicine tools and the clinical requirements. The ambitious purpose of the MINT project is to develop immunocompatible tumor targeted zinc oxide nanocrystals (ZnO-NCs) coated by extracellular vesicles (EVs) with enhanced drug delivery capabilities to cancer cells, by disturbing the supportive tumor microenvironment of pancreatic cancer, one of the most lethal human malignancies. Moreover, ZnO-NCs is doped with transition metal elements to be probed for treatment monitoring. In recent years while several therapeutic advances were implemented in many cancer types, the scenario of pancreatic cancer remains unchanged. The main factor behind the limited efficacy of chemotherapeutics in pancreatic cancer is its complex microenvironment. We propose to deliver Hedgehog pathway inhibitor & vascular endothelial growth factor receptor kinase inhibitor simultaneously through the multifunctional EV-coated doped ZnO-NCs to deplete tumor stroma, normalize tumor vascularity and improve pancreatic cancer therapeutic index. The proposed Fellowship will enable a highly interdisciplinary collaboration between the Researcher, experienced in targeted therapy & pancreatic cancer biology, and the supervisor, pioneer in designing nanotheranostics. These working conditions will effectively promote the Researcher’s professional development, providing her with excellent new expertise in nanotheranostics and fundamental leadership skills, significantly widening her career perspectives. The project outcomes will be of tremendous benefit to the European biomedical sectors, bridge the current gap between the conventional therapies and the Frontier research in the field of cancer nanomedicine.";183473,28;183473,28;H2020-MSCA-IF-2018;/MSCA-IF-EF-ST;POLITECNICO DI TORINO;IT;;;;1;0;0;1;0;0 222243;840989;MariBet;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;La MaMa Experimental Theatre: a lasting bridge between cultures;2019-10-01;2022-09-30;;"MariBet is focused on the activity of La MaMa Experimental Theatre Club of New York, founded by Ellen Stewart (1919-2011) in 1961 in order to give voice to artists marginalized by both the institutional theatres of Broadway and the Off-Broadway scene: a theatre conceived as an integration point in overcoming cultural and geo-political barriers and engaging artists in a common artistical research. Nowadays La MaMa produces performances always addressed to current social issues like immigration and welcoming refugees. The topic of the research is then in line with the current European political situation marked by the debate on migration flow. Main objectives are: 1. fill the gap in the field of theatre studies with an in-depth study of the history of La MaMa on which there are no exhaustive investigations yet; 2. analyse its engagement in promoting intercultural dialogues both in the past and in the present. These objectives will be reached through an interdisciplinary research, combining the historical and semiological investigation to the sociological analysis of the issues related to the performances presented by La MaMa. This project is timely because the historical distance from the facts allows a critical objectivity in the study of the subject, the emerging interest on the comparison between Avant-Garde theatre and contemporary theatre, the principles investigated by La MaMa over the years still impact on our society today. The project (36 months) will be hosted at the Department of Cultures and Civilizations (CUCI - UNIVR, Italy) and in the Martin E. Segal Theatre Center (MESTC, Graduate Center – CUNY, US), involving the non-academic cultural institution La MaMa Experimental Theatre Club of New York. The detailed research and training program will be supervised by prof. Simona Brunetti (main supervisor) and by prof. Marvin Carlson (in US), both renowned scholars of theatre with expertise in History and Theory of Theatre.";251002,56;251002,56;H2020-MSCA-IF-2018;/MSCA-IF-GF;UNIVERSITA DEGLI STUDI DI VERONA;IT;;;;1;0;0;1;0;0 222212;840709;SymAcc;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Symmetries and Degrees of Freedom in Cosmic Epochs of Accelerated Expansion;2019-10-01;2021-09-30;;"Through theory and observations, it is well established that the universe undergoes accelerated expansion in its history. This accelerated expansion takes place in two different epochs. The first of these is the early epoch of inflation and the second is the current epoch of dark energy domination. Although methods of General Relativity, which is the classical theory of gravity, and Quantum Field Theory, which addresses matter interactions at quantum scales, have guided much of our understanding of the universe, they cannot fully address these epochs of accelerated expansion. In this project the objective is to identify the cosmological degrees of freedom that have a crucial role during inflation and dark energy. It proposes to achieve this goal by studying the ideal case of a spacetime that gives accelerated expansion, using recent methods in holography in order to (i) identify specific deformations from the ideal case that give rise to the cosmological degrees of freedom during inflation and dark energy separately; (ii) explore the generality of these deformations and their cosmological consequences using methods of renormalization group flows; (iii) address deformations in the context of time dependent and space dependent evolution separately to further improve the understanding on the nature of cosmological degrees of freedom. This interdisciplinary project proposes to use the principle of holography from String Theory which can open up a new way of studying cosmological perturbations, especially in the context of dark energy. By focusing on cosmological spacetimes, it will also address the validity of holography in new settings.";144980,64;144980,64;H2020-MSCA-IF-2018;/MSCA-IF-EF-ST;FYZIKALNI USTAV AV CR V.V.I;CZ;;;;1;0;0;1;0;0 222217;840737;TOK;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;The Creation of Tokens in Late Antiquity. Religious 'tolerance' and 'intolerance' in Fourth and Fifth Centuries AD;2019-09-02;2021-09-01;;"This innovative project aims to investigate the phenomenon of the production of late-antique tokens as objects embodying the relations between different religious identities in Roman society. In particular, the study focuses on the so-called “Vota Publica coinage” (or “Festival of Isis coinage”) and “Asina tokens”, both minted in the Roman West during the fourth century and perhaps the fifth century AD. These issues are still partly unpublished and furnish valuable data. Since the creation of these “pagan” objects took place during the gradual repression of polytheistic cults by a Christian government, the project will shed light on the question of religious freedom and on the dynamics of religious “propaganda” during an era that saw the transformation of the pagan Roman Empire into a Christian one. Unlike traditional approaches, religious politics will be examined through the innovative perspective supplied by the numismatic evidence of tokens, which, as an expression of relationships, exchanges and culture, contain a remarkable informative potential for the understanding of broader aspects within ancient communities. Through this lens, the project will focus on specific social, religious, and cultural experiences in the context of the “conflict” between pagans and Christians in the fourth and fifth centuries AD. The adoption of an interdisciplinary approach and the mobilization of intellectual tools forged by classical disciplines will help to formulate appropriate patterns and to develop an analytical inquiry on the psychological, social, religious and political changes and interactions revealed by tokens in the late Roman empire. This project will therefore make a historical contribution to current reflections on religious “tolerance” and “intolerance” that have a significant preponderance in societies past and present. Addressing a matter of continuing concern, the project will help inform contemporary debates in different fields of the scientific research";212933,76;212933,76;H2020-MSCA-IF-2018;/MSCA-IF-EF-ST;THE UNIVERSITY OF WARWICK;UK;;;;1;0;0;1;0;0 222320;842092;WIRED;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Wired: The Role of Infrastructure in the Tibetan Buddhist Revival in Contemporary China;2019-09-01;2021-08-31;;This project examines the critical and unforeseen role of infrastructure in the Tibetan Buddhist revival in contemporary China. Although both state-led development in minority regions and Tibetan Buddhist revivalism in China have been widely discussed, they are usually treated as separate realms of study, as if one represents material development and the other emphasizes immaterial perspectives. The main objective of my research is to show that these two features of Sino-Tibetan relations are in fact interlinked. I use an in-depth ethnographic method to explore the growing infrastructural connections between Tibet and China, from remote Tibetan regions to Chinese metropolitan areas, by looking at internet access, new construction, roadways, facilities, practices, and policies and examining their impact on the Tibetan Buddhist revival in China and vice versa. My study examines the much neglected relationship that exists between religious movements in society and the infrastructural projects of the state. In doing so, it provides not only an alternative perspective from which to understand religious movements and ethnic politics in the Chinese context, but, more broadly, offers a critical and theoretical reassessment of the relationships between materiality and immateriality, human and non-human agency, and object and subject. The University of Copenhagen is an ideal place in which to pursue my project. The Department of Cross-Cultural and Regional Studies uniquely combines interdisciplinary inquiry and study across Minority Studies, China Studies, Tibetology, and Religious Studies, all of which are crucial to my project. In particular, my project fits well with the research foci of the Department’s Center for Contemporary Buddhist Studies, a world-class research center led by Associate Professor Trine Brox, with a focus on the mediating role that Buddhism plays in materiality, spirituality, economy, and value across contemporary societies.;207312;207312;H2020-MSCA-IF-2018;/MSCA-IF-EF-ST;KOBENHAVNS UNIVERSITET;DK;;;;1;0;0;1;0;0 222313;841925;DIS2;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Disability and Disease during the 1918 Influenza Pandemic: Implications for Preparedness Policies;2019-06-03;2021-06-02;;A global influenza pandemic is imminent and public health preparedness plans that address the needs of vulnerable populations are indispensable. While researchers have documented socioeconomic and geographic variables that contribute to disparities in infection and mortality, there has been little to no investigation of disability as a risk factor during influenza pandemics, despite the warnings of epidemiologists that persons with disabilities would be at increased risk. Drawing on rich historical data from the 1918 influenza pandemic, this project addresses this gap through a novel interdisciplinary and mixed methods approach. Quantitative and qualitative analyses will explore differential outcomes based on forms of disability and institutionalisation. Results of demographic analyses and insights from archival, historical, and ethnographic literature will inform the construction of an agent-based computer simulation model that will help explain observed patterns and evaluate the effectiveness of potential interventions. A short visit will enable regional comparisons between Norway and Sweden and enhance theoretical and methodological links between epidemiological and disability research. The fellow will benefit from the expertise of a European centre of excellent research, the Centre for Welfare and Labour Research, at Oslo Metropolitan University, Norway. Building on the fellow's previous work and skills in both epidemic modelling and disability research, the project activities will lead to further development of the fellow's professional maturity, while the results will have a key impact on the advancement of multiple academic disciplines, and as called for in EU and UN policies, on the improvement of the citizen rights and health of persons with disabilities.;202158,72;202158,72;H2020-MSCA-IF-2018;/MSCA-IF-EF-ST;OSLOMET - STORBYUNIVERSITETET;NO;;;;1;0;0;1;0;0 222258;841210;AnxNPS;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Anxiety across childhood and adolescence: Neural, psychological, and social factors;2019-12-01;2021-11-30;;"Anxiety disorders are one of the most prevalent and chronic forms of psychiatric disorder. Critically, these disorders often have an early onset, with childhood and adolescence being the core period of developmental risk. Anxiety in this period can lead to academic and socio-emotional difficulties, as well as long-term mental health problems. Elucidating the developmental trajectories and aetiology of early anxiety is therefore of great importance. This project aims to further understanding of the neurobiological and psychological mechanisms through which anxiety emerges and is maintained across childhood and adolescence, as well as how atypical early social experience may increase risk. Multi-model techniques (neuroimaging, cognitive assessment, behavioural observation) incorporating interdisciplinary insights will be utilized to realize the following objectives in a longitudinal study of rhesus macaques varying in early social experience: 1) assess levels of anxiety over time; 2) track brain development over time and relate to concurrent and future anxiety; 3) assess attention bias to threat (ABT) over time and investigate its relationship with brain development and anxiety; and 4) consider effects of atypical early social experience on relationships between brain development, ABT and anxiety. Novel aspects of this project include the longitudinal investigation of brain development across the core period of risk for anxiety disorders, and consideration of how atypical early experience might modulate relationships between brain development, ABT, and anxiety. Project results will provide a more in-depth and nuanced understanding of early anxiety, which can be used to guide future human research and aid the design of more effective treatments and early interventions. Advanced training in neuroimaging and nonhuman primate behaviour will expand the candidate’s skill-set significantly, establishing their trajectory towards becoming an independent research leader.";196707,84;196707,84;H2020-MSCA-IF-2018;/MSCA-IF-EF-ST;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FR;;;;1;0;0;1;0;0 222162;840033;NaWaTL;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Narrative, Writing, and the Teotihuacan Language: Exploring Language History Through Phylogenetics, Epigraphy and Iconography;2020-06-01;2022-05-31;;This project deploys an innovative interdisciplinary mixed-methods approach to studying the cultural patterns of ancient Mesoamerican civilization. The study combines traditional comparative analysis of language history with quantitative phylogenetic methods, and with qualitative analyses from epigraphy and ethnohistory to answer a central question in Mesoamerican history: When and from where did the community of linguistic forebears of the Nahuatl-speaking Aztecs disperse in Central Mexico, and are they likely to have played a role in the development and/or downfall of the metropolis of Teotihuacan (ca. 150-600 CE)?;219312;219312;H2020-MSCA-IF-2018;/MSCA-IF-EF-RI;KOBENHAVNS UNIVERSITET;DK;;;;1;0;0;1;0;0 222153;839770;EWPWE;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Europe at War in Post-war Europe. Performing Greek Tragedies, Comedies and European Identity.;2019-09-01;2021-08-31;;"This project will examine the multiple ways in which contemporary western European theatre directors (in the UK, Germany, France, Belgium and Switzerland) have staged and continue to stage war with the help of ancient Greek dramatic scripts from the WW2 onwards. I will argue that such performances question and try to understand European identity. The three strands of this interdisciplinary project (in between Classical Reception Studies and Theatre Studies and mixing practice and theory) will cover past, present and prospective dramatic approaches of this question: 1/ academic research (archives, libraries, interviews) to analyse past performances; 2/ observation of contemporary productions in rehearsals; 3/ creative labs with students from Oxford, Paris and Li?ge to highlight how young Europeans are dealing with those materials. This will allow to propose a history of war on stage in post-war Europe, told through productions of ancient plays that seek, sometimes consciously indeed, to build a distinctly European identity. The fellowship will take place at the APGRD (Archive of Performances of Greek and Roman Drama, Faculty of Classics, UOXF) that is the best environment to manage such a project given its world-class database and archive of performances of Greek and Roman Drama that I will use and contribute to. This indisciplinary project will grant me the opportunity to work with some of the best researchers in Classical Reception Studies in the world (particularly with my supervisor Fiona Macintosh), strenghtening my academic network. I will improve my skills in this field and also in general European research management to become a mature researcher in Classical Reception Studies (since I have a PhD in Theatre Studies). Moreover, since I already have an extended experienc as a stage-director, this research-as-creation project will bridge my academic and artistic carreers and put me at the forefront of Theatre Studies.";212933,76;212933,76;H2020-MSCA-IF-2018;/MSCA-IF-EF-ST;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;UK;;;;1;0;0;1;0;0 222238;840903;FREEMIND;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Ferroelectric REsistors as Emerging Materials for Innovative Neuromorphic Devices;2019-06-03;2021-06-02;;"Neuromorphic computing such as deep-learning algorithms arise as a promising solution to treat the exploding amount of data generated worldwide, but at the cost of expensive time and energy budget on conventional hardware. There is an urgent need for a low-power, compact neuromorphic chip that can support bio-inspired computing: a network of cells collocating storage (non-volatility) and computing (synaptic plasticity). This work proposes to achieve such cell using a ferroelectric resistor, down-scaled to nanometer thickness to allow direct electron tunneling through the ferroelectric barrier (ferroelectric tunnel junction): the learning functionality (i.e. synaptic plasticity) will be implemented through the control of the distribution of the (non-volatile) ferroelectric domains. The fellow will bring her expertise in ferroelectric tunnel junctions and will combine it with IBM’s expertise in device and circuits integration and characterization, making use of the state-of-the-art equipment offered by their research center. In order to accelerate the creation of an end-to-end neuromorphic device, she will lead a collaboration with ETH Zurich and will benefit from their expertise in predictive physics-based modeling. The research project will aim at: (i) the demonstration of a non-volatile and plastic ferroelectric “synapse” made of Hf0.5Zr0.5O2 – a fully CMOS-compatible material, (ii) the development of models of individual cells and of a neural network and (iii) providing design guidelines for neuromorphic hardware based on this technology. The outcome will be to evaluate performances not only of individual synapses but of a neural network as a whole. Through the Action, the fellow will not only aim at creating a novel technology; but also at leading an interdisciplinary research project uniting complementary actors for an innovative solution to a society challenge.";191149,44;191149,44;H2020-MSCA-IF-2018;/MSCA-IF-EF-SE;IBM RESEARCH GMBH;CH;;;;1;0;0;1;0;0 222158;839799;TEXDANCE;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;TEXtiles in Etruscan DANCE (8th-5th centuries BC);2019-09-01;2021-08-31;;"TEXDANCE will explore Etruscan dance through textiles from 8th to 5th centuries BC. It will use the visual sources to analyse Etruscan society and its élite’s ritual practices in a multidisciplinary approach. This study will make us understand the movements of dance, their ritual functions, their diversity, their performativity and the social relations which intertwine. This is important to understand as textiles in Etruscan dance in particular reflect a different community organisation from the Mediterranean and contribute to question our contemporary European community organisations. Also, for the first time, the two-way transfer of knowledge between dance studies and costume studies will be connected via an innovative approach. The project combines three types of sources: primarily the iconographic representations as they constitute the most important documentation for Etruria, literary sources and archaeological evidence. TEXDANCE has seven objectives: 1. the types of dress and textiles used in dance; 2. dress motion; 3. the acoustics of textiles; 4. Etruscan fashion and dress identity; 5. Etruscan community organisation; 6. ritual textiles making; and, 7. the visuality of textiles. The comparative and interdisciplinary approach includes the history of dance, rituals and religion, performance studies, ethnoarchaeology, archaeoacoustics, sensory studies, motor praxeology, and visual studies. The application of new digital technologies is a crucial aspect with the opportunity to 3D model how cloths move in dance. Digital humanities will also play a fundamental role in the presentation and diffusion of the results that will be made available thanks to a fully open-access philosophy to the scientific community and the general public. Conceived as such, the project is fundamental for both the proposer and the hosting institution, and it will contribute to European excellence and competitiveness in the creation of a common and widespread European culture and history.";207312;207312;H2020-MSCA-IF-2018;/MSCA-IF-EF-ST;KOBENHAVNS UNIVERSITET;DK;;;;1;0;0;1;0;0 222097;838982;PapalEmotions;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Emotions, gender, and authority at the curia of Pope Innocent III (1198-1216);2019-09-02;2021-09-01;;By the end of the twelfth century, the papacy had become one of the most influential institutions in Latin Christendom. Using ideas and approaches from gender studies and the history of emotions, this interdisciplinary project investigates how the pope and his curia used emotions to communicate papal authority, and how this was shaped by contemporary ideas about gender. It focuses on the pontificate of Innocent III (1198-1216), which was a period of both crisis and renewal within the Latin Church. Scholars of clerical masculinity have fruitfully analysed depictions of emotional expression in central-medieval episcopal texts to determine how clerical authors used emotional signification to convey an exclusively male authority. Few studies, however, exist on papal emotions, and scholars have not examined the role played by gender in the ways in which central-medieval popes conveyed their authority. The project makes use of a variety of sources including papal letters, sermons, and biographies. These documents are rich with gendered emotional coding, and I focus on how expressions of sorrow, anger, and emotive pastoral imagery were used in instances when the pope faced challenges to his authority. I argue that examining expressions of emotion sheds light on how the papal curia’s rhetorical manipulation and use of discourses of masculinity influenced the way in which it communicated papal authority. In doing so, I provide an innovative framework for the use of emotional discourse to understand masculine hegemonic authority. This project will be developed at CGS Aalborg (host) and IAHR Vienna (secondment) to allow me to collaborate with outstanding researchers in the history of papal communication at these institutions, ensuring that my project is at the cutting edge of research and will develop my career. The results will be disseminated through peer-reviewed open access articles, a popular history magazine article, a podcast, and workshops for high-school pupils.;207312;207312;H2020-MSCA-IF-2018;/MSCA-IF-EF-ST;AALBORG UNIVERSITET;DK;;;;1;0;0;1;0;0 222267;841317;SENSE;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;BioSensing and rhizospherE – eNdosphere geochemical microprofiling of polychlorinated byphenils degradation by Soil microbiota upon stimulation of root Exudates;2019-06-03;2021-06-02;;"Phyto-rhyzo-remediation is a promising technology for pollutant clean-up provided by the plant holobiont, composed by the host plant and its microbiota. Plant root exudation is modulated by the pollution stress and has a key role in the activation of the microbial degrading metabolism. Despite the well documented role of the plant holobiont in ecosystem services, the complex interactions between host and microbiome are poorly understood, in particular in contaminated environments. SENSE is an innovative, interdisciplinary approach to sort out the time-spatial synergistic interplay within the plant holobiont components and the geochemistry of rhizosphere micro-niches supporting microbial degradation. The project will take place in a top-rated Italian research university and spans metabolomic techniques, biosensors, together with an original application of microsensor/sensor devices to profile the chemistry of the root microenvironments. The study will be applied to one of the largest sites in Europe contaminated by polychlorinated biphenyls (PCB), located in Italy. The research will be approached from two complementary angles: i) set up and application of bacterial biosensors to examine topology and dynamics of activation of the PCB degradation pathways upon stimulation by identified plant root exudates; ii) sensing the plant-modulated chemical micro-habitats through microsensor/sensor devices during plant-microbe interaction under PCBs stress. This will provide a proof of concept for the role of root exudates as boost of soil microbiome degradative potential. SENSE outcomes will provide a comprehensive understanding of the plant holobiont applied to environmental biotechnology, representing an opportunity for Europe to keep its leadership in research and green biotechnology. Additionally, this project will significantly enhance my skills and capabilities as experienced researcher in microbial and plant-sciences, to become a leader in this field";183473,28;183473,28;H2020-MSCA-IF-2018;/MSCA-IF-EF-ST;UNIVERSITA DEGLI STUDI DI MILANO;IT;;;;1;0;0;1;0;0 222123;839290;LangMix;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Language switching and script mixing: multilingual landscapes of medieval Scandinavia;2019-07-01;2021-06-30;;"The present project aims to investigate the encounter between the Latin and the native vernacular written culture in medieval Scandinavia, through phenomena of language and script switching in epigraphic sources. The spread of Latin is a pivotal point in the development of all European literate societies. Scandinavia represents a unique case study where Latin and the Roman script encountered and mixed itself with an 800 year old native tradition based on the local vernacular and the runic script. From being monolingual and monoscriptal, Scandinavia became multilingual and multiscriptal. Through an interdisciplinary framework to be developed in synergy with leading scholars at the University of Oslo, epigraphic methods completed by multimodal and sociolinguistic analyses within a linguistic landscape perspective will serve to determine: 1) the medieval writers’ multilingual and multiscriptal proficiency; 2) the status relationship between the Latin and runic written tradition; and 3) the ideological presuppositions and purposes of the use of different languages and scripts. For the first time, these phenomena will be studied systematically and through an unexplored combination of historical material and modern sociolinguistic methods. This will not only yield new insights in the multilingual literacy of medieval Scandinavia and on its underlying cultural and ideological aspects, but also in its significance in a European context. By embedding the Scandinavian case in the process of cultural and political formation of Europe, this project will also contribute to understand the common cultural heritage in modern European societies.";214158,72;214158,72;H2020-MSCA-IF-2018;/MSCA-IF-EF-ST;UNIVERSITETET I OSLO;NO;;;;1;0;0;1;0;0 222220;840772;ReMedIt;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Between rediscovery and recreation: Renaissance accounts of medieval Italian vernacular literary tradition (1476-1530);2019-09-01;2021-08-31;;"ReMedIt aims to provide the first historical reconstruction of the evolution of views on the medieval Italian vernacular literary tradition in Italy during the period that leads to the formation of an established canon of vernacular literary authors (1476-1530). The project focuses on the reception of the poetic tradition, in particular the extensive Italian lyric tradition (c. 1230-c. 1330) preceding Petrarch, one encompassing over two hundred authors. The project interrogates three main interrelated research strands: 1) the differing value judgements concerning the vernacular poetic past before Petrarch, both implicit ones (such as the selection of poets, their ordering, and the amount of attention afforded them in different poetic anthologies) and explicit comments and judgements; 2) the complex processes – material, interpretative, exegetical and cultural – that bring about the recovery of the medieval lyric tradition and generate knowledge related to it; and 3) the literary influence that this tradition exercised upon verse production during the same period 1476-1530 in the output of nine authors. In order to reconstruct the differing views regarding the genesis and historical development of the earlier Italian literary tradition, the project offers a novel interdisciplinary approach. It does this by integrating the study of how Renaissance poets were influenced by thirteenth- and fourteenth-century authors with an assessment of their critical reception and of the contemporary processes of recovery of their texts. In doing so, ReMedIt will offer a fuller and enriched understanding of this seminal period in the development of the history and codification of the vernacular literary tradition, thereby providing a case study that will be valuable for the study of other national literatures. Through a carefully constructed training-through-research programme the experienced researcher will expand her research interests broadening her chronological range.";212933,76;212933,76;H2020-MSCA-IF-2018;/MSCA-IF-EF-ST;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;UK;;;;1;0;0;1;0;0 222189;840424;EndoReproTox;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Embodied Ecologies: An Ethnographic Study of Reproductive Toxicity, Infertility, Endometriosis and Delayed Childbearing;2019-09-01;2021-08-31;;'This ethnographic project reframes the study of infertility by considering reproductive health as an environmental issue. It is specifically interested in the relationship between exposure to endocrine-disrupting chemicals (EDCs), infertility, and endometriosis, a common hormonal disorder that disrupts the female menstrual cycle and is strongly correlated with both infertility and EDCs. How are these links understood in expert and public contexts, and how do they factor into the way people make decisions about fertility and childbearing? By focusing on understandings of causality instead of treatments/technologies, and by conceptualizing health as an 'embodied ecology' instead of a product of individual choices and behaviors, this project has implications for health policy and public awareness as well as anthropological theory. Working with Diana Marre at the AFIN Research Group at the Universitat Aut?noma de Barcelona, the pre-eminent site for the interdisciplinary social study of reproduction, will provide me with the support and training to conduct this innovative research and reach professional maturity. Over twenty months of fieldwork consisting of interviews and participant observation in Barcelona, Europe's leading site for infertility treatments, with short fieldwork trips to California for an important comparative perspective, this project connects my prior experience researching reproductive decisions in California with demographic and health challenges affecting Europe and Western societies more broadly. Training will focus on proliferating my methodological skills and enhancing my ability to communicate across sectors and to the public, which will be enabled by AFIN's inter-sectoral connections with medical centers and its unique Center devoted to public outreach. Dissemination will consist primarily of three peer-reviewed articles, six conference presentations, two public talks, and two public newsletters.';160932,48;160932,48;H2020-MSCA-IF-2018;/MSCA-IF-EF-ST;UNIVERSITAT AUTONOMA DE BARCELONA;ES;;;;1;0;0;1;0;0 222397;843234;TAXON-TIME;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Rediscovering biodiversity: using big-data to trace taxonomic knowledge through time;2019-10-01;2021-09-30;;Few macroecologists would dispute the importance of taxonomy for their work. Yet most treat taxonomic classification as a static, although it is intrinsically dynamic and subject to periodic change. This inconsistency arises from the divergent objectives of both disciplines and hampers progress towards more robust estimates of species richness across biomes. TAXON-TIME aims to bridge the gap between taxonomy and macroecology. The project will scrutinize 250 years of botanical explorations in African and Amazonian rainforests and analyze the impacts of taxonomic reclassifications on the macroecological patterns of tree species abundance and richness. To this end, TAXON-TIME will apply cutting-edge methods of data-intensive research and integrate massive volumes of digital data of historical taxonomic discoveries and reclassifications that became available only recently. A probabilistic approach to data analysis will ensure the resulting biodiversity patterns account for the likelihood of taxonomic reclassifications across space and time. TAXON-TIME results can lead to a paradigm shift in macroecological research towards the adoption of a probabilistic, rather than deterministic, view of taxonomic reclassifications. The project is led by an Experienced Researcher (ER) with outstanding analytical and technical skills and relevant research experience on three continents. TAXON-TIME brings together an interdisciplinary team of leading scientists with complementary research skills in tropical ecology, macroecology and data-intensive research. Upon completion, TAXON-TIME will contribute to a paradigm shift in macroecology and provided the ER with an analytical toolbox tailored for the next generation of macroecologists, establishing the ER as a central actor in a unique cross-disciplinary research field, which has just began to emerge.;172932,48;172932,48;H2020-MSCA-IF-2018;/MSCA-IF-EF-ST;AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS;ES;;;;1;0;0;1;0;0 222422;843546;ABSREF;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Activity Based System Reliability Evaluation Flow;2019-06-01;2021-05-31;;This proposal envisions to foretell the reliability of electronic systems with high degree of accuracy by introducing a novel workload dependent aging aware simulation framework which has acceptable run-time. The framework is generic in nature and will enable one to perform system optimization in presence of multiple aging related phenomena including negative bias temperature instability, positive bias temperature instability, and hot carrier injection. Thus the benefits of the improved timing margin or guard-band incurred by this flow can be leveraged to further improve speed, power, durability of electronic systems and reduce cost. An efficient workload abstraction scheme will be employed which speeds up the transistor level degradation evaluation with accuracy comparable to that of cycle-accurate simulations. Using the device level degradation results, standard cell library characterization will be performed by statistical methods based on Design of Experiments and Response surface Modelling approach. The created workload dependent, aging aware cell libraries will be used to carry out static timing analysis and optimization. Critical path delay degradation evaluated under this framework will be compared with the corner based aging analysis to highlight the impact of the innovation. The framework will be validated using industry standardized, CPU intensive SPEC2006 benchmark suite run on top of multi-core industrial processor. Considering its interdisciplinary nature, the project will help bridge the gap between two disciplines: the device level reliability research and system level interactions. Working in highly international and intersectoral environment of the host IMEC, Dr. Mishra will enhance his professional skills to become a mature independent researcher.;178320;178320;H2020-MSCA-IF-2018;/MSCA-IF-EF-ST;INTERUNIVERSITAIR MICRO-ELECTRONICA CENTRUM;BE;;;;1;0;0;1;0;0 222129;839481;NEUTON;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;NEUTrino OscillatioN analysis at T2K and SuperKamiokande experiments: Can neutrinos explain the matter-antimatter asymmetry in the Universe?;2019-09-01;2022-08-31;;NEUTON is an interdisciplinary project aimed at getting a better knowledge of the NEUTrino OscillatioN phenomenon through the development and implementation of innovative neutrino interaction models in long-baseline neutrino oscillation experiments, while reducing experimental uncertainties, and shortening running time and experimental operation costs. This proposal will be jointly developed in collaboration with the renowned Super-Kamiokande and T2K experiments, the Institute for Cosmic Ray Research (ICRR, University of Tokyo) and the University of Seville. The research objectives are focused on: 1) the implementation of realistic neutrino-nucleus reactions models into experimental event generators to improve the determination of neutrino oscillation parameters and mass hierarchy, and 2) the discovery and measurement of CP-symmetry violation in the neutrino sector. The achievement of these objectives will be a crucial input towards understanding the matter-antimatter asymmetry of the Universe and other open questions in Physics, such as the search for dark matter through sterile neutrinos, the proton decay and the analysis of supernovae explosions. The precise knowledge of these properties in long-baseline neutrino oscillation experiments largely depends on an accurate description of neutrino interactions, which constitutes one of the largest experimental uncertainties. Accordingly, in NEUTON we will improve and implement the sophisticated SuSAv2-MEC neutrino interaction model in event generators (NEUT and GENIE), which has proved its capability to describe neutrino data in a wide energy range, being a promising candidate to reduce the experimental systematics needed to answer the above mentioned open questions in Physics as well as to significantly shorten the required running time and the experimental costs of current and next-generation neutrino experiments.;271227,84;271227,84;H2020-MSCA-IF-2018;/MSCA-IF-GF;UNIVERSIDAD DE SEVILLA;ES;;;;1;0;0;1;0;0 222421;843554;BIOMOSAIC;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;From Biopigments to BIOelectronics: MOdelling Semiconducting EumelAnin-based InterfaCes;2020-04-01;2022-03-31;;"The overall aim of this proposal is to build a comprehensive model of ionic and electronic transport in organic bioelectronics considering a prototypical material, eumelanin, as a proof of concept. Bioelectronic devices are used in nanomedicine for implantable, wearable and sensing applications. Eumelanin is a natural biocompatible semiconductor with great potential in bioelectronics due to its joint electronic and ionic conductivity. However, a full picture of its interactions with water and electrolytes and how these influence its semiconducting properties is still missing, thus holding back a systematic improvement of eumelanin-based devices. This project will provide the first unified picture of eumelanin’s mixed conduction by simulating electronic and ionic charge transport at device-relevant scales and combining them in a numerical model. This will be achieved through four innovative steps towards eumelanin characterisation: i) reactive molecular dynamics (MD) simulations will capture the details of water-eumelanin interactions; ii) a classical MD approach will describe ionic conduction in hydrated eumelanin; iii) electronic structure methods will relate eumelanin’s morphology to its electronic conductivity. iv) The previous insight will be combined in a model describing mixed conduction in eumelanin-based devices, allowing the formulation of general design rules for the development of new bioelectronic materials. Planned collaborations with leading groups in eumelanin bioelectronics will provide experimental data to build and validate the model, resulting in high-impact publications and contributing to European competitiveness in bioelectronics. The complementary nature of the researcher and host’s research profiles is instrumental in fulfilling the complex, interdisciplinary aims of the project. The Fellowship will allow the researcher to expand her knowledge beyond her existing skills, enabling her transition towards an independent academic career.";212933,76;212933,76;H2020-MSCA-IF-2018;/MSCA-IF-EF-RI;THE UNIVERSITY OF LIVERPOOL;UK;;;;1;0;0;1;0;0 222375;842868;PROSPER;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Politics of Rulemaking, Orchestration of Standards, and Private Economic Regulations;2019-09-01;2021-08-31;;PROSPER is an interdisciplinary project that seeks to understand the politics of rule-making in the global trade regime. It primarily aims to examine how the growth of internationalization of production networks enables private actors – i.e. multinational companies (MNCs) – to be active in the shaping of international economic policies, such as trade agreements and regulatory standards. PROSPER will primarily investigate the extent to which MNCs are able to orchestrate political mobilization of their subsidiaries for coordinated lobbying and impose rules and standards upon firms along their supply chains. Applying international political economy (IPE) insights from the fields of political science, economics, and international law, the projects proposes that firms’ globalization strategies and their degree of integration into global production networks significantly affect their ability to be active in shaping global rules and standards. In order to test the empirical implications of the proposed theory, PROSPER will employ a mixed-method research design using quantitative analysis and in-depth case studies. The project will construct a comprehensive new dataset of MNCs and triangulate the results achieved through statistical analysis via comparative cases studies. As a result, by combining insights from political science, economics, and international law, the project will help us understand the dynamics of economic globalization and the role of private actors in the global trade governance.;191149,44;191149,44;H2020-MSCA-IF-2018;/MSCA-IF-EF-ST;UNIVERSITAET BERN;CH;;;;1;0;0;1;0;0 222343;842234;FRUITFUL;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;On the evolution of fleshy fruits: An integrative test to assess the relative role of intrinsic and extrinsic factors in shaping fruit type;2019-06-01;2022-05-31;;"A trip to a grocery store exposes us to an outstanding diversity of fruits. While this variety was influenced by human selection during plant domestication, it mainly reflects strategies of seed dispersal that evolved over millions of years. Despite the huge variation in fruit color, shape, and size, common patterns can still be identified, especially the repeated evolution of fleshy fruits (e.g. olives, apples, tomatoes). Though this pattern is well observed, we are still exploring the role of different factors and their selective pressures. These can be intrinsic, as evolution of inherited genes determining fruit traits, or extrinsic, as the environment. To date, studies have focused on one or two major factors at a time, but their relative contributions requires an integrative analysis. FRUITFUL will dissect the evolution of fleshy fruits in the olive family. Oleaceae is the ideal study subject here because it presents a natural comparative set-up for fruit evolution: multiple lineages that independently evolved fleshy fruits; species living in a variety of environments; and diverse seed dispersers. Further, several genomes and transcriptomes of Oleaceae were recently released. In this project, I will: (1) identify independent transitions to fleshy fruit within a comprehensive phylogenetic framework of Oleaceae; (2) use phylogenomic approaches to analyze representative genes in species with fleshy or dry fruits, and test for switches in selective pressures in relation to trait transitions; (3) estimate the historical biogeography of the family, along with current environmental preferences of species, and their seed dispersers; and finally, (4) integrate all results in models of causal relationships, and identify direct and indirect effects, and their magnitudes, among variables and fruit type. FRUITFUL’s interdisciplinary research and novel integrative approach will provide new insights into understanding the patterns observed at a macroevolutionary scale.";295061,76;295061,76;H2020-MSCA-IF-2018;/MSCA-IF-EF-CAR;UNIVERSITE PAUL SABATIER TOULOUSE III;FR;;;;1;0;0;1;0;0 222260;841174;ReMIND;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Reactivating Neglected Heritages, Reweaving Unspoken Memories. A Study on the Adaptive Reuse of Former Asylums into “mind museums”.;2020-03-01;2022-02-28;;"ReMIND focuses on the potentials for ‘mind museums’(former asylums turned into museums)to provoke emotional responses in visitors and foster critical reflection on the histories and contemporary problems of dealing with mental illness (MI) in society.Its objective is to fill some relevant scientific gaps on the subject, as well as to conjoin complimentary disciplinary approaches from museum and exhibition design and museum studies and develop new research competence for me as fellow and for the host institution in the field of visitor studies. ReMIND explores the MI heritage landscape through asylums built in Europe from the mid-19th cent until the 60s’ deinstitutionalisation process in the psychiatric care system.Today, most of these buildings still stand where they were, often completely or partially abandoned, left to decay, and contributing to urban decline.ReMIND will survey the European landscape of MI heritage considering phenomena such as abandonment and reuse of historic asylums for cultural purposes.However, alongside this general desk-based overview, its main aim is to analyse former asylums that have been restored and reused as museums, specifically involving 2 indepth interdisciplinary pilot case studies.Nowadays we don’t have a sense of potentials for the responsible adaptive re-use of asylums and they are in danger.Likewise, once converted into museums, their role in effecting attitudinal change in visitors that may help to dismantle stigma and promote awareness toward MI has not been properly investigated.ReMIND addresses these gaps. To do so my study will integrate various disciplinary approaches to rethink adaptive reuse interventions and contemporary heritage conservation and valorisation practices.I will work at the intersection of different research fields, moving from Italy to UK at New Castle University to learn, deploy and contribute in implementing theories and methodologies related to heritage studies, visitor studies, and display analysis.";224933,76;224933,76;H2020-MSCA-IF-2018;/MSCA-IF-EF-ST;UNIVERSITY OF NEWCASTLE UPON TYNE;UK;;;;1;0;0;1;0;0 222453;844159;PALP;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Pathiana Archaeological Landscapes Project;2019-10-01;2021-09-30;;"This project focuses on the archaeology and history of the territory of Pathiana, a small (30x40km) region in southern Senegal which has played a key role in the history of the Senegambia over the last millennium. From the 12th to the early 20th C, and through four major socio-political disruptions, Pathiana survived as a political unit and centre of power, becoming a key player in the Atlantic trade in the process. Nevertheless, despite its key historical importance, Pathiana has never been archaeologically or historically studied, except for some limited excavations conducted as part of the applicant’s PhD. The proposed project aims to redress this situation by combing archival research with surface survey and recording of oral traditions amongst village elders. This will generate three interrelated datasets -historical European accounts and maps, local oral historical narratives, and archaeological survey data- which will be combined to achieve two main goals. Firstly, this project will rectify a major lacuna in our understanding of the Senegambia by systematically documenting the archaeology of Pathiana and its associated traditions. This will correlate for the first time the region’s intangible narratives with tangible remains and generate the chronologies and baselines for future research to build on. Additionally, this interdisciplinary dataset will be used to explore how the political structures of a small but powerful polity changed and adapted through seven centuries and three major societal upheavals, and how such structures were reflected in, and articulated through, the landscape. This project thus will generate highly significant data and interpretations concerning both the history of the Senegambia and wider debates on societal organization, political complexity, and the relationship between power and spatiality, as well as further exploring the long-standing dialogue between oral traditions, written sources and archaeology.";160932,48;160932,48;H2020-MSCA-IF-2018;/MSCA-IF-EF-ST;AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS;ES;;;;1;0;0;1;0;0 222216;840729;UMMATR;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Uncovering molecular mechanisms of active transcriptional repression.;2020-09-01;2022-08-31;;Animal development and homeostasis critically depend on the accurate regulation of gene expression, which includes the silencing of genes that should not be active. Silencing or repression of transcription is mediated by a specific class of transcription factors termed repressors that, typically via the recruitment of co-repressors, can dominantly suppress transcription, even in the presence of activating cues. While the importance of such “active repression” is emphasized by severe developmental defects and diseases like cancer that can result when repressors are mutated, how repressors function is not well understood. In particular, how repression is achieved mechanistically and whether all repressors can repress all activators has remained elusive. Here, I propose to study the functional properties of repressors and the mechanisms of active repression by an interdisciplinary approach that combines genome-wide experiments, targeted assays, and bioinformatics. Specifically, I will use high-throughput functional assays in combination with the Gal4/UAS system to systematically test whether transcriptional repressors can repress all active promoters and enhancers or only specific ones but not others. Further, I aim to uncover the mechanisms behind active repression by recruiting repressors to active promoters and enhancers in a rapidly inducible manner, using chemically-inducible-proximity, to then assess the changes to DNA accessibility, histone modifications, and Pol II activity. In addition, I will measure differential protein composition and PTMs at active genomic regions, before and during induced repression. These approaches should identify critical molecular events, proteins, or PTMs and allow me to test their causal involvement in repression. This project has the potential to greatly improve our mechanistic understanding of transcriptional repression, which despite its importance for gene expression, development and disease has remained poorly understood.;174167,04;174167,04;H2020-MSCA-IF-2018;/MSCA-IF-EF-ST;FORSCHUNGSINSTITUT FUR MOLEKULARE PATHOLOGIE GESELLSCHAFT MBH;AT;;;;1;0;0;1;0;0 222166;840119;GLORIOUS;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Digital Poetry in Today’s Russia: Canonisation and Translation;2019-10-01;2021-09-30;;GLORIOUS is an interdisciplinary study of online networks created by contemporary Russian poets that brings together poets, scholars and translators. The project will offer the first theoretical conceptualisation of such networks, introduce the most exciting new voices to an Anglophone audience through translation and narrow the distance between literary scholarship and translation practice with the help of a bespoke website.;202158,72;202158,72;H2020-MSCA-IF-2018;/MSCA-IF-EF-ST;UNIVERSITETET I TROMSOE - NORGES ARKTISKE UNIVERSITET;NO;;;;1;0;0;1;0;0 222228;840809;GANDALF;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Gamification and Datafication towards Learning Forecasting;2019-10-07;2021-10-06;;"A full 90% of all the data in the world has been produced over the last two years and the challenge of our society is to turn a world full of data into a data-driven world. Whereas the impressive progress in predictive analytics let us have insight on everything, our motivational resources are limited to learn and understand our reality. Today, gamification is regarded as a promising technique to improve motivational affordance in domains where people have difficulty of engagement such as data analytics and forecasting education. In this regard, the GANDALF project proposes the design of gamification and datafication solutions, which aims at improvement of learning outcomes in the context of forecasting course and demonstrate a world view based on facts. GANDALF aims to experimentally investigate gamification effects on educational process of a forecasting techniques’ course by addressing three novel objectives: (1) Design, implement and use a web-based, modular, educational platform in order to teach exploratory data analytics (module 1) and forecasting time series methods (module 2); (2) Investigate behavioural and psychological effects of individual affordances on learning exploratory analysis and promote fact-based world-view; (3) Examine behavioural and psychological outcomes in the context of a forecasting time series methods course. GANDALF employs controlled experimental research methods, with pre-, post-test design and forecasting problems to gain knowledge on the gamification effect on learning, user-experience and users’ forecasting accuracy based on their characteristics as well. GANDALF, along with its innovative points, contributes not only to civic understanding of data, but also to investigate how to effectively motivate users to explore data insights. In parallel, GANDALF advances my professional career and personal development in interdisciplinary field of teaching and learning methodologies for forecasting courses with gamification strategies.";190680,96;190680,96;H2020-MSCA-IF-2018;/MSCA-IF-EF-ST;TAMPEREEN KORKEAKOULUSAATIO SR;FI;;;;1;0;0;1;0;0 222443;844027;IFSSOC;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Coming together or doing it for themselves? The apparent paradox of social information and individuality in foraging;2020-09-01;2023-08-31;;Social interactions are fundamental for many ecological and evolutionary processes, including foraging. However, in many animals that use social information, a high degree of individuality in traits such as site and diet selection also exists. This represents an apparent paradox when sociality could potentially reduce individuality. Thus, it is unknown how these two processes interact to shape current and future foraging behaviour. For instance, can some animals become specialised in terms of social information use, or does group foraging erode individuality? This project will determine the interplay between the social and learned components of foraging, and levels of specialisation in habitat use and diet, across of range of seabirds in the Sulidae family (a morphologically constrained but geographically diverse group). State-of-the-art biologgers will be used to collect coupled video and GPS data to quantify the prevalence of group, solitary and commensal foraging in focal taxa representative of tropical and temperate environments, and link strategy to foraging success. State-space models, trained on coupled datasets, will be applied to long-term tracking data from nine Sulid species, to allow a family-scale comparison of specialisation. Through these focused analyses of individual foraging, this research action will enable predictions about the adaptive capabilities of populations to climate change, thus aligning with EU environmental priorities. The current skill set of the experienced researcher, together with a suite of newly acquired skills gained under tutelage of the strong supervisory partnership at host organisations, will make this timely research possible. This global, interdisciplinary project will result in high levels of knowledge exchange, foster international collaboration, and maximise the experienced researcher’s professional development, mobility and career potential, while addressing a fundamental question by combining two fields in bioscience.;295940,16;295940,16;H2020-MSCA-IF-2018;/MSCA-IF-GF;THE UNIVERSITY OF EXETER;UK;;;;1;0;0;1;0;0 222438;843872;WONDER;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Low-Bandgap Fused Ring Electron Acceptors towards High-Efficiency Organic Solar Cells;2019-06-01;2021-05-31;;"Organic solar cells (OSCs) based on fused ring electron acceptors (FREAs) attract significant attention recently and exhibit great potential to achieve high efficiency, due to the FREA’s merits of high absorption coefficients in visible region, easily tunable energy levels, relatively high electron mobility, and proper miscibility with donors for fine phase separation. Despite of the great advance in FREAs over the past few years, the power conversion efficiency (PCE) of FREA based OSCs is still lower than those of other solar cells so far. It is limited by two major problems: large bandgap of FREAs and large energy loss (Eloss) in devices. In this project, I aim to address these issues and develop high-efficiency OSCs from three aspects: 1) to develop novel FREAs with low bandgap, matching energy levels and high electron mobility via designing novel large fused ring donor units, 2) To reduce Eloss via adjusting and matching the energy levels of polymer donors and FREAs for high-efficiency OSCs, 3) to formulate key rules of designing FREAs to achieve low Eloss with high short-circuit current density (JSC) and fill factor (FF) via exploring the relationship between Eloss in OSCs and the intrinsic properties of FREAs. The expected outcomes of this project include new FREA materials and high-efficiency OSCs, as well as fundamental knowledge concerning Eloss in OSCs. In addition to the scientific achievements, the fellow will obtain new interdisciplinary knowledge and skills, and achieve professional maturity by training during the project. Successful implementation of this project will also promote the international competitiveness of the host organization in OSCs. Potential commercialization of the new FREA materials and OSC products will contribute to economic growth and afford new job opportunities for the European society.";203852,16;203852,16;H2020-MSCA-IF-2018;/MSCA-IF-EF-ST;LINKOPINGS UNIVERSITET;SE;;;;1;0;0;1;0;0 222374;842860;SocBehGenoPheno;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Genetic basis of emergent social behaviour from genotype-phenotype mapping;2019-07-01;2021-06-30;;Social behaviour plays an important role in the survival and development of many species with the most conspicuous and ubiquitous form being collective behaviour – the coordinated action of two or more individuals of the same species. Despite immense interest in collective behaviour in biology, the dynamic relationship between genotypes and phenotypes characterising this phenomenon remains opaque. Understanding this link, however, is crucial to elucidating the mechanisms of collective behaviour and emergence of social structures, and, most importantly, the genetic origins of social behaviour. In this project, I aim to quantify the genotype-phenotype mapping in the social behaviour of the nematode worm Caenorhabditis elegans using quantitative phenotyping and computational modelling. Due to its unique amenability to exhaustive genetic analyses, trackability and rich collective properties (so-called collective feeding), C. elegans is a perfect system to address this question. My project will use high-throughput imaging data of social feeding in hundreds of different C. elegans strains. I will develop a novel dynamic multi-state model based on worm postures and spatial positions, allowing to quantitatively describe nematode social behaviour in a worm density-dependent manner. My research programme will, for the first time, rigorously examine the phenotypic behavioural space in C. elegans and test its tolerance to mutations in a social context, hereby providing insights into the genetic basis of emergent social behaviour. Such a study is extremely timely as it will build on the brand-new nematode data collected at my host university using cutting-edge imaging and tracking techniques. This interdisciplinary project will provide significant amounts of training in modern quantitative and systems biology, including data analysis and modelling, as well as in research project management and networking, and thus be an ideal stepping stone to an independent scientific career.;224933,76;224933,76;H2020-MSCA-IF-2018;/MSCA-IF-EF-ST;IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE;UK;;;;1;0;0;1;0;0 222297;841754;SOOCCESS;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;SOciO-eConomiC failurE and aSpiration biaseS;2020-04-06;2023-04-05;;From early childhood, many poor children brought up in segregated communities observe socio-economic failures such as poor living conditions, liquidity constraints, extremely high unemployment and low education levels attained by adults. Enhancing their aspirations is believed to be a tool capable of breaking one of the poverty feedback loops: poverty has been identified as a cause of the failure to aspire to one’s own potential, and at the same time, low aspirations are among the potential causes of persistent poverty. Consequently, adolescents from areas of high deprivation are generally believed to have low aspirations, though, in fact, their aspirations vary considerably, and may be generally high. This signals two main aspiration biases: aspirations failure and aspirational gap. This project is aimed to investigate how stimulating success/failure environments can reduce aspiration biases of the segregated poor, which, according to theory, should increase their chances to escape the poverty trap. The project has an interdisciplinary character: it is aimed to investigate the psychological construct of aspirations in the economic context in educational environments. Using cutting-edge methods from behavioural and experimental economics, we will experimentally investigate to what extent exposure to success/failure environments will lead to a significant decrease/increase in aspirational biases. From the methodological perspective, we will first design a novel approach to the experimental elicitation of aspirations, then we will design an experiment manipulating success/failure to assess their effects on aspirations. From the empirical viewpoint, using experimental data, the project will shed new light on the relationship between socio-economic background and aspirational biases, and thus test the predictions of economic theory. To address the concern of external validity, the proposed experiments will be conducted in different cultural settings.;277940,16;277940,16;H2020-MSCA-IF-2018;/MSCA-IF-GF;UNIVERSITY OF DURHAM;UK;;;;1;0;0;1;0;0 222348;842402;Dielec2DBiomolecules;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Dielectric measurement of two-dimentionally confined biomolecules at the nanoscale;2019-06-03;2021-06-02;;Macromolecular organization and interactions have long been recognized to be strongly influenced by electrostatic and electrodynamics interactions which in turn depend on the molecular polarizability. In particular, molecular polarization plays a fundamental role in the molecular structure of biomolecules like DNA and proteins. Yet, this physical property of biomolecules has remained almost unexplored so far because measurements on the molecular scale are a technical challenge. Previous experimental work mostly relied on standard approaches as such broadband dielectric spectroscopy which are limited to the micrometer scale and, therefore, cannot resolve the polarization properties of single molecules. Hence, new experimental approaches are needed to measure the polarizability of molecules at molecular level. In this project, we will tackle this important issue and develop a novel experimental platform that will allow to access for the first time the polarizability of biomolecules under two-dimensional (2D) confinement. This will be achieved by coupling two novel technologies of nanoscience: scanning dielectric microscopy, a recently developed scanning probe technique, and the 2D-materials technology. We will engineer novel 2D liquid cells by assembling 2D crystals, and we will measure the dielectric properties of the biomolecules confined inside using a scanning probe. This is an ambitious experimental research with a strong interdisciplinary and groundbreaking nature, based on the powerful combination of new microscopic approaches with novel 2D materials. The developed platform will access previously unknown physical properties of biomolecules that are crucial to understand their behaviour. It will provide much-needed feedback for first-principles and mean-field theories and allow a better understanding of biomolecular structure and functions.;224933,76;224933,76;H2020-MSCA-IF-2018;/MSCA-IF-EF-ST;THE UNIVERSITY OF MANCHESTER;UK;;;;1;0;0;1;0;0 222310;841902;CausalBoost;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Using causal discovery algorithms to boost subseasonal to seasonal forecast skill of Mediterranean rainfall;2020-03-01;2022-02-28;;"The Mediterranean region (MED) is a hotspot of anthropogenic climate change and impacts are probably already felt today; recent heatwaves and persistent droughts have led to crop failures, wild fires and water shortages, causing large economic losses. Climate models robustly project further warming and drying of the region, putting it at risk of desertification. The particular vulnerability of this water-limited region to climatic changes has created an urgent need for reliable forecasts of rainfall on subseasonal to seasonal (S2S) timescales, i.e. 2 weeks up to a season ahead. This S2S time-range is particularly crucial, as the prediction lead time is long enough to implement adaptation measures, and short enough to be of immediate relevance for decision makers. However, predictions on lead-times beyond approximately 10 days fall into the so-called “weather-climate prediction gap”, with operational forecast models only providing marginal skill. The reasons for this are a range of fundamental challenges, including a limited causal understanding of the underlying sources of predictability. The proposed research effort aims to improve S2S forecasts of MED rainfall by taking an innovative, interdisciplinary approach that combines novel causal discovery algorithms from complex system science with operational forecast models. This will overcome current limitations of conventional statistical methods to identify relevant sources of predictability and to evaluate modelled teleconnection processes. The outcomes of this project will (i) identify key S2S drivers of MED rainfall, (ii) systematically evaluate them in forecast models, (iii) derive process-based bias corrections to (iv) boost forecast skill. My strong background in both causal inference techniques and atmospheric dynamics puts me in a unique position to lead this innovative effort and to achieve real progress in reducing the “weather-climate prediction gap” for the MED region.";212933,76;212933,76;H2020-MSCA-IF-2018;/MSCA-IF-EF-ST;THE UNIVERSITY OF READING;UK;;;;1;0;0;1;0;0 222084;838772;LADIE;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Investigation of nonlinear stimulated emission in optically excited dielectrics;2020-04-01;2022-03-31;;The nonlinear stimulated emission of ultraviolet light in a piece of optically excited – and thus metalized – glass that usually absorbs light is counterintuitive to what has been known for many decades about light-material interaction. However, this is exactly what was recently experimentally observed for the first time. Although a preliminary explanation and model describing the effect of laser amplification in excited dielectrics (LADIE) exists, a manifold of questions about fundamental processes like the universality, the potential of nonlinear light amplification and how giant-band-gap-renormalization in dielectrics works remain unanswered. In this project, a thorough investigation of the novel phenomenon and the associated rare nonlinear stimulated emission will be initiated. On the one hand, this study is based on femtosecond spectroscopy, deploying pump-probe experiments, utilizing light-conversion and pulse-shaping techniques that will be applied to a large variety of custom-made samples. On the other hand, the experimental studies will be complemented by advanced theoretical modelling of the material excitation that will be extended towards incorporating a proper description of the new mechanisms. The investigation of the LADIE effect will most likely open up an entirely new scientific field with many new surprises in store and the potential for novel derived applications. Its perspective is a revolution in laser technology, building high power nonlinear laser amplifiers in a huge variety of band-gap materials, which has a clear interdisciplinary aspect to semiconductor and optoelectronic research (i.e. telecommunication hardware), biophysics (cell surgery, nonlinear microscopy) and nonlinear optics in general.;207312;207312;H2020-MSCA-IF-2018;/MSCA-IF-EF-ST;AARHUS UNIVERSITET;DK;;;;1;0;0;1;0;0 222045;838183;BacDrug;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Bacterial membrane vesicles a novel delivery system for the treatment of multi-drug resistant Gram-negative bacterial infections.;2020-01-01;2021-12-31;;'Bacterial infections are a significant public health challenge and a major cause of human mortality globally. Antibiotics are indispensable for the treatment and prevention of infections caused by bacteria. However, global spread of drug-resistant bacteria, coupled with a dearth of new antibiotics in development has led to an alarming shortage of effective drugs. Gram-negative bacteria, in particular, protect themselves against antibiotics with a highly selective outer membrane. The high burden of diseases caused by Gram-negative bacteria, combined with their frequent multi-drug resistance has placed them as world´s highest-priority pathogens by the World Health Organization. Consequently, there is an urgent need for novel therapeutic approaches that combat Gram-negative bacterial pathogens. The goal of 'BacDrug' is to use lipid-based bacterial membrane vesicles (BMVs) produced by non-pathogenic Lactococcus lactis as delivery system. BMVs have great potential as nanocarriers to by-pass the outer membrane and deliver their toxic payload to kill drug-resistant Gram-negative pathogens. A range of strategies will be used to load BMVs with cargo, including genetic engineering of L. lactis as well as chemical treatments. This Fellowship will harness expertise and techniques across microbiology, molecular biology, nanotechnology and drug design to deliver a successful outcome. The collaborative, truly interdisciplinary, cross faculty setting within the groups of Prof Molly Stevens (materials and bioengineering) and Dr Andrew Edwards (molecular microbiology) at ICL combines world-class expertise and provides an environment to maximise the success of this Fellowship, both in terms of the delivering the project and the training opportunities provided. Moreover, this innovative, alternative strategy to tackle drug-resistant Gram-negative bacterial infections has a high translational potential, which will be exploited via the clinical and translational research clinics at ICL.';212933,76;212933,76;H2020-MSCA-IF-2018;/MSCA-IF-EF-ST;IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE;UK;;;;1;0;0;1;0;0 222076;838667;INTERACTION;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;resIlieNT EneRgy systems for climAte Change and susTaInable develOpmeNt;2019-08-15;2021-08-14;;A primary challenge in the near future is to accelerate improvements in human well-being as expressed in the Sustainable Development Goals (SDGs) and mitigate climate change, as required by the Paris Agreement. INTERACTION recognises that access to energy correlates with improved well-being, that climate change mitigation and adaptation require a rapid transition to sustainable, renewable energy sources, and that stakeholder engagement is key to the success of energy transformations. INTERACTION will bridge the gap between high-level modeling of energy systems and evaluation of solutions by working with scientific partners to develop energy-transition pathways, translate model results to realistic implementation strategies in least-developed partner countries through stakeholder workshops, and to provide regionally-specific feedback to the modelling community. Evaluation of results will lead the researcher to gain skills through on-site assessments and participatory engagement with stakeholders, focusing on the multi-dimensional development priorities and commitments made by governments to SDGs and climate change mitigation. An innovative and interdisciplinary process is proposed by INTERACTION, leveraging strong existing partnerships in selected countries to work with local actors, enabling consultation and discussion to develop alternative energy-system plans, while contributing to energy-system transformations and ensuring consistency between these plans and countries’ Nationally Determined Contributions to the Paris Agreement's, climate change adaptation strategies, and SDGs. This country-specific research will provide case studies relevant for other regions as well as fulfill the goal of the MSCA by enabling the researcher to diversify his expertise in energy systems from a theoretical and macro-level to implementation at an international level and in developing countries.;174806,4;174806,4;H2020-MSCA-IF-2018;/MSCA-IF-EF-ST;CLIMATE ANALYTICS GMBH;DE;;;;1;0;0;1;0;0 222069;838560;WoodSpec;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Rapid quality assessment of wood-based materials through spectroscopy;2019-12-01;2021-11-30;;"The European concern about climate change and greenhouse gas emissions has led to the promotion of clean energies. Considering the size of the waste wood market, the efficient utilization and the most appropriate exploitation of these materials could be a driver for climate change mitigation. In fact, it is well known that the reuse and recycle of waste materials is to be preferred to landfill. The wood materials could potentially be exploited in the panel industry to produce composites - such as panels - or they could be used for energy purposes instead of disposing them off. This project will develop a rapid tool based on spectroscopic techniques for the discrimination among the different types of wood-based materials – defining accordingly the most suitable target of use – and for assessing the chemical-physical characteristics (e.g. ash content, moisture content and calorific value) of the wood materials prior to be intended for energy purposes. The project takes an interdisciplinary approach involving a combination of analytical chemistry, chemometrics, spectroscopic techniques and wood science and it combines my research experience on wood sector with the host expertise in spectroscopic and chemometric techniques. The project will lead to important breakthroughs in the wood and wood-energy sectors since the expected results will support and valorize the wood-based materials in the optic of green economy and sustainable development. The project will enhance collaboration among scientific and non-scientific world promoting the application of the research. In addition, it will open up new collaborations thanks to the possibility to apply multivariate data analysis in different sectors beyond that of wood (i.e. food or waste). This project will be carried at Chemometrics and Analytical Technology Section of University of Copenhagen and at Biomass Lab of Universit? Politecnica delle Marche during a secondment.";207312;207312;H2020-MSCA-IF-2018;/MSCA-IF-EF-ST;KOBENHAVNS UNIVERSITET;DK;;;;1;0;0;1;0;0 221898;832713;SafeCEREAL;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Safe Copper Engineered for Release and Efficacy on Agricultural Land;2019-09-01;2021-08-31;;"The most recent scientific investigations in the field of sustainable nano-agrochemicals show that foliar application of copper nanoparticles (CuNPs) to plant leaves can be new strategy to reduce Cu deficiency in wheat, decrease Cu bulk emissions to the environment and reduce diseases (e.g. wheat leaf rust, tan spot, and Fusarium head blight) that are heavily affecting wheat production sector in the EU and globally. Therefore, resolving the environmental fate of CuNPs after foliar application will be an important step for their practical use. The goal of this Marie Sklodowska Curie Fellowship and SafeCEREAL project is to allow reliable assessment of environmental risks and benefits of using CuNPs in agriculture. Major research targets are to investigate the complex interactions between CuNPs and wheat after foliar application (WP1), gain further knowledge of the possible CuNPs’ interaction with soils under more realistic scenarios (WP2), and perform risk assessment of CuNPs’ release to groundwater by reproducing environmentally relevant release scenarios (WP3). The achievement of these goals requires a multidisciplinary approach including environmental nanotechnology and chemistry, plant physiology and applied geophysics – all of which are part of the research conducted at the University of Novi Sad Faculty of Sciences, Serbia, who will readily engage all its resources and mobilize its international partnerships. This fellowship will involve carefully planned public outreach activities and focus on a wide range of transferable and technical skills that will strengthen the Applicant, the Host, and the scientific community in the European Research Area and globally. Importantly, this project will lead to greater professional maturity of the Applicant by providing her the interdisciplinary expertise to design, lead and deliver future research projects; and identifying her as leading young scientist in the new area of research focused on realistic scenarios.";140021,76;140021,76;H2020-MSCA-IF-2018;/MSCA-IF-EF-ST;University of Novi Sad Faculty of Sciences;RS;;;;1;0;0;1;0;0 221914;833123;STAND4HERITAGE;SIGNED;H2020-EU.1.1.;ERC-2018-ADG;H2020;New STANDards for seismic assessment of built cultural HERITAGE;2019-09-01;2024-08-31;;"STAND4HERITAGE ambitiously engages in introducing new standards for safeguarding built cultural heritage for the next generations, which is a major societal demand. Due to its large diversity, the accurate description of the structural behaviour of heritage buildings is still an open issue, particularly when subjected to earthquake ground motions. Among the most frequently observed seismic damage mechanisms in these buildings, the out-of-plane of masonry walls is acknowledged as the main cause for building loss and injuries to people. There are many unresolved challenges to effectively assess the out-of-plane seismic behaviour of masonry structures. First, it is necessary to understand less known phenomena in masonry dynamics, which largely influence the out-of-plane behaviour and capacity of heritage buildings. A recent blind exercise to predict the capacity of a benchmark masonry structure to resist a dynamic excitation demonstrated that, although advanced simulation tools are available, leading international researchers are still unable to consistently provide a collapse estimate. STAND4HERITAGE will address the aspects for successful development of approaches for seismic response prediction of masonry structures, integrating the necessary stages for out-of-plane assessment. It will generate novel: integrated stochastic-based models to consider the seismic signal in the dynamic response and capacity; datasets of the dynamic response evaluated after an extensive shake table testing program; numerical approaches for simulation of the out-of-plane seismic behaviour; an integrated analytical approach for out-of-plane seismic assessment of heritage buildings. STAND4HERITAGE objectives are in line with the UN 2030 agenda for sustainable cities and communities. The project will be founded on the experience of the PI in the topic, and on the interdisciplinary expertise of his team in facing the challenges to provide optimal intervention solutions for heritage buildings.";2968755;2968755;ERC-2018-ADG;/ERC-ADG;UNIVERSIDADE DO MINHO;PT;;;;1;0;0;1;0;0 221989;836055;EMESAS;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Early Modern Exchanges in Sanskrit Astral Sciences;2019-11-01;2021-10-31;;"During the period of Mughal rule (1500 to 1800 CE) in early modern India, traditional Sanskrit astronomers actively engaged with Islamic (Ptolemaic) astronomy for the very first time. The EMESAS project proposes to study the canonical works (siddh?ntas) of three Sanskrit astronomers from the early 17th century: Nity?nanda, Mun?œvara, and Kamal?kara. The aim of this study is to find and analyse 'knowledge elements' found in their texts that are of Islamic origin, e.g., computational methods, geometrical arguments, astronomical models, diagrammatic proofs, etc. In doing so, the EMESAS project will contextualize the process of transmission, reception, assimilation, and adaptation of Islamic ideas in medieval Sanskrit astronomy. The Centre for the Study of Indian Science (CSIS), hosted by the Department of Cross-Cultural and Religious Studies at University of Copenhagen (UCPH), specializes in research on different aspects of Indian astral sciences like sa?hit? (omens), hor? (astrology), and ga?ita (mathematical astronomy). This makes CSIS ideally suited to host the EMESAS project. Under the supervision of Prof. Kenneth Zysk, the head of CSIS, the EMESAS project will examine Nity?nanda's 'Sarvasiddh?ntar?ja' (1639 CE), Mun?œvara’s 'Siddh?ntas?rvabhauma' (1646 CE), and Kamal?kara’s 'Siddh?ntatattvaviveka' (1658 CE). The research expertise at CSIS will enable this project to ask challenging questions: What motivated Sanskrit authors to discuss Islamic astronomical theories? What kind of technical explanations, mathematical vocabularies, and cultural tropes did Sanskrit authors adopt in accepting (or rejecting) foreign ideas? How did the scientific milieu of early 17th century Mughal India influence the development of Sanskrit astronomy? To answer these questions, the EMESAS project will develop a unique interdisciplinary approach that brings together philological, historical, and mathematical methods of analysis.";207312;207312;H2020-MSCA-IF-2018;/MSCA-IF-EF-ST;KOBENHAVNS UNIVERSITET;DK;;;;1;0;0;1;0;0 221927;833550;ACHROMAS;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Novel Materials Based on Alkali Chromites and Manganites for the Generation of Magnetic Skyrmions;2019-05-01;2021-04-30;;"The planned project explores a new class of frustrated magnets with the potential to host magnetic skyrmions. Skyrmions are nanoscale magnetic states and can be characterized as topologically protected spin vortices. They can be manipulated using low electric currents, thus can act as information bits in a new generation of energy efficient, ultradense memory and logic devices. Until now skyrmions have mainly been found in chiral magnets and at the surfaces of certain materials, but are often limited to a tiny pocket of the applied magnetic field versus temperature phase diagram. Furthermore, the skyrmions themselves in these systems are often of tens of nanometers or more in size, thus too large to be useful as information bits. Recent theoretical works have predicted that much more compact skyrmions might be found in frustrated magnets, and guidelines have been established to identify the most desirable structure features for hosting skyrmions. One group of materials that meet the structural criteria are the alkali chromites and manganites ABO2 (A = Na, K, Rb, Cs; B = Cr, Mn) and their derivatives, which are the focus of the proposed research. A comprehensive physicochemical investigation of the ABO2 family will be carried out, using cutting-edge methods of syntheses and modern analysis techniques for the determination of structure and composition. An investigation of their bulk magnetization and transport properties, combined with a study of their magnetic structures using Lorenz microscopy, neutron and resonant X-ray scattering, will enable magnetic phase diagrams to be mapped out and skyrmion phases to be identified and characterized. This interdisciplinary project involves close relationships between multiple related fields of science, such as solid state and magnetochemistry, theoretical physics and condensed matter physics, material science and nanotechnology.";187572,48;187572,48;H2020-MSCA-IF-2018;/MSCA-IF-EF-ST;RIJKSUNIVERSITEIT GRONINGEN;NL;;;;1;0;0;1;0;0 221866;818791;RICONTRANS;SIGNED;H2020-EU.1.1.;ERC-2018-COG;H2020;Visual Culture, Piety and Propaganda: Transfer and Reception of Russian Religious Art in the Balkans and the Eastern Mediterranean (16th to early 20th Century);2019-05-01;2024-04-30;;"The Russian religious artefacts (icons and ecclesiastical furnishings) held in museums, church or monastery collections in the Balkans and Eastern Mediterranean constitute a body of valuable monuments hitherto largely neglected by historians and historians of art. These objects acquire various interrelated religious/ideological, political and aesthetic meanings, value and uses. Their transfer and reception is a significant component of the larger process of transformation of the artistic language and visual culture in the region and its transition from medieval to modern idioms. It is at the same time a process reflecting the changing cultural and political relations between Russia and the Orthodox communities in the Ottoman Empire and its successor states in the Balkans over a long period of time (16th-20th century). In this dynamic transfer, piety, propaganda and visual culture appear intertwined in historically unexplored and theoretically provoking ways. The aim of RICONTRANS is to investigate, for the first time in a systematic and interdisciplinary way, this transnational phenomenon of artefact transfer and reception. Applying the cultural transfer approach in combination with the recent challenging openings of art history to visual studies, this project aims to: map the phenomenon in its long history by identifying preserved objects in the region; follow the paths and identify the mediums of this transfer; analyse the dynamics and the moving factors (religious, political, ideological) of this process during its various historical phases; study and classify these objects according to their iconographic and artistic particularities; inquire into the aesthetic, ideological, political, and social factors which shaped the context of the reception of Russian religious art objects in various social, cultural and religious environments; investigate the influence of these transferred artefacts on the visual culture of the host societies.";1914670;1914670;ERC-2018-COG;/ERC-COG;FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS;EL;BENAKI MUSEUM;EL;;1;0;0;1;0;0 221945;834385;FORMSofLABOUR;SIGNED;H2020-EU.1.1.;ERC-2018-ADG;H2020;Forms of Labour: Gender, Freedom and Experience of Work in the Preindustrial Economy;2019-09-01;2024-08-31;;The history of labour and its role in Europe’s preindustrial development has very largely been the history of adult men. FORMSofLABOUR seeks to put other workers in the picture, particularly women and servants, not simply by ‘adding them on’ but by showing how a full understanding of women’s work and of service offers a radical critique of existing approaches to work and to the idea of free labour. It focuses on England in the period 1300-1700 viewed in a comparative Western European perspective, and addressed these issues through three themes. (1) A revolutionary research technique which collects evidence of work tasks from court records to simulate a time-use study is used to explore the experience of work. This technique allows the work activities of women and men, young and old, employees and family members to be illuminated, with evidence of tasks, location and timing of work, creating an entirely new perspective on England’s early modern economy. (2) The theoretical underpinnings of the history of women’s work in the preindustrial economy are explored, reassessing key debates using interdisciplinary perspectives from economics and political science, as well as new archival evidence from themes 1 and 3. Gendered work patterns are viewed through the lens of freedom, rather than patriarchy, to create a step-change in our understanding of gender and work. (3) The issue of the extent to which labour was ‘free’ after the end of serfdom is interrogated through a careful examination of the range of forms of labour and the nature of labour laws, using a variety of archival evidence combined with a comparisons with serfdom and slavery, and the adoption of insights from development economics and anthropology. Together these interlocking themes create a new history of work in the economy which formed the background to grand narratives of Smith and Marx, arguing that with women and servants had been in picture, the story of economic development is transformed.;1666565;1666565;ERC-2018-ADG;/ERC-ADG;THE UNIVERSITY OF EXETER;UK;UNIVERSITY OF BRISTOL;UK;;1;0;0;1;0;0 222065;838529;ARCTICO;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Uncovering the Magnitude of Arctic Climate Change;2019-08-01;2020-08-31;;A key challenge in climate change science is to provide informed constraints on the magnitude of future climate change. Uncertainties associated with such predictions remain large due to the shortness of our observational records (at best 150 years) and the absence of large climate shifts therein to serve as an analogue for future change. This is especially problematic when estimating Arctic climate change because the response in the Arctic is amplified relative to the global mean, making the Arctic the most sensitive and vulnerable environment with regards to global warming. Efforts to assess the magnitude of past (e.g. pre-industrial) climate changes using climate proxies are thus crucial to further our understanding of how the Arctic system will respond to continued global warming. The proposed investigation seeks to constrain the magnitude of Arctic amplification by quantifying the influence of the carbonate ion concentration of sea water on the temperature signal recorded in the Arctic planktonic foraminifera Neogloboquadrina pachyderma sinistral (NPS). Using NPS shells collected from stratified plankton samples, I will combine established and new analytical techniques in trace element and isotope geochemistry to derive and isolate carbonate system parameters from the climate signature recorded in NPS. This approach is innovative and interdisciplinary as it takes advantage of cutting edge knowledge in proxy development without compromising on the benefit of a seasonally and spatially constraint dataset. This will provide a holistic understanding of how changing hydrological and other environmental conditions impact not only NPS lifecycle but also the geochemical signal recorded in their shell. Given the uncertainties associated with available paleoceanographic tools this will provide a major advancement in the field of paleoceanography and climate change science.;94686,8;94686,8;H2020-MSCA-IF-2018;/MSCA-IF-EF-ST;UNIVERSITAET BREMEN;DE;;;;1;0;0;1;0;0 222067;838525;SYMBIO-INC;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Mechanisms of symbiotic incompatibility in the arbuscular mycorrhizal association;2020-09-01;2022-08-31;;Understanding the mechanisms that control symbiotic incompatibility is fundamental to evaluate biological factors that delimit symbiosis on Earth and could help us to improve symbioses for practical applications. In terrestrial ecosystems, about 29% of vascular plants, including the plant model Arabidopsis, apparently lost or suppress their ability to host symbiosis with the arbuscular mycorrhizal (AM) fungi, one of the most ancient and functionally important symbiosis on Earth. Yet, the molecular mechanisms that control this symbiotic incompatibility are largely obscure, which is limiting our ability to consistently predict the conditions that constrain AM symbiosis and to engineer new symbiotic partnerships. SYMBIO-INC addresses the challenging question of what are the key molecular constraints that prevent AM fungi from developing functional associations with land plants. Unlike traditional approaches, SYMBIO-INC will employ an interdisciplinary strategy focused on direct evidence with unprecedented emphasis on fungal traits during interactions with Arabidopsis plants differing in hosting phenotypes. Genotypic and molecular aspects will be evaluated for their potential to control Arabidopsis susceptibility to fungal colonization. The hypothesis that fungal nutrition is critical during incompatible interactions will be tested here for the first time. Finally, powerful transcriptomic tools will be employed to deliver a holistic overview of fungal molecular responses under different degrees of compromised symbiotic development. This horizon-broadening approach, combined with the maturity of our knowledge in the topic, supported by a robust set of new preliminary data, makes the proposed research a timely opportunity for paradigm shifting and high impact. Finally, SYMBIO-INC will allow the researcher to reinforce and further expand skills and expertise, create new collaborations, and forge a successful career aiming at a future tenure-track position.;166320;166320;H2020-MSCA-IF-2018;/MSCA-IF-EF-ST;UNIVERSITE CATHOLIQUE DE LOUVAIN;BE;;;;1;0;0;1;0;0 221952;834610;MechaPattern;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Coordination between cell identity, tissue mechanics and proportionate patterning during vertebrate eye formation;2019-04-01;2021-03-31;;The development of an organ requires the precise coordination between pattern formation, morphogenetic movements and the final size of the system. Significant progress has been made in understanding these processes independently. The aim of this proposal is to integrate this information by analyzing coordination hubs, such as the crosstalk between YAP/TAZ and Wnt?-catenin pathways during the specification of the identity and the mechanical properties of the cell. I will use the development of the vertebrate eye as a defined paradigm. To identify intrinsic and relevant properties of this system, the two most powerful and amenable models of eye morphogenesis will be analyzed: the self-generation of 3D optic cups from mouse Embryonic Stem Cells and the in vivo development of the teleost eye. The plan is to generate a spatiotemporal activation map of the main determinants of eye identity and use them to link morphogen signaling with key morphogenetic processes in specific cells. This will be the groundwork to identify the role of retinal pigmented epithelial (RPE) cells during optic cup folding, the context that I will use to understand both the coordination between morphogen patterning (Wnt) and mechanical properties (Yap) of the retinal precursors, and between proportionated patterning and eye size (scale-invariant mechanisms). This proposal relies on the collaboration of multiple experts from the host institute and on the use of already developed bona fide protocols, reporter lines and signaling perturbations experiments, but revisited with cutting-edge technologies, such as light sheet microscopy and computational modeling. Thus, it is an extremely innovative but feasible project to understand deep-root questions of organ formation. Moreover, this interdisciplinary project will open unprecedented opportunities in the field of organ regeneration from a comprehensive morphogenetic perspective, which will be the foundation of my future independent research.;160932,48;160932,48;H2020-MSCA-IF-2018;/MSCA-IF-EF-ST;AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS;ES;;;;1;0;0;1;0;0 222062;838494;MagnetoVirology;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Diamond Magnetometry: A Versatile Tool for Virology and Medicine;2019-07-01;2021-06-30;;Reactive Oxygen Species (ROS)/ free radicals (FR) in cells have a very complicated role in viral infections. While some researchers point toward their usefulness in mediating viral infections, others conclude the exact opposite and claim that there are detrimental effects. To probe deeper into virus pathogenesis and improve anti-viral therapy, cellular FR - viral infection kinetics which potentially depends on virus, cell/animal model, type of reactive species, etc. needs to be investigated with high spatiotemporal resolution. However, all the traditional methods capable of detecting FR have limitations when real-time, long-duration, high resolution measurements are to be conducted within a small sample volume (inside of a cell). Recently, diamond magnetometry was proposed to study cellular FR with unparalleled sensitivity, resolution, and the possibility of real-time long-duration measurements. In this highly interdisciplinary collaborative research, I aim to establish this technique in studying cellular FR- viral infections kinetics. As a model system I will investigate the host cell FR response upon Sindbis virus (SINV) infection with high spatiotemporal resolution. FR response will be quantified via measuring T1 relaxation time of Nitrogen Vacancy centers in fluorescent nanodiamonds (FNDs). Furthermore, I intend to highlight the potential of diamond magnetometry in clinical diagnostics and drug development by demonstrating the FR detection in synovial fluid of arthritis patients (outcome of SINV infection) and detecting cells’ FR response to anti- oxidants. Upon successful completion, I will not only have elucidated the interplay of FR and SINV infections but also underscored the potential of diamond magnetometry in fundamental virology, infection biology, clinical diagnostics and pharmaceutical industry. This research strongly aligns with two work programs within Horizon 2020 focused on health (SC1-BHC) and nanotechnology- biotechnology (DT-NMBP).;187572,48;187572,48;H2020-MSCA-IF-2018;/MSCA-IF-EF-ST;ACADEMISCH ZIEKENHUIS GRONINGEN;NL;;;;1;0;0;1;0;0 221899;832697;BALANCE;SIGNED;H2020-EU.1.1.;ERC-2018-ADG;H2020;Mapping Dispersion Spectroscopically in Large Gas-Phase Molecular Ions;2019-05-01;2024-04-30;;We use IR spectroscopy of trapped ions in a cryogenic FT-ICR spectrometer to probe non-covalent, “dispersion” interactions in large, gas-phase molecular ions. We will measure conformational equilibria by N-H frequency shifts, and correlate gas-phase IR frequency to the N-H-N bond angle in an ionic H-bond. Substituents on “onium” cations can adopt various conformations, whose energies map interaction potentials. Substituents on their proton-bound dimers interact non-covalently through dispersion forces, whose quantitative evaluation in large molecules has remained difficult despite dispersion becoming increasingly cited as a design principle in the construction of catalysts and materials. The non-covalent interactions bend the N-H-N bond, leading to large shifts in the IR frequency. The proton-bound dimer acts like a molecular balance where the non-covalent interaction, is set against the bending potential in an ionic hydrogen bond. Despite encouragingly accurate calculations for small molecules, experimental benchmarks for large molecules in the gas phase remain scarce, and there is evidence that the good results for small molecules may not extrapolate reliably to large molecules. The present proposal introduces a new experimental probe of non-covalent interactions, providing a sensitive test of the diverging results coming from various computational methods and other experiments. The experiment must be done on isolated molecules in the gas phase, as previous work has shown that solvation substantially cancels out the attractive potential. Accordingly, the proposed experimental design, which involves a custom-built spectrometer, newly available tunable IR sources, chemical synthesis of custom substrates, and quantum calculations up to coupled-cluster levels of theory, showcases how an interdisciplinary approach combining physical and organic chemistry can solve a fundamental problem that impacts how we understand steric effects in organic chemistry.;2446125;2446125;ERC-2018-ADG;/ERC-ADG;EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH;CH;;;;1;0;0;1;0;0 221984;835939;VOLCPRO;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Volcanic Forcing in Climate Model Projections: Towards a New Paradigm.;2020-02-01;2022-01-31;;"Volcanic eruptions injecting gases into the stratosphere modify Earth’s radiative balance and atmosphere chemistry, which in turn impacts all components of the Earth system. The surface cooling that follows large eruptions can have major societal impacts and volcanic eruptions contribute to mitigate global warming. Yet, climate model projections use simplistic representation of this key forcing and commonly assume a constant volcanic forcing in the future. The most realistic projections only represent very large and rare eruptions, and ignore how climate change will affect the rise of volcanic plumes, the evolution of the associated aerosol clouds and the subsequent climate impacts. To improve the representation of volcanic forcing in climate model projections, I will address two fundamental questions: 1) How does a statistically realistic representation of volcanic eruptions of all magnitude in climate models affect projected climate changes? 2) How will climate-volcano feedbacks modulate the impact of future volcanic eruptions on climate? To answer them, I will perform a suite of experiments with the United Kingdom’s flagship Earth system model, UKESM1, which is a fully coupled aerosol-chemistry-climate model. These experiments are aimed to feed the designing of future climate projections. During the fellowship, I will gain brand-new skills in climate modeling and be trained by world-leading experts in this field. I will combine these skills with my expertise in physical volcanology to address the proposed research questions and, in particular, improve our understanding of climate-volcano interactions in the context of global climate change. The fellowship will enable me to become an interdisciplinary leader in climate-volcano research and will constitute a stepping stone towards new research opportunities and applications for a tenure-track position.";224933,76;224933,76;H2020-MSCA-IF-2018;/MSCA-IF-EF-ST;THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;UK;;;;1;0;0;1;0;0 221862;817577;HONORLOGIC;SIGNED;H2020-EU.1.1.;ERC-2018-COG;H2020;The Cultural Logic of Honor and Social Interaction: A Cross-Cultural Comparison;2019-09-01;2024-08-31;;"Understanding (un)willingness to coordinate with others, to compromise when faced with different choices, or to apologize for transgressions is crucial as these behaviors can act as strong facilitators or inhibitors of important interpersonal processes such as negotiations and coalition building. These behaviors play a major role when individuals from different cultural backgrounds work together to solve disputes or address joint challenges. Yet, we know little about what these behaviors mean in different cultural groups or how they are approached. With HONORLOGIC, I aim to initiate a step-change in our understanding of cultural variation in these important domains of social behavior by providing unique, multimethod, comparative and converging evidence from a wide range of cultural groups. I will answer the question “How do cultural groups that promote honor as a core cultural value approach coordinating with others, reaching compromise, and offering apologies?” by integrating insights from social/cultural psychology, behavioral economics, and anthropology. I will do this by collecting quantitative data using economic games, experiments, and surveys from Spain, Italy, Greece, Turkey, Cyprus, Lebanon, Egypt and Tunisia, as cultural groups where honor has been shown to play a defining role in individuals’ social worlds. I will also run the proposed studies in the US, the UK, Japan and Korea to provide a broader comparative perspective. HONORLOGIC will produce transformative evidence for theories of social interaction and decision making in psychology, economics, and evolutionary science by (a) producing innovative theory and data with an interdisciplinary and multi-method approach, (b) increasing the diversity of the existing evidence pool, (c) testing established theoretical assumptions in new cultural groups, and (d) contributing to capacity building in under-researched cultural groups in psychological research.";1998693,75;1998693,75;ERC-2018-COG;/ERC-COG;UNIVERSITY OF KENT;UK;THE UNIVERSITY OF SUSSEX;UK;;1;0;0;1;0;0 222009;836958;MCFPAD-3DSLs;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Multi-core fibre passive and active devices: 3D shape sensors and laser sources;2020-03-01;2022-02-28;;"'The key research goal of this project on 'Multi-core fibre passive and active devices: 3D shape sensors and laser sources' (MCF3DSLs) is to train a talented researcher on the development of passive and active devices and systems in high capacity multi-core fibres (MCFs) for application in 3D shape sensing and laser source emission. In the aspect of passive MCF devices, the proposed project will use spun MCFs to develop a new 3D shape sensor with a high reconstruction accuracy of millimetre even sub-millimetre. In the aspect of active deceives, this project will implant the well designed fibre MCF gratings in the active MCFs to develop a promising MCF lasers sources for the spatial division multiplexing communication systems. The success of this interdisciplinary project will provide a platform to extend photonics technology from present single-core to new emerging high capacity multi-core, a big step forward to increase the critical bandwidth and functionality for potential applications in optical-fibre communications, medical diagnosis and treatment systems, civil engineering structure monitoring, and security and defense systems. The Fellow - Dr Guolu Yin will be trained at the host, Aston University, UK, and other four academic/industry partners at EU. The hosts will provide scientific training in fibre optic devices, optical sensors, fibre lasers, and advanced grating modelling to enable the fellow to become a leader in an area of high practical relevance. Additionally, the fellow will be trained to improve his complementary-skills, ensuring that he is equipped to be a future leader in academia. The project outputs will contribute to European leadership in photonics and will produce a new generation of photonic systems and devices in the challenging multi-core fibre instead of the conventional single mode fibre, which support the European Union's vision for a high-technology economy to promote European social and economic cohesion and prosperity.'";224933,76;224933,76;H2020-MSCA-IF-2018;/MSCA-IF-EF-ST;ASTON UNIVERSITY;UK;;;;1;0;0;1;0;0 221930;833401;NEXUS-DRR;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Building resilience in the face of nexus threats: local knowledge and social practices of Brazilian youth;2019-08-01;2022-07-31;;The complex interactions of the food-water-energy nexus have become prominent in academic and policy discourse addressing issues of resource security, equitable access, and resource interdependencies. The nexus has gained particular importance in terms of vulnerability to natural hazards since these can negatively affect the long-term availability of resources and pose a major risk to resource security. Building long-term resilience to resource insecurity requires interconnected solutions that also take account of particularly vulnerable groups such as youth. NEXUS-DRR offers a novel and interconnected approach by linking nexus thinking with disaster risk reduction. This MSCGF investigates threats to the food-water-energy nexus from the perspective of local knowledge and social practices of Brazilian youth in marginalized communities that are affected by environmental hazards such as floods and landslides. Using participatory research methods such as citizen science, it explores young people’s everyday lived experiences and practices related to the nexus. It investigates their understanding of the nexus, their access to and their use of resources as well as their knowledge of the causes of nexus threats and future scenarios. Moreover, it explores the social practices that young people have adopted to reduce their vulnerability in terms of resource insecurity, and investigates how youth knowledge and their social practices can be valued for the development of public policies. Through joint supervision, mentoring, career and interdisciplinary skills development at the beneficiary, the University of Birmingham (UK), and the host university, the University of Sao Paulo (Brazil), this MSCGF significantly strengthens the Fellow’s profile and career opportunities as an internationally recognised researcher of excellence in applied nexus, resilience, and environmental youth research.;270327,36;270327,36;H2020-MSCA-IF-2018;/MSCA-IF-GF;THE UNIVERSITY OF BIRMINGHAM;UK;;;;1;0;0;1;0;0 222015;837724;D-FINED;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Duality for Finite Models: Relating Structure and Power;2020-01-01;2021-12-31;;"'The present project is positioned in the research area of logic and semantics of computation, combining a rich mathematical theory with concrete applications in computer science. Finite model theory (FMT) is the specialisation of model theory to the class of finite models, and has been called ``the logic of computer science' because in the latter field the basic models of computation are finite. Most of the classical results of model theory fail when restricted to finite models, hence FMT is studied using different tools and methods. For this reason, FMT has developed mostly independently from model theory and the research communities, as well as the techniques, are almost disjoint. FMT exemplifies a strand in the field of logic in computer science focussing on expressiveness and complexity (``Power'), as opposed to the one focussing on semantics and compositionality (``Structure'). In this project we will apply Stone duality to bridge the gap between the semantics methods of model theory, and the combinatorial and complexity-theoretic methods of FMT, i.e., to relate Structure and Power. In his Ph.D. thesis, the applicant has successfully applied Stone duality and topology to the study of formal languages and logic on finite words. The proposed project constitutes both a natural continuation of this research line, generalising from finite words to finite models, and a novel approach to FMT. The applicant will collaborate with the supervisor, who is a leading expert in the interactions between logic and computational models arising in computer science. An essential feature of this project is its high degree of interdisciplinarity, aiming to strengthen the connections between mathematics and computer science. The host institution, which is home to several experts in logic and foundations of computer science, will benefit from the applicant's experience in duality theory and topology, thus fostering cross-fertilisation within the European research community.'";212933,76;212933,76;H2020-MSCA-IF-2018;/MSCA-IF-EF-ST;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;UK;;;;1;0;0;1;0;0 221957;834493;OSeaIce;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Two-way interactions between ocean heat transport and Arctic sea ice;2019-11-01;2020-10-31;;Sea ice in the Arctic region is retreating at fast pace with potential impacts on the weather and climate at mid and high latitudes, as well as the biosphere and society. Sea-ice loss is driven by anthropogenic global warming, atmospheric circulation changes, climate feedbacks, and ocean heat transport. To date, no clear consensus regarding the detailed impact of the latter (ocean heat transport) on Arctic sea ice exists. Conversely, the changing sea ice also affects ocean heat transport, but this effect is much less studied. Therefore, this action proposes to explore the two-way interactions between ocean heat transport and Arctic sea ice. To this end, we will use a state-of-the-art global climate model (EC-Earth) and perform different sensitivity experiments to gain insights into these important interactions. Based on the results from these experiments, we will refine model projections of Arctic sea ice. Comparison to observations will be carried out to ensure that model simulations are realistic. We will also assess the impact of model spatial resolution on the relationships between ocean heat transport and Arctic sea ice, as an extension of the work performed within the EU PRIMAVERA project (PRocess-based climate sIMulation: AdVances in high resolution modelling and European climate Risk Assessment). This action will allow to provide more reliable and robust information on regional Arctic sea-ice present and future changes to users and stakeholders. Finally, this project is highly interdisciplinary as it combines three key components of the climate system (i.e. the ocean, sea ice, and atmosphere), and will be done in collaboration with the NordForsk ARCPATH project (Arctic Climate Predictions: Pathways to Resilient, Sustainable Societies), which focuses on improving Arctic climate predictions and better understanding socio-economic impacts of Arctic changes.;101926,08;101926,08;H2020-MSCA-IF-2018;/MSCA-IF-EF-SE;SVERIGES METEOROLOGISKA OCH HYDROLOGISKA INSTITUT;SE;;;;1;0;0;1;0;0 221961;834811;NANOZID;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;DNA nanohydrogel loaded Liposomal formulations for high loading efficiency of antimicrobial drugs against intracellular bacterial and topical biofilm infections;2019-05-15;2021-05-14;;Dr. Sybil Obuobi was awarded her PhD in Pharmacy at the National University of Singapore (Singapore) in July 2018 and is very excited to pursue a postdoctoral fellowship at the University of Tromso The Arctic University of Norway (UiT, Norway) under the supervision of Prof. Natasa Skalko-Basnet, a renowned expert in advanced drug delivery. Their project will exploit DNA nanohydrogels, as a novel universal platform to improve the loading efficiency of antimicrobials in mannosylated liposomes against intracellular and topical biofilm infections. This approach fills the current research gap for high drug loading innovative systems in nanomedicine and holds great promise to improve drug efficacy against difficult-to-reach pathogens thus, there is immense potential for new patentable technologies/products. This area of research will advance knowledge in antimicrobial drug delivery and the outcomes will appeal to formulation scientists, R&D scientists and people with persistent skin infections that impose significant economic challenge and contribute to the spread of antimicrobial resistance. With access to state-of-the-art equipment and interdisciplinary environment within the participating organisations (UiT, University of Helsinki and BIOTEC Pharmacon ASA) and administrative support, Dr. Obuobi will acquire new skills in life sciences, expertise in state-of the art biofilm models, hands-on teaching experience, transferrable skills in grant/patent applications and project management alongside new knowledge in product development. Against the backdrop of her notable achievements as a young scientist, she has the capacity to attain research growth through this fellowship and will seize this opportunity to diversify her competency, improve her record of publications, gain independence, build new international networks and apply for an ERC-StG grant- outputs that are expected benchmarks for academic appointments and essential to launch her career within Norway/Scandinavia.;214158,72;214158,72;H2020-MSCA-IF-2018;/MSCA-IF-EF-ST;UNIVERSITETET I TROMSOE - NORGES ARKTISKE UNIVERSITET;NO;;;;1;0;0;1;0;0 222071;838658;ItalianWoolf;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Virginia Woolf and Italian Readers;2019-09-01;2021-08-31;;"This project examines the reception of Virginia Woolf in Italy and it will lead to the first multi-media comprehensive study of her reception in Italian culture. Employing an archive-based interdisciplinary approach drawing on reception studies, periodical studies, publishing history, the project will trace the waves of her reception, from Fascism to the present. To do so, it will examine the key stages of Woolf’s reception in relation to the political, cultural and institutional factors that influenced publishers and translators over the years and it will map out the publishers, translators, and cultural gate-keepers that patronised Woolf’s works in the Italian context. The project will focus on the censorship mechanisms put in place by Fascism and how Woolf translators challenged them; the circulation of Woolf works in the post-war Neorealist phase; the role her work played in the rise of the Italian feminist movements in the 1970s; and finally how, since the late 1990s, the reception of the transmedial adaptations of her work consolidated Woolf as a cultural icon in Italy. In addition to traditional scholarly outputs, this project will create a digital open-access database which will serve as a research tool for scholars, students and the lay public. Woolf’s work will be considered a litmus test for key moments of change in the Italian cultural industry. The study of Woolf’s Italian reception will, in turn, contribute to the growing scholarly interest in the reception of Anglophone Modernist writers in European literary marketplaces by embracing the recent calls to globalise the reach of Anglophone modernism and by affirming how peripheral and context-specific concerns help to reconsider the adaptability of modernist innovations and to question the idea that transfers occur in a friction-less cultural vacuum. To this end, the Italian case will offer substantive methodological concerns and empirical evidence to rethink the framework of global modernism studies.";224933,76;224933,76;H2020-MSCA-IF-2018;/MSCA-IF-EF-ST;THE UNIVERSITY OF READING;UK;;;;1;0;0;1;0;0 222061;838445;INFINITY;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Infinity in Mathematics: A Philosophical analysis of Critical Views of Infinity;2019-07-01;2021-06-30;;"This project’s research goal is a systematic philosophical and mathematical analysis of critical views of infinity: views which have questioned one or more aspects of standard approaches to infinity in mathematics. Criticism of infinity originates in fundamental debates at the turn of the 20th century and re-emerges in contemporary mathematics under the stimulus of computer applications. The project’s first aim is to develop a novel rigorous examination of what is objected to infinity and why. The next goal is a philosophical and mathematical analysis of this criticism and of strategies proposed to overcome the perceived problematic nature of the infinite. To achieve these goals, the ER will integrate precise philosophical inquiry with state of the art knowledge of contemporary mathematics. She will analyse the early 20th century texts and compare that criticism of infinity with the one which emerges in contemporary mathematics; she will use a range of logical tools to sharpen and analyse the fundamental concepts of this debate. The ER has the ideal profile to initiate, with the support of the host institution, an interdisciplinary analysis of the mathematical infinite, as she is simultaneously a mathematician and a philosopher, with years-long experience in logic. The Department of Philosophy at the University of Oslo is the perfect research environment for carrying out this project: the supervisor, Professor ?ystein Linnebo, is leading figure in EU’s philosophy of mathematics and this project is very well aligned with his group’s research interests. Through a programme of training through research, the ER will strengthen her philosophical readership, broaden her range of competences, forge new connections to the philosophical community and gain skills in dissemination and communication. This project will be an important point of departure for her future academic career, proposing her as unique bridge between the EU’s philosophical and mathematical communities.";214158,72;214158,72;H2020-MSCA-IF-2018;/MSCA-IF-EF-ST;UNIVERSITETET I OSLO;NO;;;;1;0;0;1;0;0 222072;838602;ProResA;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;The time course of pronoun resolution in post-stroke and progressive aphasia;2020-02-01;2023-01-31;;"European populations are aging, and aging individuals are more vulnerable to neurological diseases which often result in language impairments (i.e. aphasia). These impairments render the skilled communication needed for successful everyday living impossible, with impact on mental health, quality of life and career burden. Although language impairments in aphasia have been studied, aphasic individuals' sentence interpretation in time-sensitive measurements including the time course and source of their brain responses have only scarcely been examined. This action seeks to generate scientific knowledge on primary progressive aphasia (PPA, a form of aphasia resulting from progressive brain degeneration) and post-stroke aphasia by investigating the time course of how people with aphasia precisely work out to whom a pronoun (e.g. her/herself) refers during moment-by-moment on-line sentence processing. This action aims to fill this important gap by answering the following research questions: (i) Does pronoun processing become impaired in PPA as the disease progresses, and if so how? (ii) How is pronoun processing modulated in the brain with respect to its moment-by-moment time course and locations of brain responses in aphasia and unimpaired individuals? (iii) Is pronoun processing impaired in aphasia in typologically different languages (i.e. Dutch, French and Turkish)? (iv) What are the factors influencing pronoun processing difficulty in aphasia? Findings of this interdisciplinary action will inform both the theories of language breakdown in aphasia and clinical assessment of sentence-level processing in the aphasia types with direct implications for treatment of these debilitating disorders. Importantly, when this action is complete, an eye-movement / machine learning database of aphasic processing, which can potentially be used to determine early sensitive markers of (primary progressive) aphasia, will be made publicly available for future research re-use.";277259,52;277259,52;H2020-MSCA-IF-2018;/MSCA-IF-GF;RIJKSUNIVERSITEIT GRONINGEN;NL;;;;1;0;0;1;0;0 222041;838143;ReSOLeS;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;New Reconfigurable Spectrum Optical Fibre Laser Sources;2019-05-01;2021-04-30;;Optical lasers are extraordinary light sources that have revolutionized human lives. These are crucial for optical fibre sensor (OFS) interrogation systems. Thus, the characteristics of each source are strongly connected to its sensor system. In large monitoring systems, different OFS are multiplexed in the same optical network. Hence, it exists an increasing necessity of new and special light sources for the new networking requirements. The project aims to develop a revolutionary laser system for high performance remote multiplexing sensor networks for Sustainable Development and Smart Cities applications. The project “ReSOLeS” mainly focus on the research and development of a novel reconfigurable spectrum optical fiber laser source. It is based on the random distributed feedback (RDFB) effect. The modeless characteristic of RDFB lasers allows controlling the emitted frequencies by the internal modulation of the distributed laser cavity, which the applicant first demonstrated. To date, laser spectrum were modified only by filtering the cavity. In this project, we propose an innovative approach that uses a modulating signal to control the output spectrum. This enable higher spectral flexibility and reconfigurability speed than the traditional filtered laser cavities. To make it possible, first, we will develop a model of the system and that will be implemented by software. Next, the system will be experimentally demonstrated and two system enhancements will be tested. Finally, it will be validated in high performance optical fiber sensor networks for Smart Cities applications. This interdisciplinary project will combine the fellow’s expertise in RDFB lasers with the world-leading expertise of the host’s Smart Cities Institute in fiber lasers, OFSs and Smart Cities. In addition, “ReSOLeS” will benefit from the host’s well-established partnerships in academia and industry, and from the training and mentoring opportunities for the fellow's career development.;172932,48;172932,48;H2020-MSCA-IF-2018;/MSCA-IF-EF-ST;UNIVERSIDAD PUBLICA DE NAVARRA;ES;;;;1;0;0;1;0;0 218416;813124;ECORISK2050;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2018;H2020;Effects of global change on the emission, fate, effects and risks of chemicals in aquatic ecosystems;2018-10-10;2022-10-09;;"By 2050, the world population will reach nine billion people and three quarters of the global population will live in cities. The development path to 2050 will be marked by shifts in land-use and weather patterns, and by changes in the way water and food resources are obtained and managed all over the world. These global changes (GCs) will affect the emissions, environmental transport pathways and fate of chemicals, and thus affect the exposure of the natural environment to chemicals. Future changes may also alter the sensitivity of ecosystems to chemical exposure. Therefore, the ECORISK2050 project brings together a world leading and interdisciplinary consortium of universities, research institutes, industry and regulatory and governmental authorities to deliver a cohort of Early Stage Researchers (ESRs). The coupled training goals and research objectives of the project are: (1) to assess how the inputs of chemicals from agriculture and urban environments and their fate and transport are affected by different environmental conditions, including those of specific EU regions, and how this will change under GC scenarios in order to assess the likely increase in chemical risks to human and ecosystem health; (2) to identify potential adaptation and mitigation strategies that can be implemented in the short and medium term, to abate unacceptable changes in risks, and use the GC scenarios to propose robust implementation pathways, and (3) to develop a set of tools for use by industry and policy makers, that allow the impacts of a range of GC-related drivers on chemicals risks to be assessed and managed. The project will deliver the next generation of scientists, consultants and industry and governmental decision-makers who have the knowledge and skill sets required to address the changing pressures that chemicals emitted by agricultural and urban activities pose to aquatic systems on the path to 2050 and beyond.";3596088,24;3596088,24;H2020-MSCA-ITN-2018;/MSCA-ITN-ETN;WAGENINGEN UNIVERSITY;NL;"FUNDACION IMDEA AGUA;UNIVERSITY OF YORK;UNIVERSITAET FUER BODENKULTUR WIEN;NORSK INSTITUTT FOR VANNFORSKNING;THE HEBREW UNIVERSITY OF JERUSALEM;UNIVERSITEIT UTRECHT;STOCKHOLMS UNIVERSITET";"ES;UK;AT;NO;IL;NL;SE";;1;0;0;1;0;0 213386;757397;NANOSTORM;SIGNED;H2020-EU.1.1.;ERC-2017-STG;H2020;Design of Nanomaterials for Targeted Therapies Guided by Super Resolution Imaging;2018-02-01;2023-01-31;;"Nanomaterials revolutionized the field of targeted cancer therapies introducing innovative approaches towards the molecular recognition of diseased cells. However, despite the large investments in nanotechnology-based drug delivery the translation into clinical applications is still unsatisfactory and up to date there are no actively-targeted materials approved for clinical use. One of the main reasons is the lack of knowledge about the behaviour of nanostructures in the biological environment that makes the rational design of effective drug delivery carriers extremely challenging. NANOSTORM proposes the use of an innovative optical imaging technique such as super resolution microscopy to visualize and understand the molecular interactions of nanomaterials with their cellular targets in unprecedented detail. We recently reported for the first time the ability of Stochastic Optical Reconstruction Microscopy (STORM) to image self-assembled synthetic materials in vitro with nanometric resolution. NANOSTORM aims to bring this to the next level, using STORM to unveil the structure-activity relations of therapeutic nanomaterials in the biological environment at the single molecule level. The knowledge arising from this investigation will provide novel design principles for the next generation of nanomaterials for targeted therapies. In particular, in the framework of NANOSTORM novel nanomaterials for the targeted treatment of prostate cancer will be synthesized and evaluated. This interdisciplinary research program will advance our understanding of nanostructures for targeted drug delivery and guide the formulation of novel materials for cancer therapy.";1497588;1497588;ERC-2017-STG;/ERC-STG;TECHNISCHE UNIVERSITEIT EINDHOVEN;NL;FUNDACIO INSTITUT DE BIOENGINYERIA DE CATALUNYA;ES;;1;0;0;1;0;0 212836;760858;InnovaConcrete;SIGNED;"H2020-EU.2.1.3.;H2020-EU.2.1.2.";NMBP-35-2017;H2020;Innovative materials and techniques for the conservation of 20th century concrete-based cultural heritage;2018-01-01;2020-12-31;;InnovaConcrete is an innovative and ambitious proposal that aims at preserving concrete-based monuments, the most significant tangible Cultural Heritage (CH) in the 20th Century. To achieve this goal, we have recruited an interdisciplinary team presenting a strong scientific background in simulation techniques and nanomaterials synthesis, combined with a wide knowledge of CH conservation from Humanities disciplines and, a sound industrial perspective. Specifically, a completely innovative approach based on producing C-S-H gel, responsible for the engineering properties of cement paste in cracks of decayed concrete monument, in situ, will be developed. Complementary, other innovative solutions giving rise to superhydrophobicity and corrosion inhibition will be also investigated. In addition, InnovaConcrete will explore an approach based on biotechnology: enzyme-assisted self-healing of damaged surfaces. The optimization of the solutions proposed will be carried out by the use of theoretical tools (multi-scale modelling approaches) together with experimental tools (laboratory and in situ validation). Significant 20th century monuments, such as the spectacular building, Centennial Hall, the open-air sculptures of Eduardo Chillida, War Memorial Towers and concrete shell structures, typical construction in communist period will be used as case studies to validate the performance of the solutions proposed. These monuments, a clear representation of European CH, will be employed to study economic and other societal effects of the proposal and to promote citizens' awareness of 20th century European heritage. Finally, the activities required for the future commercialization of the InnovaConcrete products, including standardization, certification, life cycle assessment, scaling up and exploitation strategies will be carried out.;6916287,5;6882086,5;H2020-NMBP-2017-two-stage;/RIA;UNIVERSIDAD DE CADIZ;ES;"IONFLY VACUUM AND PLASMA TECHNOLOGY SRL;CONSEIL INTERNATIONAL DES MONUMENTSET DES SITES ASSOCIATION;LUCIANO HERNANDEZ;FUNDACIÓN EDUARDO CHILLIDA Y PILAR BELZUNCE;INES INGENIEROS CONSULTORES SL;ESTUDIO GUADIANA SLP;SIKA TECHNOLOGY AG;NATIONAL TECHNICAL UNIVERSITY OF ATHENS - NTUA;FUNDACION TECNALIA RESEARCH & INNOVATION;TECHEDGE GMBH;ANONYMI ETAIREIA VIOMICHANIKIS EREVNAS, TECHNOLOGIKIS ANAPTYXIS KAI ERGASTIRIAKON DOKIMON, PISTOPIISIS KAI PIOTITAS;NANOTECMARIN GMBH;RINA CONSULTING SPA;AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS;STUDIECENTRUM VOOR KERNENERGIE / CENTRE D'ETUDE DE L'ENERGIE NUCLEAIRE;FUNDACION DOCOMOMO IBERICO;CONSIGLIO NAZIONALE DELLE RICERCHE;BEWARRANT;WISS, JANNEY, ELSTNER ASSOCIATES, INC;NANOPHOS ANONIMI EMPORIKI ETAIRIA ANAPTIXIS KAI YPIRESION - NANOPHOS COMMERCIAL SOCIETE ANONYME OF SERVICES AND DEVELOPMENT;TECHNISCHE UNIVERSITAT DARMSTADT;UNIVERSITAETSMEDIZIN DER JOHANNES GUTENBERG-UNIVERSITAET MAINZ;UNIWERSYTET LODZKI;MINISTERO PER I BENI E LE ATTIVITA CULTURALI;CONSORZIO INTERUNIVERSITARIO PERLO SVILUPPO DEI SISTEMI A GRANDE INTERFASE;WROCLAWSKIE PRZEDSIEBIORSTWO HALA LUDOWA SP ZOO;POLYTECHNEIO KRITIS;TECHNISCHE UNIVERSITEIT DELFT";"IT;FR;AR;ES;CH;EL;DE;BE;US;PL;NL";;1;0;0;1;0;0 212962;777544;PAPILA;SIGNED;H2020-EU.1.3.3.;MSCA-RISE-2017;H2020;Prediction of Air Pollution in Latin America;2018-01-01;2021-12-31;;"The overall objective of the PAPILA project (Prediction of Air Pollution in Latin America and the Caribbean) is to establish a sustained network of partners with complementary expertise, which will develop and implement an analysis and forecast system for air quality with downscaling capability for Latin America and the Caribbean region (LAC region), and assess the impact of air pollution (background and peaks) on health and on the economy. This forecast system will help decision-makers improve air quality and public health, and avoid the occurrence of acute air pollution episodes, particularly in urban areas. The project combines an ensemble of state-of-the-art models, high-resolution emission inventories, space observations and surface measurements to provide near real time forecasts and analysis of regional air pollution in the LAC region. To reach this objective, the project will bring together an interdisciplinary team of scientists from Europe, Latin America (Argentina, Bolivia, Brazil, Chile, Colombia, Mexico, Venezuela) and the Caribbean (Puerto Rico), and foster synergies between the groups involved in research and service activities. The project will co-develop with users and other stakeholders several products and services of importance for the LAC region. An important objective of the project is to make use of complementary competence to develop innovative ideas, to established sustained partnerships between research groups, to transfer information to the public, to develop educational activities and to create a dialogue with interested stakeholders. Societal impacts, specifically on human health, on crop production, on ecosystems, on the mountain snow cover and on the hydrological cycle as well as the economic benefits of mitigation policies will be assessed. Finally, the planned activities will provide the basis for sustained capacity building actions.";1467000;1188000;H2020-MSCA-RISE-2017;/MSCA-RISE;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;DE;"LEIBNIZ INSTITUT FUER TROPOSPHAERENFORSCHUNG e.V.;INSTITUT NATIONAL DE L ENVIRONNEMENT ET DES RISQUES INERIS;UNIVERSITE GRENOBLE ALPES;KONINKLIJK NEDERLANDS METEOROLOGISCH INSTITUUT-KNMI;ILMATIETEEN LAITOS;METEOROLOGISK INSTITUTT;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;STOCKHOLMS UNIVERSITET";"DE;FR;NL;FI;NO;SE";;1;0;0;1;0;0 212987;778001;DNASURF;SIGNED;H2020-EU.1.3.3.;MSCA-RISE-2017;H2020;Molecular diagnostics through DNA modification and interfacial engineering;2017-12-01;2021-11-30;;DNASURF will establish a global network of excellence for exchange of research staff and transfer of knowledge, to provide high-level training and career advancement opportunities, focussed on interdisciplinary DNA technology with a view to development of innovative solutions for DNA molecular diagnostics. It brings together leading academic and commercial scientific groups from 3 European and 4 non-European countries who will study complementary aspects of DNA synthesis, DNA nanoarchitectures, DNA at surfaces, and DNA for biomedical devices. DNASURF aims to transform creative scientific ideas into innovative biomedical products and services by exploiting and integrating advances in DNA synthesis, nanotechnology, interfacial engineering, and microsystems research. The pathway from basic science to commercial applications is facilitated by collaboration between academic labs and SMEs that are at the forefront of new methodologies. The ambitious scientific objectives of DNASURF are complemented by the aim to increase cutting-edge technical knowledge and professional skills across the network through staff exchanges and training in key methods as well as commercialisation of research. A long term goal of DNASURF is to consolidate a group of collaborative young multi-disciplinary scientists that can bring about future development of disruptive technologies in the commercially important scientific field of molecular diagnostics.;522000;499500;H2020-MSCA-RISE-2017;/MSCA-RISE;UNIVERSITY OF NEWCASTLE UPON TYNE;UK;"UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN;THE UNIVERSITY OF BIRMINGHAM;THE HEBREW UNIVERSITY OF JERUSALEM;UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA";"IE;UK;IL;ES";;1;0;0;1;0;0 212834;760891;CHIC;SIGNED;H2020-EU.2.1.4.;BIOTEC-07-2017;H2020;Chicory as a multipurpose crop for dietary fibre and medicinal terpenes;2018-01-01;2022-06-30;;"CHIC is the Chicory Innovation Consortium. Its objective is 1) to implement New Plant Breeding Techniques (NPBTs) in chicory in order to establish it as a multipurpose crop for the production of health-related products with clear benefits for consumers, and 2) to develop co-innovation pathways with stakeholders for game-changing technologies, such as NPBTs. CHIC will develop four different NPBTs. They will be used to steer bioprocesses in chicory and mobilize its under-explored potential to produce immunomodulatory prebiotics and medicinal terpenes. The conceptually different NPBTs will be assessed with respect to technological potential, risks, regulatory framework and their socio-economic impacts. This will be done in close consultation with a Stakeholder Advisory Group (SAG) composed of relevant stakeholders in industry and society. Ongoing project activities and results will be discussed with stakeholders and communicated to interested public using innovative methods including cultural communication and linking art to science. In this context, CHIC will develop two business cases in different application areas, inulin as healthy food ingredient and terpenes as medicinal lead compounds. This effort requires a highly interdisciplinary approach with expertise from molecular sciences, economy, arts, social sciences & humanities, and legislation. The partnership includes three SMEs and a chicory end-user, and international collaboration is established via a research institute in New Zealand. The SAG plays a crucial role in consultation in all phases and activities of the project. Via this co-innovation approach, we aim to contribute to leadership in responsible research innovation and to promote improved understanding of plant biotechnology. Chicory will be boosted as a robust multipurpose crop, tolerant to adverse environmental conditions from which bioactive compounds can be extracted, contributing to sustainable agriculture and a biobased economy.";7318346,25;6999596,25;H2020-NMBP-BIO-2017;/RIA;STICHTING WAGENINGEN RESEARCH;NL;"INSTITUT ZA BIOLOSKA ISTRAZIVANJA;JOANNEUM RESEARCH FORSCHUNGSGESELLSCHAFT MBH;EUROPESE ORGANISATIE VOOR WETENSCHAPPELIJK PLANTENONDERZOEK E.P.S.O. IVZW;TECHNISCHE UNIVERSITAET GRAZ;JULIUS KUHN-INSTITUT BUNDESFORSCHUNGSINSTITUT FUR KULTURPFLANZEN;THE NEW ZEALAND INSTITUTE FOR PLANT AND FOOD RESEARCH LIMITED;IDCONSORTIUM SL;Teknologian tutkimuskeskus VTT Oy;SENSUS BV;KEYGENE NV;FUNDACJA ART & SCIENCE SYNERGY FOUNDATION;UNIVERSITE DE LILLE;FONDAZIONE EDMUND MACH;LEIBNIZ-INSTITUT FUR PFLANZENBIOCHEMIE;WAGENINGEN UNIVERSITY;UNIVERSITE DES SCIENCES ET TECHNOLOGIES DE LILLE - LILLE I;INSTITUTO DE BIOLOGIA EXPERIMENTAL E TECNOLOGICA";"RS;AT;BE;DE;NZ;ES;FI;NL;PL;FR;IT;PT";;1;0;0;1;0;0 212955;777489;EURHISFIRM;SIGNED;H2020-EU.1.4.1.1.;INFRADEV-01-2017;H2020;Historical high-quality company-level data for Europe;2018-04-01;2021-03-31;;EURHISFIRM designs a world-class research infrastructure (RI) to connect, collect, collate, align, and share detailed, reliable, and standardized long-term financial, governance, and geographical data on European companies. EURHISFIRM enables researchers, policymakers, and other stakeholders to develop and evaluate effective strategies to promote investment, economic growth and job creation. The RI provides the tools for long-term analysis highlighting the dynamics of the past and the way those dynamics structure our present and future. A few large stand-alone long-term databases have been built in Europe so far, while important resources have been invested into scattered and dispersed historical datasets. EURHISFIRM develops innovative models and technologies to spark a “Big data” revolution in historical social sciences and valorize Europe’s cultural heritage. These technologies match and collate historical data, and connect them to recent ones. They bring the next generation of data extraction and enrichment systems from digitized historical sources and web-based resources. The scaling up in the variety, quantity and quality of long-term data changes the way of conducting scientific enquiry in the historical social sciences. EURHISFIRM constitutes a vibrant and large users’ community around the innovative data and services provided. The 2016 ESFRI Roadmap identifies Big Data, interdisciplinarity and innovative ways to disseminate research products as the main science drivers for RIs in the Social Sciences and Humanities. It recognizes the need and the opportunity for RIs providing access to the European Cultural Heritage and innovative methods to analyze and integrate information extracted to broad communities. EURHISFIRM fulfills this mission in close cooperation with ESFRI Landmark CESSDA and other existing RIs in the field of Arts and Humanities, like DARIAH, within the Research Data Alliance.;3385860;3385610;H2020-INFRADEV-2017-1;/RIA;ECOLE D'ECONOMIE DE PARIS;FR;"UNIVERSITEIT ANTWERPEN;GESIS-LEIBNIZ-INSTITUT FUR SOZIALWISSENSCHAFTEN EV;UNIVERSITE DE ROUEN NORMANDIE;KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW;UNIWERSYTET EKONOMICZNY WE WROCLAWIU;INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE RENNES;THE QUEEN'S UNIVERSITY OF BELFAST;JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN;ERASMUS UNIVERSITEIT ROTTERDAM;UNIVERSIDAD CARLOS III DE MADRID";"BE;DE;FR;NL;PL;UK;ES";;1;0;0;1;0;0 212857;764465;OpenGTN;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2017;H2020;Open Ground Truth Training Network : Magnetic resonance image simulationfor training and validation of image analysis algorithms;2018-01-01;2021-12-31;;"This action aims to optimally prepare three young researchers for the evolving medical imaging world by offering a unique set of targeted interdisciplinary training and research assignments in the areas of anatomy, pathology, imaging techniques, quantitative image analysis and segmentation, Magnetic Resonance (MR) physics and MR image simulation. MR imaging is the major imaging modality for brain and spine anatomy and pathology. A clear trend can be observed from visual to computer-assisted diagnosis by quantification of disease-specific biomarkers, derived from the MR images. The major components in image quantification applications are tissue and organ segmentation and classification. Manual segmentation is too tedious and cumbersome for daily clinical practice and would lead to large inter-user variability. Much research is therefore performed on automatic segmentation techniques. Training, validation and benchmarking of these techniques is currently impeded by the lack of MR image databases with exact reference segmentations. The research will follow an innovative approach to overcome the current barriers for wide uptake of automatic segmentation. By combining mathematical organ models with physical and biological tissue properties and image simulation methods, substantial public image databases will be established providing ample MR images with ground truth (exact) segmentations, by which fast and accurate optimization and validation of image segmentation algorithms will be enabled. Based on sound career development plans, and coached by experienced supervisors a training is offered by leading image analysis research groups from Philips (global leader in medical imaging) and the Eindhoven University of Technology (world-wide recognized authority in education and research on image analysis, esp. on MRI) and supported by researchers from leading clinical centers as UMC Utrecht, TU Munich, Kings College London and the German Center for Neurodegenerative Diseases.";766122,84;766122,84;H2020-MSCA-ITN-2017;/MSCA-ITN-EID;TECHNISCHE UNIVERSITEIT EINDHOVEN;NL;Philips GmbH;DE;;1;0;0;1;0;0 213029;778412;INDESMOF;SIGNED;H2020-EU.1.3.3.;MSCA-RISE-2017;H2020;International Network on Ionic Liquid Deep Eutectic Solvent Based Metal Organic Frameworks Mixed Matrix Membranes.;2018-03-01;2022-02-28;;The main objective of INDESMOF Marie Curie RISE action is to establish a new and lasting research consortium to improve and exchange interdisciplinary and intersectoral knowledge on the design, synthesis, and characterization of advanced composite adsorbents for environmental remediation of heavy metal polluted water sources, able to provide high capacity and high selectivity filters for the industry. The main research core of INDESMOF is based on the nano-encapsulation of Deep Eutectic Solvents (DES) within the ordered porous structures of Metal Organic Frameworks (MOF), in order to obtain a highly porous MOF material, combined with the metal chelation and solvation specificity of DES. Incorporation of high-capacity high-selectivity adsorbent materials within polymeric support is a crucial challenge faces in INDESMOF towards the real application of the MOF@DES materials in water filtering systems, indispensable for mining and industrial water environmental remediation technologies. Development and improvement of advanced filtering technologies requires the joint effort of a multidisciplinary researcher collective, involving the expertise of participants on different disciplines including physics, chemistry, environmental chemistry, materials and polymer science and engineering. Background knowledge and knowhow of INDEMOF´s partners combine the complementarities and synergies needed to undertake an integrative and concerted effort through innovation and breakthrough actions towards the fabrication of advanced and specific filters for polluted water remediation. Results will be widely disseminated through publications, workshops, post-graduate courses to train new researchers, a dedicated webpage, and visits to companies working in the area. In that way, we will perform an important role in technology transfer in the design of highly active and selective adsorbents and their performance against real water polluted samples.;774000;774000;H2020-MSCA-RISE-2017;/MSCA-RISE;FUNDACION BCMATERIALS - BASQUE CENTRE FOR MATERIALS, APPLICATIONS AND NANOSTRUCTURES;ES;"TEKNIMAP AMBIENTAL SL;AGENCIA VASCA DEL AGUA URA;UNIVERSITA DEGLI STUDI DI TORINO;UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA";"ES;IT";;1;0;0;1;0;0 200093;693781;EULAC Focus;SIGNED;H2020-EU.3.6.;INT-12-2015;H2020;Giving focus to the Cultural, Scientific and Social Dimension of EU – CELAC Relations;2016-03-01;2019-08-31;;"EULAC Focus addresses the whole set of topics included in the Call. It delivers a significant contribution to the improvement of EU–CELAC relations through a better understanding of the three dimensions selected by the call: cultural, scientific and social. The main objective is that of “giving focus” to these three dimensions of EU–CELAC relations, with a view to determining synergies and cross-fertilization, as well as identifying asymmetries in bi-lateral and bi-regional relations. Research is focused on areas crucial to explain the current state of relations between EU and LAC, and will be pursued at two levels: a) research activities; b) strategic set of recommendations. In order to guarantee high impact, the research is pursued in six interdisciplinary WPs, organized “matricially”. Three are “horizontal ”: Cross-cutting pathways, Towards a common vision for EU–CELAC and Dissemination and outreach. The other three are “thematic/vertical”: Cultural, Scientific and Social Dimension, and not only intersect the horizontal WPs but also interact between them. To achieve the objectives, the project is organized by the multidisciplinary and well balanced consortium of19 members from 15 counties. The consortium represents a unique group of highly competent and experienced institutions, composed specifically for the purpose of this project,comprising, in both regions, Gov Research Agencies, Research institutes, Universities, University Association, and two International European – LA Organizations active in analytical and policy oriented research and dissemination. EULAC Focus builds upon the outcomes of prior mapping conducted at the bi-regional level and will facilitate access to end-users, as well as feeding into the work of the EU-LAC Foundation and informing bi-regional networking activities of the JIRI and T-AP’s work. The number of partners has been carefully defined to ensure project goals and proper diversity, while allowing for efficient project management.";2567621,25;2499652,5;H2020-INT-SOCIETY-2015;/RIA;UNIVERSITAT DE BARCELONA;ES;"NEDERLANDSE ORGANISATIE VOOR WETENSCHAPPELIJK ONDERZOEK;UNIVERSIDAD DE INVESTIGACION DE TECNOLOGIA EXPERIMENTAL YACHAY;Consejo Superior Universitario Centroamericano;METCENAS OPS;THE UNIVERSITY OF THE WEST INDIES U WI*;FUNDACAO DE APOIO A UNIVERSIDADE DE SAO PAULO;Pontificia Universidad Catolica del Peru;DEUTSCHES ZENTRUM FUER LUFT - UND RAUMFAHRT EV;UNIVERSIDAD DE BUENOS AIRES;ZENTRUM FUR SOZIALE INNOVATION GMBH;UNIVERSIDAD DE CHILE;STIFTUNG PREUSSISCHER KULTURBESITZ;SAMUI FRANCE SARL;SECRETARIA NACIONAL DE CIENCIA Y TECNOLOGIA;ORGANIZACION DE ESTADOS IBEROAMERICANOS PARA LA EDUCACION LA CIENCIA Y LA CULTURA;UNIVERSIDAD NACIONAL AUTONOMA DE MEXICO;INSTITUTO ITALO-LATINO AMERICANO;Ministerio de Ciencia, Tecnología e Innovación Productiva";"NL;EC;GT;CZ;JM;BR;PE;DE;AR;AT;CL;FR;ES;MX;IT";;1;0;0;1;0;0 212397;773400;SEAFOODTOMORROW;SIGNED;H2020-EU.3.2.5.;BG-08-2017;H2020;Nutritious, safe and sustainable seafood for consumers of tomorrow;2017-11-01;2020-10-31;;"SEAFOODTOMORROW aims to validate and optimize commercial solutions for improving the socioeconomic and environmental sustainability of the seafood production and processing industry, while contributing to product quality and safety. Activities will focus on the sustainable production and processing of nutritious and safe seafood products through the demonstration and first application in the market of eco-innovative, sustainable solutions of marine and aquaculture-derived food products and nutrients. The proposal will take into account impacts across different regions and population segments, as well as the specificities of different types of seafood. Activities will include among others: utilization of agro and seafood byproducts to develop sustainable feeds for aquaculture enabling the production of tailor made products fortified with specific essential nutrients for consumers, assess the feasibility of salt replacers in seafood, validate digestible, attractive, functional and nutritionally adapted seafood for senior people and youths, validate strategies to prevent/remove contaminants from seafood, and optimize sensors and biosensors for the assessment of safety, among others. The consortium expects strengthening the wider utilization of eco-innovative solutions, as a result of greater user acceptance, higher visibility of these innovative solutions and creation of scalable markets, and increasing the availability of healthier seafood to improve consumers' diet and health. The consortium is built on interdisciplinary research teams of 19 RTDs involved, renowned by its top-quality applied technological development and with strong and cohesive links gathered in previous funded activities (e.g. FP7 ECsafeSEAFOOD), thus anticipating successful outcomes. In addition, 4 IAGs and 13 SMEs with diverse and complementary interests in the solutions under validation and optimization will also integrate the consortium.";7516875,48;6996032,25;H2020-BG-2017-1;/IA;INSTITUTO PORTUGUES DO MAR E DA ATMOSFERA IP;PT;"UNIVERSITAT ROVIRA I VIRGILI;XENOBICS LTD;THE SECRETARY OF STATE FOR ENVIRONMENT, FOOD AND RURAL AFFAIRS;AquaTT UETP Ltd;SPREAD EUROPEAN SAFETY GEIE;UNIVERSITEIT GENT;ISTITUTO SUPERIORE DI SANITA;Campden BRI Magyarorszag Nonprofit Korlatolt Felelossegu Tarsasag;ASOCIACION NACIONAL DE FABRICANTES DE CONSERVAS DE PESCADOS Y MARISCOS-CENTRO TECNICO NACIONAL DE CONSERVACION DE PRODUCTOS DE LA PESCA;TARELAKS AS;RISE RESEARCH INSTITUTES OF SWEDEN AB;AQUIMER;AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS;EIGEN VERMOGEN VAN HET INSTITUUT VOOR LANDBOUW- EN VISSERIJONDERZOEK;PREDELL SERVICES;THE QUEEN'S UNIVERSITY OF BELFAST;AEIFORIA SRL;WESTCOUNTY MUSSELS OF FOWEY LTD;SPAROS LDA;RIJKSINSTITUUT VOOR VOLKSGEZONDHEID EN MILIEU;EUROPEAN FOOD INFORMATION RESSOURCE AISBL;INSTITUT DE RECERCA I TECNOLOGIA AGROALIMENTARIES;INSTITUT TECHNIQUE DE DEVELOPPEMENT DES PRODUITS DE LA MER;DANMARKS TEKNISKE UNIVERSITET;MOREFORSKING ALESUND AS;SKALOMA AE;FUNDACION AZTI - AZTI FUNDAZIOA;CIIMAR - Centro Interdisciplinar de Investigaç?o Marinha e Ambiental;MRAG LIMITED;ICETA INSTITUTO DE CIENCIAS, TECNOLOGIAS E AGROAMBIENTE DA UNIVERSIDADE DO PORTO;EUROPEAN CONSUMERS UNION;INSKIE CENTRUM RYBACTWA SPOLKA ZOO;PTC PHAGE TECHNOLOGY CENTER GMBH;ZACHODNIOPOMORSKI UNIWERSYTET TECHNOLOGICZNY W SZCZECINIE";"ES;UK;IE;IT;BE;HU;NO;SE;FR;PT;NL;DK;EL;PL;DE";;1;0;0;1;0;0 211892;765408;COUPLED;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2017;H2020;Operationalising telecouplings for solving sustainability challenges related to land use;2018-01-01;2021-12-31;;Society depends on land for food, feed, fibre and energy, but the detrimental outcomes of unsustainable land practices are becoming increasingly apparent. Ensuring sustainable land use is a key challenge, yet hard to achieve in today’s interconnected world where policies, consumer demands and environmental change in one region may affect far-away places. We face a significant knowledge gap regarding the processes related to land use that link distant places – or telecouplings – and how these processes could be governed towards sustainability. Companies, institutions and policy makers lack the expertise and tools to ensure sustainable land use in a globalised world. COUPLED will educate researchers and entrepreneurs in assessing and governing land use in a systemic way, accounting for the opportunities and threats arising from distal links between Europe and other regions. COUPLED builds on a strong interdisciplinary network to achieve its overall objective of operationalising the novel telecouplings concept in order to support sustainable governance of land systems and related supply chains under global change. COUPLED will deliver on training a new generation of professionals and entrepreneurs, developing rich analytic tools and new understandings to help private and public organisations to identify where and how they can intervene to make sustainable land use decisions, thereby avoiding unwanted outcomes. The consortiums unites scientifically excellent partners across the natural and social sciences to ensure excellence in research, institutional and technological innovation. Working closely with large companies, SMEs, NGOs, international organisations and administrative bodies, the ESRs will learn how to move between science and practice, become highly attractive to employers, and build successful careers in research, consulting, industry or governance. The action will thus contribute to Europe’s leading position for a transformation towards sustainable land use.;3895103,16;3895103,16;H2020-MSCA-ITN-2017;/MSCA-ITN-ETN;HUMBOLDT-UNIVERSITAET ZU BERLIN;DE;"STICHTING VU;UNIVERSITAET BERN;KOBENHAVNS UNIVERSITET;UNIVERSITE CATHOLIQUE DE LOUVAIN;LEUPHANA UNIVERSITAT LUNEBURG;THE FOREST TRUST LBG;UNIVERSITAET FUER BODENKULTUR WIEN;UNIVERSITAET KLAGENFURT;UNIVERSITAT AUTONOMA DE BARCELONA;UNILEVER U.K. CENTRAL RESOURCES LIMITED";"NL;CH;DK;BE;DE;UK;AT;ES";;1;0;0;1;0;0 212316;758502;COMICS;SIGNED;H2020-EU.1.1.;ERC-2017-STG;H2020;Children in Comics: An Intercultural History from 1865 to Today;2018-10-01;2023-09-30;;"Owing to their visual essence and status as a popular, modern medium, comics – newspaper strips, comics magazines and graphic novels – provide valuable insight into the transformation of collective consciousness. This project advances the hypothesis that children in comics are distinctive embodiments of the complex experience of modernity, channeling and tempering modern anxieties and incarnating the freedom denied to adults. In testing this hypothesis, the project constructs the first intercultural history of children in European comics, tracing the changing conceptualizations of child protagonists in popular comics for both children and adults from the mid-19th century to the present. In doing so, it takes key points in European history as well as the history of comics into account. Assembling a team of six multilingual researchers, the project uses an interdisciplinary methodology combining comics studies and childhood studies while also incorporating specific insights from cultural studies (history of family life, history of public life, history of the body, affect theory and scholarship on the carnivalesque). This enables the project to analyze the transposition of modern anxieties, conceptualizations of childishness, child-adult power relations, notions of liberty, visualizations of the body, family life, school and public life as well as the presence of affects such as nostalgia and happiness in comics starring children. The project thus opens up a new field of research lying at the intersection of comics studies and childhood studies and illustrates its potential. In studying popular but often overlooked comics, the project provides crucial historical and analytical material that will shape future comics criticism and the fields associated with childhood studies. Furthermore, the project’s outreach activities will increase collective knowledge about comic strips, which form an important, increasingly visible part of cultural heritage.";1452500;1452500;ERC-2017-STG;/ERC-STG;UNIVERSITEIT GENT;BE;KATHOLIEKE UNIVERSITEIT LEUVEN;BE;;1;0;0;1;0;0 212411;774199;IRIS;SIGNED;H2020-EU.3.3.1.;SCC-1-2016-2017;H2020;Integrated and Replicable Solutions for Co-Creation in Sustainable Cities;2017-10-01;2022-09-30;;"The IRIS project supports the Lighthouse cities of Utrecht (NL), Göteborg (SE) and Nice Côte d’Azur (FR) and their Follower cities Vaasa (FI), Alexandroupolis (GR), Santa Cruz de Tenerife (ES), and Focsani (RO) to address their urgent need to deliver energy and mobility services in their cities that are cheaper, better accessible, reliable, and that contribute to a better and more sustainable urban quality of life. By demonstrating smart solutions that integrate energy, mobility and ict, rooted in a City Innovation Platform, IRIS quantifies their value, and connects interests of many different stakeholders in innovative business models, allowing for upscale and replication of integrated solutions for sustainable cities across Europe and world-wide. To achieve this, IRIS works along five Transition Tracks based on common challenges, encompassing 16 integrated solutions that cities can mix and match according to their characteristics and district specific needs. Track 1, 2 and 3 enhance energy efficiency and utilize grid flexibility by balancing supply and demand dynamically and by 2nd life battery and V2G storage, to allow increase of renewable energy production and roll-out of e-cars and e-buses. Track 4 supports this by data sharing, a common architecture, use of standards, and governance practices accelerating innovation, standardisation and implementation of affordable smart applications. Track 5 integrates interdisciplinary citizen engagement and co-creation in Tracks 1 to 4, connecting the needs of end-users with those of other stakeholders, in further support of innovative business models. The expected impacts of IRIS are an open innovation ecosystem motivating citizens to act as prosumers; more effective urban planning and governance of integrated solutions; exploitation of validated innovative business models based on multi-stakeholder collaboration; more stable, secure and affordable energy and mobility services for citizens, with improved air quality.";20769279,77;17996569,05;H2020-SCC-2017;/IA;GEMEENTE UTRECHT;NL;"RIKSBYGGEN EKONOMISK FORENING;ENECO ZAKELIJK BV;VEOLIA INNOVE;VAASAN YLIOPISTO;ENEDIS;METRY AB;INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU ENERGIE ICEMENERG-BUCURESTI;ETHNIKO KENTRO EREVNAS KAI TECHNOLOGIKIS ANAPTYXIS;STICHTING HOGESCHOOL VOOR DE KUNSTEN UTRECHT;STEDIN NETBEHEER BV;METROPOLE NICE COTE D'AZUR;ASOCIACION CLUSTER CONSTRUCCION SOSTENIBLE;ELECTRICITE DE FRANCE;TYRENS AB;UNIVERSITE DE NICE SOPHIA ANTIPOLIS;QBUZZ B.V.;VRIJE UNIVERSITEIT BRUSSEL;MINICIPALITY OF ALEXANDROUPOLIS;ENECO CONSUMENTEN BV;RISE RESEARCH INSTITUTES OF SWEDEN AB;HSB GOTEBORG EK FOR;AYUNTAMIENTO DE SANTA CRUZ DE TENERIFE;ENERGY HIVE SYSTADA EPICHEIRISEON ENERGEIAS KAI FYSIKON PORON ANATOLIKIS MAKEDONIAS KAI THRAKIS;VAASAN KAUPUNKI;NEXIMMO 96;AKADEMISKA HUS AKTIEBOLAG;STICHTING BO-EX 91;CENTRE SCIENTIFIQUE ET TECHNIQUE DU BATIMENT;GOTEBORGS KOMMUN;KONINKLIJKE KPN NV;JOHANNEBERG SCIENCE PARK;CIVITY BV;UNIVERSITATEA POLITEHNICA DIN BUCURESTI;UNIVERSITEIT UTRECHT;COTE D'AZUR HABITAT;VU LOG;OY MERINOVA AB;EUROPEAN SCIENCE COMMUNICATION INSTITUTE (ESCI) GGMBH;MUNICIPIUL FOCSANI;IMCG SWEDEN AB;TRIVECTOR TRAFFIC AB;PARKHUIS LOMBOK;CHALMERS TEKNISKA HOEGSKOLA AB";"SE;NL;FR;FI;RO;EL;ES;BE;DE";;1;0;0;1;0;0 211888;765376;eSCALED;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2017;H2020;European School on Artificial Leaf : Electrodes Devices;2018-04-01;2022-03-31;;"Climate change resulting from accumulation of anthropogenic carbon dioxide in the atmosphere and the uncertainty in the amount of recoverable fossil fuel reserves are driving forces for the development of renewable, carbon-neutral energy technologies. Artificial photosynthesis appears to be an appealing approach for a sustainable energy generation as it produces “solar fuels” or commodities for chemistry in a stable and storable chemical form, from solar energy, H2O & CO2. The eSCALED project is a contribution to structure early-stage research training at the European level and strengthen European innovation capacity to elaborate an artificial leaf. The ESR will be in charge of combining in a unique device a solar cell and a bioinspired electrochemical stack where H2O oxidation and H\ or CO2 reduction are performed in microreactors. The novelties in this project are at two levels: (1) Developing sustainable joint doctoral degree structure based on inter/multidisciplinary aspects of biological/biochemical, condensed, inorganic & soft matter to device engineering and innovation development. (2) Scientifically using, cheap and easy processes tandem organic solar cells, earth-abundant materials for water splitting, new generation of catalysts and natural/artificial hydrogenase enzymes for hydrogen production, formate dehydrogenases for catalytic carbon dioxide reduction, new proton-exchange fluorinated membranes and finally, electrode micro porosity to mimic the chloroplasts of a plant. The eSCALED collaborative project brings together for the first time, 12 internationally recognized academic and industrial research groups. The project has an interdisciplinary scientific approach integrating the latest knowledge on catalysis, photovoltaic and polymer chemistry for self-structuration. Major outcomes will include breakthroughs in the development of artificial photosynthetic leaf as a photoelectrochemical device, highly trained researchers & new partners collaborations.";3599025,2;3599025,2;H2020-MSCA-ITN-2017;/MSCA-ITN-EJD;UNIVERSITE DE PAU ET DES PAYS DE L'ADOUR;FR;"FUNDACIO PRIVADA INSTITUT CATALA D'INVESTIGACIO QUIMICA;COLLEGE DE FRANCE;COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES;UPPSALA UNIVERSITET;RIVA GMBH BATTERIES;FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA;UNIVERSITAET STUTTGART;FUNDACIO EURECAT;TECHNISCHE UNIVERSITEIT EINDHOVEN;SOLARONIX SA;UNIVERSITE DE NAMUR ASBL";"ES;FR;SE;DE;IT;NL;CH;BE";;1;0;0;1;0;0 211905;766007;MAMI;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2017;H2020;Magnetics and Microhydrodynamics - from guided transport to delivery;2018-05-01;2022-04-30;;This multidisciplinary network entitled: “Magnetics and Microhydrodynamics - from guided transport to delivery” (MaMi) bridges the research fields of fluidics and magnetism, by taking advantage of magnetic forces to control local flows and cargo transport inspired by biomimetic systems. Using magnetic sources, as well as high magnetic susceptibility liquids or nanostructures, devices with unique anti-fouling properties and non-slip boundary conditions can be realized. Our scientific aim is to take advantage of such unique wall-less properties to create new applications of microfluidic technology for life sciences. The network assembles and interdisciplinary team of seven academic and five non-academic partners, exposes all students to industrial environments, and ensures training at the frontiers of two well-established research fields, which are not commonly associated. Over the course of their projects, early stage researchers based in academic institutions will experience working environments in at least 3 different countries. Training a new generation of researchers will bring new cutting-edge knowledge, and will ensure a high potential for industrial applications to promote EU leadership.;3757056,48;3757056,48;H2020-MSCA-ITN-2017;/MSCA-ITN-ETN;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FR;"THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN;INSTITUT JOZEF STEFAN;ELVESYS SAS;UNIVERSITE DE STRASBOURG;KOLEKTOR GROUP VODENJE IN UPRAVLJANJE DRUZB DOO;LATVIJAS UNIVERSITATE;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA";"IE;SI;FR;LV;DE;ES";;1;0;0;1;0;0 211879;764965;EPIDIVERSE;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2017;H2020;Epigenetic Diversity in Ecology;2017-09-01;2021-08-31;;"Plants are the foundation of all ecosystems and they provide humans with essential services. Unprecedented rates of global environmental change are now putting plants under increased risk, and it is important to understand the capacity of plants to adapt to rapid change. EPIDIVERSE takes a cross-disciplinary approach to investigate the role that epigenetic mechanisms, specifically DNA methylation, play in plant adaptation. Understanding the epigenetic contribution to adaptation will help to predict species responses to global warming and can open new directions for sustainable agriculture and crop breeding. In EPIDIVERSE, a consortium of academic and entrepreneurial PIs will train 15 ESRs to become a first generation of expert eco-epigeneticists, equipping them with the interdisciplinary skills - molecular, (epi)genomic, ecological and bioinformatics - to successfully tackle this new research area. Training in leading academic groups and in life sciences companies will emphasize empirical and informatics skills to become fluent and creative in extracting knowledge from big ‘omics data in natural contexts. In so doing, EPIDIVERSE will ensure the ESRs, and Europe, leading positions in this emerging field. To explain the real-life relevance of epigenetics in natural systems, we will (1) develop genomic and bioinformatics tools for epigenomic analysis in natural settings; (2) determine natural epigenetic diversity, and its relationship with environmental factors, in three common wild species across Europe; and (3) reveal the molecular mechanisms underlying natural epigenetic diversity through controlled experiments. This approach is innovative and timely because it integrates several so far disconnected areas of epigenetic research, and it will transfer analytical methods from laboratory research to the real world. These are important steps forward if Europe wants to understand, manage, and possibly enhance plant adaptability to pressing environmental challenges.";3784150,8;3784150,8;H2020-MSCA-ITN-2017;/MSCA-ITN-ETN;KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW;NL;"PHILIPPS UNIVERSITAET MARBURG;MARTIN-LUTHER-UNIVERSITAET HALLE-WITTENBERG;BOTANICKY USTAV AV CR, V.V.I.;AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS;IGA TECHNOLOGY SERVICES SRL;GREGOR-MENDEL-INSTITUT FÜR MOLEKULARE PFLANZENBIOLOGIE GMBH;ECSEQ BIOINFORMATICS GMBH;EBERHARD KARLS UNIVERSITAET TUEBINGEN;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE;INSTITUT DE RECHERCHE POUR LE DEVELOPPEMENT;ECSEQ GMBH";"DE;CZ;ES;IT;AT;FR";;1;0;0;1;0;0 211878;764958;NANOSTEM;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2017;H2020;New nanomaterials for neural stem cells drug delivery;2018-06-01;2022-05-31;;Brain conditions such as neurodegenerative diseases, stroke and traumatic injuries are a mayor burden in modern society. Because neural stem cells (NSCs) can differentiate into new neural cells including neurons, the regulation of their proliferation, differentiation and migration represent a promising regenerative/therapeutic strategy. The hypothesis of NanoStem project is that novel nanoparticles (NPs) combined with recent identified/developed pharmaceuticals can be an efficient approach to control the biological activity of NSCs. The scientific project is organized in three work packages (WP), each focusing on specific objectives and containing well-defined deliverables. WP1 will focus on the synthesis of the nanomaterials and the uploading of the therapeutics. WP2 will take the best nanoparticles and focus more on the evaluation of the permeation and efficacy of the formulations against NSCs. WP3 will focus on in vivo studies to evaluate the formulations developed to tackle the brain and to assess their toxicity. The project will train 14 ESRs in areas including organic and polymer chemistry, cell biology, pharmacology, neuroscience, nanobiotechnology and clinical sciences. The project will also provide a substantial training program in complementary skills, targeting both professional and personal development, and translation of research and entrepreneurship. The project brings together six academic partners, one hospital and two industrial teams as full partners, complemented by four associate partners, one of which is an industrial team, distributed over a total of seven European Union member states. The consortium brings together groups with a very interdisciplinary expertise ranging from nanoparticle synthesis and characterization, computational modeling, in vitro BBB models and BBB transport, neural stem cells, animal testing and clinical expertise.;3590354,52;3590354,52;H2020-MSCA-ITN-2017;/MSCA-ITN-ETN;QUEEN MARY UNIVERSITY OF LONDON;UK;"HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH;THE UNIVERSITY OF BIRMINGHAM;CENTRO DE NEUROCIENCIAS E BIOLOGIACELULAR ASSOCIACAO;CENTRO HOSPITALAR E UNIVERSITARIO DE COIMBRA E.P.E.;KAROLINSKA INSTITUTET;THE UNIVERSITY OF WARWICK;MJR PHARMJET GMBH;UNIVERSITAET INNSBRUCK;UNIVERSITE D'ARTOIS";"DE;UK;PT;SE;AT;FR";;1;0;0;1;0;0 211898;765635;xCLASS;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2017;H2020;Next generation Compact Lightsource And Spectrometer Systems;2017-09-01;2021-08-31;;"Increasing health and environmental awareness of European citizens has led to an urgent demand for spectral analysis of matter. However, what is missing are novel and cost-effective methods to sense the desired analytes with high sensitivity and high reliability using small and portable devices. Moreover, there is a severe shortage in the European spectroscopy industry of graduates and PhDs with the right expertise along the complete technology supply chain for the development of such micro-spectrometer systems. Training and education in all its aspects, namely in optical modeling and design, fabrication and prototyping, measurements and characterization, sensor readout and data analysis towards proof-of concept demonstration up to industrial valorisation of the micro-spectrometer systems is crucial, but to our knowledge not offered today as a whole. In response, xCLASS sets up a training through research programme, provided by a consortium of a leading academic centre (VUB) and a leading industrial partner (Anteryon), in which four ESRs will work on a disruptive compact high-performance micro-spectrometer concept, broadly applicable in various application domains. All ESRs will be enrolled in the PhD programme at VUB, the academic partner of xCLASS. The recruited researchers will be exposed to an integrated highly collaborative and interdisciplinary research environment where VUB and Anteryon together cover the complete supply chain. The combination of a broad and in-depth education and training in the complete technology supply chain of optical spectrometer systems and the extensive training in transferable skills that the ESRs will experience in xCLASS will optimally prepare them for a successful career as photonic scientists in European academy and the photonics industry. Beyond the impact on the structural training programme, xCLASS will result in a significant societal and economic impact in healthcare, environmental and food safety sectors for whole Europe.";1011868,56;1011868,56;H2020-MSCA-ITN-2017;/MSCA-ITN-EID;VRIJE UNIVERSITEIT BRUSSEL;BE;ANTERYON BV;NL;;1;0;0;1;0;0 211565;765774;ASSTRA;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2017;H2020;Advanced Solid State Transformers;2018-01-01;2021-12-31;;"ASSTRA is an interdisciplinary training and research project that targets the development of advanced solid state transformer technology which enables a sustainable and flexible (‘Smart’), DC-equipped energy supply system with a large share of renewable energy sources. This futuristic electrification network has in its core a flexible power conversion unit, distributing electrical energy from sources to loads in a similar fashion as today’s internet hubs distribute information from senders to receivers. Specifically, this power conversion unit integrates state-of-the-art technology, such as Silicon-Carbide, in order to implement power electronics building blocks and magnetic components featuring breaking through performances, which will ultimately enable its industrial deployment. ASSTRA involves a two-partner network comprising the Eindhoven University of Technology (TU/e) in the Netherlands and ABB Corporate Research Center in Switzerland as beneficiaries. These partners complement each other in order to cover the knowledge and expertise fields required for the proposed program. A board of 6 experienced supervisors will intensively work together across a multitude of disciplines, including power electronics engineering, mechanical engineering, software engineering, material sciences and magnetics design, to train and mentor 2 Early Stage Researchers who will have access to excellent research facilities and close coaching approaches at both locations";510748,56;510748,56;H2020-MSCA-ITN-2017;/MSCA-ITN-EID;TECHNISCHE UNIVERSITEIT EINDHOVEN;NL;ABB SCHWEIZ AG;CH;;1;0;0;1;0;0 211763;767092;STARDUST;SIGNED;H2020-EU.1.2.1.;FETOPEN-01-2016-2017;H2020;in vivo optogeneticS, elecTrophysiology and phArmacology with an ultRasonically-powered DUST for Parkinson's Disease;2017-10-01;2021-09-30;;"The main goal of the STARDUST project is to realize a novel wireless implantable and independent micro-scale device (200x200x200 µm3) enabling in-vivo electrophysiology, optogenetics and ultra-localized drug delivery in freely moving animals. The device will be used to target specific neural circuits of the brain and test a new therapeutic approach for Parkinson’s Disease (PD). The methods used in this project are based on cutting-edge miniaturized technology combining integrated chips, microelectromechanical systems (MEMS), local drug delivery, integrated electrodes and micro-scale light emitting diodes (µLEDs). STARDUST will benefit from these advances and for the first time provide an implantable ultrasonically-powered miniaturized device for in-vivo optogenetics, local drug delivery and electrophysiological monitoring – all in one single device. The proposed device is expected to provide an output power of 1-20 mW/mm2 for optogenetics with two different wavelengths, one for neuron activation and one for triggering drug-delivery; STARDUST will provide proof of concept. The main novelty of the STARDUST project is the convergence of multiple, interdisciplinary fields including optogenetics, triggered drug-delivery, miniaturized ultrasonic energy harvesting, material science and nanoelectronics. The main ambition of the project is to develop a new technology platform to be used for future implantable in-vivo optogenetic devices for monitoring and treating diseases, with an optional local drug delivery add-on beyond 2025. Establishing proof of concept of the STARDUST platform will be the foundation for other applications within photodynamic therapy such as cancer treatment and other neurological and non-neurological disorders.";3803057,5;3787932,5;H2020-FETOPEN-1-2016-2017;/RIA;AARHUS UNIVERSITET;DK;"BIOMODICS APS;FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.;SPINVERSE OY;VIB;HUMBOLDT-UNIVERSITAET ZU BERLIN;Universidade Federal do Pará;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK";"DK;DE;FI;BE;BR;FR;IE";;1;0;0;1;0;0 211765;765048;STIMULATE;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2017;H2020;Simulation in multiscale physical and biological systems;2018-06-01;2022-05-31;;Simulation alongside theory and experiment is nowadays considered an integral part of scientific discovery. As computation speeds up and new technologies and instruments improve, data generation in all fields of science is rapidly increasing. As a consequence, researchers face new challenges: Data collection exceeds by far the capacity to validate, analyze, visualize, store, and curate the information contained. Additionally, traditional, single-scale, macroscopic physical models are becoming inadequate for the accuracy requirements of modern physical, biological and engineering applications that involve multiscale phenomena occurring over vastly different scales. Tackling these challenges will transform our approach to research potentially leading to unprecedented data-driven scientific discoveries. The overall goal of STIMULATE is to deliver an innovative interdisciplinary educational and research program in simulation and data science, which educates students to best address the challenges posed by exascale computing and intensive data applications, producing computational science professionals tactically positioned to become leaders in both academia and industry. The project proposes a rigorous network-wide training program and research projects that combine mathematical modeling and algorithms for exascale simulations and data-intensive science with applications in the fields of Computational Fluid Dynamics, Computational Biology and Particle and Nuclear Physics with focus in lattice Quantum Chromodynamics. Students will be seconded to industrial partners that will complement expertise in computer technologies, mathematical modeling and data analytics with hands-on training. Experts from eight degree-awarding institutions, three research centers and three companies are engaged in the project. Each of the fifteen fellows of the program will obtain a single joint Ph.D. degree from three academic institutions.;3755601;3755601;H2020-MSCA-ITN-2017;/MSCA-ITN-EJD;THE CYPRUS INSTITUTE;CY;"UNIVERSITA DEGLI STUDI DI ROMA TOR VERGATA;RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN;BERGISCHE UNIVERSITAET WUPPERTAL;HUMBOLDT-UNIVERSITAET ZU BERLIN;THE HEBREW UNIVERSITY OF JERUSALEM;UNIVERSITY OF CYPRUS;UNIVERSITA DEGLI STUDI DI FERRARA";"IT;DE;IL;CY";;1;0;0;1;0;0 211730;764636;ProTechTion;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2017;H2020;Industrial decision-making on complex production technologies supported by simulation-based engineering;2018-03-01;2022-02-28;;"Simulation-based engineering (SBE), in which traditional R&D, design and production technologies are complemented with computer simulations, has revolutionized the industrial sector. Computer simulations are critical for control of manufacturing processes, non-destructive-testing and decision-making at production phases, and shorten the lead-time of design and development processes, thus reducing both costs and time-to-market. The overarching objective of ProTechTion is to harness the full potential of multi-disciplinary SBE technology in industrial environments concerned with complex production processes. To this purpose, ProTechTion will form a multi-disciplinary research and education network that unites relevant disciplines and stakeholders to (i) develop new computational paradigms, (ii) train a generation of ESRs in state-of-the-art SBE technologies and cross-disciplinary skills, and (iii) bridge the knowledge transfer gap in multi-disciplinary SBE. The main objective of ProTechTion translates into the following research and training objectives: • To train and empower a generation of ESRs in developing, together with the industrial researchers, innovative solutions for pressing Industrial Problems (IPs). These solutions will be based on industry-driven tailor-made computational simulation tools. • To position European industry in the vanguard of SBE, and reinforce and consolidate Europe’s worldwide leadership. • To contribute with original research and innovations in SBE in order to solve multidisciplinary problems with interdisciplinary tools arising from the proposed IPs for fast decision making. • To cultivate the entrepreneurial spirit of the ESRs and integrate transverse research skills with demonstrators (codes).";3831509,88;3831509,88;H2020-MSCA-ITN-2017;/MSCA-ITN-EJD;CENTRE INTERNACIONAL DE METODES NUMERICS EN ENGINYERIA;ES;"SWANSEA UNIVERSITY;TECHNISCHE UNIVERSITAET MUENCHEN;ECOLE CENTRALE DE NANTES;UNIVERSITE LIBRE DE BRUXELLES;UNIVERSITA DEGLI STUDI DI PAVIA;TECHNISCHE UNIVERSITEIT EINDHOVEN;INSTITUTO SUPERIOR TECNICO";"UK;DE;FR;BE;IT;NL;PT";;1;0;0;1;0;0 211660;764840;IGNITE;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2017;H2020;Comparative genomics of non-model invertebrates;2018-01-01;2021-12-31;;Invertebrates, i.e., animals without a backbone, represent 95% of animal diversity on earth but are a surprisingly underexplored reservoir of genetic resources. The content and architecture of their genomes remain poorly known or understood, but such knowledge is needed to fully appreciate their evolutionary, ecological and socio--economic importance, as well as to leverage the benefits they can provide to human well-being, for example as a source for novel drugs and biomimetic materials. Europe is home to significant world-leading expertise in invertebrate genomics but research and training efforts are as yet uncoordinated. IGNITE will bundle this European excellence to train a new generation of scientists skilled in all aspects of invertebrate genomics. We will considerably enhance animal genome knowledge by generating and analysing novel data from undersampled invertebrate lineages and developing innovative new tools for high-quality genome assembly and analysis. Well-trained genomicists are in increasing demand in universities, research institutions, as well as in software, biomedical, and pharmaceutical companies. Through their excellent interdisciplinary and intersectoral training spanning from biology and geobiology to bioinformatics and computer science, our graduates will be in a prime position to take up leadership roles in both academia and industry in order to drive the complex changes needed to advance sustainability of our knowledge-based society and economy.;3810685,32;3810685,32;H2020-MSCA-ITN-2017;/MSCA-ITN-ETN;LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN;DE;"NATIONAL UNIVERSITY OF IRELAND GALWAY;FACULTY OF SCIENCE UNIVERSITY OF ZAGREB;EUROPEAN MOLECULAR BIOLOGY LABORATORY;GENERALDIREKTION DER STAATLICHE NATURWISSENSCHAFTLICHEN SAMMLUNGEN BAYERNS;HITS GGMBH;UNIVERSITE LIBRE DE BRUXELLES;Era7 Information Technologies SL;UNIVERSITY OF BRISTOL;CIIMAR - Centro Interdisciplinar de Investigaç?o Marinha e Ambiental;PENSOFT PUBLISHERS;INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE;UNIVERSITY COLLEGE LONDON;UNIVERSITETET I BERGEN";"IE;HR;DE;BE;ES;UK;PT;BG;FR;NO";;1;0;0;1;0;0 210971;741273;THUNDERR;SIGNED;H2020-EU.1.1.;ERC-2016-ADG;H2020;Detection, simulation, modelling and loading of thunderstorm outflows to design wind-safer and cost-efficient structures;2017-09-01;2022-08-31;;"Wind actions are crucial for the safety and cost of structures. The wind climate of Europe and many parts of the world is dominated by synoptic extra-tropical cyclones and mesoscale thunderstorm outflows. Thunderstorms are frequent events causing wind speeds often higher than cyclones. In spite of an impressive amount of research, there is not yet a model for thunderstorm outflows and their actions on structures like that for cyclones. Thus, thunderstorm actions on structures are still determined using the cyclone model developed half a century ago and engineering practice often leads to unsafe or too expensive construction. This happens because the complexity of thunderstorms makes it difficult to develop realistic and simple models. Their short duration and small size make the available data very poor. There is a great gap between research in wind engineering and atmospheric sciences. The realization of an unprecedented wind monitoring network, the role of the PI and his novel vision, a project team leader in wind engineering with interdisciplinary skill in atmospheric sciences, the chance to simulate large-scale thunderstorms in a new unique laboratory, the recent advance in CFD simulations, the success and synergy of previous and on-going projects, and a top host institution represent extraordinary conditions to overcome these shortcomings. THUNDERR is an acronym of THUNDERstorm that points out the ground-breaking Roar of this project. It aims to detect novel thunderstorm measurements, to create a huge dataset of field acquisitions and a new interpretation of their weather scenarios, to conduct unique wind tunnel tests and CFD analyses, to formulate a thunderstorm model that is physically correct and suitable to develop a loading scheme easily transferable to engineering and codification, to radically change the existing wind loading format and the engineering practice, to design safer and cost-efficient structures producing a deep social and economic impact.";2396643,75;2396643,75;ERC-2016-ADG;/ERC-ADG;UNIVERSITA DEGLI STUDI DI GENOVA;IT;;;;1;0;0;1;0;0 211436;763747;CHAMPP;SIGNED;H2020-EU.4.a.;WIDESPREAD-04-2017;H2020;Czech Hamburg Advanced Medical and Photonics Project;2017-09-01;2018-08-31;;"The proposed Teaming action will enable us to transform ELI-Beamlines into the “CHAMPP” Centre of Excellence (CoE) with worldwide unique and unprecedented opportunities - both for the scientific communities and the grand goal of promoting the innovation performance level of the Czech Republic. In case the present proposal under H2020 should be successfully assessed, the Czech Ministry for Education Youth and Sport has committed itself to add substantial additional funding from the Czech Republic’s Operational program for Research Development and Education (OP RDE). Both funds will be targeted in the following key areas: • offering the next-generation of brilliant X-ray sources to science and industry as a user facility i.e. • the world’s first laser-driven, ultra-compact Free-Electron Laser (FEL) as well as • a laser-based medical imaging beamline for novel early tumour diagnostics and pharmacokinetics. The key measure is the Teaming with DESY and the University of Hamburg (UHH). DESY is one of the world-leading large-scale accelerator and FEL user facilities with a long-standing experience in generating and managing very big international user communities and user operation with an impressive track record in scientific publications and patents. UHH is world-leading in the field of laser-driven electron and photon sources, and has a profound experience in interdisciplinary research and education. The Teaming will build on the on the current UHH-ELI-Beamlines LUX project located at DESY and initiated in 2012. The overall project will be led by the Institute of Physics (IoP) in the Czech Republic with high level representatives of each partner on the Project Management board to ensure a sustainable strategic partnership.";400000;400000;H2020-WIDESPREAD-04-2017-TeamingPhase1;/CSA;FYZIKALNI USTAV AV CR V.V.I;CZ;"UNIVERSITAET HAMBURG;STIFTUNG DEUTSCHES ELEKTRONEN-SYNCHROTRON DESY";DE;;1;0;0;1;0;0 211325;724824;scAssembly;SIGNED;H2020-EU.1.1.;ERC-2016-COG;H2020;Algorithms and experimental tools for integrating very large-scale single cell genomics data;2017-12-01;2022-11-30;;Robust and flexible tissue- and cell-type specific gene regulation is a definitive prerequisite for complex function in any multi-cellular organism. Modern genomics and epigenomics provide us with catalogues of gene regulatory elements and maps illustrating their activity in different tissues. Nevertheless, we are far from being able to explain emergence and maintenance of cellular states from such data, partly because we so far lacked characterization of individual molecular states and genome control mechanisms at their native resolution - the single cell. Recently, new approaches developed by the single cell genomics community, with several contributions from our group, allow massive acquisition of data on the transcriptional, epigenomic and chromosomal conformation states in large cohorts of single cells. In this research program, we aim to move forward rapidly to bridge a major gap between these experimental breakthroughs and models of genome regulation in complex tissues. We will develop algorithms and models for representing data the transcriptional profiles, DNA methylation landscapes and Hi-C maps of literally millions of cells. Our tools will be designed specifically to leverage on new single cell RNA-seq, single cell Hi-C, single cell capture-pBat and higher order 4C-seq that we will continue to develop experimentally. Furthermore, we shall enhance and optimize our interdisciplinary framework hand in hand with a working model aiming at unprecedentedly comprehensive single cell analysis of E8-E10 mouse embryos. This will provide us with hundreds of worked-out cases of tissue specific gene regulation. The techniques and insights from these studies will then be used to characterize cell type aberrations and epigenetic reprogramming in tumors. The open algorithms, techniques and methodology we shall develop can accelerate research in multiple groups that will utilize single cell genomics to study numerous questions on gene regulation in the coming years.;2437500;2437500;ERC-2016-COG;/ERC-COG;WEIZMANN INSTITUTE OF SCIENCE LTD;IL;;;;1;0;0;1;0;0 211460;768692;ECCO;SIGNED;H2020-EU.2.1.5.3.;SPIRE-09-2017;H2020;Energy Efficient Coil Coating Process;2017-10-01;2021-09-30;;Coil coating is an important industrial process applied in a major part of industrial steel and metal alloy production and associated with big facilities and large primary energy consumption. A major part of the overall plant size and the energy demand of coil coating facilities is associated with the drying/curing process that occur inside a curing oven, which is the bottleneck concerning the increase of the production capacity. In this drying/curing process, organic solvents are vaporized from the applied liquid coating film and since they are flammable, the usually applied curing ovens with convective air drying technology have to be operated far below the Low Explosive Limit (LEL), due to safety constraints. ECCO proposes a novel solution for the curing oven operation, which can not only drastically increase the compactness and energetic efficiency of the system, but leads to an increased production flexibility due to a fuel-flexible, modular and potentially energetically self-sustainable process. The main idea is to heat the metal strip by IR-radiation and operate the curing oven well above the Upper Explosive Limit (UEL), thus, performing the drying and curing process in an atmosphere mainly consisting of the solvent vapours, which are used as fuel in IR radiant porous burners. This solution leads to a size/ production capacity ratio reduction of 70% and a reduction of investment and operating costs of at least 40% each. Starting from previous activities at TRL 4, an interdisciplinary approach is foreseen, based on advanced-materials, combustion technology and prediction tools for system design/optimization, with active participation of key industrial stakeholders, to bring this technology to TRL 6 and realize a prototype furnace at industrially relevant size and environment.;9803316,25;7850029,38;H2020-SPIRE-2017;/IA;KARLSRUHER INSTITUT FUER TECHNOLOGIE;DE;"NATIONAL TECHNICAL UNIVERSITY OF ATHENS - NTUA;GoGaS Goch GmbH & Co. KG;GLOBUS SRL;FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA;European Research Institute of Catalysis A.I.S.B.L.;ENGICER SA;AKZO NOBEL INDUSTRIAL COATINGS AB;SCUOLA UNIVERSITARIA PROFESSIONALE DELLA SVIZZERA ITALIANA;COLOROBBIA CONSULTING SRL;INSTITUTO SUPERIOR TECNICO;THYSSENKRUPP STEEL EUROPE AG";"EL;DE;IT;BE;CH;SE;PT";;1;0;0;1;0;0 210473;724821;ThymusTolerance;SIGNED;H2020-EU.1.1.;ERC-2016-COG;H2020;Delineation of molecular mechanisms underlying the establishment and breakdown of immunological tolerance in the thymus;2017-09-01;2022-08-31;;"Central tolerance is shaped in the thymus, a primary lymphoid organ, where immature T lymphocytes are “educated” into mature cells, capable of recognizing foreign antigens, while tolerating the body’s own components. This process is driven mainly by two separate lineages of thymic epithelial cells (TECs), the cortical (cTEC) and the medullary (mTEC). While cTECs are critical at the early stages of T cell development, mTECs play a pivotal role in negative selection of self-reactive thymocytes and the generation of Foxp3\ regulatory T (Treg) cells. Crucial to the key role of mTECs in the screening of self-reactive T cell clones, is their unique capacity to promiscuously express and present almost all self-antigens, including thousands of tissue-specific antigen (TSA) genes. Strikingly, the expression of most of this TSA repertoire in mTECs is regulated by a single transcriptional regulator called Aire. Indeed, Aire deficiency in mice and human patients results to multi-organ autoimmunity. Although there has been dramatic progress in our understanding of how thymic epithelial cells shape and govern the establishment of adaptive immunity and of immunological self-tolerance, there are still several outstanding questions with no comprehensive answers. Therefore, in the research proposed herein, we wish to provide more comprehensive answers to these still elusive, but very fundamental questions. Specifically we will aim at: 1.) Delineation of molecular mechanisms controlling TEC development and thymus organogenesis; 2.) Delineation of molecular mechanisms underlying promiscuous gene expression in the thymus; 3.) Identification and characterization of molecular determinants responsible for the breakdown of thymus-dependent self-tolerance. To this end, we will build upon our recently published data, as well as unpublished preliminary data and utilize several state-of-the-art and interdisciplinary approaches, which have become an integral part of our lab’s toolbox.";2220000;2220000;ERC-2016-COG;/ERC-COG;WEIZMANN INSTITUTE OF SCIENCE LTD;IL;;;;1;0;0;1;0;0 209683;753597;SARSESNA;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Sustaining A Regional Screen Ecosystem In A Small Nation: Aarhus and the West Danish Film Fund, 2002-2019;2018-05-01;2020-04-30;;Since 2010 Danish screen production has enjoyed international attention with the popularity of high-quality films and TV series. Yet these emerge from a specific culture-political milieu that is concentrated in the capital Copenhagen. Current research on Danish production is similarly Copenhagen-centric. This imbalance means that peripheral regions of Denmark like Aarhus are neglected and underdeveloped as production hubs. This project addresses the question of how regional screen industries of small nations can be sustained and strengthened by examining the site-specific activities of the West Danish Film Fund (DVF) and its collaborations with the Aarhus 2017 EU Capital of Culture project. My main objectives are to 1) produce a 'deep map' of the regional screen ecosystem in Aarhus, 2) identify the implications of new funding and support initiatives, and 3) outline strategies on how regional screen production can productively harness geography, heritage, and tourism to strengthen domestic and international ties. I utilise a combination of qualitative and quantitative methodologies in screen studies to achieve these goals. Through a 4-week secondment at DVF and close links between Aarhus University (AU) and industry players, I will interview screen practitioners and policymakers across the region, examine policy and funding practices, analyse quantitative data relating to production and distribution, and evaluate industry innovations. This project includes both transfer of knowledge to AU and the training of the candidate in advanced techniques. This interdisciplinary research will be the first to significantly deepen knowledge on the regional screen industry of Aarhus and provide policy advice, build networks, concepts and tools on how to sustain the regional screen milieu. Results will have strong applicability to other Capitals of Culture and EU regions, enhancing understanding of how regional screen industries balance national cultural policy with local identity.;212194,8;212194,8;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;AARHUS UNIVERSITET;DK;;;;1;0;0;1;0;0 209321;750169;SELFCONTROLHEALTH;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Childhood Self-Control, Social Conditions, and Adult Health;2018-03-15;2020-03-14;;The capacity to delay gratification and control impulses emerges in childhood and may profoundly shape the lifestyle behaviours and resulting health conditions that afflict many and burden health systems across Europe and rest of the world. Childhood self-control appears to be malleable and as such has been identified by policy-makers as a key prevention target with potential long-run benefits. Yet, empirical evidence demonstrating links from early self-control to adult outcomes remains scarce. This Fellowship will inform estimates of the benefits of fostering self-control by drawing on under-exploited childhood self-control measures from six pre-existing large scale (N>1,000) prospective studies of individuals whose health behaviour and health has been tracked for up to 55 years. Already, using these incredible resources the applicant has identified how childhood self-control predicts population patterns of smoking and weight gain across life. He now aims to advance this work and the scientific literature by identifying: (i) the specific life-span health consequences of early self-control (e.g. biomarkers, chronic conditions, mortality rates), (ii) the key behavioural and socioeconomic pathways that explain these linkages, and (iii) the social conditions where self-control may have the greatest health impact. The Fellowship will both enrich and benefit from the strengths of the host institution in Childhood and Human Development research. Strong input from a world-leading researcher in this area, Prof. Richard Tremblay, will help enable the applicant to make a disciplinary shift from behavioural medicine to an integrated life-course perspective where adult health is viewed through the lens of child development. This interdisciplinary mobility coupled with a strong programme of advanced training will ensure the Fellowship rapidly advances both the applicant’s career development and the exciting programme of work outlined in this proposal.;187866;187866;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN;IE;;;;1;0;0;1;0;0 209724;724275;BantuFirst;SIGNED;H2020-EU.1.1.;ERC-2016-COG;H2020;The First Bantu Speakers South of the Rainforest: A Cross-Disciplinary Approach to Human Migration, Language Spread, Climate Change and Early Farming in Late Holocene Central Africa;2018-01-01;2022-12-31;;The Bantu Expansion is not only the main linguistic, cultural and demographic process in Late Holocene Africa. It is also one of the most controversial issues in African History that still has political repercussions today. It has sparked debate across the disciplines and far beyond Africanist circles in an attempt to understand how the young Bantu language family (ca. 5000 years) could spread over large parts of Central, Eastern and Southern Africa. This massive dispersal is commonly seen as the result of a single migratory macro-event driven by agriculture, but many questions about the movement and subsistence of ancestral Bantu speakers are still open. They can only be answered through real interdisciplinary collaboration. This project will unite researchers with outstanding expertise in African archaeology, archaeobotany and historical linguistics to form a unique cross-disciplinary team that will shed new light on the first Bantu-speaking village communities south of the rainforest. Fieldwork is planned in parts of the Democratic Republic of Congo, the Republic of Congo and Angola that are terra incognita for archaeologists to determine the timing, location and archaeological signature of the earliest villagers and to establish how they interacted with autochthonous hunter-gatherers. Special attention will be paid to archaeobotanical and palaeoenvironmental data to get an idea of their subsistence, diet and habitat. Historical linguistics will be pushed beyond the boundaries of vocabulary-based phylogenetics and open new pathways in lexical reconstruction, especially regarding subsistence and land use of early Bantu speakers. Through interuniversity collaboration archaeozoological, palaeoenvironmental and genetic data and phylogenetic modelling will be brought into the cross-disciplinary approach to acquire a new holistic view on the interconnections between human migration, language spread, climate change and early farming in Late Holocene Central Africa.;1997500;1997500;ERC-2016-COG;/ERC-COG;UNIVERSITEIT GENT;BE;MUSEE ROYAL DE L'AFRIQUE CENTRALE;BE;;1;0;0;1;0;0 208568;745676;qBioNano;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Quantifying bio-nano interactions of nanoparticles through microfluidic live cell Raman spectroscopy;2017-08-21;2019-08-20;;As a Marie Sk³odowska-Curie Fellow in “qBioNano: Quantifying bio-nano interactions of nanoparticles through microfluidic live cell Raman spectroscopy”, I will combine three emerging fields—layer-by-layer (LbL) assembly of nanoparticles (NPs), microfluidics, and live cell Raman spectroscopy (RS)—to enable 3D imaging and quantification of how NPs and cells interact under physiological conditions. This will allow, for the first time, non-invasive, non-destructive, label-free, spatiotemporally resolved study of a range of biomolecules (e.g., lipids and proteins) and biostructures (e.g., nuclei and mitochondria) at the same time as LbL assembled NPs to answer long-standing questions on particle-induced changes in cellular states and processes. The NPs will be produced through LbL assembly of alkyne-containing polymers (having Raman spectra clearly visible in biological environments), and—using microfluidic devices (where cells can be introduced and maintained in physiologically relevant environments)—I will study how these NPs affect both healthy and diseased cells and tissues (e.g., at cell-cell interfaces and using spheroids). This project will provide: (i) the first detailed view into the biology underlying cellular responses to LbL assembled NPs under physiological conditions, and (ii) a new platform offering insight into key cellular processes and responses governing how cells and tissues interact with, and respond to, engineered NPs. By combining my expertise in developing NPs, microfluidic systems and investigating bio-nano interactions, with the supervision of Prof. Molly Stevens at Imperial College London (ICL), who runs a world-class interdisciplinary biomaterials group with extensive experience in RS, materials science, and cell and tissue biology, this project is uniquely situated to address these urgent—but challenging—topics and deliver the highest quality results.;195454,8;195454,8;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE;UK;;;;1;0;0;1;0;0 210501;727922;DELTA-FLU;SIGNED;H2020-EU.3.2.1.1.;SFS-14-2016;H2020;Dynamics of avian influenza in a changing world;2017-06-01;2022-05-31;https://delta-flu.fli.de/;DELTA-FLU aims to determine the key viral, host-related, and environmental factors that determine the dynamics of avian influenza (AI) in poultry and other host species, with the goal of improving prevention and control strategies against this disease. As a result of rapidly changing dynamics, AI continues to cause unexpected and devastating outbreaks in poultry in the EU, as well as world-wide. Its potential to become pandemic is also of great concern to public health. The key viral, host-related, and environmental factors that drive AI dynamics are poorly understood, which currently impedes the development of effective control and prevention strategies. As the problems caused by AI require global solutions, DELTA-FLU is a consortium with top-level experts from Europe, North America, and Asia. Through interdisciplinary research focused on key questions of AI, DELTA-FLU will determine 1) potential for some highly pathogenic avian influenza viruses (HPAIV, e.g. H5N8 clade 2.3.4.4) to be maintained in wild bird populations and spread over long-distances, 2) key viral, host, and environmental factors for incursion of HPAIV from wild birds into poultry holdings, 3) roles of viral, host, and environmental factors in the transition of low pathogenic avian influenza virus to HPAIV in poultry, 4) effect of flock immunity against AI on early detection and viral genetic drift, and 5) viral genetic factors that allow reassortants of avian and mammalian influenza viruses to transmit efficiently among pigs. Primary sectors and end-users are involved through participation in the Multi-Actor Panel, which will also play an important role in the translation of the results into effective prevention and control strategies. As such, DELTA-FLU will make significant advances in knowledge of AIV dynamics and provide the evidence base for improved diagnosis, prevention, and control strategies for AI in poultry, as well as for reducing the possible risk of AI to become potentially pandemic.;5497793,75;5497793,75;H2020-SFS-2016-2;/RIA;FRIEDRICH LOEFFLER INSTITUT - BUNDESFORSCHUNGSINSTITUT FUER TIERGESUNDHEIT;DE;"LINNEUNIVERSITETET;THE SECRETARY OF STATE FOR ENVIRONMENT, FOOD AND RURAL AFFAIRS;UNIVERSITEIT GENT;UNITED STATES DEPARTMENT OF AGRICULTURE;ISTITUTO ZOOPROFILATTICO SPERIMENTALE DELLE VENEZIE;THE UNIVERSITY OF HONG KONG;ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM;THE UNIVERSITY OF EDINBURGH";"SE;UK;BE;US;IT;HK;NL";;1;0;0;1;0;0 209625;750871;HGRF-IFIC;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Commissioning, first tests and upgrade of a high-power S-Band Radio Frequency (RF) system for R+D of high-gradient normal-conducting accelerating cavities in breakdown science and RF conditioning;2017-05-19;2019-05-18;;"New Radio Frequency (RF) High-Gradient (HG) knowledge and technology in normal conducting accelerator structures has been developed by the accelerator Physics community in the recent years in X-Band frequency. Significant progress has been made to understand the RF high-gradient behavior, breakdown phenomena and cavities conditioning processes, but extensive R&D is still needed in this very interdisciplinary and phenomenology research area. This project proposes the commissioning and upgrade of a novel high-power RF system in S-Band to perform systematic breakdown studies and conditioning of cavities in this frequency range, in particular interesting for medical applications. The main challenge is the implementation of a hard real-time control of amplitude and phase at microsecond scale of the pulsed megawatt RF power delivered to the structures under test. The power delivery has to be done under stringent controlled and automated conditions in order to perform the conditioning and avoid permanent damage to the structures. In addition, a power boost upgrade of the system is envisaged to reach the power limits that medical high-gradient structures need to be pushed to. A close relation with industry partners is to be carried out in order to commission the new solid-state power modulator and test structures. The outcome of this R&D project can be crucial to make more compact linear accelerators, resulting in lower cost and size, which can have a potential impact in several applications: hadrontherapy facilities based on linear accelerators, which will be emphasized in this project due to its advantageous features; industrial applications such as cargo scanning; or scientific applications such as free-electron-lasers and Compton sources.";170121,6;170121,6;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;UNIVERSITAT DE VALENCIA;ES;;;;1;0;0;1;0;0 209771;746614;CAD WALK;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;CAD WALK: Enabling Computer Aided Diagnosis of Foot Pathologies through the use of Metric Learning;2017-10-01;2019-09-30;;"Dynamic plantar pressure imaging (PPI) refers to the measuring, across time, of pressure fields between the foot and the ground. PPI is used, in part, to diagnose foot problems such as metatarsalgia and plantar fasciitis. Despite the widespread clinical use of PPI, its diagnostic potential has not been fully exploited. PPI creates large and dynamic datasets that cannot be easily analysed and interpreted by the human brain. As a result, PPI images are subsampled before being clinically examined, which discards potentially valuable information. The objective for this action is to improve the diagnostic value of PPI through the introduction of a computer-aided diagnosis (CAD) system called CAD WALK. Using concepts from my previous CAD research (STEAM), CAD WALK will build a statistical model of PPI images from a healthy population. To test a new patient, their PPI image will be aligned to the model and compared to that healthy population using statistical tests. Outliers from these statistical tests will then be highlighted to help guide a clinician’s examination of the full PPI image. As a novel addition, metric learning will be introduced to create a statistical model that is more specific to the test subject. A key goal of this action is the deployment of CAD WALK as a supported software product. To do so, we propose a Triple ‘i’ (international, intersectoral, interdisciplinary) initiative that partners me with industry (rs scan®) and clinical end users (Sint Maartenskliniek, NL) to translate my CAD research into practical use. Through this process, and a secondment with industry partner rs scan®, I expect to deepen my knowledge of industrial product development (i.e. intellectual property rights, industry regulations, customer constraints) and improve my management skills. By addressing these two gaps in my career experience, I expect to move one step closer to fulfilling my ambition of leading my own research translation lab.";160800;160800;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;UNIVERSITEIT ANTWERPEN;BE;;;;1;0;0;1;0;0 209617;750348;CPR;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;A cross-country comparison of Communications designed to Prevent Radicalisation;2017-11-01;2019-10-31;;The CPR project (A cross-country comparison of Communications designed to Prevent Radicalisation) analyses communications in the UK and Denmark that are designed to contribute to the prevention of vulnerable individuals being radicalised by terrorist groups such as ISIL. CPR will make a significant contribution to a problem facing many European states – namely how to effectively utilise strategic communications to counter terrorist propaganda. It is widely recognised in the literature that, to date, Western states have not been sufficiently effective in their counter-radicalisation communication strategies. It is unclear what a more prioritised communicative approach will mean in practice and communication efforts lack coordination between and, often, within countries to date. By employing an interdisciplinary theoretical approach and utilising unique access to new primary data in both states, CPR will, across four specific research strands, make three major contributions: i) generate a deeper and more nuanced empirical and conceptual understanding of the effectiveness of current counter-terrorism communications targeted at a range of audiences, ii) provide an empirically unique analysis of the challenges to effective prevention communications and, iii) provide empirically substantiated and theoretically informed communications-focused policy requirements that will improve the ability of practitioners and policy-makers to design and deliver communications that contribute to the prevention of radicalisation. CPR will employ a mixed methods methodology, incorporating semi-structured interviews for qualitative analysis alongside online surveys experiments to identify key quantative insights derived from new primary data. The project multi-actor and multi-level analysis in CPR moves beyond the state of the art in terms of methods and theory, access to data, and addressing new and broader questions in an under explored, and empirically lacking, area of research.;200194,8;200194,8;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;AARHUS UNIVERSITET;DK;;;;1;0;0;1;0;0 209645;751865;MalariaEgress;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Role of perforin-like proteins and phospholipases in malaria parasite egress;2018-01-01;2020-01-07;;The malaria parasite Plasmodium falciparum, which causes ~600,000 deaths annually, propagates within host erythrocytes. Roughly synchronous egress of blood stage parasites in vivo causes the periodic fevers associated with malaria and is essential for parasite replication. Blocking parasite egress can stop disease progression, so understanding its mechanism is key to identifying new drug targets. Egress of malaria parasites from host erythrocytes involves the rupture of two membranes- the parasitophorous vacuole membrane and the erythrocyte membrane. It is unclear how the parasitophorous vacuole membrane ruptures during egress, and what mechanism is responsible for poration of the erythrocyte membrane. While it has been shown that egress is protease-dependent, the effector molecules that bring about the disruption of both membranes remain unknown. Potential effector molecules include parasite perforin-like proteins (PLPs) and phospholipases. This project aims to test the hypothesis that Plasmodium PLPs and phospholipases are involved in malarial egress. First, we will apply newly developed conditional knockout strategies to establish the role in egress of a candidate perforin-like protein. Second, we aim to devise a novel conditional genetic screen to identify egress related phospholipases in a medium-throughput manner. This work will add to the efforts being made to understand egress and will attempt to develop a much needed forward genetic screen in the malaria parasite. The interdisciplinary approach proposed here combines the experienced researcher (ER)’s skills in genomics and the host laboratory’s expertise in malarial cell biology and conditional knockout technologies. This will equip the ER with the right exposure and new skills to pursue a future independent research career in malaria research.;183454,8;183454,8;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;THE FRANCIS CRICK INSTITUTE LIMITED;UK;;;;1;0;0;1;0;0 208945;748452;Justhood;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;(Un)Just NeighbourhoodsSocio-Spatial Justice in Urban Neighbourhoods;2018-01-10;2021-01-09;;"Rapid urbanisation, growing process of globalisation, and the neoliberal hegemony have culminated in the omnipresence of socio-spatial inequalities at the neighbourhood scale regarding racial segregation, deprivation, stigmatisation, and degradation. European and North American cities, among others, have initiated neighbourhood-oriented urban redevelopment schemes to mitigate the burden of urban injustice. However, there is no integrated framework to evaluate their achievements, the contribution of urban neighbourhoods to just cities has not been systematically investigated. To address this lacuna, the project conceptualises the idea of (un)just neighbourhoods from socio-spatial justice perspective and develops an evaluation framework for measuring key qualities of socio-spatial justice at the neighbourhood scale. The project employs a methodological bricolage approach to address its interdisciplinary nature. It first theorises (un)just neighbourhoods from two perspectives of intra-neighbourhood and inter-neighbourhood socio-spatial justice. It then proposes an integrated framework, consisting of a set of principles, indicators, and measures, for evaluating neighbourhood-oriented redevelopment schemes. Focusing on two neighbourhoods of Bayview-Hunters Point (San Francisco) and Fruitvale (Oakland), the research critically reflects on the constructed storytelling around socio-spatial justice imposed by the local authorities. The proposed evaluation framework is applied to the case study neighbourhoods through intensive fieldwork to explore whether and to what extent the implemented redevelopment schemes have enhanced socio-spatial justice of the neighbourhoods, or re-produced existing socio-spatial injustice, in both process of interventions and their outcomes. Finally, using recent achievements in digital ethnography, the project documents alternative paths and stories towards achieving greater urban justice practiced by the community coalitions and grassroots.";269857,8;269857,8;H2020-MSCA-IF-2016;/MSCA-IF-GF;OXFORD BROOKES UNIVERSITY;UK;;;;1;0;0;1;0;0 209242;747160;CoMiC;TERMINATED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Cold Molecules in Cavities;2017-07-01;2019-06-30;;"Here we propose a radically new way to control chemical reactions on the quantum level. The Experienced Researcher (ER) will combine his long-standing expertise on cavity quantum electrodynamics (CQED) with the field of ultracold chemical reactions, in which the host is one of the leading pioneers. We want to drive a photo-chemical reaction (photoassociation) within an optical cavity and in this way gain control over the reaction (objective 1). For this, we use the control over spontaneous photon emission by an optical cavity, as has been done with single atoms. This paves the way towards novel fascinating effects like superradiant chemistry, where a chemical process is enhanced due to quantum statistics. Furthermore, the optical cavity will be used as an ultrasensitive molecule detector of a new quality by detecting them without disturbing their quantum state (objective 2). This novel interdisciplinary combination of physics and chemistry will open up a new research field, where the ER will demonstrate scientific innovation and independence.";159460,8;159460,8;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;UNIVERSITAET ULM;DE;;;;1;0;0;1;0;0 209614;750242;MOOC_DaSI;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Patterns of diffusion and social implications of Massive Open Online Courses (MOOCs): A comparative study between United States and Europe;2017-10-01;2019-09-30;;"The MOOC_DaSI project aims to develop a comparative study between the United States and Europe investigating patterns of diffusion of Massive Open Online Courses (MOOCs) and their contribution to a “smart ad inclusive growth” through: a) broadening access to education and b) providing individuals with better skills. MOOCs have been pointed out as a flexible, customized, cost-effective type of education that may play a key role in the future of higher education. However, the outburst of MOOCs also brought about contrasting arguments and so far empirical research is limited and fragmented. The project will contribute to shed light on this topic investigating two main research questions. The first deals with the organizational aspects of MOOCs diffusion and will explore whether a “European way” to MOOCs can be identified. The second investigates whether MOOCs do contribute in reducing social inequality by a) broadening access to higher education to non-traditional and socio-economically disadvantaged students; b) providing returns on the labour market. Finally, the research project will summarize a series of policy recommendations providing policy-makers with empirical ground for designing effective policies in the context of open educational resources. MOOC_DaSI will adopt an interdisciplinary approach spanning between organizational studies, sociology of education and stratification research. The project will also make use of mixed methods of research, combining qualitative and quantitative data and different methods of analysis. The MOOC_DaSI project will be carried out at the University of Turin (IT) and Stanford University (USA) over a period of 24 months, including a secondment period at the EC-JRC in Seville (ES). The implementation of the project will contribute to enhance the fellow’s expertise and thus the chances to reach her career objectives of establishing an own research group and obtaining future grants for large international projects.";176203,8;176203,8;H2020-MSCA-IF-2016;/MSCA-IF-GF;UNIVERSITA DEGLI STUDI DI TORINO;IT;;;;1;0;0;1;0;0 209314;749965;RoyalCities;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;The King’s City: A Comparative Study of Royal Patronage in Assur, Nineveh, and Babylon in the First Millennium BCE;2018-09-01;2020-08-31;;Cities first developed in the fourth millennium BCE in Mesopotamia and quickly became the centers of civilization. Despite extensive work on urban landscapes from an archaeological perspective, these ancient cities remain poorly understood. Even less studied are royal capitals, the seats of kingship when empires emerged in the first millennium BCE. This project explores capitals from the two main, competing empires—Neo-Assyrian and Neo-Babylonian—to address key questions: what constitutes a royal capital and what distinguishes it from other important cities? How are capitals conceptualized by the kings who inhabit, establish, and renovate them? What are the effects of the kings’ presence in and patronage of the capital cities on the urban fabric and the social and economic structure of the urban population? By juxtaposing the Assyrian capitals in Assur and Nineveh with the Babylonian capital of Babylon as case studies, this research uses a novel comparative approach based on a methodology that combines philology, religious studies, and social and political history to answer these questions. Uniting materials from the highest levels of state such as royal inscriptions, decrees, and letters with administrative, economic, and private archives, and joining these textual records with archaeological evidence through the lens of royal patronage, this project employs an innovative holistic and interdisciplinary framework to reveal how the kings’ ideological and official relationships to their capitals affects the social and bureaucratic structures of these cities. The project capitalizes on the knowledge transfer between the researcher’s Neo-Assyrian specialty and the host institution’s Neo-Babylonian expertise. The project’s results have great potential to revolutionize our understanding of cities and royal power in the ancient world, and to make accessible a wealth of new data for fields as diverse as history, anthropology, sociology, urban studies, and political science.;166156,8;166156,8;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;UNIVERSITAT WIEN;AT;;;;1;0;0;1;0;0 209493;725046;TIMING;SIGNED;H2020-EU.1.1.;ERC-2016-COG;H2020;Time-Resolved Nonlinear Ghost Imaging;2017-06-01;2022-05-31;;"This project addresses major challenges in Terahertz (THz) sensing at the forefront of the experimental and theoretical investigation. The results will have far-reaching implications in complex science. They will target the next generation of THz imagers, acknowledged as unique diagnostic tools in cross-disciplinary fields in light of the THz’s distinctive ability to unambiguously discriminate molecular compounds. The project objectives are: (i) to explore the consequences of modern approaches to imaging with structured illumination in the THz domain. (ii) to introduce a novel approach to THz microscopy. TIMING will explore a novel form of single-pixel imaging that boosts the performance of the state-of-the-art. It exploits concepts cross-disciplinary inherited from fields like complexity and nonlinear-physics. The newly developed background will directly impact transverse fields like acoustic, microwaves and optics where related forms of imaging are strongly investigated. The sought results aim to enable applications in several scenarios in biology, medicine, material science, quality inspection and security. In all those fields, active THz imaging is still challenged by the poor general resolution, low brightness and relatively long acquisition time, aspects directly targeted by this project. TIMING is at the same time a project and novel imaging concept that will unveil real applications in transversal and interdisciplinary fields where imaging and material discrimination are strategic.";1979270;1979270;ERC-2016-COG;/ERC-COG;THE UNIVERSITY OF SUSSEX;UK;;;;1;0;0;1;0;0 210211;740543;MINDb4ACT;SIGNED;"H2020-EU.3.7.6.;H2020-EU.3.7.1.";SEC-06-FCT-2016;H2020;Mapping, IdentifyiNg and Developing skills and opportunities in operating environments to co-create innovative, ethical and effective ACTions to tackle radicalization leading to violent extremism;2017-09-01;2020-08-31;;"'MINDb4ACT is a collaborative project participated by 7 LEAs, think-tanks, reserach centres, universities, industry associations and NGO based in 10 Member States (Austria, Belgium, Denmark, Finland, France, Germany, Italy, Poland, Spain and United Kingdom). The project will align its research priorities with some of the most relevant issues already identified by the European Commission: Priority 1. Systematizing the available knowledge and expertise to support strategic decision-making Priority 2. Enhancing interdisciplinary fieldwork on terrorists' recruiting grounds, socialisation and techniques Priority 3. Using big data in order to analyse the information related to the communication practices of violent radicalisation Priority 4.Improving existing links between academia including non-EU researchers, policy-makers and other stakeholders MINDb4ACT will contribute to such priorities for the improvement of current counter-violent extremism policies (CVEs) in the countries represented in the consortium (Austria, Belgium Denmark, Finland, France, Germany, Italy Poland, Spain and United Kingdom) and the generation of new ones connecting through collaboration ecosystems (innovative, open, participatory, user-centred environments) to co-design interventions such as research actions, exchanges, strategic-policy exercises, training courses and pilot projects based on social innovation and civic engagement schemes (a community of practice of 1,500 people). All actions will be developed in 5 specific domains: prisons and judiciary system; migration hotspots and asylum centres, schools, cities (peri-urban contexts) and the Internet and media. A special contribution of the project will be the integration of technology based practical solutions with the contribution of the industry. As mentioned in the call, MINDb4ACT will NOT be “focused on studying the phenomenon of radicalization' but focused on “developing policy recommendations and practical solutions for end-users' '";2999309,5;2999309,5;H2020-SEC-2016-2017-1;/RIA;FUNDACION REAL INSTITUTO ELCANO DE ESTUDIOS INTERNACIONALES Y ESTRATEGICOS;ES;"HOCHSCHULE FUR DEN OFFENTLICHEN DIENST IN BAYERN;FONDATION POUR LA RECHERCHE STRATEGIQUE;MINISTERO DELLA GIUSTIZIA;SYNYO GmbH;STOWARZYSZENIE POLSKA PLATFORMA BEZPIECZENSTWA WEWNETRZNEGO;VRIJE UNIVERSITEIT BRUSSEL;FRAUEN OHNE GRENZEN - WOMEN WITHOUTBORDERS/SAVE-SISTERS AGAINST VIOLENT EXTREMISM GEMEINNUTZIGER VEREIN;DANSK INSTITUT FOR INTERNATIONALE STUDIER;EUROPEAN ORGANISATION FOR SECURITY SCRL;AYUNTAMIENTO DE MADRID;SHEFFIELD HALLAM UNIVERSITY;KOMENDA WOJEWODZKA POLICJI W POZNANIU;MINISTERIO DEL INTERIOR;Police Service of Northern Ireland;POLIISIAMMATTIKORKEAKOULU;FONDAZIONE AGENFOR INTERNATIONAL;FREIE UNIVERSITAET BERLIN";"DE;FR;IT;AT;PL;BE;DK;ES;UK;FI";;1;0;0;1;0;0 208907;746980;FiTTeR;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Developing a Fibrosis Targeting and Tissue Reparative (FiTTeR) Therapy for the Infarcted Myocardium via an Injectable Functionalized Extracellular Matrix Hydrogel;2017-08-21;2019-08-20;;As a Marie Sk³odowska-Curie Fellow, I will develop, characterize, and determine the efficacy of a biomaterial platform to target pathologic fibrosis and promote tissue repair following myocardial infarction (MI). I have an ideal background and will perform well in this project based on my expertise in extracellular matrix (ECM) derived biomaterials, characterizing the immune response to biomaterials, and evaluating in vivo outcomes. The proposed system will consist of a protein fragment tethered to an injectable hydrogel. The hydrogel carrier will be composed of ECM, which has been shown to facilitate tissue repair processes by local modulation of immune cell phenotype . The cryptic protein fragment, recently isolated and recombinantly produced by the Stevens Group , has gained attention for its ability to regulate the onset of fibrosis by interfacing with cells to abrogate the release of matrix metalloproteinases (MMPs). No therapies currently exist to prevent or mitigate fibrosis. Developing a sophisticated delivery system for a cryptic protein fragment will enable the broad potential of targeting pathologic fibrosis to be realized. This system will be advantageous in simultaneously providing localized delivery, combined immunomodulatory and regulatory properties of the ECM and recombinant protein fragment, and sustained release of the protein fragment during degradation of the ECM hydrogel. The combination of my expertise (in ECM hydrogels, characterizing the host response to biomaterials, and translating technologies) and Prof Molly Stevens’s supervision and world-class interdisciplinary biomaterials-focused group, the 2014 Research Group of the Year (European Life Science Awards), at Imperial College London (ICL), together make this project ideally suited for success.;195454,8;195454,8;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE;UK;;;;1;0;0;1;0;0 209048;752097;OPN-Can;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Investigating the role of OPN-CD44 in mechanosensitive tumour invasion using biomimetic models;2017-09-04;2020-11-05;;"New fields are rapidly emerging that provide exciting and unforeseen opportunities to target disease. This is especially relevant for difficult-to-treat tumours where, despite decades of promising research, successful clinical translation of therapeutic options remains intractable. The interrelated fields of mechanobiology and biomimetic engineered disease models have come to the fore in the last decade1–3 and provide a range of opportunities to investigate therapeutic modalities4. These fields have implications for cancer research in three major aspects: 1) dissection of the cell biology governing microenvironmental sensing; 2) development of biomimetic platforms that enhance both the relevance (accuracy) of experimental models and our understanding of tumour biology, especially at the level of microenvironment and cell signalling; and 3) creation of analysis tools to quantify cell sensing. In this MSCA Global Fellowship, I propose a formative advanced research training period at one of the world’s leading institutions of cell and molecular biology and bioengineering (UCB) to learn and apply state-of-the-art biomimetic platforms for a novel tumour biology research project investigating osteopontin(OPN)-CD44 in mechanosensitive glioblastoma invasion. This interdisciplinary collaboration will match the expertise of UCB in biomimetic tumour invasion modelling of the biomechanical and biochemical properties of glioblastoma with my expertise in matricellular biology developed through my prior postdoctoral studies of osteopontin in liver disease. On my return to Europe at KCL, this will provide a springboard to establish an innovative independent research program in promising and underinvestigated tumour biology. I will transfer the knowledge learned at UCB to establish to investigate hepatocellular carcinoma invasion with biomimetic models. This work will ultimately benefit the development of anti-invasive adjuvant therapies.";251857,8;251857,8;H2020-MSCA-IF-2016;/MSCA-IF-GF;KING'S COLLEGE LONDON;UK;;;;1;0;0;1;0;0 210214;740580;VISAGE;SIGNED;"H2020-EU.3.7.1.;H2020-EU.3.7.7.";SEC-08-FCT-2016;H2020;Visible Attributes through Genomics: Broadened Forensic Use of DNA for Constructing Composite Sketches from Traces;2017-05-01;2021-04-30;;Unknown perpetrators of crime cannot be identified with the current forensic use of DNA. The VISAGE Project aims to overcome this major limitation by developing, validating, and implementing in the relevant forensic DNA service environment a set of prototype tools for predicting appearance, age, and ancestry in as much detail and as accurately, and effectively as possible from DNA traces. This VISAGE Toolkit will allow the construction of composite sketches of unknown trace donors directly from their crime scene traces, which will guide and focus criminal investigations towards finding them. The VISAGE Toolkit will include analysis prototype tools based on massively parallel sequencing for genotyping the large number of DNA predictors for appearance, age, and ancestry established within the Project, as well as an integrated statistical framework with prototype software for translating these genotype data into statistical probabilities on appearance, age and ancestry, which represents the intelligence information finally used for guiding criminal investigations towards the most probable group of suspects. The VISAGE Toolkit will consider ethical, societal, and legal dimensions of Forensic DNA Phenotyping as identified within the Project, by applying a privacy-by-design strategy. The interdisciplinary VISAGE Consortium includes European (and global) scientific leaders in Forensic DNA Phenotyping as well as in forensic massively parallel sequencing, leading European forensic DNA service providers, and one of the leading social scientists in the field of forensic DNA analysis, ensuring that the Project goals will be achieved on time. The outcome of the VISAGE Project will have a major impact on solving more crimes more rapidly by providing previously unused intelligence information from trace DNA to find unknown perpetrators, which will lead to reduced impact on victims, reduced societal distress, preventing miscarriages of justice, thereby avoiding unnecessary costs.;5007778,75;5000000;H2020-SEC-2016-2017-1;/RIA;ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM;NL;"KLINIKUM DER UNIVERSITAET ZU KOELN;INSTITUT NATIONAL DE POLICE SCIENTIFIQUE;MAYOR'S OFFICE FOR POLICING AND CRIME;UNIVERSIDAD DE SANTIAGO DE COMPOSTELA;BUNDESKRIMINALAMT;MEDIZINISCHE UNIVERSITAT INNSBRUCK;UNIVERSITAET ZU KOELN;POLISMYNDIGHETEN SWEDISH POLICE AUTHORITY;CENTRALNE LABORATORIUM KRYMINALISTYCZNE POLICJI;Netherlands Forensic Institute;KING'S COLLEGE LONDON;UNIWERSYTET JAGIELLONSKI";"DE;FR;UK;ES;AT;SE;PL;NL";;1;0;0;1;0;0 208876;745922;HRMN;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Human Rights, Memorialization and Nationalism;2017-09-01;2019-08-31;;"This research deals with the rise of memorialization standards and policy-oriented attempts to engage transitional societies to develop and adopt specific normative forms of remembrance. This project addresses one particular human rights assumption - that the standardization of memory enforced through memorialization policies is effective and necessary in promoting human rights values. Human rights advocates insist on memorialization as a crucial step in establishing moral responsibility for past atrocities understanding it as an insurance policy against the repetition of crimes. In nationalist ideologies, however, memory and memorialization is used for the sake of defining the “self” and the “other” through boundaries along ethnic lines. The project investigates the ways in which human rights advocates understand, promote and mandate supposedly universal memorialization standards, asking whether in so doing they weaken or instead often actually strengthen nationalism. Within the University College Dublin, School of Sociology, and under supervision of Prof Maleševiæ, a world-known expert in nationalism, the goal of this project is to get 1) new theoretical framework for the critical interdisciplinary study of human rights` memorialization policy; 2) new empirical insights into whether in different national contexts (in the Balkans and the Middle East) the prescribed standards of memory are being promoted, and if so, by whom and to what ends; 3) to develop case and gender-sensitive and cost-effective policy recommendations for future implementation of the EU human rights` memorialization policies. Successful realization of the project will enable Dr David to get a tenure track position at Hebrew University, where she will further use the acquired knowledge to search for innovative solutions to strengthen human rights.";187866;187866;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN;IE;;;;1;0;0;1;0;0 208889;746191;FIRESCAPE;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Firescape genomics: predicting plant responses to changing fire regimes;2018-01-01;2019-12-31;;Increases in the frequency of wildfire driven by invasive plant species, land use change and climate change are occurring globally. The current mismatch between past and present fire regimes means we have little ability to predict how, or if, ecosystems will adapt to these novel pressures. However, many European plant species have been introduced into Australia where fire frequency exceeds levels found in the species native range. My project, hosted by Trinity College Dublin and supervised by Professor Yvonne Buckley, will capitalise on this unique opportunity to predict how species will respond to increases in fire frequency that are occurring in Europe under climate change. I have already produced an existing genomic database from hundreds of individuals across fire frequency gradients in Australia. The task now is to strategically sample areas of Europe to establish the native baseline and use cutting-edge spatial analyses to investigate the phenotypic and genomic basis underlying adaptation to changing fire regimes in European plant species. My Training Plan includes specific professional development programs to enhance my critical skills in leadership, grant writing, teaching and global networking. During the fellowship, I will improve essential competencies needed to compete at ERC-level including mastering sophisticated analytical and bioinformatics tools. My interdisciplinary research, drawing together population ecology, invasive species management and landscape genomics will make a critical contribution to the European Climate Action priority to anticipate and minimise damage caused by climate change. Following my strong track record in science communication, I will disseminate my work widely to the scientific community, end-users and to the general public at the broadest level. The prestigious Marie Sk³odowska-Curie fellowship will allow me to develop the professional maturity to establish myself among the leaders of the European research community.;175866;175866;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN;IE;;;;1;0;0;1;0;0 207191;731086;AMICI;SIGNED;H2020-EU.1.4.2.1.;INFRAINNOV-02-2016;H2020;Accelerator and Magnet Infrastructure for Cooperation and Innovation;2017-01-01;2019-06-30;;Development and construction of accelerator based scientific Research Infrastructures are going through a deep paradigm change because of the need for large scale Technological Infrastructures at the forefront of technology to master the key accelerator and magnet science and technology needed for several fields. Indeed, because of the high technological level and of the increased size and time scale of projects, development and construction require more and more sophisticated R&D platforms on key accelerator and magnet technologies, large-scale facilities for their assembly, integration and verification, large concentrations of dedicated skilled personnel and long term relationships between laboratories and industry. In response to those challenges, a few large platforms specialized in interdisciplinary technologies and for applications of direct benefit to society are emerging. The emerging Technological Infrastructure is aiming at creating an efficient integrated ecosystem among laboratories focussed on R&D, with a long term vision for the technological needs of future RIs and industry, including SME, motivated by the innovative environment and the market created by the realisation of the technological needs of several RIs. With a timeline of 30 months, involving 10 Consortium partners, the AMICI proposal will ensure that A) a stronger and optimised integration model between the large existing technological infrastructures is developed and agreed upon, B) that this integrated ecosystem is attracting industries and fostering innovation based on accelerator and SC magnets cutting-edge developments, C) that strategy and roadmaps are clearly defined and understood to strongly position European industries and SMEs on the market of the construction of new Research Infrastructures worldwide, and D) that potential societal applications are identified and disseminated to the relevant partners of this ecosystem.;2279750;2279750;H2020-INFRAINNOV-2016-1;/CSA;COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES;FR;"THE HENRYK NIEWODNICZANSKI INSTITUTE OF NUCLEAR PHYSICS, POLISH ACADEMY OF SCIENCES;UPPSALA UNIVERSITET;SCIENCE AND TECHNOLOGY FACILITIES COUNCIL;UNITED KINGDOM RESEARCH AND INNOVATION;KARLSRUHER INSTITUT FUER TECHNOLOGIE;EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH;PAUL SCHERRER INSTITUT;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;STIFTUNG DEUTSCHES ELEKTRONEN-SYNCHROTRON DESY;ISTITUTO NAZIONALE DI FISICA NUCLEARE";"PL;SE;UK;DE;CH;FR;IT";;1;0;0;1;0;0 207004;722651;SEPOMO;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2016;H2020;Spins for Efficient Photovoltaic Devices based on Organic Molecules;2016-11-01;2020-10-31;;"Organic solar cells (OSCs) have the potential to become an environmental friendly, inexpensive, large area and flexible photovoltaics technology. Their main advantages are low process temperatures, the potential for very low cost due to abundant materials and scalable processing, and the possibility of producing flexible devices on plastic substrates. To improve their commercialization capacity, to compete with established power generation and to complement other renewable energy technologies, the performance of state-of-the-art OSCs needs to be further improved. Our goals within SEPOMO – Spins in Efficient Photovoltaic devices based on Organic Molecules – are to bring the performance of OSCs forward by taking advantage of the so far unexplored degree of freedom of photogenerated species in organic materials, their spin. This challenging idea provides a unified platform for the excellent research to promote the world-wide position of Europe in the field of organic photovoltaics and electronics, and to train strongly motivated early stage researchers (ESRs) for a career in science and technology oriented industry that is rapidly growing. Our scientific objectives are to develop several novel routes to enhance the efficiency of OSC by understanding and exploiting the electronic spin interactions. This will allow us to address crucial bottlenecks in state-of-the-art OSCs: we will increase the quantum efficiency by reducing the dominant recombination losses and by enhancing the light harvesting and exciton generation, e.g. by means of internal upconversion of excited states. Our ESRs will be trained within this interdisciplinary (physics, chemistry, engineering) and intersectoral (academia, R&D center, enterprise) consortium in highly relevant fundamental yet application-oriented research with the potential to commercialise the results. The hard and soft skills learned in our network are central for the ESRs to pursue their individual careers in academics or industry.";3826023,84;3826023,84;H2020-MSCA-ITN-2016;/MSCA-ITN-ETN;RIJKSUNIVERSITEIT GRONINGEN;NL;"MERCK CHEMICALS LTD;UNIVERSITE D'ANGERS;HELIATEK GMBH;AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS;UNIVERSITE DE MONS;TECHNISCHE UNIVERSITAET CHEMNITZ;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;FUNDACIO EURECAT;JULIUS-MAXIMILIANS-UNIVERSITAT WURZBURG;TECHNISCHE UNIVERSITAET DRESDEN";"UK;FR;DE;ES;BE";;1;0;0;1;0;0 207067;734801;MAGNAMED;SIGNED;H2020-EU.1.3.3.;MSCA-RISE-2016;H2020;Novel magnetic nanostructures for medical applications;2017-04-01;2021-03-31;;MAGNAMED designs, fabricates, and assesses novel magnetic nanostructures (MNS) with unique spin configurations for innovative diagnostics and therapy techniques. An early stage detection and an effective treatment are keystones to reduce cancer mortality. Current clinical procedures fail to detect small concentration of tumoral biomarkers. Magnetic nanoparticles (MNP), like beads, have attracted much attention for their capability to improve cancer detection limits and treatment technologies. However, there are several limitations to the use of MNP. As an emerging alternative, MNS are being explored. Unlike MNP, MNS (e.g. nanodisks) present a planar shape with novel properties for diagnosis: high magnetic moment and large size, which can significantly improve the sensor sensitivity, and for therapy: due to their planar shape, alternate magnetic fields provoke a magneto-mechanical action on the cell membrane that triggers cell death. The efficiency of MNS in these two medical applications has not been investigated yet for MNS at the nanometer scale. The challenge of this project is to produce MNS with nanometer dimensions suitable for medical applications. Several lithography techniques will be used to fabricate MNS in vortex and antiferromagnetic spin configurations covering a broad size range (40 to 4000 nm). After functionalization, MNS will be exploited in: (i) Diagnostics, using giant magnetoresistance (GMR) sensors for the detection of tumoral biomarkers (dermcidin and carcinoembryonic antigen), and (ii) Therapy, effectiveness of tumoral cell annihilation by the magneto-mechanical action of MNS will be evaluated in vitro assays of melanoma and colorectal cancer cells. MAGNAMED is a cross-sectoral and interdisciplinary project involving Physics, Chemistry and Medicine. Findings will have a medium-term impact on the European strategy for early stage detection of cancer and a long-term impact on the development of novel and groundbreaking therapeutics techniques.;846000;846000;H2020-MSCA-RISE-2016;/MSCA-RISE;UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA;ES;"VIENNA BIOCENTER CORE FACILITES GMBH;NANOVEX BIOTECHNOLOGIES SL;IMG PHARMA BIOTECH SOCIEDAD LIMITADA;UNIVERSIDAD COMPLUTENSE DE MADRID;INESC MICROSISTEMAS E NANOTECNOLGIAS-INSTITUTO DE ENGENHARIA DE SISTEMAS DE COMPUTADORES PARA OS MICROSISTEMAS E AS NANOTECNOLOGIAS;UNIVERSIDADE DO PORTO;ICETA INSTITUTO DE CIENCIAS, TECNOLOGIAS E AGROAMBIENTE DA UNIVERSIDADE DO PORTO";"AT;ES;PT";;1;0;0;1;0;0 207023;731957;MECHANO-CONTROL;SIGNED;H2020-EU.1.2.2.;FETPROACT-01-2016;H2020;Mechanical control of biological function;2017-01-01;2021-12-31;;Mechanical forces transmitted through specific molecular bonds drive biological function, and their understanding and control hold an uncharted potential in oncology, regenerative medicine and biomaterial design. However, this potential has not been realised, because it requires developing and integrating disparate technologies to measure and manipulate mechanical and adhesive properties from the nanometre to the metre scale. We propose to address this challenge by building an interdisciplinary research community with the aim of understanding and controlling cellular mechanics from the molecular to the organism scale. At the nanometric molecular level, we will develop cellular microenvironments enabled by peptidomimetics of cell-cell and cell-matrix ligands, with defined mechanical and adhesive properties that we will dynamically control in time and space trough photo-activation. The properties under force of the molecular bonds involved will be characterized using single-molecule atomic force microscopy and magnetic tweezers. At the cell-to-organ scale, we will combine controlled microenvironments and interfering strategies with the development of techniques to measure and control mechanical forces and adhesion in cells and tissues, and to evaluate their biological response. At the organism scale, we will establish how cellular mechanics can be controlled, by targeting specific adhesive interactions, to impair or abrogate breast tumour progression in a mouse model. At all stages and scales of the project, we will integrate experimental data with multi-scale computational modelling to establish the rules driving biological response to mechanics and adhesion. With this approach, we aim to develop specific therapeutic approaches beyond the current paradigm in breast cancer treatment. Beyond breast cancer, the general principles targeted by our technology will have high applicability in oncology, regenerative medicine and biomaterials.;7134928,75;7134928,75;FETPROACT-2016;/RIA;FUNDACIO INSTITUT DE BIOENGINYERIA DE CATALUNYA;ES;"MIND THE BYTE SL;NOVIOCELL BV;LEIBNIZ-INSTITUT FUER NEUE MATERIALIEN GEMEINNUETZIGE GMBH;UNIVERSITAIR MEDISCH CENTRUM UTRECHT;UNIVERSITAT POLITECNICA DE CATALUNYA;KING'S COLLEGE LONDON";"ES;NL;DE;UK";;1;0;0;1;0;0 206997;721465;ColOpt;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2016;H2020;Collective effects and optomechanics in ultra-cold matter;2017-01-01;2020-12-31;;"The network “Collective effects and optomechanics in ultra-cold matter” (ColOpt) will train early-stage researchers (ESR) in fundamental science and applications in the areas of cold atom and quantum physics, optical technologies and complexity science to promote European competiveness in emergent quantum technologies. It consists of nine academic nodes and three companies from six European countries, supported by two partners in Brazil and the USA, five further non-academic partners and one public-private partnership. Collective, nonlinear dynamics and spontaneous self-organization are abundant in nature, sciences and technology and of central importance. Building on this interdisciplinary relevance, a particular novelty of ColOpt is the integration of classical and quantum self-organization. The research program focuses on collective interactions of light with laser-cooled cold and quantum-degenerate matter. We will explore innovative control of matter through optomechanical effects, identify novel quantum phases, enhance knowledge of long-range coupled systems and advance the associated trapping, laser and optical technologies, establishing new concepts in quantum information and simulation. ColOpt combines cutting-edge science with training in complex instrumentation and methods to the highest level of technical expertise, both experimentally and theoretically, and fosters the development of transferable skills and critical judgement. Each ESR will be exposed to a broad spectrum of experimental, theoretical and industrial environments, to obtain core competence in one of them and the collaborative experience and skills to thrive in a truly international and intersectorial framework. ESRs will develop the capabilities to analyse and understand complex interactions, and will gain awareness of societal and entrepreneurial needs and opportunities. Taken together, this will enable them to excel in a variety of sectors of our diverse and rapidly changing society.";3893423,76;3893423,76;H2020-MSCA-ITN-2016;/MSCA-ITN-ETN;UNIVERSITY OF STRATHCLYDE;UK;"WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER;HOLOEYE PHOTONICS AG;M-SQUARED LASERS LIMITED;EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH;UNIVERSITA DEGLI STUDI DI MILANO;EBERHARD KARLS UNIVERSITAET TUEBINGEN;UNIVERSITY OF GLASGOW;UNIVERSITAET INNSBRUCK;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;TOPTICA PHOTONICS AG;UNIVERSITAT DES SAARLANDES";"DE;UK;CH;IT;AT;FR";;1;0;0;1;0;0 207038;734242;LAMBDA;SIGNED;H2020-EU.1.3.3.;MSCA-RISE-2016;H2020;Learning and Analysing Massive / Big complex Data;2017-03-01;2021-02-28;;"'LAMBDA aims at transferring game changing technologies to the European industry in critical areas of Machine learning. Based on recent algorithmic breakthroughs, we adapt sophisticated methods to targeted industries, with a twofold goal: First, to help turn cutting edge tools into innovative software products and processes, tailored to real-world issues. Second, based on the available data, to organise open data repositories and benchmarks, or to simulate data with the same statistical properties, when such data is confidential, following 'anonymisation'. LAMBDA focuses on two distinct application domains: 3D shape analysis and unstructured data mining. They share challenging features such as inherent complexity in modeling the data, high dimensionality which raises the issue of curse of dimensionality, and the need to address such datasets at a massive scale. Moreover, they correspond to the expertise of the participants. LAMBDA is characterised by a unique blend of theoretically rigorous and geometrically inclined methods, thus supporting a strong aspect of interdisciplinarity between Theory of Algorithms and Machine Learning. This shall be supported by advanced software development, ranging from public-domain prototype implementations to licensed software and integrated libraries, where the latter is based on the highly-optimised platform BIDMach, developed at UC Berkeley. LAMBDA strengthens existing links within Europe and across the Atlantic, while creating new synergies in the directions of two industrial domains, namely 3D shape search and insurance data. The two clusters are organised around representative companies in the respective domains. The Project is built so as to support knowledge transfer beyond its lifetime. Besides inter-sectoral collaborations, we exploit the international dimension by associating leading USA Universities, so as to bring state-of-the-art methods developed at the global level into the European framework.'";337500;337500;H2020-MSCA-RISE-2016;/MSCA-RISE;ETHNIKO KAI KAPODISTRIAKO PANEPISTIMIO ATHINON;EL;"3D INDUSTRIES LIMITED;GIE AXA";"UK;FR";;1;0;0;1;0;0 207075;737135;NANOARCHITECTRONICS;SIGNED;H2020-EU.1.2.1.;FETOPEN-02-2016;H2020;NANOARCHITECTRONICS;2017-01-01;2018-12-31;;"This FET-open Coordination and Support Action is called “Nanoarchitectronics” (NTX) to denote a new interdisciplinary research area at the crossroad of Electromagnetics and Nanoelectronics. NTX It is a new technology aimed at conceiving, designing and developing reconfigurable, adaptive and cognitive structures, sensorial surfaces and functional “skins” with unique physical properties, and engineering applications in the whole electromagnetic spectrum; through assembling building blocks at nanoscale in hierarchical architectures. The conception of this new area responds to the need of unifying concepts, methodologies and technologies in Communications, Environment Sensing Systems, Safety and Security, Bio-Sensing Systems and Imaging Nanosystems, within a wide frequency range. This FET project proposal gathers thirteen universities, research centers and high-tech industries, belonging to eight European countries. According to the FET work-program, the major objective of “Nanoarchitectronics” is to boost the future application-driven research through the establishment of an accepted language among physicists and engineers, a shared way of thinking, a common theoretical foundation and a common strategy for the future. Therefore, the project aims at laying the foundation for an ever-increasing synergy and progress of Nanoarchitectronics. To achieve these objectives, Nanoarchitectronics is structured in four main activities. The “Concept” activity is devoted to establish and define the concepts of Nanoarchitectronics and its boundaries with respect to other disciplines and to the activity carried out by other consortia. The “Strategy” activity identifies the policy dialogue and the strategic view of the consortium in terms of position, impact and vision. The “Virtual Networking” serves to internal web communication (private), and for dissemination (public). The “Dissemination and Exploitation” activity is carried out mainly by the industrial partners of the consortium";670000;670000;H2020-FETOPEN-2-2016;/CSA;UNIVERSITA DEGLI STUDI DI SIENA;IT;"ECOLE SUPERIEURE DE PHYSIQUE ET DECHIMIE INDUSTRIELLES DE LA VILLE DEPARIS;NEDERLANDSE ORGANISATIE VOOR TOEGEPAST NATUURWETENSCHAPPELIJK ONDERZOEK TNO;Teknologian tutkimuskeskus VTT Oy;FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.;FUNDACIO INSTITUT CATALA DE NANOCIENCIA I NANOTECNOLOGIA;VIRTUAL INSTITUTE FOR ARTIFICIAL ELECTROMAGNETIC MATERIALS AND METAMATERIALS - METAMORPHOSE VI AISBL;POLITECNICO DI TORINO;I.D.S. - INGEGNERIA DEI SISTEMI - S.P.A.;UNIVERSITA POLITECNICA DELLE MARCHE;THALES SA;KING'S COLLEGE LONDON";"FR;NL;FI;DE;ES;BE;IT;UK";;1;0;0;1;0;0 206927;707663;ANATOMY-FOUND;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Novel Imaging of the heart for new structural and metabolic diagnosis;2017-02-01;2019-01-31;;"Each year cardiovascular disease (CVD) causes over 4 million deaths in Europe. Predictions suggest that 80% of premature heart disease and stroke is preventable, but ~20% of CVDs are misdiagnosed, and in elderly patients up to 60% of CVDs remain undiagnosed. We need to develop new technologies and strategies for early and accurate diagnosis of the biggest killer in western society. Currently, diagnosis of CVD is based on assessment of macro-anatomy, whole heart function, and whole body metabolic markers. Early CVD processes begin in heart cells, before evolving to the ’macro’ pathology recognisable by traditional techniques. Clinicians desire a non-invasive technique that can provide high-resolution 3D micro-anatomy, and organ specific regional metabolic assessment. However the intricate micro-anatomy of the heart and its dynamic relationship with cardiac function is still fiercely debated. To elucidate the true micro-anatomy of the heart, and understand its correlation with both pump- and metabolic function in health and disease, I will investigate the following questions: 1)What is the true micro-anatomy of the heart, and how is it remodelled in disease? 2)What is the role of 3D micro-anatomy in 4D pump function? 3)Does micro-anatomical remodelling correlate with regional changes in metabolism? Using novel state-of-the-art non-invasive 3D and 4D ex-vivo and in-vivo imaging methodologies, I will answer these questions. We will finally understand the micro-anatomy of the heart in 3D, and its relationship with cardiac contraction and metabolism in disease. I hypothesise detecting and correlating novel morphological and metabolic changes upstream of the macro-anatomical and non-specific metabolic changes identifiable by traditional techniques, will offer the foundation for a step-wise change in diagnosis of CVD. Working with world-renowned researchers, I will develop interdisciplinary skills in functional cardiac imaging to support a productive career in academia.";200194,8;200194,8;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;AARHUS UNIVERSITET;DK;;;;1;0;0;1;0;0 206998;721536;Acoutect;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2016;H2020;A sound fundament for our future buildings;2017-01-01;2020-12-31;;"To ensure a healthy environment for people living and working in buildings, research and engineering in the area of building acoustics is essential. Developments in modern building concepts, such as sustainable low-energy consuming buildings, buildings with lightweight materials and open plan working environments, as well as the need to build in extremely noisy areas, require involvement of acoustic experts in order to successfully (re)design buildings without negatively impacting upon people’s health and well-being. Taking up current and future acoustic challenges requires innovative solutions based on a thorough understanding and mastering of modern methods and tools, as well as a holistic acoustic approach involving acoustic design, products and subjective evaluation. However, in the complex field of building acoustics, research activities typically are not holistic and have become slightly marginalised. As a consequence, there is a lack of building acoustics experts. To meet the future acoustic needs of the built environment, Acoutect is constructed around two objectives: 1) Establish a long-lasting European-wide training programme on building acoustics, 2) Launch an innovative research programme. With these objectives, Acoutect will equip ESRs with skills to ensure acoustic quality of modern and future building concepts, and with excellent perspectives for a career in industry or academia within the area of building acoustics. The training and supervision to reach these objectives is offered by the Acoutect consortium composed of 5 academic and 7 non-academic participants. This consortium comprises various disciplines and sectors within building acoustics and beyond, promoting intersectoral, interdisciplinary and innovative training and mobility of the researchers within the project.";3907082,88;3907082,88;H2020-MSCA-ITN-2016;/MSCA-ITN-ETN;TECHNISCHE UNIVERSITEIT EINDHOVEN;NL;"MATERIALISE NV;MATELYS - RESEARCH LAB;LEVEL ACOUSTICS BV;MOELVEN TOREBODA AB;AALTO KORKEAKOULUSAATIO SR;SIEMENS INDUSTRY SOFTWARE NV;THE UNIVERSITY OF LIVERPOOL;KATHOLIEKE UNIVERSITEIT LEUVEN;CHALMERS TEKNISKA HOEGSKOLA AB";"BE;FR;NL;SE;FI;UK";;1;0;0;1;0;0 204913;702584;PREKARN;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;The learning of prehistory of knapping stone;2016-07-01;2019-06-30;;"'The aim of this study is to identify the mechanics of cultural transmission among Pleistocene human groups and to provide new ideas for the investigation of occupational dynamics through lithic technological approach. Social learning informs us of the cognitive abilities to acquire knowledge transmitted between generations as adaptive strategies. In the archaeological record, the transmission of knowledge and the skills are identified through repetitive patterns, but most of them only remain in the best preserved archaeological material: the lithic tools that hominins made to survive. This project aims to ascertain how hominins learnt through the study of the size of the lithic tools (since novices knappers tend to prouce more small flakes that experienced knappers), and the management and know-how or “savoir-faire” of the knappers preserved into the archaeological collections. This will provide more information about the cognitive evolution of our ancestors. My goal is to study these mechanisms on the basis of two sections: The first part will consist in developing an experimental project to define morphotechnological characters that are crucial to learn the 'appropriate' size of the tools to made . The second part will be dedicated to track these morphotechnological characters in the archaeological record through an inter-disciplinary study, including technology, spatial and refitting analyses. The data obtained from these analyses will be processed jointly using a multivariate statistical analysis in order to identify technological patterns. These patterns differ between levels and sites, suggesting the possible existence of cultural identities or behavioural predispositions according to each human group. The integrated analysis of these different and complementary aspects guarantees the interdisciplinary and the innovative nature of the project, since this kind of research has never been conducted before at this level. '";195454,8;195454,8;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;UNIVERSITY COLLEGE LONDON;UK;;;;1;0;0;1;0;0 193970;642961;PACE;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2014-ETN;H2020;Perception and Action in Complex Environments;2015-04-01;2019-03-31;;The PACE research and training programme sits at the interface between basic science, technology and clinics, in order to unveil how humans control and adapt their movements in complex, naturalistic environments. Such a research agenda has major consequences for understanding how these movements are impacted by specific brain insults and how these impairments can be compensated for via new rehabilitation methods. Improving rehabilitation programmes for sensory and motor disabilities across the lifespan is a major societal challenge in western countries and many obstacles need to be overcome. To provide but one example, with regard to eye-hand coordination of upper limb movement remaining abilities are rarely assessed in stroke patients or sensory-disabled children and this impacts both prognostic estimation and rehabilitation. New technologies, such as robotics or virtual reality, provide an exciting change in perspective to transfer state-of-the-art knowledge from basic research on sensorimotor transformation into the clinical domain. To meet these societal challenges, it is crucial to train a new generation of early-stage researchers in a programme such as PACE where fundamental and applied/clinical research are effectively integrated via collaborative research, doctoral secondments and theoretical courses – in other words, one in which clinicians, neuroscientists, theoreticians and engineers can contribute around a well-defined problem: how humans acquire, lose and recover movement performance. With 8 academic, 1 clinical and 1 private beneficiaries, and 5 partner organizations (4 industrial, 1 in science communication), PACE structures a training and research programme that is both highly interdisciplinary and intersectoral. Our goal is to meet both fundamental and clinical well-identified challenges as well as preparing young scientists for future european research & development in the fields of human movement studies and rehabilitation medicine.;3911673,24;3911673,24;H2020-MSCA-ITN-2014;/MSCA-ITN-ETN;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FR;"MOTEK MEDICAL B.V.;STICHTING VU;NEDERLANDSE ORGANISATIE VOOR TOEGEPAST NATUURWETENSCHAPPELIJK ONDERZOEK TNO;UNIVERSITY OF DURHAM;BEN-GURION UNIVERSITY OF THE NEGEV;MEDICAL RESEARCH INFRASTRUCTURE DEVELOPMENT AND HEALTH SERVICES FUND BY THE SHEBA MEDICAL CENTER;FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA;UNIVERSITAT DE BARCELONA;UNIVERSITY COLLEGE LONDON";"NL;UK;IL;IT;ES";;1;0;0;1;0;0 193943;642720;BonePain;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2014-ETN;H2020;European Training Network on Bone Pain;2015-01-01;2018-12-31;;The aim is to create an innovative European PhD training network in bone pain. Millions in Europe and beyond suffer from bone pain, a debilitating complication of many musculoskeletal disorders such as arthritis and bone metastasis. However, being a truly multidisciplinary subject spanning neuroscience, bone biology, and even cancer research, it demands a multidisciplinary approach. Despite a huge negative impact on the quality of life of the patients and on society as a whole, no specific treatment is available. To address this societal challenge and the strong innovation potential, we want to form the first European platform to promote frontline research, innovation and education within bone pain. The network encompasses 5 academic and 2 industrial beneficiaries and 1 industrial partner all committed to creating an outstanding wide-ranging yet integrated training program for early stages researchers to elucidate the mechanisms of bone pain and develop new medicines. We will use in vivo models of arthritic pain, cancer-induced bone pain and fracture pain to investigate the pathophysiology and novel treatment strategies. In vivo electrophysiology will be used for studying the physiology and pharmacology of pain transmission and its modulation. Transgenic mouse models will be used to tease out the specific neuronal receptor subtypes involved. Sophisticated behaviour tests will evaluate response to novel treatments. We will create a biobank of human cancer-infiltrated bone to identify specific patterns of neuronal receptor expression and to validate therapeutic targets in humans. In an extensive training effort covering both specific research skills and transferable skills, the students will obtain an interdisciplinary, state-of-the-art and innovative training from the participants, several of which have experience from international networks. The students will benefit from secondments with industrial partners and with some of the foremost pain researchers in Europe;3558676,32;3558676,32;H2020-MSCA-ITN-2014;/MSCA-ITN-ETN;KOBENHAVNS UNIVERSITET;DK;"THE ROYAL VETERINARY COLLEGE;UNIVERSITAIR MEDISCH CENTRUM UTRECHT;KAROLINSKA INSTITUTET;GRUENENTHAL GMBH;NORDIC BIOSCIENCE A/S;UNIVERSITY COLLEGE LONDON;NORDIC BIOSCIENCE COMPOUND DEVELOPMENT A/S";"UK;NL;SE;DE;DK";;1;0;0;1;0;0 193816;641456;BINGO;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2014-ETN;H2020;Breeding Invertebrates for Next Generation BioControl (BINGO);2015-01-01;2018-12-31;;"BACKGROUND Secure and sustainable food production in terms of quantity and quality is a major challenge facing human societies. However, food security is continuously threatened by current and invasive pest species. EU regulations for the use of pesticides are getting stricter to ensure food safety and protect ecosystem health. Biocontrol of agricultural pests by using natural enemies has great potential to deal with these two demands. CHALLENGE Controlling novel exotic pests often involves importing non-native natural enemies. Such practices are undesirable as it poses risks to local biodiversity. Optimizing existing and native biocontrol agents can reduce the dependence on imported natural enemies. OBJECTIVE BINGO will advance current knowledge in biocontrol practice through the use of natural genetic variation and by simultaneously training 13 young researchers in an extensive suite of interdisciplinary skills. This will allow them to improve the efficiency of biological pest control through selective breeding of natural enemies in a broad range of agricultural systems and environmental conditions. HOW The research projects will address current bottlenecks in biocontrol, for rearing, monitoring and performance, that include a broad range of scientific disciplines and in which state-of-the-art population genomics will be applied. Industry has a pivotal role by providing the problems for research, training, and by translating the results to capacity building and increased competitiveness. RELEVANCE BINGO will deliver improved biocontrol agents, knowledge on the genetic organisation of traits related to agents’ performance, genetic markers for monitoring and risk assessment, and guidelines and protocols for genetic improvement of natural enemies. Crucially, BINGO will deliver eager ESRs that have the potential to thrive in professional environments in science, industry and public bodies to ensure that the biocontrol potential is met and implemented.";3288069;3288069;H2020-MSCA-ITN-2014;/MSCA-ITN-ETN;WAGENINGEN UNIVERSITY;NL;"Biologicke centrum AV CR, v. v. i.;FOOD AND AGRICULTURE ORGANIZATION OF THE UNITED NATIONS FAO;KOPPERT BV;UNIVERSITAET BREMEN;VETERINAERMEDIZINISCHE UNIVERSITAET WIEN;INSTITUTO VALENCIANO DE INVESTIGACIONES AGRARIAS;RIJKSUNIVERSITEIT GRONINGEN;INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE;CAB INTERNATIONAL";"CZ;IT;NL;DE;AT;ES;FR;UK";;1;0;0;1;0;0 193842;641639;BIOPOL;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2014-ETN;H2020;Biochemical and mechanochemical mechanisms in polarized cells;2015-01-01;2018-12-31;;BIOPOL is an interdisciplinary European training network at the interface of cell biology, physics and engineering. BIOPOL aims specifically at the understanding of fundamental mechanochemical principles guiding cellular behaviour and function and their relevance to human disease. A new supra-disciplinary research field is emerging bringing together the fields of molecular cell biology, physics and engineering aiming at an in depth understanding of fundamental cellular mechanochemical principles. BIOPOL combines exactly this required expertise in one joint training program for young researchers. BIOPOL has assembled a unique multidisciplinary consortium bringing together top scientists from the fields of molecular/developmental cell biology, membrane physics, engineering as well as specialists from the private sector. The scientific objectives focus on understanding of fundamental mechanisms of cellular mechanosensing in health and disease, the role of external forces in cell division and mechanochemical regulation of cell polarity including tissue formation. Finally, part of BIOPOL´s research program is the further development of cutting edge technologies like advanced atomic force microscopy, novel photonic tools like optical stretcher or innovative organ on a chip technology, exploiting physical cellular properties. BIOPOL´s collaborative cutting edge research program is integral part of its training program provided to early stage researcher and is further translated into seven state of the art experimental training stations representing the consortiums expertise. In addition, BIOPOL has developed a 3 years modular curriculum including workshops, summerschools, Business plan competitions and conferences with a specific agenda of transferable skill training elements highly relevant for scientific communication, translational research and in particular entrepreneurship.;3911897,16;3911897,16;H2020-MSCA-ITN-2014;/MSCA-ITN-ETN;THE UNIVERSITY OF SHEFFIELD;UK;"MIMETAS BV;THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;UNIVERSITA DEGLI STUDI DI PADOVA;CENTRO NACIONAL DE INVESTIGACIONESCARDIOVASCULARES CARLOS III (F.S.P.);INSTITUT CURIE;JPK INSTRUMENTS AG;UNIVERSITY COLLEGE LONDON;BIONCOTECH THERAPEUTICS SL;TECHNISCHE UNIVERSITAET DRESDEN";"NL;UK;IT;ES;FR;DE";;1;0;0;1;0;0 193985;643063;MICROWINE;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2014-ETN;H2020;MICROWINE - Microbial metagenomics and the modern wine industry;2015-01-01;2018-12-31;;A diverse, complex, and poorly characterised community of microorganisms lies at the heart of the wine – an industry worth over €220 billion globally. These microorganisms play key roles at all stages of the viniculture and vinification processes, from helping plants access nutrients from the soil, driving their health through protection against pathogens, to fermentation processes that transform the must into wine with its complex array of aromas and flavours. Given this importance, an improved understanding of the microbial community and its interplay will have significant effects on the industry. In recent years, 'Next Generation' DNA sequencing has revolutionised many areas of biology, including microbiology, through conferring the ability to characterise microbes on the deep community scale, through both ’shotgun’ and ’deep amplicon’ sequencing approaches. To exploit this power for the benefit of the wine industry, we propose MICROWINE, a 15 ESR Marie Curie Actions European Training Network. The network is constructed as a close collaboration between industry and academic partners, around the theme of the microbial community’s role in the wine production process. Through combining microbial metagenomic sequencing with powerful computation analyses, with metadata generated using techniques such as metabolomics and geochemistry, we will study the action of microbes from the plant protection and nutrition, through to wine fermentation process, using samples collected from both Europe and beyond. We will further train the ESRs across a wide range of relevant disciplines, and maximise information transfer through multiple host and academic-industry cosupervision and secondments. In this way, we anticipate contributing to the strength and scientific progress of the wine industry through training of a cohort of leading, interdisciplinary and tightly interconnected scientists at the forefront of modern microbiological, genomic, computational and related techniques.;3945597,12;3945597,12;H2020-MSCA-ITN-2014;/MSCA-ITN-ETN;AARHUS UNIVERSITET;DK;"INSTITUT NATIONAL DE RECHERCHE ENINFORMATIQUE ET AUTOMATIQUE;UNIVERSIDAD NACIONAL DE LA PLATA;STICHTING VU;UNIVERSIDAD DE ZARAGOZA;INSTITUTO SUPERIOR DE AGRONOMIA;KOBENHAVNS UNIVERSITET;UNIVERSIDADE CATOLICA PORTUGUESA;UNIVERSITE DE BORDEAUX;DANMARKS TEKNISKE UNIVERSITET;THE UNIVERSITY OF WARWICK;MINISTERIUM FUER UMWELT, LANDWIRTSCHAFT, ERNAEHRUNG, WEINBAU UND FORSTEN RHEINLAND- PFALZ;INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE";"FR;AR;NL;ES;PT;DK;UK;DE";;1;0;0;1;0;0 193981;643051;MiND;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2014-ETN;H2020;Mastering skills in the training Network for attention deficit hyperactivity and autism spectrum Disorders;2015-01-01;2018-12-31;;"Attention deficit/hyperactivity disorder (ADHD) and autism spectrum disorders (ASD) are frequent, chronic and highly heritable neurodevelopmental disorders. Despite their societal importance, progress in understanding disease biology has been slow and no curative treatment options are available. The pan-European training network MiND aims to educate a new generation of researchers in the field of neurodevelopmental disorders, through innovation-oriented research combined with highly interdisciplinary and intersectoral international training. Research and training in MiND span state-of-the-art topics in the fields of ADHD, ASD and their yet un-investigated overlap. We combine advanced (epi-)genetics approaches with bioinformatics and develop novel cell and animal models of increasing complexity to understand pathomechanisms. Integrated with research in large human DNA-neuroimaging-cognition data sets, we push forward the understanding of the biology leading from gene to cognition and disease. Our mechanistic work is embedded in a framework exploring alternative disease definitions for ADHD and ASD across the lifespan and working towards improved treatment: we use novel cognitive assessments, we probe the microbiome for dietary interventions reducing symptoms and evaluate mindfulness training as non-pharmacological treatment options, in addition to developing new compounds for pharmacological treatment optimization and individualization. The strategic collaboration of world-leading academic groups, research-intensive commercial enterprises and patient organisations will deliver 15 young, scientifically excellent researchers which are optimally prepared for private sector and academic careers. MiND can be expected to impact patients and society by improving our understanding of disease biology, by developing novel diagnostic and treatment strategies, and by raising awareness for the necessity of research of neurodevelopmental disorders from childhood to adulthood.";3913940,43;3913940,43;H2020-MSCA-ITN-2014;/MSCA-ITN-ETN;STICHTING KATHOLIEKE UNIVERSITEIT;NL;"UNIVERSITAETSKLINIKUM WUERZBURG - KLINIKUM DER BAYERISCHEN JULIUS-MAXIMILIANS-UNIVERSITAT;STICHTING KARAKTER;EUROFINS MEDIGENOMIX GMBH;BRAINGAZE SL;UNIVERSITAT DE BARCELONA;JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN;KAROLINSKA INSTITUTET;UNIVERSITY OF LEICESTER;FUNDACIO HOSPITAL UNIVERSITARI VALL D'HEBRON - INSTITUT DE RECERCA;FUNDACIO CENTRE DE REGULACIO GENOMICA;UNIVERSITETET I BERGEN;KING'S COLLEGE LONDON";"DE;NL;ES;SE;UK;NO";;1;0;0;1;0;0 193922;642536;CaFE;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2014-ETN;H2020;Development and experimental validation of computational models for cavitating flows, surface erosion damage and material loss;2015-01-01;2018-12-31;;Cavitation, described as the formation of vapour/gas bubbles of a flowing liquid in a region where the pressure of the liquid falls below its vapour pressure, often leads to vibration and damage of mechanical components, for example, bearings, fuel injectors, valves, propellers and rudders, impellers, pumps and hydro turbines. Cavitation erosion when experienced, normally leads to significant additional repair and maintenance costs or component replacement. Even if erosion problems can be avoided by design or operation, most often the performance of the systems is sub-optimal because countermeasures by design are needed to prevent cavitation problems. Despite the long-lasting problems associated with cavitation, computational models that could simulate cavitation and identify locations of erosion are still not thoroughly developed. The proposed interdisciplinary training and research programme aims to provide new experimental data and an open-source simulation tool for hydrodynamic cavitation and induced erosion. Insight into the detailed bubble collapse mechanism leading to surface erosion will be realised through DNS simulations, which are now feasible by the significant progress in fluid flow computational methods and parallel simulations. Information from such models will be implemented as sub-grid scale models of URANS and LES approaches, typically employed for cavitation simulation at engineering scales. Model validation will be performed against new advanced X-ray, laser diagnostics and high speed imaging measurements to be performed as part of this project. Application of the developed models to cases of industrial interest includes fuel injectors, marine propellers, hydro-turbines, pumps and mechanical heart valves. From this understanding the development of methodologies for design of cavitation-free or remedial measures and operation of devices suffering from cavitation erosion can then be established for the benefit of the relevant communities.;3939999,12;3939999,12;H2020-MSCA-ITN-2014;/MSCA-ITN-ETN;CITY UNIVERSITY OF LONDON;UK;"INSTITUT POLYTECHNIQUE DE GRENOBLE;TECHNISCHE UNIVERSITAET MUENCHEN;WAERTSILA NETHERLANDS B.V.;AVL LIST GMBH;Delphi Diesel Systems LTD;TECHNISCHE UNIVERSITEIT DELFT;CHALMERS TEKNISKA HOEGSKOLA AB";"FR;DE;NL;AT;UK;SE";;1;0;0;1;0;0 193940;642687;BIOGEL;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2014-ETN;H2020;Engineering responsive and biomimetic hydrogels for biomedical therapeutic and diagnostic applications;2015-01-01;2018-12-31;;"BIOGEL is set up to educate young scientists to develop innovative hydrogel chemistries and systems for biomedical applications. The first objective is to provide a platform for young researchers to undergo a well-rounded PhD education, particularly focussed on translational skills for a career focused in biomedical research and medical technology development. The second objective is to engineer functional and responsive hydrogels, which resemble specific properties of the extracellular matrix. The third objective is (i) to enhance the efficacy of medical devices by 2D biointegrative coatings that direct and orchestrate the interface to living cells and tissue and enable improved integration within the body, (ii) to advance therapeutic measures by 3D templates for tissue repair, and (iii) to enable new diagnostic tools by responsive diagnostic hydrogels. BIOGEL follows an international, interdisciplinary, and intersectoral approach organized in 9 and 8 interwoven work and training packages respectively. The training and research parts are focused on synthetic and biohybrid macromolecules to build clinically translatable hydrogels with specific, application directed bioactivities. In order to enable efficient biohybridisation and minimal invasive application, emphasis is set on in situ gelation of precursors that do not affect the viability of cells and living tissue and that can interlink bioactive subunits to stimulate tissue regeneration, and serve as a functional component in biomedical devices. Structural incorporation of such units must be flexible, dynamic, and responsive to stimuli. This is directed to enhance cell behavior and receptor interaction, tailor the mechanical properties, and enable spatial, temporal, and topographical control of functional components. Translational aspects focus on coatings of medical devices, diagnostic hydrogels, cartilage and bone repair, tissue engineering for cardiovascular implants, and nerve regeneration.";3522760,86;3522760,86;H2020-MSCA-ITN-2014;/MSCA-ITN-ETN;DWI LEIBNIZ-INSTITUT FUR INTERAKTIVE MATERIALIEN EV;DE;"NovioSense BV;TECHNICAL PROTEINS NANOBIOTECHNOLOGY SL;AIT AUSTRIAN INSTITUTE OF TECHNOLOGY GMBH;ETHNIKO KENTRO EREVNAS KAI TECHNOLOGIKIS ANAPTYXIS;UNIVERSIDAD DE VALLADOLID;STICHTING KATHOLIEKE UNIVERSITEIT;LIFETEC GROUP BV;PEPSCAN THERAPEUTICS BV";"NL;ES;AT;EL";;1;0;0;1;0;0 193971;642963;BigStorage;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2014-ETN;H2020;BigStorage: Storage-based Convergence between HPC and Cloud to handle Big Data;2015-01-01;2018-12-31;;"'The consortium of this European Training Network (ETN) 'BigStorage: Storage-based Convergence between HPC and Cloud to handle Big Data” will train future data scientists in order to enable them and us to apply holistic and interdisciplinary approaches for taking advantage of a data-overwhelmed world, which requires HPC and Cloud infrastructures with a redefinition of storage architectures underpinning them - focusing on meeting highly ambitious performance and energy usage objectives. There has been an explosion of digital data, which is changing our knowledge about the world. This huge data collection, which cannot be managed by current data management systems, is known as Big Data. Techniques to address it are gradually combining with what has been traditionally known as High Performance Computing. Therefore, this ETN will focus on the convergence of Big Data, HPC, and Cloud data storage, ist management and analysis. To gain value from Big Data it must be addressed from many different angles: (i) applications, which can exploit this data, (ii) middleware, operating in the cloud and HPC environments, and (iii) infrastructure, which provides the Storage, and Computing capable of handling it. Big Data can only be effectively exploited if techniques and algorithms are available, which help to understand its content, so that it can be processed by decision-making models. This is the main goal of Data Science. We claim that this ETN project will be the ideal means to educate new researchers on the different facets of Data Science (across storage hardware and software architectures, large-scale distributed systems, data management services, data analysis, machine learning, decision making). Such a multifaceted expertise is mandatory to enable researchers to propose appropriate answers to applications requirements, while leveraging advanced data storage solutions unifying cloud and HPC storage facilities.'";3803407,92;3803407,92;H2020-MSCA-ITN-2014;/MSCA-ITN-ETN;UNIVERSIDAD POLITECNICA DE MADRID;ES;"INSTITUT NATIONAL DE RECHERCHE ENINFORMATIQUE ET AUTOMATIQUE;FUJITSU TECHNOLOGY SOLUTIONS GMBH;JOHANNES GUTENBERG-UNIVERSITAT MAINZ;SEAGATE SYSTEMS UK LIMITED;COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES;FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS;DEUTSCHES KLIMARECHENZENTRUM GMBH;BARCELONA SUPERCOMPUTING CENTER - CENTRO NACIONAL DE SUPERCOMPUTACION;CA TECHNOLOGIES DEVELOPMENT SPAIN SA";"FR;DE;UK;EL;ES";;1;0;0;1;0;0 193432;636876;REDMUD;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2014-ETN;H2020;European Training Network for Zero-waste Valorisation of Bauxite Residue (Red Mud);2014-12-01;2019-10-31;;To tackle its (critical) raw material dependency, Europe needs comprehensive strategies based on sustainable primary mining, substitution and recycling. Freshly produced flows and stocks of landfilled industrial residues such as mine tailings, non-ferrous slag and bauxite residue (BR) can provide major amounts of critical metals and, concurrently, minerals for low-carbon building materials. The European Training Network for Zero-Waste Valorisation of Bauxite Residue (REDMUD) therefore targets the vast streams of new and stockpiled BR in the EU-28. BR contains several critical metals, is associated with a substantial management cost, whereas spills have led to major environmental incidents, including the Ajka disaster in Hungary. To date, zero-waste valorisation of BR is not occurring yet. The creation of a zero-waste BR valorisation industry in Europe urgently requires skilled scientists and engineers, who can tackle the barriers to develop fully closed-loop environmentally-friendly recovery flow sheets. REDMUD trains 15 researchers in the S/T of bauxite residue valorisation, with emphasis on the recovery of Fe, Al, Ti and rare earths (incl. Sc) while valorising the residuals into building materials. An intersectoral and interdisciplinary collaboration of EU-leading institutes and scientists has been established, which covers the full value chain, from BR to recovered metals and new building materials. Research challenges include the development of efficient extraction of Fe, Al, Ti and rare earths (incl. Sc) from distinct (NORM classified) BRs and the preparation of new building materials with higher than usual Fe content. By training the researchers in pyro-, hydro- and ionometallurgy, electrolysis, rare-earth extraction and separation technology, inorganic polymer and cement chemistry, Life Cycle Assessment (LCA), NORM aspects and characterisation, they become the much needed scientists and engineers for the growing European critical raw materials industry.;3720893,4;3720893,4;H2020-MSCA-ITN-2014;/MSCA-ITN-ETN;KATHOLIEKE UNIVERSITEIT LEUVEN;BE;"TARTU ULIKOOL;HELSINGIN YLIOPISTO;KUNGLIGA TEKNISKA HOEGSKOLAN;RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN;NATIONAL TECHNICAL UNIVERSITY OF ATHENS - NTUA;TITAN CEMENT COMPANY AE;MYTILINEOS ANONIMI ETAIRIA - OMILOS EPICHEIRISEON;MEAB CHEMIE TECHNIK GMBH;ALOUMINION TIS ELLADOS VIOMICHANIKI KAI EMPORIKI ANONYMOS ETAIREIA VEAE";"EE;FI;SE;DE;EL";;1;0;0;1;0;0 193338;635568;LAkHsMI;SIGNED;H2020-EU.3.2.;BG-09-2014;H2020;Sensors for LArge scale HydrodynaMic Imaging of ocean floor;2015-04-01;2019-09-30;;LAkHsMI will develop a new bio-inspired technology to make continuous and cost-effective measurements of the near-field, large-scale hydrodynamic situation, for environmental monitoring in cabled ocean observatories, marine renewable energy and port/harbor security. We will design, manufacture, and field test prototype smart sensor cables that measure differential pressure and temperature on the ocean floor and enable high resolution imaging of the surrounding volume in space and time, is simple, inexpensive and has very low power consumption The cables can be connecting with existing cabled ocean observatories. The technology is inspired by the biophysics of fish hydrodynamic sensing. The technology is scalable from meters to possibly hundreds of kilometers and allows a high sampling frequency. LAkHsMI will also develop innovative methods for hydrodynamic imaging. It produces several continuous on-line information products for interdisciplinary oceanography and seismic geophysics but also for other applications including tracking fish and fish schools or (sub)surface traffic in harbours. Software interfaces developed in the course of the project will be integrated with existing observatory systems (such as EUROGOOS). LAkHsMI will design and implement the sensor cables on small large scales. Tests will be conducted in a tank, a pool, an in ocean observatory.;3040221,25;3040221,25;H2020-BG-2014-2;/RIA;TALLINNA TEHNIKAULIKOOL;EE;"OU ELIKO TEHNOLOOGIA ARENDUSKESKUS;AQUATERA LIMITED;HERIOT-WATT UNIVERSITY;RIJKSUNIVERSITEIT GRONINGEN;HYDRO BOND ENGINEERING LIMITED";"EE;UK;NL";;1;0;0;1;0;0 211416;752162;DarkGAMBIT;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Global searches for dark matter and new physics with GAMBIT using effective field theory;2018-02-01;2020-01-31;;'The nature of dark matter (DM) is arguably the biggest mystery in fundamental physics. Many experimental efforts are underway which aim to detect this elusive matter and measure its properties, using a wide variety of techniques, however to make full use of this data a combined statistical analysis must be performed which makes use of the data from all these experiments simultaneously, and compares this data to the predictions of many different theories while including all uncertainties, correlations and theoretical nuances self-consistently. Analyses of this kind are known as 'global fits'. I propose to use a newly developed, open-source global-fitting tool called GAMBIT to perform the largest and most robust combined statistical analysis of DM data to date. To do this I will extend the capabilities of GAMBIT to allow it to work with a class of models known as 'effective theories' which efficiently parameterise the degrees of freedom relevant to experiments at a particular energy scale, so that a global fit can be performed in a fully model-independent way. This will require several connected layers of effective theory to be utilised, to account for the different energy scales involved in the diverse set of DM experiments currently underway. The project is highly interdisciplinary and makes use of recent theoretical developments and experimental results in high energy physics, particle astrophysics, astronomy, nuclear physics, and computational statistics. The proposal will generate a transfer of knowledge to the host institution while developing the candidate's theoretical expertise in new directions, particularly particle astrophysics. The results of the project will be of wide use to the dark matter community, both in terms of direct analysis results and via the development of open-source computational tools for use in future analyses, and will provide robust guidance to experimentalists as to which dark matter candidates are the most promising.';183454,8;183454,8;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE;UK;;;;1;0;0;1;0;0 193323;635201;LANDMARK;SIGNED;H2020-EU.3.2.;SFS-04-2014;H2020;LAND Management: Assessment, Research, Knowledge base;2015-05-01;2019-10-31;;"LANDMARK is a pan-European multi-actor consortium of leading academic and applied research institutes, chambers of agriculture and policy makers that will develop a coherent framework for soil management aimed at sustainable food production across Europe. The LANDMARK proposal builds on the concept that soils are a finite resource that provides a range of ecosystem services known as “soil functions”. Functions relating to agriculture include: primary productivity, water regulation & purification, carbon-sequestration & regulation, habitat for biodiversity and nutrient provision & cycling. Trade-offs between these functions may occur: for example, management aimed at maximising primary production may inadvertently affect the ‘water purification’ or ‘habitat’ functions. This has led to conflicting management recommendations and policy initiatives. There is now an urgent need to develop a coherent scientific and practical framework for the sustainable management of soils. LANDMARK will uniquely respond to the breadth of this challenge by delivering (through multi-actor development): 1. LOCAL SCALE: A toolkit for farmers with cost-effective, practical measures for sustainable (and context specific) soil management. 2. REGIONAL SCALE - A blueprint for a soil monitoring scheme, using harmonised indicators: this will facilitate the assessment of soil functions for different soil types and land-uses for all major EU climatic zones. 3. EU SCALE – An assessment of EU policy instruments for incentivising sustainable land management. There have been many individual research initiatives that either address the management & assessment of individual soil functions, or address multiple soil functions, but only at local scales. LANDMARK will build on these existing R&D initiatives: the consortium partners bring together a wide range of significant national and EU datasets, with the ambition of developing an interdisciplinary scientific framework for sustainable soil management.";5307551,25;4999663;H2020-SFS-2014-2;/RIA;WAGENINGEN UNIVERSITY;NL;"UNIVERSITATEA DE STIINTE AGRICOLE SI MEDICINA VETERINARA CLUJ NAPOCA;UNIVERSITA DEGLI STUDI DI PARMA;UNIVERSITEIT ANTWERPEN;SZENT ISTVAN UNIVERSITY;MEDNARODNA PODIPLOMSKA SOLA JOZEFA STEFANA;KOBENHAVNS UNIVERSITET;OSTERREICHISCHE AGENTUR FUR GESUNDHEIT UND ERNAHRUNGSSICHERHEIT GMBH;INSTITUTE OF SOIL SCIENCE CHINESE ACADEMY OF SCIENCES;SVERIGES LANTBRUKSUNIVERSITET;TEAGASC - AGRICULTURE AND FOOD DEVELOPMENT AUTHORITY;RIJKSINSTITUUT VOOR VOLKSGEZONDHEID EN MILIEU;LANDWIRTSCHAFTSKAMMER NIEDERSACHSEN;EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH;ASSEMBLEE PERMANENTE DES CHAMBRES D'AGRICULTURE;THE CIRCA GROUP EUROPE LIMITED;INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE;UNIVERSITY OF ULSTER;STICHTING WAGENINGEN RESEARCH;UNIVERSIDAD DE SEVILLA;UNIVERSIDADE DE SAO PAULO;JRC -JOINT RESEARCH CENTRE- EUROPEAN COMMISSION";"RO;IT;BE;HU;SI;DK;AT;CN;SE;IE;NL;DE;CH;FR;UK;ES;BR";;1;0;0;1;0;0 206299;703201;TRANSNATIONALaw;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-GF;H2020;Transnationalism and Unofficial Law: The Case of Kurds in Turkey and Germany;2017-01-01;2019-12-31;;The use of multiple legal practices based on diverse normative perceptions increasingly challenges the monopoly of state law. In Europe, this issue has become especially visible in the ongoing discussions about sharia courts. However, there is only limited research about the practical implications of non-state legal orders, particularly in relation to their effects on women’s rights and gender relations. The proposed research aims to start filling this gap by investigating the non-state justice systems operating in Berlin, the city with the largest Kurdish population in Europe, and Diyarbakir, the largest Kurdish-dominated city in Turkey. An evidence-based foundation is needed if the legal order and conceptualizations of citizenship are to be fit for increasingly diverse societies. In-depth interviews and participant observation will be used to investigate when, why and how Kurdish communities in Diyarbak?r and Berlin choose alternative dispute resolution over the official court procedures provided by the state. There will be a special focus on family cases to examine how gender norms and relations are affected by the use of non-state judicial processes. A historical perspective on the Diyarbakir-based ‘unofficial’ legal order will explore the non-European and non-religious roots of unofficial dispute resolution practices used within Europe. The transnational perspective will also enable an investigation of the mutual influences across non-state and state legal orders in Europe and the Middle East. This interdisciplinary project aims to fill a significant gap in the relevant socio-legal, gender, migration, political academic studies and policy debates within the European Research Area. This proposed project will be hosted by SOAS University of London (Beneficiary) in partnership with Syracuse University (SU) (Partner Organization in TC), New York. There will be additional mobility to the the Max Planck Institute (MPI) for Social Anthropology.;251857,8;251857,8;H2020-MSCA-IF-2015;/MSCA-IF-GF;SCHOOL OF ORIENTAL AND AFRICAN STUDIES ROYAL CHARTER;UK;;;;1;0;0;1;0;0 206352;731954;PIXAPP;SIGNED;H2020-EU.2.1.1.;ICT-29-2016;H2020;Photonic Integrated Circuits Assembly and Packaging Pilot Line;2017-01-01;2020-12-31;;"PIXAPP will establish the world’s first open access Photonic Integrated Circuit (PIC) assembly & packaging Pilot Line. It combines a highly-interdisciplinary team of Europe’s leading industrial & research organisations. PIXAPP provides Europe’s SMEs with a unique one-stop-shop, enabling them to exploit the breakthrough advantages of PIC technologies. PIXAPP bridges the ‘valley of death’, providing SMEs with an easy access route to take R&D results from lab to market, giving them a competitive advantage over global competition. Target markets include communications, healthcare & security, which are of great socio-economic importance to Europe. PIXAPP’s manufacturing capabilities can support over 120 users per year, across all stages of manufacturing, from prototyping to medium scale manufacture. PIXAPP bridges missing gaps in the value chain, from assembly & packaging, through to equipment optimisation, test and application demonstration. To achieve these ambitious objectives, PIXAPP will; 1) Combine a group of Europe’s leading industrial & research organisations in an advanced PIC assembly & packaging Pilot Line facility.2) Develop an innovative Pilot Line operational model that coordinates activities between consortium partners & supports easy user access through a single entry point. 3) Establish packaging standards that provide cost-efficient assembly & packaging solutions, enabling transfer to full-scale industrial manufacture. 4) Create the highly-skilled workforce required to manage & operate these industrial manufacturing facilities.5) Develop a business plan to ensure Pilot Line sustainability & a route to industrial manufacturing. PIXAPP will deliver significant impacts to a wide stakeholder group, highlighting how industrial & research sectors can collaborate to address emerging socio-economic challenges.";15707171,43;13407812,76;H2020-ICT-2016-1;/IA;UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK;IE;"EUROPEAN PHOTONICS INDUSTRY CONSORTIUM;Teknologian tutkimuskeskus VTT Oy;FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.;COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES;INTERUNIVERSITAIR MICRO-ELECTRONICA CENTRUM;XIO PHOTONICS BV;LIONIX INTERNATIONAL BV;CORDON ELECTRONICS ITALIA SRL;KARLSRUHER INSTITUT FUER TECHNOLOGIE;Randox Laboratories Ltd;III-V LAB;ARGOTECH AS;TECHNOBIS IPPS BV;Linkra S.R.L.;TECHNISCHE UNIVERSITEIT EINDHOVEN;FICONTEC SERVICE GMBH;MICROFLUIDIC CHIPSHOP GMBH;EBLANA PHOTONICS LIMITED;PHOENIX BV";"FR;FI;DE;BE;NL;IT;UK;CZ;IE";;1;0;0;1;0;0 206509;732032;BrainCom;SIGNED;H2020-EU.1.2.2.;FETPROACT-01-2016;H2020;High-density cortical implants for cognitive neuroscience and rehabilitation of speech using brain-computer interfaces.;2016-12-01;2021-11-30;;The goal of BrainCom is to develop a new generation of neuroprosthetic devices for large-scale and high density recording and stimulation of the human cortex, suitable to explore and repair high-level cognitive functions. Since one of the most invalidating neurospychological conditions is arguably the impossibility to communicate with others, BrainCom primarily focuses on the restoration of speech and communication in aphasic patients suffering from upper spinal cord, brainstem or brain damage. To target broadly distributed neural systems as the language network, BrainCom proposes to use novel electronic technologies based on nanomaterials to design ultra-flexible cortical and intracortical implants adapted to large-scale high-density recording and stimulation. The main challenge of the project is to achieve flexible contact of broad cortical areas for stimulation and neural activity decoding with unprecedented spatial and temporal resolution. Critically, the development of such novel neuroprosthetic devices will permit significant advances to the basic understanding of the dynamics and neural information processing in cortical speech networks and the development of speech rehabilitation solutions using innovative brain-computer interfaces. Beyond this application, BrainCom innovations will enable the study and repair of other high-level cognitive functions such as learning and memory as well as other clinical applications such as epilepsy monitoring using closed-loop paradigms. BrainCom will be carried out by a consortium assembled to foster the emergence of a new community in Europe acting towards the development of neural speech prostheses. Thanks to its high interdisciplinarity involving technology, engineering, biology, clinical sciences, and ethics, BrainCom will contribute advances to all levels of the value chain: from technology and engineering to basic and language neuroscience, and from preclinical research in animals to clinical studies in humans.;8648827,89;8359862,5;FETPROACT-2016;/RIA;FUNDACIO INSTITUT CATALA DE NANOCIENCIA I NANOTECNOLOGIA;ES;"MULTI CHANNEL SYSTEMS MCS GMBH;LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN;THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;WAVESTONE LUXEMBOURG SA;UNIVERSITE DE GENEVE;AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS;UNIVERSITE GRENOBLE ALPES;ASSOCIATION POUR LA RECHERCHE ET LE DEVELOPPEMENT DES METHODES ET PROCESSUS INDUSTRIELS;CENTRE HOSPITALIER UNIVERSITAIRE DE GRENOBLE;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD";"DE;UK;LU;CH;ES;FR";;1;0;0;1;0;0 206487;715467;TBTF;SIGNED;H2020-EU.1.1.;ERC-2016-STG;H2020;Addressing Too Big to Fail: Resolution, Organizational Structure, and Funding of Global Banks;2016-12-01;2021-11-30;;"One of the main unresolved challenges of the recent financial crisis is how society should deal with global banks that are “too big to fail.” The collapse of Lehman Brothers vividly demonstrated the costs of the failure of such an institution, with sweeping repercussions for the financial system and the broader economy. Yet, implicit public guarantees that would prevent such failures are equally costly, creating moral hazard in the form of increased risk taking and incentives for financial institutions to become larger and more complex. The research in this proposal will address this dilemma. From a methodological perspective, my research will advance the state of the art in financial intermediation theory by explicitly modeling the failure and resolution of global banks, emphasizing crucial elements that are absent from leading theories: the design of mechanisms that allow for an orderly resolution of struggling global financial institutions, the incentives of national authorities in the regulation and resolution of global banks, the role of the corporate and organizational structure of global banks, as well as their optimal size and scope. The proposed approach is interdisciplinary; it will generate novel insights by drawing on different subfields within economics (corporate finance theory, organizational economics) and aspects of bankruptcy law. Moreover, the research will take a holistic view that explicitly recognizes the two-way feedback between the rules that govern bank resolution and decisions on funding, investment, and size taken by banks prior to a potential resolution. Overall, the findings from this research will be directly relevant for regulators and policymakers. For example, they will inform currently debated legislation regarding the regulation and resolution of global banks, such as the Single Resolution Mechanism in the EU.";1489518;1489518;ERC-2016-STG;/ERC-STG;LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE;UK;;;;1;0;0;1;0;0 204722;681466;TRANS-ID;SIGNED;H2020-EU.1.1.;ERC-CoG-2015;H2020;TIME FOR A CHANGE: An out-of-the-box approach to unravel transitions in depression;2016-08-01;2021-07-31;;"Major Depression (MD) is often chronic and characterized by frequent recurrences of symptoms and burden. The need to better understand how and when relevant transitions in symptoms occur is urgent. A seemingly unsolvable scientific problem is the enormous etiological complexity of mental disorders such as MD, involving continuously ongoing gene-environment interactions that act in highly person-specific ways. This hampers accurate assessment of personalized risk. I will use an out-of-the-box and interdisciplinary approach to tackle this problem. MD is not the only phenomenon that is influenced by many factors, is unpredictable and makes sudden transitions. This is also the case for other so-called complex dynamical systems such as climate or water quality of lakes. For the latter systems generic early warning signals (EWS) have been found that indicate the approach of a transition. I hypothesize that transitions in mood can be anticipated using the same generic EWS as reported for other complex dynamical systems. Finding direct evidence for this hypothesis requires a completely novel approach in the field of psychiatry, which would involve (i) a design that captures data of the complete dynamic process within a single individual in order to detect the timing of EWS and sudden transitions in symptoms, prospectively and intra-individually, and (ii) frequent replications of these individual experiments. With help of recent technology and my acquired expertise I will use precisely this novel approach to search for personalized EWS that anticipate critical transitions in depression. This is the aim of my project. Evidence that transitions in mood behave according to principles of complex dynamical systems would change the field majorly. First, it would lead to a new understanding of mental disorders and the way we study them. Second, it would yield a sophisticated novel way of obtaining personalized and clinically relevant information on risk for transitions.";1994076;1994076;ERC-2015-CoG;/ERC-COG;ACADEMISCH ZIEKENHUIS GRONINGEN;NL;;;;1;0;0;1;0;0 205930;731868;VIRUSCAN;SIGNED;H2020-EU.1.2.2.;FETPROACT-01-2016;H2020;Optomechanics for Virology;2016-11-01;2021-10-31;;"Viral infections diagnosis demands novel, cheaper and rapid technologies to overcome present constraints. Current gold standard for diagnosis of viral infections is based on pathogen-targeted nucleic acid identification; thus, it cannot discern infectious stages from latent ones and it demands time consuming adjustments when mutations occur or new emerging viruses are to be included in the diagnostic protocols. Lately, optomechanics has served to fundamental advancements in physics, from gravitational wave detection to the study of mechanical quantum ground states but it has not yet delivered its full applicability potential. VIRUSCAN aims to apply frontier advancements in optomechanics to the biosensing and diagnostic fields and to create a new interdisciplinary research community with the goal to advance optomechanics, nanoelectromechanics, native mass spectrometry and biophysics towards clinical applications. VIRUSCAN will provide a novel technology capable to identify viral particles and asses their infective potential through the characterization of two physical parameters: mass and stiffness. Stiffness of viral particles has been recently known to act as a regulator of their infectivity at different stages of the virus life cycle. In parallel, advancements in nanoelectromechanical systems have recently demonstrated that stiffness and mass information from nanoscale adsorbates can be disentangled. Targeting intrinsic physical properties of viral particles will allow developing an open platform that will tackle any virus and their mutations. VIRUSCAN will have impact at all levels by: providing a personalized treatment to the patients, reducing the use of not effective antibiotics, increasing safety in blood transfusions, allowing a quick and trustworthy response to emergency situations (e.g. recent EBOLA in West Africa and the ZIKA in Brazil), reducing the spread of viral infections, reducing costs per analysis and screening of a wide range of pathogens.";7148586,25;7148586,25;FETPROACT-2016;/RIA;AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS;ES;"UNIVERSITE PARIS DIDEROT - PARIS 7;NEDERLANDSE ORGANISATIE VOOR TOEGEPAST NATUURWETENSCHAPPELIJK ONDERZOEK TNO;COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES;SERVICIO MADRILENO DE SALUD;FASMATECH EPISTIMONIKI KAI TECHNOLOGIKI ANONYMI ETAIREIA;RIJKSUNIVERSITEIT GRONINGEN;HEINRICH-PETTE INSTITUT LEIBNIZ INSTITUT FUER EXPERIMENTELLE VIROLOGIE";"FR;NL;ES;EL;DE";;1;0;0;1;0;0 204947;707848;HOUSREG;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Social Art as a Tool for Empowerment: Housing Deprivation and Citizen Initiatives for Change;2016-08-01;2018-07-31;;"Over the past decade, worsening affordability,homelessness, social and housing polarisation and new forms of housing deprivation have been an increasing concern for public policy in Europe. Symptom of this problem is a set of art projects focused on housing issues. These social art projects have also served to highlight and fill the gap left by inexistent social structures, which should ideally provide wellbeing for all. The art projects about housing paired with other initiatives coming from civil society (as non-governmental organizations with social and humanitarian foundation, social entrepreneurship, and volunteer based social initiatives) have a potential to engage citizens creatively and initiate positive social change by increasing wellbeing and community feeling. Addressing this need, the overarching objective of this project is to deliver a new methodology that will address Social Art and Housing. This methodology will allow the Fellow to outline the best practice for how art can be used in housing planning, for enhancing the quality of life in decaying neighborhoods, in urban regenerations, and homelessness problems. To achieve this objective the project will bring together a talented researcher with a background in art and urban theory to work with an internationally recognized research group with expertise in actor network theory, social art and field research design in order to deliver a novel interdisciplinary methodology developed through empirical research and validated through case studies in the UK and Serbia. The following research objectives will deliver the key components of the new social art and housing methodology: Objective 1: to map actors in the field of social art and housing networks Objective 2: to develop models of best practices of social art and housing networks Objective 3: to refine the models through comparison of best practices in Serbia and UK The research will be divided in six stages organized in six work packages.";195454,8;195454,8;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;LONDON SOUTH BANK UNIVERSITY LBG;UK;;;;1;0;0;1;0;0 206291;701664;RADoTE;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Remote-Activated Delivery of Therapeutic Exosomes (RADoTE) via an Injectable PEG Hydrogel Carrier;2016-11-01;2018-10-31;;As a Marie Sk³odowska-Curie Fellow, I will develop and demonstrate remote-activated delivery of biological therapeutics loaded into an injectable hydrogel, where delivery is triggered by applying near-infrared (NIR) light that safely and non-invasively penetrates deep into living tissues. The hydrogel carrier will be designed to deliver and stabilize cell-derived exosomes and microvesicles, together referred to as extracellular vesicles (EVs), which have recently gained attention for their ability to effectively deliver biological information and cargo directly to target cells. Developing sophisticated delivery systems for EVs will streamline their translation to clinical application, enabling the huge potential for this novel biological therapeutic to be fully realized. This system will be advantageous in simultaneously providing localized delivery, enhanced EV stability, and crucially, externally triggered release. This project will provide the first demonstration of localized and controlled delivery of EVs, with the added novelty of an externally NIR-triggered delivery system. By combining my expertise in designer hydrogel chemistry, the supervision of Prof. Molly Stevens at Imperial College London (ICL) who runs a world-class interdisciplinary biomaterials-focused group, and a secondment with The Technology Partnership (TTP) specializing in technology translation, this project is ideally situated to deliver the highest quality results.;183454,8;183454,8;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE;UK;;;;1;0;0;1;0;0 206311;707962;CyBioSys;CLOSED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;An affordable Cyber Biological System combining swarming biosensors and robotics;2016-09-01;2018-08-31;;Bio-inspiration is a main driving force for the development of innovative and adapted artificial systems. Going one step further, the fundamental goal of this proposal is to design a cyber biological system (CBS) that interfaces a swarm of animals with a distributed artificial system. Our objective is to demonstrate that such CBS can benefit from advantages of both artificial and natural systems and outperform their constituents. Here, the goal of the CBS is to explore the environment searching for resources and to exploit them as soon as discovered. For this purpose, we integrate a model organism of biological societies, the ants, with an artificial system based on mobile robots, the Thymio. More specifically, the CBS will be composed by an ant nest coupled to static sensors that communicate with mobile robots. The ants will explore the environment and evaluate potential food sources. Once a source is discovered, static sensors placed at the nest exits will detect the increasing flow of ants recruited toward the resource and transmit this information to the mobile robots. Once alerted, the mobile robots will navigate in the environment and follow the ants until the food source to convey it to the nest. Thus, the CBS will benefit from the efficient exploration pattern of the ants to discover and evaluate potential resources and the ability of the robots to rapidly convey these resources to the nest. This synergy will save the energy that should be consumed by the robots for constantly exploring the environment and quicken the collect of the food, making the ants more rapidly available for further exploration. This project is the first to consider an insect swarm as a biosensor and to embed in a robot the ability to extract data from such swarm. In addition, this interdisciplinary project at the crossroads of biology and robotics ensures the development of skills and transfer of knowledge for the ER as well as the host organisation.;175419,6;175419,6;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE;CH;;;;1;0;0;1;0;0 204743;682473;BCM-UPS;SIGNED;H2020-EU.1.1.;ERC-CoG-2015;H2020;Dissecting the role of the ubiquitin proteasome system in the pathogenesis and therapy of B-cell malignancies;2016-09-01;2021-08-31;;"B-cell malignancies are characterized by high levels of genomic instability, which critically contribute to their pathogenesis and evolution. Recently, the fundamental role of the ubiquitin proteasome system (UPS) in maintaining genome integrity has been appreciated. Two major new therapeutic modalities in B-cell malignancies, proteasome inhibitors and imunomodulatory drugs (IMiDs), target the UPS and demonstrate particular efficacy in multiple myeloma (MM) and mantle cell lymphoma (MCL), two incurable entities with poor prognosis. This suggests the presence of aberrant ubiquitylation events, whose identities have however remained mostly elusive. Our recent studies identify fundamental roles of orphan ubiquitin ligases of the Cullin Ring ligase family (CRLs) and their counterparts, the deubiquitylating enzymes (DUBs) in the cellular DNA damage response machinery, and characterize these candidates as novel oncogenes or tumour suppressors in MM and MCL. These findings provide the foundation for our hypothesis that deregulated ubiquitylation events involving CRLs and DUBs have a far reaching impact on the pathogenesis of B-cell malignancies and can serve as new therapeutic targets and biomarkers. We therefore propose a multistep strategy in which we will (1) characterize previously orphan CRLs and DUBs, which we have distinguished as candidate oncogenes and tumour suppressors in MM (FBXO3, USP24), MCL (FBXO25), or MM and MCL (CRBN), respectively; (2) decipher the global role of CRLs and DUBs in MM and MCL using defined genetic screens; (3) identify relevant substrates of CRLs/DUBs discovered in (2) using mass spectrometry; and (4) validate CRL/DUB candidates in preclinical mouse models and defined patient cohorts as to their disease relevance. We expect that our interdisciplinary approach will unravel the overall role of the UPS in the pathophysiology, evolution and treatment of B-cell malignancies.";1973255;1973255;ERC-2015-CoG;/ERC-COG;KLINIKUM RECHTS DER ISAR DER TECHNISCHEN UNIVERSITAT MUNCHEN;DE;;;;1;0;0;1;0;0 193927;642575;ALFF;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2014-ETN;H2020;The Algal Microbiome: Friends and Foes;2015-01-01;2018-12-31;;"Algal aquaculture is developing exponentially worldwide, with multiple applications in the food, chemical and pharmaceutical industries. Current research in algal biotechnology mostly focuses on metabolite discovery, aquaculture yield improvement and engineering bottlenecks. However, agronomical experience shows that controlling the interaction of land crops with mutualistic or pathogenic microbes is most critical to successful production. Likewise, controlling the microbial flora associated with algae (the 'algal microbiome') is emerging as the biggest biological challenge for their increased usage. Bacteria can control the morphogenesis of algae, while others are indispensable to algal survival. Pathogens are causing devastating diseases, the impact of which worsens with the intensification of aquaculture practices. Thus, the overarching aim of ALFF is to train 15 ESRs (researchers and technologists) within a multinational consortium, whilst bringing a scientific step-change in our understanding of these interactions, leading to the development of superior mass algal cultivation and biocontrol strategies. ALFF tackles: 1) the identification, taxonomy and utilisation of naturally-occurring algal symbionts and pathogens; 2) inter- and intra-species signalling and chemical ecology in aquaculture, natural environment and simplified systems (i.e. axenic cultures \/- symbionts); 3) and harnesses state of the art genomics, molecular, and biochemical techniques to characterise these interactions. A highly interdisciplinary team underpins an ambitious theoretical, field, hands-on training and research program. With the support of high profile institutions, ALFF foresees an exceptionally broad range of dissemination and outreach initiatives to help policy makers and the general public better understand the opportunities and issues relating to the sustainable use of our aquatic freshwater and marine resources, within and beyond the EU.";3794115,24;3794115,24;H2020-MSCA-ITN-2014;/MSCA-ITN-ETN;THE SCOTTISH ASSOCIATION FOR MARINESCIENCE LBG;UK;"OSTRAVSKA UNIVERZITA;UNIVERSITEIT GENT;PROVIRON HOLDING NV;FRIEDRICH-SCHILLER-UNIVERSITAT JENA;A4F ALGAFUEL SA;VIB;UNIVERSITAT KONSTANZ;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;APPLIED MATHS NV";"CZ;BE;DE;PT;FR";;1;0;0;1;0;0 205230;704227;Young-Italian 2015;CLOSED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Dangerous Masculinities: Young Men in Italian Cinema of the 1940s-1960s;2016-11-01;2018-10-31;;"The present project aims to examine Italian cinema during the twenty-year period from 1943 to 1963 in relation to the construction of the image of the young Italian man. The main goals are to understand how Italian cinema from the post-war period to the ‘economic boom’ gave substance to male national identities and to situate those identities within an emerging youth culture produced by the new consumer society in Italy. The proposal arises from two key observations: firstly, that the cinematic institution of the time and its gender representations depicted the crisis of traditional male authority at a time of great social change. In this respect, the figure of the young Italian man functions as a multi-faceted trope that challenges the patriarchal values embodied by older men. Secondly, that there has been a lack of studies of Italian cinematic masculinity, especially in the postwar period. From this perspective, the project intends to complement existing work in the fields of history and sociology on the emergence of Italian youth culture; it will uncover the repertoire of young masculine identities that cinema offered to audiences in these years, which were crucial to the negotiation of changing gender roles in the Italian cultural imaginary after the WWII until the present. The project is organised according to an integrated and interdisciplinary approach to the cinematic apparatus. The purpose is to look at the cinematic institution by analysing its textual and economic dimension (its ‘material’ component), and thus investigating the patterns of masculine representation offered by films and the related cultural industry; and by evaluating its cultural and social articulation (its ‘symbolic’ component), and thus focusing on the cinema audiences and their experiences with the film texts in relation to gender identity. The principal output will be a monograph on the figure of the young Italian man in the cinema of the long post-war period, the first of its kind.";183454,8;183454,8;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;UNIVERSITY OF BRISTOL;UK;;;;1;0;0;1;0;0 205219;702004;Operation Condor;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-GF;H2020;Operation Condor: Accountability for Transnational Crimes in Uruguay;2016-08-01;2019-07-31;;"Confronting past atrocities is essential to consolidate democracy and human rights protection. Truth and justice initiatives investigating crimes perpetrated at the national level have long been occurring. Yet, accountability for transnational crimes is a pending issue in scholarship and practice. This project fills this gap and addresses the transnational dimension of past atrocities in South America. In 1975, the dictatorships of Argentina, Bolivia, Brazil, Chile, Paraguay, and Uruguay established a secret transnational network of intelligence and counterinsurgency operations to persecute political opponents in exile called Operation Condor, kidnapping and murdering hundreds of people. The project aims to study transnational crimes, by focusing on Operation Condor’s Uruguayan victims, and probe the response of Uruguay’s national justice system to transnational atrocities. Uruguay was selected to analyse Operation Condor: one Uruguayan was kidnapped in each Condor country; thus, investigating its Uruguayan victims permits to also study the entire network and its modus operandi. The project creatively adopts a regional focus and uses data from recently opened archives. The broader question behind the research agenda is: how can we respond to atrocities that transcend state borders? Studying accountability for Operation Condor crimes will offer lessons of potential application to past and present forms of transnational crimes, such as the smuggling of migrants across the Mediterranean Sea. The outputs include three articles, a book, a policy brief, op-eds, a workshop for legal professionals, seminar and conference presentations, and training sessions for PhD students and early career researchers. The Fellowship will directly benefit Dr Lessa’s career prospects, equipping her with new skills, knowledge, and specialised training in archival research and analysis of case files, placing her at the forefront of her field as an established interdisciplinary researcher.";212463;212463;H2020-MSCA-IF-2015;/MSCA-IF-GF;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;UK;;;;1;0;0;1;0;0 215197;793778;MIDAS;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Microbial Degradation of Jellyfish-Derived Substrates;2018-07-02;2020-07-01;;The complex pool of dissolved organic matter (DOM) in the oceans is almost exclusively accessible to diverse members of microbial community carrying out different types of metabolism thereby, affecting biogeochemical state of the ocean. To predict the response of the marine ecosystem to natural and anthropogenic perturbations, a mechanistic understanding on the relation between the organic matter (OM) field and the metabolic network operated by the microbial community needs to be refined. One largely overlooked, but significant source of DOM are jellyfish. Regardless the debate over the accuracy of their reported global increase and on the true cause of the observed jellyfish fluctuations, the increase in their population size can have serious ecological and socio-economic consequences. As jellyfish blooms decay, sinking carcasses represent large quantities of detrital OM (jelly-OM), rich in proteins and hence, a high quality substrate for the ambient bacterial community. However, the exact processes and mechanisms of bacterial jelly-OM degradation remain unknown. In the MIDAS project, an integrated interdisciplinary approach will be applied to characterize the composition of jelly-OM at the molecular level and the metabolic network operated by jelly-OM degrading bacterial communities using state-of-the-art analytical tools (ultra-high resolution mass spectrometry) and cutting edge –omics techniques combining emerging fields of marine metaproteomics and exoproteomics. This knowledge will enable us understanding the implications of jellyfish blooms on biogeochemical cycles in coastal seas.;178156,8;178156,8;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;UNIVERSITAT WIEN;AT;;;;1;0;0;1;0;0 203973;708351;NANOTER;CLOSED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Development of Ultra-Sensitive Nanotherapeutic Anticancer Agents for Boron Neutron CaptureTherapy;2016-10-01;2018-09-30;;"One of the major challenges in modern society is the early diagnosis and treatment of diseases. Cancer is one of the most relevant diseases worldwide because of its incidence, prevalence and mortality. Current cancer treatments do not only kill cancer cells but also healthy tissue. In order to overcome this situation, more effective and selective treatments are necessary. Neutron capture therapy (NCT) is a biologically targeted form of radiotherapy which exploits the potential of some specific isotopes to capture thermal neutrons producing charged particles suitable for the treatment of cancer. The range of the particles produced in NCT can be limited to the size of one cell. Therefore, provided that neutron capture species are selectively delivered to tumour cells, no damage will occur to the surrounding healthy tissue. Novel delivery agents suitable for NCT must be investigated that will allow a localised cancer treatment. NANOTER presents an innovative and previously unexplored approach to develop ultra-sensitive nanotherapeutic agents for NCT. Neutron capture species will be sealed in the interior of carbon nanocapsules (biocompatible closed-ended carbon nanotubes) and their behaviour against neutron irradiation experiments will be investigated and compared against other current materials for NCT. The interdisciplinary approach taken to develop the proposed research programme is expected to contribute to the development of alternative and previously unexplored nanoplatforms for NCT, enhancing the performance of current delivery agents for NCT.";170121,6;170121,6;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS;ES;;;;1;0;0;1;0;0 204157;692995;BAYNET;SIGNED;H2020-EU.1.1.;ERC-ADG-2015;H2020;Bayesian Networks and Non-Rational Expectations;2016-07-01;2021-06-30;;'This project will develop a new framework for modeling economic agents having 'boundedly rational expectations' (BRE). It is based on the concept of Bayesian networks (more generally, graphical models), borrowed from statistics and AI. In the framework's basic version, an agent is characterized by a directed acyclic graph (DAG) over the set of all relevant random variables. The DAG is the agent's 'type' – it represents how he systematically distorts any objective probability distribution into a subjective belief. Technically, the distortion takes the form of the standard Bayesian-network factorization formula given by the agent's DAG. The agent's choice is modeled as a 'personal equilibrium', because his subjective belief regarding the implications of his actions can vary with his own long-run behavior. The DAG representation unifies and simplifies existing models of BRE, subsuming them as special cases corresponding to distinct graphical representations. It captures hitherto-unmodeled fallacies such as reverse causation. The framework facilitates behavioral characterizations of general classes of models of BRE and expands their applicability. I will demonstrate this with applications to monetary policy, behavioral I.O., asset pricing, etc. I will extend the basic formalism to multi-agent environments, addressing issues beyond the reach of current models of BRE (e.g., formalizing the notion of 'high-order' limited understanding of statistical regularities). Finally, I will seek a learning foundation for the graphical representation of BRE, in the sense that it will capture how the agent extrapolates his belief from a dataset (drawn from the objective distribution) containing 'missing values', via some intuitive 'imputation method'. This part, too, borrows ideas from statistics and AI, further demonstrating the project's interdisciplinary nature.';1379288;1379288;ERC-2015-AdG;/ERC-ADG;UNIVERSITY COLLEGE LONDON;UK;TEL AVIV UNIVERSITY;IL;;1;0;0;1;0;0 203406;692692;GIANTSYN;SIGNED;H2020-EU.1.1.;ERC-ADG-2015;H2020;Biophysics and circuit function of a giant cortical glutamatergic synapse;2017-03-01;2022-02-28;;"A fundamental question in neuroscience is how the biophysical properties of synapses shape higher network computations. The hippocampal mossy fiber synapse, formed between axons of dentate gyrus granule cells and dendrites of CA3 pyramidal neurons, is the ideal synapse to address this question. This synapse is accessible to presynaptic recording, due to its large size, allowing a rigorous investigation of the biophysical mechanisms of transmission and plasticity. Furthermore, this synapse is placed in the center of a memory circuit, and several hypotheses about its network function have been generated. However, even basic properties of this key communication element remain enigmatic. The ambitious goal of the current proposal, GIANTSYN, is to understand the hippocampal mossy fiber synapse at all levels of complexity. At the subcellular level, we want to elucidate the biophysical mechanisms of transmission and synaptic plasticity in the same depth as previously achieved at peripheral and brainstem synapses, classical synaptic models. At the network level, we want to unravel the connectivity rules and the in vivo network function of this synapse, particularly its role in learning and memory. To reach these objectives, we will combine functional and structural approaches. For the analysis of synaptic transmission and plasticity, we will combine direct preand postsynaptic patch-clamp recording and high-pressure freezing electron microscopy. For the analysis of connectivity and network function, we will use transsynaptic labeling and in vivo electrophysiology. Based on the proposed interdisciplinary research, the hippocampal mossy fiber synapse could become the first synapse in the history of neuroscience in which we reach complete insight into both synaptic biophysics and network function. In the long run, the results may open new perspectives for the diagnosis and treatment of brain diseases in which mossy fiber transmission, plasticity, or connectivity are impaired.";2677500;2677500;ERC-2015-AdG;/ERC-ADG;INSTITUTE OF SCIENCE AND TECHNOLOGYAUSTRIA;AT;;;;1;0;0;1;0;0 203822;703381;ECOTRAIT;CLOSED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Understanding the links between functional traits and ecological processes in lake Arcellinida (testate amoebae) (‘ECOTRAIT’);2016-10-01;2018-09-30;;"Testate amoebae, shelled unicellular eukaryotes, are common in freshwater and moist terrestrial environments. Their shells preserve well in the fossil record and species assemblages have been shown to be sensitive indicators of water quality change, and thus useful in environmental monitoring. Whilst the ecology of the group is reasonably well understood, a determination of their role in specific ecosystem processes has been hampered by taxonomic uncertainties. As the living cell quickly decays after death, taxonomic divisions have relied on shell morphology. This approach is problematic as genetic analysis has shown that some species display morphological plasticity, partially in response to environment, whilst other specimens with similar morphologies have been demonstrated to be distinct ‘cryptic’ species. This project will utilise techniques used by the two research communities to develop more refined methodologies to characterize test morphology (e.g., notably functional trait analysis) to provide a powerful new framework for understanding microbial food-webs and community responses to ecological stressors over multiple time-scales. Specifically, the project will apply these interdisciplinary methodologies to examine the controls on morphology in Arcellenida, the dominant testate amoebae found in lakes to: 1. examine causes of functional trait variability in modern and palaeolimnological settings; 2. develop novel biometric trait delimitation approaches using SEM imagery and 3D imaging software; 3. use genetic sequencing on select morphospecies, to test the hypothesis that variations in shell morphology are a response to environment; 4. evaluate the significance of trait-based approaches for understanding temporal changes in species composition. This research will significantly contribute to the training of the researcher, enhancing future career opportunities, as well as expanding the collaborative research network and skills of the host.";183454,8;183454,8;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;THE QUEEN'S UNIVERSITY OF BELFAST;UK;;;;1;0;0;1;0;0 202924;705194;SeQuCom;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Secure Quantum Communication and Computation;2017-02-06;2019-02-05;;"Quantum Theory is one of the greatest scientific revolutions of the twentieth century. During the last decades, it has become apparent that the tools provided by quantum mechanics can be used in many fields, such as cryptography, algorithms, game theory, and even biology. This is because quantum systems exhibit an intrinsic randomness that can be exploited in order to significantly boost computational performance, increase security of communications and in general achieve tasks that are impossible with purely classical means. On the other hand, the use of quantum technologies in future telecommunication networks, raises important questions on the security of the currently deployed protocols since quantum adversaries will be able to use quantum effects to break widely-deployed cryptosystems (e.g. RSA). The scientific aim of the proposed research project is to build the essential components for secure quantum communication and computing in realistic environments. It stands at the interface between quantum theory and experiments, focusing on the effect of the experimental environment on the implementation and security of different quantum computational models and protocols. It is expected to pave the way for large-scale quantum cloud computing, so that users can store and process their data on a network using powerful quantum servers, therefore providing a more effective way for computing and communication. The proposed project is highly innovative and interdisciplinary, and it will play an essential role in my career development, since it will allow me to work closely with researchers from different fields and acquire both key scientific and complementary skills.";183454,8;183454,8;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;UNIVERSITY COLLEGE LONDON;UK;;;;1;0;0;1;0;0 203332;713482;ALERT;SIGNED;H2020-EU.1.3.4.;MSCA-COFUND-2015-DP;H2020;Local Training Network on Novel Tailor-Made Antimicrobials and Delivery Strategies From Synthesis towards Clinical Applications;2016-05-01;2021-04-30;;The current overuse of antibiotics is leading to the emergence of multidrug resistant (MDR) bacteria. These MDR pathogens continue to evolve at a terrifying rate and confer resistance to most or all presently available antibacterial treatments. Antimicrobial resistance is an eminent global problem that calls for an integrated approach that surpasses national borders, sectors, and disciplines. The COFUND ALERT programme addresses this call by establishing a dedicated doctoral training programme with an international, interdisciplinary and inter-sectoral focus. Nineteen excellent Early Stage Researchers (ESRs) will be employed at the University of Groningen (RUG). ALERT is based at RUG but is tightly connected with multiple international academic and private partner organisations, each providing complementary research or training. ALERT aims to develop the best practices in high quality training and research. ALERT achieves this through advanced multidisciplinary research training extended with development of dedicated transferable and entrepreneurial skills. ESRs will develop novel antimicrobial drug candidates through chemical, biotechnological and nanotechnological synthesis and subsequent in vivo testing. All ALERT Principal Investigators have ample experience with supervising PhD students, which ensures an attractive and vibrant research environment for the ESRs. In addition, access to excellent modern research facilities is guaranteed. Thus, the ALERT programme creates an optimal research and training environment that is far greater than the sum of its individual parts. ALERT’s long-term ambitions are to establish a strong and coherent international network that links together highly skilled young researchers as well as established scientists, who far beyond the funding period will continue to inspire each other to excel in antimicrobial resistance research in order to tackle the antimicrobial challenge.;3976320;1988160;H2020-MSCA-COFUND-2015;/MSCA-COFUND-DP;RIJKSUNIVERSITEIT GRONINGEN;NL;;;;1;0;0;1;0;0 203253;685474;METAFLUIDICS;SIGNED;H2020-EU.2.1.4.;BIOTEC-6-2015;H2020;Advanced toolbox for rapid and cost-effective functional metagenomic screening - microbiology meets microfluidics.;2016-06-01;2020-05-31;;"Metagenomes comprise enormous reservoirs coding for proteins with useful activities. Unfortunately, harvesting this reservoir is difficult, because useful candidates are rare and hidden in an overwhelming majority of irrelevant genes. Screening campaigns of metagenomic libraries thus require massive capital-expenditure for robotic systems and much manpower, making them expensive, slow and available to very few users. To enable valorisation of the potential of the metagenome, this project assembles an interdisciplinary and intersectoral consortium that will integrate a range of technologies into a platform designed to beat the odds of identifying library hits faster, more efficiently and by a wider user base. Exploration and exploitation of the metagenome will be made faster and more successful by (i) ultrahigh-throughput screening in picoliter droplets that dramatically lowers the cost per assay to well below 0.01 cents and allows throughput of 10e7 assays per hour; (ii) workflows that streamline and increase the yield of library construction and functional expression and (iii) workflows for efficient bioinformatic analysis of hits based on user-friendly software solutions for metagenome analysis. Emphasis is put on technologies that are straightforwardly implemented in non-specialist labs, maximising the impact of METAFLUIDICS. This platform will be used to identify enzymes for biosynthesis of therapeutic small molecules, for green bioenergy conversion, bioremediation, food chemistry and other industrial applications";8808363;8808363;H2020-LEIT-BIO-2015-1;/RIA;UNIVERSIDAD AUTONOMA DE MADRID;ES;"UNIVERSIDAD DE ALICANTE;BIOILIBERIS RESEARCH AND DEVELOPMENT SL;THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;STIFTELSEN SINTEF;NOVOZYMES A/S;INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE TOULOUSE INSAT;SINTEF AS;AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS;QIAGEN AARHUS AS;CENTRO DE NEUROCIENCIAS E BIOLOGIACELULAR ASSOCIACAO;DROP-TECH LTD;PROZOMIX LIMITED;NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU";"ES;UK;NO;DK;FR;PT";;1;0;0;1;0;0 202884;704479;Legitimacy;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-GF;H2020;Legitimacy, Sovereignty and the Public Sphere;2017-03-01;2020-04-30;;"The goal of the research is to redefine the interrelations between the concepts of legitimacy, sovereignty, the public sphere and democracy in order to develop a conception of a more inclusive and participatory public sphere. The problems of participation in and inclusivity of the public sphere relate to recent trends of globalisation and democratic development in general. As for the latter it has been argued that democracy is hijacked by corporate interests and party bureaucracies that make decisions in their back rooms, excluding all public discussion, and as for the former, we can observe how globalisation brings together different peoples, cultures, religions, highlighting the question of openness to and acceptance of differences. This research project proceeds from understanding that tackling these issues means to deal with the problems of inclusivity and participation in the public sphere. This project differs from various re-conceptualisations of the public sphere or sovereignty that have been offered in response to these concerns. It returns to the original condition of possibility of the concept of the public sphere: my argument is that the mentioned problems with inclusivity and participation emanate from the unfinished conceptual separation between state and society. I argue further that the idea of legitimacy has to be tackled, if this conceptual separation is to be brought to its conclusion. My theoretical approach to these issues will be a conceptual analysis informed by Derridean deconstruction. This project is innovative as it is interdisciplinary in using conceptual tools of philosophy to reinterpret terms which are in use in our everyday political practice. The process of carrying out the research plan that also foresees publishing four scholarly articles and the completion of one book manuscript will significantly develop further my skills and knowledge, making me better equipped to contribute to European science.";251857,8;251857,8;H2020-MSCA-IF-2015;/MSCA-IF-GF;QUEEN MARY UNIVERSITY OF LONDON;UK;;;;1;0;0;1;0;0 202798;702869;EFFECT;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Effective environmental policies in Europe in the context of rebound effects;2017-05-01;2019-04-30;;"European policymakers are increasingly concerned about the unsatisfactory outcomes of efforts to harmonise economic growth and welfare with environmental quality, in particular due to the so-called rebound effects. The main objective of the EFFECT project is to develop innovative methods to identify and quantify key rebound effects, and assess their potential to impede the achievement of environmental targets in Europe. Some specific research objectives are: (1) review and classification of key environmental policies and targets in the EU and Member States in the context of rebound effects; (2) improvement of theoretical and methodological aspects of macroeconomic models used in rebound effect studies by integrating the ‘environmental rebound effect’ perspective; (3) assessment of the impact of rebound effects via EU and country-level ex post assessment of past key environmental policies and ex ante assessment of future policy scenarios and (4) proposal of recommendations to achieve net environmental savings from environmental policies, including optimal combinations and configurations, as well as optimal levels of welfare and economic development and equality. To attain such objectives, the EFFECT project will design an innovative analytical framework by combining an interdisciplinary perspective with micro and macro-level aspects of rebound effects. Such framework would allow a more comprehensive and scientifically sound study of the interplay between rebound effects and policy. In the context of the pursuit of a sustainable economic growth in Europe, this project can aid European policymakers in the design of effective environmental policies. Furthermore, the development of innovative and state-of-the-art analytical frameworks aimed at tackling exceptional societal challenges such as climate change resonates with the ambition of putting Europe’s in-house science and researchers at the forefront of worldwide scientific excellence.";183454,8;183454,8;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;UNIVERSITY COLLEGE LONDON;UK;;;;1;0;0;1;0;0 193899;642294;TCCM;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2014-EJD;H2020;Theoretical Chemistry and Computational Modelling;2015-01-01;2018-12-31;;Theoretical Chemistry and Computational Modelling (TCCM) is emerging as a powerful tool to help in the rational design of new products and materials for pharmaceutical, chemical, energy, computer, and new-materials industries. To achieve this goal, it is necessary to go beyond the traditional electronic structure studies, and merge complementary techniques that are normally not available at a single research group. The research programme of the TCCM-EJD aims at applying computational modelling to problems demanded by the industry and with high societal relevance, namely Materials with special properties, Biomolecules for new therapies and Energy storage. The objective of the Joint Doctorate is to prepare future research leaders, able to develop and use multidisciplinary computational techniques (methods and software), with solid communication skills, with many contacts established through the intensive relationship with worldwide leading researchers of 12 European universities and 14 additional partners, including 7 industrial and spin-off companies. A Joint Doctorate in TCCM is already operative since 2011, based on a fully participative scientific discussion and assessment of all research projects with a clear interdisciplinary character and the direct participation of the non-academic sector. The training programme puts the emphasis in common training, including 3 annual International Workshops, 3 schools on High Performance Computing and 3 tutorials in new computer codes. Career development opportunities are enhanced with regular inter-sectoral activities, transferable skill education and career coaching.;3785867,52;3785867,52;H2020-MSCA-ITN-2014;/MSCA-ITN-EJD;UNIVERSIDAD AUTONOMA DE MADRID;ES;"UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6;UNIVERSITAT WIEN;UNIVERSITAT DE VALENCIA;UNIVERSITA DI PISA;UNIVERSITAT DE BARCELONA;UNIVERSIDADE DO PORTO;RIJKSUNIVERSITEIT GRONINGEN;UNIVERSITA DEGLI STUDI DI PERUGIA;UNIVERSITE PAUL SABATIER TOULOUSE III;KATHOLIEKE UNIVERSITEIT LEUVEN;UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA;SORBONNE UNIVERSITE";"FR;AT;ES;IT;PT;NL;BE";;1;0;0;1;0;0 201356;705697;REINVENT;CLOSED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Re-inventory-ing Heritage: Exploring the potential of public participation GIS to capture heritage values and dissonance;2016-09-01;2018-08-31;;This research critically addresses the challenges pertaining to the management of cultural heritage in contested cross-border contexts in Europe. The cultural landscape of Derry~Londonderry, located in the North West of Ireland, provides the lens through which expressions of heritage values and dissonance, participatory practices in cultural heritage management, and the application of Geographical Information Systems (GIS) to mapping heritage a cross-border basis, are explored. The interdisciplinary research will result in the first cross-border ‘cultural heritage atlas’ on the island of Ireland, and the development of a public participation GIS (PPGIS) methodology and tool aimed at capturing the plurality of heritage values ascribed by diverse communities at multiple spatial scales. The knowledge generated will be embedded within local cultural heritage management and spatial planning networks and will also inform policies and practices. The proposed training-through-research will significantly enhance my skills and competencies as an experienced researcher, advancing previous cutting-edge work on heritage values and cross-border spatial planning, and equipping me with a range of new research methods, particularly ICT- and public participation-related, that are central to future innovation in cultural heritage management in Europe. Maynooth University, given the quality of the supervisory arrangements and the location of several research resources actively engaged in cross-border cooperation, provides an optimal setting for this research and for progressing to the next stage of my research career.;175866;175866;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;NATIONAL UNIVERSITY OF IRELAND MAYNOOTH;IE;;;;1;0;0;1;0;0 201227;704281;CCDSA;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Control of cell division in Sulfolobus acidocaldarius;2017-01-01;2018-12-31;;Archaea and eukaryotes share conserved regulators such as ESCRTIII proteins that are involved in fundamental aspects of eukaryotic cell division, a finding that assumes particular importance in the context of widely accepted models for the evolution of eukaryotes from an ancestral archaeal host. Yet the mechanisms by which archaea regulate cell division- in the absence of nuclei, organelles and a rigid cell wall- are poorly understood. The research programme proposed here aims to fill this gap in our understanding by investigating the control and coordination of cell division in the model crenarchaeote Sulfolobus acidocaldarius. We will use super-resolution imaging in combination with cell sorting and electron cryotomography to characterize cell cycle progression in Sulfolobus at unprecedented resolution. We will leverage a novel in-house high-temperature live imaging platform and proteins labeled with thermostable GFP to dissect the molecular coupling between the key processes of chromosome segregation, membrane invagination, and abscission. Further, we will use forward genetics, whole-genome sequencing and comparative genomics to identify novel cell division regulators that are conserved in eukaryotes. We expect this detailed characterization of cell division in cells without organelles or a nucleus to have broad implications for our understanding of the origins of the more elaborate mechanisms found in extant eukaryotes. Moreover, in the future we expect the knowledge gained and interdisciplinary approaches developed here to be applicable for the study of Loki, the recently identified closest archaeal relative of eukaryotes, and for furthering the industrial utility of hyperthermophilic archaea.;195454,8;195454,8;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;UNIVERSITY COLLEGE LONDON;UK;;;;1;0;0;1;0;0 201293;705104;Exile and Technology;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-GF;H2020;Austro-German exile in America 1930-45: interrogating the relationship between science, technology and modern selfhood in cultural and musical discourses.;2016-09-01;2019-11-30;;This project examines the relationship between technology, selfhood, and modernity in the context of the music and thought of Austrian and German émigré musicians and cultural theorists in America from 1930 to 1945. The project looks beyond the boundaries of the nation state and the nexus of composer and musical work that tend to structure musicological enquiry. Instead, transnational historical methodologies will be used alongside primary archival research to join a timely conversation in musicology about the intersections between histories of music and science. In the era 1930-45, (Austro-)Germany and America were scientific powerhouses. Against the backdrop of mounting political turmoil, both generated ethically controversial scientific and technological research simultaneously liberating and malevolent: atomic technology, cosmology, radar, eugenics, transportation innovations. Technology necessarily shapes ideas of selfhood, and the mass displacement of Austrian and German intellectuals to the US after the rise of the National Socialists created a ‘culture of exile’ in which, as émigrés integrated within the new context, diverse attitudes to the relationship between science, technology, and formulations of the self began to interweave. Using musical collaborations, spectacles, and events to illuminate and explore the range and ambivalence of those attitudes, the project will furnish a more finely grained historical understanding of the disconnections between Germanic and American relationships to technology and selfhood in the period. The research outcomes during the fellowship will be a monograph, and two articles as part of substantial work on a second book. A further key objective will be to establish an international interdisciplinary academic network in the US, UK, and Germany for collaborative projects and conferences exploring technological and cultural/musical discourse, exile, and international mobility in the first half of the twentieth century.;251857,8;251857,8;H2020-MSCA-IF-2015;/MSCA-IF-GF;ROYAL HOLLOWAY AND BEDFORD NEW COLLEGE;UK;;;;1;0;0;1;0;0 200959;701621;MULTISIMO;CLOSED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;MULTImodal and MULTIparty Social Interactions MOdelling;2016-09-01;2018-08-31;;The project addresses the modelling of multimodal communicative human behaviour during natural interactions in multiparty settings and specifically the conversational and feedback strategies of the interaction participants in terms of attention, engagement and conflict management. The knowledge base for this modelling problem will be a collection of human-human interaction recordings to be acquired through a concise experimental protocol and state-of-the-art equipment. The communicative behavior will be analysed in multimodal signals, including facial expressions, gaze and prosodic cues that provide information about social interaction management and speakers’ attitudes. This information becomes more complex in group interactions, where a management mechanism will be discovered and modelled. These low-level signals will be examined in relation to their timing and sequence to infer and model high-level signals of attention, engagement and conflict, and subsequently implement modules to feed existing HCI interfaces such as dialogue systems or avatars. The implementation of such novel models will allow for the creation of more sophisticated human-like agent-based interfaces of high quality communication experience, especially in scenarios where social and cognitive skills, in addition to the communicative ones, are crucial for the success of the interaction, i.e. in the education, customer care domains and web applications requiring interfaces triggered by human communication. The project builds on the strengths of the applicant in multimodal communication and language technology, and combines these with new training in intelligent systems and human-computer interaction to support a new research direction and to strengthen cross-European collaboration. The host provides an excellent supportive environment conducive to the interdisciplinary research envisaged in the project and the training objectives of the fellowship in view of the applicant’s career development.;175866;175866;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN;IE;;;;1;0;0;1;0;0 200945;701464;SocialBrain;CLOSED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Brain growth under social pressure: mathematical modelling of brain growth when individuals face social challenges;2016-10-01;2018-10-15;;"Growing and maintaining a large brain entails substantial energetic costs. A large brain can evolve if costs are compensated by benefits from associated cognitive abilities. Leading hypotheses for brain evolution consider benefits arising from the solution of ecological and social problems. However, progress has been hindered by the unavailability of mathematical theory generating testable hypotheses from known causes. I will develop testable mathematical models that yield quantitative predictions for brain mass through ontogeny when individuals evolve under social pressures. The goal is to assess the relative role of the social and ecological hypotheses in brain evolution, particularly in humans. I will formulate the models using elements of metabolic theory and life history theory, and the analysis will require methods from optimal control and differential game theory. This is a strongly interdisciplinary research project, and I will ensure its success by working with leaders in the respective fields of social evolution theory (Dr Andy Gardner, St Andrews), cognition (the world-class multi-departmental team at St Andrews), and differential game theory (Prof Maurizio Falcone, Sapienza). This work thus brings together a diversity of state-of-the-art elements and proposes an innovative, challenging, and important project, to produce a novel and readily usable tool to study brain evolution.";195454,8;195454,8;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;THE UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS;UK;;;;1;0;0;1;0;0 201135;703366;SELECTRON;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Selective production of valuable chemicals by electro-nano-catalysts;2017-04-27;2019-04-26;;To minimise the impact of mankind on the environment while ensuring economically viable industrial activities, greener processes are needed. In particular, developing selective synthesis routes of valuable chemicals with limited waste in the production is a major challenge faced by industry. As a case study, Haldor Tops?e, world expert in catalysis and secondment host in the project, aims to produce the valuable chemical dimethyl carbonate (DMC) without CO2 emission. Within this framework, the SELECTRON project will develop an electro-nano-catalyst for the selective and green production of DMC from methanol and CO. First, a nanotoolbox and a new synthesis route will be developed using a microwave reactor synthesis to provide Pt, Au, Ag, Cu nanocatalysts with controlled shape and structure. Second, the electrocatalytic properties of these catalysts for production of dimethyl carbonate will be assessed for the first time by state-of-the-art electrochemical and chemical characterisation but also more advanced technique like spectro-electrochemistry in parallel to theoretical simulation. Based on the knowledge gained on the electrocatalytic mechanism, a stable and selective catalyst will finally be produced. This highly interdisciplinary project will benefit from my strong background in nanomaterials design and synthesis, electrochemistry and catalysis, the complementary expertise of the host group in spectro-electro-chemistry, expertise of collaborators in theoretical simulation, and the strong commitment of Haldor Tops?e to bridge the gap academia-industry in order to develop a green production method for valuable chemicals like DMC. I will develop the required skills to become an independent expert in the emerging field of green production of valuable chemicals by electro-nano-catalysis, thus fulfilling H2020’s goal to generate leading expertise and innovation in green technologies.;200194,8;200194,8;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;KOBENHAVNS UNIVERSITET;DK;;;;1;0;0;1;0;0 201015;702128;microMAGNETOFLUIDICS;CLOSED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;3D-printed magnetic microfluidics for applications in life sciences;2016-06-01;2018-05-31;;"The field of microfluidics is providing answers to several key questions in biology. Specifically, microfluidic single-cell analysis yields important insights into the heterogeneity of cells that is crucial for cancer research, regenerative medicine and drug development. Microfluidics has also emerged as a powerful tool to study single bacteria and to address questions concerning antibiotic persistence and the role of the microbiome in protecting against modern plagues such as cancer, autoimmune diseases and obesity. Despite its great potential, microfluidic technologies have not been widely adopted in mainstream biomedical research since they require a great deal of external equipment, which is often difficult to operate by untrained personnel. The aim of this proposal is to simplify fluid handling and single-cell studies by developing a microfluidic device that includes magnetic microvalves. These microvalves can be wirelessly actuated to generate compartments and isolate single cells. The magnetic microvalves will be integrated by means of a very recently available lithographic tool based on two-photon polymerization (2PP) with sub-diffraction limit resolution, which enables the fabrication of polymer-based 3D micro- and nano-architectures. The microMAGNETOFLUIDICS project is strongly interdisciplinary in nature where physics, materials science, and biology are strongly intertwined. The innovative character of this proposal is unprecedented since no previous studies have been reported on 3D-printed magnetic microvalves operating within a microfluidic channel. The topic of the project is timely because it promotes the use of microfluidics among biologists and bacteriologists for decrypting cellular mechanisms at a single-cell level.";187419,6;187419,6;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH;CH;;;;1;0;0;1;0;0 202574;681257;eLightning;SIGNED;H2020-EU.1.1.;ERC-CoG-2015;H2020;Lightning propagation and high-energy emissions within coupled multi-model simulations;2016-06-01;2021-05-31;;"More than 250 years after establishing the electrical nature of the lightning flash, we still do not understand how a lightning channel advances. Most of these channels progress not continuously but in a series of sudden jumps and, as they jump, they emit bursts of energetic radiation. Despite increasingly accurate observations, there is no accepted explanation for this stepped progression. This proposal addresses this open question. First, we propose a methodological breakthrough that will allow us to tackle the main bottleneck in the theoretical understanding of lightning: the wide disparity between length-scales within a lightning flash. We plan to apply techniques that have succeeded in other fields, such as multi-model coupled simulations and moving-mesh finite elements methods. Acting as a computational microscope, these techniques will reveal the small-scale electrodynamics around a lightning channel. We will then apply these techniques to elucidate the intertwined problems of lightning channel stepping and thunderstorm-related high-energy emissions. The main hypothesis that we will test is that stepping is due to the formation of low-conductivity spots within the filamentary-discharge region that surrounds a lightning channel. This idea is motivated by observations from high-altitude atmospheric discharges. By resolving the small-scale dynamics, with our numerical method, we will also test hypothesis for high-energy emissions from the lighting channel, which crucially depend on the microscopic distribution of electric fields. This interdisciplinary proposal, straddling between geophysics and gas discharge physics, seeks a double breakthrough: the methodological one of building multi-scale lightning simulations and the hypothesis-driven one of finding out the reason for stepping. If it succeeds, it will achieve a leap forward in our knowledge of lightning, undoubtedly one of the greatest spectacles in our planet's repertoire.";1960825,51;1960825,51;ERC-2015-CoG;/ERC-COG;AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS;ES;;;;1;0;0;1;0;0 200906;700833;OUTCROSS;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Operator semigroup techniques in the control of delay systems;2016-11-01;2018-10-31;;"The purpose of this project is to apply operator theory to evolution equations in order to investigate fundamental properties of infinite dimensional dynamical systems with delay in state variables. Radoslaw Zawiski will pursue this goal within the Analysis Group at the School of Mathematics of the University of Leeds, under the supervision of Professor Partington. This interdisciplinary project searches for the answer to the question of necessary and sufficient conditions for admissibility and controllability of an infinite dimensional dynamical system. It also scrutinises weighted forms of admissibility and controllability for a delay system with problems involving the Dirichlet-type norms. With the above, this project goes beyond the state-of-the-art utilising innovative operator semigroup techniques, in particular Carleson embeddings involving sectorial measures and Toeplitz/Hankel operators, to obtain results in an underdeveloped area of state delayed infinite dimensional systems. Concurrently, this project crosses current frontiers in control theory of such systems, setting new level and worldwide standard by giving a great insight into the nature of evolution equations. By fulfilling its purpose, this project helps the European scientific community to maintain its leading role in operator theory and control theory, adding to this topic a relevant set of techniques specifically designed for state delayed evolution equations. In this respect, the fellowship supports Radoslaw Zawiski’s career development by providing him the right environment to attain the proposed research goals. Dr Zawiski will reach the full maturity as a leading researcher, with the solid background and possibilities to significantly contribute to the development of operator theory and control theory.";195454,8;195454,8;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;UNIVERSITY OF LEEDS;UK;;;;1;0;0;1;0;0 200813;685817;HISENTS;SIGNED;H2020-EU.2.1.2.2.;NMP-29-2015;H2020;High level Integrated SEnsor for NanoToxicity Screening;2016-04-01;2019-03-31;;The HISENTS vision is to address the problem of the dearth of high-quality tools for nano-safety assessment by introducing an innovative multimodular high throughput screening (HTP) platform including a set of individual modules each representing a critical physiological function connected and integrated in a hierarchical vectorial manner by a microfluidic network. The increase of the capacity to perform nano-safety assessment will be realised by innovative instrumentation developments for HTP and high content analysis (HCA) approaches. Toxicogenomics on chip is also one embedded objective. Our interdisciplinary approach focuses on tools to maximise the read-across and to assess applicable endpoints for advanced risk assessment of nanomaterials (NM). The main goal is thus to establish individual chip-based microfluidic tools as devices for (nano)toxicity screening which can be combined as an on-line HTP platform. Seven different chip-based sensor elements will be developed and hierarchically combined via a flow system to characterise toxicity pathways of NM. The HISENTS platform allows the grouping and identifying of NM. Parallel to the screening, the pathway and interaction of NM in biological organisms will be simulated using the physiologically based pharmacokinetic (PBPK) model. Using the different sensor modules from the molecular to cell to organ level, HISENTS can input quantitative parameters into the PBPK model resulting in an effective pathway analysis for NM and other critical compounds. The developed platform is crucial for realistic nano-safety assessment and will also find extensive application in pharmaceutical screening due to the flexible modifications of the HTP platform. The specific objective is the development of a multimodular HTP platform as new a screening tool for enhancing the efficiency of hazard profiling. Currently, no such flexible, easy-to-use screening platform with flexibly combinable chip-based sensors is available on the market.;6332825;6332825;H2020-NMP-2015-two-stage;/RIA;UNIVERSITY OF LEEDS;UK;"SLOVENSKA TECHNICKA UNIVERZITA V BRATISLAVE;TECHNISCHE UNIVERSITAET WIEN;FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.;FUNDACIO INSTITUT CATALA DE NANOCIENCIA I NANOTECNOLOGIA;NORSK INSTITUTT FOR LUFTFORSKNING STIFTELSE;TEL AVIV UNIVERSITY;Blueprint Product Design Ltd;BIOMEDICINSKE CENTRUM SLOVENSKEJ AKADEMIE VIED;USTAV EXPERIMENTALNEJ ONKOLOGIE SLOVENSKEJ AKADEMIE VIED;UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK;UNIVERSITAT DES SAARLANDES";"SK;AT;DE;ES;NO;IL;UK;IE";;1;0;0;1;0;0 200161;679849;SponGES;SIGNED;"H2020-EU.3.5.;H2020-EU.3.2.";BG-01-2015;H2020;Deep-sea Sponge Grounds Ecosystems of the North Atlantic: an integrated approach towards their preservation and sustainable exploitation;2016-03-01;2020-02-29;;The objective of SponGES is to develop an integrated ecosystem-based approach to preserve and sustainably use vulnerable sponge ecosystems of the North Atlantic. The SponGES consortium, an international and interdisciplinary collaboration of research institutions, environmental non-governmental and intergovernmental organizations, will focus on one of the most diverse, ecologically and biologically important and vulnerable marine ecosystems of the deep-sea - sponge grounds – that to date have received very little research and conservation attention. Our approach will address the scope and challenges of EC’s Blue Growth Call by strengthening the knowledge base, improving innovation, predicting changes, and providing decision support tools for management and sustainable use of marine resources. SponGES will fill knowledge gaps on vulnerable sponge ecosystems and provide guidelines for their preservation and sustainable exploitation. North Atlantic deep-sea sponge grounds will be mapped and characterized, and a geographical information system on sponge grounds will be developed to determine drivers of past and present distribution. Diversity, biogeographic and connectivity patterns will be investigated through a genomic approach. Function of sponge ecosystems and the goods and services they provide, e.g. in habitat provision, bentho-pelagic coupling and biogeochemical cycling will be identified and quantified. This project will further unlock the potential of sponge grounds for innovative blue biotechnology namely towards drug discovery and tissue engineering. It will improve predictive capacities by quantifying threats related to fishing, climate change, and local disturbances. SpongeGES outputs will form the basis for modeling and predicting future ecosystem dynamics under environmental changes. SponGES will develop an adaptive ecosystem-based management plan that enables conservation and good governance of these marine resources on regional and international levels.;10275365,25;9994302,75;H2020-BG-2015-2;/RIA;UNIVERSITETET I BERGEN;NO;"UNIVERSIDADE DO MINHO;INSTITUTO ESPANOL DE OCEANOGRAFIA;FOOD AND AGRICULTURE ORGANIZATION OF THE UNITED NATIONS FAO;ECOLOGY ACTION CENTRE;DALHOUSIE UNIVERSITY;STICHTING NIOZ, KONINKLIJK NEDERLANDS INSTITUUT VOOR ONDERZOEK DER ZEE;NATURAL HISTORY MUSEUM;UPPSALA UNIVERSITET;STUDIO ASSOCIATO GAIA SNC DEI DOTTORI ANTONIO SARA E MARTINA MILANESE;HELMHOLTZ-ZENTRUM GEESTHACHT ZENTRUM FUR MATERIAL- UND KUSTENFORSCHUNG GMBH;AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS;ALFRED-WEGENER-INSTITUT HELMHOLTZ-ZENTRUM FUR POLAR- UND MEERESFORSCHUNG;IMAR- INSTITUTO DO MAR;THE UNIVERSITY OF RHODE ISLAND;STIFTELSEN NANSEN SENTER FOR MILJOOG FJERNMALING;UNIVERSITY OF BRISTOL;CIIMAR - Centro Interdisciplinar de Investigaç?o Marinha e Ambiental;WAGENINGEN UNIVERSITY;UNIVERSITEIT UTRECHT;HELMHOLTZ ZENTRUM FUR OZEANFORSCHUNG KIEL;FLORIDA ATLANTIC UNIVERSITY BOARD OF TRUSTEES;BANGOR UNIVERSITY;STICHTING NEDERLANDSE WETENSCHAPPELIJK ONDERZOEK INSTITUTEN;UNIVERSITEIT VAN AMSTERDAM";"PT;ES;IT;CA;NL;UK;SE;DE;US;NO";;1;0;0;1;0;0 200599;706349;RGDQG;CLOSED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Renormalisation Group methods for discrete Quantum Gravity;2016-09-01;2018-08-31;;"Understanding quantum gravity requires us to bridge a large gap of scales. The fundamental theory we are searching for is a theory of spacetime at the shortest distances and highest energies. There are many competing proposals for what type of structure best describes this regime. We can not currently generate these high energies in the lab, and hence the most likely method of observing quantum gravity effects are large scale, i.e. astronomical and cosmological observations. To make phenomenological predictions for these large structures, from short scale quantum gravity models, we need to use a renormalisation procedure. In solid state physics, it is common to use real space renormalisation, in which systems at different sizes are directly related. An example of this is block spin renormalisation of the Ising model, by summarising several spins into one block the system is rescaled, leading to an effective description at larger scales. Applying a similar blocking renormalisation to discrete theories of quantum gravity can help us understand their scaling behaviour. This scaling behaviour can then be used to generalise from small scale simulations to larger scale structures, and to identify universal characteristics arising in these models. I have much experience in working with discrete gravity systems, using both analytic and computational methods, which the research and training covered in this proposal will allow me to extend. The host institution, Radboud University in Nijmegen, was chosen for the excellent quality of research. The quantum gravity group led by Professor Loll will provide expert advice, and the strong program of visitors will further enrich the project. The mathematical physics group is comprised of experts in the field of non-commutative geometry, and the proposed research will strengthen the interdisciplinary ties between these groups.";165598,8;165598,8;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;STICHTING KATHOLIEKE UNIVERSITEIT;NL;;;;1;0;0;1;0;0 199381;691246;QUANTUM DYNAMICS;SIGNED;H2020-EU.1.3.3.;MSCA-RISE-2015;H2020;New Geometry of Quantum Dynamics;2016-01-01;2019-12-31;;"The Project aims to make significant advances to the field of noncommutative geometry by developing new methods through substantial interaction within sub-fields of noncommutative geometry and two other areas of pure mathematics. The main focus will be to determine the topological non-triviality of new types of quantum fibrations. Also, we aim to construct quantum metric geometries of crossed products and graph algebras relating the Lipschitz-norm and Dirac-operator approaches. The Project will combine various areas, which although interacting on the fundamental level, have had their concrete and usable connections mostly unexplored. The success of the Project depends on connecting centres of excellence in relevant topics for the exchange of ideas and and production of high-quality collaborative results. The network has been carefully chosen to include the world's leading experts as well as promising early career researchers. Not only does this guarantee the participants access to an enormous knowledge base, it will also ensure that new and innovative lines of research will continue to be developed long after the Project has finished. In particular, the collaborative nature of the project will be of great benefit to the early career researchers involved. In pure mathematics, fields often become so specialised that only a small number of people around the world might be actively researching a particular topic. This can make career progression very difficult. The interdisciplinary nature of the Project will expose the participants to a host of new mathematics and new collaborations. Consequently, this diversification will result in significantly more career opportunities than would otherwise be available.";589500;288000;H2020-MSCA-RISE-2015;/MSCA-RISE;INSTYTUT MATEMATYCZNY POLSKIEJ AKADEMII NAUK;PL;"WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER;THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN;UNIWERSYTET WARSZAWSKI;VRIJE UNIVERSITEIT BRUSSEL;SCUOLA INTERNAZIONALE SUPERIORE DI STUDI AVANZATI DI TRIESTE;KOBENHAVNS UNIVERSITET;UNIWERSYTET LODZKI;UNIVERSITY OF GLASGOW";"DE;UK;PL;BE;IT;DK";;1;0;0;1;0;0 205592;722523;CONTEXT;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2016;H2020;COllaborative Network for Training and EXpertise in psychoTraumatology;2016-09-01;2020-08-31;;"Mental health disorders afflict more than one-third of the EU’s population each year with an annual economic cost to the EU of €432 billion. The ‘COllaborative Network for Training and EXcellence in psychoTraumatology’ (CONTEXT) is an international, interdisciplinary European Industrial Doctorate (EID) designed to address deficiencies in psychotraumatology training and innovation. A key feature of CONTEXT is the minimum 50% secondment of each ESR to the non-academic sector. Consistent with the requirements of an EID, this component grants ESRs access to populations not otherwise accessible in standard doctoral training programmes. This design will facilitate a new cohort of researchers and practitioners who can translate research into practice, thereby mitigating the impact of psychotrauma in the EU. The goal of CONTEXT is to develop a high quality, innovative research training programme to build capacity and expertise, and foster innovative practice and social enterprise in the area of psychotraumatology. The nine beneficiaries of CONTEXT represent a diverse, interconnected, intersectoral consortium, well placed to collaboratively train and supervise the 12 ESRs. Three interconnected research work packages, each targeting a priority population in Europe (EU-based asylum seekers and refugees, WP3; emergency-service personnel and humanitarian first-responders, WP4; and victims and perpetrators of childhood- and gender-based violence, WP5), address current and emergent skill and professional deficiencies that are essential in curbing the adverse social consequences of trauma-related psychological distress within the EU. CONTEXT enjoys significant support and commitment from highly regarded, international stakeholders and influencers at the political, scientific, and professional level.";3316177,44;3316177,44;H2020-MSCA-ITN-2016;/MSCA-ITN-EID;THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN;IE;"PROBATION BOARD OF NORTHERN IRELAND;ODENSE KOMMUNE;SPIRITAN ASYLUM SERVICES INITIATIVE LIMITED;DANSK RODE KORS (DANISH RED CROSS);SYDDANSK UNIVERSITET;Police Service of Northern Ireland;UNIVERSITY OF ULSTER;THE DUBLIN RAPE CRISIS CENTRE LIMITED";"UK;DK;IE";;1;0;0;1;0;0 205529;721995;TRuStEE;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2016;H2020;Training on Remote Sensing for Ecosystem modElling;2016-10-01;2020-09-30;;Understanding and predicting ecosystem functions remains a major challenge in evaluating ecosystem services and biophysical controls on biosphere-atmosphere interactions, as current dynamic vegetation models are still not capable of grasping the spatial and temporal variability in ecosystem processes. Remote sensing (RS) data at a range of scales from proximal observations to global extent sampling can detect essential changes in plant traits (PTs), biodiversity and ecosystem functioning, providing a method for scaling-up. However there are still methodological and technical constraints that hamper a systematic incorporation of RS in ecosystem models, including scalability and multi-source data integration issues. TRuStEE will train a new generation of scientists with complementary and interdisciplinary skills in ecosystem modelling, plant physiology, RS technologies and big data analysis, addressing the specific objectives: 1) to identify essential biodiversity variables (EBVs) and the link with PTs and ecosystem functional properties (EFPs), inferable from RS, 2) to investigate a completely new avenue for assessing vegetation photosynthetic efficiency from RS measurements of canopy fluorescence, 3) to assimilate diverse RS data streams with varying spatial and temporal resolution in dynamic ecosystem models and 4) to exploit new satellite missions (e.g. ESA-FLEX, ESA-Sentinels, NASA-GEDI) and EO products for the upscaling of PTs, EBVs and EFPs. The early stage researchers (ESRs) involved will strongly benefit from the network of internationally recognized scientists and private companies with relevant expertise in these topics. The cooperation program proposed will link academic and non-academic participants to allow the circulation of ESRs giving them the opportunity to become new research and innovation leaders in the most cutting edge sophisticated technologies in the field, increasing their employability in both academic and private sectors.;3062364,12;3062364,12;H2020-MSCA-ITN-2016;/MSCA-ITN-ETN;UNIVERSITA' DEGLI STUDI DI MILANO-BICOCCA;IT;"VLAAMSE INSTELLING VOOR TECHNOLOGISCH ONDERZOEK N.V.;THE UNIVERSITY OF EXETER;FORSCHUNGSZENTRUM JULICH GMBH;UNIVERSITEIT TWENTE;AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS;FONDAZIONE EDMUND MACH;AEROVISION BV;QUESTUAV LTD;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV";"BE;UK;DE;NL;ES;IT";;1;0;0;1;0;0 205447;724084;EAGLE;SIGNED;H2020-EU.3.4.;GV-02-2016;H2020;Efficient Additivated Gasoline Lean Engine;2016-10-01;2020-03-31;;"The decrease of CO2 & particulates emissions is a main challenge of the automotive sector. European OEMs and automotive manufacturers need new long term technologies, still to be implemented by 2030. Currently, hybrid powertrains are considered as the main trend to achieve clean and efficient vehicles. EAGLE project is to improve energy efficiency of road transport vehicles by developing an ultra-lean Spark Ignition gasoline engine, adapted to future electrified powertrains. This new concept using a conventional engine architecture will demonstrate more than 50% peak brake thermal efficiency while reducing particulate and NOx emissions. It will also reach real driving Euro 6 values with no conformity factor. This innovative approach will consequently support the achievement of long term fleet targets of 50 g/km CO2 by providing affordable hybrid solution. EAGLE will tackle several challenges focusing on: • Reducing engine thermal losses through a smart coating approach to lower volumetric specific heat capacity under 1.5 MJ/m3K • Reaching ultra-lean combustion (lambda > 2) with very low particulate (down to 10 nm) emission by innovative hydrogen boosting • Developing breakthrough ignition system for ultra-lean combustion • Investigating a close loop combustion control for extreme lean limit stabilization • Addressing and investigating NOx emissions reduction technologies based on a tailor made NOx storage catalyst and using H2 as a reducing agent for SCR. A strong engine modeling approach will allow to predict thermal and combustion performances to support development and assess engine performances prior to single and multi-cylinder test bench application. An interdisciplinary consortium made of nine partners from four different countries (France, Germany, Italy, Spain) will share its cutting-edge know-how in new combustion process, sensing, control, engine manufacturing, ignition system, simulation & modeling, advanced coating, as well as after-treatment systems.";5993062,74;5993062,74;H2020-GV-2016-INEA;/RIA;IFP Energies nouvelles;FR;"RENAULT SAS;SAINT-GOBAIN CENTRE DE RECHERCHES ET D'ETUDES EUROPEEN;RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN;UNIVERSITA DEGLI STUDI DI NAPOLI FEDERICO II;CONTINENTAL AUTOMOTIVE FRANCE SAS;UNIVERSITAT POLITECNICA DE VALENCIA;CONTINENTAL AUTOMOTIVE GMBH;FEV EUROPE GMBH";"FR;DE;IT;ES";;1;0;0;1;0;0 205451;723791;PENNY;SIGNED;H2020-EU.3.3.1.;EE-08-2016;H2020;Psychological, social and financial barriers to energy efficiency;2016-09-01;2019-08-31;;The project aims at improving our understanding on behavioural mechanisms in energy efficiency, following an interdisciplinary and broad behavioural science approach. The project will provide an empirical and numerical assessment of the psychological, social, economic and financial factors that influence energy efficiency in the residential and industry sectors By paring with energy utilities and retailers in different European countries, the project will conduct scientific experiments (A/B testing) which will enhance the design of policies aiming at maximizing energy efficient behaviors. The project will use novel data from different European countries to take into consideration institutional and political factors. The project will analyze consumers’ behavior related to the consumption of energy, the investment in energy efficient products, as well as the renovation of buildings. Finally, ex ante assessment will be executed using improved energy economy models, which will generate quantitative information with regard to expected impacts of EU and global policies.;1985237,5;1501837,5;H2020-EE-2016-RIA-IA;/RIA;FONDAZIONE ENI ENRICO MATTEI;IT;"WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER;DEBRECENI EGYETEM;EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH;POLITECNICO DI MILANO;RIJKSUNIVERSITEIT GRONINGEN";"DE;HU;CH;IT;NL";;1;0;0;1;0;0 193905;642372;INSPIRATION;SIGNED;H2020-EU.3.5.2.;SC5-10b-2014;H2020;INtegrated Spatial PlannIng, land use and soil management Research ActTION;2015-03-01;2018-02-28;;"The aim of INSPIRATION is to adopt a funder and end-user demand-driven approach to establish and promote the adoption of the knowledge creation, transfer and implementation agenda for land use, land-use changes and soil management in the light of current and future societal challenges. Main objectives are: • Formulate, consult on and revise an end-user oriented strategic research agenda (SRA), • Scope out models of implementing the SRA, • Prepare a network of public and private funding institutions willing to commonly fund the execution of the SRA. INSPIRATION’s mission is to improve the supply and effectiveness of science/knowledge take-up by those who really need it. The proposed methodology is based on a multi-stakeholder, multi-national and interdisciplinary approach that covers the variety of stakeholders (public bodies, business, science, citizens and society) and the variety of relevant. The vehicle to engage with all relevant stakeholders across the Member States is a National Focal Point (NFP) in 16 countries. The NFP’s will organize workshops with national stakeholders of funders, end users and researchers across the various soil and land management disciplines. The results will be taken up, structured along four integrative themes and merging into thematic knowledge needs to satisfy the as yet unmet societal challenges and to ensure that knowledge contributes primarily to enable meeting these challenges. Based on these results a cross country and cross discipline dialogue will subsequently be organized among the relevant user communities, funding bodies and scientific communities in Europe in order to reach a trans-national, prioritized SRA as well as a model for execution of this SRA. Thus to achieve an SRA of which national funders believe that for any Euro they spend, they will get a multitude of Euro’s worth of knowledge in return. Knowledge welcomed to face their national, societal challenges.";2910604,25;2598760,5;H2020-SC5-2014-one-stage;/CSA;UMWELTBUNDESAMT;DE;"SLOVENSKA TECHNICKA UNIVERZITA V BRATISLAVE;DR. FERBER, UWE UND GRAUMANN, DOREEN PROJEKTGRUPPE STADT + ENTWICKLUNG;INSTYTUT EKOLOGII TERENOW UPRZEMYSLOWIONYCH;SITI - ISTITUTO SUPERIORE SUI SISTEMI TERRITORIALI PER L'INNOVAZIONE;SUOMEN YMPARISTOKESKUS;FUNDACION TECNALIA RESEARCH & INNOVATION;MINISTERIE VAN INFRASTRUCTUUR EN WATERSTAAT;HELMHOLTZ-ZENTRUM FUR UMWELTFORSCHUNG GMBH - UFZ;DIU DRESDEN INTERNATIONAL UNIVERSITY GMBH;STADTLAND UG;STATENS GEOTEKNISKA INSTITUT;BUREAU DE RECHERCHES GEOLOGIQUES ET MINIERES;RIJKSINSTITUUT VOOR VOLKSGEZONDHEID EN MILIEU;STICHTING DELTARES;EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH;EIDGENOESSISCHE FORSCHUNGSANSTALT WSL;UNIVERSITAET FUER BODENKULTUR WIEN;INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU PEDOLOGIE, AGROCHIMIE SI PROTECTIA MEDIULUI;UNIVERSIDADE DO ALGARVE;THE UNIVERSITY OF NOTTINGHAM;OPENBARE VLAAMSE AFVALSTOFFENMAATSCHAPPIJ;Institute of Geonics of the AS CR, v.v.i.;FONDAZIONE LINKS - LEADING INNOVATION & KNOWLEDGE FOR SOCIETY;URBANISTICNI INSTITUT REPUBLIKE SLOVENIJE";"SK;DE;PL;IT;FI;ES;NL;SE;FR;CH;AT;RO;PT;UK;BE;CZ;SI";;1;0;0;1;0;0 193909;642420;BiodivERsA3;SIGNED;H2020-EU.3.5.2.;SC5-09-2014;H2020;Consolidating the European Research Area on biodiversity and ecosystem services;2015-02-01;2020-01-31;;"The loss of biodiversity and degradation of ecosystems jeopardize the sustainable provision of ecosystem services and are major scientific and societal challenges. Addressing this challenge and providing scientific support to stakeholders and policy makers requires a coherent interdisciplinary research framework, with coordinated strategies and programmes at the national, regional and international levels, which are the relevant scales for many biodiversity issues. By networking 32 funding agencies from 18 countries, BiodivERsA3 aims to strengthen the ERA on biodiversity. Building on the previous experiences of the projects BiodivERsA1&2 and NetBiome, BiodivERsA3 will promote and support coordinated pan-European research on biodiversity and ecosystem services. It will strengthen research and research programmes coordination with the ultimate aim to provide policy makers and other stakeholders with adequate knowledge, tools and practical solutions to address biodiversity and ecosystem degradation. The objectives are to: - Enhance the capacity of the network to coordinate research programmes on biodiversity and ecosystem services more completely in Europe (including overseas territories) and to increase the international dimension of BiodivERsA activities. - Develop a strategic, multi-annual vision of the network’s priorities, based on ambitious mapping and foresight activities developed in collaboration with key initiatives in the field. - Design and implement a co-funded call and other joint calls to better integrate research on biodiversity and ecosystem services across Europe. - Develop a range of other joint activities, in particular alignment of national research programmes for biodiversity and ecosystem services, and activities for promoting mobility and equal opportunities for researchers and reinforcing data sharing. - Promote effective science-policy and science-society (including science-business) dialogue during the whole research process.";37967427;11988018;H2020-SC5-2014-one-stage;/ERA-NET-Cofund;FONDATION FRANCAISE POUR LA RECHERCHE SUR LA BIODIVERSITE;FR;"NEDERLANDSE ORGANISATIE VOOR WETENSCHAPPELIJK ONDERZOEK;BULGARIAN NATIONAL SCIENCE FUND;VIDEKFEJLESZTESI MINISZTERIUM;FONDS ZUR FÖRDERUNG DER WISSENSCHAFTLICHEN FORSCHUNG;SIHTASUTUS EESTI TEADUSAGENTUUR;GOBIERNO DE CANARIAS;AGENCE DE DEVELOPPEMENT ECONOMIQUE DE LA NOUVELLE CALEDONIE ASSOCIATION;Lietuvos mokslo taryba;Unitatea Executiva pentru Finantarea Invatamantului Superior, a Cercetarii, Dezvoltarii si Inovarii;FUNDO REGIONAL PARA A CIENCIA E TECNOLOGIA;DEUTSCHE FORSCHUNGSGEMEINSCHAFT;THE SECRETARY OF STATE FOR ENVIRONMENT, FOOD AND RURAL AFFAIRS;MINISTERIO DE ECONOMIA, INDUSTRIA Y COMPETITIVIDAD;SUOMEN AKATEMIA;DEUTSCHES ZENTRUM FUER LUFT - UND RAUMFAHRT EV;FORSKNINGSR?DET FÖR MILJÖ, AREELLA NÄRINGAR OCH SAMHÄLLSBYGGANDE;NARODOWE CENTRUM NAUKI;MINISTRY OF AGRICULTURE AND FORESTRY;NORGES FORSKNINGSRAD;NATURVARDSVERKET;REGION GUYANE;MINISTERE DE L'ECOLOGIE DU DEVELOPPEMENT DURABLE DES TRANSPORTS ET DU LOGEMENT;SCHWEIZERISCHER NATIONALFONDS ZUR FORDERUNG DER WISSENSCHAFTLICHEN FORSCHUNG;SERVICE PUBLIC FEDERAL DE PROGRAMMATION POLITIQUE SCIENTIFIQUE;GUADELOUPE REGION;JNCC SUPPORT CO LBG;SLOVENSKA AKADEMIA VIED;AGENCE NATIONALE DE LA RECHERCHE;REGION REUNION;FONDS VOOR WETENSCHAPPELIJK ONDERZOEK-VLAANDEREN;FUNDACAO PARA A CIENCIA E A TECNOLOGIA;NATURAL ENVIRONMENT RESEARCH COUNCIL";"NL;BG;HU;AT;EE;ES;NC;LT;RO;PT;DE;UK;FI;SE;PL;TR;NO;FR;CH;BE;SK";;1;0;0;1;0;0 206149;716908;TopoCold;SIGNED;H2020-EU.1.1.;ERC-2016-STG;H2020;Manipulation of topological phases with cold atoms;2017-02-01;2022-01-31;;"Topological states of matter constitute one of the hottest disciplines in quantum physics, demonstrating a remarkable fusion between elegant mathematical theories and technological applications. However, solid-state experiments only provide a limited set of physical systems and probes that can reveal non-trivial topological order. It is thus appealing to seek for alternative setups exhibiting topological properties. Cold atoms in optical lattices constitute an instructive and complementary toolbox, being extremely versatile, clean and controllable. In fact, cold-atom theorists and experimentalists have recently developed new tools providing the building blocks for the exploitation of topological atomic gases. TopoCold will propose realistic optical-lattice setups hosting novel topologically-ordered phases, based on those technologies that are currently developed in cold-atom experiments. The central goal of the project consists in identifying unambiguous manifestations of topological properties that are specific to the cold-atom framework. We will establish concrete methods to experimentally visualize these signatures, elaborating efficient schemes to detect the unique features of topological phases using available manipulation and imaging techniques. This central part of the TopoCold project will deepen our understanding of topological phenomena and guide ongoing experiments. We also plan to elaborate simple protocols to exploit topological excitations, based on the great controllability of atom-light coupling methods. Moreover, by tailoring the geometry and laser-coupling of optical-lattice setups, we will explore topological systems that are not accessible in solid-state devices. Finally, we will study the properties of topological phases that arise in the strongly-correlated regime of atomic gases. TopoCold will build a bridge between several communities, deepening our knowledge of topological phases from an original and interdisciplinary perspective.";1038039;1038039;ERC-2016-STG;/ERC-STG;UNIVERSITE LIBRE DE BRUXELLES;BE;;;;1;0;0;1;0;0 205589;722287;PAcMEN;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2016;H2020;Predictive and Accelerated Metabolic Engineering Network;2016-10-01;2020-09-30;;"The world economy is dependent on fossil resources: oil, gas and coal. The fossil resources are finite and their consumption causes catastrophic environmental changes. Therefore we need to move towards sustainable economy using renewable resources for energy and chemicals production. Via metabolic engineering approach, novel microbial cells can be created that can convert biomass and waste into fuels and chemicals. Metabolic engineering however distinguishes itself from other engineering disciplines by low predictability of the design and long turnover times for the cell factory construction and screening. Therefore there is a need for scientists, who can address these challenges. European Training Network on Predictable and Accelerated Metabolic Engineering Networks (PAcMEN) will be established at 5 renowned European universities and 2 SMEs with participation of 5 industrial and 1 academic partner organizations. In this program 16 PhD students (of which 15 funded by EU contribution) will learn to conduct state-of-the-art research on metabolic engineering of microbial cell factories and learn to commercialize innovations. This will be achieved via collaborative research projects under supervision of top scientists from academia and industry, network training, secondments with network partners, training on innovation and entrepreneurship, and individual career coaching. Altogether, PAcMEN training programme will provide young scientists with the ideal combination of scientific, technological, industrial and management skills to prepare them for their role as breakthrough pioneers in the establishment of tomorrow’s biorefineries. The PAcMEN project will have an overall positive impact by strengthening the research networks in the area of metabolic engineering, establishing long-term collaborations between the universities and industry, and by creating a framework for future interdisciplinary training programs.";3994075,8;3994075,8;H2020-MSCA-ITN-2016;/MSCA-ITN-ETN;DANMARKS TEKNISKE UNIVERSITET;DK;"RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN;ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE;SILICOLIFE LDA;SESAM-BIOTECH GMBH;TECHNISCHE UNIVERSITEIT DELFT;CHALMERS TEKNISKA HOEGSKOLA AB";"DE;CH;PT;NL;SE";;1;0;0;1;0;0 205581;721537;ImageInLife;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2016;H2020;Training European Experts in Multilevel Bioimaging, Analysis and Modelling of Vertebrate Development and Disease;2017-01-01;2020-12-31;;"This proposal sprang from European scientists in both academia and industry who identified a common challenge: setting up a training frame to educate the next generation of imagers in complex biological systems (healthy & pathological), so they are able to master all major aspects of this competitive field and bring important innovations to universities and companies. The long-term goal of any initiative to image biological processes is reaching cellular or subcellular resolution in a complete organism. This is now possible using vertebrate embryos as models and the most recent technological advances as tools. ESRs will be trained by addressing the following scientific bottlenecks and challenges: -Preparing vertebrate embryos (rodent & zebrafish) for optimal imaging -Fine-tuning sensors, reporters and actuators to track cell types, cellular processes and behaviours in living organisms -Developing and implementing new imaging instruments -Analysing complex sets of big-data images to extract relevant information -Using processed images to design computational and mathematical models of development and pathologies -Comparing these models with experimental data and create a feedback loop improving the whole work chain from sample preparation to instrumentation and analysis. This interdisciplinary training is based on an intersectoral organisation of the consortium with partners from academia and companies that need these future experts to develop new instruments, screen drugs and chemicals in living systems and develop software to analyse and model medical images. The full training programme is based on an optimal balance between training through research and many network-wide training events, including conferences with physical presence, digital conferences and monthly videolink events. Consortium members are keen to implement both classical and original outreach activities (eg MOOCs, serious games, Lego designs) to bring state-of-the-art microscopy to the classroom.";3562028,64;3562028,64;H2020-MSCA-ITN-2016;/MSCA-ITN-ETN;UNIVERSITE DE MONTPELLIER;FR;"SLOVENSKA TECHNICKA UNIVERZITA V BRATISLAVE;TATRAMED SOFTWARE SRO;UNIVERSITEIT LEIDEN;THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;DITABIS DIGITAL BIOMEDICAL IMAGING SYSTEMS AG;FUNDACIO INSTITUT DE CIENCIES FOTONIQUES;THE MANCHESTER METROPOLITAN UNIVERSITY;INSTITUT PASTEUR;PHASEVIEW;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;ACQUIFER AG";"SK;NL;UK;DE;ES;FR";;1;0;0;1;0;0 205571;722581;PLATO;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2016;H2020;The Post-crisis Legitimacy of the European UnionEuropean Training Network;2017-01-01;2020-12-31;;Is there a crisis in the legitimacy of the European Union? That research question is timely and important. Investigating it is also an ideal way of training research leaders of tomorrow to rethink our assumptions about the study of legitimate political order. Whilst, however, the financial crisis has raised new questions about the legitimacy of the EU, existing theories of legitimacy crises are largely based on single-state political systems. New theory is, therefore, needed to understand what would count as legitimacy crises in the case of a non-state political system such as the EU. PLATO’s (The Post-Crisis Legitimacy of the EU) ESRs will work together as a team to build new theory from 15 investigations into different standards and actors with whom the EU may need to be legitimate. ESRs will go well beyond the state-of-the-art by building a theory of legitimacy crisis in the EU from a uniquely interdisciplinary understanding of how democracy, power, law, economies and societies all fit together with institutions within and beyond the state to affect the legitimacy of contemporary political order. By developing the analytical tools needed to understand a core predicament in which the EU may both need to develop legitimate forms of political power beyond the state and find those forms of power hard to achieve, PLATO will train ESRs with the conceptual clarity needed to define new research questions at the very frontiers of their disciplines and the methodological skills needed to research those questions. They will also be prepared for careers in the non-academic sector (policy-advice, consulting, civil society, European institutions and expert bodies). PLATO’s ambitious cross-university, cross-country and cross-sectoral programme of research training, supervision and secondments will pool resources from a unique network of 9 research-intensive universities and 11 non-academic partners who are themselves key users of state-of-the-art social science research.;3873718,8;3873718,8;H2020-MSCA-ITN-2016;/MSCA-ITN-ETN;UNIVERSITETET I OSLO;NO;"INSTITUT FUER HOEHERE STUDIEN - INSTITUTE FOR ADVANCED STUDIES;UNIVERSITEIT ANTWERPEN;THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;UNIVERSITEIT TWENTE;FONDATION NATIONALE DES SCIENCES POLITIQUES;INSTITUTE OF SOCIOLOGY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC PUBLIC RESEARCH INSTITUTION;FREIE UNIVERSITAET BERLIN;UNIWERSYTET JAGIELLONSKI";"AT;BE;UK;NL;FR;CZ;DE;PL";;1;0;0;1;0;0 205562;721223;CATMEC;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2016;H2020;Catalytic Methods for Sustainable Synthesis. A Merged Experimental and Computational Approach;2017-01-01;2020-12-31;;"CATMEC is a multi-partner European Joint Doctorate (EJD) Programme offering research training in state-of-the-art sustainable chemical synthesis, catalysis, computational chemistry and bioactive molecule design on both traditional and non-traditional (eg flow) platforms. This Doctoral Training Programme integrates complementary, interdisciplinary and intersectoral training and together with enhanced European mobility through planned secondments of researchers, will contribute to EU policy objectives in scientific training and degree assessment. The researchers will be supervised and mentored by internationally recognised experts and have access to state-of-the-art equipment. Hands-on training will be supplemented by formal training courses in relevant and related fields, and a wide variety of complementary training courses, workshops and seminars. The training of researchers will benefit from secondments to industrial partners, gaining exposure to commercial and complementary environments. Overall, it is anticipated that the CATMEC project will provide Early Stage Researchers (ESRs) with an outstanding training experience, through extensive technical and complementary skills development.";1569640,32;1569640,32;H2020-MSCA-ITN-2016;/MSCA-ITN-EJD;THE UNIVERSITY OF SHEFFIELD;UK;"UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA;STOCKHOLMS UNIVERSITET";"ES;SE";;1;0;0;1;0;0 205405;721290;COSMIC;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2016;H2020;European Training Network for Continuous Sonication and Microwave Reactors;2016-10-01;2020-09-30;;The European chemical industry faces some very serious challenges if it is to retain its competitive position in the global economy. The new industries setting up in Asia and the Near East are based on novel process-intensification concepts, leaving Europe desperately searching for a competitive edge. The transition from batch to continuous micro- and milliflow processing is essential to ensure a future for the European fine-chemicals and pharmaceuticals industries. However, despite the huge interest shown by both academia and industrial R&D, many challenges remain, such as the problems of reaction activation, channel clogging due to solids formation and the scaling up of these technologies to match the required throughput. COSMIC, the European Training Network for Continuous Sonication and Microwave Reactors, takes on these challenges by developing material- and energy-efficient continuous chemical processes for the synthesis of organic molecules and nanoparticles. The intersectoral and interdisciplinary COSMIC training network consists of leading universities and industry participants and trains 15 ESRs in the areas of flow technology, millifluidics and external energy fields (ultrasound and microwaves). These energy fields can be applied in structured, continuous milli-reactors for producing high-value-added chemicals with excellent yield efficiencies – in terms of throughput, waste minimization and product quality – that simply cannot be achieved with traditional batch-type chemical reactors. The chemical processes that are at the heart of COSMIC’s game-changing research are catalytic reactions and solids-forming reactions. COSMIC’s success, which is based on integrating chemistry, physics and process technology, will re-establish European leadership in this crucial field and provide it with highly trained young experts ready for dynamic careers in the European chemical industry.;3833301,24;3833301,24;H2020-MSCA-ITN-2016;/MSCA-ITN-ETN;KATHOLIEKE UNIVERSITEIT LEUVEN;BE;"MICROINNOVA ENGINEERING GMBH;UNIVERSIDAD DE ZARAGOZA;GEORG-AUGUST-UNIVERSITAT GOTTINGENSTIFTUNG OFFENTLICHEN RECHTS;UNIVERSITA DEGLI STUDI DI TORINO;UNIVERSIDAD DE CORDOBA;ARKEMA FRANCE SA;UNIVERSITY COLLEGE LONDON";"AT;ES;DE;IT;FR;UK";;1;0;0;1;0;0 205524;722012;CATCH;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2016;H2020;Cancer: Activating Technology for Connected Health;2016-09-01;2020-08-31;;"Advances in cancer diagnosis and treatment have been groundbreaking, and we are now considering some cancers as chronic disease rather than fatal illness. This moves the point of focus in the fight against cancer from sustaining life towards maximizing functional capacity and quality of life (QOL). A critical element in this shift has been the rise of active rehabilitation in the management of cancer. In the past 10-15 years we have seen the emergence of significant evidence for the clinical effectiveness of active rehabilitation in cancer care, both in maximizing functional capacity and QOL, and preventing secondary recurrence. However, many barriers to implementation of active rehabilitation in cancer care exist due to its profound physical and psychological implications. Technology advances such as gamification based on biofeedback, and neuromuscular electrical stimulation, can help address some of these barriers but much must be done before we can effectively marry the technological capability to the unmet clinical need. In particular we need to understand specific challenges and patient journeys associated with cancer care and how we can help patients to leverage psychological tools to better engage in their own care. We then need to optimize technological tools to meet patients’ rehabilitation needs, and finally, to understand how to bring resultant solutions to market where they can have maximal impact on quality of care. This can only be done by a multidisciplinary programme of research involving close collaboration between researchers in academic, clinical and industry settings. CATCH is a deep collaboration across academic, business and clinical sectors. Students will benefit from intersectoral secondments, interdisciplinary communication skills, public engagement and outreach while working on a programme of interrelated core research projects addressing gaps in the knowledge and evidence base for technology enabled cancer rehabilitation mentioned above.";2120806,44;2120806,44;H2020-MSCA-ITN-2016;/MSCA-ITN-EID;UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN;IE;"BEACON HOSPITAL SANDYFORD LIMITED;VALERO Y ARBIZU SOCIEDAD LIMITADA;SYDDANSK UNIVERSITET;UNIVERSIDAD DE LA IGLESIA DE DEUSTO ENTIDAD RELIGIOSA;SALUMEDIA TECNOLOGIAS SL";"IE;ES;DK";;1;0;0;1;0;0 205551;722456;CORE;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2016;H2020;Continuous Resolution and Deracemization of Chiral Compounds by Crystallization;2016-10-01;2020-09-30;;"Industries are in need of highly skilled academically trained experts and powerful sets of tools enabling the design, control & prediction of optimized & efficient production process of future high-value products such as chiral pharmaceuticals. The CORE Network will in parallel train 15 ESRs and develop tools, approaches and methods within the area of Continuous Resolution (CORE), the process to obtain enantiopure molecules of chiral compounds. The training objective of the CORE network is to deliver a CORE skills toolbox of knowledge, personal, organizational and impact skills to a core of multi-disciplinary scientists and engineers in the interdisciplinary and cross-sectional field of Continuous Resolution. Each ESR obtains dedicated training through their research project, network events, a webinar course, management involvement and an academic & industrial secondment. The research objective of the CORE Network is to jointly construct a CORE Industrial Toolbox on Continuous Resolution that provides next generation tools, approaches and methods to industry for the development continuous resolution processes. The strongly involved industrial partners will ensure that the CORE Industrial Toolbox fulfils their requirements in the skills gap areas Towards Continuous, Hybrid Resolution and Enabling Resolution. CORE brings together 8 academic and 7 industrial partners resulting in an unparalleled combination of chirality, synthesis and crystallization training and research covering the areas of Chemical Engineering, Chemistry and Applied Physics.";3926004,12;3926004,12;H2020-MSCA-ITN-2016;/MSCA-ITN-ETN;UNIVERSITY OF STRATHCLYDE;UK;"FRIEDRICH-ALEXANDER-UNIVERSITAET ERLANGEN NUERNBERG;THE UNIVERSITY OF MANCHESTER;UNIVERSITE DE ROUEN NORMANDIE;OTTO-VON-GUERICKE-UNIVERSITAET MAGDEBURG;STICHTING KATHOLIEKE UNIVERSITEIT;SYNCOM BV;EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH";"DE;UK;FR;NL;CH";;1;0;0;1;0;0 205513;721766;FBI;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2016;H2020;Multimodal, Functional Bio-Photonic Imaging;2016-10-01;2020-09-30;;"FBI fosters education of ESRs on an emerging, multimodal imaging platform and its translation into clinical and biological applications. In FBI, 15 ESRs are trained at world-leading European academic institutions and companies, thus forming strong interdisciplinary relations between industry, technical sciences and clinical end-users. Optical imaging has huge potential to address unmet clinical needs by combining non-invasive and real-time capture of biomedical information; thus enabling earlier onset of treatment, reduced therapy costs, reduced recurrence rates, and improved clinical outcomes. Up to now, optical modalities were applied as standalone techniques each targeting one biomarker. Recently it has been shown that diagnosis is significantly improved by combining different contrast mechanisms simultaneously in a multimodal approach, i.e., staging and grading of lesions is feasible. FBI proposes to combine a selection of modalities depending on the targeted disease. Suspicious lesions are analysed with optical coherence tomography, optoacoustic tomography, multi-photon tomography, and Raman spectroscopy to provide morphological, label-free microangiography, and intrinsic biochemical information, respectively. An important issue is the need for endoscopy: combining said modalities into endoscopes is challenging due to the integration of different imaging concepts, scanning and detection methods, and laser sources. Accordingly, there is a huge need for effectively translating these technical solutions to industry and clinics, which traditionally is restricted by lack of understanding of applications or limited knowledge of new technology. All these barriers are addressed by FBI through research and development of novel photonic components and systems, through educating ESRs in understanding clinical, biological and commercial challenges, and through developing tailored technical solutions and efficient translation of technology within a strong network.";3902716,44;3902716,44;H2020-MSCA-ITN-2016;/MSCA-ITN-ETN;DANMARKS TEKNISKE UNIVERSITET;DK;"MEDIZINISCHE UNIVERSITAET WIEN;EKSPLA UAB;TECHNISCHE UNIVERSITAET MUENCHEN;NKT PHOTONICS A/S;ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE;PHILIPS ELECTRONICS NEDERLAND B.V.;TECHNISCHE UNIVERSITEIT EINDHOVEN;FEMTOLASERS PRODUKTIONS GMBH;ITHERA MEDICAL GMBH";"AT;LT;DE;DK;CH;NL";;1;0;0;1;0;0 204484;694033;STEM-BCPC;SIGNED;H2020-EU.1.1.;ERC-ADG-2015;H2020;Signal Transduction and Epigenetic Mechanisms of Breast Cell Plasticity and Cancer;2016-10-01;2021-09-30;;"Breast cancer is diagnosed in ~1.4 million women worldwide and ~500,000 lives are lost to the disease annually. Patients may do well after surgery and initial treatment, but drug resistant and fatal metastases often develop. Improved treatment options are urgently needed. The connecting thread of this project is the identification of epigenetic drivers of breast cell fate, tumor heterogeneity and metastasis. Tumor heterogeneity impinges on prognosis, response to therapy, and metastasis and is one of the most important and clinically relevant areas of cancer research. Tumor heterogeneity results from genetic and epigenetic alterations that enhance the plasticity and fitness of cancer cells in the face of hurdles like the metastatic cascade and anti-cancer therapies. Unfortunately, the driving molecular mechanisms remain unclear, particularly the potential interplay between signalling pathways and epigenetic programs. This interdisciplinary project uses pathophysiologically relevant models and state-of-the-art technologies to identify molecular mechanisms underlying crosstalk between key signalling pathways and epigenetic programs in the normal and neoplastic breast. We hypothesize that interfering with these programs will decrease tumor heterogeneity. We will address the effects of: - SHP2/ERK signalling on the epigenetic programs of tumor-initiating cells (Aim 1) - PI3K pathway hyperactivation on the epigenetic programs underpinning cell plasticity (Aim 2) - Epigenetic regulators on normal mammary cell self-renewal and on metastasis (Aim 3) By investigating the integrated effects of key signalling pathways and epigenetic programs in normal and neoplastic breast, this multipronged project will identify and validate mechanisms of cell plasticity. The derived mechanistic understanding will generate means to interfere with tumor heterogeneity and thus improve the efficacy of anti-cancer therapies and ultimately the clinical outcome for patients with breast cancer.";2499250;2499250;ERC-2015-AdG;/ERC-ADG;UNIVERSITAT BASEL;CH;FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH;CH;;1;0;0;1;0;0 204518;702911;BioMIC-FUEL;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-GF;H2020;Bio-inspired photonics for enhanced microalgal photosynthesis in biofuels;2017-01-01;2019-12-31;;Algal biofuels have the potential to provide a sustainable carbon-neutral source to fossil fuels, however the scaling up of algal systems is economically challenging. Here we propose a bio inspired approach to exploiting light-matter interaction by understanding and mimicking the optical properties of corals. We aim to inspire the development of improved photonic materials that can be used to maximise algal growth in order to radically transform the algal biofuel sector. The specific objectives are to 1) explore the in vivo light field, optical properties and photosynthetic efficiency of a range of coral species from different light regimes, 2) understand the nanophotonic and structural properties of corals underlying the optimised light modulation and 3) apply the biophotonic insight to design novel photonic materials for the improved growth of microalgae. The proposal is highly interdisciplinary involving optical and photonic characterisation, photosynthesis research and the fabrication of novel materials. The successful implementation of this project will have a high societal impact, through improving the biofuel sector and working towards carbon-neutral fuel sources.;251857,8;251857,8;H2020-MSCA-IF-2015;/MSCA-IF-GF;THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;UK;;;;1;0;0;1;0;0 204790;692876;NaTuRe;SIGNED;H2020-EU.1.1.;ERC-ADG-2015;H2020;Nanotube Mechanical Resonator, Spin, and Superfluidity;2017-01-01;2021-12-31;;"Mechanical resonators based on carbon nanotubes are truly exceptional sensors of mass and force. In the last years, my group revealed these outstanding figures of merit of nanotube resonators. Here, the project NaTuRe will take advantage of these sensing capabilities to study physical phenomena in fascinating regimes that have not been explored thus far. Specifically, I will address three directions with major scientific interests: 1- I propose to perform electron spin resonance (ESR) measurements on single molecules using nanotube resonators. The goal is to see whether nature can provide molecular electronic spins endowed with long dephasing time. For this, we will measure molecular spins in a regime where the magnetic noise of the environment is reduced to an unprecedented level. In case of success, this work could open avenues in quantum science by allowing experiments not possible with the electronic spins of nitrogen-vacancy centres in diamond. 2- My team will carry out nuclear magnetic resonance (NMR) measurements on single nuclear spins. We will also perform magnetic-resonance force microscopy in order to image these individual nuclear spins. Achieving the objectives proposed here will be an unprecedented success in magnetic resonance imaging (MRI). 3- NaTuRe proposes a completely new experimental approach to investigate superfluidity. We will use a nanotube mechanical resonator to probe the superfluidity properties of helium-4 layers adsorbed onto the suspended nanotube. Our experimental approach will allow us to study various quantum phenomena in superfluidity of considerable interest and from a radically new perspective. NaTuRe is a highly-interdisciplinary project with possible implications in quantum science, opto-mechanics, nano-science, structural biology, and low-temperature physics.";2503459;2503459;ERC-2015-AdG;/ERC-ADG;FUNDACIO INSTITUT DE CIENCIES FOTONIQUES;ES;;;;1;0;0;1;0;0 201329;705444;MOPTOPus;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-GF;H2020;Metal oxide nanocrystals as optically driven dynamic manipulators of local (opto)electronic properties;2016-10-01;2019-09-30;;"Contactless manipulation of nanomaterials to map critical properties at their native length scale is of major importance for the study of the local structure-properties relationship. To this aim we will implement plasmonic degenerately doped metal oxide nanocrystals (MO NCs) with carrier densities around 10^21 cm^-3 and localized surface plasmon resonances (LSPRs) in the near infrared (NIR) as optically driven contactless nanostructures to dynamically manipulate local optoelectronic properties. Capacitive charging upon photo-doping enables the optical regulation of their carrier density, leading to contactless nano-gates for the nanometer scale manipulation of local potentials. Intentional charge release upon plasmon induced ‘hot’ electron extraction through excitation of the LSPR facilitates local charge transfer, resulting in a light driven nano-manipulator converting local light energy into electrical energy based entirely on optical triggers. Appropriately designed MO core-shell NCs will be prepared to establish photo-doping, charge storage and ‘hot’ electron extraction, and to extract critical physical and chemical parameters. The nano-devices will be employed to actively manipulate and elucidate the local optoelectronic properties of layered two dimensional materials which are extremely susceptible to local electrostatic field and potential changes. Hybrid structure formation is accomplished by depositing the MO nano-devices on top of the nanostructure, while nanoscale manipulation of the local potential and/or localized charge transfer is triggered by light pulses, leading to a contactless nano-device for local optoelectronic manipulation. The successful participation in the MCIF will enhance the innovative potential of the fellow diversifying her individual competences, allowing her to acquire new knowledge and open career possibilities by establishing a new research vision with high potential for applications in interdisciplinary fields.";262269;262269;H2020-MSCA-IF-2015;/MSCA-IF-GF;FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA;IT;;;;1;0;0;1;0;0 201279;704998;QuP;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Long Range Surface Plasmon Polaritons as an Alternative Information Carrier for Nanoscale Quantum Circuitry;2016-03-01;2018-12-29;;"The aim of this innovative and high-impact interdisciplinary proposal is to investigate the potential properties and applications of plasmonic metallic nanostructures that enable the confinement of light to scales beyond the diffraction limit, known as quantum plasmonics. Latest studies have revealed the quantization of surface plasmon polaritons (SPPs). It could be the stepping stone for the generation of miniaturized photonic components for the quantum control of light. This implies that the SPPs would represent a totally new sort of information carrier for nanoscale circuitry, enabling a revolutionary bridge between current diffraction-limited microphotonics and bandwith-limited nanoelectronics, paving the way for integrated quantum information processing. Thus, in a first stage we will develop integrated nanoscale quantum plasmonics building blocks on-a-chip, such as efficient single-photon sources or transistors, which is the component required for the fabrication of true nanoscale quantum computing logic gates. We also plan to exploit the low-Ohmic-losses and prospects for large scale production of ultra-compact cutting-edge graphene plasmonic circuits. This research will be lastly applied to single molecule sensing. Experiments will be performed using innovative techniques for nanofabrication of photonic nanostructures and for characterization. The expected results will allow taking advantage of quantum interference effects, setting up the optical response of the extremely low losses Long Range (LR) SPPs modes within a quantum framework and showing that graphene layers produce strong light-matter interaction and extreme optical field confinement. The results will be compared with ab initio simulations, giving a precise and consistent experimental and theoretical panorama of quantum plasmonics.";170121,6;170121,6;H2020-MSCA-IF-2015;/MSCA-IF-EF-CAR;UNIVERSITAT DE VALENCIA;ES;;;;1;0;0;1;0;0 201212;704120;MIRNANO;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-GF;H2020;Multifunctional miRNA-targeting nanodevices for pluripotent cancer theranostics;2017-01-15;2020-01-14;;"WHAT: MIRNANO project is an interdisciplinary nanotechnology-driven program in which the fields of nanomaterial and DNA functional engineering are merged to develop innovative nanodevices for pluripotent targeted cancer treatment. The leading idea is to focus on aberrantly expressed microRNAs (miRNAs) as targets of the proposed therapeutic care, which allows for tailoring of the action to the genetic expression of a specific tumor. WHY: Current chemotherapy still relies on an untargeted paradigm, which suffers from poisoning side effects and lacks a focused action over the tumor area. Molecular biology has definitely demonstrated the pivotal role played by microRNAs in cancer development and metastasis progression, therefore anti-miR therapy is the ultimate strategy to bet on. Working at the nanoscale will allow to achieve advanced nanomaterials that can home to the specific tumor tissue and silence the aberrantly expressed miRNAs producing a downstream therapeutic effect. HOW: The proposed program is a very challenging project that aims to provide a groundbreaking contribution to cancer treatment. Nanomaterial science is primarily involved in this project. Porous silicon nanoparticles are intended to be used as luminescent, biodegradable, and biocompatible platforms for producing the anti-miR nanodevices. Functionalization with tumor-penetrating peptides will allow to achieve homing of the particles to the site of action, thus specifically targeting the tumor environment. Anti-miR nucleic acids, carried and delivered through the silicon nanocarriers, will ensure knockdown of target miRNAs, inducing downstream suppression of tumor growth. A complementary engineering of the anti-miR nucleic acid unit through rational design of advanced switching structures will allow for developing programmed miR-responsive tools, which are meant to reinforce the primary anti-miR effect with an extra-therapeutic action.";244269;244269;H2020-MSCA-IF-2015;/MSCA-IF-GF;UNIVERSITA DEGLI STUDI DI ROMA TOR VERGATA;IT;;;;1;0;0;1;0;0 201430;706428;Ko-Tsah-To;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Temperatures, ash and soil hydrology: predicting fire impact from plant traits;2016-09-01;2018-08-31;;Climate change increases the frequency and intensity of vegetation fires around the world. Fire can considerably increase the landscape’s vulnerability to flooding and erosion, which is in part caused by fire-induced soil damage and hydrological changes. While it is known that plants can alter the fire environment, there is a major knowledge gap regarding the fundamental mechanisms by which vegetation mediates fire impact on soil physics and hydrology. I will address this gap by considering for the first time the cascading effects of plants on fire and soil hydrology, focusing on two important factors in post-fire hydrology: soil heating and ash. My hypothesis is that plant structural and chemical traits vary within the landscape and control fire impact on soil physical properties by affecting heat and ash production. I will test this hypothesis with a combination of spatial sampling, lab experiments and modeling, using contrasting plant species and soils from watersheds in Portugal and the USA. Multiple regression and principal component analysis will be used to relate fire impacts to the various plant traits. This project can help predict and mitigate fire risk and impact across landscapes, facilitate development of risk maps, and generate knowledge with implications for nature conservation, land use planning, fire management and potential policy making. Aside from helping safeguard soil and (drinking) water resources, the project can also change a European braindrain into a braingain, supporting reintegration of a successful interdisciplinary scientist and her large network after three years in the USA. Additional benefits for Europe include transfer of knowledge gained in the USA and knowledge exchange from southern to northern member states. Through training and research, this project will enhance my success of getting a permanent position in academia and create new opportunities to incorporate hydrology and scale in above-belowground interaction research.;177598,8;177598,8;H2020-MSCA-IF-2015;/MSCA-IF-EF-RI;WAGENINGEN UNIVERSITY;NL;;;;1;0;0;1;0;0 200732;679127;ProFoundNet;SIGNED;H2020-EU.1.1.;ERC-StG-2015;H2020;Probabilistic Foundations for Networks;2016-04-01;2021-03-31;;"In an ever-connected world, increasingly complex network systems play a crucial role in many daily tasks. This results in an acute need for methods/tools that can enable easy control of the network and, at the same time, provide rigorous guarantees about its behavior, performance, and security. Recent years saw the growth of a new software ecosystem -Software-defined networking (SDN)- which advocates a clean and open interface between networking devices and the software that controls them. Yet, existing SDN languages do not support reasoning about crucial quantitative aspects, such as: ``How much congestion is there?' or ``Is the network resilient under failure?'. Enabling compositional quantitative reasoning is the major breakthrough needed to fully realize the vision of SDN. The central objective of this project is to develop new abstractions for programming of networks, with high-level modular constructs. We will provide rigorous semantic probabilistic foundations, enabling quantitative reasoning. This will serve as a solid platform for program analysis tools where compositional reasoning about complex interactions will be a reality. Our goal will be achieved through an interdisciplinary research effort: using techniques from concurrency and formal methods, areas where akin challenges can be found in the quest to design correct software systems. We will leverage the wealth of recent advances in those areas (some of which from the PI's own research) to networks, and bring awareness and new challenges arising from applications in networking to the other two communities. The project will significantly advance the foundations of network programming/verification in new and previously unexplored directions. This line of research will not only result in fundamental theoretical contributions and insights in their own right but will also impact the practice of network programming and lead to new and more powerful techniques for the use of engineers and programmers.";1500000;1500000;ERC-2015-STG;/ERC-STG;UNIVERSITY COLLEGE LONDON;UK;;;;1;0;0;1;0;0 200709;678017;MultiMT;SIGNED;H2020-EU.1.1.;ERC-StG-2015;H2020;Multi-modal Context Modelling for Machine Translation;2016-07-01;2021-06-30;;"Automatically translating human language has been a long sought-after goal in the field of Natural Language Processing (NLP). Machine Translation (MT) can significantly lower communication barriers, with enormous potential for positive social and economic impact. The dominant paradigm is Statistical Machine Translation (SMT), which learns to translate from human-translated examples. Human translators have access to a number of contextual cues beyond the actual segment to translate when performing translation, for example images associated with the text and related documents. SMT systems, however, completely disregard any form of non-textual context and make little or no reference to wider surrounding textual content. This results in translations that miss relevant information or convey incorrect meaning. Such issues drastically affect reading comprehension and may make translations useless. This is especially critical for user-generated content such as social media posts -- which are often short and contain non-standard language -- but applies to a wide range of text types. The novel and ambitious idea in this proposal is to devise methods and algorithms to exploit global multi-modal information for context modelling in SMT. This will require a significantly disruptive approach with new ways to acquire multilingual multi-modal representations, and new machine learning and inference algorithms that can process rich context models. The focus will be on three context types: global textual content from the document and related texts, visual cues from images and metadata including topic, date, author, source. As test beds, two challenging user-generated datasets will be used: Twitter posts and product reviews. This highly interdisciplinary research proposal draws expertise from NLP, Computer Vision and Machine Learning and claims that appropriate modelling of multi-modal context is key to achieve a new breakthrough in SMT, regardless of language pair and text type.";1493771;1493771;ERC-2015-STG;/ERC-STG;IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE;UK;THE UNIVERSITY OF SHEFFIELD;UK;;1;0;0;1;0;0 200485;680358;BIGCODE;SIGNED;H2020-EU.1.1.;ERC-StG-2015;H2020;Learning from Big Code: Probabilistic Models, Analysis and Synthesis;2016-04-01;2021-03-31;;"The goal of this proposal is to fundamentally change the way we build and reason about software. We aim to develop new kinds of statistical programming systems that provide probabilistically likely solutions to tasks that are difficult or impossible to solve with traditional approaches. These statistical programming systems will be based on probabilistic models of massive codebases (also known as ``Big Code') built via a combination of advanced programming languages and powerful machine learning and natural language processing techniques. To solve a particular challenge, a statistical programming system will query a probabilistic model, compute the most likely predictions, and present those to the developer. Based on probabilistic models of ``Big Code', we propose to investigate new statistical techniques in the context of three fundamental research directions: i) statistical program synthesis where we develop techniques that automatically synthesize and predict new programs, ii) statistical prediction of program properties where we develop new techniques that can predict important facts (e.g., types) about programs, and iii) statistical translation of programs where we investigate new techniques for statistical translation of programs (e.g., from one programming language to another, or to a natural language). We believe the research direction outlined in this interdisciplinary proposal opens a new and exciting area of computer science. This area will combine sophisticated statistical learning and advanced programming language techniques for building the next-generation statistical programming systems. We expect the results of this proposal to have an immediate impact upon millions of developers worldwide, triggering a paradigm shift in the way tomorrow's software is built, as well as a long-lasting impact on scientific fields such as machine learning, natural language processing, programming languages and software engineering.";1500000;1500000;ERC-2015-STG;/ERC-STG;EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH;CH;;;;1;0;0;1;0;0 202538;675683;CELTA;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2015-ETN;H2020;Convergence of Electronics and Photonics Technologies for Enabling Terahertz Applications;2016-03-01;2020-02-29;;CELTA: Convergence of Electronics and Photonics Technologies for Enabling Terahertz Applications aims to produce the next generation of researchers who will enable Europe to take a leading role in the multidisciplinary area of utilizing Terahertz technology for applications involving components and complete systems for sensing, instrumentation, imaging, spectroscopy, and communications. All these technologies are key to tackle important solutions in a large number of focus areas relevant for the societal challenges identified in the Horizon2020 work programme. To achieve this objective, CELTA is comprised of eleven leading research institutions and assembled a comprehensive research training programme for all the fifteen early stage researchers (ESRs). CELTA integrates multidisciplinary scientific expertise, complementary skills, and experience working in academia and industry to empower ESRs to work in interdisciplinary teams, integrate their activities, share expertise, and promote a vision of a converged co-design and common engineering language between electronics and photonics for Terahertz technologies. Therefore, CELTA will introduce the strategy of converged electronics and photonics co-design in its research program and makes a special effort on establishing a common engineering language in its training program across the electronics, photonics and applications disciplines. We believe this common engineering language and converged co-design is mandatory to make the next logical step towards efficient and innovation solutions that can reach the market. The detailed compendium of lectures on state-of-the art technology, soft skills and entrepreneurship is accompanied by a research programme that focuses on THz key technologies. CELTA ESRs will develop three demonstrators: beam steering technology for communication applications, a photonic vector analyser for spectroscopy and materials characterization, and a THz imager for sensing applications.;3785419,68;3785419,68;H2020-MSCA-ITN-2015;/MSCA-ITN-ETN;TECHNISCHE UNIVERSITEIT EINDHOVEN;NL;"UNIVERSITA DEGLI STUDI DI ROMA TOR VERGATA;UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN;KUNGLIGA TEKNISKA HOEGSKOLAN;AALTO KORKEAKOULUSAATIO SR;VYSOKE UCENI TECHNICKE V BRNE;UNIVERSITA DEGLI STUDI DELL'AQUILA;POLITECHNIKA WARSZAWSKA;CESKE VYSOKE UCENI TECHNICKE V PRAZE;JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN;DANMARKS TEKNISKE UNIVERSITET;TECHNISCHE UNIVERSITAT DARMSTADT;UNIVERSIDAD CARLOS III DE MADRID";"IT;IE;SE;FI;CZ;PL;DE;DK;ES";;1;0;0;1;0;0 205359;707485;LandGrab;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-GF;H2020;Processes of indigenous community resistance to large extractive projects and their struggles for autonomy in Chile and Peru;2016-11-01;2020-09-24;;"The aim of this Fellowship is for the researcher, Dr Rajiv Maher, to develop his professional capacity, advanced training, interdisciplinary skills, high-impact dissemination, and practical experience in line with the criteria for a leading independent researcher in the EU. This proposal aims to investigate the processes of indigenous community resistance to large natural resource extraction projects and their struggles for autonomy in Chile and Peru. The proposal will also examine the strategies used by companies and governments to gain community acceptance such as those relating to Corporate Social Responsibility (CSR). The researcher expects to achieve these aims during the outgoing phase of the Fellowship where he will access expertise, advanced training and mentoring in Development and Political Ecology. Moreover, the researcher will conduct ethnographic research in two indigenous communities in Chile and Peru that are resisting high-impact project in their territory. He will also research the perceptions of communities nearby who have in the past accepted large projects and their CSR. In the return phase the researcher will consolidate the knowledge and experience gained in South America through advanced training and extensive fieldwork in community resistance and struggles for autonomy. Under the guidance of international experts, he will acquire an invaluable skill-set contrasting top-down development policies aimed at indigenous communities who demand a bottom-up solution that calls for more autonomy, this has clear implications for contemporary policy regarding indigenous peoples rights and development. The researcher will be based for two years at the Urban Sustainability Centre (CEDEUS) at the Universidad Católica de Chile, working under the supervision of Dr. Jonathan Barton. The third year of the Fellowship will be undertaken at the School of Natural Sciences, Trinity College Dublin (TCD) working under the supervision of Dr. Padraig Carmody.";212016,6;212016,6;H2020-MSCA-IF-2015;/MSCA-IF-GF;THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN;IE;;;;1;0;0;1;0;0 205228;703937;DaphNet;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Dynamic Preservation of Interactive Art: The next frontier of Multimedia Cultural Heritage;2017-02-01;2019-01-31;;"This project addresses the theoretical and methodological questions of embodied interaction with multimedia installation art through body movement and the use of mediation technology. The ultimate goal is the definition of an effective model for the preservation of interactive artworks, ensuring future re-use and flexible access. Most interactive artwork produced since the 1990s is lost due to the lack of adequate preservation methodologies: as a result the European cultural asset is impoverished and its potential for economic growth is drastically diminished. The intrinsic interconnection of interactive artworks with computer-based technology requires a multidisciplinary approach to preservation, involving high-profile cultural and scientific competences. With this project I intend to integrate my years of experience in the field of audio preservation with strategic competences that come from user-oriented studies in embodied cognition research, in order to bridge the gap between the world of the arts and the cutting-edge technology for digital preservation. This project contributes to the Work Programme H2020 by (1) canalizing advanced competences on the safeguard and the promotion of European cultural heritage, and by (2) bridging the gap between cutting-edge scientific-technological knowledge and the world of the arts, facilitating interdisciplinary innovation and strengthening the competitiveness of the European cultural and creative sectors (Official Journal of the European Union, L 347/225, Artt. 3a and 5.1).";160800;160800;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;UNIVERSITEIT GENT;BE;;;;1;0;0;1;0;0 205174;675662;QCALL;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2015-ETN;H2020;Quantum Communications for ALL;2016-12-01;2020-11-30;;"Quantum Communications for ALL (QCALL) endeavors to take the next necessary steps to bring the developing quantum technologies closer to the doorsteps of end users. Quantum communications (QC) is well-known for its offering ultra-secure cryptographic key-exchange schemes—resilient to any future technological advancement. QCALL will empower a nucleus of researchers in this area to provide secure communications in our continent and, in the long run, to our connections worldwide. With the large scale violations of privacy in the EU exchange of information, this is a crucial moment to pursue this objective. By covering a range of projects, with short, mid, and long-term visions, and using a balanced and multifaceted training programme, QCALL trains a cadre of highly qualified interdisciplinary workforce capable of shaping the R&D section of the field, hence accelerating its widespread adoption. This will ensure that EU will remain at the frontier of research on secure communications and advanced QC systems and devices. In QCALL, we explore the challenges of integrating quantum and classical communication networks; this will be essential in providing cost-efficient services. We experimentally examine and theoretically study new protocols by which network users can exchange secure keys with each other. We investigate disruptive technologies that enable wireless access to such quantum networks, and develop new devices and protocols that enable multi-party QC. Our meticulously planned training programme includes components from shared taught courses through to scientific schools and complementary-skill workshops, supplemented by secondment opportunities and innovative outreach and dissemination activities. This will create a structured model for doctoral training in EU that will last beyond the life of the project, so will the industry-academic collaborations that are essential to the development of the disruptive technologies that will make QC available to ALL.";3924884,52;3924884,52;H2020-MSCA-ITN-2015;/MSCA-ITN-ETN;UNIVERSITY OF LEEDS;UK;"UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6;HEINRICH-HEINE-UNIVERSITAET DUESSELDORF;UNIVERSITE DE GENEVE;UNIVERSITA DEGLI STUDI DI PADOVA;INSTITUT MINES-TELECOM;ID QUANTIQUE SA;TOSHIBA RESEARCH EUROPE LIMITED;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;UNIVERSIDAD DE VIGO;SORBONNE UNIVERSITE";"FR;DE;CH;IT;UK;ES";;1;0;0;1;0;0 198294;675512;BE-OPTICAL;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2015-ETN;H2020;Advanced BiomEdical OPTICAL Imaging and Data Analysis;2015-10-01;2019-09-30;;"Biomedical imaging is a research field that is producing ground breaking scientific discoveries that enhance the health and life quality of European citizens and have a huge economic impact. In order to maintain Europe’s leading position in the field, it is crucial to invest in the people who will lead R&D, and to promote the academic-private sector partnerships that will transfer the novel technologies to the market. In order to meet these needs, BE-OPTICAL will provide a unique and structured training programme to 14 ESRs in a wide range of optical imaging technologies and signal processing tools, including fluorescence spectroscopy and microscopy, optical coherence tomography, optogenetics, engineered nanomaterials and signal processing tools. The research is structured in 4 WPs: super-resolution optical imaging for the analysis of cellular processes (WP1), high-resolution optical imaging of cardiac tissue (WP2), advanced instrumentation for ophthalmic imaging (WP3), and optical components, methods and software for image analysis (WP4). Comprising 7 leading academic groups and 2 non-academic partners in 5 European countries, BE-OPTICAL brings together an interdisciplinary team of physicists, engineers and medical doctors, with complementary expertise in optical imaging, nanotechnology, computer science, complex systems and data analysis. The non-academic partners are a leading company in fluorescence instrumentation and an internationally recognised ophthalmology clinic, with the most advanced technology and expertise in ocular diseases. The training programme will provide the ESRs with a broad understanding of how a wide range of optical imaging technologies and data processing tools work, and will open for them a wide range of job opportunities. The ESRs will apply this knowledge to advance the early diagnosis of highly significant diseases. The ESRs will also gain insight into clinical studies of novel imaging technologies and the commercialization process.";3495300,48;3495300,48;H2020-MSCA-ITN-2015;/MSCA-ITN-ETN;UNIVERSITAT POLITECNICA DE CATALUNYA;ES;"INSTITUTO DE MICROCIRUGIA OCULAR DOS SLP;GEORG-AUGUST-UNIVERSITAET GOETTINGEN STIFTUNG OEFFENTLICHEN RECHTS;THE UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS;PICOQUANT INNOVATIONS GMBH;UNIVERSITY OF GLASGOW;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;UNIWERSYTET MIKOLAJA KOPERNIKA W TORUNIU;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS";"ES;DE;UK;PL;FR";;1;0;0;1;0;0 198160;646657;DynaSens;SIGNED;H2020-EU.1.1.;ERC-CoG-2014;H2020;Understanding the neural mechanisms of multisensory perception based on computational principles;2015-11-01;2020-10-31;;"The brain’s multisensory faculty provides considerable benefits for perception, as the adaptive weighting of multiple inputs increases perceptual reliability and flexibility. However, failure of this process results in an impoverished percept, and links to perceptual deficits that occur along our life span and in disorders such as Autism. While the brain efficiently handles multiple sensory inputs, we still have a limited understanding of the underlying neural mechanisms. To advance our knowledge of how the brain processes its environment I propose a pioneering agenda that departs from previous descriptive work by linking the underlying brain mechanisms with specific multisensory computations and perception. Precisely, I propose a programme that combines computational models of multisensory interactions with high-density neuroimaging and perceptual tasks. This interdisciplinary research builds on my pioneering multisensory work but will provide a qualitatively new and principled understanding of the neural processes that implement the well-known perceptual benefits of multisensory information. The proposed programme advances our knowledge by addressing the following timely questions: What are the neural processes transforming multiple sensory inputs to a unified representation guiding behaviour? How does the brain control the dynamic weighting of multiple inputs and assigns these to either a single or multiple causes? Which perceptual and neural processes are affected in the multisensory deficits seen in autistic individuals or the elderly? This agenda, by its innovative methods and deliverables, will offer a principled and comprehensive understanding of how the brain handles and merges multiple sensory inputs, and provides a framework for addressing continuing and pressing problems associated with multisensory processing deficits seen in cognitive disorders and during our life span.";1909441;1909441;ERC-2014-CoG;/ERC-COG;UNIVERSITAET BIELEFELD;DE;UNIVERSITY OF GLASGOW;UK;;1;0;0;1;0;0 198297;675530;ANSWER;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2015-ETN;H2020;ANtibioticS and mobile resistance elements in WastEwater Reuse applications: risks and innovative solutions;2015-10-01;2019-09-30;;In response to the increasing problem of water shortage, the reuse of treated urban wastewater is considered the most suitable and reliable alternative for sustainable water management and agricultural development. In spite of the benefits associated with this practice, major concerns currently exist, related to the adverse effects regarding chemical and biological contaminants of emerging concern such as antibiotics and mobile antibiotic resistance elements such as antibiotic resistant bacteria and resistance genes. These are now considered as a serious public health problem by various international organizations and the European Commission, because of their spread in the environment, the food chain, drinking water, etc. To tackle these problems, scientists with an interdisciplinary research/training background are urgently needed. This ETN will train a new generation of ESRs to address the risks associated with such contaminants and wastewater reuse. Innovative chemical, microbiological, toxicological and modelling tools, and novel process engineering will form the scientific and training core of their innovative research projects and training. The project will contribute to understanding the fate and transmission of antibiotics and resistance from wastewater to the environment and humans, through soil, ground/surface water and crops. Relevant ELVs will be determined, essential for the development and implementation of regulatory frameworks. This project directly tackles these aspects, by bringing together a multidisciplinary research team, with the private sector, and policy makers and through communication activities towards stakeholders and the wider public.;3708689,76;3708689,76;H2020-MSCA-ITN-2015;/MSCA-ITN-ETN;UNIVERSITY OF CYPRUS;CY;"UNIVERSITA DEGLI STUDI DI SALERNO;KWR WATER B.V.;TECHNISCHE UNIVERSITAET WIEN;THE AGRICULTURAL RESEARCH ORGANISATION OF ISRAEL - THE VOLCANI CENTRE;UNIVERSIDADE CATOLICA PORTUGUESA;AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS;ADVENTECH - ADVANCED ENVIRONMENTAL TECHNOLOGIES LDA;ENVIRONMENTAL INSTITUTE s.r.o.;TECHNISCHE UNIVERSITAET DRESDEN";"IT;NL;AT;IL;PT;ES;SK;DE";;1;0;0;1;0;0 197251;642892;NACCA;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2014-ETN;H2020;New Approaches in the Conservation of Contemporary Art;2015-06-01;2019-05-31;;The importance of European cultural heritage has been generally acknowledged. A significant part of this heritage, however, modern and contemporary art, runs a great risk of getting lost for future generations, because it is particularly difficult to preserve. Proper care requires resolving fundamental questions concerning the identity and authenticity of modern and contemporary artworks and the consequences for their conservation, rethinking historically grown professional distinctions as those between the curator and the conservator, re-organizing the institutional ecosystem, and establishing frameworks for international, interdisciplinary and intersectoral research and training collaboration. The aim of this Marie Curie Innovative Training Network is to educate a new generation of professional curators, conservators and academic researchers who are properly equipped to face these challenges. The key notion guiding the research and training programmes will be the notion of reflective practice. Starting from the theoretical framework of practice theory, the research programme will investigate conservation practices through the comparative analysis of their impact on modern and contemporary artworks’ biographies. The training programme will focus on the development of a reflective professional attitude, which is a pre-requisite in this increasingly complex and collaborative field.;3812140,8;3812140,8;H2020-MSCA-ITN-2014;/MSCA-ITN-ETN;UNIVERSITEIT MAASTRICHT;NL;"AKADEMIA SZTUK PIEKNYCH W WARSZAWIE;COMUNE DI MILANO;UNIVERSIDADE NOVA DE LISBOA;UNIVERSITA DEGLI STUDI ROMA TRE;THE BOARD OF TRUSTEES OF THE TATE GALLERY;UNIVERSIDADE DO PORTO;TECHNISCHE HOCHSCHULE KOLN;UNIVERSITY OF GLASGOW;UNIVERSITEIT VAN AMSTERDAM";"PL;IT;PT;UK;DE;NL";;1;0;0;1;0;0 221794;838680;BirthControlEnvirons;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Contraception meets the environment: everyday contraceptive practices, politics, and futures in a toxic age;2019-04-15;2021-04-14;;This action aims to conduct research among young women who are both feminists and environmentalists, and study how they negotiate these sensibilities in their striving for chemical-free contraception. Field research will be carried out in France, a place where on the one hand environmentalism is characterized by a strong concern with toxic chemicals in everyday life and, on the other, where access to the contraceptive pill remains an emblematic victory of second wave feminism, and by far the most prescribed contraceptive method nationwide. Theoretically, this project will contribute to the anthropology of chemicals, an emergent and cutting-edge subfield of research, and to the growing public debate regarding the ‘crisis’ of the contraceptive pill. Findings will be disseminated through seminars and publications that help push the boundaries of the discipline, a short documentary film that will appeal to wider audiences, and a few, carefully designed interdisciplinary activities that will bridge the domains of academia, arts, activism, and policy.;184707,84;184707,84;H2020-MSCA-IF-2018;/MSCA-IF-EF-ST;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FR;;;;1;0;0;1;0;0 221802;842536;AEROSIMULAT;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;High-performance aerodynamics and aeroacoustics simulations of the new generation of high-speed gas turbines via high-order Galerkin methods;2020-09-01;2023-08-31;;"The main goal of this project is to perform efficient and accurate simulations of the turbulent compressible flow and generated noise on the new high-speed gas turbines at operation conditions, with the aim of supporting engineers in the design of efficient engines and effective noise reduction solutions. The main difficulty is to correctly simulate, in an acceptable wall- clock time, high Reynolds and high Mach numbers turbulent flows with important regions of separation and the different length scales and amplitudes among the acoustic and the flow fields. In this project we propose to tackle these problems by introducing high-order Galerkin methods and a skin friction boundary condition technique extended to compressible flows. Both techniques demonstrated impressive performance results on a different context. Given the fellow’s expertise in compressible flows, and her Third Country host’s expertise in high-order Galerkin methods, we are in a unique position to advance in the solution of this problem. A high performance computing simulation tool developed at the host institution will be used and developed as open source within this project. To go one step further within this interdisciplinary subject, we will establish a close collaboration with CTA, a company in the host country specialized in testing aerospace materials, where the fellow will spend one month of research. During this visit, the simulation results of their turbine prototypes will be analyzed and will be validated against their experimental data. The fellow will extend her network in the scientific and industrial communities. She will gain new managerial skills and a scientific maturity that will open her doors to obtain a strong research position in Europe. The host and the Third Country host supervisors will also benefit from the advances of this promising collaboration. The obtained results are expected to lead to further research and enhance the prospects of new projects.";245732,16;245732,16;H2020-MSCA-IF-2018;/MSCA-IF-GF;BCAM - BASQUE CENTER FOR APPLIED MATHEMATICS;ES;;;;1;0;0;1;0;0 221768;818450;MERIR;SIGNED;H2020-EU.1.1.;ERC-2018-COG;H2020;Methane related iron reduction processes in sediments: Hidden couplings and their significance for carbon and iron cycles;2019-04-01;2024-03-31;;"About one-third of annual methane (CH4) emissions to the atmosphere originate from natural, nonanthropogenic sources. However, if all the naturally produced methane actually did reach the atmosphere, its levels would increase by an order of magnitude, dwarfing anthropogenic CO2 emissions. Fortunately, natural scavengers of this methane near its production zone limit its release. One of these scavengers, iron (Fe) oxide, can become a major sink for methane when sulfate concentrations are low. Methane-iron couplings in established sediments, however, are poorly understood. Specifically, significant iron oxide reduction has been observed in many aquatic sediments at depths well below its expected redox zone, where methane is produced by methanogenesis, often accompanied by decreases in methane concentrations. These observations challenge our understandings of iron-methane couplings and microbial players in the deep methanogenic zone and their impacts on the carbon, iron and other cycles. I aim in the proposed research to elucidate the unexplored mechanisms of methane-related iron reduction (MERIR) in the methanogenic zone of established sedimentary profiles under various environmental conditions and their impact on global biogeochemical cycles. I will resolve two striking yet unexplained phenomena: (1) the active involvement of aerobic methanotrophs in iron-coupled anaerobic oxidation of methane (AOM), and (2) the unusual reactivity of iron minerals toward reduction that is accompanied by intensive authigenic magnetite precipitation, and the effects of this mineralogy change on sedimentary magnetism. My expertise will enable me to achieve the objectives of this interdisciplinary proposed work using novel approaches from different fields. The project will likely lead to breakthroughs in our understanding of microbial survival strategies, reveal novel pathways for aerobic methanotrophs, and change our perspectives on iron mineral reactivities and sedimentary magnetism.";2000000;2000000;ERC-2018-COG;/ERC-COG;BEN-GURION UNIVERSITY OF THE NEGEV;IL;;;;1;0;0;1;0;0 221785;838997;X-MIXING;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Efficient mixing method at the microscale for Time-Resolved Serial Femtosecond Crystallography;2019-09-01;2022-01-31;;X-MIXING is an interdisciplinary project aimed at conceiving an efficient mixing method at the microscale suitable for triggering not-light sensitive biochemical reactions in the application of Time-Resolved Serial Femtosecond Crystallography. Nowadays, the temporal resolution of this type of dynamic structural biology analysis with X-ray Free-Electron Lasers is limited by the minimum mixing time that current methods can produce. As it is shown in a proof-of-concept, an exciting combination of electrohydrodynamic fields and momentum transfer lead to a significant variation of the spatiotemporal scales within the convection-diffusion mechanism. So, this configuration can potentially generate mixing from 100 to 1000 faster than current means do. Besides, its versatility would enable not only to reduce the mixing time substantially, but also to induce jumps in PH and temperature that would additionally open horizons concerning new types of triggering reactions in the field. These critical features have the potential to become this original configuration in a key to take full advantage of the recent significant investment, over 1,22 billion euro (2005 value), paid by European Union and partners for the construction of the European XFEL (Germany), whose user operation started in September 2017. To explore and elucidate the underlying physical limits of the proposed method, the research methodology of this project will embrace different approaches such as micro-PIV experiments, numerical simulations, and scaling analysis.;197529,6;197529,6;H2020-MSCA-IF-2018;/MSCA-IF-GF;UNIVERSIDAD DE SEVILLA;ES;;;;1;0;0;1;0;0 221771;820188;NanoMechShape;SIGNED;H2020-EU.1.1.;ERC-2018-COG;H2020;Molecular control of actin network architecture and mechanics during cell shape changes;2019-05-01;2024-04-30;;"Precise control of shape is key to cell physiology, and cell shape deregulation is at the heart of many pathologies. As cell morphology is controlled by forces, studies integrating physics with biology are required to truly understand morphogenesis. NanoMechShape will take such an interdisciplinary approach to investigate the regulation of animal cell shape. In animal cells, actin networks are the primary determinants of shape. Most cell shape changes fall into two categories: 1) those driven by contractions of the actin cortex, a thin network underlying the membrane in rounded cells; and 2) those resulting from transitions between the cortex and other actin networks, such as lamellipodia and filopodia. To understand cell deformations, it is thus essential to understand the regulation of cortex contractile tension and the mechanisms controlling transitions in actin architecture. NanoMechShape will comprise three aims. First, we will explore how cortex tension is regulated. We will focus on the role of cortex architecture, which remains elusive due to the difficulty in probing the organisation of the thin cortical network. We will unveil cortex architecture using super-resolution and electron microscopy, and systematically investigate how nanoscale architectural features affect tension. Second, we will explore how the identified regulatory mechanisms contribute to the establishment of a cortical tension gradient. We will focus on the gradient driving cytokinetic furrow ingression, an exemplar tension-driven shape change. Third, we will investigate transitions in actin architecture underlying cell spreading. We will compare spreading at the end of mitosis and during differentiation of mouse embryonic stem cells, paving the way to investigations of the crosstalk between cell shape and fate. By bridging a fundamental gap between molecular processes and cell-scale behaviors, our multidisciplinary study will unveil some of the fundamental principles of cell morphogenesis.";1943071;1943071;ERC-2018-COG;/ERC-COG;THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;UK;;;;1;0;0;1;0;0 217752;811208;MSCA 2018;SIGNED;H2020-EU.1.3.5.;IBA-MSCA-Presidency-Conf-2017;H2020;Marie Sk³odowska-Curie Actions - Beyond 2020;2018-03-01;2018-12-31;;"The purpose of Marie Sk³odowska-Curie Actions / MSCA is to bring together organisations such as Universities, SMEs (small/medium enterprises), public and private (non-commercial) research centres, non-profit organisations etc. in order to train early-stage researchers in professional environments. MSCA • Encourage researchers to explore multidisciplinary and interdisciplinary avenues in responding to current and future challenges; • Enhance researchers’ career prospects and exposure to both academic and non-academic fields, through international and intersectoral mobility; • Convert knowledge and ideas into products and services for economic and social benefit; • Provide researchers with a set of transferrable skills for the purpose of innovation and long-term employability. Better preparation for work in business, industry and the public and private sectors, effectively moving away from the focus of research as being purely academically centred can be attained. MSCA celebrated their 20th anniversary in 2016. The past 20 years have shown how flexible these actions were adapted to current demands and needs of researchers and the research community. While the focus on the research theme and the project is prevailing the career development scheme has a strong meaning. The work programme for the last three years of Horizon 2020 and therefore MSCA was adopted; the next two years will be implemented as up to now. The third and last year will be depending on the discussions on the next Framework Programme and underline the expected transition period and therefore relevant projects helping to change from one scheme to the other. The draft of the next Framework Programme is expected to be released in May 2018 and will subsequently be one of the priorities during the Austrian Council Presidency. This gives the opportunity to discuss the draft and to gather input from different stakeholders relevant to the process and to the scientific and research community.";237500;150000;H2020-IBA-MSCA-Presidency-Conf-2017;/CSA;BUNDESMINISTERIUM FUER DIGITALISIERUNG UND WIRTSCHAFTSSTANDORT;AT;OEAD (OSTERREICHISCHE AUSTAUSCHDIENST) GESELLSHAFT MIT BESCHRANKTER HAFTUNG - AUSTRIAN AGENCY FOR INTERNATIONAL COOPERATION IN EDUCATION AND;AT;;1;0;0;1;0;0 214783;778322;CARE4C;SIGNED;H2020-EU.1.3.3.;MSCA-RISE-2017;H2020;Carbon smart forestry under climate change;2018-01-01;2021-12-31;;Carbon smart forestry under climate change (CARE4C) combines high level expertise and state of the art research in the context of carbon management in forests with advanced career building qualification by teaching, training and involving ESR's . CARE4C aims at substantially expanding knowledge about carbon sink by forest growth and carbon source by forest operations in order to enable carbon smart forestry under climate change. We trace the knowledge from understanding to modelling and application, and follow a clear dissemination strategy by training and teaching, publications in scientific journals and by involving forest related stakeholders and the public. The project builds upon a consortium that was successfully established within the Marie Curie IRSES project Climate-Fit Forests. Here, the consortium is enlarged by complementary academic and non-academic partners, and the exploratory focus is extended. The study area encompasses a broad range of climatic zones from Mediterranean to sub-boreal areas providing highly different growing conditions and landscapes differently affected by climate change. By this multilevel and multidisciplinary approach we overcome the restrictions concerning the transferability of locally and case study focused results. We plan a rather high number of secondments in order to efficiently extend the interdisciplinary network and dissemination. The project connects countries where both, integrative and segregative approaches, are prevailing in forest management. The forest types of interest include pure and mixed stands as well as complex structured close to nature forests. We track climate induced impacts on carbon sequestration on cell, organ, and tree level up to stand and landscape level. For a broad spectrum of forest types and management approaches we measure and compile information about carbon sink and source, model the carbon balance, take into account economics and derive carbon smart forest management options under climate;967500;967500;H2020-MSCA-RISE-2017;/MSCA-RISE;TECHNISCHE UNIVERSITAET MUENCHEN;DE;"UNIVERSIDAD DE VALLADOLID;SZKOLA GLOWNA GOSPODARSTWA WIEJSKIEGO;BERNER FACHHOCHSCHULE;Ministerium für Klimaschutz, Umwelt, Landwirtschaft, Natur- und Verbraucherschutz des Landes Nordrhein-Westfalen;INSTITUTO NACIONAL DE INVESTIGACION Y TECNOLOGIA AGRARIA Y ALIMENTARIA OA MP;UNIVERSITA DEGLI STUDI DI PADOVA;GROSSE KREISSTADT TRAUNSTEIN;BURGERGEMEINDE BERN;AGRESTA S COOP;LIBERA UNIVERSITA DI BOLZANO;FORA FOREST TECHNOLOGIES SLL;BIALOWIESKI PARK NARODOWY;PROVINCIA AUTONOMA DI BOLZANO";"ES;PL;CH;DE;IT";;1;0;0;1;0;0 216316;801055;CHIRON;SIGNED;H2020-EU.1.2.1.;FETOPEN-01-2016-2017;H2020;Spin Wave Computing for Ultimately-Scaled Hybrid Low-Power Electronics;2018-05-01;2021-04-30;;"The future miniaturisation of electronic circuits following Moore’s law will require the introduction of increasingly disruptive technologies to limit power consumption and optimise performance per circuit area. CHIRON envisions spin wave computing to complement and eventually replace CMOS in future microelectronics. Spin wave computing is a paradigm-shifting technology that uses the interference of spin waves for computation. Spin wave computing has the potential for significant power and area reduction per computing throughput while reducing cost by alleviating lithography requirements. As a first step towards the vision of a full spin wave computer, CHIRON envisions hybrid spin wave–CMOS circuits that can be readily integrated alongside CMOS. CHIRON targets a proof of principle of the essential elements for spin wave computing by an interdisciplinary approach joining partners with expertise in material science, physics, nano-manufacturing, electrical engineering, device simulation, and circuit design. CHIRON will fabricate basic logic gates, such as inverters and majority gates, demonstrate their operation, and assess their performance. As transducers between the CMOS and spin wave domains in hybrid circuits, CHIRON will develop magnetoelectric and multiferroic nanoresonators, based on nanoscale bulk acoustic resonators, which bear promise for high energy efficiency and large output signal. The targeted lateral scale (100 nm) and resonance frequency (>10 GHz) bring such resonators to the frontier of nano-electromechanical systems (NEMS). This technological proof of principle is complemented by the design of digital hybrid spin wave–CMOS circuits that show the advantages of spin wave computing and can be integrated into a CMOS environment. Based on calibrated compact device models, the performance of these circuits in terms of power, area, and throughput will be benchmarked against CMOS to demonstrate their viability.";3745607,5;3745607,5;H2020-FETOPEN-1-2016-2017;/RIA;INTERUNIVERSITAIR MICRO-ELECTRONICA CENTRUM;BE;"SOLMATES BV;FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS;UNIVERSITE PARIS-SUD;TECHNISCHE UNIVERSITAET KAISERSLAUTERN;INSTITUTUL NATIONAL DE CERCETAREDEZVOLTARE PENTRU MICROTEHNOLOGIE;THALES SA;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;TECHNISCHE UNIVERSITEIT DELFT";"NL;EL;FR;DE;RO";;1;0;0;1;0;0 216327;801215;TRAINEd;SIGNED;H2020-EU.1.3.4.;MSCA-COFUND-2017;H2020;TRAIN@Ed;2018-06-01;2023-05-31;;"TRAIN@Ed is a research fellowship programme for 25 experienced researchers (around 4 -6 years after gaining their primary degree) which will provide researchers with an international, interdisciplinary and intersectoral mobility experience. The TRAIN@Ed programme will educate experienced researchers in research excellence AND transferrable skills. TRAIN@Ed Fellows will have an employment contract with the University of Edinburgh for a research fellowship for up to three years. TRAIN@Ed fellows will pursue research and transferrable skill training at the University of Edinburgh, and will also spend some time in the industry of their choice. At the end of the TRAIN@Ed programme, TRAIN@Ed alumni will have the knowledge, skills and experience for fulfilling and productive careers either in academia OR in industry. The values of the scheme align with those held by Horizon 2020: Excellent Sciences, Industrial Leadership and addressing Societal Challenges, and the Marie-Sk³odowska Curie Actions of providing excellent, innovative research training and career progressive and knowledge exchange and mobility opportunities. Although the focus of the TRAIN@Ed programme is in developing research skills through carrying out a research project, a holistic approach to career development of the researchers will be taken: the programme will provide mentoring, transferrable skill development (including public engagement training), and careers advice. TRAIN@Ed delivers in important areas of experienced researcher development in the European Union: Firstly, it provides a highly visible research opportunity for experienced researchers, with secure employment for three years. Secondly TRAIN@Ed addresses a major gap in opportunities for early career researchers to collaborate with industry. Thirdly, TRAIN@Ed complies with best practice in supporting researcher careers. TRAIN@Ed will benefit the researchers, the University of Edinburgh and the European economy.";5310000;2655000;H2020-MSCA-COFUND-2017;/MSCA-COFUND-FP;THE UNIVERSITY OF EDINBURGH;UK;;;;1;0;0;1;0;0 213201;783287;Engage;SIGNED;H2020-EU.3.4.7.;SESAR-ER3-01-2016;H2020;Knowledge Transfer Network proposed in response to the SESAR-ER3-01-2016 Call;2018-01-01;2021-12-31;;Engage is a KTN proposed for European air traffic management, building on the solid foundation of previous actions, and introducing novel features and actions. Previous attempts to involve industry in the earlier maturity phases of ATM research have only partly been successful. We recognise that additional actions and incentives are necessary. With a balanced consortium, permeating all features of our proposal is the pronounced and active engagement of industry partners. At the core of the network are thematic challenges, supported by dedicated workshops. Catalyst funding will support focused projects, thus stimulating the transfer of exploratory research results towards ATM application-oriented research. This approach is enabled by the budget released through our lean management and compact consortium team. The network will establish a knowledge hub, in which members across the research community are continuously involved. This will include an observatory and undertake the role of devising and maintaining the long-term roadmap development of innovative and interdisciplinary ATM concepts beyond SESAR 2020. The knowledge hub will be the one-stop, go-to source for information in Europe. Our vision of the network is that of an enduring partnership between academic, operational and industrial partners exchanging needs, ideas and information to ensure the relevance and applicability of research and uptake of new concepts and methods.;5120300;3971875;H2020-SESAR-2016-2;/SESAR-CSA;THE UNIVERSITY OF WESTMINSTER LBG;UK;"UNIVERSITA DEGLI STUDI DI TRIESTE;Univerzitet u Beogradu - Saobracajni fakultet;EUROCONTROL - EUROPEAN ORGANISATION FOR THE SAFETY OF AIR NAVIGATION;FREQUENTIS AG;FUNDACION INSTITUTO DE INVESTIGACION INNAXIS;EUROPEAN AVIATION SAFETY AGENCY;TECHNISCHE UNIVERSITEIT DELFT";"IT;RS;BE;AT;ES;DE;NL";;1;0;0;1;0;0 211867;764434;PRe-ART;SIGNED;H2020-EU.1.2.1.;FETOPEN-01-2016-2017;H2020;Predictive Reagent Antibody Replacement Technology;2017-09-01;2021-08-31;;"Predictive Reagent Antibody Replacement Technology (PRe-ART) will create a foundational new technology platform to completely replace conventional antibody technology within medical diagnostics and basic life science research. In a multidisciplinary approach combining basic science, protein engineering and computational prediction, Pre-ART will generate non-antibody components which can be combined in an entirely modular fashion to create molecules that bind any peptide of choice. Such a biotechnological revolution is timely because of current failings in the reagent antibody market, after forty years still based on monoclonal antibodies (mAbs) to detect biomolecules, when 50% of all commercial reagent mAbs have been shown to not function correctly. By combining information science with directed evolution, PRe-ART will ultimately create an encyclopedia of pre-designed and experimentally pre-selected modules (like biological Lego bricks) that may be combined, without any further experiment, to generate unique binding molecules that function as antibody replacements. The PRe-ART vision is that mAbs for many applications in biological research will be replaced over the course of a decade by these designer molecules, with the potential to completely disrupt the industry selling low-quality commercial animal-derived reagent antibodies, and thus create a major new technology for biological research. Thus, PRe-ART will ultimately contribute not only to the health and wellbeing of the EU citizen through improved diagnostic capability, but also to the economy of the EU through the development of myriad detection products, enabled by this foundational platform technology. The interdisciplinary PRe-ART project will achieve this goal by bringing together three leading labs from different fields, two of which are lead by women PIs, whose joint efforts will achieve this breakthrough S&T target. The PRe-ART project thus closely addresses all specific challenges of the call.";3588125;3588125;H2020-FETOPEN-1-2016-2017;/RIA;UNIVERSITAT ZURICH;CH;"UNIVERSITAET BAYREUTH;ASTON UNIVERSITY";"DE;UK";;1;0;0;1;0;0 209149;725172;SIRFUNCT;SIGNED;H2020-EU.1.1.;ERC-2016-COG;H2020;Chemical Tools for Unravelling Sirtuin Function;2017-04-01;2022-03-31;;"It was recently realized that lysine acetylation affects a wide variety of cellular processes in addition to the initially recognized histone related gene regulation. Together with recent groundbreaking results, revealing the presence of additional acyllysine modifications, the basis for a paradigm shift in this area was formed. Examples of enzymes formerly thought to be lysine deacetylases, have been shown to cleave these new types of lysine modification and members of the sirtuin class of enzymes play a central role. Development of new tools to investigate the importance of these new modifications as well as the sirtuins that cleave them is required. We therefore propose to adopt an interdisciplinary approach by developing selective inhibitors and so-called activity-based probes (ABPs) and applying these to the investigation of proteins recognizing novel post-translational acylations of lysine residues in cells. Such ABPs will be powerful tools for providing insight regarding this rapidly evolving area of biochemistry; however, the current state-of-the-art in ABP design is endowed with severe limitations because the modifications are inherently cleaved by various hydrolases in human cells. Thus, in the present project, I propose that novel designs accommodating non-cleavable modifications are warranted to maintain structural integrity during experiments. Furthermore, I propose to apply similar mechanism-based designs to develop potent and isoform-selective sirtuin inhibitors, which will serve as chemical probes to investigate links between cancer and metabolism, and may ultimately serve as lead compounds for pre-clinical pharmaceutical development. AIM-I. (a) Development and (b) application of collections of chemical probes for activity-based investigation of enzymes that interact with post-translationally acylated proteins. AIM-II. Utilization of structural and mechanistic insight to design potent and selective inhibitors of sirtuin enzymes.";1758742;1758742;ERC-2016-COG;/ERC-COG;KOBENHAVNS UNIVERSITET;DK;;;;1;0;0;1;0;0 208113;725128;CIC;SIGNED;H2020-EU.1.1.;ERC-2016-COG;H2020;Context, Identity and Choice: Understanding the constraints on women's career decisions;2017-07-01;2022-06-30;;There has been vast improvement in workplace gender equality, but there remain marked differences in the roles in which women and men work. Explanations for this inequality have focused on the barriers women face. However, as women begin to enter male-dominated roles, a new explanation has arisen: that remaining gender inequality must reflect fundamental differences between women and men, including differences in (a) ambition and desire for power, (b) needs for work-life balance, and (c) willingness to take career risks. Central to this analysis is the assumption that the glass ceiling is broken and thus inequality must be due to women’s active choices. This explanation downplays the fact that social context continues to be a barrier to women’s success and places responsibility for gender inequality on women themselves. Indeed, there has arisen the suggestion that gender equality necessitates women overcoming ‘internal obstacles’, ‘leaning-in’ and altering their choices (Sandberg, 2013), rather than challenging the status quo. I argue that diametrically contrasting structural barriers with women’s choices is unhelpful. Instead, I suggest that women’s choices are shaped and constrained by the gendered nature of organisational and social contexts and how women see themselves within these contexts. I propose a programme of research, across 3 integrated streams, that investigates how social and organisational structures define identities and constrain women’s choices in relation to ambition, work-life balance, and career risk-taking. I have four key objectives: (1) to clarify how organisational and social contexts define identity and constrain women’s choices, (2) to use an interdisciplinary, multi-methodological approach, to produce innovative theory and data, (3) to work collaboratively with stakeholders, and (4) to inform practical interventions designed to facilitate the increase of women’s participation in hitherto male-dominated roles.;1998722;1998722;ERC-2016-COG;/ERC-COG;THE UNIVERSITY OF EXETER;UK;;;;1;0;0;1;0;0 207432;730989;IDEAAL;SIGNED;H2020-EU.1.4.1.1.;INFRADEV-03-2016-2017;H2020;International Development of gAnil-spirAL2;2017-01-01;2019-12-31;;"The objectives of the IDEAAL Project are to explore all possibilities to develop GANIL infrastructure, with its new ESFRI SPIRAL2 facility, in order to ensure its long-term sustainability as one of the premiere European research institutes for nuclear physics, interdisciplinary sciences and related applications. The first objective of the IDEAAL Project is to enlarge the present GANIL membership to include academic institutions and private funding partners. This enlargement goes hand-in-hand with a reinforcement of the involvement of the current institutional funders and academic users of GANIL-SPIRAL2 in the decision-making process and management of the facility. The second objective of IDEAAL is to enhance the excellence of access to the infrastructure by optimizing support to the users, access policy, assessment on the cost of access to the facilities and to data, improvement of the performance capabilities as well as exchange and training of personnel with associated partners. Innovation is the third objective of IDEAAL. With the new facility SPIRAL2, it is essential to encourage industrial users of the uniqueness of this new machine for their research and applications and to allow them to develop new experimental tools at the existing GANIL facilities. Access provision dedicated to industrial users will greatly enhance their experience and increase their interest and trust in GANIL-SPIRAL2. In parallel, new ideas and topics for technology transfer will be clearly identified. The increase of innovation potential of GANIL will also be evaluated. These three objectives must be supported by a strong communication and outreach policy towards members and funding partners, users and the layman. This is the fourth objective of the project. Fulfilling all of these four objectives will allow a well-organized, highly efficient and sustainable development of the current GANIL structure.";3883390;3883390;H2020-INFRADEV-2016-1;/CSA;GRAND ACCELERATEUR NATIONAL D'IONS LOURDS;FR;"COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES;THE HENRYK NIEWODNICZANSKI INSTITUTE OF NUCLEAR PHYSICS, POLISH ACADEMY OF SCIENCES;GSI HELMHOLTZZENTRUM FUER SCHWERIONENFORSCHUNG GMBH;NUCLEOPOLIS POLE NORMAND DES SCIENCES NUCLEAIRES ET DE LEURS APPLICATIONS;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS";"FR;PL;DE";;1;0;0;1;0;0 207044;734370;BESTOFRAC;SIGNED;H2020-EU.1.3.3.;MSCA-RISE-2016;H2020;Environmentally best practices and optmisation in hydraulic fracturing for shale gas/oil development;2017-01-01;2020-12-31;;"This research brings together the complementary expertise of our consortium members to gain a better understanding of the physics in hydraulic fracturing (HF) with the final goal to optimize HF practices and to assess the environmental risks related to HF. This requires the development and implementation of reliable models for HF, scaled laboratory tests and available on-site data to validate these models. The key expertise in our consortium is on modelling and simulation of HF and all partners involved pursue different computational approaches. However, we have also some partners in our consortium which focus on scaled laboratory tests and one company which can provide on-site data. The choice of the best model for HF still remains an open question and this research promises to quantify uncertainties in each model and finally provide a guideline how to choose the best model with respect to a specific output parameter. The final objective is to employ these models in order to answer some pressing questions related to environmental risks of HF practices, including 1. How does HF interact with the natural fractures that intersect the shale seam?’ 2. How does the fracture network from a previous stage of HF treatment affect the fracture network evolution in succeeding, adjacent stages? 3. What are the requirements to constrain fractures from propagating to the adjacent layers of confining rock? The exchange and training objectives are to: 4. Enhance the intersectoral and interdisciplinary training of ERs and ESRs in Computational Science, Mining Geotechnics, Geomechanics, Modeling and Simulation 5. Strengthen, quantitatively and qualitatively, the human potential in research and technology in Europe 6. Advance the scientific contribution of women researchers in this area dominated by male 7. Create synergies with other EU projects 8. Enable and support all ESRs/ERs to keep contact with international community in the sense of training and transfer of knowledge";1930500;1669500;H2020-MSCA-RISE-2016;/MSCA-RISE;BAUHAUS-UNIVERSITAET WEIMAR;DE;"UNIVERSITY OF DURHAM;inuTech GmbH;TECHNISCHE UNIVERSITEIT EINDHOVEN;CISM-LAB SRL;GOTTFRIED WILHELM LEIBNIZ UNIVERSITAET HANNOVER";"UK;DE;NL;IT";;1;0;0;1;0;0 206030;731861;iMuSciCA;SIGNED;H2020-EU.2.1.1.;ICT-22-2016;H2020;Interactive Music Science Collaborative Activities;2017-01-01;2019-06-30;;"iMuSciCA will – through engagement in music activities – support mastery of core academic content on STEM subjects (Physics, Geometry, Mathematics, and Technology) for secondary school students (aged 12-16) alongside with the development of their creativity and deeper learning skills. To reach this goal, iMuSciCA introduces new methodologies and innovative technologies supporting active, discovery-based, collaborative, personalised, and more engaging learning. These technologies provide students and teachers with opportunities for collaboration, co-creation, and collective knowledge building. In particular, iMuSciCA will deliver a suite of software tools and services on top of market-ready new enabling technologies integrated on a web-based platform. These include: a 3D design environment for personalized virtual musical instruments; advanced music generation and processing technologies to apply and interpret related physics and mathematics principles; gesture and pen-enabled multimodal interaction functionality for music co-creation and performance; and 3D printing for realizing the actual/tangible physical instrument. The platform will be complemented with a suite of interdisciplinary project/problem based educational scenarios for STEAM integrating innovative and stimulating methods in teaching and learning. The iMuSciCA framework will be pilot-tested and evaluated in real learning contexts by a substantial number of students and teachers in three European countries (Belgium, Greece, and France). The project will be implemented in close collaboration of academic and industrial partners, bringing together existing technologies and promoting ground-breaking research in STEAM pedagogy and the involved core enabling technology. As such, iMuSciCA will be a pioneering approach using music for fostering creativity and deeper learning, thereby setting new grounds in the European curricula of STEAM.";3224970;2673745;H2020-ICT-2016-1;/RIA;ATHINA-EREVNITIKO KENTRO KAINOTOMIAS STIS TECHNOLOGIES TIS PLIROFORIAS, TON EPIKOINONION KAI TIS GNOSIS;EL;"Cabrilog SAS;INSTITUT DE RECHERCHE ET DE COORDINATION ACOUSTIQUE MUSIQUE - IRCAM;3D FOR ALL SZAMITASTECHNIKAI FEJLESZTO KFT;UC LIMBURG;MATHS FOR MORE SL;UNIVERSITE DE FRIBOURG;ELLINOGERMANIKI AGOGI SCHOLI PANAGEA SAVVA AE";"FR;HU;BE;ES;CH;EL";;1;0;0;1;0;0 206365;732489;CRISS;SIGNED;H2020-EU.2.1.1.;ICT-22-2016;H2020;Demonstration of a scalable and cost-effective cloud-based digital learning infrastructure through the Certification of digital competences in primary and secondary schools;2017-01-01;2019-12-31;;"CRISS is a user-driven, flexible, scalable and cost-effective cloud-based digital learning ecosystem that allows the guided acquisition, evaluation and certification of digital competences in primary and secondary education, and easily scalable to other educational levels. CRISS proposes an innovative adaptive learning solution supported by the most advanced pedagogical methodologies and technologies that will be tested with a very large scale pilot with more than 490 schools including 25.400 students and 2.290 teachers across Europe. CRISS aim to contribute to the modernisation of the educational and training system at different levels: a) Support schools and educational institutions in the definition and creation of a curricular programming aligned to European and national policies, encouraging the active participation of all teachers and creating an interdisciplinary framework and highly diversified contents, activities and educational experiences for the acquisition and evaluation digital competences of students. b) Offers teachers and students an adaptive and intelligent environment for personalizing the process of teaching and learning that allows them to easily and dynamically generate and integrate programming a wide variety of new learning experiences and integrate new methodologies, fostering a creative and motivating use of technologies focused on minimizing the distance between digital competences acquired at school and the required in the labour market. c) Through its learning analytics module CRISS can generate an innovative and unique student ICT Dynamic Profile, showing strengths and weaknesses, achievements, interests, skills acquired, certification and other recognition, on the one hand facilitating the personalization of teaching / learning, and on the other the entry into the labour world. d) Thanks to its evaluation and certification of digital competences will contribute to the standardization of digital competences at European level.";5951456,62;4872336,25;H2020-ICT-2016-1;/IA;EXUS SOFTWARE LTD;UK;"ESCOLA PIA DE CATALUNYA;COMUNIDAD FORAL DE NAVARRA - GOBIERNO DE NAVARRA;DIGINEXT;SVEUCILISTE U ZAGREBU, FAKULTET ORGANIZACIJE I INFORMATIKE;DOCUMENTA CREACIONES MULTIMEDIA AVANZADAS SL;EDUCATION4SIGHT GMBH;FUNDACIO PER A LA UNIVERSITAT OBERTA DE CATALUNYA;SOCIEDAD ANDALUZA PARA EL DESARROLLO DE LAS TELECOMUNICACIONES SA;HRVATSKA AKADEMSKA I ISTRAZIVACKA MREZA CARNET;PERIFERIAKI DIEFTHINSI PROTOVATHMIAS KAI DEFTEROVATHMIAS EKPAIDEFSIS KRITIS;HÄLSINGLANDS UTBILDNINGSFÖRBUND;FONDAZIONE HALLGARTEN-FRANCHETTI CENTRO STUDI VILLA MONTESCA;UNIVERSITY COLLEGE LONDON;INSPECTORATUL SCOLAR JUDETEAN ARAD";"ES;FR;HR;DE;EL;SE;IT;UK;RO";;1;0;0;1;0;0 205553;722171;BioCapture;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2016;H2020;Smart capture phases for proteomics, glycomics and biomarker assays;2016-11-01;2020-10-31;;"The overall objective of BioCapture is to develop novel robust assays for proteinaceous biomarkers associated with cancer and to develop innovative tools for assaying elusive cancer related posttranslational modifications in proteins. This will be achieved by exploiting robust glycan, peptide and protein binders in the form of Molecularly Imprinted Polymers (MIPs) or plastic antibodies alongside generic enrichment combined with selected reaction monitoring-based mass spectrometry assays. In addition, sequence specific MIPs for multiple proteotypic peptides will be developed for use as capture phases in array format followed by MS or fluorescence based readout as well as a coupling of both detection techniques. The artificial receptors will be developed by various Molecular Imprinting techniques. The research results will lead to technological advances having a major impact on 1) health care since it will profit from methods for earlier, more reliable diagnosis of diseases, 2) drug discovery allowing a faster target or biomarker identification; and 3) biochemistry research laboratories in resulting in improved protein fractionation tools for revealing low abundant post translational modifications. The training of researchers will be performed by a consortium consisting of in total 15 partners whereof 6 polymer/materials research groups, 5 protein/glycan chemistry/analysis groups, 1 separation technology companies, 2 expert groups on platforms for multiplex analysis and one diagnostic company. This forms the basis for a very exciting interdisciplinary training program. Thus 11 early stage researchers (ESRs) working on specific tasks within five work packages will follow a rich training program providing a well-balanced spectrum of scientific, business and entrepreneurial skills.";2982879;2982879;H2020-MSCA-ITN-2016;/MSCA-ITN-ETN;MALMO UNIVERSITET;SE;"LINNEUNIVERSITETET;KOBENHAVNS UNIVERSITET;UMEA UNIVERSITET;BUNDESANSTALT FUER MATERIALFORSCHUNG UND -PRUEFUNG;SYDDANSK UNIVERSITET;UNIVERSITETET I OSLO;UNIVERSITY OF STRATHCLYDE";"SE;DK;DE;NO;UK";;1;0;0;1;0;0 204923;704837;WINDASH;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-GF;H2020;Wireless with Increased Network Density, Antennas, Spectrum and Heterogeneity;2016-09-12;2019-11-20;;"'The H2020 'Digital Agenda for Europe” Flagship Initiative has the goal of providing all EU citizens with Internet speeds above 30Mbps and above 50% households above 100Mbps. Delivering such speeds and reaching so many households will require the creation of a new generation of wireless access networks. This action will study Wireless with Increased Network Density, Antennas, Spectrum and Heterogeneity (W.I.N.D.A.S.H.). Wireless communications increasing these resources received little attention in the past due to technical difficulty. However, traditional wireless systems with not-so-large bandwidth, antenna arrays and density are operating close to the capacity limit and research must move on to higher frequency bands, antenna architectures with massive numbers of elements, and increased device density, in order to deliver new significant increments in capacity. Such ambitious redesign of classic wireless systems will require simultaneous innovation in multiple fields, including the signals in the physical layer and the wireless network architectures and behaviors. This project follows a cross-layer interdisciplinary approach with collaboration between two excellent research groups that contribute complementary expertise: The Wireless System Group at Stanford University (communications), and the SIGNET group at University of Padova (networks). The main research objectives of this action are 1. To study the fundamental properties of the relation between a wireless network capacity, its architecture and increased bandwidth, antenna dimensions and density. 2. To bridge the gap between the physical and network layers on this research field. 3. To design wireless network architectures that maximize the potential benefit of increased resources. 4. To develop optimal resource allocation schemes that maximize network performance in these architectures. 4. To create simulation and demonstration tools that verify the results and ease transfer of solutions to industry.'";244269;244269;H2020-MSCA-IF-2015;/MSCA-IF-GF;UNIVERSITA DEGLI STUDI DI PADOVA;IT;;;;1;0;0;1;0;0 203541;712921;Lumiblast;SIGNED;H2020-EU.1.2.1.;FETOPEN-RIA-2014-2015;H2020;A paradigm shift in cancer therapy – using mitochondria-powered chemiluminescence to non-invasively treat inaccessible tumours;2016-10-01;2021-03-31;;"Brain cancers such as glioblastoma multiforme (GBM) are practically incurable due to their location, invasiveness and highly aggressive nature. The use of light-based treatments of GBM by activating tumor-localized photosensitizers, such as in photodynamic therapy (PDT) has been clinically evaluated, but with limited success. This is mainly due to the limited penetration of light into tissue and the efficient spread of tumor cells typically up to at least 2 cm from the resection margin. Moreover, the existing photon based treatments (photodynamic therapy) are highly invasive and usually require open-cranium surgery, due to the need for external light sources. In the Lumiblast project the photons are produced inside the tumor cells in the form of chemiluminescence avoiding the major limitation of using external light to treat solid, deep-sited and inaccessible tumors. The principle utilized in Lumiblast may also be relevant for cancers of other origins. Due to its nature Lumiblast is expected to act on individual cells, rather than the collective lesion; it could thus completely eliminate the hitherto incurable GBM. Each GBM cell is expected to become a small lamp providing the light required for the photosensitive agents to become activated, killing the tumour cells from the inside. Lumiblast requires a concerted interdisciplinary action. The project coordinator (Berg’s group, Oslo University Hospital, OUS) is world renowned in PDT and photomedicine, while the team from the University of Athens (Georgios Vougioukalakis’ group, UoA) is up and coming with high expertise in synthetic chemistry. The Polytechnic University of Valencia (Miguel Miranda’s group, UPV) team is headed by a world leader in Photochemistry, the University of Oslo partner (Hanne H. T?nnensen’s group, UiO) is specialized in pharmaceutical formulation, and Knight Scientific Ltd (KSL, CEO Jan Knight) is an SME with an impressive track record in ROS-activated luminescence. This 4.5-year project will establish the Lumiblast breakthrough technology by providing proof-of-concept in extracellular systems, GBM cell cultures and animal models, with the vision to advance Lumiblast to the clinic 5-6 years after the end of the proposed project.";3031375;3031375;H2020-FETOPEN-2014-2015-RIA;/RIA;OSLO UNIVERSITETSSYKEHUS HF;NO;"ETHNIKO KAI KAPODISTRIAKO PANEPISTIMIO ATHINON;KNIGHT SCIENTIFIC LIMITED;UNIVERSITETET I OSLO;UNIVERSITAT POLITECNICA DE VALENCIA";"EL;UK;NO;ES";;1;0;0;1;0;0 204798;693229;ARCHES;SIGNED;H2020-EU.3.6.3.;REFLECTIVE-6-2015;H2020;Accessible Resources for Cultural Heritage EcoSystems;2016-10-01;2019-12-31;;"The popularisation of digitisation techniques has boosted the generation of digital cultural heritage assets in recent years. However, such techniques should not be regarded as an end in and of themselves, but as a means for enabling European citizens to engage with cultural heritage more closely and in different ways. ARCHES aims to create more inclusive cultural environments particularly for those with differences and difficulties associated with perception, memory, cognition and communication. It will achieve this through in-depth research analysis and the development of innovative applications, functionalities and experiences based on the reuse and redevelopment of the aforementioned digital resources. Our participatory research methodology situates real user needs at the heart of an iterative design and implementation process, through their active involvement in 3 pilot exercises. This will also facilitate the validation of potential solutions in scenarios at 6 museums, as well as engagement with broader audiences (e.g. children, the elderly, and other potentially marginalised groups) and extension to other sectors, mainly education and tourism. The online accessible software platform, applications for handheld devices and multisensory activities will form the basis of a technical approach that will exploit state of the art technologies – e.g. augmented reality, avatars, relief printers and models, context-sensitive tactile audio guides, metadata and advanced image processing techniques – to underpin the generation of a dynamic ecosystem. In this framework, museums will play an important role by adapting content and reinterpreting cultural heritage in manners most suitable for target groups. Our interdisciplinary consortium – involving academia, SMEs, research centres and museums – will focus on ensuring widespread communication and exploitation, stimulating cross-border collaboration to address a challenge common across Europe.";3838158,03;3399248,88;H2020-REFLECTIVE-6-2015;/IA;VRVIS ZENTRUM FUR VIRTUAL REALITY UND VISUALISIERUNG FORSCHUNGS-GMBH;AT;"NEUMULLER MORITZ;COPRIX MEDIA DOO BEOGRAD-STARI GRAD;FUNDACION LAZARO GALDIANO;UNIVERSITY OF BATH;VICTORIA AND ALBERT MUSEUM;CENTRO REGIONAL DE BELLAS ARTES DE OVIEDO;Sign time GmbH;KHM-MUSEUMSVERBAND;TREELOGIC TELEMATICA Y LOGICA RACIONAL PARA LA EMPRESA EUROPEA SL;THE WALLACE COLLECTION;FUNDACION COLECCION THYSSEN-BORNEMISZA;THE OPEN UNIVERSITY";"AT;RS;ES;UK";;1;0;0;1;0;0 202839;703613;DSMM;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;“(De) Securitising Muslims in Cyber space: Social Media, Civil society and Marginalisation After Charlie Hebdo and the Islamic State”;2016-10-01;2018-09-30;;DSMM proposes a two-year fellowship at the CNRS in Aix-en-Provence, France, with a six month secondment at the School of Oriental and African Studies in London, UK. Europe faces one of the most significant security issues of recent years in the threats posed by Islamist terrorism. Prominent in this, and little researched, is the role of social media in this process. The project aims to fill this gap by applying cutting-edge research in a vital field for the future of Europe in assessing the effect of social media narratives on the (de) securitisation of Muslims in France and the UK. It does this through taking an original and interdisciplinary approach, incorporating quantitative and qualitative methods and concepts from sociology, political science and media studies. The key research objective is to create an analytical account of the means by which social media narratives work to construct and deconstruct Muslims in France and the UK as security threats. This account draws on data from a range of social media platforms, in addition to interviews of key actors in France and the UK. In terms of outputs, the project will generate 3 peer reviewed articles. In addition, the work will be presented at international conferences and will feature in blog posts and policy briefs.;173076;173076;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FR;;;;1;0;0;1;0;0 201683;713485;INdAM-DP-COFUND-2015;SIGNED;H2020-EU.1.3.4.;MSCA-COFUND-2015-DP;H2020;INdAM Doctoral Programme in Mathematics and/or applications cofunded by Marie Sklodowska-Curie actions;2017-02-01;2022-01-31;;"The Istituto Nazionale di Alta Matematica (acronym: INdAM) is a research institution created by the Italian law, which has already been promoted two Cofund Programmes funded under FP7-PEOPLE-COFUND. The INdAM-DP-COFUND-2015 Programme plans to set up a new Doctoral Programme in order to extend the range to incoming early stage researchers who intend obtain a PhD degree in Italy. The programme creates a large network of PhD schools in mathematics and/or applications and of non-academic partners, offering to the fellows a large and free choice of research topics, PhD projects, excellent research teams, transferable skills training, international, intersectoral, and interdisciplinary training. The Programme aims to reinforce the scientific excellence, the international dimension and the scientific attractiveness of Italy, by encouraging incoming excellent early stage researchers in mathematics and/or applications to obtain a PhD in Italy.The Programme consists of two Calls; its duration is 60 months; the total number of fellowship: 20; the total number of fellows-years: 60.";3139200;1569600;H2020-MSCA-COFUND-2015;/MSCA-COFUND-DP;"""Istituto Nazionale di Alta Matematica """"Francesco Severi""""""";IT;;;;1;0;0;1;0;0 199935;691037;QUEST;SIGNED;H2020-EU.1.3.3.;MSCA-RISE-2015;H2020;QUantitative paleoEnvironments from SpeleoThems;2016-01-01;2019-12-31;;"Speleothems (cave deposits, e.g. stalagmites) represent unique terrestrial archives that allow for accurately dated, high-resolution (often annual), continuous and long (many millennia) climate reconstructions. Such records are vital for understanding how climate varies and how our environments respond on seasonal to millennial timescales. However, current speleothem studies can only make qualitative inferences about climate parameters – i.e. they can tell us the direction of change (warmer, drier, etc.) but not the amount of change (how warm? how dry?). Quantitative information is crucial to make speleothem-based data more useful to climate modellers and policy makers. QUEST (QUantitative palaeoEnvironments from SpeleoThems) will develop new techniques for extracting quantitative information from speleothems and link field and laboratory experiments on water/mineral chemistry with innovative physical and numerical analyses on speleothems. The combination of these techniques, based on physical and chemical properties and statistical methods, will allow us to deliver quantitative reconstructions of two key parameters: hydrology and temperature. We will test our methods using speleothems from Australasia, a region vulnerable to El Ni?o-Southern Oscillation (ENSO) variability. At present, there is a relative dearth of millennial-scale palaeoclimate data from this region. Our team members come from a variety of backgrounds including environmental chemistry, environmental mineral magnetism, and numerical data analysis. Each group within the team has already begun developing innovative methods for palaeoclimate reconstruction within their own subfield, but this project will be the first time these methods are combined and applied collectively to speleothems. Our combination of interdisciplinary expertise, state-of-the-art instrumentation, and novel techniques means that we are ideally placed to develop quantitative climate records from speleothems.";229500;144000;H2020-MSCA-RISE-2015;/MSCA-RISE;THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;UK;"JOHANNES GUTENBERG-UNIVERSITAT MAINZ;POTSDAM INSTITUT FUER KLIMAFOLGENFORSCHUNG;RUHR-UNIVERSITAET BOCHUM";DE;;1;0;0;1;0;0 199940;691119;EU4HIVCURE;SIGNED;H2020-EU.1.3.3.;MSCA-RISE-2015;H2020;Accelerating HIV Cure in Europe;2016-02-01;2020-01-31;;"Finding a CURE for 35 Million individuals living with HIV/AIDS is one of the great global health challenges of the 21st century. The major obstacle to HIV eradication is the persistence of latent HIV cellular reservoirs, where the integrated viral genome is transcriptionally silenced but replication-competent and can escape both Anti-Retroviral Therapy and Immune Responses. The development of novel strategies aimed at eliminating these reservoirs have become paramount in HIV research, if we want to achieve an HIV/AIDS CURE. To accelerate the State of the Art in HIV CURE research in Europe, our EU4HIVCURE consortium brings together an intersectoral and interdisciplinary collaboration between 3 Universities, 3 Hospitals, 1 International Research Organisation from 4 European countries and 1 University from Canada. Our aim is to dissect the intricate mechanisms controlling HIV-1 latency and identify new druggable targets to develop novel latency-reversing strategies and eradicate persistent viral reservoirs by forcing HIV-1 gene expression. To facilitate continuum for translation to the clinic, we have developed an operational framework, which maximises exchange of knowledge and expertise via secondements, networking and training activities.";328500;310500;H2020-MSCA-RISE-2015;/MSCA-RISE;UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN;IE;"INTERNATIONAL CENTRE FOR GENETIC ENGINEERING AND BIOTECHNOLOGY;ASSOCIATION HOSPITALIERE DE BRUXELLES-CENTRE HOSPITALIER UNIVERSITAIRE SAINT PIERRE;UNIVERSITE DE STRASBOURG;UNIVERSITE LIBRE DE BRUXELLES;MATER MISERICORDIAE UNIVERSITY HOSPITAL";"IT;BE;FR;IE";;1;0;0;1;0;0 200754;680242;BARCODE DIAGNOSTICS;SIGNED;H2020-EU.1.1.;ERC-StG-2015;H2020;Next-Generation Personalized Diagnostic Nanotechnologies for Predicting Response to Cancer Medicine;2016-04-01;2021-03-31;;"Cancer is the leading cause of death in the Western world and the second cause of death worldwide. Despite advances in medical research, 30% of cancer patients are prescribed a medication the tumor does not respond to, or, alternatively, drugs that induce adverse side effects patients' cannot tolerate. Nanotechnologies are becoming impactful therapeutic tools, granting tissue-targeting and cellular precision that cannot be attained using systems of larger scale. In this proposal, I plan to expand far beyond the state-of-the-art and develop a conceptually new approach in which diagnostic nanoparticles are designed to retrieve drug-sensitivity information from malignant tissue inside the body. The ultimate goal of this program is to be able to predict, ahead of time, which treatment will be best for each cancer patient – an emerging field called personalized medicine. This interdisciplinary research program will expand our understandings and capabilities in nanotechnology, cancer biology and medicine. To achieve this goal, I will engineer novel nanotechnologies that autonomously maneuver, target and diagnose the various cells that compose the tumor microenvironment and its disseminated metastasis. Each nanometric system will contain a miniscule amount of a biologically-active agent, and will serve as a nano lab for testing the activity of the agents inside the tumor cells. To distinguish between system to system, and to grant single-cell sensitivity in vivo, nanoparticles will be barcoded with unique DNA fragments. We will enable nanoparticle' deep tissue penetration into primary tumors and metastatic microenvironments using enzyme-loaded particles, and study how different agents, including small-molecule drugs, proteins and RNA, interact with the malignant and stromal cells that compose the cancerous microenvironments. Finally, we will demonstrate the ability of barcoded nanoparticles to predict adverse, life-threatening, side effects, in a personalized manner.";1499250;1499250;ERC-2015-STG;/ERC-STG;TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY;IL;;;;1;0;0;1;0;0 198275;675132;MASSTRPLAN;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2015-ETN;H2020;MASS Spectrometry TRaining network for Protein Lipid adduct ANalysis;2015-10-01;2019-09-30;;"MASSTRPLAN will train the next generation of interdisciplinary research leaders in advanced molecular analytical techniques to detect oxidized phospholipids & proteins in biological & clinical samples, evaluate their biochemical roles in inflammation, and translate these findings to develop new diagnostic tools. Chronic inflammatory diseases such as diabetes, cardiovascular disease (CVD) & cancer are major causes of mortality and cost the EU economy dearly in healthcare and lost working time; CVD alone is estimated to be responsible for 47% of deaths and to cost the EU €196 billion a year. Scientists able to develop advanced analytical tools for detecting oxidative biomolecule modifications and assessing their contribution to cell dysfunction & disease are urgently needed. The objectives of MASSTRPLAN are to 1) train early stage researchers (ESRs) in advanced and novel chromatography, mass spectrometry, and complementary techniques including microscopy and bioinformatics to detect challenging heterogeneous biomolecule modifications and determine their functional effects; 2) give ESRs a broad perspective on relevance & mechanisms of oxidative modifications in pathophysiology and biotechnology; 3) enable ESRs trained in technology development to engage effectively with the clinical sector; and 4) train ESRs in translational and development skills to produce new protocols, materials and commercializable diagnostic tools. The ETN will achieve this by bringing together 10 beneficiaries and 15 partners from academic, industrial and healthcare organizations working in analytical, bioinformatic, biological, clinical & biotech fields to provide multidisciplinary, cross-sector training. Extensive mobility, industrial secondments and network-wide training will yield a cohort of analytical scientists with the unique theoretical, technological, and entrepreneurial skill set to yield new understanding of oxidative inflammatory disorders, leading to better tools and therapies.";3545010,72;3545010,72;H2020-MSCA-ITN-2015;/MSCA-ITN-ETN;ASTON UNIVERSITY;UK;"MOLOGIC LTD;CENTRO CARDIOLOGICO MONZINO;UNIVERSITAET LEIPZIG;AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS;CENTRO HOSPITALAR E UNIVERSITARIO DE COIMBRA E.P.E.;UNIVERSIDADE DE AVEIRO;THERMO FISHER SCIENTIFIC (BREMEN) GMBH;VIB;UNIVERSITA DEGLI STUDI DI MILANO;INSTITUTO PORTUGUES DO SANGUE E DA TRANSPLANTACAO IP";"UK;IT;DE;ES;PT;BE";;1;0;0;1;0;0 198511;675448;TRAIN-ERS;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2015-ETN;H2020;Endoplasmic Reticulum Stress in Health and Disease;2015-10-01;2019-09-30;;"Endoplasmic reticulum (ER) stress is emerging as a common feature in the pathology of numerous diseases including cancer, neurodegenerative disorders, metabolic syndromes and inflammatory diseases. Thus ER stress represents a potential therapeutic intervention point to be exploited to develop novel therapies, diagnostic tools and markers for these diseases. However, exploitation is hampered by the shortage of scientists with interdisciplinary training that can navigate with ease between the academic, industrial and clinical sectors, and that have the scientific and complementary skills, together with an innovative outlook, to convert research findings into commercial and clinical applications. This proposal will bring young researchers together with world-leading academics, clinicians and industry personnel, who are united in (1) their goal of forming a network of excellence aimed at understanding the ER stress response mechanistically and quantitatively and (2) applying this understanding to identify and validate the most suitable intervention points in order to provide innovative knowledge-driven strategies for the treatment of ER stress-associated diseases. The TRAIN-ERS network will provide early stage researchers (ESRs) with high quality scientific and complementary skills training combined with international, intersectoral work experience. This will produce highly trained, innovative, creative and entrepreneurial ESRs with greatly enhanced career prospects, who will continue to advance the state of the art in the Biomedical field in their further careers, and will confidently navigate at the interface of academic, clinical and private sector research. The TRAIN-ERS research programme will provide the ESR’s with the knowledge and the cutting edge scientific and technical skills that will drive our understanding and exploitation of the ER stress response for therapeutic and diagnostic purposes.";3628756,8;3628756,8;H2020-MSCA-ITN-2015;/MSCA-ITN-ETN;NATIONAL UNIVERSITY OF IRELAND GALWAY;IE;"INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE;IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE;LUDWIG BOLTZMANN GESELLSCHAFT OSTERREICHISCHE VEREINIGUNG ZUR FORDERUNG DER WISSENSCHAFTLICHEN FORSCHUNG;JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN;OPTIMATA LTD;UNIVERSITAET STUTTGART;RANDOX TEORANTA;KATHOLIEKE UNIVERSITEIT LEUVEN;FUNDACIO INSTITUT D'INVESTIGACIO BIOMEDICA DE BELLVITGE;GOETEBORGS UNIVERSITET;ROYAL COLLEGE OF SURGEONS IN IRELAND";"FR;UK;AT;DE;IL;IE;BE;ES;SE";;1;0;0;1;0;0 196991;666003;IC-3i-PhD;SIGNED;H2020-EU.1.3.4.;MSCA-COFUND-2014-DP;H2020;Institut Curie 3-i PhD Program;2016-09-01;2021-08-31;;"The new IC-3i-PhD program of Institut Curie and its partners will produce top-level scientific knowledge by promoting basic interdisciplinary research that will be translated into novel therapeutic avenues for diagnosis and treatment. The completely re-structured, revitalized, and ambitious international “Triple i” PhD program is strengthened by trans- and inter-disciplinary and inter-sectorial research projects and will offer 35 international PhD positions. The program will teach PhD/Doctoral Program recipients to be excellent researchers of tomorrow; to perform research but also enhance innovation through research via established working relationships with private industry, and by supporting the creation of Small and Medium-sized Enterprises (SMEs). The objective of the doctoral programme is to offer an international, inter-disciplinary, and inter-sectorial training program for the researchers, including training-through-research (both on site and through secondments) as well as hands-on training in transferable skills. Furthermore, supporting researchers’ career development via a structured career plan, and a commitment to providing fellows with the transferable skills they need, will change the standard of excellence for PhDs at the institute, and beyond. Training IC-3i-PhDs to the high standard set out in the program will ultimately lead to producing a new generation of researchers and researcher-physicians working side by side on improving health outcomes, reducing health inequalities, and promoting active and healthy ageing. Overall the proposed project will further stimulate the development of European research and human resource capacities, knowledge transfer between academic institutions and industrial stakeholders and thus strengthen the competitiveness and innovation of EU industries.";5493600;2746800;H2020-MSCA-COFUND-2014;/MSCA-COFUND-DP;INSTITUT CURIE;FR;;;;1;0;0;1;0;0 196898;654609;germcells;CLOSED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;A platform for the generation of human gametes in vitro;2016-03-01;2018-02-28;;According to the World Health Organization, infertility is a medical condition that affects up to 14% of couples under reproductive age. The increase in infertility has led to the exponential rise in the use of assisted reproduction as a route for conceiving a baby, currently representing 1.5% of children born in Europe. Although multiple factors may contribute to infertility, the limited availability of human gametes for its study restricts the capacity of researchers in establishing the causes of this decline. To address this limitation, a talented Fellow with background in physiology of reproduction will join a leading laboratory in developmental biology to conduct multidisciplinary research aimed at developing a platform for the generation of human gametes in the laboratory. A combination of state-of-the-art tools in genomics and cell biology will be used to gain new understanding of how gamete precursors form in vivo, and this knowledge will be used to develop culture systems to generate gametes in vitro. These approaches will equip the Fellow with comprehensive new skills essential for fulfilling these objectives. The transfer of knowledge builds on the host’s expertise in animal biotechnology, the provision of interdisciplinary training in human stem cell differentiation by collaborators, and on the Fellow’s knowledge of reproductive biology. The output of the project will address key societal challenges for the EU in the areas of Health, demographic change and well-being and will contribute to the expansion of the network of experts in biotechnology.;183454,8;183454,8;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;THE UNIVERSITY OF NOTTINGHAM;UK;;;;1;0;0;1;0;0 195114;655475;JELLYPACTS;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Assessment of Jellyfish Socioeconomic Impacts in the Mediterranean: Implications for Management;2016-09-01;2020-08-30;;"Social and scientific concern about jellyfish (JF) blooms has risen over the past decades. This concern is reflected on the number of reports on JF; since 1941 the number of scientific publications on JF has doubled each decade, whilst news reports have increased by over 500% over the past two decades. Aggregations of JF can cause multitude of problems for different sectors of society; including the fishing industry and tourism. There is no doubt that the combination of a growing human population and the increasing use of the marine environment will lead to higher encounter rates between JF and humans. To add to the concern, there has been a heated scientific debate on whether JF populations might be on the rise. However, regardless of whether JF populations are increasing, there are no easy solutions to manage all the problems associated with JF blooms. Therefore, there is an urgent need to focus research objectives towards understanding the potential of a suite of management strategies to tackle current impacts of JF over ecosystem services. There are many existing strategies for managing JF blooms however, these are mostly economically expensive and thus, there is a need to evaluate whether the costs of implementing particular management policies will offset the costs of JF impacts. In order to device cost-effective management strategies, a focus on the interdisciplinary nature of JF impacts that includes ecological, social and economic aspects such as the associated loss of people’s wellbeing is of critical importance. Unfortunately, there is a knowledge gap on the socioeconomic impacts of JF and estimates are sparse and qualitative. The project proposed here has the overall goal to further the knowledge of the existing interactions between jellyfish and society by assessing the economic and social impacts stemming from their presence and the integration of this newfound knowledge into adaptive management policies.";170121,6;170121,6;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS;ES;;;;1;0;0;1;0;0 195663;658742;CONTESTED URBANISM;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Contested Cities Revisited: a multidisciplinary, multi-scale analysis of urban space;2015-04-01;2017-03-31;;"'The proposed project’s meta-objectives are twofold, first; from a theoretical perspective the starting point of the project is the suggestion that rather than limiting the 'extreme divided’ city label to a selected number of contested places, there is an increasing need to broaden the category itself in order to deepen the understanding of contested urbanism across the spectrum. Secondly, to construct an innovative interdisciplinary research method connecting the long overdue qualitative and quantitative divide within urban segregation research (Vertovec 2006). Within this discussion, there is a still significant lacuna as to how researchers and policymakers themselves conceptualize and prioritize the socially and politically contentious issues of urban segregation in different cities and the impact of urban space on social outcomes (Vaughan 2007). This research project suggests there is a need to re-think labels and concepts attributed to cities and neighborhoods, to better adapt planning policy and practice to ethnic minorities and migrants in an ever more fractured urban reality. Following a broad assessment of 'urban segregation' the research will focus on two nations with diverse forms of contested urbanism with the aim of 'learning through differences, rather than seeking out similarities' (Robinson 2011); namely Sweden (known for its comprehensive welfare system) and Israel (known for its ethnically based policies); selecting four case study cities (two from each country) with high levels of ethnic minorities for further in-depth analysis. With the aim of establishing a multi-level multidisciplinary comparative framework (engaging spatial and qualitative analysis); the project will integrate three main scales of investigation: (1) the nation state role in planning for urban segregation, (2) urban segregation at the city scale, and (3) the role of local community and civil society in, and their perception of, these urban processes. '";195454,8;195454,8;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;UNIVERSITY COLLEGE LONDON;UK;;;;1;0;0;1;0;0 195695;658988;PS-IRAQ;CLOSED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Performing a State: State-building in Iraq (2003-2006).;2016-04-01;2020-03-30;;"PS-IRAQ’s objectives: 1) study the relationship between knowledge production and political engineering in state and nation-building of occupied Iraq (2003-6); and 2) analyze how scientific knowledge of the state acted as a constituent element of political agency. This project also seeks to 3) develop detailed analysis of 2 sites of state and nation-building in Iraq (2003-6). The cases are the occupation’s and US efforts in: 1) restoring electrical supply and rebuilding the national electrical grid; and 2) the introduction of new Iraqi representative bodies. This project is interdisciplinary, drawing on comparative politics, the anthropology of state and economy, political geography, and social studies of science and technology. It examines how scholars from history, political science, political economy, anthropology and social theory have understood Iraq prior to and after the invasion, and how they engaged in the making and the transfer of ideas about the state. Data-collection relies on archival, library-based research, and interviews. The project generates conceptual and empirical insights relevant to European external action in Southern and Eastern Mediterranean Countries, especially crisis response and state-building. European excellence and innovation is promoted by developing a reflexive understanding of the relationship between social science knowledge and state-building practice and policy. Lessons from the US experience enhance the mutual understanding of US policy formation and social scientific knowledge formation processes. This will enhance potential for European international cooperation on state-building.";172800;172800;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;UNIVERSITEIT GENT;BE;;;;1;0;0;1;0;0 199032;686841;MAGNEURON;SIGNED;H2020-EU.1.2.1.;FETOPEN-RIA-2014-2015;H2020;Hijacking cell signalling pathways with magnetic nanoactuators for remote-controlled stemcell therapies of neurodegenerative disorders;2016-01-01;2019-12-31;;"Neurodegenerative diseases, such as Parkinson’s disease, are a major public health issue given the aging population in Europe and beyond. While curative pharmacological treatment of these diseases is not in sight, cell replacement therapies (CTs) are considered very promising, in particular with the advent of stem-cell reprogramming technologies. However, a fundamental challenge in the medical application of CTs in the brain of patients lies in the lack of control of cell behaviour at the site of transplantation, and particularly their differentiation and oriented growth. The aim of this project is to introduce a fundamentally new concept for remote control of cellular functions by means of magnetic manipulation. The technology is based on magnetic nanoparticles functionalized with proteins involved in cellular signalling cascades. These biofunctionalized MNPs (bMNPs) will be delivered into target cells, where they act as intracellular signalling platforms activatable in a spatially and temporally controlled manner by external magnetic fields. The project will focus on engineering these tools for the control of neuronal cell programming and fibre outgrowth by hijacking Wnt and neurotrophin signalling, respectively, with the ulti-mate objective of advancing cell replacement therapies for PD using dopaminergic precursor neurons. To achieve this ambitious goal, we have gathered an interdisciplinary consortium interfacing scientists having cutting-edge know-how in bMNP engineering, surface functionalization and cellular nanobiophysics with renowned experts in neuronal cell differentiation, stem-cell reprogramming and regenerative (nano-)medicine. By exploiting this complementary expertise, a novel, versatile technology for magnetic control of intracellular signalling is envis-aged, which will be a breakthrough for remote actuation of cellular functions and its successful implementation in CTs for neurodegenerative diseases and injuries within the following decade.";3473026;3473026;H2020-FETOPEN-2014-2015-RIA;/RIA;INSTITUT CURIE;FR;"UNIVERSITY OF KEELE;EFFICIENT INNOVATION SAS;RUHR-UNIVERSITAET BOCHUM;UNIVERSITAET OSNABRUECK;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS";"UK;FR;DE";;1;0;0;1;0;0 195489;657621;EI-USAXS;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Imaging ultra-small angle x-ray scattering with edge-illumination: exploiting sub-pixel information in medical diagnostics, materials science and security screening;2015-06-01;2017-05-31;;"The capability to image the microscopic features of a sample with an imaging system with much coarser resolution opens tantalizing opportunities to all applications of x-ray imaging. First and foremost, it can reveal features that are currently inaccessible: coupled with e.g. a widely available x-ray microscope with a resolution of a few microns, it can reveal information on nanoscale details. However, one can also envisage a use of the same capability to maintain a given, required level of resolution while using much larger pixels, which could allow lower dose in medical imaging, faster scans in industrial or security inspections, cheaper imaging system or any combination of the above. The method to image the Ultra-Small Angle X-ray Scattering (USAXS) distribution developed by the Experienced Researcher (ER) of this application enables exactly this tantalizing feature. It was developed as an additional, advanced feature of phase-based “dark field” imaging methods enabled by e.g. grating interferometry (GI), and was the subject of two recent Phys. Rev. Letters. GI is a phenomenal new phase imaging approach but has limitations in terms of transferability to systems that could be used clinically or by industry. Since real-world implementations of his method are the ER’s key objective, he has identified in edge illumination (EI) phase contrast imaging, developed by the supervisor of this project, the tool that would enable the development of a prototype making the ER’s USAXS imaging method widely available. This project will develop this prototype and test it on significant samples in medicine, material science and industrial and security scanning in direct collaboration with the end users. It will complement the ER’s skills on the development of benchtop imaging systems and significantly enlarge the range of his interdisciplinary skills and collaborations. At the same time, it will enrich the host group by providing access to a new imaging method with huge potential.";183454,8;183454,8;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;UNIVERSITY COLLEGE LONDON;UK;;;;1;0;0;1;0;0 194352;645665;GEO-RAMP;SIGNED;H2020-EU.1.3.3.;MSCA-RISE-2014;H2020;Geohazards: Risk Assessment, Mitigation and Prevention;2015-04-01;2019-03-31;;"This proposal aims to provide a step change in terms of our capacity to assess and predict risks due to geohazards (landslides and rock slides, earthquakes, floods). This is necessary in order to make built environments and infrastructures resilient to the increasing threat of natural hazards due to the expanding size of European cities and urban centres, increased use of infrastructure, and the effect of increased climatic variations. To achieve this we will bring together the complementary expertise of world leading academic groups in geotechnical, geoenvironmental and seismic engineering, soil and rock mechanics, seismology, hydrology, geology together with private engineering software companies. The goals of this proposal are: i) to investigate the key physical-mechanical aspects of major geohazards (landslides, earthquakes, floods) with a multi-disciplinary approach in order to bridge the current gaps in knowledge and enable a step-change in the current capabilities of risk assessment, prevention, and mitigation; ii) to generate new approaches to predicting geohazards by creating an international, interdisciplinary and intersectoral group which will combine existing knowledge to generate new research methodologies and applications by enabling knowledge exchange among researchers with expertise in complementary research fields; iii) to train several Early Stage Researches (ESRs) during their stay at the host Institution who will form the next generation of researchers for academic and industrial applications; iv) to improve the current normative standards and codes ruling geohazard prevention; v) to provide a competitive edge to European engineering software companies modelling geohazards.";2146500;1804500;H2020-MSCA-RISE-2014;/MSCA-RISE;UNIVERSITY OF NEWCASTLE UPON TYNE;UK;"INSTITUT POLYTECHNIQUE DE GRENOBLE;ITASCA CONSULTANTS;ITASCA CONSULTING LTD;UNIVERSITE GRENOBLE ALPES;UNIVERSITAT POLITECNICA DE CATALUNYA;UNIVERSITAET FUER BODENKULTUR WIEN;THE UNIVERSITY OF WARWICK";"FR;UK;ES;AT";;1;0;0;1;0;0 194892;653706;iNEXT;SIGNED;H2020-EU.1.4.1.2.;INFRAIA-1-2014-2015;H2020;Infrastructure for NMR, EM and X-rays for translational research;2015-09-01;2019-08-31;;"Structural biology provides insight into the molecular architecture of cells up to atomic resolution, revealing the biological mechanisms that are fundamental to life. It is thus key to many innovations in chemistry, biotechnology and medicine such as engineered enzymes, new potent drugs, innovative vaccines and novel biomaterials. iNEXT (infrastructure for NMR, EM and X-rays for Translational research) will provide high-end structural biology instrumentation and expertise, facilitating expert and non-expert European users to translate their fundamental research into biomedical and biotechnological applications. iNEXT brings together leading European structural biology facilities under one interdisciplinary organizational umbrella and includes synchrotron sites for X-rays, NMR centers with ultra-high field instruments, and, for the first time, advanced electron microscopy and light imaging facilities. Together with key partners in biological and biomedical institutions, partners focusing on training and dissemination activities, and ESFRI projects (Instruct, Euro-BioImaging, EU-OPENSCREEN and future neutron-provider ESS), iNEXT forms an inclusive European network of world class. iNEXT joint research projects (fragment screening for drug development, membrane protein structure, and multimodal cellular imaging) and networking, training and transnational access activities will be important for SMEs, established industries and academics alike. In particular, iNEXT will provide novel access modes to attract new and non-expert users, which are often hindered from engaging in structural biology projects through lack of instrumentation and expertise: a Structural Audit procedure, whereby a sample is assessed for its suitability for structural studies; Enhanced Project Support, allowing users to get expert help in an iNEXT facility; and High-End Data Collection, enabling experienced users to take full benefit of the iNEXT state-of-the-art equipment.";9999534,25;9999534,25;H2020-INFRAIA-2014-2015;/RIA;UNIVERSITEIT UTRECHT;NL;"ACADEMISCH ZIEKENHUIS LEIDEN;AARHUS UNIVERSITET;UNIVERSITEIT LEIDEN;SYNCHROTRON SOLEIL SOCIETE CIVILE;Masarykova univerzita;LUNDS UNIVERSITET;OULUN YLIOPISTO;WEIZMANN INSTITUTE OF SCIENCE LTD;EUROPEAN MOLECULAR BIOLOGY LABORATORY;FORSCHUNGSVERBUND BERLIN EV;EUROPEAN SYNCHROTRON RADIATION FACILITY;AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS;UNIVERSIDADE NOVA DE LISBOA;CONSORZIO INTERUNIVERSITARIO RISONANZE MAGNETICHE DI METALLO PROTEINE;STICHTING HET NEDERLANDS KANKER INSTITUUT-ANTONI VAN LEEUWENHOEK ZIEKENHUIS;EOTVOS LORAND TUDOMANYEGYETEM;DIAMOND LIGHT SOURCE LIMITED;JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN;EUROPEAN SPALLATION SOURCE ERIC;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;EUROPEAN SPALLATION SOURCE ESS AB;INSTITUTO DE TECNOLOGIA QUIMICA E BIOLOGICA - UNIVERSIDADE NOVA DE LISBOA;PANEPISTIMIO PATRON;INSTRUCT ACADEMIC SERVICES LIMITED";"NL;DK;FR;CZ;SE;FI;IL;DE;ES;PT;IT;HU;UK;EL";;1;0;0;1;0;0 194353;645662;SMARCOAT;SIGNED;H2020-EU.1.3.3.;MSCA-RISE-2014;H2020;Development of Smart Nano and Microcapsulated Sensing Coatings for improving of Material Durability/Performance;2015-01-01;2018-12-31;;"The proposal aims to develop an innovative approach to impart sensing functionality and detect substrate degradation. The degradation processes targeted will be corrosion of metallic substrates and mechanical damage by impact on fibre reinforced plastics and composites (FRP), used as structural components in the vehicle industry worldwide. The innovative sensing materials are based on controlled release of active species, encapsulated in polymeric and inorganic capsules with sizes ranging from several micrometres down to the nanometre range. These will be designed and prepared in a way that responds to specific triggers associated with the nature of the degradation process. The functional materials will be subsequently incorporated as additives in organic and hybrid organic-inorganic coating matrices, or directly impregnated in the substrate (FRP). The goal is to get coatings capable of sensing substrate degradation at early stages, making maintenance operations cost-effective without jeopardizing safety. The range of selected materials encloses systems conceptually designed to be prepared and tested for the first time at lab scale (high breakthrough at research level) and others already studied at lab scale with promising results and which can already be tested at pilot scale (high innovation level). Furthermore, the characterization encompasses lab-scale, cutting-edge technologies and modelling, as well as upscaling and industrial validation. The consortium upon which the present proposal is set has strong knowledge and previous experience in the topics above presented, reflected upon previous participation in large FP7 EU-projects as well as on Marie Curie actions (IRSES). Therefore, part of the interdisciplinary exchanging network necessary to successfully achieve the objectives and allow a flow and sharing environment of people, knowledge and methods has already been tested in previous projects with positive results.";900000;900000;H2020-MSCA-RISE-2014;/MSCA-RISE;UNIVERSIDADE DE AVEIRO;PT;"SMALLMATEK - SMALL MATERIALS AND TECHNOLOGIES LDA;SYNPO AKCIOVA SPOLECNOST;HELMHOLTZ-ZENTRUM GEESTHACHT ZENTRUM FUR MATERIAL- UND KUSTENFORSCHUNG GMBH;LATVIJAS UNIVERSITATES POLIMERU MEHANIKAS INSTITUTS;LATVIJAS UNIVERSITATE";"PT;CZ;DE;LV";;1;0;0;1;0;0 194339;645634;INEXCA;SIGNED;H2020-EU.1.3.3.;MSCA-RISE-2014;H2020;Excellent research and expertise of quality of cancer care by internationally trained staff;2015-03-01;2019-02-28;;"There is an international imperative to improve healthcare through health service research, including nursing research and new innovations. This EU-RISE project “Excellent research and expertise of quality of cancer care by internationally trained staff (INEXCA)” aims to utilize expertise across the globe to improve research, researcher training and care of cancer patients, family caregivers and patient and public involvement through international and intersectoral collaboration and staff exchange. The ultimate objectives are to create innovative opportunities to improve research and researchers’ skills and increase knowledge transfer from research to practice and business. The participants in the project representing academic, non-academic and clinical settings as well as information technology industry and health-related business experts from Belgium, Denmark, Finland, Italy, Great Britain and United States of America have enormous and interdisciplinary competences of their specializing areas in research methodology, quality of care, cancer care, patient involvement, family care givers and information technology in academic, non-academic and clinical settings. The participating organizations will bring their best know-how through staff’s secondments, workshops, training courses, conferences, publications and other activities. An innovative ICT platform will be developed for sharing information and knowledge. In total, 34 academic and non-academic staff members will be involved in this INEXCA project for 263 months. The participants’ synergies and complementarities from different disciplines, experiences, methodological advancements as well as clinical practice will be fully in use. The planned secondments will offer the best opportunity to get the best outcomes for patients, families, EU citizens as well as researchers. Descriptors: HEALTH SERVICES, HEALTH CARE RESEARCH";913500;913500;H2020-MSCA-RISE-2014;/MSCA-RISE;ITA-SUOMEN YLIOPISTO;FI;"SENSOFTIA OY;SYDDANSK UNIVERSITET;CEREF SRL;KATHOLIEKE UNIVERSITEIT LEUVEN;UNIVERSITY OF SURREY;POHJOIS-SAVON SAIRAANHOITOPIIRIN KUNTAYHTYMA";"FI;DK;IT;BE;UK";;1;0;0;1;0;0 194337;645648;Muscle stress relief;SIGNED;H2020-EU.1.3.3.;MSCA-RISE-2014;H2020;Muscle Stress Relief: An integrated research program linking together basic research on secondary myopathies in stress states to innovative translation in applied myology.;2016-03-01;2020-02-29;;"A diverse variety of medical or lifestyle conditions lead to a progressive loss of muscle force by functionally impairing myofibril contractility and causing ultimately myofibril loss. Major underlying risk factors of chronic muscle force loss are ageing, inactive lifestyles, and unbalanced nutrition. Together, these factors are predicted to lead to an endemic incidence of muscle weakness both in the developed countries. Clinical research on the mechanisms involved requires a multidisciplinary approach covering aspects of ageing, metabolism, and on the humoral cross-talk of muscle with other key organs including heart, liver, kidney, and lung. To achieve this, six European groups with complementary expertise in inter-organ-cross-talk during stress-induced secondary myopathies will team-up with a leading team in the U.S. with expertise in the translation of muscle research into therapeutic interventions, and with one team from South Africa with cutting-edge expertise in the regulation of regenerative capacities in muscle. Importantly, four SMEs will participate in this RISE network that provide expertise in early muscle disease detection, monitoring, and the developing preventive strategies: Their knowledge on muscle disease detection at early stages and their monitoring during interventions will promote translational innovation. To implement innovation and our joint research program, both early stage and advanced researchers will be seconded from the academic eight teams to these four SMEs and vice versa. Thereby, this RISE scheme will establish a long-term collaborative University-SME driven translational innovative research program innovation in our interdisciplinary field of growing socioeconomic medical importance.";1606500;1458000;H2020-MSCA-RISE-2014;/MSCA-RISE;UNIVERSITY OF ST MARK & ST JOHN;UK;"DLD GESELLSCHAFT FUR DIAGNOSTIKA UND MEDIZINISCHE GERATE MBH;MYOMEDIX GMBH;STICHTING VU;EUROPEAN MOLECULAR BIOLOGY LABORATORY;RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG;CHRISTOS PAPADOPOULOS & SIA O.E.;KNIGHT SCIENTIFIC LIMITED;STICHTING VUMC;FONDAZIONE PER LA RICERCA BIOMEDICA AVANZATA ONLUS;THE UNIVERSITY OF LIVERPOOL;UNIVERSITAT KONSTANZ;IMMUNDIAGNOSTIK AG;PANEPISTIMIO THESSALIAS;ZENTRALINSTITUT FUER SEELISCHE GESUNDHEIT;ASSOCIATION GENETHON;TZARTOS - DIAGNOSIS & RESEARCH IN NEUROIMMUNOLOGY MEDICAL LIMITED LIABILITY COMPANY";"DE;NL;EL;UK;IT;FR";;1;0;0;1;0;0 194331;645584;PRO4VIP;SIGNED;H2020-EU.2.1.1.;ICT-35-2014;H2020;Innovative PROcurement for Visual Impaired People;2015-02-01;2016-11-30;;"Taking into account the objectives of Vision 2020, the WHO's 2006 initiative for the elimination of avoidable blindness. When globally people with low vision are increasing as a result of the ageing of the world’s population. Where low vision not only affects the independence but has significant psychosocial and economic impact on the individual, the family and society. Major consequences of vision impairment include a child’s ability to pursue education and an adult’s ability for high quality employment, risk of falls, difficulties with daily living and increased dependence. PRO4VIP project has the objectives of : (1) the creation of an European wide network of procurers (RITT, US, FVG, BFW, AQuAS); (2) the definition of a common innovation procurement roadmap in the short term and in the long term and (3) the definition of the public procurement of innovation procedure(s) that best meet(s) their needs (that could be either a Pre-Commercial Procurement (PCP) or a Public Procurement of Innovative Solutions (PPI) or both) and that in line with Vision 2020 would either support the early detection and the screening of functional low vision conditions or would support the provision for low vision services. This will be achieved through a staged process whose main steps are: (1) the identification of the shared procurement needs; (2) the analysis of the state of the art, the technologies available in the market and the existing patents; (3) the engagement in open dialogues with other procurers, end-users and suppliers; (4) the analysis of the different public procurement of innovation options; and (5) the definition of the selected procurement procedure(s). The consortium is an interdisciplinary team composed of procurers interested in the topic from different perspectives (Health, social & Assistive Technology), with entities having the expertise to support them in identifying their common needs, validate them with the end users, other procurers and the market.";607526,25;584926;H2020-ICT-2014-1;/CSA;AGENCIA DE QUALITAT I AVALUACIO SANITARIES DE CATALUNYA;ES;"ECRIN EUROPEAN CLINICAL RESEARCH INFRASTRUCTURE NETWORK;UNIVERSITA DEGLI STUDI DI SALERNO;ZENIT ZENTRUM FUR INNOVATION UND TECHNIK IN NORDRHEIN-WESTFALEN GMBH;BEDIN SARA;UCL PARTNERS LIMITED;REGIONE AUTONOMA FRIULI-VENEZIA GIULIA;FUNDACION BARCELONA MACULA FOUNDATION RESEARCH FOR VISION;BERUFSFORDERUNGSWERK DUREN GEMEINNUTZIGE GMBH ZENTRUM FUR BERUFLICHE BILDUNG BLINDER UND SEHBEHINDERETER MENSCHEN;UNION EUROPEENNE DES AVEUGLES UEAASSOCIATION;AREA DI RICERCA SCIENTIFICA E TECNOLOGICA DI TRIESTE;ISTITUTO REGIONALE RITTMEYER PER I CIECHI DI TRIESTE";"FR;IT;DE;UK;ES";;1;0;0;1;0;0 193529;637776;ALKENoNE;SIGNED;H2020-EU.1.1.;ERC-StG-2014;H2020;Algal Lipids: the Key to Earth Now and aNcient Earth;2015-04-01;2020-03-31;;Alkenones are algal lipids that have been used for decades to reconstruct quantitative past sea surface temperature. Although alkenones are being discovered in an increasing number of lake sites worldwide, only two terrestrial temperature records have been reconstructed so far. The development of this research field is limited by the lack of interdisciplinary research that combines modern biological and ecological algal research with the organic geochemical techniques needed to develop a quantitative biomarker (or molecular fossil) for past lake temperatures. More research is needed for alkenones to become a widely used tool for reconstructing past terrestrial temperature change. The early career Principal Investigator has discovered a new lake alkenone-producing species of haptophyte algae that produces alkenones in high abundances both in the environment and in laboratory cultures. This makes the new species an ideal organism for developing a culture-based temperature calibration and exploring other potential environmental controls. In this project, alkenone production will be manipulated, and monitored using state-of-the-art photobioreactors with real-time detectors for cell density, light, and temperature. The latest algal culture and isolation techniques that are used in microalgal biofuel development will be applied to developing the lake temperature proxy. The objectives will be achieved through the analysis of 90 new Canadian lakes to develop a core-top temperature calibration across a large latitudinal and temperature gradient (? latitude = 5°, ? spring surface temperature = 9°C). The results will be used to assess how regional palaeo-temperature (Uk37), palaeo-moisture (?Dwax) and palaeo-evaporation (?Dalgal) respond during times of past global warmth (e.g., Medieval Warm Period, 900-1200 AD) to find an accurate analogue for assessing future drought risk in the interior of Canada.;940883;940883;ERC-2014-STG;/ERC-STG;UNIVERSITY OF GLASGOW;UK;;;;1;0;0;1;0;0 193590;638665;EURO-LAB;SIGNED;H2020-EU.1.1.;ERC-StG-2014;H2020;Experiment to Unearth the Rheological Oceanic Lithosphere-Asthenosphere Boundary;2016-04-01;2021-03-31;;"Plate tectonics has been a fundamental tenet of Earth Science for nearly 50 years, but fundamental questions remain, such as where is the base of the plate and what makes a plate, “plate-like?” A better understanding of the transition from the rigid lithospheric plate to the weaker mantle beneath – the rheological lithosphere-asthenosphere boundary (LAB) - has important implications for the driving forces of plate tectonics, natural hazard mitigation, mantle dynamics, the evolution of the planet, and climate change. There are many proxies used to estimate the depth and nature of the base of tectonic plates, but to date no consensus has been reached. For example, temperature is known to have a strong effect on the mechanical behaviour of rocks. However, it has also been suggested that the chemical composition of the plate provides additional strength or that melt weakens the mantle beneath the plate. We are at a critical juncture where large-scale efforts using geophysical, geochemical, and geological techniques are being launched to better understand the definition of the tectonic plate. The simple and short history of the ocean plate makes it the ideal location to advance our understanding. However, imaging the oceanic LAB has proved challenging given the remoteness of the oceans and associated difficulties in instrumentation. Most observations come from only one ocean, the Pacific, from indirect, remote observations, at different areas and scales. I propose a large-scale effort to systematically image an oceanic plate beneath the Atlantic from birth at ridge to 40 My old seafloor. I will deploy ocean bottom seismometers (OBS) and magnetotelluric (MT) instruments, and I will image the plate at a range of resolution scales (laterally and in depth) and sensitivities to physical and chemical properties. This large, focused, interdisciplinary effort will finally determine the processes and properties that make a plate strong and define it.";1827855;1827855;ERC-2014-STG;/ERC-STG;UNIVERSITY OF SOUTHAMPTON;UK;;;;1;0;0;1;0;0 193340;635595;CARBAZYMES;SIGNED;H2020-EU.2.1.4.;BIOTEC-3-2014;H2020;Sustainable industrial processes based on a C-C bond-forming enzyme platform;2015-04-01;2019-03-31;;"C-C bond forming reactions are at the heart of industrial organic synthesis, but remain largely unexplored due to long development timelines and the lack of broad biocatalytic reaction platforms. CARBAZYMES addresses these challenges by assembling an interdisciplinary and intersectoral consortium as a powerful synergistic tool to promote innovation in the field of biocatalytic C-C bond formation at large scale, and thus the global competitiveness of the European chemical and pharmaceutical industry. The proposed consortium, with 50% industrial participation, represents academia but also commercial interests in different stages of the research-to-market process. This top-down approach, together with a life-cycle innovation approach ensures an industrial drive to the project. Clearly aligned with the scope of topic BIOTEC3-2014, CARBAZYMES will pursue the biocatalytic synthesis (spanning TRLs 5-7) of 4 APIs and 3 bulk chemicals –corresponding to market needs detected by the industrial partners in the Consortium. This will be accomplished through an inter-disciplinary approach which includes: i) a broad platform of 4 types of unique C-C bond-forming enzymes, mostly lyases; ii) the capacity to rapidly evolve enzymes to operate under industrial conditions by means of novel enzyme panels and massive screening methods; iii) application of microreactor technology for bioprocess characterization; iv) demonstration actions comprising technical (up to 100L) and economic viability studies carried out by industrial partners. CARBAZYMES unmistakably aims to have social and economic impact by addressing markets worth bn €, developing enzyme evolution technologies beyond the state of the art and creating qualified jobs and technical-scale facilities at the industrial partners’ sites. CARBAZYMES will also achieve an environmental impact by enforcing that the developed processes replace more energy and resource intensive processes, thus leading to reduced environmental footprints.";9251355;8202966;H2020-LEIT-BIO-2014-1;/IA;TECHNISCHE UNIVERSITAT DARMSTADT;DE;"EVONIK CREAVIS GMBH;ALBERT-LUDWIGS-UNIVERSITAET FREIBURG;TECHNISCHE UNIVERSITAET BRAUNSCHWEIG;EVONIK INDUSTRIES AG;AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS;SVEUCILISTE U ZAGREBU FAKULTET KEMIJSKOG INZENJERSTVA I TEHNOLOGIJE;PROZOMIX LIMITED;RIJKSUNIVERSITEIT GRONINGEN;UNIVERSIDAD AUTONOMA DE MADRID;SUSTAINABLE MOMENTUM SL;BIOCHEMIZE SL;ENZYMICALS AG;BIO-PRODICT BV;INSTITUT UNIV DE CIENCIA I TECNOLOGIA SA";"DE;ES;HR;UK;NL";;1;0;0;1;0;0 193178;633152;GEOFLUIDS;SIGNED;H2020-EU.1.1.;ERC-StG-2014;H2020;Geometric problems in PDEs with applications to fluid mechanics;2015-03-01;2020-02-29;;There are many high-profile problems in PDEs that ultimately boil down to assertions of a strongly geometric or topological nature. One feature that makes these problems both very difficult and extremely appealing is that there is not a standard set of techniques that one can routinely resort to in order to attack them. Indeed, the very nature of these questions makes them strongly interdisciplinary, so successful approaches require finely tailored combinations of ideas and techniques coming from different branches of mathematics (analysis, geometry and topology), often interspersed with some physical intuition. In this project I aim at going significantly beyond the state of the art in a wide class of geometric questions in PDEs, with an emphasis on problems in fluid mechanics and encompassing long-standing questions that can be traced back to leading analysts and geometers such as Arnold, De Giorgi and Yau. The project is divided in three interrelated blocks, respectively devoted to the study of Beltrami fields in steady incompressible fluids, to geometric evolution problems and to global approximation theorems. Key to the proposal is a versatile new approach to a number of geometric problems in PDEs that I have pioneered and applied in several seemingly unrelated contexts. The power of this technique is laid bare by my recent proofs of a well-known conjecture on knotted vortex lines in topological fluid mechanics that was popularized by Arnold and Moffatt in the 1960s and of a long-standing conjecture on the existence of thin vortex tubes in steady solutions to the Euler equation that dates back to Lord Kelvin in 1875. The award of a Starting Grant will enable me to establish a top-level research group on these topics.;1256375;1256375;ERC-2014-STG;/ERC-STG;AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS;ES;;;;1;0;0;1;0;0 205433;721846;ExSIDE;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2016;H2020;Expectations and Social Influence Dynamics in Economics;2017-01-01;2020-12-31;;"Expectations play a crucial role in determining the behaviour of many economic decision makers. The recent financial and economic crisis has highlighted the importance of expectation dynamics for economic development, the success of firm strategies and public policies. The Innovative Training Network ExSIDE aims at improving our understanding of the role of expectation formation and social influence for economic dynamics and for the optimal design of economic policy. This agenda will be pursued by combining an interdisciplinary research agenda with an innovative European joint doctoral training programme, which provides Early Stage Researchers with a broad range of expertise and skills needed for a thorough analysis of expectation formation processes and their role in Economics. Both the research projects and the training activities will combine work in Behavioural Economics, Psychoanalysis, Opinion Formation, Network Theory, Agent-based Simulation and Economic Modelling in different areas. The academic training will be complemented by extensive Transferable Skills Training Measures, Inter-Sectoral Training Measures, provided by non-academic partners, and Career Development Training. Interaction with stakeholders, policy makers and the general public will play an important role in pursuing the ExSIDE agenda and disseminating the results. The ExSIDE consortium consists of eight leading European universities and nine non-academic partners. Each Early Stage Researcher will be hosted by two universities, has a secondment with a non-academic partner and will graduate with a joint or double degree. The research and training in ExSIDE will ensure world-wide employability of the ExSIDE graduates inside and outside academia and will also boost the ability of European institutions and companies to develop efficient policies and strategies. ExSIDE will reinforce the establishment and long term sustainability of structured European joint doctoral programmes in Economics.";3864090,24;3864090,24;H2020-MSCA-ITN-2016;/MSCA-ITN-EJD;UNIVERSITAET BIELEFELD;DE;"UNIVERSITE CATHOLIQUE DE LOUVAIN;UNIVERSITA CA' FOSCARI VENEZIA;UNIVERSITE PARIS I PANTHEON-SORBONNE;UNIVERSITY OF SURREY;UNIVERSITA CATTOLICA DEL SACRO CUORE;UNIVERSITEIT VAN AMSTERDAM";"BE;IT;FR;UK;NL";;1;0;0;1;0;0 205418;722591;PHOTOTRAIN;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2016;H2020;ENTREPRENEURING DYNAMIC SELF-ORGANIZED INTERFACES IN PHOTOCATALYSIS: A MULTIDISCIPLINARY TRAINING NETWORK CONVERTING LIGHT INTO PRODUCTS;2016-10-01;2020-09-30;;The global need to move current human technologies into a sustainable future will have a great impact for the world of chemistry and related industries. In close concert with other disciplines, chemistry will be increasingly solicited to identify solutions that are practical, affordable and ultimately sustainable. To meet these objectives, not only research, but also chemical education will need profound reforms that have to be contextualized in the multidisciplinary and intersectoral picture of a sustainable development. It is propelled by these societal needs that, by educating and practising 14 ESRs, PHOTOTRAIN will ensure photo-triggered chemical process to play its central role in sustainability. By capitalising on the basic principles of supramolecular chemistry to program dynamic self-organized photoactive interfaces, it is intended to raise the creativity, knowledge, skills and capacity of the ESRs to conceive new ideas for reforming current industrial transformations into a new generation of “light-triggered” processes. The challenge of developing and transferring light-fuelled processes from a proof-of-principle to an exploitable process is to embark upon a dynamic configuration in which photoactive species are kept separated, act independently and are finally recycled. In particular, through the adoption of a microfluidic system in which programmed different phases allow the formation of photoactive interfaces, it is planned to implement photo-catalytic technologies at the industrial level for triggering stereoselective organocatalytic transformations (i.e., pharmaceutical applications) and/or solar fuels production. By the organisation of targeted individual projects and interdisciplinary secondements, ESRs will be guided toward attractive early-stage career opportunities as researchers, process chemists, chemical engineers and research managers in collective forms at various academic and research institutes, small and large enterprises, and NGOs.;3630212,28;3630212,28;H2020-MSCA-ITN-2016;/MSCA-ITN-ETN;ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA;IT;"FUNDACIO PRIVADA INSTITUT CATALA D'INVESTIGACIO QUIMICA;UNIVERSITA DEGLI STUDI DI TRIESTE;ELVESYS SAS;CHIROTECH TECHNOLOGY LIMITED;CONSIGLIO NAZIONALE DELLE RICERCHE;TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY;KATHOLIEKE UNIVERSITEIT LEUVEN;CARDIFF UNIVERSITY";"ES;IT;FR;UK;IL;BE";;1;0;0;1;0;0 193164;633127;UPWARDS;SIGNED;H2020-EU.2.1.6.1.;COMPET-08-2014;H2020;Understanding Planet Mars With Advanced Remote-sensing Datasets and Synergistic Studies;2015-03-01;2018-02-28;;"The goals of the UPWARDS project match the topics, challenges and scope of the Compet-8-2014 call. UPWARDS has as its overarching objective the revision and exploitation of data from the European Mars Express (MEx) mission as well as other Martian missions using a synergistic combination of state-of-the-art atmospheric/subsurface models and novel retrieval tools. UPWARDS will 1) address major open science questions which require an integrated understanding of the Mars coupled system from the subsurface to the upper atmosphere; 2) prepare for ExoMars 2016 Trace Gas Orbiter data analysis and exploitation; and 3) deliver enhanced scientific context and datasets for ExoMars 2018 Rover operations and future missions. The UPWARDS Consortium undertake five grand science themes which challenge our current understanding of the complex couplings of the Mars’ climate: 1) exchange of trace species between subsurface & atmosphere; 2) global cycle of Martian water; 3) surface properties and behaviour of suspended aerosols and dust storms; 4) drastic changes at the day/night terminator; 5) coupling of the lower and upper atmosphere and escape to space. All topics are addressed by experts in the field, exchanging results and knowledge in a truly synergistic and interdisciplinary collaboration. All topics share a common methodology and work flow: 1) compilation of new or unexploited data from MEx; 2) generation of added-value products with new/validated tools developed in the Consortium; 3) analysis and combination of the results with state-of-the-art models. Included is a novel data-assimilation devoted to supply as an end-product, the first of its-kind 4-D (x,y,z,t) database for ExoMars and beyond. The dissemination of UPWARDS high-level data products and the outreach activities by the scientists who produce them, will pave the way for establishing a long-term competency in Martian research at a global recognized level, and breed a new generation of European scientists.";2103593,75;2103593,75;H2020-COMPET-2014;/RIA;AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS;ES;"UNIVERSIDAD COMPLUTENSE DE MADRID;ISTITUTO NAZIONALE DI ASTROFISICA;KONINKLIJKE STERRENWACHT VAN BELGIE;INSTITUT ROYAL D'AERONOMIE SPATIALEDE BELGIQUE;THE OPEN UNIVERSITY;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS";"ES;IT;BE;UK;FR";;1;0;0;1;0;0 218320;823901;sosclimatewaterfront;SIGNED;H2020-EU.1.3.3.;MSCA-RISE-2018;H2020;Linking Research and Innovation on Waterfront through Technology for Excellence of Resilience to face Climate Change;2019-01-01;2021-12-31;;"sosclimatewaterfront mission is to develop affordable research environment and efficient operational tools at ULHT/LEAU and HEI partners by creating a Doctorate Consortium’s to face the effects of climate change. The aim is to make use of the existing strategic network to enhance the research carried on in the field of urban waterfronts. To face the future challenges in managing, adapting and mitigating the effect brought by the increasing number of disasters, ULHT/LEAU has been cooperating with HEI partners to produce and disseminate solutions, that enhance resilience. The research network will reinforce the dynamic partnerships and increase the quality and technologic innovations of the research, to design tools, to face the growing costs imposed by disasters. S.O.S. waterfront enables ULHT/LEAU and HEI partners to bring excellence in research to a higher level and to improve its international position. To reach excellence requires the call for (1) interdisciplinary and international research case studies, (2) steady sustainable research structure, (3) dissemination and open access of knowledge covered by different cultures, sciences and communities in each location. The organization of data of comparative cases and algorithms will be used to provide future scenarios thus reinforcing the centre of our research project. Our work methodology has been attracting the collaboration of top researchers which S.O.S. waterfront aims to gather in the exchange of knowledge and joint initiatives to produce results that are valuable to Europe and applicable worldwide. The Doctorate Consortium will build up trans-national collaborative events with local Municipalities to produce results . The measures to reach scientific innovation and excellence are implemented and verified in each step. The continuous exposure of the results produced by design research includes exhibition, publications, media and digital platforms to reach wider audiences, local and global.";782000;782000;H2020-MSCA-RISE-2018;/MSCA-RISE;COFAC COOPERATIVA DE FORMACAO E ANIMACAO CULTURAL CRL;PT;"FUNDACJA RIVER//CITIES PLATFORM;ARISTOTELIO PANEPISTIMIO THESSALONIKIS;UNIVERSITA DEGLI STUDI DI FIRENZE;URZAD MIEJSKI W GDANSKU;STICHTING CPO NOORD-HOLLAND;INESC ID - INSTITUTO DE ENGENHARIADE SISTEMAS E COMPUTADORES, INVESTIGACAO E DESENVOLVIMENTO EM LISBOA;POLITECHNIKA GDANSKA;INTERCULT PRODUCTIONS EK;ASSOCIACAO COMERCIAL DE LISBOA-CAMARA DE COMERCIO E INDUSTRIA PORTUGUESA";"PL;EL;IT;NL;PT;SE";;1;0;0;1;0;0 218554;820466;CiViQ;SIGNED;H2020-EU.1.2.3.;FETFLAG-03-2018;H2020;Continuous Variable Quantum Communications;2018-10-01;2021-09-30;;"The goal of the CiViQ project is to open a radically novel avenue towards flexible and cost-effective integration of quantum communication technologies, and in particular Continuous-Variable QKD, into emerging optical telecommunication networks. CiViQ aims at a broad technological impact based on a systematic analysis of telecom-defined user-requirements. To this end CiViQ unites for the first time a broad interdisciplinary community of 21 partners with unique breadth of experience, involving major telecoms, integrators and developers of QKD. The work targets advancing both the QKD technology itself and the emerging “software network” approach to lay the foundations of future seamless integration of both. The technological advantage will more specifically aim to: - Design architectures and implement protocol extensions of flexible “software based” networks for midterm country-wide QKD reach. - Drive CV-QKD systems and components up to TRL 6, derive standardized set of interfaces, also allowing a network-aware software defined functionality and open modular development, and pursue cost reduction by seamless integration of off-the-shelf components. - Push CV-QKD performance boundary forward by developing high-performance photonic integrated circuits (PIC) for CV-QKD, i.e. opening the way for ultra-low cost systems, and improve further the CV-QKD hallmark coexistence capability with standard WDM channels, i.e. reducing dramatically the barriers to optical network co-integration. - Prepare actively for next-generation networks by developing core enabling technologies and protocols aiming at quantum communication over global distances with minimal trust assumptions. CiViQ will culminate in a validation in true telecom network environment. Project-specific network integration and software development work will empower QKD to be used as a physical-layer-anchor securing critical infrastructures, with demonstration in QKD-extended software-defined networks.";9974006,25;9974006,25;H2020-FETFLAG-2018-03;/RIA;FUNDACIO INSTITUT DE CIENCIES FOTONIQUES;ES;"INSTITUT NATIONAL DE RECHERCHE ENINFORMATIQUE ET AUTOMATIQUE;NEXTWORKS;AIT AUSTRIAN INSTITUTE OF TECHNOLOGY GMBH;ORANGE SA;QUSIDE TECHNOLOGIES SL;FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.;HUAWEI TECHNOLOGIES DUESSELDORF GMBH;VLC PHOTONICS SOCIEDAD LIMITADA;CORIANT R&D GMBH;TELEKOM DEUTSCHLAND GMBH;UNIVERSITY OF YORK;INSTITUT MINES-TELECOM;TELEFONICA INVESTIGACION Y DESARROLLO SA;MELLANOX TECHNOLOGIES LTD - MLNX;DANMARKS TEKNISKE UNIVERSITET;UNIVERZITA PALACKEHO V OLOMOUCI;NOKIA BELL LABS FRANCE;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;UNIVERSIDAD POLITECNICA DE MADRID";"FR;IT;AT;ES;DE;UK;IL;DK;CZ";;1;0;0;1;0;0 214417;797444;CLAMOR;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;environmental Conflicts through the Lens of Artwork and Multimedia in waterscape transfORrmations;2018-09-03;2021-09-02;;"The fellowship aims at establishing the applicant as an expert in the study of environmental conflicts through training in the interdisciplinary fields of (gendered) water justice and data-intensive social science at the University of California Berkeley. I will analyse artworks produced in water-related ecological distribution conflicts (EDC) in which transformative or restorative initiatives operate under violent conditions. The use of artworks in EDC has not been theorised enough although they are crucial to elicit the valuation languages held by local populations, this being a main tenet of ecological economics, and more generally of the environmental social sciences. I will conduct empirical research on the gendered use in EDC of artistic creations (films, plastic arts and songs), connected multimedia, and supporting ICTs, at two levels: a) case studies drawing on activist knowledge of EDC over wetlands and over coal (both water-related) under diverse contexts of violence in Colombia and California; and b) databases on artworks, and on social media, from EDC in countries where there is violence against environmental defenders (e.g., Philippines and Brazil). The research and associated training will innovatively use mixed methods, combining in-depth case studies, ideal for developing causal explanations, with data-intensive social science research methods such as big-data extended ethnography, which provide grounds for generalisation. CLAMOR will address environmental justice issues that are of relevant for Europe and will build up a large database of artworks used in EDC at the global level. The action contributes to two H2020’s societal challenges and reinforces the European Innovation Partnership on Water, and the Water Justice Action Group in particular. Knowledge will be reintegrated at the Universitat Aut?noma de Barcelona through postgraduate teaching and supervision, and by establishing a distinctive line of research on arts and environmental conflicts.";257191,2;257191,2;H2020-MSCA-IF-2017;/MSCA-IF-GF;UNIVERSITAT AUTONOMA DE BARCELONA;ES;;;;1;0;0;1;0;0 216368;810729;iBioGen;SIGNED;H2020-EU.4.b.;WIDESPREAD-05-2017;H2020;Twinning for European excellence in Island Biodiversity Genomics;2018-09-01;2021-08-31;;Biodiversity genomics is transforming our understanding of biological diversity and leading to new discoveries that can limit biodiversity decline and therefore benefit human societies. Island biotas are highly vulnerable and thus require efficient conservation and sustainable development. They are also prime model systems for applied and fundamental research in organismal biology. iBioGen aims to significantly enhance the scientific and innovation performance of a Widening country (Cyprus) in biodiversity genomics, with focus on island biodiversity. As the third-largest island of the Mediterranean, Cyprus is an ideal site for island biodiversity research, but local capacity is currently lacking. iBioGen is recognising the great potential of novel DNA methodology for future island biodiversity research and the need for methodological unification and theoretical synthesis in this new field. Twinning of the University of Cyprus (UCY) with three internationally-leading partners in biodiversity genomics (NHM), island biodiversity research (CSIC) and biodiversity modelling (CNRS) will: (i) stimulate research excellence and international visibility of UCY, (ii) improve networking efficiency and interdisciplinarity, and (iii) have broad societal and environmental impact towards valuing and protecting island biodiversity. These objectives will be achieved through a set of training, networking and dissemination activities, including: staff exchanges, on-site training and an international summer school, international symposia on methodological unification and theoretical synthesis, outreach events directed towards biodiversity stakeholders and local communities. The expected impacts include an increase in scientific output and successful research proposal applications of UCY, establishment of an EU island network of Genomic Observatories, and integration of new technologies in biomonitoring and environmental policy at regional and EU level.;999320;999320;H2020-WIDESPREAD-05-2017-Twinning;/CSA;UNIVERSITY OF CYPRUS;CY;"NATURAL HISTORY MUSEUM;AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS";"UK;ES;FR";;1;0;0;1;0;0 214315;794117;aWARE;TERMINATED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;West Africa's Role in Human Evolution;2018-08-01;2020-07-31;;"Recent evidence indicates that the roots of our species, Homo sapiens, do not trace back to a single population, but to morphologically diverse group living over an extensive geographic area from Morocco to South Africa. The range of environments and regions in Africa that played a role in shaping our species is therefore rapidly emerging as central to unravelling human origins. However, thanks to the lack of fieldwork in many regions of Africa, these important parameters are not well understood. The aWARE project will therefore undertake a timely investigation into the role of Africa’s western forests, and their neighbouring ecozones, in modern human origins. Genetic and fossil studies have associated poorly known West Africa with complex evolutionary processes thought to have played a key role in shaping our species. Such processes include admixture between our species and late-surviving archaic humans, and long-term isolation of H. sapiens populations in forested zones. Significantly, research in West Africa by the applicant has also identified a unique late persistence of stone tool technology typical of much older periods, while at the same time demonstrating that human populations were present in currently forested regions close to the time of H. sapiens speciation. aWARE builds on this pilot work and sets forth a series of explicit, testable hypotheses to explore the time depth and environmental context of human populations in West Africa as a window into our pan-African origins. To adequately address these hypotheses, an interdisciplinary approach is taken, combining information from archaeology and palaeoecology. By exploring major theories in recent human origins through Africa’s poorly known western region, the project offers an opportunity to radically change our understanding of recent human evolution. The results will be broadly communicated through open access resources, including an online database and targeted public outreach activities.";171460,8;171460,8;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;DE;;;;1;0;0;1;0;0 212995;778070;TransFerr;SIGNED;H2020-EU.1.3.3.;MSCA-RISE-2017;H2020;Transition metal oxides with metastable phases: a way towards superior ferroic properties;2017-12-01;2021-11-30;;The main objective of the project is development of complex transition metal oxides with perovskite-like structure having improved and controllable (multi)ferroic properties. The mentioned materials are manganites and ferrites with optimal composition having distinct magnetization, polarization, (magneto)transport properties or magnetoelectric coupling. The idea of the project is to utilize reduced structural stability of these oxides which increases their sensitivity to external stimuli. Improved functional properties of these oxides can be controlled via modification of the chemical bond character, structural parameters, stoichiometry, defects etc. The reduced stability is associated with the metastable structural state formed in the vicinity of the phase boundaries, while this state presumably consists of coexistent nanoscale regions of the adjacent structural phases. There are two ideas to create metastable state: the first one – to design ceramics via chemical substitution and post-synthesis treatment by high pressure and/or thermal cycling in gases to induce nanoscale regions, the second one assumes chemical routes synthesis of films and ceramics. Besides the fundamental interest of the phase transitions and related phenomena affecting properties of the oxides the applicants consider them to be effective materials for electronic applications (as sensors, magnetic memory elements, filters etc.). Research of these oxides requires consolidative efforts of specialists in different scientific areas - Materials Science, Theoretical Physics, Solid State Physics etc. as well as an access to unique equipment and facilities. Another important objective of the project is a formation of interdisciplinary network of teams and specialists with different scientific backgrounds which will ensure effective transfer of actual knowledge and skills. Development of the transition metal oxides with controllable properties has promising commercial opportunities for the involved SME.;783000;783000;H2020-MSCA-RISE-2017;/MSCA-RISE;INSTYTUT NISKICH TEMPERATUR I BADAN STRUKTURALNYCH IM. WLODZIMIERZA TRZEBIATOWSKIEGO POLSKIEJ AKADEMII NAUK;PL;"HELMHOLTZ-ZENTRUM GEESTHACHT ZENTRUM FUR MATERIAL- UND KUSTENFORSCHUNG GMBH;VILNIAUS UNIVERSITETAS;UNIVERSIDADE DE AVEIRO;NANOCERAMICS SPOLKA AKCYJNA;INSTITUTE OF PHYSICS OF NATIONAL ACADEMY OF SCIENCE OF UKRAINE";"DE;LT;PT;PL;UA";;1;0;0;1;0;0 211921;767187;QuIET;SIGNED;H2020-EU.1.2.1.;FETOPEN-01-2016-2017;H2020;Quantum Interference Enhanced Thermoelectricity;2018-02-01;2021-07-31;;"Our vision is to demonstrate that room-temperature quantum interference effects, measured recently in single molecules, can be exploited in massively-parallel arrays of molecules and used to design ultra-thin-film thermoelectric devices with unprecedented ability to convert waste heat to electricity using the Seebeck effect and to cool at the nanoscale via the Peltier effect. Although the dream of high-performance thermoelectric devices has been discussed for many years, evidence of the room-temperature quantum interference effects needed to realise this dream was achieved experimentally only recently. Building on these indirect demonstrations of quantum interference in single molecules using non-scalable set ups, we anticipate that the next breakthrough will be the implementation of QI functionality these intechnologically-relevant platforms. We shall design molecules with built-in quantum interference functionality, which can be used to engineer the properties of ultra-thin molecular films. Molecules will be designed with robust anchors to metallic and carbon-based nano-gap electrodes, which enhance electron transport and eliminate unwanted phonons.This contacting strategy is scalable from a single junction, with the potential to be replicated billions of times on a single substrate. The ability to exploit quantum interference at room temperature will enable new thermoelectric materials and devices with the ability to scavenge energy with unprecedented efficiency. QuIET is a highly interdisciplinary project that brings together internationally leading scientists from four different countries with proven expertise on synthesis, transport measurements and theoretical modelling.";3118272,5;3118272,5;H2020-FETOPEN-1-2016-2017;/RIA;UNIVERSIDAD AUTONOMA DE MADRID;ES;"UNIVERSITAT BASEL;UNIVERSITY OF DURHAM;IBM RESEARCH GMBH;LANCASTER UNIVERSITY;EIDGENOSSISCHE MATERIALPRUFUNGS- UND FORSCHUNGSANSTALT;TECHNISCHE UNIVERSITEIT DELFT";"CH;UK;NL";;1;0;0;1;0;0 211237;741520;Locus Ludi;SIGNED;H2020-EU.1.1.;ERC-2016-ADG;H2020;Locus Ludi: The Cultural Fabric of Play and Games in Classical Antiquity;2017-10-01;2022-09-30;;"Play and games were ubiquitous in antiquity, among free men and slaves, men and women, adults and children, in town and country. Even gods played. Ludic culture created communities from early childhood to a ripe old age. Did these groups play together, or did they play different games, with distinct rules? And did they play similar games to us? This interdisciplinary project will provide the first comprehensive study of the evidence. Written, archaeological and iconographic sources are abundant, but forgotten in museums and libraries. This neglect is due to the modern Western view of games as children’s pastime, if not a waste of time. Ancient play and games reflect the gendered, religious, economic, and political fabric of a society, as much as they shape the lives of players by transmitting a cultural identity and an intangible heritage. Ludic culture evolves over time and this project intends to provide a benchmark by reconstructing this history in the Greek world, from the birth of the city-state, c. 800 BCE, to the Roman conquest in 146 BCE, and in the Roman world from the Republican age, c. 500 BCE, to the end of the Western Roman Empire, c. 500 CE. Locus Ludi will identify, categorize, and reconstruct games and play thanks to close linguistic, historical, archaeological, typological, topographical, iconographic, and anthropological studies. Ludic culture also mirrors interactions between different populations, as in the romanisation process, and religious shifts. The research will be informed by theoretical studies of the past as well as by gender and education studies. It will generate a new vision of the cultural fabric of ancient society, provide models for training and research in related fields, as well as up-to-date material for schools, museums, and libraries. Understanding the educational, societal and integrative role of play in the past is important to understand the present and widen the debate on high tech toys and new forms of sociability.";2495930;2495930;ERC-2016-ADG;/ERC-ADG;UNIVERSITE DE FRIBOURG;CH;;;;1;0;0;1;0;0 210602;754411;ISTplus;SIGNED;H2020-EU.1.3.4.;MSCA-COFUND-2016;H2020;ISTplus - Postdoctoral Fellowships;2017-07-01;2022-06-30;;"ISTplus offers two-year fellowships for highly qualified, incoming postdocs fulfilling the mobility criterion, who will have the chance to join our world-class research teams in the fields of Biology, Neuroscience, Mathematics, Physics, and Computer science at IST Austria. The fellows will be integrated in a truly interdisciplinary research environment, interacting closely with colleagues from different fields (through shared facilities, joint projects, and events). The international dimension will be ensured by the multinational teams (with employees from more than 50 countries) and through international networking. An open, bottom-up international recruiting process will ensure scientific quality and potential of the selected ISTplus fellows. Already at the beginning of their stay, fellows together with a Career Counselor will assess their professional profile and skill set, define the direction of their future career path (be it academic or non-academic) and elaborate a development plan, supported by our Targeted Competence Building Program. A co-supervision scheme will support the fellows during their stay, meant to oversee scientific progress, but also to give advice regards individual career planning. A secondment scheme should kick-start and facilitate cross-boundary networking and translational research with an intersectorial network of excellent partners, incl. SMEs, applied research companies, organizations in the field of tech transfer and science education, and commercial enterprises. Fellows will be supported in the choice of the right partner, in setting up a research plan, and may opt for an extension of the fellowship for up to six months to enable intersectoral mobility. Various events, workshops, trainings, and further activities in the area of tech transfer will cultivate an open-minded entrepreneurial spirit among program participants.";9180400;4590200;H2020-MSCA-COFUND-2016;/MSCA-COFUND-FP;Institute of Science and Technology Austria;AT;;;;1;0;0;1;0;0 209563;747257;PLANAFFHO;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;PLANAFFHO - PLANning for AFFordable HOusing;2018-02-01;2020-01-31;;PLANAFFHO - PLANning for AFFordable HOusing, aims to examine how land-use planning has contributed to the provision of affordable housing for low-income people and has promoted a mix of housing tenures within new developments in three capital cities - Copenhagen, Lisbon, and London, over the last ten years. The first aim and principal focus of the research is therefore investigating planning and housing activities in three cities (Copenhagen, Lisbon and London) that seek to address problems of housing shortage, affordability, and segregation of housing tenures. The research aims to provide practical knowledge and innovative advice to decision-makers on what can be done regarding these huge societal challenges. The second aim of the research, underpinning and informing the former, is to make a contribution to the theoretical and methodological advancement of international comparative research on housing and land-use planning. In order to meet these aims, the theoretical and methodological skills of the candidate will be strengthened at the Cambridge Centre for Housing and Planning Research, located within the Department of Land Economy, University of Cambridge, and led by Professor Michael Oxley. With over 25 years of experience and a proven track record of providing evidence and analysis to influence and support better policy and practice in several areas, the Centre is well-placed to broaden her practical experience of housing and planning matters, from both an interdisciplinary and a comparative perspective. The research will involve short-term visits to planning departments and non-profit housing associations in Copenhagen, Lisbon, and London, aiming to contribute to a mutual exchange of knowledge. During the visits, the candidate will collect data and conduct fieldwork. The data will be analysed though the lens of spatial and social scrutiny, an optic with which an ER with a background in geography, spatial planning, and sociology is already familiar.;183454,8;183454,8;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;UK;;;;1;0;0;1;0;0 208584;746358;SHADOWS;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;SHADOWS: Tackling Undeclared Work in the European Union;2017-09-01;2019-08-31;;Across the member states of the European Union and beyond, paid transactions occur that are not declared to the state for tax, social security and/or labour law purposes when they should be declared. This is not a minority practice and thus tackling undeclared work has become a core issue on the policy agendas of supra-national agencies and governments (European Commission, ILO). Reviewing the literature, it becomes quickly apparent that not only are there two distinct approaches, namely a ‘rational economic actor’ approach that tackles undeclared work by ensuring that payoff from undeclared work is outweighed by the costs, and a ‘social actor’ approach grounded in a view that undeclared work arises when tax morale is low, but also an emergent debate about whether these are complementary or competing approaches. This Fellowship aims to advance knowledge, by evaluating not only the effectiveness of using each approach to reduce undeclared work in different contexts, but also develops new understandings of the most effective overall approach by for the first time analysing interaction effects (between deterrents and tax morale, and vertical and horizontal trust) in various contexts. Considering the ambitious objective of advances a new theory for explaining and tackling the undeclared work, the main focus of the project is to ensure that all four types of triangulation, namely methodological triangulation, data triangulation, theory triangulation and investigator triangulation (interdisciplinary board) are addressed. As such, four extensive datasets are used as well as in-depth interviews in two countries with contrasting contexts of undeclared work (UK and Romania). This project conducted under the supervision of Prof Colin C. Williams, and the Cluster for Research on the Informal Sector and Policy team, will greatly increase our understanding of the undeclared economy and will provide evidence-based policy relevant findings.;195454,8;195454,8;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;THE UNIVERSITY OF SHEFFIELD;UK;;;;1;0;0;1;0;0 210227;740750;DAREnet;SIGNED;"H2020-EU.3.7.6.;H2020-EU.3.7.2.;H2020-EU.3.7.3.;H2020-EU.3.7.1.;H2020-EU.3.7.7.;H2020-EU.3.7.8.;H2020-EU.3.7.5.";SEC-21-GM-2016-2017;H2020;DAnube river region Resillience Exchange network;2017-09-01;2022-08-31;;"The DAREnet project is to support flood management practitioners across the EU Danube River region and from different disciplines to deepen and broaden their Research, Development and Innovation related collaboration (=RDI). DAREnet will build a multi-disciplinary community of practitioners, operating in a network of civil protection organisations, and supported by a broad range of stakeholders from policy, industry and research. Together they will build a transnational and interdisciplinary ecosystem to foster synergies, innovation and its uptake. One of the key-results of DAREnet will be a regularly updated RDI Roadmap highlighting promising innovation opportunities to cope with the main environmental and societal challenges of the region. It will provide concrete perspectives for the further development, industrialisation and uptake of innovations of highest relevance for practitioners. The Roadmap will be the result of a systematic assessment and prioritisation of promising innovations, including standardisation to foster the development of common capabilities. The RDI Roadmap will also lay the basis for concrete innovation initiatives, practitioner-driven and “bottom-up”, building a unique portfolio of joint innovation concepts for the Danube river region. To reach sustainable impact, DAREnet will draw upon synergies with the modules and facilities of the EUCPM and the regional strategies for flood prevention and risk management of the ICPDR and EUSDR. DAREnet will promote the RDI Roadmap and Portfolio to political key-stakeholders on national, regional and European level, and will also prospect institutional options to ensure the continuity of the DAREnet innovation process after project end.";3500000;3500000;H2020-SEC-2016-2017-1;/CSA;BUNDESMINISTERIUM DES INNERN;DE;"FUNDATIA CENTRUL NATIONAL APPEL PENTRU MANAGEMENTUL DEZASTRELOR;International Commission for the Protection of the Danube River;MAGYAR POLGARI VEDELMI SZOVELSEJ;STAD GEEL;DEUTSCHES ZENTRUM FUER LUFT - UND RAUMFAHRT EV;OSTERREICHISCHES ROTES KREUZ;ARTTIC;ISEM-INSTITUT PRE MEDZINARODNU BEZPECNOST A KRIZOVE RIADENIE, NO;MINISTARSTVO UNUTRASNJIH POSLOVA REPUBLIKE SRBIJE;ITTI SP ZOO;UNIVERISTET U BEOGRADU,FAKULTET BEZBEDNOSTI;Drzavna uprava za zastitu i spasavanje;GLAVNA DIREKTSIA POJARNA BEZOPASNOST I ZASHTITA NA NASELENIETO";"RO;AT;HU;BE;DE;FR;SK;RS;PL;HR;BG";;1;0;0;1;0;0 209144;724544;AveTransRisk;SIGNED;H2020-EU.1.1.;ERC-2016-COG;H2020;Average - Transaction Costs and Risk Management during the First Globalization (Sixteenth-Eighteenth Centuries);2017-07-01;2022-06-30;;"This project focuses on the historical analysis of institutions and their impact on economic development through the investigation of a legal instrument – general average (GA) – which underpins maritime trade by redistributing damages’ costs across all interested parties. This will be pursued through the comparative investigation of GA in those European countries where substantial data exists: Italy, Spain, England, France and the Low Countries (1500-1800). Average and insurance were both created in the Middle Ages to facilitate trade through the redistribution of risk. Insurance has been widely studied, average – the expenses which can befall ships and cargoes from the time of their loading aboard until their unloading (due to accidents, jettison, and unexpected costs) – has been neglected. GA still plays an essential role in the redistribution of transaction costs, and being a form of strictly mutual self-protection, never evolved into a speculative financial instrument as insurance did; it therefore represents an excellent case of long-term effectiveness of a non-market economic phenomenon. Although the principle behind GA was very similar across Europe, in practice there were substantial differences in declaring and adjudicating claims. GA reports provide unparalleled evidence on maritime trade which, analysed quantitatively and quantitatively through a novel interdisciplinary approach, will contribute to the reassessment of the role played by the maritime sector in fostering economic growth during the early modern first globalization, when GA was the object of fierce debates on state jurisdiction and standardization of practice. Today they are regulated by the York-Antwerp Rules (YAR), currently under revision. This timely conjuncture provides plenty of opportunities for active engagement with practitioners, thereby fostering a creative dialogue on GA historical study and its future development to better face the challenges of mature globalization.";1854256;1854256;ERC-2016-COG;/ERC-COG;THE UNIVERSITY OF EXETER;UK;STICHTING VU;NL;;1;0;0;1;0;0 209708;722325;RESCUE;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2016;H2020;Interdependent Challenges of Reliability, Security and Quality in Nanoelectronic Systems Design;2017-04-01;2021-03-31;;"RESCUE ITN advances scientific competences and establishes an innovative training for Interdependent Challenges of Reliability, Security and Quality in Nanoelectronic Systems Design. Today, nanoelectronic systems are at the core of all industry sectors and deployed in life-critical application domains, such as healthcare, transportation, automotive and security, serving societal needs in Europe. They are being combined into Internet-of-Things and Cyber-Physical Systems and, ultimately, represent the physical backbone of our increasingly digitised world. Here, the impact and consequences of in-field failures, security attacks or hardware defects can be catastrophic. At the same time, they are getting very hard to avoid due to the trends of extreme complexity and miniaturisation at the doorstep of physical limits. The objective is, first, to address the demanding and mutually dependent aspects of nanoelectronic systems design, i.e. reliability, security and quality, as well as corresponding electronic design automation tools. This will rescue and enhance design of complex systems at the next generation nanoelectronics technologies. Second, it is to provide early-stage researchers with innovative training in the involved disciplines and beyond, such that they will not only be able to face today and future challenges in nanoelectronics design but also be innovative, creative, and more importantly - have an entrepreneurial mentality. The latter will help to compile ideas into products and services for EU economic and social benefits. RESCUE addresses boosting Europe’s capabilities and leadership in nanoelectronics design and creation of qualified workforce and knowledge for industry. The consortium consists of leading European research groups competent to tackle the interdependent challenges in a holistic manner and to train new top-notch interdisciplinary professionals. The ITN is excellently balanced in terms of academic and industrial training and research facilities.";3755824,92;3755824,92;H2020-MSCA-ITN-2016;/MSCA-ITN-ETN;TALLINNA TEHNIKAULIKOOL;EE;"CADENCE;IHP GMBH - INNOVATIONS FOR HIGH PERFORMANCE MICROELECTRONICS/LEIBNIZ-INSTITUT FUER INNOVATIVE MIKROELEKTRONIK;IROC TECHNOLOGIES SA;INTRINSIC ID B.V.;POLITECNICO DI TORINO;BRANDENBURGISCHE TECHNISCHE UNIVERSITAT COTTBUS-SENFTENBERG;TECHNISCHE UNIVERSITEIT DELFT";"DE;FR;NL;IT";;1;0;0;1;0;0 209218;746221;Christianus Arabicus;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Ramon Llull (1232-1316): A Vernacular Writer Between Christianity and Islam;2017-10-02;2019-10-01;;"Ramon Llull’s Cent noms de Déu is the only versified work which entered the net of self-quotations and self-references which Llull used to promote and advertise his own production as a new alternative to his contemporary science and literature. In spite of his condemnation of troubadour lyric in his Book of Contemplation, Llull wrote many poems with a mnemonic-didactic purpose related to the learning of his epistemological system, i.e. the Art. Yet some his poems and some of his literary works are strongly related with contemporary literature and literary uses which he exploited and transformed to attract a wider audience. These literary ‘traps’ were a useful tool to spread the Art among all social classes, thus enhancing the fulfilment of Llull’s project: the conversion of all the unbelievers. The new critical edition of this work will help advancing my research on why Llull used poetic forms albeit he despised them and will provide new materials for understanding the circulation of culture and of ideas in the Mediterranean area in the XIII-XIV centuries. The outcome of this project will be a new critical edition of the text and a series of deliverables in which I will deeply analyse the context and co-texts of the poem, thanks to the expertise of the centres involved. Through this I will contribuite new material to philosophy/theology by investigating the Christian and Islamic interpretations of God's Names, to literary history understanding why Llull gave such an importance to a work which is not actually a proper poem but rather versified prose, analogous to the Arabic saj’ and to the early Office of the Hours' liturgical text, to linguistics by analysing the degree of Occitanisation of this work and in general of Llull’s poetry to understand how far his poetic language is from the abhorred troubadour lyric, finally to musicology by examining how this work was chanted, thus showing the interdisciplinary and cross-boundary value of Llull's production.";158121,6;158121,6;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;UNIVERSITAT DE BARCELONA;ES;;;;1;0;0;1;0;0 208627;748004;MiMEtiC;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Molecular mechanisms of the mechanical interaction between the cell nucleus and the actin cytoskeleton;2017-03-01;2019-02-28;;"The cytoskeleton plays a pivotal role in growth, development, and disease by sensing mechanical stress and mediating structural remodeling and cell functional responses. The cytoskeleton, which is linked directly to the nuclear lamina and thereby to chromatin, has recently been proposed to impact on chromatin remodeling and transcriptional activity. However, the mechanisms and biological consequences of force-dependent chromatin remodeling have remained elusive. Within this context main goals for my project are 1) to characterize nuclear rheology and stress transmission over the nuclear-cytoskeletal linkage, 2) to identify molecular mechanisms of force transmission into the nucleus and 3) to develop a numerical model of cell contractility and remodeling to systematically and quantitatively investigate the stress transmission to the nucleus to test my hypothesis that global force application to the nucleus can control nuclear mechanics, chromatin structure and transcriptional activity in a predictable, biologically meaningful way. This interdisciplinary project, integrating both cell/molecular biology of genome regulation and bioengineering, will advance our understanding of cellular mechanosensing and mechanotransduction, and carries therefore a strong transformative potential for discovering new strategies to mitigate many diseases where the interplay of mechanics and biochemistry are critical.";171460,94;171460,8;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;HELSINGIN YLIOPISTO;FI;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;DE;;1;0;0;1;0;0 208922;747374;BIRTHBRAZIL;TERMINATED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Birthing Abolition: Reproduction and the Gradual End of Slavery in Brazil;2017-09-01;2019-08-31;;BIRTHBRAZIL is an interdisciplinary project that will analyze how enslaved women’s reproductive trends and practices shaped the gradual abolition of slavery in the middle to large plantation holdings of Rio de Janeiro, Brazil from 1850 (the definitive end of the country’s slave trade) to final abolition in 1888. The project aims to contend that the struggle to end slavery was intimately entangled not only with elite understandings of slave reproduction but also with enslaved women’s own agency. To do so, it examines demographic trends among the enslaved population, elite views of enslaved women’s reproduction, and enslaved women’s own reproductive practices and agency. Like most Atlantic slave societies, the Brazilian slave population was reproduced through imports and not natural growth. Historians have argued that for 19th-century Rio de Janeiro state, harsh labour regimes and disease caused negative growth rates, dismissing the idea of “reproductive resistance”—the female enslaved practices of abortion and infanticide as purposeful attacks on the institution of slavery—popular in theories on Caribbean and US slavery. While enslaved women’s fertility control may not have caused negative population growth in 19th-century Rio de Janeiro state, BIRTHBRAZIL hypothesizes that enslaved women’s practices of fertility control played an important symbolic role in how elites understood and approached slavery itself. The findings of BIRTHBRAZIL are expected to demonstrate that enslaved women’s fertility control, both real and imagined, created the opportunity for abolitionists to implement the legal framework that abolished slavery. In doing so, the project provides historical background to current-day debates on reproductive rights, women’s health, and gender equality. The results will be disseminated through an academic monograph, peer-reviewed open-access publications, a website, an international conference, public history blogs, and a series of community lectures.;183454,8;183454,8;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;THE UNIVERSITY OF EDINBURGH;UK;;;;1;0;0;1;0;0 210059;742555;OMPorg;SIGNED;H2020-EU.1.1.;ERC-2016-ADG;H2020;Spatiotemporal organisation of bacterial outer membrane proteins;2017-09-01;2022-08-31;;"The outer membrane (OM) of Gram-negative bacteria protects against environmental insult and is central to pathogenesis hence finding ways to disrupt its integrity is a route towards new antibiotics. However, our understanding of OM biology is limited. In particular, how the OM is organised is largely unknown. My laboratory recently discovered spatiotemporal Outer Membrane Protein organisation (OMPorg) in Escherichia coli, a new organising principle that explains how OMPs are turned over. We found that OMPs cluster into islands that can be mimicked in supported bilayers using purified proteins. As cells grow, OMP islands are displaced to the poles by new islands, leading to binary partitioning of old OMPs in repository cells following septation. Another poorly understood aspect of OM biology is how protein bridges that connect the OM to the inner membrane (IM) mediate functions across the periplasm. We have discovered that the characteristic immobility of OMPs in vivo, caused by OMP clustering, becomes imposed on IM proteins (IMPs) when OMPs and IMPs become connected by protein bridges. These exciting new findings underpin OMPorg. I will focus on two species, E. coli and P. aeruginosa, and exploit the tools I have developed to ask four interrelated questions: 1. What is the molecular basis of OMP island formation? 2. Do OMPs influence IMP functionality via protein bridges? 3. Do repository cells endow bacterial populations with ‘OMP memory’? 4. Do OMP islands coordinate OM processes? I will address these questions through an interdisciplinary research programme incorporating protein chemistry and proteomics, ensemble and single molecule microscopy on live cells and in supported bilayers and molecular dynamics simulations. OMPorg will answer major outstanding questions concerning organisation in the bacterial OM and how this impacts the biology of the cell envelope, which will have ramifications for biomedicine and biotechnology.";2235815;2235815;ERC-2016-ADG;/ERC-ADG;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;UK;;;;1;0;0;1;0;0 209126;714793;APACHE;SIGNED;H2020-EU.1.1.;ERC-2016-STG;H2020;Atmospheric Pressure plAsma meets biomaterials for bone Cancer HEaling;2017-04-01;2022-03-31;;"Cold atmospheric pressure plasmas (APP) have been reported to selectively kill cancer cells without damaging the surrounding tissues. Studies have been conducted on a variety of cancer types but to the best of our knowledge not on any kind of bone cancer. Treatment options for bone cancer include surgery, chemotherapy, etc. and may involve the use of bone grafting biomaterials to replace the surgically removed bone. APACHE brings a totally different and ground-breaking approach in the design of a novel therapy for bone cancer by taking advantage of the active species generated by APP in combination with biomaterials to deliver the active species locally in the diseased site. The feasibility of this approach is rooted in the evidence that the cellular effects of APP appear to strongly involve the suite of reactive species created by plasmas, which can be derived from a) direct treatment of the malignant cells by APP or b) indirect treatment of the liquid media by APP which is then put in contact with the cancer cells. In APACHE we aim to investigate the fundamentals involved in the lethal effects of cold plasmas on bone cancer cells, and to develop improved bone cancer therapies. To achieve this we will take advantage of the highly reactive species generated by APP in the liquid media, which we will use in an incremental strategy: i) to investigate the effects of APP treated liquid on bone cancer cells, ii) to evaluate the potential of combining APP treated liquid in a hydrogel vehicle with/wo CaP biomaterials and iii) to ascertain the potential three directional interactions between APP reactive species in liquid medium with biomaterials and with chemotherapeutic drugs. The methodological approach will involve an interdisciplinary team, dealing with plasma diagnostics in gas and liquid media; with cell biology and the effects of APP treated with bone tumor cells and its combination with biomaterials and/or with anticancer drugs.";1499887;1499887;ERC-2016-STG;/ERC-STG;UNIVERSITAT POLITECNICA DE CATALUNYA;ES;;;;1;0;0;1;0;0 207834;707013;XYL-EID;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-GF;H2020;Determinants of Xylella fastidiosa host specificity;2016-10-01;2019-09-30;;"The pathogenic bacterium Xylella fastidiosa threatens European agricultural and natural flora through the loss of economically, environmentally and culturally important host plants such as grape, olive and oak. This bacterium was first detected in Italy in 2013 and then in Corsica,France. Although X. fastidiosa is a generalist pathogen, infecting over 300 plant species, only a few plant species develop disease symptoms, and these infections always depend on a specific pathogen genotype. Although X. fastidiosa has been studied for over 80 years in the U.S.A., the determinants of X. fastidiosa host specificity remain unknown. In other words, it is not know why genotypes cause disease in one plant species but not another. Understanding what constrains X. fastidiosa host specificity is of paramount importance because it is currently not possible to predict what plant species are susceptible in Europe; this represents a major knowledge gap and limiting an adequate analysis of the risks posed by X. fastidiosa. This project aims to answer this important question by studying populations of the bacterium that are already host specific as well as one epidemic population exploiting a novel plant species in the EU. This will be done through collaboration between U.C. Berkeley -a leading expert on this pathogen- and BGPI, a French institute with excellent expertise in population genomics and interdisciplinary research. Besides reinforcing the link between the U.S.A. and European research on a subject of major importance, this project will result in the training of a European expert on this emerging pathogen. It will also broaden the Experienced Researcher's knowledge in plant-pathogen interactions. Finally, this project intends to disseminate knowledge on X. fastidiosa to the European society through (i) a collaboration with the French non-academic institute ANSES, (ii) a website dedicated to this pathogen and (iii) a collaboration with European farmers and agronomical schools.";246668,4;246668,4;H2020-MSCA-IF-2015;/MSCA-IF-GF;INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE;FR;;;;1;0;0;1;0;0 207892;724663;InnoSpace;SIGNED;H2020-EU.1.1.;ERC-2016-COG;H2020;Revolutionizing fibre-wireless communications through space-division multiplexed photonics;2017-03-01;2022-02-28;;Next generation global telecommunication paradigms will require entirely new technologies to address the current limitations to massive capacity and connectivity. A full integration between optical fibre and wireless networks will be the key for the upcoming multigigabit-per-second 5G wireless communications and the era of Internet of Things. Microwave Photonics (MWP) is the multidisciplinary technology to achieve such a convergence. There is one revolutionary approach that has however been left untapped in finding innovative ways to increase the end user capacity and provide adaptive radiofrequency-photonic interfaces: exploiting space - the last available degree of freedom for optical multiplexing. Space-Division multiplexing (SDM) has been recently touted as a solution for the capacity bottleneck in digital communications by establishing independent light paths in a single fibre. My pioneering idea is to develop a novel area of application for SDM by exploiting for the first time its inherent parallelism to implement a broadband tuneable true time delay line for radiofrequency signals, which is the basis of multiple MWP functionalities. Within this project I envision an unprecedented revolution in fibre-wireless communications through the powerful concept of SDM that will lead to unique processing capabilities as well as to a reduction of size, weight and power consumption. My unique research background developed around the two core of this project, SDM and MWP, puts me in the privileged position to unify them in this truly interdisciplinary program, merging novel ideas and methods from physics, radiofrequency and photonics. Based on my profile, my preliminary results and the available infrastructure at my host organization, I am best positioned to successfully carry out this innovative high-gain/high-risk approach, which will lead to revolutionary advancements of the state of the art and prospective evolution of MWP for future ubiquitous communication scenarios.;1998500;1998500;ERC-2016-COG;/ERC-COG;UNIVERSITAT POLITECNICA DE VALENCIA;ES;;;;1;0;0;1;0;0 208461;724306;NONLINMAT;SIGNED;H2020-EU.1.1.;ERC-2016-COG;H2020;Functional extreme nonlinear nanomaterials;2017-08-01;2022-07-31;;"Metasurfaces that mimic artificial order in matter have recently opened an exciting gateway to reach unprecedented properties and functionality for the modification of light propagation. The artificial “atoms” and “molecules” of the metasurface can be tailored in shape and size, the lattice constant and inter-atomic interaction can be precisely tuned. Furthermore, using symmetry and polarization state properties topological Berry phase effects can greatly enhance the functionality of such surfaces. This project sets to explore the revolutionary physics of nonlinear optical Berry phase metasurfaces, covering nonlinear optical frequency generation and wave dispersion engineering as well as real-time reconfiguration of nonlinear optical properties. Novel unique nonlinear optical properties of metasurfaces that arise from their specific topological configurations open up exciting new venues for device development in the fields of all-optical data processing, optical meta-nanocircuits, phase conjugating perfect mirrors, and background-free nonlinear holography. The project will investigate the possibilities of strongly enhanced nonlinear light-matter interaction and novel nonlinear optical processes that are based on nonlinear topological Berry phase effects coupled to inter- and intersubband transitions of novel 2D materials. Single layers of transition metal dichalcogenides will allow reconfigurable nonlinear optical properties by changing the valley band transitions. The proposal covers the development of innovative large scale fabrication technologies, fundamental investigations of the origin and the design of effective nonlinearities, experimental characterizations, as well as device development. The findings of the project based on highly nonlinear reconfigurable metasurfaces based on symmetry and topological effects will impact interdisciplinary research fields including condensed matter physics, optoelectronics and biophotonics.";1915000;1915000;ERC-2016-COG;/ERC-COG;UNIVERSITAET PADERBORN;DE;;;;1;0;0;1;0;0 208547;740384;TheSBIE;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Thermodynamic Stabilization by Interface Engineering;2017-03-01;2020-02-29;;"'This GF proposal concerns nano-crystalline (NC) metallic alloys, unique materials having extremely small crystals (grains) which exhibit significantly improved mechanical properties over their conventional coarse-grained counterparts. Yet their inherently-large fraction of internal interfaces (grain boundaries, GBs), associated with excess energy, leads to coarsening of their structure at elevated temperatures during either fabrication, processing or service life. This results in a rapid deterioration of their properties, rendering them unsuitable for many applications. Compared with conventional, kinetic stabilization of NC alloys, which is limited and temporary in nature, the approach proposed here is of ‘Thermodynamic Stabilization by Interface Engineering’ employing solute segregation: alloying with elements which preferentially migrate to GBs to substantially reduce their excess energy, leading to a stable, tunable nano-scale grain size even at high temperatures. Employing a thermodynamic approach for engineering the structure and chemistry of interfaces in these materials stands a good chance of overcoming their fundamental stability hurdle with nature’s blessing. The main materials to be studied are iron-based alloys. In particular, NC iron-magnesium alloys have the potential for exceptional absolute and specific strength, exceeding that of the hardest steels. Experiments will be combined with mesoscale and atomistic simulations of thermodynamic, kinetic and mechanical properties. This international interdisciplinary research involves MIT (USA), Technion (Israel) and WWU (Germany), bridges physical metallurgy, nanotechnology and interface science. It will result in a deeper fundamental understanding of energetics and kinetics in NC alloys; tools for designing stable NC alloys with tailored mechanical properties; and commercialization of successful alloys. It shall thus strengthen the EU 'metallurgical infrastructure' according to the EC’s Metallurgy Road Map.'";263385;263385;H2020-MSCA-IF-2016;/MSCA-IF-GF;TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY;IL;;;;1;0;0;1;0;0 208464;724489;CellStructure;SIGNED;H2020-EU.1.1.;ERC-2016-COG;H2020;Structural cell biology in situ using superresolution microscopy;2017-06-01;2022-05-31;;"Supra-molecular protein machineries control diverse cellular processes. Knowing their structural organization is crucial for understanding their function. As classical structural biology techniques are limited in studying such assemblies in their natural cellular environment, there is a critical methodological gap inhibiting a direct link between structure and function. Consequently, the structural intermediates underlying a full activity cycle of a large multi-protein complex have been impossible to visualize. Recent advances in fluorescence microscopy, in particular the development of groundbreaking superresolution microscopy (SRM) methods, can now help bridge this gap. With this interdisciplinary proposal, my group will develop unique and innovative optical, biological and computational imaging technologies to determine the structural organization of multi-protein assemblies in their functional cellular context. We will reach this goal by developing a method to robustly measure the precise 3D arrangements of proteins in supra-molecular assemblies in situ with nanometer isotropic resolution based on supercritical-angle detection and by measuring their absolute stoichiometries with engineered counting standards. We will also develop new data analysis tools to statistically analyze such data, taking into account the functional cellular context measured with correlative superresolution and electron microscopy, multi-color SRM and molecular biology tools. We will apply these new methods to address key questions on endocytosis, a fundamental membrane trafficking process. Our aim is to determine a time-resolved 3D superresolution localization map of the yeast endocytic proteins during the major functional transitions and to integrate these data into a mechanistic model of endocytosis. Importantly, the methods we develop here can be applied to many other large protein-based machines, and thus have the potential to have high impact in other key areas of cell biology.";1686469,38;1686469,38;ERC-2016-COG;/ERC-COG;EUROPEAN MOLECULAR BIOLOGY LABORATORY;DE;;;;1;0;0;1;0;0 208476;725258;LATO;SIGNED;H2020-EU.1.1.;ERC-2016-COG;H2020;Large-Area Transparent Opto-Electronics using 2D Materials;2017-04-01;2022-03-31;;Research in 2D materials has increased dramatically since the first isolation of graphene in 2004, with diverse interdisciplinary studies. In the last few years, 2D material research expanded beyond graphene by the development of other 2D materials, such as monolayered transition metal dichalcogenides, black phosphorous, and Boron Nitride. There are hundreds of possible 2D crystals that can be isolated, with properties ranging from metallic, semi-metallic, semiconducting to insulating, depending on the material composition. Semiconducting 2D materials have attracting interest in next-generation electronics/opto-electronics such as transistors, photo-gated transistors, photo-detectors, solar cells, and light emitting devices (LEDs), molecular sensors and optical imaging sensors. The unique structural form of 2D materials provides several benefits over other existing materials: ultrathin, flexible, highly transparent, large surface to volume ratio, and 2D quantum confinement. High transparency LEDs are required for applications in transparent displays on glass panels. Many 2D based opto-electronic devices have used mechanical exfoliation from bulk crystals, but this is limited to small areas. Recent work on chemical vapour deposition (CVD) to grow wafer-scale 2D materials has opened up exciting opportunities for commercial exploitation and has accelerated the intensity of research in this field towards real applications. The vision of this proposal is to realize a new class of ultra-thin, flexible, large-area, transparent, high-sensitivity opto-electronic device arrays based on all 2D materials, with a focus on imaging sensors and LEDs. This will involve wafer-scale CVD synthesis of 2D materials including novel blue and green 2D semiconductors, optical spectroscopy to probe the interlayer interactions, atomic level structure-property correlations using advanced electron microscopy, and the nanoscale fabrication and testing of high efficiency devices.;1999318;1999318;ERC-2016-COG;/ERC-COG;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;UK;;;;1;0;0;1;0;0 208302;721176;StrainBooster;SIGNED;H2020-EU.1.1.;ERC-2016-COG;H2020;Enforced ATP wasting as a general design principle to rationally engineer microbial cell factories;2017-05-01;2022-04-30;;"One global challenge of humanity in the 21st century is the shift from a petrochemical to a bio-based production of chemicals and fuels. An enabling technology towards this goal is metabolic engineering which uses computational and experimental methods to construct microbial cell factories with desired properties. While it has been shown that genetically engineered microorganisms can, in principle, produce a broad range of chemicals, novel approaches to improve the performance of those strains are urgently needed to develop economically viable bioprocesses. To this end, we propose a new metabolic design principle to rationally engineer cell factories with high performance. Supported by a recent pilot study, we postulate that suitable genetic interventions combined with mechanisms that burn (waste) an extra amount of ATP (e.g., by artificial futile cycles) will increase product yield and productivity of many microbial production strains. Key objectives of StrainBooster are therefore: (1) to use computational techniques and metabolic models to identify gene knockout strategies whose coupling with ATP wasting mechanisms can boost the performance of microbial strains and to prove in silico that those strategies exist for many combinations of substrates, products, and host organisms; (2) to develop genetic modules that can robustly increase ATP dissipation in the cell; and (3) to experimentally demonstrate the power of the proposed strategy for selected production processes with Escherichia coli. To reach these ambitious goals, an interdisciplinary approach will be pursued combining theoretical and experimental studies and making use of innovative methods from systems and synthetic biology. If successful, StrainBooster will not only establish a new and ground-breaking strategy for metabolic engineering, it will also deliver novel computational tools and genetic parts facilitating direct application of the approach to design and optimize industrial fermentation processes.";1998750;1998750;ERC-2016-COG;/ERC-COG;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;DE;;;;1;0;0;1;0;0 207472;737038;TRANSPIRE;SIGNED;H2020-EU.1.2.1.;FETOPEN-01-2016-2017;H2020;Terahertz RAdio communication using high ANistropy SPIn torque REsonators;2017-01-01;2020-12-31;;"Current and future technological and societal demands require the transfer of vast amounts of data at speeds currently not available due to a lack of technology operating in the terahertz (THz) gap. TRANSPIRE will develop nano-scale THz-oscillators based on a new class of magnetic materials, which will function in this exact range and meet these demands. This will enable new functionalities with high societal impact, such as enabling remote hospitals, personal and substance security screening, medical spectrometry and imaging, geophysical and atmospheric research. Given the tuneability of their anisotropy, damping and magnetisation, newly discovered low-moment, ultra-high anisotropy field, highly spin-polarised ferrimagnets can enable terahertz technologies by exploiting magnetic resonance. Ferrimagnetic resonance will be excited by spin-transfer torque (STT) acting on the sub-lattice magnetisation, and detected via magnetoresistive effects. STT, so far only demonstrated in ferromagnetic systems, is the basis of all recent scalable magnetic random access memory designs. TRANSPIRE will optimize the materials, tuning their resonant properties and advancing the fundamental understanding of STT in two-sub-lattice systems. The breakthrough objective of a low-cost, compact, reliable, room-temperature terahertz technology has a huge potential, including on-chip and chip-to-chip data links. The natural outcome of the foundational work of TRANSPIRE will be to empower a number of high-potential actors to judge on the viability of spintronic terahertz technology and to be at the forefront of research, thus ensuring future industrial European leadership on the world stage. TRANSPIRE relies on coordinated interdisciplinary research in physics, chemistry, materials science, terahertz design and device engineering to ensure the success of this inherently high-risk endeavour, which can underpin the next wave of the Big Data revolution.";4430382,5;4430382,5;H2020-FETOPEN-1-2016-2017;/RIA;THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN;IE;"SWISSTO12 SA;NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU;HELMHOLTZ-ZENTRUM DRESDEN-ROSSENDORF EV";"CH;NO;DE";;1;0;0;1;0;0 207413;723991;CRYOMATH;SIGNED;H2020-EU.1.1.;ERC-2016-COG;H2020;Cryo-electron microscopy: mathematical foundations and algorithms;2017-03-01;2022-02-28;;The importance of understanding the functions of the basic building blocks of life, such as proteins, cannot be overstated (as asserted by two recent Nobel prizes in Chemistry), as this understanding unravels the mechanisms that control all organisms. The critical step towards such an understanding is to reveal the structures of these building blocks. A leading method for resolving such structures is cryo-electron microscopy (cryo-EM), in which the structure of a molecule is recovered from its images taken by an electron microscope, by using sophisticated mathematical algorithms (to which my group has made several key mathematical and algorithmic contributions). Due to hardware breakthroughs in the past three years, cryo-EM has made a giant leap forward, introducing capabilities that until recently were unimaginable, opening an opportunity to revolutionize our biological understanding. As extracting information from cryo-EM experiments completely relies on mathematical algorithms, the method’s deep mathematical challenges that have emerged must be solved as soon as possible. Only then cryo-EM could realize its nearly inconceivable potential. These challenges, for which no adequate solutions exist (or none at all), focus on integrating information from huge sets of extremely noisy images reliability and efficiently. Based on the experience of my research group in developing algorithms for cryo-EM data processing, gained during the past eight years, we will address the three key open challenges of the field – a) deriving reliable and robust reconstruction algorithms from cryo-EM data, b) developing tools to process heterogeneous cryo-EM data sets, and c) devising validation and quality measures for structures determined from cryo-EM data. The fourth goal of the project, which ties all goals together and promotes the broad interdisciplinary impact of the project, is to merge all our algorithms into a software platform for state-of-the-art processing of cryo-EM data.;1751250;1751250;ERC-2016-COG;/ERC-COG;TEL AVIV UNIVERSITY;IL;;;;1;0;0;1;0;0 207468;736937;M-CUBE;SIGNED;H2020-EU.1.2.1.;FETOPEN-01-2016-2017;H2020;MetaMaterials antenna for ultra-high field MRI;2017-01-01;2020-12-31;;"M-Cube aims at changing the paradigm of High-Field MRI and Ultra High-Field antennas to offer a much better insight on the human body and enable earlier detection of diseases. Our main objective is to go beyond the limits of MRI clinical imaging and radically improve spatial and temporal resolutions. The clinical use of High-field MRI scanners is drastically limited due to the lack of homogeneity and to the Specific Absorption Rate (SAR) of the Radio Frequency (RF) fields associated with the magnetic resonance. The major way to tackle and solve these problems consists in increasing the number of active RF antennas, leading to complex and expensive solutions. M-Cube solution relies on innovative systems based upon passive metamaterial structures to avoid multiple active elements. These systems are expected to make High-Field MRI fully diagnostically relevant for physicians. To achieve these expectations, M-Cube consortium will develop a disruptive metamaterial antenna technology. This we will able us to tackle both the lack of homogeneity and SAR barriers. Metamaterials are composite structured manmade materials designed to produce effective properties unavailable in nature (e.g. negative optical index). They allow us to tailor electromagnetic waves at will. Thus, the scientifically ambitious idea is to develop antennas based on this unique ability for whole body coil. This technological breakthrough will be validated by preclinical and clinical tests with healthy volunteers. M-Cube gathers an interdisciplinary consortium composed of academic leaders in the field, eight universities, and two promising SMEs. Physicists, medical doctors and industrial actors will work closely all along the implementation of the project to guarantee the success this novel approach, a “patient-centered” solution which will pave the way for a more accurate diagnosis in the context of personalized medicine and will enable to detect a disease much earlier that is currently possible.";4582346,25;3945346,25;H2020-FETOPEN-1-2016-2017;/RIA;UNIVERSITE D'AIX MARSEILLE;FR;"COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES;SAINT PETERSBURG NATIONAL RESEARCH UNIVERSITY OF INFORMATION TECHNOLOGIES, MECHANICS AND OPTICS;UNIVERSITE CATHOLIQUE DE LOUVAIN;AALTO KORKEAKOULUSAATIO SR;MULTIWAVE TECHNOLOGIES AG;UNIVERSITAIR MEDISCH CENTRUM UTRECHT;THE AUSTRALIAN NATIONAL UNIVERSITY;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;MR COILS BV";"FR;RU;BE;FI;CH;NL;AU";;1;0;0;1;0;0 207455;734548;ZIKAlliance;SIGNED;H2020-EU.3.1.3.;SC1-PM-22-2016;H2020;A global alliance for Zika virus control and prevention;2016-10-01;2020-09-30;;"'ZIKAlliance is a multidisciplinary project with a global 'One Health' approach, built: on a multi-centric network of clinical cohorts in the Caribbean, Central & South America; research sites in countries where the virus has been or is currently circulating (Africa, Asia, Polynesia) or at risk for emergence (Reunion Island); a strong network of European and Brazilian clinical & basic research institutions; and multiple interfaces with other scientific and public health programmes. ZIKAlliance will addrees three key objectives relating to (i) impact of Zika virus (ZIKV) infection during pregnancy and short & medium term effects on newborns, (ii) associated natural history of ZIKV infection in humans and their environment in the context of other circulating arboviruses and (iii) building the overall capacity for preparedness research for future epidemic threats in Latin America & the Caribbean. The project will take advantage of large standardised clinical cohorts of pregnant women and febrile patients in regions of Latin America and the Caribbean were the virus is circulating, expanding a preexisting network established by the IDAMS EU project. I will also benefit of a very strong expertise in basic and environmental sciences, with access to both field work and sophisticated technological infrastructures to characterise virus replication and physiopathology mechanisms. To meet its 3 key objectives, the scientific project has been organised in 9 work packages, with WP2/3 dedicated to clinical research (cohorts, clinical biology, epidemiology & modeling), WP3/4 to basic research (virology & antivirals, pathophysiology & animal models), WP5/6 to environmental research (animal reservoirs, vectors & vector control) , WP7/8 to social sciences & communication, and WP9 to management. The broad consortium set-up allow gathering the necessary expertise for an actual interdisciplinary approach, and operating in a range of countries with contrasting ZIKV epidemiological status.'";15684925,99;11964209;H2020-SC1-2016-RTD-Zika;/RIA;INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE;FR;"ACADEMISCH ZIEKENHUIS LEIDEN;FOLKEHELSEINSTITUTTET;UNIVERSITE DE LIEGE;UNIVERSIDADE FEDERAL DE MINAS GERAIS;UNIVERSIDADE FEDERAL DE GOIAS;UNIVERSITA DEGLI STUDI DI SIENA;INSTITUT LOUIS MALARDE;UNIVERSITE LYON 1 CLAUDE BERNARD;STIFTUNG TIERAERZTLICHE HOCHSCHULE HANNOVER;INSTITUTO MEXICANO DEL SEGURO SOCIAL;OTTO-VON-GUERICKE-UNIVERSITAET MAGDEBURG;EUROPEAN MOLECULAR BIOLOGY LABORATORY;INSTITUTO DE HIGIENE E MEDICINA TROPICAL;UNIVERSITAETSKLINIKUM BONN;COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES;ACADEMISCH ZIEKENHUIS GRONINGEN;INSTITUT PASTEUR DE NOUVELLE-CALEDONIE;INSTITUT PASTEUR DE DAKAR;UNIVERSIDADE NOVA DE LISBOA;Universidad Industrial de Santander;INSERM - TRANSFERT SA;INSTITUT PASTEUR OF SHANGHAI, CHINESE ACADEMY OF SCIENCES;UNIVERSITE RENNES II;FUNDACAO OSWALDO CRUZ;INSTITUT PASTEUR DU CAMBODGE FOUNDATION;LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE ROYAL CHARTER;STICHTING HET NEDERLANDS KANKER INSTITUUT-ANTONI VAN LEEUWENHOEK ZIEKENHUIS;INSTITUT PASTEUR;UNIVERSITAT DE BARCELONA;INSTITUT DE RECERCA I TECNOLOGIA AGROALIMENTARIES;CHARITE - UNIVERSITAETSMEDIZIN BERLIN;SOSECALI C LTDA;FONDAZIONE EDMUND MACH;FUNDACAO BAHIANA DE INFECTOLOGIA;UNIVERSITAETSKLINIKUM HEIDELBERG;UNIVERSITAT ZURICH;EIDGENOESSISCHES DEPARTEMENT DES INNERN;UNIVERSIDAD PERUANA CAYETANO HEREDIA;WAGENINGEN UNIVERSITY;FUNDACAO FACULDADE DE MEDICINA;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM;UNIVERSITE D'AIX MARSEILLE;FONDAZIONE PER L'ISTITUTO DI RICERC A IN BIOMEDICINA;UNIVERSITY OF GLASGOW;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;BERNHARD-NOCHT-INSTITUT FUER TROPENMEDIZIN;Laboratorio Nacional de Computacao Cientifica;INSTITUT DE RECHERCHE POUR LE DEVELOPPEMENT;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;KATHOLIEKE UNIVERSITEIT LEUVEN;INSTITUTO NACIONAL DE SALUD PUBLICA;AGENCE NATIONALE DE LA SECURITE SANITAIRE DE L ALIMENTATION DE L ENVIRONNEMENT ET DU TRAVAIL;INSTITUTO DE MEDICINA TROPICAL PEDRO KOURI;JANSSEN PHARMACEUTICA NV";"NL;NO;BE;BR;IT;PF;FR;DE;MX;PT;NC;SN;CO;CN;KH;UK;ES;EC;CH;PE;CU";;1;0;0;1;0;0 206835;731366;ICPerMed Secretariat;SIGNED;H2020-EU.3.1.6.;SC1-HCO-05-2016;H2020;Secretariat for the International Consortium for Personalised Medicine (IC PerMed);2016-11-01;2020-10-31;;"The potential of Personalised Medicine (PM) is to improve prevention, diagnosis and treatment of diseases by taking into account individuals' genotypes and phenotypes as well as other biomedical, life style and environmental data. In the last decade, significant advancements have been made especially for cancer or rare diseases. However, due to fragmentation and high upfront-investments the implementation of PM remains challenging, besides the various ongoing research and implementation actions on European, national and regional level. To overcome these hurdles, the International Consortium for Personalised Medicine (ICPerMed) is currently being initiated as a joint endeavour of the European Commission (EC) and more than 20 Member States. ICPerMed aims at aligning present as well as future efforts in all areas of PM by fostering international coordination of research and innovation funding. For this purpose, ICPerMed will develop and operate a European platform for collaboration between funders of PM research. It will promote an interdisciplinary approach to PM and generate policies, best practices, guidelines, and standards. ICPerMed secretariat will substantially contribute to the success of ICPerMed by efficiently coordinating all consortium activities, by implementing an effective dissemination plan and by assisting in the development of a sustainability strategy. By monitoring ongoing research funding activities in Europe and beyond, the secretariat will serve as the basis for evidence-informed allocation of research funding. ICPerMed secretariat will provide professional support in organising ICPerMed events and the meetings of ICPerMed bodies. In addition, ICPerMed secretariat will guide the dialogue with relevant stakeholders and initiatives. The organisational and logistical support of a secretariat will maximise the unique and long-term impact of ICPerMed by strengthening Europe's leading role in the successful implementation of PM in the global context.";1996722,5;1996722,5;H2020-SC1-2016-RTD;/CSA;DEUTSCHES ZENTRUM FUER LUFT - UND RAUMFAHRT EV;DE;"INSTITUTO DE SALUD CARLOS III;MINISTERO DELLA SALUTE;AGENCE NATIONALE DE LA RECHERCHE";"ES;IT;FR";;1;0;0;1;0;0 206771;734541;EOXPOSURE;SIGNED;H2020-EU.1.3.3.;MSCA-RISE-2016;H2020;TOOLS FOR MAPPING HUMAN EXPOSURE TO RISKY ENVIRONMENTAL CONDITIONS BY MEANS OF GROUND AND EARTH OBSERVATION DATA;2017-03-01;2021-02-28;;"The goal of the EOxposure project is to build tools to quantify the exposure of population and economic assets to multiple risks using novel information layers from current and future Earth Observation (EO) missions, as well as the growing sensor web on the ground. The project exploits the novel concept of the human EXPOSOME, i.e. the set of exposures to which an individual is subjected through its own existence. It includes the entire history of interactions with the environment, including air and water quality, food and exercises, as well as living habits and diseases that may spread. The cutting-edge fusion of this concept with EO and sensor data aims at measuring the human exposure to threats that are external to each individual, and quantify the interactions between human beings and the environment. By building geospatial information tools upon data coming from multiple sources, at different spatial and temporal scales, the EOxposure project aims at providing free public services, enabling citizens to understand the threats to which they are exposed, and decision makers to take more informed and effective actions against them. Specifically, EOxposure will focus on threats connected to housing conditions, disease spread, as well as security and health issues in urban and peri-urban areas, where population is concentrated. The new tools will build upon the consortium expertize on nutrition- and vector-borne disease models, urban heat monitoring and material characterization, satellite data processing, and geospatial data fusion, realizing interdisciplinary working groups dedicated to the above mentioned applications. To do so, EOxposure enrolls institutions from Europe and South America, merging expertises on exposure to risk in both developed and developing countries.";324000;270000;H2020-MSCA-RISE-2016;/MSCA-RISE;UNIVERSITA DEGLI STUDI DI PAVIA;IT;"ECOLE ROYALE MILITAIRE - KONINKLIJKE MILITAIRE SCHOOL;UNIVERSIDAD DE EXTREMADURA";"BE;ES";;1;0;0;1;0;0 206981;716220;SweetAim;SIGNED;H2020-EU.1.1.;ERC-2016-STG;H2020;Selective glycoimmuno-targeting for cancer therapy;2016-12-01;2021-11-30;;Immunotherapy recently became an important alternative to conventional treatment regimes, yet cancer remains a universal leading cause of death. Thus, novel cancer theranostic approaches are still much desired. Although altered cell surface glycosylation is one of the hallmarks of cancer, targeting this ‘sweet aim’ for cancer therapy has been elusive, largely due to carbohydrates poor immunogenicity and the low affinity of antibodies against them. A red meat-derived carbohydrate antigen is a novel immunogenic moiety providing a key to unlock the theranostic potential of tumor-associated carbohydrate antigens. This foreign non-human sugar can be acquired only through the diet and subsequently appears on diverse cell surface glycoconjugates as ‘self’, accumulating mostly on carcinomas, and resulting in a polyclonal xeno-autoantibodies response. I have shown that such antibodies have both diagnostic and therapeutic potential, although basic understanding of their specificity and potency is scarce. The primary objective of this proposal is to design a novel personalized cancer therapeutic approach based on xeno-autoantibodies against the dietary sugar antigen. We propose an innovative interdisciplinary approach crossing the boundaries of cancer research, glycosciences, immunology and nanotechnology, with cutting-edge technologies, to design, engineer, screen and fully investigate potent targeting of ‘SweetAim’ moieties. Our discovery line is based on a two-arms platform to generate optimized antibodies for passive/active therapy, together with refined tumor cells through glyco-engineering/reprogramming for unveiling novel theranostics, finally evaluated both in vitro and in vivo. I expect our groundbreaking achievements will lead to promising new clinical tools, particularly for cancer, but also for other chronic inflammation-mediated diseases. Importantly, it will establish fundamental new concepts regarding carbohydrate recognition and response by the immune system.;1479995;1479995;ERC-2016-STG;/ERC-STG;TEL AVIV UNIVERSITY;IL;;;;1;0;0;1;0;0 206938;714253;FAFC;SIGNED;H2020-EU.1.1.;ERC-2016-STG;H2020;Foundations and Applications of Functional Cryptography;2017-02-01;2022-01-31;;"'Modern cryptography has successfully followed an 'all-or-nothing' design paradigm over the years. For example, the most fundamental task of data encryption requires that encrypted data be fully recoverable using the encryption key, but be completely useless without it. Nowadays, however, this paradigm is insufficient for a wide variety of evolving applications, and a more subtle approach is urgently needed. This has recently motivated the cryptography community to put forward a vision of 'functional cryptography': Designing cryptographic primitives that allow fine-grained access to sensitive data. This proposal aims at making substantial progress towards realizing the premise of functional cryptography. By tackling challenging key problems in both the foundations and the applications of functional cryptography, I plan to direct the majority of our effort towards addressing the following three fundamental objectives, which span a broad and interdisciplinary flavor of research directions: (1) Obtain a better understanding of functional cryptography's building blocks, (2) develop functional cryptographic tools and schemes based on well-studied assumptions, and (3) increase the usability of functional cryptographic systems via algorithmic techniques. Realizing the premise of functional cryptography is of utmost importance not only to the development of modern cryptography, but in fact to our entire technological development, where fine-grained access to sensitive data plays an instrumental role. Moreover, our objectives are tightly related to two of the most fundamental open problems in cryptography: Basing cryptography on widely-believed worst-case complexity assumptions, and basing public-key cryptography on private-key primitives. I strongly believe that meaningful progress towards achieving our objectives will shed new light on these key problems, and thus have a significant impact on our understanding of modern cryptography.'";1307188;1307188;ERC-2016-STG;/ERC-STG;THE HEBREW UNIVERSITY OF JERUSALEM;IL;;;;1;0;0;1;0;0 205846;701883;TRAPRODIG;CLOSED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Trauma Studies in the Digital Age: The Impact of Social Media on Trauma Processing in Life Narratives and in Trauma Literature: the Case of Hungary;2016-09-01;2018-08-31;;"The aim of the TRAPRODIG project is to analyse cultural and literary trauma processing in the framework of digital memory studies, particularly in relation to the similarities and differences of collective trauma processing and trauma literature in modern democracies and dictatorships; with a special trans-cultural focus on the case of Hungary as a post-socialist country with unresolved twentieth century collective traumas and on life narratives of Hungarian migrants in Europe, especially in the United Kingdom. The interdisciplinary scientific goal of the project is to introduce the concept of “digital (cultural and literary) trauma processing” and develop the scientific field of “digital trauma studies” at the intersection of digital memory studies and cultural trauma studies; based on the outcomes of the two way knowledge transfer in the training-through research of the applicant, who is an expert on literary and cultural trauma studies, at the leading research centre of cultural and digital memory studies at the University of Amsterdam. The TRAPRODIG project is of clear relevance to the Marie Sklodowska-Curie actions programme as it will contribute to a better understanding of the link of current cultural developments to the collective traumas of the past in post-socialist countries; it draws attention to the voices of contemporary migrants within the European cultural framework; and it will also add significantly to the mapping of trauma literature and life narratives in Europe by analysing how the 21st century digital environment influences both personal and collective trauma processing in local, national and trans-national communities within Europe.";177598,8;177598,8;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;UNIVERSITEIT VAN AMSTERDAM;NL;;;;1;0;0;1;0;0 205496;722619;Foie Gras;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2016;H2020;Bioenergetic Remodeling in the Pathophysiology and Treatment of Non-Alcoholic Fatty Liver Disease;2017-01-01;2020-12-31;;FOIE GRAS provides innovative training for 13 early stage researchers (ESRs) to answer two critical and unanswered questions: a) Is hepatic bioenergetic remodelling involved in NAFLD pathogenesis, and target for stratification or therapeutic/lifestyle interventions? and b) Is the disruption of the gut-liver axis involved in NAFLD progression? In Western Societies, there has been a recent surge of non-alcoholic fatty liver disease (NAFLD). Its progression to nonalcoholic steatohepatitis (NASH) is a leading risk factor for development of Type 2 diabetes, cirrhosis, and hepatocellular carcinoma. FOIE GRAS is first in supporting a cohesive and synergistic intersection of complementary and interdisciplinary training skills from academic and non-academic partners. FOIE GRAS combines strong scientific expertise with integrated and complementary training in translational research, clinical practice, technology commercialization, and public outreach, the combination of which in targeting NAFLD is lacking in the EU. Industrial partners CETICS, Mediagnost and Seahorse Biosciences provide experience on technology commercialization alongside scientific contributions while the affiliated patient organization will contribute with important training in societal awareness topics. ESRs training will utilize network-wide workshops and secondments to foster translation of basic research to clinical applications and SME creation. This diverse yet integrated skill set enhances the employment prospects of the trained researchers in both academic and non-academic sectors. Researchers will be endowed with excellent basic scientific knowledge and timely technology transfer know-how for developing novel therapeutic approaches for reversing the burden of NAFLD, thereby advancing both health and economic well-being of European citizens and approaching NAFLD research in the EU from its counterparts in the US and Asia.;3202195,68;3202195,68;H2020-MSCA-ITN-2016;/MSCA-ITN-ETN;CENTRO DE NEUROCIENCIAS E BIOLOGIACELULAR ASSOCIACAO;PT;"FYZIOLOGICKY USTAV AKADEMIE VED CESKE REPUBLIKY VEREJNA VYZKUMNA INSTITUCE (VVI);INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE;HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH;AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS;CONSIGLIO NAZIONALE DELLE RICERCHE;UNIVERSIDADE DO PORTO;INSTYTUT BIOLOGII DOSWIADCZALNEJ IM. M. NENCKIEGO POLSKIEJ AKADEMII NAUK;UNIVERSITA DEGLI STUDI DI BARI ALDO MORO;Faculdade de Farmácia da Universidade de Lisboa";"CZ;FR;DE;ES;IT;PT;PL";;1;0;0;1;0;0 205613;722338;PlantHUB;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2016;H2020;PlantHUB - Boosting technology transfer and responsible research and innovation (RRI) in plant sciences;2016-12-01;2020-11-30;;In PlantHUB will capture the academic, industrial and regulatory expertise from 5 world-class universities, 1 governmental organization, 7 enterprises including 4 SMEs to train 10 ESRs in skills and competencies necessary to apply responsible research and innovation (RRI) in the area of plant breeding and production. We wish to address the demand of RRI leadership in plant science related research and diffusion of innovation. The individual research projects are demand-driven, responding to the needs of companies - particular SMEs - to increase R&I capacities. The outcomes are new molecular tools for plant breeding, new forage, cereal and oil crop varieties, non-invasive imaging and phenotyping technologies, intelligent lighting systems for plant growth, new software and services for complex genomic analyses, and plant product quality. PlantHUB industrial doctoral programme is ground-breaking in a number of respects: (i) doctoral training is placed into an entrepreneurial environment of leading public and private organisations (ii) it combines practical hands-on R&D and technology transfer in plant breeding and production with RRI training and practise. On completion of the training, graduates will have deep interdisciplinary knowledge of plant breeding, crop improvement, high-throughput technologies, isotope and big data analysis. In combination with a portfolio of transferable skills they will be able to take a lead in stakeholder & public engagement, innovation management, technology transfer and entrepreneurship. Our programme will become a flagship example at the forefront of intersectoral research, underpinned with a carefully created training curriculum to foster awareness, know-how, expertise and competence in RRI.;2617989,18;2617989,18;H2020-MSCA-ITN-2016;/MSCA-ITN-EID;EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH;CH;"BASECLEAR BV;LEMNATEC GMBH;NPZ INNOVATION GMBH;UNIVERSITAT BASEL;AGROISOLAB GMBH;CARLSBERG AS;HELIOSPECTRA AB;UNIVERSITAT ZURICH;DEUTSCHE SAATVEREDELUNG AG";"NL;DE;CH;DK;SE";;1;0;0;1;0;0 206042;702048;NEIL;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Nanoscale Electrochemistry in Ionic Liquids;2016-10-17;2018-10-16;;"This proposal presents unique approaches for the characterization of charged interfaces and interfacial phenomena at the nanoscale in ionic liquid (IL) media, through the implementation of innovative, quantitative high resolution scanning probe (electrochemical) microscopy techniques. The overarching goal is to introduce new methodology that will enable a comprehensive understanding of interfacial phenomena in these neoteric solvents and bring major new insights on the functional properties of surfaces and nanomaterials. The scientific scope of this project involves: (i) the characterization and mapping of the electrical double layer at IL/electrode interfaces; (ii) visualization of reactivity at the nanoscale using functional imaging techniques and; (iii) single-entity electrochemistry in ILs, from individual nanoparticles (NPs) to single molecules. The reactivity mapping and single NP studies will focus on assessing the electrocatalytic activity of novel nanomaterials (e.g., graphene, nanotubes, metal and metal-oxide NPs) towards the hydrogen evolution and oxygen reduction reactions, which are of fundamental and technological (e.g., fuel cells, lithium-air batteries, water splitting etc.) importance. The research proposal is highly interdisciplinary, and there is a natural synergistic fit between the Fellow’s profile and activities at the Host Warwick group. The proposal draws on Fellow’s strong background in electrochemistry, particularly his expertise in applying ILs in fundamental and applied electrochemical research, which will be married with the world-leading research on innovative nanoscale electrochemical imaging techniques developed at Warwick. With considerable support and world-class expertise from the Host group and its collaborators, this project will provide the applicant, Dr. Cameron Bentley, with an outstanding opportunity to develop personally and professionally, by pioneering a new area of research in a new geographic location.";183454,8;183454,8;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;THE UNIVERSITY OF WARWICK;UK;;;;1;0;0;1;0;0 206320;715618;CALC;SIGNED;H2020-EU.1.1.;ERC-2016-STG;H2020;Computer-Assisted Language Comparison: Reconciling Computational and Classical Approaches in Historical Linguistics;2017-04-01;2022-03-31;;"By comparing the languages of the world, we gain invaluable insights into human prehistory, predating the appearance of written records by thousands of years. The traditional methods for language comparison are based on manual data inspection. With more and more data available, they reach their practical limits. Computer applications, however, are not capable of replacing experts' experience and intuition. In a situation where computers cannot replace experts and experts do not have enough time to analyse the massive amounts of data, a new framework, neither completely computer-driven, nor ignorant of the help computers provide, becomes urgent. Such frameworks are well-established in biology and translation, where computational tools cannot provide the accuracy needed to arrive at convincing results, but do assist humans to digest large data sets. This project establishes a computer-assisted framework for historical linguistics. We pursue an interdisciplinary approach that adapts methods from computer science and bioinformatics for the use in historical linguistics. While purely computational approaches are common today, the project focuses on the communication between classical and computational linguists, developing interfaces that allow historical linguists to produce their data in machine readable formats while at the same time presenting the results of computational analyses in a transparent and human-readable way. As a litmus test which proves the suitability of the new framework, the project will create an etymological database of Sino-Tibetan languages. The abundance of language contact and the peculiarity of complex processes of language change in which sporadic patterns of morphological change mask regular patterns of sound change make the Sino-Tibetan language family an ideal test case for a new overarching framework that combines the best of two worlds: the experience of experts and the consistency of computational models.";1499437,5;1499437,5;ERC-2016-STG;/ERC-STG;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;DE;;;;1;0;0;1;0;0 206768;734381;CARBO-IMmap;SIGNED;H2020-EU.1.3.3.;MSCA-RISE-2016;H2020;Immune activity Mapping of Carbon Nanomaterials;2017-03-01;2021-02-28;;"'The CARBO-IMmap project involves key players in Europe, US, Qatar and China with the aim to advance the field of carbon nanomaterial development and their exploitation biomedical applications. The long-range goal of Carbo-IMmap is to develop a functional pipeline for the immune-characterization of carbon nanomaterials, for the qualitative and quantitative assessment in vitro and ex vivo of the human immune compatibility and immune activity of newly developed carbon materials. The project aims to: 1) design and synthetize a panel of 5 types of highly stable and water-soluble nanomaterials, characterized by finely tuned properties by controlling their size and composition, and to obtain these nanomaterials in large amounts with nearly identical size and shape and degree of functionalization; 2) achieve a quantitative understanding of the immune activity (stimulation/ anergy/ suppression) of the selected materials upon the 5 subpopulations of the immune blood cells; 3) correlate the physicochemical properties (size and chemical functionalization) of the nanomaterials with their immune properties; 4) establish a consolidated network between leading EU and extra-EU institutes to provide a stimulating international environment for talented young researchers; 5) advance the level of R&D in participant countries and foster technology transfer and dissemination; 6) raise the awareness of the general public on the prospects of carbon nanomaterials in future biomedical applications. Scientists will be formed by 'training by research' stays at host labs, leading to an interdisciplinary and international formation. Funding of this program will enable long-term, transformative research collaborations that will contribute to the integration and collaboration of research groups of 4 European Countries (Germany, Italy, France and Spain) and 3 key non-EU Countries: USA, China and Qatar.'";967500;796500;H2020-MSCA-RISE-2016;/MSCA-RISE;UNIVERSITA DEGLI STUDI DI TRIESTE;IT;"ASOCIACION CENTRO DE INVESTIGACION COOPERATIVA EN BIOMATERIALES- CIC biomaGUNE;UNIVERSITA DEGLI STUDI DI SASSARI;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;TECHNISCHE UNIVERSITAET DRESDEN";"ES;IT;FR;DE";;1;0;0;1;0;0 206731;715132;TRIPOD;SIGNED;H2020-EU.1.1.;ERC-2016-STG;H2020;The transition to a renewable electricity system and its interactions with other policy aims;2017-08-01;2022-07-31;;"In order to meet its long-term climate targets, the European Union has decided to reduce its power sector carbon emissions by 93-99% by 2050. This means that Europe aims to transition to a largely, or fully, renewable power system. This is however not the only energy policy aim: besides a transition to renewables, further aims include an energy efficiency increase and demand reduction; liberalisation of the power markets and exposure of renewables to competition; and europeanisation of renewable energy policy, power grids, and the creation of a European internal power market. Here, I investigate whether and how these policies interact and affect the chances for and costs of a transition to a renewable power system; how the other aims constrain the options for renewables; and how policy conflicts can be resolved. Current policy discourse treats these policy aims either as independent or synergistic. My hypothesis is that they are not at all independent and that pursuing the aims of demand reduction, liberalisation and europeanisation strongly influences the transition to renewables, and that the aims are partially antagonistic, implying a need for trade-offs. The purpose of my research is to test these hypotheses and explore the policy synergies or antagonisms, by investigating yet under-researched aspects of the interactions. These include how reaching the other aims influences the transition dynamics; how key actors may alter their behaviour due to such other developments; and how reaching another policy aim impacts the stability of a fully renewable power system. I adopt an interdisciplinary approach, drawing on transition research, engineering, political science and economics, with each perspective adding a piece of the puzzle. The answers will contribute to both the disciplinary and the policy-driven renewable energy research, and provide insights to help policy-makers define less conflicting policies, thus supporting the European transition to renewables.";1499940;1499940;ERC-2016-STG;/ERC-STG;INSTITUTE FOR ADVANCED SUSTAINABILITY STUDIES EV;DE;EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH;CH;;1;0;0;1;0;0 204934;706376;INVERTIDAL;CLOSED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Chromosomal rearrangements and diversification on environmental gradients;2016-09-01;2018-08-31;;"Chromosomal rearrangements (CRs) are considered to foster adaptation (and speciation) by protecting advantageous combinations of alleles from recombination. This is supported by the frequent observation of inversion clines linked to environmental gradients. However, direct evidence for the proposed allelic interactions within CRs and their role in diversification remains elusive. The rocky intertidal is a natural laboratory to study adaptation along gradients and its contribution to speciation. In particular, the parallel evolution of divergent ecotypes in Littorina saxatilis offers a unique opportunity to investigate the genetic basis of phenotypic variation associated with spatial environmental changes (i.e. the genomic architecture of adaptation and speciation). Although advances on genomics have allowed the identification of loci involved in these processes, the role of structural variation has not yet been tested. Here I propose an interdisciplinary project that will combine data on genome organization, genotype and phenotype with modelling and existing ecological and behavioural information; aiming to provide a more complete view of adaptation and diversification when facing abrupt environmental changes. Prof. Butlin, at the University of Sheffield, will give me access to a leading research group in adaptation and speciation genomics and to a highly stimulating department in evolutionary biology; while during two secondments (at University Pompeu Fabra and University of Bari) I will receive further specialized training on CR detection. These new skills in cutting-edge research will put me in a privileged position to establish myself as an independent researcher. The outcome of INVERTIDAL will not only have an impact on basic evolutionary knowledge but will also address a major societal concern (climate change) and give key information to biodiversity managers, helping to bridge research and decision-making, in line with the Horizon2020 framework.";183454,8;183454,8;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;THE UNIVERSITY OF SHEFFIELD;UK;;;;1;0;0;1;0;0 203550;713673;INPhINIT;SIGNED;H2020-EU.1.3.4.;MSCA-COFUND-2015-DP;H2020;Innovative doctoral programme for talented early-stage researchers in Spanish host organisations excellent in the areas of Science, Technology, Engineering and Mathematics (STEM).;2016-10-01;2021-09-30;;"'la Caixa' Banking Foundation (FBLC) is a Spanish private foundation that has as mission to contribute to the advance of people and society. FBLC ranks among the top 10 world foundations considering either endowment or annual budget. Since 1982 FBLC manages prestigious fellowship programmes. FBLC will launch a new doctoral programme, INPhINIT, in October 2016 that will increase the transnational, inter-sectoral and inter-disciplinary mobility of researchers, in line with the European Charter for Researchers, the Code of Conduct for the Recruitment of Researchers and the EU Principles for Innovative Doctoral Training. With a budget of 19,489,896 EUR (25% EU contribution, 75% FBLC own resources) and a duration of 5 years, the INPhINIT programme will have two calls and recruit 114 Early-Stage Researchers of any nationality willing to join an excellent host organisation in Spain, in the areas of Science, Technology, Engineering and Mathematics (STEM), including Bio and Health Sciences, areas in which Spain excels and has a critical mass to have impact. Researchers will be enrolled in a Doctoral Programme and be hosted by one of the 51 centres that collaborate with the programme. Host organisations hold certificates of excellences issued by the Spanish Government. Selection process will be open, transparent and merit-based and count with independent experts from different countries and sectors, with diverse and relevant expertise, seeking gender balance. ESRs will enjoy 3-year employment contracts with the host organisation of their choice (bottom-up approach), with the corresponding social security provisions. Researchers will establish a personal development career plan including transnational, inter-sectoral and interdisciplinary mobility opportunities. COFUND support will allow INPhINIT to recruit a larger number of researchers and reinforce its impact, as well as to further disseminate the Marie Sk³odowska-Curie actions high standards for research training. '";9417600;4708800;H2020-MSCA-COFUND-2015;/MSCA-COFUND-DP;FUNDACION BANCARIA CAIXA D'ESTALVISI PENSIONS DE BARCELONA LA CAIXA;ES;;;;1;0;0;1;0;0 203459;703682;MuseCoP4DT;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Design Thinking for Digital Heritage: Developing Communities of Design Practice for Visitor Experience;2016-07-01;2018-12-31;;"This project is firmly situated within Design Research focusing on the area of Design Thinking for Digital Heritage. This study aims to advance Design Research by conducting the first systematic analysis of Design Thinking culture in the particular domain of museums engaged in digital heritage projects. This research takes a qualitative approach to the study of Design Thinking by blending ethnographic methods with suitably adapted methods and concepts from Wenger’s Communities of Practice. Situated at the intersection of different academic fields, this project has an interdisciplinary character and brings different methodologies into dialogue, delivering an original and innovative contribution to existing literatures and enhancing theoretical and practical knowledge in Design Research.";195454,8;195454,8;H2020-MSCA-IF-2015;/MSCA-IF-EF-RI;UNIVERSITY OF LEICESTER;UK;;;;1;0;0;1;0;0 204524;704709;MATRIX;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Anthropogenic units detected by rare earth elements (REE) soil analysis in archaeological strata.;2016-06-01;2018-05-31;;"The aim of the innovative MATRIX project is to establish a new interdisciplinary and multidisciplinary methodological approach that combines archaeology, chemistry and geology for the identification of anthropogenic deposits in archaeological excavations through rare earth elements (REE) soil analysis, pushing current limitations of traditional chemical and sedimentology techniques. REE are a set of seventeen elements in the periodic table, specifically fifteen lanthanides as well as scandium and yttrium. Crucially, these elements are relatively abundant in the earth’s crust and thanks to their characteristics can be employed as unambiguous markers of soil provenance on archaeological sites worldwide. Many techniques may be able to reveal ancient human activities, however integrated approaches can be reinforced by the employment of REE patterns as proved by my previous and ongoing research; an approach that does not merely observe coarse differences between anthropogenic and non-anthropogenic sediments, but is also able to see finer nuances like the degree of human contributions to the formation of ancient soils (palaeosols), adding new ways to tackle a classic archaeological problem that has increasing modern relevance: how do we discern the impact of ancient human activities on the soils that are a pivotal component of environmental and economic sustainability. Agricultural human activities or livestock is reflected with higher REE concentrations compared with the natural REE soil level. Probably this is related to the enrichment in soil of the organic matter and this transformation remain fingerprinted in the REE concentrations at stratigraphic levels of any chronological period. In archaeological site or modern site were the presence of human activities has change the natural landscape REE method is an optimum skill to clarify the stratigraphic impact in the soil and as well the soil occupation and abandonment dynamics.";195454,8;195454,8;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;UNIVERSITY OF YORK;UK;;;;1;0;0;1;0;0 203175;712949;TECNIOspring PLUS;SIGNED;H2020-EU.1.3.4.;MSCA-COFUND-2015-FP;H2020;ACCIÓ programme to foster mobility of researchers with a focus in applied research and technology transfer;2016-07-01;2022-02-28;;"TECNIOspring PLUS Fellowship Programme is proposed by ACCIÓ, the Catalan Agency for Business and Competitiveness, attached to the Ministry for Business and Labour of the Government of Catalonia. With a budget of 10,044,000 € (circa 50% EU contribution) and a duration of 5 years, TECNIOspring PLUS programme will be addressed to experienced researchers, who will develop their research career in their area of interest, with focus on technology transfer. The programme will fund 72 fellowships, offering high-quality professional opportunities, with living plus mobility allowance well above the amount required by Marie Sklodowska-Curie WP, through its two types of mobility schemes, incoming and outgoing\return. Fellows will be free to choose their research project, with a focus on innovation and technology transfer, and a suitable host organisation fitting their individual needs and interests. The fellowship programme will have four selection rounds following fixed deadlines, allowing a fair competition between applicants. Calls for proposals will be advertised at international level, including EURAXESS website among others. TECNIOspring PLUS programme will receive joint applications of an experienced researcher and the host organisation of his/her choice (the beneficiary). Host organisations will be entities of the academic or industrial sector belonging to the Catalan Research and Technology Transfer System, recognized with the TECNIO accreditation. ACCIÓ already manages a COFUND project under FP7, TECNIOspring fellowship programme (GA n? 600388). TECNIOspring PLUS goes beyond the earlier grant. ACCIÓ wants to increase its impact and further align it with the best practices of the Marie Sk³odowska-Curie programmes by: increasing no. of fellowships and living allowances, opening the programme to industry, incorporating public engagement activities, offering interdisciplinary opportunities and fostering the international dimension.";10195200;5097600;H2020-MSCA-COFUND-2015;/MSCA-COFUND-FP;AGENCIA PER A LA COMPETITIVITAT DE LA EMPRESA;ES;;;;1;0;0;1;0;0 203188;713750;DOC2AMU;SIGNED;H2020-EU.1.3.4.;MSCA-COFUND-2015-DP;H2020;International, inter-sectoral and inter-disciplinary Doctoral Training Programme to Aix-Marseille University;2016-12-01;2021-11-30;;"DOC2AMU raised out of the willpower of the Provence Alpes Cote d’Azur key regional actors in Research and Innovation to offer to the most promising early stage researchers an international, inter-sectoral and inter-disciplinary innovative doctoral training programme. The excellence is ensured not only by the research ecosystem of Aix-Marseille University but also through the open, transparent, merit-based, impartial and equitable selection process set up to assess the perfect match between the proposed doctoral projects and the ESRs. Further to ensure the best career perspectives after ESR’s’ graduation, DOC2AMU set up an original training programme offering a training scheme combining options of the 3 international/inter-sectoral and interdisciplinary dimensions, including a comprehensive package of transferable skills training, along with a specific mentoring scheme involving an academic Supervisor, a non-academic and/or international tutor(s) and a Scientific & Training Supervisory Committee. Apart from the recruitment of 30 ESRs, it is expected that DOC2AMU will enhance skills of AMU ESRs including transferrable ones; upgrade AMU doctorate’s curriculum, by generalizing the innovative Doctorate Principles as a standard for all Doctoral training in AMU; reinforce AMU capacities to host talented international researchers in high standard working and improved employment conditions; intensify the cooperation and the alignment of AMU Human Resources practices between key regional academic and non-academic research and innovation players; develop new synergies on the regional territory; strengthen the innovative aspects of the Regional Doctoral programme and disseminating HR and training good practices in other Universities and Research organisations in PACA; and prioritize research projects focusing on the regional Research and Innovation Strategies for Smart Specialization strategies to create a regional leverage in terms of knowledge and innovation.";4708800;2354400;H2020-MSCA-COFUND-2015;/MSCA-COFUND-DP;UNIVERSITE D'AIX MARSEILLE;FR;;;;1;0;0;1;0;0 203306;702134;DemocInChange;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Effects of Institutional Change on Participatory Democracy and the Involvement of Civil Society Organisations;2017-01-01;2018-12-31;;"'DemocInChange understands the current challenges to EU integration as an opportunity to rethink the interface of civil society organisations (CSOs) and EU institutions as a basis for supranational participatory democracy. It does so by focusing on CSOs that aim to improve citizenship rights and participation for groups often marginalized in the policy-making process, more precisely by studying the effects of internal EU administrative reorganisation on the participation of CSOs in EU decision- and policy-making. DemocInChange impacts on the future of European integration by contributing to President Juncker's political priority 'A Union of Democratic Change', making European societies more innovative, inclusive and reflective. It provides a better understanding of the linkages between equality CSOs and EU institutions, the impact of the Commission on CSOs networks and their lobbying options. DemocInChange pursues three objectives: 1) innovative interdisciplinary state-of-the-art research assessing how the EU can improve its decision-making, 2) excellent training equipping with innovative and future-oriented skills and a sustainable network allowing jobs in academia, policy think tanks or CSOs, 3) mutual learning between academics, policy makers, civil society and students by innovative ICT tools. The objectives will be achieved by a comprehensive training program providing excellent training-through-research, one academic secondment educating in innovative analytical software and elearning, and one non-academic secondment to the European Parliament Think Tank. The three organizations provide fertile ground for disseminating research results to a variety of academic and non-academic audiences in short time. DemocInChange supports the Horizon 2020 goal of becoming the leading knowledge-based economy by bridging divisions between academia, civil society and EU institutions, and by creating a communicative and interactive elearning space.'";172800;172800;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;UNIVERSITEIT ANTWERPEN;BE;;;;1;0;0;1;0;0 203233;681379;SPRINT;SIGNED;H2020-EU.1.1.;ERC-CoG-2015;H2020;Ultra-Short Pulse laser Resonators IN the Terahertz;2016-09-01;2021-08-31;;"'Ultra-short light pulses with large instantaneous intensities can probe light-matter interaction phenomena, capture snapshots of molecular dynamics and drive high-speed communications. In a semiconductor laser, mode-locking is the primary way to generate ultrafast signals. Despite the intriguing perspectives, operation at Terahertz (THz) frequencies is facing fundamental limitations: engineering 'ultrafast' THz semiconductor lasers from scratch or finding an integrated technology to shorten THz light pulses are currently two demanding routes. SPRINT aims to innovatively combine the groundbreaking quantum cascade laser (QCL) technology with graphene, to develop a new generation of passive mode-locked THz photonic laser resonators, combined with unexplored electronic nanodetectors for ultrafast THz sensing and imaging. To achieve these ambitious objectives, the versatile quantum design of QCLs will be exploited to engineer the laser gain spectrum on purpose. Resonators of unusual symmetry and shape, like photonic quasi-crystals or random patterns, will be implemented, offering the flexibility to control and guide photons and the lithographic capability to embed miniaturized intra-cavity passive components to probe and modulate light. Graphene, owing to its gapless nature and ultrafast, gating-tunable carrier dynamic, will lead to a major breakthrough: integration in the THz QCL cavity will allow superbly manipulating its functionalities. Antenna-coupled quantum-dot nanowires will be also devised to sense and probe ultra-short THz pulses. The project will target radically new concepts and interdisciplinary approaches encompassing unconventional THz QCL micro-resonators, graphene and polaritonic THz saturable absorbers, non-linear ultra-low dimensional detection architectures. Pushing forward the understanding of ultrafast dynamics in complex THz electronic and photonic systems, SPRINT prospects new directions and long-term impacts on fundamental and applied science.'";1990011;1990011;ERC-2015-CoG;/ERC-COG;CONSIGLIO NAZIONALE DELLE RICERCHE;IT;;;;1;0;0;1;0;0 203308;702531;YouthCult;CLOSED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;The Cultural Experience of International Students: Narratives from North and South Europe;2016-09-01;2018-08-31;;"Young people are travelling more than ever before. Studying abroad is a growing and institutionalized practice, as in the Erasmus program. To find out what they’re getting out of this travelling, we have to get them to tell their stories and explore the meanings of their experience within the broader context of their lives. The results of this comparative study can usefully orient EU policymakers in sustaining young people in their transitional challenges – becoming adults, Europeans and citizens of a globalized world – fostering ongoing education in cultural diversity enhancing life for all Europeans. The key question is if and how students’ experiences abroad are contributing to overcoming cultural and social boundaries. Using a mixed-method and interdisciplinary approach, this innovative study investigates the meanings given by a group of 60 international students to their educational, cultural and overall life experience abroad (Finland and Italy). Through analysis of autobiographical-autoethnographical essays, ethnographical observations, focus groups and in-depth interviews I will address topics connected with self-construction processes in another culture: family of origin and its economic, social and cultural capital; perception of European social and cultural identity and sense of belonging to a “Cosmopolitan Generation”; fundamental cultural objects shaping the idea of Italy (South) Finland (North) and Europe in general; interaction with locals and involvement in the host culture; key life passages during students’ stay abroad. The narrative approach yields a clear, in-depth and comprehensive vision of what students abroad are actually doing and what they think about it. Beyond quantitative data, qualitative empirical material of this kind is rare; findings will offer unique insights on human life-span development, cultural globalization, social mobility, migration, tourism and education, enhancing intra-European education and mobility policies.";179325,6;179325,6;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;HELSINGIN YLIOPISTO;FI;;;;1;0;0;1;0;0 201175;703733;STILLING;CLOSED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Towards improved understanding of the worldwide decline of wind speed in a climate change scenario;2016-09-01;2018-08-31;;"'In a globally changing climate, scientists have paid little attention on variability of wind speed. A recent discovery to science is the “global stilling'; a worldwide slowdown of wind speed since the 1980s. This stilling is not fully understood and neither the quantity nor the quality of wind speed observations is adequate to allow a reliable study. The scientific aims of this MSCA to fill this key gap are (i) to rescue the longest wind speed series (starting prior to the 1960s), and (ii) to improve our knowledge on the influence of atmospheric circulation. Given the interdisciplinary impacts of 'global stilling' on wind energy, agriculture and hydrology, the socioeconomic-environmental aim is (iii) to look at past wind speed to better assess future wind speed projections needed for climate change adaptation. The innovative approach combines the rescue (ACE framework) and homogenization (SNHT test) of historical wind speed data, providing a unique opportunity to statistically assess trends/cycles and atmospheric causes (SOM/RCPA and weather typing techniques) on long time periods and reliable datasets than previous studies. The applicant will bring his new homogenization protocol, extensive expertise on winds and a novel collaboration topic to UGOT and KNMI. In turn, these Institutions are world authorities on data rescue techniques and attributing causes of climate trends; the applicant will also be trained in leadership, management, funding, supervision and communication skills enhancing his career development. Jointly this team is in a position to push the boundaries of “global stilling” knowledge far ahead, with the ultimate intent to allow the applicant to train through research, establish an independent career, and a research group at the forefront of wind research in Europe. Additionally, this MSCA addresses two of the H2020 Societal Challenges: “Secure, Clean and Efficient Energy”, and “Climate action, Environment, Resource efficiency and Raw materials”.'";185857,2;185857,2;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;GOETEBORGS UNIVERSITET;SE;;;;1;0;0;1;0;0 200837;691058;MOMENDO;SIGNED;H2020-EU.1.3.3.;MSCA-RISE-2015;H2020;Molecular Mechanisms of Endometriosis;2016-01-01;2019-12-31;;Endometriosis (the presence of endometrial-like tissue or ‘lesions’ outside the uterus) is a chronic inflammatory disease affecting 6-10% of reproductive age women. It is associated with pelvic pain, painful periods, pain with sexual intercourse, and subfertility. The socioeconomic impacts of endometriosis are considerable. The recent WERF EndoCost study (a worldwide cost-of-illness study) reported that endometriosis reduced work productivity in 51% and negatively affected relationships in 50% of women with endometriosis. Current treatment options include invasive and repeated surgeries, or hormonal suppression with significant side effects analogous to a premature menopause. While several general concepts of the etiology of the disease such as retrograde menstruation, coelomic metaplasia, lymphovascular metastasis or the embryonic rest theory have been developed, the molecular mechanisms underlying the disease are currently still incompletely understood, hampering the development of efficient targeted therapies with limited side effects. MOMENDO utilizes the potential of an interdisciplinary consortium of leading world endometriosis experts to provide a deeper understanding of key molecular processes contributing to disease etiology and progression. By employing a wide range of experimental methods (biomarker and epigenetic studies on patient tissues, advanced animal models of the disease, proprietary atomic force microscopy for marker-free diagnostics) and novel and innovative conceptual approaches (adult stem cells, microRNAs, iron-induced inflammatory responses, novel endocrine concepts), MOMENDO will substantially contribute to a deeper understanding of the molecular mechanisms that explain the inflammatory pain associated with endometriosis and the persistent growth of endometriosis lesions. By combining the respective strengths of non-academic and clinical partners, MOMENDO expect to successfully translate these findings into novel therapeutic approaches.;346500;346500;H2020-MSCA-RISE-2015;/MSCA-RISE;WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER;DE;"SEREND-IP GMBH;AQUILA BIOMEDICAL LIMITED;CHARITE - UNIVERSITAETSMEDIZIN BERLIN;KAROLINSKA INSTITUTET;TERVISETEHNOLOOGIATE ARENDUSKESKUS AS;THE UNIVERSITY OF EDINBURGH";"DE;UK;SE;EE";;1;0;0;1;0;0 201396;706115;HEAT-WHEAT;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Highly Efficient and Thermotolerant Wheat;2016-09-01;2018-08-31;;"Meeting the needs for a growing food security in a changing climate is currently one the key challenges for agricultural research, particularly the impact of heat waves on food production. Photosynthesis is arguably the greatest contributor to crop yield and its reduction will severely affect food production. Photosynthesis is highly susceptible to even moderately elevated temperatures and susceptibility can be in large part attributed to the enzyme Rubisco activase (RCA), one of the least thermostable photosynthesis proteins and the principal activation partner for the photosynthetic core enzyme Rubisco, that drives carbon fixation and hence growth. Considering the susceptibility of RCA to moderate and severe heat stress and its important role in photosynthesis, the need to improve its thermostability is paramount. In this project, we intend to manipulate RCA in order to enhance the photosynthetic performance, and therefore yield potential, of wheat. We intend to achieve this through sourcing and transfer of heatstable variants of RCA from relatives of wheat that have evolved in hot climates. We will identify the genetic diversity responsible for improving the thermostability of RCA through a combination of comparative bioinformatics, newly developed and refined high throughput Rubisco activation assays. State-of-the-art mutational techniques will be used to further modify wheat RCA to create RCA variants with superior thermostability and optimal activity. Improved variants of wheat RCA will be incorporated into elite wheat germplasm by means of genetic modification and breeding programs. This highly refined, technologically advanced and interdisciplinary approach has the potential to dramatically improve yield production in wheat under future climate scenarios. Furthermore, gains to the technical skill-set and the industrial setting of the research will further the fellow`s objective of having a successful scientific research career in industry.";172800;172800;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;BAYER CROPSCIENCE NV;BE;;;;1;0;0;1;0;0 201494;707253;PopClandSATYRICON;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Popular readers and clandestine literature: the case of an early modern translation of Petronius’ Satyricon into Italian (17th C.);2016-10-01;2018-09-30;;"The project aims at an in-depth inquiry into a 17th-century unpublished manuscript bearing the translation of Petronius’ Satyricon into Italian. The translation represents a unique document, not only because it is likely to be the first version of Petronius into a modern language, but also because it proves the diffusion of the Satyricon even within the public of popular readers. The Satyricon - commonly ascribed to Petronius Arbiter (c. 27-66 AD) - is one of the earliest works classifiable as a novel and is considered a masterpiece of the Latin literature, if not of literature itself. Because of its erotic and irreverent contents, in the age of the Counter-Reformation the Satyricon was included in the list of the books forbidden by the Catholic Church. But, for the very same reason, in the 17th Century, Petronius enjoyed great success among French and Italian libertine élites (freethinkers). Surprisingly enough, the Italian translation proves that Petronius’ forbidden novel also reached un-latined readers. In fact, the material features of the manuscript show that the translation was copied by a professional scribe for clandestine diffusion and that it actually circulated across Italy. Moreover, the quality of the translation shows that its anonymous author was not a person of letters or a scholar, since in several passages he completely misunderstands Petronius’ text. Further, the Italian used by the translator displays regional (Venetian) elements that are far from the Italian literary tradition. The research will be conducted by the means of an interdisciplinary approach, combining the research methods of philology, linguistics, history of the book, history of literature and socio-cultural history. The project will bring a substantial contribution in the field of Early Modern History, showing the emergency of the new public of popular readers and concretely tracking down the circulation of heterodox ideas in the Age of the Counter-Reformation.";185076;185076;H2020-MSCA-IF-2015;/MSCA-IF-EF-CAR;ECOLE DES HAUTES ETUDES EN SCIENCES SOCIALES;FR;;;;1;0;0;1;0;0 200755;681146;ULTRA-SOFC;SIGNED;H2020-EU.1.1.;ERC-CoG-2015;H2020;Breaking the temperature limits of Solid Oxide Fuel Cells: Towards a newfamily of ultra-thin portable power sources;2016-04-01;2021-03-31;;"Solid Oxide Fuel Cells (SOFCs) are one of the most efficient and fuel flexible power generators. However, a great limitation on their applicability arises from temperature restrictions. Operation approaching room temperature (RT) is forbidden by the limited performance of known electrolytes and cathodes while typical high temperatures (HT) avoid their implementation in portable applications where quick start ups with low energy consumption are required. The ULTRASOFC project aims breaking these historical limits by taking advantage of the tremendous opportunities arising from novel fields in the domain of the nanoscale (nanoionics or nano photochemistry) and recent advances in the marriage between micro and nanotechnologies. From the required interdisciplinary approach, the ULTRASOFC project addresses materials challenges to (i) reduce the operation to RT and (ii) technological gaps to develop ultra-low-thermal mass structures able to reach high T with extremely low consumption and immediate start up. A unique ?SOFC technology fully integrated in ultrathin silicon will be developed to allow operation with hydrogen at room temperature and based on hydrocarbons at high temperature. Stacking these ?SOFCs will bring a new family of ultrathin power sources able to provide 100 mW at RT and 5W at high T in a size of a one-cent coin. A stand-alone device fuelled with methane at HT will be fabricated in the size of a dice. Apart from breaking the state-of-the-art of power portable generation, the ULTRASOFC project will cover the gap of knowledge existing for the migration of high T electrochemical devices to room temperature and MEMS to high T. Therefore, one should expect that ULTRASOFC will open up new horizons and opportunities for research in adjacent fields like electrochemical transducers or chemical sensors. Furthermore, new technological perspectives of integration of unconventional materials will allow exploring unknown devices and practical applications.";1841387;1841387;ERC-2015-CoG;/ERC-COG;FUNDACIO INSTITUT DE RECERCA DE L'ENERGIA DE CATALUNYA;ES;;;;1;0;0;1;0;0 200548;682707;ECOHERB;SIGNED;H2020-EU.1.1.;ERC-CoG-2015;H2020;Drivers and impacts of invertebrate herbivores across forest ecosystems globally.;2016-03-01;2021-02-28;;"Forests slow global climate change by absorbing atmospheric carbon dioxide but this ecosystem service is limited by soil nutrients. Herbivores potentially alter soil nutrients in a range of ways, but these have mostly only been recorded for large mammals. By comparison, the impacts of the abundant invertebrates in forests have largely been ignored and are not included in current models used to generate the climate predictions so vital for designing governmental policies The proposed project will use a pioneering new interdisciplinary approach to provide the most complete picture yet available of the rates, underlying drivers and ultimate impacts of key nutrient inputs from invertebrate herbivores across forest ecosystems worldwide. Specifically, we will: (1) Establish a network of herbivory monitoring stations across all major forest types, and across key environmental gradients (temperature, rainfall, ecosystem development). (2) Perform laboratory experiments to examine the effects of herbivore excreta on soil processes under different temperature and moisture conditions. (3) Integrate this information into a cutting-edge ecosystem model, to generate more accurate predictions of forest carbon sequestration under future climate change. The network established will form the foundation for a unique long-term global monitoring effort which we intend to continue long after the current funding time scale. This work represents a powerful blend of several disciplines harnessing an array of cutting edge tools to provide fundamentally novel insights into an area of direct and urgent importance for the society.";1750000;1750000;ERC-2015-CoG;/ERC-COG;LUNDS UNIVERSITET;SE;;;;1;0;0;1;0;0 199952;691238;Bi-Stretch-4-Biomed;SIGNED;H2020-EU.1.3.3.;MSCA-RISE-2015;H2020;BIaxial STRETCHing of PLLA-WS2 nanocomposites FOR thinner and stronger BIOMEDical scaffolds;2016-02-01;2020-01-31;;New materials are now opening clinical treatments in which a temporary scaffold is used to support regeneration of healthy tissue. The specific need that inspires our research is for thinner and stronger bioresorbable vascular scaffolds (BVS) for coronary heart disease. BVS are poised to replace metal stents due to the excellent clinical outcomes: beyond keeping the vessel open during the first six months after surgery, the BVS leaves behind a healthy blood vessel after the scaffold is gone, being completely absorbed by the body approximately two years after surgery. The material that has achieved clinical approval for BVS is poly(L-lactic acid), PLLA. It is not as strong and stiff as metals, so the scaffold is three times thicker than the metal stents, making it more difficult for surgeons to move through arteries to reach the site of the lesion. Thinner Scaffolds that can be seen by x-ray imaging during surgery would facilitate adoption of the technology and benefit thousands of patients in the EU and US. The proposed Action will provide the fundamental understanding needed to reinforce PLLA by tungsten disulphide (WS2) nanotubes to achieve both the strength and x-ray opacity needed. Improving materials for BVS requires an interdisciplinary approach by materials science, polymer processing, and bioengineering. The proposed Action will connect EU scientists with a polymer scientist at Caltech in the US who has specialized knowledge of PLLA BVS and the relevant structure-processing-property relationships (Kornfield). European scientists bring expertise in WS2 nanotubes that are powerful additives for enhancing polymer properties (Di Luccio), compounding polymers with nanotubes (McNally), biaxial stretching to induce strength and orientation in polymers (Menary), multiscale modeling to connect nanoscale to continuum scale (Figiel), multimethod characterization of structure in nanocomposites (Schiller) and the response of cells to nanoparticles (Kornfield).;400500;342000;H2020-MSCA-RISE-2015;/MSCA-RISE;AGENZIA NAZIONALE PER LE NUOVE TECNOLOGIE, L'ENERGIA E LO SVILUPPO ECONOMICO SOSTENIBILE;IT;"THE QUEEN'S UNIVERSITY OF BELFAST;THE UNIVERSITY OF WARWICK";UK;;1;0;0;1;0;0 200138;681891;PROSINT;SIGNED;H2020-EU.1.1.;ERC-CoG-2015;H2020;Multi-protein interaction kinetics by single molecule methods;2016-04-01;2021-03-31;;"Objective of this proposal is to obtain a real time picture of how components of a multi-protein complex interact to perform complex regulated tasks, in particular to see how a protein system might be more than the sum of its components. In living organisms many proteins work in complexes to form multicomponent protein machines and to regulate cellular processes. The function of such multicomponent machines is usually addressed by dividing them into a collection of two state systems at equilibrium. Many molecular machines work in large complexes with multiple states out of equilibrium by utilizing the energy of ATP hydrolysis. In this proposal the real time kinetics of multi-protein interactions in and out of equilibrium will be investigated using single molecule methods. The succession of association and dissociation steps as well as large conformational changes within the proteins will be monitored simultaneously with multicolour single molecule FRET in real time. In order to observe at the same time the folding state of proteins, a combination of optical tweezers and single molecule FRET will be developed. Finally, a combination of microfluidics for fast mixing and single pair FRET will be developed to investigate interactions of low affinity. A large part of the experiments will focus on the example of the heat shock protein Hsp90 system, which consists of co-chaperones, clients and nucleotides. Altogether, these interdisciplinary experiments will yield unprecedented information on multi-component interactions in equilibrium and out of equilibrium on timescales from sub milliseconds to hours. I am confident that these studies will have an impact on the understanding of the Hsp90 machinery as well as general principles of multi-component protein systems, which is the basis for understanding cellular processes.";1882500;1882500;ERC-2015-CoG;/ERC-COG;ALBERT-LUDWIGS-UNIVERSITAET FREIBURG;DE;;;;1;0;0;1;0;0 200710;678042;Token Communities;SIGNED;H2020-EU.1.1.;ERC-StG-2015;H2020;Token Communities in the Ancient Mediterranean;2016-06-01;2021-02-28;;"This project will provide the first comprehensive analysis of the role played by tokens in the ancient Mediterranean. Tokens are frequently found on archaeological sites and within museum collections, but are little studied and poorly understood. These objects played a central role in cultural, religious, political and economic life in antiquity; closer study of these objects is thus imperative in gaining a fuller picture of the ancient world and its cultural legacy. An interdisciplinary team will examine tokens and their contexts within the ancient world, focusing on the periods when they are in highest use: the Hellenistic period (postdoctoral researcher) and the Roman world (PI and 2 PhD students). The project will combine an analysis of museum material with the known archaeological contexts of these objects. It will be the first project to approach these items in a cross regional and fully contextualised manner. This approach will enable researchers to better define what tokens were in antiquity, and what roles they played. Moreover, through a careful consideration of type, context, and distribution, the project will also explore how these objects actively contributed to the generation of different types of community. The envisaged outcomes will provide a basis for the study of tokens more broadly, generating insights that will inform the display, scholarly use and understanding of these objects within museums and other spaces. The exploration of how tokens and token-communities within antiquity existed alongside official currencies and groups will also provide an important historical parallel for the contemporary development of alternative currencies, their associated values, and communities.";1033723;1033723;ERC-2015-STG;/ERC-STG;THE UNIVERSITY OF WARWICK;UK;;;;1;0;0;1;0;0 200162;679924;QINTERNET;SIGNED;H2020-EU.1.1.;ERC-StG-2015;H2020;Quantum communication networks;2016-03-01;2021-02-28;;"My goal is to overcome the two-most pressing theoretical challenges necessary to build large-scale quantum communication networks: routing and designing protocols that use them to solve useful tasks. In two interconnected projects, I will devise entirely new concepts, models and mathematical methods that take into account the intricacies of real world quantum devices that can operate on only very few quantum bits at a time. (1) Security: I will prove the security of quantum cryptographic protocols under realistic conditions, and implement them in collaboration with experimentalists. I will develop a general theory and practical tests for the security of multi-party cryptographic primitives using untrusted quantum devices. This is mathematically challenging due to the possibility of entanglement between the devices. (2) Routing: I will initiate the systematic study of effective routing in a quantum communication network. This is necessary for quantum networks to grow in scale. Quantum entanglement offers very different means of routing messages than is possible in classical networks, and poses genuinely new challenges to computer science. I will design routing protocols in a multi-node quantum network of potentially different physical implementations, i.e., hybrid networks, that will establish a new line of research in my field. Quantum networks are still in their infancy, even though quantum communication offers unparalleled advantages that are provably impossible using classical communication. Building a quantum network is an interdisciplinary effort bringing together computer science, physics, and engineering. I am in a unique position in computer science, since I have recently joined QuTech where I have direct access to small quantum devices - bringing me tantalizingly close to seeing such networks realized. As with early classical networks, it is difficult to predict where our journey will end, but my research will join theory and experiment to move forward.";1498725;1498725;ERC-2015-STG;/ERC-STG;TECHNISCHE UNIVERSITEIT DELFT;NL;;;;1;0;0;1;0;0 201012;702104;COEED;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;The Court of Elizabeth I – A European Drama;2016-10-03;2018-10-02;;"The enduring fascination in anglophone research with the political culture of Elizabethan England has often served to occlude the fact that responses to the Tudor monarch were formulated across renaissance Europe. A pan-European range of dramatic texts bears witness to the anxiety and consuming interest which surrounded Elizabeth I. Such texts have often been neglected or referenced briefly as points of illustration. Moreover, these texts (where afforded any consideration) have most commonly been seen in terms of national traditions of literary production, rather than integrated into a Europe-wide vision of cultural debate and exchange. None of these texts has been considered in recent centuries for their theatrical potential or placed in close conversation with Elizabethan (or post-Elizabethan) literary production. This ambitious comparative project for the early modern period will be achieved through: close & comparative reading of primary texts; evaluative analysis of existing scholarship; consultation of host’s (Institute for Research on the Renaissance, the Neo-classical Age and the Enlightenment - Montpellier 3) and European archives; consultations with supervisor and advisory colleagues across Europe; engagement in performance-related events; e-networking with academic and non-academic audiences. In the course of this European project, Hiscock will: engage in a wholly transformative training in performance-based research and e-dissemination; produce cutting-edge research which embeds multilingual studies at the heart of early modern studies; disseminate research findings to a host of academic and non-academic audiences. This project engages tightly with the Marie Sk³odowska-Curie Programme by: providing professional training in key skills for the applicant, thus enabling him to access significant career progression; investing in wholly innovative interdisciplinary research; enabling international and inter-sector mobility for the applicant.";185076;185076;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;UNIVERSITE PAUL-VALERY MONTPELLIER3;FR;;;;1;0;0;1;0;0 200309;701745;NanoINCAGE;CLOSED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Luminescent Nanocrystals in a Cage for Solar-to-Fuel Conversion;2016-09-01;2018-08-31;;Artificial photosynthesis, which can produce hydrogen and oxygen from solar irradiation, is one of the possible means to provide clean and renewable energy. Despite the recent progress, this emerging field is challenged by huge technical and scientific questions. In natural photosynthesis light absorption and catalysis occur in different sites of the leaf. In a simplified scenario, the energy harvested by the light absorbing pigments is funnelled towards the oxygen evolving complex. Here, we propose to realize the same biologically-inspired scheme using a novel hybrid system consisting of colloidal quantum dots embedded in a metal organic framework cage (CQD@MOF). In particular, a CQD Förster-transfer based light harvesting antenna will directionally transfer energy to a catalyst located in separate sites of the device. In addition to the rich basic science opportunities behind the introduction of this new concept in artificial photosynthesis, full-solar spectrum harvesting deriving from the characteristic size-dependent band gap tunability of CQDs, the potential for high voltages by combining CQDs of different size and composition, and the lack of contact between the light absorber and the electrolyte, intrinsic to the proposed device architectures, are all advantages that make this CQD@MOF hybrid Förster-based scheme highly appealing. One of the key component of the research will be to develop synthetic schemes to access these multifunctional systems with an unprecedented level of control through multiple length-scales. The experience and the skills gained by the applicant during her earlier carrier in the device fabrication together with the long-standing experience of the supervisor in this field will be extremely beneficial for a successful outcome of the proposal.NanoINCAGE is highly multidisciplinary and interdisciplinary program and its successful outcome will tremendously impact several other research fields in chemistry, materials science and engineering.;175419,6;175419,6;H2020-MSCA-IF-2015;/MSCA-IF-EF-RI;ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE;CH;;;;1;0;0;1;0;0 200288;677912;EUROPIUM;SIGNED;H2020-EU.1.1.;ERC-StG-2015;H2020;The origin of heavy elements: a nuclear physics and astrophysics challenge;2016-05-01;2021-04-30;;Where in the universe are heavy elements synthesized? How are these elements produced? These are two exciting and interdisciplinary questions in nuclear astrophysics today and will be investigated in my ERC project EUROPIUM. The favored astrophysical sites are neutrino-driven winds following core-collapse supernovae and neutron star mergers, where extreme conditions enable the rapid neutron capture process (r-process). We will perform long-time multidimensional simulations of these two scenarios and combine them with nucleosynthesis calculations. In neutron star mergers, the radioactive decay of neutron-rich nuclei triggers an electromagnetic signal known as kilonova. This was potentially observed in 2013 after a short gamma ray burst, associated with a neutron star merger. We will simulate the neutrino- and viscous-driven ejecta from the disk that forms after the merger around the central compact object. In addition, we will investigate supernova neutrino-driven winds that produce lighter heavy elements from strontium to silver. We will explore the impact of rotation, improved microphysics, and magnetic fields on the wind evolution and nucleosynthesis. Because the synthesis of lighter heavy elements elements occurs closer to stability, the nuclear physics uncertainties will be reduced by experiments in the near future. This will uniquely allow us to combine observations and nucleosynthesis calculations to constrain the astrophysical conditions and gain new insights into core-collapse supernovae. In nuclear physics, a new era for extreme neutron-rich isotopes is starting with new experimental facilities. Based on our simulations, we will study the impact of the nuclear physics input (nuclear masses, beta decays, neutron captures, and fission) going beyond the state-of-the-art by providing r-process abundances with uncertainties. Comparing our results with forefront observations of the oldest stars will in turn provide new insights about the origin of heavy elements.;1446875;1446875;ERC-2015-STG;/ERC-STG;TECHNISCHE UNIVERSITAT DARMSTADT;DE;;;;1;0;0;1;0;0 199937;691053;ODYSSEA;SIGNED;H2020-EU.1.3.3.;MSCA-RISE-2015;H2020;OBSERVATORY OF THE DYNAMICS OF INTERACTIONS BETWEEN SOCIETIES AND ENVIRONMENT IN THE AMAZON;2016-01-01;2019-12-31;;"Achieving a sustainable development trajectory in Amazonia is one of the key challenges facing Brazil, and is also an important international concern. ODYSSEA assembles an internationally renowned European and Brazilian multidisciplinary and intersectoral team. We aim to produce fundamental science and tools in order to build an innovative multi-and interdisciplinary observatory to monitor and assess dynamic interactions between Amazon societies and their environments. This observatory will serve as a basis for policy development that integrates social, environmental, political-economic and human health dimensions. Our methodology puts the society at the heart of the observatory’s building process, engaging stakeholders and decision makers in the research to favour advancement of their objectives and commitment to sustainable development issues. Building on knowledge framed around ongoing bilateral projects, ODYSSEA brings together several independent networks of international and Brazilian researchers which all have long-term experiences in the Amazon of environmental and social research, each with their own expert skill-sets. We expect significant advances in our understanding of the different feedbacks and linkages between the panoply of pressures exerted on the environment, the factors determining the vulnerability of local populations to environmental shocks and in the evaluation of governance and institutional arrangements aiming at promoting adaptation. We aim to enhance the capacity of Brazilian institutions to assess and reduce the vulnerability of populations in Amazonia. ODYSSEA will help unify an increasing number of bilateral arrangements for research and innovation between individual European countries and Brazil. Whilst these connections are proving fruitful in their own right there is a largely untapped opportunity to upscale the intensity and diversity of connections between Europe and Brazil on all levels of education, research and development.";1849500;1705500;H2020-MSCA-RISE-2015;/MSCA-RISE;INSTITUT DE RECHERCHE POUR LE DEVELOPPEMENT;FR;"VIEIRA PAK MANUELA;UNIVERSITE DE GUYANE;INSTITUTO SUPERIOR DE AGRONOMIA;UNIVERSITE DE MONTPELLIER;STIFTELSEN THE STOCKHOLM ENVIRONMENT INSTITUTE;UNIVERSITE RENNES II;LANCASTER UNIVERSITY;CENTRE DE COOPERATION INTERNATIONALE EN RECHERCHE AGRONOMIQUE POUR LEDEVELOPPEMENT - C.I.R.A.D. EPIC;UNIVERSITAET INNSBRUCK;UNIVERSITE PAUL SABATIER TOULOUSE III;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;GEOMATYS;LISODE SARL";"FR;PT;SE;UK;AT";;1;0;0;1;0;0 197841;639270;SYMCAR;SIGNED;H2020-EU.1.1.;ERC-StG-2014;H2020;Symbolic Computation and Automated Reasoning for Program Analysis;2016-04-01;2021-03-31;;"Individuals, industries, and nations are depending on software and systems using software. Automated approaches are needed to eliminate tedious aspects of software development, helping software developers in dealing with the increasing software complexity. Automatic program analysis aims to discover program properties preventing programmers from introducing errors while making changes and can drastically cut the time needed for program development. This project addresses the challenge of automating program analysis, by developing rigorous mathematical techniques analyzing the logically complex parts of software. We will carry out novel research in computer theorem proving and symbolic computation, and integrate program analysis techniques with new approaches to program assertion synthesis and reasoning with both theories and quantifiers. The common theme of the project is a creative development of automated reasoning techniques based on our recently introduced symbol elimination method. Symbol elimination makes the project challenging, risky and interdisciplinary, bridging together computer science, mathematics, and logic. Symbol elimination will enhance program analysis, in particular by generating polynomial and quantified first-order program properties that cannot be derived by other methods. As many program properties can best be expressed using quantified formulas with arithmetic, our project will make a significant step in analyzing large systems. Since program analysis requires reasoning in the combination of first-order logic and theories, we will design efficient algorithms for automated reasoning with both theories and quantifiers. Our results will be supported by the development of world-leading tools supporting symbol elimination in program analysis. Our project brings breakthrough approaches to program analysis, which, together with other advances in the area, will reduce the cost of developing safe and reliable computer systems used in our daily life.";1500000;1500000;ERC-2014-STG;/ERC-STG;TECHNISCHE UNIVERSITAET WIEN;AT;;;;1;0;0;1;0;0 197872;648608;EXCHANGE;SIGNED;H2020-EU.1.1.;ERC-CoG-2014;H2020;Forensic Geneticists and the Transnational Exchange of DNA data in the EU: Engaging Science with Social Control, Citizenship and Democracy;2015-10-01;2020-09-30;;"Today we are living in the “genetic age” of criminal investigation. There is a widespread cultural belief that DNA technology has the unrivalled capacity to identify authors of crimes. In light of this ideology, EU Law (Prüm Decision, 2008) obliges all Member States to create the conditions for the reciprocal automated searching and comparison of information on DNA data for the purpose of combating cross-border crime, terrorism and illegal immigration. Forensic geneticists play a crucial role in this scenario: they develop the techno-scientific procedures that enable DNA data to be shared across national boundaries. EXCHANGE aims to understand the close links between a highly specialised field of expert knowledge – forensic genetics – and surveillance in the EU. If the EU succeeds in this political project, about 10 million genetic profiles of identified individuals will be exchanged between agencies in all EU countries. This raises acute cultural, political and societal challenges. EXCHANGE aims to address these challenges by scrutinizing how forensic geneticists, within the context of the transnational exchange of DNA data in the EU, engage with the social values attributed to science – i.e. objectivity, truth – and the values of social control, citizenship and democracy. The expected outputs are: 1. To provide a general picture of the Prüm framework by conducting interviews with forensic geneticists in all EU countries; 2. To develop in-depth knowledge of forensic geneticists’ activities relating to Prüm using ethnographic observation and qualitative analysis of criminal cases; 3. To study countries with different local positionings in relation to Prüm by means of a comparative study involving Portugal, Germany, the Netherlands and the UK. EXCHANGE stimulates interdisciplinary dialogue between the social sciences and the forensic genetics. This research also tackles questions that are relevant to all the actors involved in criminal justice cooperation in the EU.";1838150;1838150;ERC-2014-CoG;/ERC-COG;CENTRO DE ESTUDOS SOCIAIS;PT;;;;1;0;0;1;0;0 197906;665860;SoMoPro 3;SIGNED;H2020-EU.1.3.4.;MSCA-COFUND-2014-FP;H2020;South Moravian Programme for Distinguished Researchers 3;2015-09-01;2020-08-31;;"SoMoPro 3 is an innovated regional fellowship programme building on its two predecessors, SoMoPro (2009–2013) and SoMoPro II (2012–2017). The program was established in 2009 after a successful application to the COFUND scheme. Since then 4 calls for proposals have been open: in 2009, 2010 and 2012, 2013 with 53 fellowships funded. The objective of this application is to launch 2 more calls and support 20 more fellows. SoMoPro 3 incorporates main features of MSCA and offers incoming researchers attractive conditions and environment (e.g. state-of-the-art equipment in newly build infrastructures). Its aim is to foster international mobility, attract high-quality researchers, provide them training and career development and boost the growing innovation activities in the South Moravian Region. The programme combines extensive experience enriched with new qualitative features – research topics in line with domains defined in regional S3 (while emphasising interdisciplinary approaches), closer interaction with key industrial players based in the region (offering researchers an opportunity to gain intersectoral experience) and modified administrative procedures (to allow greater flexibility and decrease the administrative burden). The reason to apply for another COFUND is not only the financial contribution which will enable to fund the fellows (as there is no such funding available on the Czech national level). It is also the fact that it increases international recognition of the programme and provides a well known “mark of quality”. It is for the benefit of the researchers, who become Marie Sk³odowska-Curie fellows, of the regional host institutions, which profit from hosting high-quality researchers as well as of the region itself as it profits from interaction between high-quality researchers and key industrial players.";3658000;1829000;H2020-MSCA-COFUND-2014;/MSCA-COFUND-FP;Region of South Moravia;CZ;;;;1;0;0;1;0;0 198065;647938;LEGO;SIGNED;H2020-EU.1.1.;ERC-CoG-2014;H2020;Multimodal glycoconjugates: a molecular Lego approach for antitumoral immunotherapy;2015-09-01;2020-08-31;;Despite significant progress in cancer therapy, current treatments are still controversial due to intolerable side effects. Targeted immunotherapy has recently emerged as an ideal alternative to improve treatment modalities for cancers patients. However, very limited approaches are available today and major issues remain to be addressed. The ERC grant offers a unique opportunity to propose a new paradigm for treating cancer. Through a ground-breaking interdisciplinary program, at the crossroad of supramolecular chemistry, synthetic chemistry, molecular engineering, biophysics, biochemistry, immunochemistry and glycoscience, it is my ambition to design, synthesize and study smart biomolecular structures with unprecedented combinations, complexity and immunological properties against cancers. To achieve this purpose, I will develop a “molecular LEGO” approach to construct synthetic molecules capable of redirecting endogenous antibodies present in the human bloodstream against tumors without preliminary immunization. Efficient tumoral killing by immune effectors will be provided by molecules combining innovative antibody and tumor binding modules that will be selected in vitro beforehand. To be successful, I will address fundamental questions that are still unresolved in chemical and biological sciences. The expected breakthroughs will represent a landmark achievement in these fields and will open promising horizons in cancer immunotherapy. Beyond this, it can be expected that our findings will pave the way to future development of synthetic molecules embedded with recognition, labeling, and/or therapeutic functions. They will thus find wider medicinal, diagnostic and even theranostic applications for which the development of more effective and selective biomolecular systems is of the utmost importance.;2000000;2000000;ERC-2014-CoG;/ERC-COG;UNIVERSITE JOSEPH FOURIER GRENOBLE 1;FR;;;;1;0;0;1;0;0 198107;675228;CaSR Biomedicine;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2015-ETN;H2020;Calcium-Sensing Receptor (CaSR): Therapeutics for Non-Communicable Diseases;2016-03-01;2020-02-29;;"The calcium sensing receptor (CaSR) is a class C Gprotein-coupled receptor that plays a pivotal role in systemic calcium metabolism by regulating parathyroid hormone secretion and urinary Ca excretion. Abnormal CaSR function is implicated in calciotropic disorders, and in non-calciotropic disorders such as Alzheimer’s disease (AD), cardiovascular disease (CVD), diabetes (DM), sarcopenia and cancer, which account for >25% of the global disease burden. The CaSR is a unique GPCR whose principal physiological ligand is the Ca2\ ion; it is expressed almost ubiquitously; interacts with multiple G? subtypes regulating highly divergent downstream signalling pathways, depending on the cellular context. The CaSR Biomedicine is a fully translational project that utilises the concept of a single molecule, the CaSR, influencing a range of physiological and disease processes, to develop a unique, strong multidisciplinary and intersectoral scientific training programme preparing 14 young scientists to become specialists in GPCR biology and signalling. The objectives of CaSR Biomedicine are: 1. Educate and train Early Stage Researchers to become highly innovative scientists to enhance their career perspective. 2. Elucidate ligand- and tissue-dependent differences in CaSR physiology by examining its functions at cellular level and thus to contribute to the understanding of GPCR signalling in general; 3. Assess how CaSR function is altered in AD, CVD, DM, sarcopenia, and cancer, and to find innovative CaSR-based therapeutic approaches for these major, age-related disorders. 4. Establish long-lasting interdisciplinary and intersectoral cooperation among researchers and between researchers and industry, to strengthen the European Research Area. Therefore the CaSR Biomedicine will investigate the complexity of CaSR signalling and function to identify CaSR-based therapeutic approaches to diseases linked to changes in CaSR expression or function (AD, CVD, DM, sarcopenia, and cancer).";3657194,64;3657194,64;H2020-MSCA-ITN-2015;/MSCA-ITN-ETN;MEDIZINISCHE UNIVERSITAET WIEN;AT;"S.A.F.AN. BIOINFORMATICS - SAS DI PUGLIESE LUISA;UNIVERSITE DE PICARDIE JULES VERNE;FUNDACIO SANT JOAN DE DEU;THE UNIVERSITY OF MANCHESTER;STICHTING VU;UNIVERSITA DEGLI STUDI DI FIRENZE;KOBENHAVNS UNIVERSITET;BIOTALENTUM TUDASFEJLESZTO KFT;TISSUEGNOSTICS GMBH;THE UNIVERSITY OF LIVERPOOL;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;CARDIFF UNIVERSITY";"IT;FR;ES;UK;NL;DK;HU;AT";;1;0;0;1;0;0 199191;690836;PANG;SIGNED;H2020-EU.1.3.3.;MSCA-RISE-2015;H2020;Pathogen and Graphene;2016-01-01;2019-12-31;;"Complications related to infectious diseases have significantly reduced, particularly in the developed countries, due to the availability and use of broad-range antibiotics and wide variety of antimicrobial agents. Excessive use of antibiotics and antimicrobial agents increased significantly the number of multi-drug resistant (MDR) bacteria. This has resulted in a serious threat to public health. The inexorable rise in the incidence of antibiotic resistance in bacterial pathogens, coupled with the low rate of emergence of new clinically useful antibiotics, has refocused attention on finding alternatives to overcome antimicrobial resistance. Novel strategies aiming to reduce the amount of antibiotics, but able to prevent and treat animal and human infections should be investigated, evidenced and approved. Among the various approaches, the use of graphene and its derivatives is currently considered a highly promising strategy to overcome microbial drug resistance. In line with this interest in graphene by the European Commission through the graphene ‘flagship’ initiatives, we respond in this consortium by exploring the utility of novel graphene based nanocomposites for the management and better understanding of microbial infections. The anti-microbical potential of the novel graphene based nanomaterials, the possibility of using such structures for the development of non-invase therapies together with the understanding of the mechanism of action will be the main focal points of the proposed project entitled “PANG”, relating to Pathogen and Graphene. We have gathered the essential elements, namely different academic institutions in Europe (France, Germany, and Sweden) and their associated countries (Ukraine) as well as two European companies (Graphenea-Spain and LSO Medical-France) and one company (RS RESEARCH) in one of the associated countries (Turkey). The proposed multidisciplinary project uniquely suits high-level interdisciplinary and cross-border training.";580500;580500;H2020-MSCA-RISE-2015;/MSCA-RISE;UNIVERSITE DE LILLE;FR;"RS ARASTIRMA EGITIM DANISMANLIK ILAC SANAYI TICARET LIMITED SIRKETI;LSO MEDICAL;GRAPHENEA SA;RUHR-UNIVERSITAET BOCHUM;LVIVSKYI NATIONALNYI MEDYCHNYI UNIVERSYTET IMENI DANYLA HALYTSKOHO;UNIVERSITATSKLINIKUM ERLANGEN;GOETEBORGS UNIVERSITET";"TR;FR;ES;DE;UA;SE";;1;0;0;1;0;0 198315;675997;MARmaED;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2015-ETN;H2020;MARine MAnagement and Ecosystem Dynamics under climate change;2015-10-01;2019-09-30;;"The proposed European Training Network, MARmaED, connects science, policy and people and transcends national borders, disciplinary barriers and sectorial divides. By building a greater knowledge base and train the next generation of scientists to think across disciplines, MARmaED contributes to reinforce Europe’s position as a global leader in marine science and ensure blue growth and sustainable exploitation of marine living resources. The objectives of MARmaED are: - To increase the marine scientific knowledge base by integrating traditionally separate scientific disciplines within a unified learning platform. - To train a new generation of innovative researchers with interdisciplinary experience and skilled in promoting marine science to a wide audience. MARmaED integrates education and research in complementary marine sciences in Norway, Finland, Denmark, the Netherlands, Germany and France. Specifically, the network links state-of-the-art competences in genetics, ecophysiology, ecology, climatology, physical oceanography, statistics and economics. By so doing, the network unifies essential disciplines needed to achieve a good understanding and management of the marine environment. The research will provide new insights into how the cumulative stress from biodiversity loss, climate change and harvesting affects Europe’s complex marine systems and the consequences for optimal resource use - knowledge that is needed for sustainable, ecosystem-based management. MARmaED has a strong focus on training, with a mobility programme facilitating inter-disciplinarity and training modules of transferrable skills such as communication. Targeted secondments in the non-academic sector will provide the network’s students with inter-sectorial training and favourable employment opportunities. MARmaED will thus create novel standards in the training of a new generation of multi-disciplinarily skilled and creative marine scientists, fit to address Europe’s future challenges.";4073903,28;4073903,28;H2020-MSCA-ITN-2015;/MSCA-ITN-ETN;UNIVERSITETET I OSLO;NO;"HELSINGIN YLIOPISTO;UNIVERSITAET HAMBURG;DANMARKS TEKNISKE UNIVERSITET;METEO-FRANCE;WAGENINGEN UNIVERSITY;ABO AKADEMI;UNIVERSITETET I BERGEN";"FI;DE;DK;FR;NL;NO";;1;0;0;1;0;0 198615;647121;PLASMA;SIGNED;H2020-EU.1.1.;ERC-CoG-2014;H2020;Running away and radiating;2015-10-01;2020-09-30;;Particle acceleration and radiation in plasmas has a wide variety of applications, ranging from cancer therapy and lightning initiation, to the improved design of fusion devices for large scale energy production. The goal of this project is to build a flexible ensemble of theoretical and numerical models that describes the acceleration processes and the resulting fast particle dynamics in two focus areas: magnetic fusion plasmas and laser-produced plasmas. This interdisciplinary approach is a new way of studying charged particle acceleration. It will lead to a deeper understanding of the complex interactions that characterise fast particle behaviour in plasmas. Plasmas are complex systems, with many kinds of interacting electromagnetic (EM) waves and charged particles. For such a system it is infeasible to build one model which captures both the small scale physics and the large scale phenomena. Therefore we aim to develop several complementary models, in one common framework, and make sure they agree in overlapping regions. The common framework will be built layer-by-layer, using models derived from first principles in a systematic way, with theory closely linked to numerics and validated by experimental observations. The key object of study is the evolution of the velocity-space particle distribution in time and space. The main challenge is the strong coupling between the distribution and the EM-field, which requires models with self-consistent coupling of Maxwell’s equations and kinetic equations. For the latter we will use Vlasov-Fokker-Planck solvers extended with advanced collision operators. Interesting aspects include non-Maxwellian distributions, instabilities, shock-wave formation and avalanches. The resulting theoretical framework and the corresponding code-suite will be a novel instrument for advanced studies of charged particle acceleration. Due to the generality of our approach, the applicability will reach far beyond the two focus areas.;1948750;1948750;ERC-2014-CoG;/ERC-COG;CHALMERS TEKNISKA HOEGSKOLA AB;SE;;;;1;0;0;1;0;0 198281;675265;OMA;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2015-ETN;H2020;Optimization of Medical Accelerators;2016-02-01;2020-01-31;;"Cancer is a major social problem, and it is the main cause of death between the ages 45-65 years. In the treatment of cancer, radio therapy (RT) plays an essential role. RT with hadrons (protons and light ions), due to their unique physical and radiobiological properties, offers several advantages over photons for specific cancer types. In particular, they penetrate the patient with minimal diffusion, they deposit maximum energy at the end of their range, and they can be shaped as narrow focused and scanned pencil beams of variable penetration depth. Although significant progress has been made in the use of particle beams for cancer treatment, an extensive research and development program is still needed to maximize the healthcare benefits from these therapies. The Optimization of Medical Accelerators (OMA) is the aim of the here-proposed European Training Network, in line with the requirements of the EC’s Medical Exposure Directive. OMA joins universities, research centers and clinical facilities with industry partners to address the challenges in treatment facility design and optimization, numerical simulations for the development of advanced treatment schemes, and in beam imaging and treatment monitoring. The proposed R&D program ranges from life sciences (oncology, cell and micro biology and medical imaging.), physics and accelerator sciences, mathematics and IT, to engineering. It is hence ideally suited for an innovative training of early stage researchers. By closely linking all above research areas, OMA will provide an interdisciplinary education to its Fellows. This will equip them with solid knowledge also in research areas adjacent to their core research field, as well as with business competences and hence give them a perfect basis for a career in research.";3871703,52;3871703,52;H2020-MSCA-ITN-2015;/MSCA-ITN-ETN;THE UNIVERSITY OF LIVERPOOL;UK;"LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN;FONDAZIONE CENTRO NAZIONALE DI ADROTERAPIA ONCOLOGICA;THE UNIVERSITY OF MANCHESTER;ION BEAM APPLICATIONS SA;GSI HELMHOLTZZENTRUM FUER SCHWERIONENFORSCHUNG GMBH;AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS;AMSTERDAM SCIENTIFIC INSTRUMENTS BV;EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH;PAUL SCHERRER INSTITUT;VIALUX MESSTECHNIK + BILDVERARBEITUNG GMBH;EBG (Entwicklungs- und Betriebsgesellschaft) MedAustron GmbH;UNIVERSITY COLLEGE LONDON;UNIVERSIDAD DE SEVILLA";"DE;IT;UK;BE;ES;NL;CH;AT";;1;0;0;1;0;0 198298;675546;MicroArctic;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2015-ETN;H2020;Microorganisms in Warming Arctic Environments;2016-04-01;2020-03-31;;The Arctic plays a key role in the Earth’s climate system and is an area of growing strategic importance for European policy. In this ETN, we will train the next generation of Arctic microbiology and biogeochemistry experts who, through their unique understanding of the Arctic environment and the factors that impact ecosystem and organism response to the warming Arctic, will be able to respond to the need for leadership from public, policy and commercial interests. The training and research programme of MicroArctic is made up of seven interlinked Work Packages (WP). WP1 to WP4 are research work packages at the cutting edge of Arctic microbiology and biogeochemistry and these will be supported by three overarching WPs (WP5-7) associated with the management, training and dissemination of results. WP1 will deliver information about the role of external inputs (e.g., atmospheric) of nutrients and microorganism that drive biogeochemical processes in relation to annual variation in Arctic microbial activity and biogeochemical processes. WP2 will explore ecosystem response on time scales of 100s of years to these inputs using a chrnosequence approach in the already changing Arctic. The effect of time and season and the warming of the Arctic on ecosystem functioning and natural resources will be quantified through geochemical analyses and next generation multi-omics approaches. Complementing WP1 and WP2, WP3 will focus on organism response and adaptation using a range of biochemical, molecular, experimental and culturing approaches. WP4 will address specific applied issues such as colonisation by pathogenic organisms and biotechnological exploitation of Arctic ecosystems. MicroArctic will bring together interdisciplinary experts from both the academic and non-academic sectors across Europe into a network of 20 Institutions across 11 countries.;3897006,48;3897006,48;H2020-MSCA-ITN-2015;/MSCA-ITN-ETN;UNIVERSITY OF BRISTOL;UK;"HASKOLINN A AKUREYRI;ENOVEO SARL;DR. BRILL + PARTNER GMBH INSTITUT FUER HYGIENE UND MIKROBIOLOGIE;MBIOINFORM APS;HELMHOLTZ ZENTRUM POTSDAM DEUTSCHESGEOFORSCHUNGSZENTRUM GFZ;UNIVERSITY OF NORTHUMBRIA AT NEWCASTLE;INSTITUTUL DE BIOLOGIE BUCURESTI;EIDGENOESSISCHE FORSCHUNGSANSTALT WSL;ECOLE CENTRALE DE LYON;ABERYSTWYTH UNIVERSITY;UNIVERSITAET INNSBRUCK;UNIVERZA V LJUBLJANI";"IS;FR;DE;DK;UK;RO;CH;AT;SI";;1;0;0;1;0;0 198260;674962;SUSPLACE;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2015-ETN;H2020;SUSPLACE;2015-10-01;2019-09-30;;"SUSPLACE will train 15 ESRs in sustainable place-shaping by 1) its cutting edge scientific knowledge and methodologies 2) enhancing transferable skills 3) supporting a career development plan and 4) expose ESRs to science, public administration and governance, private businesses, NGOs and citizens initiatives. This will create career prospects for ESRs as an academic, policy-maker or policy-advisor, private business consultant or intermediate between various stakeholders in collaborative sustainable place-shaping projects. SUSPLACE consists of 6 academic beneficiaries and 7 non-academic partners. Training will include training-through research, joint training and events, optional courses, and 'on the job' training during secondments. SUSPLACE supports ESRs to complete a PhD-thesis. SUSPLACE will raise capacities to implement place-specific, integrative solutions via 15 individual research projects, divided along five interconnected research themes: inclusive, resilient and connected places, greening economies, and pathways to sustainability. SUSPLACE will share its outcomes with non-participants via a range of training, communication and dissemination activities. The integrative place-based approach of SUSPLACE will take up the societal challenges formulated in the EU Territorial Agenda 2020, and contribute to smart, sustainable and inclusive growth and social innovation, to enhance social cohesion. SUSPLACE will provide insights and means how to fully utilize the potential of places and communities via interdisciplinary research in places and Living Labs. Sustainable place-shaping will strengthen the participation, collaboration, collective agency and leadership of people engaged in these places. Sustainable place-shaping entails a well-balanced: 1) socio-cultural re-appreciation of respective places; 2) ecological re-grounding of practices in place-specific assets and resources; 3) political-economic re-positioning towards markets, technology and policies.";3818410,56;3818410,56;H2020-MSCA-ITN-2015;/MSCA-ITN-ETN;WAGENINGEN UNIVERSITY;NL;"LUONNONVARAKESKUS;UNIVERSIDADE DE AVEIRO;LATVIJAS UNIVERSITATE;KATHOLIEKE UNIVERSITEIT LEUVEN;CARDIFF UNIVERSITY";"FI;PT;LV;BE;UK";;1;0;0;1;0;0 198505;675071;ISOTOPICS;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2015-ETN;H2020;ISOTOPIC LABELING FOR DRUG INNOVATION;2016-01-01;2019-12-31;;"Excessive attrition rates during clinical trials dramatically impact on Drug Discovery and Development (DDD). Absorption, Distribution, Metabolism and Excretion studies carried out on larger series of drug candidates at an earlier stage of the DDD timeline and evaluation of drug efficacy through better assessment of pharmacokinetic/pharmacodynamic relationships, target engagement and receptor occupancy are critically important approaches for de-risking drug innovation since they facilitate early identification of the candidates that display the best in vivo profile. When successfully implemented, this strategy can accelerate the discovery of new therapeutic solutions to existing and emerging diseases, and enhance European pharmaceutical innovation. For implementation, large sets of isotopically-labeled molecules are required and consequently, a huge revival of labeling techniques is urgently needed. Another crucial issue is the scarcity of expert radiochemists in Europe and the lack of first class training programs in this inter-disciplinary field merging chemistry, radiochemistry and medicinal chemistry. The aims of ISOTOPICS are: i) to train the next generation of European chemists with expertise in isotopic labeling and advanced medicinal chemistry through a first-class taught and research training program combined with a highly interactive secondments plan; ii) to develop innovative and general isotopic labeling chemistry and radiochemistry to streamline the synthesis of labeled small-molecule drugs and biologics; iii) to work closely with the European pharmaceutical industry to apply the new labeling methods to drugs currently in development in order to provide solutions to the most pressing problems in drug innovation. This highly interdisciplinary project is expected to have a profound beneficial impact on drug innovation in Europe by providing novel efficient techniques and new experts in the fields of labeling and medicinal chemistries.";3948843,96;3948843,96;H2020-MSCA-ITN-2015;/MSCA-ITN-ETN;COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES;FR;"UNIVERSITE DE LIEGE;SANOFI-AVENTIS DEUTSCHLAND GMBH;UCB BIOPHARMA SPRL;UCB PHARMA SA;ASTRAZENECA AB;KAROLINSKA INSTITUTET;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS";"BE;DE;SE;UK;FR";;1;0;0;1;0;0 198619;647315;GlassRoutes;SIGNED;H2020-EU.1.1.;ERC-CoG-2014;H2020;Mapping the First Millennium Glass Economy;2015-10-01;2020-09-30;;"The production of raw glass up until the early medieval period was restricted to few primary glassmaking centres in the Levant and Egypt producing glasses with distinct chemical fingerprints that were then shipped all over the Mediterranean. The study of glass thus provides a unique perspective on long-distance communications and shifts in economy, trade and cultural interactions. This project explores the production, trade and consumption of glass as a major economic activity in the medieval Mediterranean. The chronological parameters are the 4th to 12th centuries CE, covering a period of significant diversification and technological innovations in glass production. The project addresses three broad gaps in our understanding of these developments: Byzantine glassmaking; the spread of Islamic plant ash glass; and the role of the Iberian peninsula. GlassRoutes will push the frontiers of glass research by integrating chemical, archaeological and documentary data about these three key players in the medieval glass economy. By comparing the material and artistic aspects of glass assemblages from selected Mediterranean sites it will identify patterns in the manufacture, trade and usage of glass. The aim of GlassRoutes is to establish the socio-cultural and geopolitical dimensions of glass. What types of primary (raw) glass are found at different sites? How do they compare in terms of secondary use (types of artefacts)? What are the reasons for the differential use of glass and its colours? Research will examine the provenance of the material in relation to its use for selected artefacts to reveal the economic and cultural mechanisms underlying the culture-specific use of glass. This project is unique in its interdisciplinary approach; it combines archaeological, historical and analytical data as well as statistic tools to characterise the dynamic relationship between supply and consumption and its implications for artistic practices and technological innovation.";1982401;1982401;ERC-2014-CoG;/ERC-COG;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FR;;;;1;0;0;1;0;0 196834;645677;SMART GEMS;SIGNED;H2020-EU.1.3.3.;MSCA-RISE-2014;H2020;Smart Grids Energy management Staff;2015-09-01;2019-08-31;;"Smart grid is a dynamically interactive real-time infrastructure concept that encompasses the many visions of diverse energy system stakeholders. The Smart Grid is integrating the electrical and information technologies in between any point of generation and any point of consumption. The main objective of the project is to fully analyze all aspects of smart grids targeting in the improvement of reliability, mitigation of security risks, increase load shaping and energy efficiency, optimal integration and generation-consumption matching as well as smart monitoring and control. To this end, the aim of the SMART GEMS project is to use Smart Grids’ optimization and reliable operation concept as the common basis for collaboration and staff exchange among the partners. The overall effort will be based in two existing smart grid infrastructures owned by TUC and AEA and is designed to exploit the complementary expertise of the participants as well as enhance and create more synergies. Moreover the infrastructure of all partners will be available for the project’s goals. In this framework, SMART-GEMS partners are selected to formulate a complementary group which encompasses all the major aspects of smart grids. During the SMART GEMS secondments, a mixture of research and training will be blended in a suitable proportion as to maximize the career perspectives of the researchers involved focusing on innovation skills related to smart grids and smart communities interdisciplinary aspects. The methodological approach is designed to enhance the researchers’ competitiveness and promote the ideas sharing from research to market and vice versa. The methodology is based on a cycle expansion in three dimensions where all participants are actively involved";1012500;958500;H2020-MSCA-RISE-2014;/MSCA-RISE;POLYTECHNEIO KRITIS;EL;"AEA s.r.l.;TECHNOLOGIKO PANEPISTIMIO KYPROU;IDEA SRL;ETHNIKO KAI KAPODISTRIAKO PANEPISTIMIO ATHINON;THE UK INTELLIGENT SYSTEMS RESEARCH INSTITUTE LIMITED;EXERGY LTD;BRUNEL UNIVERSITY LONDON;REGENERA LEVANTE SL;Elgama-Elektronika;THE CYPRUS INSTITUTE;UNIVERSITA DELLA CALABRIA";"IT;CY;EL;UK;ES;LT";;1;0;0;1;0;0 197097;646857;ECLAIR;SIGNED;H2020-EU.1.1.;ERC-CoG-2014;H2020;Emulation of subgrid-scale aerosol-cloud interactions in climate models: towards a realistic representation of aerosol indirect effect;2015-09-01;2020-08-31;;"I propose to develop an innovative interdisciplinary model framework to refine the estimate of aerosol indirect effect (i.e. influence of atmospheric aerosol particles on cloud properties), which remains the single largest uncertainty in the current drivers of climate change. A major reason for this uncertainty is that current climate models are unable to resolve the spatial scales for aerosol-cloud interactions. We will resolve this scale problem by using statistical emulation to build computationally fast surrogate models (i.e. emulators) that can reproduce the effective output of a detailed high-resolution cloud-resolving model. By incorporating these emulators into a state-of-the-science climate model, we will for the first time achieve the accuracy of a limited-area high-resolution model on a global scale with negligible computational cost. The main scientific outcome of the project will be a highly refined and physically sound estimate of the aerosol indirect effect that enables more accurate projections of future climate change, and thus has high societal relevance. In addition, the developed emulators will help to quantify how the remaining uncertainties in aerosol properties propagate to predictions of aerosol indirect effect. This information will be used, together with an extensive set of remote sensing, in-situ and laboratory data from our collaborators, to improve the process-level understanding of aerosol-cloud interactions. The comprehensive uncertainty analyses performed during this project will be highly valuable for future research efforts as they point to processes and interactions that most urgently need to be experimentally constrained. Furthermore, our pioneering model framework that incorporates emulators to represent subgrid- scale processes will open up completely new research opportunities also in other fields that deal with heterogeneous spatial scales.";1999511,25;1999511,25;ERC-2014-CoG;/ERC-COG;ILMATIETEEN LAITOS;FI;;;;1;0;0;1;0;0 196955;664878;2D-INK;SIGNED;H2020-EU.1.2.1.;FETOPEN-RIA-2014-2015;H2020;Redesigning 2D Materials for the Formulation of Semiconducting Inks;2016-01-01;2018-12-31;;"2D-INK is targeted at developing inks of novel 2D semiconducting materials for low-cost large-area fabrication processes on insulating substrates through a new methodology, which will exceed the properties of state-of-the-art graphene- and graphene oxide based inks. Achieving this would represent an important step forward in the processing of 2D semiconducting materials and will provide the key parameters for fabricating the next generation of ultrathin electronic appliances. The inherent high-risk of 2D-INK is countered by a strongly interdisciplinary research team composed of 9 partners (8 academics \ 1 SME) with demonstrated experience in their corresponding fields and with different yet highly complementary backgrounds. Therefore only together and in synergy they will be able to address the challenges of the multiple research and innovation aspects of 2D-INK that cover the entire value chain from materials design and synthesis, characterisation, formulation and processing to device implementation. In addition 2D-INK has the potential to revolutionise research on 2D semiconducting materials way beyond the current interests on synthesis (high impact), since the efficient dispersion and formulation of 2D semiconducting materials into inks enables the applications of 2D semiconducting materials over different scientific and technological disciplines, such as electronics, sensing, photonics, energy storage and conversion, spintronics, etc. Overall, 2D-INK addresses perfectly the challenge of this call as it is an archetype of an early stage, high risk visionary science and technology collaborative research project that explores radically new manufacturing and processing technologies for novel 2D semiconducting materials.";2962661;2962661;H2020-FETOPEN-2014-2015-RIA;/RIA;UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA;ES;"UNIVERSIDADE DO MINHO;Asociacion - Centro de Investigacion Cooperativa en Nanociencias - CIC NANOGUNE;UNIVERSITAT WIEN;GRAPHENEA SA;TECHNISCHE UNIVERSITAET MUENCHEN;UNIVERSITAT DE VALENCIA;UNIVERSIDADE DE AVEIRO;THE UNIVERSITY OF NOTTINGHAM;KATHOLIEKE UNIVERSITEIT LEUVEN";"PT;ES;AT;DE;UK;BE";;1;0;0;1;0;0 197258;647008;VOCO;SIGNED;H2020-EU.1.1.;ERC-CoG-2014;H2020;Biochemical link between plant volatile organic compound (VOC) emissions and CO2 metabolism - from sub-molecular to ecosystem scales;2015-10-01;2020-09-30;;"Plant metabolic processes exert a large influence on global climate and air quality through the emission of the greenhouse gas CO2 and volatile organic compounds (VOCs). Despite the enormous importance, processes controlling plant carbon allocation into primary and secondary metabolism, such as respiratory CO2 emission and VOC synthesis, remain unclear. This project (VOCO2) develops a novel technological and theoretical basis to couple CO2 fluxes with VOC emissions and establish a mechanistic link between primary and secondary carbon metabolism. This radically new approach uses stable isotope fractionation of central metabolites (glucose, pyruvate) to trace carbon partitioning at metabolic branching points. A unique combination of cutting-edge technology (?13CO2 laser spectroscopy, high sensitivity PTR-TOF-MS and isotope NMR spectroscopy) will allow an unprecedented assessment of carbon partitioning, bridging scales from sub-molecular to whole-plant and ecosystem processes in an interdisciplinary approach. Innovative positional 13C-labelling will break new ground quantifying real-time sub-molecular carbon investment into VOCs and CO2, enabling mechanistic descriptions of the underlying biochemical pathways coupling anabolic and catabolic processes, particularly the long overlooked link between secondary compound synthesis and CO2 emission in the light. This approach will permit the development of a novel mechanistic leaf model and its integration into a state-of-the-art ecosystem flux model. VOCO2 will set a new dimension with a world-wide first ecosystem positional labelling experiment in the unique Biosphere 2 enclosure (Arizona, US). Jointly with the novel process-based ecosystem model, VOCO2 will open new frontiers for assessing biogenic emissions of greenhouse gases at the ecosystem scale. This will deliver important information for global change related aspects, as these greenhouse gases can impact atmospheric chemistry and enhance global warming.";1895245;1895245;ERC-2014-CoG;/ERC-COG;ALBERT-LUDWIGS-UNIVERSITAET FREIBURG;DE;;;;1;0;0;1;0;0 197501;648680;DARKHORIZONS;SIGNED;H2020-EU.1.1.;ERC-CoG-2014;H2020;Dark Matter and the Early Universe in the LHC Era;2015-09-01;2020-08-31;;"The discovery of a Higgs like particle in its first science run shows that we are truly in the LHC era and when collisions resume we will learn more about the physics of the TeV scale. There are two main areas at the interface of particle physics and cosmology that the LHC will shed light on - If dark matter is a thermal relic then we naturally expect new particle physics close to this TeV energy range. The LHC will also help us learn about the nature of the electroweak sector and its behaviour during the early Universe. In this proposal we present a body of work which will combine information from the LHC with dark matter experiments and astronomical observations to understand both the nature of dark matter and the role of the Higgs sector in the first moments after the big bang. We will investigate dark matter by developing a new categorisation of interactions between the dark sector and the standard model. This will enable us to perform detailed collider and direct detection phenomenology in a more comprehensive way than current approaches while avoiding the problems which occur when those methods breakdown. Different schemes for mitigating against the upcoming problem of the neutrino floor in direct detection experiments will also be investigated. Many of the keys to understanding the particle nature of dark matter lie in astrophysics, and we will develop new techniques to understand the distribution of dark matter in the Universe, its behaviour and density in distant galaxies and its velocity dispersion in the Solar system, critical to predict event rates in detectors. We will use LHC and CMB data to answer important questions - Can the electroweak phase transition be first order? What is the role of the Higgs field during inflation? Can we use the electroweak sector to infer information about physics at high energy scale or the nature of inflation? The interdisciplinary experience of the PI will ensure the ambitious project is a success.";1947665;1947665;ERC-2014-CoG;/ERC-COG;KING'S COLLEGE LONDON;UK;;;;1;0;0;1;0;0 197223;637645;WayTO;SIGNED;H2020-EU.1.1.;ERC-StG-2014;H2020;Wayfinding Through Orientation;2015-09-01;2020-08-31;;"Wayfinding is a task that we manage every day while going to work or on vacation. Although wayfinding research has gone through tremendous development, it suffers from fundamental shortcomings: State-of-the art wayfinding research still adheres to the principles of turn-by-turn navigation. This proposal suggests a new wayfinding paradigm “Wayfinding Through Orientation” that supports the acquisition of spatial knowledge and cognitive mapping for advancing the user’s orientation. Users learn the spatial configuration of their environment through navigating. This makes wayfinding more successful because users with orientation can take informed spatial decisions. Our project goals are achieved through four objectives: 1.We develop a scientific understanding of orientation in wayfinding through empirically analyzing what kind of information induces orientation in humans. 2.We generate orientation information automatically. Orientation information is different to spatial data stored in geographic information systems, because it does not have a consistent level of generalization, it is schematized and it refers to vernacular, vague places not included in traditional maps. 3.New means of communication are developed to integrate orientation instructions into route directions. New maps are required to account for the characteristics of orientation information. 4.To evaluate orientation wayfinding, we cannot apply traditional measures such as travel time, but develop new methods to determine the effect of orientation wayfinding on peoples’ ability to solve wayfinding tasks that require orientation and cognitive mapping. “Wayfinding Through Orientation” is a paradigm change in wayfinding which has profound impact well beyond GI Science research. Our research lays the scientific foundations for a new way of navigation. We strongly believe that we have the necessary expertise to pursue this interdisciplinary project. Preliminary results have been well received by the community.";1336562,5;1336562,5;ERC-2014-STG;/ERC-STG;WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER;DE;;;;1;0;0;1;0;0 196613;642742;Enabling Excellence;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2014-ETN;H2020;Graphene-based nanomaterials for touchscreen technologies: Comprehension, Commerce and Communication;2015-04-01;2019-03-31;;"“Enabling Excellence” offers integral R&D training at PhD level around one of the most active and exciting topics at the forefront of nanoscience and nanotechnology, graphene-based nanostructures and materials. We propose a training experience built on three interrelated pillars, namely COMPREHENSION AND CONTROL, COMMERCE, and COMMUNICATION. *Comprehension & Control* covers fundamental knowledge of the nano-objects, the development of functionalities and processing into macroscopic advanced materials and devices, accompanied by a broad set of characterization techniques, to understand the interrelation between local and global properties and the requirements for functional end products. *Commerce* aims at market-ready graphene-based materials and commercial local probe Raman/AFM systems for routine quality control of graphene products. This is accompanied by innovative measures for start-up development and pitching to venture capitalists. *Communication* is the unique keystone in “Enabling Excellence”. The project is a novel experiment to find how best to develop the communication skills in our ESRs, creating optimum conditions under which they are best able to flourish. The results will serve as a model adaptable to European training and research at all levels. “Enabling Excellence” is formed by five partners from academic institutions and four private companies specialized in the above mentioned fields spanning TRL1-9. They offer a common and highly complementary modular structured training programme. During 468 ESR months we will address the need in Europe for nanocarbon specialists, training a new generation of highly skilled interdisciplinary clear thinking researchers. We will develop in these young people creativity, confidence and the ability to communicate with the most eminent scientists, technologists and business people. “Enabling Excellence” will equip them with the tools and self-belief necessary to maximize their potential in their future careers.";3358044;3358044;H2020-MSCA-ITN-2014;/MSCA-ITN-ETN;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FR;"UNIVERSIDAD DE ZARAGOZA;RENISHAW PLC;AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS;THE UNIVERSITY OF SUSSEX;ETHNIKO IDRYMA EREVNON;UNIVERSITY OF SURREY;M-SOLV LTD";"ES;UK;EL";;1;0;0;1;0;0 196966;665172;CONQUER;CLOSED;H2020-EU.1.2.1.;FETOPEN-RIA-2014-2015;H2020;Contrast by Quadrupole Enhanced Relaxation;2015-09-01;2018-08-31;;"The ageing society and demographic change is one of the major challenges which Europe is facing now, and even more so in the future. Mastering this challenge requires radically new diagnostic and therapeutic treatments as key factors in achieving the healthy well-being of European citizens. Molecular imaging (MI) plays a pivotal role in diagnosis, understanding of disease and in the development of effective treatments. CONQUER will explore a fundamentally new contrast mechanism with the potential to push magnetic resonance imaging (MRI) far beyond its limits towards a powerful MI modality. This will be achieved by exploiting the cross relaxation between 1H and large quadrupolar nuclei (QN) for contrast agent (CA) design. The main objective is to synthesize bio-compatible QN compounds and nano-particles (NPs), high efficiency and manifold degrees of freedom in the design of smart properties, such as the ability to switch the contrast on and off by changing the magnetic field or chemical binding (e.g. targeting). The NPs will be tailored based on quantum-mechanical simulations. Sensitivity and contrast switching will be demonstrated with MRI in cell cultures. This highly interdisciplinary project combines expertise in quantum physics, chemical and biomedical engineering, material characterisation as well as nanotoxicology. Today, European scientists and companies are already leading global players in CA development. CONQUER will significantly fertilise this field and lay the scientific foundations for a new technology by providing theoretical groundwork, synthesis guidelines, imaging instrumentation and toxicological references. These results will be actively transferred to academia and industry as well in order to strengthen European competitiveness. The combination of a so far unexploited quantum-mechanical phenomenon and cutting-edge imaging technologies has the potential to create MI solutions with significant impact.";2463975;2463975;H2020-FETOPEN-2014-2015-RIA;/RIA;TECHNISCHE UNIVERSITAET GRAZ;AT;"MEDIZINISCHE UNIVERSITAT GRAZ;UNIWERSYTET WARMINSKO MAZURSKI W OLSZTYNIE;UMEA UNIVERSITET;UNIVERZA V MARIBORU";"AT;PL;SE;SI";;1;0;0;1;0;0 194350;645660;TUMOCS;SIGNED;H2020-EU.1.3.3.;MSCA-RISE-2014;H2020;TUneable Multiferroics based on oxygen OCtahedral Structures;2015-01-01;2018-12-31;;The main objective of the project is development of new lead-free multiferroic materialshe for prospective application in forms of films and/or arranged layers in which the cross-coupling (magnetic-dipolar-elastic) can be tuned by both internal and external factors. This objective is to be achieved through preparation, investigation, and optimization of two kinds of Bi-containing oxygen-octahedral (BCOO) systems with paramagnetic ions involved: metastable perovskites and layered double hydroxides (LDHs). The characteristic feature of such materials is a possibility of supplementary control parameters in addition to temperature and external electric/magnetic field. Polarization in such metastable perovskites is easily switched by application of external pressure (or stress in the case of films). Electric and magnetic characteristics of BCOO LDHs are tuned through appropriate anion exchanges. It makes these characteristics dependent on environment conditions: humidity, pH, and presence of specific anion species. The BCOO materials of both mentioned groups are of interest as new and unusual multiferroics. No LDH materials have been considered as potential multiferroics so far, while the metastable BCOO materials proposed in this project have not been obtained before. Besides, a tuneability and high sensibility of their properties to external impacts make them promising for applications in sensors. Exploration and development of such materials require consolidation of specialists of complementary expertise in Physics, Chemistry, and Materials Science, with access to and skills in using specific and unique equipment and facilities. Therefore, formation of an interdisciplinary network of teams with different scientific culture and ensuring the effective knowledge & expertise transfer is important objective of the project. Advance in development of the BCOO multiferroics has potential market opportunities for R&D SME involved in this project.;814500;814500;H2020-MSCA-RISE-2014;/MSCA-RISE;UNIVERSIDADE DE AVEIRO;PT;"SMALLMATEK - SMALL MATERIALS AND TECHNOLOGIES LDA;UNIVERSITAET DUISBURG-ESSEN;HELMHOLTZ-ZENTRUM GEESTHACHT ZENTRUM FUR MATERIAL- UND KUSTENFORSCHUNG GMBH;SCIENCE AND TECHNOLOGY FACILITIES COUNCIL;VILNIAUS UNIVERSITETAS;UNITED KINGDOM RESEARCH AND INNOVATION";"PT;DE;UK;LT";;1;0;0;1;0;0 194132;644015;Geopark;SIGNED;H2020-EU.1.3.3.;MSCA-RISE-2014;H2020;Geoparks: Heritage, Education and Sustainable Development - an Innovative Methodology for Southern Countries. Case Study in Morocco (Atlas Mountains, Marrakech);2015-01-01;2018-12-31;;According to the Charter of the European Geoparks Network adopted in Greece the 5th June of 2000, a European Geopark “is a territory which includes a particular geological heritage and a sustainable territorial development strategy supported by a European programme to promote development. […]”.These territories have been labelled regarding their geological, cultural and ecological heritage - since the early 2000s this Label knows a growing success among European countries, particularly in the West (France, Germany, Italy, Spain). In 2013, 54 European Geoparks received the precious label. This international recognition by UNESCO attracts Southern countries to implement development strategies in line with the recommendations of good-practices management oriented by international organizations. Indeed, UNESCO takes into account a plurality of selective criteria such as a remarkable heritage (geology, archaeology, biodiversity, cultural), citizen participation, sustainable regional economic development plan, heritage and socio-economic values for local populations, etc. to proceed to the inscription process. It is based on an integrated and sustainable management & conservation strategy of natural and cultural heritage from an interdisciplinary approach (Humanities and Life & Earth Sciences) in consultation with local stakeholders (local communities, universities and civil society). Currently, there is no “Geopark methodology” adapted to the South. Thus, the GEOPARK project aims to study potential and compared areas (EU/Africa) with remarkable geological, ecological, social and cultural heritage. One located in Central Catalunia (Spain) and the other in the Zat Valley (Morocco) - Marrakech. Endowed with varied skills in Humanities and Life and Earth Sciences, GEOPARK project partners (public, private) propose to study biodiversity, geology, prehistory, social aspects, heritage, tourism as a geopark based on empirical surveys, field collecting data and shared experience.;1296000;1296000;H2020-MSCA-RISE-2014;/MSCA-RISE;MUSEUM NATIONAL D'HISTOIRE NATURELLE;FR;"CABILDO INSULAR DE LANZAROTE;UNIVERSITE PARIS DIDEROT - PARIS 7;ASSOCIACIO GEOPARC CONCA DE TREMP -MONTSEC;MARTIN LOYER;UNIVERSITE PARIS III SORBONNE NOUVELLE;CERDAN INGENIEROS S.L.;UNIVERSITE D'AVIGNON ET DES PAYS DE VAUCLUSE;UNIVERSITE D'AIX MARSEILLE;UNIVERSITAT AUTONOMA DE BARCELONA";"ES;FR";;1;0;0;1;0;0 195003;654837;EACISD;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2014-GF;H2020;Embodied and Abstract Concepts in Sensory-motor Deprivation;2015-05-01;2019-04-30;;"How is information organized in the brain? Does our understanding of everyday concepts rely on our perceptual experience, and our ability to sense them? And can this uncover how abstract information is coded in our brains? These puzzles are at core of cognitive neuroscience and brain organization. Two major theoretical bodies differ in their account of neural concept organization: Classical cognitive theories propose that concepts are symbolic and non-sensory, and are further linked to sensory-motor aspects, whereas embodied cognition theories (e.g. mirror neuron system theory) postulate that concepts are represented only in a sensory-motor manner, and representations depend on the ability to simulate, re-enact, its perceptual process or action. To address this contradictory account of concepts organization, a systematic interdisciplinary neuroimaging investigation will be conducted in a combination of special populations, each deprived from birth from an entire sensory modality or ability. The neural correlates of impossible-to-embody concepts will be studied in congenitally blind (e.g. rainbow), deaf (e.g. jazz) and ULD subjects (born without functional hands; e.g. manually handles tools). Brain responses will be analyzed using multiple, state-of-the-art neuroimaging decoding techniques to reveal brain areas representation content and dependence on sensory experience. The neural networks of such concepts will be charted, to investigate the link between abstract thought and sensory inputs. A novel non-linear measurement method to quantity the richness of representations will be developed and applied to the sensorily-deprived groups, to map the dimensions related to specific sensory modalities. At the final stage, these methods will also be applied to study the developing brain in children. The findings have the potential to revolutionize our understanding of brain organization and pave the road towards rehabilitation of multiple sensory and cognitive deficits.";263385;263385;H2020-MSCA-IF-2014;/MSCA-IF-GF;BEN-GURION UNIVERSITY OF THE NEGEV;IL;;;;1;0;0;1;0;0 195467;657539;STARMAS;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Structured Training and Advanced Research in Marine Active Structures;2016-05-01;2018-04-30;;In the last 25 years the total amount of marine trade has nearly doubled. In the same period the container trade has undergone a tenfold increase, making the container fleet the fastest growing fleet at present. With 80% of total EU trade being transported by sea, the maritime transport is of the greatest importance to the EU. The increasing demand in container transportation is met by use of more containerships. Such ships with large bow and stern flares and fine underwater hull are severely hit by an effect known as parametric rolling. Accidents including container loss and vessel structural damage are reported from all around the world. Capsizing could be regarded as a rare event, but the consequences of such event are fatal (loss of the ship and the crew). Agencies, classification societies and the public are showing more and more interests in increasing the safety of large container ships. STARMAS is a highly interdisciplinary integrated research and training programme focused on the application of novel active control methods to increase safety, energy efficiency and quality of life at sea of the 21st century maritime transport. The problem of ship roll on rough seas will be tackled using novel active roll control methodologies. Bi-directional transfer of knowledge and cross-fertilisation between traditionally detached engineering disciplines will be unlocked, utilising a unique research approach to enduring engineering problems related to sea keeping, survival rate, and energy efficiency of marine vessels. The programme will boost the career prospects, increase employability and widen the set of skills of the experienced researcher. The training and research will predominately take place within the academic sector, at the Faculty of Mechanical Engineering and Naval Architecture (FAMENA). The researcher will also benefit from secondments to the non-academic partner Bureau Veritas, Paris, (BV) facilitating an inter-sectoral transfer of knowledge.;158010;158010;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;SVEUCILISTE U ZAGREBU, FAKULTET STROJARSTVA I BRODOGRADNJE;HR;;;;1;0;0;1;0;0 193874;642014;IPCOS;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2014-EID;H2020;Imprinted Polymers as Coffee Sensors;2015-01-01;2018-12-31;;Food quality is a global key priority area where technological advances in terms of quality control have been limited. The aim of the IPCOS Network is to bring innovation to the field of food quality by offering an international, interdisciplinary and intersectorial doctoral training programme that will target the development of chemical sensors, using the molecular imprinting technology, for application in the coffee industry, focusing on three main targets: chlorogenic acids, cafestol and kaurene terpenes, caffeine and its metabolites, all of which have been shown to have an impact on consumers’ health. This project brings together 2 academic teams, 1 large international company, 1 SME and one non-profit research centre of excellent, supported by 4 associated teams, with a very multidisciplinary and multisectorial expertise. The IPCOS training program will require ESRs to work 50% of their time in industry, providing them with a set of unique scientific and transferable skills that will match both public and private sector needs, together with a strong development of innovation and entrepreneurship ethos, therefore considerably enhancing their career perspectives. All researchers will aim to achieve a doctoral degree at the end of their training. As a result of the close collaborative links, IPCOS will strengthen the innovation capacity of universities/research institutes to commercially exploit their research and enhance the research potential and competitiveness of European companies and SMEs.;1335986,28;1335986,28;H2020-MSCA-ITN-2014;/MSCA-ITN-EID;QUEEN MARY UNIVERSITY OF LONDON;UK;"UNIVERSITA DEGLI STUDI DI TRIESTE;BIOREALIS SRO;ILLYCAFFE S.P.A;CENTER ODLICNOSTI ZA BIOSENZORIKO,INSTRUMENTACIJO IN PROCESNO KONTROLO ZAVOD";"IT;SK;SI";;1;0;0;1;0;0 193926;642574;SPRInG;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2014-EID;H2020;Short Period Superlattices for Rational (In,Ga)N;2015-01-01;2018-12-31;;"The scientific mission of this project is to develop a novel (In,Ga)N alloy that offers completely new opportunities to tune bandgaps and piezoelectric fields in quantum structures for highly efficient optoelectronic devices. This novel “rational” (n InN/m GaN) alloy is based on short period superlattices that stack integer numbers of m (n) monolayers (MLs) of InN (GaN), i.e. heterostructures of pure InN MLs embedded in a GaN matrix. The development of fundamental knowledge on this rational (InN/GaN) alloy as established for other III-V compounds is envisioned as the base for such devices. This objective will be achieved by a bilateral collaboration and the concerted action between Forschungsverbund Berlin (FVB) as academic institution, and TopGaN sp.z.o.o. (TopGaN) as non-academic partner. Besides, the Humboldt-Universität zu Berlin (HU) and the Institute of High- Pressure Physics – Polish Academy of Sciences (UNIPRESS) will also be involved as external partner organizations. As a specific strength, within the project “Short Period Superlattices for Rational (In,Ga)N” (SPRInG) we aim at unifying a unique portfolio of experimental competencies with high-level resources and infrastructures. These create an ideal research environment designed to promote an interdisciplinary collaboration and an international networking of the early-stage researchers (ESRs). The students will professionally develop and meet the challenge to solve very exciting scientific questions of the potential III-nitride future technology for solid state lighting. A quality monitoring scheme will ensure that the ESRs will receive an optimised training, which will prepare and qualify them for the research and development of future technologies in academic and non-academic organizations.";1221003,36;1221003,36;H2020-MSCA-ITN-2014;/MSCA-ITN-EID;FORSCHUNGSVERBUND BERLIN EV;DE;TOP-GAN SP ZOO;PL;;1;0;0;1;0;0 193660;639564;HERITAGE;SIGNED;H2020-EU.1.1.;ERC-StG-2014;H2020;Cultural Heritage and Economic Development in International and European Law;2015-05-01;2018-08-31;;"Can states promote economic development without infringing upon their cultural heritage? Although economic globalization and international economic governance have spurred a more intense dialogue and interaction among nations - potentially promoting cultural diversity and providing the funds to recover and preserve cultural heritage - these phenomena can also jeopardize the cultural wealth of nations. Trade in cultural products can lead to cultural homogenization and even to cultural hegemony. In parallel, foreign direct investments have an unmatched penetrating force with the ultimate capacity of changing landscapes and erasing memory. At the same time, the increase in global trade, economic integration and foreign direct investment has determined the creation of legally binding and highly effective regimes that demand states to promote and facilitate trade and foreign direct investment. Has an international economic culture emerged that emphasizes productivity and economic development at the expense of cultural wealth? Does the existing legal framework adequately protect the cultural wealth of nations vis-?-vis economic globalization? Could existing mechanisms in international and European law constrain negative effects of globalization? HERITAGE aims to map the interaction between economic globalization and each specimen of cultural heritage - world heritage, cultural diversity, intangible cultural heritage, indigenous heritage and underwater cultural heritage - in international and European law by investigating the relevant case law before international courts and tribunals. The study adopts an interdisciplinary approach; the relevant cases will be investigated in consideration of both their legal and cultural relevance. The main outcome of this research project will be a monograph written by the principal investigator to be published by a major international publisher; and a number of articles to be published in major international journals.";485137,5;485137,5;ERC-2014-STG;/ERC-STG;LANCASTER UNIVERSITY;UK;;;;1;0;0;1;0;0 193586;638605;SenseX;SIGNED;H2020-EU.1.1.;ERC-StG-2014;H2020;Sensory Experiences for Interactive Technologies;2015-04-01;2020-03-31;;"The senses we call upon to interact with technology are still very limited relying mostly on visual and auditory senses. The grand challenge and vision of this project is to gain a rich and integrated understanding on touch, taste, and smell experiences for interactive technologies. We aim to achieve this ambitious grand vision by 1) creating a ‘sensory interaction framework’ on the bases of a systematic empirical investigation of touch, taste, and smell experiences, 2) integrating the generated understanding on the three senses into meaningful and efficient experiential cross-sensory gamuts and interaction principles, and 3) demonstrating the added value of the created experiential understanding on touch, taste, and smell – aka the experiential gamuts – through their integration into the development of multi-sensory systems verifying the short-, mid- and long-term societal and scientific impact (short-term: multi-sensory media experiences; mid-term: interaction concepts for partially sensory impaired people; long-term: multi-sensory interaction approach for life beyond Earth). This research will pioneer novel interaction concepts for interactive technologies in relation to essential components of multi-sensory experiences. This project will transform existing interaction paradigm in Human-Computer Interaction (HCI) and likewise impact other disciplines such as sensory and cognitive sciences by delivering ground-breaking new insights on the experiential dimensions underlying neurological processes and human perception. The PI’s research excellence and her track record (three recent seminal papers on touch, taste, and smell at the premier HCI – CHI conference) provide a rock solid foundation for the feasibility of the proposed scientific venture. This ERC project would enable her to establish an independent and interdisciplinary team to revolutionize multi-sensory research within the HCI community with impact across disciplines.";1494865;1494865;ERC-2014-STG;/ERC-STG;THE UNIVERSITY OF SUSSEX;UK;;;;1;0;0;1;0;0 194068;643476;COMPARE;SIGNED;H2020-EU.3.1.2.;PHC-07-2014;H2020;COllaborative Management Platform for detection and Analyses of (Re-)emerging and foodborne outbreaks in Europe;2014-12-01;2019-11-30;;"COMPARE aims to harness the rapid advances in molecular technology to improve identification and mitigation of emerging infectious diseases and foodborne outbreaks. To this purpose COMPARE will establish a “One serves all” analytical framework and data exchange platform that will allow real time analysis and interpretation of sequence-based pathogen data in combination with associated data (e.g. clinical, epidemiological data) in an integrated inter-sectorial, interdisciplinary, international, “one health” approach. The framework will link research, clinical and public health organisations active in human health, animal health, and food safety in Europe and beyond, to develop (i) integrated risk assessment and risk based collection of samples and data, (ii) harmonised workflows for generating comparable sequence and associated data, (iii) state-of-the-art analytical workflows and tools for generating actionable information for support of patient diagnosis, treatment, outbreak detection and -investigation and (iv) risk communication tools. The analytical workflows will be linked to a flexible, scalable and open-source data- and information platform supporting rapid sharing, interrogation and analysis of sequence-based pathogen data in combination with other associated data. The system will be linked to existing and future complementary systems, networks and databases such as those used by ECDC, NCBI and EFSA. The functionalities of the system will be tested and fine tuned through underpinning research studies on priority pathogens covering healthcare-associated infections, food-borne disease, and (zoonotic) (re-) emerging diseases with epidemic or pandemic potential. Throughout the project, extensive consultations with future users, studies into the barriers to open data sharing, dissemination and training activities and studies on the cost-effectiveness of the system will support future sustainable user uptake.";20847771;20817771;H2020-PHC-2014-single-stage;/RIA;DANMARKS TEKNISKE UNIVERSITET;DK;"UNIVERSITEIT ANTWERPEN;THE SECRETARY OF STATE FOR ENVIRONMENT, FOOD AND RURAL AFFAIRS;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;STIFTUNG TIERAERZTLICHE HOCHSCHULE HANNOVER;ROBERT KOCH-INSTITUT;FRIEDRICH LOEFFLER INSTITUT - BUNDESFORSCHUNGSINSTITUT FUER TIERGESUNDHEIT;STATENS SERUM INSTITUT;GENOME RESEARCH LIMITED;EUROPEAN MOLECULAR BIOLOGY LABORATORY;UNIVERSITAETSKLINIKUM BONN;ARISTOTELIO PANEPISTIMIO THESSALONIKIS;RESPONSIBLE TECHNOLOGY;ISTITUTO SUPERIORE DI SANITA;ARTEMIS ONE HEALTH RESEARCH BV;CIVIC CONSULTING GMBH;FONDATION MERIEUX;RIJKSINSTITUUT VOOR VOLKSGEZONDHEID EN MILIEU;CIVIC CONSULTING ALLEWELDT & KARA GBR;CHARITE - UNIVERSITAETSMEDIZIN BERLIN;MAGYAR TUDOMANYOS AKADEMIA WIGNER FIZIKAI KUTATOKOZPONT;LEIBNIZ-INSTITUT DSMZ-DEUTSCHE SAMMLUNG VON MIKROORGANISMEN UND ZELLKULTUREN GMBH*;INSTITUT FRANCAIS DE RECHERCHE POUR L'EXPLOITATION DE LA MER;UNIVERSIDAD DE CASTILLA - LA MANCHA;ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA;ERASMUS UNIVERSITEIT ROTTERDAM;ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM;THE AUSTRALIAN NATIONAL UNIVERSITY;Academisch Medisch Centrum bij de Universiteit van Amsterdam;AGENCE NATIONALE DE LA SECURITE SANITAIRE DE L ALIMENTATION DE L ENVIRONNEMENT ET DU TRAVAIL;THE UNIVERSITY OF EDINBURGH";"BE;UK;DE;DK;EL;FR;IT;NL;HU;ES;AU";;1;0;0;1;0;0 195314;656738;INHABIT Cities;CLOSED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Investigating Natural, Historical, And Institutional Transformations - Cities;2015-09-14;2018-08-14;;"The overall aim of INHAbIT is to improve understandings of the dynamics of water service provision in urban environments in the global South. In particular, INHAbIT will explore historical processes and transformations that have shaped water service configurations, the politics of socio-technical urban water supply systems and the socio-ecological processes shaping the urban waterscape. INHAbIT is innovative in that it takes an interdisciplinary approach and aims at developing new methodologies and conceptual approaches. To this aim, INHAbIT has identified three objectives, which combine theoretical, methodological and empirical elements: undertake a theoretical synthesis that brings urban political ecology perspectives into engagement with institutional bricolage; explore and test innovative methodologies for tracking informality and investigating socio-natural processes; undertake empirical work and building up a robust body of rigorously researched historical and qualitative data on natural, historical and institutional transformations that have shaped and continuously re-shape water service realities in Lilongwe (Malawi) and Maputo (Mozambique). While taking a critical approach, INHAbIT is also cognizant of the needs of policy makers and practitioners for solutions that work for serving with adequate water a growing population. The researcher, Maria Rusca, will explore the implications of INHAbIT’s research findings for policy and practice and disseminate accordingly. INHAbIT, thus, will be both scientifically innovative and policy relevant.";183454,8;183454,8;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;KING'S COLLEGE LONDON;UK;;;;1;0;0;1;0;0 195350;656886;SmartMammaCAD;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2014-GF;H2020;Intelligent Automated System for detecting Diagnostically Challenging Breast Cancers;2015-09-01;2018-08-31;;"In this project, Dr. Ignacio Alvarez Illan proposes to develop a novel automated diagnosis system that supports the radiologist in the breast cancer diagnosis in Dynamic Contrast Enhance-Magnetic Resonance Imaging (DCE-MRI) by including critical components of the radiological work-flow such as motion compensation, segmentation and diagnosis of breast tumours. The expected results of this interdisciplinary project will definitely have applications and impact in the European society and its health and the overarching goals of the '2020 Vision for the European Research Area’. Specifically, improving diagnosis of major diseases such as breast cancer is a research priority in the European Union. The main goal and overall objective of this project is to develop computer aided diagnosis (CAD) methods, and image processing techniques to improve diagnostic accuracy and efficiency of cancerrelated breast lesions. Non-mass-enhancing lesions exhibit a heterogeneous appearance in breast MRI with high variations in kinetic characteristics and typical morphological parameters, and have a specificity and sensitivity much lower than mass-enhancing lesions. For this reason, new segmentation algorithms and kinetic parameters can be potentially used as an alternative to the methods for mass-enhanced lesions. To develop and implement CAD methods and image processing techniques, three different research objectives are presented in this project. They include basic research, strategic research, applied research and transfer of knowledge: i) Develop non-rigid registration and segmentation techniques to incorporate spatial variations in temporal enhancement. ii) Develop kinetic feature descriptors to quantify significant differences between the benign and malignant lesions. iii) Develop and validate algorithms, interfaces and software implementation for real applications of CAD of breast cancer.";257191,2;257191,2;H2020-MSCA-IF-2014;/MSCA-IF-GF;UNIVERSIDAD DE GRANADA;ES;;;;1;0;0;1;0;0 193900;642295;MEL-PLEX;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2014-ETN;H2020;Exploiting MELanoma disease comPLEXity to address European research training needs in translational cancer systems biology and cancer systems medicine;2014-12-01;2018-11-30;;Novel treatment options and associated personalised, patient-tailored therapies need to be explored and developed for highly heterogeneous and chemotherapy resistant cancers, such as malignant melanoma. This can only be achieved by industry-academia collaborations in newly emerging, innovative research disciplines such as translational cancer systems biology and systems medicine. These disciplines and the associated European training needs provide the foundation for the MEL-PLEX ETN. MEL-PLEX aims to understand the network-level and multi-scale regulation of disease-relevant signalling in melanoma through a combination of quantitative biomedical and computational research approaches that go significantly beyond the current state-of-the-art. Coordinated by the RCSI Centre for Systems Medicine, MEL-PLEX will train 15 early stage researchers through a highly interdisciplinary and intersectoral research training programme. MEL-PLEX comprises 11 beneficiaries and 7 partner organisations from 11 countries, including European and international leaders in personalised melanoma therapy, melanoma systems biology and cancer systems medicine. MEL-PLEX aims to (i) achieve an unmatched depth of molecular and mechanistic disease understanding, (ii) will exploit this knowledge to develop and validate predictive models for disease progression, prognosis and responsiveness to current and novel (co-)treatment options, and (iii) will provide superior and clinically relevant tools and biomarker signatures for personalising and optimising melanoma treatment. The MEL-PLEX ETN addresses current needs in academia and the private sector for researchers that have been trained in an environment that spans across biology, medicine and mathematics, that can navigate confidently between clinical, academic and private sector research environments, and that have developed an innovative and creative mindset to progress research findings towards applications.;3583870,17;3583870,17;H2020-MSCA-ITN-2014;/MSCA-ITN-ETN;ROYAL COLLEGE OF SURGEONS IN IRELAND;IE;"UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN;UNIVERSITAETSKLINIKUM AACHEN;ONCOMARK LIMITED;RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG;UNIVERSITE DU LUXEMBOURG;PROTATOUANS - ETAIREIA EREYNAS VIOTECHNOLOGIAS MONOPROSOPI ETAIREIA PERIORISMENIS EYTHINIS;OPTIMATA LTD;UNIVERSITAET STUTTGART;KATHOLIEKE UNIVERSITEIT LEUVEN;KRAEFTENS BEKAEMPELSE;TECHNISCHE UNIVERSITAET DRESDEN";"IE;DE;LU;EL;IL;BE;DK";;1;0;0;1;0;0 193860;641887;DEFNET;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2014-ETN;H2020;DEFect NETwork materials science and engineering;2015-01-01;2018-12-31;;Porous coordination network materials, also known as Metal-organic Frameworks (MOFs), are at the cutting edge of molecular materials science. DEFNET, “DEFect NETwork materials science and engineering”, is the first European Training Network (ETN) at the intersection of chemistry, physics and engineering aimed at structural and functional complexity of MOFs. It provides a unique interdisciplinary training platform for early stage researchers and combines the expertise of the academic and the non-academic sector for fundamental development and industrial application and technology transfer aspects. The research and the training program in materials synthesis, characterization, computational modelling and application is accomplished in a coordinated effort involving 8 academic and 8 industrial partners from 6 European countries. DEFNET will particularly investigate defects, disorder and correlated phenomena in MOFs and related materials. The understanding and the intentional modification of defect structures of porous coordination networks is essential for advanced controlling their properties in catalysis, gas capture and separation beyond existing materials limitations. Benchmarking will be done against selected zeolite materials, which are very well established for large scale industrial applications. It is anticipated that superior functionalities of defect engineered MOFs will be identified which cannot be achieved by employing other porous materials.;3804639,48;3804639,48;H2020-MSCA-ITN-2014;/MSCA-ITN-ETN;RUHR-UNIVERSITAET BOCHUM;DE;"RUBOTHERM GMBH;UNIVERSITEIT GENT;TECHNISCHE UNIVERSITAET MUENCHEN;AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS;SOFTWARE FOR CHEMISTRY & MATERIALS BV;TECHNISCHE UNIVERSITAET BERGAKADEMIE FREIBERG;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;UNIVERSITEIT UTRECHT;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;KATHOLIEKE UNIVERSITEIT LEUVEN";"DE;BE;ES;NL;UK;FR";;1;0;0;1;0;0 193972;642973;PRIDE;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2014-ETN;H2020;Drivers of Pontocaspian biodiversity RIse and DEmise;2015-03-01;2019-02-28;;Since the 1930s, the unique endemic aquatic biota of the Caspian-Black Sea region is facing a biodiversity crisis as it is severely affected by anthropogenic activities such as habitat destruction, invasive species and pollution. Understanding long-term natural biotic and abiotic drivers of lake system change and biotic response to perturbations in the past 2 Ma – i.e. gradual, rapid and/or threshold responses – is absolutely necessary to assess the current response of Pontocaspian biota to rising natural- and human-induced perturbations. The Pontocaspian example mirrors the complex global ecological and biodiversity challenge due to Global Change. This challenge can only be addressed through an integrated cross-disciplinary research involving climate, earth- and bio-sciences. PRIDE (Pontocaspian biodiversity RIse and DEmise) is a fully integrated academia-industry training network of scientists with complementary cutting-edge competences. PRIDE focuses on the evolution of Pontocaspian biota over the past 2 million years. The extraordinary endemic biodiversity, coupled with a high-amplitude record of palaeoenvironmental change, makes it an ideal system to study drivers of past and current biodiversity crises. By linking Pontocaspian palaeoenvironmental and biodiversity changes we will reconstruct biological resilience to environmental change and apply this knowledge to the current Pontocaspian biodiversity crisis to model future diversity shifts under different Global Change scenarios. PRIDE will provide outstanding interdisciplinary technical training, new skills acquisition and career development for 15 early stage researchers. An innovative outreach plan will deliver our results to stakeholders and the public. PRIDE results from existing, successful collaborative relationships and will expand to include 17 first-class private and academic geological and biological institutions allowing Europe to remain world-leading in integrated studies of biodiversity change.;3784088,6;3784088,6;H2020-MSCA-ITN-2014;/MSCA-ITN-ETN;STICHTING NATURALIS BIODIVERSITY CENTER;NL;"UNIVERSITATEA DIN BUCURESTI;THE UNIVERSITY OF READING;MUZEUL NATIONAL DE ISTORIE NATURALA GRIGORE ANTIPA;GIMARIS;JUSTUS-LIEBIG-UNIVERSITAET GIESSEN;UNIVERSITAET BREMEN;UNIVERSITY OF BRISTOL;BRUNEL UNIVERSITY LONDON;UNIVERSITEIT UTRECHT";"RO;UK;NL;DE";;1;0;0;1;0;0 193898;642242;CARISMA;SIGNED;H2020-EU.3.5.1.;SC5-05a-2014;H2020;Coordination and Assessment of Research and Innovation in Support of Climate Mitigation Actions;2015-02-01;2018-07-31;;"The CARISMA project has two overall objectives. First, through effective stakeholder consultation and communication leading to improved coordination and assessment of climate change mitigation options, it aims to benefit research and innovation efficiency as well as international cooperation on research and innovation and technology transfer. Second, it seeks to assess policy and governance questions that shape the prospects of climate change mitigation options, and discuss the results with representatives from the CARISMA target audiences to incorporate what can be learned for the benefit of climate change mitigation. The experienced, interdisciplinary and diverse CARISMA consortium has an extensive track record of collaborating in Framework Programme projects. It combines capacity for technological, environmental, economic and social assessment with deep expertise across a range of climate change mitigation options, encompassing mature and emerging technologies as well as practices and governance, which are increasingly identified as important areas to achieve deep greenhouse gas emission reductions. Communication with, and support to, the CARISMA target audiences are an integral part of the project. In all inventory and assessment activities envisaged in the project, interaction with stakeholders is a key part. To facilitate coordination and avoid overlap, these activities are overseen by a dedicated work package. The target audiences include national and local policymakers, innovation and strategy managers in business and industry, research funding organisations and the research community. The CARISMA project will result in online platform services, face-to-face interactions, policy briefs and publications and increased capacity in the EU, Accession Countries and beyond, to address the climate change challenge and move towards a green, innovative and thriving global economy.";2066653,75;2064403,75;H2020-SC5-2014-one-stage;/CSA;STICHTING KATHOLIEKE UNIVERSITEIT;NL;"CDC CLIMAT;I4CE - INSTITUTE FOR CLIMATE ECONOMICS;CENTRE FOR EUROPEAN POLICY STUDIES;STICHTING JOINT IMPLEMENTATION NETWORK;STIFTELSEN THE STOCKHOLM ENVIRONMENT INSTITUTE;ZEW - LEIBNIZ-ZENTRUM FUR EUROPAISCHE WIRTSCHAFTSFORSCHUNG GMBH MANNHEIM;ENVIROS SRO;UNIVERSITY OF PIRAEUS RESEARCH CENTER;DANMARKS TEKNISKE UNIVERSITET;UNIVERSITAET GRAZ";"FR;BE;NL;SE;DE;CZ;EL;DK;AT";;1;0;0;1;0;0 193856;641839;DiStruc;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2014-ETN;H2020;Directed Colloidal Structure at the Meso-Scale;2015-01-01;2018-12-31;;"Fluid dispersions containing highly elongated colloidal particles form a plethora of ordered, liquid-crystalline states as well as glassy and gel-like disordered states already at very low concentrations. In spite of their remarkable properties, industrial applications of such dispersions have entered the market only relatively recently, in contrast to more conventional low-molecular-weight, liquid-crystalline fluids for which the major practical applications are in opto-electronic device technology, e.g., in displays, optical imaging and smart glass. Important potential applications of colloidal liquid crystals can be found in the manufacturing of high-performance fibres and in fast moving consumer goods, such as foods and home and personal care. To accelerate their exploitation and market introduction, we seek to push the field in a new, innovative direction where rod-like colloidal particles of a very diverse nature are used to form structures with a well-defined direction: Directed Structure (DiStruc) at the mesoscopic level. Our focus will be on the role of confinement and flow, highly relevant to industrial applications. This will open avenues for a bottom-up, rational design of industrial processes, which is an important step to protect the competitive role of European industries on the global market. At the same time, scientifically novel physical phenomena will be explored protecting the leading role of Europe in the field of soft condensed matter. Importantly, it provides a training ground for the next generation of European researchers, unique in its interdisciplinary scope, covering physics, chemistry, biology, materials and engineering, its depth, creating a mind-set where experiments, theory and computer simulations go hand-in-hand, and its focus on the chain of knowledge from basic to applied research through close industrial involvement.";3613194,36;3613194,36;H2020-MSCA-ITN-2014;/MSCA-ITN-ETN;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;UK;"FORSCHUNGSZENTRUM JULICH GMBH;UNILEVER RESEARCH AND DEVELOPMENT VLAARDINGEN BV;FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS;TECHNISCHE UNIVERSITEIT EINDHOVEN;ASSOCIATION POUR LE DEVELOPPEMENT DE L'ENSEIGNEMENT ET DES RECHERCHES AUPRES DES UNIVERSITES, DES CENTRES DE RECHERCHE ET DES ENTREPRISES D'AQUITAINE;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;TEIJIN ARAMID BV";"DE;NL;EL;FR";;1;0;0;1;0;0 193938;642682;AWESCO;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2014-ETN;H2020;Airborne Wind Energy System Modelling, Control and Optimisation;2015-01-01;2018-12-31;;"The height of conventional wind turbines is limited by the enormous stresses on the structure. The idea of the Airborne Wind Energy (AWE) is to replace the most efficient part of a conventional wind turbine, the tip of the turbine blade, with a fast flying high efficiency kite, and to replace the rest of the structure by a tether which anchors the kite to the ground. Power is generated either by periodically pulling a ground based generator via a winch, or by small wind turbines mounted on the kite that exploit its fast cross wind motion. While the concept is highly promising, major academic and industrial research is still needed to achieve the performance required for industrial deployment. This can best be done by innovative junior researchers in a closely cooperating consortium of academic and industrial partners. The ITN AWESCO combines six interdisciplinary academic and four industrial network partners with seven associated partners, all selected on the basis of excellence and complementarity. All partners work already intensively on AWE systems, several with prototypes, and they are committed to create synergies via the cooperation in AWESCO. The main task is to train fourteen Early Stage Researchers (ESRs) in training-by-research and to create a closely connected new generation of leading European scientists that are ready to push the frontiers of airborne wind energy. AWESCO is the first major cooperation effort of the most important European actors in the field and will help Europe to gain a leading role in a possibly huge emerging renewable energy market, and to meet its ambitious CO2 targets. In addition, the AWESCO early stage researchers will be trained in cutting-edge simulation, design, sensing, and control technologies that are needed in many branches of engineering.";2990467,2;2990467,2;H2020-MSCA-ITN-2014;/MSCA-ITN-ETN;TECHNISCHE UNIVERSITEIT DELFT;NL;"XSENS TECHNOLOGIES B.V.;TECHNISCHE UNIVERSITAET MUENCHEN;SKYSAILS GMBH;ALBERT-LUDWIGS-UNIVERSITAET FREIBURG;AMPYX POWER BV;UNIVERSITY OF LIMERICK;HOCHSCHULE FUR ANGEWANDTE WISSENSCHAFTEN MUNCHEN;KATHOLIEKE UNIVERSITEIT LEUVEN;ENERKITE GMBH;CHALMERS TEKNISKA HOEGSKOLA AB";"NL;DE;IE;BE;SE";;1;0;0;1;0;0 193906;642355;FIWIN5G;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2014-ETN;H2020;FIber-Wireless Integrated Networks for 5th Generation delivery.;2015-01-01;2018-12-31;;"This European Training Network aims to produce the next generation of early stage researchers who will enable Europe to take a leading role in the development of future devices, systems and networks supporting the 5G high-speed wireless internet. To do this, researchers must be able to work in interdisciplinary teams, integrate their activities, share expertise, and promote a vision of a converged wireless and optical devices and networks that efficiently supports the services and applications being demanded. A large number of technologies and devices will need to converge, co-exist and interoperate, and most importantly, cooperate, if this vision is to be efficiently and cost-effectively realised. A key area within this next generation jigsaw is the integration of optical fibre networks and radio networks at mm-wave frequencies, to provide high-bandwidth front/backhaul services and enable scalable and manageable networks without a highly complex interface structure and multiple overlaid protocols. FIWIN5G aims to provide doctoral students with the exposure to the range of skills, necessary to address these challenging demands. Deep technical knowledge but also key transferable skills common in entrepreneurship, management, financing as well as communication, and societal outreach. While becoming expects in one particular sub-domain, they must understand the broad context of their work, whether it is systems/network engineers understanding the devices and technologies that make up the networks or device engineers understanding the networks in which their devices will function. We draw together a range of world-leading partners, selected for their complimentary and excellence to offer a vital opportunity to advance industry’s understanding and uptake of the key technologies in this area. To provide excellent training and diverse experience of research environments, all project involve a significant period of secondment and collaboration with an industry partner.";3867896,88;3867896,88;H2020-MSCA-ITN-2014;/MSCA-ITN-ETN;UNIVERSITY COLLEGE LONDON;UK;"INSTITUT POLYTECHNIQUE DE GRENOBLE;BUDAPESTI MUSZAKI ES GAZDASAGTUDOMANYI EGYETEM;UNIVERSITAET DUISBURG-ESSEN;DANMARKS TEKNISKE UNIVERSITET;III-V LAB;UNIVERSITY OF CYPRUS;CONSORZIO NAZIONALE INTERUNIVERSITARIO PER LE TELECOMUNICAZIONI;UNIVERSIDAD CARLOS III DE MADRID;UNIVERZA V LJUBLJANI";"FR;HU;DE;DK;CY;IT;ES;SI";;1;0;0;1;0;0 193996;643161;ECRYPT-NET;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2014-ETN;H2020;European Integrated Research Training Network on Advanced Cryptographic Technologies for the Internet of Things and the Cloud;2015-03-01;2019-02-28;;"The goal of this ETN is to develop advanced cryptographic techniques for the Internet of Things and the Cloud and to create implementations that offer a high level of security and increased usability, for a wide range of physical computation platforms. The ITN will equip a group of 15 early stage researchers with a set of interdisciplinary skills combining mathematics, computer science and electrical engineering that will allow them to create advanced cryptographic solutions that will be available for commercial applications. The 8 partners (including 2 companies) are leading research teams in the area of applied cryptology with a strong track record of collaboration; it is complemented by 6 partner organisations from industry (including 2 SMEs).The training from the ERSs will be guided by a personal development plan. A central component is training by research supported by an intensive program of workshops, summer schools, seminars, research visits, and secondments. The training will be complemented with transferable skills that also support the transfer of research to an industrial context. The management structure of the project is built on a pro-active approach with responsibilization of the fellows. The dissemination and outreach of the project activities target a broad range of stakeholders. The ITN contributes to the ERA by helping to overcome the fragmentation in the area of applied cryptology. The research supports the trust and security component of the Digital Agenda for Europe and responds to the growing attention of EU policy makers for societal needs related to privacy and cybersecurity. The societal relevance and timeliness of this research has been emphasized by revelations made by Snowden, that provide clear evidence of mass surveillance by nation states and of serious weaknesses of our current infrastructure. An essential component of a response to these revelations consists a broad deployment of advanced and innovative cryptographic techniques.";3893199,84;3893199,84;H2020-MSCA-ITN-2014;/MSCA-ITN-ETN;KATHOLIEKE UNIVERSITEIT LEUVEN;BE;"CRYPTOEXPERTS SAS;NXP SEMICONDUCTORS BELGIUM NV;ECOLE NORMALE SUPERIEURE;RUHR-UNIVERSITAET BOCHUM;UNIVERSITY OF BRISTOL;TECHNISCHE UNIVERSITEIT EINDHOVEN;ROYAL HOLLOWAY AND BEDFORD NEW COLLEGE";"FR;BE;DE;UK;NL";;1;0;0;1;0;0 193984;643062;ZENCODE-ITN;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2014-ETN;H2020;Computational and functional annotation of genomic elements during development of the model vertebrate zebrafish;2015-01-01;2018-12-31;;The recent explosion of next generation sequencing (NGS) data has caught Europe unprepared and led to a critical shortage of computational biology expertise. As NGS methods are expected to become pervasive from basic science to personalised medicine there is an urgent need for highly skilled young scientists trained in both computational biology and experimental wet lab biology. Our network addresses this important problem of the postgenomic era. We aim to provide multi-disciplinary skills for a solid foundation in computational biology and developmental genomics. Developmental genomics is central to understanding of ontogeny and many genetic and congenital anomalies, but was outside the scope of the landmark ENCODE and FANTOM projects. ENCODE highlighted the need for an in vivo vertebrate model that enables high throughput in vivo functional testing of hypotheses generated from genome scale annotation. Zebrafish is an ideal model for extending the scope of genomics to vertebrate development. We aim to comprehensively annotate functional elements, decipher genomic codes of transcription, as well as coding and non-coding gene function during development and enhance zebrafish as an attractive developmental, comparative and disease model. The participants include 7 non-academic members (2 of which are beneficiaries), major zebrafish genomics laboratories, eminent computational biologists and world class genomics technology experts active in FANTOM and ENCODE. The training program involves 15 ESRs, more than 40 intersectoral and interdisciplinary secondments totalling 19 months, 7 training courses and 2 workshops/conferences. The main outcome of this programme is a cohort of researchers with computational, experimental laboratory and transferable skills ready to further their career in academia, public health and the private sector.;3724035,89;3724035,89;H2020-MSCA-ITN-2014;/MSCA-ITN-ETN;THE UNIVERSITY OF BIRMINGHAM;UK;"UNIVERSITE DE LIEGE;IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE;RIKEN THE INSTITUTE OF PHYSICAL AND CHEMICAL RESEARCH;GENOME RESEARCH LIMITED;KARLSRUHER INSTITUT FUER TECHNOLOGIE;CONSORCI INSTITUT D'INVESTIGACIONS BIOMEDIQUES AUGUST PI I SUNYER;BGI EUROPE INSTITUTE FOND;KAROLINSKA INSTITUTET;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;KING'S COLLEGE LONDON";"BE;UK;JP;DE;ES;DK;SE";;1;0;0;1;0;0 200706;677776;TranslationRegCode;SIGNED;H2020-EU.1.1.;ERC-StG-2015;H2020;Cracking the Translation Regulatory Code;2016-03-01;2021-02-28;;"Organisms across all kingdoms share several systems that are essential to life, one of the most central being protein synthesis. Living in a continuously changing environment, cells need to constantly respond to various environmental cues and change their protein landscape. In extreme cases, cells globally shut down protein synthesis and upregulate stress-protective proteins. Mechanisms of translational repression or selective enhancement of stress-induced proteins have been characterized, but their effects were demonstrated on an individual mRNA basis. Which target mRNAs are translationally regulated in response to different environmental cues, and what are the cis-regulatory elements involved, largely remain as open questions. Using ribosome footprint profiling, I recently discovered a novel mode of translational control in stress, underscoring the potential of new technologies to uncover novel regulatory mechanisms. But while transcription cis-regulatory elements have been thoroughly mapped in the past decade, and splicing regulatory elements are accumulating, the identification of translation cis-regulatory elements is lagging behind. Here I propose to crack the mammalian translation regulatory code, and close this long-standing gap. I present a novel interdisciplinary framework to comprehensively identify translation cis-regulatory elements, and map their mRNAs targets in a variety of cellular perturbations. Importantly, we plan to explore mechanisms underlying novel cis-regulatory elements, and create the first genome-wide functionally annotated translation regulatory code. The translation regulatory code will map targets of existing mechanisms and shed light on newly identified pathways that play a role in stress-induced translational control. The proposed project is an imperative stepping stone to understanding translational regulation by cis-regulatory elements, opening new avenues in the functional genomics research of translational control.";1587500;1587500;ERC-2015-STG;/ERC-STG;TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY;IL;;;;1;0;0;1;0;0 193277;634200;BIOCASCADES;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2014-EID;H2020;BIOCASCADES- Sustainable and Scalable Biocatalytic Cascade Reactions Training Network;2015-01-01;2018-12-31;;"In BIOCASCADES, nine early-stage researchers (ESRs) will investigate the development of sustainable (chemo)enzymatic cascade reactions under the ‘green chemistry’ philosophy. The proposed BIOCASCADES project combines different techniques such as compartmentalization, protein engineering and reaction engineering in order to develop commercially viable and environmentally benign one pot reactions. By avoiding intermediate downstream- and purification-steps, cascade reactions minimize production costs, energy demand and waste production and are thus expected to make a major contribution for the development of sustainable and efficient production processes. Small- and medium sized enterprises (SMEs) are emerging as main drivers of European Research. They are dynamic, explore new areas and create new ideas, while large companies rely more and more on outsourcing research or involving SMEs by joint ventures. However, small companies are not strong enough as stand-alone enterprises, which requires them to form networks with other SMEs and academia. This creates a strong demand for young researchers who can move freely in an international and interdisciplinary environment. In a tailor-made training program BIOCASCADES aims to provide the nine early stage researchers with specific scientific and transferable skills for careers in the highly dynamic European biotechnology sector. Training at leading laboratories of biocatalysis will develop their scientific skills, while secondments to the industry and specific workshops will develop their entrepreneurship. The graduates of this doctorate program will be highly qualified for collaborative research between European academia and industry. The consortium is formed by leading academic laboratories from biocatalysis and protein engineering together with a network of four innovative biotech companies. By combining their versatile expertise, the consortium can achieve a success that would not be possible in isolated projects.";2787956,64;2787956,64;H2020-MSCA-ITN-2014;/MSCA-ITN-EID;TECHNISCHE UNIVERSITAET GRAZ;AT;"INNOSYN BV;KUNGLIGA TEKNISKA HOEGSKOLAN;EntreChem SL;DSM CHEMICAL TECHNOLOGY R & D BV;TECHNISCHE UNIVERSITAET BRAUNSCHWEIG;VIAZYM BV;RUHR-UNIVERSITAET BOCHUM;UNIVERSIDAD DE OVIEDO;SAROMICS BIOSTRUCTURES AB;UNIVERSITAET GREIFSWALD;UNIVERSITAET BIELEFELD;ENZYMICALS AG";"NL;SE;ES;DE";;1;0;0;1;0;0 193183;633184;SAPHIR;SIGNED;H2020-EU.3.2.;SFS-01b-2014;H2020;Strengthening Animal Production and Health through the Immune Response;2015-03-01;2019-02-28;;"SAPHIR aims to develop vaccine strategies effective against endemic pathogens responsible for high economic losses in livestock in order to strengthen the profitability of food animal systems, improve animal welfare and reduce xenobiotic usage in farming with a One Health perspective. SAPHIR will bring novel vaccine strategies to the market i) at short term, with several promising vaccines brought to demonstration (RTL6), ii) at long term, with cutting edge strategies brought at proof of concept (RTL3) and iii) in line with socio-economic requirements. SAPHIR has selected two representative pathogens of pigs (Porcine Reproductive and Respiratory Syndrome Virus and Mycoplasma hyopneumoniae), chickens (Eimeria and Clostridium perfringens) and cattle (Bovine Respiratory Syncytial Virus, Mycoplasma bovis) to develop generic vaccine approaches applicable to other pathogens. SAPHIR will issue i) knowledge of immune mechanisms of protection, ii) affordable, safe and multivalent vaccines with DIVA properties, iii) efficient adjuvants targeting dendritic cells, optimal formulations, new mucosal and skin delivery systems, a new generation of DNA vectors and viral replicon platforms for fostering an earlier and longer duration of immunity including the perinatal period, and iv) basal biomarkers of individual immuno-competence for future breeding strategies. The SAPHIR dissemination and training programme includes creation of an integrated health management website, launch of a Global Alliance for Veterinary Vaccines and organization of workshops directed at food animal system stakeholders. This will ensure optimal research translation of SAPHIR outputs to market and field applications. SAPHIR brings together interdisciplinary expertise from fourteen academic institutes including a Chinese partner, five SMEs and two pharmaceutical companies.";10549121,5;8999996,25;H2020-SFS-2014-2;/RIA;INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE;FR;"VIRBAC SA;Shanghai Veterinary Research Institute - Chinese Academy of Agricultural Sciences;UNIVERSITE DE LAUSANNE;XEOLAS PHARMACEUTICALS LIMITED;SZKOLA GLOWNA GOSPODARSTWA WIEJSKIEGO;THE ROYAL VETERINARY COLLEGE;UNIVERSITEIT GENT;EUROPEAN FORUM OF FARM ANIMAL BREEDERS;INRA TRANSFERT S.A.;UNIVERSITAET BERN;SVERIGES LANTBRUKSUNIVERSITET;INMUNOLOGIA Y GENETICA APLICADA SA;SPOREGEN LIMITED;VACCIBODY AS;PARCO TECNOLOGICO PADANO S.R.L.;EIDGENOESSISCHES DEPARTEMENT DES INNERN;THE UNIVERSITY OF LIVERPOOL;THE PIRBRIGHT INSTITUTE LBG;THE UNIVERSITY OF EDINBURGH;CARDIFF UNIVERSITY;STICHTING WAGENINGEN RESEARCH";"FR;CN;CH;IE;PL;UK;BE;NL;SE;ES;NO;IT";;1;0;0;1;0;0 203358;677693;SOGICA;SIGNED;H2020-EU.1.1.;ERC-StG-2015;H2020;Sexual Orientation and Gender Identity Claims of Asylum: A European human rights challenge;2016-09-01;2020-08-31;;"This project will generate the first ever theoretically and empirically-grounded comparative and comprehensive picture of the status and legal experiences of asylum-seekers across Europe claiming international protection on the basis of their sexual orientation or gender identity (SOGI), and determine how the European asylum systems can treat more fairly asylum claims based on the claimant’s SOGI. Every year, thousands of individuals claim asylum in Europe based on their SOGI, and more often than not their claims are treated unfairly, especially considering the disproportionately high rate of refusals on these grounds. There have been very limited attempts to address this issue, and this research will overcome this gap by carrying out a study more comprehensive than any other done in this field in the past, and producing outcomes that are unparalleled in terms of their reach. My main objectives are: 1) to analyse how SOGI related claims are adjudicated in different asylum legal European frameworks (EU, CoE, Germany, Italy, UK), and 2) to produce detailed policy recommendations in regard to the national, European Union and Council of Europe asylum adjudication systems, to the effect of developing a system that addresses adequately the socio-cultural, gender identity and sexual diversity of asylum-seekers. For the first time, a combined comparative, interdisciplinary (socio-legal), human rights and empirical approach will be adopted to research this field, which requires a substantial long period of research and sustained funding. This approach ensures the unique character of the findings and their impact on improving the current law, policy and decision-making regarding SOGI asylum claims, which are increasingly under close scrutiny across Europe. I am in a unique position to achieve these objectives, in the light of my experience with publications , projects and NGOs in the field of human rights and refugees from socio-legal, empirical and European perspectives.";1000565;1000565;ERC-2015-STG;/ERC-STG;THE UNIVERSITY OF SUSSEX;UK;THE UNIVERSITY OF LIVERPOOL;UK;;1;0;0;1;0;0 203511;707840;SpiL;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-GF;H2020;Spillover of Leptospira in island populations of the Channel Island fox;2017-10-01;2020-09-30;;Spillover, or cross-species transmission, of pathogens from wildlife to humans is the major cause of emerging infectious diseases such as HIV, Ebola virus or SARS. Yet despite this relevance spillover as a natural process is little known, and there is a pressing need for general theory on spillover. We propose to develop a new conceptual framework for spillover, by using an interdisciplinary approach to analyse an exceptionally complete dataset of Leptospira spillover from California sea lions to endangered Channel Island foxes. Guided by the OneHealth vision, we will combine concepts and methods from human epidemiology, disease ecology and island biology to create a model of Leptospira spillover risk that will provide a unique opportunity to develop and extract general concepts. Through this process, Borremans, the applying experienced researcher, will acquire a strong set of skills that will boost his expertise and significantly advance his professional profile. He will be guided by two high-profile researchers, Lloyd-Smith (UCLA) and Hens (UHasselt) and will benefit from collaborations through their extensive international networks, ensuring Borremans’ visibility at an international level.;240530,4;240530,4;H2020-MSCA-IF-2015;/MSCA-IF-GF;UNIVERSITEIT HASSELT;BE;;;;1;0;0;1;0;0 203212;675006;SE2B;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2015-ETN;H2020;Solar Energy to Biomass - Optimisation of light energy conversion in plants and microalgae;2016-03-01;2020-02-29;;"In the face of the increasing global consumption of fossil resources, photosynthetic organisms offer an attractive alternative that could meet our rising future needs as clean, renewable, sources of energy and for the production of fine chemicals. Key to the efficient exploitation of these organisms is to optimise the conversion of Solar Energy into Biomass (SE2B). The SE2B network deals with this optimisation in an interdisciplinary approach including molecular biology, biochemistry, biophysics and biotechnology. Regulation processes at the level of the photosynthetic membranes, integrating molecular processes within individual proteins up to flexible re-arrangements of the membranes, will be analysed as a dynamic network of interacting regulations. SE2B will yield information about the similarities and differences between cyanobacteria, green algae, diatoms and higher plants, the organisms most commonly employed in biotechnological approaches exploiting photosynthetic organisms, as well as in agriculture. The knowledge gained from understanding these phenomena will be directly transferred to increase the productivity of algal mass cultures for valuable products, and for the development of sophisticated analytic devices that are used to optimise this production. In future, the knowledge created can also be applicable to the design of synthetic cell factories with efficient light harvesting and energy conversion systems. The SE2B network will train young researchers to work at the forefront of innovations that shape the bio-based economy. SE2B will develop a training program based on individual and network-wide training on key research and transferable skills, and will furthermore disseminate these results by open online courses prepared by the young researchers themselves.";3866945,22;3866945,22;H2020-MSCA-ITN-2015;/MSCA-ITN-ETN;JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN;DE;"UNIVERSITA DEGLI STUDI DI VERONA;STICHTING VU;COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES;UMEA UNIVERSITET;UNIVERZITA PALACKEHO V OLOMOUCI;PSI (PHOTON SYSTEMS INSTRUMENTS), SPOL. SRO;WAGENINGEN UNIVERSITY;RIJKSUNIVERSITEIT GRONINGEN;QUEEN MARY UNIVERSITY OF LONDON;PHYCOSOURCE;TURUN YLIOPISTO";"IT;NL;FR;SE;CZ;UK;FI";;1;0;0;1;0;0 202904;704848;CF_struct;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;High-Resolution X-ray Structures of Full-Length Cystic Fibrosis Transmembrane Conductance Regulator;2016-11-16;2018-11-15;;This proposal seeks to solve the high-resolution X-ray crystal structure of full-length Cystic Fibrosis Transmembrane Conductance Regulator (CFTR), an anion channel which regulates chloride ion concentration at the lumen-exposed surface of epithelial cells. Mutations of the CFTR gene cause cystic fibrosis (CF), a lethal disease which results in bowel obstruction, lung disease and premature death. CFTR is an ATPase and a member of the ATP-Binding Cassette (ABC) transporter family of proteins which has an allosteric Regulatory (R) domain not found in other ABC transporters. From the structure of CFTR, its mode of action will be revealed, focusing on the two sites of ATP hydrolysis and key residues for channel gating. CFTR will be crystallized alone and in the presence of the pharmacological agent Kalydeco, a small molecule from Vertex Pharmaceuticals that is used for the treatment of CF and reduces CF symptoms. The initial high-resolution X-ray crystal structure is a foundation from which personalized drug design work can begin. Therefore, the Kalydeco-CFTR complex structure will be used for ligand optimization of Kalydeco, an iterative process which will improve Kalydeco’s specificity and pharmacokinetics. The latest technology, including in meso in situ serial crystallography and X-ray free electron lasers for serial femtosecond crystallography will be used as well as traditional synchrotron X-ray sources. These Actions use an interdisciplinary mix of crystallography, chemistry, biochemistry, biophysics and computational structural determination programs. The work will take place in Ireland in the lab of Dr. Martin Caffrey at Trinity College Dublin, a distinguished researcher in the field of membrane structural and functional biology. The prestigious Marie Sk³odowska-Curie fellowship will enable the candidate to actualize many objectives outlined in her career development plan in order to become an independent researcher.;175866;175866;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN;IE;;;;1;0;0;1;0;0 203135;708507;AGERISK;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Neurocomputational mechanisms underlying age-related performance changes in goal-directed decisions from experience;2016-09-01;2019-03-02;;The ability to make goal-directed decisions concerning one’s general well-being declines in later life. The primary—and potentially improvable—factor impacting this decline in decision-making performance is the learning process that precedes a decision. However, little is known about age-related changes in the neurocomputational mechanisms that underlie these learning processes. The goal of the proposed project is to identify these changes. The project will first identify age-related variability in decision-making performance across individuals and task environments, and then test what computational models from artificial intelligence best explain this variability. Because previous research has shown that decision-making performance declines as the complexity of the choice environment increases, the focus will be on performance in cognitively demanding environments that require goal-directed decisions from experience. The project will combine data from lab-based and home-based neurocognitive experiments, capitalizing on new developments in online experiments and webcam based eye tracking. The applicant’s unique research background brings the interdisciplinary range of skills together that is required for the project, combining experience in computational modelling techniques from artificial intelligence, large-scale data analysis from computational linguistics, and neurocognitive experiments. The proposed project promises to further the scientific understanding of the functional link between aging and decision-making performance. Its findings will ultimately help to empower aging decision makers to navigate cognitively demanding choice environments.;171460,8;171460,8;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;FREIE UNIVERSITAET BERLIN;DE;;;;1;0;0;1;0;0 203181;713567;EDGE;SIGNED;H2020-EU.1.3.4.;MSCA-COFUND-2015-FP;H2020;Cutting Edge Training - Cutting Edge Technology;2016-06-01;2021-05-31;;"EDGE is a training and development programme of scientific excellence for postdoctoral researchers that offers a unique combination of disciplines and industry engagement to the 71 fellows it will recruit. Leveraging the strengths and assets of three Irish National Research Centres, AMBER, CONNECT and ADAPT, headquartered in TCD, EDGE will form the next generation of thought leaders in ICT. AMBER offers expertise in advanced materials that will play a pivotal role in future systems and devices. CONNECT’s focus is on future networks that will underpin the services the world needs and ADAPT brings cutting-edge expertise in digital content. EDGE researchers will work at the interface between these Centres and will generate highly interdisciplinary projects, adding value to all. Most importantly, industry will have a primary role in defining, running and supporting the projects, and will take an active part in developing the scientists, through secondments, industry events and specialised training. Applying the principles of the Charter and Code throughout the programme, the EDGE selection process is guided by the principles of Excellence, Transparency, Fairness and Impartiality. Candidates will submit proposals and fellows will be selected following an open, transparent, merit-based, impartial and equitable selection procedure, based on international peer review. EDGE offers the possibility of building skills that will address a clearly identified skills shortage across Ireland and Europe. EDGE will impact Europe through the development of a unique cohort of excellent, cross-disciplinary fellows who will have the capability of managing multidisciplinary, industrial research problems. On completion of their fellowship they will have the skillset to enter the European workforce to deliver innovation and enhance European Industrial Competitiveness across the entire spectrum from materials to content.";12177600;6088800;H2020-MSCA-COFUND-2015;/MSCA-COFUND-FP;THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN;IE;;;;1;0;0;1;0;0 201089;702970;PAEDS;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Prevalence and Experience of Diagnostic Shifts in Youth Mental Healthcare;2017-09-01;2019-08-31;;Epidemiological data shows that psychiatric diagnoses in childhood have limited temporal continuity. Over the course of a child’s contact with mental health services, a diagnosis received at one time can transition into a different diagnostic classification or be lost entirely. Such shifts can have profound implications for young people and their families, given the significance invested in diagnostic labels as a means of making sense of emotional and behavioural difficulties. However, no research has investigated the prevalence of diagnostic shift in Child & Adolescent Mental Health Services (CAMHS) or explored how it is experienced by the children and families affected. PAEDS aims to provide the first such evidence through a two-stage mixed-methods design. First, a review of clinical records in an Irish CAMHS service will establish the frequency with which diagnostic shifts occur and the typical patterns through which they manifest. Second, qualitative interviews will be conducted with children and parents who have experienced diagnostic shift, to establish the narratives through which people make sense of these changes and the implications for self-concept, social identity and service engagement. To exploit the social and clinical value of the results, a Delphi process will be initiated that engages a diverse panel of stakeholders in developing evidence-based resources that help service-providers and service-users adapt to diagnostic shift. The project will thereby promote sensitive, patient-centred youth mental health policy and practice. It will also provide a platform for me to build a career pioneering the interdisciplinary study of how scientific and clinical classifications interact with identity. By fully integrating a tailored Personal Career Development Plan into the action programme, I will capitalise on the MSCA’s opportunity for the strategic development of skills and competencies valued in the current academic environment.;175866;175866;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN;IE;;;;1;0;0;1;0;0 201328;705437;NextGEnergy;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Next Generation Power Sources for Self-sustainable Devices – Integrated Multi-source Energy Harvesters;2016-06-01;2018-05-31;;"In recent years, various energy harvesting techniques have been realised to overcome shortcoming of batteries in terms of lifespan, overall cost-effectiveness and chemically safe electronics. Energy harvesters convert different forms of environmental energies into electricity thus making devices self-powered. However, with over a decade’s development, energy harvesters have not been able to overtake batteries yet, although academia and industry are keen to apply it in electronics. One of the reasons is that the power level provided by a single-source energy harvester, which most research has been focused on, is not high or stable enough. Therefore, a crucial and urgent question has been raised – how to release the huge potential of energy harvesting technology? This proposed action is addressing the above scientific/engineering question by exploring multi-source energy harvesting on a single piece of material. Perovskite structured materials are able to exhibit piezoelectric, pyroelectric or photovoltaic effect which has been utilised to harvest kinetic, thermal or solar energy separately. This action will combine these three effects on the same perovskite for the first time ever. Solid-state reaction will be used to synthesise the materials; thick- and thin-films will be deposited through physical methods; the materials and films will be structurally analysed, multi-functionally evaluated and compositionally optimised, to establish new inter principles of kinetic-thermal-solar multi-harvesting. Such a research topic of multi-functional materials and devices is also a ‘‘roadmap’’ of the European Science Foundation. It will conduct an interdisciplinary research across piezoelectricity, pyroelectricity and photovoltaics, and will require contributions from materials science, electronics and chemistry. Positive outcome of this action will lead to a breakthrough in the development of self-sustainable devices, and thus leading to a revolution in smart human societies.";191325,6;191325,6;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;OULUN YLIOPISTO;FI;;;;1;0;0;1;0;0 200459;705939;epiGERMetics;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Landscape of epigenetic control in early and late germ line development;2016-03-01;2018-10-02;;Germ cells have unique role in development. They are the only cells required for the transmission of genetic material from generation to generation in sexually reproducing organisms. This makes them pivotal for the survival of species and ultimately for the propagation of life. Although germ cells undergo extensive cellular differentiation during gametogenesis, they are protected from somatic reprogramming. This requires precise control of transcriptional programs, misregulation of which leads to infertility and developmental defects. Moreover, germ cell-like properties acquired ectopically promote tumor formation. My aim is to understand how germ cell identity is controlled in vertebrates, using zebrafish as a genetic model. My hypothesis is that epigenetic control of gene expression is regulated in both the nucleus and cytoplasm of germ cells. In the nucleus, Polycomb Group (PcG) proteins regulate transcription by establishing repressive chromatin modifications. In the germ cytoplasm, translational regulation by Argonaute proteins, involved in RNA silencing pathways, is pivotal for maintaining germ cell identity. However, the events that facilitate cross-talk between the nucleus and germ cytoplasm are not known. Here, I propose to combine high-end developmental biology techniques with state-of-the art genomic technologies to investigate the cooperation between the PcG complex and Argonaute proteins during germ line development. I believe that the crossing point between my scientific interest (events outside the nucleus) and the expertise of my supervisor (regulation in the nucleus), creates a very solid background for this proposal. It will further develop my interdisciplinary skills and enhance my creative potential by allowing me to look at the regulation of germ cell identity from different angles. I am confident, that this proposal is the perfect stepping stone in becoming an independent scientist and an expert in the field of epigenetic gene regulation.;177598,8;177598,8;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;STICHTING KATHOLIEKE UNIVERSITEIT;NL;;;;1;0;0;1;0;0 200443;703495;IMMIGRANTS;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;The Effects of Media News about Immigrants on Majority’s Attitudes and Behaviors towards Immigrants;2017-01-01;2019-07-23;;The interdisciplinary IMMIGRANTS project aims at a better understanding of how media influence majority’s attitudes and behaviors towards immigrants – a socially pressing issue connected to rapid expansion of immigration in Europe. In the project, I will focus on different aspects of media news – their valence, labels used for immigrants’ ethnicity and pictures of immigrants accompanying media articles about immigrants. The first goal of my research is to investigate how different labels used for immigrants’ ethnicity (nouns vs. adjectives) combined with different valence of media articles about immigrants (positive vs. negative vs. ambivalent) influence participants’ attitudes and behaviors towards immigrants. My second goal is to compare the effects of articles accompanied by different images of immigrants and articles without such images on participants’ attitudes and behaviors towards immigrants. Both goals feature a number of tasks related to the effects of media articles on attitudes and behaviors towards immigrants: I will test underlying mechanisms (e.g., biometrically tracked positive and negative emotions) and boundary conditions (e.g., social status and category salience of an immigrant group, participants’ intergroup contact with immigrants) of these effects. In three studies of the IMMIGRANTS project, I bring together different traditions on media and immigrant research and address several gaps in social scientific literature (e.g., too narrow focus on negative media news in political and media research, too narrow focus on positive intergroup contact and self-reported emotions in psychology). The outcome of IMMIGRANTS can be used to inform guidelines for professional training of journalists, policy makers, and social workers to become more sensitive to the impact of language describing immigrants.;187419,6;187419,6;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;UNIVERSITAET BERN;CH;;;;1;0;0;1;0;0 200211;707270;WISLAS;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Warmed Icelandic Soils, Lipids and Sequencing: towards a better understood climate proxy;2016-10-01;2018-11-30;;The distribution of the soil bacterial membrane lipids “branched glycerol dialkyl glycerol tetraethers” (brGDGTs) in geological records has been used to reconstruct palaeoclimatic conditions, specifically the mean annual air temperature and soil pH. However, the large error associated with the most recent brGDGT-based calibration, makes this method unsuitable for determining absolute temperatures. The fellow aims to perform geochemical and microbiological work that will result in the improvement of this palaeotemperature proxy. Firstly, an improved analytical method will be used, targeting not only fifteen brGDGTs that are currently used for palaeoclimate reconstructions, but including an additional fifteen brGDGT lipids, and a suite of precursors, whose diversity in soils is unstudied. This extended dataset will be measured in a well-studied, naturally (geothermally) warmed soil, linking the observed lipid distributions directly to the measured in-situ soil temperature (covering a 0-35°C gradient). Furthermore, the applicability of the novel temperature proxy proposed, will be tested in a well-studied dataset of European soils, covering a latitudinal temperature gradient. Although environmental studies point towards the Acidobacteria as the source organism, only one brGDGT has been found in an Acidobacterial culture so far and brGDGTs are still considered to be “orphan lipids”. Using a novel approach to identify the source organism, the fellow proposes to study the microbial community using a next-generation sequencing method. Tracking the patterns in (Acido)bacterial distribution along a temperature gradient, will enable the fellow to ascertain if the changes in the brGDGT pool are caused by a shift in the microbial community, or are caused by phenotypic plasticity. This interdisciplinary project will improve the accuracy and interpretation of lipid-based palaeoclimate reconstructions and will extend the applicant’s scientific experience and career perspectives.;172800;172800;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;UNIVERSITEIT ANTWERPEN;BE;;;;1;0;0;1;0;0 199931;690974;MIREL;SIGNED;H2020-EU.1.3.3.;MSCA-RISE-2015;H2020;MIREL - MIning and REasoning with Legal texts;2016-01-01;2019-12-31;;"The management of large repositories of norms, and the semantic access and reasoning to these norms are key challenges in Legal Informatics. The MIREL project will create an international and inter-sectorial network to define a formal framework and to develop tools for MIning and REasoning with Legal texts, with the aim of translating these legal texts into formal representations that can be used for querying norms, compliance checking, and decision support. The development of the MIREL framework and tools will be guided by the needs of three industrial partners, and validated by industrial case studies. MIREL promotes mobility and staff exchange between SMEs to academies in order to create an inter-continental interdisciplinary consortium in Law and Artificial Intelligence areas including Natural Language Processing, Computational Ontologies, Argumentation, and Logic & Reasoning. MIREL addresses both conceptual challenges, such as the role of legal interpretation in mining and reasoning, and computational challenges, such as the handling of big legal data, and the complexity of regulatory compliance. It bridges the gap between the community working on legal ontologies and NLP parsers and the community working on reasoning methods and formal logic. Moreover, it is the first project of its kind to involve industrial partners in the future development of innovative products and services in legal reasoning and their deployment in the market. The European MIREL partners are key players in the communities of Deontic, AI & Law, and the Semantic Web, communities that have traditionally been strong in Europe. The MIREL consortium brings these scientists together with researchers with expertise traditionally lacking in Europe, such as norm and argument mining (Argentina, Japan and China), description logic for reasoning about legal ontologies (South Africa), natural language semantics of deontic modals (US), and the complexity analysis of regulatory compliance (Australia).";1264500;1152000;H2020-MSCA-RISE-2015;/MSCA-RISE;UNIVERSITE DU LUXEMBOURG;LU;"INSTITUT NATIONAL DE RECHERCHE ENINFORMATIQUE ET AUTOMATIQUE;DLVSYSTEM SRL;UNIVERSITA DEGLI STUDI DI TORINO;NOMOTIKA SRL;APIS HRISTOVICH EOOD;ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA;THE UNIVERSITY OF HUDDERSFIELD";"FR;IT;BG;UK";;1;0;0;1;0;0 199947;691185;COMPASS;SIGNED;H2020-EU.1.3.3.;MSCA-RISE-2015;H2020;Colloidal Nanomaterials for Smart Applications;2016-03-01;2020-02-29;;"'The COMPASS project unites key players in Europe and the US with the aim to advance the field of colloidal nanocrystal (NC) synthesis and assembly and their exploitation in photonics, sensing, energy conversion and medicine. COMPASS aims to (i) develop colloidal NCs with desired properties by controlling their size, shape and composition, and to demonstrate routes allowing for large production volumes with nearly identical size and shape; (ii) develop approaches for NC self-assembly in ordered superlattices constituting NC solids with novel properties; (iii) understand the optoelectronic properties of novel NC-based materials by advanced optical and scanning probe spectroscopy methods, and explore pathways for their implementation in light emission, sensing, energy conversion and medicine; (iv) establish a consolidated network between leading EU and US institutes to provide a stimulating international environment for talented young researchers; (v) advance the level of R&D in Europe and the US and foster technology transfer and dissemination; (vii) raise the awareness of the general public on the prospects of NC materials in future technologies. Young scientists will be formed by 'training by research' in long term stays at host labs and by lecture series held in the network that cover specific research topics, technology transfer and management/communication skills, leading to an interdisciplinary and international formation. The exchange will consolidate existing initial links between some of the lead scientists in COMPASS and establish a long lasting network that will have strong impact on science and education with significant repercussions in industry. The work plan is divided in 5 strongly linked workpackages that deal with Management, NC Fabrication, Self Assembly and Surface Functionalization, Photonics and Optoelectronics, and Energy Conversion. COMPASS will be guided by an executive board that consists of the coordinator and the lead PIs of the partners.'";859500;859500;H2020-MSCA-RISE-2015;/MSCA-RISE;FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA;IT;"LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN;UNIVERSITEIT GENT;UNIVERSITEIT UTRECHT";"DE;BE;NL";;1;0;0;1;0;0 200387;678120;RobSpear;SIGNED;H2020-EU.1.1.;ERC-StG-2015;H2020;Robust Speech Encoding in Impaired Hearing;2016-10-01;2021-09-30;;"The prevalence of hearing impairment amongst the elderly is a stunning 33%, while the younger generation is sensitive to noise-induced hearing loss through increasingly loud urban life and lifestyle. Yet, hearing impairment is inadequately diagnosed and treated because we fail to understand how the components that constitute a hearing loss impact robust speech encoding. A recent and ground-breaking discovery in animal physiology demonstrated the existence of a noise-induced hearing deficit -cochlear neuropathy- that coexists with the well-studied cochlear gain loss deficit known to degrade the audibility of sound. Cochlear neuropathy is thought to impact robust encoding of the audible portions of speech and occurs before standard hearing screening methods indicate problems, implying that a large group of noise-exposed people with self-reported hearing problems is currently not screened, nor treated. To design effective hearing restoration strategies, it is crucial to understand how cochlear neuropathy interacts with other hearing deficits to affect robust speech encoding in every-day listening conditions. Through an interdisciplinary approach, RobSpear targets hearing deficits along the ascending stages of the auditory pathway to revolutionize how hearing impairment is diagnosed and treated. RobSpear can yield immense reductions of health care costs through effective treatment of currently misdiagnosed patients and studies the impact of noise-induced hearing deficits on our society. To achieve this, RobSpear: (i) Builds a hearing profile that, based on a computational model of the auditory periphery, develops physiological measures that differentially diagnose hearing deficits in listeners with mixtures of deficits. (ii) Designs individually tailored speech enhancement algorithms that work in adverse conditions and target perceptually relevant speech features, using an unprecedented validation approach that combines novel psychoacoustic and physiological metrics.";1499780;1499780;ERC-2015-STG;/ERC-STG;UNIVERSITEIT GENT;BE;CARL VON OSSIETZKY UNIVERSITAET OLDENBURG;DE;;1;0;0;1;0;0 221509;829208;InWingSpeak;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;From Insect Wings to Miniature Loudspeakers - A Bionic Modelling Approach;2019-04-01;2021-03-31;;"Crickets and bush-crickets use their wings to produce a wide range of often impressively loud courtship songs highly variable in pitch and temporal patterns. The wings of these insects have evolved to be miniaturised and optimised resonators in order to radiate their highly amplified acoustic signals and therefore offer unique solutions for efficient, light-weight acoustic transducers. Here, I propose a novel combination of state-of-the-art bioacoustic and imaging techniques (among others, laser Doppler vibrometry and micro-computational tomography), comparative morphology and two independent but complementary mathematical modelling approaches (agent-based as well as finite element modelling) to investigate the biomechanic and bioacoustic system properties of cricket and bush-cricket wings. By applying these multidisciplinary techniques and methods to a variety of wings, I will derive mechano-acoustic system properties that will allow unravelling of the relationship between wing morphology and emerging resonance properties underlying sound production. The resulting knowledge, combined with modern modelling and simulation techniques and in silico artificial wing evolution towards desirable acoustic properties, will guide engineers in the acoustic design of innovative, biomimetic miniature loudspeakers as used in, e.g., hearing aids. Furthermore, the project results and the proposed scientific and transferable skills training will positively impact on my career development, contributing the building blocks of my future career as an independent, interdisciplinary researcher and future group leader, successfully combining bioacoustics and its evolution with bioinspired innovations for modern acoustic technologies.";174167,04;174167,04;H2020-MSCA-IF-2018;/MSCA-IF-EF-ST;UNIVERSITAET GRAZ;AT;;;;1;0;0;1;0;0 221717;835907;CLEAN;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Well-Confined Mucosal LasEr Ablation with a Negative Pressure Based Endoscopy Capsule;2019-04-01;2021-03-31;;This proposal is an interdisciplinary research action. The objective of the CLEAN project is to develop a novel endoscopic capsule design and to build a prototype endoscopy system using this capsule, which provides local ablation to the superficial layer of target mucosal tissue with sufficient depth to remove abnormal tissue. However, this depth will be shallow enough to avoid the residual effects of therapy within deeper tissue layers. The specific aims are: Aim-1: To develop a computer modelling to mimic the thermal dynamics of the capsule. It is to characterize the total heat energy needed to successfully ablate the lining layer, an adequate sliding speed along the oesophagus, an adequate therapy time for effective thermal target layer ablation, and the amount of thermal injury induced to the various oesophagus layers. Aim-2: To develop the configuration of the capsule in a computer-aided design program. This original design simply extends the target layer above and away from its underlying layers to achieve a well-confined therapeutic effect by delivering vacuum force. With the confinement of therapeutic effect, it is aimed that deeper tissue structures are partially separated from ablation region. Aim-3: To construct and optimize a prototype-level endoscopy system for pre-clinical ex-vivo tissue trials. A high power, 1380-nm diode laser will be used for the therapeutic photothermal ablation. Aim-4: To investigate the feasibility of the design and to evaluate the performance of the prototype system in ex-vivo sheep oesophagus model. Tissue samples will be collected for histology examination to validate the performance goals of the device.;157355,52;157355,52;H2020-MSCA-IF-2018;/MSCA-IF-EF-RI;IZMIR BIYOTIP VE GENOM MERKEZI;TR;;;;1;0;0;1;0;0 221526;843998;DNA-bots;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Enzyme-powered DNA nanorobotic devices;2019-04-01;2021-03-31;;WHY: Enzyme-powered nanorobotic devices are able to self-propel thanks to the conversion of a substrate into products, holding a great potential for biomedical applications. A step forward in the field would be the precise control and design over the structure and enzyme spatial configuration, as well as the integration of complex functions. WHAT: DNA-bots is an interdisciplinary approach in which enzyme-propulsion and DNA nanotechnology will be merged to develop a new class of biocompatible and biodegradable nanorobotic devices able to self-propel, sense and actuate in front of specific stimuli. To achieve this goal, I will undertake a high risk/high gain research approach at the forefront of nanotechnology. The leading idea is to design and fabricate DNA nanostructures which will be site-specifically functionalized with enzymes to generate self-propulsion. The enzyme-powered DNA nanorobots will be further engineered by integrating DNA nanoswitches able to sense and perform loading and release of cargoes upon specific stimuli. HOW: The challenge met by this Project is to provide a groundbreaking contribution to DNA nanotechnology and nanorobotics. To achieve these objectives, I will be trained at the Host group led by Prof. Francesco Ricci (University of Rome Tor Vergata, Italy), which is a young and dynamic team at the vanguard of the use of DNA nanotechnology for sensing and drug-delivery applications. The Fellowship will proceed through a well-defined set of research and training tasks, organized into four work packages. Thanks to this MSCA Fellowship, I will continue expanding my scientific knowledge and acquiring cutting-edge skills (in synthetic biology, DNA nanotechnology, and nanorobotics), which will significantly impact my career as a researcher and help me to strenghten my position as an independent and mature researcher.;183473,28;183473,28;H2020-MSCA-IF-2018;/MSCA-IF-EF-ST;UNIVERSITA DEGLI STUDI DI ROMA TOR VERGATA;IT;;;;1;0;0;1;0;0 221581;837838;WEAVERBIRD_DEFENCE;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Unravelling an extended phenotype: sexual selection and the evolution of nest architecture in weaverbird defence against brood parasitism;2019-07-08;2022-07-07;;A major challenge for evolutionary biologists is to explain how selection maintains biodiversity. Coevolution between closely associated species contributes substantially to the diversity of life. Yet little is known about how coevolutionary pressures between different species interact with selection from intraspecific social interactions. I will address this fundamental gap in our knowledge by analysing how sexual selection interacts with the evolution of host defences against a brood parasite. Cuckoos and their hosts provide a textbook example of coevolution, by reciprocally selecting for better parasitic tricks or better host defences. I will determine whether sexual selection influences the trajectory and pace of coevolutionary change and investigate whether this is why similar coevolutionary arms races have such diverse outcomes. The weaverbirds and their brood parasite the Diederik cuckoo provide an unrivalled opportunity to test this hypothesis given that weaverbirds exhibit a sexually-selected extended phenotypic trait: an elaborate nest that the females choose before mating with the male and laying in his nest. This trait also potentially doubles as a deterrent to brood parasites, by preventing them from gaining access to the nest. Second, this trait can be precisely quantified by applying state-of-the-art computational and analytical techniques to this novel context. Third, populations of weaverbirds have been introduced to islands where they have existed in the absence of selection from brood parasitism for over one hundred generations, providing the opportunity to partition out effects of different selection pressures. With this interdisciplinary approach I will investigate whether nest architectural defences have evolved to combat brood parasitism, how the evolution of these defences interacts with sexual selection, and how the evolution of nest architecture influences the evolution of other forms of defence against brood parasites.;289732,8;289732,8;H2020-MSCA-IF-2018;/MSCA-IF-GF;THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;UK;;;;1;0;0;1;0;0 221625;846810;TaPPiNG-EPI;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Targeting Purinergic Pathway in drug-resistant epilepsy using human Neurons and Glia.;2019-04-01;2021-03-31;;Epilepsy is a neurological disorder characterized by recurrent seizures affecting 65 million people worldwide of which 6 million live in Europe alone with around 30% of patients not responding to currently available treatment. The ATP-gated P2X7 receptor (P2X7R) has recently emerged as a promising target for epilepsy, showing anticonvulsant and disease-modifying properties in animal models. However, to develop P2X7R-based therapeutics the cell types involved in pathological P2X7R activation must be determined, and whether results from rodent models can be replicated in human tissue must be tested. Using human induced pluripotent stem cell-derived neurons and glia and resected brain tissue from epileptic patients, TaPPiNG-EPI proposes to investigate the cell-specific alterations and pathological contribution in the P2X7R pathway and pharmacological targeting of hyperexcitability using P2X7R antagonists. These studies will be complemented by the investigation on the alterations in P2X7R pathway in GFP-P2X7 reporter mice available in the host institution (RCSI). Through international secondments and intersectoral collaborations TaPPiNG-EPI brings together experts in purinergic signalling, industrial partners, epilepsy clinicians as well as leading European academic labs with diverse expertise. The interdisciplinary and intersectoral components of TaPPiNG-EPI combined with international collaborations and secondments in academia, the excellent training record of the supervisor and RCSI and the outstanding resources for learning and development available at RCSI will give me the tools necessary to achieve research independence and my transition to a highly employable future neuroscientist with a focus on epilepsy.;196590,72;196590,72;H2020-MSCA-IF-2018;/MSCA-IF-EF-ST;ROYAL COLLEGE OF SURGEONS IN IRELAND;IE;;;;1;0;0;1;0;0 221698;838776;StringyGeometry;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Stringy geometry: quantum corrections and the fate of string compactifications from spacetime and the worldsheet;2020-09-01;2023-08-31;;"This project uses newly developed geometric structures to understand quantum corrections in string theory from both a worldsheet and spacetime perspective. The major goal is to prove that supergravity solutions with flux can be quantum corrected to give consistent string compactifications. I will also investigate whether these new geometric structures can shed light on strongly coupled heterotic worldsheet models. I will do this by combining my experience with the mathematics that underlies flux compactifications with insights from supergravity and worldsheet methods. This will greatly expand my knowledge in both physics and mathematics and bring me into close working relationships with researchers at the University of Chicago and Sorbonne Universite. The key difference between my approach and existing work is the use of newly developed techniques in differential geometry that provide a unified framework for analysing flux compactifications - in particular, generalisations of G-structures within generalised geometry. The proposed research tackles a fundamental problem: we do not know whether the many supergravity solutions used in phenomenology or AdS/CFT define honest string theory solutions. One output of this project will be a natural language for stringy corrections - this has applications in formal aspects of string theory and phenomenology, including moduli stabilisation, finding new non-Kahler heterotic solutions and the existence of de Sitter vacua. Progress on any one of these would be an valuable contribution to the most important problems in the field, ensuring the ongoing international competitiveness of theoretical physics in the EU. The proposed research is interdisciplinary due to considerable overlap with differential geometry and conformal field theory. The proposal includes plans for transfer of knowledge between the applicant and the host institutions, acquisition of new knowledge areas, professional development and outreach.";257619,84;257619,84;H2020-MSCA-IF-2018;/MSCA-IF-GF;SORBONNE UNIVERSITE;FR;;;;1;0;0;1;0;0 221530;839111;HepEDOT;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Conductive, self-doping and biodegradable oligoEDOT-heparin biomaterial for improved electromechanical coupling, cardiac cell retention and delivery of paracrine factors;2019-04-01;2021-03-31;;Cell therapy has emerged as a promising therapeutic strategy for cardiac repair, showing modest cardiomyocyte protection and infarct size reduction. It is under debate whether these outcomes are due to the implanted cells or their paracrine factors, as cells are scarce within a few weeks post-implantation. Regardless, this is still not sufficient to promote cardiac remuscularization and reverse medium to severe myocardium injury and fibrosis. Improved cell retention has been achieved with a substantial bulk of implanted cells, but highly associated to graft-induced arrhythmia, representing a significant challenge for clinical translation. The present study seeks to promote cardiac remuscularization after infarct, by improving the retention of cardiac cells and their paracrine factors without causing graft-induced arrhythmia. To do so, a conductive, self-doping and biodegradable oligoEDOT-heparin biomaterial will be synthesized and studied on in vitro and in vivo cardiac infarct models. The conductive EDOT oligomer moiety is envisaged to act as an electrical sink to shield the cardiac tissue from mismatched electromechanical impulses, while heparin will facilitate cardiac cell support and loading of regenerative factors, besides its recently documented doping capacity. The results of this fellowship are expected to overcome low cell retention and graft-induced arrhythmia, two of the biggest obstacles for translation in cardiac cell therapy, but also contribute with new insights regarding conductivity in materials and biological systems, to multiple fields of materials chemistry, medicine and bioelectronics. The world-class academic environment, collaborations and combined interdisciplinary expertise in biomaterials and cardiovascular sciences make the proposed fellowship activities ideally placed for enhancing my career prospects and consolidating my host and Europe in a leading position for translational research.;224933,76;224933,76;H2020-MSCA-IF-2018;/MSCA-IF-EF-ST;IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE;UK;;;;1;0;0;1;0;0 221595;837297;The Damned;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Algeria, antifascism, and Third Worldism: An anticolonial genealogy of the Western European New Left (Algeria, France, Italy, 1957-1975);2020-01-13;2023-01-12;;"THE DAMNED proposes a new study of the genealogy of the New Left in Western Europe from the mid-1950s to the mid-1970s. Breaking with current interpretations, the project reframes the European political geography to include the (post)colonial space, and reassesses the historical influence of the Algerian War of Independence (1954–1962) – and Third Worldism more generally – in the genealogy of the new political cultures that flourished during the ‘long 1960s’, associating a renewed antifascism with anticolonial struggles. Bringing together disciplines and methodologies from across a number of humanities and social sciences, THE DAMNED will produce a case study (focusing on Algeria, France and Italy) setting out new approaches to understanding the emerging of the New Left as a complex process encompassing local, national and transnational dynamics; a process shaped by, but also shaping, decolonisation. The goal is to contribute – at least – to complicating the Western narrative of the global 1960s, by shifting the focus from Berkeley and Paris to Algiers. THE DAMNED is to be carried out mostly in Algeria, with a secondment in France and a return phase in Italy. Working with leading experts in each of these countries, the aim is to develop a truly transnational, interdisciplinary network exploring anew the global 1960s. By means of an extensive oral history project interviewing anticolonial activists, THE DAMNED will create a repository of sources for researchers, with a selection of interviews accessible online. THE DAMNED has been designed to ensure a mutually beneficial exchange of knowledge between the researcher and the third country (Algeria): ‘The challenge is to improve the design of cultural experiences by enhancing participatory and collaborative approaches and by fostering mutual cultural understanding and resilient strategies’, as stated in the H2020 Work Programme 2018–20.";221605,44;221605,44;H2020-MSCA-IF-2018;/MSCA-IF-GF;UNIVERSITA CA' FOSCARI VENEZIA;IT;;;;1;0;0;1;0;0 221534;846470;MechanoGenetic;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Role of mechanical forces in cell-matrix adhesion sites;2020-01-01;2021-12-31;;"Cells in our bodies constantly experience mechanical forces from their microenvironment. When cells sense a critical threshold of elevated tension, they hold tight together and allow tissues to function healthily as a group. In certain diseases, however, our cells lose their mechanosensing and adhesive properties and, as a result they get dissociated, as in the case of muscular dystrophies. Integrin-based adhesions to the extracellular matrix (ECM) are emerging as key networks of mechanotransmission. This proposal aims to discover how mechanical forces modulate cell-matrix adhesion at the myotendinous junctions in the developing Drosophila embryo, combining biophysical, molecular and genetic approaches. To achieve this goal, I propose to implement two complementary specific objectives: First, I will identify and quantify the relationship between forces and adhesion strength in mutants affecting either integrin-ECM binding or muscle contractility by utilizing in vivo laser ablation and magnetic tweezers. Second, I will examine whether and how IPP complex -a core module of the integrin adhesome- alters the molecular forces transmitted across Talin, which is a major mechanosensor at integrin junctions, utilizing suitable FRET-based biosensors. Collectively, this interdisciplinary research will provide a novel mechanical framework of how cells integrate forces and maintain tissue integrity in the living organism. Given the striking similarities in the molecular organisation of the myotendinous junctions between fly and human, the outcome of this work will provide a deeper understanding of how we can better combat dystrophic diseases.";153085,44;153085,44;H2020-MSCA-IF-2018;/MSCA-IF-EF-ST;IDRYMA IATROVIOLOGIKON EREUNON AKADEMIAS ATHINON;EL;;;;1;0;0;1;0;0 221742;835876;SICILYWAR;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Culture Heritage in Danger: Archaeology and Communities in Sicily during the Second World War (1940–45);2019-11-01;2021-10-31;;"This multidisciplinary, innovative project investigates antiquities in the Second World War context in Sicily (1940–45). The island’s cultural and archaeological heritage was under major threat from Allied bombing, landing and military occupation. The project pursues to reconstruct contexts and social networks involving the national and military authorities, archaeologists and local communities, acting and ‘clashing’ in a state of war and emergency. In particular, our research aims: a) to investigate how national, local civilian and military authorities dealt with the discoveries of archaeological finds in the area from construction of military structures by the Regio Esercito Italiano and Allied forces to the protection of antiquities; b) to reveal how the war impacted on the cities and their populations and to reconstruct contexts and social networks involving the national and military authorities, archaeologists and local communities, acting and ‘clashing’ in a state of war and emergency; c) to contextualise Sicilian archaeology in the wider European stage, comparing Sicily with other European contexts, where advancing war operations imposed exceptional measures to protect culture heritage (e.g. Belgium, France, UK, etc.). In terms of methodology, all archival and archaeological data will be assessed to obtain a full historical reconstruction of events, conveyed into a GIS and published through a book and two papers. Targeted surveys would be also beneficial to trace evidence and remains of bunkers and camps at some Sicilian sites. Our inquiry, which fully fits into the remarkable methodological pluralism of Ghent, is strongly interdisciplinary, because it embraces various subjects. They merge together in a fuller historical reconstruction and will therefore benefit historians, archaeologists, art historians and social studies experts, who are jointly interested in inspecting novel data on Sicilian antiquities, local communities and war contexts in the 1940s";166320;166320;H2020-MSCA-IF-2018;/MSCA-IF-EF-ST;UNIVERSITEIT GENT;BE;;;;1;0;0;1;0;0 221710;838596;COLIBRI;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Click chemistry Options for Live Immuno Brain Imaging;2019-10-01;2021-09-30;;As the world’s population is living longer, age-related neurodegenerative diseases (ND) such as Alzheimer’s and Parkinson’s are becoming a larger global issue. To date, no cure exists, and the European Union considers the understanding and the diagnosis of ND as key research areas. In this context, the overall aim of the fellowship is the development of a versatile method for immuno based brain PET, as a general translational molecular research method that can also be applied for early diagnosis of ND and follow up of the efficacy of novel ND therapies. This will be realized through a pretargeting approach using in vivo click chemistry in brain. More specifically, I will investigate the usefulness of 18F-TCO (trans-cyclooctene derivatives) for pretargeted PET imaging of ?-synuclein for Parkinson’s disease. The project will be divided into 4 objectives: (1) Design and synthesis of fluorine-18 labelled TCO derivatives with optimal brain uptake and clearance (“18F-brainTCO”), (2) Evaluation of in vivo kinetics of a polar peripheral blocking TCO derivative, (3) Tetrazine derivatization of an antibody (TzAb) targeting ?-synuclein, investigation of in vitro and in vivo binding to ?-synuclein, and in vitro and in vivo availability for click reaction, (4) In vitro (autoradiography) and in vivo (microPET/MR) imaging of the TzAb binding to ?-synuclein using 18F-brainTCO. The success of COLIBRI will rest on its interdisciplinary since various scientific fields will be covered: organic synthesis, flow chemistry, antibody derivatization, radiochemistry, in vitro/ex vivo tests, in vivo tests in animal models and PET imaging. The project also includes work packages dedicated to the project management (personal career development plan, progress monitoring, budget, ethics and risk management), training (techniques, courses, supervision of students), and dissemination and communication (publications, reports, lab meetings, conferences, popularization events, Internet presence, ...).;166320;166320;H2020-MSCA-IF-2018;/MSCA-IF-EF-RI;KATHOLIEKE UNIVERSITEIT LEUVEN;BE;;;;1;0;0;1;0;0 221503;844895;Amazonart;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Conquering Self-Representation: A Collaborative Approach to the Aesthetical-Political Dimension of Amazonian Contemporary Art;2019-09-01;2021-08-31;;This project develops a novel theoretical and methodological approach to understand the work, trajectories and activism of indigenous Amazonian contemporary artists as they enter global art circuits and seeks to produce more suitable curatorial narratives. Over the last decade the field of contemporary art has expanded its boundaries through the integration of art practices from various parts of the globe including indigenous art. A significant scholarship has traced the practices and global articulations of Australian and North American indigenous artists, which have developed a strong circuit of art agents and stimulated readjustments in art historical narratives. Yet the global rise of other vibrant indigenous art practices requires immediate attention. This is the case of Amazonian contemporary art which is mobilising different aesthetics and agendas and proposing novel contributions to the arts and humanities at large. With a focus on Amazonian Peruvian artists, this project develops a novel approach to explore the work, trajectories and activism of indigenous Amazonian contemporary artists as they enter global art circuits. Its aim is to produce the first major study on Amazonian contemporary art that expands the current framework of analysis of art and shamanism to look at artists’ practices, agendas and mobility across the local, urban, national and global arenas and to propose more suitable vocabularies and curatorial narratives. It does this through an innovative collaborative methodology with Amazonian artists responding to their aim of self-representation. This MSCA action draws on my on-going collaborations with Amazonian artists and on my background in the fields of anthropology, museum studies and cultural policies. The participatory and interdisciplinary approach of this research seeks to contribute to dialogues amongst anthropology, art history and curatorial studies and benefit museum practices and policies in addressing indigenous art today.;224933,76;224933,76;H2020-MSCA-IF-2018;/MSCA-IF-EF-CAR;UNIVERSITY OF ESSEX;UK;;;;1;0;0;1;0;0 221573;846476;ESX-4 T7SS;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Structure/function of a prototypic type VII secretion system from a fast-growing pathogenic mycobacteria;2019-04-01;2021-03-31;;Mycobacterium abscessus (Mab) is an opportunistic-multidrug-resistant non-tuberculous mycobacteria responsible for multiple clinically-acquired infections both pulmonary and extrapulmonary. Unlike many rapidly growing mycobacteria (RGM), Mab is able to survive and multiply within macrophages, similar to slow growing mycobacteria (SGM) such as M. tuberculosis (Mtb). In Mtb, five T7SS (ESX-1-5) have been identified and shown to be essential for intracellular survival (ESX-1), virulence (ESX-1 and ESX-5) or growth (ESX-3). T7SS are composed of five protein components essential for function: EccB, EccC, EccD, EccE and MycP. Except for a low-resolution structure of the holo ESX-5 complex from the host lab at 13 ? resolution, no structural data on any T7SS have been published to date, rendering structural work timely and eagerly awaited by relevant communities. Deemed inactive due to its lack of one of the established T7SS components EccE4, ESX-4 has been considered an ancestral T7SS form. However, Mab possess a fully intact and functional ESX-4, essential for its intracellular survival, rendering it a highly attractive target for an in-depth characterization. Here, I propose an interdisciplinary project that includes both functional and structural investigation. As the 2 M Dalton-holo-complex crosses the Mab inner membrane, experimental structural work will be challenging and require an integrative modeling approach to combine diverse experimental data sets. Complementary infection biology experiments including microbiology, genetics and cell biology will be carried out by collaborators. With this work, I aim to respond to central questions related to T7SS in general and Mab ESX-4 specifically, such as: what is the mechanism of T7SS-mediated secretion? What makes ESX-4 specific and different from other T7SS? What is the specific role of EccE4 to establish a functionally active ESX4? and What are the substrates and specific mechanism of ESX-4 substrate recognition?;162806,4;162806,4;H2020-MSCA-IF-2018;/MSCA-IF-EF-ST;EUROPEAN MOLECULAR BIOLOGY LABORATORY;DE;;;;1;0;0;1;0;0 221529;838593;CNSOL;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Carbon Nanomembranes with Sub-Nanometer Channels for Molecular Separation in Organic Liquids;2019-08-01;2021-07-31;;"Energy efficiency is a key principle of the EU’s 2020 strategy for smart, sustainable and inclusive growth, and implementation of this strategy requires innovation in energy intensive industries. Organic solvent nanofiltration (OSN) meets this need—it is a membrane-based separation with the potential to achieve more than 90% energy savings over conventional distillation in the energy intensive chemical industry. Current challenges for OSN are the need for materials with high flux, high selectivity and high chemical resistance. This proposal advocates meeting this need by constructing a membrane with: i) an ultrathin selective layer, ii) uniform pore sizes and iii) a cross-linked network. Carbon nanomembranes (CNMs) are 2D materials made by crosslinking of self-assembled monolayers; this results in a film with single-molecule thickness. CNMs mainly comprise carbon, resulting in chemically-stable separating layers. Also, their molecular structure is tunable by synthesis with purpose-designed molecules. Recently, the Fellow was part of the team which created the first 1.2-nm thin CNM with a high density of sub-nm channels, providing ultrafast permeation of water while blocking the passage of most other molecules. This project will combine the Fellow’s expertise in the development of single-molecule-thick films with the host’s expertise in OSN and interfacial synthesis; it aims to design new nanomaterials for advancing molecular separation in organic liquids. The objectives of the project are to: 1) demonstrate the ability of freestanding CNMs for OSN; 2) explore the tunability of CNMs at a molecular level for improved selectivity; 3) create nanocomposite membranes comprising interfacially synthesized mesoporous films supporting CNM separating layers. This highly innovative and interdisciplinary research will promote the Fellow’s career prospects by widening her research perspectives, enriching her research experiences and expanding her network with European colleagues.";224933,76;224933,76;H2020-MSCA-IF-2018;/MSCA-IF-EF-ST;IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE;UK;;;;1;0;0;1;0;0 221640;845976;GuideArtifEvol;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Tracking and guiding artificial enzyme evolution via landscape inference;2019-07-01;2021-06-30;;"Directed evolution is an effective method for protein engineering. The host laboratory is designing innovative techniques for the directed evolution experiments of enzymes, with the possibility to test millions or billions of variants to be tested at each cycle. In this project, I will introduce the use of full-gene next generation sequencing to supervise the exploration of variants at the sequence level and quantitatively characterize the fitness landscape, with a focus on non-additive effects of mutations into fitness (epistasis). Furthermore, this information will be included in DE protocols to guide a more efficient exploration of the sequence space. The project is a strongly interdisciplinary project consisting of experimental synthetic biology, physics modelling and bioinformatics analysis. It is focused in the study of DNA processing enzymes such as polymerase and endonucleases. The proposal includes the development of specific tools which should have an immediate impact on the scientific community: i. extend the applications of next generation sequencers to characterize full length genetic libraries of protein variants ; ii. adapt quantitative methods, previously developed for sets of structurally homologous proteins and derived from Potts model to study the catalytic properties of during directed evolution. iii. develop a new experimental protocol to control the number of mutations in libraries. The analysis will provide a better understanding of the topology of the fitness landscape of an enzyme, and its distortions under selective pressures, thereby clarifying the relations between sequence,function and evolution in proteins.";196707,84;196707,84;H2020-MSCA-IF-2018;/MSCA-IF-EF-ST;ECOLE SUPERIEURE DE PHYSIQUE ET DECHIMIE INDUSTRIELLES DE LA VILLE DEPARIS;FR;;;;1;0;0;1;0;0 221501;839585;IMaP;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Imaging tumor vessels as a marker for p53 mutation status in cancer;2020-08-01;2022-07-31;;"The p53 protein is mutated in over 50% of cancers. Because its expression often promotes tumor growth and is associated with resistance to treatment, there has been great interest in treating cancers based on p53 mutation status. However, the use of p53- targeted therapies requires knowing the mutation status. DNA sequencing is one approach, but requires invasive biopsies, and newer sequencing techniques still face technical hurdles. Non-invasive imaging techniques offer an alternative approach for detecting mutation status. Given that p53 regulates blood vessel growth, and that vessel imaging is used clinically to monitor response to cancer therapy, I hypothesize that tumor vessels could be used as an imaging marker to identify p53 mutation status. To test this hypothesis, I will measure relationships between p53 mutations and vessel structure/function using my expertise in 3D cell biology, vessel imaging, and image analysis and the unique expertise of the host lab in p53 biology, proteomics, and flow cytometry. The objectives of this interdisciplinary work are: 1) to screen the effect of p53 mutants on vessel structure in vitro; 2) to characterize the molecular response of endothelial cells to p53-targeted therapies; and 3) to image the structure and function of vessels in mutant p53 tumors in vivo. If a relationship is found between p53 mutation status and tumor vessel features, then it could lead to the development of the first imaging marker of p53 mutation status. This marker could help clinicians select p53-directed therapies to personalize therapy for each cancer patient. Apart from scientific impact, the proposed work will also expand my career prospects and scientific network in Europe. Under the mentorship of the host lab supervisor Prof. Sir David Lane, who discovered p53, I will receive focused training to strengthen and diversify the scientific and transferable skills I need to transition from postdoctoral scientist to junior group leader.";203852,16;203852,16;H2020-MSCA-IF-2018;/MSCA-IF-EF-ST;KAROLINSKA INSTITUTET;SE;;;;1;0;0;1;0;0 209956;742145;B-PhosphoChem;SIGNED;H2020-EU.1.1.;ERC-2016-ADG;H2020;Exploration of the 2D-Chemistry of Black Phosphorous;2017-08-01;2022-07-31;;We propose the development of the chemistry of black phosphorus (BP). B-PhosphoChem will constitute a new text book chapter in the realm of synthetic chemistry located at the interface of inorganic-, organic-, and materials chemistry as well as solid state physics. B-PhosphoChem will provide the basis for exciting and so far elusive applications such as ion batteries and stable high performance devices. Thin sheets of BP represent a new class of 2D materials and have recently raised tremendous interest in the scientific community. Outstanding physical properties such as high charge carrier mobility, combined with transparency and the persistence of a band gap have been discovered. However, the chemistry of BP remains still unexplored. B-PhosphoChem will close this gap and will a) provide the opportunity to modulate and fine tune the physical properties, b) allow for considerably improving the processability and increasing the solubility, c) establish concepts for the desired chemical stabilization, d) give access to the combination of BP properties with those of other compound classes, e) reveal the fundamental chemical properties and reactivity principles, and f) provide methods for establishing practical applications. Five work packages will be addressed: 1) Production of Thin Layer BP, 2) Supramolecular Chemistry of BP, 3) Intercalation Compounds of BP, 4) Covalent Chemistry of BP, and 5) BP-Based Materials and Devices. The work packages will be supported by systematic calculations. For our group, whose core competence is synthetic organic and supramolecular chemistry, the orientation towards inorganic phosphorus chemistry constitutes a major step into a completely new direction. However, we are convinced to be the most predestinated research group in the world successfully facing this challenge because of our leadership and well documented interdisciplinary experience in synthesizing and characterizing 0D-, 1D-, and 2D nanostructures.;2491250;2491250;ERC-2016-ADG;/ERC-ADG;FRIEDRICH-ALEXANDER-UNIVERSITAET ERLANGEN NUERNBERG;DE;;;;1;0;0;1;0;0 199838;687662;SPEXOR;SIGNED;H2020-EU.2.1.1.;ICT-24-2015;H2020;Spinal Exoskeletal Robot for Low Back Pain Prevention and Vocational Reintegration;2016-01-01;2019-12-31;;"Low-back pain is the leading cause of worker absenteeism after the common cold, accounting for 15% of sick leaves and hundreds of millions of lost work days annually [Walking 2.0, Nature, 2015]. Most of today's robotic assistive devices are in forms of exoskeletons that augment the motion of legs and arms and neglect the role of spinal column in transferring load from the upper body and arms to the legs. In SPEXOR we will fill this gap and design a novel and revolutionary spinal exoskeleton to prevent low-back pain in able bodied workers and to support workers with low-back pain in vocational rehabilitation. The concept to realize the objectives of SPEXOR is driven by several interdisciplinary ideas that push current understanding of low-back pain intervention through several innovative research and technological stages. First, robot-centred requirements for low-back pain prevention are determined and a musculoskeletal stress monitoring system is developed to unobtrusively measure the associated key variables. Then, optimal design parameters and sensorimotor strategies are provided with respect to the robot-centred requirements and their associated key variables. Based on these aspects, a spinal exoskeleton mechanism and its actuation is developed and adaptive control architecture is employed. Such research and development cycle is enclosed by multi-phase end-user evaluation, usability and satisfaction studies. The project builds upon the partner's extensive experience with work ergonomics, modelling and optimization of human movement, design, control and evaluation of exoskeletons. Several beyond-the-state-of-art scientific approaches and technologies will be employed through a colourful mixture of research, industrial, SME and end-user partners of the consortium. Ultimately, the results of SPEXOR will have a significant impact well beyond the current scientific understanding and technological capabilities of assistive robots used in daily life and health care.";3989025;3989025;H2020-ICT-2015;/RIA;INSTITUT JOZEF STEFAN;SI;"STICHTING VU;VRIJE UNIVERSITEIT BRUSSEL;OTTO BOCK HEALTHCARE PRODUCTS GMBH;RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG;S2P DOO;OTTOBOCK SE & CO. KGAA;STICHTING HELIOMARE";"NL;BE;AT;DE;SI";;1;0;0;1;0;0 221747;837491;SyLeNCe;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Synapses between Leukaemia and its Neighbouring Cells;2020-07-01;2022-06-30;;Our understanding of the different layers of organization in tissues remains limited. Stem cell niches offer a tightly controlled environment and a unique opportunity to look into this question. Reductionist approaches have been proven highly efficient dissecting the complexity of stem cell niches in a unidirectional fashion. However, this approach fails to recognize the tri-dimensional complexity of tissue organization. Hence we propose a systems biology approach based on low input and single cell RNA sequencing of bone marrow niche populations in order to establish not only the molecular landscape of cells that comprise the stem cell niche in homeostasis and disease but also the lineage relationships that may exist between cells in the stroma. Using the mouse bone marrow niche during neoplastic transformation to acute myeloid leukemia (AML), we will first unravel the cellular and molecular interactions that constitute the tumor microenvironment during disease development and progression using multi parametric flow cytometry and RNA-sequencing. Information gathered from these experiments will also provide a list of molecular candidates for therapeutic intervention in AML. We will validate those candidate cell populations and genetic pathways by means of gain and loss-of-function assays in vitro and in vivo using murine models and primary human AML samples. Completion of our interdisciplinary project will provide, for the first time a complete transcriptional and cellular map of a tissue, revealing the heterotypic interactions that define the real nature of a tissue. Perhaps then we could start to appreciate the elegant complexity of the ecosystem that the stem cell and its niche share. I hope SyLeNCe will facilitate the description of novel vulnerabilities that could be explored therapeutically for the treatment of acute myeloid leukaemia having an impact on the quality of life and long-term survival of AML patients.;160932,48;160932,48;H2020-MSCA-IF-2018;/MSCA-IF-EF-RI;FUNDACION PARA LA INVESTIGACION MEDICA APLICADA FIMA;ES;;;;1;0;0;1;0;0 221576;847596;LIMES;SIGNED;H2020-EU.1.3.4.;MSCA-COFUND-2018;H2020;The Hardening and Softening of Borders: Challenges for Europe and the World;2019-12-01;2024-11-30;;"LIMES is a doctoral programme for 13 talented PhD candidates in the domain of the humanities and social sciences, centred on the theme of ‘The Hardening and Softening of Borders: Europe in a Globalising World’. The dynamics of ‘softening’ and ‘hardening’ borders have become key issues in social and political transformations. Conducting research within this framework means working on the frontline of societal and scientific innovation, and is therefore particularly attractive for a new generation of interdisciplinary researchers. Moreover, Maastricht – located in the heart of the transnational Meuse- Rhine Euroregion – offers excellent opportunities to function as springboard for the mobility of ESRs. The programme ensures that its graduates are well-equipped for the job market, within and outside academia. A rich training programme and tailor-made secondments at one of the external partners are geared towards extending the employability of LIMES graduates far beyond traditional options.";2820480;1410240;H2020-MSCA-COFUND-2018;/MSCA-COFUND-DP;UNIVERSITEIT MAASTRICHT;NL;;;;1;0;0;1;0;0 221752;845014;BIONA4ART;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;BIO-inspired NAcre-like materials FOR the next generation of conservation treatments in stone ART works;2019-06-01;2022-05-31;;"The degradation of our rich stone cultural heritage (CH) represents an irreversible loss; an issue that has become urgent due to the increase of natural decay caused by climate change and the impact of atmospheric pollution and/or the current use of inappropriate treatments against stone weathering. The main challenge of BIONA4ART project will be to address this issue within an innovative framework in the conservation science: i) the development of a new generation of bioinspired nacre-like composites with self- healing and antimicrobial properties; and ii) its validation as stone conservation treatments with the aid of advanced characterization techniques. Thereby this research is marked by an interdisciplinary approach involving material science, biomaterials, physics, chemistry, petrophysics and CH conservation. In order to develop the proposed research the applicant will acquire new research skills by partnering her with the three specialized institutions involved: the Spanish National Research Council (CSIC) (supervisor Prof. R. Fort, world-renowned expert in the stone CH conservation), the Johns Hopkins University (JHU) (supervisor: Prof. H. Fairbrother, expert in nanocomposites, environmental implications and applications of nanomaterials), and the Max Planck Institute for Polymer Research (MPI-P), (supervisor Dr. S. Weber, internationally recognized expert in the use and development of SFM methods to study the underlying physics of nanoscale systems). The new knowledge and transferable skills gained during the project coupled with the opening of an innovative and exciting research line in the stone-CH field, will be an ideal springboard for the applicant´s subsequent career, which is to become a fully independent academic researcher in a top european university.";245732,16;245732,16;H2020-MSCA-IF-2018;/MSCA-IF-GF;AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS;ES;;;;1;0;0;1;0;0 221725;840271;Laminar-PL;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Ultra-high field imaging of perceptual learning and human brain plasticity;2019-04-01;2021-03-31;;Learning and experience shape key cognitive functions of the adult human brain and support our ability to interact in complex and dynamic environments. Yet, the brain mechanisms that support our ability to learn from cluttered and inherently ambiguous sensory information and improve our perceptual decisions with training remain largely unknown. My proposal aims to investigate: (i) the neural basis of perceptual learning in the human visual cortex (ii) the neural computations that underlie perceptual learning and (iii) the brain connectivity (i.e. how different brain areas work together) that supports behavioural improvement due to training. To achieve this, I will combine behavioural paradigms measuring perceptual learning, ultra high-field 7T imaging of brain activations at the finer scale of laminar layers (i.e. across cortical depth) and state-of-the-art computational modelling. This integrated multidisciplinary approach will contribute significantly to our knowledge of how the brain optimises its capacity for adaptive behaviour through learning and experience. Further the proposed work has potential practical implications for the design of education and rehabilitation training programmes in life-long development and disease. Finally, this interdisciplinary research experience boosted by collaborations with industrial partners will benefit greatly my career development to an independent researcher in the field of computational cognitive neuroscience.;212933,76;212933,76;H2020-MSCA-IF-2018;/MSCA-IF-EF-ST;THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;UK;;;;1;0;0;1;0;0 221618;820444;ENERGY-X;SIGNED;H2020-EU.1.2.3.;FETFLAG-01-2018;H2020;ENERGY-X: Transformative chemistry for a sustainable energy future;2019-03-01;2020-02-29;;"The rationale of Energy-X is to develop the science as well as technology enabling a sustainable production of synthetic fuels for energy storage and as feedstock for the chemical and materials industry. Energy-X brings together interdisciplinary academic research (chemistry, physics, engineering and economic science) with cross-industrial technological expertise (chemical, engineering, utilities, mobility, agriculture) to provide a platform for future chemical energy conversion technology in Europe. Energy-X will contribute disruptive new science and technology enabling efficient conversion of solar and wind energy into chemical form and will combine this ambition with scale-up to industrially relevant conditions by integrating with European industry. Energy-X will also transfer the knowledge into two demonstration projects: manufacturing of carbon-neutral aviation fuels and decentralized production of fertilizers with no CO2 footprint.";976115;976115;H2020-FETFLAG-2018-01;/CSA;DANMARKS TEKNISKE UNIVERSITET;DK;"DECHEMA GESELLSCHAFT FUER CHEMISCHE TECHNIK UND BIOTECHNOLOGIE E.V.;UNIVERSITEIT GENT;COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES;ALLIANCE EUROPEENNE DE RECHERCHE DANS LE DOMAINE DE L'ENERGIE;RWI - LEIBNIZ-INSTITUT FUR WIRTSCHAFTSFORSCHUNG;EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH;European Research Institute of Catalysis A.I.S.B.L.;UNIVERSITAT POLITECNICA DE VALENCIA;INSTYTUT KATALIZY I FIZYKOCHEMII POWIERZCHNI IM. JERZEGO HABERA POLSKA AKADEMIA NAUK;UNIVERSITEIT UTRECHT;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;USTAV FYZIKALNI CHEMIE J. HEYROVSKEHO AV CR, v. v. i.";"DE;BE;FR;CH;ES;PL;NL;CZ";;1;0;0;1;0;0 221665;843455;MTrill;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Machine Translation Impact on Language Learning;2019-04-25;2021-04-24;;The MTrill is a process-oriented research that aims at investigating how online freely available Machine Translation (MT) systems are impacting the acquisition and processing of English as a second language. The research will shed light on issues involving a central aspect of language acquisition: the so-called language binding, i.e., the ability to combine single words properly in a grammatical sentence in a second language. To pursue this goal, a syntactic priming experiment will be carried out in which participants will be tested as whether they produce the same syntactic structures that had been previously seen during a translation task using a MT. The project brings a brand-new methodological approach within MT process-oriented evaluation research and it goes beyond the existing state-of-the-art approaches since it will focus on translation processing complemented by product analysis (oral production). The project will be conducted under the supervision of Professor Andy Way and Doctor Monica Ward in the ADAPT Centre based in Dublin City university. A four-months secondment will be carried out in the Max Planck Institute of Psycholinguistics (MPI) in Nijmegen, The Netherlands, in the Neurobiology of Language research group under the supervision of Professor Peter Hagoort. The knowledge acquired during the secondment will be consolidated in the return phase through implementation of the experiments carried out for this project as well as through teaching and co-supervision activities. Results of this research will be disseminated through conferences and journal paper publications and will be communicated to multiple audiences through articles published in non-academic magazines, blogs and social media. The fellowship will attract academic networking opportunities, skill-set improvements and a personal and professional transformative experience to the researcher since it will establish her as the new leading light in research of an interdisciplinary field.;184590,72;184590,72;H2020-MSCA-IF-2018;/MSCA-IF-EF-ST;DUBLIN CITY UNIVERSITY;IE;;;;1;0;0;1;0;0 221680;839402;PLASMIONICO;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Plasmon-resonance driven thermionic emitters for improved solar energy harvesting;2019-04-01;2021-03-31;;'PLASMIONICO is an innovative proposal aiming at advancing sustainable energy production by developing a 'cold-cathode' thermionic generator as key component of novel photovoltaic/thermoelectric (PV/TE) hybrid devices to outperform the solar cell and thermoelectric generator working separately. The cold cathode, instead of being brought to extremely high temperatures, produces the emission of electrons by the absorption of infrared (IR) photons in the unused region of the solar spectrum below the PV cell bandgap. The IR photons will launch plasmons at a nanostructured metallic cathode, which upon relaxation will generate a photocurrent. A great advantage is that plasmon-resonance driven thermionic emission is not restricted to a particular class of materials, working for Si-based devices as well as for organic (soft and flexible) materials, since the cathode temperature is that of a working solar cell. Research activities will span the whole added-value chain from fundamental studies of materials for thermionic generation, including the optimization of plasmonic nanostructures, reaching higher TRLs by realization of a thermionic demonstrator. PLASMIONICO would contribute to the current energy challenge, a priority in both the EU and ICMAB-CSIC research agendas. The proposal possesses high interdisciplinary character by merging activities in physics, chemistry, materials science and device technology, which together with the unique network of international partners will contribute to boost the track records and develop the career of the applicant.';172932,48;172932,48;H2020-MSCA-IF-2018;/MSCA-IF-EF-ST;AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS;ES;;;;1;0;0;1;0;0 221513;842881;PONS;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Fabrication of Polysaccharides-Protein complex Nano-Hybrid Scaffold as regenerative biomaterial for bone tissue engineering;2019-04-01;2021-03-31;;The development of new biomaterials in bone tissue engineering requires an interdisciplinary joint-venture combining material and biomedical sciences. The aim of the regenerative biomaterial is to repair the functional defect or damages by generation of a bone substitute. The biomaterial has to be highly engineered at the molecular level to mimic the function of the extracellular matrix including complex cell-material interactions and physical properties of the scaffold. The focus of this proposal is to fabricate an organic-inorganic complex nanohybrid scaffold as a bone implant for applications in tissue engineering. The nanohybrid scaffold is based on three components: an inorganic particle containing biological carrier molecules (BCM), polysaccharide (cellulose) and protein (collagen). Layered-double hydroxides (LDH) inorganic particles will be functionalized with BCM allowing controlled release of biological molecules that will direct cell-material interactions. Polysaccharides (Pol)–Protein (Pro) biomaterials reinforced with LDH-BCM will be fabricated and tested in ectopic bone formation analysis technology which will translate to clinical trials. In essence, Pol-PrO complex reinforced LDH-BCM Nanohybrid Scaffold (PONS) will be developed as regenerative biomaterial in bone tissue engineering and will incorporate cutting edge stem cell technologies, engineering of advanced materials and controlled delivery of biomolecules in vitro and in vivo.;178320;178320;H2020-MSCA-IF-2018;/MSCA-IF-EF-ST;KATHOLIEKE UNIVERSITEIT LEUVEN;BE;;;;1;0;0;1;0;0 221689;845268;MSOPGDM;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Mechanistic studies of prokaryotic genome defense mechanisms;2019-04-01;2021-03-31;;The constant biological arms race between prokaryotic organisms and invading mobile genetic elements has resulted in the evolution of sophisticated genome defense mechanisms. The genes encoding for immunity commonly reside in genomic clusters known as defense islands that are in the vicinity of other host-defense loci. Recent studies of defense islands have uncovered ten novel host defense mechanisms whose molecular mechanisms remain elusive at present. The proposed project aims to provide a mechanistic basis for genetic immunity in two novel host defense systems: Druantia and Shedu. These systems contain genes encoding nucleases, ATPases and helicases, which strongly suggests that they provide immunity by directly targeting invading nucleic acids. To unravel the molecular mechanisms that underpin immunity in these systems, I will apply a highly interdisciplinary approach by using biochemical and state-of-the-art structural biology techniques, including high-throughput X-ray crystallography, cryo-EM and crosslink-coupled mass spectrometry. Understanding these mechanisms will provide fundamentally new insights into prokaryotic biology and the evolution of host-virus defense systems. Furthermore, these studies might uncover novel molecular activities that may be exploited for use as genetic engineering tools.;191149,44;191149,44;H2020-MSCA-IF-2018;/MSCA-IF-EF-ST;UNIVERSITAT ZURICH;CH;;;;1;0;0;1;0;0 221677;838937;PoliticalPrisoners;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Political prisoners: a transnational question in 19th century Italy;2019-09-01;2022-08-31;;"This research project is a transnational historical investigation which examines the international role and representations of Italian political prisoners during the 19th century. Its goal is to investigate how and to what extent political prisoners were key figures not only in the construction of an Italian nationalist discourse, but equally in the foreign understanding of and commitment for the Italian Risorgimento. Moreover it will delineate how humanitarian debates operated in the commitment towards a national political cause. The project will place political detainees beyond legal and political history, and insert them in the context of the new questions raised by transnational and cultural history, and by the history of humanitarianism. I argue that political prisoners acted as political and patriotic agents at home as well as abroad. Not only did the experience of imprisonment influence the detainees’ political activities and identities, and help to create a sense of national community; but it influenced the representation of the Italian national movement abroad. The project will offer a new approach in studying political imprisonment emphasising its international and humanitarian dimension and will challenge the current state-of-the-art, highlighting how political prisoners were an international concern already in the 19th century. Finally the research will help to understand the historical evolution of a European sensitivity and a commitment towards political detainees, refugees and people persecuted for political opinions and the evolution of international protection and humanitarian discourses. There is a running thread between these historical issues and questions concerning political prisoners in the world today and the international awareness and concern about them. The research project is a multi-lingual and multi-archival study that will employ an interdisciplinary and a transnational approach.";251002,56;251002,56;H2020-MSCA-IF-2018;/MSCA-IF-GF;UNIVERSITA CA' FOSCARI VENEZIA;IT;;;;1;0;0;1;0;0 221726;835758;REL-NET;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Entangled Interfaith Identities and Relations from the Mediterranean to the United States: The St James Association and Its Transnational Christian-Jewish Network in the Israeli-Palestinian Conflict;2019-11-05;2022-11-04;;Mixed religious identities and interfaith relations represent one of the most crucial and debated phenomena in the 21st century. The revival of the religious dimension in the world is evident in the growing religious implications in modern and contemporary wars. The REL-NET project tackles these global issues through the analysis of a significant case study that has been overlooked in the historiography: the history of Christian–Jewish transnational networks between Israel, Palestine, the Middle East, Europe and the United States after the establishment of the State of Israel in 1948. In particular, I will focus on the history of the St James Association (SJA) since the end of the 1940s. The SJA is a community formed by Holocaust survivors who converted to Christianity, moved to Israel and settled in the mainly Arab Jerusalem Church. Some SJA members became well-known intellectuals who developed an international network that influenced Christian–Jewish–Muslim relations during the Israeli–Palestinian conflict and on a global scale. Using multiple and interdisciplinary methodologies and an unprecedented mass of unpublished archival documentation disseminated all over the world will lead me to retrace the strands that contributed to the new relations between Jews and Christians while also engaging Muslim communities. Involving an extensive programme of teaching, language, digital and project management training at Fordham and Ca’ Foscari universities and under the supervision of two leading scholars in these fields, the MSCA-GF will give me the extraordinary opportunity to outline a new framework for the historical appraisal of religious relationships in the contemporary world, delivering innovative outputs in terms of academic products and in disseminating them to a larger and non-specialist audience and significantly advancing my already solid experience within European research programmes (ERC and ERASMUS), which will decisively enhance my academic career.;269002,56;269002,56;H2020-MSCA-IF-2018;/MSCA-IF-GF;UNIVERSITA CA' FOSCARI VENEZIA;IT;;;;1;0;0;1;0;0 221761;841844;FR and ENG Petrarch;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Translational Traditions and Imaginaries: A Comparative History of Petrarch’s Canzoniere in French and English;2020-09-01;2023-08-31;;The main objective of the project is to offer a comparative study of early modern translations of Petrarch’s Canzoniere in English and French, as well as examining their impact on their respective ‘translation traditions’. First, I aim to clarify the features of European Petrarchism by focussing on its translational origins in two of the most influential European languages and cultures of the time (besides Italian). My second goal is to establish, from a comparative perspective, the place of Petrarch’s Canzoniere in the ‘culture of translation’ of early modern British Isles and France, in other words, all the modes and conceptions of translation in these linguistic spaces. My third objective is to identify the impact of early modern ‘translational imaginaries’ of Petrarch’s Canzoniere (that is to say, conceptions and representations of Petrarchan poetry in translated texts) in subsequent centuries, thus tracing their ramifications in these two interlinked literary cultures. The University of Montreal (UdeM) is the ideal environment to achieve this ambitious outcome and to improve my skills in translations studies during the first two years of the Fellowship. My supervisor Prof. Marie-Alice Belle, and the research team directed by her, ‘Trajectories of Translation in Early Modern Britain, 1473-1660: Routes, Mediations, Networks’, will provide me with crucial expertise in the study of paratexual materials and cultural networks involved in translation exchanges between France and the British Isles. During the last year, Prof. Venturi, in collaboration with his interdisciplinary research group ‘Textual Traditions and Communities in Early Modern Europe’ at the University of Oslo (UiO), will bring his philological expertise to the project and, under his supervision, I will be able to explore other aspects of the European reception and interpretation of the Canzoniere, including the commentary traditions and circulations of editions with paratexts.;253110,72;253110,72;H2020-MSCA-IF-2018;/MSCA-IF-GF;UNIVERSITETET I OSLO;NO;;;;1;0;0;1;0;0 221751;840633;Domesticities;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Gender, Infrastructure and the Production of Domesticity in the (Post)Communist City;2019-10-01;2021-09-30;;This research proposes to investigate the relationship between gender, the (post)communist state and architecture in the passage from socialism to its aftermath in Bucharest, Romania. The project explores the manner in which housing infrastructure was employed as a political technology in the production of gendered subjectivities—that is, women’s embodied experience of the built environment—in the communist and post-communist periods. The fall of the communist regime in 1989 and the emergence of capitalist democracy served both to contest and reshape former boundaries between the private and the public realms. At the same time, housing infrastructure is the main inheritance of the communist system and constitutes, within a new socio-political condition permeated by Western images, the physical structure that must accommodate a new type of domesticity. The research defines domesticity as a changing set of attitudes and praxes that are specifically linked to the political intention embedded within the communist housing projects. The main research objective is to establish the significance of housing infrastructures built in Bucharest between 1955 -1984 in the regulation of the home, the family and women’s roles in the communist and post-communist periods. The research will achieve this objective by interrogating, on the one hand, the interaction between processes of regulating, designing, building, using and imagining socialist housing and, on the other hand, the actual lived experiences of women. The approach of this research project is interdisciplinary, employing ethnographic methods, archival research, and drawing on specific theoretical frameworks—from architecture, anthropology, and gender studies—for analysis and interpretation. The research will be a unique contribution to existing scholarship on the legacies of communism in states from Eastern Europe, by relating questions of gender to the constitution of domesticity through infrastructure.;212933,76;212933,76;H2020-MSCA-IF-2018;/MSCA-IF-EF-CAR;UNIVERSITY COLLEGE LONDON;UK;;;;1;0;0;1;0;0 221639;839310;CApaCITy;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;CAncer Stem Cell Imunoreceptors as potential Targets for skin Squamous cell carcinoma;2019-09-01;2021-08-31;;"Cancer stem cells (CSC) initiate, sustain the prevalence, and resistance to therapy of skin squamous cell carcinomas (SCC). It is well acknowledged that CSC self-renewal and clonal growth is governed by genetic mutations, but also by complex interactions between CSC and the microenvironment. Genetic therapy is difficult to achieve in clinical settings, therefore, targeting cells of the supportive tumor microenvironment is a promising advance to eradicate SCC. Using mouse models of SCC, our previous basic research results uncovered the existence of a direct crosstalk between skin CSC and tumor-associated macrophages (TAM) via Wnt signaling. Interestingly, we observed that Wnt regulated the expression of three CSC receptors, CD99, MFGE8 and Nectin-2, and governed the CSC-TAM crosstalk. Here, I propose to expand this basic research into a translational perspective, to explore the potential of CD99, MFGE8 and Nectin-2 as therapeutic targets for human SCC. There is a major interest in this arena, since the major caveat of targeting Wnt signaling in cancer is the lack of specificity to target CSC, without affecting somatic cells. Moreover, most clinical trials have not been fully efficient to dampen the Wnt response in tumors. Using a comprehensive and integrated approach based on human SCC, cell biology, omics and medical chemistry, along with powerful patient derived xerographs (PDX), my results must likely unearth a role for these immunoreceptors in governing the CSC-TAM crosstalk, and their potential as drug targets for human SSC. This interdisciplinary project will be conducted at the University of Copenhagen (UCPH) in Dr. Perez-Moreno, Dr. Merete Haedersdal, and Dr. Str?mgaard groups. Through the CApaCITy project, I will embark in a leading research area with several possibilities to grow into an independent international researcher.";207312;207312;H2020-MSCA-IF-2018;/MSCA-IF-EF-ST;KOBENHAVNS UNIVERSITET;DK;;;;1;0;0;1;0;0 215562;797777;NeuroVU;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;NeuroVU: Real-time Sensing in Microfluidic Models of the Neurovascular Unit;2018-06-27;2020-06-26;;"Disorders of the central nervous system are one of the grand health challenges of this century. Therapeutic development, however, remains limited by poor understanding of the brain, including of the neurovascular unit (NVU). The NVU acts as the gatekeeper between blood and brain for metabolites, disease agents, as well as drugs. Much research has relied on animals or simple cell models that recapitulate neither the cellular ensemble nor the environment of the NVU. Emerging Organ-on-Chip microsystems promise to overcome these limitations, but to date fall short on the relevance of cells used and the lack of continuous monitoring capabilities for chemical markers, metabolic conversions, and pharmacodynamics. My objective in this project is to develop the first NVU Organ-on-Chip integrating human-normal cells as well as biophysical and biochemical sensors for real-time monitoring, termed NeuroVU. I propose to rely on primary and induced pluripotent stem cells, which can achieve in-vivo-like properties, and off-stoichiometry thiol-ene-epoxies (OSTE\) as the enabling technologies. OSTE\ is a versatile polymer uniquely suited to supersede the prevalent polydimethylsiloxane/glass paradigm for the innovative system integration approaches needed here. I will first characterize and optimize it for compatibility with biological and sensor components. I will build on these component insights with microsystems integration to develop NeuroVUs featuring co-culture of NVU-normal cells, continuous monitoring of relevant ions & metabolites in addition to trans-endothelial electrical resistance, and tissue-like hydrogel structures. I will leverage collaborations with resident experts in materials and biology as well as my own strong background in microsystems integration to realize this highly interdisciplinary project. Ultimately, the NeuroVU will allow for unprecedented insights on NVU chemistry and has the potential to significantly accelerate pharmaceutical development.";185857,2;185857,2;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;KUNGLIGA TEKNISKA HOEGSKOLAN;SE;;;;1;0;0;1;0;0 213000;778045;e.THROUGH;SIGNED;H2020-EU.1.3.3.;MSCA-RISE-2017;H2020;Thinking rough towards sustainability;2018-01-01;2021-12-31;;"To tackle its critical raw material (CRM) dependency, Europe needs comprehensive strategies based on sustainable primary mining, recovery from secondary resources and recycling. The EC classified 20 CRMs due to their high economic importance and high risk of supply interruption. e.THROUGH has the ambitious vision of turning the challenge of CRMs dependence into a strategic strength for Europe, contributing towards declassifying some CRMs, as tungsten, indium, gallium and chromium, by: 1) Promoting new trends in the characterization and exploration of mineral deposits; 2) Mapping CRMs between EU mining regions; 3) Gaining knowledge on innovative processes for recovery secondary CRMs; 4) Redesign construction materials using secondary materials, closing loops, strongly supporting waste minimization; 5) Life Cycle Assessment (LCA) for the evaluation of global environmental impacts; 6) Transferring newly generated knowledge to stakeholders, both for policy development and standardization, and for shaping responsible behaviours. e.THROUGH is an intersectoral and interdisciplinary consortium of EU & Third Country partners of leading institutions that see waste as a resource to recover CRMs, influencing the whole value chain. By training human resources in CRMs´value chain, their recovery, recycling, further reuse and LCA, they become the much needed young and senior scientists and engineers for the growing EU CRM industry. The consortium comprises 40% industry and 60% research partners. This should help push Europe to the forefront in CRM sectors, providing eco-friendly alternatives in supply. The generated scientific relevant knowledge will be transferred to shape industries, communities and individual citizens’ behaviour, fostering corporate sustainability performance, important to influence economic agents’ choices. e.THROUGH will generate a win-win situation for both the environment and the economy, promoting the required transition towards a sustainable society.";733500;693000;H2020-MSCA-RISE-2017;/MSCA-RISE;NOVA ID FCT - ASSOCIACAO PARA A INOVACAO E DESENVOLVIMENTO DA FCT;PT;"LOMARTOV SL;ECO RECYCLING SOCIETA A RESPONSABILITA LIMITATA;AMPHOS 21 CONSULTING SL;DANMARKS TEKNISKE UNIVERSITET;E-MINES;UNIVERSIDAD DE MALAGA";"ES;IT;DK;FR";;1;0;0;1;0;0 209668;752979;MACROSS;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Multimedia Communication and Processing over Vehicular Cloud Networks for AutonomousDriving;2018-03-01;2020-02-29;;"Autonomous driving technologies have recently drawn enormous research attention. It is predicted that autonomous driving will become the most promising form of future Intelligent Transportation Systems (ITS) and will gradually gain market traction in the coming decade. Although several automobile manufacturers have recently demonstrated prototypes, a great number of technical challenges should be addressed in order to reap the full potential of autonomous driving. This project aims to pioneer a framework that leverages innovative multimedia communication and processing technologies for efficient sensor data exchange in order to support autonomous driving application over vehicular cloud networks (VCNs). The project is unique in its ground-breaking integration of two challenging technical aspects over VCNs: multimedia-driven vehicular wireless communications and network-aware adaptive multimedia processing. The interaction and mutual promotion between these two aspects will enable each to design more efficient operational procedure and protocols. The techniques to be developed will fill important gaps in the fundamental understanding of sensing data communication and processing technologies over VCNs, and will also provide the underpinning for system design and algorithm implementation for autonomous driving technologies. To accomplish the scientific objectives of the project, a series of research, training, and knowledge transfer activities will be carried out. The project will enable the fellow to broaden an interdisciplinary research background and greatly improve his career competence. It will lay the foundation for future long-term collaborations between the fellow and the hosting university, leading to greater social and industrial impacts and benefitting both EU and China.";195454,8;195454,8;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;THE UNIVERSITY OF EXETER;UK;;;;1;0;0;1;0;0 207037;734211;INTERACT;SIGNED;H2020-EU.1.3.3.;MSCA-RISE-2016;H2020;The INTERnAtional network on Crisis Translation;2017-04-01;2020-03-31;;"We propose to establish an interdisciplinary, intersectoral and international research and innovation network in Crisis Translation, called INTERACT. Crisis Translation is understood here as the translation of written information from one linguistic and cultural system to another in the context of a crisis scenario, with a view to enabling affected communities and responders to be prepared for crises, improve resilience and reduce the loss of lives. Due to the transboundary nature of modern day crises, crisis communication must be multilingual and multilingual crisis communication is enabled through translation. Multilingual information access through translation addresses work programme aims such as social fairness and democratic access to essential information for all. The primary focus of INTERACT is on health-related crisis content. The main objectives of the project are 1) to make meaningful and effective contributions to knowledge, policies, expertise, training and technology that enable accurate and timely translation-enabled crisis communication, with a particular focus on health-related content; 2) to improve outcomes for crisis-affected and at-risk communities by contributing to translation-enabled communication to, with and from those communities; 3) to enhance human skills, competences and cross-sectoral collaboration across academic, humanitarian, and industrial sectors involved in crisis translation. This will be achieved by focusing on five main topics: crisis communication policy, comprehension in limited proficiency communities, crisis machine translation, citizen translator education, and ethics and through collaboration across academic, SME, NGO, and Multinational partners. The contribution of INTERACT will be a much broader, better informed, innovative, much more impactful perspective on the challenges of crisis communication and the role of translation.";279000;229500;H2020-MSCA-RISE-2016;/MSCA-RISE;DUBLIN CITY UNIVERSITY;IE;"THE COCHRANE COLLABORATION;UNIVERSITY COLLEGE LONDON;UNBABEL, LDA";"UK;PT";;1;0;0;1;0;0 204929;705269;SCOUTFermi2D;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Strongly correlated ultracold fermions in two-dimensional tailored optical potentials: pairing, superfluidity and disorder;2016-08-22;2018-08-21;;"Two-dimensional fermionic systems exhibit some of the most remarkable phenomena in modern physics, combining fundamental aspects with a high technological impact. Their peculiar and rich behavior arises from the interplay between quantum statistics, dimensionality and strong interactions, which also makes their theoretical treatment extremely challenging. This project proposes to explore the physics of strongly correlated fermions in different two-dimensional (2D) landscapes with an ultracold gas of lithium atoms trapped in optical potentials. Ultracold quantum gases are in fact the ideal platform for approaching open problems in condensed matter theory and also an exciting toolbox for the search for novel synthetic phases of matter. The project aims to study fermionic superfluidity across the two-dimensional BEC-BCS crossover, unveiling its special nature by implementing advanced probing techniques such as high-resolution imaging and Bragg spectroscopy and suitable transport measurements that will reliably identify the transition to the superfluid regime. The investigation of first and second sound will be complemented by the study of the coherent Josephson tunneling between two weakly coupled 2D superfluids, a strong evidence of macroscopic phase coherence. By adding disorder, we propose to address the debated metal- and superconductor-to-insulator transitions in a pure controllable fashion, providing new insights into longstanding debates. Finally, we propose to realize three-components Fermi gases with controllable interactions, enhancing their stability in 2D. This will allow for approaching more exotic topics such as color superfluidity and trimer formation, linking our research to quantum-chromodynamics (QCD). An experimental machine has been already set up for the requirements imposed by these goals. The successful realization of the proposed experiments will shed new light on the intriguing and interdisciplinary field of 2D strongly correlated fermions.";168277,2;168277,2;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;CONSIGLIO NAZIONALE DELLE RICERCHE;IT;LABORATORIO EUROPEO DI SPETTROSCOPIE NON LINEARI;IT;;1;0;0;1;0;0 198154;636458;CogSoCoAGE;SIGNED;H2020-EU.1.1.;ERC-StG-2014;H2020;Tracking the cognitive basis of social communication across the life-span;2015-09-01;2020-08-31;;A vital part of successful everyday social interaction is the ability to infer information about others (e.g. their emotions, visual perspective, and language). Development of these social skills (termed Theory of Mind, ToM) has been linked to improvements in more general cognitive skills, called Executive Functions (EF). However, to date very little is known of how this link varies with advancing age, and no model exists to explain the relationship. Thus, the key aim of the proposed research is to systematically explore the cognitive basis of social communication and how this changes across the life-span. The research will address three complementary objectives: (1) to what degree can variations in ToM ability across the life-span be accounted for by changes in EF skills, (2) how do ToM ability and EF skill change over time in different age groups (using longitudinal methods, i.e. test-retest of the same participants), and (3) can ToM ability be enhanced through training specific EF skills, and how do these training effects differ across the life-span. Contrary to traditional studies of social communication, I will employ an interdisciplinary approach that links theory and practice from cognitive, social, developmental, and clinical (neuro)psychology to study the relationship between ToM and EF across a broad and dynamic age range (10 to 80\ yrs old). I will use cutting-edge combinations of techniques (eye-tracking and EEG) and paradigms, alongside sophisticated statistical methods to track the timecourse of social understanding, and model how it relates to EF and more general cognitive/social skills (eg. IQ, language) within and between individuals. This research will open up new horizons in ToM research by developing an intervention programme to enhance the quality of social communication in older adults (thus improving their mental health and well-being), which has the potential to be applied in other individuals with social communication deficits (eg. autism).;1488028;1488028;ERC-2014-STG;/ERC-STG;UNIVERSITY OF KENT;UK;;;;1;0;0;1;0;0 197133;665874;WaterSEED;SIGNED;H2020-EU.1.3.4.;MSCA-COFUND-2014-DP;H2020;Social, entrepreneurial and excelling doctors for water technology;2016-02-01;2021-01-31;;"The objective of the WaterSEED project is to provide a doctoral program to excellent early stage researchers (ESRs) that want to develop their skills and contribute to the development of breakthrough technologies for water related challenges. Key elements in the program are the strong focus on interdisciplinary interaction, entrepreneurial skills and societal relevance. The project will use the existing Wetsus doctoral (PhD) program as a strong base and will enable this program to become even more international and relevant for the European society. The Wetsus doctoral program has grown in the 10 years of its existence to a prime example of smart, regional specialization on water technology with a strong European connection between research institutes and industry partners. The research in the Wetsus program takes place in close collaboration with 90 companies that actively participate in the research through paying memberships to focused and high trust research themes. All Wetsus researchers have at least three contacts per year with these industry partners. The current doctoral program has a strong regional and national funding base. Through COFUND this program will be further expanded and strengthened by attracting 45 international, excellent young researchers to the program in the period of 2015-2020. It will also strengthen the European connection of the program by increasing the number of researchers from other countries than the host organisation to over 70%. The ESRs will be selected in two calls per year through a transparent and thorough selection process, including a two day WaterSEED Recruitment Challenge at Wetsus for the best candidates.";6670800;3335400;H2020-MSCA-COFUND-2014;/MSCA-COFUND-DP;STICHTING WETSUS, EUROPEAN CENTRE OF EXCELLENCE FOR SUSTAINABLE WATER TECHNOLOGY;NL;;;;1;0;0;1;0;0 205396;722176;INDEED;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2016;H2020;Innovative Nanowire DEvicE Design;2017-02-01;2021-01-31;;"Nanowires (NWs) exhibit unique properties that make them potential building blocks for a variety of next generation NanoElectronics devices. Recent advances have shown that NWs with predefined properties can be grown, offering a new paradigm enabling functional device prototypes including: biosensors, solar cells, transistors, quantum light sources and lasers. The critical mass of scientific knowledge gained now needs to be translated into NW technologies for industry. FP7-MC NanoEmbrace (ITN) and FUNPROB (IRSES), made substantial contributions to NW research, producing excellent scientific and technological results (>100 journal papers published) and delivered outstanding training in nanoscience and transferable skills to ESRs. Despite demonstrable scientific and technological advantages of NWs, NW-based technology concepts have not yet been translated into market-ready products, because industry and academia have not worked hand-in-hand to commercialize the research findings. Thus, it is essential that NW research is now directed towards customer-oriented scientific R&D; whilst applying innovative industrial design techniques to ensure rapid translation of the basic technologies into commercial devices. This ambitious challenge requires close collaboration between academia and the nascent NW industry, combining the efforts of scientists and engineers to address market needs. Building upon our previous achievements, a team of leading scientific experts from top institutions in Europe, strengthened by experts in innovative design and industrial partners with an excellent track record of converting cutting edge scientific ideas into market products has formed the INDEED network to address this challenge. To enhance employability, INDEED will train young ESRs to become experts with a unique skill set that includes interdisciplinary scientific techniques, industrial experience through R&D secondments and innovative design skills.";4000457,52;4000457,52;H2020-MSCA-ITN-2016;/MSCA-ITN-ETN;UNIVERSITY OF DURHAM;UK;"UNIVERSITY OF NEWCASTLE UPON TYNE;UNIVERSITE PARIS-SUD;KOBENHAVNS UNIVERSITET;ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE;INNOLUME GMBH;CONSIGLIO NAZIONALE DELLE RICERCHE;THE UNIVERSITY OF LIVERPOOL;IMINA TECHNOLOGIES SA;LUNDS UNIVERSITET;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;LAPPEENRANNAN-LAHDEN TEKNILLINEN YLIOPISTO LUT";"UK;FR;DK;CH;DE;IT;SE;FI";;1;0;0;1;0;0 198108;675526;REP-BIOTECH;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2015-EJD;H2020;European Joint Doctorate in Biology and Technology of Reproductive Health;2015-11-01;2019-10-31;;"The main objective of the European Doctorate in Biology and Technology of the Reproductive Health (REP-BIOTECH) is to build a research, training and academic programme in the interdisciplinary domain of reproductive health and fertility. Basic knowledge of mechanisms involved in mammalian fertilization and embryo development provides useful strategies to improve food quality (by implementation of efficient and secure animal reproductive technologies), human health (by contributing to the control of reproductive diseases and epidemiologic factors) and human and animal fertility (by identifying target molecules for successful conception or contraception). REP-BIOTECH is a PhD programme with the aim of training a new generation of creative, entrepreneurial and innovative Early-Stage Researchers (ESRs). ESRs must carry out independent research on a specific topic to be awarded a European Joint Degree from 5 European Universities (Beneficiaries). The PhD project will be jointly supervised within a joint governance structure in which the beneficiaries as well as the partner organisations will be actively involved. The Doctorate programme will expose ESRs to different sectors and they will acquire a comprehensive set of transferable skills working in the specific research area relating to their doctoral thesis. The consortium has a proven track record in their area and they have a history of fruitful scientific collaboration. Moreover, giving the diversity amongst the participating institutions, the ESRs will be able to face current and future challenges in order to convert knowledge and ideas into products and services for economic and social benefit. The strength of the partnership lies in being a multidisciplinary group (animal and human fertility, reproductive health and reproductive technologies) within the cooperation of 7 different European countries, the collaboration of Universities from Japan and United States and partners from the non academic sector.";3811469,04;3811469,04;H2020-MSCA-ITN-2015;/MSCA-ITN-EJD;UNIVERSIDAD DE MURCIA;ES;"UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN;UNIVERSITEIT GENT;UNIVERSITA DEGLI STUDI DI TERAMO;RHEINISCHE FRIEDRICH-WILHELMS-UNIVERSITAT BONN";"IE;BE;IT;DE";;1;0;0;1;0;0 199143;691164;ASTROSTAT;SIGNED;H2020-EU.1.3.3.;MSCA-RISE-2015;H2020;Development of Novel Statistical Tools for the Analysis of Astronomical Data;2016-01-01;2019-12-31;;We propose an interdisciplinary collaboration network involving leading groups in Astrophysics (Astrophysics Group in Crete, Geneva Observatory, Smithsonian Astrophysical Observatory, Ohio State University. and Nortwestern University), and Statistics (Imperial College, University. of California Davis). The goal of this project is to share expertise between the different fields and geographical areas in order to tackle key questions in observational Astrophysics, related to the nature of dark energy and dark matter, the populations of accreting binary stars in galaxies and their evolution, and the morphological and activity classification of galaxies. To address each of these questions we will use state-of-the-art observations and theoretical models, and we will develop novel, principled tools for statistical analysis in the domains of source classification, structure detection, and fitting. The methods developed under this program will have lasting value and applications beyond the field of Astrophysics.;652500;526500;H2020-MSCA-RISE-2015;/MSCA-RISE;FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS;EL;"IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE;UNIVERSITE DE GENEVE";"UK;CH";;1;0;0;1;0;0 198199;656636;Titin Signals;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2014-GF;H2020;Molecular dissection of titin-based mechanisms in charge of cardiomyocyte dysfunction in terminal feart failure;2016-07-01;2019-06-30;;"Chronic heart failure is a leading cause of mortality in the industrialized countries. Pathomechanistically, a variety of diverse stress signals on the cardiomyocyte trigger loss of myofibrils and cardiomyocyte death, thereby activating a vicious cycle of cardiac stress and deterioration during terminal heart failure. Despite the enormous clinical relevance, the exact pathomechanisms in charge remains unclear. Here, I propose to investigate the molecular mechanisms that couple mechanical cardiomyocyte strain and cardiomyocyte loss during the heart failure involving the mechanosensing titin filament. For this, I will perform research in three globally leading teams and access their complementary expertise in a secondment scheme. In the the proposed 2-year outgoing phase, I will study how cardioprotection is mediated by key factors recently identified in the Ju Chen lab (UCSD, San Diego). During this time, I will be trained in cutting-edge molecular mouse genetic models and phenotyping tools. This research is expected to shed light on CARP-titinsignaling axis in cardiomyocyte death and to provide tools for manipulating this pathway. In a one-year re-integration phase I will perform follow-up mechanistic structural studies in the Olga Mayans lab (University of Liverpool) to determine the structural basis how the CARP (cardiac ankyrin repeat protein)-titin signaling axis mediates cardiomyocyte protection, and in the Labeit lab (University of Heidelberg, Medical Faculty Mannheim) how to perturb activity of this complex by small molecules. Taken together, this work encompasses structural studies at the atomic level up to vivo animal models to study CARP-titin functions. After the propose three years, I expect to be ready to pursue an independent career in the field of molecular cardiology research. Therefore, my goal during the re-integration phase will be to set-up an interdisciplinary collaboration involving the three lead teams of this proposal.";239860,8;239860,8;H2020-MSCA-IF-2014;/MSCA-IF-GF;ZENTRALINSTITUT FUER SEELISCHE GESUNDHEIT;DE;RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG;DE;;1;0;0;1;0;0 196934;664386;ICRI-BioM;SIGNED;H2020-EU.4.a.;WIDESPREAD-1-2014;H2020;International Centre for Research on Innovative Bio-based Materials;2015-06-01;2016-05-31;;"The aim of this project is to establish a new centre of excellence in the Lodzkie Region, Poland, by creative and collaborative efforts, i.e. TEAMING with Max Planck Society (MPS), Germany, as the internationally leading institution. The planned International Centre for Research on Innovative Bio-based Materials (ICRI-BioM) will focus on design, synthesis, characterization and practical implementations/applications of advanced materials, exemplified by biomaterials, bio-products, and multifunctional smart polymer systems. This program fits into the Regional Strategy of the Lodzkie Region as one of smart specialisations, represented in the regional strategic documents, as well as the national strategy. An added value will be the synergistic effect created by combining expertise and ambitions of main research institutes in this area from Lodzkie Region and MPS. During the first year, a strategic Action Plan will be created with teaming partners and other participants: industry, research, regional and national authorities. The proposed Business Plan will describe a vision for the establishment of the ICRI-BioM: (i) long-term science and innovation strategy; (ii) organizational and management structure; (iii) a legal form of independent, autonomous non-profit institution; (iv) all required operational regulations. At the first stage of its activities, ICRI-BioM will be supported by national and regional funds, European structural and investment funds, Horizon 2020 and research, innovation and competitiveness Union - related programs. Within several years, the ICRI-BioM will become the strategic interdisciplinary research centre and it will influence the economic development of the region and country. By teaming with MPS, as the best European research institution, we trust that ICRI-BioM will be able to mimic the best research practices, adopt them into Polish reality and re-invent and re-shape the Polish research landscape.";494375;494375;H2020-WIDESPREAD-2014-1;/SGA-CSA;NARODOWE CENTRUM BADAN I ROZWOJU;PL;"MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;POLITECHNIKA LODZKA";"DE;PL";;1;0;0;1;0;0 202773;702293;MuCellWall;CLOSED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Seed mucilage envelope as a new structural model in cell wall research;2016-09-01;2018-08-31;;The plant cell wall is dynamic, complexes structure composed of polysaccharides divided into fibrillar (cellulosic) fraction and extracellular matrix (hemicelluloses and pectins). All the components are arranged in a network structure characteristic of the cell wall. The proposed, general spatial models of the cell wall based mostly on various biochemical and/or microstructural analysis, which have usually been invasive by treatment with enzymes or chemicals, which can destroy the cell wall organization and allow to visualize a selected components. Despite of extensive research our knowledge about the cell wall is still incomplete and restricted mostly to the biochemical or genetic studies. The main aim of this project will be the determination of the cell wall components i.e. polysaccharides, glycoproteins, and the determination their spatial distribution in a special type of cell wall of the mucilage secreting cells (MSCs). The obtained results will allow creation a direct spatial cell wall model. The used material e.g. seeds of Arabidopsis thaliana mutants and wild type, Artemisia leucodens or Lepidium sativum will be an excellent and so far not examined study model due to characteristic loose spatial structure of the MSC cell wall. The use of modern techniques (in a quite new combinations) e.g. antibodies with attached gold particles and precise visualization in divers microscopes (e.g. SEM, LCSM) available at the host laboratory (Kiel University) will allow to overcome invasive procedures and let to detect the exactly location of the components. The realistic, representative cell wall spatial model will be created allowing for better understanding the different processes taking place within the cell wall. The project will be implemented at an interdisciplinary level opening a new possibilities for various cell wall studies. The project will give a new insight into the cell wall structural studies and lead to significant advances in this field.;171460,8;171460,8;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;CHRISTIAN-ALBRECHTS-UNIVERSITAET ZU KIEL;DE;;;;1;0;0;1;0;0 200450;704459;HYBOCOMIX;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Hydrogen bonds in diblock copolymer/ homopolymer melt;2016-09-01;2018-08-31;;"HYBOCOMIX is focused on a combined theoretical and experimental study of the phase behavior of a blend of an AB diblock copolymer with homopolymer A. where polymer A repeat units can form hydrogen bonds with each other. A completely new self-consistent field theory (SCFT) model will be developed to describe the influence (in such block copolymer systems) of hydrogen bond formation on the block copolymer self-assembly of ordered phases. This model will be exploited to study, both theoretically and experimentally, the phase behavior of an exemplar system; a mixture of polyacrylamide-b-polystyrene (PAM-b-PS) with polyacrylamide (PAM), where polyacrylamide is the hydrogen bonding polymer. The key feature of this interdisciplinary project is in close connection between experiment and theory which will; (i) allow the study of a system that is completely new both from experimental and theoretical points of view and (ii) access model parameters directly from experiment in the framework of a project to provide unequivocal quality for the verification of the new HYBOCOMIX theory. Potential applications of block copolymers with hydrogen bonds are really abundant and include drug delivery applications, self-healing materials, nanolithography and patterning for microelectronics. The success of this project will open the room for future application developments and research of more complex block copolymer systems with hydrogen bonds providing a new widely applicable theoretical method to predict the structure of block copolymers with hydrogen bonds.";195454,8;195454,8;H2020-MSCA-IF-2015;/MSCA-IF-EF-CAR;ASTON UNIVERSITY;UK;;;;1;0;0;1;0;0 204851;694893;SENSOTRA;SIGNED;H2020-EU.1.1.;ERC-ADG-2015;H2020;Sensory Transformations and Transgenerational Environmental Relationships in Europe, 1950–2020;2016-08-01;2021-07-31;;This project aims at producing new understandings of the changes in people’s sensory environmental relationships in three European cities during a particular period in history, 1950–2020. It will offer a focused window on cultural transformations of the sensory by introducing a new transgenerational methodology, ethnographic “sensobiography”. Why now? Firstly, innovative and thoroughly researched information about sensory environmental relationships is in great demand. If the findings are successful, their challenge to several conventional dichotomies will provide results whose interdisciplinary impact extends beyond cultural, sound, and music studies to areas of psychology, human geography, environmental aesthetics, and media history and theory. The research is urgent: at present we are still able to study people ethnographically who were born in the 1930s and 1940s,who therefore lived their early years without digital technologies. The moment is also ideally suited for studying generations born straight into the digital world, where there is a need to enable young and older people to maintain a many-faceted relationship with their environments. The project's three research strands are (1) transformations in mediations of sensory experience, (2) embodied remembering and senses, and (3) sensory commons. These strands will be studied via a research strategy linking individuals and groups to broader social, cultural, and political issues in the medium-sized European cities of Brighton (UK), Ljubljana (Slovenia), and Turku (Finland). Temporally and spatially tightly focused dynamic ethnography makes it possible to examine multiple modes of past and present sensory experiencing. The study of artists as “sensewitnesses” will become one of the pivotal endeavours. The project facilitates a significant step from earlier methodologies toward large-scale, multisensory, transgenerational investigation, providing significant insights into culture with a sustainable future.;1860264;1860264;ERC-2015-AdG;/ERC-ADG;ITA-SUOMEN YLIOPISTO;FI;UNIVERSITY OF BRIGHTON;UK;;1;0;0;1;0;0 195368;656988;NEDBELS;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2014-GF;H2020;NEURODIVERSITY BETWEEN LAW AND SCIENCE;2015-09-01;2018-08-31;;The aim of the research proposal “Neurodiversity between Law and Science” (NEDBELS) is to inquire into the legal impacts and socio-political implications of the concept of neurodiversity. This term pertains to individuals diagnosed with neurodevelopmental disorders such as Asperger’s Syndrome and Autism and hypothesizes the emergence of a new category of difference in the human population. NEDBELS explores how this concept challenges the constitutional principle of equality, as well as how it fosters the need to accommodate new principles in criminal and civil law. This proposal has risen from a need for heightened communication between law and science. Scientific theories, concepts and methods widely permeate law and adjudication, and legal and ethical frameworks intimately drive applied sciences, as in education and health care systems. Therefore, one might reasonably expect that these two worlds would cooperate on a regular basis. However, lawyers, scientists and health care professionals operate largely insulated from one another in research, formal training and daily practice. This divergence prevents vulnerable minorities, such as people with neurodevelopmental disorders, from reaping the full socio-political potential of scientific advancements. NEDBELS’s goal is to increase communication between law and neurosciences through interdisciplinary research methodologies and scientific training-through-research as well as by enhancing the synergy among legal experts, policy makers and scientists in the field of neurodiversity;159034,56;159034,56;H2020-MSCA-IF-2014;/MSCA-IF-GF;ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA;IT;;;;1;0;0;1;0;0 220398;801936;HYPROTIN;SIGNED;H2020-EU.1.1.;ERC-2018-STG;H2020;Hyperpolarized Nuclear Magnetic Resonance Spectroscopy for Time-Resolved Monitoring of Interactions of Intrinsically Disordered Breast-Cancer Proteins;2019-03-01;2024-02-29;;"HYPROTIN proposes a pioneering research platform for hyperpolarized magnetic resonance of breast-cancer related proteins that will revolutionize our view on tumorigenesis at the atomic level, through bottom-up reconstitution of medicinal relevant interaction pathways involving the breast cancer susceptibility protein 1 (BRCA1). The risk to develop a hereditary breast or ovarian cancer (HBOC) increases to 55-65 % upon mutation of the BRCA1 gene. Yet, little is known about the biochemistry of tumorigenesis, so that drugs directed towards molecular targets are not satisfactory. To date, mastectomy remains the only preventive treatment. This dramatic lack of knowledge is a consequence of BRCA1 being an intrinsically disordered protein (IDP). Recognizing the importance of IDPs has revolutionized structural biology in the last decade, but this also represents a huge experimental challenge. To date, nuclear magnetic resonance (NMR) is the only technique available to study IDPs at high resolution. However, several limits of the technique must be overcome. Its low sensitivity impedes investigations under biologically meaningful conditions, so that new approaches are required. The HYPROTIN project aims to achieve two methodological goals: 1) Residue-resolved studies of the BRCA1 IDP under physiological conditions; and 2) real-time monitoring of BRCA1-ligand binding, thereby adding a time-resolved dimension to the NMR characterization of IDPs. This systematic approach will provide unprecedented insight into the BRCA1 interactome, provide medically relevant data and residue-resolved protein interaction kinetics. This will open a new knowledge base for rational drug design. The project will employ cutting-edge equipment that is unique worldwide, and will represent the first facility in Europe suited for these ground-breaking experiments. The PI has unique interdisciplinary experience enabling the demanding hyperpolarization approach to IDPs.";1990728;1990728;ERC-2018-STG;/ERC-STG;UNIVERSITAT WIEN;AT;;;;1;0;0;1;0;0 207594;714868;EmergingWelfare;SIGNED;H2020-EU.1.1.;ERC-2016-STG;H2020;The New Politics of Welfare: Towards an “Emerging Markets” Welfare State Regime;2017-01-01;2021-12-31;;"This research project aims to identify a new welfare regime in emerging market economies and explain why it has emerged. The project will compare Brazil, China, India, Indonesia, Mexico, South Africa and Turkey to test two hypotheses: (i) emerging market economies are forming a new welfare regime that differs from liberal, corporatist and social democratic welfare regimes of the global north on the basis of extensive and decommodifying social assistance programmes, (ii) the new welfare regime emerges principally as a response to the growing political power of the poor as a dual source of threat and support for governments. Based on a comparative and interdisciplinary perspective, the project follows a multi-method strategy that combines state-of-the-art computer-based protest event data collection techniques, macro-historical methods, quantitative data analyses and qualitative content analysis. The project will radically expand the literatures on welfare regimes, welfare state development and contentious politics, by challenging the existing paradigms dominated by structuralist perspectives, a myopic focus on Western countries, and limited data collection and analysis techniques. This project is genuinely innovative, unprecedented, ground-breaking, ambitious and high-risk/high-gain in three ways: (i) it re-shapes the welfare regimes literatures as the first study to classify and explain welfare systems of emerging markets as a new welfare regime and (ii) the project demonstrates a causal link between changes in grassroots politics and welfare policies and challenge the structuralist preponderance in the existing welfare state development literature (iii) it makes a prodigious contribution to our empirical knowledge on contentious politics in emerging markets by creating the first cross-national databases on protest event, employing state-of-the art computer methods, such as natural language processing and machine learning, on newspaper archives.";1494240;1494240;ERC-2016-STG;/ERC-STG;KOC UNIVERSITY;TR;;;;1;0;0;1;0;0 204142;683253;GraphInt;SIGNED;H2020-EU.1.1.;ERC-CoG-2015;H2020;Principles of Graph Data Integration;2016-08-01;2021-07-31;;The present proposal tackles fundamental problems in data management, leveraging expressive, large-scale and heterogeneous graph structures in order to integrate both unstructured (e.g., text) and structured (e.g., relational) content. Integrating heterogeneous content has become a key hurdle in the deployment of Big Data applications, due to the meteoric rise of both machine and user-generated data storing information in a variety of formats. Traditional integration techniques cleaning up, fusing and then mapping heterogeneous data onto rigid abstractions fall short of accurately capturing the complexity and wild heterogeneity of today’s information. Having closely followed the emergence of heterogeneous information sources online, I am convinced that only an interdisciplinary approach drawing both from classical data management and from large-scale Web information processing techniques can solve the formidable data integration challenges that they pose. The following project proposes an ambitious overhaul of information integration techniques embracing the scale and heterogeneity of today’s data. I propose the use of expressive and heterogeneous graphs of entities to continuously and dynamically interrelate disparate pieces of content while capturing their idiosyncrasies. The following project focuses on three core issues related to large-scale and heterogeneous information graphs: i) the effective extraction of fined-grained information from unstructured sources and their proper integration into large-scale heterogeneous and probabilistic graphs, ii) the creation of novel physical storage structures and primitives to durably and efficiently manage the profusion of data considered by such graphs using clusters of commodity machines, and iii) the development of logical data abstraction mechanisms facilitating the effective and efficient resolution of complex analytic and data integration queries on top of the physical layer.;1998339;1998339;ERC-2015-CoG;/ERC-COG;UNIVERSITE DE FRIBOURG;CH;;;;1;0;0;1;0;0 200363;706314;GRAPHIL;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Exploring the Interface Between Ionic Liquids and Graphene : Elucidating Structure and Electronic Properties;2016-03-01;2018-02-28;;"GRAPHIL aims at generating a detailed picture of the lateral nanostructure of the ionic liquid (IL)-graphene interface. A special focus will be given to the understanding of the IL-graphene interactions that generate the interfacial structure and to the influence of IL on graphene electronic structure. This understanding will greatly benefit the research on IL/graphene based energy storage devices. State-of-the-art amplitude-modulated atomic force microscopy (AM-AFM) will be employed to visualize the lateral arrangement of cations and anions for a series of ionic liquids in order to establish the correlation between the constituent ions and the interfacial structure of IL on graphene. The structure will be compared for biased as well as unbiased graphene substrates. Raman spectroscopy will be used to establish the dependence of IL structure on the electronic structure of graphene. This highly interdisciplinary research that lies at the interface of chemistry, material science and surface science will be carried out at KU Leuven-University of Leuven (experimental work, in the group of Prof. Steven De Feyter) and will be complemented by theoretical simulations carried out at University of Mons (in group of Prof. Roberto Lazzaroni) and University of Antwerp (in the group of Prof. Francois Peters)";172800;172800;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;KATHOLIEKE UNIVERSITEIT LEUVEN;BE;;;;1;0;0;1;0;0 219007;826025;Energy-SHIFTS;SIGNED;H2020-EU.3.3.;LC-SC3-CC-4-2018;H2020;Energy Social sciences & Humanities Innovation Forum Targeting the SET-Plan;2019-04-01;2021-03-31;;"Energy-SHIFTS “Energy Social sciences & Humanities Innovation Forum Targeting the SET-Plan” will contribute to a European Energy Union that places societal needs centrally, by further developing Europe’s leadership in using and applying energy-related Social Sciences and Humanities (energy-SSH). Our consortium brings together 4 leading interdisciplinary research institutes with 3 highly respected policy, industry and communications organisations from across the energy-SSH field, to create an innovative and inclusive Forum. Our partners have significant energy-SSH H2020 project experience, direct working links with the EU’s Strategic Energy Technology Plan (SET-Plan) communities, extensive networks in the energy domain, and represent excellent coverage across SSH disciplines and across Europe. These will enable us to maximise the impact of our Forum delivery within an intensive 2-year project. Energy-SHIFTS activities will target over 10,000 stakeholders and begin with scoping activities including: accessible guides to SSH in EU policy; workshops on SSH priority themes; online policyworker and researcher databases. We will build on this scoping work to implement: 4 Working Groups across SET-Plan themes; a Policy Fellowship scheme; an Early-Stage Researcher programme; masterclasses for policy, NGO, STEM, and media audiences; 4 online citizen debates; and a pan-European conference. Our consortium will bring their considerable expertise in research-policy dialogue to these activities. Our core activities will both provide immediate insights for the short-term directions of EU energy policy as well as foundations for longer-term mechanisms that will enable evidence-based energy-SSH insights to reach the ‘policy front line’. As a central body bringing SSH communities together, we will work to directly inform future FP9 and SET-Plan priorities. Energy-SHIFTS will significantly enhance the policy impact of energy-SSH, and accelerate shifts to low-carbon energy systems.";1014560;1014560;H2020-LC-SC3-2018-Joint-Actions-3;/CSA;ANGLIA RUSKIN UNIVERSITY HIGHER EDUCATION CORPORATION;UK;"ACENTOLINE COMUNICACION EDITORA SL;ALLIANCE EUROPEENNE DE RECHERCHE DANS LE DOMAINE DE L'ENERGIE;NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU;DUTCH RESEARCH INSTITUTE FOR TRANSITIONS BV;E3G ASBL;UNIWERSYTET JAGIELLONSKI";"ES;BE;NO;NL;PL";;1;0;0;1;0;0 219678;825785;PD_Pal;SIGNED;H2020-EU.3.1.3.;SC1-BHC-23-2018;H2020;Palliative care in Parkinson’s disease;2019-01-01;2022-06-30;;"Parkinson’s Disease (PD) is the second most common neurodegenerative disorder and is characterized in its advanced stages by motor and non-motor complications causing progressive loss of autonomy in activities of daily living, poor quality of life, marked caregiver distress, and high utilization of medical services. Similar to cancer patients, albeit for much longer duration, PD patients have considerable (and mounting) unmet physical, psychosocial and spiritual needs, and experience great problems with continuity of care. The overall ambition of PD_Pal is to validate a new model of palliative care which would be easily integrated with traditional management when disability limits mobility and independence. PD_Pal will provide an added layer of support to patients, their loved ones, and treating clinicians. PD_Pal randomised controlled trial will provide evidence on the effectiveness of specialized, multidisciplinary, outpatient palliative care intervention (Advance Care Planning) in improving family satisfaction, symptom management and quality of life. PD_Pal will also further prove the feasibility and economic sustainability of this approach by the active involvement of patients lay associations as well relevant medical societies. PD_Pal team includes leading experts in both neurology and palliative care with key-roles in both national and international PD working groups. PD_Pal will develop a new set of evidence-based Guidelines and a Massive Online Course (MOOC) for Palliative Care in PD involving in the process experts from the European Association for Palliative Care, the European Academy of Neurology and the Movement Disorders Society. Thus, PD_Pal is best positioned to transfer this knowledge to all European countries and ensure that “PD_Pal Guidelines” will translate into best practice. The PD_Pal MOOC “Best Care for People with Late Stage Parkinson” will be integrated into the WHO supported interdisciplinary post-graduate palliative care curriculum.";3995437,5;3995437,5;H2020-SC1-2018-Single-Stage-RTD;/RIA;UNIVERSITA DEGLI STUDI DI PADOVA;IT;"PHILIPPS UNIVERSITAET MARBURG;STICHTING KATHOLIEKE UNIVERSITEIT;EESTI LIIGUTUSHAIRETE SELTS;PD NEUROTECHNOLOGY LTD;PANEPISTIMIO IOANNINON;UNIVERSITY COLLEGE LONDON;PARACELSUS MEDIZINISCHE PRIVATUNIVERSITAT SALZBURG - PRIVATSTIFTUNG;KING'S COLLEGE LONDON;MEDIOLANUM CARDIO RESEARCH SRL";"DE;NL;EE;UK;EL;AT;IT";;1;0;0;1;0;0 218683;824072;HARVESTORE;SIGNED;H2020-EU.1.2.2.;FETPROACT-01-2018;H2020;Energy HarveStorers for Powering the Internet of Things;2018-12-01;2023-11-30;;A breakthrough in micro-energy harvesting and storage technologies is required to cover the increasing demand of autonomous wireless sensor nodes (WSN) for the future Internet of Things (IoT), which is considered one of the five technologies that will change the world by connecting 27 billion devices and generating €2 trillion market by 2025. The HARVESTORE project aims to power these IoT nodes from ubiquitous heat and light sources by using nano-enabled micro-energy systems with a footprint below 1cm3. Using disruptive concepts from the emerging Nanoionics and Iontronics disciplines, which deal with the complex interplay between electrons and ions in the nanoscale, a radically new family of all-solid state micro-energy sources able to harvest and store energy at the same time will be developed. This new devices will be called “?-harvestorers” (?HS). In order to enable this science-to-technology breakthrough, our nano-enabled ?-HSs will be integrated in silicon technology. This will allow reaching the highly dense features and scalability required for a real miniaturization and massive deployment that will show their viability as a new technological paradigm of embedded energy. The HARVESTORE project addresses this challenging objective by building an interdisciplinary research consortium that includes consolidated and emergent leading researchers in modelling, microfabrication, materials science and energy together with high-tech pioneer SMEs with unique capabilities to develop and deploy IoT nodes for real applications. Moreover, the structure and communication strategy have been designed to make HARVESTORE a lighthouse project for boosting this novel micro-energy paradigm and building around an innovation ecosystem founded on emerging Nanoionics and Iontronics applied to energy.;7006200;7006200;H2020-FETPROACT-2018-01;/RIA;FUNDACIO INSTITUT DE RECERCA DE L'ENERGIA DE CATALUNYA;ES;"TECHNISCHE UNIVERSITAET WIEN;COVENTRY UNIVERSITY;IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE;INTERUNIVERSITAIR MICRO-ELECTRONICA CENTRUM;HORIBA FRANCE SAS;AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS;DANMARKS TEKNISKE UNIVERSITET;WORLDSENSING SL;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;ALTERNATIVE ENERGY INNOVATIONS SL";"AT;UK;BE;FR;ES;DK";;1;0;0;1;0;0 219243;824007;iP-OSTEO;SIGNED;H2020-EU.1.3.3.;MSCA-RISE-2018;H2020;Induced pluripotent stem cell seeded active osteochondral nanofibrous scaffolds;2019-02-01;2023-01-31;;"iP-OSTEO project focuses on development of novel cell-based scaffolds for bone and cartilage repair in patients with poor regenerative capacity. We are proposing technology combining iPSCs with improved regeneration capacity combined with nanostructured scaffolds based on electrospun scaffolds and drug delivery system stimulating cell regeneration based on electrosprayed and spray-dried particles. The system will deliver novel treatment method for older patients, for which the current cellular and cell-free methods are ineffective. iP-OSTEO will reach its goals by creating an international and interdisciplinary training program. 7 companies (SMEs) and 7 academic institutions across European Union will join there forces though dedicated secondments. The activities will involve networking, research/training, workshop and dissemination secondments. The project has in total 239 secondments involving exchange of Early-stage and Experienced researchers. The consortium is bonded by Dr. Eva Filova – young scientist with experience in bone and cartilage tissue engineering. The iP-OSTEO project will help in better integration of academic and industrial stakeholders across Europe and help diseased people by providing novel therapeutic methods. Nevertheless, project has 169 ESR secondment months leading to training of new generation of scientists with international connection and knowledge of intrasectorial enviroment.";1099400;1099400;H2020-MSCA-RISE-2018;/MSCA-RISE;USTAV EXPERIMENTALNI MEDICINY AKADEMIE VED CESKE REPUBLIKY VEREJNA VYZKUMNA INSTITUCE;CZ;"OSPIN GMBH;ORTHOSERA GMBH;HOCHSCHULE RHEIN-WAAL-HSRW RHINE-WAAL UNIVERSITY OF APPLIED SCIENCES;BIONEER A/S;FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.;LLS ROWIAK LASERLABSOLUTIONS GMBH;BIOFABICS LDA;SCINUS CELL EXPANSION BV;INSTYTUT PODSTAWOWYCH PROBLEMOW TECHNIKI POLSKIEJ AKADEMII NAUK;SZECHENYI ISTVAN UNIVERSITY;UNIVERSITY COLLEGE LONDON;INOCURE SRO;CORTICALIS AS";"DE;AT;DK;PT;NL;PL;HU;UK;CZ;NO";;1;0;0;1;0;0 219155;822682;POPREBEL;SIGNED;"H2020-EU.3.6.1.1.;H2020-EU.3.6.1.2.";GOVERNANCE-03-2018;H2020;Populist rebellion against modernity in 21st-century Eastern Europe: neo-traditionalism and neo-feudalism;2019-01-01;2021-12-31;;"POPREBEL is an inter-disciplinary consortium of researchers focused on explaining and contextualising the recent rise of populism in Central and Eastern Europe (CEE). While populism is a phenomenon that has by now emerged in almost every democracy, we believe that regional and cultural-historical dimensions need to be considered in order to improve not only scholarly knowledge, but also policy recommendations. It is urgent for Western Europeans to look into the CEE mirror, just as it is urgent for the CEE region to understand itself. To this end, we will create a typology of populism’s various manifestations, reconstruct trajectories of its growth and decline, investigate its causes, interpret its meanings, diagnose its consequences, and propose policy solutions. Our focus is on CEE, but we engage in comparisons with populisms elsewhere, particularly Western Europe. While scholars from different disciplines have looked at populism, we argue that the full potential of interdisciplinary research has not been achieved yet. We draw on data and models from various disciplines and combine them into a rich study of forces at play. In addition to established methods of economics, sociology, and cultural studies, at the heart of our approach is a novel methodology whose essence is a large-scale, Europe-wide, multi-lingual online conversation. This is a listening exercise; its aim is a deep understanding of everyday life in Europe challenged by the rise of populism. The method to process this unique ethnographic material is semantic social network analysis. POPREBEL relies on foresight/future studies, deep involvement with activists, policy makers, and civil society actors to boost the immune system of European democracy. We develop scenarios and share them with all interested parties to reflect, in public debate, on how well they fit both in the CEE region and the rest of Europe. Our focus is not just scholarly; the project serves as a platform for mutual learning.";2997961,25;2997961,25;H2020-SC6-GOVERNANCE-2018;/RIA;UNIVERSITY COLLEGE LONDON;UK;"EDGERYDERS OU;TARTU ULIKOOL;BUDAPESTI CORVINUS EGYETEM;UNIVERZITET U BEOGRADU - Filozofski fakultet;UNIVERZITA KARLOVA;UNIWERSYTET JAGIELLONSKI";"EE;HU;RS;CZ;PL";;1;0;0;1;0;0 218528;813979;Secreters;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2018;H2020;A new generation of microbial expression hosts and tools for the production of biotherapeutics and high-value enzymes;2019-01-01;2022-12-31;;"The ‘SECRETERS’ partnership aims to bring about a step change in the production of recombinant proteins, particularly Biotherapeutics and Industrial Enzymes. Both are critical products for the EU biotechnology sector, with combined markets in excess of $140 billion p.a.; the former are essential for the treatment of major diseases whereas the latter permeate every aspect of our daily life. Many proteins in these categories pose severe problems in production, especially disulphide-bonded proteins and new format 'difficult-to-express' proteins. SECRETERS will train a team of 15 ESRs to develop a new generation of super-producing microbial production hosts, including Escherichia coli, Bacillus species and the yeast Pichia pastoris. The project capitalises on a series of recent innovations and involves close collaboration between 5 academic Beneficiaries, who provide world-leading expertise in redox chemistry, synthetic biology and protein expression, and 5 non-academic Beneficiaries, who include some of the world's premier biotherapeutic and industrial enzyme companies. It will enable the biotherapeutics industry to produce challenging medicines at lower costs, resulting in new drugs and wider patient access, and allow the enzymes industry to deliver a range of powerful new products. SECRETERS will equip ESRs with the interdisciplinary and intersectoral skills required to thrive in these industries, with quality assurance systems embedded throughout the programme and a commitment to a wide-ranging dissemination/outreach programme. Based on a responsible innovation approach, with clear foci on research and entrepreneurial training, SECRETERS will deliver a team of superbly-trained scientists, poised to engage in some of Europe's most important biotechnology sectors.";4087420,92;4087420,92;H2020-MSCA-ITN-2018;/MSCA-ITN-ETN;ACADEMISCH ZIEKENHUIS GRONINGEN;NL;"OULUN YLIOPISTO;UCB PHARMA SA;UNIVERSITATSMEDIZIN GREIFSWALD KORPERSCHAFT DES OFFENTLICHEN RECHTS;ACIB GmbH;LONZA AG;AB Enzymes GmbH;UNIVERSITY OF KENT;HUMBOLDT-UNIVERSITAET ZU BERLIN;BOEHRINGER INGELHEIM RCV GMBH & CO KG;UNIVERSITAET GREIFSWALD";"FI;BE;DE;AT;CH;UK";;1;0;0;1;0;0 218075;824043;ECOBOTICS.SEA;SIGNED;H2020-EU.1.3.3.;MSCA-RISE-2018;H2020;Bio-inspired Technologies for a Sustainable Marine Ecosystem;2019-01-01;2022-12-31;;"ECOBOTICS.SEA is a future-oriented 4-year research project with a research-driven human-resources training network in its center. ECOBOTICS.SEA focuses on the research of underwater robotics and biomimetics concepts and technology, targeting problems and needs in the real world that are related to the study of biospheres, species and ecosystems and their preservation. 8 Early-Stage Research Projects (ESRP) compose the research plan. The research to be carried out in these 8 ESRP is organized into 5 scientific work packages. The core of the research activities is constituted by 88 months of secondments within the partner network which are essential for ensuring the required knowledge and know-how transfer between the partners. The partner network is composed by 3 universities and R&D institutes and 3 companies located in European member states, plus 1 R&D in Third Countries. The consortium is highly interdisciplinary, aggregating excellence from various domains, including robotics,biomimetics for water/underwater systems, automation, biology, ecosystem preservation, entrepreneurship and anthropology applied to species preservation. Workshops, summer schools and international conferences serve as complementary measures, not only for further stimulating the exchange of knowledge and providing training, namely to the ESRs, but also for achieving the 4 scientific objectives as specified in the proposal. ECOBOTICS.SEA also incorporates a detailed and well defined career and risk management and training towards application-oriented R&D. Finally, the project is planned to establish an open community that will grow over time and enlarge its impact during and beyond the period of this project, resulting in a lasting, truly international R&D and business network beyond the project’s lifetime.";404800;404800;H2020-MSCA-RISE-2018;/MSCA-RISE;INSTITUTO DE SISTEMAS E ROBOTICA-ASSOCIACAO;PT;"EVOLOGICS GMBH;TRIDIVISIONS, LDA;FOBOS SOLUTIONS SL;TALLINNA TEHNIKAULIKOOL;INSTITUTO SUPERIOR TECNICO";"DE;PT;ES;EE";;1;0;0;1;0;0 218309;814249;DARE;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2018;H2020;Disability Advocacy Research in Europe;2019-01-01;2022-12-31;;DARE will train a new generation of disability scholars and policy specialists. It sets out an ambitious research programme, providing interdisciplinary, intersectoral training which will equip the ESRs to have a real impact on law and policy reform and on the real lives of persons with disabilities. The goal of DARE is to give legitimacy, through research, to the lived experience of persons with disabilities, as a basis for law reform. This is not just a desirable policy goal - it is legally required by the UN Convention on the Rights of Persons with Disabilities which is binding in the EU alongside its Member States. DARE innovates intersectorally by bringing non-academic partners into the very heart of the research and training programme as co-supervisors of the ESRs. It innovates intersectionally by emphasising how various identities (such as gender and age) interact to create layers of discrimination against persons with disabilities. It innovates by training the ESRs in emancipatory and participatory research methods to ensure that the voices of persons with disabilities take centre stage in the research process. It will require the ESRs to adopt a lifecourse perspective in developing an evidence base for law and policy reform. Through a carefully tailored secondment strategy in the advocacy community, DARE will expose the ESRs to organisations outside academia and at the epicentre of reform. DARE will draw on a panel of international policy & disability experts to enable the ESRs to continually refine their research to ensure it has societal impact. DARE will make Europe a highly attractive educational space for research on the implementation of the UN Convention. It will give the ESRs a decisive advantage in seeking new employment roles in processes of reform at the international level, before Governments and in advocacy groups. Its graduates will be seen not merely as traditional ‘knowledge providers’ but also as ‘policy entrepreneurs.’;4073765,4;4073765,4;H2020-MSCA-ITN-2018;/MSCA-ITN-ETN;NATIONAL UNIVERSITY OF IRELAND GALWAY;IE;"INSTITUTO SUPERIOR DE CIENCIAS SOCIAIS E POLITICAS;EUROPEAN DISABILITY FORUM AISBL;UNIVERSITEIT MAASTRICHT;UNIVERSITY OF LEEDS;Schweizer Paraplegiker-Forschung AG;HASKOLI ISLANDS;EUROPEAN ASSOCIATION OF SERVICE PROVIDERS FOR PERSONS WITH DISABILITIES";"PT;BE;NL;UK;CH;IS";;1;0;0;1;0;0 217992;813137;URBASIS;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2018;H2020;New challenges for Urban Engineering Seismology;2018-11-01;2022-10-31;;"Recent devastating earthquakes and induced seismicity near infrastructures must become the centrepiece of analysis in reducing risk and increasing resilience, facing up to global urban population growth in the coming decades and the concentration of wealth in cities. The prediction of seismic ground motion and response of structures are key issues in reduction of seismic urban risk. There is therefore a demand for highly trained scientists with a broad understanding of engineering seismology and earthquake engineering, skills being essential in academic research, in private companies with activities related to risk mitigation and energy facilities and for policy makers. The URBASIS project aims to provide a multi-disciplinary training platform for ESR in order to develop their individual project and to promote their entrepreneurship and their employability toward the academic, private and insurance or decision-making sector. High-quality supervision of the ESR will be ensured through the international recognition of the URBASIS partners. A comprehensive set of transferable skills will be developed through innovative and interdisciplinary joint research projects between academic and non-academic partners on the prediction of seismic hazard in urban areas considering low probability/high consequences events and induced seismicity related to the exploitation of energy resources; the seismic ground motion prediction within the non-free-field urban area; the coupling between ground motion and structures/infrastructures responses for natural and induced seismicity including time dependency vulnerability; and the systemic risk of interconnected urban systems. URBASIS will create a lasting collaboration for the establishment of a European network of academic and non-academic experts, improving the interface with decision-makers. Advanced capacities in modelling and predicting seismic impact in cities will be got, putting the urban environment as the centrepiece of URBASIS.";4066113,6;4066113,6;H2020-MSCA-ITN-2018;/MSCA-ITN-ETN;UNIVERSITE GRENOBLE ALPES;FR;"GEOTER SAS;ARISTOTELIO PANEPISTIMIO THESSALONIKIS;HELMHOLTZ ZENTRUM POTSDAM DEUTSCHESGEOFORSCHUNGSZENTRUM GFZ;ISTITUTO NAZIONALE DI OCEANOGRAFIA E DI GEOFISICA SPERIMENTALE;EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH;POLITECNICO DI MILANO;THE UNIVERSITY OF LIVERPOOL";"FR;EL;DE;IT;CH;UK";;1;0;0;1;0;0 217949;813789;CHANGE;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2018;H2020;Cultural Heritage Analysis for New GEnerations;2019-05-01;2023-04-30;;"Cultural heritage (CH) objects have been constantly undergoing changes/degradations over time. In order to pass the legacy of these objects to future generations, it is important to monitor, estimate and understand these changes as accurately as possible. These investigations will support the conservators to plan necessary treatments in advance or to slow down the specific deterioration processes. The dynamic characteristics of materials vary from one object to another and are influenced by several factors. To detect and predict their changes, accurate documentation and analysis are necessary. Over the years, CH digitization using scientific imaging techniques has become more widespread and has created a massive amount of datasets of different forms in 2D and 3D. Several past projects focused on different aspects of technological developments for better digitization methods. There has been less focus on the processing and analysis of these datasets to make the greatest use of them and to their further exploration for monitoring ‘changes’ in CH artefacts for conservation purposes. The lack of adequate digital tools for monitoring these changes is related to material behavior and stability, which still need to be addressed. The proposed project will take cultural heritage digitization to a new level by exploring digital datasets for deeper analysis and interpretation. The main idea is to develop methodologies for the assessment of changes in CH objects by comparing and combining digital datasets captured at different time periods. The validity of the methods has to be evaluated through case studies conducted in collaboration with CH experts and stakeholders. The project is an interdisciplinary approach combining expertise on imaging techniques, computing, CH, and conservation science.";4068821,16;4068821,16;H2020-MSCA-ITN-2018;/MSCA-ITN-ETN;NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU;NO;"TECHNOLOGIKO PANEPISTIMIO KYPROU;POLITECHNIKA WARSZAWSKA;Schweizerisches Nationalmuseum;UNIVERSITETET I OSLO;COMMUNAUTE D' UNIVERSITES ET ETABLISSEMENTS UNIVERSITE BOURGOGNE - FRANCHE - COMTE;HAUTE ECOLE SPECIALISEE DE SUISSE OCCIDENTALE;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;UNIVERSITEIT VAN AMSTERDAM";"CY;PL;CH;NO;FR;NL";;1;0;0;1;0;0 218573;799041;SUSTINNO;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Sustainability Innovations in Global Production Networks – Addressing Socio-Ecological Challengesin the Global Economy;2018-11-01;2021-10-31;;"In the 21st century,researchers, policy makers and practitioners are confronted with formidable environmental and societal mega problems. Sustainability innovations that address these issues are gaining stature in research and policy. The development of innovative and context-adapted solutions is a complex issue; how to develop sustainable solutions that adequately address local and global needs is the critical challenge of our times. The aim of the project is to investigate opportunities and barriers for more sustainable development processes in the global economy. This will be realized through a novel approach that integrates the Global Production Network (GPN) approach with concepts of innovation studies focusing on sustainability innovations. Conceptually, both of these research fields investigate how global environmental and socio-economic challenges can be addressed. However, their mutual engagement is hindered by different research paradigms, terminologies and concepts. By themselves the two research strands remain limited in explaining how sustainable solutions can be created, implemented and diffused in the global economy. My proposed project is located at the interface of these approaches. The overall research question asks how sustainability innovations can be developed and implemented within GPNs in order to address complex socio-ecological challenges, and facilitate better working conditions in the global economy. The objectives of this interdisciplinary project are: 1 To develop an integrated conceptual framework of sustainability innovations in GPNs. 2. To gain empirical insights on sustainability innovations in GPNs from a Global South perspective. 3. To derive and disseminate recommendations for policy makers and practitioners on how to address complex socio- ecological challenges. 4. To further my academic career by enhancing my skills and networks with the goal of securing a permanent academic position within the next five years.";203200,2;203200,2;H2020-MSCA-IF-2017;/MSCA-IF-GF;THE UNIVERSITY OF MANCHESTER;UK;;;;1;0;0;1;0;0 218048;812699;IMPROVE-PD;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2018;H2020;Identification and Management of Patients at Risk – Outcome and Vascular Events inPeritoneal Dialysis;2019-01-01;2022-12-31;;Peritoneal dialysis (PD) is an underused life saving renal replacement therapy for end-stage kidney disease. Nevertheless, PD patients remain at high risk for poor outcome, most notably excessive risk of cardiovascular disease. There is an unmet need for a risk-adjusted individualized PD approach. The IMPROVE-PD consortium provides 15 Early Stage Researchers (ESRs) in 11 partner institutes located in 7 different countries a state-of-the-art, multidisciplinary and intersectoral pan- European training programme including input from academic, clinical and industrial stakeholders. Network-wide and local training activities, individual research projects, intersectoral secondments and short laboratory visits will provide key generic skills and will prepare ESRs for future roles as highly skilled researchers in Europe. Well-phenotyped patient cohorts, and novel experimental models and techniques will be exploited by the ESRs, mentored by an excellent supervisory team, to improve future management of the PD patient at risk. This joint effort encourages productive collaboration between industrial and academic sectors though integrated projects and shared goals. Key findings will be communicated to a broad range of stakeholders through state of the art methods. IMPROVE-PD will give rise to a new generation of experts in PD with outstanding interdisciplinary research skills, intersectoral understanding and with perspective to pursue their careers in this scientific and industrial field. It will enable timely identification of the PD patient at high risk for adverse outcome, develop understanding of underlying pathomechanisms, and within an iterative process between research groups foster the development of innovative approaches to individualized treatment by targeting revealed pathomechanisms. Through these approaches, the ITN will achieve refinement of PD fluids, PD therapy and cardiovascular risk reduction.;4021380;4021380;H2020-MSCA-ITN-2018;/MSCA-ITN-ETN;AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS;ES;"UNIVERSITY OF KEELE;INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE;BAXTER MEDICAL PRODUCTS GMBH;ZYTOPROTEC GMBH;UNIVERSITE CATHOLIQUE DE LOUVAIN;EPSILON 3 GMBH;STICHTING VUMC;UNIVERSITAETSKLINIKUM HEIDELBERG;UNIVERSIDAD AUTONOMA DE MADRID;CARDIFF UNIVERSITY";"UK;FR;AT;BE;NL;DE;ES";;1;0;0;1;0;0 213421;765400;OCCAM;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2017;H2020;Outcomes and Causal Inference in International Comparative Assessments;2018-02-01;2022-01-31;;"The ETN OCCAM will investigate how educational policies influence educational outcomes worldwide. One of the most salient findings in the field of education is that there are huge national differences in student achievement in international comparative studies. The shockingly large gap between the highest performing countries (most of which are in East Asia) and many European countries corresponds to a difference in attainment of two years of schooling. Although this finding has been replicated in several studies, at present, the reasons for and consequences of such differences are not well understood. Variations in many features of educational policies can only be observed across countries on the system level (e.g., the existence of central exams). Since the start of the new millennium, a new generation of international comparative studies has been launched: studies like PISA and TIMSS are repeated every few years and thus have a longitudinal component at the system level. Unlike cross-sectional designs, these trend designs allow the causal effects of changes in educational policies at the system level to be estimated. Applying this approach, alongside other approaches to causal inference, to the accumulated data from the comparative studies has a huge potential to provide insights into the determinants of educational outcomes worldwide. The ETN will provide an ideal environment for training ESRs to become leading experts in educational policy evaluation, international student assessments, and educational and policy consulting. They will receive interdisciplinary and - intersectoral training, and their individual research projects promise groundbreaking new knowledge on how to design fair and efficient educational systems. For this purpose, OCCAM will integrate the complementary expertise from nine academic and three non-academic partners. The combination of non-profit and for-profit organizations will ensure the employability and entrepreneurship of the ESRs.";3882563,64;3882563,64;H2020-MSCA-ITN-2017;/MSCA-ITN-ETN;TECHNISCHE UNIVERSITAT DORTMUND;DE;"IFO INSTITUT LEIBNIZ INSTITUT FUR WIRTSCHAFTSFORSCHUNG AN DER UNIVERSITAT MUNCHEN EV;STICHTING I.E.A. SECRETARIAAT NEDERLAND;CITO BV;UNIVERSITETET I OSLO;UNIVERSITY COLLEGE LONDON;UNIVERSITY OF CYPRUS;KATHOLIEKE UNIVERSITEIT LEUVEN;GOETEBORGS UNIVERSITET";"DE;NL;NO;UK;CY;BE;SE";;1;0;0;1;0;0 211922;767195;HybridHeart;SIGNED;H2020-EU.1.2.1.;FETOPEN-01-2016-2017;H2020;Development of the first fully biocompatible, soft actuated heart: combining in situ tissue engineering and soft robotics;2017-11-01;2022-10-31;;"The Hybrid Heart consortium envisions to develop and bring to the clinic soft biocompatible artificial organs. These will consist of a soft robotics shell with actuators (‘artificial muscles’) and sensors, enabling completely natural motion. The inner lining and structures will be made by in situ tissue engineering (TE), ensuring biocompatibility of blood-contacting surfaces. As the first step, the consortium will develop the Hybrid Heart, which can completely replace a patient’s heart in a procedure similar to a heart transplant, to provide a cure for heart failure, which affects ~23 million people worldwide. Currently, patients with end-stage heart failure either receive a heart transplant, if available, or long-term mechanical circulatory support, which causes severe complications. To achieve the ambitious goal of providing a permanent cure for these patients, the participants will, in parallel, develop the components of the Hybrid Heart: 1) a soft elastomeric robotics shell containing actuators and sensors, 2) scaffolds for in situ TE of inner lining, valves and vessels and 3) a wireless energy transfer system. These components together will form the full Hybrid Heart, which will be soft, adaptable, wireless and fully bio- and hemocompatible. Both functionality as well as biocompatibility of the Hybrid Heart will be shown in a Proof-of-Principle study in the chronic sheep model at the end of the project. The Hybrid Heart project will be carried out by an interdisciplinary group of (academic) researchers and high-tech SMEs, with experience in cardiac surgery, TE, soft robotics and engineering. The technology underlying the Hybrid Heart is applicable to a range of soft robotics-based artificial organs, including the bowel, lung, or muscle structures (limbs). Replacing an entire organ with bioinspired robotic elements, TE biocompatible surfaces, artificial sensors, and an external power source allows for an off-the-shelf therapy for patients with organ failure.";3035550;3035550;H2020-FETOPEN-1-2016-2017;/RIA;Academisch Medisch Centrum bij de Universiteit van Amsterdam;NL;"SCUOLA SUPERIORE DI STUDI UNIVERSITARI E DI PERFEZIONAMENTO SANT'ANNA;DUALIS MEDTECH GMBH;TECHNISCHE UNIVERSITEIT EINDHOVEN;STICHTING NEDERLANDSE WETENSCHAPPELIJK ONDERZOEK INSTITUTEN;XELTIS BV";"IT;DE;NL";;1;0;0;1;0;0 207245;737043;TISuMR;SIGNED;H2020-EU.1.2.1.;FETOPEN-01-2016-2017;H2020;Integrated Tissue Slice Culture and NMR Metabolomics – A Novel Approach Towards SystemicUnderstanding of Liver Function And Disease;2017-01-01;2020-12-31;;"We propose the development of a groundbreaking technology platform that, for the first time, integrates nuclear magnetic resonance metabolomics and micro-imaging with microfluidic perfusion tissue slice culture. This will revolutionise life science research with unprecedented local insight into life processes in intact tissues under highly controlled conditions. We focus on liver tissue slice culture, with the immediate target of elucidating the mechanism of liver damage by drug-induced cholestasis. In the long term, the new technology will find wide application in other tissues, including intestinal, pancreatic, and brain slices. It will form the foundation of a new approach in the life sciences, allowing the detailed metabolic study of tissues at the system level. Liver disease is a significant and growing public health problem: 29 million people currently suffer from a serious liver condition in the EU. While the causes for some liver conditions are known, the mechanism of liver damage is generally poorly understood, largely due to the difficulty of studying live liver tissue at the systemic level. The proposed comprehensive research programme leads to a new technological platform for microfluidic tissue slice culture with direct observation of tissue metabolism and transport processes through nuclear magnetic resonance. It joins the expertise and creativity of four leading academic groups and one SME representing the disciplines of micro-engineering, physical chemistry, magnetic resonance, biochemistry, toxicology, and clinical hepatology across three institutions from three EU countries. Due to its high level of interdisciplinary integration, TISuMR is uniquely able to provide emerging researchers with a career springboard. TISuMR will have a profound impact on wider society by providing alternatives to animal testing, by increasing the efficiency and specificity of drug safety testing, and by enabling new treatments in the management of liver disease.";3138432,5;3138432,5;H2020-FETOPEN-1-2016-2017;/RIA;UNIVERSITY OF SOUTHAMPTON;UK;"KARLSRUHER INSTITUT FUER TECHNOLOGIE;RIJKSUNIVERSITEIT GRONINGEN";"DE;NL";;1;0;0;1;0;0 206902;692739;XSPECT;SIGNED;H2020-EU.1.1.;ERC-ADG-2015;H2020;Expecting Ourselves: Embodied Prediction and the Construction of Conscious Experience;2017-01-01;2020-12-31;;"This project (short name, XSPECT) aims to harness the emerging science of the predictive brain to deliver new insights into the nature, scope, mechanisms and (most importantly) the very possibility of conscious experience. The project thus explores and extends the vision of the brain as an inner engine continuously striving to predict the incoming sensory barrage. The key innovation is to consider this increasingly popular vision in the special context of embodied agents able to predict many of their own evolving states and responses – agents able to ‘expect themselves’. These crucial self-expectations span the interoceptive (targeting the internal sensory flows signaling our own physiological states, such as hunger, arousal, itch, and muscular and visceral sensations) and the exteroceptive (targeting the world, and our own behaviors as they might unfold over multiple scales of space and time). XSPECT explores the idea that such interacting states of complex, layered self-prediction hold the key to understanding much that is puzzling about conscious experience. The project is divided into three simultaneously active sub-projects. The first sub-project concerns relations between prediction, motor action, and experience. The second sub-project targets the role of interoceptive prediction in the construction of experience. The third sub-project considers ways in which more reflective forms of conscious experience (involving agency, selfhood, and the introspection of own experiential states) are further enriched by a spiraling array of socially mediated higher-level self-predictions. XSPECT will combine integrative philosophical argument, collaborative experimentation, and leading edge interdisciplinary research and discussion, leveraging two very successful but under-communicating research programs (‘embodied cognition’ and ‘the predictive brain’) to offer new perspectives on the puzzle of conscious experience.";1391134;1391134;ERC-2015-AdG;/ERC-ADG;THE UNIVERSITY OF EDINBURGH;UK;;;;1;0;0;1;0;0 205911;708068;PHOSPHOR;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-GF;H2020;Synthesis of Novel Phosphor Sensor Particles for Advanced Flame Diagnostics;2017-02-01;2019-07-31;;A longstanding problem in combustion research is that there is no means to simultaneously measure the temperature and velocity in high-temperature, chemically-reacting flows, which is essential to probe complex turbulence-chemistry interactions found in advanced combustion systems. The aim of this project is to solve this problem using a novel laser-based temperature-velocity imaging technique developed by the host organisation (Lehrstuhl für Technische Thermodynamik (LTT), Otto-von-Guericke Universität Magdeburg, Germany), which uses thermographic phosphor particles as a flow ‘tracer’. The primary objective of the action is to increase the measureable temperature range via synthesis of new phosphor particles optimised for flow temperature sensing. LTT will collaborate with the Advanced Combustion and Propulsion Lab (ACP), Princeton University, USA, who have developed innovative synthesis methods capable of producing phosphor particles with specific physical and optical properties. At ACP, the candidate fellow (LTT) will learn how to produce phosphors using these advanced methods, and then return to LTT where the new materials will be characterised and proven in flames. A laboratory for phosphor particle production and luminescence characterisation will be installed at LTT. The candidate fellow will develop unique, interdisciplinary expertise in thermographic phosphors, materials that will be at the forefront of future remote sensing technologies. The project will result in completely new measurement capabilities for fundamental and applied research, allowing the design of cleaner, fuel-efficient engines in key automotive, aerospace and power generation industries, thereby using fewer resources and reducing environmental impact. These novel materials will find use in lighting and display technologies and biological sensing, maximising both the impact of the action and opportunities for future collaboration with ACP and other EU research institutions and industry.;199828,2;199828,2;H2020-MSCA-IF-2015;/MSCA-IF-GF;OTTO-VON-GUERICKE-UNIVERSITAET MAGDEBURG;DE;;;;1;0;0;1;0;0 203520;708527;SmARTS;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Smart technology for analysis and monitoring of Cultural Heritage materials;2016-07-01;2018-07-28;;The recent advances in open-source and low-cost software and hardware are increasing the number of technologies based on the ‘sharing-knowledge’ philosophy, allowing users to develop their own instruments according to their analytical needs. The aim of SmARTS is to develop a device for inspection, monitoring and analysis of Cultural Heritage materials (objects and structure surfaces) by means of multi-analytical approaches based on a low-cost apparatus. The SmARTS device will be tested by monitoring the conservation state of a set of stained glasses from the Sagrada Familia church of Barcelona (Spain), as well as related metal frames. The device will be equipped with multiple sensors to acquire environmental data (temperature, humidity, etc.) as well as analytical data (UV-IR, thermal signals, colorimetric, etc.), and micro-cameras in order to integrate the collected data with real-time imaging. A software for signal processing and data mining completes the design. The innovation lies in the use of low-cost, open-source hardware and software, which allows a sustainable approach to Cultural Heritage preservation. The originality lies in the device’s modular architecture, conceived as a hub controlling different sensors modules which can be easily assembled or disassembled, so ensuring an extremely flexible analytical instrument, adaptable to different materials and contexts. SmARTS is highly committed to EU's strategy endorsed in the field of Cultural Heritage preservation, by promoting an interdisciplinary approach, and by proposing the application of cutting-edge science and technology . Moreover, SmARTS integrates the applicant’s knowledge in conservation science into a top level research team of the University of Vic (Spain), the MECAMAT, whose research focuses in material science and mechatronics with a strong commitment with the private sector. This will enhance the capacities to convert the research results into commercial opportunities.;170121,6;170121,6;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;FUNDACIO UNIVERSITARIA BALMES;ES;;;;1;0;0;1;0;0 203870;707763;FOODEV;CLOSED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Food and Gastronomy as leverage for local development;2016-05-12;2018-05-11;;"Food and gastronomy are increasingly recognized as elements of regional innovation strategies, contributing to regional and economic development both in rural and urban environments. On the other hand, in order to link research in food and gastronomy to that of sustainable development, it is necessary to draw from multiple disciplines, as food has a multifunctional character and the food system is heavily implicated in many public policy arenas. This proposal aims at implementing an inter-disciplinary research agenda able to determine under which conditions a certain place or region has been able to build on local features and to identify a successful sustainable development strategy based on food and gastronomy in the long-term. The project will consider the wider European policy debates on food and gastronomy as leverage for sustainable development, that will be coupled with systematic analysis of academic contributions on the topic across social and economic areas; explore factors contributing to sustainable development by the means of food and gastronomy in different projects/strategies, and according to different perspectives, will ensure to gain a systematic understanding of multiple issues and problems to be dealt with within each sector and how they interrelate, as emerging from each stakeholder category. This will build a more complex and network-like vision of knowledge, learning and innovation, which represent the concepts underpinning the emerging approach to knowledge transfer. The research action will develop reliable interdisciplinary evidence that can be used by policymakers to base their decisions on, contributing to closing the research and innovation gap through translational research approach, characterised by multi-disciplinary approaches allowing interaction between different spheres. This will contribute to the work programme by maximising experienced researcher’s contribution to knowledge-based economy and society.";173857,2;173857,2;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;GOETEBORGS UNIVERSITET;SE;;;;1;0;0;1;0;0 201399;706140;NARS;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Novel ecological adsorbent using Schwertmannite material for Removal of Selenate and Selenite from contaminated water;2016-05-01;2018-04-30;;"The purpose of this project is to test the suitability of recently developed schwertmannite adsorbents as filter bed materials as a new low-cost technique to remove selenite and selenate from mine water and agricultural drainage. The proposal deals also with critical societal and political issues like water management and sustainability as well as promoting good governance. To this end, an interdisciplinary approach combining hydrogeochemistry and technical development is implemented taking on consideration all the necessary steps of a novel ecological and low-cost water treatment technique. The project consists on two main components: 1) Filling knowledge gaps in the interaction of selenium oxyanions to schwertmannite adsorbents and how is it linked to the acidic pH, including the investigation of a separation method to reduce sorption competitiveness of sulphate towards selenate. 2) Optimising the performance of schwertmannite adsorbents to increase selenium removal rate. To set up a low-cost and eco-friendly process, the project will preform a regeneration study of the material, and explore the potential use of selenium generated from the process into glass-producing company. The fellow will benefit from a solid skill-set for a scientific career within academia, fruitful contact network for future and sustainable collaboration, as well as personal and cultural enrichment. The achievement of the project objectives will create a paradigm for clean and low-cost water treatment technologies, including water strategies, environmental policies and economic programmes.";159460,8;159460,8;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;UNIVERSITAET BAYREUTH;DE;;;;1;0;0;1;0;0 201362;705763;STUSOCSTA;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-GF;H2020;Students, social change and the construction of the post-independence Algerian state, 1962-1978;2016-09-01;2019-11-30;;"This project seeks to bring a new perspective to understanding state construction in Algeria after independence. Through a history of the first generations of Algerians who went to university in the 1960s and 1970s, it explores the intersections between political and institutional transformations and social, cultural and economic processes. These processes include increasing literacy, rural to urban migration, migration to study abroad and changes in gender relations and family structures. Bringing together concepts and methodologies from across a number of humanities and social science disciplines, the project will produce a case study setting out new approaches to studying state-building as a dynamic process which takes place at different levels of power (transnational, national and local) and which both shapes, and is shaped by, individual agency and wider processes. The goal is for this approach to be applicable to a range of other post-colonial contexts, challenging teleological readings of post-independence histories and homogenising understandings of post-independence states. The project is to be carried out in Algeria, France and the UK, with the researcher working with leading experts in the field in each of these countries to create a transnational, interdisciplinary network exploring the central research themes. Through extensive interviewing of former students, this project will create a new body of sources for researchers, which will also, with informants’ consent, be made accessible online. Public engagement is integral to the research design and process of data collection as well as dissemination, with Algerian students from the 1960s and 1970s invited to participate in group testimony sessions, alongside the wider public, throughout the project.";250104,6;250104,6;H2020-MSCA-IF-2015;/MSCA-IF-GF;UNIVERSITY OF PORTSMOUTH HIGHER EDUCATION CORPORATION;UK;;;;1;0;0;1;0;0 201367;705817;PYANO;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Retargeted Pyocins: A novel tool for combating major food borne pathogens and exploitingphage-host interactions;2016-06-01;2018-05-31;;Campylobacter jejuni and Salmonella serovars are the major foodborne pathogen burden of Europe, imposing economic costs and challenging treatment of human infections due to increasing antimicrobial resistance. Hence, the EU commission stresses an urgent need to develop new effective antimicrobials. Exploiting natural predators of bacteria (phages) or phage-derived products may be a source of such novel antimicrobials. But lack of genetic approaches to investigate phage binding mediated by receptor binding proteins (RBPs) hampers progress of phage therapeutics targeting C. jejuni and Salmonella. Thus, goals are to i) discover RBPs of phages infecting C. jejuni and Salmonella serovars using pyocins as a novel advanced tool, and ii) develop novel phage-derived therapeutics with high bactericidal activity targeted to C. jejuni and the most prevalent Salmonella serovars. Putative RBPs will be identified from phage sequences by exploring knowledge of phage receptors and similarity of RBPs among phages binding identical receptors. By creating RBP fused-pyocins, potent killing activity of retargeted pyocins will be used to demonstrate binding specificities of RBPs to C. jejuni and Salmonella. Mutational analysis will identify key amino acids responsible for RBP binding, which also will be modified to modulate the specificity of the retargeted pyocins, developing an arsenal of novel antimicrobials targeting distinct or diverse C. jejuni and Salmonella serovars. On completion of this fellowship, I will complement my veterinary-microbiology background with bioinformatics and molecular skills including cloning, expression, purification, and structural analysis of proteins, allowing me to develop novel interdisciplinary projects exploring phage-derived proteins for human benefit. I will improve my teaching, supervision and complementary skills in project management, grant writing, and establish an international network needed to cement myself as an independent researcher.;200194,8;200194,8;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;KOBENHAVNS UNIVERSITET;DK;;;;1;0;0;1;0;0 201306;705247;DINEQ;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Tracking discoursal shift in news media representation of economic inequality: developing and applying corpus linguistic and critical discourse analysis methods;2016-09-01;2018-08-31;;DINEQ explores changes in the discoursal representation of degrees of economic inequality in selected British newspapers in 1971 and 2011. It is the first applied diachronic linguistic study to combine a consideration of the socio-political history in Britain in those forty years, a comparative analysis of selected public discourses in those two years, and a semantic, grammatical and lexical study of media representations of wealth inequality. The methodological approach used for this project is primarily Corpus Linguistic, but draws also on Systemic-Functional Grammar, and adopts a broadly Critical Discourse Analytic theory of discourse. The interdisciplinary nature of this project is complemented with the expertise of the Supervisor, Prof. Michael Toolan, and the Fellow, Dr. Eva Gomez, both experts in Stylistics and Discourse Analysis. The quality of the proposed project is ensured by the commitment of the members involved and the support committed by the University of Birmingham, one of the leading universities in Europe. This innovative study aims to demonstrate that rigorous and systematic corpus-based discourse analysis can establish discursive change over time, of a kind that is so dispersed and gradual that it is imperceptible in the day-to-day newspaper-reading of the ordinary reader.;183454,8;183454,8;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;THE UNIVERSITY OF BIRMINGHAM;UK;;;;1;0;0;1;0;0 200302;691235;INAPEM;SIGNED;H2020-EU.1.3.3.;MSCA-RISE-2015;H2020;International Network on Advanced high energy Permanent Magnets;2016-01-01;2018-12-31;;"The main objective of this Marie Curie RISE action is to improve and exchange interdisciplinary knowledge of materials design by modelling, materials synthesis, characterization, and materials processing for permanent magnet development to be able to provide a critical raw free permanent magnet to the industry. Permanent magnets are indispensable for many commercial and military applications. Major commercial applications include the electric, electronic and automobile industries, communications, information technologies and automatic control engineering. Development and improvement of new technologies based on permanent magnets requires the joint effort of a multidisciplinary researcher collective, involving the expertise of participants on different disciplines including physics, chemistry, materials science and engineering. A consortium with such expertise is put together to undertake an integrative and concerted effort (via knowledge transfer) to provide the fundamental innovations and breakthroughs that are needed to fabricate/implement industrially new phases and microstructures required for the development and application of advanced permanent magnets without the use of critical materials. Results will be widely disseminated through publications, workshops, post-graduate courses to train new researchers, a dedicated webpage, and visits to companies working in the area. In that way, we will perform an important role in technology transfer between the most advanced hard and soft magnetic materials design and characterisation methods for the development of permanent magnets.";580500;580500;H2020-MSCA-RISE-2015;/MSCA-RISE;FUNDACION BCMATERIALS - BASQUE CENTRE FOR MATERIALS, APPLICATIONS AND NANOSTRUCTURES;ES;"AMEN TECHNOLOGIES;""NATIONAL CENTER FOR SCIENTIFIC RESEARCH """"DEMOKRITOS"""""";TECHNISCHE UNIVERSITAT DARMSTADT;UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA";"EL;DE;ES";;1;0;0;1;0;0 198727;671084;INSOMNIA;SIGNED;H2020-EU.1.1.;ERC-ADG-2014;H2020;Insomnia’s Negative Sequelae On Mood: from Neuroscience to Intervention in the Aged;2015-11-01;2020-10-31;;"Major depression is among the most burdening health hazards. Its prevalence is 1-3%, an additional 8-16% have clinically significant symptoms, and prognosis is poor. Unfortunately, less than 20% of the cases are detected and treatment effectiveness is moderate. The Global Consortium for Depression Prevention stresses that our best chance to combat the global burden of depression is provide preventive intervention to identified people at risk. This project targets the strongest modifiable risk factor: insomnia. With prevalence estimates up to 40%, insomnia is among the most frequent disorders in the elderly population. Meta-analysis shows that no less than 13% of people with insomnia develop depression. This extreme risk and the very high prevalence of insomnia in the ageing population, shows the urgency and promise of: (1) early identification of these 13%, (2) finding mechanisms by quantification of how they differ from insomniacs that do not develop depression with respect to brain structure and function, psychological traits, behavioural habits and environmental exposures; and (3) enrolling them in intervention protocols aimed at sleep improvement and prevention of depression. The project extends recent findings emerging from the applicant’s pioneering, unconventional and innovative approach to insomnia; the proposal that distinct subtypes exist and can be discriminated data-driven by means of multivariate trait analysis and brain imaging. Ignorance of this heterogeneity has obstructed progress in mechanistic understanding and rational treatment. In an unprecedented interdisciplinary way the project (1) identifies the insomnia subtype that develops depression; (2) profiles mechanisms involved; and (3) optimizes effectiveness of internet-supported home-applicable interventions to improve sleep and prevent depression. This approach will identify risks and mechanisms, and facilitate immediate implementation of risk-based prevention strategies and policies.";1867360,99;1867360,99;ERC-2014-ADG;/ERC-ADG;KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW;NL;;;;1;0;0;1;0;0 198185;648624;MEMOIRS;SIGNED;H2020-EU.1.1.;ERC-CoG-2014;H2020;Children of Empires and European Postmemories;2015-11-01;2020-10-31;;"MEMOIRS focuses on the intergenerational memories of the children and grandchildren of those involved in the decolonization processes of colonies held by France, Portugal and Belgium. Through interviews of this second and third generation, and a comparative analysis of the cultures influenced by the postmemory of the colonial wars and the end of empire, Europe's postcolonial heritage will be reinterrogated, and a new understanding of the contemporary continent will be developed. At the heart of the project is a desire to comprehend the effects of Europe's postimperial diversity through postmemories of colonial praxis. The project is interdisciplinary, bringing together specialists from literary and cultural studies, history, sociology and migration studies. MEMOIRS aims to maximize the impact of its findings through broad web, open-access publications and an itinerant artistic exhibit that captures multiple aspects of the representations of postmemory, and fosters a meaningful North-South dialogue.";1982475;1982475;ERC-2014-CoG;/ERC-COG;CENTRO DE ESTUDOS SOCIAIS;PT;;;;1;0;0;1;0;0 195780;659378;SPIN2D;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Spintronics with Non-Conventional 2D Materials;2015-05-18;2017-05-17;;"Since the discovery of graphene in 2004, a member of the two-dimensional (2D) materials family, the amazing properties of these materials at the single layer level have attracted an enormous attention. Thanks to the plethora of available compounds, an extremely wide richness of properties covering the full range of electrical and magnetic behaviors is expected. For spintronics, the combination of 2D layers in designed multilayer stacks can be envisaged as a way to obtain highly optimized modules that, combined altogether, will allow the realization of fully 2D advanced spintronic devices (2D spinFETs, 2D spinOLEDs, 2D MTJs for 2D memories, etc..) leading towards their ultimate miniaturization and engineering. The multi-sectorial and interdisciplinary SPIN2D project aims at investigating the potential of 2D materials for spintronics and set a first step towards the future development of a new generation of spintronic multifunctional devices based on 2D building blocks. For this purpose, in an original chemistry and physics approach, SPIN2D will investigate and tailor the potential of two 2D materials families, Transition Metal Dichalcogenides (TMDCs) and Layered Double Hydroxides (LDHs), with the scope to: develop chemically engineered fabrication and deposition protocols; unveil and build an extensive library of relevant and combinable properties; and finally, integrate, combine and tailor 2D materials in multilayer spintronics devices.";158121,6;158121,6;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;UNIVERSITAT DE VALENCIA;ES;;;;1;0;0;1;0;0 195600;658376;ERIN;CLOSED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Europe's Reception of the Irish Melodies and National Airs: Thomas Moore in Europe;2015-09-01;2017-08-31;;"'ERIN offers a network analysis, investigating the cultural articulation of national identity in 19th-century Europe as found in the musical works of Irish poet-songwriter Thomas Moore. He created two European song series, the Irish Melodies and National Airs, of global circulation; these inspired arrangements by European composers. His epic poem Lalla Rookh inspired operas and ballets. ERIN is the first systematic study of this cultural network, and innovative in considering the temporal and spatial aspects of networking. ERIN contributes to the knowledge-based economy and society through accessible research outputs designed to engage the European public: an online forum, a podcast, a radio show, an interactive online exhibit, a database, an edited book. ERIN's research foundation is the substantial Moore collection at host Queen's; a database of its and other's Moore holdings becomes a dataset to be mined for the remaining outputs. The researcher will establish a network between herself, Queen's and selected European libraries in the process of preparing the database and the online exhibition. The researcher acquires skills that enhance her intersectoral mobility within Europe by observing a carefully-chosen training programme at Queen's that will also benefit ERIN's project outcomes. This training will also prepare her for an intended media secondment. By leading ERIN, the researcher will gain project management skills and gain valuable intersectoral contacts. Through leadership, networking, and training, the researcher will be involved in knowledge transfer. She will build on her existing experience as a contributor to several significant bibliographical and historiographical projects; the MSC fellowship will enable her to assume a position of leadership in the scholarly community (or in the media) while enhancing her creativity. Queen's enjoys 'HR Excellence in Research Status' and offers the researcher a stimulating interdisciplinary research environment.'";183454,8;183454,8;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;THE QUEEN'S UNIVERSITY OF BELFAST;UK;;;;1;0;0;1;0;0 195429;657304;GlidArc;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Towards a fundamental understanding of a gliding arc discharge for the purpose of greenhouse gas conversion into value-added chemicals;2015-06-22;2017-06-21;;Global climate change due to anthropogenic greenhouse gas emissions is a growing concern. The conversion of greenhouse gases (mainly CO2, CH4) to value-added chemicals or renewable fuels is an effective strategy to reduce these emissions and an interesting process both from economic and ecological point of view. A gliding arc (GlidArc) plasma offers unique perspectives for activating inert molecules at mild conditions and allows the greenhouse gas conversion with limited energy cost. A GlidArc is, however, very complex and poorly understood. Therefore, this project intends to obtain more fundamental insight in the plasma-mechanisms of the GlidArc for greenhouse gas conversion, by means of extensive modeling, validated by experimental diagnostics. First, the chemical kinetics in the GlidArc for greenhouse gas conversion will be studied. Second, this plasma chemistry will be incorporated in a coupled magnetohydrodynamics (MHD) - kinetics model to study the spatial and temporal plasma properties. The model will be validated by experiments, to be carried out during the secondment. Furthermore, the effects of various operating parameters, such as the CH4/CO2 ratio, the discharge power and the gas flow rates, on the gas conversion, the yields of the formed products and on the energy efficiency will be analyzed, in order to predict which conditions give rise to the highest and most energy-efficient conversion. This project is very interdisciplinary, including chemistry, physics, chemical engineering, mathematics and computer modeling, with application in environmental science and sustainable chemistry. Definitely it will extend the applicant’s skills in plasma modeling to a much broader field, with new applications, and enhance his creative and innovative potential by advanced training in an international research environment.;160800;160800;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;UNIVERSITEIT ANTWERPEN;BE;;;;1;0;0;1;0;0 195675;658868;MUSIC;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2014-GF;H2020;How the brain creates Mutual Understanding during Social InteraCtion;2016-12-31;2020-07-30;;How can we understand one another? Our everyday conversations appear to revolve around our linguistic abilities. But creating mutual understanding involves more than formulating grammatically correct sentences. Recently, cognitive science has shown that mutual understanding relies on shared knowledge and beliefs, conceptual knowledge that is continuously adjusted as we interact. Yet, social neuroscience has mainly focused on how individuals respond to social stimuli without a social context. Consequently, the neural mechanism that underlies our ability to create mutual understanding with another person remains largely elusive. The proposed project addresses this interdisciplinary gap, testing the hypothesis that creating mutual understanding requires a neural mechanism that supports a continuous adjustment of conceptual knowledge. That hypothesis will be tested by sampling and interfering with neuronal activity in humans during live social interaction, at the University of California. First, I will investigate the neuronal implementation of mutual understanding through intracranial recordings from the human brain. The exquisite spatiotemporal precision of these recordings offers the unprecedented possibility to characterize how conceptual knowledge is mechanistically adjusted during social interaction. Second, I will investigate frontotemporal dementia, a neurological disorder known to disrupt access to conceptual knowledge. This unfortunate experiment of nature offers the unique opportunity to understand how progressive alteration in brain tissue and connectivity affects the ability to create mutual understanding. These studies will offer a neural- and system-level mechanism of human mutual understanding, which I will translate into testable accounts of communicative alterations in a range of neurological and psychiatric disorders, during the return phase at the Donders Institute and King’s College London.;260929,8;260929,8;H2020-MSCA-IF-2014;/MSCA-IF-GF;STICHTING KATHOLIEKE UNIVERSITEIT;NL;;;;1;0;0;1;0;0 195262;656385;ENIRIS;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Electrogenic NItrate Reduction In marine Sediments;2016-04-01;2018-04-24;;"Recently, a novel type of long, filamentous bacteria has been discovered, which are capable of guiding electrical currents over centimeter distances. These so-called “cable bacteria” were first isolated from marine sediments, and laboratory experiments demonstrate that electrons are passed on from cell to cell along the longitudinal axis of the filaments. This long-distance electron transport radically extends the physiological capacities of prokaryotes, and profoundly changes our understanding of biogeochemical transformations in marine sediments. In my PhD research, I have documented that in addition to oxygen, these sulphur oxidizing bacteria can also use nitrate as an electron acceptor. This new form of “electrogenic” nitrate reduction could have important implications for the removal of bio-available N in marine ecosystems. However, the effect of this newly described nitrate reducing process on the global nitrogen cycle, as well as the factors that ultimately control the occurrence, remain unknown. The goal of this project is to identify the end products of the electrogenic nitrate reduction and the environmental controls that regulate its occurrence. This project will hence provide new insights into the physiological abilities of micro-organisms and improve our understanding of N dynamics in marine sediments, strengthening European excellence in these fields of research. The goals of the project will be attained by combining state-of-the-art biogeochemical techniques with a novel and interdisciplinary approach based on principles traditionally applied in microbiology, electrochemistry and geophysics. This project will allow me to work on an up-to-front topic and thus to build up a unique research profile among the large number of researchers in the of nitrogen cycling.";163044,6;163044,6;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;VRIJE UNIVERSITEIT BRUSSEL;BE;STICHTING NIOZ, KONINKLIJK NEDERLANDS INSTITUUT VOOR ONDERZOEK DER ZEE;NL;;1;0;0;1;0;0 195260;656377;Transnat_farright;CLOSED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Transnational nationalism. Far-Right Nationalist Groups in East Central Europe in the 20th and 21st centuries;2015-10-01;2018-06-01;;"The project will study networks of youth far-right nationalist organizations in East Central Europe, paying particular attention to the developments in Austria, Croatia, Hungary, and Poland. Using historical and anthropological methods, the study explores the transnational dimension of nationalist organizations: the networking of ideologies and tactics. It entails a combination of archival research, interviews, and participant observation during nationalist gatherings. In proposing a historical-ethnographic study of youth far-right nationalist groups, the project aims to fill the gap in existing scholarship, resulting from the lack of interdisciplinary dialogue, negligence of a historical dimension, and macro-perspective predominance. Inspired by the transnational history approach, it foregrounds the complex – synchronic and diachronic - interactions between European nationalisms and studies agents of those exchanges, examining nationalist activists’ motivations and experiences. A combination of anthropological in-depth analysis and historical approach offers an original perspective by drawing parallels between nationalist activities against a multinational federative system, the Austro-Hungarian Empire, and the EU. It provides a critical tool for challenging unidirectional models of modernity and nationalism and for reflecting on the challenges to the European integration. The project will be undertaken at the Institute for East European History, University of Vienna, under the supervision of Prof. Philipp Ther, a leading specialist in the field of transnational history. During the secondment at the Department of Gender Studies, Central European University in Budapest, I will explore the gender dimension of nationalist activism. The fellowship will constitute a fundamental step in my academic career, enabling me to develop a new field of research and expertise and to gain skills necessary to become an independent researcher and to lead my own research group.";178156,8;178156,8;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;UNIVERSITAT WIEN;AT;;;;1;0;0;1;0;0 195394;657123;PHYSIO-POP;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Physiological and environmental controls of water and ozone fluxes in a short rotation poplar plantation: from leaf to tree to ecosystem scale.;2015-09-01;2017-08-31;;"One of the consequences of global climate changes is the altered global water availability. Among the greenhouse gases (GHGs) causing global climate changes, carbon dioxide (CO2) has received most attention. Over the last decennia the impact of rising CO2 concentrations on crops has been widely studied. The study of tropospheric ozone (O3) and its consequences on crops has not been as extensive, although O3 is a widespread and damaging air pollutant in industrialized countries. The PHYSIO-POP project fits within the search for renewable (bio-)energies, in particular the production of woody biomass energy. The project will examine the water consumption and the sensitivity to O3 pollution of a short rotation poplar plantation with fast-growing poplars (Populus spp.) for biomass production. The multidisciplinary and interdisciplinary approach followed by this PHYSIO-POP proposal aims to improve our knowledge of the impact of global climate change by studying the physiological and environmental controls of water and O3 fluxes in different short rotation poplar genotypes at all relevant biological (leaf, tree, ecosystem) and time (daily, seasonal) scales. To achieve this objective the project makes the unusual combination of plant (eco-)physiological studies at the leaf and the tree levels with model simulations at tree and ecosystem levels to improve our understanding of what happens at the whole plantation, from the leaf to the ecosystem scale over the individual tree level.";172800;172800;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;UNIVERSITEIT ANTWERPEN;BE;;;;1;0;0;1;0;0 197836;637709;GREYZONE;SIGNED;H2020-EU.1.1.;ERC-StG-2014;H2020;Illuminating the 'Grey Zone': Addressing Complex Complicity in Human Rights Violations;2015-09-01;2020-02-29;;"The grey zone of bystanders, collaborators and beneficiaries of violence escapes the scope of main Transitional Justice (TJ) institutions and poses tough questions for scholars and architects of post-conflict societies. This interdisciplinary project shifts the focus of academic and political debates by pursuing three objectives: conceptually, it departs from the dominant victim-perpetrator paradigm and theorises the many faces in the grey zone by analysing the interplay between structure and agency; normatively, it argues that no account of TJ is complete without engaging the grey zone; empirically, it tests if, in tackling the grey zone, cinematographic and literary representations can supplement typical TJ mechanisms (trials, truth commissions, lustration). Four cases are analysed: authoritarianism plus military occupation (Vichy France), apartheid (South Africa), totalitarianism (Romania 1945–1989) and military dictatorship (Argentina 1976–1983). The cases provide a variety of contexts of complicity and feature the most frequently used TJ mechanisms. They serve to a) examine the relationship between the official story emerging from state-orchestrated TJ mechanisms and artistic narratives of complicity; b) contextually distinguish disclosive from obscuring artistic representations of the grey zone; c) explore the contribution of these representations to TJ efforts by studying their effect on public debates about—and institutional responses to—the past. Working at the frontiers between political science, philosophy, history, law, literature and cinema, this pioneering project has critical and institutional impact. Critically, it discloses the limits of current TJ theory and practice by emphasising the negative political effects of ignoring general complicity in violence. Institutionally, it seeks to enrich the toolkit of scholars and practitioners by pointing to the potential use of cinema and literature in civic education aimed at deterrence and reconciliation.";1349481;1349481;ERC-2014-STG;/ERC-STG;THE UNIVERSITY OF EDINBURGH;UK;;;;1;0;0;1;0;0 193506;637579;COMPUCELL;SIGNED;H2020-EU.1.1.;ERC-StG-2014;H2020;Autonomous Cellular Computers for Diagnosis;2015-05-01;2020-04-30;;"Early diagnostics based on multiple biomarkers is key in numerous diseases, yet current technologies for multiplexed detection are complicated and expensive. Living cells detect and process various environmental signals in parallel and can self-replicate, presenting an attractive platform for scalable and affordable autonomous diagnostic devices. In this project, I will apply my expertise in synthetic biology, the rational engineering of biological systems, to build cell-based biosensors for multiplexed diagnosis using the non-pathogenic bacterium Bacillus subtilis. In a first research line, I will conceive a scalable detection machinery by engineering chimeric receptors detecting extracellular biomarkers via sensing domains derived from antibodies. In a second research line, I will implement bio-molecular computing systems operating within and across bacterial cells to perform multiplexed biomarkers analysis. I will deploy in B. subtilis biomolecular logic gates and will engineer specific cell-cell communication systems to perform distributed multicellular computation in a bacterial consortia. My project is highly interdisciplinary and is at the cross-roads of genetic engineering, structural biology, biophysics, modeling, and clinics. On foundational point of view, I will make several breakthrough contributions to synthetic biology: (i) Advancing engineering frameworks for the Gram-positive model, B. subtilis. (ii) Pushing the limits of custom-ligand detection by engineered cells (iii) Exploring the frontiers of man-made biological computers. On an applied point of view, I plan to deliver a first prototype for the urinary diagnostic of diabetic nephropathy, a major complication of diabetes. Because of the modular design principles applied, my sensing platform will be reusable to diagnose other pathologies as well as for applications requiring custom-detection and bio-molecular computation like targeted therapy, drug delivery, or environmental monitoring.";1500000;1500000;ERC-2014-STG;/ERC-STG;INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE;FR;;;;1;0;0;1;0;0 215101;792855;IRS-CESC;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;THE ROLE OF THE INFORMAL RECYCLING SECTOR ON CLOSING THE LOOPS TO SUSTAINABLE CITIES;2018-06-01;2020-07-07;;"It is widely recognized that waste recycling can reduce both natural resource scarcity and negative environmental impacts of increasing trash production. Expanding the waste recycling is a key to construct Circular Economy (CE) approaches, contributing significantly to the global climate-change mitigation effort, at both local and national scales. Integrated Sustainable Waste Management (ISWM), of which waste recycling encompasses one part, is essential on a global scale. Innovative, low-cost methods of waste recycling was developed by vulnerable and marginalized waste pickers , which have led to the creation of an informal waste recycling sector (IRS) which are currently being used in Brazil and others LMIC, and have the potential to be more widely deployed. The IRS has developed work procedures that diverge from those deployed in EU recycling, setting a social technology (ST). This IRS ST is beneficial to ISWM, as it diminishes overall costs and amplifies quantities recovered, besides providing income to a poor, jobless population. This research will validate the possible gains from disseminating the Brazilian IRS ST to other LMIC countries as an ISWM policy and in support to CE strategies, which will involve a comparison of the Brazilian IRS with the EU recycling model; as such, it will consider how to make social and ecological value visible in value-analysis methods. The research will be carried on by the ER, whose ten years’ research has driven to a crossing point of economics, engineering, and environmental disciplines, the same scope of University of Leeds’ Cities theme. These will enable the ER to acquire the new skills and experience to achieve a position of an independent and professionally mature researcher in the field of CE at international level, leading interdisciplinary action-research groups to support international organizations on initiatives to more sustainable and inclusive cities, in direction to a Green Economy.";146591,1;146591,1;H2020-MSCA-IF-2017;/MSCA-IF-EF-CAR;UNIVERSITY OF LEEDS;UK;;;;1;0;0;1;0;0 215453;796499;REDUCTeeth;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Evolution of cell mechanisms underlying human dental reduction in Europe;2018-10-01;2020-09-30;;The human skeleton has continued to evolve over the past 40,000 years in Europe, long after the emergence of our species. During this period, major social, technological and demographic changes occurred as a mobile hunter-gatherer lifestyle gave way to sedentary farming villages, and then cities. This was accompanied by biological changes to our skeletons, which are retained into the present day. One of the most striking changes is the reduced size of our teeth and jaws. This dental reduction contributes to dental crowding for modern day Europeans, which requires extensive orthodontic treatment with a significant global socio-economic cost. Despite 50 years of academic debate amongst anthropologists about the hypothesised causes underlying dental reduction, a consensus has still to be reached. Yet, we know nothing about the cell mechanisms that facilitated the reduced size of our teeth and jaws. The goal in this project is to develop an original, interdisciplinary and holistic approach that combines dental and bone analysis at three structural levels, to identify and describe the micro-evolutionary cell mechanisms that led to the reduction of modern human teeth and jaws in Europe. Combining cutting-edge histological and microtomographic techniques, I will examine molars and jaws from prehistorical, medieval and modern samples, spanning our most recent evolution from ~38,000 years ago to the present day. Using these cell mechanisms, I will re-evaluate the existing hypothesised causes of dental reduction. This project will provide a unique biological insight that will help to resolve a long-standing debate, and reshape our understanding of dental reduction during recent human evolution. Results will be of interest to anthropologists, biologists, and the general public. My project can also contribute new information for clinical orthodontic treatment. Results will be published in high-impact scientific journals and presented at international conferences.;183454,8;183454,8;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;UNIVERSITY OF KENT;UK;;;;1;0;0;1;0;0 215709;799153;Stories;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Inside/Out: using storytelling to understand the politics of exclusion in Europe and South Africa;2018-09-01;2020-09-30;;Contemporary political narratives in the UK and South Africa are explicitly orientated around ideas about who does, and does not, belong. The UK and South Africa, while different, share trends towards inequality and the othering of migrants as responsible for social problems. Both inside and outside groups express a powerful sense of alienation and hopelessness. This fellowship will use storytelling to generate new bottom-up narratives to challenge dominant top down discursive politics of exclusion. Personal stories will be created by research with people from different communities that are typically positioned as being against one another. These creative, story-based research methods will catalyse public dialogues on the possibilities for new, more inclusive political narratives to build understanding and trust between groups. The fellowship will enable the researcher to strengthen the interdisciplinary basis of her research, by bringing together the disciplines of politics, sociology and psychology. She will also learn from the expertise and networks of Professor Heaven Crawley and colleagues at the Centre for Trust, Peace and Social Relations (CTPSR) at Coventry University working on public and political migration narratives in the UK and Europe. This will lead to future research collaborations and career development opportunities at CTPSR. CTPSR will, in turn, benefit from the researcher’s in-depth expertise in the use of storytelling to build dialogue between communities and her knowledge of the ways in which narratives of migration, inclusion and exclusion have developed in South Africa and from her experience globally.;195454,8;195454,8;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;COVENTRY UNIVERSITY;UK;;;;1;0;0;1;0;0 214898;787719;SurvCom;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Surveilling Communities: Public office holders and popular control in Southern Europe (13th-15th century);2018-10-01;2020-09-30;;"While officers’ accountability appears modern, past societies had their own systems for local communities to engage in politics and even in procedures to control public office holders. Most European regions experienced a major socio-political transformation in the 13th century, with significant expansions in the number and range of officers nominated by central powers (e.g. the king) to represent them, govern and execute justice. This increase was accompanied by varied attempts to implement accountability procedures in order to evaluate whether officers were executing their duties properly. The overall objective of SurvCom is to analyse the participation of local communities in holding public officers accountable in late medieval southern Europe. This analysis will answer three fundamental questions that correspond to the specific objectives of the project. 1. Were local medieval communities effectively empowered by their participation in officers’ accountability? 2. What was their resulting input in the designing and shaping of the incipient states? 3. How did their engagement in controlling office-holders relate to the longue durée shift in the relationship between governors and governed in the transition from feudal to absolutist societies? SurvCom focuses on a comparative analysis of territories from Castile, the south of France and the north of Italy and draws on interdisciplinary perspectives. Firstly, it uses Surveillance Studies, an emerging field analysing how surveillance practices work and their role in shaping current and past societies. Secondly, SurvCom uses Gender Studies to address informal relations and provide a means to integrate women’s agency in the interaction with officers and central powers. SurvCom will bring new perspectives to debates about statebuilding from below, corruption studies and officers’ accountability and will transfer knowledge regarding historical experiences on governance and surveillance from below (sousveillance).";195454,8;195454,8;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;UNIVERSITY COLLEGE LONDON;UK;;;;1;0;0;1;0;0 218541;818965;FAWORIT 2018-2019;SIGNED;H2020-EU.1.3.5.;MSCA-NIGHT-2018;H2020;Fascinating World of Researchers in the Age of Technology – Cultural Heritage & the New Generation of Innovators;2018-05-01;2019-12-31;;"The main objective of our proposal is to present researchers from several aspects in order to get them closer to the general public and to encourage the youth – with a special focus on girls – to embark on scientific careers. We will apply a mission-oriented, impact-focused approach in our project in which interdisciplinary challenges, innovative solutions, (young) researchers, their work and hobbies will be presented in an interactive, educating and entertaining way to stimulate the interest of citizens towards R&I and to bring it closer to their expectations and concerns. A special attention will be given to the role of R&I in discovery, preservation and demonstration of cultural heritage; the bridges between STEM and cultural heritage will be demonstrated. As the consortium and the cooperating partners represent well the relationship of the knowledge triangle, the involvement of many different actors across various disciplines and sectors will achieve a high impact and make researchers and innovators' work familiar to various age groups. Our main target group is students of age 6-26, but we aim to address all age groups – siblings, parents & grandparents – with attractive programmes. The target audience can thus discover that being a researcher is cool and creative and not only researchers, but young innovators are also amongst us. Our objective is to have at least 30000 visitors on our 24 venues on the two-day event, but a multiple of that number (at least 1000000) will see, hear or read about the NIGHT. Our venues cover the whole country. We expect at least doubling them by organisations joining the NIGHT – the most important science communication event in Hungary – as the result of the awareness raising campaign. We intend to raise awareness of the European engagement in R&I through the participation of H2020 projects with a special focus on MSCAs. In the European Corners and at each venue related programmes of the European Union will be visible.";238375;238375;H2020-MSCA-NIGHT-2018;/CSA;REGIONALIS INFORMACIOS ES FEJLESZTO TUDASKOZPONT KORLATOLT FELELOSSEGU TARSASAG;HU;"NOK A TUDOMANYBAN EGYESULET;TUDOMANYOS ISMERETTERJESZTO TARSULAT;BAY ZOLTAN ALKALMAZOTT KUTATASI KOZHASZNU NONPROFIT KFT.;HETFA KUTATOINTEZET KFT";HU;;1;0;0;1;0;0 215431;796220;MIONI?O;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Resolving the debate on a permanent El Ni?o-like state in the late Miocene: establishing equatorial Pacific conditions, driving forces and global impacts.;2019-04-23;2021-04-22;;"A key dispute in palaeoclimate research is whether or not a permanent El Ni?o-like state, with warm waters spreading across the equatorial Pacific, existed during the late Miocene. Late Miocene climate was similar to the 4°C warming predicted for 2100 by the IPCC. As today’s El Ni?o causes global climate anomalies, a permanent El Ni?o-like state in the past may have had serious, global consequences, such as widespread aridity. MIONI?O will test the existence of a late Miocene permanent El Ni?o-like state using geochemical microfossil records from recently recovered Western Pacific Warm Pool (WPWP) sediments and earth system modelling to assess equatorial Pacific conditions, their driving forces and global impacts. MIONI?O is timely, only being possible since the recovery of crucial WPWP samples in late 2016. MIONI?O is also original and novel, presenting a new template for solving complicated climate questions using a new, robust stratigraphy and an interdisciplinary approach. UCL Earth Sciences is the ideal location to pursue state-of-the-art research in palaeoceanography and stratigraphy. Combining my existing expertise with key specialist knowledge from UCL researchers will equip me with the required skills to successfully complete MIONI?O. I can hone my research vision and gain transferable skills to help me achieve my ultimate career goal of an academic research position. MIONI?O will advance past and future climate change research. Resolving the debate on permanent El Ni?o-like conditions in the late Miocene will discern whether warm El Ni?o events, as occurred in 2015/2016, become more frequent or evolve into a new mean state. Assessing causal links between permanent El Ni?o-like conditions and increased continental aridity will improve the future climate models that underpin European climate mitigation and adaptation strategies. MIONI?O can further help us understand the true societal impact of more frequent or even permanent El Ni?o-like conditions.";183454,8;183454,8;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;UNIVERSITY COLLEGE LONDON;UK;;;;1;0;0;1;0;0 215393;795904;EvISC;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Infection of the human intestine by enteroviruses: A CRISPR-based screening approach;2019-01-01;2020-12-31;;"Enterovirus infections are of public health concern as globally millions of people become infected each year. Enteroviruses (HEV) are an assemblage of highly diverse positive-stranded RNA viruses that belong to the Picornaviridae family. Four out of the 13 known enterovirus species are human pathogens, with poliovirus being the most prominent member. The entry point for these viruses is the gastrointestinal or the respiratory tract from where they can spread to other organs and cause severe pathologies. Vaccines exist only against polio and no therapies are currently available against any HEV. Thus, there is a great need for new antivirals. I aim to identify host factors crucial for the HEV life cycle by performing a whole genome CRISPR loss-of-function screen in primary cultures of human intestinal epithelial cells. Importantly, the lytic nature of HEVs will allow a straightforward selection of cells that survive virus infection upon small guide RNA-mediated deletion of host genes that support HEV infection. This interdisciplinary project demands expertise both in stem cell, enterovirus biology and host-pathogen interaction, which is provided by the Jensen lab (host), the Tapparel lab (partner) and myself, respectively. Through access to intestinal stem cells and organoids from various donors and multiple HEVs I have the unique possibility to dissect host-enterovirus interactions by taking host and virus variations into account. By integrating this data, I will be able to dissect tropism both from a host and a pathogen perspective, and identify host factors that are necessary for HEV infection. This knowledge will contribute to the discovery of novel drug targets for broad-spectrum therapies against HEV infections and moreover provide me with the unique opportunity to move forward in academia and establish my own research group.";200194,8;200194,8;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;KOBENHAVNS UNIVERSITET;DK;;;;1;0;0;1;0;0 215499;797002;SKRDC;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Architecture as a Cross-Cultural Exchange:The Shinkenchiku Residential Design Competition, 1965-2017;2018-09-01;2020-07-31;;To open up new lines of inquiry for the writing of architecture history currently caught up in ‘static’ chronological periods, geographic preferences, heroic figures, aesthetic styles, and fixed gender categories, it is necessary to introduce an entirely new analytical research methodology to the field of architecture. This project investigates the possibilities of such alternative approach by organizing history around complex cross-cultural exchanges, or “contact zones”, between different architecture cultures. To elucidate the potentials of such social spaces ‘where different cultures meet and inform each other’, I focus on an unprecedented example in architecture culture where “East” and “West” meet: The Shinkenchiku Residential Design Competition (SKRDC). SKRDC is an international housing idea competition organized by the Japanese architecture magazine Shinkenchiku since 1965. Through not only studying the competition briefs of the past 52 years, the characteristics of the winning entries and multiple honourable mentions and the judges’ final remarks, but also the difference in nuance between the Japanese and English debates resulting from the actual design proposals as well as the wider ‘aftereffects’ disseminating into both Japanese as well as English literature, I trace the reciprocal transfer of architectural knowledge and how that affected larger local and international architectural debates. While the SKRDC here serves as a qualitative case study to develop and test my analytical research method, the larger aim of this study is to construct a new historical narrative. By applying the analytical model to different architectural contact zones around the globe, I foresee to contribute to the rewriting of the history of modern architecture into a more inclusive and unbiased “cross history”, which is non-static and interdisciplinary in character and includes hitherto underrepresented aspects such gender dimensions.;177598,81;177598,8;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH;CH;TECHNISCHE UNIVERSITEIT DELFT;NL;;1;0;0;1;0;0 215417;796086;FIRE;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Fighting Insurgency, Ruining the Environment: towards an understanding of the causal relationship between conflict and forest fires;2018-10-01;2020-09-30;;"Despite the growing interest in the relationship between environmental degradation and political conflict, most discussions take the direction of causality for granted and try to understand whether or the extent to which environmental factors such as climate change-related drought lead or contribute to violent conflict. The aim of this project is to reverse the causality and look into how conflicts contribute to environmental degradation. It will do this by focusing on forest fires in the Middle East through a detailed study of the cases of Turkey, Syria and Israel. The questions that will be addressed in this context are: (1) Is there a positive correlation between inter- and intra-state conflict and forest fires? (2) How do conflicts affect ecosystems and biodiversity as well as the lives of inhabitants? (3) How are forest fires used discursively by conflicting groups? The proposed project is going to make a significant contribution to the existing literature in five ways: (1) It will explore whether actors deliberately damage the environment to gain the upperhand in a conflict; (2) it will focus on an underexplored aspect of the environment-conflict nexus, forest fires; (3) it will carry out fieldwork in three “non-European” cases which have spillover effects on European societies; (4) it will introduce novel techniques to the study of this problem, notably Geographical Information System (GIS) and digital Remote Sensing (RS); (5) it will combine “hard data” with qualitative analysis obtained through critical discourse analysis, elite interviews, and political ethnography to understand the political, economic and cultural dimensions of the environment-conflict relationship, thereby straddling the lines between natural and social sciences in a truly interdisciplinary spirit.";185857,2;185857,2;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;LUNDS UNIVERSITET;SE;;;;1;0;0;1;0;0 215778;800046;NeuroPred;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Identification of different neuro-cognitive mechanisms of prediction in language comprehension;2019-04-01;2022-03-31;;Predictions were recently proposed to be the core mechanism organizing brain functioning at all levels and in all domains. However, in contrast, within language comprehension, evidence for predictions has not been ubiquitous across participants, tasks, and materials. In my earlier research I showed that this discrepancy can be reconciled by positing the existence of at least two different neurocognitive mechanisms of prediction: active prediction that is restricted to highly informative contexts and to speakers who can rapidly exploit that informativity, and passive prediction, which is part-and-parcel of language comprehension. The objective of this project is to better understand the different mechanisms involved at the cognitive and at the neural level. I will be trained in 3 specialized techniques: Event-Related Optical Signal, eye-tracking, and magnetoencephalography, as well as new data-analysis methods. This training will enable me to establish, for both types of prediction, the time-course and associated ERP-components, underlying brain structures, their behavioural markers during free reading of texts, and patterns of connectivity and causal exchange of information between involved brain areas. An important novelty lies in the materials used in the project: fully naturalistic stories parametrized using recurrent neural networks. NeuroPred brings together two excellent laboratories: Prof. Kara Federmeier, a pioneer and one of the leading researchers in studying prediction in language comprehension, at the University of Illinois at Urbana-Champaign, and Prof. Peter Hagoort at the Donders Center for Brain, Cognition and Behaviour, a renowned expert in the neurocognition of language. The research bridges psycholinguistics, cognitive neuroscience and computer science. Thanks to this interdisciplinary approach, NeuroPred will provide me with excellent 'training through research' and enable me to transfer newly obtained skills back to the EU.;260929,8;260929,8;H2020-MSCA-IF-2017;/MSCA-IF-GF;STICHTING KATHOLIEKE UNIVERSITEIT;NL;;;;1;0;0;1;0;0 216221;788405;EPICut;SIGNED;H2020-EU.1.1.;ERC-2017-ADG;H2020;Molecular mechanisms, evolutionary impacts and applications of prokaryotic epigenetic-targeted immune systems;2018-08-01;2023-07-31;;"Interactions between bacteria and their viruses (bacteriophages) have led to the evolution of a wide range of bacterial mechanisms to resist viral infection. The exploitation of such systems has produced true revolutions in biotechnology; firstly, the restriction-modification (RM) enzymes for genetic engineering, and secondly, CRISPR-Cas9 for gene editing. This project aims to unravel the mechanisms and consequences of prokaryotic immune systems that target covalently-modified DNA, such as base methylation, hydroxymethylation and glucosylation. Very little is known about these Type IV restriction enzymes at a mechanistic level, or about their importance to the coevolution of prokaryotic-phage communities. I propose a unique interdisciplinary approach that combines biophysical and single-molecule analysis of enzyme function, nucleoprotein structure determination, prokaryotic evolutionary ecology, and epigenome sequencing, to link the molecular mechanisms of prokaryotic defence to individual, population and community-level phenotypes. This knowledge is vital to a full understanding of how bacterial immunity influences horizontal gene transfer, including the spread of virulence or antimicrobial resistance. In addition, a deeper analysis of enzyme function will support our reengineering of these systems to produce improved restriction enzyme tools for the mapping of eukaryotic epigenetics markers.";2196413,75;2196413,75;ERC-2017-ADG;/ERC-ADG;UNIVERSITY OF BRISTOL;UK;THE UNIVERSITY OF EXETER;UK;;1;0;0;1;0;0 216082;776665;EdiCitNet;SIGNED;"H2020-EU.3.5.2.1.;H2020-EU.3.5.2.3.;H2020-EU.3.5.1.2.;H2020-EU.3.5.1.3.;H2020-EU.3.5.2.2.";SCC-02-2016-2017;H2020;Edible Cities NetworkIntegrating Edible City Solutions for social resilient and sustainably productive cities;2018-09-01;2023-08-31;;"The systemic use of urban landscapes for food production is a major step towards more sustainable, liveable and healthier cities. A multitude of initiatives around the World, however fragmented, are prospering, forming a global movement of Edible Cities. Their products, activities and services – the Edible City Solutions (ECS) - empower local communities to overcome social problems by their inclusive and participatory dynamics and to create new green businesses and jobs, and thereby generating local economic growth and fostering social cohesion. EdiCitNet will leverage the substantial benefits that ECS effect today at local level and catalyse their replication EU- and world-wide by launching a fully open and participatory network of cities, empowering their inhabitants by a common methodology a) to systematically explore the wealth and diversity of existing ECS, b) to adapt, plan and implement successfully proven ECS in their specific urban context. To make this happen, EdiCitNet will close knowledge gaps in the effective implementation of ECS and their transformation into sustainable, innovative business models. This new insight will feed into a openly shared and globally accessible knowledge base and methodology to enable sustainable and evidence-based integration of ECS into the long-term urban planning of cities covering a large spectrum of urban, climatic, social, environmental and cultural contexts. 5 Front Runner Cities (FRC), supported by a highly interdisciplinary consortium of city authorities, SME, NGOs and academia, will demonstrate their unique experience with own Living Labs and transfer their knowledge to 7 dedicated Follower Cities (FC), determined to replicate ECS for the benefit of their inhabitants. The carefully selected group of FRC and FC allows to study and monitor implementation in large variety of environments and also ensures truly global outreach with city partners based in Central America, Africa and East Asia";11921624,75;11254912,88;H2020-SCC-NBS-2stage-2017;/IA;HUMBOLDT-UNIVERSITAET ZU BERLIN;DE;"UNIVERSITY OF BRIGHTON;FUNDACIO INSTITUT CATALA DE RECERCA DE L'AIGUA;NIBIO - NORSK INSTITUTT FOR BIOOKONOMI;ROYAL MELBOURNE INSTITUTE OF TECHNOLOGY SPAIN SL;STADT ANDERNACH;HIDROLAB, PROJEKTIRANJE IN INZENIRING DOO;OSLO KOMMUNE;SENATSVERWALTUNG FUER STADTENTWICKLUNG UND WOHNEN;UNIVERSITAT DE GIRONA;UNITE TECHNIQUE DU SEMIDE GEIE;COMMUNE DE CARTHAGE;TRANSITION OSTSTEIERMARK - GEMEINSCHAFTEN NACHHALTIG GESTALTEN;Ajuntament de Sant Feliu de llobregat;LETCHWORTH GARDEN CITY HERITAGE FOUNDATION;DEUTSCHER DACHGARTNER VERBAND E.V.;VILLE DE LOME;OBCINA SEMPETER-VRTOJBA;ASSOCIATION TUNISIENNE DE DEVELOPPEMENT DURABLE: LA RECHERCHE EN ACTION;OSLOMET - STORBYUNIVERSITETET;TECHNISCHE UNIVERSITAT BERLIN;INTERNATIONALE BAUAUSSTELLUNG HEIDELBERG GMBH;GALLIS HELENE;BRIGHTON & HOVE FOOD PARTNERSHIP LTD;UNIVERSITAET FUER BODENKULTUR WIEN;GEMEENTE ROTTERDAM;TERRA CONCORDIA GEMEINNUTZIGE GMBH;MINISTERIO DE EDUCACION Y CULTURA;NOLDE ERWIN;WAGENINGEN UNIVERSITY;UNIVERZA V LJUBLJANI;FUNDACIO SOLIDARITAT UB;PEKING UNIVERSITY";"UK;ES;NO;DE;SI;FR;TN;AT;TG;NL;UY;CN";;1;0;0;1;0;0 215344;795309;IDCLOTHING;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Clothing, fashion and nation building in the Land of Israel;2019-01-14;2021-01-13;;'Culture is central to nation building, but clothing, fashion and aesthetic perceptions are often overlooked in this context. Taking 'Eretz Israel' (the 'Land of Israel') as a case study, this project argues that investigating these cultural practices brings to the fore the agency of migrant groups and adds a personal dimension to the history of nation building. Focusing on the period from the 1880s when large-scale migration began, until the foundation of the Israeli state in 1948, it investigates how Eastern European and German Jewish immigrants expressed social, cultural and political belonging through clothing and to what extent they were able to enforce their ideologies in the course of nation building. It asks to what extent the immigrants influenced each other in developing a specific mode of dress, and how they referenced the socio-cultural and political practices of countries of origin, as well as the clothing of Arab people and the Ottoman and British occupying authorities. With an unprecedented focus on gender and visual materials, the project examines how clothing became fashion and to what extent a consensual mode of dress emerged within a heterogeneous migrant society. Drawing from archival collections of 15 archives in Israel, Poland and England, and 6 Israeli, German, American and Russian databases, the project analyses private and public photographs and posters, and contextualises them against an assessment of written material and oral history interviews. Through highly interdisciplinary training, the project develops a new methodology that integrates approaches from fashion history and visual culture into the history of nation building to shed light on the processes of negotiation and power struggles on the micro level of a community. In times of mass migration, economic exploitation and global mobility the project contributes to an understanding of aesthetic perceptions, dress and beauty ideals as an expression of power, integration and exclusion.';170509,2;170509,2;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;THE HEBREW UNIVERSITY OF JERUSALEM;IL;;;;1;0;0;1;0;0 215275;794627;AlgSignSen;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;The Algebraic Geometry of Chemical Reaction Networks: Structural conditions for uniquely determined Sign-sensitivities.;2019-03-01;2021-02-28;;"Chemical Reaction Network Theory (CRNT) focuses on determining the dynamical behavior of a (chemical) reaction network from its structural properties. To this end, different approaches within different areas of Mathematics are employed. We use here an algebraic geometric approach: The evolution of the concentrations of the species is modelled by a system of ordinary differential equations (ODEs). Under mass-action kinetics, the ODEs are polynomial, and thus the relevant steady states are the nonnegative solutions of a system of polynomial equations, which can be regarded as the nonnegative part of an algebraic variety (involving unknown parameters). This project addresses the problem of determining sign-sensitivities, that is, whether the concentration of one species at steady state increases/decreases after a perturbation is applied to the system. In particular, we wonder under which structural conditions are sign-sensitivities independent of the parameters of the system and of the original steady state. The novelty of this proposal resides in that we do not aim at developing algorithms for finding sign-sensitivities, but at obtaining theorems that explain why and when some sign-sensitivities are uniquely determined. The results will allow potential users to manipulate large networks without knowing all the parameters and overcomes the uncertainty of current algorithms arising from having to choose parameter values. I will use my background in Algebraic Geometry to begin a research career in Applied Algebraic Geometry. I will acquire new competences in interdisciplinary research and intersectorial transference of science, and improve my skills in communication and project management. I will work under the mentorship of Elisenda Feliu, in the group Mathematics of Reaction Networks. Due to their resources, experience and knowledge, they represent the perfect environment for the transition from Pure to Applied Mathematics, and in particular for my training in CRNT.";200194,8;200194,8;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;KOBENHAVNS UNIVERSITET;DK;;;;1;0;0;1;0;0 215304;794950;MoCRIV;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Modeling critical reliability issues in VLSI technologies beyond 2020;2018-08-22;2020-08-21;;"This proposal presents an interdisciplinary, forward looking, training-by-research plan in the field of physical reliability modeling of emerging transistors and materials beyond 2020. Its main goal is development and validation of a simulation framework which self-consistently considers the main reliability phenomena including bias temperature instability, hot-carrier degradation, and self-heating. These effects were suggested to be the response of interface and oxide defects/precursors which can be activated by different driving forces determined by device operating conditions and specifics of the device topology. Thus, the core of this project will be put on a detailed microscopic description of the properties of defects/precursors, which will be studied experimentally and theoretically. Within this defect-centric paradigm we will address reliability issues in devices with emerging architectures, i.e. fin and nanowire transistors, high-k gate dielectrics, and high mobility channel materials such as SiGe, Ge, and III-V alloys. The unifying model building on the microscopic defect properties will be validated over a wide range of device bias conditions. We will capture the parasitic effect of self-heating which has a strong impact on the energetic distribution of hot carriers and hence on hot-carrier degradation. Special attention will be paid to time-dependent variability of device characteristics which is a response of nanoscale devices on activation/deactivation of individual defects. Knowledge acquired within this project will be valuable for applied and fundamental physics, material science, computational chemistry, electrical engineering, VLSI technology, and circuit design. The research and training activities will enhance applicant’s future career by broadening his professional skills and expertise, expose him to industrial requirements, and open new perspectives for future collaboration with industry.";172800;172800;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;INTERUNIVERSITAIR MICRO-ELECTRONICA CENTRUM;BE;;;;1;0;0;1;0;0 212057;755753;CCLAD;SIGNED;H2020-EU.1.1.;ERC-2017-STG;H2020;The Politics of Climate Change Loss and Damage;2018-05-01;2023-04-30;;"The way in which normative principles (“norms”) matter in world politics is now a key area of international relations research. Yet we have limited understanding of why some norms emerge and gain traction globally whereas others do not. The politics of loss and damage related to climate change offers a paradigm case for studying the emergence of - and contestation over - norms, specifically justice norms. The parties to the UN Framework Convention on Climate Change (UNFCCC) have recently acknowledged that there is an urgent need to address the inevitable, irreversible consequences of climate change. Yet within this highly contested policy area - which includes work on disaster risk reduction; non-economic losses (e.g. loss of sovereignty); finance and climate-related migration - there is little consensus about what loss and damage policy means or what it requires of the global community, of states and of the (current and future) victims of climate change. Relying on an interdisciplinary theoretical approach and an ethnographic methodology that traverses scales of governance, my project - The Politics of Climate Change Loss and Damage (CCLAD) - will elucidate the conditions under which a norm is likely to become hegemonic, influential, contested or reversed by introducing a new understanding of the fluid nature of norm-content. I argue that norms are partly constituted through the practices of policy-making and implementation at the international and national level. The research will examine the micro-politics of the international negotiations and implementation of loss and damage policy and also involves cross-national comparative research on domestic loss and damage policy practices. Bringing these two streams of work together will allow me to show how and why policy practices shape the evolution of climate justice norms. CCLAD will also make an important methodological contribution through the development of political ethnography and “practice-tracing” methods.";1471530;1471530;ERC-2017-STG;/ERC-STG;UNIVERSITY COLLEGE LONDON;UK;;;;1;0;0;1;0;0 211880;765042;ViBrANT;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2017;H2020;VIral and BacteRial Adhesin Network Training;2018-01-01;2021-12-31;;"ViBrANT (VIral and BacteRial Adhesin Network Training) brings together an interdisciplinary team of world-leading European infection researchers, focused on a cutting-edge translational research project to understand host-pathogen adhesion and to develop novel, highly-specific nanoscale diagnostics to improve patient care. Host-pathogen interactions are the basis for infectious diseases, but the research methodologies needed to unravel these interactions and translate them into viable diagnostic tools are complex and change rapidly. ViBrANT will deliver high-impact fundamental and translational science and in so doing will educate 15 ESRs. We have the demonstrated track-record and infrastructure to train ESRs in highly innovative methodologies, including structural biology, proteomics, genetics, comparative genomics, lab-on-a-chip technology and the development of state of the art diagnostics in the field of infectious diseases. ViBrANT will investigate the poorly understood structure-function relationships between pathogen adhesins and hosts in an integrative manner. The ESRs in the project will have extensive intersectoral mobility across 7 EU/EEA countries, accessing the best complementary skills in each of the hosting institutions. ViBrANT comprises 8 leading universities, 1 public research institution and 6 companies (from SME to multinational). The project will impact adhesion biology in general; the detection of multi-antibiotic resistant human pathogens will have priority. The ESRs will acquire the necessary skills to translate fundamental research into technologies that will have a strong positive effect on the care of patients with infectious diseases. ViBrANT science will be high-impact and deliver 15 highly-trained innovative researchers and a long-lasting inter-sectoral collaborative network. Together, we will continue to develop fundamental research and translate it for the socio-economic benefit of Europe.";3925220,4;3925220,4;H2020-MSCA-ITN-2017;/MSCA-ITN-ETN;UNIVERSITY OF LEEDS;UK;"UNIVERSIDADE DO MINHO;HELSINGIN YLIOPISTO;LUNDS UNIVERSITET;CENTITVC - CENTRO DE NANOTECNOLOGIA E MATERIAIS TECNICOS FUNCIONAIS E INTELIGENTES ASSOCIACAO;BIOMERIEUX SA;INSTITUT PASTEUR;JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN;UNIVERSITETET I OSLO;UNIVERSITY OF HULL;EBERHARD KARLS UNIVERSITAET TUEBINGEN";"PT;FI;SE;FR;DE;NO;UK";;1;0;0;1;0;0 211713;725840;PAINTBOX;SIGNED;H2020-EU.1.1.;ERC-2016-COG;H2020;Pancreatic islet dysfunction and type 2 diabetes – beyond the genome;2017-10-01;2022-09-30;;"The prevalence of type 2 diabetes (T2D) is rapidly increasing worldwide and despite great efforts to prevent and cure the disease, the increase persist. There is an urgent need to develop innovative and effective prevention and treatment strategies for T2D. Recent genome-wide association studies were expected to uncover disease-causing mechanisms in common metabolic disorders. Surprisingly, the identified genetic variants only explain a small proportion of the estimated heritability of T2D. Novel studies, going beyond the genome, are therefore needed to identify key mechanisms causing T2D. These studies should focus on pancreatic islets, the tissue of primary pathogenetic importance for diabetes. Also, mechanisms that allow environmental factors to come into play are likely to be important. Epigenetics fulfill such criteria, and our previous work has pioneered epigenetic discoveries in T2D. PAINTBOX is a multidisciplinary research program through which I will combine advanced sequencing technologies and novel epigenetic methods with mathematical models and clinical medicine to develop new prediction and treatment strategies for T2D. Innovative techniques and access to some of the world´s best patient cohorts permit me to address the role of epigenetics in development of T2D in new ways. The annotation of these discoveries will be done using genome-wide epigenomic and targeted gene-editing tools together with mathematics, whereas the translation of those findings will be achieved using powerful prospective cohorts for T2D and clinical studies. PAINTBOX capitalizes on the largest existing human islet cohort and large prospective cohorts, and expertise that I have built-up over the past twenty years, but also exploits novel epi-genomic and gene-editing technologies that have not previously been used for T2D. I expect this novel interdisciplinary project to generate groundbreaking results that opens up new horizons for prediction, prevention and treatment of T2D.";1969445;1969445;ERC-2016-COG;/ERC-COG;LUNDS UNIVERSITET;SE;;;;1;0;0;1;0;0 211426;763594;CSRC;SIGNED;H2020-EU.4.a.;WIDESPREAD-04-2017;H2020;Center for STEAM Education Research, Science Communication and Innovation;2017-09-01;2018-08-31;;"Establish in Cyprus a Science and Research Center to: a. Undertake competitive interdisciplinary research of excellence for the development of innovative tools and exhibits for Science, Technology, Engineering, Art and Mathematics (STEAM) Education and Science Communication. b. Promote science literacy and capacity building through informal STEAM Education using interactive Science Technology and Engineering (STE) exhibits, demonstrations and contact with scientists. c. Contribute towards a Responsible Research and Innovation (RRI) culture through open schooling, Science Communication and outreach activities. d. Provide teacher professional training for integrating in-house developed ICT tools in formal STEAM Education and promote endorsement of new STEAM educational strategies and curricula. e. Serve as a hub to communicate and disseminate to public and industry innovative technology research outcomes and evidence-based practice to policy makers and provide a platform for entrepreneurship for supporting public engagement in entrepreneurship and start-up companies. Research excellence and innovation will be attained through “Teaming” collaborations, exchange visits and networking with EU Centers of Excellence in ICT research and STEAM Education, and with renowned Science Centers and the public and private universities of Cyprus. The Center will work with academics, expert in various fields, and employ staff and researchers with expertise in Computer Science and ICT, STEAM Education and Science Communication. An entrepreneurship unit hosting a prototyping platform for innovation will be used for dissemination of research outcomes, advising innovative patents, promoting start-ups and establishing links with the industry. The Center will be a unique landmark with a positive long term impact on innovation, Cyprus economic growth and Education, in accordance with “Europe 2020”, and adhering to the objectives of the Teaming Phase I Call.";399750;399750;H2020-WIDESPREAD-04-2017-TeamingPhase1;/CSA;UNIVERSITY OF CYPRUS;CY;"GRANTXPERT CONSULTING LIMITED;EUROPEAN UNIVERSITY CYPRUS;EDEX - EDUCATIONAL EXCELLENCE CORPORATION LIMITED;TECHNOLOGIKO PANEPISTIMIO KYPROU;NEAPOLIS UNIVERSITY;UCLAN CYPRUS LIMITED;ETABLISSEMENT PUBLIC DU PALAIS DE LA DECOUVERTE ET DE LA CITE DES SCIENCES ET DE L'INDUSTRIE;FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS;KOBENHAVNS UNIVERSITET;Fondazione IDIS-Citt? della Scienza;LEIBNIZ-INSTITUT FUR DIE PADAGOGIKDER NATURWISSENSCHAFTEN UND MATHEMATIK AN DER UNIVERSITAT KIEL;ANOIKTO PANEPISTIMIO KYPROU (OPEN UNIVERSITY OF CYPRUS);UNIVERSITY COLLEGE LONDON;MESOKELEAS LTD";"CY;FR;EL;DK;IT;DE;UK";;1;0;0;1;0;0 207003;722642;INTERFUTURE;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2016;H2020;From microbial interactions to new-concept biopesticides and biofertilizers;2016-12-01;2020-11-30;;"The Directive 2009/128/EC sets rules in EU for the sustainable use of pesticides to reduce the risks and impacts of pesticide use on people's health and the environment. Among the listed actions there is the promotion of low pesticide-input management including non-chemical methods. In parallel several chemical active ingredients have been banned because of toxicity concerns. The result is that growers are left with few control tools against pests. On the other hand most of the available alternative control methods have several limitations, especially in term of efficacy. Several new ideas are not reaching the industry and are confined in the academic would. The concept behind this EIT is to explore new approaches to identify new cutting edge solutions for pest control based on new non classical approaches in strict collaboration with industrial partner and to train 10 highly skilled early stage researchers (ESR) through a doctoral programme that integrates 5 academic research with concept-driven product development in 5 EU companies with a strong curriculum in development and innovation within a large interdisciplinary environment. Microorganisms are often used so far as replacement of chemical active ingredients. The innovative aspect of this EID is to base the new pest control solutions on interactions of microorganisms with plants and insects rather than using them as plant protection products. Microorganisms’ unsurpassed inclination towards the association with eukaryotic macro-organisms determines traits and qualities in the host that harbours them. Microbial symbionts’ ability to profoundly transform their living habitat paves the way for unexplored outlooks in the ability to use microbial symbioses as sustainable and renewable tools to improve production and quality in agriculture. Microorganisms are key players in shaping several insect’s semiochemicals, in particular kairomones indicating a food source or oviposition site for some insect species.";2833636,32;2833636,32;H2020-MSCA-ITN-2016;/MSCA-ITN-EID;FONDAZIONE EDMUND MACH;IT;"BIOBEST GROUP NV;UNIVERSITE DE REIMS CHAMPAGNE-ARDENNE;AZOTIC TECHNOLOGIES LIMITED;E-NEMA GESELLSCHAFT FUER BIOTECHNOLOGIE UND BIOLOGISCHEN PFLANZENSCHUTZ mbH;UNIVERSITY OF NEWCASTLE UPON TYNE;UNIVERSITA DEGLI STUDI DEL MOLISE;UNIVERSITAET FUER BODENKULTUR WIEN;BIPA NV;DE CEUSTER MESTSTOFFEN;DESARROLLO AGRICOLA Y MINERO SA;INOQ GmbH";"BE;FR;UK;DE;IT;AT;ES";;1;0;0;1;0;0 198446;647423;SEDAL;SIGNED;H2020-EU.1.1.;ERC-CoG-2014;H2020;Statistical Learning for Earth Observation Data Analysis.;2015-09-01;2020-08-31;;"SEDAL is an interdisciplinary project that aims to develop novel statistical learning methods to analyze Earth Observation (EO) satellite data. In the last decade, machine learning models have helped to monitor land, oceans, and atmosphere through the analysis and estimation of climate and biophysical parameters. Current approaches, however, cannot deal efficiently with the particular characteristics of remote sensing data. In the coming few years, this problem will largely increase: several satellite missions, such as the operational EU Copernicus Sentinels, will be launched, and we will face the urgent need to process and understand huge amounts of complex, heterogeneous, multisource, and structured data to monitor the rapid changes already occurring in our Planet. SEDAL aims to develop the next generation of statistical inference methods for EO data analysis. We will develop advanced regression methods to improve efficiency, prediction accuracy and uncertainties, encode physical knowledge about the problem, and attain self-explanatory models learned from empirical data. Even more importantly, we will learn graphical causal models to explain the potentially complex interactions between key observed variables, and discover hidden essential drivers and confounding factors. This project will thus aboard the fundamental problem of moving from correlation to dependence and then to causation through EO data analysis. The theoretical developments will be guided by the challenging problems of estimating biophysical parameters and learning causal relations at both local and global planetary scales. The long-term vision of SEDAL is tied to open new frontiers and foster research towards algorithms capable of discovering knowledge from EO data, a stepping stone before the more ambitious far-end goal of machine reasoning of anthropogenic climate change.";1716954;1716954;ERC-2014-CoG;/ERC-COG;UNIVERSITAT DE VALENCIA;ES;;;;1;0;0;1;0;0 196795;639750;VIBCONTROL;SIGNED;H2020-EU.1.1.;ERC-StG-2014;H2020;Vibronic control of organic electronic devices;2015-06-01;2020-05-31;;"Organic electronics (OE) is an expanding research field that exploits the electronic functionalities of organic molecules to make them robust and cost-efficient building blocks for future electronic devices. Due to the ‘soft’ character of organic materials, their electronic properties are defined by vibronic coupling (VC) phenomena which are a result of the interaction between electron and nuclear dynamics of the molecule. This research program aims to unlock a new direction of experimental studies investigating and exploiting VC in OE devices by using optical control of nuclear motion. The growing awareness that VC underlies diverse phenomena from physics to biology stimulates a broad interdisciplinary effort to address this issue. However, in the field of OE, the lack of synergy between device and optical studies holds the potential functionality offered by VC effects from being attained. In 2012, I proposed a direct route to control the performance of OE devices by optically switching the vibronic states of the molecules. Though this work came specifically in connection with organic photovoltaics, it provides the starting point for a more fundamental and broad reaching of VC phenomena. The proposed research program will use this opportunity. I will apply state-of-the-art developments in infrared light shaping to create a well-defined coherent superposition of molecular vibrational motions inside devices and study their influence on electron dynamics with device-specific spectroscopic techniques. This approach combines recent advances in ultrafast spectroscopy and OE to extend our fundamental understanding of molecular charge transport. Our methodology will become a tool for elucidating current pathways in organic nanodevices and offer access to non-equilibrium phenomena down to the level of molecular junctions. This research will lead to the development of new design rules for OE materials serving future advances in molecular electronics, computing and sensing.";1497257;1497257;ERC-2014-STG;/ERC-STG;IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE;UK;THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;UK;;1;0;0;1;0;0 196826;642260;TRANSrisk;SIGNED;H2020-EU.3.5.1.;SC5-03a-2014;H2020;Transitions pathways and risk analysis for climate change mitigation and adaption strategies;2015-09-01;2018-12-31;;Both the models concerning the future climate evolution and its impacts, as well as the models assessing the costs and benefits associated with different mitigation pathways face a high degree of uncertainty. There is an urgent need to not only understand the costs and risks associated with climate change but also the risks, uncertainties and co-effects related to different mitigation pathways as well as public acceptance (or lack thereof) of low-carbon (technology) options. The main aims and objectives of TRANSrisk therefore are to create a novel assessment framework for analysing costs and benefits of transition pathways, that will integrate well-established approaches to modelling the costs of resilient, low-carbon pathways with a wider interdisciplinary approach including risk assessments. In addition TRANSrisk aims to design a decision support tool that should help policy makers to better understand uncertainties and risks and enable them to include risk assessments into more robust policy design.;7974242,5;7454017,5;H2020-SC5-2014-two-stage;/RIA;THE UNIVERSITY OF SUSSEX;UK;"NEDERLANDSE ORGANISATIE VOOR TOEGEPAST NATUURWETENSCHAPPELIJK ONDERZOEK TNO;STICHTING JOINT IMPLEMENTATION NETWORK;NATIONAL TECHNICAL UNIVERSITY OF ATHENS - NTUA;STIFTELSEN THE STOCKHOLM ENVIRONMENT INSTITUTE;CAMBRIDGE ECONOMETRICS LIMITED;PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE;UNIVERSITY OF PIRAEUS RESEARCH CENTER;EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH;STICHTING ENERGIEONDERZOEK CENTRUM NEDERLAND;ASOCIACION BC3 BASQUE CENTRE FOR CLIMATE CHANGE - KLIMA ALDAKETA IKERGAI;FUNDACJA NAUKOWA INSTYTUT BADAN STRUKTURALNYCH;UNIVERSITAET GRAZ";"NL;EL;SE;UK;CL;CH;ES;PL;AT";;1;0;0;1;0;0 194554;649008;QLev4G;SIGNED;H2020-EU.1.1.;ERC-CoG-2014;H2020;Quantum control of levitated massive mechanical systems: a new approach for gravitational quantum physics;2015-06-01;2020-05-31;;"Quantum physics and general relativity are probably the most successful and well-tested theories of modern science. At the same time, their fundamental concepts are so dramatically different that there is disagreement on the most obvious questions such as “how does a mass in a quantum superposition state gravitate?“. Achieving progress on such foundational questions requires experiments at the interface between quantum physics and gravity, of which to date only a few of exist. The main objective of the proposed research is to establish quantum control of levitated massive objects as a new paradigm system for such experiments and to enter a hitherto inaccessible parameter regime of large mass and long quantum coherence. The proposal builds on the enormous recent success in quantum control of the motion of solid-state mechanical resonators, which has emerged over the last decade as a new branch of interdisciplinary research in quantum and solid-state physics. Applied to optically or magnetically levitated systems this methodology promises (i) exceptional sensitivity to weak gravitational forces, hence enabling measurements of gravity between sub-millimeter objects; (ii) unprecedented levels of decoupling from the environment, thereby opening up a new route for long-lived quantum coherence of genuinely massive systems. Quantum control is achieved by coupling the motion either of optically trapped particles to an optical cavity field or of magnetically trapped particles to superconducting circuits. We will explore both methods for systematically expanding the available parameter space of macroscopic quantum systems and for first proof-of-concept experiments aimed towards addressing fundamental questions of gravitational quantum physics. If successful, this research program will become a door-opener to the quantum regime of genuinely massive objects, where gravity of the quantum system itself may start to play a role for the correct description of a quantum experiment.";2155285;2155285;ERC-2014-CoG;/ERC-COG;UNIVERSITAT WIEN;AT;;;;1;0;0;1;0;0 194520;648032;DBA;SIGNED;H2020-EU.1.1.;ERC-CoG-2014;H2020;Distributed Biological Algorithms;2015-05-01;2020-04-30;;This project proposes a new application for computational reasoning. More specifically, the purpose of this interdisciplinary project is to demonstrate the usefulness of an algorithmic perspective in studies of complex biological systems. We focus on the domain of collective behavior, and demonstrate the benefits of using techniques from the field of theoretical distributed computing in order to establish algorithmic insights regarding the behavior of biological ensembles. The project includes three related tasks, for which we have already obtained promising preliminary results. Each task contains a purely theoretical algorithmic component as well as one which integrates theoretical algorithmic studies with experiments. Most experiments are strategically designed by the PI based on computational insights, and are physically conducted by experimental biologists that have been carefully chosen by the PI. In turn, experimental outcomes will be theoretically analyzed via an algorithmic perspective. By this integration, we aim at deciphering how a biological individual (such as an ant) “thinks”, without having direct access to the neurological process within its brain, and how such limited individuals assemble into ensembles that appear to be far greater than the sum of their parts. The ultimate vision behind this project is to enable the formation of a new scientific field, called algorithmic biology, that bases biological studies on theoretical algorithmic insights.;1894947;1894947;ERC-2014-CoG;/ERC-COG;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FR;WEIZMANN INSTITUTE OF SCIENCE;IL;;1;0;0;1;0;0 194366;645701;GoMyTri;SIGNED;H2020-EU.1.3.3.;MSCA-RISE-2014;H2020;Golden Mycological Triangle – joining forces to exploit mycological biodiversity for novel anti-infectives and other beneficial metabolites;2015-01-01;2018-12-31;;"The proposed project aims at the intensification of cooperations between research infrastructure organisations in German, the Netherlands and Thailand that are recognised internationally as strongholds in mycological, biotechnological and microbiological research. The cooperation is intended to explore the mycological and microbiological biodiversity of Europe and Southeast Asia, in particular with regard to the search for the badly needed new antibiotics and other biologically active substances. The working plan includes activities such as the systematic exploration of fungal biodiversity by using modern molecular phylogenetic and chemotaxonomic techniques, as well as genome sequencing, in conjunction with classical microbiology. The focus of the research will be set on endophytes (in particular, Xylariaceae and Botryosphaeriaceae), invertebrate-associated ascomycetes (Cordycipitaceae), and marine fungi and fungal-like organisms, respectively. In addition, some basidiomycete cultures will also be studied. Between the participating partners already exist very good personal contacts and smaller research collaborations, which will be intensified in the context of the proposed project. Several staff exchanges and workshops are planned, which should allow the partners to further increase and optimise their interactions and to attain interdisciplinary skills. In the medium term the project is aimed at attaining an internationally visible strategic cooperation, including other departments of the institutions involved.";333000;333000;H2020-MSCA-RISE-2014;/MSCA-RISE;HELMHOLTZ-ZENTRUM FUR INFEKTIONSFORSCHUNG GMBH;DE;KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW;NL;;1;0;0;1;0;0 194561;649180;NET4SOCIETY4;SIGNED;H2020-EU.3.6.;REFLECTIVE-10-2014;H2020;Transnational network of National Contact Points (NCPs) of Societal Challenge 6 'Europe in a changing world - inclusive, innovative and reflective Societies' (SC6);2015-02-01;2019-01-31;;"NET4SOCIETY4 will be the transnational network of National Contact Points (NCPs) for Societal Challenge 6 (SC6) “Inclusive, innovative, and reflective societies” in Horizon 2020. NCPs are set up to guide researchers in their quest for securing EU funding. NET4SOCIETY4 will further develop the current NET4SOCIETY network of SC6 NCPs (former NCPs for Socio-economic Sciences and Humanities), which was first established in 2008 and includes currently around 80 SC6 NCPs from Europe and beyond. NET4SOCIETY4 will ensure that all SC6 NCPs have the relevant knowledge and skills for their work and can offer professional, high-quality and tailor-made services to applicants. All nominated SC6 NCPs (also non-beneficiaries) will have access to information and capacity building tools such as workshops, NCP Info days, trainings, webinars, factsheets or newsletters. NET4SOCIETY4 foresees targeted activities to support applicants in SC6. The project will facilitate interdisciplinary and international consortium building through the organisation of brokerage events, through a dedicated partner search service and through a research directory of SC6 key players. In addition, NET4SOCIETY4 will organise expert meetings e.g. on “impact” of SC6 research and disseminate the meetings’ results to NCPs and applicants. To support the successful implementation of “embedding” Socio-economic Sciences and Humanities (SSH) in all parts of Horizon 2020, NET4SOCIETY4 will carry out surveys on the integration of SSH in Horizon 2020. The project will publish success stories and factsheets on “embedding”, as well as a document listing funding opportunities for SSH in all of Horizon 2020. NET4SOCIETY4 will organise two large conferences in the thematic area of SC6 to provide visibility to the funding programme and the possibility to discuss future research needs. Various promotion activities enhancing the visibility of NET4SOCIETY4 services and the SC6 in Horizon 2020 will underline these efforts.";3086989,37;2999989;H2020-REFLECTIVE-SOCIETY-2014;/CSA;DEUTSCHES ZENTRUM FUER LUFT - UND RAUMFAHRT EV;DE;"RANNSOKNAMIDSTOD ISLANDS;FUNDACION ESPANOLA PARA LA CIENCIA Y LA TECNOLOGIA;BELARUSIAN STATE UNIVERSITY;IDRYMA PROOTHISIS EREVNAS;AGENZIA PER LA PROMOZIONE DELLA RICERCA EUROPEA;CENTRUM VEDECKO TECHNICKYCH INFORMACII SLOVENSKEJ REPUBLIKY;INSTYTUT PODSTAWOWYCH PROBLEMOW TECHNIKI POLSKIEJ AKADEMII NAUK;AGENCIJA ZA MOBILNOST I PROGRAME EUROPSKE UNIJE;RESEAU FRANCAIS DES INSTITUTS D'ETUDES AVANCEES;AGENCIA ANDALUZA DEL CONOCIMIENTO;VEREIN EURESEARCH;ETHNIKO IDRYMA EREVNON;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;OESTERREICHISCHE FORSCHUNGSFOERDERUNGSGESELLSCHAFT MBH;FUNDACAO PARA A CIENCIA E A TECNOLOGIA";"IS;ES;BY;CY;IT;SK;PL;HR;FR;CH;EL;AT;PT";;1;0;0;1;0;0 196772;637878;lincSAFARI;SIGNED;H2020-EU.1.1.;ERC-StG-2014;H2020;Sequence and Function Relationships in Long Intervening Noncoding RNAs;2015-06-01;2020-05-31;;"It is now clear that many intergenic regions in eukaryotic genomes give rise to a range of processed and regulated transcripts that do not appear to code for functional proteins. A subset of these are long (>200 nt), capped and polyadenylated RNAs transcribed by RNA polymerase II and collectively called long intervening noncoding RNAs or lincRNAs. The recent estimates are that the human genome encodes >10,000 distinct lincRNAs, many of which show tissue-specific expression and are frequently dysregulated in human disease, including neurodegeneration. Given the growing number of lincRNAs implicated in human disease or required for proper development, fundamental questions that need to be addressed are: Which lincRNAs are functional? How is functional information encoded in the lincRNA sequence? Is this information interpreted in the context of the mature or the nascent RNA? What are the identities and functional roles of specific sequence domains within lincRNA genes? Our main hypothesis is that many lincRNA loci play key roles in gene regulation during cell differentiation, both via functionally important transcription events and post-transcriptionally, through the combined action of multiple short sequence domains. We will test this hypothesis using three complementary approaches – comparative genomics, detailed perturbations in mammalian cells followed by quantitative molecular phenotyping, and high-throughput screens for sequences able to carry out specific functions. We propose an interdisciplinary approach combining computational, molecular and stem cell biology. Our methodology will be scalable, allowing us to tackle completely uncharacterized long RNAs and eventually zoom in and study their individual bases. Upon successful accomplishment of the program, we will delineate modes of action of numerous lincRNAs, report sequence patches that are functionally important and understand how specific bases and structures act in concert to drive lincRNA function.";1500000;1500000;ERC-2014-STG;/ERC-STG;WEIZMANN INSTITUTE OF SCIENCE;IL;;;;1;0;0;1;0;0 216475;777084;DynaMORE;SIGNED;H2020-EU.3.1.5.;SC1-PM-17-2017;H2020;Dynamic MOdelling of REsilience;2018-04-01;2023-03-31;;"The project DynaMORE (Dynamic MOdelling of REsilience) exploits advanced mathematical modelling for the promotion of mental health and well-being. DynaMORE will generate the first personalised in-silico model of mental health in the face of adversity, that is, stress resilience. The model will be based on and validated against unique multi-scale longitudinal real-world empirical data sets. The development and testing of the model will substantially deepen our scientific understanding of the mechanisms of resilience. These insights will allow us to create mechanistically targeted interventions for the primary prevention of stress-related disorders. On this basis, DynaMORE will develop an entirely new mHealth product that will include model-based prognostic tools for monitoring of at-risk subjects and for automatised decision-making about timed, personalised interventions. The DynaMORE model will be openly available, whereas the interventions and surrounding application solutions (data analysis tools, information and communication technology (ICT)) will have a strong potential for commercial exploitation, which will be actively prepared within DynaMORE. These objectives will be achieved through the interdisciplinary collaboration of world-leading experts in the fields of (1) computer-modelling and simulation and multi-scale data integration (project area MODELLING), (2) bio-psycho-social research on mental health and resilience (area HUMAN LIVES), and (3) mHealth technology, including ambulatory monitoring and intervention, and ICT (area TECHNOLOGY). These will be supported, and results will be exploited, by an experienced management and impact maximisation team (area IMPACT). The overall aim of DynaMORE is to improve human lives by preventing stress-related mental health problems. DynaMORE’s health-focussed strategy will promote individual well-being and reduce healthcare demands and indirect economic costs, by contributing to a healthy and productive workforce.";6069015;6069015;H2020-SC1-2017-CNECT-2;/RIA;UNIVERSITAETSMEDIZIN DER JOHANNES GUTENBERG-UNIVERSITAET MAINZ;DE;"STICHTING IMEC NEDERLAND;UNIWERSYTET WARSZAWSKI;STICHTING KATHOLIEKE UNIVERSITEIT;INTERUNIVERSITAIR MICRO-ELECTRONICA CENTRUM;ALBERT-LUDWIGS-UNIVERSITAET FREIBURG;INTERNATIONAL RESILIENCE ALLIANCE EV;CHARITE - UNIVERSITAETSMEDIZIN BERLIN;TEL AVIV UNIVERSITY;UNIVERSITAT ZURICH;UNIVERSITAETSKLINIKUM FREIBURG;KATHOLIEKE UNIVERSITEIT LEUVEN;Concentris Research Management GmbH";"NL;PL;BE;DE;IL;CH";;1;0;0;1;0;0 216413;774210;CO-CREATE;SIGNED;H2020-EU.3.2.2.2.;SFS-39-2017;H2020;Confronting Obesity: Co-creating policy with youth;2018-05-01;2023-04-30;;"CO-CREATE aims to reduce childhood obesity and its co-morbidities by working with adolescents, to create, inform and disseminate obesity-preventive evidence-based policies. The project applies a systems approach to provide a better understanding of how factors associated with obesity interact at various levels. The project focus on adolescence as the specific target group, a crucial age with increasing autonomy and the next generation of adults, parents and policymakers, and thus important agents for change. CO-CREATE involve and empower adolescents and youth organizations to foster a participatory process of identifying and formulating relevant policies, deliberating such options with other private and public actors, promoting relevant policy agenda and tools and strategies for implementation. CO-CREATE strengthen interdisciplinary research and have an inclusive multi-actor approach with involvement of academics, policy makers, civil society, relevant industry and market actors to ensure long-lasting implementation of the results. The project reflects and builds on a number of existing initiatives and platforms, including the extensive research activity from consortium members. The project has a strong gender profile and consider the relevance of geographic, socio-economic, behaviour and cultural factors. CO-CREATE engages international partners from different policy-contexts in Europe, Australia, South Africa and the US. Applying large-scale datasets, policy monitoring tools, novel analytical approaches and youth involvement will provide new efficient strategies, tools and programmes for promoting sustainable and healthy dietary behaviours and lifestyles. The generated knowledge and innovative tools for assessing actual policy implementation, strategies for empowering adolescents; and strategies for identifying, implementing and monitoring relevant policy programmes are applicable to stakeholders involved in the European efforts to tackle childhood obesity.";9757943,75;9678653,75;H2020-SFS-2017-2;/RIA;FOLKEHELSEINSTITUTTET;NO;"CENTRO DE ESTUDOS E INVESTIGACAO EM DINAMICAS SOCIAIS E SAUDAE ASSOCIACAO SEM FINS LUCRATIVOS;UNIVERSITY OF CAPE TOWN;WORLD OBESITY FEDERATION;EAT STOCKHOLM FOOD FORUM AS;LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE;DEAKIN UNIVERSITY;UNIVERSITETET I OSLO;THE UNIVERSITY OF TEXAS SYSTEM;SWPS UNIWERSYTET HUMANISTYCZNOSPOLECZNY;WORLD CANCER RESEARCH FUND INTERNATIONAL I A;UNIVERSITETET I BERGEN;PRESS;UNIVERSITEIT VAN AMSTERDAM";"PT;ZA;UK;NO;AU;US;PL;BE;NL";;1;0;0;1;0;0 198797;681120;SmokeFreeBrain;SIGNED;H2020-EU.3.1.3.;HCO-06-2015;H2020;Multidisciplinary tools for improving the efficacy of public prevention measures against smoking;2015-11-01;2018-10-31;;"Smoking is the largest avoidable cause of preventable morbidity worldwide. It causes most of the cases of lung cancer and chronic obstructive pulmonary disease (COPD) and contributes to the development of other lung diseases. The control of smoking is considered as a highly important intervention for the prevention of lung diseases. Tobacco consumption is highly influenced by socioeconomic factors. SmokeFreeBrain aims to address the effectiveness of a multi-level variety of interventions aiming at smoking cessation in high risk target groups within High Middle Income Countries (HMIC) such as unemployed young adults, COPD and asthma patients, as well as within the general population in Low Middle Income Countries (LMIC). The project addresses existing approaches aiming to prevent lung diseases caused by tobacco while at the same time it develops new treatments and analyzes their contextual adaptability to the local and global health care system. SmokeFreeBrain follows an interdisciplinary approach exploiting consortium’s expertise in various relevant fields in order to generate new knowledge. State of the art techniques in toxicology, pulmonary medicine, neuroscience and behavior will be utilized to evaluate the effectiveness of: (i) Public Service Announcement (PSA) against smoking, (ii) the use of electronic cigarettes with and without nicotine as a harm reduction approach and/or cessation aid, (iii) a specifically developed neurofeedback intervention protocol against smoking addiction, (iv) a specifically developed intervention protocol based on behavioral therapy, social media/mobile apps and short text messages (sms) and (v) pharmacologic interventions. The main objective of the project is to evaluate the interventions in terms of health economics, by studying their cost-effectiveness, and proposing a scalable plan and a clear pathway to embedding the proposed interventions into policy and practice both in LMIC as well as in HMIC.";3187865,2;2981001;H2020-HCO-2015;/RIA;ARISTOTELIO PANEPISTIMIO THESSALONIKIS;EL;"NATIONAL ASSOCIATION OF GENERAL PRACTITIONERS IN BULGARIA;INSTITUT ZA PLUCNE BOLESTI VOJVODINE;Department of Health;UNIVERSITY OF PIRAEUS RESEARCH CENTER;ST GEORGE'S HOSPITAL MEDICAL SCHOOL;KENTRO NEVROANADRASIS VORIOU ELLADOS EE;SERVICIO ANDALUZ DE SALUD;AAI SCIENTIFIC CULTURAL SERVICES LIMITED;SALUMEDIA TECNOLOGIAS SL;UNIVERSITY OF SURREY;HELLENIC OPEN UNIVERSITY;UNIVERSITA DEGLI STUDI DI ROMA LA SAPIENZA;TAIPEI MEDICAL UNIVERSITY FOUNDATION*TMU;UNIVERSIDAD DE SEVILLA";"BG;RS;UK;EL;ES;CY;IT;TW";;1;0;0;1;0;0 213758;763911;eForFuel;SIGNED;"H2020-EU.3.3.5.;H2020-EU.3.3.2.;H2020-EU.3.3.3.";LCE-06-2017;H2020;Fuels from electricity: de novo metabolic conversion of electrochemically produced formate into hydrocarbons;2018-03-01;2022-02-28;;For biorefined fuels to fully replace fossil carbons, we must identify feedstock sources which are essentially unlimited in capacity and scalability and are independent of agriculture and forestry land use. Here, we propose to use electricity – preferably produced from renewable sources and at off pick hours – as the sole energy source for microbial growth and the conversion of CO2 into fuels. We aim to tackle the shortcoming of previous technologies by using completely soluble formate as a mediator between electrical current and living cells. Within an integrated electrobioreactor, CO2 will be reduced to formate at a very high rate, and the formate will be consumed by an engineered E. coli to produce propane and isobutene, gaseous hydrocarbons that are easy to separate from the liquid broth. Both propane and isobutene can be further converted into a range of products, including excellent fuel substitutes (e.g., isooctane), using conventional chemical engineering methodologies. Our approach comprises a truly interdisciplinary effort. Material scientists will design novel electrode compositions and structures, which will be used by electrochemists to optimize electrochemical formate production at high efficiency and current density. Metabolic engineers will adapt E. coli for growth on formate via two synthetic formate assimilation pathways, specifically designed to fit the metabolism of this model bacterium. Synthetic pathways for propane and isobutene biosynthesis will be implemented in the formatotrophic strains. Process engineers will construct a unique electrobioreactor to support simultaneous formate production and consumption. Experts in environmental assessment will analyze the benefits of the suggested technology, and the project vision and results will be disseminated to the scientific community and general public. The technology put forward in this proposal could have a transformative effect on the way we produce our chemicals and fuels.;4117207,5;4117207,5;H2020-LCE-2017-RES-RIA-TwoStage;/RIA;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;DE;"UNIVERSIDAD DE ALICANTE;BIOFACTION KG;IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE;WEIZMANN INSTITUTE OF SCIENCE LTD;COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES;SINTEF AS;C3 BIO-TECHNOLOGIES LIMITED;IFEU - INSTITUT FUR ENERGIE UND UMWELTFORSCHUNG HEIDELBERG GMBH;IN SRL;UNIVERSITAET STUTTGART;ARCELORMITTAL BELGIUM NV;ALTAR;GLOBAL BIOENERGIES";"ES;AT;UK;IL;FR;NO;DE;IT;BE";;1;0;0;1;0;0 213171;780819;INSENSION;SIGNED;H2020-EU.2.1.1.;ICT-23-2017;H2020;Personalized intelligent platform enabling interaction with digital services to individuals with profound and multiple learning disabilities;2018-01-01;2020-12-31;;The INSENSION project will create an ICT platform that enables persons with profound and multiple learning disabilities (PMLD) to use digital applications and services that can enhance the quality of their lives, increase their ability to self-determination and enrich their lives. The target end users of the proposed solution are capable of using only nonconventional, nonsymbolic means of interaction with their environment. Therefore, the platform aims to provide technological means for seamless, and adaptable recognition of a range of highly individual nonsymbolic behavioral signals of people with PMLD to detect behavioral patterns happening in the context of specific situations. These patterns are translated into the affective ‘intents’ of the end user (their approval or disapproval to the given situation) and allow to communicate them to assistive services. This way an individual with PMLD gains a possibility to seamlessly influence their living environment, through new means of communication with other people, changing conditions of their environment or use new types of assistive digital applications. The project employs recent advances in a range of ICT disciplines equipping the proposed assistive ICT platform with natural behavior recognition mechanisms based on gesture, facial expression and vocalization recognition technologies. This is complemented by novel techniques of artificial intelligence and state-of-the-art Internet of Things models. The research and development of the project is conducted within the inclusive design paradigm, with individual with PMLD and their caregivers directly participating in the R\D process throughout the whole duration of the project. This process links a highly interdisciplinary team of experts of ICT specialists and researchers and practitioners of disability studies and care, with due participation of an assistive technology industry representatives.;2255875;2255875;H2020-ICT-2017-1;/RIA;INSTYTUT CHEMII BIOORGANICZNEJ POLSKIEJ AKADEMII NAUK;PL;"INSTITUT JOZEF STEFAN;FUNDACION CTIC CENTRO TECNOLOGICO PARA EL DESARROLLO EN ASTURIAS DE LAS TECNOLOGIAS DE LA INFORMACION;Harpo Sp. z o. o.;PADAGOGISCHE HOCHSCHULE HEIDELBERG;STOWARZYSZENIE NA TAK";"SI;ES;PL;DE";;1;0;0;1;0;0 193964;642929;SUPRABARRIER;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2014-EID;H2020;SUPRAmolecular polyolefins as oxygen BARRIER materials;2015-01-01;2018-12-31;;The production of the next generation of oxygen-barrier polyolefins materials capable of meeting the current and future demands of society in a sustainable manner will require both new technologies and highly trained scientists. Supramolecular chemistry provides a powerful approach to develop new materials with emerging properties, such as low permeability to oxygen, maintaining easy processing. The SUPRABARRIER EID ITN will train a new generation of European scientists with the skills necessary to overcome such future demands and simultaneously develop new strategies for the production of new polymeric systems, which greatly impact important fields such as food and medical packaging. The EID proponents are experts in the areas of supramolecular chemistry and polymer production. Expertise of the partners encompasses the general areas of supramolecular and polymer chemistry, with individual research competencies focusing on a number of specific themes including non-covalent chemistry, supramolecular interactions, polymer blending, polymer processing, polymer production, and Life Cycle Assessment (LCA) analysis and characterisation techniques of complex polymeric and self-assembled materials. The complementarity and diversity realized in synthesis, analysis, development, production and applications is crucial for successful research, innovation and training in this area. The partner from the private sector will extend the fellows’ training beyond that of traditional academic settings, in particular he will have the critical role of bridging fundamental science with application and commercialisation of the results. Our activities will thus possess both breadth and quality that can only be achieved through an interdisciplinary Academy/Industrial European effort.;513435,6;513435,6;H2020-MSCA-ITN-2014;/MSCA-ITN-EID;UNIVERSITA DEGLI STUDI DI PARMA;IT;SABIC PETROCHEMICALS BV;NL;;1;0;0;1;0;0 205525;721733;EIPIN IS;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2016;H2020;European Intellectual Property Institutes Network - Innovation Society;2017-03-01;2021-02-28;;"EIPIN IS is a comprehensive project at the forefront of multidisciplinary research, examining the role of intellectual property (IP) as a complex adaptive system in innovation. The focus will be on the European regulatory framework for fostering innovation with the aim of enhancing Europe’s capacity for innovation-based sustainable economic growth. The longstanding European Intellectual Property Institutes Network (EIPIN), a consortium of leading research and training centres in the area of intellectual property, is the driving force behind the project. The primary research objective of the programme is to provide political leaders and stakeholders reliable conclusions and recommendations in the form of doctoral IP research on how to deal with the adaptive complexities of innovation cycles that secure economic benefits and uphold justice in the innovation society. The training objectives of the programme focus on the development of ESR’s capacity to guide inventors and entrepreneurs in the life-cycle of IP-intensive assets and the process of translating intangible inventions into commercially viable products. The programme provides for an unprecedented environment for ESRs, based on the award of a joint or double doctoral degree. The project results will be disseminated in a way that it has an impact on the norm-setting at the national, European and international level. The involvement of industry associations representing numerous undertakings multiplies the engagement of non-academic actors. Furthermore, the realisation of this ambitious interdisciplinary programme open to ESRs from all domains of sciences will provide a solid foundation for further cross-cutting research in the area of innovation policies, overcoming traditional divisions between faculties and disciplines. This partnership has a high potential for the broadest possible dissemination of its results as well as becoming a role model in Europe.";3865881,6;3865881,6;H2020-MSCA-ITN-2016;/MSCA-ITN-EJD;UNIVERSITEIT MAASTRICHT;NL;"UNIVERSIDAD DE ALICANTE;UNIVERSITE DE STRASBOURG;UNIVERSITAET AUGSBURG;QUEEN MARY UNIVERSITY OF LONDON";"ES;FR;DE;UK";;1;0;0;1;0;0 193989;643084;BASE-LiNE Earth;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2014-ETN;H2020;Brachiopods As SEnsitive tracers of gLobal marINe Environment: Insights from alkaline, alkaline Earth metal, and metalloid trace element ratios and isotope systems;2015-01-01;2018-12-31;;'Data on seawater composition since the start of the Phanerozoic eon ~540 million years ago provide essential information for understanding long-term chemical processes of socio-economic dimension like the evolution of life, land-ocean interaction, atmospheric chemistry, ecosystem adaptation to climate change, oceanic trace metal cycling, and for applied geological processes like the formation of submarine energy resources. Although partly known this knowledge is still limited pending new methodical prospects and innovative analytical techniques. Following this approach, the proposed ETN 'BASE-LiNE Earth' will train early stage researchers (ESRs) who will extend the knowledge of the complex and long-term Phanerozoic seawater history by the determination of original proxy information preserved in reliable ancient geological archives using cutting edge technologies and experimental approaches. In order to amplify this process the ESRs will be exposed to academic and non-academic high-tech institutions linking biogeochemical research and training in biology, ecology, geochemistry as well as chemical analytics to engineering and cutting edge analytical instrumentation. Multi- and interdisciplinary environments will expose our ESRs to highly demanded transferable skills increasing their employability when it comes to job application. 'BASE-LiNE Earth' will offer societally important deliverables like time series of past trace element and isotope cycling and models about ocean material fluxes in and out of the Phanerozoic Ocean. This will be shared in publications, reports and exhibitions. Interactive lecturing material will be offered for education in general and specifically for high school teachers. Through collaboration with high-tech companies the ETN will contribute to establish both, new approaches for the exploration of hydrocarbon reservoirs and innovative and sophisticated analytical instrumentation for trace element and isotope measurements.';3749331,24;3749331,24;H2020-MSCA-ITN-2014;/MSCA-ITN-ETN;HELMHOLTZ ZENTRUM FUR OZEANFORSCHUNG KIEL;DE;"INSTYTUT PALEOBIOLOGII IM.ROMANA KOZLOWSKIEGO POLSKIEJ AKADEMII NAUK;JOANNEUM RESEARCH FORSCHUNGSGESELLSCHAFT MBH;LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN;TECHNISCHE UNIVERSITAET GRAZ;KOBENHAVNS UNIVERSITET;JR-AQUACONSOL GMBH;INSTITUT DE PHYSIQUE DU GLOBE DE PARIS;JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN;THERMO FISHER SCIENTIFIC (BREMEN) GMBH;CESKA GEOLOGICKA SLUZBA;UNIVERSITA DEGLI STUDI DI MILANO;THE HEBREW UNIVERSITY OF JERUSALEM;USTAV VIED O ZEMI SLOVENSKEJ AKADEMIE VIED;CESKA ZEMEDELSKA UNIVERZITA V PRAZE";"PL;AT;DE;DK;FR;CZ;IT;IL;SK";;1;0;0;1;0;0 193623;639084;LEGALARCHITECTURES;SIGNED;H2020-EU.1.1.;ERC-StG-2014;H2020;Legal Architectures: The Influence of New Environmental Governance Rules on Environmental Compliance;2015-07-01;2020-06-30;;Non-compliance with the EU’s environmental rules is one of the key weaknesses of the EU’s environmental policy. This research investigates the influence that environmental governance laws have on compliance decisions, and how we might best design our laws to maximise compliance. One of the most important trends in European environmental regulatory techniques over the past decade has been the shift from hierarchical, state-led government via command-and-control techniques, to decentralised, society-led governance by local private actors (see, e.g., Jordan et al (2013)). The EU has strongly supported efforts to empower compliance and enforcement by non-State actors, as embodied in the UNECE Aarhus Convention and implementing laws. Yet little is known about how this major change in environmental governance laws has actually influenced compliance levels in practice, and why. Can the design of environmental governance rules influence us not only to comply with the letter of the law, but also to go further? This research seeks to fill that gap by means of an interdisciplinary, bottom-up study of the relationships between the legal architecture of environmental governance and compliance decisions, in a selected field of EU environmental policy (biodiversity), and in three selected States. It is novel in terms of theory, because it tests new hypotheses about the effects environmental governance rules have on compliance. It is novel in terms of methodology, because in testing these hypotheses, it uses techniques that have not up to now been applied to measure the effect of law. It is challenging, because it sits at the intersection between the law and economics, socio-legal and governance/regulatory literatures, and brings together multiple methods from these fields to test its hypotheses. It has potentially high impact, because non-compliance is one of the most serious problems the EU’s environmental policy faces, and is closely linked to environmental outcomes.;1494650;1494650;ERC-2014-STG;/ERC-STG;UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN;IE;;;;1;0;0;1;0;0 193667;639720;NAPOLI;SIGNED;H2020-EU.1.1.;ERC-StG-2014;H2020;Nanoporous Asymmetric Poly(Ionic Liquid) Membrane;2015-03-01;2021-01-31;;"Nanoporous polymer membranes (NPMs) play a crucial, irreplaceable role in fundamental research and industrial usage, including separation, filtration, water treatment and sustainable environment. The vast majority of advances concentrate on neutral or weakly charged polymers, such as the ongoing interest on self-assembled block copolymer NPMs. There is an urgent need to process polyelectrolytes into NPMs that critically combine a high charge density with nanoporous morphology. Additionally, engineering structural asymmetry/gradient simultaneously in the membrane is equally beneficial, as it would improve membrane performance by building up compartmentalized functionalities. For example, a gradient in pore size forms high pressure resistance coupled with improved selectivity. Nevertheless, developing such highly charged, nanoporous and gradient membranes has remained a challenge, owing to the water solubility and ionic nature of conventional polyelectrolytes, poorly processable into nanoporous state via common routes. Recently, my group first reported an easy-to-perform production of nanoporous polyelectrolyte membranes. Building on this important but rather preliminary advance, I propose to develop the next generation of NPMs, nanoporous asymmetric poly(ionic liquid) membranes (NAPOLIs). The aim is to produce NAPOLIs bearing diverse gradients, understand the unique transport behavior, improve the membrane stability/sustainability/applicability, and finally apply them in the active fields of energy and environment. Both the currently established route and the newly proposed ones will be employed for the membrane fabrication. This proposal is inherently interdisciplinary, as it must combine polymer chemistry/engineering, physical chemistry, membrane/materials science, and nanoscience for its success. This research will fundamentally advance nanoporous membrane design for a wide scope of applications and reveal unique physical processes in an asymmetric context.";1500000;1500000;ERC-2014-STG;/ERC-STG;STOCKHOLMS UNIVERSITET;SE;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;DE;;1;0;0;1;0;0 193394;636307;FLEXOP;SIGNED;H2020-EU.3.4.;MG-1.1-2014;H2020;Flutter Free FLight Envelope eXpansion for ecOnomical Performance improvement;2015-06-01;2019-11-30;;"The FLEXOP project is about developing multidisciplinary aircraft design capabilities for Europe that will increase competitiveness with emerging markets -particularly in terms of aircraft development costs. A closer coupling of wing aeroelasticity and flight control systems in the design process opens new opportunities to explore previously unviable designs. Common methods and tools across the disciplines also provide a way to rapidly adapt existing designs into derivative aircraft, at a reduced technological risk (e.g. using control to solve a flutter problem discovered during development). The goal will be achieved by: (a) improving efficiency of currently existing wing, by increased span at no excess structural weight, while establishing modifications by aeroelastic tailoring to carry the redesigned derivative wing; (b) developing methods and tools for very accurate flutter modeling and flutter control synthesis, to enable improved flutter management during development, certification, and operation, enabling to fly with the stretched wing at same airspeed as the baseline aircraft; (c) validating the accuracy of developed tools and methods on an affordable experimental platform, followed by a scale-up study, demonstrating the interdisciplinary development cycle. Manufacturers will gain cost efficient methods, tools and demonstrators for enhancing aircraft performance by integrated development of flutter control and aeroelastic tailoring. These inter-disciplinary capabilities will improve the design cycle and the Verification& Validation process of both derivative and new aircraft. Better control of development and certification costs can be achieved if these capabilities are used to address problems early in the design process. Flight test data will be posted on the project website to provide a benchmark for the EU aerospace community. The project’s results will serve as a preliminary outlining of certification standards for future EU flexible transport aircraft.";6692164,38;6692163,75;H2020-MG-2014_TwoStages;/RIA;MAGYAR TUDOMANYOS AKADEMIA SZAMITASTECHNIKAI ES AUTOMATIZALASI KUTATOINTEZET;HU;"INASCO HELLAS ETAIREIA EFARMOSMENON AERODIASTIMIKON EPISTIMON EE;RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN;TECHNISCHE UNIVERSITAET MUENCHEN;AIRBUS DEFENCE AND SPACE GMBH;DEUTSCHES ZENTRUM FUER LUFT - UND RAUMFAHRT EV;UNIVERSITY OF BRISTOL;AIRBUS GROUP LIMITED;FISCHER ADVANCED COMPOSITE COMPONENTS AG*FACC AG;TECHNISCHE UNIVERSITEIT DELFT";"EL;DE;UK;AT;NL";;1;0;0;1;0;0 193310;634880;EDC-MixRisk;SIGNED;H2020-EU.3.1.1.;PHC-01-2014;H2020;Integrating Epidemiology and Experimental Biology to Improve Risk Assessment of Exposure to Mixtures of Endocrine Disruptive Compounds;2015-05-01;2019-04-30;;"A large body of evidence supports associations between exposure to anthropogenic chemicals and endocrine disruptive effects, leading to disorders in humans and wildlife. Based on the scientific documentation it is beyond doubt that endocrine disrupting chemicals (EDCs) are of concern and need to be handled according to the risks they pose, as single chemicals or as mixtures. To develop chemical risk assessment to respond to these concerns, there is an urgent need to improve our understanding of the mechanisms and health effects of EDCs, in particular in mixtures. This will require selection, refinement and development of tools for assessment of EDC mixtures to bring current risk assessment procedures to a level where they can support risk management. This project is designed to promote the use of safe chemicals for the next generation. EDC-MixRisk aims to meet the societal need for improved decision-making regarding human exposure risks to mixtures of EDCs. EDC-MixRisk will determine risks for multiple adverse health outcomes based on molecular mechanisms involved after early life exposure to EDC mixtures. The task is approached through interdisciplinary cooperation between experts in epidemiology, experimental toxicology and molecular biology, and risk assessment. The value of this combined research effort is: i) Identification of EDC mixtures that are associated with multiple adverse health outcomes in three health domains (growth and metabolism, neurodevelopment and sexual development) in epidemiology; ii) Identification of molecular mechanisms and pathways underlying the associations between exposure and adverse health outcomes by the use and development of state-of-the-art experimental models and iii) Development of a transparent and systematic framework in risk assessment for integrating epidemiological and experimental research to facilitate the assessment of risk and societal impact, thus promoting better risk management for EDCs and their mixtures.";6223330;6223330;H2020-PHC-2014-two-stage;/RIA;KAROLINSKA INSTITUTET;SE;"ISTITUTO EUROPEO DI ONCOLOGIA SRL;LUNDS UNIVERSITET;ETHNIKO KAI KAPODISTRIAKO PANEPISTIMIO ATHINON;UPPSALA UNIVERSITET;UNIVERSITAET LEIPZIG;TERVEYDEN JA HYVINVOINNIN LAITOS;OREBRO UNIVERSITY;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI;GOETEBORGS UNIVERSITET;KARLSTADS UNIVERSITET;STOCKHOLMS UNIVERSITET";"IT;SE;EL;DE;FI;FR;US";;1;0;0;1;0;0 221436;814299;CHARISMA;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2018;H2020;ENTREPRENEURING CHEMICAL IRREVERSIBILITY TO PROTOTYPE RESPONSIVE SMART LABELS;2019-04-01;2023-03-31;;In a world in which sensors are multiplying to give information to people, a need to represent these messages in an appealing and unequivocal way appears as one of the new challenges in information and communication technologies. It is with this idea, that the CHARISMA Industrial Doctoral Training elevates the concept of applied irreversibility to displays, empowering packaging industries with the tools and innovative advanced materials to engineer smart labels. CHARISMA develops printable smart labels that, capitalizing on a sensor responsive to an external stimulus (e.g., temperature), will allow the irreversible colour change of a chromogenic displaying unit. All this is connected through a circuitry that, through a powered capacitor or an OPV device, can allow the stimulus response and trigger a chromogenic (e.g., electrochromic) switching event. Once the signal is transmitted to the chromogenic display, the display will turn colour (e.g., into black), and this state cannot be converted back. The CHARISMA smart labels are thin and flexible taking virtually no space, and thus printable on any surface. The project brings together 9 ESRs in a strong interdisciplinary consortium of five beneficiaries, industry and research balanced, with state-of-the-art backgrounds in synthetic chemistry, printing, electronics system integration, and complete chromogenic solutions. This is complemented with the commitment of four non-academic partner organizations. The CHARISMA’s ESRs will be exposed to industrial training program on smart labels, in which theoretical and practical research schemes in device engineering and innovation are integrated with topical themes and methods imported from chemistry, physics and business.;2452146,48;2452146,48;H2020-MSCA-ITN-2018;/MSCA-ITN-EID;CARDIFF UNIVERSITY;UK;"LCR HALLCREST LIMITED;UNIVERSIDADE NOVA DE LISBOA;TAMPEREEN KORKEAKOULUSAATIO SR;YNVISIBLE GMBH";"UK;PT;FI;DE";;1;0;0;1;0;0 221445;819213;SECURITY FLOWS;SIGNED;H2020-EU.1.1.;ERC-2018-COG;H2020;Enacting border security in the digital age: political worlds of data forms, flows and frictions.;2019-06-01;2024-05-31;;Datafication, the process transforming our everyday lives into quantifiable digital data, is also transforming borders today. Data collection, exchange and interoperability have become key for EU border security. How does data enact border security in the digital age? What are the political and ethical implications of these processes of datafication? This project proposes to develop a novel interdisciplinary framework to understand how data is generated, exchanged and contested in border encounters, and to investigate the complex epistemic, practical, political and ethical implications of these transformations. Starting from a socio-material reconceptualisation of datafication as the production of data forms, flows and frictions, the project advances an innovative theorisation of the (i)epistemic effects of datafication as producing both knowledge and ignorance. It will shed light on how data forms make things intelligible or unintelligible, and how digital data flows and frictions redistribute knowledge and ignorance among border security actors, NGOs and irregular migrants. To trace the (ii)practical implications of datafication, the project will devise a multi-modal methodology for 'following the data' along the Eastern, Central and Mediterranean routes as well as the routes leading to these from Morocco, Niger and Turkey, and finally along return routes. (iii)Politically, the project investigates how data reconfigures the worlds of actors involved in the governance of border security by enacting new power relations between these actors and reshaping decision-making. Finally, the project also advances a socio-material approach to (iv)ethics to account for how data protection and the rights of both citizens and non-citizens are transformed by datafication. Through its ambitious theoretical and methodological innovations, which will shape an emergent field of research, the project will have long-lasting impact for border and security studies.;1897826;1897826;ERC-2018-COG;/ERC-COG;KING'S COLLEGE LONDON;UK;;;;1;0;0;1;0;0 212130;766058;VIRO-FLOW;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2017;H2020;Enabling Technologies and Drug Discovery: Continuous Flow Processes to Discover Novel Antiviral Inhibitors;2017-11-01;2021-10-31;;"VIRO-FLOW project aims to integrate the advantages of continuous flow chemistry with in vitro microfluidic bioassay technologies for the fast and efficient discovery of novel and innovative inhibitors of the Hepatitis B Virus (HBV). This programme aims to contribute to the development of innovative methodologies that allow more efficient production of new compounds with anti-viral activity, specifically against HBV, for future transfer of technology and knowledge between different sectors with relevant economic impact. The global objective of this ITN-EID programme is to provide an innovative and high-level training in drug discovery and enabling technologies for 3 Early-Stage Researchers (ESRs), supported by a network of experts in anti-infective therapeutics, specifically virology and bacteriology in AiCuris, a pharmaceutical company; and the Institute of Chemical Research of Catalonia (ICIQ), a research Institute focused on sustainable chemistry in the field of catalysis and flow chemistry (through its technology development unit ERTFLOW). This ITN will educate the next generation of well-prepared ESRs, providing them with the skills necessary to pursue successful careers in a rapidly emerging field that requires novel multidisciplinary technological development as well as it will also be the channel for educating well-trained researchers with the scientific, technical and entrepreneurial skills so highly needed in the drug discovery field. This goal will be achieved through industrial doctoral training that includes international, interdisciplinary and inter-sectorial mobility, and that integrates both academic and industrial contributions. The research programme is composed of three closely related projects in the research areas of medicinal chemistry (including organic and computational chemistry), molecular biology and protein biochemistry.";743618,88;743618,88;H2020-MSCA-ITN-2017;/MSCA-ITN-EID;FUNDACIO PRIVADA INSTITUT CATALA D'INVESTIGACIO QUIMICA;ES;AICURIS ANTI-INFECTIVE CURES GMBH;DE;;1;0;0;1;0;0 207061;734713;SME 4.0;SIGNED;H2020-EU.1.3.3.;MSCA-RISE-2016;H2020;Industry 4.0 for SMEs - Smart Manufacturing and Logistics for SMEs in an X-to-order and Mass Customization Environment;2017-01-01;2020-12-31;;"Industry 4.0 refers to the fourth industrial revolution and technological evolution from embedded systems to cyber-physical systems (CPS) in production. The main objectives of Industry 4.0 can be summarized as the introduction of intelligent systems in production and logistics, the development of highly adaptable and modular manufacturing and logistics systems, the integration of sustainable and advanced manufacturing technologies as well as the promotion of automation technology and human-machine interaction. In the context of Industry 4.0 new ICT and web technologies act as booster or enabler of smart, autonomous and self-learning factories facing the challenges of even more individualized and customized product portfolio. A great challenge for the future lies in the transfer of Industry 4.0 expertise and technologies in small and medium sized enterprises (SME). SMEs represent the backbone of the economy and have an enormous importance in the development programs of the European Union for strengthening the competitiveness of European enterprises. Although the high potential of Industry 4.0 in SMEs, the main limit lies in a lack of concrete models for its implementation and application in small and medium enterprises. Thus, this research project titled “Industry 4.0 for SMEs - Smart Manufacturing and Logistics for SMEs in an X-to-order and Mass Customization Environment” aims to close and overcome this gap through the creation of an international and interdisciplinary research network. Identifying the needs and enablers for a smart and intelligent SME-Factory, creating adapted concepts and design solutions for production and logistics systems in SMEs and developing suitable organisation and business models will be the three main objectives of this research network. The applicability of the results is ensured through a close collaboration with a European small and medium sized enterprise (non-academic partner) from mass customization industry.";954000;783000;H2020-MSCA-RISE-2016;/MSCA-RISE;LIBERA UNIVERSITA DI BOLZANO;IT;"TECHNICKA UNIVERZITA V KOSICIACH;MONTANUNIVERSITAET LEOBEN;ELCOM, SPOLOCNOST S RUCENIM OBMEDZENYM, PRESOV";"SK;AT";;1;0;0;1;0;0 201679;713366;InterTalentum;SIGNED;H2020-EU.1.3.4.;MSCA-COFUND-2015-FP;H2020;Programme for Post-Doctoral Talent Attraction to CEI UAM+CSIC;2016-06-01;2021-05-31;;The Programme for Post-Doctoral Talent Attraction to CEI UAM\CSIC, InterTalentum, is a programme developed by the Universidad Autónoma de Madrid (UAM), which intends on building particularly favourable environment to attract the best experienced researchers in the four Focus Research Areas of CEI UAM\CSIC: Biology and Biomedicine, Nanoscience, Nanotechnology and Advanced Materials, Theoretical Physics and Mathematics and Social Sciences, Legal Sciences and Humanities. The program aims at exploiting the full potential of the CEI UAM\CSIC to offer the fellows a truly interdisciplinary and intersectorial training that will strengthen their curricula and provide the region of Madrid with a pool of researchers capable of preserving the long standing tradition for scientific excellence and bridging the gap between academic and applied research. Within the proposed 60 months co-funding period (48 months of fellowships), distributed in two International Calls, InterTalentum will offer to 18 incoming experienced researchers, of any nationality, the opportunity to develop her/his research project within the framework of a vast network of institutions participating under CEI UAM\CSIC, an International Excellence initiative and a Global Campus, including some worldwide reference research laboratories at Universidad Autónoma de Madrid (UAM, included its Joint Research Institutes and Health Institutes), Consejo Superior de Investigaciones científicas (CNB - Centro Nacional de Biotecnología, ICMM - Instituto de Ciencia de Materiales de Madrid, ICP - Instituto de Catálisis y Petroquímica , ICV - Instituto de Cerámica y Vidrio, IMM - Instituto de Microelectrónica de Madrid), Madrid Advanced Research Institutes “IMDEAS” (IMDEA – Alimentación, IMDEA Nanociencia). Researchers will be selected through a transparent and international evaluation process taking into consideration the whole range of experience of the candidates.;2548800;1274400;H2020-MSCA-COFUND-2015;/MSCA-COFUND-FP;UNIVERSIDAD AUTONOMA DE MADRID;ES;;;;1;0;0;1;0;0 213904;771168;ForceMorph;SIGNED;H2020-EU.1.1.;ERC-2017-COG;H2020;The integration of cell signalling and mechanical forces in vascular morphology;2018-03-01;2023-02-28;;"Cardiovascular diseases represent the principal worldwide medical challenge of the 21st century (WHO), and new concepts to treat, predict and even prevent these diseases are needed. Structural remodelling of the vasculature in response to changes in blood flow is important to maintain mechanical homeostasis, and many diseases are related to defects in tissue morphology and mechanical imbalance. Signalling between endothelial cells (ECs) and vascular smooth muscle cells (VSMCs) via the Notch pathway regulates the morphology and structural remodelling of the arterial wall. Importantly, Notch offers handles for therapeutic control and thus opportunities for treatment of malformation and adaptation. However, we lack the essential understanding of how hemodynamic forces integrate with Notch signalling to rationally and responsibly target Notch in vascular therapies. The complexity of the problem requires new tools and an interdisciplinary approach. Our project integrates engineering, computational modelling, with cell biology and in vivo model systems to address the question. In vivo models will validate the in in vitro model systems to ensure that they are reproducible and reflect the reality. Through this integrated approach we will enable new therapeutic developments. The specific objectives of the project are to: 1) Study EC-VSMC signalling real time, at high resolution by a novel biomimetic 4D Artery-on-Chip that recapitulates the cell-composition, -organisation and hemodynamic forces of the physiological artery. 2) Develop a computational model of the arterial wall that include the mechanosensitivity of Notch signalling to predict how the complex interactions affect arterial morphology and remodelling. 3) Use in vivo animal models to elucidate how regulation of Notch signalling affects tissue morphology and remodelling in response to changes in hemodynamic conditions.";1919599;1919599;ERC-2017-COG;/ERC-COG;ABO AKADEMI;FI;TECHNISCHE UNIVERSITEIT EINDHOVEN;NL;;1;0;0;1;0;0 205471;721383;PAM^2;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2016;H2020;Precision Additive Metal Manufacturing;2016-12-01;2020-11-30;;"Additive Manufacturing (AM) is a fast?growing sector with the ability to evoke a revolution in manufacturing due to its almost unlimited design freedom and its capability to produce personalised parts locally and with efficient material use. AM companies however still face technological challenges such as limited precision due to shrinkage and build?in stresses and limited process stability and robustness. Moreover often post?processing is needed due to the high roughness and remaining porosity. In addition qualified, trained personnel is hard to find. This ITN project will address both the technological and people challenges. To quality assure the parts produced, PAM? will, through a close collaboration between industry and academia, address each of the various process stages of AM with a view to implementing good precision engineering practice. To ensure the availability of trained personnel, ESRs will, next to their individual research and complementary skills training, be immersed in the whole AM production chain through hands?on workshops where they will design, model, fabricate, measure and assess a specific product. The expected impact of PAM? thus is: 1. The availability of intersectoral and interdisciplinary trained professionals in an industrial field that's very important for the future of Europe, both enhancing the ESR future career perspectives and advancing European industry. 2. The availability of high precision AM processes through improved layout rules with better use of AM possibilities, better modelling tools for first?time right processing, possibility for in?situ quality control ensuring process stability and, if still needed, optimised post?processing routes 3. As a result of 1: an increased market acceptance and penetration of AM. 4. Through the early involvement of European industry: a growing importance of the European industrial players in this fast?growing field. This will help Europe reach its target of 20% manufacturing share of GDP.";3944925,36;3944925,36;H2020-MSCA-ITN-2016;/MSCA-ITN-ETN;KATHOLIEKE UNIVERSITEIT LEUVEN;BE;"NUOVO PIGNONE SRL;LAYERWISE;ALICONA IMAGING GMBH;UNIVERSITA DEGLI STUDI DI PADOVA;KARLSRUHER INSTITUT FUER TECHNOLOGIE;DANMARKS TEKNISKE UNIVERSITET;THE UNIVERSITY OF NOTTINGHAM;LEGO SYSTEM AS;TECHNISCHE UNIVERSITEIT DELFT";"IT;BE;AT;DE;DK;UK;NL";;1;0;0;1;0;0 206131;708305;SIPEA;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Social Investment Perspective in Work-Family Reconciliation Measures in Europe and East Asia;2016-10-01;2018-09-30;;"This project aims to explore the effects of social investment perspective on women and to identify effective work-family reconciliation measures in fostering social inclusion of women in the labour market and family. It adopts a mixed method approach to compare the social investment perspective in the work-family reconciliation measures in five European and two East Asian countries (Sweden, Germany, Hungary, the UK, France, Hong Kong and South Korea); and examines its relationship with women’s participation in the production and reproduction spheres. Systematic comparison of policy designs with the aid of country based policy grids, statistical analysis under the economic defamilisation index and state-led care-focused defamilisation index, semi-structural interviews with policy experts, secondment in non-academic organisations and dissemination activities will be conducted. Against the backdrop of the Lisbon Agenda and Horizon 2020, the social investment perspective has become a new social policy paradigm in Europe. It stresses on investing in human capital development, making efficient use of human capital and fostering social inclusion. It shares similarities with the productive approach in some East Asian countries which is regarded as important to economic success. This project will enhance the researcher’s comparative social research skills and cross-regional knowledge on related policies; add value to the hosting university’s leadership in international social policy study; promote knowledge transfer between the two regions; and derive policy suggestions on social inclusion of women in the labour market and family. It is built on the expertise of the supervisor and the researcher on welfare policies in Europe and East Asia; and will be an integral part of the work plan of the interdisciplinary East Asian Social Policy Research Network and Social Policy Cluster of the hosting University. This is a project to be considered by the Reintegration Panel (RI).";195454,8;195454,8;H2020-MSCA-IF-2015;/MSCA-IF-EF-RI;THE UNIVERSITY OF SHEFFIELD;UK;;;;1;0;0;1;0;0 205897;695300;HKADeC;SIGNED;H2020-EU.1.1.;ERC-ADG-2015;H2020;Human Capital Accumulation in Developing Countries: Mechanisms, Constraints and Policies;2016-11-01;2021-10-31;;We propose to study the process of human capital accumulation during the early years of life in developing countries. The research is motivated by the importance of early years to human development, both because of the long run consequences of events during that period and because of high malleability across key developmental domains during that period, making it particularly salient for policy interventions. The research is organized into three parts. First, we need to understand the process of formation of human capital, what economists refer to as the production function of human capital. Human capital is understood as a multidimensional object whose components (cognition and intelligence, socio-emotional skills, health) evolve in a complex way interacting with a variety of inputs and environmental factors. Disentangling the role played by different factors and inputs (including initial conditions, environmental shocks, parental inputs, centre based care) is important for our understanding of the process and for policy analysis. Second, we need to understand parental behaviour, as parents choose many of the investments in human capital development. Many questions are open: what are the constraints (resources, information, beliefs and attitudes) that parents face in making investment choices? Do parents make optimal choices? Do parents reinforce or compensate shocks? How are resources allocated across children of different gender and/or ability? Who makes decisions within the family? Third, measurement and the design of measurement tools is central to our research. We need to examine the performance of existing measurement tools and propose, design and validate new ones. The research, led by an economist, is interdisciplinary, using inputs from psychologists, child development specialists, geneticists, anthropologists and is organized around a unified framework, whereupon parents make choices taking into account the production function and a number of constraints;1781278,75;1781278;ERC-2015-AdG;/ERC-ADG;Institute for Fiscal Studies;UK;;;;1;0;0;1;0;0 214152;795044;DYNAVOLC;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Transitions in Rheology and Volatile Dynamics of Magmas: Mapping the Window to Explosive Volcanism;2018-04-01;2021-06-16;;"The growing number of inhabitants, tourists, and economic activities near volcanoes, require adequate volcanic hazard-assessment and -mitigation plans to guide decision-making in the case of volcanic unrest. Especially the Campi flegrei caldera (Naples, Italy) is a significant threat to the EU, as a large scale eruption is foreseen within the coming century. Accurate forecasting of volcanic behaviour is hampered by a lack of understanding of the magmas transport properties. Changes in viscosity due to the interaction between primitive and evolved magmas are documented to trigger volcanic eruptions across the globe. In the past decades, two key transition zones in magma rheology were identified that separate effusive from explosive and eruptible from non-eruptible magmas: 1) solidification through crystallization and 2) fluidization through vesiculation. Even though these transition zones are identified and the computation capacities to forecast volcanic eruptions have grown exponentially over the past decades, none of the available computer models are able to produce coherent results and no model scenario is verified in nature. This is because predictive approaches rely on accurate rheological data, which are absent to date. Recent technological advances, in combination with a new, interdisciplinary research approach now allow us to address this knowledge gap. Measuring the evolution of magma viscosity across the two change zones is one of the most interesting challenges at the interface between geo- and material-sciences. This project aims to develop a systematic understanding of the evolution of rheological transition zones from magma chambers to super eruptions. The results allow more precise forecasting of volcanic eruptions and may find application in the glass and ceramic industries. The proposed research and training will set me up as an independent researcher who can lead a cutting-edge research group bridging the gap between geo- and material-sciences.";243352,8;243352,8;H2020-MSCA-IF-2017;/MSCA-IF-GF;LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN;DE;;;;1;0;0;1;0;0 206317;715154;AMORE;SIGNED;H2020-EU.1.1.;ERC-2016-STG;H2020;A distributional MOdel of Reference to Entities;2017-02-01;2022-01-31;;"'When I asked my seven-year-old daughter 'Who is the boy in your class who was also new in school last year, like you?', she instantly replied 'Daniel', using the descriptive content in my utterance to identify an entity in the real world and refer to it. The ability to use language to refer to reality is crucial for humans, and yet it is very difficult to model. AMORE breaks new ground in Computational Linguistics, Linguistics, and Artificial Intelligence by developing a model of linguistic reference to entities implemented as a computational system that can learn its own representations from data. This interdisciplinary project builds on two complementary semantic traditions: 1) Formal semantics, a symbolic approach that can delimit and track linguistic referents, but does not adequately match them with the descriptive content of linguistic expressions; 2) Distributional semantics, which can handle descriptive content but does not associate it to individuated referents. AMORE synthesizes the two approaches into a unified, scalable model of reference that operates with individuated referents and links them to referential expressions characterized by rich descriptive content. The model is a distributed (neural network) version of a formal semantic framework that is furthermore able to integrate perceptual (visual) and linguistic information about entities. We test it extensively in referential tasks that require matching noun phrases (“the Medicine student”, “the white cat”) with entity representations extracted from text and images. AMORE advances our scientific understanding of language and its computational modeling, and contributes to the far-reaching debate between symbolic and distributed approaches to cognition with an integrative proposal. I am in a privileged position to carry out this integration, since I have contributed top research in both distributional and formal semantics. '";1499805;1499805;ERC-2016-STG;/ERC-STG;UNIVERSIDAD POMPEU FABRA;ES;;;;1;0;0;1;0;0 199454;670628;SICLE;SIGNED;H2020-EU.1.1.;ERC-ADG-2014;H2020;Saadian Intellectual and Cultural Life;2016-02-01;2021-01-31;;"The aim of the interdisciplinary investigation project SICLE is to investigate in a completely new way the intellectual and cultural history of the Saadian period in Morocco (1554-1660), using primarily the Saadian sultans’ library, exceptionally preserved as a ‘time capsule’ in the El Escorial monastery following king Felipe III’s decision to include it in his own library. The period is a time of direct involvement of Morocco in international politics and exchanges, both in their East-West (with the Ottoman empire) and North-South (with Europe) dimensions, without forgetting Timbuktu and the Songhay empire conquered by Ahmad al-Mansur, the most brilliant ruler of the dynasty. The manuscripts kept in El Escorial mirror the interests and the tastes of the Saadian rulers and of the elite at large. The paratextual information they contain (but ignored by the catalogues) like the various notes, the colophons, the illuminations or the bindings will be systematically collected and analyzed in a trans-disciplinary approach which can be defined as an ‘archaeology of the book’, combining codicology, philology, archaeometry, anthropology and art history. The same approach will be applied to the books of the ‘ordinary people’ from Saadian times preserved in Moroccan collections. SICLE goals are to offer: a) a history of the Saadian sultans’ library and an analysis of their interests; b) a cultural and intellectual history of Morocco during the 16th century, with groundbreaking studies on the history of the book, on its economy and on education; c) an evaluation of the relationship with the ‘outside’ (Christian Europe, the Ottoman empire and sub-Saharan Africa) and the possible influence it had on Saadian intellectual production. Special attention will be paid to the Jewish and Morisco communities in their role of culture brokers.";1959283;1959283;ERC-2014-ADG;/ERC-ADG;COLLEGE DE FRANCE;FR;;;;1;0;0;1;0;0 196586;655710;CONRICONF;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2014-GF;H2020;Contentious Rights: A Comparative Study of International Human Rights Norms and their Effects on Domestic Social Conflict;2016-01-17;2020-02-08;;"Contentious Rights: A Comparative Study of International Human Rights Norms and their Effects on Domestic Social Conflict Over the last 60 years, a broad set of international norms gained importance as instruments to regulate a globalising world. Enshrined in human rights conventions, these norms contribute to strengthen a platform for social mobilization and voice. The introduction of human rights standards at the domestic level, however, has also been responsible for the generation of new tensions on the interpretation and application of these norms. Yet, this type of conflict and polarization among social and political actors remain widely unexplored. This project will examine how ‘human rights act in practice’ in the post-ratification phase using a multidisciplinary perspective and an empirical comparative approach. More precisely, it addresses the task of identifying the conditions under which international norms generate consensus and cooperation or fragmentation and conflict between domestic social and political actors and the consequences in terms of human rights practices. The candidate fellow Dr. Lorenza Fontana will focus on a comparative analysis of two conventions (International Labor Organization’s Conventions 182 on Child Labor and 189 on Domestic Workers) in two countries (Bolivia and Philippines) and lead an interdisciplinary collaboration between Prof. Jean Grugel (University of Sheffield, SIID), and Prof. Beth Simmons (Harvard University, WCFIA). This project will greatly increase our understanding of the effects of human rights norms on domestic societies and provide policy relevant results.";269857,8;269857,8;H2020-MSCA-IF-2014;/MSCA-IF-GF;UNIVERSITY OF NEWCASTLE UPON TYNE;UK;THE OPEN UNIVERSITY;UK;;1;0;0;1;0;0 206263;730427;COP21 RIPPLES;SIGNED;H2020-EU.3.5.1.;SC5-06-2016-2017;H2020;COP21: Results and Implications for Pathways and Policies for Low Emissions European Societies;2016-12-01;2019-11-30;;"The COP21 outcome represents an important new strategic context for EU climate policy. Analysing the implications of this new context requires an interdisciplinary approach, combining analysis of the evolution of the international climate regime as well as of NDCs and their socio-economic implications. Such analysis is also urgent, given the timelines imposed by the Paris Agreement for a “facilitative dialogue” in 2018 with a view to creating the conditions for the revision of NDC in 2020. In order to address the context described above, this project has four objectives : 1) Assess the adequacy of the NDCs submitted at COP21 in light of the global temperature target of limiting warming to 2°C/1.5°C. Through the analysis of GHG scenarios and energy system scenarios , the project will pay particular attention to the concrete system changes induced by NDCs, and compare them with the changes required to meet the global temperature limit. The project will also analyse scenarios limiting warming to 1.5°C, and the impact of NDCs on other sectors, in particular land-use. 2) Assess the implications of NDCs and deeper mitigation pathways on other European socio-economic objectives. By integrating GHG and energy system scenarios into a range of different macro-economic, global energy system models and other quantified methodologies, the project will investigate implications for European socio-economic objectives related to innovation and technology deployment; trade and competiveness; investment, financial flows and economic growth (“green growth”); and global energy markets and energy security. 3. Assess the adequacy of the outcomes of COP21, and the implications and opportunities emerging from ongoing UNFCCC negotiations. The project will undertake a social sciences-based (in particular international law and international relations) assessment of the outcome of COP21. 4) Policy recommendations for EU climate policy and climate diplomacy.";2986923,75;2986923,75;H2020-SC5-2016-OneStageB;/RIA;FONDATION INSTITUT DE RECHERCHE POUR LE DEVELOPPEMENT DURABLE ET LES RELATIONS INTERNATIONALES;FR;"UNIVERSITY OF EAST ANGLIA;THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;CLIMATE ANALYTICS GMBH;WISEEUROPA - FUNDACJA WARSZAWSKI INSTYTUT STUDIOW EKONOMICZNYCH I EUROPEJSKICH;BRUEGEL AISBL*;VRIJE UNIVERSITEIT BRUSSEL;SOFIISKI UNIVERSITET SVETI KLIMENT OHRIDSKI;TSINGHUA UNIVERSITY;UNIVERSITY OF CAPE TOWN;CLIMATE STRATEGIES;FUNDACAO COORDENACAO DE PROJETOS PESQUISAS E ESTUDOS TECNOLOGICOS COPPETEC;AGENZIA NAZIONALE PER LE NUOVE TECNOLOGIE, L'ENERGIA E LO SVILUPPO ECONOMICO SOSTENIBILE;WUPPERTAL INSTITUT FUR KLIMA, UMWELT, ENERGIE GMBH;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;FONDAZIONE CENTRO EURO-MEDITERRANEOSUI CAMBIAMENTI CLIMATICI;UNIVERSITY COLLEGE LONDON;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS";"UK;DE;PL;BE;BG;CN;ZA;BR;IT;FR";;1;0;0;1;0;0 194120;643955;MoreGrasp;CLOSED;H2020-EU.2.1.1.4.;ICT-22-2014;H2020;Restoration of upper limb function in individuals with high spinal cord injury by multimodal neuroprostheses for interaction in daily activities;2015-03-01;2018-05-31;;"More than half of the persons with spinal cord injuries (SCI) are suffering from impairments of both hands, which results in a tremendous decrease of quality of life (QoL) and represents a major barrier for inclusion in society. Functional restoration is possible with neuroprostheses based on functional electrical stimulation (FES). However, current systems are non-intelligent, non-intuitive open loop systems without sensory feedback. MoreGrasp aims at developing a multi-adaptive, multimodal user interface including brain-computer interfaces (BCIs) for intuitive control of a semi-autonomous motor and sensory grasp neuroprosthesis to support activities of daily living in individuals with SCI. With such a system a bilateral grasp restoration may become reality. The multimodal interfaces will be based on non-invasive BCIs for decoding of movements intentions with gel-less electrodes and wireless amplifiers. The neuroprosthesis will include FES electrode arrays and different sensors to allow for implementation of predefined or autonomously learned sequences. MoreGrasp will consequently follow the concept of the user-centered design by providing a scalable, modular, user-specific neuroprosthesis together with personalized EEG recording technology. Novel multimodal software architectures including interoperability standards will be defined to integrate neuroprostheses into the field of assistive technology. Long-term end user studies will demonstrate the reliability, usefulness and impact on QoL of the MoreGrasp technology. A web-based service infrastructure including a discussion forum will be set up for assessing user priorities and screening of users’ status. The evaluation of the training and patterns of use will allow for user modeling to identify factors for successful use. The highly interdisciplinary MoreGrasp consortium consists of members from universities, industry and rehabilitation centers, which have a long history of successful cooperation.";3471452,5;3471452,5;H2020-ICT-2014-1;/RIA;TECHNISCHE UNIVERSITAET GRAZ;AT;"Medel Medizinische Elektronic Handelsgesellschaft mbH;BIT & BRAIN TECHNOLOGIES SL;UNIVERSITAETSKLINIKUM HEIDELBERG;UNIVERSITY OF GLASGOW;KNOW-CENTER GMBH RESEARCH CENTER FOR DATA-DRIVEN BUSINESS & BIG DATA ANALYTICS";"DE;ES;UK;AT";;1;0;0;1;0;0 214787;779295;ImmunAID;SIGNED;H2020-EU.3.1.1.;SC1-PM-03-2017;H2020;Immunome project consortium for AutoInflammatory Disorders;2018-05-01;2023-04-30;;Systemic autoinflammatory diseases (SAID) encompass several rare disorders characterised by extensive clinical and biological inflammation. SAID are caused by the dysregulation of the innate immune system. Due to numerous and unspecific symptoms, tentative diagnosis often leads to failure/delay and inadequate treatments. ImmunAID will deliver a method for rapid and accurate diagnosis across all the spectrum of SAID, in order to improve clinical management of SAID patients. Thanks to parallel analyses run on samples from more than 600 patients with monogenic or undiagnosed SAID collected throughout Europe, Immunaid will generate a unique and comprehensive set of data, based on unbiased multiomics approaches (gene, transcript, protein, microbiome), and hypothesis-driven assays exploring inflammasome, inflammation resolution and immune networks. A centralised data management strategy will enable to conduct integrated analyses for diagnostic biomarker identification. In a discovery phase, semi-supervised clustering of omics data will be combined to supervised analysis of pathway-related data to provide robust classification and strong link to clinical features/impact. The related biomarkers will further be validated externally on independent samples and cohorts. Overall, ImmunAID will disentangle the spectrum of SAID, and propose a new omics- and pathogenesis-based SAID classification associated to a clinical decision making algorithm implementable in daily practice. An efficient dissemination plan will target e.g. guideline-forming bodies, the medical community and patients with the help of the ERN RITA and with the objective of turning our results into clinical practice. To further support this, proactive innovation management will be implemented. To reach its ambitious goals, ImmunAID interdisciplinary consortium gathers high-level partners, including the founder of SAID concept, experts in omics science, immunology, bioinformatics, and involves clinicians and patient advocacy groups.;15835851,25;15835851,25;H2020-SC1-2017-Single-Stage-RTD;/RIA;INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE;FR;"ECRIN EUROPEAN CLINICAL RESEARCH INFRASTRUCTURE NETWORK;WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER;UNIVERSITE DE LIEGE;FMF & AID GLOBAL ASSOCIATION;UNIVERSITE DE GENEVE;COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES;ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS;KOBENHAVNS UNIVERSITET;HOSPITAL SANT JOAN DE DÉU;UNIVERSITY OF LEEDS;IDRYMA IATROVIOLOGIKON EREUNON AKADEMIAS ATHINON;OWKIN FRANCE;INSTITUT CURIE;VIB;CENTRE HOSPITALIER UNIVERSITAIRE DE LIEGE;HACETTEPE UNIVERSITESI;PANEPISTIMIO IOANNINON;ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM;UNIVERZITETNI KLINICNI CENTER LJUBLJANA;UNIVERSITY COLLEGE LONDON;KATHOLIEKE UNIVERSITEIT LEUVEN;AMBIOTIS;OSPEDALE PEDIATRICO BAMBINO GESU";"FR;DE;BE;CH;DK;ES;UK;EL;TR;NL;SI;IT";;1;0;0;1;0;0 214785;778388;FODIAC;SIGNED;H2020-EU.1.3.3.;MSCA-RISE-2017;H2020;Foods for diabetes and cognition;2018-04-01;2022-03-31;;"FODIAC aims to develop a dietary solution to tackle type 2 diabetes and cognitive dysfunction of the elderly. FODIAC will enhance the quality of R&I in Europe, promoting cooperation along the Food Value Chain. This is achieved through advanced international, intersectoral, cooperation between 7 academic and 8 industry partners. For this purpose, FODIAC assembles a European multi/interdisciplinary consortium, composed of partners in 5 countries that provide expertise in: extraction and purification of bioactive molecules, nanotechnology, nano/micro-encapsulation, toxicology, nutrition, biomarkers, clinical trial management. Rationale: lack of knowledge sharing among academia and industry acts as a barrier for the development of functional foods for the elderly, who represent one of the fastest-growing population segments worldwide. Approach and Outcomes: FODIAC coordinates the actions of individual partners, academic and industrial, using Exchange of Staff as a tool to capitalize on complementary competences to: i) conduct joint research; ii) protect the Intellectual Property based on this research; iii) foster the transference of the generated knowledge, skills, and technology to the industrial sector; and iv) exploit research output to the benefit of society. FODIAC’s outcomes will include: i) an increase in the R&I capacity among participating partners; ii) boosting of knowledge transfer of emerging micro/nano-biotechnologies from academia to industry, to develop cost-effective processes; iii) commercialization of new functional ingredients and functional foods containing antidiabetic and cognitive-enhancing bioactive molecules; iv) acceleration of the development of dietary recommendations and interventions based on those products, to improve the quality of life of the elderly; iv) a sustainable research network of academic and industrial partners and v) the leveraging of career perspectives of individual researchers, both in and outside academic institution";432000;432000;H2020-MSCA-RISE-2017;/MSCA-RISE;LABORATORIO IBERICO INTERNACIONAL DE NANOTECNOLOGIA;PT;"UNIVERSIDADE DO MINHO;BIOINICIA SL;LUNDS UNIVERSITET;THE UNIVERSITY OF READING;GERIATROS SA;SONAE MC - SERVICOS PARTILHADOS, SA;ASOCIACION NACIONAL DE FABRICANTES DE CONSERVAS DE PESCADOS Y MARISCOS-CENTRO TECNICO NACIONAL DE CONSERVACION DE PRODUCTOS DE LA PESCA;UNIVERSIDADE CATOLICA PORTUGUESA;AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS;EVRA SRL;DECORGEL PRODUTOS ALIMENTARES SA;BUCALOSSI ALESSANDRO;A&R HOUSE (BCL) LTD;UNIVERSITA CATTOLICA DEL SACRO CUORE";"PT;ES;SE;UK;IT";;1;0;0;1;0;0 214539;794766;DYNOS;CLOSED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;The coupled dynamics of Southern Ocean climate change;2018-09-03;2020-09-02;;"As a major sink of both heat and carbon dioxide, the Southern Ocean plays a crucial role in the trajectory of global climate change. However, Southern Ocean climate is highly complex and perturbed by both rising greenhouse gas concentrations and ozone depletion. Contemporary climate models vary greatly in their representations of the current and future climate of the Southern Ocean, limiting our ability to produce reliable climate predictions. To address this issue, this proposal takes a novel interdisciplinary approach, integrating stratosphere-troposphere-ocean-sea ice interactions. It aims to answer the following questions: (1) What mechanisms control the time-dependent coupled response of the Southern Ocean to anthropogenic forcing? (2) How do uncertainties in the response depend on models’ representation of key physical processes? (3) How far can observational estimates reduce model uncertainties in SO climate projections? The project will make use of a range of newly-available observations of the Southern Ocean, as well as perform a suite of simulations with the state-of-the-art UK Earth System Model (UKESM). Close links will be maintained with modelling groups to ensure that the results of this project feed into the development of the next generation of climate models. This action will also include knowledge transfer between the atmospheric science and oceanography communities, as well as the generation of a publicly available ensemble of “Climate Response Function” simulations, which will be a vital resource for the community. This fellowship will allow the Researcher to gain important new knowledge in both oceanic and atmospheric dynamics by working with world-leading experts in these fields. It will provide skills in the use of state-of-the-art UK and European climate models and spur multiple new research opportunities, enabling the Researcher to stay at the forefront of climate research and acting as a stepping stone towards a leadership position.";183454,8;183454,8;H2020-MSCA-IF-2017;/MSCA-IF-EF-RI;THE UNIVERSITY OF READING;UK;;;;1;0;0;1;0;0 214552;798866;EcoLabSS;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Ecovillages as Laboratories of Sustainability and Social Change;2018-09-10;2021-04-07;;"In an historical moment where citizens of the world are called to take action to face ´multiple crises´- the emergency of climatic change, high and rising socio-economic inequalities, and the upsurge of intolerance and racism within and between countries - the study of transformative grassroots initiatives becomes crucially important and timely. ‘Ecovillages as Laboratories of Sustainability and Social Change´ (EcoLabSS) is conceived as an international, inter-sectoral and interdisciplinary project aiming at producing a theoretically grounded and methodologically innovative study of one of these grassroots initiatives: the ecovillage movement. EcoLabSS provides a multi-level and mixed-method study of the ecovillage movement that combines the comparative study of two local ecovillages, respectively in Denmark and Italy, with a systematic analysis of the actions and networks of the transnational organization Global Ecovillage Network (GEN). The review and the fieldwork is then used to develop a comprehensive theoretical and analytical framework centred on the path-breaking definition of ´community-based prefigurative social movements´. The empirical analysis is structured along three mutually informing levels of analysis: micro-individual level, meso-community level, and macro-societal level. The first level is focused on the study of individual life trajectories and biographies of ecovillage inhabitants. The meso-community level is analyzing the everyday practices and processes involving organization, decision-making and creation of future-oriented norms and codes of conduct inside the two case studies. Finally, the macro-societal level is centred on the study of how the ecovillage movement - represented by the transnational organization GEN - translates and diffuses its practices, narratives and visions of a just and sustainable society to policy-makers, institutions, other civil society actors and the wider public.";200194,8;200194,8;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;COPENHAGEN BUSINESS SCHOOL;DK;;;;1;0;0;1;0;0 208794;721403;SLATE;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2016;H2020;Submarine LAndslides and Their impact on European continental margins;2017-04-01;2021-03-31;;"The over-arching aim of the SLATE ETN is (i) to understand key factors triggering submarine landslides, the subsequent motion and evolution of failed material, and ensuing geohazards eg tsunamis and (ii) to integrate an innovative broad range of scientific disciplines and private sector needs into a novel training and co-supervision of 15 ESRs. SLATE will focus on investigating submarine landslides and associated geohazards as important natural risks that threaten offshore infrastructures and coastal regions in Europe. Submarine landslides can move much longer than any slope failure on land, and occur on remarkably low gradients, suggesting fundamental and still poorly understood differences from onshore counterparts. A wide spectrum of tectonic and marine environmental settings needs to be investigated. To master this holistic approach, SLATE will bring together a world-class team of leading experts from renowned academic institutions and key non-academic partners with an unusually comprehensive set of interdisciplinary expertise. This ETN comprises experts with outstanding backgrounds in marine geophysics, sedimentology, civil engineering, geotechnics, tsunami research, and hazard assessment as well as marine technology. SLATE partners offer excellent datasets and skills that include field observations, lab experiments, as well as analytical, mathematical and numerical modelling techniques. Training will cover various geoscientific methods, as well as assessment of consequences and impacts on coastal regions and society. Together with various transferable and complementary courses skilled in SLATE, this integrative approach will guide the research of all projects to train a new generation of highly motivated and excellent qualified young scientists to tackle challenges linked to landslide-initiated hazards. SLATE will cover European-wide project with 10 beneficiaries from academia and non-academia (incl. industry) and 4 partner organizations from 6 countries.";3894543,36;3894543,36;H2020-MSCA-ITN-2016;/MSCA-ITN-ETN;UNIVERSITAET BREMEN;DE;"UNIVERSITY OF DURHAM;CONTROL Y PROSPECCIONES IGEOTEST SL;CHRISTIAN-ALBRECHTS-UNIVERSITAET ZU KIEL;AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS;UNITED KINGDOM RESEARCH AND INNOVATION;CONSIGLIO NAZIONALE DELLE RICERCHE;ISTITUTO NAZIONALE DI OCEANOGRAFIA E DI GEOFISICA SPERIMENTALE;STIFTELSEN NORGES GEOTEKNISKE INSTITUTT;INSTITUT FRANCAIS DE RECHERCHE POUR L'EXPLOITATION DE LA MER;UNIVERSITAET INNSBRUCK;NATURAL ENVIRONMENT RESEARCH COUNCIL";"UK;ES;DE;IT;NO;FR;AT";;1;0;0;1;0;0 207196;731473;QuantERA;SIGNED;H2020-EU.1.2.2.;FETPROACT-03-2016;H2020;QuantERA ERA-NET Cofund in Quantum Technologies;2016-11-01;2021-10-31;;"QuantERA ERA-NET Cofund in Quantum Technologies Quantum Technologies (QT) has become a new and fast developing area of research initiated by a realisation that quantum physics opens up radically new modes of quantum information processing and communication. European researchers have been at the forefront of these developments delivering many groundbreaking scientific results and advancing technological exploitation. The need to reinforce European excellence in QT and the highly interdisciplinary nature of QT call out for an integrated Europe-wide approach to support research efforts in this area. The central objective of the QuantERA Programme involving 31 agencies is to launch a transnational Co-funded Call that will cover 26 countries. The planned budget of this funding opportunity amounts to 25 590 000 EUR of national contributions. It is expected that the EC will allocate an additional EUR 11.5 million to the Co-funded Call budget and other project tasks. Launching a Co-funded Call will be complemented by a range of additional activities aimed at stimulating cooperation within the research community, creating and maintaining links between academia and industry, building a toolkit on responsible research and innovation in QT, exchanging best practices, and engaging in a dialogue with policy makers about the design of future funding instruments. The QuantERA proposal conforms to the specific challenges and scope of the Work Programme Horizon 2020-Future and Emerging Technologies for 2016-2017 by providing a structured framework to coordinate national and regional research programmes in the QT. In accordance with the Work Programme, the scientific scope of the QuantERA Call will focus on new technologies facilitated by specific quantum phenomena such as superposition states, the no cloning rule, or entanglement to achieve new or radically enhanced functionalities.";39783228;11510008,29;FETPROACT-2016;/ERA-NET-Cofund;NARODOWE CENTRUM NAUKI;PL;"MINISTRY OF EDUCATION YOUTH AND SPORTS;NEMZETI KUTATASI FEJLESZTESI ES INNOVACIOS HIVATAL;BULGARIAN NATIONAL SCIENCE FUND;GENIKI GRAMMATIA EREVNAS KAI TECHNOLOGIAS;FONDS ZUR FÖRDERUNG DER WISSENSCHAFTLICHEN FORSCHUNG;Unitatea Executiva pentru Finantarea Invatamantului Superior, a Cercetarii, Dezvoltarii si Inovarii;TURKIYE BILIMSEL VE TEKNOLOJIK ARASTIRMA KURUMU;MINISTERO DELL'ISTRUZIONE, DELL'UNIVERSITA' E DELLA RICERCA;VETENSKAPSRADET - SWEDISH RESEARCH COUNCIL;INNOVATIONSFONDEN;BUNDESMINISTERIUM FUER BILDUNG UND FORSCHUNG;VALSTS IZGLITIBAS ATTISTIBAS AGENTURA;MINISTERIO DE ECONOMIA, INDUSTRIA Y COMPETITIVIDAD;SUOMEN AKATEMIA;VDI TECHNOLOGIEZENTRUM GMBH;UNITED KINGDOM RESEARCH AND INNOVATION;MATIMOP, ISRAELI INDUSTRY CENTER FOR RESEARCH & DEVELOPMENT;CONSIGLIO NAZIONALE DELLE RICERCHE;SCIENCE FOUNDATION IRELAND SFI;NORGES FORSKNINGSRAD;SCHWEIZERISCHER NATIONALFONDS ZUR FORDERUNG DER WISSENSCHAFTLICHEN FORSCHUNG;The Technology Strategy Board;THE ENGINEERING AND PHYSICAL SCIENCES RESEARCH COUNCIL;SLOVENSKA AKADEMIA VIED;STICHTING NEDERLANDSE WETENSCHAPPELIJK ONDERZOEK INSTITUTEN;AGENCE NATIONALE DE LA RECHERCHE;Ministrstvo za izobrazevanje, znanost in sport;NARODOWE CENTRUM BADAN I ROZWOJU;FONDS VOOR WETENSCHAPPELIJK ONDERZOEK-VLAANDEREN;FONDS NATIONAL DE LA RECHERCHE SCIENTIFIQUE;OESTERREICHISCHE FORSCHUNGSFOERDERUNGSGESELLSCHAFT MBH;FUNDACAO PARA A CIENCIA E A TECNOLOGIA";"CZ;HU;BG;EL;AT;RO;TR;IT;SE;DK;DE;LV;ES;FI;UK;IL;IE;NO;CH;SK;NL;FR;SI;PL;BE;PT";;1;0;0;1;0;0 205960;724363;DIAL;SIGNED;H2020-EU.3.6.1.2.;REV-INEQUAL-03-2016;H2020;Dynamics of Inequality Across the Life-Course: structures and processes;2016-11-01;2021-10-31;;"Existing and rising inequalities pose fundamental challenges to European societies and economies. Large disparities in human and social capacities are counterproductive to a sustainable and creative economy and participatory governance and inclusion. The increasing gulf between rich and poor, exacerbated by the recent financial and economic crises, is a key concern. The sources of inequalities in contemporary societies are complex and highly intertwined and they and their consequences can only be understood through comprehensive, comparative and innovative research activities. It is for this reason that the NORFACE Network is committed to launch a transnational research programme on the topic of Dynamics of Inequality Across the Life-course: structures and processes (DIAL). The DIAL programme will contribute to understanding the dynamics of inequalities as they unfold over the life-course, causal processes and drivers in relation to these inequalities, the role of time with regard to inequalities and the impact of these inequalities on social cohesion. The specific challenge of this Call is to address the dynamics comparatively in their social, cultural, economic and political dimensions and to disentangle the impact of past events and current circumstances on later outcomes to provide solutions to reverse inequalities across the life-course. The NORFACE DIAL programme will coordinate the research efforts of the participating European Member States by implementing a joint trans-national call with European Commission co-funding to fund innovative comparative, transnational and interdisciplinary research initiatives within this thematic field. The NORFACE Network has received core funding under the European Union’s ERA-Net scheme since 2004 and has developed a close partnership of European national agencies responsible for funding research activities in the social sciences. The DIAL programme builds on the successes of the NORFACE Network.";15817515,15;5000000;H2020-SC6-REV-INEQUAL-2016;/ERA-NET-Cofund;NEDERLANDSE ORGANISATIE VOOR WETENSCHAPPELIJK ONDERZOEK;NL;"STYRELSEN FOR FORSKNING OG UDDANNELSE;FONDS ZUR FÖRDERUNG DER WISSENSCHAFTLICHEN FORSCHUNG;THE ICELANDIC CENTRE FOR RESEARCH;ECONOMIC AND SOCIAL RESEARCH COUNCIL;Lietuvos mokslo taryba;DEUTSCHE FORSCHUNGSGEMEINSCHAFT;VETENSKAPSRADET - SWEDISH RESEARCH COUNCIL;JAVNA AGENCIJA ZA RAZISKOVALNO DEJAVNOST REPUBLIKE SLOVENIJE;AKADEMIE VED CESKE REPUBLIKY;SUOMEN AKATEMIA;NARODOWE CENTRUM NAUKI;UNITED KINGDOM RESEARCH AND INNOVATION;NORGES FORSKNINGSRAD;SCHWEIZERISCHER NATIONALFONDS ZUR FORDERUNG DER WISSENSCHAFTLICHEN FORSCHUNG;AN TUDARAS UM ARD OIDEACHAS;AGENCE NATIONALE DE LA RECHERCHE;FUNDACAO PARA A CIENCIA E A TECNOLOGIA";"DK;AT;IS;UK;LT;DE;SE;SI;CZ;FI;PL;NO;CH;IE;FR;PT";;1;0;0;1;0;0 205526;721484;Train2Target;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2016;H2020;An integrated mulTidisciplinary appRoach towards a new generAtIon of aNtibiotics: Targeting function and cross-talk of bacterial Envelope proTein machineries;2017-01-01;2020-12-31;;"Train2Target is a multidisciplinary European Training Network built to address the challenge of the discovery of alternative antimicrobials. Innovative strategies to deliver a next generation of drugs are urgently needed. The alarming threats and spread of multi-drug resistant bacteria is currently leaving clinicians with very limited options to combat infections especially those from Gram-negative pathogens. The Train 2Target research programme focuses on the assembly of the well-known bacterial cell envelope from a new perspective. Indeed it aims to inhibit novel targets in envelope biogenesis by altering the function and misbalancing the coordination of envelope assembly machines, which build and assemble the Gram-negative bacterial envelope. A wide variety of chemical classes and compounds sources will be screened using innovative biochemical, biophysical and genetic assays to identify valuable hit scaffolds to be optimized into druggable leads. The high quality and credibility of our consortium is ensured by a strong interdisciplinary academia-industry partnership to encompass different complementary expertise ranging from microbiology, bacterial genetics, biochemistry, cell imaging, structural biology, biophysics and chemical synthesis. Our 9 academic groups are all renowned leaders in the cell envelope biogenesis field, whereas the complementary 5 SMEs and 3 Industry partners are specialised in drug discovery and development of novel anti-infective drugs. This unique combination of scientific excellence and industrial know-how in drug discovery covers the entire process from the design to the implementation of innovative antibacterial strategies and lead identification. Train2Target also represents a unique research platform to train 15 Early Stage Researchers and equip them with the necessary scientific and transferable skills that will make them highly competitive for both top European research institutions and the pharma/biotech job market.";3931378,2;3931378,2;H2020-MSCA-ITN-2016;/MSCA-ITN-ETN;UNIVERSITA DEGLI STUDI DI MILANO;IT;"UNION THERAPEUTICS AS;THE UNIVERSITY OF BIRMINGHAM;UNIVERSITA DEGLI STUDI DI NAPOLI FEDERICO II;BIOVERSYS AG;UNIVERSITY OF NEWCASTLE UPON TYNE;UNIVERSITE CATHOLIQUE DE LOUVAIN;AICURIS ANTI-INFECTIVE CURES GMBH;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;UNIVERSITEIT VAN AMSTERDAM;NAICONS SRL";"DK;UK;IT;CH;BE;DE;FR;NL";;1;0;0;1;0;0 205439;722779;Training4CRM;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2016;H2020;European Training Network for Cell-based Regenerative Medicine;2016-11-01;2020-10-31;;"The main objective of Training4CRM is to train a new generation of 15 highly inter-disciplinary early stage researchers at the highest international level and quality, who will be immediately employable in both the academic and industrial sectors due to their highly sought after cross- and interdisciplinary insights and expertise. Training4CRM addresses existing gaps within Cell-based Regenerative Medicine for treatment of neurodegenerative disorders (e.g. Parkinson´s, Huntington´s, Epilepsy), which occur as a result of progressive loss of structure, function and/or death of neurons in the brain. The disorders have a high prevalence and are associated with impairments and disabilities with high emotional, financial and social burden. New scientific discoveries and technologies are needed, and Training4CRM sets out with the ambition to educate and train students within and across different scientific disciplines to be able to master the design, fabrication and testing of completely new tools and materials within the fields of: Micro- and Nanoengineering (nano/microstructures, 3D scaffolds and 3D lab-on-a-chip devices of different materials, geometries, architectures and properties, wireless electronic components; Biotechnology (human stem cells, human induced pluripotent stem cells, optogenetics, tissue engineering; Pre-clinical studies for the purpose of investigating in vivo, in experimental animals, how the developed cells, materials, structures affect the animal at the physiological and behavioral levels, unravelling the therapeutic effects of the developed strategies.";4028783,4;4028783,4;H2020-MSCA-ITN-2016;/MSCA-ITN-ETN;DANMARKS TEKNISKE UNIVERSITET;DK;"BIOMODICS APS;LUNDS UNIVERSITET;VERIGRAFT AB;FELIXROBOTICS BV;UNIVERSITAT DE BARCELONA;UNIVERSITETET I OSLO;POLITECNICO DI MILANO;UNIVERSIDAD AUTONOMA DE MADRID";"DK;SE;NL;ES;NO;IT";;1;0;0;1;0;0 197503;649021;BIOMENDELIAN;SIGNED;H2020-EU.1.1.;ERC-CoG-2014;H2020;Linking Cardiometabolic Disease and Cancer in the Level of Genetics, Circulating Biomarkers, Microbiota and Environmental Risk Factors;2015-09-01;2020-08-31;;"Cardiovascular disease (CVD), type 2 diabetes (T2D) and obesity, collectively referred to as cardiometabolic disease, together with cancer are the major morbidities and causes of death. With few exceptions, research on cardiometabolic disease and cancer is funded, studied and clinically applied separately without fully taking advantage of knowledge on common pathways and treatment targets through interdisciplinary synergies. The purpose of this proposal is to reveal causal factors connecting and disconnecting cardiometabolic diseases and cancer, and to understand interactions between gut microbiota, host diet and genetic susceptibility in a comprehensive prospective cohort study design to subsequently allow design of intervention strategies to guide more personalized disease prevention. 1. We investigate causality between genetic risk factors for cardiometabolic disease associated traits and future incidence of T2D, CVD, cancer (total/breast/colon/prostate) and mortality (total, CVD- and cancer mortality), searching for causal factors in a prospective cohort with >15 y follow-up (N>30,000, incident cases N=3550, 4713, 5975, 6115 for T2D, CVD, cancer, mortality) 2. For the first time in a large population (N=6000), we investigate how gut and oral microbiome are regulated by dietary factors, gut satiety peptides and host genetics, and how such connections relate to cardiometabolic disease associated traits and cancer 3. We investigate the role of diet and gene-diet interactions of importance for cardiometabolic disease and cancer 4. We perform genotype, biomarker and gut microbiota based diet intervention studies. This inter-disciplinary project contributes to biological understanding of basic disease mechanisms and takes steps towards better possibilities to prevent and treat individuals at high risk for cardiometabolic disease, cancer and death.";2000000;2000000;ERC-2014-CoG;/ERC-COG;LUNDS UNIVERSITET;SE;;;;1;0;0;1;0;0 195077;655240;Terra-Micro-Carbo;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Effect of land use induced shifts in soil microbial diversity and function on carbon cycling in soil;2015-07-14;2017-07-13;;"The need for improved food production for the growing population has led to increase in planet’s arable land cover. Many studies suggest that such practices lead to loss of soil organic carbon (C) – a relatively large C pool with a fast response time. Thus there is a need to manage soils sustainably in order to mitigate atmospheric CO2 levels while maintaining agricultural productivity. Soil microorganisms act as gatekeepers for soil-atmosphere C exchange by regulating the storage and release of organic C in soil. However, there is a lack of understanding on how land use induced shifts in soil microbial diversity affects this regulation; necessitating detailed research on the underpinning microbial mechanisms. The project objective is to discern the effects of land use on microbial diversity in differing soil types and to investigate whether this shift has implications for C cycling (do certain microbial groups have a greater capacity for soil C accumulation?). To address these objectives an interdisciplinary approach merging molecular biology and isotope chemistry will be employed. Soil from long-term grassland-arable paired sites will be used to assess differences in microbial biodiversity and functional gene abundance through DNA next-generation sequencing. In addition, a field incubation experiment with 13C labelled substrates will be performed to investigate the variable tracer incorporation into different microbial functional groups. This will be measured using novel magnetic bead capture hybridization of RNA from specific groups followed by its 13C analysis using liquid chromatography-isotope ratio mass spectrometry. The novelty of this project is that it aims to provide direct evidence to prove diversity-function linkages and gain mechanistic understanding of the physiological responses of soil microbial communities to land use change. The resulting knowledge will help better predict changes in soil C and thus improve prognosis of climate change feedbacks.";183454,8;183454,8;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;UNITED KINGDOM RESEARCH AND INNOVATION;UK;;;;1;0;0;1;0;0 200229;696231;SusAn;SIGNED;H2020-EU.3.2.;ISIB-12e-2015;H2020;European Research Area on Sustainable Animal Production Systems;2016-03-01;2021-02-28;;"This proposal seeks funding under the Horizon 2020 Work Programme 2014-2015 to establish an ERA-NET for joint European research coordination on Sustainable Animal Production (SusAn). The scope for this ERA-NET has been developed under the SCAR Collaborative Working Group on Sustainable Animal Production (CWG-SAP). Funding organisations from 22 European countries initially seek to support one co-funded call followed by other joint activities including the development of a Common Strategic Research and Innovation Agenda on Sustainable Animal Production. The animal production sector forms an important part of Europe’s (agricultural) economy and plays an essential role in the provision of Europe`s citizens with high quality animal products. Like other agriculture sectors, animal production faces many challenges from projected increases in global demand for food, climate change, competition for natural resources and economic volatility. The European animal production landscape is very complex, consisting of different species farmed within a wide range of different extensive, semi-intensive and intensive production systems using multiple resources to produce a diverse range of animal products and other services. Partners in this ERA-NET believe, however, that these challenges and complexities can be effectively addressed through joint European research within a framework which supports the three pillars of sustainability - economy, environment and society - and targets opportunities for innovative research spanning all areas of animal production such as health and welfare, feeding and nutrition, reproduction, breeding and genetics, housing, nutrient management and economics. Partners in ERA-NET SusAn endorse scientific excellence and recommend an integrated, interdisciplinary, cross-cutting and multi-actor approach to research and knowledge exchange which reflects the complexity of the research requirements for sustainable European animal production.";15983750;5000000;H2020-ISIB-2015-1;/ERA-NET-Cofund;Bundesanstalt für Landwirtschaft und Ernährung;DE;"NEDERLANDSE ORGANISATIE VOOR WETENSCHAPPELIJK ONDERZOEK;MAAELUMINISTEERIUM;FONDS FLANKEREND ECONOMISCH EN INNOVATIEBELEID;CENTRO PARA EL DESARROLLO TECNOLOGICO INDUSTRIAL.;ELIKA NEKAZARITZAKO ELIKAGAIEN SEGURTASUNARAKO EUSKAL FUNDAZIOA;MINISTERSTVO PODOHOSPODARSTVA A ROZVOJA VIDIEKA SLOVENSKEJ REPUBLIKY;THE SECRETARY OF STATE FOR ENVIRONMENT, FOOD AND RURAL AFFAIRS;MINISTRY OF AGRICULTURE AND FORESTRY;ELLINIKOS GEORGIKOS ORGANISMOS - DIMITRA;FORSCHUNGSZENTRUM JULICH GMBH;MINISTERO DELLE POLITICHE AGRICOLE ALIMENTARI E FORESTALI;MINISTRSTVO ZA KMETIJSTVO GOZDARSTVO IN PREHRANO;TURKIYE BILIMSEL VE TEKNOLOJIK ARASTIRMA KURUMU;SERVICE PUBLIC DE WALLONIE;INSTITUTO NACIONAL DE INVESTIGACION Y TECNOLOGIA AGRARIA Y ALIMENTARIA OA MP;VALSTS IZGLITIBAS ATTISTIBAS AGENTURA;MINISTERIE VAN ECONOMISCHE ZAKEN EN KLIMAAT;MINISTERIO DE ECONOMIA, INDUSTRIA Y COMPETITIVIDAD;EIGEN VERMOGEN VAN HET INSTITUUT VOOR LANDBOUW- EN VISSERIJONDERZOEK;FORSKNINGSR?DET FÖR MILJÖ, AREELLA NÄRINGAR OCH SAMHÄLLSBYGGANDE;LIETUVOS SVEIKATOS MOKSLU UNIVERSITETAS;TEAGASC - AGRICULTURE AND FOOD DEVELOPMENT AUTHORITY;UNITED KINGDOM RESEARCH AND INNOVATION;NORGES FORSKNINGSRAD;Bundesministerium für Ernährung, Landwirtschaft und Verbraucherschutz;LIETUVOS RESPUBLIKOS ZEMES UKIO MINISTERIJA;BIOTECHNOLOGY AND BIOLOGICAL SCIENCES RESEARCH COUNCIL;VLAAMSE GEWEST;Ministry of Food, Agriculture and Fisheries, Danish AgriFish Agency;DEPARTMENT OF AGRICULTURE, FOOD AND THE MARINE;BUNDESMINISTERIUM FUER NACHHALTIGKEIT UND TOURISMUS;INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE;MINISTERO DELLA SALUTE;SLOVENSKA AKADEMIA VIED;AGENCE NATIONALE DE LA RECHERCHE;NARODOWE CENTRUM BADAN I ROZWOJU;FUNDACAO PARA A CIENCIA E A TECNOLOGIA";"NL;EE;BE;ES;SK;UK;FI;EL;DE;IT;SI;TR;LV;SE;LT;IE;NO;DK;AT;FR;PL;PT";;1;0;0;1;0;0 198112;676027;SYSTEM-RISK;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2015-ETN;H2020;A Large-Scale Systems Approach to Flood Risk Assessment and Management;2016-01-01;2019-12-31;;Flood risk systems are characterised by physical and socio-economic processes acting at different space-time scales, by non-stationary and non-linear behaviour, and by a significant degree of interdependence between processes. This may lead to surprising developments and unanticipated side effects of risk reduction measures. A novel systems approach is needed that captures this dynamics and accounts for the interactions of the system components. We propose the ETN SYSTEM-RISK which aims at developing this systems approach for large spatial scales, from large river basins to the European scale. The research concept of SYSTEM-RISK builds upon the entire risk chain, from the source of hazard to consequences, and analyses the interactions and temporal dynamics in flood risk systems. In this way, the linear risk chain is replaced by a more realistic approach with interdependent links. SYSTEM-RISK exposes early-stage researchers (ESR) to all knowledge domains along the risk chain, and gives them, at the same time, the opportunity to build specific research profiles. The interdisciplinary setting and the focus on interactions and spatio-temporal dynamics of risk system will expand the mental models and lead to a new generation of creative scientists, able to transfer their systems perspective from flood risk systems to other fields. We bring together internationally leading groups in flood research with institutions from the non-academic main sectors exploiting flood research – consultancy, insurance industry and governmental sector. Close interaction will support the ESRs in developing trans-disciplinary skills with an understanding of both fundamental science and application. SYSTEM-RISK will deliver a suite of methods and tools for assessing and managing flood risk across large regions. This will be of highest importance for the EU Flood Directive and Strategy on Adaptation for Climate Change due to the EU’s key role in dealing with risks transcending national borders.;3884131,08;3884131,08;H2020-MSCA-ITN-2015;/MSCA-ITN-ETN;HELMHOLTZ ZENTRUM POTSDAM DEUTSCHESGEOFORSCHUNGSZENTRUM GFZ;DE;"FUTUREWATER BV;TECHNISCHE UNIVERSITAET WIEN;GECOSISTEMA SRL;HR WALLINGFORD LIMITED;STICHTING DELTARES;UNIVERSITY OF BRISTOL ROYAL CHARTER;ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA;UMWELTBUNDESAMT;MIDDLESEX UNIVERSITY HIGHER EDUCATION CORPORATION";"NL;AT;IT;UK;DE";;1;0;0;1;0;0 199306;699538;ESOF2016;SIGNED;H2020-EU.5.;SCIENCE WAF SOCIETY;H2020;EuroScience Open Forum 2016 (Manchester);2015-07-01;2016-10-31;;"The broad aim of this proposal is to advance the Horizon 2020 aims embodied in the Science WAF Society programme by organising the EuroScience Open Forum (ESOF). As Europe’s largest science communication event this will support the programme aims of addressing European societal challenges, building capacities and developing innovative ways of connecting science to society. It will promote the concept of responsible research and innovation in the context of Horizon 2020 and the ERA. Engagement will be sought from the full range of stakeholders including researchers, citizens, policy makers, business, third sector organisations and others. First held in Stockholm in 2004, ESOF is a biennial, interdisciplinary, pan-European, general science meeting taking place in a major European city, which aims to showcase the latest advances in scientific research and innovation; promote dialogue on the role of S&T in society and public policy; stimulate and provoke public interest and engagement, excitement and debate about S&T, and engage the European science community with global partners and perspectives, including business. ESOF is a platform created by EuroScience to provide the European research and innovation community with a multi-disciplinary forum to discuss new discoveries and debate the direction that research is taking in the sciences, humanities and social sciences, and to provide a focus for attracting global researchers and innovators to Europe. ESOF2016 (‘Science As Revolution’), will take place in Manchester and will showcase the very best of UK and European scientific thought and discovery across all fields (including social science and humanities). It will discuss and explore world-class research within the mainstream of scientific culture and debate without compromising on excellence, and by doing this ESOF2016 aims to support the sustainability of the European research and innovation ecosystem by engaging and inspiring the next generation.";999999;999999;H2020-Adhoc-2014-20;/CSA;THE UNIVERSITY OF MANCHESTER;UK;MARKETING MANCHESTER;UK;;1;0;0;1;0;0 218353;809276;sunlight2.0;CLOSED;"H2020-EU.3.3.;H2020-EU.2.1.1.;H2020-EU.2.3.1.";SMEInst-09-2016-2017;H2020;Highly efficient, solar-powered irrigation pump;2018-03-01;2018-06-30;;"Ennos is a Swiss company founded in 2006 as a spin-off of Berne University of Applied Sciences under the lead of Prof Dr. Andrea Vezzini, who has a long track record in solar energy and motor drive systems. We are an interdisciplinary team of experienced engineers and marketing experts, who have dedicated our efforts to develop and demonstrate sunlight2.0, a second generation of highly efficient, portable solar-powered irrigation pumps targeted for smallholders in isolated rural areas. There are more than 570 million farms in the world, most of them being located in distant rural areas. Out of those farms, about 84% are smaller than 2 ha. Nowadays, bigger crop areas have to be put under irrigation to increase productivity due to a growing population that has to be fed. This implies a growing need for energy and water resources. Besides, 16% of the global population did not have access to electricity in 2016, mainly in rural areas where the majority of smallholders are located. Therefore, smallholder farmers need competitive solutions, economically affordable and efficient and that enable them to increase their profits. sunlight2.0 is a portable and user friendly pump which is highly efficient and affordable to smallholders. sunlight2.0 has almost no maintenance costs and allows farmers to save the cost of diesel or electricity producing zero emissions. During Phase 2 project we expect to increase the efficiency of the pump, reduce weight and optimize production costs compared to our previous sunlight1.0 product. Completion of Phase 2 project and will require €1 million investment, that will provide an estimated ROI of 5.7 by 2025.";71429;50000;H2020-SMEINST-1-2016-2017;/SME-1;ENNOS AG;CH;;;;1;0;0;1;0;0 211116;766835;EExres;CLOSED;H2020-EU.3.6.3.1.;H2020-IBA-SC6-Expand-2016;H2020;Estonian Presidency Research Policy Conference ‘European Research Excellence - Impact and Value for the Society’;2017-06-01;2018-03-31;;"The international high-level conference will be organised during the Estonian Presidency of the European Union Council in Tallinn in October 2017. The conference aims to demonstrate the impact and value of excellent research to the society and thereby strengthen political commitment to ambitious public investments in research in Europe. It encourages to take a perspective that goes beyond short-term gain, and to develop a long-term vision for European research and innovation policy. Research and innovation are pillars of the Europe 2020 Strategy to put Europe back on the path to smart, sustainable and inclusive growth. At the same time, we can observe strong pressure on the research budgets across Europe. The conference has three specific objectives: • Contribute to better communication of the impact and value of bottom-up and interdisciplinary excellent research in increasing EU competitiveness and creating a better future for the society. We want to demonstrate to policy-makers, stakeholders and wider public that excellent bottom-up research is the catalyst of societal development that provides practical solutions for society. • Broaden the understanding on research impact that goes beyond short-term economic stimulus, including impact to policy-making, society, culture and systemic impact. In light of the discussion of the next Multiannual Financial Framework (MFF), discuss how the current macroeconomic models could better take into account the longer-term impact and benefits of investments in R&I. • Contribute to the debate on the future of European research policy in the lead-up to the next Framework Programme. The outcome of the EU Presidency conference will be presented in the final declaration Tallinn Call to Action. Tallinn Call to Action is emphasising the importance of excellent research for the future of Europe; it is about changing research and changing Europe.";207781,25;179656;H2020-IBA-SC6-Expand-2016;/CSA;SIHTASUTUS EESTI TEADUSAGENTUUR;EE;;;;1;0;0;1;0;0 209307;749732;KdpFABC;TERMINATED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Structure-function relationship of chimeric KdpFABC complex;2017-08-01;2019-07-31;;The structure-function relationships that explain the transport mechanism of membrane proteins on a molecular level are poorly understood and define one of the most complex and interdisciplinary research fields at the interface of Biology, Chemistry and Physics. Here I propose the investigation of the KdpFABC complex for the potassium uptake into the cell. It combines features of three membrane transport systems (P-type ATPases, channels and ABC transporters), which traditionally are considered to be mechanistically and structurally distinct. I propose to decipher the mechanism of action of the KdpFABC system, which is likely to overthrow the conceptual boundaries conventionally used to describe membrane transport mechanisms. The work might lead to the design of novel antibiotics, as these systems are exclusively found in prokaryotes. The structural studies will be conducted exploiting the recent breakthroughs in high-resolution single particle cryo electron microscopy (cryo-EM) that will be established by me as experienced researcher and thereby contribute to the cutting-edge research at UG. The complementary expertise of myself in structural biology and of Prof. Slotboom, as a world-leading scientist in the functional characterization of membrane proteins, are ideally suitable for the successful completion of the research objectives. Ultimately, this project will provide me a unique opportunity to establish myself as an independent researcher and use the knowledge and skills acquired to obtain an academic position within the EU.;177598,8;177598,8;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;RIJKSUNIVERSITEIT GRONINGEN;NL;;;;1;0;0;1;0;0 210123;116072;NGN-PET;SIGNED;H2020-EU.3.1.;IMI2-2015-07-03;H2020;Modelling Neuron-Glia Networks into a drug discovery platform for Pain Efficacious Treatments;2017-04-01;2020-03-31;;Chronic Neuropathic Pain is frequently associated with peripheral nerve injury or disease. Peripheral injury activates both neuronal and glial components of the peripheral and central cellular circuitry. While it is widely known that the subsequently altered interactions between neurons and glial cells contribute to pain development and to its chronification, the underlying mechanisms are poorly understood. Developing mechanism-based therapies targeting neuron-glial interactions to treat chronic pain will be crucial for improving the quality of life of many patients. Hence the development of novel therapeutic solutions represents a major challenge that demands a multi-disciplinary approach to decipher and understand pathological mechanisms and to translate them into predictive tools for drug development. The NGN-PET consortium addresses this challenge by forming a highly interdisciplinary team that builds upon expertise in areas of academic research on pain mechanisms, industrial knowhow on human stem cell-based tool development, HTS technologies and drug discovery. To achieve its goal we will develop preclinical model systems and assays which recapitulate the human in vivo situation and which can be interrogated for the identification, validation of molecular targets and the development new treatments. A focus of the project will be chemotherapy induced NP and the interplay between nociceptors, microglia and Schwann cells. NGN-PET will carefully characterize rodent in vivo and in vitro models to identify these mechanisms, and will develop rat and human iPSCs based in vitro systems of neuron-glial co-cultures that can be interrogated for targets and used for compound identification and validation. NGN-PET will thus pose the basis for the translation of these model systems into high throughput screening platforms for pharmaceutical research and drug discovery.;3328000;1500000;H2020-JTI-IMI2-2015-07-two-stage;/IMI2-RIA;AXXAM SPA;IT;"NATURWISSENSCHAFTLICHES UND MEDIZINISCHES INSTITUT AN DER UNIVERSITAET TUEBINGEN;LIFE AND BRAIN GMBH;GRUENENTHAL GMBH;Laboratorios del Dr Esteve, SA;KING'S COLLEGE LONDON";"DE;ES;UK";;1;0;0;1;0;0 210305;746622;FUSION;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;The effects of financial capital accumulation on employment and wealth distribution;2017-07-03;2018-07-02;;"This project will analyse the relationship between the logic of financial accumulation and declining working conditions as well as the widening breach in social inequality affecting large segments of the European population. Studies carried out to date have failed to provide a systematic explanation for the relationship between financialisation, employment and wealth distribution. This project will contribute to filling this knowledge gap in the comparative cases of Spain and the UK, two different poles in terms of Eurozone economies. In the case of Spain, the ER’s (Dr Matilde Massó) current research on financialisation shows a widespread trend whereby financial capital gains of non-financial corporations increase not only when net incomes do, but also when the latter fall within a context of a major economic crisis and high unemployment rates. The PI (Dr Mark Davis) has worked for the Council of Europe, contributing expertise to the Charter of Shared Social Responsibilities. His recent research on democratic finance shows the importance of money as a public resource that allows for equivalences to be drawn between goods and services of varying types, and the distribution of wealth in contemporary capitalist societies. This project, hosted by one of the foremost centres of Economic Sociology in Europe (The Bauman Institute of the University of Leeds), brings together both approaches in order to conduct innovative research into the analysis of the effects that financial accumulation has on the field of employment. The project will boost the ER’s academic career progression as she aims to become a leading world expert in Economic Sociology. The innovative approach of this project lies in the interdisciplinary viewpoint adopted in the analysis of the causes of unemployment and inequality. The exploration of new money-currency systems allowing for more balanced wealth distribution may have the potential for significant long-term socioeconomic impact.";97727,4;97727,4;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;UNIVERSITY OF LEEDS;UK;;;;1;0;0;1;0;0 203545;713279;CAROLINE;SIGNED;H2020-EU.1.3.4.;MSCA-COFUND-2015-FP;H2020;Collaborative Research Fellowships for a Responsive and Innovative Europe;2016-06-02;2021-06-01;;"The CAROLINE Fellowship Programme proposed by the Irish Research Council (IRC) will provide a unique opportunity for researchers to further develop their skills, competencies and experience through inter-sectoral collaboration with NGOs and International Organisations (IO). Proposals will be invited from all disciplines that speak to the overarching theme of global sustainable development as set out under the United Nations 2030 Agenda for shared economic prosperity, social development, and environmental protection. CAROLINE will fund 50 experienced researchers across two modes; International Fellowships (three-year) and Irish Fellowships (two-year). The IRC, a national agency, funds excellent research across all disciplines. Unique aspects of CAROLINE include the European and global resonance of the overarching research theme, the inclusion of NGO and IO partners with the host research performing organisations, flexibility in secondments, comprehensive approaches to equal opportunities and gender aspects, and dedicated core training and career support activities. Research outcomes and activities of the CAROLINE Fellows will benefit Europe, given the significance of the theme to Europe 2020, e.g. in employment, climate change and energy, education, and poverty reduction. CAROLINE will deliver experienced researchers with enhanced skills in inter-sectoral and interdisciplinary research and better access to a wider set of future career opportunities. The IRC has built an impressive array of support for this proposal from stakeholders in Ireland, Europe and internationally, including research performing-organisations, NGOs, IOs and other partners.";9204000;4602000;H2020-MSCA-COFUND-2015;/MSCA-COFUND-FP;AN TUDARAS UM ARD OIDEACHAS;IE;;;;1;0;0;1;0;0 204525;704728;FuSEL;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;FUnerals as public Services in long Eighteenth century London;2016-07-01;2018-06-30;;The research aims to understand the organization and functioning of services for the community in early modern London through a concrete case study, namely the ways in which funerals and burials were managed during the long eighteenth century (1670-1852). I selected the case of London in order to complete a long-term comparative study that began with my doctoral research. By extending my research to London, I will be able to compare it with Paris and Naples, which I analysed in my previous research experiences. These three capitals were the most populous cities in Europe during the study period. How did these multifaceted societies solve issues of collective interest before the birth of modern public services? Which elements did modern public services inherit from them? In order to ask to these questions, I will make use of an interdisciplinary methodology taking advantage of expertise acquired at Birkbeck, University of London, under the guidance of an excellent supervisor (Professor Vanessa Harding). Working in a large, many-faceted academic entity such as the University of London will be a considerable milestone in my career. I will acquire a strong comparative methodology that is essential for my long-term research purpose. Furthermore, I will attain important competences in both educational and research policies, as well as a better understanding of administrative issues, in English-speaking countries, which still differ considerably from the countries where I worked until now (Italy and France). Parallel to the program of research and training, I will put in place a series outreach activities that will enable me to engage with a wider public and share the relevance of historical research for an understanding of today’s problems and the development of adequate responses to these by decision-makers and those working in our institutions and society.;195454,8;195454,8;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;BIRKBECK COLLEGE - UNIVERSITY OF LONDON;UK;;;;1;0;0;1;0;0 201693;713714;REP-EAT;SIGNED;H2020-EU.1.3.4.;MSCA-COFUND-2015-DP;H2020;Food quality and food innovative strategies to prevent reproductive and eating disorders;2016-05-01;2021-04-30;;"The main objective of REP-EAT is to build up a new and innovative research and training doctoral programme (DP) in the interdisciplinary domain of food and healthy diet to deepen the impact of food quality on reproductive Health (REP) and eating disorders (EAT). In compliance with the concept of “One Health”, REP-EAT DP will focus on the effect of diet determinants on both humans and animals thus implying a strict integration amongst food and life science research advances. REP-EAT is aimed at training a new generation of creative, entrepreneurial and innovative Early-Stage Researchers (ESRs). The DP will rely on the joint efforts of qualified tutors involved in three pre-existing doctoral courses in Biotechnology, Food Science and Veterinary Medicine of the beneficiary institution, UniTE. REP-EAT is further strengthened by the partnership (9 EU and 2 USA academic and 23 EU non-academic partners) with qualified complementary groups that have fruitfully interacted in previous successful training and research programmes of UniTE. ESRs can undertake an independent and personalized training and research career development plans to be awarded a European double PhD degree from European University partners. ESRs will be exposed to research and entrepreneurial sectors in each phase of the DP (from selection to mentoring, training, research secondment and dissemination activities) to achieve a wide set of technical and transferable skills required to convert knowledge and ideas into products and services for economic and social benefit, to build up their future career perspectives. The regional authority, Abruzzo Region, will provide cofunding support consistently with the regional Smart Specialization Strategy (RIS3) using ESIF funds, in order to foster the development of qualified human resources in Agro-food area, a leading sector of regional economy in needs of continuous innovation in order to compete in the global market.";1883520;941760;H2020-MSCA-COFUND-2015;/MSCA-COFUND-DP;UNIVERSITA DEGLI STUDI DI TERAMO;IT;;;;1;0;0;1;0;0 202426;706244;IRONLAKE;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Establishing stable IRON isotopes of laminated LAKE sediments as novel palaeoclimate proxy;2016-06-01;2018-05-31;;Under the pressure of human-induced climate change, it is essential to better understand the past natural climate variability. A broader global coverage of high-resolution palaeoclimatic proxy (indicator) data is urgently needed to improve climate projections and adaptation strategies to changing climate and environmental stress. Laminated lake sediments provide invaluable palaeoclimatic information with up to seasonal resolution. The IRONLAKE project aims to develop the innovative methodology of stable iron isotope measurements of laminated lake sediments as a novel proxy for past changes in temperature and wind. Only recently, first studies have hinted that variations in stable iron isotopes of marine and lake sediments reflect changing redox conditions in oceans and lakes, possibly linked to variations in past wind and/or temperature. This project aims to test the hypothesis of a redox-climate-relationship mirrored in iron isotopes. The project will be carried out on existing sediment cores from Lago Fagnano (Tierra del Fuego, Argentina) exhibiting characteristic iron-rich laminae that are most suitable for the approach. In a multidisciplinary perspective, a combination of ultrahigh-resolution micro-facies analysis by thin section microscopy and micro-X-ray-fluorescence elemental scanning will be applied to fully understand the general sedimentological and geochemical processes and, specifically, possible seasonal/climatic variations influencing the formation and deposition of iron-bearing minerals in the lake. The gained knowledge will then be linked with mineral-selective iron isotope measurements to infer the sensitivity of stable iron isotopes to capture climatic variations. The interdisciplinary perspective of this project is designed to advance the innovative field of iron isotope geochemistry and to provide a novel wind/temperature proxy to the palaeoclimate and climate modelling communities.;175419,6;175419,6;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;UNIVERSITE DE GENEVE;CH;;;;1;0;0;1;0;0 201622;708672;SustUrbanFoods;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Integrated sustainability assessment of social and technological innovations towards urban food systems;2016-06-01;2018-05-31;;Urban food systems are sprouting around cities of developed countries to improve the sustainability of cities and citizens’ diets. In particular, urban food systems are being developed upon social and technological innovations to become competitive in the urban environment. A limited number of studies have worked on quantifying the sustainability performance of urban food activities. Even more, studies lack of a three-bottom perspective that integrates the environment, economy and society dimensions. SustUrbanFoods aims to develop an interdisciplinary methodological framework to assess the sustainability of urban food systems with the aim of providing with tools and data for supporting policies and decisions on sustainable urban food systems towards local and green economies. The integration of life cycle assessment and ecosystem services accounting methods is the basis of the SustUrbanFoods’ scheme to analyze the impacts and benefits of urban food systems on the three dimensions of sustainability. Case studies in 4 different countries that exemplify diverse social and technological innovations will be assessed. SustUrbanFoods will provide the fellow with an ideal learning-by-doing framework for improving knowledge, scientific and soft skills, particularly through knowledge exchange and training with the host institution and the partner company. Results will be disseminated to both academia and general public.;168277,2;168277,2;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA;IT;;;;1;0;0;1;0;0 201057;702604;Cryoetch;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Computer modelling and experimental validation of plasmas and plasma- surface interactions, for a deep insight in cryogenic etching;2016-06-08;2018-06-07;;"Microchips have caused a revolution in electronics over the last few decades. Following Moore's law, much effort has been put into continuously shrinking electronic feature dimensions. Indeed, typical feature sizes of semi-conductor decreased from 10 µm in 1971 to 14 nm in 2014. With the shrinkage of feature sizes, plasma etching plays a more and more important role due to its anisotropy during surface processing. However, to go beyond 14 nm features, current state-of-the-art plasma processing faces significant challenges, such as plasma induced damage. Recently, one such novel process with limited plasma damage is cryogenic etching of low-k material with SF6/O2/SiF4 and CxFy plasmas. In this project, the fundamental mechanisms of the plasma, and its interaction with the surface, for these gas mixtures, will be studied to improve cryogenic plasma etching. For this purpose, numerical models (a hybrid Monte Carlo - fluid model and molecular dynamics model) will be employed to describe (i) the plasma behavior for SF6/O2/SiF4 and CxFy gas mixtures applied for cryogenic etching, and (ii) the surface interactions of the plasma species with the substrate during etching. Furthermore, cryogenic etch experiments will also be conducted to validate the modeling results during the secondment. Such an interdisciplinary project, including chemistry, physics, mathematics, computer modeling and chemical engineering, will definitely widen the applicant’s expertise in different plasma investigation approaches.";160800;160800;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;UNIVERSITEIT ANTWERPEN;BE;;;;1;0;0;1;0;0 201359;705709;ENART;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-GF;H2020;Engagement Art: Regional Islamic and Global Pragmatist Aesthetics;2016-05-01;2019-04-30;;"ENART is an integrated research and training programme for innovative knowledge transfer and career development. It will be implemented at the Department of Society and Global Studies at Roskilde University, Denmark (Beneficiary, host of the Incoming Phase), the Department of History of Art at the University of Michigan, USA (Partner Organisation hosting the Outgoing Phase), and SALT, research and exhibition centre in Istanbul and Ankara, Turkey (host of the intersectoral Secondment). The interdisciplinary constellation of these organisations and the supervision they provide complements the researcher’s own art-historical formation and endorses her research project in transregional Islamic Art History around which ENART’s comprehensive dissemination and public-engagement activities are built: The research project is entitled “Engagement Art: Regional Islamic and Global Pragmatist Aesthetics”. “Engagement art” is a new concept that this project introduces in order to define a hitherto overlooked approach to art. This approach conceives of art as a practice and medium which is continuous with everyday life. This project asks what ideas informed engagement art and what practical and historical circumstances interfered with its development and actual enactment. To answer these questions the project traces the development of engagement art from its conception in Istanbul in 1909 to its implementation at the Art-Craft Department in Ankara in 1932. Thereby the research centres on the modes of confluence of regional Islamic and global pragmatist aesthetics. Apart from introducing a new concept to Islamic Art History, the project seeks to develop a new method for the study of non-canonical art and strengthen ties between the history of art made in and outside of Europe, as well as between Art History and its subdiscipline Islamic Art History. The aim of the project is to contribute to the development of an art historiography worthy of a diverse and inclusive society.";278227,8;278227,8;H2020-MSCA-IF-2015;/MSCA-IF-GF;ROSKILDE UNIVERSITET;DK;;;;1;0;0;1;0;0 200464;707996;SPIDE;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Speech-sound Processing in Infant Development and Evolution;2016-05-01;2018-04-30;;"'What are the uniquely human mechanisms of language acquisition that enable infants to start discovering the words and structures of their native language by the end of their first year? Language is undoubtedly a specifically human function, but it is crucial to disentangle between human-specific vs. general-processing skills that allow language acquisition. This project aims at exploring the developmental and evolutionary origins of one of the features of speech processing: the ability to assign specific functional roles to the different categories of sounds composing speech. Indeed, there is a Consonant/Vowel functional asymmetry in the world's languages as well as in speech processing, whereby consonants better fit the requirements of lexical processing (e.g. when writing abbreviations we tend to remove vowels and keep consonants to avoid compromising meaning, as in txt msgng), while vowels are better targets for syntax-related processes. It remains unknown where this 'division of labour' comes from: uniquely human predisposition playing a role in early syntax and lexical acquisition, or consequence of the asymmetry present in the input? In this work we will conduct experiments in infants as well as in rats, to test the hypothesis that the C/V asymmetry : (1) is not the by-product of the physical differences between vowels and consonants, (2) plays a significant role in early language acquisition; (3) derives from more general perceptual biases shared with other species. This interdisciplinary project will use both behavioral and neuroimaging measures in infants and rats to investigate the origins of the C/V asymmetry in language acquisition and evolution.'";158121,6;158121,6;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;UNIVERSIDAD POMPEU FABRA;ES;;;;1;0;0;1;0;0 200227;690958;MARSU;SIGNED;H2020-EU.1.3.3.;MSCA-RISE-2015;H2020;MARine atmospheric Science Unravelled: Analytical and mass spectrometric techniques development and application;2016-02-01;2020-01-31;;"MARSU is a collaborative (4 Member States , including one participant from the non-academic sector, and six Third Countries from South America, Africa and Asia) with the goal of gaining new knowledge and reducing the uncertainty about the effect of aerosols deriving from the air-sea exchange on climate and atmospheric composition connected to air pollution. The results from this key interdisciplinary project will have impact on current and future industrial and legislative developments. Aerosols and clouds have been identified as one of the largest uncertainties in our understanding of the atmospheric and the climate system. In this context, the MARSU team will conduct experiments in dedicated set-ups throughout the member organisations; combined with efforts in the field to determine the organic composition of aerosol particles and its evolution in the Marine Boundary Layer (MBL) and to come up with a revised picture of the effect of sea salt aerosols on climate. Major gaps of knowledge exist in relation to the organic matter present in aerosol particles, which originates from the organic microlayer at the surface of the ocean. The characterization of the organic content of the aerosol particles, the evolution of the chemical and physical properties, interaction with air pollution and effects on climate-related topics form the foci of this proposal. The MARSU consortium brings together world-leading expert scientists conducting cutting-edge laboratory, simulation chamber studies, field sampling and analysis, analytical method development, and modelling studies. A comprehensive and integrated approach to the development of researchers in the key areas of atmospheric science and their link to the oceans and climate is essential to support industrial and legislative development. MARSU will benefit from the strong involvement of a full partner from the private sector who will host researchers and develop research in close collaboration in other MARSU’s partners";1269000;1080000;H2020-MSCA-RISE-2015;/MSCA-RISE;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FR;"LEIBNIZ INSTITUT FUER TROPOSPHAERENFORSCHUNG e.V.;UNIVERSITE LYON 1 CLAUDE BERNARD;UNIVERSITE D'ORLEANS;IONICON ANALYTIK GMBH";"DE;FR;AT";;1;0;0;1;0;0 201222;704245;PACE;CLOSED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Paleogenetic extraction and analysis from challenging environments;2016-06-01;2018-05-31;;"The field of ancient human DNA (aDNA) has rapidly undergone changes over the last decade. These changes have been spurred on through the use of high-throughput sequencing (HTS) technologies. These methodological advancements have increased our understanding of the human lineage to depths thought impossible only a short time ago. For example, aDNA research has shown how modern humans are related to our archaic ancestors, indicating significant admixture events throughout our evolutionary history with the Neanderthals and other now-extinct archaic species. However, to achieve these results, the ancient material has been exceptionally well preserved, owing to favorable, i.e. cold, environmental conditions. For many parts of the world, however, the environmental conditions remain a barrier to the extraction and analysis of aDNA. The nature of aDNA research is inherently interdisciplinary, whereby several branches of inquiry, such as archaeology or genetics, attempt to answer similar evolutionary questions from different perspectives. This proposal attempts to use advanced extraction and sampling methods for aDNA from challenging environments in order to broaden the scope of paleogenetics research. Although continental Europe has gained significantly from these advances, for other parts of the world, such as Southeast Asia and the Near East, this has been more difficult due to formidable preservation conditions. The goal of this proposal is to build on promising preliminary results that target a specific bone in the human skull in order to gain a better understanding surrounding the dynamics of aDNA preservation, while at the same time, gain insight into the evolutionary histories of peoples from warm and humid, or warm and arid, locations. Our proposal incorporates state-of-the-art HTS techniques, includes a comprehensive training program with international collaborators, and benefits from a two-way transfer of knowledge between host and researcher.";187866;187866;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN;IE;;;;1;0;0;1;0;0 201343;705592;INTO;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Inorganic therapeutic nanoparticles for osteoporosis;2016-06-01;2018-05-31;;"The aim of the proposed interdisciplinary project is to design, make and test novel nanoparticles that will have direct and rapid impact in osteoporosis. The unique aspect of these injectable nanoparticles is that they will deliver active therapy locally, to where it is needed, and that the cargo is not a conventional drug, but a sustained delivery of a combination of active inorganic cations and rare earth nanoparticles. Certain cations can promote bone growth and inhibit resorption and nanoceria can scavenge free radicals that would otherwise accelerate osteoporosis. Systemic concentrations of active agents will be much smaller that caused by taking oral drugs. Delivery will be sustained because it is controlled by the dissolution rate of biodegradable mesoporous silica nanoparticles, which will improve over biodegradable polymer capsules that often deliver a burst release of their drug cargo. Beyond the project, long-term impact could include slowing metastasis of tumours into bone (e.g. breast cancer to the sternum). The biodegradable mesoporous silica nanoparticles will be synthesised by sol-gel, while the nanoceria will be synthesized by co-precipitation method and microwave treatment and entrapped within the silica network. Key aspects will be: incorporation of active ions and nanoceria within monodispersed silica nanoparticles of controlled size; ensuring the particles remain dispersed in body fluid (control of surface chemistry); testing efficacy in cell co-culture (uptake and cell stimulation) and investigating the effect of the presence of the particles on immune cells. The effect of process variables on composition, particle size, bioactivity, degradation rate, radical scavenger ability and the cellular response will be investigated.";183454,8;183454,8;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE;UK;;;;1;0;0;1;0;0 200148;703813;C-LEAK;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Rivers as leak in the terrestrial C sink;2016-07-01;2018-06-30;;"Lateral displacement of carbon (C) from soils across inland waters towards the ocean has been intensified due to anthropogenic perturbations and has significant influence on the anthropogenic C budget and the terrestrial C sink. However, Earth System Models (ESM) which are used to simulate the terrestrial C sink at global scale still ignore these lateral fluxes. The project presented here aims at assessing the impact of lateral C fluxes on the anthropogenic CO2 budget using a mechanistically-based approach. To this end, JULES, the land surface component of the UK ESM, will be upgraded with an explicit representation of fluvial transports of soil derived C, including decomposition of organic C in transit and net C fluxes to the atmosphere and aquatic sediments. The model will be calibrated, applied and validated at subcontinental scale for the UK, but the technical developments will support future applications across scales, from catchment to the globe. Historical simulations (1850-2010) will be run to attribute climate change, land-use change mediated soil erosion, and river damming to changes in C exports and C burial in aquatic sediments. Future simulation (until 2100) under contrasting climate and land-use scenarios will be run in order to assess the fate of the inland water C cycle. At the University of Exeter, the fellow will gain experience in Earth System Modelling and improve his process understanding of soil erosion, fluvial transport and sedimentation of C. This combination of expertise will put the fellow into a unique position which meets a clearly defined need in ESM development and increases his chance to obtain a permanent position at a leading European research institute. This project promotes the knowledge transfer in Earth System Modelling between the University of Exeter (GB), Institut Pierre-Simon Laplace (F) and the Université Libre de Bruxelles (Be) and the interdisciplinary exchange between climate science, soil science and geomorphology.";183454,8;183454,8;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;THE UNIVERSITY OF EXETER;UK;;;;1;0;0;1;0;0 200234;706616;MicroPEAT;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Microbial communities of Temperate, Artic and Tropical peatlands and their role in the response of carbon storage function to global change;2016-05-01;2018-04-30;;"The present proposal aim at understanding microbial role in peatland sensitivity to climate change at a Global Scale. Peatlands represent one of the most important terrestrial carbon pools, despite they only cover 3% of the earth’s surface they store one third of all terrestrial carbon. This ecosystem has shown to be sensitive to different disturbances in terms of their carbon storage capacity and it is expected a huge CO2 and CH4 release as well as an increase in dissolved organic carbon exportation to freshwater systems, due to climate change. Peatlands cover large extensions in arctic and temperate zones, but they are also present in tropical regions were their ecology and functioning is almost unknown. Due to the valuable peatland role as carbon sink there has been many intents to find out the effect of global change on their functioning, however we are still far to totally comprehend and predict this effect, existing important unsolved questions on the role of microbial decomposer communities (Fungi, Bacteria and Archaea), the structure-function relationship, and so far, none study has assessed the climate change impact at global scale. In order to fill these gaps I propose to survey the microbial communities in Arctic, Temperate and Tropical peatlands and test how differences in origin-legacy can drive peatlands sensitivity to drought events. The proposed methodology is an interdisciplinary approach (combining molecular thechniques, ecosystem measurements and biogeochemistry) with three big components: 1) initial field work study to systematically assess microbial communities from the 3 regions; 2) a microcosm experiment to test the effect of drought (water table reduction) on peatland functioning; 3) a secondment in a drinking water company to put into a management context the results, as these companies are interested in the by-product formation problem thanks to the DOC enhancing in water supplies due to the loss of peatlands storage capacity.";183454,8;183454,8;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;BANGOR UNIVERSITY;UK;;;;1;0;0;1;0;0 200904;700802;MULTI2DSWITCH;CLOSED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;MULTIfunctional optoelectronic devices based on hybrid heterostructures of 2D materials and photochromic SWITCHes;2016-08-21;2018-08-20;;MULTI2DSWITCH will offer an extremely talented and promising young researcher, with a PhD in physics and an extraordinary track record, world-class training through research in the cross-disciplinary and supra-sectorial field of 2D materials (2DMs) based multifunctional electronics. The proposed research lies at the interface between physics, chemistry and electrical engineering, in the interdisciplinary realms of supramolecular sciences, materials- and nano-science. The overall mission is to train the fellow to become an independent scientist and to prepare him for a leading position in academia or industry. MULTI2DSWITCH’s research programme targets a fundamental breakthrough in the field 2DMs by using a combination of bottom-up and top-down methods to design ultraflat, flexible and photoswitchable heterostructures of 2D crystals and molecular self-assembled monolayers (SAMs). In order to do so, a highly-ordered SAM of photochromic molecules (azobenzenes, diarylethenes or spiropyrans) is prepared on the surface of a graphene layer, by means of low-cost solution processing techniques. The graphene/SAM bilayer is subsequently encapsulated with a 2D semiconductor from the family of transition metal dichalcogenides (TMDs) using the flake-transfer techniques commonly employed for van-der-Waals heterostructure assembly. The photo-tunable properties of the newly prepared hybrid heterostructures will be exploited to develop a series of proof-of-concept multifunctional devices, including optically-switchable diodes and field-effect transistors (FETs), and optically-programmable memory cells. Thanks to the high-degree of mechanical flexibility of both the 2D crystals and the molecular SAMs, these devices will be suitable for integration on flexible substrates. Ultimately, MULTI2DSWITCH aims at developing high-performance flexible multifunctional optoelectronic devices with figures of merit greatly surpassing those of the corresponding state-of-the-art organic devices.;173076;173076;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;UNIVERSITE DE STRASBOURG;FR;;;;1;0;0;1;0;0 201069;702707;Finch Evo-Devo;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Developmental Basis of Beak Shape Variation in Darwin’s Finches;2016-05-01;2018-04-30;;"Darwin’s finches display an extremely high beak shape diversity associated with occupation of various ecological niches. They are the classic textbook example of adaptive radiation under natural selection. The supervisor of this proposal – Dr. Arkhat Abzhanov and colleagues previously used a combination of morphometrics, comparative developmental genetic and functional tests to reveal basic principles underlying beak shape morphogenesis. They showed that the enormous beak diversity in Darwin’s finches could be reduced to three “group shapes” (A, B, and C) and revealed molecular mechanisms causing the scaling–based variation within group “A”, but not yet the processes underlying the more complex shear-based saltational transformation that produced variation between groups. The main objective of this project is to identify the developmental programs underlying the leaps of beak shape diversification during Darwin’s finches’ adaptive radiation – the variation between “group shapes”. I will employ an extensive whole-transcriptome sequencing (RNAseq) screen to search for novel transcripts whose gene expression is associated with the group shape-specific beak curvatures. This will be complemented with genome-wide association study (GWAS) to identify upstream regulators of the actual effector molecules that cause the phenotype. I will validate the best candidates by gain- and loss-of-function tests using retroviral vectors on developing chicken and zebrafinch embryos to reveal their roles in beak morphogenesis. This project will provide novel insights on intrinsic mechanisms that facilitate adaptive morphological diversity, will offer an opportunity for interdisciplinary research interactions and will generate resources valuable to the entire biological community.";183454,8;183454,8;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE;UK;;;;1;0;0;1;0;0 197846;639583;ToxicExpertise;SIGNED;H2020-EU.1.1.;ERC-StG-2014;H2020;Toxic Expertise: Environmental Justice and the Global Petrochemical Industry;2015-08-01;2020-07-31;;This research project critically examines ‘toxic expertise’, the contested politics of making scientific claims about the health impacts of toxic pollution. Toxic expertise has a double meaning: scientific expertise about the effects of toxic pollution, and the toxic nature of expertise that is used to justify a lack of corporate social responsibility. The research focuses on the global petrochemical industry as a significant but controversial source of toxic pollution, with unequal regulations and risks across different countries and populations. Debates about the global petrochemical industry reflect conflicting interests between jobs, prosperity, and health. This research contributes to interdisciplinary social scientific research on science and technology, environmental justice movements, and the uneven geography of capitalism. In particular, it develops sociological arguments that scientific ‘expertise’ is inherently political and socially constructed. This mixed method comparative research will be conducted in three stages. The first stage will examine toxic expertise in the leading global petrochemical companies and environmental non-governmental organisations in Western Europe, North America, and China. The second stage will focus on in-depth case studies in the United States and China, two of the top petrochemical producers in the world. The third stage will develop an international public resource of toxic expertise to address practical challenges of capacity and scale inherent within both dominant and citizen-led epidemiology, by developing accessible information and tools for understanding, monitoring, and reporting toxic pollutants and their health impacts. The project offers the first systematic sociological analysis of the global petrochemical industry in relation to environmental justice, responding to calls within critical social science for the democratisation of science which highlight the need for greater accountability and transparency.;1455108;1455108;ERC-2014-STG;/ERC-STG;THE UNIVERSITY OF WARWICK;UK;;;;1;0;0;1;0;0 197991;675715;MIMESIS;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2015-EID;H2020;Mathematics and Materials Science for Steel Production and Manufacturing;2015-10-01;2019-09-30;;"The five partners EFD (Norway), SSAB, Outokumpu, and University of Oulu (Finland), and WIAS (Germany) propose an EID programme on Mathematics and Materials Science for Steel Production and Manufacturing, where eight PhD projects are jointly carried out, providing a unique interdisciplinary and inter-sectorial training opportunity. The research is focussed on three major topics - induction heating, phase transformations in steel alloys, ladle stirring. Two theses concern hardening: one is the hardening of helical and bevel gears by an optimized single or multi-frequency approach and the other is a novel idea about the hardening of the inner surface of pipes. Two of the theses are related to induction heating applications in the production of high-frequency welded pipes and for pre- and post-heating in the thermal cutting of steel plates. Two theses are concerned with phase transformations during steel production and the final two theses are related to secondary metallurgy in the ladle, optimal alloying strategies and an inverse problem related to stirring efficiency. Despite the fact that most theses projects deal with established processes, they are not fully understood nor fully controllable from a quality point of view. Improved and optimized process control requires quantitative mathematical modelling, simulation and optimization of the complex thermal cycles and thermal gradients experienced by the processed material. Such models require an understanding of the behaviour of the materials from a materials science and phase transformations perspective. Tailored industrial on-site trainings, customized courses in physical modelling and testing of steels as well as numerical simulation of induction heating and flow phenomena combined with scientific research in carefully selected topics on the interface of materials science and applied mathematics will provide the early stage researchers with excellent qualifications to pursue a career in academia or industry.";2110506,12;2110506,12;H2020-MSCA-ITN-2015;/MSCA-ITN-EID;FORSCHUNGSVERBUND BERLIN EV;DE;"OULUN YLIOPISTO;EFD INDUCTION AS;SSAB EUROPE OY";"FI;NO";;1;0;0;1;0;0 199113;690882;QuatSalts;SIGNED;H2020-EU.1.3.3.;MSCA-RISE-2015;H2020;New Quaternary Ammonium Salts for use in Drug Manufacture;2016-03-01;2020-02-29;;"The aim of this project is to bring together subject matter experts from the academic and non-academic sectors to develop three new categories of quaternary ammonium salts to be used as catalysts for the cost-efficient and green manufacture of high value active pharmaceutical ingredients. In order to achieve this objective the proposal brings together 3 partners with complementary skills: University of Naples(UNIN): experts in the preparation and purification of cyclic peptides. Experts in solid phase synthesis and immobilisation of peptides on solid support. KelAda Pharmachem: Phase transfer catalysis/organo catalysis/scale-up of chemical processes University of Linz(JKU Linz): experts in design of new ammonium salts and optimisation of enantioselective phase transfer catalyses. We have broken this proposal into the following separate Work Packages: WP1. Preparation of new designer ammonium salts [WP leader: Kelada] WP2. Preparation of cyclic peptide based ammonium salts [WP leader: UNINA] WP3. Evaluation of new ammonium salt catalysts prepared through WP1 [WP JKULinz] WP4. Evaluation of new Ammonium salt catalysts prepared through WP2[WP leader: UNINA] WP5. Application of Ammonium salts to drug production [WP leader: Kelada] WP6. Scale up of key steps or the manufacture of drugs [WP leader: Kelada] WP 7. Management, Communication & Dissemination [WP leader: KelAda] The above WP’s will be undertaken via a series of interlinked secondment of researchers between consortium partners and will be complemented by a series of training and other initiatives to facilitate interdisciplinary and intersectoral knowledge sharing and exchange.";774000;774000;H2020-MSCA-RISE-2015;/MSCA-RISE;UNIVERSITA DEGLI STUDI DI NAPOLI FEDERICO II;IT;"UNIVERSITAT LINZ;KELADA PHARMACHEM LIMITED";"AT;IE";;1;0;0;1;0;0 196792;639478;AuxinER;SIGNED;H2020-EU.1.1.;ERC-StG-2014;H2020;Mechanisms of Auxin-dependent Signaling in the Endoplasmic Reticulum;2015-06-01;2020-05-31;;"The phytohormone auxin has profound importance for plant development. The extracellular AUXIN BINDING PROTEIN1 (ABP1) and the nuclear AUXIN F-BOX PROTEINs (TIR1/AFBs) auxin receptors perceive fast, non-genomic and slow, genomic auxin responses, respectively. Despite the fact that ABP1 mainly localizes to the endoplasmic reticulum (ER), until now it has been proposed to be active only in the extracellular matrix (reviewed in Sauer and Kleine-Vehn, 2011). Just recently, ABP1 function was also linked to genomic responses, modulating TIR1/AFB-dependent processes (Tromas et al., 2013). Intriguingly, the genomic effect of ABP1 appears to be at least partially independent of the endogenous auxin indole 3-acetic acid (IAA) (Paque et al., 2014). In this proposal my main research objective is to unravel the importance of the ER for genomic auxin responses. The PIN-LIKES (PILS) putative carriers for auxinic compounds also localize to the ER and determine the cellular sensitivity to auxin. PILS5 gain-of-function reduces canonical auxin signaling (Barbez et al., 2012) and phenocopies abp1 knock down lines (Barbez et al., 2012, Paque et al., 2014). Accordingly, a PILS-dependent substrate could be a negative regulator of ABP1 function in the ER. Based on our unpublished data, an IAA metabolite could play a role in ABP1-dependent processes in the ER, possibly providing feedback on the canonical nuclear IAA-signaling. I hypothesize that the genomic auxin response may be an integration of auxin- and auxin-metabolite-dependent nuclear and ER localized signaling, respectively. This proposed project aims to characterize a novel auxin-signaling paradigm in plants. We will employ state of the art interdisciplinary (biochemical, biophysical, computational modeling, molecular, and genetic) methods to assess the projected research. The identification of the proposed auxin conjugate-dependent signal could have far reaching plant developmental and biotechnological importance.";1441125;1441125;ERC-2014-STG;/ERC-STG;UNIVERSITAET FUER BODENKULTUR WIEN;AT;;;;1;0;0;1;0;0 196042;661057;CONGO;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Hybrid Political Orders and Violent Exchanges in the Eastern Congo;2016-04-01;2018-03-31;;Based on anthropological fieldwork in the Eastern Congo, this study investigate ‘hybrid political orders’ e.g. state and non-state groups, such as militias, police, military, local criminal gangs and local authorities such as village chiefs or warlords whose operations transcend the boundaries of what we normally know as state and nonstate and how such actors exercise power through alternative ways of governance and authority. To do so, I apply the concept of ‘violent exchange’ (Jensen 2013). This concept is fruitful in explaining how violence opens up a space in which people are forced to engage with armed networks. In this way, it enables an exploration of bottom-up relations and the how authority yields profits through violent interactions. The study has a strong comparative and interdisciplinary approach as it will contribute to critical inquires that questions the western assumption of state power. The study will be part of a wider research project located at the Danish Institute against torture in Copenhagen, Denmark, where a group of senior researchers are carrying out fieldwork and examining violent exchanges in the Global South. In this way, it will contribute to social science and anthropological theory, to develop the concept of ‘violent exchange’ through fieldwork and bring new empirical data. The results of this study will help to find new methods to monitor violence and to improve human rights work in fragile states.;200194,8;200194,8;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;REHABILITERINGS-OG FORSKNINGSCENTRET FOR TORTUROFRE FORENING;DK;;;;1;0;0;1;0;0 195906;660187;ReaDoubt;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Reasonable Doubt: An epistemological and psychological approach;2015-09-01;2018-04-20;;"The purpose of this research is to shed light on the nature and dynamics of doubt and confidence in complex epistemic decision-making, through a study of the notion of reasonable doubt. While doubt is considered a rational virtue, waiting until complete certainty before accepting and acting upon a given hypothesis is unreasonable in many contexts. Given some evidential support for the hypothesis, the threshold beyond which acceptance rather than doubt is the reasonable option seems to depend on the decisional context (particularly the cost of a possible error): jurors in criminal trials should thoroughly consider alternative scenarios before convicting a defendant; doctors or policy-makers, however, may have to take action upon less strongly confirmed hypotheses, depending on the relative costs and benefits of action/inaction. Such a decision-theoretic view of reasonable doubt relies on the assumption that the consequences of an hypothesis are exogenous to the rational evaluation of its evidential support: one first updates one’s degree of belief in view of the evidence, and then assesses whether, given the context, the hypothesis is beyond reasonable doubt (i.e. should be accepted and acted upon). But is it the case that agents’ degrees of confidence in a hypothesis, and their weighing of various pieces of evidence, are impermeable to the decisional context? Is the juror’s actual belief independent from her having to bring a consequential verdict? This research aims to study the epistemological norms of reasonable doubt, taking account of the psychological reality of the agents’ reasoning. The main objective of the fellowship is to develop an original empirical research programme, testing the effects of the consequentiality of epistemic decisions on reasoning. This interdisciplinary project requires the candidate, an expert philosopher, to acquire experimental skills and knowledge in psychology, under the supervision of a specialist in the psychology of reasoning.";183454,8;183454,8;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;BIRKBECK COLLEGE - UNIVERSITY OF LONDON;UK;;;;1;0;0;1;0;0 194556;649082;BAS-SBBT;SIGNED;H2020-EU.1.1.;ERC-CoG-2014;H2020;Bacterial Amyloid Secretion: Structural Biology and Biotechnology.;2015-06-01;2020-05-31;;"Curli are functional amyloid fibers that constitute the major protein component of the extracellular matrix in pellicle biofilms formed by Bacteroidetes and Proteobacteria. Unlike the protein misfolding and aggregation events seen in pathological amyloid diseases such as Alzheimer’s and Parkinson’s disease, curli are the product of a dedicated protein secretion machinery. Curli formation requires a specialised and mechanistically unique transporter in the bacterial outer membrane, as well as two soluble accessory proteins thought to facilitate the safe guidance of the curli subunits across the periplasm and to coordinate their self-assembly at cell surface. In this interdisciplinary research program we will study the structural and molecular biology of E. coli curli biosynthesis and address the fundamental questions concerning the molecular processes that allow the spatially and temporally controlled transport and deposition of these pro-amyloidogenic polypeptides. We will structurally unravel the secretion machinery, trap and analyse critical secretion intermediates and through in vitro reconstitution, assemble a minimal, self-sufficient peptide transport and fiber assembly system. The new insights gained will set the stage for targeted interventions in curli -mediated biofilm formation and this research project will develop a new framework to harness the unique properties found in curli structure and biosynthesis for biotechnological applications as in patterned functionalized nanowires and directed, selective peptide carriers.";1989488,75;1989488,75;ERC-2014-CoG;/ERC-COG;VIB;BE;;;;1;0;0;1;0;0 194954;654339;QUTEMAG;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Quantum-Enhanced Optical Magnetometers;2016-04-01;2018-03-31;;"During the past ten years tools from Quantum Optics such as quantum-non-demolition (QND) measurements and squeezed light have emerged as powerful means to control quantum states of matter, perform ultra-sensitive measurements, and enhance physical systems beyond their classical limits. At the same time optical magnetometers developed within the discipline of Atomic Physics have established themselves as the most sensitive detectors of magnetic fields with current performance reaching the limits of classical techniques. To date, in a proof-of-principle way, QND and squeezed light have been used to improve the performance of these instruments independently but not within the same device. Their simultaneous use in a best-in-class magnetometer remains an open challenge. To achieve this ambitious research goal we propose to combine QND and squeezed light resources to magnetometry at large atomic densities, i.e. in a regime where spin-exchange collisions dominate the spin dynamics. This novel approach will be key in enhancing current technology most suitable to address challenges in the real world. QUTEMAG combines a wealth of expertise in Optical Magnetometry and Quantum Optics. The Experienced Researcher Dr. Ricardo Jiménez Martínez, is an expert in Optical Magnetometry. The Supervisor Professor Morgan Mitchell is a leader in QND methods and quantum light pioneering the techniques that will enable the quantum-enhancement of optical magnetometers in the proposed work. The goal of the training program of the researcher is to develop new research competencies in quantum optics and managing skills of interdisciplinary research in Quantum Optics and Metrology, Atomic Physics and Photonics.The Host Institution, ICFO-The Institute of Photonic Sciences in Spain, provides a world-class research and training environment to achieve the research and training goals of QUTEMAG during the 24-month span of the project.";170121,6;170121,6;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;FUNDACIO INSTITUT DE CIENCIES FOTONIQUES;ES;;;;1;0;0;1;0;0 195238;656264;LAGRANGE;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;LAte Glacial RANGe Expansion;2016-04-01;2018-03-31;;"From around 25 to 20 thousand years ago, most of northern Europe was covered by ice and humans retreated into refuges in the warmer southern territories. The archaeological record of the Western European Late Pleistocene clearly indicates a refuge encompassing the areas of Cantabria, in northern Spain, and Aquitaine, in southern France. Both archaeological and genetics evidence agrees that it was from this “Franco-Cantabrian” refuge that Western Europe was repopulated in several phases starting at around nineteen thousand years ago. As pioneer groups expanded their ranges into previously uninhabited northern territories, Late Glacial hunter-gatherers had a unique opportunity to engineer their evolving ecosystem or niche. According to the Niche Construction paradigm such practices deeply change the selective pressures of that niche on its populations, both human and non-human, thus affecting not only cultural transmission, but also biological/genetical transmission: a triple inheritance model. The LaGRangE project proposes to study the Late Glacial hunter-gatherer range expansions, and the role of Niche Construction in these. This will be achieved by an interdisciplinary approach to the problem applying established Computer Science methods to archaeological data. Firstly Niche Construction triple-inheritance models will be modelled to understand how niche construction affects the dispersal dynamics of a given population. This new understanding will then be used to model the Late Glacial dispersal of humans out of the Franco-Cantabrian refuge, on a biogeographically realistic domain. This approach will help identify routes, preferred habitats and other dispersal choices taken by the expanding groups.";158121,6;158121,6;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;FUNDACIO PRIVADA INSTITUT CATALA DE PALEOECOLOGIA HUMANA I EVOLUCIO SOCIAL;ES;;;;1;0;0;1;0;0 202195;703893;PATH;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-GF;H2020;PAssive Tracking of people and things for physical beHavior analysis;2016-06-01;2019-05-31;;"The main goal of passive tracking of people and things (PATH) is to define a new paradigm for physical behavior inference, where the dynamics of physical entities are tracked with minimal implementation cost, maximal privacy preservation, and intrinsically protected secrecy. PATH relies on the detection, tracking, and behavior analysis of targets without active devices, by integrating such capabilities in infrastructures for the Internet of things (IOT) that are already present in a monitored environment. This enables several applications including visitor counting and flow monitoring. The objectives of PATH are: (i) to develop a framework for system design and analysis, as well as to derive fundamental limits; (ii) to devise advanced techniques for detection and exploitation of networks of opportunity; (iii) to develop inference techniques based on wireless networks properties for intrinsically secure tracking; (iv) to recognize new patterns related to targets dynamics based on signal feature extraction; (v) to establish a proof-of-concept for an industrial-driven use case. PATH will enhance the potential of the experienced researcher (ER) by relying on: (i) the solid experience of the successful Ph.D. completed by the young ER, which included a year as a visiting student in the USA; (ii) a challenging, interdisciplinary, and multi-sectorial work program; (iii) a genuine mobility program with an outgoing phase at a top tier university, supervised by a world-renowned expert in the field, and with an incoming phase at a high ranked and growing research group; (iv) a secondment program at a leading industry in the field, which confirms the industrial interest and that is tailored to the ER, with an evident commitment in terms of supervision and infrastructures; (v) a rich, five-fold training program, not limited to training through research; (vi) an implementation plan agreed with an advisory board for an efficient achievement of the ambitious objectives.";244269;244269;H2020-MSCA-IF-2015;/MSCA-IF-GF;UNIVERSITA DEGLI STUDI DI FERRARA;IT;;;;1;0;0;1;0;0 202190;703625;ACCELERATE;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;ArChaeological and Climatic data from ELEmental ratios using Rapid Analysis of shell carbonaTE;2016-05-01;2018-04-30;;"ACCELERATE will develop a rapid and affordable technique using Laser Induced Breakdown Spectroscopy (LIBS) to retrieve climatic information preserved in the elemental composition of marine mollusc shell carbonates and establish standardised ways of applying this technique to coastal shell-midden deposits around the world. This will combine the disciplines of Laser Spectroscopy, Climatology and Archaeology to advance the reconstruction of climate change, exploitation of coastal resources and human-landscape interactions at an unprecedented scale and resolution. Anthropogenic shell deposits are found in their thousands across the globe over the last 100,000 years. Locked within the shells are climatic records with a high resolution. This crucial information is currently inaccessible due to expensive and laborious techniques, resulting in small, unrepresentative studies and a lack of comparability between them. ACCELERATE will resolve this by developing LIBS, which will allow rapid chemical analyses, increasing the cost efficiency by a factor of 20, resulting in large datasets. The project will place the ER on an excellent career path because a) the developed method will be in high demand, b) the novel and interdisciplinary nature of the project will attract a wide network of collaborators, and c) the relevance to sites from different continents and periods will allow for wide dissemination of results. This will lay the foundation for affordable and comprehensive climate studies world-wide, which is closely related to Horizon 2020 policy priorities to understand and adapt to climate change. ACCELERATE will make use of the outstanding experimental and cutting edge research facilities at the host institution, IESL-FORTH, to develop an efficient method of producing climate data. The ER and FORTH will exploit and integrate their international contacts covering all continents to develop an international network and the foundation for comparative studies on a global scale.";152653,2;152653,2;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS;EL;;;;1;0;0;1;0;0 209517;741769;PL-ERADays;SIGNED;H2020-EU.5.a.;SwafS-20-2016;H2020;Polish ERA Mobility and Career Days;2017-04-03;2018-03-02;;The project foresees organisation of ERA Career and Mobility Days in Poland at the beginning of 2017/2018 academic year in 5 regions (Warsaw, Krakow, Poznan, Gliwice and Lodz). Each of the events will last 3 days and each day will address different themes related to a researchers career and will include varied forms of knowledge transfer (from presentations to workshops and face-to-face discussions), stressing the international, interdisciplinary and intersectoral dimension of the research profession, promoting at the same time, the EURAXESS initiative. The target audience of the events are young researchers, PhD candidates in particular, and students interested in research. An additional national seminar is planned in Warsaw for Polish institutions having the European HR Excellence logo in order to show them how they can create even more attractive working conditions for researchers, learning from invited experienced European experts. In order to ensure the widest possible impact of the PL-ERADays, the project consortium is composed of the EURAXESS Bridgehead Organisation, as Coordinator, 4 EURAXESS regional Centres and a first Polish company specialising in science promotion. Various organisations and experts experienced in supporting researchers in their professional development will be invited to participate in the project activities. On top of the physical events taking place in the 5 cities, a large-scale online communication campaign is planned as a big part of the project which will be coordinated by the above-mentioned company. Thanks to the campaign and direct involvement of the Polish Ministry of Science and Higher Education, the Polish ERA Days will also impact policy makers, underlining the importance of supporting mobility and career development of researchers in the country where further steps need to be taken to increase jobs, funding and career development support in order to stimulate innovation and economic growth.;147578,75;85000;H2020-SwafS-2016-1;/CSA;INSTYTUT PODSTAWOWYCH PROBLEMOW TECHNIKI POLSKIEJ AKADEMII NAUK;PL;"POLITECHNIKA SLASKA;POLITECHNIKA KRAKOWSKA;UNIWERSYTET LODZKI;OSICA NATALIA;FUNDACJA UNIWERSYTETU IM ADAMA MICKIEWICZA W POZNANIU";PL;;1;0;0;1;0;0 208671;749845;APOLLO;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Assessing population health from exposure to tobacco-specific carcinogens in Belgium using an innovative wastewater-based epidemiology approach;2017-04-01;2019-03-31;;"Tobacco smoking is the major cause of many chronic diseases, especially cancer. Knowledge on population exposure to tobacco smoking is essential to characterise the population health. National questionnaire surveys are currently the main source of population tobacco smoking. However, surveys have clear limitations due to its dependence on true self-reported usage and representativeness of the whole population. International comparison of surveyed data is also restricted due to different questionnaire formats among nations. An additional approach allowing more objective, efficient and near real-time assessment is necessary to address this important societal issue. Hence, the project APOLLO aims at developing and validating an innovative approach, wastewater-based epidemiology (WBE), for assessing population exposure to tobacco and its related carcinogens in the community. This involves analysis of raw wastewater from targeted communities for tobacco-specific biomarkers of exposure and cancer risk (the tobacco-specific nitrosamines (TSNAs) and their metabolites). The project comprises three main objectives: (1) development and validation of the WBE methodology; (2) evaluation of TSNA and metabolite levels in wastewater from different Belgian communities; (3) assessment of population health from exposure to tobacco-specific carcinogens in Belgium. The completion of the project will advance our knowledge on factual and near-real-time assessment of population exposure to these carcinogens from community to national and international levels using WBE as a standardised approach. This will be also a valuable tool to evaluate the efficacy of intervention actions against tobacco smoking and its related diseases in the population and specific community e.g. prisons, high schools. This project will promote my career prospect with enhanced interdisciplinary network and research mobility in Europe.";160800;160800;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;UNIVERSITEIT ANTWERPEN;BE;;;;1;0;0;1;0;0 201534;707618;NIR-BIO-FLU;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Bio-conjugatable and Bio-responsive Near Infrared Fluorochromes;2016-03-01;2018-02-28;;"Near-infrared (NIR) fluorescence molecular imaging is a supra-discipline that enables visualisation of cellular function and real-time tracking of molecular processes in living organisms without perturbing them. If exploited to its maximum potential, NIR-fluorescence could have hugely positive impact for early stage diagnosis of diseases such as cancer, neurological and cardiovascular disease, the optimisation of preclinical and clinical tests for new medication and act as a real-time guide during surgery. This proposal seeks support for a MSC Fellowship to develop new biologically responsive off to on switchable NIR fluorochromes i.e. NIR fluorescent probes that respond selectively to cellular uptake and with specificity for cancer cells achieved through bio-conjugation with proven targeting agents. Specifically, the focus is on the design, synthesis, photophysical characterisation, in vitro cell imaging and preliminary in vivo assessment of such probes for the ultimate in vivo detection of colorectal cancer metastasis. Colorectal cancer is the third most common cancer and remains a major public health issue in Europe because of its high prevalence, morbidity, and mortality. The synergetic combination of the host laboratory’s interdisciplinary expertise, the host institution’s ability to deliver a comprehensive training program and the applicant’s excellent prior Ph.D. training experience in developing fluorescence chromophores with function-tailored photophysical properties is the perfect match to deliver the project goals and provide the stepping stone to independent researcher for the applicant.";175866;175866;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;ROYAL COLLEGE OF SURGEONS IN IRELAND;IE;;;;1;0;0;1;0;0 201487;707161;NanoCap;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Sustainable Polypeptide Nanoparticle Platform for Drug Delivery;2016-04-01;2018-03-31;;Biodegradable and biocompatible nanoparticles have high potential as viable carriers of active compounds in a broad range of applications for example for cosmetic ingredients as well as therapeutically active compounds such as vaccines, genes, drugs and other biomolecules (drug delivery). To advance current polymer nanoparticle technology we propose a novel nanomaterial platform based on synthetic polypeptide only comprising amino acid building blocks. The proposed system amalgamates the advantages of natural polymers (polypeptides) with the advantages of synthetic polymer chemistry, i.e. molecular weight and composition control. This will result in an innovative biodegradable nanomaterials platform highly adaptable to different cargoes and applications in the attractive Life Science sector. Feasibility will be investigated by loading and release studies of therapeutics for example small molecule drugs as well as hard-to-deliver next generation biopharmaceuticals. This highly interdisciplinary project between polymer, materials and pharmaceutical science will contribute to the advancement of this field addressing industry informed needs i.e. adaptable, nature-inspired nano-delivery systems at the forefront of fundamental and applied research. The applicants diverse experience in academic and industrially informed projects makes him an ideal match for this project. It provides a unique environment for the researcher to develop his skills supported by unique scientific and complementary training and accelerate his academic career in applied medicinal and biomaterial science. The dissemination of research results will target the professional audience as well the general public through outreach activities.;175866;175866;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;ROYAL COLLEGE OF SURGEONS IN IRELAND;IE;;;;1;0;0;1;0;0 195954;660480;POSEIDON;TERMINATED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;novel bioreactor Platform for reprOducible, Scalable ExpansIonand cardiac DifferentiatiON of hiPSC in suspension culture;2015-10-01;2017-09-30;;Human induced pluripotent stem cells (hiPSCs) have the potential to revolutionize biomedical sciences, however the standardised mass production, indispensable for their industrial and therapeutic use, is still a major challenge. Impeller stirred-tank bioreactors, currently used for hiPSC bioprocessing, impose detrimental stresses on cultured hiPSCs, resulting in heterogeneity of cells and cell-aggregates, limited bioprocess reproducibility, and low hiPSC expansion efficiency at high costs. The ambitious purpose of the POSEIDON project is the development of a next-generation automated bioreactor platform to significantly improve reproducibility, efficiency and cost-effectiveness of scalable hiPSC expansion. To demonstrate the utility of the method for the production of valuable human cell types, a novel process for hiPSC-cardiomyogenic differentiation will also be established. This pioneering bioreactor will be developed by advanced engineering design methods and will enable controlled hiPSC suspension culture by non-impeller-dependent low-shear hydrodynamic conditions. Purposely designed automated systems will lead to bioprocess standardisation with enhanced reproducibility, efficiency and scalability beyond the state in the art. The proposed Fellowship will enable a highly interdisciplinary collaboration between the Researcher, a talented post-doc with a significant track record in bioengineering, and the supervisor, a world leader in stem cell bioprocessing, whose group is embedded in one of Europe’s leading hubs for regenerative biomedicine. These working conditions will effectively promote the Researcher’s professional development, providing her with excellent new expertise in stem cell bioprocessing and fundamental leadership skills, significantly widening her career perspectives. The project outcomes will be of tremendous benefit to the European biomedical and pharmaceutical sectors, contributing to the European excellence, competitiveness and quality of life.;159460,8;159460,8;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;MEDIZINISCHE HOCHSCHULE HANNOVER;DE;;;;1;0;0;1;0;0 195595;658358;SIDEW;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Seabed Imprint of Dense Shelf Water Cascading;2016-04-01;2018-03-31;;"Dense shelf water cascading (DSWC) is an atmosphere-driven seasonal phenomenon that occurs in marine regions off Europe and elsewhere. DSWC starts when surface waters over the continental shelf become denser than surrounding waters and sink, generating a near-bottom turbulent flow that moves downslope along the seabed. This process contributes to the deep ocean ventilation and in the global thermohaline circulation (and hence global climate), and involves the massive transfer of energy and matter from shallow to deep waters. While frequently cited as a possible control of the seafloor morphology, there is a lack of studies isolating the DSWC geomorphic effects from other processes known to shape continental margins. This project aims to study the seafloor imprint of DSWC using high-resolution field data and interdisciplinary concepts. The primary focus will be on multibeam bathymetry data sets from 6 areas affected by DSWC. 8 leading research institutions committed to provide the data required. The main expected results are: 1) a better understanding of the physical processes involved in the propagation of DSWC flows, 2) a quantification of their capacity to erode and deposit sediment, and 3) a characterization of the sensitivity of DSWC formation and distribution to climate change in Polar Regions. The host institution expertise on the links between ice sheet dynamics, climate change and marine geological records will be crucial for the training of the applicant and for the success of the project. The planned secondment will add a numerical modelling component so that an in-depth knowledge of the physical processes involved in the propagation of DSWC is achieved. This pioneering work will extend European leadership in the study of DSWC, address EU challenges in the Horizon 2020 programme, and be of interest to industries exploring for natural resources. The project represents an extraordinary opportunity for the applicant to develop technically and professionally.";195454,8;195454,8;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;UK;;;;1;0;0;1;0;0 195193;655938;ZEPHYROS;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;The dawn of writing in Western Mediterranean: a comparative approach to the Iberian epigraphic corpus;2015-09-15;2017-09-14;;"This project proposes a study of all known Iberian inscriptions (about 2.000 documents dating from the 5th century BC to the 1st century AD) in a comparative and interdisciplinary perspective. The study of the Iberian corpus will be set in a broad cultural context, including the rise of the first Western written traditions and their linguistic and cultural contacts. I will focus on issues such as the relationship between text and object, the Iberian adoption of exogenous epigraphic models (mainly Phoenician/Punic, Greek and Latin), and the level of literacy within the male and female spheres of this society. Although the Iberian language in not yet fully deciphered, its epigraphic texts represent a cornerstone of the ethnological and cultural understanding of the protohistoric peninsular peoples and their insertion within the Mediterranean world. For the time being, however, there is no comprehensive study of the Iberian corpus, which has grown considerably over the past decades. On the other hand, there has been a tendency to study the Iberian world and its written culture in an overly isolated way, without sufficiently considering the panorama of neighbouring territories, which provide significant parallels. The specific objectives of this project can be synthetized as follows: publication of the entire corpus of Iberian inscriptions according to current academic criteria, including a digital open access version; linguistic analysis of these texts with a special attention to the cultural context in which they were produced; study of the Iberian written culture in a broad cultural context, including neighbouring territories such as Northern Africa. This project will therefore contribute to the understanding of the Iberian language as well as the circulation of cultural models within the Western Mediterranean. It will ultimately represent an innovative step toward the comprehension of the birth of European identities.";173076;173076;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;UNIVERSITE DE PARIS-SORBONNE (PARIS IV);FR;;;;1;0;0;1;0;0 217975;804247;QNets;SIGNED;H2020-EU.1.1.;ERC-2018-STG;H2020;Open Quantum Neural Networks: from Fundamental Concepts to Implementations with Atoms and Photons;2019-06-01;2024-05-31;;Reaching a fundamental understanding of quantum many-body systems and fully harnessing their computational power for information processing is one of today’s greatest scientific challenges. To date, unprecedented research efforts are underway to build quantum devices, which would outperform the most powerful classical computers. At the same time, neural networks are currently revolutionising the handling of large amounts of data, with enormous success in pattern and speech recognition, machine learning, the analysis of ‘big data’ and ‘deep learning’. Driven by the hope of combining massive parallel information processing in neural networks with quantum advantages like computational speedup, there have been various efforts to develop quantum neural networks – without satisfactory answers to date. The overarching goal of this theoretical research programme is to tackle this enormous challenge from a fresh perspective: we will establish and explore a conceptual framework for quantum neural networks and identify quantum optical physical building blocks, based on concepts in the domain of open many-body quantum systems. This ambitious aim will be achieved by interlinking a multitude of scientific areas ranging from atomic physics, quantum optics, quantum engineering and condensed matter physics to quantum information and computer science. This research will not only generate a genuine step change in our fundamental understanding of the ways nature allows for quantum information processing. It will also lay the foundation for quantum neuromorphic engineering of a new generation of quantum neural hardware in state-of-the-art and newly emerging experimental systems of ultra-cold atoms and trapped ions. With my interdisciplinary background in quantum information and quantum engineering, quantum optics and atomic physics, I am in a unique position to successfully realise this research. I will also strongly benefit from the vital scientific environment at Swansea University.;1486439;1486439;ERC-2018-STG;/ERC-STG;SWANSEA UNIVERSITY;UK;;;;1;0;0;1;0;0 218257;805046;EvoConBiO;SIGNED;H2020-EU.1.1.;ERC-2018-STG;H2020;Uncovering and engineering the principles governing evolution and cellular control of bioenergetic organelles;2019-07-01;2024-06-30;;"'Complex life on Earth is powered by bioenergetic organelles -- mitochondria and chloroplasts. Originally independent organisms, these organelles have retained their own genomes (mtDNA and cpDNA), which have been dramatically reduced through evolutionary history. Organelle genomes form dynamic populations within present-day eukaryotic cells, akin to individuals co-evolving in a 'cellular ecosystem'. The structure of these populations is central to eukaryotic life. However, the processes shaping the content of these genomes through history, and maintaining their integrity in modern organisms, are poorly understood. This challenges our understanding of eukaryotic evolution and our ability to design rational strategies to engineer bioenergetic performance. EvoConBiO will address these questions using a unique and unprecedented interdisciplinary approach, combining experimental characterisation and manipulation of organelle genomes with mathematical modelling and cutting-edge statistics. This highly novel combination of experiment and theory will drive the field in a new direction, for the first time uncovering the universal principles underlying the evolution and cellular control of mitochondria and chloroplasts. Our groundbreaking recent work on mtDNA suggests a common tension underlying organelle evolution, between genetic robustness (transferring genes to the nucleus) and the control and maintenance of organelles (retaining genes in organelles). EvoConBiO will reveal the pathways underlying organelle evolution, why organisms adapt to different points on these pathways, and how they resolve this underlying tension. In addition to these 'blue sky' scientific insights into a process of central evolutionary importance, we will harness our findings to 'learn from evolution' in high-risk high-reward development of new experimental strategies to engineer chloroplast performance in plants and algae of importance in EU agriculture, biofuel production, and bioengineering.'";1417862;1417862;ERC-2018-STG;/ERC-STG;UNIVERSITETET I BERGEN;NO;THE UNIVERSITY OF BIRMINGHAM;UK;;1;0;0;1;0;0 200495;701319;PARPin;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Regulation of (ADP-ribosyl)ation signalling in the DNA damage response: elucidating the function of a novel PARP1/ARTD1 interactor;2016-03-01;2018-02-28;;"(ADP-ribosyl)ation is a dynamic post-translational modification synthesised by PARPs/ARTDs and regulates a diverse array of cellular processes, including the DNA damage response (DDR). The last decade has significantly improved our understanding of the key enzymes involved in (ADP-ribosyl)ation and the cellular pathways they function within. However, our understanding of how these enzymes are regulated is lacking and demands further investigation. In this proposal I seek to redress this. I have provided promising preliminary data identifying a novel uncharacterised interactor of PARP1 involved in the DDR. I expect that this novel protein will have a fundamental role in PARP1 biology in cells given that the two have co-evolved and form a protein complex in cells. I will implement newly available cutting-edge technologies, such as CRISPR-Cas9 and quantitative cell biology approaches, into an interdisciplinary strategy involving genetics, cell biology, structural biology and biochemistry. This strategy will allow me to address the following research objectives: (1) elucidate the function of this protein complex in genome maintenance (2) determine the atomic structure of the complex (3) define the physiological function of the protein complex using genetic mouse models. This timely and holistic approach will allow me to answer crucial outstanding questions related to the regulation of (ADP-ribosyl)ation signalling for the first time. Consequently, this will be the first mechanistic study of its function and therefore my research objectives are likely to yield original insights into novel aspects of (ADP-ribosyl)ation signalling. The objectives described in this proposal will enhance my potential to become an independent investigator by promoting the diversification of my technical competences through training at a world-leading institute and host laboratory. Therefore, the proposal is well aligned with the over-arching aims of the Work Programme.";183454,8;183454,8;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;UK;;;;1;0;0;1;0;0 200610;708935;SMAC;CLOSED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Smart Markets via Computation;2016-10-01;2017-12-31;;"E-commerce, modern-day government auctions, the sharing economy – these all have in common the optimization of resource allocation through the combination of economics and computation. This trend holds enormous socio-economic opportunity: for example, it allows online auctions, personalized advertising that supports the internet ecosystem, government repacking of radio spectrum to support growing communication needs, and flexible pricing that reflects true demand. It also poses an enormous challenge due to the sophisticated treatment of resources it requires, a challenge which theoretical computer science and algorithmic game theory in particular are uniquely positioned to address. Economists have known for decades that when resource allocation involves complex constraints or preferences, there will be market failures and failed auctions. At the heart of these failures is the presence of complements, which occur when economically-efficient allocation of one resource depends on that of another; in mathematical language this can be described as lack of convexity. Remarkably, this economic phenomenon is closely linked to hardness of computation, which has been extensively studied in theoretical computer science for the past 50 years. The goal of this interdisciplinary research program is to apply the theoretical understanding of non-convexity achieved in computer science, coupled with the flexibility provided by computational markets, in order to design smarter economic mechanisms. As increasingly more resource allocation in our society takes place by interaction with computational mechanisms, a unified computational and economic approach is necessary to prevent market failures and enable the full realization of the potential to boost social welfare.";91254,6;91254,6;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;THE HEBREW UNIVERSITY OF JERUSALEM;IL;;;;1;0;0;1;0;0 195798;659468;Transnational Localism;CLOSED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Transnational Localism and Music after the two World Wars: the case of Francis Poulenc;2015-09-01;2017-08-31;;"This project looks at the role composers played in the construction of European culture in the aftermath of two World Wars. Taking Francis Poulenc as an example of a French composer who experienced war twice, it looks at his creative responses to the wars. It prioritises the musical and cultural significance of localised urban, suburban and rural places in shaping a distinctive musical and national identity, an identity that was recognised by his contemporaries as representing a generation; it also scrutinises his international activities in pursuit of cultural and artistic co-operation, collaboration and exchange. The project includes a study of Poulenc’s UK connections, using understudied archival materials to explore his collaborations with composers such as Britten and Lennox Berkeley, his presence in concert life and his clandestine WWII activities with the BBC. It also examines the significance of the European-American artistic exchanges from the post-WWI period as a form of cultural co-operation and propaganda. Transnational Localism shows the extent to which creative artists reflected the trauma of conflict, contributed to peace-building and to national and European identity on a cultural level and participated in politics without needing to be explicitly politically engaged. Musicology was identified as an area of strategic priority by the European Science Foundation, Standing Committee for the Humanities in 2008. This project responds to this challenge by exploring the role of music in shaping identities on individual, generational, national and European levels. It also takes the inherent interdisciplinary nature of musicology a stage further by designing a training programme and research project that is multidisciplinary with the aim of establishing research cooperation that is of mutual benefit to European and Anglophone scholarly traditions in the Humanities and Social Sciences.";183454,8;183454,8;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;ROYAL NORTHERN COLLEGE OF MUSIC;UK;UNIVERSITY OF KEELE;UK;;1;0;0;1;0;0 195790;659437;HistoricEpi;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Quantiative Study of Major Historic Epidemics and Transitions to longer, healthier lives;2015-10-01;2017-09-30;;"Only 150 years ago, one in five Europeans died in infancy, life expectancy was 40 years, and the leading causes of death were infectious diseases: tuberculosis, smallpox, measles, pertussis, diphtheria, cholera, typhoid fever, scarlet fever. But in just a few decades beginning about 1880, life expectancy rose dramatically as infectious disease mortality plummeted. This “2nd epidemiologic transition”, in which chronic diseases began replacing infections as leading causes of death, occurred well in advance of antibiotics and most vaccines. Many factors have been proposed to explain it, including improved nutrition, sanitation, clean drinking water, better housing and the emergence of social support systems. Little has been done, however, to systematically rescue and quantitatively study historic health data and rigorously investigate the epidemiologic transition. I lay out here an ambitious, novel, interdisciplinary and feasible proposal to do just that. In the process, I will broaden my research scope from statistical modeling of historic pandemic influenza to all historic infections, understand the historical context in which the transition occurred, and master new concepts in dynamic disease modeling. Danish historic medical data are uniquely detailed and reach far back in time, and are uniquely suited for quantitative studies of long time series of morbidity and mortality, with the promise to further illuminate the epidemiology of important diseases including smallpox, cholera, and measles. After 25 years abroad as a senior researcher at the National Institutes of Health and Professor of Global Health in the U.S., I now wish to return to my native Denmark. I had the honor this year to be elected to the Royal Danish Academy of Sciences and Letters, and receive funding to be a visiting professor at the University of Copenhagen, and trust this signals the beginning of my successful re-integration to European academia.";212194,8;212194,8;H2020-MSCA-IF-2014;/MSCA-IF-EF-RI;KOBENHAVNS UNIVERSITET;DK;;;;1;0;0;1;0;0 209474;715125;METRO;SIGNED;H2020-EU.1.1.;ERC-2016-STG;H2020;International Organisations and the Rise of a Global Metrological Field;2017-04-01;2022-04-30;;"The production of global metrics by International Organisations has not only penetrated the transnational social and policy fields; it has also become an integral mode of the ways International Organisations interconnect. Through their collaborative practices of quantification and commensuration, International Organisations are both constituting new realities and being reconstituted themselves. Thus, the dominance of global measurement regimes has profound implications for the ways International Organisations interact, and for the environments these new interrelationships come to generate. How is one to make sense of this emerging reality? The embryonic –but rapidly deepening– alliances between International Organisations to find global solutions to global crises, is an opportune moment for a two-fold enquiry: a. an in-depth investigation of the labour of the joint production of metrics; and b. an examination of the ways this labour reconfigures interdependencies between International Organisations and hence the field of transnational governance itself. This is a novel, problem-driven perspective that goes beyond the role and impact of International Organisations through ‘governing by numbers’: instead, we bring together multiple bodies of knowledge in order to cast light on the role metrics play in re-shaping the data collectors themselves. Hence, focusing on the policy areas of Education and Development, this is an interdisciplinary study of the ways International Organisations co-exist, compete and survive in an increasingly quantified yet uncertain world. Building on International Relations theory, Science and Technology Studies, and using theoretical perspectives from Organisational Sociology, as well as the newly emerging field of the social studies of metrics, this research will apply a mixed-methods research design to examine the interrelationships of International Organisations in co-constructing the global metrological field.";1199805;1199805;ERC-2016-STG;/ERC-STG;THE UNIVERSITY OF EDINBURGH;UK;;;;1;0;0;1;0;0 202598;682237;EvoStruc;SIGNED;H2020-EU.1.1.;ERC-CoG-2015;H2020;The physics of antibiotic resistance evolution in spatially-structured multicellular assemblies;2016-06-01;2022-05-31;;"The rise in bacterial infections that are resistant to antibiotic treatment poses a major global health challenge. Addressing this challenge is not just a clinical issue: understanding bacterial resistance evolution calls for an interdisciplinary approach, in which the development of new physics, in coordination with biology, chemistry and engineering, has a central role to play. In particular, statistical physics, to predict the stochastic emergence of drug-resistant mutants, must be integrated with soft matter and chemical physics, to understand the spatial organization of the bacterial populations within which this happens. Bacterial infections are very often spatially heterogeneous. This is known to influence the outcome of antibiotic treatment – for example bacterial biofilms, which form on the surfaces of medical implants, are notoriously hard to remove. However, much less attention has been paid to the role of spatial structure in the evolution of drug resistance, i.e. the emergence and spread of genetically drug-resistant bacterial strains. I will lead a research programme which will for the first time uncover the two-way link between the emergence of spatial structure in bacterial multicellular assemblies and the evolution of drug resistance. The programme builds on my current theoretical, simulation and experimental work. I will first determine the basic principles of evolution in drug gradients using theoretical models, combined with experiments in a controlled, 1D geometry. I will then explore how these principles translate to the more realistic scenario of bacterial biofilms, where spatial structure and drug gradients are emergent properties, using advanced computer simulation methods and both confocal microscopy and evolution experiments. In the final part of the programme, I will use these insights to reveal optimization principles for the design of evolution-resistant surface coatings for applications in medical devices.";1826984;1826984;ERC-2015-CoG;/ERC-COG;THE UNIVERSITY OF EDINBURGH;UK;;;;1;0;0;1;0;0 197860;647586;SESE;SIGNED;H2020-EU.1.1.;ERC-CoG-2014;H2020;Social Evolution and Social Engineering of bacterial Infections;2015-08-01;2021-07-31;;"Micro-organisms were believed until recently to live independent, unicellular lives but are now understood to rely on complex systems of social behaviours for survival. In pathogenic bacteria, cooperation and communication between cells leads to increased virulence and the understanding of how these behaviours evolve is of fundamental importance to the future of human health. Almost nothing is known, however, about social behaviours of bacteria infecting human hosts, and research on social behaviour in microbes is limited to well-characterised lab strains. This proposal describes a program of research designed to exploit the opportunities offered by an interdisciplinary approach to address the growing challenge posed to human health by disease caused by bacterial infection. Specifically, I have three primary objectives: (1) to develop a model system for investigating social behaviour in long-term bacterial infections; (2) to identify evolutionary mechanisms driving dynamics of social behaviour in long-term infections and (3) to exploit social dynamics in the treatment of bacterial infection. This proposal applies evolutionary theory to the clinical challenge of bacterial infection to develop novel intervention strategies beyond the scope of conventional medicine, which is based primarily on understanding of bacteria at the cellular level.";1954633;1954633;ERC-2014-CoG;/ERC-COG;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;UK;;;;1;0;0;1;0;0 220890;819046;makingtheretina;SIGNED;H2020-EU.1.1.;ERC-2018-COG;H2020;Principles of retinal neuronal lamination from zebrafish to humans;2019-10-01;2024-09-30;;"Neuronal lamination is a hallmark of many diverse brain areas where it is important for efficient circuit formation and neuronal wiring. Despite this significance, the cellular and tissue scale principles that ensure successful and robust lamination are not fully understood. In particular, how cell-tissue interactions and biomechanics influence neuronal lamination is only scarcely explored. To fill this gap, we will use the vertebrate retina with its five neuronal cell types arranged in a highly ordered pattern to investigate the emergence of neuronal lamination. We will initially use the zebrafish system and employ long term light sheet imaging to reveal the migration behaviour of the different retinal neurons. Based on this, transcriptomics approaches will enable the dissection of cellular pathways and extracellular cues involved in neuronal migration and overall lamination. To dissect how biomechanics influence lamination, we will use Brillouin microscopy to explore the influence of changing tissue stiffness on lamination and test the role of differential adhesion. These combined results will be the basis to expand studies to the human system and ex vivo human organoids to generate insights into human retinal development. To date, systematic studies investigating molecular pathways in combination with biophysical parameters to understand brain formation across model systems are rare. Due to our previous expertise, we are in an excellent position to perform such interdisciplinary, integrative and interspecies approach. This will unveil common denominators of retinal neuronal lamination in zebrafish, humans and human organoids and thereby reveal the similarities of retinal development in different species and how developmental programs compare in vivo versus ex vivo. In addition, while this proposal focuses on neural lamination in the retina, findings will also inspire future cross-disciplinary studies investigating neuronal lamination in other parts of the brain.";1923750;1923750;ERC-2018-COG;/ERC-COG;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;DE;;;;1;0;0;1;0;0 220794;788616;YMPACT;SIGNED;H2020-EU.1.1.;ERC-2017-ADG;H2020;The Yamnaya Impact on Prehistoric Europe;2019-01-01;2023-12-31;;Dramatic migrations in the third millennium BC re-shaped Europe, modifying its economy, society, ethnicity and ideological structure for ever. The best incentive proxy are populations that moved from the steppes of Russia, spreading as far west as Hungary, implanting a pastoral economy with widespread innovations. These dynamic people covered thousands of kilometres within a few centuries, and organised direct physical relations over the steppes for the first time. This synchronism is promoted by a society organised to fit to this lifestyle, with new herding techniques, likely use of wagons and domesticated horses, and a protein-rich diet, whose adaptive advantages are evident from the physical record in human skeletons and territorial extensions. This is the Yamnaya complex, whose impact remains visible today in the European gene pool and apparently the propagation of Indo-European languages. This international and interdisciplinary project examines the data from 320 excavated burial mounds and c.1350 burials to calibrate these changes, also against a control sample of supposedly local and neighbouring populations. The archaeological, biological and environmental information allows large, new datasets to be built, whose systematic interrogation and modelling should reveal the formative processes behind these changes. Assessing funeral archaeology, material culture, and exchange pattern defines their culture and impact. Scientific analyses of skeletons expose relations of origin, degrees of consanguinity, diet, and histories of individual mobility over single lifetimes with new precision and replicability. They should also act as proxy datasets for environmental changes using further analytical techniques in a context of landscape evolution. Diachronic patterns within these sets should link with aspects of the internal social dynamics, such as the creation of new status positions, visible later in the Pan-European Corded Ware and Bell Beaker groups.;2494209;2494209;ERC-2017-ADG;/ERC-ADG;HELSINGIN YLIOPISTO;FI;"JOHANNES GUTENBERG-UNIVERSITAT MAINZ;SZENT ISTVAN UNIVERSITY;UNIVERSITY OF BRISTOL;UNIVERSITY COLLEGE LONDON";"DE;HU;UK";;1;0;0;1;0;0 221214;826121;iPC;SIGNED;H2020-EU.3.1.5.3.;SC1-DTH-07-2018;H2020;individualizedPaediatricCure: Cloud-based virtual-patient models for precision paediatric oncology;2019-01-01;2022-12-31;;Effective personalized medicine for paediatric cancers must address a multitude of challenges, including domain-specific challenges. To overcome these challenges, we propose a comprehensive computational effort to combine knowledge-base, machine-learning, and mechanistic models to predict optimal standard and experimental therapies for each child. Our approach is based on virtual patient models–in-silico avatars whose analysis can inform personalized diagnostics and recommend treatments. Our platform will also allow care givers to query models and infer benefits and drawbacks for specific treatment combinations for each child. To construct these models, we will combine state-of-the-art computational methods and data from molecular assays, and clinical and preclinical studies. We will test their predictions prospectively on data from clinical trials and test therapies in pre-clinical settings. We will focus on a select panel of paediatric tumours including both high-incidence and high-risk tumour types. To accomplish our goals, we have assembled an interdisciplinary team consisting of basic, translational, and clinical researchers—all amongst the leaders in their respective fields—and established strong relationships with European Centres of Excellence, patient organizations, and clinical trials focus on personalized medicine for our proposed case studies. We will produce, assemble, standardize, and harmonize accessible high-quality multi-disciplinary data and leverage the potential of Big Data and HPC for the personalized treatments of European citizens. We will make our models and data available through a cloud-based platform, whose exploitation will be maximised through a collaboration with the European Open Science Cloud initiative. In summary, iPC will address the critical need for personalized medicine for children with cancer, contribute to the digitalization of clinical workflows, and enable the Digital Single Market of the EU data infrastructure.;15066525;14748400;H2020-SC1-DTH-2018-1;/RIA;TECHNIKON FORSCHUNGS- UND PLANUNGSGESELLSCHAFT MBH;AT;"LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN;UNIVERSITEIT GENT;XLAB RAZVOJ PROGRAMSKE OPREME IN SVETOVANJE DOO;IBM RESEARCH GMBH;BAYLOR COLLEGE OF MEDICINE;UNIVERSITA DEGLI STUDI DI NAPOLI FEDERICO II;DEUTSCHES KREBSFORSCHUNGSZENTRUM HEIDELBERG;ALACRIS THERANOSTICS GMBH;INSTITUT DE INVESTIGACIO EN CIENCIES DE LA SALUT GERMANS TRIAS I PUJOL;CONSIGLIO NAZIONALE DELLE RICERCHE;INSTITUT CURIE;PRINSES MAXIMA CENTRUM VOOR KINDERONCOLOGIE BV;UNIVERSITAETSKLINIKUM HEIDELBERG;UNIVERSITAT ZURICH;THE CHILDREN'S HOSPITAL OF PHILADELPHIA NON PROFIT ORG;TECHNISCHE UNIVERSITAT DARMSTADT;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;CHILDREN'S MEDICAL RESEARCH INSTITUTE;Academisch Medisch Centrum bij de Universiteit van Amsterdam;BARCELONA SUPERCOMPUTING CENTER - CENTRO NACIONAL DE SUPERCOMPUTACION";"DE;BE;SI;CH;US;IT;ES;FR;NL;AU";;1;0;0;1;0;0 220886;818941;LINCHPIN;SIGNED;H2020-EU.1.1.;ERC-2018-COG;H2020;A platform to LINk between CHemistry and PhysIcs of colloidal Nanomaterials;2020-01-01;2024-12-31;;"The recent successful applications of photon-in-photon-out spectroscopy in condense matter physics, bio-inorganic chemistry and catalysis build upon the high brilliance of modern X-ray sources and realization of dedicated emission spectrometers. However, probing with highly energetic X-ray beam puts many constraints on the sample environment and requires probing faster than the X-ray radiation damage occurs. This strongly limits the applicability of the method in studying the chemistry of colloidal nanomaterials. The objective of LINCHPIN is to investigate the emergence of electronic structure of nanomaterials in solution by hard X-ray photon-in-photon-out spectroscopy. To reach this very ambitious target, LINCHPIN consolidates an interdisciplinary engineering, spectroscopic and chemically driven effort. My group aim for developing micro-reactors, which will enable new fundamental insights related to the chemistry and electronic properties of the transition metal nitrides and sulfides. The main scientific goals are to study at the relevant time scales the kinetics and dynamics of: (a) short-lived molecular intermediate states and pre-nucleation clusters, (b) metal-sulfur and metal-nitrogen bond formation and their condensation in solution, (c) electronic structure changes during growth of nanostructures, and (d) concurrently interdependent electronic and chemical processes. The ultimate goal is to have a handle on designing and selecting, still in the reaction solution, the nanomaterials with the most promising electronic properties relevant for energy conversion and storage. Moreover, the proposed micro-reactors along with experimental spectroscopic protocols and the concurrent fundamental knowledge create a paradigm shift for in situ time-resolved experiments with an impact in many other fields ranging from catalysis, sustainable flow chemistry to biomedical applications.";1964375;1964375;ERC-2018-COG;/ERC-COG;UNIVERSITAET HAMBURG;DE;;;;1;0;0;1;0;0 220809;803486;FOODCULT;SIGNED;H2020-EU.1.1.;ERC-2018-STG;H2020;Food, Culture and Identity in Ireland, 1550-1650;2019-02-01;2024-01-31;;"FOODCULT is the first project to establish both the fundamentals of everyday diet, and the cultural ‘meaning’ of food and drink, in early modern Ireland. Exploring the period 1550-1650, one of major economic development, unprecedented intercultural contact, but also of conquest, colonisation and war, it focusses on Ireland as a case-study for understanding the role of food in the demonstration and negotiation of authority and power, and as a site for the development of emergent ‘national’ food cultures. Moving well beyond the colonial narrative of Irish social and economic development, however, it enlarges the study of food to examine neglected themes in Irish historiography, including gender, class, kinship and religious identities, as expressed through the consumption and exchange of food and drink. Taking advantage of recent archaeological discoveries and the unprecedented accessibility of the archaeological evidence, the project develops a ground-breaking interdisciplinary approach, merging micro-historical analytical techniques with science and experimental archaeology, to examine what was eaten, where, why and by whom, at a level of detail deemed impossible for Irish history. Such questions will be explored in a comparative British Isles context, situating Irish developments within a broader analytical framework, whilst moving English food historiography beyond its current insular focus. As a corollary, the project will produce the first major database of diet-related archaeological evidence for this period Mapping Diet: Comparative Food-Ways in Early Modern Ireland, while making accessible the only existing household accounts, a hugely significant, and previously overlooked, quantitative and qualitative source for dietary trends. These resources will shed light, not just on consumption patterns, but on Ireland’s broader economic and social development, whilst significantly furthering research agendas in early modern historical and archaeological scholarship.";1433133;1433133;ERC-2018-STG;/ERC-STG;THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN;IE;"UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN;ANGLIA RUSKIN UNIVERSITY HIGHER EDUCATION CORPORATION;INSTITUTE OF TECHNOLOGY SLIGO - ITS;UNIVERSITY OF DURHAM;UNIVERSITY OF BRISTOL";"IE;UK";;1;0;0;1;0;0 220945;824580;EU-Citizen.Science;SIGNED;H2020-EU.5.c.;SwafS-15-2018-2019;H2020;The Platform for Sharing, Initiating, and Learning Citizen Science in Europe;2019-01-01;2021-12-31;;"Citizen Science is a rapidly expanding and diversifying field of innovation with significant implications for, and potential benefits to, society, policy, and various academic research areas. This heterogeneity leads currently to a fragmented and not fully coordinated European Citizen Science landscape. The ambition of EU-Citizen.Science is to build, fill, and promote a sustainable platform and mutual learning space providing different tools, best practice examples and relevant scientific outcomes that are collected, curated, and made accessible to different stakeholders, ranging from interested citizens over scientific institutions up to politicians and public media in order to mainstream Citizen Science in Europe. This breakthrough will be pursued through three interconnected lines of activity: (i) coordination of citizen science actions and leveraging of existing resources in the presently fragmented landscape of Citizen Science in Europe, (ii) engagement of quadruple helix stakeholders at all levels (local, national and European), and (iii) creation of a mutual learning space and a set of comprehensive co-designed training modules for the different target audiences. Moreover, following a transparent, open and inclusive approach, EU-Citizen.Science will promote interdisciplinary, cross-border, cross-sector collaboration, and give rise to significant social innovation and new business models through the creation of new partnerships and the provision of novel sustainability-supporting tools. The EU.Citizen.Science project involves 14 partners and 9 third parties, representing 14 European Member States and a variety of stakeholders ranging from universities, NGOs, local authorities, CSOs and natural history museums, along with several other project supporters. Many of the partners are already engaged in other SwafS projects related to RRI, co-creation and citizen science, as well as numerous initiatives at national or local level.";1999878,75;1999878,75;H2020-SwafS-2018-1;/CSA;MUSEUM FUR NATURKUNDE - LEIBNIZ-INSTITUT FUR EVOLUTIONS- UND BIODIVERSITATSFORSCHUNG AN DER HUMBOLDT-UNIVERSITAT ZU BERLIN;DE;"UNIVERSITEIT LEIDEN;MYKOLO ROMERIO UNIVERSITETAS;THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN;NATURAL HISTORY MUSEUM;CONSERVATION EDUCATION AND RESEARCH TRUST;MINISTERIO DE ECONOMIA, INDUSTRIA Y COMPETITIVIDAD;INTERNATIONALES INSTITUT FUER ANGEWANDTE SYSTEMANALYSE;VEREIN DER EUROPAEISCHEN BURGERWISSENSCHAFTEN - ECSA E.V.;ZENTRUM FUR SOZIALE INNOVATION GMBH;ASSOCIATION EUROPEENNE DES EXPOSITIONS SCIENTIFIQUES TECHNIQUES ET INDUSTRIELLES;UNIVERSITY COLLEGE LONDON;VETENSKAP & ALLMANHET, VA;MUNICIPIO DE FIGUEIRA DE CASTELO RODRIGO";"NL;LT;IE;UK;ES;AT;DE;BE;SE;PT";;1;0;0;1;0;0 216644;800994;QSA;SIGNED;H2020-EU.1.2.3.;FETFLAG-02-2017;H2020;Quantum Coordination and Support Action;2017-12-01;2019-03-31;;"Quantum Technologies (QT) represent a disruptive technological shift with far-reaching applications, including secure communication networks, ultra-sensitive sensors and fundamentally new paradigms of simulation and computation. In each of these applications, quantum technologies could result in revolutionary improvements in terms of capacity, sensitivity and speed, and be the decisive factor for success in many industries and markets. The immense potential of this interdisciplinary field has led the European Commission to announce the launch of a FET Flagship on Quantum Technologies (“Quantum Flagship”) in 2018 and to appoint an independent High-Level Steering Committee to give recommendations on its setup. Based on these recommendations and building on previous coordination efforts, we propose the Quantum Coordination and Support Action (QSA) whose primary goal is to prepare the ground for a successful launch of the Quantum Flagship. The QSA initiative is a timely, important and necessary planning step to make sure the full potential of the Quantum Flagship can be attained right from its start. For this to happen, we set out to achieve the following objectives: 1. Facilitate a goal-driven, federated effort to set up the Quantum Flagship, 2. Increase awareness of QT in Europe, and 3. Support detailing and implementing the Flagship’s organisational structure. We believe that these objectives are best achieved by acting in a transparent and inclusive way, ensuring commitment from all key stakeholders (academia, industry and EU and national policy makers) to the Quantum Flagship, and we have structured our work plan accordingly to succeed within the scope and duration of the Coordination and Support Action.";500000;500000;H2020-FETFLAG-02-2017;/CSA;FORSCHUNGSZENTRUM JULICH GMBH;DE;"ROBERT BOSCH GMBH;UNIVERSITE DE GENEVE;UNIVERSITAET ULM;THALES SA;UNIVERSITAT DES SAARLANDES";"DE;CH;FR";;1;0;0;1;0;0 198675;666068;CsnCRL;SIGNED;H2020-EU.1.1.;ERC-ADG-2014;H2020;The molecular basis of CULLIN E3 ligase regulation by the COP9 signalosome;2016-01-01;2020-12-31;;"Specificity in the ubiquitin-proteasome system is largely conferred by ubiquitin E3 ligases (E3s). Cullin-RING ligases (CRLs), constituting ~30% of all E3s in humans, mediate the ubiquitination of ~20% of the proteins degraded by the proteasome. CRLs are divided into seven families based on their cullin constituent. Each cullin binds a RING domain protein, and a vast repertoire of adaptor/substrate receptor modules, collectively creating more than 200 distinct CRLs. All CRLs are regulated by the COP9 signalosome (CSN), an eight-protein isopeptidase that removes the covalently attached activator, NEDD8, from the cullin. Independent of NEDD8 cleavage, CSN forms protective complexes with CRLs, which prevents destructive auto-ubiquitination. The integrity of the CSN-CRL system is crucially important for the normal cell physiology. Based on our previous work on CRL structures (Fischer, et al., Nature 2014; Fischer, et al., Cell 2011) and that of isolated CSN (Lingaraju et al., Nature 2014), We now intend to provide the underlying molecular mechanism of CRL regulation by CSN. Structural insights at atomic resolution, combined with in vitro and in vivo functional studies are designed to reveal (i) how the signalosome deneddylates and maintains the bound ligases in an inactive state, (ii) how the multiple CSN subunits bind to structurally diverse CRLs, and (iii) how CSN is itself subject to regulation by post-translational modifications or additional further factors. The ERC funding would allow my lab to pursue an ambitious interdisciplinary approach combining X-ray crystallography, cryo-electron microscopy, biochemistry and cell biology. This is expected to provide a unique molecular understanding of CSN action. Beyond ubiquitination, insight into this >13- subunit CSN-CRL assembly will allow examining general principles of multi-subunit complex action and reveal how the numerous, often essential, subunits contribute to complex function.";2200677;2200677;ERC-2014-ADG;/ERC-ADG;FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION;CH;;;;1;0;0;1;0;0 194333;645628;METCOPH;SIGNED;H2020-EU.1.3.3.;MSCA-RISE-2014;H2020;Metallocomplexes of macrocyclic compounds for photonic devices;2015-01-01;2018-12-31;;"The key objective of the METCOPH multidisciplinary project is to intensify and consolidate cooperation between several research groups from member states and third countries on topics within the field of fundamental interdisciplinary science. The project combines the basic ideas of organic chemistry, solid state physics, photochemistry and spectroscopy of metallocomplexes of macrocyclic compounds (MMC) for applications in quantum information processing, sensing, switching and amplification. The project aims at focusing mutual efforts of five research groups with extended and complementary competence in their respective research fields and at gathering multidisciplinary and complementary expertise in chemical engineering and investigation of spectroscopy and photochemistry of MMCs for future design of photonic devices (e.g. organic light emitting devices – OLEDs, light emitting electrochemical cells – LECs, sensors, light emitting transistors) based on above mentioned compounds. The physical and chemical mechanisms of manipulation of optical response for these novel compounds will be revealed and analyzed with involving diverse spectroscopic approaches including steady-state and transient absorption, site-selective high-resolution luminescence, Raman scattering, atomic force microscopy and single-objects detection methods at different temperatures ranging from 1.2 K to ambient temperature. The expected results involve fabrication and chemical/photophysical characterisation of MMCs based on various core metals and incorporating various functional organic ligands. One of the key technologies will rely on driving optical transistor with CW and pulsed lasers and will make use of simultaneous excitation of singlet and triplet states of the metallocomplexes of macrocyclic compounds. The new information gained for these newly synthesized MMC systems will have impact on the engineering of novel functional MMCs for application in nanotechnology and photonic devices.";688500;688500;H2020-MSCA-RISE-2014;/MSCA-RISE;INSTYTUT CHEMII FIZYCZNEJ POLSKIEJ AKADEMII NAUK;PL;"UNIVERSITAET REGENSBURG;TEL AVIV UNIVERSITY";"DE;IL";;1;0;0;1;0;0 218757;822615;CO3;SIGNED;H2020-EU.3.6.2.2.;DT-TRANSFORMATIONS-02-2018-2019-2020;H2020;Digital Disruptive Technologies to Co-create, Co-produce and Co-manage Open Public Services along with Citizens;2019-01-01;2021-12-31;;"CO3 aims at assessing the benefits and risks of disruptive technologies, namely: blockchain, augmented reality, geolocated social network, liquid democracy tools and gamification, in the co-creation, co-production and co-management of public services with citizens as PAs partners. Augmented Reality becomes a single shared layer on the urban paysage and part of citizen’s public life, AR enables manipulation of financial objects built on blockchains, information sharing on a map, online deliberations and so constitutes an infrastructure for service co-production by citizens. CO3 pilots the technologies’ ecosystem of in three sites. It evaluates the outcomes of the new interaction model between PA and citizens under a set of metrics in three dimensions : 1) social and cultural: citizen engagement, change in relationship with public servants; 2) economic: value of services produced, effects on workplaces, consumptions and economic sustainability; 3) legal: legal implications for PA including privacy and data protection. CO3 will devise a business plan ensuring long term sustainability for the PAs on the basis of the metrics applied on the pilots’ data. CO3 is a participative and interdisciplinary project, the Consortium involves: University of Torino (IT)(Computer Science, Economics, Sociology and Law), ISMB private research center (IT), Fundación Universitaria Balmes (ES), Institut de Recherche et d’Innovation of Centre Pompidou (FR), and OpenLab Athens (EL), with its Laboratory of the Digital Commons. It also involves three highly innovative SMEs: Brainbot, leaders in the Ethereum Blockchain development(DE), FlexiGuided (DE), the company that created LiquidFeedback, Geomotion (ES) working on augmented reality and location-based technologies. Municipality of Torino (IT) together with the Neighbourhood Houses, Municipality of Athens (EL) via its public company DAEM and the Municipalities of the Plaine Commune in Paris (FR) will be the pilot sites.";3281712,5;3281712;H2020-SC6-TRANSFORMATIONS-2018;/RIA;UNIVERSITA DEGLI STUDI DI TORINO;IT;"FLEXIGUIDED GMBH;FUNDACIO UNIVERSITARIA BALMES;DIMOS ATHINAION EPICHEIRISI MICHANOGRAFISIS;GEOMOTION GAMES SL;INSTITUT DE RECHERCHE ET D'INNOVATION;ANOIXTO ERGASTIRIO ATHINAS ASTIKI MI KERDOSKOPIKI ETAIREIA;BRAINBOT TECHNOLOGIE AG;COMUNE DI TORINO;ISTITUTO SUPERIORE MARIO BOELLA SULLE TECNOLOGIE DELL'INFORMAZIONE E DELLE TELECOMUNICAZIONI ASSOCIAZIONE;FONDAZIONE LINKS - LEADING INNOVATION & KNOWLEDGE FOR SOCIETY";"DE;ES;EL;FR;IT";;1;0;0;1;0;0 215681;798830;MAGNET-CELLPATCH;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Multimodal magnetic cellular-patches with synergistic effects for high performance theranostics;2019-09-01;2021-08-31;;"The key goals of the MAGNET-CELLPATCH project are: a) the training of a talented experienced researcher, Dr. Castellanos-Rubio, in the fast growing fields of nanotechnology, microfabrication, biomedicine and healthcare industry, in which the host and partner institutions have an extensive knowledge and expertise; and, b) the development, optimisation and evaluation of cost-efficient multimodal magnetic cellular-patches for high performance theranostics. The interdisciplinary training program includes the use of advanced characterisation techniques, as XAS and SAXS, and the evaluation of the material in therapy (hyperthermia-chemotherapy) and diagnosis (MRI) of colorectal cancer. The fellow is a skilled researcher that during her undergraduate and postgraduate career has gained strong experience in the fabrication and characterization of biocompatible magnetic nanoparticles and inorganic-polymeric microstructures with magnetothermal properties. To further boost her career, she needs to gain expertise in sophisticated data-capture instrumentation (such as synchrotron radiation sources), in in-vitro and in-vivo experimental studies and in MRI technique, in which the UPV/EHU has a world-recognised expertise. Moreover, through secondments at academic and industrial co-hosts, at the UCL and NIT respectively, she will gain additional training in preclinical experiments in the field of magnetic-drug-targeting and in production protocols of medical devices, scaling-up options, cost-reduction strategies, quality-controls and market-ready items designs. This multidisciplinary project explicitly addresses a world-wide societal challenge in health, namely, the development of new materials for cancer treatment. In addition, it will also increase the fellow´s supervision and teaching experience, project and intellectual property management expertise, research funding and proposal writing, which will assist her in acquiring necessary competences to reach professional maturity.";158121,6;158121,6;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA;ES;;;;1;0;0;1;0;0 209296;749229;ModelingCommonGround;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Modeling Common Ground;2017-09-11;2020-09-10;;"Language is inherently ambiguous. The meaning of words and sentences depends on the identity of the communicative partners and the nature of the context. In simple behavioral experiments children and adults can use a wide variety of social-contextual cues (jointly known as “common ground”) to interpret ambiguous utterances. But this limited empirical evidence – especially in the developmental context – does not live up to the theoretical importance of common ground: In theory, common ground is not only involved in online language use but it is also a necessary prerequisite to learn language in the first place. Studying the development of children’s ability to form and use common ground is therefore crucial to understand the psychological foundation of language. It is still unknown how both adults and children integrate different social-contextual cues in complex, naturalistic interactions. Bayesian modeling provides a mathematical framework for formalizing theoretical assumptions about this interaction and deriving quantitative predictions about new experimental situations. This project will unite developmental and computational approaches. The key objective is to find out what constitutes common ground at different ages and how it informs language learning across development. I will develop mathematical models and behavioral experiments in parallel to obtain quantitative predictions for different forms of interactions between social-contextual cues. By comparing these predictions to data from early children’s word learning at different stages of development, I will be able to empirically evaluate the theoretical importance of the different components of common ground. The interdisciplinary focus of the project at the intersection of psychology, linguistics and computer science will open up new avenues for the empirical study of language use and language learning.";239860,8;239860,8;H2020-MSCA-IF-2016;/MSCA-IF-GF;UNIVERSITAET LEIPZIG;DE;;;;1;0;0;1;0;0 221293;802362;BIT-ACT;SIGNED;H2020-EU.1.1.;ERC-2018-STG;H2020;Bottom-up initiatives and anti-corruption technologies: how citizens use ICTs to fight corruption;2019-07-01;2024-06-30;;"Corruption is a global challenge that affects the lives of millions of citizens. In the past decade, Information and Communication Technologies (ICTs) have become indispensable tools in the fight to reduce corruption, especially when employed from the bottom-up by civil society organizations. While pioneering initiatives in this direction have flourished, to date we only have unsystematic and descriptive evidence regarding how they work and the associated consequences. With the objective of significantly advancing knowledge on this topic, BIT-ACT will open a new line of inquiry by investigating what I call anti-corruption technologies (ACTs) to: (1) assess how civil society organizations engage with ACTs to counter corruption, (2) appraise how ACTs enable intersections between bottom-up and top-down efforts against corruption, and (3) evaluate how ACTs blend with the transnational dimension in the struggle against corruption. Based on an interdisciplinary framework that combines corruption studies, science and technology studies and social movement studies, BIT-ACT will use the constructivist grounded theory method to analyze a combination of textual and visual data in a comparative and transnational research design including nine countries – Algeria, Bangladesh, Brazil, Estonia, India, Italy, Spain, Ukraine, Uruguay. BIT-ACT will be groundbreaking in three ways. At the theoretical level, it will expand the debate on anti-corruption providing grounded concepts and models to explain ACTs; at the empirical level, it will advance knowledge on how the usage of ACTs is changing the relationship between citizens and democratic institutions; at the methodological level, it will innovate in the use of grounded theory assessing a new standard for cross-national comparative grounded theory. Finally, BIT-ACT will produce sound and useful knowledge for the stakeholders involved in the fight against corruption worldwide by suggesting how to best employ ICTs from the bottom-up.";1489115;1489115;ERC-2018-STG;/ERC-STG;ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA;IT;;;;1;0;0;1;0;0 214774;777455;IoT4Industry;SIGNED;"H2020-EU.2.3.2.2.;H2020-EU.2.3.2.3.";INNOSUP-01-2016-2017;H2020;Towards smarter means of production in European manufacturing SMEs through the use of the Internet of Things technologies;2018-04-01;2020-09-30;;The proportion of the manufacturing industry is currently decreasing in developed European countries’ GDP. Industry 4.0 - also called smart manufacturing, digital industry or industry of the future – provides several technological responses to the challenging competitive market. Indeed, the integration of the Internet of Things and related components - Cyber-Physical Systems (CPS), Digital Security, Cloud Computing and Big Data - in manufacturing SMEs will improve efficiency and flexibility in production and consumption. However, it requires a more integrated and cooperative approach due to the high interdisciplinarity which has been introduced. Above all, not all manufacturing companies, and in particular SMEs, have access to smarter means of production, due to costs and efforts in the integration and implementation, possible aversion or readiness to ICT technologies, and other obstacles related to cyber and physical security. The IoT4Industry project connects 3 Information and Communication Technologies (ICT) clusters having strong competences in IoT with 4 Advanced Manufacturing clusters having access to tool manufacturers and manufacturing SMEs in order to encourage cross-border and cross-sectorial collaboration between SMEs from these two sectors. Starting from the analysis of needs in manufacturing SMEs from diverse sectors in Europe (aerospace, automotive, medicine, ...) on the one hand, and the IoT technology offer on the other hand, the project will put in place favourable framework conditions to enable matchmaking and encourage the creation of smarter manufacturing tools and their integration in manufacturing SMEs. A hundred of support cases involving SMEs corresponding to different development stages (feasibility, prototyping, demonstration) will be selected through a call for proposals to receive funding and support, in view of further developing this new industrial value chain in European SMEs and improve their competitiveness on the global stage.;4962500;4852812,5;H2020-INNOSUP-01-2017-twoStage;/IA;POLE SOLUTIONS COMMUNICANTES SECURISEES;FR;"ARVE INDUSTRIES HAUTE SAVOIE MONT BLANC;INNO TSD;MICROTEC SUDWEST EV;CENTRO SERVIZI INDUSTRIE SRL;POLE MECATECH;DSP VALLEY VZW;THE MANUFACTURING TECHNOLOGY CENTRE LIMITED";"FR;DE;IT;BE;UK";;1;0;0;1;0;0 215642;798479;MRRI-MENA;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Migrant and Refugee Rights Index for the Middle East and North Africa;2019-08-05;2021-08-04;;"As of 2000 the stock of migrants in the Global South has been growing at a faster rate than in the Global North, and as of 2016 countries in the Global South host eighty-four per cent of the world’s refugees. Yet the majority of academic literature on migration examines movement from the Global South to the Global North, and there is significantly less theorization about how host countries in the Global South treat migrants and refugees. My project addresses this gap through an examination of host state policies toward and treatment of migrants and refugees in the Middle East and North Africa (MENA), a region that has seen increasing patterns of migrant and refugee settlement in the last three decades. My project will develop an index that rigorously measures host state policies toward migrants and refugees using a minority rights framework. The results of this study will provide MENA host states, European donor states, and international humanitarian organizations with a useful index tool for highlighting areas in which legal and social measures should be strengthened via targeted funding and capacity-building to counteract exclusion and provide stronger protection for migrants and refugees. This project directly corresponds to the Horizon 2020 policy priority of creating inclusive, innovative and reflective societies through the promotion of coherent and effective cooperation with third countries, and by addressing issues of identities, tolerance and cultural heritage. Completing this research as a postdoctoral scholar at the Institute for Minority Rights at EURAC will equip me with skills in the use of a multi and interdisciplinary approach combining legal, political and sociological research in order to address the complex issue of minority and migrant rights for this project and going forward as a scholar. In particular, I will gain exposure to the Institute’s use of theoretical frameworks for developing indicators that measure minority rights protection.";180277,2;180277,2;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;ACCADEMIA EUROPEA DI BOLZANO;IT;;;;1;0;0;1;0;0 214175;796918;LocalCom;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Digital Local Public Sphere and Local Communication Online: A Comparative Study of Four European countries;2019-02-22;2021-02-21;;"The study of local communication in the digital age is an important subject area, as a thriving public dialogue and deliberation online enhances local democracies and engagement in local matters. However, our understanding of local communication online and how practices of different local communities vary is limited, as most research in the field explores online communication at national or international level. The aim of this project is to conduct a comparative study on the democratic potentials and challenges of local communication online and on the key features of digital local public spheres in four European countries. The objectives of the project are to: 1) develop a framework for the study of digital local public sphere; 2) analyse and compare online communication of local communities in Italy, Norway, Poland and the UK; 3) analyse and compare key features of digital local public spheres of local communities in Italy, Norway, Poland and the UK; 4) develop policy recommendations to foster strong and inclusive digital local public spheres in local communities. With these objectives the study will not only provide a theoretical contribution but also inform policy debates and have the potential to influence communicative practices. A mixed method approach will be applied for the empirical research, which will involve case study analysis of local communities in the four countries. The methods will include content analysis, interviews and social media network analysis. The project will be carried out at the Centre for Research on Communities and Cultures, Canterbury Christ Church University, a specialist centre in the study of local communities in the digital age with fitting training profile. The fellowship will expand the theoretical and methodological competences of Professor Biernacka-Ligiêza, and diversify her skills and knowledge through its interdisciplinary approach, impact on both academic and non academic beneficiaries and international mobility.";195454,8;195454,8;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;CANTERBURY CHRIST CHURCH UNIVERSITY LTD;UK;;;;1;0;0;1;0;0 210540;740516;NonSequeToR;SIGNED;H2020-EU.1.1.;ERC-2016-ADG;H2020;Non-sequence models for tokenization replacement;2017-10-01;2022-09-30;;"Natural language processing (NLP) is concerned with computer-based processing of natural language, with applications such as human-machine interfaces and information access. The capabilities of NLP are currently severely limited compared to humans. NLP has high error rates for languages that differ from English (e.g., languages with higher morphological complexity like Czech) and for text genres that are not well edited (or noisy) and that are of high economic importance, e.g., social media text. NLP is based on machine learning, which requires as basis a representation that reflects the underlying structure of the domain, in this case the structure of language. But representations currently used are symbol-based: text is broken into surface forms by sequence models that implement tokenization heuristics and treat each surface form as a symbol or represent it as an embedding (a vector representation) of that symbol. These heuristics are arbitrary and error-prone, especially for non-English and noisy text, resulting in poor performance. Advances in deep learning now make it possible to take the embedding idea and liberate it from the limitations of symbolic tokenization. I have the interdisciplinary expertise in computational linguistics, computer science and deep learning required for this project and am thus in the unique position to design a radically new robust and powerful non-symbolic text representation that captures all aspects of form and meaning that NLP needs for successful processing. By creating a text representation for NLP that is not impeded by the limitations of symbol-based tokenization, the foundations are laid to take NLP applications like human-machine interaction, human-human communication supported by machine translation and information access to the next level.";2500000;2500000;ERC-2016-ADG;/ERC-ADG;LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN;DE;;;;1;0;0;1;0;0 205602;722096;DYNACOMP;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2016;H2020;Dynamic behaviour of composite materials for next generation aeroengines;2016-09-01;2020-08-31;;The main objective of the DYNACOM (Dynamic behaviour of composite materials for next generation aeroengines) training network is to set up a European Industrial Doctorate (EID) programme on the design of the next generation of structural composite materials for high strain rate applications. This will be achieved by the development of a consistent, physically based multiscale simulation strategy informed by the dynamic properties of the constituents (fibre, matrix and fiber/matrix interface) measured with a novel micromechanical testing methodology. Two of the major milestones of this EID are: (1) to offer early stage researchers (ESRs) a multidisciplinary and intersectorial training with the objective of establishing a new design paradigm in structural design of composite materials and (2) to provide the European industry with new tools towards a knowledge-base incorporation of composite materials into new components, without the need of inefficient and expensive traditional trial and error approaches. In this sense, the technological focus is put into the introduction of new composite components into the next generation of aeronautical engines, but the implications are numerous in other sectors where composite materials have been identified as a key enabling technology, such as in transport, energy generation and biomedical applications. To accomplish this, the programme brings together one research institution, two industrial partners, one academic institution and a non-profit organization. The joint academic and industrial training program offered by this EID will ensure that the innovative aspects of the research work find a quick industrial integration and will provide the early stage researchers with a truly interdisciplinary and intersectoral training, enhancing their employability and career perspectives.;495745,92;495745,92;H2020-MSCA-ITN-2016;/MSCA-ITN-EID;FUNDACION IMDEA MATERIALES;ES;HEXCEL COMPOSITES LTD;UK;;1;0;0;1;0;0 205390;722842;PlaMatSu;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2016;H2020;Plant-inspired materials and surfaces;2016-10-01;2020-09-30;;"Modern polymeric materials and surfaces are a corner-stone of Europe’s economy and research activities. Materials with novel properties are therefore of great interest. Nature provides us with a rich pool of multifunctional materials that can act as concept generators for synthetic materials. The uppermost layer of plant leaves and flower petals, the cuticle, is a smart polymer composite which a variety of functions, ranging from controlled regulation of water permeability, to the formation of structural colour and sticky or non-friction surfaces. The overall aims of PlaMatSu are (1) to address the challenge of creating new functional polymeric materials and surfaces by studying structure formation and function-property relationships in cuticles and (2) to educate the next generation of scientists who have the necessary interdisciplinary knowledge for turning scientific results into innovation. To reach its aims PlaMatSu will: - Train 9 Early Stage Researchers (ESRs) at PhD level in a network of multi-disciplinary labs composed of biologists, physicists, and chemists. The expertise of the supervisors includes evolution and plant biology, responsive polymeric materials, polymer chemistry, surface sciences, optical properties of materials and polymer physics. - Provide ESRs with training in technology transfer, innovation, management, writing, interactions with the public, and intellectual property rights via a set of dedicated workshops. - Offer to each ESR secondments in academia, and most importantly, in private companies. Through latter ESRs will be exposed to the research and development environments of top companies in the chemical, food, polymer processing and scientific services industry. New bio-inspired materials offer great potential for knowledge creation and innovation. After having completed the research and doctoral program proposed by PlaMatSu, ESRs will be ready to embark on a career in academia or industry.";2363193,36;2363193,36;H2020-MSCA-ITN-2016;/MSCA-ITN-ETN;UNIVERSITE DE FRIBOURG;CH;"THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;ALBERT-LUDWIGS-UNIVERSITAET FREIBURG";"UK;DE";;1;0;0;1;0;0 197851;642676;CardioFunXion;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2014-EID;H2020;Towards a novel paradigm for cardiac function assessment from imaging;2015-09-01;2019-08-31;;"Cardiovascular diseases have been defined as a top priority within H2020. Although diagnostic approaches and therapies have drastically improved over the last decennia, effective, validated and auditable tools for the integrated assessment of cardiac function in clinical practice have yet to be developed. CardioFunXion will contribute to a novel paradigm for integrated assessment, combining (image-based) measurements with (model-based) incorporation of physiological knowledge and clinical guidelines. Project outcomes will include validation (improving reproducibility) and integration (simplifying interpretation) cardiac function assessment tools. These novel approaches will be implemented by connecting the imaging industry with the academic and clinical worlds through a combination of four PhD research projects with dedicated training initiatives to develop an inter-sectorial and interdisciplinary culture. The individual research projects are entitled: Longitudinal assessment of function; Fusion of heterogeneous measurements into physiological plausible representations; Open reference databases/tools for multimodal validation of strain; Novel approach for evidence based classification of heart failure etiologies. The consortium is composed of a large Medical Imaging Company (Philips), a University (UPF), and 2 Clinical Centres (IDIBAPS/CHUC), thus encompassing the whole spectrum of relevant multi-disciplinary multi-sectorial Europe-wide expertise. The early stage researchers in the project will thus benefit from a holistic view of the topic and gain first-hand experience in academic, industrial and clinical research and development.";1021497,12;1021497,12;H2020-MSCA-ITN-2014;/MSCA-ITN-EID;UNIVERSIDAD POMPEU FABRA;ES;PHILIPS FRANCE SAS;FR;;1;0;0;1;0;0 196788;639300;MechanoFate;SIGNED;H2020-EU.1.1.;ERC-StG-2014;H2020;From mechanical stress to vascular fate;2016-01-01;2020-12-31;;"In the vascular system, cell phenotype and fate are driven by the mechanical environment. Whereas physiological mechanical stress defines and stabilizes normal cell phenotype, aberrant mechanical signals trigger phenotypic alteration, leading to inflammation and vascular remodelling. Despite recent advances, how mechanical cues impact gene expression to specify cell phenotype remains poorly understood. Our hypothesis is that mechanical stresses are transmitted to the nucleus where they activate signaling pathways, which in turn regulate gene expression, but what are these mechanotransduction mechanisms occurring within the nucleus? Besides, while most vascular cells respond to mechanical force, Resident Stem Cells (RSCs) are virtually insensitive and remain undifferentiated despite constant cyclic stretch. What are the molecular mechanisms which protect RSCs from stretch-induced differentiation? To answer these questions, we designed an interdisciplinary proposal which gathers biophysical, biochemical and genetic assays, with the following objectives: I) To determine how nuclear mechanotransduction pathways regulate vascular cell phenotype in response to mechanical cues. By combining proteomic and biophysical assays, we will identify nuclear proteins that are post-translationally modified in response to mechanical stress, then we will determine their contribution to gene expression regulation and vascular cell differentiation. II) To identify the molecular mechanisms which protect RSCs from stretch-induced differentiation. We will identify differentially expressed force-bearing structural elements in RSCs compared to more differentiated vascular cells and we will evaluate their impact on gene expression, stress transmission, RSC differentiation and blood vessel formation. The proposed project will yield new insights in different areas of life science from cell biology to potential identification of new therapeutic targets in cardiovascular and regenerative medicine.";1498412,5;1498412,5;ERC-2014-STG;/ERC-STG;INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE;FR;;;;1;0;0;1;0;0 197084;646714;RG;SIGNED;H2020-EU.1.1.;ERC-CoG-2014;H2020;Reading Global. Constructions of World Literature and Latin America;2015-09-01;2020-08-31;;"The debate on world literature is among the most significant cultural historical controversies of our time. This contribution to the debate aims to pursue two goals in particular: a) A groundbreaking theoretical approach to the current shift in focus of the concept of World Literature that will involve both the displacement of Eurocentric forms of knowledge and a comprehensive review of selection processes in a globalized publishing world. b) An innovative investigation of the production and selection of literature that eschews an established canon as a point of departure. This approach is based, among other things, on newly available archival materials from publishing houses active on the international market, which will provide information on mechanisms of exclusion in the global book market. Informed by multiple critical perspectives on current theories, this five-year, six-member project will investigate the implicit selection mechanisms involved in the global circulation of literature, which touch on the material, economic, and visual dimensions of these processes and have so far received little to no attention. The project takes as its focus the exemplary case of Latin American literatures and their global circulation for the period from 1959 to the present. Unique among global regions in its comparative cultural, historical, and political homogeneity, Latin America offers the opportunity to investigate processes of external projection (exoticization), mechanisms of exclusion, and current transformations of the global market of culture. This interdisciplinary project combines literary studies methodologies with a cultural studies perspective on the World Literature debate and likewise integrates approaches from visual studies and economics. The global comparative analysis of publishing policies will provide groundbreaking knowledge on the processes of reception, canon formation and exclusion in the international circulation of literature.";1965250;1965250;ERC-2014-CoG;/ERC-COG;UNIVERSITAET ZU KOELN;DE;;;;1;0;0;1;0;0 218159;788308;Self-Control;SIGNED;H2020-EU.1.1.;ERC-2017-ADG;H2020;Interplay between genetic control and self-organization during embryo morphogenesis;2018-11-01;2023-10-31;;"Morphogenesis seeks to understand how information and mechanics emerge from molecular interactions and how they are regulated in space and time. Two parallel legacies are now intertwined: the conceptual framework of developmental patterning that explains how cells acquire positional information during development and control cell behaviors, and the description of biological processes in physical terms. The current framework explains how genetic and biochemical information controls cellular mechanics, in particular contractility mediated by actomyosin networks, and thus cell and tissue shape changes. However, newly reported contractile dynamics, namely pulses, flows and waves, cannot be explained in this framework: they are self-organized in that they depend on local mechano-chemical interactions and feedback that cannot be accounted for by upstream genetic control. This project will explore the interplay between genetic control and self-organization in Drosophila embryos. We will study the emergence of multicellular flow and the mechanism of newly characterized tissue-level trigger wave dynamics associated with endoderm invagination, a poorly studied process. We will ask: 1) how do patterns of apical and basal contractility drive cell dynamics; 2) what is the contribution of geometrical feedback, e.g. tissue curvature, in amplifying the effect of contractile asymmetries; and 3) what is the nature of mechanical feedback and cell spatial coupling underlying trigger wave dynamics in the tissue? We will use an interdisciplinary approach, combining live imaging, capturing the 3D shape of cells/tissues, genetic/optogenetic/mechanical perturbations and theoretical/computational methods to model mechanics and geometry. We expect to unravel how organized multicellular dynamics emerge from genetic, mechanical and geometric “information”, and feedback during morphogenesis. This work will shed new light on a variety of morphogenetic processes occurring during development.";2862571;2862571;ERC-2017-ADG;/ERC-ADG;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FR;;;;1;0;0;1;0;0 218050;813786;EVOdrops;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2018;H2020;directed EVOlution in DROPS;2018-10-01;2022-09-30;;"Natural evolution is a powerful process that has given rise to the functionally diverse set of proteins present in all living systems. Repetitive rounds of mutation, selection and amplification have optimised nature’s catalysts, the enzymes, to perform an enormous range of different reactions. However, natural evolution has driven the optimisation of enzymes subjected to living functions of microorganisms, according to ill-defined and fluctuating external conditions and is not suitable for industrial processes since it lacks of control of selection pressure. In EVOdrops, we will use directed evolution to overcome these limitations. It is a synthetic, man-made approach of evolution, aiming at improving living systems based on predefined needs, controlling the external selection pressure. While natural evolution took billions of years to optimise macromolecules, directed evolution – to be efficient in an industrial process – requires both the generation of genetic diversity and ultra-high throughput screening capabilities to recover the variants of interest. We will develop and optimise these tools using the ground-breaking potential of droplet-based microfluidics for high-throughput experimentation and the fine control of gene library construction. EVOdrops, a European training network, will bring together the leading research scientists, laboratories and industries in Europe with outstanding expertise in protein engineering and microfluidics and 13 early stage researchers. We will offer an extensive multi- and interdisciplinary training to ensure that they can solve these urgent and unmet challenges in biotechnology and biomedicine. We will use a multidisciplinary approach combining soft matter, microfluidics and chemical biology to design solutions for the selection of new enzymes of industrial and therapeutic interest. In the future, our approaches can be generalised to challenges involving high-throughput miniaturised biochemical or cell-based assays.";3452422,98;3452422,98;H2020-MSCA-ITN-2018;/MSCA-ITN-ETN;UNIVERSITY OF GLASGOW;UK;"BIOMILLENIA;THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;TECHNISCHE UNIVERSITAET MUENCHEN;INSTYTUT CHEMII FIZYCZNEJ POLSKIEJ AKADEMII NAUK;UNIVERSITE CATHOLIQUE DE LOUVAIN;VILNIAUS UNIVERSITETAS;EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH;UAB THERMO FISHER SCIENTIFIC BALTICS;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;UNIVERSITE PARIS DESCARTES";"FR;UK;DE;PL;BE;LT;CH";;1;0;0;1;0;0 217810;813144;REAL-NET;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2018;H2020;REAL-time monitoring and mitigation of nonlinear effects in optical NETworks;2019-01-01;2022-12-31;;The exponential surge in the global data traffic driven by the skyrocketing proliferation of different bandwidth-hungry on-line services, such as: cloud computing, on-demand HD video streams, on-line business analytics and content sharing, sensor networks, machine-to-machine traffic arising from data-centre applications, the Internet of Things, and various other broadband services, brings about the escalating pressure on the speed (capacity) and quality (bit error rate) characteristics of information systems. It is well recognized nowadays that rapidly increasing data rates in the core fibre communication systems are quickly approaching the limits of current transmission technologies, many of which were originally developed for communication over linear (e.g. radio) channels. It is widely accepted that the nonlinear transmission effects in optical fibre represent now a major limiting factor in modern fibre-optic communication systems. Nonlinear properties make optical fibre channels considerably different from wireless and other traditional linear communications channels. There is a clear need for development of radically different methods for coding, transmission, and (pre & post) processing of information that take the nonlinear properties of the optical fibre into account and for training of a new generation of engineers with expertise in: optical communications, nonlinear science methods, digital signal processing (DSP), design of implementable algorithms. From the industry perspectives, design of practical and implementable processing algorithms requires knowledge of ASICs and real world conditions and restrictions. The mutli-national & multi-interdisciplinary REAL-NET project will provide timely doctoral training for 6 PhD students through industry relevant research in the fast growing area of high practical relevance and will lead to development of novel practically implementable disruptive techniques for fibre-optic communications.;1657758,96;1657758,96;H2020-MSCA-ITN-2018;/MSCA-ITN-EID;ASTON UNIVERSITY;UK;"CORIANT R&D GMBH;INSTITUT MINES-TELECOM;UNIVERSITAT POLITECNICA DE CATALUNYA";"DE;FR;ES";;1;0;0;1;0;0 218275;823902;OPEN;SIGNED;H2020-EU.1.3.3.;MSCA-RISE-2018;H2020;Outcomes of Patients’ Evidence With Novel, Do-It-Yourself Artificial Pancreas Technology;2019-02-01;2022-01-31;;Type 1 diabetes is a rare but highly challenging chronic condition which often leads to lowered life expectancy and greatly diminished quality of life even amongst those patients who are the most diligent and proactive in the practice of disease self-management. In recent years, there has been a growing movement of ‘patient innovators’ leading the development of self-built or ‘do-it-yourself’ artificial pancreas systems (DIYAPS), which help to automate day-to-day decision making needed for successful self-management. There is prima facie evidence to suggest that such systems can lead to improvements in glucose outcomes that far exceed those offered by the most state-of-the-art commercially available solutions. The aim of this RISE project is to tap into the expertise and knowledge shared by these communities by bringing together an intersectoral and interdisciplinary research team consisting of patient innovators, academic researchers, healthcare professionals (HCPs) and NGOs to establish an empirical evidence base surrounding the impact of DIYAPS. The exciting programme of research includes training and networking for participating staff designed to encourage inter-disciplinary thinking and broaden career horizons, while the dissemination and public outreach activities will ensure that project findings reach key stakeholders, such as policymakers, HCPs and industry, both within Europe and beyond. The key outcomes of this project will include a new model of knowledge co-creation and an evidence-base surrounding the potential scale-up of DIYAPS solutions that will have profound implications for those living with chronic conditions, their families, as well as healthcare systems and European society as a whole.;1021200;1021200;H2020-MSCA-RISE-2018;/MSCA-RISE;UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN;IE;"REGION HOVEDSTADEN;DEDOC LABS GMBH;CHARITE - UNIVERSITAETSMEDIZIN BERLIN;T1INTERNATIONAL;FEDERATION INTERNATIONALE DU DIABETE REGION EUROPE AISBL";"DK;DE;UK;BE";;1;0;0;1;0;0 217943;812968;PERICO;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2018;H2020;Peroxisome Interactions and Communication;2018-10-01;2022-09-30;;"PERICO fosters education of ESRs in a project to uncover how a central metabolic organelle, the peroxisome, participates in controlling cellular metabolism. It trains 15 ESRs at world-leading academic institutions, including university hospitals, and companies, thus forming strong interdisciplinary links between industry, life and medical sciences, and end-users. PERICO aims to train a new generation of highly qualified ESRs with entrepreneurial competencies in modern Life Sciences through state-of-the-art research projects focusing on the communication between peroxisomes and the rest of the cell – required to enable optimal metabolic decisions - and to use this knowledge to develop novel leads for drug discovery and therapies for a growing list of serious human diseases in which peroxisomes have been implicated. The new field on organelle communication requires highly skilled scientists who have expert knowledge on more than one discipline (e.g. cell biology, biochemistry, systems biology and medical sciences), more than one type of cell organelle or more than one model organism to optimally translate their research data to other disciplines and sectors, including medicine. PERICO overcomes current barriers by establishing a strong, multidisciplinary and inter-sectoral training network, developing technologies tailored to solve key questions in organelle biology. The PERICO programme will exploit recent developments in high throughput and genome wide screening technologies, combine these with modern molecular cell biology and systems biology and ultimately translate the data into new leads for drug discovery and therapy. This specific cross-disciplinary training program will educate young scientists to a next level, which is needed to advance this research field for the upcoming decennium and to efficiently translate findings into applications. The training programme will be complemented with a complete set of transferable skills.";3974527,44;3974527,44;H2020-MSCA-ITN-2018;/MSCA-ITN-ETN;RIJKSUNIVERSITEIT GRONINGEN;NL;"LIFEGLIMMER GMBH;THE UNIVERSITY OF EXETER;WEIZMANN INSTITUTE OF SCIENCE;ACADEMISCH ZIEKENHUIS GRONINGEN;ALBERT-LUDWIGS-UNIVERSITAET FREIBURG;RUHR-UNIVERSITAET BOCHUM;KATHOLIEKE UNIVERSITEIT LEUVEN;Academisch Medisch Centrum bij de Universiteit van Amsterdam;LAMBERT INSTRUMENTS BV";"DE;UK;IL;NL;BE";;1;0;0;1;0;0 218245;823978;STOP;SIGNED;H2020-EU.1.3.3.;MSCA-RISE-2018;H2020;STop Obesity Platform;2019-03-01;2023-02-28;;The STOP project will bring together an interdisciplinary and intersectoral group of subject matter experts from industry and academia under one umbrella, to address the health societal challenge of obesity with the specific objectives of mitigating the enormous and growing Health Care costs of obesity and related health issues (like heart disease, diabetes, arthritis, liver disease, gallstones, cancer, dementia) that burden European citizens. The STOP project will address this need through the foundation of an innovative platform to support persons with obesity with a better nutrition under supervision of healthcare professionals. Therefore, the STOP platform will capture various PwO data from different kind of smart sensor streams and chatbot technology, manage and enrich available data with existing knowledge bases and fuse these by machine learned driven data fusion approaches for sophisticated AI data analysis. Essentially, this gathered and analysed data and knowledge is accessible and usable for Health Care professionals amongst others as input for a gamification approach to teach PwO healthier nutrition. In the STOP validation an app that establishes an analogy to Dorian Gray mirror, teaching healthier nutrition.;929200;929200;H2020-MSCA-RISE-2018;/MSCA-RISE;FTK FORSCHUNGSINSTITUT FUR TELEKOMMUNIKATION UND KOOPERATION EV;DE;"OKKAM SRL;INCONTEC GMBH;UNIVERSITA DEGLI STUDI DI NAPOLI FEDERICO II;CORK INSTITUTE OF TECHNOLOGY;GLOBIT-GLOBALE INFORMATIONSTECHNIKGMBH;UNIVERSITY OF ULSTER";"IT;DE;IE;UK";;1;0;0;1;0;0 218061;813904;TerraNova;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2018;H2020;The European Landscape Learning Initiative: Past and Future Environments and EnergyRegimes shaping Policy Tools;2019-04-01;2023-03-31;;"Terra Nova: The New Learning Initiative between Humanities and Science: Mapping Past Environments and Energy Regimes, Rethinking Human Environment Interaction and Designing Land Management Tools for Policy. This project aims at improving our diachronic long term understanding of landscape histories and land use strategies in Europe in the Holocene and Anthropocene. Previously identified socio-cultural transitions and the effects of natural forcings will be critically assessed in a new intellectual interdisciplinary arena created by the Terra Nova project. Regional and continental syntheses will be used to anchor a new generation of landscape and climate change models which include the effects of past human actions and generate scenarios for landscape management and rewilding. Ultimately this project will contribute to identifying major previous shifts in resource use and energy regimes and provide options for the future transition to a low carbon society. Can we identify a balance between natural and cultural landscapes changing over space and time? Can we establish a natural reference for ‘European landscapes’ to evaluate current and future measures of landscape planning, ecosystem restoration and rewilding? Or are both systems so intertwined that the separation of the human from the natural is complex and scale and time dependant? Some researchers mark the industrial revolution as the start of the Anthropocene, others argue that long ago humans in Europe had a larger influence than natural processes upon the landscape. Notwithstanding these differences, there is consensus that the intensity of management and impacts of land management on natural systems today is unprecedented. This leads on to consideration of themes of sustainability and societal impact upon landscapes in the 21st century. From this perspective knowledge of past energy regimes and landscape interactions are essential components in understanding the present transition to a low carbon society.";4090952,52;4090952,52;H2020-MSCA-ITN-2018;/MSCA-ITN-ETN;STICHTING VU;NL;"AARHUS UNIVERSITET;UNIVERSITEIT LEIDEN;MARTIN-LUTHER-UNIVERSITAET HALLE-WITTENBERG;UNIVERSITETET I SOROST-NORGE;UPPSALA UNIVERSITET;STICHTING REWILDING EUROPE;UICN, BUREAU DE REPRESENTATION AUPRES DE L'UNION EUROPEENNE AISBL;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS";"DK;NL;DE;NO;SE;BE;FR";;1;0;0;1;0;0 197870;648377;ReactiveFronts;SIGNED;H2020-EU.1.1.;ERC-CoG-2014;H2020;Mixing interfaces as reactive hotspots of porous media flows: theoretical upscaling, experimental imaging and field scale validation;2015-10-01;2020-09-30;;"In porous media, mixing interfaces such as contaminant plume fringes or boundaries between water bodies create highly reactive localized hotspots of chemical and microbiological activity, whether in engineered or natural systems. These reactive fronts are characterized by high concentration gradients, complex flow dynamics, variable water saturation, fluctuating redox conditions and multifunctional biological communities. The spatial and temporal variability of velocity gradients is expected to elongate mixing interfaces and steepen concentration gradients, thus strongly affecting biochemical reactivity. However, a major issue with porous media flows is that these essential micro-scale interactions are inaccessible to direct observation. Furthermore, the lack of a validated upscaling framework from fluid- to system-scale represents a major barrier to the application of reactive transport models to natural or industrial problems. The ambition of the ReactiveFronts project is to address this knowledge gap by setting up a high level interdisciplinary team that will provide a new theoretical understanding and novel experimental imaging capacities for micro-scale interactions between flow, mixing and reactions and their impact on reactive front kinetics at the system scale. ReactiveFronts will develop an original approach to this long-standing problem; combining theoretical, laboratory and field experimental methods.The focus on reactive interface dynamics, which represents a paradigm shift for reactive transport modelling in porous media, will require the development of original theoretical approaches (WP1) and novel microfluidic experiments (WP2). This will form a strong basis for the study of complex features at increasing spatial scales, including the coupling between fluid dynamics and biological activity (WP4), the impact of 3D flow topologies and chaotic mixing on effective reaction kinetics (WP3), and the field scale assessment of these interactions (WP5).";1998747;1998747;ERC-2014-CoG;/ERC-COG;UNIVERSITE DE RENNES I;FR;;;;1;0;0;1;0;0 198212;666952;EcOILogy;SIGNED;H2020-EU.1.1.;ERC-ADG-2014;H2020;Microbial life in oil;2015-09-01;2020-08-31;;"Microbial biodegradation is a key factor influencing the quality of oil and, according to current concepts, takes place mostly at the continuous oil-water transition zone in oil reservoirs. I recently discovered microorganisms in minuscule water droplets (1-3 µl) entrapped in oil from a natural oil seep. In EcOILogy, I propose that biodegradation of oil resources takes place in such minuscule water droplets dispersed in the oil phase which is a shift of paradigm and a new conceptional view for environmental science, -life in oil-. EcOILogy aims to explore this new world investigating the generic principles of life in oil. I will study if such droplets are a common phenomenon in degraded oil resources and how significant the respective degradation activities are. To this end, I will develop reverse stable isotope labelling as a novel method for quantifying minute microbial activities (WP 1). The droplets provide a unique test system of micro-ecosystem, all experiencing identical boundary conditions in the oil with no dispersion of microorganisms between the isolated droplets. I will study how microbial communities for oil degradation assemble in the droplets allowing for unprecedented testing of ecological theory including a new bimodal hypothesis of community assembly. To tackle the big challenge of metabolic traits in systems ecology, I will make use of metagenomics, single cell sequencing, and high resolution metabolomics to assess the functions in single water droplets (WP 2). Finally, I will study how microorganisms adapt to this extreme environment under saturated hydrocarbon concentrations by isolation and comparative genome analysis of strains and study the role of different organisms in the droplets by Raman-CLSM (WP 3). Thus, EcOilogy opens new horizons for microbial degradation of our most important energy resources with far-reaching implications for fundamental, interdisciplinary understanding of ecological processes, bioremediation, and oil exploration";2549250;2549250;ERC-2014-ADG;/ERC-ADG;UNIVERSITAET DUISBURG-ESSEN;DE;;;;1;0;0;1;0;0 198442;647272;Perspectival Realism;SIGNED;H2020-EU.1.1.;ERC-CoG-2014;H2020;Perspectival Realism. Science, Knowledge, and Truth from a Human Vantage Point;2016-01-01;2020-12-31;;"This project develops a novel view in philosophy of science called perspectival realism, via a three-pronged highly interdisciplinary approach, which combines the philosophy of science, with scientific practice, the history of science and the history of philosophy. Scientific perspectivism has recently attracted a great deal of attention for its ability to account for the perspectival nature of modelling, pervasive in the physical sciences, the life sciences, and the social sciences. Can scientific knowledge be perspectival, and at the same time, true? Can perspectivism be made compatible with realism? Four goals guide and structure the project: (1) To offer a systematic investigation of how contemporary physicists deal with the perspectival nature of modelling, either by exploring innovative non-perspectival methods (in particle physics), or by devising ways of integrating different data sets and optmising their use for heuristic purposes (in observational cosmology). (2) To examine, via salient historical case studies, to what extent scientific controversies and disagreement among scientists can be traced back to perspectival modelling, including measurement and experimental techniques. (3) To re-assess the historical origins of perspectivism as a distinctive mode of scientific inquiry back to the Enlightenment, and in particular to Kant's 'Copernican Revolution'. (4) To critically elaborate a metaphysics for perspectival realism that can ultimately answer the overarching question: 'Can perspectivism be made compatible with realism'? The outcome is a scientifically and historically informed philosophical position, with the groundbreaking potential of advancing traditional debates about pluralism, unification, and realism in scientific research. The project pursues these goals via an innovative methodology, in five sub-projects, bringing together physicists, historians of science and of philosophy, and philosophers of science, in an unprecedented way.";1606155;1606155;ERC-2014-CoG;/ERC-COG;THE UNIVERSITY OF EDINBURGH;UK;;;;1;0;0;1;0;0 197442;664771;TRUST;SIGNED;H2020-EU.5.f.;GARRI-6-2014;H2020;Creating and enhancing TRUSTworthy, responsible and equitable partnerships in international research;2015-10-01;2018-12-31;;"The goal of the TRUST Project is to catalyse a global collaborative effort to improve adherence to high ethical standards around the world. Achieving equity in international research is one of the pressing concerns of the 21st century. Many international groups and organisations are working on governance frameworks and standards to guide research activities after progressive globalization. However, their efforts are disparate and lacking a guiding vision. In an interdisciplinary collaboration between multi-level ethics bodies, policy advisors, civil society organisations, funding organisations, industry and academic scholars from a range of disciplines, this project combines long-standing, highly respected efforts to build international governance structures with new exciting network opportunities between Europe, India, Sub-Saharan Africa, China and Russia. TRUST will open up new horizons in improving adherence to high ethical standards in research globally. The project's strategic output are three sets of tools based on participatory engagement covering all continents: (1) a global code of conduct for funders, (2) a fair research contracting on-line tool and (3) a compliance and ethics follow-up tool, which takes limited resources into account.";2651258,75;2141173,25;H2020-GARRI-2014-1;/CSA;UNIVERSITY OF CENTRAL LANCASHIRE;UK;"ACTION CONTRE LA FAIM;INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE;SIGNOSIS SPRL;UNITED NATIONS EDUCATIONAL, SCIENTIFIC AND CULTURAL ORGANIZATION -UNESCO;PARTNERS FOR HEALTH AND DEVELOPMENT IN AFRICA (PHDA);UNIVERSITY OF CAPE TOWN;EUROPEAN & DEVELOPING COUNTRIES CLINICAL TRIALS PARTNERSHIP;UNIVERSITY OF THE WITWATERSRAND JOHANNESBURG;FORUM FOR ETHICS REVIEW COMMITTEESIN INDIA;STIFTUNG GLOBALE WERTE ALLIANZ;THE SOUTH AFRICAN SAN INSTITUTE TRUST;COUNCIL ON HEALTH RESEARCH FOR DEVELOPMENT ASSOCIATION";"FR;BE;KE;ZA;NL;IN;CH";;1;0;0;1;0;0 214857;787011;SPEAR;SIGNED;H2020-EU.3.7.4.;DS-07-2017;H2020;SPEAR: Secure and PrivatE smArt gRid;2018-05-01;2021-04-30;;Over the last decade, cyber-attacks have become increasingly sophisticated, stealthy, targeted and multi-faceted which may leverage zero-day exploits and highly creative interdisciplinary attack methods. As our society is becoming increasingly dependent on Critical INfrastructures (CIN), new technologies are needed to increase our detection and response capabilities. Detecting and responding to such attacks by a highly motivated, skilled and well-funded attacker has however been proven highly challenging. One of the most vulnerable and high-impact CIN is the Smart Grid. Smart Grid is considered as the next-generation power system, which promises self-healing, resilience, sustainability and efficiency to the energy Critical Infrastructures (CIN). However, securing smart grids against cyber-attacks is of vital importance for National Security and Public Safety, since the collapse of an energy production utility may cause human lives, millions of euros, denial of a very important and common good such as energy and days or even months of recovering. To this end, the SPEAR proposal aims at a) detecting and responding to cyber-attacks using new technologies and capabilities, b) detecting threat and anomalies timely, c) developing all-in-one security detection solutions, d) leveraging advanced forensics subject to privacy-preserving, e) confronting Advanced Persistent Threat (APT) and targeted attacks in smart grids, f) increasing the resilience of the smart grid innovation, g) alleviating the lack of trust in smart grid operators and h) empowering EU-wide consensus. Within SPEAR, four proof-of-concept Use Cases are planned in order to validate and assess the implemented security and privacy tools.;2965569,14;2965569,14;H2020-DS-SC7-2017;/RIA;PANEPISTIMIO DYTIKIS MAKEDONIAS;EL;"G.E. PUKHOV INSTITUTE FOR MODELINGIN ENERGY ENGINEERING OF THE NATIONAL ACADEMY OF SCIENCES OF UKRAINE;MVETS LENISHTA OOD;SCHNEIDER ELECTRIC FRANCE SAS;ETHNIKO KENTRO EREVNAS KAI TECHNOLOGIKIS ANAPTYXIS;PUBLIC POWER CORPORATION S.A.;FUNDACION TECNALIA RESEARCH & INNOVATION;EUROPEAN DYNAMICS LUXEMBOURG SA;ENEL IBERIA SRL;SIDROCO HOLDINGS LIMITED;0 INFINITY LIMITED;INCITES CONSULTING SARL;EIGHT BELLS LTD;UNIVERSITY OF SURREY;TECHNICAL UNIVERSITY OF SOFIA;GOTTFRIED WILHELM LEIBNIZ UNIVERSITAET HANNOVER";"UA;BG;FR;EL;ES;LU;CY;UK;DE";;1;0;0;1;0;0 198819;687847;COMRADES;SIGNED;H2020-EU.2.1.1.;ICT-10-2015;H2020;Collective Platform for Community Resilience and Social Innovation during Crises;2016-01-01;2018-12-31;;Response to crisis often reveals organisational and technological shortcomings, which threaten community recovery and sustainable. Even though some technological solutions exist, challenges of communication, interoperability, and data analytics remain. The deployment and use of technologies, and the social structures in which they are adopted, are interdependent. Hence it is imperative to develop human-centred technologies that take into account actual real world practices of affected populations and responders. The rise of social media as an information channel during crisis has become key to community resilience and response. However, existing crisis awareness applications, such as Ushahidi, while vital for information gathering, often struggle to address the challenges of real-time social data analysis and aggregation of crisis micro-events, and filtering of unverified content and reporters. This project will build an intelligent collective resilience platform to help communities to reconnect, respond, and recover from crisis situations. COMRADES will achieve this through an interdisciplinary, socio-technical approach, which will draw on the latest advances in computational social science, social computing, real-time analytics, text and social media analysis, and Linked Open Data. The platform specifications and design requirements will be derived through participatory design workshops with existing activist, responder, and reporter communities. The open source COMRADES platform will go beyond the now standard data collection, mapping, and manual analysis functions provided by the underpinning, widely used Ushahidi crisis mapping tool, to include new intelligent algorithms aimed at helping communities, citizens, and humanitarian services with analysing, verifying, monitoring, and responding to emergency events. COMRADES platform will be deployed and evaluated with multiple, local and distributed, communities, using collective multilingual crisis information.;1999021,25;1999021,25;H2020-ICT-2015;/RIA;THE OPEN UNIVERSITY;UK;"THE UNIVERSITY OF SHEFFIELD;UNIVERSITETET I AGDER;I-HUB LIMITED;TECHNISCHE UNIVERSITEIT DELFT;Government To You";"UK;NO;KE;NL;BE";;1;0;0;1;0;0 205549;722606;TEMPERA;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2016;H2020;Teaching Emerging Methods in Palaeoproteomics for the European Research Area;2017-03-01;2021-02-28;;"TEMPERA will provide international, intersectoral and interdisciplinary state-of-the-art doctoral training to prepare the next generation of specialists in mass spectrometry-based ancient protein residues analysis for biomolecular diagnostics and conservation of cultural heritage material. Due to their chemical and mechanical properties, proteins have always represented the category of biomolecules most extensively exploited by humans to satisfy basic needs, including: nutrition, clothing, sheltering and transportation. However presently there are very few specialists that have been trained to analyse ancient proteins, in stark contrast to the study of ancient DNA. The growing demand of information provided by mass spectrometry-based ancient protein sequencing will require highly specialised profiles with a multidisciplinary background in analytical chemistry, engineering, molecular biology, archaeology and art restoration. Within the TEMPERA network, a team of talented young scientists from both experimental sciences and cultural heritage conservation disciplines will be created and prepared to become a group of highly qualified specialists. The TEMPERA network aims at: (i) forming, through research-based training, the professional profiles behind tomorrow’s state-of-the-art analysis of ancient proteins from cultural heritage materials, (ii) consolidating existing constructive interaction across disciplines to focus different expertise and backgrounds into the common aim of safeguarding and enhancing European cultural heritage, (iii) stimulating, through the right set of specific research-related and transferable skills, the development of application-oriented mind set for direct or indirect exploitation of TEMPERA R&D activities. As a key TEMPERA feature, the unique contribution provided by each participating institution will be integrated in a strong partnership to achieve valuable complementary research-specific and widely transferrable professional competence.";2186974,8;2186974,8;H2020-MSCA-ITN-2016;/MSCA-ITN-ETN;KOBENHAVNS UNIVERSITET;DK;"UNIVERSITA DEGLI STUDI DI NAPOLI FEDERICO II;UNIVERSITY OF YORK;DEVRO PLC;UNIVERSITE DE LILLE;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;UNIVERSITE DES SCIENCES ET TECHNOLOGIES DE LILLE - LILLE I";"IT;UK;FR;DE";;1;0;0;1;0;0 219180;823939;GreenX4Drug;SIGNED;H2020-EU.1.3.3.;MSCA-RISE-2018;H2020;Green Enantioselective Halogenation for Drug Discovery and Manufacture;2019-04-01;2023-03-31;;"The aim of this project is to bring together subject matter experts from the academic and non-academic sectors to develop and exemplify the use of new catalysts and new green reactions to manufacture important halogenated compounds that could be used in drug discovery and drug production. In order to achieve this objective the proposal brings together 3 partners with complementary skills: University of Naples (UNINA): expertise in medicinal chemistry and drug discovery. KelAda Pharmachem: expertise in green chemistry, chemical batch process development and scale-up. UCO: expertise in process engineering of continuous flow processes. We have broken this proposal into the following separate technical Work Packages: WP1: Preparation of new catalysts for efficient desymmetrization [WP Leader: UNINA]. WP2: Development of enantiospecific halogenation including Fluorination. [WP Leader: Kelada Pharmachem]. WP3 Drug Candidate, library creation & in vitro testing. [WP Leader: Kelada Pharmachem] WP4 Development of flow variant and scale-up.[WP Leader: UCO} The above WP's will be undertaken via a series of interlinked secondment of researchers between the consortium partners and will be complemented by a series of training and other initiatives to facilitate interdisciplinary and inter-sectoral knowledge sharing and exchange.";607200;607200;H2020-MSCA-RISE-2018;/MSCA-RISE;UNIVERSITA DEGLI STUDI DI NAPOLI FEDERICO II;IT;"KELADA PHARMACHEM LIMITED;UNIVERSIDAD DE CORDOBA";"IE;ES";;1;0;0;1;0;0 212501;780832;INLINETEST;SIGNED;H2020-EU.2.1.1.;ICT-31-2017;H2020;In-line quality inspection system for smart production of micro and nanoelectronic components;2018-01-01;2020-12-31;;"Future micro/nano-electronics components production will need to be smart and provide instantaneous information on all items for complete traceability. This is necessary as enormous quality requirements have to be met by industrial manufacturers to be competitive in this growing multi-billion market. The crucial ingredient for this development is the availability of rapid in-line-capable inspection systems to unequivocally detect production flaws and defects in the component. To respond to these challenges, the fast, contactless and non-destructive full-field thermometric methods of Pulse-Infrared Thermography (PIRT) and Thermoreflectance (TR) are exploited for the first time to enable 100% in-line inspection in the production line. INLINETEST’s objective is to take up these challenges in design, realization, deployment and test: Existing prototypes for both methods will be adapted and upgraded to the challenges of inline testing, enhanced by hard- and software innovations. For validation under real-life conditions, both failure analytical method’s hard- and software will be customized and integrated into two production lines and demonstrated on two encapsulated power multi-chip module (MCM) components and one in-line production tool at the project partners, covering crucial aspects of the avionics, telecom and automotive sector. The consortium, composed of five partners from industry, SME and academia from 3 European countries, pools excellence and interdisciplinary skills to address these tasks. We are convinced that INLINETEST will enable the first in-line-capable inspection system for 100% monitoring of micro/nano-electronics production based on the thermographic methods of IR and TR, meet the aggressive precision and efficiency targets presented in the proposal and hence boost productivity and radiate out to other lines and products where non-contact failure analysis below surfaces of various emissivity is needed. Thus, the route for smart production is pre";1762631,25;1332916,88;H2020-ICT-2017-1;/IA;BERLINER NANOTEST UND DESIGN GMBH;DE;"ADVANCED PACKAGING CENTER BV;BOSCHMAN TECHNOLOGIES BV;TECHNISCHE UNIVERSITAET CHEMNITZ;THALES SA";"NL;DE;FR";;1;0;0;1;0;0 209022;750866;HOU-DUAL;TERMINATED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;HOUSING DUALIZATION: DIVIDED HOUSING CAREERS AND THE FINANCIALIZATION OF HOUSING MARKETS;2017-05-23;2020-04-21;;Recent years have seen a transformation of housing careers. Significant homeownership declines among young adults is evident across Europe, with growing shares in rental or staying on in the parental home. These are not merely symptoms of a temporary recession, but are outcomes of fundamental changes in labour and housing markets alongside shifting state roles. Even in so-called ‘homeowner societies,’ a future of mass homeownership appears unlikely. Rather, we see increasingly divided sectors where insiders have seen sizable asset growth contrasted with significant shares shut out from the housing market. Globally, ‘financialization’ processes have been at forefront of housing market transformation. Financialization describes real forces that have progressively changed the nature of housing, through its integration with global capital flows, neoliberal re/deregulation and increasing commodification: changes that may exacerbate the translation of labour to housing divides. All this, in an era where labour inequalities have increased and housing assets have grown in importance in the face of welfare cutbacks. Given varied homeownership entry, diverging market outcomes, and intergenerational transmission, housing is clearly central to structuring inequalities. Forces of financialization have only amplified the importance of housing towards socio-economic divides. The proposal develops a theoretical and empirical understanding of how European housing is increasingly structured by insider-outsider dynamics - or housing dualization - within contexts of labour inequality and financialization. The quantitative approach is both multi-scalar and interdisciplinary. First addressing macro-level housing divides across national settings, followed by multi-level analyses into individual outcomes structured by differing national and regional contexts. The research builds on distinct literatures across: labour market dualization, comparative housing studies, and financialization.;160800;160800;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;KATHOLIEKE UNIVERSITEIT LEUVEN;BE;;;;1;0;0;1;0;0 206251;732513;HEPHAESTUS;SIGNED;H2020-EU.2.1.1.;ICT-25-2016-2017;H2020;Highly automatEd PHysical Achievements and PerformancES using cable roboTs Unique Systems;2017-01-01;2020-06-30;;The proposal addresses novel concepts for introducing Robotics and Autonomous Systems in the Construction Sector where, at this moment, the presence is minor. Specifically, the Hephaestus project focuses on highly risked and critical construction tasks such as prefab wall installation. In that sense, the Hephaestus has been conceived as a solution for accomplishing multiple tasks on vertical or inclined planes of the built and outdoor environment. For that purpose, the Hephaestus is mainly based on a cable-driven robot and a modular end effector kit. This modular kit can host several tools and devices and therefore we can say it is multifunctional. Among the functionalities, the research project will achieve tasks such as 3D laser scanning of the building structure and the posterior installation of the prefab wall. But we can foresee some other performances such as the cleaning and maintenance of the curtain wall, repair of cracks and painting. The apparatus of the Hephaestus is lean, compatible with other handling systems, highly versatile and its reachability is very broad. Moreover, the controlling system would offer and easy and fast calibration. For achieving this goal, matrix based design methods will be used. It basically consists on decomposing a complex solution, such as the Hephaestus, into interdependent subsystems that can be feasible to solve. Certainly, the integration and adaptation of several technologies into the Hephaestus will be carried out with a systematic approach that will facilitate the election, adjustment and development of suitable tools. This proposal envisages continuous techno-economical assessment, which includes several tests in real conditions where prototypes of the cable-robot and the modular end-effector kit will be demonstrated. As an output of the research, the well balanced consortium and its interdisciplinary expertise will offer a realistic solution to cover primordial needs of the Built Environment and Construction sector.;4669960;3984542,5;H2020-ICT-2016-1;/IA;FUNDACION TECNALIA RESEARCH & INNOVATION;ES;"FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.;TECHNISCHE UNIVERSITAET MUENCHEN;CEMVI CATENA ELEVACION MANUTENCION VICINAY SA;FOCCHI SPA;R2M SOLUTION LTD;NLINK AS;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;ACCIONA CONSTRUCCION SA";"DE;ES;IT;UK;NO;FR";;1;0;0;1;0;0 204804;693599;FLOOD-serv;SIGNED;H2020-EU.3.6.;INSO-1-2015;H2020;Public FLOOD Emergency and Awareness SERVice;2016-08-01;2019-07-31;;"Floods are an increasingly acute problem. Floods endanger lives and cause human tragedy as well as heavy economic losses. In addition to economic and social damage, floods can have severe environmental consequences, for example when installations holding large quantities of toxic chemicals are inundated or wetland areas destroyed. Intense precipitation has become more frequent and more intense, growing manmade pressure has increased the magnitude of floods that result from any level of precipitation, and flawed decisions about the location of human infrastructure have increased the flood loss potential. Flooding cannot be wholly prevented. Flood risk increases with ongoing climate change. Risk reduction in large international basins can only be achieved through transnational, interdisciplinary and stakeholder oriented approaches within the framework of a joint transnational research project. The overall objective of FLOOD-serv is to develop and to provide a pro-active and personalised citizen-centric public service application that will enhance the involvement of the citizen and will harness the collaborative power of ICT networks (networks of people, of knowledge, of sensors) to raise awareness on flood risks and to enable collective risk mitigation solutions and response actions. Other general objectives are: 1. Empowering local communities to directly participate in the design of emergency services dealing with floods mitigation actions. 2. Harness the power of new technologies, such as social media, and mobile technologies to increase the efficiency of public administrations in raising public awareness and education regarding floods risks, effects and impact. 3. Encourage the development and implementation of long-term, cost-effective and environmentally sound mitigation actions related to floods though an ICT-enabled cooperation and collaboration of all stakeholders: government, private sector, NGOs and other civil society organizations as well as citizens.";3226375;2528630,63;H2020-INSO-2015-CNECT;/IA;SIVECO ROMANIA SA;RO;"COMUNE DI GENOVA;INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE DELTA DUNARII;EXDWARF CONSULTING SRO;BRATISLAVSKY SAMOSPRAVNY KRAJ;INSTITUTIA PREFECTULUI JUDETUL TULCEA;MUNICIPIO DE VILA NOVA DE FAMALICAO;AYUNTAMIENTO DE BILBAO;A.N.O. SISTEMAS DE INFORMATICA E SERVICOS LDA;Government To You;ANSWARETECH SL;CELLENT GMBH";"IT;RO;SK;PT;ES;BE;AT";;1;0;0;1;0;0 201648;709122;IMPACT;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Physics of Impact Cratering Collapse;2016-12-15;2018-12-14;;"This research project will study the formation of large meteorite impact craters, characterized by central peaks or rings, flat floors and terraced walls. The complex morphology results from the gravity driven collapse of a much deeper and narrower transient cavity. Standard material models fail to explain such a collapse and specific temporary weakening mechanisms have been proposed. The most successful approach, the Acoustic Fluidization (AF) model, relies on the temporary softening of heavily fractured target rocks by means of an acoustic field in the wake of an expanding shock wave originated upon impact. The project aims to (i) constrain the mechanics of large crater collapse, (ii) constrain AF parameters and enhance AF implementation into simulation software (iSALE), (iii) test the revised AF model with planetary case studies. These objectives will be achieved through a multidisciplinary approach: (1) Small-scale impact experiments will use a target of granular material, which will be acoustically fluidized by an external source to mimic the fluid-like rheology of planetary targets during collapse; (2) Numerical models of complex crater formation, which require the AF parameters to be constrained, will be calibrated and validated against experiments and up-scaled to dimensions of natural craters. The originality lies in combining the systematic laboratory experiments with numerical simulations to improve a widely used AF model. The fulfilment of the project will be ensured by the host and partner institutes, and the planned training activities (laboratory and modelling techniques). The results will be disseminated to the scientific community through peer-reviewed papers and conference contributions. The project will foster excellence in Europe by establishing a network of collaborations that will promote high-quality research, inspire the next generation of planetary scientists, and encourage research in interdisciplinary fields like Solar System exploration.";159460,8;159460,8;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;MUSEUM FUR NATURKUNDE - LEIBNIZ-INSTITUT FUR EVOLUTIONS- UND BIODIVERSITATSFORSCHUNG AN DER HUMBOLDT-UNIVERSITAT ZU BERLIN;DE;;;;1;0;0;1;0;0 201005;702019;IGATO;CLOSED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;The introduction of the glaze in al-Andalus: technological waves and Oriental influences;2016-09-15;2018-09-14;;"The project is designed to develop a much-needed approach to the study of glaze ware production in al-Andalus (Spain and Portugal) during the Middle Ages (9th-13th centuries). The introduction of the glaze in the Iberian Peninsula was a complex and long process involving several waves of technology transfer arriving from the Eastern to the Western Mediterranean basin, in different political periods. From the archaeometric analytical point of view, both petrographic and chemical, this proposal aims to enrich knowledge about glazed ceramic technology in the Western Islamic world: identification of the Mediterranean access routes, localization of Andalusi workshops and their spread and distribution through the Iberian Peninsula. The microstructure and composition of the glazes, the raw materials and the colorants and decorative techniques used, as well as, the introduction of Eastern patterns, will provide some hints. Finally, the glazed ware as an element of political cohesion and, of course, as a sign of religious identity in al-Andalus will also be assessed. To carry out the project successfully a methodology and a work plan with different phases, milestones and deliverables will be developed. The key project is based on its interdisciplinary, applying archaeometric techniques to analysis of material culture, in this case, the glaze technology, and hence establishing links between Social sciences and Science, with new approaches to the interpretation of the history and archaeology of al-Andalus.";170121,6;170121,6;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;UNIVERSITAT POLITECNICA DE CATALUNYA;ES;;;;1;0;0;1;0;0 215020;790736;hetero-switch;TERMINATED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Smart heterostructures based on 2D materials and switching magnetic molecules.;2019-03-25;2021-03-24;;"Future smart multi-functional logic devices might combine switchable molecules and two-dimensional layered materials (2D-LMs). Spin crossover (SCO) compounds are a paradigmatic example of molecular switches including cooperative spin-transitions. One of their hallmarks is the huge concomitant strain arising upon SCO up to 13 % responding to numerous external stimuli even above room temperature. Besides, hundreds of 2D-LMs were discovered after the isolation of thin graphene layer(s) from graphite. Such a plethora of diverse atomic layers with distinct properties opened the door to design novel van der Waals heterostructures (vdWHs) with artificially engineered functionalities. Introducing external interactions or strain can give the ability to tune optical band gaps and electrical properties of 2DLMs-vdWHs. Still in its infancy, this strategy promises new properties and exciting physics seeking thereafter unprecedented device performance and applications. This interdisciplinary project intends at pioneering design, preparation and investigations of the electrical transport and magnetotransport properties of SCO/2D-LMs-vdWHs. Signs of the coexistence, or even synergy, of several physical properties of interest will be painstakingly researched. This quest encompasses manifestations of magnetism, conductivity, and superconductivity influenced by thermal- and light-induced SCO cooperative spin-transitions, pursuing innovative 2D nanoelectronics, energy applications and flexible sensors.";170121,6;170121,6;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;UNIVERSITAT DE VALENCIA;ES;;;;1;0;0;1;0;0 215763;799873;ULTRACONTROL;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Ultra-low cost orbit transfer and orbit control for future libration point missions;2019-09-01;2021-08-31;;"The key objective of this ambitious and adventurous program of research is to develop an entirely new method of spacecraft orbit transfer and orbit control using solar sails, driven only by solar radiation pressure. The new method will enable ultra-low cost libration point missions, with numerous applications in space science, Earth observation and telecommunications. To achieve this goal, orbit transfer and orbit control for such libration point missions will be investigated using modern dynamical system theory with solar radiation pressure. This provides a key advantage over conventional thrusters, since a solar sail does not require propellant, thus reducing spacecraft mass and launch costs while significantly lengthening mission duration. Through this programme of research, practical control strategies will be evaluated and engineering requirements on solar sail size and performance assessed. The programme of research will be supported by the interdisciplinary Space Glasgow Research Cluster and the host’s extensive network of international collaborators on solar sailing (ESA, NASA, NOAA). The host supervisor is the acknowledged international leader in the rapidly developing field of solar sailing. The therefore project offers a golden opportunity to link the Experienced Research’s prior work on real-world solar sail mission operations at the Japanese Space Agency (JAXA) with the host’s extensive expertise in solar sail orbital dynamics.";195454,8;195454,8;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;UNIVERSITY OF GLASGOW;UK;;;;1;0;0;1;0;0 214862;787061;ANITA;SIGNED;"H2020-EU.3.7.6.;H2020-EU.3.7.1.";SEC-12-FCT-2016-2017;H2020;Advanced tools for fighting oNline Illegal TrAfficking;2018-05-01;2021-04-30;;"ANITA will design and develop a novel knowledge-based user-centred investigation system for analysing heterogeneous (text, audio, video, image) online (Surface Web, Deep Web, DarkNet) and offline content for fighting illegal trafficking of drugs, counterfeit medicines, NPS and firearms. ANITA will combine a) innovative data source analysis of crypto-currency network and transactions and blockchain technologies; b) advanced Big Data analytics tools for automatic analysis of the vast amounts of multimodal content of the identified sources; c) sophisticated methodologies for capturing, modelling and inferring knowledge in human understandable forms (e.g. expressive ontologies), extracting also relevant and new knowledge from neural networks and formally storing it in the form of ontologies; d) development of an adaptive, cognitive user modelling framework that will capture, analyse, interpret, mimic and integrate key human cognitive and information processing functions for: i) incarnating the incorporation of human perception/cognition principles in the system processing pipelines (i.e. integrating the investigators ‘in-the-loop’ of the overall analysis process) and ii) facilitate the transfer of domain knowledge from the expert users to the novice ones; e) domain-related and user-oriented intelligence applications, which will enable users to identify patterns for spatial, temporal and causal correlations among illegal trafficking events, entities and activities and to support decision-making processes for countermeasures to undertake. All the above functionalities will be coupled and reinforced by an in-depth interdisciplinary analysis of the online illegal trafficking phenomenon (including the study of reaction strategies and countermeasures) and a thorough analysis of the online resources with respect to social, ethical, legal and privacy issues of concern. The proposed system capabilities will be demonstrated in multiple relevant operational environments.";4999580;4999580;H2020-SEC-2016-2017-2;/RIA;ENGINEERING - INGEGNERIA INFORMATICA SPA;IT;"AIT AUSTRIAN INSTITUTE OF TECHNOLOGY GMBH;ETHNIKO KENTRO EREVNAS KAI TECHNOLOGIKIS ANAPTYXIS;RISSC - CENTRO RICERCHE E STUDI SUSICUREZZA E CRIMINALITA ASSOCIAZIONE;KRIMINALISTICKO-POLICIJSKI UNIVERZITET;FUNDACIO INSTITUT DE BIOENGINYERIA DE CATALUNYA;PROVINCIAL POLICE HEADQUARTERS IN GDANSK;ISTITUTO ITALIANO PER LA PRIVACY;VIAS INSTITUTE;SYSTRAN SA;EXPERT SYSTEM SPA;STICHTING DUTCH INSTITUTE FOR TECHNOLOGY, SAFETY & SECURITY;STICHTING KATHOLIEKE UNIVERSITEIT BRABANT;POLITIEZONE BRECHT-MALLE-SCHILDE-ZOERSEL;HOME OFFICE;GLAVNA DIREKTSIA BORBA S ORGANIZIRANATA PRESTUPNOST;THE NATIONAL POLICE OF THE NETHERLANDS";"AT;EL;IT;RS;ES;PL;BE;FR;NL;UK;BG";;1;0;0;1;0;0 215026;791235;SiDMACIB;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Structurally informed Design of Masonry Assemblages Composed of Interlocking Blocks;2018-07-01;2020-06-30;;"Masonry benefits contemporary architecture regarding sustainability and application to free-form construction. A masonry structure can be considered as an assemblage of conventional or interlocking rigid blocks with frictional joints. Although interlocking blocks’ resistance to sliding is higher and their construction is easier when compared to conventional blocks, there is no digital framework to design structurally-sound assemblages composed of interlocking blocks with diverse typologies. Therefore, I intend to develop a digital framework that supports designers in the design of structurally feasible and assemblable masonry assemblages of interlocking blocks. The framework will accomplish the following: -it allows designers to model an assemblage and to analyze its structural feasibility; -for the structurally infeasible model, it will automatically modify the geometry of the interlocking blocks’ connectors, making the model structurally feasible; -during the geometric modification, it will avoid geometries which do not construct the assemblable blocks. To evaluate the structural feasibility, a novel experimental method will equate the frictional resistance of the corrugated face of an interlocking block to that of the flat face of an equivalent conventional block. I also propose an extension of the limit analysis method, in which block resistance to sliding is different in different directions, and plan to use equations from the experimental method. The project is an interdisciplinary research in the fields of architectural, computational and structural design and will train skills helping to establish me as a researcher leading studies on structurally informed architectural design as well as to become an entrepreneurial architect who uses masonry in contemporary architecture. It will also create opportunities for host organizations to collaborate with architectural academia and manufacturing industry in the field of integrated architectural-structural design.";168277,2;168277,2;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;UNIVERSITA DEGLI STUDI DI NAPOLI FEDERICO II;IT;;;;1;0;0;1;0;0 219205;824164;HERMES;SIGNED;H2020-EU.1.2.2.;FETPROACT-01-2018;H2020;Hybrid Enhanced Regenerative Medicine Systems;2019-01-01;2023-12-31;;"Brain disorders are the most invalidating condition, exceeding HIV, cancer and heart ischemia, with significant impact on society and public health. Regenerative medicine is a promising branch of health science that aims at restoring brain function by rebuilding brain tissue. However, repairing the brain is one of the hardest challenges and we are still unable to effectively rebuild brain matter. Epilepsy is particularly challenging due to its dynamic nature caused by the relentless brain damage and aberrant rearrangements of brain rewiring. To overcome the biological uncertainty of canonical regenerative approaches, we propose an innovative solution based on intelligent biohybrids, made by the symbiotic integration of bioengineered brain tissue, neuromorphic microelectronics and artificial intelligence, to effectively drive self-repair of dysfunctional brain circuits and we validate it against animal models of epilepsy. HERMES fosters the emergence of a novel biomedical paradigm, rooted in the use of biohybrid neuronics (neural electronics), which we name enhanced regenerative medicine. To this end, HERMES will promote interdisciplinary cross-fertilization within and outside the consortium; it will extend the concepts of enhanced brain regeneration to philosophy, ethics, policy and society to foster the emergence of a new innovation eco-system. Intelligent biohybrids will represent a major breakthrough to advance brain repair research beyond regenerative medicine and neurotechnology alone; it will bring new knowledge in neurobiology, cognitive neuroscience and philosophy, and new neuromorphic technology and AI algorithms. HERMES will bring a giant conceptual leap that will shift the concept of biomedical interventions from treating to healing. In turn, it will potentially generate major returns on health care and society at large by bringing previously unimaginable possibilities to defeat disorders that represent today a global major burden of disease.";8429857,5;8429857,5;H2020-FETPROACT-2018-01;/RIA;FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA;IT;"AARHUS UNIVERSITET;UNIVERSITA DEGLI STUDI DI VERONA;STICHTING KATHOLIEKE UNIVERSITEIT;TTY-SAATIO;AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS;TAMPEREEN KORKEAKOULUSAATIO SR;FUNDACION INSTITUTO DE ESTUDIOS DE CIENCIAS DE LA SALUD DE CASTILLA Y LEON;DEN INSTITUTE;POLITECNICO DI MILANO;UNIVERSITY OF GLASGOW;EUROKLEIS S.R.L.;UNIVERSITA DEGLI STUDI DI MODENA E REGGIO EMILIA";"DK;IT;NL;FI;ES;BE;UK";;1;0;0;1;0;0 217947;813483;INFANS;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2018;H2020;INtegrating Functional Assessment measures for Neonatal Safeguard;2019-01-01;2022-12-31;;INFANS will train 15 ESRs with background from basic to clinical sciences in multiple aspects of neonatal brain monitoring. The need for a coordinated research training programme in neonatal brain monitoring arises from i) the severe shortage of clinically viable means to high quality monitor the brain function in infancy, crucial to prevent later life neurological, cognitive and motor impairment and ii) the lack of well-educated PhDs in this field. Through their individual research projects, encompassing technological innovation, industrial development, clinical validation, identification of neonatal healthcare needs, the INFANS ESRs will develop a novel platform for high quality, clinically-viable EEG-NIRS monitoring accessible worldwide. Excellent science, industrial leadership and societal challenge are merged in INFANS: 6 academic and 4 non-academic partner from 6 EU countries, among which leading universities, industries, clinical institutions, share complementary expertise and facilities to provide international, interdisciplinary and intersectoral research training and mobility that will complement local doctoral training. Well-targeted visits and secondments, soft skills and dynamic training activities, an Open Science strategy, extensive involvement of ESRs in the network events organization, extensive contacts with other research, training and industrial European networks, dissemination activities and the award of Double doctoral degrees are further assets of INFANS. The ESRs will learn to transform a scientific/technological challenge into a product of socio-economic relevance, as the INFANS functional neuro-monitoring system will reduce the number of children with neurological, cognitive or motor dysfunctions associated with brain injuries at birth. The INFANS ESRs will become independent researchers with career prospects in both the academic and non-academic sectors, and will advance the EU capacity for innovation in biomedical engineering.;3950394,84;3950394,84;H2020-MSCA-ITN-2018;/MSCA-ITN-ETN;TECHNISCHE UNIVERSITAET ILMENAU;DE;"EEMAGINE MEDICAL IMAGING SOLUTIONSGMBH;HELSINGIN YLIOPISTO;UNIVERSITA DEGLI STUDI GABRIELE D'ANNUNZIO DI CHIETI-PESCARA;UNIVERSITAIR MEDISCH CENTRUM UTRECHT;KVIKNA EHF;ARTINIS MEDICAL SYSTEMS BV;KATHOLIEKE UNIVERSITEIT LEUVEN";"DE;FI;IT;NL;IS;BE";;1;0;0;1;0;0 215723;799370;MUSICIAN;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Music Processing for Cochlear Implants Based on Auditory and Neural Modelling;2019-09-01;2022-08-31;;'Cochlear implants (CIs) have been tremendously successful in restoring speech communication for deaf people. However, the enjoyment of music through CIs is still quite limited. The objective of the proposed project 'MUSIc processing for Cochlear Implants based on Auditory and Neural modelling' (MUSICIAN) is to extract and transmit the most prominent features of music (rhythm, pitch, timbre) such that the listening effort of CI users is reduced and their music appreciation is improved. To this end, we propose to perform fundamental research into measuring and modelling the CI user's music perception and to develop improved processing methods capable of simplifying music signals to their most essential aspects. The project thus addresses the information bottleneck composed of the electrode array and its interface with the auditory nerve and will be help to reduce the perceived distortions of music in CI listeners. Within the proposed programme, two labs with extensive experience in signal processing and audiology, the Institute of Communication Acoustics at Ruhr-Universität Bochum, (beneficiary residing in Bochum, Germany) and the Auditory Engineering Laboratory at McMaster University (partner organisation residing in Hamilton, Canada) will host the experienced researcher Dr. Anil Nagathil who is a pioneer in the development of music processing methods for CIs. The proposed interdisciplinary project will enable Dr. Nagathil to acquire knowledge from several scientific domains and to integrate this expertise into the methods of auditory modelling and music processing. The outcome of this project has substantial commercial impact and the potential to improve the quality of life of hundreds of thousand CI users worldwide.';243352,8;243352,8;H2020-MSCA-IF-2017;/MSCA-IF-GF;RUHR-UNIVERSITAET BOCHUM;DE;;;;1;0;0;1;0;0 211595;765811;DoDyNet;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2017;H2020;Double Dynamics for design of new responsive polymer networks and gels;2017-11-01;2021-10-31;;"Polymeric gels and networks are ubiquitous in daily life (foodstuff, cosmetics) and high-added value applications (tissue engineering, adhesives, coating, drug release, portable batteries, additive manufacturing). They can be either permanent (covalently crosslinked) and resist flow, or physical (reversible) and easy to process while creeping at long times. The grand challenge is to efficiently combine and control within the same material, distinct features of these two classes of networks, such as large mechanical strength, deformability, swelling and self-healing, in order to create multiply responsive materials for new applications. The objective of DoDyNet is to develop a research roadmap that enhances our understanding of the synergistic effects arising by combining distinct dynamic modes within a polymeric network. These ‘Double Dynamics Networks’ (DDNs) are characterized by a multi-scale viscoelastic response that can be tuned via molar mass, fraction of component and dynamics of (transient or exchangeable) bonds. This will enable us to selectively tailor their macroscopic properties at molecular level. Based on this concept, the integrated research program involves (1) novel synthesis of different DDNs; (2) detailed analysis of structure; (3) rheology and dynamics; (4) modeling and simulations; and (5) mechanical properties relevant to applications. The ESRs will benefit from the close inter-connection among these complementary tasks with the goal to obtain criteria for designing and developing new industrial DDN systems and optimizing existing materials. DoDyNet is a highly interdisciplinary and inter-sectorial project, the groups involved are world-leaders in their fields, and the tasks strategically designed to ensure strong synergies. It offers young researchers an extraordinarily diverse training platform with a deep grasp of soft matter and unique exposure to industrial environment, needed to address emerging scientific and technological challenges.";3340690,2;3340690,2;H2020-MSCA-ITN-2017;/MSCA-ITN-ETN;UNIVERSITE CATHOLIQUE DE LOUVAIN;BE;"DSM MATERIALS SCIENCE CENTER BV;JOHANNES GUTENBERG-UNIVERSITAT MAINZ;ECOLE SUPERIEURE DE PHYSIQUE ET DECHIMIE INDUSTRIELLES DE LA VILLE DEPARIS;UNIVERSITA DEGLI STUDI DI NAPOLI FEDERICO II;FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS;DANMARKS TEKNISKE UNIVERSITET;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS";"NL;DE;FR;IT;EL;DK";;1;0;0;1;0;0 221154;855988;SteriWeed;SIGNED;"H2020-EU.3.;H2020-EU.2.3.;H2020-EU.2.1.";EIC-SMEInst-2018-2020;H2020;The first bioherbicide blocking germination of herbicide-resistant weeds;2019-03-01;2019-06-30;;"Weeds cause more than 35 Billion € annual global losses, equivalent to 34% of crop yield. If weeds were uncontrolled, about 50% of the crops would be lost. Therefore, synthetic (chemical) herbicides have been used since the late 1940s. However, herbicide’s use has resulted in weed’s evolution. Hence, the most persistent challenge of modern agriculture is the increasing incidence of weed resistance. Bioherbicides have been introduced as an efficient, yet environmentally-friendly alternative to synthetic herbicides. However, they perform inconsistently, have limited shelf-life, have potential adverse effects for humans and are not economically viable. Therefore, there is an urgent need to develop new technological methods of weed control and management that do not depend on synthetic herbicide use. We are developing SteriWeed, a novel biological herbicide based on treated pollen and designed to target the resistant-weed and not the crop. It is non-toxic, not chemical engineered, easy to apply and cost-effective. Our innovation lies in its simplicity as the SteriWeed production method consists of only two steps: natural pollen harvesting and irradiation. The results are inviable weeds, unable to produce seeds in the next season. Today, our team of 6 employees with interdisciplinary background have reached the proof of concept of our technology for A. palmeri, one of the most threaten weeds in the US, reaching outstanding weed control results. The goal of this project is to expand our technology towards the control of the main resistant weeds threatening the European crops. We estimate that in five years after launching the commercialization phase, SteriWeed will cover over 1.5 million ha across Europe, Israel and USA. We will reach €42 million in cumulative revenues (cumulative profit of €15.5 million – ROI 7.15). We estimate the payback time in beginning of 2023. We plan to hire 11 new professionals, technical experts as well as professionals in business.";71429;50000;H2020-SMEInst-2018-2020-1;/SME-1;WEEDOUT LTD;IL;;;;1;0;0;1;0;0 214962;789596;MYlandOURland;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;How Institutions Shape Culture: Survey and Experimental Evidence from a Large-Scale Land Tenure Reform Implemented as a Randomized Control Trial;2019-09-01;2021-08-31;;This project aims to isolate the causal effects of formal institutions (mainly, laws and regulations) on cultural variables that influence economic development, such as trust, cooperation, social value orientation, competitiveness, thriftiness, and work ethics, in order to better understand how to design institutions that facilitate market exchange. The applicant will conduct surveys and lab-in-the-field experiments to collect data on these cultural variables in several villages in Benin, West Africa, where a major reform consisting in the formalization of property rights over land was implemented in hundreds of rural villages between 2006 and 2011. The effects of this institutional reform on culture will be estimated by comparing data collected in villages affected by the reform with data from villages where no land rights formalization took place. Identification is based on the randomization process characterizing the selection of villages where the reform took place: the project studies the first – and so far unique – case of land tenure reform implemented as a large-scale randomized control-trial. Given the unique identification strategy that overcomes most of the limitations characterizing previous studies, the use of state-of-the-art methodologies, and an interdisciplinary approach investigating the problem through the prism of gender equality, results will determine important advances in the existing knowledge regarding the optimal design of institutions. These outcomes will directly benefit low- and medium-income countries that are implementing land tenure reforms by suggesting ways to improve the design of new institutions. Furthermore, important benefits deriving from this project will be shared also by western societies, since findings will improve the effectiveness of the resources invested in development aids, and since the results will advance existing knowledge regarding the process and consequences of institutional change.;158121,6;158121,6;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;UNIVERSIDAD POMPEU FABRA;ES;;;;1;0;0;1;0;0 214545;795557;EARNEST;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Examining the Agroforestry Landscape Resilience in India to inform Social-Ecological Sustainability in the Tropics;2018-09-01;2020-06-11;;The effective management of human-dominated tropical forest landscapes is crucial in the wake of global environmental change affecting biodiversity, ecosystem functions, and the livelihoods of billions. To ensure success of such ecological management, it is essential that both planning as well as implementation is informed by long-term ecological knowledge rooted in robust scientific inquiries. Examples of science-based ecological management are rare largely due to paucity of high-resolution past ecological modelling studies that are capable of producing tangible analogues and policy-relevant information on a multi-decadal timescale. To bridge this gap in the light of India’s National Agroforestry Policy (NAP) and its wider relevance to other tropical countries, EARNEST harnesses the recent past to provide guidelines for current-future ecological management of human-dominated tropical landscapes. Adopting innovative statistical approaches (e.g. REVEALS modelling, rarefaction and multivariate ordination) well-founded on palaeoecological science, EARNEST examines the resilience of Indian agroforestry landscapes in relation to past landscape burning and climatic transitions and delivers state-of-the-art understanding of the efficacy of fires in forest management and its implications for the efficient implementation of NAP. Under the MSCA flagship, EARNEST develops this policy-relevant Excellent Science in a highly-skilled, interdisciplinary and equitable European environment, offering unprecedented opportunities for the Fellow to acquire the right technical, management and leadership skills through advanced methodological training and international mobility. Enabling transfer of her newly developed knowledge through open-access publications, conferences, public events and benefit-sharing actions in India will add to her competence in devising and leading high-impact and policy-oriented research, increasing her employability in both academic and non-academic sectors.;171022,95;171022,95;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;THE OPEN UNIVERSITY;UK;;;;1;0;0;1;0;0 214137;794301;SPITFIRE;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;SPatial variability and Implications of the Timing of FIsh Responses to the Environment;2018-11-01;2020-10-31;;"Prediction of fish production is hindered by the lack of high-resolved data, and the complexity of the bio-physical systems affecting fish survival. A key factor determining the survival of larval fish is the relationship between predator recruitment and prey-predator overlap (match-mismatch hypothesis, MMH). MMH thus offers a mechanistic explanation for the fluctuations in fish recruitment, i.e. the number of fish entering the fishery. However, little is known about how MMH mechanistically explains population and ecosystem dynamics across species and regions. Therefore, the main goal of SPITFIRE is to quantify the ability of an improved MMH to globally explain fish dynamics, by acknowledging the roles of zooplankton (animal-like drifters, not just phytoplankton, plant-like drifters), space and mismatch. The data needed to achieve SPITFIRE objectives include long-term phytoplankton, zooplankton, fish distributions and their annual mean timings from a specific location (work package 1), and the Atlantic and the Pacific basins (work packages 1 and 2). All components necessary for project success are in-hand both through the collaborative network of experts already established and data resources via participants providing insight into MMH dynamics, fish life-history dynamics, oceanography, and both the Atlantic and the Pacific ecosystems. By comparing predator-prey relationships, SPITFIRE will help answer the major question in fish ecology and management – what determines fish recruitment? – and thus lead to better management of marine resources. The training-through-research, unique set of transferable skills and intellectual, methodological and interdisciplinary training that I will gain from this project are the essential skills I need to become a leading marine scientist. By building a robust research profile, I can ensure that professional independence to build my own lab will be a sound foundation when pursuing research positions and grants, such as ERC Grants.";208400,4;208400,4;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;UNIVERSITETET I OSLO;NO;;;;1;0;0;1;0;0 208801;724411;TreeGraSP;SIGNED;H2020-EU.1.1.;ERC-2016-COG;H2020;Tree rewriting grammars and the syntax-semantics interface:From grammar development to semantic parsing;2017-07-01;2022-06-30;;"The increasing amount of data available in our digital society is both a chance and a challenge for natural language processing. On the one hand, we have better possibilities than ever to extract and process meaning from language data, and recent techniques, in particular deep learning methods, have achieved impressive results. On the other hand, linguistic research has a much broader empirical basis and can aim at rich quantitative models of language. Unfortunately, theory and application interact too little in these areas of meaning extraction and grammar theory. Current semantic processing techniques do not sufficiently capture the complex structure of language while grammatical theory does not sufficiently incorporate data-driven insights about language. TreeGraSP bridges this gap by combining rich linguistic theory with data-driven approaches to large scale statistical grammar induction and to semantic parsing. The novelty of its approach consists in putting semantics at the center of grammar theory, putting an emphasis on multilinguality and typological diversity, and adopting a constructional approach to grammar. TreeGraSP is interdisciplinary and innovative in serveral respects: It contributes to the field of linguistics by a) making theories of grammar explicit, b) providing a grammar implementation tool for typologically working linguists and c) developing means to obtain a quantitative grammar theory. And it contributes to the field of computational semantics by providing a probabilistic theory of meaning construal that can be used for textual entailment and reasoning applications. The challenge lies in the intended transfer between theoretical linguistics and statistical natural language processing.";1995890;1995890;ERC-2016-COG;/ERC-COG;HEINRICH-HEINE-UNIVERSITAET DUESSELDORF;DE;;;;1;0;0;1;0;0 207042;734325;TESTBED;SIGNED;H2020-EU.1.3.3.;MSCA-RISE-2016;H2020;Testing and Evaluating Sophisticated information and communication Technologies for enaBling a smartEr griD;2017-01-01;2019-12-31;;"Smart grid represents a significant new technology of improving the efficiency, reliability, and economics of the production, transmission, and distribution of electricity. It is crucial to exchange and use information for performing smart grid applications. However, in reality the exchange of information over multiple networks is unreliable, leading to unpredictable network Quality-of-Service and thus unreliable smart grid applications. What’s worse, there are massive data, including metering data and measurement data, structured or unstructured, making it challenging to exploit useful information. Hence, there is an urgent need to solve the research problem: how to coordinate multiple networks to reliably transmit data, and then manage ICT system resources to efficiently extract useful information for supporting smart grid applications? TESTBED is a major interdisciplinary project that combines wisdoms in three academic disciplines - Electronics Engineering, Power Engineering and Computing Sciences, to address the aforesaid problem. The main focus is on improving the communication layer interoperability and the efficiency of data analytic. Regarding the communication layer interoperability, this project intends to develop and evaluate function-driven communication frameworks. Moreover, this project will develop and verify new data integration and analytic techniques for enhancing power grid operations. These developed frameworks and methods will be extensively tested and evaluated in 4 well-equipped Laboratories at HWU, EPRI, ICCS, and CAS. They will not only support the SGAM Framework, but also complement and enhance International Standards. Overall, the main objective of this project is to coordinate the action of 5 Universities and 3 enterprises, working in the field of ICT and smart grid from both EU and China, to build and test sophisticated ICT, thereby facilitating the successful implementation of smart grid applications.";882000;598500;H2020-MSCA-RISE-2016;/MSCA-RISE;UNIVERSITY OF DURHAM;UK;"DOTX CONTROL SOLUTIONS BV;HELLENIC TELECOMMUNICATIONS ORGANIZATION S.A. - OTE AE (ORGANISMOS TILEPIKOINONION TIS ELLADOS OTE AE);HERIOT-WATT UNIVERSITY;INSTITUTE OF COMMUNICATION AND COMPUTER SYSTEMS";"NL;EL;UK";;1;0;0;1;0;0 206386;734749;INSPIRED;SIGNED;H2020-EU.1.3.3.;MSCA-RISE-2016;H2020;Targeting IRE1 in disease;2017-01-01;2020-12-31;;"The overarching objective of this Interfere to Suppress or Promote IRE1 (INSPIRED) RISE programme is to drive research and innovation in cell stress and drug development for cancer and neurodegenerative diseases by forming an interdisciplinary and intersectoral network of experts with strong, dynamic and productive interactions. The partners will work together, each bringing their unique expertise, to develop new classes of therapeutics for these common diseases. By fostering a shared culture of research, innovation and collaboration, the participants will accelerate advances in the field of cell stress responses. The staff members who participate in the programme will develop new skills, learn new technologies and be exposed to new environments which will considerably enhance their career opportunities. Advancing drug development in the stress response field has potential translational and commercial opportunities for the participants and will benefit European society as a whole from economic and health perspectives. IRE1 is a stress sensor and signal transducer, activated in response to the accumulation of misfolded proteins in the endoplasmic reticulum (ER). Its activation is part of a process termed the unfolded protein response (UPR) that determines the fate of cells in response to ER stress. The INSPIRED consortium will focus on understanding IRE1 signalling and its role in the stress response in order to target it in specific diseases such as cancers and neurodegenerative disorders where aberrant IRE1 signalling occurs. Research carried out by INSPIRED partners will develop new IRE1 modulators and generate preclinical data to support targeting IRE1 in cancers and neurodegenerative disease.";886500;832500;H2020-MSCA-RISE-2016;/MSCA-RISE;NATIONAL UNIVERSITY OF IRELAND GALWAY;IE;"INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE;METASYSX GMBH;ENIOS APPLICATIONS IDIOTIKI KEFALAIOUCHIKI ETAIREIA";"FR;DE;EL";;1;0;0;1;0;0 201185;703886;CFQMLD;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;A Computational Framework For Quantitative Modeling of Leaf Development in Arabidopsis and Cardamine;2017-01-01;2018-12-31;;"Understanding how form emerges in living organisms is a fundamental challenge for biology. Progress, however, has been confounded by the complex chain of interactions underlying the organization of macroscopic forms from molecular processes. Consequently, insights into the manner in which individual genes contribute to the development of form have been elusive; even in well-studied model organisms. In this context, leaves provide a striking example of the self-organization of form – displaying remarkable diversity within and between species. Now, exploiting the close relation between simple leafed A. thaliana and compound leafed C. hirsuta, the Tsiantis lab has identified the key genetic factors underlying their distinct leaf shapes. This opens the door to a detailed understanding of the developmental factors sculpting leaf form. Due to the complexity of leaf development, however, a mechanistic understanding of these factors requires computational models, informed by detailed quantitative measurements of growth and gene expression. Such models permit the systematic interrogation of the interactions linking genetic regulation, cell division and tissue growth to final form. This action proposes to develop such a computational framework. When combined with experimental efforts, these models promise to help elucidate the regulation of leaf form and provide essential insights into shape regulation in eukaryotic systems. The proposed research is deeply interdisciplinary, working at the interface of computer science and developmental biology. Falling directly at the intersection of the Tsiantis lab's expertise in studying the molecular determinants of leaf form and my expertise in computational modeling of plant development, it fully exploits our relative strengths. Thus providing an ideal vehicle to facilitate essential training while addressing a fundamental research problem.";159460,8;159460,8;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;DE;;;;1;0;0;1;0;0 194359;645684;Immuno-NanoDecoder;SIGNED;H2020-EU.1.3.3.;MSCA-RISE-2014;H2020;Nanostructured molecular decoders for the quantitative, multiplexed, layer-by-layer detection of disease-associated proteins;2015-04-01;2019-03-31;;"The long-range goal of this project is to develop a molecular nanodevice, based on nucleic acid-protein conjugates, for the multiplexed, quantitative imaging of biomarkers in tissue samples and cultured cells. The Immuno-nanodecoder will be used for the accurate molecular characterization of skin cancer (melanoma) and glycogenosis type II cellular models and to evaluate the in vitro response to experimental therapies. The nanodevices (nanodecoders) will consist of self-assembled DNA nanostructures that can reversibly change their fluorescence signal output in response to hybridization to nucleic acid sequences, or to a specific enzymatic reaction. Each nanodevice will be coupled to a specific molecular probe, such as an antibody, peptide, or protein that uniquely recognize disease biomarkers. The coupling will allow the nanodecoder to detect biomarker presence and distribution in cells and tissues, in a layer-by-layer fashion, using optical fluorescence microscopy. The number of biomarkers that can be detected will be limited only by the capacity to design nanodecoders with differing specificities, which is essentially unlimited. The creation of nanodecoders and optimization of their function will greatly advance biomarker imaging, which currently lacks a high-throughput, convenient method for the in situ, quantitative microscopic analysis of altered tissue regions. This project will be driven by knowledge exchange and the expertise of an interdisciplinary team comprised of both early-stage and experienced university and hospital researchers. Complementary research programs, ranging from nanotechnology to molecular medicine and pathology will support each step of the developmental and applicative parts of the project towards the achievement of its objectives. Funding of this program will enable long-term, transformative collaborations that will contribute to the integration and collaboration of research groups between European Countries and key Third Countries.";441000;441000;H2020-MSCA-RISE-2014;/MSCA-RISE;UNIVERSITA DEGLI STUDI DI ROMA TOR VERGATA;IT;"UNIVERSITY OF LINCOLN;AZIENDA SANITARIA UNIVERSITARIA INTEGRATA DI UDINE";"UK;IT";;1;0;0;1;0;0 193883;642080;SAF21;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2014-ETN;H2020;Social Science Aspects of Fisheries for the 21st Century;2015-01-01;2018-12-31;;SAF21 is an interdisciplinary and intersectoral network that embeds the social scientists of the future into EU fisheries management systems. It trains experts in analysis of human social behaviour for the better management of socio-ecological complex systems such as fisheries. Behaviour of fishers is complex as trust building and norms acceptance influence compliance with fishing regulations in unpredictable ways. The desired behaviour of fishers is often different from the actual subsequent one as those involved adapt to and find ways around new regulatory regimes, often with catastrophic consequences on resources. Therefore, an integrated understanding of the fine mechanisms governing fishers’ behaviour in relation with the regulative processes is needed, to the benefit of decision makers, fishing industry and the environment alike. Academic research and training have insufficiently reflected this need. SAF21 will contribute to rectifying this by training researchers in using tools of the 21st century, e.g. computational sociology techniques, to analyse this topic from a multitude of angles: public understanding of fisheries, trust and norms, social and regulative norms, social marketing of fisheries norms, stakeholders interaction in different management systems and socio-economic resilience. This knowledge will initiate the development of innovative management strategies, especially when it comes to shifting to new regulatory regimes. The wide-ranging training envisaged will offer a structured doctoral training in academic and transferable skills in addition to highly intersectoral non-academic mobility opportunities. Thus, the SAF21 candidates will have the necessary skills and experience to cross disciplines and work sectors. SAF21 will provide researchers the opportunity to fulfill their scientific social responsibility at a higher level than conventional doctoral programs, by ensuring significant time and training for public engagement and outreach.;2724033,96;2724033,96;H2020-MSCA-ITN-2014;/MSCA-ITN-ETN;UNIVERSITETET I TROMSOE;NO;"THE MANCHESTER METROPOLITAN UNIVERSITY;CENTRO TECNOLOGICO DEL MAR - FUNDACION CETMAR;MAPIX TECHNOLOGIES LTD;MATIS OHF;UNIVERSITEIT UTRECHT;SYNTESA APS;HASKOLI ISLANDS";"UK;ES;IS;NL;DK";;1;0;0;1;0;0 220954;825722;DIAdIC;SIGNED;H2020-EU.3.1.3.;SC1-BHC-23-2018;H2020;Evaluation of Dyadic Psychoeducational Interventions for People with Advanced Cancer and their Informal Caregivers (DIAdIC): An international randomized controlled trial;2019-01-01;2023-12-31;;Background: Advanced cancer affects millions of Europeans each year. The provision of adequate and cost-effective psychosocial and educational support for both patients and their frequently overburdened family caregivers is highly relevant from an economic, a healthcare and a prevention perspective. Aims: The DIAdIC project is an interdisciplinary, cross-national project to evaluate the effectiveness and cost-effectiveness of two psycho-educational dyadic interventions, i.e. interventions that target the patient and family caregiver together. One intervention is a web-based e-health intervention, one is nurse-led face-to-face intervention. Secondary aims are to assess the interventions' effects on vulnerable subgroups (e.g. people with a lower socioeconomic position), their effectiveness in different healthcare systems, and their suitability as perceived by end-users. Concept and methods: The two interventions are tailored to dyads' needs and have 5 core components: (1) supporting family involvement, (2) reducing hopelessness, (3) increasing coping effectiveness, (4) reducing uncertainty and (5) teaching symptom management. They are based on existing interventions, developed in the USA, that have been shown to improve quality of life of both patient and family caregiver. The effectiveness of each of the interventions (compared to care as usual) will be assessed by way of an international randomized controlled trial in people with advanced cancer and their primary informal carers. The project includes a full health-economic evaluation and a thorough process evaluation. Impact: The project advances the state of the art in several ways, e.g. by providing innovative healthcare interventions (including a eHealth solution) that embrace the philosophy and principles of early palliative care. The interventions will be suitable for implementation across diverse healthcare systems. Public involvement methods ensure the input of stakeholders throughout the project.;4277875;4277875;H2020-SC1-2018-Single-Stage-RTD;/RIA;VRIJE UNIVERSITEIT BRUSSEL;BE;"AZIENDA UNITA SANITARIA LOCALE DI REGGIO EMILIA;UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN;THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN;UNIVERSITEIT GENT;KOBENHAVNS UNIVERSITET;THE QUEEN'S UNIVERSITY OF BELFAST;EUROPEAN ASSOCIATION OF PALLIATIVE CARE;EUROPEAN CANCER PATIENT COALITION;ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM;KING'S COLLEGE LONDON";"IT;IE;BE;DK;UK;NL";;1;0;0;1;0;0 220956;825750;INADVANCE;SIGNED;H2020-EU.3.1.3.;SC1-BHC-23-2018;H2020;Patient-centred pathways of early palliative care, supportive ecosystems and appraisal standard;2019-01-01;2022-12-31;;"Due to the increased incidence, prevalence and mortality of chronic diseases and multimorbidity, the need of palliative care (PC) resources is a challenge for health and social care systems. However, currently, access to PC remains inconsistent and, due to the ageing population, it is expected an increase in the rate of people requiring this kind of care over the next 25 years. The project Patient-centred pathways of early palliative care, supportive ecosystems and appraisal standard (INADVANCE) proposes a novel model of PC based on early integration and personalized pathways addressed specifically to older people with complex chronic conditions. Thus, the overall aim of INADVANCE is to improve the benefit of PC through the design of effective, replicable and cost-effective early PC interventions centred-on and oriented-by the patients. Interventions are defined for/orientated on patients, families, informal caregivers, and front-line care professionals. In order to achieve this main goal, INADVANCE will produce the following evidence-based outputs to assist care professionals, service managers and policy and decision-makers in their scalability and replicability: a) stratification tools to identify potential beneficiaries of early PC actions; b) optimized interventions co-designed by needs and preferences from patients and their relatives; c) eHealth tools addressed to empower palliative patients ecosystem; d) policy recommendations and clinical guidelines addressed to service providers and policy and decision makers; e) an appraisal standard and dashboard facilitating a critical and comprehensive comparison between actions and interventions derived from the project. The INADVANCE consortium brings together leading interdisciplinary academic, clinical and technological partners from EU organizations actively responding challenges from health and social care systems and policy-makers in the field.";4017970;4017970;H2020-SC1-2018-Single-Stage-RTD;/RIA;UNIVERSITAT DE VALENCIA;ES;"NIVELY;ARISTOTELIO PANEPISTIMIO THESSALONIKIS;IRMANDADE DA SANTA CASA DA MISERICORDIA DA AMADORA IPSS;FUNDACION PARA LA INVESTIGACION DEL HOSPITAL UNIVERSITARIO LA FE DE LA COMUNIDAD VALENCIANA;UNIVERSITY OF LEEDS;AGE PLATFORM EUROPE;UNIVERSITAT POLITECNICA DE VALENCIA;ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM;HIGHLAND HEALTH BOARD;SALUMEDIA TECNOLOGIAS SL";"FR;EL;PT;ES;UK;BE;NL";;1;0;0;1;0;0 220933;819960;NewHuman;SIGNED;H2020-EU.1.1.;ERC-2018-COG;H2020;Pathways to humanity: Adaptive niche diversity at the origins of the human lineage;2019-07-01;2024-06-30;;"For almost 100 years, the evolution of humans has been summarized as a transition from small-brained bipeds with an ape-like body plan (referred to as australopiths), to large-brained striding bipeds with a human-like body plan (members of the genus Homo). This characterisation dominates popular perception of human evolution in the public sphere. However, three newly discovered fossil human (hominin) species (H. naledi, H. floresiensis and Australopithecus sediba) do not fit this simple transitional model in either morphology or time (the former two surviving contemporaneously with modern humans), and have re-ignited debate about the origin of the Homo lineage, including perceptions of the earliest putative Homo species, H. habilis. These new fossils raise fundamental questions about the ecological niches occupied by hominins and the inferred transitions between niches throughout human evolution. With NewHuman, I will pioneer a novel, interdisciplinary and holistic approach using cutting-edge analyses of internal structures of fossil hominin teeth and bones to reconstruct the adaptive niche of these enigmatic species and test whether there is an unrecognized adaptive branch on the human family tree. Specifically, NewHuman will employ ground-breaking imaging techniques and analytical tools to reveal never-before-examined tooth and bone structures in these hominins. In doing so, it will 1) characterize the behaviour of these enigmatic species and place them more firmly into their ecological environment; and 2) elucidate the adaptive strategy that was likely the transition from australopith-like hominin species to later Homo, but which also represents a highly successful lifeway that persisted for over 2 million years alongside the evolving human lineage. By achieving these ambitious aims, NewHuman will have a significant impact on hypotheses about human evolution, and could result in a paradigm shift that overturns current views on human evolutionary history.";1998643,75;1998643,75;ERC-2018-COG;/ERC-COG;UNIVERSITY OF KENT;UK;"TECHNISCHE UNIVERSITAET WIEN;UNIVERSITY OF THE WITWATERSRAND JOHANNESBURG;LAKEHEAD UNIVERSITY";"AT;ZA;CA";;1;0;0;1;0;0 220921;819734;VINCULUM;SIGNED;H2020-EU.1.1.;ERC-2018-COG;H2020;Entailing Perpetuity: Family, Power, Identity. The Social Agency of a Corporate Body(Southern Europe, 14th-17th Centuries);2019-06-01;2024-05-31;;"Few legal phenomena have been so relevant to premodern southern Europe societies as entails, a specific strategy that evolved to protect family inheritances, thus enabling the reproduction of elite social status. The VINCULUM project aims to explain how entailment became possible, how it functioned, and why it lasted for so many centuries. The project rests on the innovative theoretical claim that entails, as corporate bodies, functioned as a key social agent, created and acting within societies for which non-personal legal subjects were normal. Building on the Portuguese-Iberian case, and on the extensive research already carried out by me and my team, I propose to study 'entailment' as a diverse but pivotal practice, one embedded in law, aristocratic discourse, and kinship-based organization, and to carry out comprehensive analysis that explores this global nature. The research approach systematically breaks with traditional research frontiers: cases will extend from the 14th to 17th century in both continental and Atlantic spaces, and include both comparative perspectives and the study of later social reconfigurations. VINCULUM will be anchored in extended research in public archives and on unprecedented access to extensive private family archives, which have been opened to research by the ARQFAM program I have led since 2008. Data collection will allow for the construction of a large database, gathering all documents relating to each entail, under a theoretical model that seeks to reconstruct past information systems, thus testing a novel methodology developed in my previous research. The database that will gather c.7000 thousand entails, enabling systematic inquiries organized around the new conceptual definitions proposed by the project. The research will be strongly interdisciplinary, engaging with historical anthropology and archival science in order to construct a proper theoretical model for understanding this crucial legal and social phenomenon.";1591450;1591450;ERC-2018-COG;/ERC-COG;UNIVERSIDADE NOVA DE LISBOA;PT;;;;1;0;0;1;0;0 207475;737116;ByAxon;SIGNED;H2020-EU.1.2.1.;FETOPEN-01-2016-2017;H2020;Towards an active bypass for neural reconnection;2017-01-01;2020-12-31;;"ByAxon is devoted to the development of a new generation of sensors and electrodes based on nanotechnology materials for neural interfacing. We aim to design and build a prototype of an active implant that could work directly at the spinal cord (SC) level. This implant will be primary focused on restoring the transmission of electrical signals in the injured SC, acting as an active local bypass, something not possible with current technology. Further applications might include deep brain stimulation or retinal implants, among others. Current neural interfacing approaches are based on detecting electric potentials at the brain level, and/or triggering functional electrical stimulation (FES) through electrodes at muscular or SC levels. Important present drawbacks are the large number of cables and electrodes they require and, specially, the lack of sensory feedback. The ultimate non-contact sensing devices (magnetoencephalography) detect magnetic-field pulses generated by potentials at the brain, but require cryogenic temperatures, and, hence, are not portable. We will exploit here the enhanced properties of nanostructured materials to develop improved room temperature magnetoresistance-based high-resolution magnetic sensors. This will allow tackling not only the brain but also the SC directly. We pursuit a novel integrated interface comprising both sensing and stimulation at the SC level. To reach this aim, we will develop FES electrodes of enhanced adhesion and efficiency by using nanowire coatings. ByAxon is supported by an interdisciplinary consortium, going from material scientists and electronic experts to biologists and clinicians. Our nanotechnology-based approach offers a novel perspective and will be complementary to, but independent from, present neural regenerative techniques. Our technology promises significant outcomes towards the development of an active local bypass and it has the potential to provide much-needed breakthroughs in future neuromedicine.";3752057,5;3752057,5;H2020-FETOPEN-1-2016-2017;/RIA;FUNDACION IMDEA NANOCIENCIA;ES;"SERVICIO DE SALUD DE CASTILLA LA MANCHA;SCUOLA INTERNAZIONALE SUPERIORE DI STUDI AVANZATI DI TRIESTE;AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS;Mfd-diagnostics GmbH;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS";"ES;IT;DE;FR";;1;0;0;1;0;0 220826;812880;NOWELTIES;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2018;H2020;Joint PhD Laboratory for New Materials and Inventive Water Treatment Technologies. Harnessing resources effectively through innovation;2019-02-01;2023-01-31;;Future challenges, including climate change and the resulting unpredictability of precipitation patterns and temporal or permanent water scarcity, generate a high diversity of demands on water treatment technologies obliging them to be able to cater towards a variety of source and target water qualities across multiple scales, depending on application. It is evident that this will generate a market pull towards the development of new water treatment technologies, employing new materials or improving the integration of existing technologies. However, the integration of research and innovation within the water sector needs to be supported by education of a new generation of interdisciplinary trained wastewater professionals able to face future challenges and implement wastewater-related directives in practice. The primary objective of NOWELTIES is to organize a platform (European Joint Doctorate) that will provide cutting edge training opportunities for the education of tomorrow`s water treatment experts. The core activity is the research programme (composed of 14 individual research projects) aimed at development of inventive water treatment technologies (advanced biological treatments, inovative oxidation processes, hybrid systems) that allow catering for the varied treatment demands for a plethora of interconnected streams arising from recycling loops. These technologies will be able to control contamination by organic micropollutants (OMPs) and improve recovery of water across a diversity of scales enabling a smart combination of decentralized and centralised approaches. Besides a holistic training in the field of wastewater treatment dealing with state-of-the-art technologies, experimental techniques and knowledge management methodologies, NOWELTIES will provide a unique training approach to learning complex complementary skills leading to independent and critical thinking which seeks for originality and innovation.;3422141,64;3422141,64;H2020-MSCA-ITN-2018;/MSCA-ITN-EJD;FUNDACIO INSTITUT CATALA DE RECERCA DE L'AIGUA;ES;"RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN;TECHNISCHE UNIVERSITAET MUENCHEN;FACULTY OF TECHNOLOGY AND METALLURGY UNIVERSITY OF BELGRADE;UNIVERSIDAD DE SANTIAGO DE COMPOSTELA;INSTITUT ZA FIZIKU;SVEUCILISTE U ZAGREBU FAKULTET KEMIJSKOG INZENJERSTVA I TEHNOLOGIJE;SVEUCILISTE U ZAGREBU, FAKULTET STROJARSTVA I BRODOGRADNJE;UNIVERSITA DEGLI STUDI DI FERRARA";"DE;RS;ES;HR;IT";;1;0;0;1;0;0 220827;812890;ArthritisHeal;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2018;H2020;Establishing the molecular fundamentals of arthritic diseases – a step forward to Heal Arthritis;2019-03-01;2023-02-28;;"In the ArthritisHeal project 7 universities and 2 companies, together with 8 associated partners, will train 12 young researchers and will discover novel therapeutic targets for two rheumatic diseases: osteoarthritis (OA) and rheumatoid arthritis (RA). The project will focus on the role of pro-resolving lipids, which play an important role in both diseases by stimulating resolution of inflammation. Both OA and RA cause pain and deformation of joints, with inflammation playing large role in the pathogenesis of both diseases. Current therapies, focused on inhibition of inflammation, are insufficient to cure rheumatic diseases. By exploiting pro-resolving mechanisms, novel therapeutic targets will be discovered in this project, ultimately improving RA and OA treatment. During the project both clinical samples and animal models will be used to study mode of action and verify clinically relevant lipids. Novel lipids discovered in pre-clinical models are validated in clinical samples, and the mode-of-action of known lipids will be determined in pre-clinical models. The consortium of academic and industrial beneficiaries with leading expertise in rheumatology, lipidomics, immunology and data analysis will provide scientific and technology training to ESRs. Associated partners will provide secondment opportunities and training, e.g. in regulatory and IP issues and career development. Each ESR will follow a personalised training programme combining clinical, biological and chemical insights to solve challenges in the development of treatments for rheumatic diseases. The ESRs will receive training both in an academic as well as an industrial setting. By studying the role of pro-resolving lipids in two important rheumatic diseases in conjunction, the consortium will: - Train young researchers in the interdisciplinary approach necessary to develop treatments for complex diseases. - Validate therapeutic targets in important pro-resolving lipid pathways.";3297271,32;3297271,32;H2020-MSCA-ITN-2018;/MSCA-ITN-ETN;ACADEMISCH ZIEKENHUIS LEIDEN;NL;"IMMUNOTECH SAS;PHARMAGNOSE VIOTECHNOLOGIKI ANONYMI ETAIREIA;KAROLINSKA INSTITUTET;EBERHARD KARLS UNIVERSITAET TUEBINGEN;QUEEN MARY UNIVERSITY OF LONDON;UNIVERSITY OF GLASGOW;KATHOLIEKE UNIVERSITEIT LEUVEN;CARDIFF UNIVERSITY";"FR;EL;SE;DE;UK;BE";;1;0;0;1;0;0 220875;818556;TotipotentZygotChrom;SIGNED;H2020-EU.1.1.;ERC-2018-COG;H2020;Mechanisms of chromatin organization and reprogramming in totipotent mammalian zygotes;2020-02-01;2025-01-31;;"Totipotency, the developmental potential of a cell to give rise to all cell types, is naturally achieved when differentiated egg and sperm fuse to form the one-cell zygote. How chromatin is epigenetically reprogrammed to totipotency within hours after fertilisation remains a central question in biology. We aim to address this by investigating the mechanisms of reprogramming and the spatial reorganisation of chromatin in mammalian zygotes. Our interdisciplinary approach combines mechanistic cell biology with genetics and genomics to understand how chromatin reorganisation promotes totipotency and to identify key regulators of this process in zygotes. Molecular insights into reprogramming to totipotency are crucial to understand the essential zygotic stage of sexually reproducing species. A better understanding of how cells naturally reprogram chromatin to totipotency, a state upstream of pluripotency, has the potential to improve induced reprogramming technology and revolutionize regenerative medicine. Our aim is to understand how chromatin is reprogrammed to totipotency. To reach this ambitious goal: 1) We will discover new general concepts of genome organization, as well as reprogramming-specific aspects, by capitalising on our recently developed single-nucleus Hi-C method to dissect spatial reorganisation of chromatin in zygotes. We will investigate the relationship between chromatin reorganisation and transcription. 2) We will uncover mechanisms of zygotic reprogramming by elucidating the loci and factors that support active DNA demethylation during reprogramming of the paternal genome. 3) We will illuminate the origins and contributions of the oocyte since the factors responsible for reprogramming likely reside as proteins or RNA in the unfertilized egg. Overall, these studies will provide novel insights into how chromatin is reprogrammed and spatially reorganised towards a totipotent state that facilitates zygotic genome activation.";2000000;2000000;ERC-2018-COG;/ERC-COG;INSTITUT FUER MOLEKULARE BIOTECHNOLOGIE GMBH;AT;;;;1;0;0;1;0;0 219198;824079;OCRE;SIGNED;H2020-EU.1.4.1.3.;INFRAEOSC-01-2018;H2020;Access to Commercial Services Through the EOSC-hub;2019-01-01;2021-12-31;;"The Open Cloud for Research Environments consortium combines the expertise of four partners to enable access and drive the adoption and use of commercial digital services by the European research community. Essential for interdisciplinary research, these services include: • Commodity type commercial digital services, such as: • Infrastructure as a Service (IaaS) and Platform as a Service (PaaS), providing compute, storage, network and related services, and a platform allowing customers to develop, run, and manage applications as a public cloud service. • Software as a Service (SaaS), an on-demand software licensing and delivery model in which software is used by the customer on a subscription basis and is hosted by the supplier as a public cloud service. File storage (sync and share), online collaboration, simulation and virtualisation tools are example services. • Secure Earth Observation commercial services, which make use of the Copernicus Data and Information Access Services (DIAS). After gathering user requirements, the OCRE will manage the adoption funds and buy resources from the selected suppliers (OCRE will act as customer) and make cloud resources available to institutions. Such a delivery vehicle is effective and efficient for the supply as well as the demand side. Service adoption is the key focus of this work. A legal and technical mechanism (The OCRE Business Management Platform) will be created to integrate a range of these commercial services into the EOSC hub in order to make them more easily available to researchers.";14362500;12000000;H2020-INFRAEOSC-2018-1;/RIA;GEANT VERENIGING;NL;"TRUST-IT SRL;RHEA SYSTEM;EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH";"IT;BE;CH";;1;0;0;1;0;0 220844;817493;ICORDA;SIGNED;H2020-EU.1.1.;ERC-2018-COG;H2020;Ice CORe DAting tools revisited to infer the dynamic of glacial – interglacial transitions over the last 1.5 million years;2019-09-01;2024-08-31;;The Quaternary period (last 2600 thousands of years, hereafter ka) is the ideal period to evaluate our understanding of climate processes with general circulation models (GCM) used for prediction of future climate. During this period, the largest climate changes are glacial – interglacial transitions, hereafter terminations, the last termination being a classical benchmark for GCM. The rhythm of terminations changed from a world associated with a 40 ka periodicity to a world associated with a 100 ka glacial – interglacial periodicity between 1250 and 700 ka. The cause for this transition is a long debated question highlighting that the causes and mechanisms of terminations are still poorly understood. The timing and amplitudes of terminations indeed result from multiple influences of insolation forcing, ice sheet size, atmospheric greenhouse gases (GHG) concentration as well as shorter (millennial) scale climate variability. The big challenge of ICORDA consists in solving major puzzles on the mechanisms of terminations by deciphering these different influences using two key Antarctic ice core records: EPICA Dome C covering the last 800 ka and an ice core to be drilled in the coming years and covering the last 1500 ka. While ice cores provide unique continuous and high resolution climatic and GHG records, they are still too poorly dated on long timescales to address the aforementioned challenge. ICORDA aims at rethinking the way ice core chronology is built for decreasing drastically the associated uncertainties. This will be done by (1) developing a mechanistic approach for the interpretation of isotopic tracers used for ice core dating and (2) combining numerous low to mid latitude ice core tracers to provide a global picture of climate change during terminations. The strategy involves interdisciplinarity between climate, geochemistry, ecophysiology and innovative instrumental developments as well as field, laboratory experiments and modeling.;1994100;1994100;ERC-2018-COG;/ERC-COG;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FR;;;;1;0;0;1;0;0 219816;825410;ONCOBIOME;SIGNED;H2020-EU.3.1.2.;SC1-BHC-03-2018;H2020;Gut OncoMicrobiome Signatures (GOMS) associated with cancer incidence, prognosis and prediction of treatment response.;2019-01-01;2023-12-31;;Beyond the role the intestinal metagenome plays in regulating multiple physBeyond its role in regulating multiple physiological functions that impact health, the intestinal metagenome is implicated in cancer initiation, progression and responses to therapies, even for extraintestinal neoplasia. Hence, there is an urgent need to fully identify and functionally characterize minimalist commensal ecosystems relevant to cancer, with reliable and robust methods, to validate cancer-associated gut microbiome fingerprints of high clinical relevance, and to develop diagnosis tools that will become part of the oncological arsenal for the optimization and personalization of therapy. Based on retro-and pro-spective studies, with large discovery and validation cohorts enrolling >9,000 cancer patients across 10 countries, ancillary to ongoing innovative clinical trials or FDA/EMA approvals across 4 frequent cancer types, ONCOBIOME will pursue the following aims: 1/ identify and validate core or cancer-specific Gut OncoMicrobiome Signatures (GOMS) associated with cancer occurrence, prognosis, response to, or progression on, therapy (polychemotherapy, immune checkpoint inhibitors, dendritic cell vaccines) or adverse effects, 2/ decipher the functional relevance of these cancer-associated gut commensal ecosystems in the regulation of host metabolism, immunity and oncogenesis, 3/ integrate these GOMS with other oncology hallmarks (clinics, genomics, immunomics, metabolomics) 4/ design optimal companion tests, based on those integrated signatures to predict cancer occurrence and progression. With high carat interdisciplinary experts, ONCOBIOME expects to validate cancer or therapy-specific Gut OncoMicrobiome Signatures (GOMS) across breast, colorectal, melanoma and lung cancers adjusting for covariates, to unravel the mode of action of these GOMS in innovative platforms, thus lending support to the design of cancer preventive campaigns using well characterized pre-and pro-biotics.;14994551,25;14994551,25;H2020-SC1-2018-Single-Stage-RTD;/RIA;INSTITUT GUSTAVE ROUSSY;FR;"THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE;Masarykova univerzita;STICHTING KATHOLIEKE UNIVERSITEIT;UNICANCER;GBG FORSCHUNGS GMBH;EVERIMMUNE;CENTRE HOSPITALIER DE L'UNIVERSITEDE MONTREAL;HALIODX;ALGOE SA;CHARITE - UNIVERSITAETSMEDIZIN BERLIN;IIGM FOUNDATION;UNIVERSITA DEGLI STUDI DI TRENTO;KAROLINSKA INSTITUTET;UNIVERSITATSKLINIKUM ERLANGEN;FONDAZIONE IRCCS ISTITUTO NAZIONALE DEI TUMORI";"UK;FR;CZ;NL;DE;CA;IT;SE";;1;0;0;1;0;0 220822;811234;ENFORCE;SIGNED;H2020-EU.1.1.;ERC-2018-COG;H2020;ENgineering FrustratiOn in aRtificial Colloidal icEs:degeneracy, exotic lattices and 3D states;2020-01-01;2024-12-31;;"Geometric frustration, namely the impossibility of satisfying competing interactions on a lattice, has recently become a topic of considerable interest as it engenders emergent, fundamentally new phenomena and holds the exciting promise of delivering a new class of nanoscale devices based on the motion of magnetic charges. With ENFORCE, I propose to realize two and three dimensional artificial colloidal ices and investigate the fascinating manybody physics of geometric frustration in these mesoscopic structures. I will use these soft matter systems to engineer novel frustrated states through independent control of the single particle positions, lattice topology and collective magnetic coupling. The three project work packages (WPs) will present increasing levels of complexity, challenge and ambition: (i) In WP1, I will demonstrate a way to restore the residual entropy in the square ice, a fundamental longstanding problem in the field. Furthermore, I will miniaturize the square and the honeycomb geometries and investigate the dynamics of thermally excited topological defects and the formation of grain boundaries. (ii) In WP2, I will decimate both lattices and realize mixed coordination geometries, where the similarity between the colloidal and spin ice systems breaks down. I will then develop a novel annealing protocol based on the simultaneous system visualization and magnetic actuation control. (iii) In WP3, I will realize a three dimensional artificial colloidal ice, in which interacting ferromagnetic inclusions will be located in the voids of an inverse opal, and arranged to form the FCC or the pyrochlore lattices. External fields will be used to align, bias and stir these magnetic inclusions while monitoring in situ their orientation and dynamics via laser scanning confocal microscopy. ENFORCE will exploit the accessible time and length scales of the colloidal ice to shed new light on the exciting and interdisciplinary field of geometric frustration.";1850298;1850298;ERC-2018-COG;/ERC-COG;UNIVERSITAT DE BARCELONA;ES;;;;1;0;0;1;0;0 220899;819318;Agglomerates;SIGNED;H2020-EU.1.1.;ERC-2018-COG;H2020;Infinite Protein Self-Assembly in Health and Disease;2019-04-01;2024-03-31;;"Understanding how proteins respond to mutations is of paramount importance to biology and disease. While protein stability and misfolding have been instrumental in rationalizing the impact of mutations, we recently discovered that an alternative route is also frequent, where mutations at the surface of symmetric proteins trigger novel self-interactions that lead to infinite self-assembly. This mechanism can be involved in disease, as in sickle-cell anemia, but may also serve in adaptation. Importantly, it differs fundamentally from aggregation, because misfolding does not drive it. Thus, we term it “agglomeration”. The ease with which agglomeration can occur, even by single point mutations, shifts the paradigm of how quickly new protein assemblies can emerge, both in health and disease. This prompts us to determine the basic principles of protein agglomeration and explore its implications in cell physiology and human disease. We propose an interdisciplinary research program bridging atomic and cellular scales to explore agglomeration in three aims: (i) Map the landscape of protein agglomeration in response to mutation in endogenous yeast proteins; (ii) Characterize how yeast physiology impacts agglomeration by changes in gene expression or cell state, and, conversely, how protein agglomerates impact yeast fitness. (iii) Analyze agglomeration in relation to human disease via two approaches. First, by predicting single nucleotide polymorphisms that trigger agglomeration, prioritizing them using knowledge from Aims 1 & 2, and characterizing them experimentally. Second, by providing a proof-of-concept that agglomeration can be exploited in drug design, whereby drugs induce its formation, like mutations can do. Overall, through this research, we aim to establish agglomeration as a paradigm for protein assembly, with implications for our understanding of evolution, physiology, and disease.";2574819;2574819;ERC-2018-COG;/ERC-COG;WEIZMANN INSTITUTE OF SCIENCE;IL;;;;1;0;0;1;0;0 220876;818602;MarsFirstWater;SIGNED;H2020-EU.1.1.;ERC-2018-COG;H2020;The physicochemical nature of water on early Mars;2019-06-01;2024-05-31;;"Concepts of large bodies of glacial ice and liquid standing water, a robust hydrological cycle, and a rich Martian history of climate change are part of the current consensus model for early Mars. However, questions still poorly constrained include: a precise understanding of the inventory of water during the first billion years of Mars history and its early evolution on both global and local scales; whether liquid or solid H2O dominated, for what duration of time and where the water resided; what were the host-rock weathering rates and patterns and the physicochemical parameters defining such interactions; what specific landforms and mineralogies were generated during those periods; and what implications all these processes had on the possible inception of life on Mars. These fundamental questions represent large uncertainties and knowledge gaps. Therefore, a quantitative understanding of the basic characteristics of water on early Mars is very much needed and is the focus of this proposal. This application outlines a plan for my research in the next five years, and explains how I propose to fully characterize the aqueous environments of early Mars through a quantitative and truly interdisciplinary investigation. Spacecraft mission-derived datasets will be consistently used to test hypotheses through paleogeomorphological reconstructions, geochemical modeling, mineralogical studies, and astrobiological investigations. The derived results will produce hard constraints on the physical evolution, chemical alteration and habitability of surface and near-surface aqueous environments on early Mars. The planned investigations will benefit from the combination of working with first-hand data from ongoing Mars missions and with the state-of-the-art laboratory tools at the host institution. The final expected result will be a complete understanding of the physicochemical nature of water on early Mars, also opening new paths for the astrobiological exploration of the planet.";1998368;1998368;ERC-2018-COG;/ERC-COG;AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS;ES;UNIVERSIDAD AUTONOMA DE MADRID;ES;;1;0;0;1;0;0 220912;819533;INSCONS;SIGNED;H2020-EU.1.1.;ERC-2018-COG;H2020;"Addressing Global Challenges through International Scientific Consortia (INSCONS); Case studies in biomedicine, the geosciences, and nuclear fusion research";2019-09-01;2024-08-31;;INSCONS is a groundbreaking, large-scale examination of the organisational dynamics of international scientific consortia (ISCs) and the interactions of these consortia with broader scientific communities, national bureaucracies, and industry. ISCs are very complex organisations with work being carried out at geographically dispersed sites, and involving international stakeholder groups from across the realms of science, policy, and industry. As these ISCs are becoming more important in efforts to address global challenges in areas such as health, the environment, and clean energy, our understanding of the distinctive organizational dynamics governing these consortia has lagged behind. Accordingly, there is a pressing need for novel organisational theory and frameworks that will advance our understanding of ISCs. INSCONS is an ambitious effort to address this need, using a comparative, interdisciplinary approach. Three case studies of large, international ISCs in nuclear fusion research, biomedicine, and the geosciences are at the core of INSCONS. The INSCONS project will examine four aspects of these ISCs. It will 1) Map the internal organisational dynamics of ISCs using interviews, bibliometric network analyses, and ethnographic field studies on everyday work in ISCs. 2) It will study ISCs’ interactions with the broader scientific community by conducting a survey among researchers in the scholarly fields ISCs operate in, and by analysing these fields’ co-authorship networks. 3) It will examine the (inter)national political processes and bureaucratic wrangling shaping ISCs. 4) It will examine relationships of dependency and influence between ISCs and industry through case studies as well as analyses of patenting and publication activities. Taken together, the project outputs of INSCONS will bring into clear focus the sociology and politics, as well as the operational complexities that govern this important, new organisational form in contemporary science.;1997021;1997021;ERC-2018-COG;/ERC-COG;UNIVERSITEIT LEIDEN;NL;;;;1;0;0;1;0;0 220910;819526;EVENTS;SIGNED;H2020-EU.1.1.;ERC-2018-COG;H2020;MAKING SENSE OF THE WORLD: COGNITIVE AND NEURAL PROCESSES UNDERPINNING HOW WE COMPREHEND, PREDICT AND REMEMBER EVENTS;2019-10-01;2024-09-30;;During our waking lives we are continuously exposed to a vast amount of information about the world around us. Yet somehow we make sense of this information and we consciously experience a coherent and ordered world, where life proceeds in a sequence of events with recognisable beginnings and ends. How the human mind manages to re-process continuous experience into these event-units is remarkably poorly understood. To date, the field has been held back by the significant methodological challenges to studying complex mental processes operating in naturalistic situations. The EVENTS project will address these challenges in an ambitious and interdisciplinary programme of research, involving behavioural studies (including immersive virtual reality), cutting-edge functional MRI and neuropsychology in specialised populations. Across a series of studies, EVENTS will establish how information processed in independent neural modules is combined within a mental “event model”, which is an overarching representation of the important features of any given situation . The project will discover how event models are updated and how they are instantiated in the brain. EVENTS will also define how event models shape our perception and memory of everyday situations and how they interact with stored knowledge. Finally, we will integrate these novel findings with previous disparate lines of evidence into a neurocognitive model of event processing. The knowledge generated by EVENTS will have far-reaching impact across the social, cognitive and neuro- sciences, shedding light on long-standing debates about how we internally represent the external world, how beliefs about the state of the world interact with how we perceive and remember events, and on how we perceive the passage of time. Moreover, the development of a detailed cognitive and neural model of event processing will represent a vital step towards a mechanistic account of conscious experience.;1947983;1947983;ERC-2018-COG;/ERC-COG;THE UNIVERSITY OF SUSSEX;UK;;;;1;0;0;1;0;0 215644;798480;VOLCANOWAVES;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;State of unrest of active VOLCANOes through advanced seismic WAVES analysis - An application to eruption forecast modelling.;2018-09-01;2020-09-28;;"Volcanic eruptions have a high social and economic impact on a global scale, and they can be responsible for severe consequences into climate changes and on population’s life, determining severe damages to buildings, crops, telecommunications and air traffics. The security and protection of populations in sites exposed to risk requires the improvement of our ability to forecast volcanic eruptions and the development of better alert protocols, in order to take preventive measures and minimize their effects in both human and economic terms. Volcano monitoring is mainly based on the analysis of seismic signals, in order to found precursory events which appear before an eruption. Due to the big amount of seismic data nowadays acquired by the volcanic observatory, in a volcano crisis it became difficult the manual supervised detection and classification carried out by expert technicians. So an automatic volcano-seismic signal processing is crucial to quickly detect and analyse the precursory seismicity and to correctly assess the population risk. This project is conceived to advance beyond-the-state-of-the-art providing tools for a better and more accurate automatic volcano-seismic signals detection and classification to obtain Early Warning Decision Making algorithms. This is a highly interdisciplinary project, where the Signal Processing, Machine Learning, Big Data, and Knowledge Management are combined with the Volcanic Seismology science. In order to carry out this project, seismic records from some volcanoes (in particular, Etna, Colima, Montserrat volcanoes) are available. The proposed strategy includes a new philosophy in database creation and new and innovative signal processing techniques, and will improve our ability to forecast volcanic eruptions. The proposed methodologies are new in the field of volcano-seismology, but researchers involved in the project have already applied them successfully in different contexts.";170121,6;170121,6;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;UNIVERSIDAD DE GRANADA;ES;;;;1;0;0;1;0;0 206126;705326;SWING;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-GF;H2020;Patterning Spin-Wave reconfIgurable Nanodevices for loGics and computing.;2016-11-01;2019-10-31;;"Spin-waves, i.e. propagating perturbations in the spin arrangement of magnetic materials, are envisioned to revolutionize the way information is carried and processed due to their multiplexing capability and absence of Joule losses. By bringing together the complementary expertise of “CUNY Advanced Science Research Center” (USA) and “Politecnico di Milano (PoliMi)” (Italy), the ‘SWING’ project addresses two major issues of current nanoscale magnonics: the efficient guidance of spin-waves in nanostructured materials and the study of spin-waves at the nanoscale. At CUNY, “Thermally assisted magnetic scanning probe lithography” (tam-SPL), recently conceived and demonstrated by the applicant, will be further developed and employed for nanopatterning magnonic devices in magnetic multilayers grown at PoliMi. In such devices, spin-waves will be efficiently guided and manipulated by defining reconfigurable topological features, such as magnetic domain walls, in continuous films, avoiding any detrimental scattering due to the physical interfaces created by conventional lithography. Furthermore, a novel, versatile tool for the nanoscale study of magnons will be realized, by combining Nitrogen-Vacancy magnetometry and scanning probe microscopy. Advanced magnetic characterization via optical methods, experiments at Brookhaven Synchrotron and access to the cutting-edge CUNY NanoFab facility will be pivotal complements in view of the research objectives. During the incoming phase, the acquired expertise and technologies developed at CUNY will be transferred to PoliMi, aiming to realize fully reconfigurable nanoscale magnonic logic devices. ‘SWING’ project aims to push magnonics forward, by means of an interdisciplinary approach which combines the excellent competence of the host organizations in magnetism, nanoscience, photonics and entrepreneurship. The candidate will acquire key comprehensive skills towards becoming an independent scientific and technological leader in Europe.";244269;244269;H2020-MSCA-IF-2015;/MSCA-IF-GF;POLITECNICO DI MILANO;IT;;;;1;0;0;1;0;0 220913;819536;ScienceGraph;SIGNED;H2020-EU.1.1.;ERC-2018-COG;H2020;Knowledge Graph based Representation, Augmentation and Exploration of Scholarly Communication;2019-05-01;2024-04-30;;"Despite an improved digital access to scientific publications in the last decades, the fundamental principles of scholarly communication remain unchanged and continue to be largely document-based. The document-oriented workflows in science have reached the limits of adequacy as highlighted by recent discussions on the increasing proliferation of scientific literature, the deficiency of peer-review and the reproducibility crisis. In ScienceGRAPH we aim to develop a novel model for representing, analysing, augmenting and exploiting scholarly communication in a knowledge-based way by expressing and linking scientific contributions and related artefacts through semantically rich, interlinked knowledge graphs. The model is based on deep semantic representation of scientific contributions, their manual, crowd-sourced and automatic augmentation and finally the intuitive exploration and interaction employing question answering on the resulting ScienceGRAPH base. Currently, knowledge graphs are still confined to representing encyclopaedic, factual information. ScienceGRAPH advances the state-of-the-art by enabling to represent complex interdisciplinary scientific information including fine-grained provenance preservation, discourse capture, evolution tracing and concept drift. Also, we will demonstrate that we can synergistically combine automated extraction and augmentation techniques, with large-scale collaboration to reach an unprecedented level of knowledge graph breadth and depth. As a result, we expect a paradigm shift in the methods of academic discourse towards knowledge-based information flows, which facilitate completely new ways of search and exploration. The efficiency and effectiveness of scholarly communication will significant increase, since ambiguities are reduced, reproducibility is facilitated, redundancy is avoided, provenance and contributions can be better traced and the interconnections of research contributions are made more explicit and transparent.";1996250;1996250;ERC-2018-COG;/ERC-COG;GOTTFRIED WILHELM LEIBNIZ UNIVERSITAET HANNOVER;DE;"TECHNISCHE INFORMATIONSBIBLIOTHEK (TIB);INSTITUT FUR ANGEWANDTE INFORMATIK (INFAI) EV";DE;;1;0;0;1;0;0 220550;828890;NARCISO;SIGNED;H2020-EU.1.2.1.;FETOPEN-01-2018-2019-2020;H2020;NAtuRal instability of semiConductors thIn SOlid films for sensing and photonic applications;2019-03-01;2022-02-28;;"NARCISO “NAtuRal instability of semiConductors thIn SOlid films for sensing and photonic applications” is an interdisciplinary project merging physics, chemistry, material science, fluid dynamics, and photonics with a high potential for applications and industrial scale-up of the relevant results. We propose to exploit the natural instability of thin solid films (solid state dewetting of silicon and germanium, SSD) to form complex patterns and nano-architectures (e.g. monocrystalline atomically-smooth structures, disordered hyperuniform metamaterials) that cannot be implemented with conventional methods. These patters will be used as: i) epitaxial platforms for the growth of light-emitting III-V compounds; ii) hard-masters for nano-imprint lithography of metal oxides (e.g. TiO2, SiO2, ZnO, Al2O3) deposited via sol-gel dip-coating (soft-NIL) and printed on arbitrary substrates, with tunable chemical and physical properties (e.g. composition, porosity, wettability). Methods and structures will be optimized towards their exploitation in two main domains of application: 1) photonic devices (e.g. anti-reflection coatings, colour-filters, random lasers, quantum emitters) and 2) micro-fluidic devices for bio/chemical sensing and water filtering. NARCISO holds the state-of-the-art in SSD and soft-NIL and is already at work in their theoretical comprehension their experimental implementation and practical exploitation. Now NARCISO will combine these techniques bringing them to the leading-edge of micro-and nanostructuring over ultra-large scales and with methods compatible with an industrial scale-up. The presence of the non-academic member Obducat Technologies is a strategic asset of the consortium as it is a major international actor in the nano-imprint lithography domain. It will provide the standard and needs for a realistic formulation of the relevant experimental methods and will demonstrate their implementation in a high-throughput industrial chain of production.";2592078,75;2588828,75;H2020-FETOPEN-2018-2019-2020-01;/RIA;CONSIGLIO NAZIONALE DELLE RICERCHE;IT;"UNIVERSITE DE LAUSANNE;UNIVERSITA DEGLI STUDI DI FIRENZE;UNIVERSITE D'AIX MARSEILLE;OBDUCAT TECHNOLOGIES AB;TECHNISCHE UNIVERSITAET DRESDEN";"CH;IT;FR;SE;DE";;1;0;0;1;0;0 221192;838335;Net4Society5;SIGNED;H2020-EU.3.6.;IBA-SC6-NCP-2018;H2020;National Contact Points (NCPs) Network of Societal Challenge 6 'Europe in a changing world – inclusive, innovative and reflective Societies' (SC6);2019-02-01;2020-08-31;;"Net4Society5 will be the transnational network of National Contact Points (NCPs) for Societal Challenge 6 (SC6) “Inclusive, innovative, and reflective societies” in Horizon 2020. NCPs are set up to guide researchers in their quest for securing EU funding. Net4Society5 will further develop the current Net4Society network of SC6 NCPs (former NCPs for Socio-economic Sciences and Humanities), which was first established in 2008 and includes currently around 90 SC6 NCPs from over 55 countries in Europe and beyond. Net4Society5 will ensure that all SC6 NCPs have the relevant knowledge and skills for their work and can offer professional, high-quality and tailor-made services to applicants. All nominated SC6 NCPs (also non-beneficiaries) will continue to have access to information and capacity building tools such as workshops, SC6 NCP Info sessions, trainings, webinars, factsheets or newsletters. Net4Society5 foresees targeted activities to support applicants in SC6, with a special focus on those countries that have been participating at low levels in the programme up to now. The project will facilitate interdisciplinary and international consortium building through the organisation of brokerage events, through a sector specific partner search service and through a research directory of SC6 key players. In addition, Net4Society5 will organise a regional Info day and proposal check event in a country that has been participating at low level in the programme up to now. To support the successful integration of Social Sciences and Humanities (SSH) in all parts of Horizon 2020, Net4Society5 will publish success stories and factsheets on “SSH integration”, as well as a document listing funding opportunities for SSH in all of Horizon 2020. Various promotional activities enhancing the visibility of Net4Society5 services and the SC6 in Horizon 2020 will underline these efforts.";500000;500000;H2020-IBA-SC6-NCP-2018;/CSA;DEUTSCHES ZENTRUM FUER LUFT - UND RAUMFAHRT EV;DE;"RANNSOKNAMIDSTOD ISLANDS;FUNDACION ESPANOLA PARA LA CIENCIA Y LA TECNOLOGIA;BELARUSIAN STATE UNIVERSITY;IDRYMA PROOTHISIS EREVNAS;AGENZIA PER LA PROMOZIONE DELLA RICERCA EUROPEA;TURKIYE BILIMSEL VE TEKNOLOJIK ARASTIRMA KURUMU;CENTRUM VEDECKO TECHNICKYCH INFORMACII SLOVENSKEJ REPUBLIKY;GIS-TRANSFERCENTER FOUNDATION;INSTYTUT PODSTAWOWYCH PROBLEMOW TECHNIKI POLSKIEJ AKADEMII NAUK;AGENCIJA ZA MOBILNOST I PROGRAME EUROPSKE UNIJE;RESEAU FRANCAIS DES INSTITUTS D'ETUDES AVANCEES;VEREIN EURESEARCH;OESTERREICHISCHE FORSCHUNGSFOERDERUNGSGESELLSCHAFT MBH;FUNDACAO PARA A CIENCIA E A TECNOLOGIA";"IS;ES;BY;CY;IT;TR;SK;BG;PL;HR;FR;CH;AT;PT";;1;0;0;1;0;0 218480;813467;EDIFY;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2018;H2020;European Doctorate in Indium Phosphide PIC Fabrication Technology;2018-10-01;2022-09-30;;"Photonic integration (PI) is a new standard for providing cost effective and high-performance miniaturized optical systems for a wide range of applications. However, higher adoption of photonic IC-based products and services across a wide range of verticals still calls for several optimizations namely at the level of active material for the lasers, decrease of the overall waveguide loss and development of better predictive performance methodologies implemented in the Process Design Kits (PDK). EDIFY will overcome this challenges by providing cutting-edge training to young researchers on the emerging field of integrated photonics and its translation into circuit fabrication and commercialization. EDIFY will train three ESRs at two world-leading European academic institutions and four industrial companies, thus forming a strong interdisciplinary network between industry and technical sciences to overcome specific barriers of the integrated photonics sector. Skilled in a multidisciplinary background (i.e. photonics fundamentals, circuit design and dedicated software and nanofabrication modalities) EDIFY ESRs will jointly contribute for significant improvements in the performance, power consumption and predictive methodologies of current PICs technologies with direct impact in: data communications, fibre-tothe- home, fibre sensors, gas sensing, medical diagnostics, metrology and consumer photonics. The availability of professionals combining the EDIFY ESRs skills will directly fuel emerging PIC-based innovation and ensure its exploitation by the photonic industry. Importantly, with these emerging opportunities unique career opportunities will arise for the professionals involved in this technological step change in Photonic ICs segment.";1003619,52;1003619,52;H2020-MSCA-ITN-2018;/MSCA-ITN-EID;UNIVERSIDAD DE VIGO;ES;SMART PHOTONICS BV;NL;;1;0;0;1;0;0 212137;770348;NEMESIS;SIGNED;"H2020-EU.3.6.1.1.;H2020-EU.3.6.2.";CO-CREATION-01-2017;H2020;Novel Educational Model Enabling Social Innovation Skills development;2017-10-01;2021-01-31;;NEMESIS designs, develops and tests an educational model for equipping students of primary and secondary education with Social Innovation Skills, values and tools. This process will enable students to become creative social thinkers, develop entrepreneurial mindsets, and become social change makers into a world where inequality, poverty and social exclusion are still quite evident. The NEMESIS model builds on a combination of innovative pedagogies and learning models, open technologies and participatory relations and processes. It also creates bridges between the learning communities and real world social innovation experiences by creating a European wide community of social innovation practitioners eager to interact with students, facilitating interdisciplinary and intergenerational learning. To foster its potential to scale and be adopted by educational institutions around Europe, the project develops a Social Innovation Open Learning Platform to grant access to the specific educational model and resources to all with emphasis on those from disadvantaged environments. This platform also facilitates the creation of a Community of Practice of teachers, school leaders and relevant stakeholders willing to break silos, engage in dialogue, drive organizational change and experience the value of the NEMESIS educational model. NEMESIS will be piloted in Greece, Spain, UK, France and Portugal engaging stakeholders into co-creation of educational resources, collective learning through the development of projects and digital storytelling as well as into online learning and knowledge sharing communities of peers. In that way, the project builds a contemporary educational model that will act as a catalyst in innovative skills based education in Europe that is expected to improve current teaching and learning practices and drive students’ passion for sustainable social change.;2237875;2132912,5;H2020-SC6-CO-CREATION-2017;/IA;FRIEDRICH-ALEXANDER-UNIVERSITAET ERLANGEN NUERNBERG;DE;"ASOCIACION CULTURAL COMENZEMOS EMPEZEMOS;U2D LONDON LIMITED;SOCIAL ENTERPRISE INTERNATIONAL LTD;AGRUPAMENTO DE ESCOLAS DA MAIA;HEALTHAPP SL;EUROPEAN SCHOOL HEADS ASSOCIATION;BOROUME SAVING FOOD SAVING LIVES;GAREFI IOANNA;STIMMULI FOR SOCIAL CHANGE;WILLOW TREE ACADEMY;PERIFEREIAKI DYETHINSI PROTOVATHMIAS KAI DEFTEROVATHMIAS EKPAIDEFSIS KENTRIKIS MAKEDONIAS;LES TETES DE L'ART;CIUDAD INDUSTRIAL DEL VALLE DEL NALON SA";"ES;UK;PT;NL;EL;FR";;1;0;0;1;0;0 220199;822166;Governance;SIGNED;"H2020-EU.3.6.3.;H2020-EU.3.6.1.";GOVERNANCE-14-2018;H2020;Democratic governance in a turbulent age;2018-12-01;2023-11-30;;"Democratic politics and governance in Europe are facing turbulent times. This not only affects the institutions of government, but the wider structures and processes that make democratic societies work. In order to respond to them, we require an understanding of the nature, causes and consequences of these challenges, as well as assessments of how governments, political parties, interest groups and other societal actors can effectively address them. With this proposal for a research programme on the topic of governance, NORFACE offers a timely investigation of the precise nature of the turbulence, but also how European states can negotiate it and develop strategies to enhance the quality of democratic politics and governance. The proposed programme will focus on themes derived from five critical challenges to democratic governance and the responses to them: inequality and redistribution, the evolving politics of threat, democratisation of information, shifting identities and representation, and the changing authority of institutions. Through collaborative cross-disciplinary research based on cross-national, historical and/or longitudinal comparison, the programme will develop theoretically ambitious and empirically founded insights to enrich the knowledge base upon which to build new institutions, policies and practices and reshape existing ones for a reflective, inclusive and innovative society. NORFACE (New Opportunities for Research Funding Agency Cooperation in Europe) is a collaborative partnership of national research funding agencies in the area of social and behavioural sciences. Since 2004, NORFACE has been committed to leading and developing opportunities for social scientists in Europe by developing thematic joint research programmes; building capacity for transnational and interdisciplinary research; advocating for the societal value of the social sciences; and sharing excellence in research management practices and procedures.";9090927;3000000;H2020-SC6-GOVERNANCE-2018;/ERA-NET-Cofund;NEDERLANDSE ORGANISATIE VOOR WETENSCHAPPELIJK ONDERZOEK;NL;"STYRELSEN FOR FORSKNING OG UDDANNELSE;FONDS ZUR FÖRDERUNG DER WISSENSCHAFTLICHEN FORSCHUNG;SIHTASUTUS EESTI TEADUSAGENTUUR;RANNSOKNAMIDSTOD ISLANDS;Lietuvos mokslo taryba;DEUTSCHE FORSCHUNGSGEMEINSCHAFT;VETENSKAPSRADET - SWEDISH RESEARCH COUNCIL;JAVNA AGENCIJA ZA RAZISKOVALNO DEJAVNOST REPUBLIKE SLOVENIJE;FORSKINGSRADET FOR HALSA ARBETSLIVOCH VALFARD;AKADEMIE VED CESKE REPUBLIKY;AGENCIA ESTATAL DE INVESTIGACION;SUOMEN AKATEMIA;NARODOWE CENTRUM NAUKI;UNITED KINGDOM RESEARCH AND INNOVATION;NORGES FORSKNINGSRAD;SCHWEIZERISCHER NATIONALFONDS ZUR FORDERUNG DER WISSENSCHAFTLICHEN FORSCHUNG;AN TUDARAS UM ARD OIDEACHAS;SERVICE PUBLIC FEDERAL DE PROGRAMMATION POLITIQUE SCIENTIFIQUE;FONDS NATIONAL DE LA RECHERCHE;AGENCE NATIONALE DE LA RECHERCHE;FONDS VOOR WETENSCHAPPELIJK ONDERZOEK-VLAANDEREN;FONDS NATIONAL DE LA RECHERCHE SCIENTIFIQUE;FUNDACAO PARA A CIENCIA E A TECNOLOGIA";"DK;AT;EE;IS;LT;DE;SE;SI;CZ;ES;FI;PL;UK;NO;CH;IE;BE;LU;FR;PT";;1;0;0;1;0;0 219701;824665;RECIPES;SIGNED;H2020-EU.5.g.;SwafS-18-2018;H2020;REconciling sCience, Innovation and Precaution through the Engagement of Stakeholders;2019-01-01;2021-12-31;;"RECIPES seeks to address the highly debated question as to how to protect health and safety of persons and the environment whilst promoting innovation. RECIPES is pioneering because of its a ground-breaking and interdisciplinary endeavour involving the integration of social and legal discipline and based on co-creation with policy-makers and other stakeholders. It aims to reconcile science, innovation and precaution to foster social awareness and responsibility in the EU in research and innovation by developing new empirically sound and theory informed institutional design and tools. It will build effective cooperation between science and society and link scientific excellence with social awareness and responsibility. In order to fully grasp the complexity and the controversies around the precautionary principle, RECIPES will examine the application of the precautionary principle in international treaties, EU level and five countries. It will also carry out eight case-studies, so as to understand and explain the potential differences in the application of the precautionary principle in the different cases, which reflects the particular context of the case and reasoning behind the decision to invoke the precautionary principle. RECIPES will develop new tools for the application of the precautionary principle taking into account the innovation principle. It will involve engagement of stakeholders in all stages of the research. It will moreover develop mechanisms for public involvement in research and innovation. It will develop scenarios for the future application of the precautionary principle and from there, it will co-create a new approach to the precautionary principle and new tolls to help policymakers and other stakeholders to assess risks and uncertainty and allow decisions to be made on a case-by-case basis, responding to the question how to responsibly decide on precaution and innovation.";1999831,25;1999831,25;H2020-SwafS-2018-1;/RIA;UNIVERSITEIT MAASTRICHT;NL;"KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW;APPLIED RESEARCH AND COMMUNICATIONS FUND;DIALOGIK GEMEINNUETZIGE GESELLSCHAFT FUER KOMMUNIKATIONS- UND KOOPERATIONSFORSCHUNG mbH;FONDEN TEKNOLOGIRADET;HUMBOLDT-UNIVERSITAET ZU BERLIN;CONOSCENZA E INNOVAZIONE SOCIETA ARESPONSABILITA LIMITATA SEMPLIFICATA;OESTERREICHISCHE AKADEMIE DER WISSENSCHAFTEN;INSTITUTE FOR ADVANCED SUSTAINABILITY STUDIES EV;UNIVERSITETET I BERGEN;ECOLOGIC INSTITUT gemeinnützige GmbH";"NL;BG;DE;DK;IT;AT;NO";;1;0;0;1;0;0 219144;825712;OBERON;SIGNED;H2020-EU.3.1.1.;SC1-BHC-27-2018;H2020;An integrative strategy of testing systems for identification of EDs related to metabolic disorders;2019-01-01;2023-12-31;;Exposure to chemical substances that can produce endocrine disrupting effects represents one of the most critical public health threats nowadays. In line with the regulatory framework implemented within the European Union to reduce the levels of endocrine disruptors (EDs) for consumers, new and effective methods for ED testing are needed. The OBERON project will build an integrated testing strategy (ITS) to detect EDs-related metabolic disorders by developing, improving and validating a battery of test systems. It will be based on the concept of an integrated approach for testing and assessment (IATA). OBERON will combine 1) experimental methods (in vitro e.g. on 2D and 3D human-derived cells and tissues, and in vivo i.e. in zebrafish at different stages), 2) high throughput omics technologies, 3) epidemiology and human biomonitoring studies and 4) advanced computational models (in silico and systems biology) on functional endpoints related to metabolism. Such interdisciplinary framework will help at deciphering EDs based on mechanistic understanding of toxicity by providing and making available more effective alternative test methods relevant for human health that are in line with regulatory needs. Data generated in OBERON will also allow the development of novel Adverse Outcome Pathways (AOPs). The assays will be pre-validated in order to select the test systems that will show acceptable performance in terms of relevance for the second step of the validation process, i.e. the inter-laboratory validation as ring tests. Therefore, the aim of the OBERON project is to support the OECD conceptual framework for testing and assessment of EDs by developing specific assays not covered by the current tests, and to propose an IATA approach for ED-related metabolic disorders detection, which will be submitted to the JRC and OECD community.;6745894,5;5978762,5;H2020-SC1-2018-Single-Stage-RTD;/RIA;INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE;FR;"Masarykova univerzita;ARISTOTELIO PANEPISTIMIO THESSALONIKIS;ISTITUTO DI RICERCHE FARMACOLOGICHE MARIO NEGRI;INSTITUT NATIONAL DE L ENVIRONNEMENT ET DES RISQUES INERIS;FUNDACION PRIVADA INSTITUTO DE SALUD GLOBAL BARCELONA;INSERM TRANSFERT SA;UNIVERSIDAD MIGUEL HERNANDEZ DE ELCHE;AGENCE NATIONALE DE LA SECURITE SANITAIRE DE L ALIMENTATION DE L ENVIRONNEMENT ET DU TRAVAIL;METABOLOMIC DISCOVERIES GMBH;BIOFYZIKALNI USTAV AKADEMIE VED CESKE REPUBLIKY";"CZ;EL;IT;FR;ES;DE";;1;0;0;1;0;0 220931;820047;THERA;SIGNED;H2020-EU.1.1.;ERC-2018-COG;H2020;Timing of Holocene volcanic eruptions and their radiative aerosol forcing;2019-03-01;2024-02-29;;"Volcanic eruptions play a dominant role in driving climate, in ways beyond the established short-term influence on surface air temperatures. In order to mitigate and adapt to the climate effects of future large volcanic eruptions we need to better quantify the risk of these eruptions including 1) the probability of their occurrence and 2) their expected climatic impact. The observational record of the timing of volcanic eruptions, their locations, magnitudes of sulphate aerosol injection is incomplete which limits our understanding of the sensitivity of the Earth system to volcanism and the vulnerability of social and economic systems to the climate impact of past and future eruptions. The primary goal of this proposal is to extract data on the timing, magnitudes and source locations of all major volcanic eruptions occurring during the Holocene (i.e., the past 12,000 years) to answer the questions: What is the likelihood of a stratospheric sulfur injection as large as that from the colossal eruption of Tambora in 1815 to occur somewhere on the globe within the next 100 years? What is the role of effusive eruptions on past, present and future climate? This will be achieved by employing novel, precisely dated, high-time resolution aerosol measurements from bipolar ice-core arrays. New tools will be used to constrain source parameters of the eruptions (location, plume injection height) that control their effects on climate. THERA will constrain recurrence rates for one of the largest global-scale natural hazards, while also assessing linkages between volcanic perturbations and key components of the climate systems (e.g., atmospheric circulation, droughts, ice-sheets and sea-level) through interdisciplinary case studies. As a final goal, THERA will generate global-scale, space-and-time resolved stratospheric aerosol properties for climate models to simulate the volcanic influence on Holocene climate evolution.";1978923;1978923;ERC-2018-COG;/ERC-COG;UNIVERSITAET BERN;CH;;;;1;0;0;1;0;0 217574;799791;DigRTEpi;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;New integrated system to automatically record impact of interictal epileptic activity on behavior, reactivity, and consciousness of epilepsy patients;2019-04-01;2022-03-31;;Behavior, reactivity and consciousness of epilepsy patients may be unpredictably impaired by seizures. For one important aspect in the daily lives of epilepsy patients, driving, international and national guidelines exist. These guidelines for the fitness to drive require worldwide a period of seizure freedom. In addition, a compatible electroencephalography (EEG) recording is required for vocational drivers in many countries and for all traffic participants in few countries including Switzerland. It’s about the occurrence of epileptiform EEG potentials in-between seizures that are not perceived by epilepsy patients and not visible to observers, called interictal epileptic activity (IEA). Detailed EEG compatibility specifications have however not been formulated. In an interdisciplinary approach with neurology, medical electronics engineering, behavioral neurosciences, and informatics, we aim at developing the first integrated system that automatically records the impact of IEA on behavior, reactivity, and consciousness in epilepsy patients, called DigRTEpi Test. This test should support physicians in their assessment of IEA effects on reactivity and thus provides objective and standardized support in the decision on EEG compatibility and the fitness to drive in clinical practice. The new system will circumvent digital latencies by computers and software, record patients’ effective reaction times and thus will open a new dimension of accuracy. A new open-source video-EEG synchronization and compatibility with various commercial EEG recording devices will grant user-friendliness. Patients will benefit from a better understanding of the impact of IEA on their daily activities of life because IEA effects can be made plausible to them by reaction time prolongations, and thus decisions on EEG compatibility may be better accepted. In future, we also work towards integrating the DigRTEpi Test into guidelines for the fitness to drive.;257860,8;257860,8;H2020-MSCA-IF-2017;/MSCA-IF-GF;JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN;DE;UNIVERSITAET BERN;CH;;1;0;0;1;0;0 215316;795091;ZEOCATALYST;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Development of Multifunctional Zeolites for the Amelioration of Biomass Catalysis by Measuring and Understanding Synergistic Effects of Catalytic Active Sites;2019-03-01;2021-02-28;;"Custom manufacturing of fine chemicals such as fuels, additives and plasticizers is a vital part of modern industrial chemistry. Increasing demand for the production of such chemicals necessitates the development of sustainable approaches. Biomass valorization is a potential solution to this problem; however, several challenges must be overcome to efficiently transform highly cross-linked biopolymers into desired chemicals. Notably, biocatalysts and heterogeneous catalysts offer promising efficiency for converting biomass-derived products in to small molecules. For such approaches to be successful, in particular when using heterogeneous catalysts, it is crucial to understand the local compositions, structures and synergistic effects between catalytic active sites on surfaces. Neglecting such factors during the biomass catalysis process is troublesome leading to reduced yields and undesired products. Here propose to develop a novel approach by combining zeolite post-synthesis modification with in situ and ex situ NMR spectroscopy techniques to gain a new molecular-level insight into zeolite-based biomass catalysis. We will accomplish this by modifying zeolites surfaces (via incorporating Zr, Sn, Zn and La heteroatoms into ZSM-5, USY and beta zeolite frameworks) using hydrothermal and chemical methods. The catalytic activity of zeolites will be tested for cascade conversions of sugar carbohydrates, lignin-derivatives and triglyceride-based compounds into valuable chemicals. The zeolite surfaces will be thoroughly characterized using electron microscopy, X-ray diffraction, BET isotherm measurements, 1D and 2D solid-state NMR techniques. This project is expected to create a significant leap forward in fundamental understanding and development of heterogeneous catalysts for biomass valorization. In addition, both experienced researcher and host will benefit from establishing interdisciplinary research and deliver research excellence to academia and industry.";173076;173076;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;UNIVERSITE DE LILLE;FR;;;;1;0;0;1;0;0 214224;799904;CAPSICE;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;CAPSizing ICE caps: identifying tipping points through global modelling;2019-02-28;2021-02-27;;"Ice caps have been major contributors to sea-level rise over the past decades and also in the coming century they are projected to further lose a substantial part of their volume, maintaining their position as one of the main sea-level rise contributors. One of the drawbacks of these projections, however, is that they are based on approaches that strongly simplify ice cap processes by relying on volume-area scaling methods or parameterisations derived from observations on mountain glaciers. Consequently, these projections fail to provide insights on feedback processes that can have an important impact on the future evolution of ice caps. Within this project, I want to implement GloCAP3D, the first global 3-D ice cap evolution model in which surface mass balance and ice dynamics are explicitly accounted for, in order to improve future projections of ice caps. Firstly, I will focus on calibrating GloCAP3D, which is a crucial step to ensure accurate future ice cap projections. For this, remote sensing products and other increasingly available datasets will be included. Secondly, I will assess the role of tipping points in the future evolution of ice caps and identify potential points-of-no-return, beyond which the loss of individual ice caps is irreversible. Particular focus will be on tipping points related to the surface mass balance - elevation feedback and on tipping points resulting from a potential strong reduction in the refreezing potential. The incorporation of ice dynamics will also allow to further quantify the mass loss through frontal calving, which can regionally be a major annual mass loss driver. Finally, through this novel interdisciplinary approach it will be possible to provide improved estimates on the future sea-level contribution from ice caps. Given project’s unique nature, its outcome is anticipated to be pivotal for a number of future works, including the upcoming Intergovernmental Panel on Climate Change Assessment Report.";165598,8;165598,8;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;TECHNISCHE UNIVERSITEIT DELFT;NL;;;;1;0;0;1;0;0 213964;793479;Family Myths;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Family Myths: Phraseology and Inherited Indo-European Thematic Structures in Greek Myth;2018-05-01;2020-04-30;;"My project examines thematic structures in Greek poetry of archaic and classical ages (8th–5th B.C.) in order (1) to collect and analyze words and phrases which characterize thematic structures of Greek mythological narratives; (2) to locate possible connections between mythological accounts and ancient rituals, elucidating how myths and rituals interact, and (3) to identify parallels in other branches of Indo-European (IE). Specifically, the reconstruction of IE thematic heritage is made to rely upon the linguistic comparison among words and phrases attested within mythological and ritual texts of Greek and its sister languages (Indo-Iranian, Anatolian, Italic, Germanic). As stated in previous literary criticism, classics “hide in the layers of memory disguised as the individual’s or the collective unconscious” and “persist as a background noise even when a present that is totally incompatible with them holds sway” (I. Calvino). My investigation, then, will try to cast light on the obscure genetic origins of texts, which had an extensive impact on artistic and intellectual categories of Western society. In particular, I will try to supply a refined methodology for the phraseological analysis. Simultaneously, through an interdisciplinary approach, my study will shed light on particulars of mythological stories, which are shared by two or more IE daughter languages, helping to sketch the chronological layers and distributional patterns of myths within the IE family tree. Therefore, my project perfectly fits into the research activity of the Research Centre “Roots of Europe” at Department of Nordic Studies and Linguistics in Copenhagen, which is concerned with the linguistic, cultural and ethnic prehistory of Europe. The training program and further activities promoted by the fellowship will provide me with an increased linguistic expertise, new management skills and an expanded research network.";200194,8;200194,8;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;KOBENHAVNS UNIVERSITET;DK;;;;1;0;0;1;0;0 211918;766972;NANOPHLOW;SIGNED;H2020-EU.1.2.1.;FETOPEN-01-2016-2017;H2020;TOWARDS NOVEL NANO-SCALE TECHNOLOGIES BASED ON PHORETIC FLOW EFFECTS;2018-02-01;2021-01-31;;"Most devices that transport bulk fluids make use of pressure gradients (`pumps’) or external forces (e.g. gravity powers hydro-electric turbines). Increasingly, modern technology is addressing problems where fluid transport takes place in sub-micron sized channels, or in pores. The physical laws of transport in such channels are qualitatively different from those that determine bulk flow; they are poorly understood and, importantly, barely exploited. The aim of the proposed research is to lay the basis for an entire novel technology where thermal gradients and concentration gradients along nano-sized channels are harnessed to drive devices that have no equivalent on the macroscopic scale. Such gradient-driven surface flows offer a huge scope for fundamental advances with very significant technological implications. We envisage breakthroughs in the area of energy extraction from salinity gradients (`blue energy’), ultra-filtration and desalination, and the development of novel, highly sensitive protein-separation devices. This new approach will surpass the intrinsic limitations of current technologies. The expected huge improvement in efficiency will be a game changer and will break the current barriers in the development of technologies such as e.g osmotic energy harvesting. All the applications share the same underlying science and can therefore be addressed by the proposal team. We will engage with industrial partners inside the team and with new partners that we will approach through our Knowledge Transfer Facilitator, to translate basic science into proofs-of-principle, pilot plants and, subsequently, full scale applications. The potential economic impact of phoretic technologies is difficult to over-estimate: the research is truly high-risk, high-yield. By targeting two diverse applications, we exploit the generic nature of the underlying science. The quality and interdisciplinary nature of the team mitigates the risk of failure.";3299670,01;3299670;H2020-FETOPEN-1-2016-2017;/RIA;UNIVERSITAT DE BARCELONA;ES;"THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;SWEETCH ENERGY;FLUIDIC ANALYTICS LIMITED;UNIVERSITEIT UTRECHT;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS";"UK;FR;NL";;1;0;0;1;0;0 220832;814066;MARSoluT;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2018;H2020;Managed Aquifer Recharge Solutions Training Network;2019-03-01;2023-02-28;;"Managed Aquifer Recharge (MAR) – storing water in aquifers during times of excess – is a key strategy to enrich groundwater resources in water scarce regions by providing intermediate storage, addressing the typical mismatch between water demand and availability. It can help to mitigate the effects of climate change, and to support water-related environmental services. MAR is, however, characterized by complex interaction of physical, biological and hydrochemical processes influencing water quality and the sustainability of infiltration rates. Individual processes are in principal known, but there is a significant knowledge gap on how they are linked and affect each other. An in-depth understanding of their interplay can lead to MAR systems tailored for best performance in terms of water storage, water polishing goals, infiltration rates, economic viability, and adaptation to climatic change. MARSoluT addresses this knowledge gap by a collaborative effort in a multi-disciplinary team. Activities are organized around the existing field sites of previous EU FP7 project MARSOL that are already highly characterised and instrumented to allow further in-depth studies and experimental approaches. This will lead to new insights into the complex and coupled processes at MAR sites and will help to optimize MAR design and operation, and thereby minimizing risk of MAR failure. Excellence in research and technological innovation are ensured by involving partners from renown research organizations as well as SMEs and industry partners with a strong background in the water sector. MARSoluT ESRs will get hands-on experience at various MAR sites while tackling specific MAR-related research topics in an interdisciplinary team. MARSoluT ESRs will become experts on the tailored planning of MAR systems making them attractive for employers from research, industry, and regulatory agencies which are eager to implement MAR into sound and safe Integrated Water Resources Management concepts.";2992494,24;2992494,24;H2020-MSCA-ITN-2018;/MSCA-ITN-ETN;TECHNISCHE UNIVERSITAT DARMSTADT;DE;"NATIONAL TECHNICAL UNIVERSITY OF ATHENS - NTUA;THE AGRICULTURAL RESEARCH ORGANISATION OF ISRAEL - THE VOLCANI CENTRE;HELMHOLTZ-ZENTRUM FUR UMWELTFORSCHUNG GMBH - UFZ;ENERGY AND WATER AGENCY;LABORATORIO NACIONAL DE ENGENHARIA CIVIL;EMPRESA DE TRANSFORMACION AGRARIA SA;SCUOLA SUPERIORE DI STUDI UNIVERSITARI E DI PERFEZIONAMENTO SANT'ANNA;UNIVERSITAT POLITECNICA DE CATALUNYA;UNIVERSIDADE DO ALGARVE";"EL;IL;DE;MT;PT;ES;IT";;1;0;0;1;0;0 220879;818717;V-ECHO;SIGNED;H2020-EU.1.1.;ERC-2018-COG;H2020;Revealing hidden volcanic triggers for global environmental change events in Earth’s geological past using mercury (Hg);2019-06-01;2024-05-31;;"Rapid global change events such as mass extinctions punctuate Earth’s geological history. These have driven life’s evolution, shaping the world today. However, the exact processes that trigger or modulate them remain enigmatic. Episodes of large-scale volcanism, namely large igneous provinces (LIPs), are a prime contender. A major obstacle to unravelling the role of LIPs in rapid global change has been lack of a direct/unique proxy for volcanism in the sediments that record events. Without one, determining LIP occurrence and exact temporal relations is challenging, especially where the rock record of LIPs is incomplete. Recent studies have revealed the huge promise of mercury (Hg) as a marker of large-scale volcanism. However, while Hg-record acquisition is gaining pace, we still lack the vital process understanding of the proxy needed to realize its full potential. V-ECHO will test the overarching hypothesis: widespread mercury ‘spikes’ in the geological record are definitive evidence of LIP volcanism even in the absence of coeval lavas. V-ECHO will take an integrated and interdisciplinary approach to develop a process understanding of LIP perturbations to the global Hg cycle and how these translate into sedimentary records. It will address key questions on Hg sources (emission from magmas or thermal metamorphism of intruded rocks) and sinks (deposition pathways and sedimentary preservation). It will combine new measurements with novel experimental techniques and explore key differences in the global Hg cycle deep in Earth’s past. V-ECHO will test whether we can ‘sniff out’ the sedimentary echoes of lost LIPs, especially in the Palaeozoic and Neoproterozoic where the LIP record becomes ever sparser. It will explore proposed volcanic triggers for major Earth change events (e.g., oceanic anoxic events, ‘snowball Earths’) in unprecedented ways. V-ECHO promises a step-change in understanding of environmental impacts of LIP volcanism throughout Earth history.";1999599;1999599;ERC-2018-COG;/ERC-COG;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;UK;"THE UNIVERSITY OF EXETER;ROYAL HOLLOWAY AND BEDFORD NEW COLLEGE";UK;;1;0;0;1;0;0 210269;743544;H-E Interactions;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Increasingly Anthropogenic Landscapes and the Evolution of Plant-Food Production: Human - Environment Interactions during the Final Pleistocene and Early Holocene in the Levant.;2017-09-01;2020-04-28;;H-E Interactions will investigate how increasingly anthropogenic wetland landscapes and the reliable resources therein influenced the evolution of plant-food production and the origins of agriculture through the Final Pleistocene into the Early Holocene (ca.23-8 ka cal. BP). It will consider how earlier human-environment interactions shaped this key transition, integrating the latest theoretical Human Niche Construction (HNC) perspectives with environmental archaeology to investigate 5 well-excavated wetland oriented archaeological sites in the S. Levant. It will employ an interdisciplinary, combination of microbotanical approaches, (phytolith, starch and microcharcoal analyses) and geoarchaeology, in particular micromorphology, to investigate the on- and off-site contexts of a temporally broad set of sites to provide long-term, direct evidence of ancient plant-use. To achieve this, training in geoarchaeology, GIS and multivariate statistical skills will facilitate the production, management and interpretation of the large environmental dataset. As well as providing direct evidence of plant-use and environment from a critical H-E threshold, H-E Interactions is the first study in the region to directly examine how HNC practices impacted the origins of agriculture. So far, the origin of agriculture has been largely understood as a consequence of human reactions to environmental push & pull factors. This project presents an alternative approach and takes the view that increased use of ‘low-ranked’ resources may reflect deliberate human modification, management and/or food processing innovation, increasing the relative abundance and ease of acquisition of ‘low-ranked’ resources, resulting in ‘upward mobility’ of that resource. HNC provides a new way to consider changing plant resource selection in the Levant and the wider cultural and environmental implications, which may have impacted the rise of increasingly sedentary lifestyles and the origins of agriculture.;195454,8;195454,8;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;UK;;;;1;0;0;1;0;0 206775;734834;INFUSION;SIGNED;H2020-EU.1.3.3.;MSCA-RISE-2016;H2020;Engineering optoelectronic INterfaces: a global action intersecting FUndamental conceptS and technology implementatION of self-organized organic materials;2017-01-01;2020-12-31;;Investing in energy efficiency and saving is crucial to support energy accessibility and environmental protection, and it is the world’s best interest to share and implement forms of energy efficiency. This implies a stronger and effective transnational policy to promote and disseminate know-how about new technologies both at the market and R&D level. In this respect, development of projects centered on energy efficient technologies based on nanostructured organic materials certainly is a strategic field. The progresses in mastering organic matter by self-assembly and self-organization to form ordered soft-materials revolutionized the field opening new frontiers for both fundamental and applied research. However the route towards organic materials for application at the industrial scale is restricted by difficulties in the control and manipulation of the structural organization at the molecular level and its manifestation at higher scales. Motivated by the potential for significant energy savings, the INFUSION project aims to create a strongly interdisciplinary and inter-sectorial environment in which the principles of self-organization are poured from the Academia into the private sector and vice-versa to create new paradigms to engineer electrochromic devices. Through a detailed plan of 83 secondments, the project aims at cross-fertilize the electrochromic technology joining specific expertise to realize a bottom-up approach toward the design, preparation and characterization of self-organized organic materials (chromophores, CNSs, polymers...) at different interfaces (ITO, graphene) and exhibiting superior performances (optical, durability…). For the transfer of knowledge, the project combines the multidisciplinary expertise of 6 universities, 1 research institute, and 3 companies representing 4 EU and 2 TC countries (Pakistan and Argentina) in the field of organic chemistry, photochemistry, surface science, polymer and materials science, and device engineering.;1237500;1237500;H2020-MSCA-RISE-2016;/MSCA-RISE;UNIVERSITA DEGLI STUDI DI TRIESTE;IT;"MEDITEKNOLOGY SRL;CONSIGLIO NAZIONALE DELLE RICERCHE;A.P.E. RESEARCH SRL;YD YNVISIBLE SA;NOVA ID FCT - ASSOCIACAO PARA A INOVACAO E DESENVOLVIMENTO DA FCT;UNIVERSITE DE NAMUR ASBL;CARDIFF UNIVERSITY";"IT;PT;BE;UK";;1;0;0;1;0;0 202905;704903;BAC-STAR;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Bacterial Adhesion Control through Surface TArgeted Regulation;2017-09-01;2019-08-31;;"Fundamental investigations of bacterial adhesion will create the knowledge base to advance surface engineering approaches. Directed mutagenesis of adhesin genes in several oral pathogens will be used to create a library of knockout strains. Recombinant adhesins will also be over-expressed in E.coli. Assays will be developed to test the interaction of the resulting strains (wild-type, knockouts, over-expressing E.coli clones) with a range of materials, covering the entire spectrum of surface properties with defined roughness, hydrophobicity, porosity, charge and composition. Adhesion kinetics will be monitored in real time, using flow cells to mimic the shear stress and nutrient exchange on implants in vivo. This will complement plate-based fluorescence adhesion assays, western blotting, immunofluorescence microscopy, and ELISAs. Adhesion trends will be tested with targeted surface modifications in pure and mixed culture, creating a feedback-loop for assay improvement with gradually specialised surface functionalization. The ultimate goal is to develop surfaces that promote the adhesion of host tissue, such as human osteoblast cells or gingival cells, whilst still preventing pathogen adhesion. Understanding the fundamental interactions of bacteria with surfaces facilitates the transferability of the results from this project to a variety of further applications (e.g. adhesion of electrogens to microbial fuel cell electrodes; antifouling surfaces etc.). My proposal therefore has the potential to be high impact research, and generates the framework for future interdisciplinary projects.";208400,4;208400,4;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;UNIVERSITETET I OSLO;NO;;;;1;0;0;1;0;0 202906;704912;FLUORODRUGS;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Smart Theranostic Agents for the Tumour Microenvironment;2017-01-01;2018-12-31;;FLUORODRUGS is a highly interdisciplinary project encompassing the design, synthesis and biological validation of novel smart chemical agents for highly sensitive diagnosis and specific treatment of cancer. I will prepare novel drug-fluorophores conjugates by combining macrophage-specific fluorophores with cytotoxic drugs using smart cleavable linkers. The activation of these smart agents in the tumour microenvironment will allow to not only to visualise in real-time but also to selectively ablate tumour-associated macrophages, which are essential for cancer progression. Further derivatization of the agents with specific ligands (i.e. chemokine CCL2) will yield probes for specific subpopulations of macrophages (i.e. CCR2\ macrophages) that are critical in tumour metastasis. This strategy will minimise two of the major limitations of conventional cancer therapies: 1) drug resistance from cancer cells, and 2) toxic side effects derived from low cell specificity. Notably, the visualisation of immune cells in the tumour microenvironment will allow to monitor cancer progression in real-time and to run profiling studies to discover new biomarkers for cancer therapy. Initial in vitro studies to confirm the activity and selectivity of FLUORODRUGS will be performed in bone marrow-derived macrophages. Further, relevant mouse cancer models will be used to validate the theranostic agents in vivo. FLUORODRUGS will involve multidisciplinary training in biology, spectroscopy, pharmacology and imaging, and will render a unique generation of smart chemical tools to enhance diagnosis and treatment of cancer. This project will open a whole range of opportunities for my future career development in cancer biology and medicinal chemistry.;195454,8;195454,8;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;THE UNIVERSITY OF EDINBURGH;UK;;;;1;0;0;1;0;0 196950;664732;nuClock;SIGNED;H2020-EU.1.2.1.;FETOPEN-RIA-2014-2015;H2020;Towards a nuclear clock with Thorium-229;2015-06-01;2019-05-31;;"Atomic clocks are the backbone of our modern communication and navigation technology, e.g. through the global positioning system (GPS). Improving these clocks will open up exciting new applications in geodesy, fleet tracking, autonomous vehicles, augmented reality and shed light on some of the most fundamental questions in research. Today’s best atomic clocks lose only 1 second in 30 billion years, making them the most precise measurement devices ever built. However, such clocks are extremely delicate and susceptible to external perturbations; they can only be operated in specialized laboratories. We propose to develop a novel type of clock, based on a unique nuclear transition in Thorium-229. This nuclear clock will be fundamentally different from existing atomic clocks, which are based on transitions in the electron shell. It will be largely inert to perturbations, simpler by design, and holds the potential to outperform existing atomic clocks in terms of precision. So far, progress towards an application of the Thorium nuclear transition has been hampered by the extreme technological challenges related to the scarcity of 229Th, insufficient detector resolution, and exotic lasers frequencies. Suitable technology is only becoming available just now. Furthermore, this research demands supreme expertise in a variety of fields, encompassing nuclear and atomic physics, quantum optics, metrology, as well as detector- and laser technology. Our interdisciplinary consortium is assembled to precisely match these requirements, joining for the first time Europe’s leading research groups in the respective fields. The work will focus on two objectives; (i) finding clear evidence of the transition and measuring its frequency, and (ii) developing all key components required for operation of a nuclear clock. We are certain that next-generation satellite-based navigation technology and other precision timing applications will greatly benefit from more precise and robust clocks.";3970327,5;3970327,5;H2020-FETOPEN-2014-2015-RIA;/RIA;TECHNISCHE UNIVERSITAET WIEN;AT;"LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN;PHYSIKALISCH-TECHNISCHE BUNDESANSTALT;JYVASKYLAN YLIOPISTO;RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;TOPTICA PHOTONICS AG";"DE;FI";;1;0;0;1;0;0 214187;797603;Peripheality;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Exploring the function of peripheral vision in humans using virtual reality;2018-10-02;2020-10-01;;'The aim of this project is to determine the functional significance of the peripheral visual field for human perception and its interaction with the motor system. While it is well established that central vision serves to resolve the fine details of the visual world and the objects in it, the reduced spatial resolution in the peripheral part of our visual field suggests that peripheral vision may have a very different role. In this project we will use an innovative combination of Virtual Reality (VR) with physiological recordings and computational modelling to examine the hypothesis that the peripheral visual field acts as a change detection mechanism. Specifically, under conditions resembling those encountered in everyday life, we will explore the presence of serial dependency (SD) effects, i.e., the integration of past with current information during visual processing. These experiments will provide the first evidence that SD strategies are employed during everyday activities in complex environments in daily life, while the nature of the SD effects (i.e. positive vs. negative) will allow us to deduce differences in the functions of the central and peripheral visual system. Importantly, the experiments will also allow us to assess whether peripheral vision is involved in a multisensory and hypersensitive 'alarm system', an idea that has recently been proposed in the literature. Finally, by employing computational modelling methods we will attempt to provide a comprehensive theoretical account for experimental findings. Overall, this interdisciplinary project is expected to provide important insight into the basic mechanisms of human vision that are responsible for maintaining the equilibrium between visual stability and change detection over the whole visual field.';151648,8;151648,8;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;UNIVERSITY OF CYPRUS;CY;;;;1;0;0;1;0;0 211802;740696;SSID;SIGNED;H2020-EU.1.1.;ERC-2016-ADG;H2020;Soundscape Indices;2018-03-01;2023-02-28;;Eighty million EU citizens are suffering from excessive environmental noise and billions of euros are being spent on noise control, under the EU Directive on Environmental Noise. Unfortunately, the conventional approach, i.e. reduction of ‘sound level’, simply does not deliver the required improvements in quality of life. The growing field of ‘soundscape studies’ is addressing this gap by considering sound environment as perceived, in context, with an interdisciplinary approach. However, soundscapes are hugely complex and measuring them as a basis for environmental design requires a step change to the discipline. This research aims to achieve a ground-breaking development through the establishment of ‘soundscape indices’ (SSID), adequately reflecting levels of human comfort, the impact of which will be reminiscent of that of the Decibel scale created by Bell Systems a century ago. This will provide the underpinning science for soundscape in the field of built environment, with wider intellectual goals of moving from noise control to soundscape creation. Key objectives, as coherent steps for achieving the main aim, are: (1) To characterise soundscapes, by capturing soundscapes and establishing a comprehensive database, which will be a cornerstone for the proposed analysis, and an invaluable resource for scientists for years to come. (2) To determine key factors and their influence on soundscape quality based on the database, by conducting laboratory psychological evaluation, physical/psychoacoustic factors analysis, and more importantly, to research at a physiological/biological level, including the use of functional magnetic resonance imaging. (3) To develop, test and validate the soundscape indices, through analysing the influences by various factors, using a number of inter- & trans-disciplinary approaches. (4) To demonstrate the applicability of the soundscape indices in practice, by establishing frameworks for soundscape prediction, design, and standardisation.;2492201;2492201;ERC-2016-ADG;/ERC-ADG;UNIVERSITY COLLEGE LONDON;UK;THE UNIVERSITY OF SHEFFIELD;UK;;1;0;0;1;0;0 207398;715872;NANOINFER;SIGNED;H2020-EU.1.1.;ERC-2016-STG;H2020;Intelligent Memories that Perform Inference with the Physics of Nanodevices;2017-03-01;2022-02-28;;Cognitive tasks are increasingly necessary in modern electronics. The energy efficiency of associated algorithms, which rely on abundant stored parameters, is severely limited by the separation of computation and memory elements in conventional computers. In NANOINFER, I will directly address this challenge by developing intelligent memory chips that natively perform both memory and computing functions, using CMOS and emerging nanodevices. These chips will perform modern Bayesian inference algorithms, which allow cognitive-type reasoning. The project includes theoretical investigations as well as intelligent memory chip designs, which will be supported by proof-of-concept experimental demonstrations. The proposed architectures, based on spintronic and memristive memories, will maximize energy efficiency by leveraging the complex physics of these emerging devices for inference operations and the storage of model parameters, and by minimizing exchanges between computation units and memory. Inference will be performed using sampling algorithms that allow tackling difficult problems and are robust to nanodevice imperfections. The inference circuits will be composed of digital CMOS logic as well as spiking neurons circuits. Two standard Bayesian approaches will be employed to enable learning, permitting highly adaptive systems. Preliminary results on a system that performs na?ve Bayesian inference have validated this concept and its use with novel memory technologies. NANOINFER will resolve critical interdisciplinary challenges to permit intelligent memories to perform non-na?ve tasks, ensuring a correspondence between device physics and Bayesian concepts while maintaining a fusion between computation and memory. This project will deepen our understanding of novel memory technologies and develop a toolbox for creating intelligent memory chips. These will allow smart devices to perform cognitive/sensory-motor tasks at low energy without requiring large computing machines.;1499609;1499609;ERC-2016-STG;/ERC-STG;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FR;;;;1;0;0;1;0;0 207063;734736;VirFree;SIGNED;H2020-EU.1.3.3.;MSCA-RISE-2016;H2020;Virus free Fruit Nurseries;2017-01-01;2020-12-31;;Fruit trees and grapevine are propagated vegetatively and are often grafted. As a result they suffer from a high number of pathogens such as viruses and viroids, a number of which are causing severe yield losses and reduce the productive life of the affected plants. As these pathogens cannot be controlled by the application of chemicals, the most efficient way to combat them is the production and commercialization of high quality pathogen-tested propagative material. Nevertheless, this procedure is not simple and both academia and private sectors are working towards its improvement. In this direction was built the herein interdisciplinary proposal which brings together academia and private companies to collaborate through their expertise on the following objectives: 1) to identify new viral and viroid strains or species affecting fruit trees and grapevine, 2) to optimise existing and develop novel detection methods and 3) to improve propagation and sanitation methods for producing high quality (virus-tested) plant material of fruit trees and grapevine. In this project diagnostic tools that are currently used in certification programs will be combined with cutting edge technologies such as NGS and Nanobodies. The project has eight academic partners within the EU and associated countries, three within Third Countries and five non-academic partners. The knowledge obtained will be shared among the partners of the proposal and further disseminated to academic institutions, nurseries and other private sectors. Most importantly training of a new generation of researchers will be done in close contact to the needs of both industrial and academic sectors. In conclusion, the results of this proposal will enrich the knowledge on viruses/viroids associated with different diseases, improve the sensitivity of their detection methods, lead to new detection products and further contribute to the improvement of the disseminated propagative material of fruit trees and grapevine.;787500;630000;H2020-MSCA-RISE-2016;/MSCA-RISE;ARISTOTELIO PANEPISTIMIO THESSALONIKIS;EL;"UNIVERSITA DEGLI STUDI DELLA BASILICATA;BIOREBA AG;BETA FIDAN DOKU KULTURU ISLAH ARGEZIRAAT TARIM SULAMA HAYVANCILIK GIDA TURIZM INSAAT SANAYI TICARET LIMITED SIRKETI;FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS;XILOGIANNIS BROSS UN.CO;CONSIGLIO NAZIONALE DELLE RICERCHE;MUSTAFA KEMAL UNIVERSITY;AGRITEST SRL;INSTITUTO VALENCIANO DE INVESTIGACIONES AGRARIAS;TEKIRDAG NAMIK KEMAL UNIVERSITESI;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;LIFESEQUENCING SL";"IT;CH;TR;EL;ES;FR";;1;0;0;1;0;0 205752;706102;BREADforALL;CLOSED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;"IMPROVING GLUTEN-FREE FLOURS FUNCTIONALITY BY MW TREATMENTS; A TOOL FOR HIGH QUALITY OF GLUTEN-FREE BAKERY (PHYSICAL, SENSORIAL AND NUTRITIONAL)";2016-09-01;2018-08-31;;"Food safety, natural foods with clean labels, process intensification and green technology combination is an attractive research idea for the European Community being in line with the 'Health, Demographic Change and Wellbeing', 'Secure, clean and efficient energy' and “Biotechnology foresight identifying gaps and high-value opportunities for the EU industry” initiatives. BREADforALL project responds to this challenge using gluten-free (GF), nutritious, raw materials and clean, efficient technology to develop food products suitable for celiac disease patients, which moreover, represent both a social necessity and market opportunity. Celiac disease (permanent intolerance of gluten) is one of most common human genetic disorders nowadays with an increasing prevalence of 1-2%. The main problem is lack of high quality food, free of proteins triggering allergy and the target group of GF products is currently expanding to adhere e.g. people looking for non allergenic ingredients. The technological solutions adopted so far are mainly focused on hydrocolloids usage, substances that often result in crumb problems and significantly raise the prices. BREADforALL focuses on alteration of existing structures of protein and starch network for modulating the functionality of GF raw materials. Project aims 1) to investigate the impact of thermal treatment (green technology) assisted with microwave radiation (effective systems for energy saving) on structural, functional and physicochemical properties of GF flours (teff and buckwheat) and 2) to study the feasibility of treated flours to improve technological functionality of GF breadmaking matrices and physical and nutritional quality of bakery. The satisfactory implementation of BREADforALL project will fill the gap between multidisciplinary fields of food sciences and engineering establishing interdisciplinary scenario connecting microwave technology, flour physical modification and gluten-free baking technology.";170121,6;170121,6;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;UNIVERSIDAD DE VALLADOLID;ES;;;;1;0;0;1;0;0 204907;701737;SNAPTRACE;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Fishing in the dark: unravelling the global trade and traceability of the ‘snappers’;2016-07-04;2018-07-03;;"Despite the precarious state of the world’s marine ecosystems, it is now widely acknowledged that ‘where there is a sea, there are pirates’. Indeed, today’s alarming rates of illegal fishing and market fraud are of the most immediate threats to global fish stocks, creating unfair competition, impeding consumer choice and ultimately undermining efforts towards sustainable management. As such, it has become increasingly clear that seafood traceability is not a luxury; it is a true necessity in a world where growing human populations are placing immense pressure on the remaining oceanic resources. In the present application, a project is proposed that will significantly enhance our understanding of the intricacies of global seafood trade and pave the way forward for more transparent, traceable and sustainable seafood markets, using one of the world’s most highly-prized, yet misunderstood, groups of fishes as a model: the snappers, family Lutjanidae. In order to achieve this ambitious overarching goal, a multidisciplinary approach and state-of-the-art molecular techniques will be employed to systematically address the project’s three key objectives: 1) to use international trade data to unravel the drivers and dynamics of global snapper supply and demand; 2) to harness the power of DNA barcoding to evaluate the species sold as ‘snapper’ on world markets, and 3) to test the ability of cutting-edge genomic methods to trace premium snapper products back to their population / stock of origin. SNAPTRACE will be the foremost study to combine these core approaches in a truly global fashion, thus meeting the long standing demand for more pronounced interdisciplinary integration to tackle the complexities associated with the seafood supply chain. In its entirety, the outcomes of this project will prove both relevant and timely, initiating an evidence-based management of snapper resources, which at the moment remains extremely difficult to implement based on current insights.";183454,8;183454,8;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;THE UNIVERSITY OF SALFORD;UK;;;;1;0;0;1;0;0 200024;692976;FEUTURE;SIGNED;H2020-EU.3.6.;INT-09-2015;H2020;The Future of EU-Turkey Relations. Mapping Dynamics and Testing Scenarios;2016-04-01;2019-03-31;;"The EU and Turkey face mounting challenges both in relation to one another and internationally. The EU is confronted with an economic crisis which is likely to make differentiation a growing phenomenon. Turkey faces polarisation between different political forces, the state and civil society. The neighbourhood is unravelling to the east and south and a power shift is under way at global level. This questions the regional roles of Turkey and the EU. Accordingly, FEUTURE – a consortium of 13 experienced universities and think tanks from the EU, Turkey and the neighbourhood – aims to: (1) map the dynamics of EU-Turkey relations as to underlying narratives and thematic drivers; (2) substantiate most likely future scenario(s) and assess its implications; (3) draw policy recommendations. FEUTURE provides excellence and pursues an ambitious, inspiring and innovative programme in a three-phased structure of elaboration, exploration and extrapolation. It applies an inter-temporal, interdisciplinary and international approach by analysing drivers within six thematic dimensions (politics, security, economics, energy, migration, identity) and across four levels of analysis (EU, Turkey, neighbourhood, global). Phases 1 and 2 culminate in an extrapolation phase in which FEUTURE integrates new knowledge and tests the implications of 3 ideal-type future scenarios for EU-Turkey relations: conflict, cooperation and convergence. We engage in a trans-disciplinary exchange within an elite survey and with the knowledge-user community from the four levels of analysis exploiting the full range of virtual and social media as well as traditional means. FEUTURE’s work plan guarantees coherence of its research approach by streamlining work in one conceptual, one synthesis, two organisational and six thematic work packages. Joint WP meetings and three FEUTURE conferences assure intensive horizontal exchange. FEUTURE will achieve academic, practical and structural impact beyond the project.";2500895,63;2497984,5;H2020-INT-SOCIETY-2015;/RIA;UNIVERSITAET ZU KOELN;DE;"CRRC GEORGIA NON-ENTREPRENEURIAL (NON-COMMERCIAL;ISTANBUL BILGI UNIVERSITESI;MIDDLE EAST RESEARCH INSTITUTE;ISTITUTO AFFARI INTERNAZIONALI;DANSK INSTITUT FOR INTERNATIONALE STUDIER;KOC UNIVERSITY;Trans European Policy Studies Association;SABANCI UNIVERSITESI;Elliniko Idryma Evropaikis kai Exoterikis Politikis (HELLENIC FOUNDATION FOR EUROPEAN AND FOREIGN POLICY);CENTRE INTERNATIONAL DE FORMATION EUROPEENNE;CENTRE FOR INTERNATIONAL INFORMATION AND DOCUMENTATION IN BARCELONA;EKONOMI VE DIS POLITIKA ARASTIRMALAR MERKEZI DERNEGI - EDAM;THE AMERICAN UNIVERSITY IN CAIRO;MIDDLE EAST TECHNICAL UNIVERSITY";"GE;TR;IQ;IT;DK;BE;EL;FR;ES;EG";;1;0;0;1;0;0 200961;701636;HARA;CLOSED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Human-Animal Relationships in Archaeology: World Views of Hunter-gatherers in NorthernEurope;2016-09-01;2018-08-31;;Human-Animal Relationships in Archaeology: World Views of Hunter-gatherers in Northern Europe (HARA) will provide important new perspectives on human interactions with animals in Northern Europe in the ethnographic present and the archaeological past. This will include innovative analysis of ethnographic materials from NE Russia and archaeological materials from the Baltic, including Europe’s largest Stone Age burial ground (350 graves), Zvejnieki in Latvia. HARA will focus on how animal remains, especially artefacts manufactured on animal remains, and animal iconography reflect human-animal relations. With the aim to develop new perspectives on human-animal relationships among hunter-gatherers in Northern Europe the project will utilise innovative analogies and theoretical frameworks derived from ethnographic analysis and new experimental archaeological approaches to artefacts manufactured from animal remains. The case studies will allow an assessment of changes in human-animal relationships during the introduction of domestic animals: a process which is widely considered to have been transformative of human society and human understandings of animals and has been a significant focus for research. The academic impact of this multidisciplinary project is therefore substantial. The applicant will move from her current position with the Institute of Ethnology and Folklore Research, Zagreb,Croatia to School of Archaeology, University College Dublin, Ireland. She will receive training in experimental archaeology and animal osteoarchaeology, the archaeology of hunter-gatherers, and in teaching archaeology as well as a formal introduction to the management and delivery of research projects. Completion of this project will allow the applicant to develop into a position of professional maturity with a specific and unique interdisciplinary set of skills and will be able to pursue an international academic research and teaching career in the field of human-animal studies.;187866;187866;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN;IE;;;;1;0;0;1;0;0 201307;705249;RICC;CLOSED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;The Application of Advanced Raman Spectroscopies to the Quantitative Analysis of Industrial Chromatography Columns;2016-10-01;2018-09-30;;"Dr. Kevin Buckley (KB) was awarded his PhD from University College London (UCL) in 2011. At UCL he had worked to develop Raman spectroscopy as a tool for bone-disease diagnosis and he subsequently took a position as a Laser Spectroscopy Scientist, at the Rutherford Appleton Lab (RAL) in Oxfordshire, England, to continue this work. After leaving RAL, KB moved to the University of British Columbia (UBC) in Vancouver, Canada. At UBC he worked to develop a Raman spectroscopy-based instrument for detecting chemical changes in (donated) human red blood cells as they age in plastic blood-bags. He has recently (Aug 2015) returned to his home country of Ireland and the primary aim of the proposed Marie Sk³odowska-Curie Fellowship is to reintegrate him with the research community there. The primary scientific objectives of the fellowship to develop novel analytical methods based on Spatially Offset Raman Spectroscopy (SORS) for applications in biopharmaceutical manufacturing. It is proposed that this interdisciplinary research take place under the supervision of Dr. Alan Ryder (AR) in the Nanoscale Biophotonics Lab (NBL) at the National University of Ireland, Galway. The combination of KB’s SORS expertise with AR’s biopharma expertise has the potential to deliver innovative science; KB is one of the few researchers in the world who has years of experience with SORS of complex materials (he trained under the inventor of SORS, Prof. P. Matousek FRSC, at RAL) and AR is an international leader in the development of quantitative analytical methods for biopharmaceutical manufacturing processes. In addition to scientific objectives, the fellowship programme has been designed to develop KB’s career and enhance his ability as a scientist. He will be provided with opportunities to develop academic teaching skills and will prepare a specific career development strategy. AR will also mentor KB as he prepares post-fellowship grant proposals and begins his independent academic career.";175866;175866;H2020-MSCA-IF-2015;/MSCA-IF-EF-RI;NATIONAL UNIVERSITY OF IRELAND GALWAY;IE;;;;1;0;0;1;0;0 201214;704127;HEGNAT;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-GF;H2020;Naturalism in German Classical Philosophy: Nature, Recognition and Freedom in the Hegelian Theory of Social Interaction and Cooperation;2016-09-01;2019-08-31;;Hegel's theory of social interaction, recognition and freedom supplies us with a very perspicuous conception of cooperation and social organization by which the individual is understood as freely embedded in an institutionalized context of cooperation and self-identification. Sociality is explained as emerging from natural prerequisites of human beings and as counterpart of nature. The main target of this research is to investigate Hegel's theory of society by considering the relation he establishes with the natural prerequisites of individual human beings. In fact, individual cognitive capacities and shared practices are the outcome of the unfolding of an interpersonal substance called spirit determining the role of the individual in the social space. The notion of spirit is introduced by Hegel as both emerging and different from nature. As the nature of an animal is characterized by its autonomous interaction with the environment, so the nature of a rational being is characterized from a peculiar form of interaction, i.e. the reflexion on its own natural substratum. This speculative attitude is the premise for defining the ideal of freedom, whose achievement is the final end for human beings. This programme aims to investigate the mutual dependence between nature and spirit by updating Hegelian readings and by promoting the interdisciplinary dialogue with other fields of knowledge investigating the human cognitive dispositions. In order to achieve these objectives the ER will undertake an outgoing phase in the US under the supervision of a leading Hegelian. During the fellowship he will be also seconded to the Max Planck institute for Evolutionary Anthropology. This secondment aims to improve the exchange and the dialogue between different disciplines and to enhance the ER’s capacities to manage intersectional projects of research. The ER will also organize two international conferences, edit a collection of essays and publish a book.;244269;244269;H2020-MSCA-IF-2015;/MSCA-IF-GF;UNIVERSITA DEGLI STUDI DI PARMA;IT;;;;1;0;0;1;0;0 200045;693055;MedReset;SIGNED;H2020-EU.3.6.;INT-06-2015;H2020;MEDRESET.A comprehensive, integrated,and bottom-up approach to reset our understanding of the Mediterranean space, remap the region,and reconstruct inclusive, responsive,and flexible EU policies in it;2016-04-01;2019-08-31;;Euro-Mediterranean policies, as well as research on them, have been characterized by a Euro-centric approach based on a narrow geopolitical construction of the Mediterranean. Moreover, stakeholders, policy instruments, and policy issues have been defined from a European standpoint, marginalizing the perspectives and needs of local states and people, and ignoring the role played by new and powerful regional and global actors. In an increasingly multipolar world, overcoming this Euro-centric approach is key for Europe to play a more meaningful role in the region. Thus, MEDRESET aims to reset our understanding of the Mediterranean and develop alternative visions for a new partnership and corresponding EU policies, reinventing a future role for the EU as an inclusive, flexible, and responsive ‘actor’ in the region. This will be achieved through an integrated research design which is in three phases: it 1) de-constructs the EU construction of the Mediterranean, 2) counters it by mapping the region on the geopolitical level and in four key policy areas (political ideas, agriculture and water, industry and energy, migration and mobility) alongside a three-dimensional framework (stakeholders, policy instruments, policy issues), which directly feeds into 3) a reconstruction of a new role for the EU, enhancing its ability to exert reflexive leadership and thus its relevance in the region. Embedded in an interdisciplinary research team, as well as in a civil society and media network, MEDRESET evaluates the effectiveness and potential of EU policies by investigating whether current policies still match the changing geopolitical configuration of the Mediterranean area. The perceptions of EU policies and the reasons for their successes or failures are assessed by surveying top-down and bottom-up stakeholders on both shores of the Mediterranean. Country-tailored policy recommendations for the EU will be given for four key countries: Egypt, Lebanon, Morocco, and Tunisia.;2497056,25;2497056,25;H2020-INT-SOCIETY-2015;/RIA;ISTITUTO AFFARI INTERNAZIONALI;IT;"American University of Beirut;UNIVERSITY OF DURHAM;KOLEGIUM EUROPEJSKIE;ARAB STUDIES INSTITUTE - RESEARCH AND EDUCATION METHODOLOGIES;CAIRO UNIVERSITY;UNIVERSITE MOULAY ISMAIL;FACULTE DE DROIT ET DES SCIENCES POLITIQUES DE TUNIS;CENTRE FOR INTERNATIONAL INFORMATION AND DOCUMENTATION IN BARCELONA;KAMUSAL POLITIKA VE DEMOKRASI CALISMALARI DERNEGI;INSTITUT DE PREPARATION A L'ADMINISTRATION ET A LA GESTION;FORUM INTERNAZIONALE ED EUROPEO DI RICERCHE SULL'IMMIGRAZIONE ASSOCIAZIONE";"LB;UK;PL;EG;MA;TN;ES;TR;FR;IT";;1;0;0;1;0;0 200395;702178;VIAWORD;CLOSED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;From speech and print to meaning: an integrated account of word recognition in young and older adults.;2016-06-01;2018-09-20;;"Language is a uniquely human and complex cognitive process that is vital for our successful everyday interactions in the world. I propose to investigate neurophysiological mechanisms associated with orthographic, phonological and semantic processes of word recognition and how they are modulated by print (visual) and spoken (auditory) inputs (phase 1), and by healthy aging (phase 2). In phase 3, I will develop a biologically-plausible computational model of word recognition that will incorporate findings from phases 1 and 2. To achieve this, I will use an original multidisciplinary and interdisciplinary approach combining: psycholinguistics, cognitive neuroscience, cognitive psychology of aging, and computational modelling. My main predictions include that: (1) differences in neurocognitive mechanisms associated with orthography, phonology and semantics arise due to the temporally-extended (auditory) vs. all at once (visual) presentation of word; (2) decline in sensory acuity during aging affect subsequent neurocognitive mechanisms of word recognition causing greater reliance on later semantic processes than on earlier orthographic and phonological processes. Ultimately, my project can provide us with a much needed integrated account of normal neurocognitive processes during word recognition and can help us understand what declines and what is preserved in healthy aging. In turn, such understanding can help future research delineate bio-markers of early language deterioration and simulate remedial treatments.";170121,6;170121,6;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;BCBL BASQUE CENTER ON COGNITION BRAIN AND LANGUAGE;ES;;;;1;0;0;1;0;0 194228;644657;AutoMat;SIGNED;H2020-EU.2.1.1.4.;ICT-15-2014;H2020;Automotive Big Data Marketplace for Innovative Cross-sectorial Vehicle Data Services;2015-04-01;2018-03-31;;"Inside today's vehicles ~4000 CAN-Bus signals/sec are processed in comparison to very few signals in smart phones and alike. This large amount of continuously gathered vehicle data represents major big data business potentials, not only for the automotive industry but in particular for cross-sectorial industries with interdisciplinary applications. With today's proprietary approaches focusing on bringing services into vehicles and the applied ignorance of customer privacy concerns, this major business potential is still locked because the automotive industry was not yet able to establish an open service ecosystem equivalent to the ones in the smart phone industry. The core intention of the AutoMat project is to innovate an open ecosystem for Vehicle Big Data, materializing in the form of a cross-border Vehicle Big Data Marketplace that leverages currently unused information gathered from connected vehicles. The interface to the marketplace is derived from a Common Vehicle Information Model that makes mined and anonymous vehicle data from various OEMs accessible to cross-sectorial service providers. With the huge amount of volatile data from vehicles, the AutoMat ecosystem heavily builds upon current trends in Big Data. Exemplary service scenarios, driven by service providers dedicated to generate concrete businesses from the AutoMat ecosystem, are developed in the context of meteorological data based hyper local and extended innovative enterprise service domains. By defining an open value chain, the proposed AutoMat ecosystem enables and stimulates parties from different sectors to focus on their core businesses and to excel collaboration with other partners. AutoMat therefore may serve as incubator for new business opportunities strengthening Europe's position as provider of innovative cross-sectorial and cross-border Big Data services. The latter aspect is actively stimulated during the project by an Open Service Contest based upon the AutoMat Big Data ecosystem.";5751785,5;4460269;H2020-ICT-2014-1;/IA;VOLKSWAGEN AG;DE;"INSTITUT FÜR ANGEWANDTE SYSTEMTECHNIK BREMEN GMBH;METEOLOGIX AG;RENAULT SAS;CENTRO RICERCHE FIAT SCPA;ATOS SPAIN SA;ERPC EUROPEAN RESEARCH PROGRAMME CONSULTING GMBH;TECHNISCHE UNIVERSITAT DORTMUND;INSTITUT MINES-TELECOM;TRIALOG;METEOGROUP NEDERLAND BV;HERE GLOBAL B.V.";"DE;CH;FR;IT;ES;NL";;1;0;0;1;0;0 194298;645238;TRANSLITERACY;SIGNED;H2020-EU.2.1.1.;ICT-31-2014;H2020;Exploiting transmedia skills and informal learning strategies to improve formal education;2015-04-01;2018-03-31;;"The aims of the TRANSLITERACY project are to understand how teenagers are learning outside the school and to introduce those experiences into it. The ethnographic identification and analysis of the (trans)media skills will be at the centre of the research program. Once identified the informal learning strategies applied by young people outside the formal institutions, the team will translate them into a series of proposals to be implemented into the schools. The TRANSLITERACY Project will involve an interdisciplinary group of 25 senior and junior researchers with sound experience in fields such as media literacy, transmedia storytelling, user-generated contents and participatory culture, ludology, traditional and virtual ethnography, pedagogy and innovation in education. The research will focus on the following set of skills: • Problem-solving strategies developed by teens in video gaming (Videogame literacy) • Content creation, production and sharing strategies developed by teens in fan fiction (Participatory culture literacy). • Content creation, production and sharing strategies developed by teens in social media (Web / social networks literacy). The research will focus on 12-18 years old teens, an age characterized by a short but intensive experience in the use of new media and digital technologies. The fieldwork –based on surveys, interviews, focus groups, participant observation, and online activities analysis- will be simultaneously developed in 9 countries: Australia, Colombia, Finland, Italy, Mexico, Portugal, Spain, United Kingdom, and Uruguay. The duration of the research will be 3 years. After mapping the transmedia practices and informal learning strategies the team will produce an open and customizable Teacher’s Kit based on the outputs of the research. The kit will propose learning strategies and activities to be developed with students into the schools.";1066492,5;1066489;H2020-ICT-2014-1;/RIA;UNIVERSIDAD POMPEU FABRA;ES;"UNIVERSIDADE DO MINHO;PONTIFICIA UNIVERSIDAD JAVERIANA;FUNDACIO PER A LA UNIVERSITAT OBERTA DE CATALUNYA;JYVASKYLAN YLIOPISTO;UNIVERSITA DEGLI STUDI DI TORINO;UNIVERSIDAD DE LA REPUBLICA;ARS MEDIA SRL;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD";"PT;CO;ES;FI;IT;UY;UK";;1;0;0;1;0;0 215627;798275;TRANSPHILEUR;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;TOWARD A PHILOSOPHICAL RETHINKING OF TRANSLATION: Effects of Translation in aContemporary European Space;2018-08-01;2020-07-31;;This research project deals with the phenomenon of translation in order to investigate its philosophical structure, logic and character and thus to contribute to the affirmation and development of the philosophy of translation as a relevant research discipline. The research proposes a conception of translation as a self-reflexive transformational practice, investigating at the same time importance and effectiveness of translation in the contemporary European political and cultural context. The interdisciplinary character of the project requires a combination of philosophy, translation studies, cultural theory and political theory. The research aims to have a broad impact and takes into account the practical effectiveness of its main ideas for addressing some of the current social and political issues in Europe. The proposal includes training-through-research at the participating organisations, acquirement of new experiences and skills, a two-way-transfer of knowledge, teaching, organization of a workshop, participation in conferences, and planning for publications. Results will be disseminated to the academic community of experts and to the wider audience as well. The project is in line with the key priorities of the Horizon 2020 Work Programmes 2016-17 and 2018-20, i.e., with the integration of social sciences and humanities in promoting the European Public and Cultural Space.;168277,2;168277,2;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;UNIVERSITA DEGLI STUDI DI PADOVA;IT;;;;1;0;0;1;0;0 194099;643739;HEIM;CLOSED;H2020-EU.1.3.3.;MSCA-RISE-2014;H2020;Higher Education Internationalisation and Mobility: Inclusion, Equalities and Innovations;2015-01-01;2017-12-31;;"The proposed research/innovation project (HEIM) focuses on how principles of equity and inclusion can be applied to internationalisation strategies and programmes in higher education, at both staff and student levels. It focuses on the Roma community in Europe as a critical example of a marginalised group. HEIM will interrogate and develop the concept and practices of higher education internationalisation in Europe through questions about who is able to participate in and benefit from policy initiatives and strategic interventions. It asks whether certain social groups are disadvantaged or excluded from the opportunities that mobility offers. It will examine motivations and experiences, and the hidden costs of border crossings in terms of socio-political and affective considerations. Its objectives include comparative investigation of data on who is participating in selected internationalisation programmes; producing accounts based on literature, statistical data and empirical research. It will create a set of guidelines for reflexive and inclusive approaches to the internationalisation of higher education. Through its interdisciplinary and intersectoral approaches, it will contribute to methodological innovation across different fields. It will build research and innovation capacity by constructing teams and sharing knowledge between early stage and experienced researchers. It will exchange knowledge about internationalisation programmes in the partner organisations via co-written papers, statistical datasets, literature reviews, training and workshops. The Partnership is between three universities (Sussex, Ume? and Seville) and a non-academic organisation, the Roma Education Fund (REF). Via secondments, staff exchange, training and collaborative inquiry, the project will investigate internationalisation policies, interventions and methodologies in different national locations.";207000;207000;H2020-MSCA-RISE-2014;/MSCA-RISE;THE UNIVERSITY OF SUSSEX;UK;"ROMA OKTATASI ALAP;UMEA UNIVERSITET;UNIVERSIDAD DE SEVILLA";"HU;SE;ES";;1;0;0;1;0;0 194060;643398;EURO-HEALTHY;CLOSED;H2020-EU.3.1.6.;PHC-31-2014;H2020;Shaping EUROpean policies to promote HEALTH equitY;2015-01-01;2017-12-31;;"Health inequities have been increasing in Europe, particularly in a context of an ageing society and economic crisis. In countries with different levels of infrastructures and health system preparedness, inequities create significant policy challenges. The main goal of this project is to advance knowledge of policies that have the highest potential to enhance health and health equity across European regions with particular focus on metropolitan areas. To achieve this goal, the project will develop tools – based on a population health index – to evaluate the health and wellbeing of European population. This index will be informed by evidence on the relationship between multiple determinants (e.g. demographic, social, economic, environmental, lifestyle, and health care) and health outcomes in the past 15 years. It will be constructed using a multicriteria model structure, following a socio-technical approach: integrating the technical elements of a multicriteria value model and the social elements of interdisciplinary and participatory processes. The index will be applied to evaluate the population’s health in 273 NUTS 2 European regions and 9 selected pilot metropolitan areas (covering populations of 28 EU countries). The space-time analysis and comparison of the population health index will be enabled by a user-friendly web-based Geographic Information System. The population health index will be used to foresee and discuss the impact of multilevel policies and combinations of policies in population health and health equity across European regions, thus providing a basis for policy dialogue. Multicriteria resource allocation models, conflict analyses, analysis of policies’ feasibility, and scenario analyses will then assist in providing evidence on which policies have the highest potential to improve health and reduce health inequities at different geographical levels, and in suggesting alternative policy options for health policy development and regulation.";2999480;2999479,75;H2020-PHC-2014-single-stage;/RIA;UNIVERSIDADE DE COIMBRA;PT;"ETHNIKO KAI KAPODISTRIAKO PANEPISTIMIO ATHINON;VRIJE UNIVERSITEIT BRUSSEL;UNIVERSITEIT MAASTRICHT;UNIVERSITE PARIS NANTERRE;Department of Health;EKONOMICKA UNIVERZITA V BRATISLAVE;AZIENDA SANITARIA LOCALE TO3;KAROLINSKA INSTITUTET;UNIVERZITA KARLOVA;Agencia de Salut Publica de Barcelona;UNIVERSITY COLLEGE LONDON;BEUTH-HOCHSCHULE FUER TECHNIK BERLIN;INSTITUTO SUPERIOR TECNICO;CONSORZIO PER IL SISTEMA INFORMATIVO (CSI PIEMONTE)";"EL;BE;NL;FR;UK;SK;IT;SE;CZ;ES;DE;PT";;1;0;0;1;0;0 194079;643576;FRESHER;CLOSED;H2020-EU.3.1.6.;PHC-31-2014;H2020;FoResight and Modelling for European HEalth Policy and Regulation;2015-01-01;2017-12-31;;"FRESHER brings together ten research groups, including leaders in the management of large European Foresight projects and highly experienced health policy modelers, in an interdisciplinary team engaged in FoResight and Modelling for European Health policy and Regulation. The overall project objective is the representation of alternative futures where the detection of emerging health scenarios will be used to test future policies to effectively tackle the burden of non communicable diseases (NCDs). The project will produce quantitative estimates of the future global burden of NCDs in the EU and its impact on health care expenditures and delivery, population well-being, health and socio-economic inequalities, and potential changes in these impacts according to alternative health and non-health policy options. The added value of FRESHER lies in the fact that these estimates: - will not only be based on extrapolation of past health trends but also on foresight techniques (mapping of risk factors, horizon scanning and identification of key drivers for change, scenarios building) giving credit to the interdependencies of structural long-term trends in demography, gender relations, technological, economic, environmental, and societal factors at 2050. - will be produced through the development of an empirically-based micro-simulation model (starting from the Chronic Disease Policy Model of OECD), allowing to quantify the current and future health and economic impacts of NCDs and testing “what if” policy options according to alternative foresight scenarios, as well as potential new policies and policy combinations. FRESHER heavily relies on an interactive process with key stakeholders, at all stages of the project, in elaborating the framework, and giving inputs for the qualitative foresight scenarios and the quantitative micro-simulation model, and in deriving recommendations for future policies affecting population health and well-being.";2650407,5;2650407,5;H2020-PHC-2014-single-stage;/RIA;UNIVERSITE D'AIX MARSEILLE;FR;"ISTITUTO DI STUDI PER L'INTEGRAZIONE DEI SISTEMI (I.S.I.S) - SOCIETA'COOPERATIVA;AIT AUSTRIAN INSTITUTE OF TECHNOLOGY GMBH;INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE;IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE;SLASKIE CENTRUM CHOROB SERCA W ZABRZU;ISTITUTO SUPERIORE DI SANITA;Fourth View Consulting;TERVEYDEN JA HYVINVOINNIN LAITOS;EUROPEAN PUBLIC HEALTH ALLIANCE;UNIVERSIDAD DE VIGO";"IT;AT;FR;UK;PL;EE;FI;BE;ES";;1;0;0;1;0;0 197118;664557;LignoSilva;SIGNED;H2020-EU.4.a.;WIDESPREAD-1-2014;H2020;Centre of Excellence of Forest-based Industry;2015-06-01;2016-05-31;;"The general objectives of the project is to create the Centre of excellence (LignoSilva) in the field of a forestry, wood-processing and a pulp-paper complex involving two major organizations, the National Forest Centre in Zvolen and Pulp and Paper Research Institute in Bratislava in cooperation with the European Forest Institute as a leading research organisations from high performance countries of the EU. LignoSilva will help to strategically transform Forest-based sector of the region towards the innovation growth based on the knowledge economy (in terms of RIS 3 SK vision) and the implementation of the principles of Green Economy. LignoSilva will represent the Centre of excellence that integrates research, development and innovation potential of a Forest-based industry that rationally links the chain of wood production, processing and utilisation. Project covers 4 interlinked priority areas: 1. Forest resources and sustainable wood production 2. Biomass and bioenergy 3. Paper-pulp technologies 4. Recycling and cascading system of wood and wood products use The intention of the project partners is to establish an autonomous entity by grouping a number of existing facilities into one cluster. CSA and FPA will be directed so that the newly established CE can benefit from massive past investments whilst bringing more dynamics into the forest based industry in Slovakia The CE will benefit from European Forest Institute and its network participation. EFI with its member is in a unique position to provide collective science-based insights at European and regional level to support informed policy making. Concerning LignoSilva EFI's Research function aims to (i) Conduct and promote interdisciplinary and cross-sector research of Forest-based industry and (ii) Support the coordination, strengthening and networking of forest research capacities aiming to overcome the fragmentation and low performance of FBI in Slovakia.";467438;467438;H2020-WIDESPREAD-2014-1;/SGA-CSA;NARODNE LESNICKE CENTRUM;SK;"EUROPEAN FOREST INSTITUTE;VYSKUMNY USTAV PAPIERA A CELULOZY AS";"FI;SK";;1;0;0;1;0;0 197135;666438;DoReMIR;CLOSED;"H2020-EU.2.1.1.;H2020-EU.2.3.1.";ICT-37-2014;H2020;Automatic music transcription of polyphonic audio;2015-04-01;2017-09-30;;"DoReMIR Music Research has already launched several successful products for music analysis and composition and has a large user base of monophonic audio analysis worldwide. The project builds on and extends a product suite called ScoreCloud with the focus on easy creation and distribution of music notation. The ScoreCloud concept is technically built on mobile and desktop apps connected with a full cloud based back-end. The product enables users to notate music directly from performance: a Google Translate for Music! The project will develop a low-cost, cloud-based, polyphonic audio transcription solution based on an interdisciplinary approach (musicology, acoustics, audio engineering, cognitive science and computing) and a user-driven design (agile iterative solution development with end-user participation in the context of music teaching and music composition). In order to circumvent the limitations of current automated transcription methods, the project uses a novel approach to musical and music signal analysis, by modelling and using high-level musical knowledge (about stylistic conventions, music cognition, etc.) and machine learning techniques. In addition to finding better solutions to certain analysis problems, the resulting systems will also be able to communicate their results in musically meaningful, high-level terms.";2980375;2086262,5;H2020-SMEINST-2-2014;/SME-2;DOREMIR MUSIC RESEARCH AB;SE;;;;1;0;0;1;0;0 205188;682574;ASSIMILES;SIGNED;H2020-EU.1.1.;ERC-CoG-2015;H2020;Advanced Spectroscopy and Spectrometry for Imaging Metabolism using Isotopically-Labeled Endogenous Substrates;2016-09-01;2021-08-31;;"A technological revolution is currently taking place making it possible to noninvasively study metabolism in mammals (incl. humans) in vivo with unprecedented temporal and spatial resolution. Central to these developments is the phenomenon of hyperpolarization, which transiently enhances the magnetic resonance (MR) signals so much that real-time metabolic imaging and spectroscopy becomes possible. The first clinical translation of hyperpolarization MR technology has recently been demonstrated with prostate cancer patients. I have played an active role in these exciting developments, through design and construction of hyperpolarization MR setups that are defining the cutting-edge for in vivo preclinical metabolic studies. However, important obstacles still exist for the technology to fulfill its enormous potential. With this highly interdisciplinary proposal, I will overcome the principal drawbacks of current hyperpolarization technology, namely: 1) A limited time window for hyperpolarized MR detection; 2) The conventional use of potentially toxic polarizing agents; 3) The necessity to use supra-physiological doses of metabolic substrates to reach detectable MR signal I will develop a novel hyperpolarization instrument making use of photoexcited compounds as polarizing agents to produce hyperpolarized solutions containing exclusively endogenous compounds. It will become possible to deliver hyperpolarized solutions in a quasi-continuous manner, permitting infusion of physiological doses and greatly increasing sensitivity. I will also use a complementary isotope imaging technique, the so-called CryoNanoSIMS (developed at my institution over the last year), which can image isotopic distributions in frozen tissue sections and reveal the localization of injected substrates and their metabolites with subcellular spatial resolution. Case studies will include liver and brain cancer mouse models. This work is pioneering and will create a new frontier in molecular imaging.";2199145,76;2199145,76;ERC-2015-CoG;/ERC-COG;THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;UK;;;;1;0;0;1;0;0 204485;694476;EMoBookTrade;SIGNED;H2020-EU.1.1.;ERC-ADG-2015;H2020;The Early Modern Book Trade: An Evidence-based Reconstruction of the Economic and Juridical Framework of the European Book Market;2016-09-01;2021-08-31;;"This project will explore the idea – and gather the evidence to prove it – that the so-called printing revolution does not consist in a change in book-making technology but in the process, prolonged over the entire course of the early modern age, of the formation of the printed book market and the creation of readers as purchasers and consumers of books. In order to demonstrate this, the project will reconstruct the economic and legal framework of the European book market by applying an interdisciplinary approach to the economic study of book history. By using unique and hitherto unexplored documentary evidence, this project addresses four fundamental questions relating to the growth of a fully developed book trade and the rise of a society of book consumers within the social and religious context of early modern Europe: the economic issue of book prices; the juridical and political issue of the book privilege system (which in turn influenced the process of book pricing); the management of the bookselling business (focusing on businesses in two major cities in the European book trade, Venice (Bernardino Giunti) and Antwerp (Christopher Plantin)); the technique of building and managing a transnational network for book distribution and sale (analyzing groundbreaking new evidence, an entire year (1522) of correspondence from a Venetian wholesale bookseller, Giovanni Bartolomeo Gabiano). These four research areas will feed into an overarching project which will examine the impact of books and the access of readers to them, together with the development in patterns of cultural consumption which meant that printed books lost the luxury status which they had had throughout the incunabula period to become transformed into ‘popoluxe’ goods.";1434375;1434375;ERC-2015-AdG;/ERC-ADG;UNIVERSITA DEGLI STUDI DI MILANO;IT;UNIVERSITA DEGLI STUDI DI UDINE;IT;;1;0;0;1;0;0 204476;692502;L2STAT;SIGNED;H2020-EU.1.1.;ERC-ADG-2015;H2020;Statistical learning and L2 literacy acquisition: Towards a neurobiological theory of assimilating novel writing systems;2016-07-01;2021-06-30;;The overarching goal of L2STAT is to understand L2 literacy acquisition by bringing together, for the first time, recent advances in the neurobiology of statistical learning (SL), a detailed statistical characterization of the world’s writing systems, and neurally-plausible general principles of learning, representation, and processing. L2STAT aims to provide a new theoretical framework that considers L2 learning and SL a two-way street: SL, on the one hand, tunes learners to the regularities of a new linguistic environment, and on the other hand, L2 environment shapes learners’ sensitivity to its specific types of statistical properties. The project will focus on the assimilation of reading skills in four novel linguistic environments, and investigate how exposure to their distinct writing systems shape, in turn, SL. L2STAT is an interdisciplinary project that launches in parallel five mutually informative research axes: 1) we employ advanced methods from computational linguistics and machine learning to precisely characterize the statistics of four highly contrasting writing systems (English, Spanish, Hebrew, Chinese). 2) We study the learning that results from biologically-inspired computational models that are exposed to these statistics, to generate a priori predictions regarding what statistical properties can (or cannot) be learned, and how neural mechanisms constrain the representations learned during L2 literacy acquisition. 3) We develop psychometrically reliable behavioral tests of individuals’ capacities to extract regularities in the visual and auditory modalities. 4) We use state of the art neuroimaging techniques including EEG, MEG, fMRI to probe the neurobiological underpinning for detecting regularities in the visual and auditory modalities. 5) We conduct behavioral experimentation in four sites (Israel, Spain, Taiwan to track literacy acquisition longitudinally in the four different languages.;2500000;2500000;ERC-2015-AdG;/ERC-ADG;THE HEBREW UNIVERSITY OF JERUSALEM;IL;BCBL BASQUE CENTER ON COGNITION BRAIN AND LANGUAGE;ES;;1;0;0;1;0;0 200932;701269;GoldOpera;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Carlo Goldoni and Europe's New Opera Theatre;2016-03-01;2018-02-28;;"Venetian playwright Carlo Goldoni (1707-1793), famous for his ‘reform’ of comic theatre, was also a prolific librettist. Research has focused largely on Goldoni’s early texts for music, while the libretti written during his mature years have remained overshadowed by his most famous comedies. With growing attention to interdisciplinary studies, the time is now ripe for these later texts for music and the operas drawn from them to be brought to light, because, most importantly, precisely through these libretti Goldoni became a pioneer in the creation of the 'dramma giocoso,' a new genre of opera that would span a long legacy throughout Europe, all the way to the works of W.A. Mozart and Lorenzo Da Ponte. The goal of this project is the recovery and analysis of operatic renditions created from the innovative drammi giocosi by Goldoni, today nearly forgotten, to finally supply a comprehensive picture of the interaction between text, music, and theatre that fueled the radical evolution of Classical opera in the later 18th century. The study of these selected works will also yield a more detailed map of the artistic collaborations and diffusion of this new genre on an international scale. On a broader horizon, this project ultimately aims to create the basis for the restoration, publication, and performance of historical opera scores that have vanished from the traditional repertoire. These operas will become a source of new discoveries in both literary and musical fields, and their restoration through performance with the involvement of young musicians and scholars in conservatories and universities will not only render just merit to Goldoni for his innovations in opera theatre, but most importantly will bring to a larger public new knowledge of a form of art that had a global impact, and therefore a deeper understanding of our shared cultural heritage.";180277,2;180277,2;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;UNIVERSITA CA' FOSCARI VENEZIA;IT;;;;1;0;0;1;0;0 193751;640800;AQuS;CLOSED;H2020-EU.1.2.2.;FETPROACT-3-2014;H2020;Analog quantum simulators for many-body dynamics;2015-01-01;2017-12-31;;Quantum simulators promise to provide unprecedented insights into physical phenomena not accessible with classical computers and have the potential to enable radically new technologies. In this proposal, we argue that analog dynamical quantum simulators are currently realisable and constitute a most promising class of architectures to fulfil the ultimate promise to devise quantum machines outperforming classical computers. The approach taken is two-pronged: On the one hand, we devise versatile and practical platforms for dynamical simulators – making use of systems of ultra-cold atoms in optical lattices and the continuum, as well as cavity polaritons. We suggest a concerted and interdisciplinary research programme of certifying quantum devices and assess them in their computational capabilities, addressing largely unexplored key questions on the power of quantum simulators. On the other, we make use of those devices to probe important questions in fundamental and applied physics, ranging from technology-relevant problems, concerning transport processes or glassy dynamics, via long-standing challenges in the physics of non-equilibrium and thermalisation phenomena, through puzzles in notions of quantum turbulence, to questions in the study of quantum gravity.;2000500;2000500;H2020-FETPROACT-2014;/RIA;RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG;DE;"TECHNISCHE UNIVERSITAET WIEN;LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN;CONSIGLIO NAZIONALE DELLE RICERCHE;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FREIE UNIVERSITAET BERLIN";"AT;DE;IT;FR";;1;0;0;1;0;0 193405;636501;EDEN ISS;SIGNED;H2020-EU.2.1.6.1.;COMPET-07-2014;H2020;Ground Demonstration of Plant Cultivation Technologies and Operation in Space for Safe Food Production on-board ISS and Future Human Space Exploration Vehicles and Planetary Outposts;2015-03-01;2019-04-30;;Humanity’s plans to further explore space require the development of bio-regenerative life support systems and in particular plant cultivation. Plants contribute to all major life support functions by producing food and oxygen, reducing carbon dioxide and recycling water and waste. Moreover, fresh crops also have a positive impact on crew psychological well-being. EDEN ISS aims to adapt, integrate and demonstrate plant cultivation technologies and operations procedures for safe food production on-board the International Space Station and for future human space exploration missions. The consortium will demonstrate operational capability of controlled environment agriculture technologies and procedures for safe food production in space. A mobile test facility will be built to provide realistic interfaces analogous to ISS. A one-year demonstration campaign at the Neumayer III Antarctic station will provide extensive testing and validation capability to increase the technology readiness level of key subsystems to 6. Further developing these technologies and operations procedures, including food quality and safety measurements, will also contribute to Europe’s interest in resource efficient crop cultivation, saving energy, countering the climate change and securing the supply of healthy and safe food. The interdisciplinary nature of EDEN ISS combines research in space engineering, horticulture, food science and microbiology. Leading space industries (Thales Alenia Space Italia, Airbus Defense and Space, Telespazio), research organizations (DLR, CNR, AWI), SMEs (Liquifer, Heliospectra, EnginSoft, Aero Sekur) and academia (Wageningen UR, University of Guelph, Limerick Institute of Technology) from six European countries (Germany, Ireland, Italy, Sweden, Austria, the Netherlands) and Canada join forces in a unique consortium to prepare the ground for further innovative research and development in human spaceflight and terrestrial applications.;4550867,5;4535869;H2020-COMPET-2014;/RIA;DEUTSCHES ZENTRUM FUER LUFT - UND RAUMFAHRT EV;DE;"UNIVERSITY OF GUELPH NON-PROFIT CORPORATION;TELESPAZIO SPA;LIQUIFER SYSTEMS GROUP GMBH;THALES ALENIA SPACE ITALIA SPA;AIRBUS DEFENCE AND SPACE GMBH;ARESCOSMO S.P.A.;ALFRED-WEGENER-INSTITUT HELMHOLTZ-ZENTRUM FUR POLAR- UND MEERESFORSCHUNG;CONSIGLIO NAZIONALE DELLE RICERCHE;HELIOSPECTRA AB;ENGINSOFT SPA;AIRBUS DS GMBH;LIMERICK INSTITUTE OF TECHNOLOGY;STICHTING WAGENINGEN RESEARCH";"CA;IT;AT;DE;SE;IE;NL";;1;0;0;1;0;0 194169;644202;GEAGAM;CLOSED;H2020-EU.1.3.3.;MSCA-RISE-2014;H2020;Geophysical Exploration using Advanced GAlerkin Methods;2015-01-01;2017-12-31;;"The main objective of this Marie Curie RISE action is to improve and exchange interdisciplinary knowledge on applied mathematics, high performance computing, and geophysics to be able to better simulate and understand the materials composing the Earth's subsurface. This is essential for a variety of applications such as CO2 storage, hydrocarbon extraction, mining, and geothermal energy production, among others. All these problems have in common the need to obtain an accurate characterization of the Earth's subsurface, and to achieve this goal, several complementary areas will be studied, including the mathematical foundations of various high-order Galerkin multiphysics simulation methods, the efficient computer implementation of these methods in large parallel machines and GPUs, and some crucial geophysical aspects such as the design of measurement acquisition systems in different scenarios. Results will be widely disseminated through publications, workshops, post-graduate courses to train new researchers, a dedicated webpage, and visits to companies working in the area. In that way, we will perform an important role in technology transfer between the most advanced numerical methods and mathematics of the moment and the area of applied geophysics.";580500;580500;H2020-MSCA-RISE-2014;/MSCA-RISE;UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA;ES;"INSTITUT NATIONAL DE RECHERCHE ENINFORMATIQUE ET AUTOMATIQUE;TOTAL S.A.;BCAM - BASQUE CENTER FOR APPLIED MATHEMATICS;BARCELONA SUPERCOMPUTING CENTER - CENTRO NACIONAL DE SUPERCOMPUTACION";"FR;ES";;1;0;0;1;0;0 193946;642771;SPARCARB;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2014-EID;H2020;Lightning protection of wind turbine blades with carbon fibre composite materials;2015-01-01;2018-12-31;;"The consortium behind SPARCARB – Global Lightning Protection Services A/S (GLPS, non-academic beneficiary), Denmark, together with the University of Southampon (SOTON, academic beneficiary entitled to award doctoral degrees), UK, and six Partner organizations – aims at providing an innovative international, interdisciplinary and intersectoral training network for four Early-Stage Researcher (ESRs), which will integrate in a single project (1) Science-based Training in material and electrical engineering; (2) Transferable Skills-based Training in carbon fibre, wind turbines, lightning protection technologies, business and innovation, and other competences; (3) and Research-based Training designed around cutting-edge challenges for the Wind Power Industry, which has identified the need for continuous research on lightning protection of large wind turbines with blades incorporating CFC structural components. The SPARCARB project aims at addressing the strong lack of doctoral-level trained human resources to push forward the research base in the field of lightning protection of CFC structures, building the proper environment for shifting paradigms in the Wind Power Industry. Specifically, the project will address scientific and technological challenges related to an effective protection of CFC wind turbine blades from lightning-induced damages, enabling the reliable use of very large and more efficient wind turbines. The goal is to train four ESRs to be familiar with both Industry (15 months at GLPS and secondments to industrial partner organizations for 3 months) and Academia (18 months at SOTON The doctoral training programme will be carried out according to SOTON’s criteria from which all four ESRs will obtain doctoral degrees. The envisaged training will provide a range of skills to all ESRs making them high-potential candidates to be employed at GLPS and other wind power industry players.";1093151,52;1093151,52;H2020-MSCA-ITN-2014;/MSCA-ITN-EID;UNIVERSITY OF SOUTHAMPTON;UK;GLOBAL LIGHTNING PROTECTION SERVICES AS;DK;;1;0;0;1;0;0 193825;641515;GALENA;SIGNED;H2020-EU.2.1.6.;GALILEO-2-2014;H2020;Galileo-based solutions for urban freight transport;2015-01-01;2017-03-31;;Urban Freight Transport action relates to find solutions to better manage and monitor freight transport flows and ensure efficient last-mile delivery, while maximizing the economic efficiency of urban distribution, and minimizing the environmental and social impacts. GALENA develops the hardware equipment as well as the information system and the supervision platform needed for the cross supply chain orchestration of a community of shippers involved in urban freight pooling particularly for the last-mile delivery. GALENA relies on the development of a robust and GNSS-based liability binding application, enabling the different carrier operators to join a Mutualized Transportation Community to timestamp, geo-locate and formalize (as a real authentication) their trip as well as any events occurring during the shipping. An innovative, accurate and affordable hybrid system (Galileo/RTLS) will be developed for this purpose ensuring a seamless, robust and continuous handover indoor/outdoor localization and continuous, real-time, reliable, accurate and available Position, Velocity and Time (PVT) of carriers and high value parcels. An already existing logistics information systems will be adapted to exchange and store shipment authenticated data between all stakeholders, ensuring the traceability of goods, management of status changes while drawing up an objective review of the sharing of added value between the various stakeholders of a shared supply chain. A web service application will be set up for continuously supervising transactions and support to the orchestration decision making process. A truly interdisciplinary collaboration between GNSS, wireless sensors, logistics information systems, urban logistics and freight transport experts is set up to meet the objectives. The consortium gathers 8 EU partners committed within 2-year project to disseminate results towards potential customers and confirm the conditions for a successful larger scale deployment.;1267238,75;954932,75;H2020-Galileo-2014-1;/IA;TRI-VIZOR NV;BE;"CYBERENS TECHNOLOGIES AND SERVICES;IIDRE;ETHNIKO KAI KAPODISTRIAKO PANEPISTIMIO ATHINON;INSTYTUT GEODEZJI I KARTOGRAFII;HELILEO SA;NEBUSENS, S.L.;MARSEILLE GYPTIS INTERNATIONAL";"FR;EL;PL;ES";;1;0;0;1;0;0 209738;726217;MFreeB;SIGNED;H2020-EU.1.1.;ERC-2016-COG;H2020;Membrane-Free Redox Flow Batteries;2017-06-01;2022-05-31;;"The environmental concerns over the use of fossil fuels have promoted great interest in generating electric energy from renewable sources such as solar and wind. However, the intermittent nature of those resources demands high performing and cost-effective energy storage systems. Redox Flow Batteries (RFBs) present several advantages, namely, total decoupling of power and energy densities and the possibility of rapid mechanical charging by substituting spent electrolytes with fresh ones. The major issues of the current Vanadium RFBs are the high price and toxicity of vanadium components and the high cost and low performance of the ion-selective membranes they require. MFreeB project proposes to completely remove the problematic membrane of RFBs by developing a disruptive, versatile and scalable concept of Membrane-Free RFB implementing efficient catholytes and anolytes in which the metallic redox pairs are replaced by cheap, abundant and environmental-friendly molecules. In order to achieve this objective, I propose a multi- and interdisciplinary research methodology across a wide range of expertise including fundamental electrochemistry, thermodynamics, physical chemistry, modelling, and mechanical engineering. I will make use of advantages of different electrolytes to develop a versatile concept of Membrane-Free RFB with a wide range of applications. This Consolidator Grant (ERC) would provide adequate support to consolidate my own independent research team and programme. During my scientific career, I have demonstrated creative thinking and excellent capacity to carry out research going beyond the state of the art. My meritorious record of scientific publications (55 ISI articles, h index = 25), project leadership, international collaborations and capacity for supervising and coordinating a research team are presented in the proposal. I am now in an excellent position and research environment to commit and be devoted to this encouraging and challenging project";1998407,01;1998407;ERC-2016-COG;/ERC-COG;Fundacion IMDEA Energia;ES;;;;1;0;0;1;0;0 193881;642068;CLOSPORE;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2014-ETN;H2020;UNDERSTANDING THE CLOSTRIDIUM SPORE, A PREREQUISTE FOR DISEASE INTERVENTIONS AND EXPLOITATION;2015-01-01;2018-12-31;;Bacterial endospores are the most resistant life-forms on earth and the most important single feature of the genus Clostridium. Thus, whilst the pathogenesis of its notorious pathogens (C. botulinum, C. perfringens and C. difficile) is ascribed to the devastating toxins produced (neurotoxins, endotoxins and cytotoxins), it is their capacity to produce spores that lies at the heart of the diseases they cause. This is because spores play the pivotal role in the spread of infection (eg, C. difficile) and in foodstuff contamination and food poisoning (eg, C. botulinum and C. perfringens). The processes of spore formation (sporulation) and germination (return of the dormant spore to toxin-producing, vegetative cells), therefore, represent key intervention points. On the other hand, the majority of clostridia are entirely benign and can sustainably produce all manner of useful chemicals and fuels. Crucially, the regulation of chemical production is intimately linked to that of sporulation. Spores of benign species may also be used as a delivery system for treating cancer. Yet, despite the spore’s importance, little is known of the developmental processes of sporulation and germination. This is because research and training efforts on Clostridium spores are fragmented and there is no coherence between researchers working on pathogenic and industrially important species. CLOSPORE will address this deficiency by pooling the resources of Europe’s leading universities, research organisations and companies, to create an intersectorial Research and Training Programme that is multi-facetted, interdisciplinary and focused on clostridial spores. Accordingly, CLOSPORE will produce the innovative, applied research leaders of the future, able to tackle the big societal challenges facing Europe and the world.;3910777,56;3910777,56;H2020-MSCA-ITN-2014;/MSCA-ITN-ETN;THE UNIVERSITY OF NOTTINGHAM;UK;"NIZO FOOD RESEARCH BV;HELSINGIN YLIOPISTO;Green Biologics Ltd.;UNIVERSIDADE NOVA DE LISBOA;INSTITUT PASTEUR;PURAC BIOCHEM BV;INSTITUTO DE TECNOLOGIA QUIMICA E BIOLOGICA - UNIVERSIDADE NOVA DE LISBOA;STICHTING WAGENINGEN RESEARCH";"NL;FI;UK;PT;FR";;1;0;0;1;0;0 220557;829044;SCHINES;SIGNED;H2020-EU.1.2.1.;FETOPEN-01-2018-2019-2020;H2020;Spatially-Separated Chirality Inspired Networks;2019-01-01;2022-12-31;;Creating a brain-inspired technology through neuromorphic engineering could achieve or even surpass the extraordinary ability of the brain to grasp the world, which operates at an extremely low power consumption yet with the most complex interconnectivity known to mankind. The main goal of SCHINES is to set a clear direction to solve one of the biggest technological challenges that hinders this revolution: in existing physical neural network architectures, the desired interconnectivity can hardly be achieved. We will fabricate and design devices to demonstrate radically improved signal routing using topological metals. The design principle is simple: the environment of chiral electrons, electrons with spin locked to its momentum, can be engineered to create rich electronic lensing effect, analogous yet broader to light in-media propagation. Positive and negative effective indices of refraction for electrons, and lossless signal crossing can be engineered while maintaining, selecting or filtering the intrinsic topological protection of chirality, a degree of freedom that can be used for computation. These design principles are the basis for our device goal with scalable interconnectivity and are highly transferrable: they apply to strained materials, magnetic domains and heterostructures. This ambitious goal is realistic due to the interdisciplinary breadth of the SCHINES consortium: it is built out of established and emerging leaders called to shape the future of the field, joined in a public-private collaboration. They comprise an expertise that bridges the gap between the most abstract quantum field theory calculations with microscopic modelling with sample fabrication and measurement finalizing in device assembly;2313830;2313829,25;H2020-FETOPEN-2018-2019-2020-01;/RIA;IBM RESEARCH GMBH;CH;"MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS";"DE;FR";;1;0;0;1;0;0 209580;748354;NonnegativeRank;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Geometry of Nonnegative Rank;2017-09-01;2019-08-31;;This proposal is centered on nonnegative rank - a notion that modifies the definition of matrix rank. This project is basic research aimed to better understand the geometry of matrices and tensors of nonnegative rank at most r, how this knowledge can be employed to improve exact and numerical nonnegative matrix algorithms, obtain an algorithm for nested polytopes in dimension three, and address questions about mixture models in statistics. Computing and understanding nonnegative rank is truly interdisciplinary. Completing this project requires techniques from polyhedral geometry, real algebraic geometry, optimization, statistics, symbolic algebra, and numerics.;166603,2;166603,2;H2020-MSCA-IF-2016;/MSCA-IF-GF;UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6;FR;;;;1;0;0;1;0;0 209273;748170;ProFrost;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Theoretical and Numerical Analysis of Antifreeze and Ice Nucleator Proteins:Coarse-Grain Approach for Multiscale Study and Bio-Engineering;2018-09-01;2020-08-31;;"In nature there are many organisms able to control the ice nucleation rate of water. This ability allows such organisms to adapt to environmental changes, like large temperatures excursions, and to facilitate the search for food. Bio-molecules such as antifreeze proteins (AFPs) and ice nucleator proteins (INPs) are known to influence the ice nucleation rate, a feature that attracts great interest from a wide spectrum of scientific disciplines like biology and atmospheric science, and it offers several technological applications like cryo-preservation of tissues and increasing frozen food shelf life. I propose a new approach, based on a novel combination of water-protein coarse-grain model, able, for a wide range of temperatures and pressures, to deeply explore the configurational space of a water-protein solutions. The ProFrost project aims at defining a novel theoretical framework within which it will be possible to study how the folding properties of AFPs and INPs affect the thermodynamic state point of water. The main goal of the project is to understand the influence of protein interfaces on the dynamical and structural properties of water. The success of this project will pave the way for the computer based design of artificial functionalized protein sequences capable of influencing the phase of water. This project follows an innovative research line, with a multi-scale approach that combines multiple fields of research, such as physics, biology and chemistry. This research due to its interdisciplinary character and broad interest, has large impact and is often subject of publications on relevant international scientific journals, such as Nature, Science, Proceeding of National Academy of Science, Physical Review Letters. ProFrost will be carried out under the supervision of Prof Carlos Vega, a leading expert on water, and in collaboration with Prof. Dellago and Dr. Coluzza, expert in modelling and simulations of biophysical systems,";158121,6;158121,6;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;UNIVERSIDAD COMPLUTENSE DE MADRID;ES;;;;1;0;0;1;0;0 208982;749537;DRYSTORE;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Exploring dry storage as an alternative biobanking strategy inspired by Nature;2017-09-01;2019-08-31;;Biobanking under liquid nitrogen (LN) has satisfactory efficiency but it comes with many drawbacks (e.g. expensive, high carbon footprint, need dedicated facilities, trained personnel, and continuous monitoring and LN supply). Searching Nature for alternatives, long-term preservation there is done by drying rather than freezing. To date, however, mammalian cells do not survive the drying process. Even so, if somatic cells genetic and epigenetic load is maintained, drying can find an important role in biobanking, a fast growing global industry. We aim to elucidate the effects of drying on DNA structure and function, crucial aspects of long-term biobanking not investigated yet, using fibroblast as a model cell, and combining advanced freezing and drying techniques with state-of-the-art Somatic Cell Nuclear Transfer (SCNT) and latest genomic technologies. The expected outcomes are definitive data on effects of drying on genomic stability/function, and possible discovery of a protocol to protect the epi/genetic load during cell drying. The crossing between the Researcher’s scientific interest and experience in sperm biology, andrology, cryobiology and drying and the Supervisor’s expertise in embryology and SCNT creates an attractive and very solid background for this proposal, with mutual benefit to both Host and Researcher. While strengthening the Supervisor’s laboratory with his expertise, the Researcher will enhance his creative potential and further develop his interdisciplinary and communication skills by learning SCNT and whole genome analysis as well as mentoring students, participating in conferences, and communicating research results to targeted audiences (scientists, general public, students, stakeholders, policymakers), thus enhancing his scientific profile. This proposal is the perfect stepping stone for the Researcher to become an independent scientist and an expert in desiccation for biobanking, while contributing a competitive advantage to the Host.;180277,2;180277,2;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;UNIVERSITA DEGLI STUDI DI TERAMO;IT;;;;1;0;0;1;0;0 209143;724649;METROMOD;SIGNED;H2020-EU.1.1.;ERC-2016-COG;H2020;Relocating Modernism: Global Metropolises, Modern Art and Exile;2017-06-01;2022-05-31;;"Breaking new ground, METROMOD proposes a rewriting of modern art history as a history of global interconnections, spurred by migration movements and rooted in cities. Revising the historiography of modern art, which still continues to be dominated by the hegemonic and normative narratives of (Western) European Modernism and ignores the significance of exile movements, METROMOD conceptualizes art history as a result of interrelations and negotiations in global contact zones, unstable flows, transformations and crises. In its analysis, METROMOD focuses on the first half of the 20th century. During this era the modern movement emerged as a paradigm in art and architecture, and rapid urbanization took place globally; thousands of persecuted European modern artists fled their homes, re-establishing their practices in metropolises across the world. Reflecting both the geographical extent of these exile movements and their local urban impact METROMOD examines 6 key migrant destinations—the global cities of London, New York, Buenos Aires, Istanbul, Shanghai and Bombay (now Mumbai)—following three main objectives: to explore transformations in urban topographies, identifying artistic contact zones and places of transcultural art production; to investigate networks of exiled and local artists as well as collaborative projects and exhibitions; and to analyse art publications and discourse generated in centres of exile. Digital mapping will locate sites of artistic migration in the cities and demonstrate linkages between transforming metropolises and flows of people and objects around the world. The conceptual triangle of modernism, migration and the metropolis forms the foundation of an innovative comparative, interdisciplinary methodology. As well as impacting art history, METROMOD will provide a historical perspective from which today’s mass migration movements can be better understood.";1928400;1928400;ERC-2016-COG;/ERC-COG;LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN;DE;;;;1;0;0;1;0;0 210124;714033;MEDEA-CHART;SIGNED;H2020-EU.1.1.;ERC-2016-STG;H2020;The Medieval and Early Modern Nautical Chart: Birth, Evolution and Use;2017-06-01;2022-05-31;;Of all the technical and scientific developments that made possible the early modern maritime expansion, the nautical chart is perhaps the least studied and understood. This fact is very surprising as it was through those charts that the newly discovered world was first shown to the amazed eyes of the European nations. Although the History of Cartography is a well-established academic discipline and old charts have been examined for many years, their detailed technical study is still in its infancy. What is the origin of the pre-Mercator nautical chart, how charts evolved technically over time and how they were used at sea are all critical questions that remain to be answered. I intend to approach these challenges in a truly interdisciplinary way, by using innovative and powerful tools as a complement to the traditional methods of historical research: analytical cartometric methods, numerical modelling and the examination of the manuscripts through special lighting. By applying these tools to a large sample of charts of various periods and origins, I aim to unveil hidden graphic content related to their construction and use, to characterize their main geometric features, to establish meaningful connections with contemporary navigational methods and exploration missions, and to numerically simulate their construction by taking into account the explanations given in the textual sources. The effectiveness of those techniques has already been demonstrated in my previous studies, such as in the solution of an historical enigma which had been alive for more than a century: the construction of the Mercator projection, in 1569. Now, I propose to handle a broader and more complex set of questions, which has eluded the historians of cartography for even a longer period. The clarification of these issues will have a ground-breaking impact, not only in the strict field of the History of Cartography, but also in the context of the intellectual history at large.;1231319;1231319;ERC-2016-STG;/ERC-STG;FCIENCIAS.ID - ASSOCIACAO PARA A INVESTIGACAO E DESENVOLVIMENTO DE CIENCIAS;PT;;;;1;0;0;1;0;0 204439;679158;ResolutioNet;SIGNED;H2020-EU.1.1.;ERC-StG-2015;H2020;Resolving the Tussle in the Internet: Mapping, Architecture, and Policy Making;2017-02-01;2022-01-31;;"The Internet has revolutionalized the way people and corporations communicate, publish, access, and search for information. As our globally-connected digital civilization increasingly relies on its smooth operation any disruption has a direct negative impact on both the economy and society. However, the Internet was not designed to serve its current role nor was foreseen to be a public good. On the contrary, it was designed to be fully decentralized and thus administrated by the owners of independent networks. Today, the various Internet players have diverse and often conflicting objectives. Indeed, the tussle between Internet players or between them and governments hit the news and the negative externalities affect the life of potentially billions of Internet users worldwide and harm innovation in the Internet. We propose a research agenda to resolve the tussle in the Internet. First, we propose the use of sophisticated techniques to collect and analyze massive network data to unveil the complex interactions among the various Internet players that lead to disputes and to identify the conditions under which conditions a resolution is possible. Second, we utilize additional degrees of freedom to resolve the tussle in the Internet by enabling coordination of the various Internet players. To this end, we introduce expressiveness of all the involved parties in existing and emerging protocols and enable agile deployment of third-party services and applications inside operational networks. Third, we contribute to the Internet policy making debate by providing an unbiased view of the state and health of the Internet as well as providing recommendations on how to resolve the Internet tussle. This is an interdisciplinary effort to foster a dialogue for Internet's future and sustainability in light of its ever-increasing growth and competitiveness.";1499875;1499875;ERC-2015-STG;/ERC-STG;TECHNISCHE UNIVERSITAT BERLIN;DE;;;;1;0;0;1;0;0 203092;707624;PHOSPHOTRAC;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Speciation, sources, and fate of atmospheric organic phosphorus over the Mediterranean Sea: A missing piece of the P cycle?;2016-09-01;2018-08-31;;Phosphorus is a critical nutrient affecting primary productivity in large areas in oceanic ecosystems. The principal source of externally supplied nutrients in many marine ecosystems is the atmospheric deposition. As the ocean is an important sink of atmospheric CO2, phosphorus through productivity limitation can indirectly affect global warming by removing more CO2 from the atmosphere. The importance of organic P as a potential pool of bioavailable P in the atmosphere is not widely recognized. It is important to note that the only available data in the literature are the atmospheric measurements of phosphate and total phosphorus, while there are almost no data about the organic P, especially over Mediterranean Sea (MS). The main goal of PHOSPHOTRAC is to shed light on the atmospheric organic P chemical identification and to test the hypothesis that the increased acidification of the atmosphere may significantly impact the bioavailability of organic P. PHOSPHOTRAC proposes new methodologies and modern instrumentation for the identification of organic P compounds in the atmosphere. Most of them are implemented for the first time in atmospheric samples, and they will provide new insights into a nutrient cycle of P in MS. Organic P-rich compounds of interest are DNA, RNA, ATP, phytic acid, phospholipids, degradation products of chemical weapons, organophosphate ester flame retardants and organophosphorous pesticides. Further identification of atmospheric organic P sources in the region will be performed by using the chemical analysis data of specific tracers (ergosterol, anhydrosugars, trace metals), with statistical analysis, and implementation of atmospheric transport model TM4-ECPL coupled with the thermodynamic model ISORROPIA-II. The proposed project is highly interdisciplinary as it combines analytical chemistry, biology, and atmospheric modeling in order to address a question of extreme ecological importance related to climate change in the MS.;185076;185076;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;UNIVERSITE D'AIX MARSEILLE;FR;;;;1;0;0;1;0;0 199798;678812;OXYGEN;SIGNED;H2020-EU.1.1.;ERC-StG-2015;H2020;Quantifying the evolution of Earth's atmosphere with novel isotope systems and modelling;2016-06-01;2021-05-31;;Atmospheric oxygen is fundamental to life as we know it, but its concentration has changed dramatically over Earth’s 4.5 billion year history. An amazing qualitative story has emerged, in which Earth’s atmosphere was devoid of free oxygen for the first 2 billion years of planetary history, with two significant increases in concentration at ~2.4 and ~0.55 billion years ago. Both oxygenation events were accompanied by extreme climatic effects – the “snowball earth” episodes – and paved the way for massive reorganization of biogeochemical cycles such as the Cambrian radiation of macroscopic life. Despite these profound influences on the Earth system, we currently lack fundamental quantitative constraints on Earth’s atmospheric evolution. I am poised to add substantial quantitative rigor to Earth’s atmospheric history, by constraining the concentrations of important gases (e.g., O2, O3, CO2, CH4, organic haze) in ancient atmospheres to unprecedented accuracy. I will accomplish this via an innovative interdisciplinary program focused on the unusual mass-independent isotope fractionations observed in sedimentary rocks containing sulfur and oxygen. These signals are direct remnants of ancient atmospheric chemistry, and contain far more information than can currently be interpreted. This project combines novel experimental and methodological approaches with state-of-the-art numerical modelling to significantly advance our ability to decipher the isotope records. A unique “early Earth” UV lamp coupled to a custom-built photocell will enable direct production of isotope signals under Earth-like conditions, with time-dependent sampling. Groundbreaking analytical methodologies will vastly increase the global geochemical database. The experimental results and data will provide ground-truth for next-generation atmospheric models that will constrain atmospheric composition and its feedbacks with the Earth-biosphere-climate system during key points in our planetary history.;1767455;1767455;ERC-2015-STG;/ERC-STG;THE UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS;UK;;;;1;0;0;1;0;0 197542;671627;ESCAPE;SIGNED;H2020-EU.1.2.2.;FETHPC-1-2014;H2020;Energy-efficient SCalable Algorithms for weather Prediction at Exascale;2015-10-01;2018-09-30;;"'ESCAPE will develop world-class, extreme-scale computing capabilities for European operational numerical weather prediction (NWP) and future climate models. The biggest challenge for state-of-the-art NWP arises from the need to simulate complex physical phenomena within tight production schedules. Existing extreme-scale application software of weather and climate services is ill-equipped to adapt to the rapidly evolving hardware. This is exacerbated by other drivers for hardware development, with processor arrangements not necessarily optimal for weather and climate simulations. ESCAPE will redress this imbalance through innovation actions that fundamentally reform Earth-system modelling. ESCAPE addresses the ETP4HPC SRA 'Energy and resiliency' priority topic, developing a holistic understanding of energy-efficiency for extreme-scale applications using heterogeneous architectures, accelerators and special compute units. The three key reasons why this proposal will provide the necessary means to take a huge step forward in weather and climate modelling as well as interdisciplinary research on energy-efficient high-performance computing are: 1) Defining and encapsulating the fundamental algorithmic building blocks ('Weather & Climate Dwarfs') underlying weather and climate services. This is the pre-requisite for any subsequent co-design, optimization, and adaptation efforts. 2) Combining ground-breaking frontier research on algorithm development for use in extreme-scale, high-performance computing applications, minimizing time- and cost-to-solution. 3) Synthesizing the complementary skills of all project partners. This includes ECMWF, the world leader in global NWP together with leading European regional forecasting consortia, teaming up with excellent university research and experienced high-performance computing centres, two world-leading hardware companies, and one European start-up SME, providing entirely new knowledge and technology to the field. '";3977952,5;3977952,5;H2020-FETHPC-2014;/RIA;EUROPEAN CENTRE FOR MEDIUM-RANGE WEATHER FORECASTS;UK;"NATIONAL UNIVERSITY OF IRELAND GALWAY;DANMARKS METEOROLOGISKE INSTITUT;DEUTSCHER WETTERDIENST;INSTITUT ROYAL METEOROLOGIQUE DE BELGIQUE;INSTYTUT CHEMII BIOORGANICZNEJ POLSKIEJ AKADEMII NAUK;NVIDIA SWITZERLAND AG;BULL SAS;LOUGHBOROUGH UNIVERSITY;METEO-FRANCE;EIDGENOESSISCHES DEPARTEMENT DES INNERN;OPTALYSYS";"IE;DK;DE;BE;PL;CH;FR;UK";;1;0;0;1;0;0 220539;828902;E.T.PACK;SIGNED;H2020-EU.1.2.1.;FETOPEN-01-2018-2019-2020;H2020;Electrodynamic Tether Technology for Passive Consumable-less Deorbit Kit;2019-03-01;2022-05-31;;The Low Work-function Tether (LWT) is a long conductive tape coated with a material that enhances thermionic and photoelectric electron emissions. It enables spacecraft to de-orbit and/or re-boost without the need for consumables. It interacts passively with its environment (ambient plasma, magnetic field and solar radiation) to exchange momentum with the planet’s magnetosphere. E.T.PACK aims at developing a proof of concept for LWTs by breaking through and combining the current frontier of knowledge in three fields: plasma physics, low work function material science and space tethers. These will be integrated into a deorbit kit and a flight simulator for mission analysis. The kit aims to reach Technology Readiness Level 4 and will have two modes of operation: as a fully passive LWT and as a conventional electrodynamic tether equipped with an active hollow-cathode (backup mode). A new coating process for the electride, C12A7 ([Ca24Al28O64]4\(4e-)), will be developed, and used to manufacture a LWT demonstrator. The C12A7 and its extraordinary properties will be also applied to the hollow cathode of the kit, which will include a novel deployment mechanism specifically designed for LWT applications. The complex current exchange of LWTs with the ambient plasma under space-charge-conditions will be studied theoretically, and used to develop accurate simulators. The theory-experiment comparisons will lead to a solid framework for LWT operation and constraints, including thermal, mechanical, optical, electrical, ATOX and UV resistance, and survivability. Hitherto impossible mission scenarios will be explored, thus opening up new horizons in space science and technology. These interdisciplinary activities, placed at the cutting edge of their fields and highly interdependent, make E.T.PACK a high-risk project. This is fully compensated by its potential impact: Europe being the first with access to a reversible in-space propulsion technology free of consumables.;3039977,5;2999999,87;H2020-FETOPEN-2018-2019-2020-01;/RIA;UNIVERSIDAD CARLOS III DE MADRID;ES;"ADVANCED THERMAL DEVICES S.L.;FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.;SENER INGENIERIA Y SISTEMAS S.A.;UNIVERSITA DEGLI STUDI DI PADOVA;TECHNISCHE UNIVERSITAET DRESDEN";"ES;DE;IT";;1;0;0;1;0;0 220702;819819;APOLLO;SIGNED;H2020-EU.1.1.;ERC-2018-COG;H2020;Advanced Signal Processing Technologies for Wireless Powered Communications;2019-07-01;2024-06-30;;"Wireless power transfer (WPT), pioneered by Tesla, is an idea at least as old as radio communications. However, on the one hand, due to health concerns and the large antenna dimensions required for transmission of high energy levels, until recently WPT has been limited mostly to very short distance applications. On the other hand, recent advances in silicon technology have significantly reduced the energy needs of electronic systems, making WPT over radio waves a potential source of energy for low power devices. Although WPT through radio waves has already found various short-range applications (such as the radio-frequency identification technology, healthcare monitoring etc.), its integration as a building block in the operation of wireless communications systems is still unexploited. On the other hand, conventional radio wave based information and energy transmissions have largely been designed separately. However, many applications can benefit from simultaneous wireless information and power transfer (SWIPT). The overall objective of the APOLLO project is to study the integration of WPT/SWIPT technology into future wireless communication systems. Compared to past and current research efforts in this area, our technical approach is deeply interdisciplinary and more comprehensive, combining the expertise of wireless communications, control theory, information theory, optimization, and electronics/microwave engineering. The key outcomes of the project include: 1) a rigorous and complete mathematical theory for WPT/SWIPT via information/communication/control theoretic studies; 2) new physical and cross-layer mechanisms that will enable the integration of WPT/SWIPT into future communication systems; 3) new network architectures that will fully exploit potential benefits of WPT/SWIPT; and 4) development of a proof-of-concept by implementing highly-efficient and multi-band metamaterial energy harvesting sensors for SWIPT.";1930625;1930625;ERC-2018-COG;/ERC-COG;UNIVERSITY OF CYPRUS;CY;;;;1;0;0;1;0;0 219178;823886;REFRACT;SIGNED;H2020-EU.1.3.3.;MSCA-RISE-2018;H2020;Repeat protein Function Refinement, Annotation and Classification of Topologies;2019-01-01;2022-12-31;;"The REFRACT proposal answers the RISE call, aiming at the promotion of an international and interdisciplinary collaboration on tandem repeat proteins (TRPs) through the sharing of knowledge and expertise between partners via staff exchanges. REFRACT is an international consortium aiming to extend our knowledge on the mechanism of TRP function and evolution, establishing a common classification and best practices. Starting from available state of the art computational tools and databases, which have been mostly developed by REFRACT participants, it aims drive a new level of TRP characterization leveraging the complementary expertise of 7 EU MS and 9 TC institutions in Latin America, with the latter providing useful complementary expertises. This aim will be achieved by the following steps: Benchmarking different existing methods and defining their use-cases; Coordinating the necessary next steps to analyze TRP roles in biological pathways and organism evolution; Providing a detailed description of their mechanism of function, related to their structural properties, that can be of great importance in TRP-related medical research and biotechnological applications; Building a unified and commonly accepted TRP classification from sequence and structure as well as characterizing the relationship between the two. The REFRACT implementation will take advantage of the different expertises, supporting them by a combination of research-centered, training and dissemination activities. The secondment program is designed so that all the participating institutions will be actively involved not only in the production of scientific outcomes, but also be empowered with the responsibility of planning, monitoring and discussing project advancement. The broadest possible dissemination of the results will be achieved through dedicated activities, the propagation of results into ELIXIR core data resources (InterPro, and consequently UniProt) as well as possible industrial exploitation.";2392000;2226400;H2020-MSCA-RISE-2018;/MSCA-RISE;UNIVERSITA DEGLI STUDI DI PADOVA;IT;"JOHANNES GUTENBERG-UNIVERSITAT MAINZ;EUROPEAN MOLECULAR BIOLOGY LABORATORY;AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;ZURCHER HOCHSCHULE FUR ANGEWANDTE WISSENSCHAFTEN;STOCKHOLMS UNIVERSITET";"DE;ES;FR;CH;SE";;1;0;0;1;0;0 195930;660343;SURFACE;CLOSED;H2020-EU.1.3.2.;MSCA-IF-2014-GF;H2020;Human-Landscape-Interactions and Global Dispersals: The SURFACE Record of Palaeolithic Arabia;2016-01-01;2018-06-30;;"SURFACE is an international, trans-disciplinary action combining approaches from archaeology, geomorphology and remote sensing to develop novel approaches to the analysis of the distribution of surface artefacts in arid landscapes. It will use these to address models of human-environment-landscape interactions in Palaeolithic Arabia and their implications for global dispersal of hominin populations. At a key crossroads of global dispersals, and with a proven but little-studied record of Palaeolithic occupation, Southwestern Saudi Arabia possesses a surface record vital to understanding Pleistocene dispersals out of Africa. How different Homo species (H. erectus, H. sapiens), utilised their landscapes, and subsequent implications for their abilities to disperse from Africa is poorly understood, and interpretation of past hominin landscape use from present-day artefact distributions is not straightforward. Distributions are the sum of varying behaviours over time, while landscape evolution alters the distribution and availability of resources linked to these behaviours (e.g. water, raw materials) and the preservation and visibility of archaeological evidence. It is only by developing a robust, well-dated model of landscape evolution, and detailed recording of surface artefacts in relation to the geomorphological units comprising the landscape, coupled with theoretical paradigms that engage with the variable time depth of surface assemblages that the potential of this record for informing on past hominin-landscape interactions can be realised. SURFACE brings together researchers from the UK and Australia at the cutting edge of developing approaches to the surface record. It will train the ER in these interdisciplinary methods to enable her to fully exploit the globally significant Palaeolithic record of SW Saudi Arabia, and to further develop methodological and theoretical approaches to the surface record, with implications far beyond the time period in question.";216512,4;216512,4;H2020-MSCA-IF-2014;/MSCA-IF-GF;UNIVERSITY OF YORK;UK;;;;1;0;0;1;0;0 194584;649456;ENLIGHTEN;CLOSED;H2020-EU.3.6.;EURO-4-2014;H2020;European Legitimacy in Governing through Hard Times: the role of European Networks;2015-04-01;2018-03-31;;ENLIGHTEN responds to the first part of the EURO-4 call on “The future of European integration - 'More Europe – less Europe?'” by bringing together an interdisciplinary ‘next generation’ research team that integrates insights from Comparative Political Economy, European Studies, International Political Economy, and Sociology. ENLIGHTEN answers the call by focusing on how European modes of governance respond to ‘fast-burning’ and ‘slow-burning’ crises. These types of crises differ in how they affect the legitimacy of European input, output, and throughput processes in established and emergent modes of governance. In fast-burning crises interests are quickly formed and ideational and resource battles ensue over how to coordinate policy ideas, what institutions should be engaged, and communicating these changes to the public. Networks in fast crises are composed of defined groups seeking to protect or carve out their interests. In slow-burning crises interests are less obvious and the key task is often how to define the issues involved and who should address the problem. Here networks are commonly composed of experts who battle over how issues should be defined, as well as the boundaries on how coordinative and communicative discourses are articulated. Both fast- and slow-burning crises must be addressed by European modes of governance, with serious implications for the legitimacy and efficiency of the European project. Both raise political, social, and economic sensitivities that are transforming democratic politics in Europe. ENLIGHTEN addresses these themes through a series of linked cases that speak directly to the legitimacy and efficiency of European modes of governance.;2484111,25;2484111;H2020-EURO-SOCIETY-2014;/RIA;COPENHAGEN BUSINESS SCHOOL;DK;"COMITE EUROPEEN DE COORDINATION DE L'HABITAT SOCIAL AISBL;TAX JUSTICE NETWORK LIMITED;KOZEP-EUROPAI EGYETEM;FINANCE WATCH AISBL;UNIVERSITE LIBRE DE BRUXELLES;CONFEDERATION EUROPEENNE DES SYNDICATS ADF;UNIVERSITEIT VAN AMSTERDAM";"BE;UK;HU;NL";;1;0;0;1;0;0 210331;752790;WESTRAT;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Western Strategies in East Asia. The Reconfiguration of US, British and French security policies in the Pacific Century;2017-09-01;2020-09-08;;The core question that this project tackles is how the three major Western military powers (the US, Britain and France) have adapted their security policies to the shifting center of strategic gravity of international politics from the Euro-Atlantic area to the Asia-Pacific. In addressing this question, WESTRAT conducts a comparative analysis of their evolving security policies in confronting the main “traditional” and “non-traditional” security challenges in East Asia, i.e. the rise of China, the proliferation of weapons of mass destruction and piracy. In so doing, this project makes three original contributions. (1) Firstly, WESTRAT offers an empirical contribution as the first work to provide a cross-national comparison of the security policies of the three major Western powers (1990-2016) – in their national, bilateral, and multilateral configurations – in what is deemed to be the world’s new center of strategic gravity. It therefore investigates a crucial yet under-explored dimension of contemporary international politics. (2) Secondly, it provides an innovative conceptual framework that sheds light on the emerging networks of national, bilateral and multilateral security arrangements (what we label “networked security postures”) in international politics. It thereby contributes to the debates on the under-theorized relationships between bilateralism and multilateralism as venues for security cooperation. (3) Finally, given the absence of a common European strategy toward the region, this project seeks to enrich the policy discussions in the European Union (EU) and to provide policy recommendations on how to bolster cooperation between the EU, its member states, and the US – and transatlantic relations more generally – in developing a common strategy towards the (re)emergence of East Asia in world politics. Combining concepts and methods derived from international relations, from sociology, and from history, WESTRAT takes an interdisciplinary perspective.;168277,2;168277,2;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;EUROPEAN UNIVERSITY INSTITUTE;IT;;;;1;0;0;1;0;0 205566;722028;ENIGMA;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2016;H2020;European training Network for In situ imaGing of dynaMic processes in heterogeneous subsurfAce environments;2017-01-01;2020-12-31;;The ENIGMA network will train a new generation of young researchers in the development of innovative sensors, field survey techniques and inverse modelling approaches. This will enhance our ability to understand and monitor dynamic subsurface processes that are key to the protection and sustainable use of water resources. ENIGMA focuses mainly on critical zone observation, but the anticipated technological developments and scientific findings will also contribute to monitor and model the environmental footprint of an increasing range of subsurface activities, including large-scale water abstraction and storage, enhanced geothermal systems and subsurface waste and carbon storage. While many subsurface structure imaging methods are now mature and broadly used in research and practice, our ability to resolve and monitor subsurface fluxes and processes, including solute transport, heat transfer and biochemical reactions, is much more limited. The shift from classical structure characterization to dynamic process imaging, driven by ENIGMA, will require the development of multi-scale hydrogeophysical methods with adequate sensitivity, spatial and temporal resolution, and novel inverse modelling concepts. For this, ENIGMA will gather (i) world-leading academic teams and emerging companies that develop innovative sensors and hydrogeophysical inversion methods, (ii) experts in subsurface process upscaling and modelling, and (iii) highly instrumented field infrastructures for in-situ experimentation and validation. ENIGMA will thus create a creative and entrepreneurial environment for trainees to develop integrated approaches to water management with interdisciplinary field-sensing methods and novel modelling techniques. ENIGMA will foster EU and international cooperation in the water area by creating new links between hydrogeological observatories, academic research groups, innovative industries and water managers for high-level scientific and professional training.;3865769,64;3865769,64;H2020-MSCA-ITN-2016;/MSCA-ITN-ETN;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FR;"UNIVERSITE DE LIEGE;UNIVERSITE DE LAUSANNE;FORSCHUNGSZENTRUM JULICH GMBH;ITASCA CONSULTANTS;HELMHOLTZ-ZENTRUM FUR UMWELTFORSCHUNG GMBH - UFZ;KOBENHAVNS UNIVERSITET;AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS;UNIVERSITE DE NEUCHATEL;MUQUANS;EBERHARD KARLS UNIVERSITAET TUEBINGEN";"BE;CH;DE;FR;DK;ES";;1;0;0;1;0;0 203184;713683;COFUNDfellowsDTU;SIGNED;H2020-EU.1.3.4.;MSCA-COFUND-2015-FP;H2020;H.C. ?rsted Fellows Programme – co-funded by Marie Sk³odowska Curie Actions (COFUNDfellowsDTU);2017-01-01;2021-12-31;;"With the H.C. ?rsted Fellows Programme – co-funded by Marie Sk³odowska Curie Actions (COFUNDfellowsDTU) DTU will attract highly talented young researchers through incoming mobility from around the world. The Programme takes place at the Technical University of Denmark (DTU) which is a top ranked university with focus on all Engineering Sciences as well as Life Science and Biotechnology. The Programme will provide uninterrupted continuity of the existing and highly successful co-funded Programme and introduce new improvements by offering both junior and senior fellowships, increase the number of fellowship years to 126, introduce effective career development and increase focus on industrial secondment and exploitation of innovative research results. Fellows will have the opportunity to shape their careers within the world-leading innovative environment at DTU, by engaging in curiosity-driven, bottom-up research according to their own choice within all available branches of engineering science. The Programme will introduce the opportunity of a 3 months secondment in industry, and implement the triple I – international, interdisciplinary and intersectoral exposure. This will prime fellows for careers in both academia and industry, and put innovation at the centre of the Programme. Grants will be awarded in open, international competition. The selection of successful proposals will be carried out in a process comprising the following three steps: 1) International peer review of each application by three reviewers, 2) Rebuttal to peer review from applicants and 3) Final decision on the award of fellowships by the DTU Selection Committee. DTU will ensure equal opportunity and introduce anonymisation of applicants' names and gender during the review process. The Programme is open to all interested candidates regardless of sex, age, ethnicity, religion and sexuality.";8920800;4460400;H2020-MSCA-COFUND-2015;/MSCA-COFUND-FP;DANMARKS TEKNISKE UNIVERSITET;DK;;;;1;0;0;1;0;0 195146;655653;KinCoop;CLOSED;H2020-EU.1.3.2.;MSCA-IF-2014-GF;H2020;Do plants cooperate in reproduction? The effect of sharing pollination services on plant reproductive strategies;2015-08-01;2018-07-31;;"Although social interactions in non-sentient beings such as plants might seem unlikely, there are good reasons to expect them to be important. Because plant populations are very often strongly genetically structured, with neighbouring plants frequently being relatives, their behaviour is expected to have been shaped by natural selection within this social context. Plants interact very strongly with their neighbours, and there is an increasing body of evidence showing kin recognition and cooperation with relatives, e.g., warning against herbivore attacks and reducing resource competition. However, little is known about how plants behave in a social context in terms of their reproductive strategies. This is surprising, because reproduction is a key life-history trait defining gene transfer, and thus is closely linked to fitness and to the evolutionary potential that will eventually determine the functioning and dynamics of plant populations and communities. Neighbouring plants commonly facilitate pollination. Therefore, the resources invested in floral attractive structures for one individual can positively impact individual fitness, but also the fitness of neighbours, increasing both individual and group benefits. Thus, natural selection should be expected to favour plastic adjustments of the resources allocated to pollinator attraction to the surrounding social environment. I will test this hypothesis, assessing how different social environments might influence optimal allocation strategies and the effect this will have on mating patterns and plant fitness. To address this objective, I will use an interdisciplinary approach that combines theoretical modelling and empirical testing, bringing tools from the sociological sciences to the study plant ecology and evolution. My project will contribute to our understanding of how plants cooperate during reproduction to alter plant population dynamics, with potentially useful outcomes for crop efficiency.";272480,4;272480,4;H2020-MSCA-IF-2014;/MSCA-IF-GF;AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS;ES;;;;1;0;0;1;0;0 220682;819227;FUMI;SIGNED;H2020-EU.1.1.;ERC-2018-COG;H2020;Future Migration as Present Fact;2019-07-01;2024-06-30;;The springboard for this project is a striking statistic: half of all young adults in West Africa wish to leave their own country and settle elsewhere. Yet, the vast majority never depart. This discrep-ancy raises a fundamental question: if migration is desired, but never materializes, what are the consequences? The project breaks with traditional approaches by shifting the object of study from observed migration in the present to imagined migration in the future. Although such future migration might never occur, it materializes in thoughts, feelings, communication, and behaviour at present. Young people’s priorities are informed by the futures they imagine, and their lives can thus be formed by migration that is imagined but never achieved. Framing the issue in this way renews research on the precursors of migration and opens up a new chapter about the links be-tween migration and development. The project is guided by a bold central hypothesis: Migration that is imagined, yet never takes place, decisively shapes the lives of individuals and the devel-opment of societies. This hypothesis is addressed through a research design that weaves together three streams: theory development, ethnographic fieldwork, and sample surveys. Drawing upon the PI’s proven qualifications in all three fields, the project aims for deep mixed-methods integra-tion. The project’s empirical focus is West Africa. Migration desires are particularly widespread in this region, and internal socio-economic variation can be exploited for theoretical purposes. By investing in theoretical and methodological development, attuned to a poorly understood aspect of global migration challenges, the project holds the promise of sustained impacts on migration research. The project is set within interdisciplinary migration studies, anchored in human geogra-phy and supported by related disciplines including anthropology, economics, and sociology.;1999672;1999672;ERC-2018-COG;/ERC-COG;INSTITUTT FOR FREDSFORSKNING STIFTELSE;NO;;;;1;0;0;1;0;0 220673;817791;LHCtoLISA;SIGNED;H2020-EU.1.1.;ERC-2018-COG;H2020;Precision Gravity: From the LHC to LISA;2019-06-01;2024-05-31;;"The nascent field of gravitational wave (GW) science will be an interdisciplinary subject, enriching different branches of physics, yet the associated computational challenges are enormous. Faithful theoretical templates are a compulsory ingredient for successful data analysis and reliable physical interpretation of the signals. This is critical, for instance, to study the equation of state of neutron stars, the nature of black holes, and binary formation channels. However, while current templates for compact binary sources may be sufficient for detection and crude parameter estimation, they are too coarse for precision physics with GW data. We then find ourselves in a situation in which, for key processes within empirical reach, theoretical uncertainties may dominate. To move forward, profiting the most from GW observations, more accurate waveforms will be needed. I have played a pioneering role in the development and implementation of a new formalism, known as the ‘effective field theory approach’, which has been instrumental for the construction of the state-of-the-art GW template bank. The goal of my proposal is thus to redefine the frontiers of analytic understanding in gravity through the effective field theory framework. Even more ambitiously, to go beyond the current computational paradigm with powerful tools which have been crucial for `new-physics' searches at the Large Hadron Collider. The impact of the high-accuracy calculations I propose to undertake will be immense: from probes of dynamical spacetime and strongly interacting matter, to the potential to discover exotic compact objects and ultra-light particles in nature. Furthermore, GW observations scan gravity in a regime which is otherwise unexplored. Consequently, the coming decade will tell whether Einstein's theory withstands precision scrutiny. In summary, my program will provide novel techniques and key results that will enable foundational investigations in physics through GW precision data.";1975000;1975000;ERC-2018-COG;/ERC-COG;STIFTUNG DEUTSCHES ELEKTRONEN-SYNCHROTRON DESY;DE;;;;1;0;0;1;0;0 220681;819511;METAFOAM;SIGNED;H2020-EU.1.1.;ERC-2018-COG;H2020;Novel assembly strategies in liquid dispersion via interface control – towards cellular metamaterials;2019-05-01;2024-04-30;;"The astounding properties of metamaterials result from a characteristic spatial organisation of purpose-designed structural units. Research on metamaterials has greatly advanced thanks to their reliable top-down fabrication (lithography, 3D-printing,...). For large-scale production, however, smart bottom-up design strategies are required, for example through self-assembly of the structural units. While this has been developed for thermally-driven systems with sub-micrometric units, no systematic design strategies are established for mechanically-driven systems with larger units. The METAFOAM project will fill this gap by addressing the scientific challenges towards controlled bottom-up structuring of bubble/drop packings in liquid foam/emulsion templates. While “ordinary” foams/emulsions have been investigated in depth, the control over their structure is very limited. The METAFOAM project will provide access to very different structures by explicitly tuning the bubble/drop interactions through the presence of a polymeric skin with controlled repulsive, adhesive and frictional properties. We will develop methods to reliably create/characterise these skins and establish a state diagram which systematically relates the resulting bubble/drop interactions and the foam/emulsion structure. Solidification of the most promising structures will provide new types of cellular polymers with currently inaccessible mechanical or acoustic meta-properties: high stiffness-to-weight-ratios, negative Poisson ratios, and acoustic band-gap properties. The impact of this interdisciplinary project at the interface between physics and chemistry is therefore two-fold. In the liquid state it will advance our understanding of the a-thermal packing of very soft objects with tuneable interactions, linking the physics of granular media and biological tissues. In the solid state it will provide new cellular systems for the fabrication and investigation of mechanical and acoustic metamaterials.";1999677;1999677;ERC-2018-COG;/ERC-COG;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FR;;;;1;0;0;1;0;0 212785;759207;P2PMODELS;SIGNED;H2020-EU.1.1.;ERC-2017-STG;H2020;Decentralized Blockchain-based Organizations for Bootstrapping the Collaborative Economy;2018-01-01;2022-12-31;;"The Collaborative Economy (CE) is rapidly expanding through new forms of Internet labor and commerce, from Wikipedia to Kickstarter and Airbnb. However, it suffers from 3 main challenges: (1) Infrastructure: centralized surveillance that the central hubs of information exercise over their users, (2) Governance: disempowered communities which do not have any decision-making influence over the platform, and (3) Economy: concentration of profits in a few major players who do not proportionally redistribute them to the contributors. How can CE software platforms be implemented for solving these challenges? P2PMODELS explores a new way of building CE software platforms harnessing the blockchain, an emerging technology that enables autonomous agent-mediated organizations, in order to (1) provide a software framework to build decentralized infrastructure for Collaborative Economy organizations that do not depend on central authorities, (2) enable democratic-by-design models of governance for communities, by encoding rules directly into the software platform, and (3) enable fairer value distribution models, thus improving the economic sustainability of both CE contributors and organizations. Together, these 3 objectives will bootstrap the emergence of a new generation of self-governed and more economically sustainable peer-to-peer CE communities. The interdisciplinary nature of P2PMODELS will open a new research field around agent-mediated organizations for collaborative communities and their self-enforcing rules for automatic governance and economic rewarding. Bringing this proposal to life requires a funding scheme compatible with a high-risk/high-gain vision to finance a fully dedicated and highly motivated research team with multidisciplinary skills.";1498855;1498855;ERC-2017-STG;/ERC-STG;UNIVERSIDAD COMPLUTENSE DE MADRID;ES;;;;1;0;0;1;0;0 212229;778357;SMARTELECTRODES;SIGNED;H2020-EU.1.3.3.;MSCA-RISE-2017;H2020;Multiscaled Smart Metallic and Semiconductor Electrodes for Electrochemical Processing and Devices;2018-01-01;2021-12-31;;"Demand of “smart” electrodes/systems has recently increased due to significant role of various devices/equipment based on these electrodes - urgent needs of present and forthcoming human activities. The multi- and interdisciplinary project SMARTELECTRODES is proposing elaboration of advanced systems covered under umbrella of “smart” electrodes which will be involved and play significant roles in several important electrochemical/electrophysical applications as catalysis/electrocatalysis, sensoring, thermoelectrics, electrowinning, electrochemical machining and electrospark alloying. The development of multiscaled (from nano- to macro-; from nanodot to volumized 3D-) metallic and semiconductor electrodes and integration of them into working systems/equipment is the main target of SMARTELECTRODES. The project is well-balanced, highly innovative R&D training network, which aims: To develop long lasting collaborations between four academic (Vilnius University, Lithuania; Institute of Applied Physics, Moldova; Northeastern University, USA; Research Institute for Physical Chemical Problems of BSU, Belarus) and two companies (JSC Topaz, Moldova and JSC “Electronics Treatment Technologies”, EPT, Lithuania); To develop new electrodes (based on chalcogenides, iron group metals and “technological” electrodes) by well-established institutions; To increase career perspectives of each participant that will lead to benefit of each member and partnership as a whole. Partners will be complimentary involved into realization of the proposed research. The research tasks will be implemented through multidisciplinary Work Packages devoted to the fabrication, adapting and investigation of electrodes/materials, also they include the activities towards training and management. Namely, advanced training will be provided to the seconded staff through well-integrated programs, including workshops and conferences.";684000;598500;H2020-MSCA-RISE-2017;/MSCA-RISE;VILNIAUS UNIVERSITETAS;LT;"Institute of Applied Physics of the Academy of Sciences of Moldova;ELEKTRONIKOS PERDIRBIMO TECHNOLOGIJOS UAB;INTREPRINDEREA MIXTA UZINA TOPAZ SA";"MD;LT";;1;0;0;1;0;0 211744;765657;SAFER;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2017;H2020;Selective Agonists For Serotonin Receptors;2017-09-01;2021-08-31;;"SAFER will train 5 ESRs, PhD students, to obtain ample scientific, business and transferrable skills, arming them with the expertise to translate knowledge into products and services with importance for European industry and society. All ESRs will first train together at one university to develop complementary skills and basic research data; and subsequently move to two SMEs for applied and commercial research. The ultimate scientific goal for the SAFER program is to gain molecular understanding and improve selectivity in treatments of CNS-related disorders. This will be done through an interdisciplinary and intersectoral approach, building on a strong complementarity between partners, with a particular focus on the serotonin 5-HT2A receptor – the primary target for many pharmaceuticals and hallucinogens. SAFER will generate and cross-interpret pharmacology and crystallographic data, and construct computational mechanistic models and databases that can explain and guide its experiments. Thus, SAFER will gain new insights into molecular mechanisms that are fundamental to understand the biological and therapeutic effects, and to develop safer drugs. SAFER ESRs will be highly competitive on the job market and much in demand. In particular, crystallography and biased signalling pharmacology of G protein-coupled receptors (e.g. 5-HT2A) are new and highly active research fields, today mastered by only a very few research groups worldwide. The timing and location of SAFER are particularly opportune, taking advantage of the new synchrotron MAX IV in Lund, Sweden, which is world leading for the study of challenging crystals. SAFER will seek to exploit innovation opportunities from novel molecular mechanisms, ligands, and crystal structures. The results will be integrated into a public community resource, GPCRdb, giving a unique potential to achieve community impact and long-term sustainability.";1286630,94;1286630,94;H2020-MSCA-ITN-2017;/MSCA-ITN-EID;KOBENHAVNS UNIVERSITET;DK;"SAROMICS BIOSTRUCTURES AB;ENAMINE LIMITED LIABILITY COMPANY,RESEARCH AND PRODUCTION ENTERPRISE";"SE;UA";;1;0;0;1;0;0 209084;753816;VIVIR;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;VIsual representations of VIew Relations to support effective data analysis on large and high-resolution displays;2017-10-01;2020-09-30;;"In VIVIR, I will conduct state-of-the-art research on supporting collaborative face-to-face data analysis. This is motivated by the increasing need for interdisciplinary teams to collaborate on understanding and analysing data. Additionally, as the scale and complexity of data increase, so does the demand for data-based insights and decision-making. My approach is to empower people who are working with large and complex data, by letting them lay out as many visualization views (in the following, denoted views) as necessary on large displays, and creating specialized meta-visualizations to show relations between these views. These meta-visualizations will allow team workers to be aware of each other’s work and the changing view- and data-relationships as they work. While the potential of view meta-visualizations has been acknowledged , there are currently only a few frequently used and considered essential examples of such meta-visualizations. These might show that data in two views are compared in a third view, or that a view shows a subset of the data shown in another view. Most importantly, there has been no thorough exploration into the power and potential of meta-visualization support for data-driven decision-making. To understand the potential impact of meta-visualizations on data analysis, we need to take a structured approach, to formalize these possibilities, which will improve our abilities to support knowledge worker teams as they face the challenges of analyzing increasingly complex data. In brief, data can be difficult to understand. Creating visualizations of data lets people see their data more clearly. As data size and complexity increases, more views are needed to reveal the information hidden in data. Large displays might be useful to solve this. However, a new problem is emerging – how to be aware of the data relationships, and keep an overview of analysis provenance , findings, and decisions between these multiple views. VIVIR tackles this issue.";263719,8;263719,8;H2020-MSCA-IF-2016;/MSCA-IF-GF;KOBENHAVNS UNIVERSITET;DK;;;;1;0;0;1;0;0 207208;732386;TreatER;SIGNED;H2020-EU.3.1.3.;SC1-PM-09-2016;H2020;"Clinical study in Parkinson's disease with two unique goals: 1) Proof-of-concept of CDNF protein for disease modification; 2) Validation of clinically tested device for intracerebral drug delivery";2017-01-01;2019-12-31;;"The main focus of TreatER is conducting a randomized, placebo-controlled, first-in-human, proof-of-concept, safety and efficacy study of intracerebrally administered CDNF protein therapy in patients with Parkinson’s disease (PD), using a neurosurgically implanted Drug Delivery System (DDS), which will also be clinically validated in the study. Thus the TreatER project has two independent goals, either of which alone can have significant impact addressing unmet clinical needs in chronic diseases, and advancing innovative European technologies: 1) Proof-of-concept of CDNF protein therapy for disease modification in PD. The patented European innovation CDNF has further potential in other ER stress related indications. 2) Clinical validation of DDS, an already clinically tested approach for accurately targeted intracerebral infusions in PD. The patented European innovation DDS has also significant potential in other indications needing intracerebral infusions. The clinical study builds on extensive preclinical research and related data on CDNF, including completed acute and chronic toxicology studies in non-human primates supporting an excellent safety profile. Further, the clinical study builds on existing clinical experience on DDS and related neurosurgery. Both conventional and novel means for assessing the efficacy of the treatment will be utilized. This requires strong interdisciplinary expertise and knowledge available in the consortium, including: Regulatory expertise in drug and medical device development; neurological and neurosurgical expertise in PD; PET imaging expertise specific to PD; Scientific expertise in novel neurotrophic factors, in specific CDNF; and GMP manufacturing expertise of novel biological drug compounds. Clinical trial applications are currently being submitted in Finland and Sweden, in accordance with previously obtained scientific advice from regulatory authorities in those countries as well as from MHRA (UK) and EMA's ITF.";8705549,75;5971173,75;H2020-SC1-2016-RTD;/RIA;HELSINGIN YLIOPISTO;FI;"HELSINGIN JA UUDENMAAN SAIRAANHOITOPIIRIN KUNTAYHTYMÄ;RENISHAW PLC;ORION OYJ;ASSOCIATION EUROPEENNE POUR LA MALADIE DE PARKINSON;H. LUNDBECK AS;KAROLINSKA INSTITUTET;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;STOCKHOLMS LANS LANDSTING;SKANE LANS LANDSTING;HERANTIS PHARMA OYJ";"FI;UK;BE;DK;SE";;1;0;0;1;0;0 204114;680002;HBIS;SIGNED;H2020-EU.1.1.;ERC-StG-2015;H2020;The Human Behavioral Immune System: Consequences for Health and Innovation;2016-07-01;2021-06-30;;Modern innovations such as soap, condoms, and indoor plumbing have allowed billions of people to reduce their contact with viruses and bacteria and, as a result, dramatically increase length and quality of life. But how did members of the genus homo avoid pathogens for the two million years that preceded these technological innovations and, more broadly, discoveries that infectious disease is caused by microbes? And, importantly, how do any natural behavioral defenses against pathogens impact our behavior in the modern world? Recent research and theory in the field of evolutionary psychology suggests that natural selection has shaped a human behavioral immune system (HBIS)—a suite of psychological mechanisms, ranging from aspects of our olfactory systems (e.g., that detect specific chemical compounds) to our emotion systems (e.g., the emotion disgust) and our learning systems (e.g., conditioned aversions to foods) that are coordinated for a common function: to detect and motivate the avoidance of pathogens. Given that myriad universal human behaviors connote some pathogen risk—including interpersonal contact, mating, and eating—gaining a holistic understanding of the HBIS has the potential to offer critical new insights into multiple fundamental aspects of human nature. Here, I utilize an interdisciplinary approach to answer three foundational, yet currently opaque questions concerning the nature of the HBIS, including: (1) Where does trait variation in HBIS activation come from? (2) What effect does the HBIS have on behavior when cues to pathogens are detected? and (3) How does the HBIS facilitate learning of avoidance and rejection? To answer these questions, I propose an array of methodologically diverse studies to investigate how trait HBIS activation shapes rejection versus acceptance of innovations, how state HBIS activation can be harnessed to promote the use of health-promoting technologies, and how the HBIS can be leveraged for shaping dietary behavior.;1499482,5;1499482,5;ERC-2015-STG;/ERC-STG;STICHTING VU;NL;;;;1;0;0;1;0;0 198271;675111;EVOluTION;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2015-ETN;H2020;European Vascular Interventions and Therapeutic Innovation Network;2016-04-01;2020-03-31;;"EVOluTION, a pioneering network within EU in view of its focus on endogenous protective mechanisms, is formed to provide training for 11 young researchers in innovative therapeutic strategies, integrating early detection and prevention, to yield novel approaches to the management of chronic vascular and metabolic diseases that affect the increasing ageing population of Western societies. Fully aligned with the knowledge triangle (business, research and higher education) platform being developed at the EU level, EVOluTION-trained young scientists will gain valuable knowledge and multidisciplinary skills: only interdisciplinary and cross-cutting research can lead to novel therapeutic tools and scientific angles to address these challenging medical, societal and industrial issues. EVOluTION provides a conducive structure by bringing 5 leading academic institutions and 1 SME, together with 6 Pharma and biotech companies, 1 Policy-maker, and 1 Patent & Trade firm as Partner Organisations, from 6 EU countries. The science of EVOluTION evolves around the innovative concept of boosting natural protective mechanisms operating in our body, focusing on the vasculature, to answer 3 key questions: Can we exploit mediators and targets of endogenous tissue protection? Can we exploit these pathways to yield innovative therapeutic strategies? Can dietary approaches boost these endogenous protective processes? The Network Partners guarantee delivery of training through knowledge creation, knowledge exploitation and knowledge communication. Scientific and educational expertise of the partners, leaders in areas like computational chemistry, nutraceuticals, resolution pharmacology and vascular therapies will be maximally exploited. The EVOluTION training platform is based on state-of-the-art lab-based and network-wide and local training activities, including secondments and scientific visits and specialized transferable skills focussed in entrepreneurship and societal engagement.";2887041,24;2887041,24;H2020-MSCA-ITN-2015;/MSCA-ITN-ETN;QUEEN MARY UNIVERSITY OF LONDON;UK;"LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN;UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN;LIFEARC;UNIVERSITEIT MAASTRICHT;KAROLINSKA INSTITUTET";"DE;IE;UK;NL;SE";;1;0;0;1;0;0 197230;638154;EUTHORITY;SIGNED;H2020-EU.1.1.;ERC-StG-2014;H2020;Conflict and Cooperation in the EU Heterarchical Legal System;2015-09-01;2020-08-31;;Supranational legal regimes are increasingly enforced by multi-level, non-hierarchical court systems, in which judges at the upper, supranational echelon do not have the power to reverse domestic court decisions. Yet the incentives and dynamics that shape the complex patterns of conflict and cooperation observed in the most important of all such court structures, the EU legal system, are still poorly understood. To what extent are domestic courts able to negotiate the terms of their cooperation with the Court of Justice? How do national courts differ in that respect? Are the non-compliance threats issued by domestic courts all equally credible? Do the rare cases where these threats have been put to execution pose a systemic risk to the authority of EU law? How are the domestic courts’ incentives to cooperate with EU judges affected by the sort of political backsliding witnessed in Hungary and Romania in recent years? Our interdisciplinary research project addresses these puzzles of legal integration with the avowed aim of helping judges and policy-makers make more informed choices when faced with compliance problems in the judicial realm. Grounded in a general theory of judicial behaviour, our generic hypothesis is that the authority of EU law at domestic level is determined by domestic politics as well as by judicial attitudes towards integration. EUTHORITY seeks to refine this hypothesis using game theoretic modelling to analyse strategic interactions among the Court of Justice and domestic courts and politicians. Theory-building combines with a large-scale data-collection effort. We undertake to compile longitudinal data on the institutional characteristics and doctrinal responses to legal integration of 68 domestic apex courts across the EU 28 Member States. With a view to construct an annual, court-specific index of legal integration, we also conduct an expert survey asking academic lawyers and practitioners to assess their courts' attitudes towards EU law.;1475150;1475150;ERC-2014-STG;/ERC-STG;KATHOLIEKE UNIVERSITEIT LEUVEN;BE;;;;1;0;0;1;0;0 193869;641999;ProSUM;CLOSED;H2020-EU.3.5.4.;WASTE-4c-2014;H2020;Prospecting Secondary raw materials in the Urban mine and Mining waste;2015-01-01;2017-12-31;;"The ProSUM project will establish a European network of expertise on secondary sources of critical raw materials (CRMs), vital to today’s high-tech society. ProSUM directly supports the European Innovation Partnership (EIP) on Raw Materials and its Strategic Implementation Plan calling for the creation of a European raw materials knowledge base. Data on primary and secondary raw materials are available in Europe, but scattered amongst a variety of institutions including government agencies, universities, NGOs and industry. By establishing a EU Information Network (EUIN), the project will coordinate efforts to collect secondary CRM data and collate maps of stocks and flows for materials and products of the “urban mine”. The scope is the particularly relevant sources for secondary CRMs: Electrical and electronic equipment, vehicles, batteries and mining tailings. The project will construct a comprehensive inventory identifying, quantifying and mapping CRM stocks and flows at national and regional levels across Europe. Via a user-friendly, open-access Urban Mine Knowledge Data Platform (EU-UMKDP), it will communicate the results online and combine them with primary raw materials data from the on-going Minerals4EU project. To maintain and expand the EU-UMKDP in the future, it will provide update protocols, standards and recommendations for additional statistics and improved reporting on CRM’s in waste flows required. ProSUM – “prosum” is Latin for “I am useful” – provides a factual basis for policy makers to design appropriate legislation, academia to define research priorities and to identify innovation opportunities in recovering CRMs for the recycling industry. The EUIN enables interdisciplinary collaboration, improves dissemination of knowledge and supports policy dialogues. A consortium of 17 partners, representing research institutes, geological surveys and industry, with excellence in all above domains will deliver this ambitious project.";3704327,57;3051577,57;H2020-WASTE-2014-one-stage;/CSA;WASTE OF ELECTRICAL AND ELECTRONICAL EQUIPMENT FORUM AISBL;BE;"UNITED NATIONS UNIVERSITY;THE WASTE AND RESOURCES ACTION PROGRAMME;RECHARGE;TECHNISCHE UNIVERSITAT BERLIN;BUREAU DE RECHERCHES GEOLOGIQUES ET MINIERES;EuroGeoSurveys - EGS;Geological Survey of Denmark and Greenland;CESKA GEOLOGICKA SLUZBA;SVERIGES GEOLOGISKA UNDERSOKNING;EC CONSULTING;EUROPEAN COMPLIANCE ORGANIZATIONS FOR BATTERIES;CENTRAAL BUREAU VOOR DE STATISTIEK;C-TECH INNOVATION LIMITED;EIDGENOSSISCHE MATERIALPRUFUNGS- UND FORSCHUNGSANSTALT;GEOLOSKI ZAVOD SLOVENIJE;TECHNISCHE UNIVERSITEIT DELFT;CHALMERS TEKNISKA HOEGSKOLA AB";"JP;UK;BE;DE;FR;DK;CZ;SE;NL;CH;SI";;1;0;0;1;0;0 207456;734560;ALICE;SIGNED;H2020-EU.1.3.3.;MSCA-RISE-2016;H2020;AcceLerate Innovation in urban wastewater management for Climate changE;2017-01-01;2020-12-31;;"The challenges facing society in urban wastewater management cannot be solved by any one sector alone. ALICE (AcceLerate Innovation in urban wastewater management for Climate changE) will accelerate innovation by bringing together and exchanging knowledge between the key players who can, together, address the future techno-economic, governance and societal challenges arising from climate change. It will boost international and interdisciplinary skills, as well as careers perspective of Experienced Researchers, Early Stage Researchers, and the workforce of industry, water utilities and public organizations. The results will 1) benefit water utilities, 2) support political and managerial decisions in wastewater, 3) benefit wastewater equipment manufacturers, identifying new market opportunities in the EU, 4) benefit EU citizens from the improved wastewater infrastructure, the environment and job creations. Higher precipitation and more frequent storms will require change in sewer water management. Moreover, higher risks of water scarcity and droughts require increased wastewater reuse, currently at 20% of its potential in the EU. These changes will lead to increased energy demand in a sector that is already a major contributor of carbon emissions. ALICE will promote effective solutions based on innovative technologies, green infrastructures, climate vulnerability assessments, governance and economic models, embracing stakeholders’ and citizens’ views to overcome barriers to the acceptance and uptake of new technologies. The excellence of the project lies in the joined-up thinking of different perspectives and disciplines. Academic and non-academic partners along the wastewater value-chain will exchange knowledge, develop training, research and innovation activities. ALICE will build lasting knowledge and cooperation networks and will provide the non-academic sector with practical solutions to respond in innovative ways to the challenges posed by climate change.";900000;900000;H2020-MSCA-RISE-2016;/MSCA-RISE;UNIVERSITY OF ULSTER;UK;"UNIVERSITA DEGLI STUDI DI MACERATA;DUBLIN CITY UNIVERSITY;MILITOS SYMVOULEUTIKI A.E.;ASET SPA;DIONERGY LIMITED;CENTRO DE INVESTIGACIONES ENERGETICAS, MEDIOAMBIENTALES Y TECNOLOGICAS-CIEMAT;THE QUEEN'S UNIVERSITY OF BELFAST;REDINN SRL;ASOCIACION BC3 BASQUE CENTRE FOR CLIMATE CHANGE - KLIMA ALDAKETA IKERGAI;REGION DE MURCIA;NORTHERN IRELAND WATER LIMITED;UNIVERSITY OF CYPRUS";"IT;IE;EL;ES;UK;CY";;1;0;0;1;0;0 205432;721802;SYNDEGEN;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2016;H2020;Synaptic dysfunction in Neurodegenerative Diseases;2017-01-01;2020-12-31;;Neurodegenerative diseases (NDDs) of aging are a growing burden on societies. Although studies on the degeneration of neurons have been a main focus of research, increasing evidence points to synapses as the site where Alzheimer’s disease (AD), Parkinson’s disease (PD) and Huntington’s disease (HD) begin. There is growing evidence that synapses are sites of early and aberrant protein misfolding, aggregation and spread in NDDs. A key problem in research on NDDs has been that the normal physiological roles at synapses of the aggregation-prone proteins (?- amyloid/amyloid precursor protein, tau, ?-synuclein and huntingtin), which are linked pathologically and genetically to these diseases, are not known. Using cutting-edge technologies and multidisciplinary approaches the SYNDEGEN consortium aims to bring together leading experts in cell biology, synapse biology and imaging, stem cell biology and NDDs in Europe to determine the molecular and cellular mechanisms whereby synapses become dysfunctional in AD, PD and HD for the purpose of developing novel therapies. The goal of the consortium is to train talented young scientists in interdisciplinary, innovative and collaborative research aimed at the development of novel molecular based treatment strategies for these major diseases of aging. A gap in the training of students in these important diseases is that disease expertise and novel methods to study synapses are localized in isolated groups in different locations in the EU. Similar questions are being asked about the mechanisms of synaptic dysfunction in AD, PD and HD, but no one university or company has sufficiently broad knowledge and technical expertise required to study and develop therapies for synaptic dysfunction in these disorders. This training programme will be implemented in 6 academic centres and 2 SMEs representing a comprehensive, highly interactive and multidisciplinary partnership.;3129428,16;3129428,16;H2020-MSCA-ITN-2016;/MSCA-ITN-ETN;LUNDS UNIVERSITET;SE;"DEUTSCHES ZENTRUM FUR NEURODEGENERATIVE ERKRANKUNGEN EV;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;Ecole Polytechnique Fédérale de Lausanne;UMECRINE AB;EXPLORA NOVA SARL;UNIVERSITAETSMEDIZIN GOETTINGEN - GEORG-AUGUST-UNIVERSITAET GOETTINGEN - STIFTUNG OEFFENTLICHEN RECHTS;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS";"DE;UK;CH;SE;FR";;1;0;0;1;0;0 205449;721906;TRACT;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2016;H2020;Training in Cancer Mechanisms and Therapeutics;2016-10-01;2020-09-30;;The European community requires early stage researchers (ESRs) trained in next-generation technologies for improved detection and treatment of oral and oesophageal cancers. The number of oral cancers diagnosed in the EU has increased by over 75% in the last 30 years, with long-term survival rates of only 50%. This is typically due to the late diagnosis of the disease and resistance to current therapies. Through the collaborative expertise of clinicians, biochemists, immunologists, and chemists TRACT will enable ESRs to discover novel insights into the molecular and cellular basis of these cancers and generate new diagnostic tools and therapeutics that improve patient response and survival. Each Institution brings unique but complementary expertise in cancer metabolism, metabolomics, high-resolution imaging, biomarker identification, computational modelling, medicinal chemistry, target validation, drug development and translational medicine. Industrial placements in five European countries will ensure ESRs receive specialised training in the development of next-generation technologies in such areas as whole genome sequencing, CRISPR technology, drug screening, exosome isolation and analysis, cancer imaging, metabolism and metabolite analysis in addition to the unique employment experience of working in the private sector. Courses in commercialisation, project management and presentation skills will ensure ESRs will have the ability to present their results to the entire cross-section of the European community, through public engagement. TRACT will deliver a cohort of internationally mobile cancer researchers with interdisciplinary skills who will have enhanced career prospects and be in a position to have an impact on the European and global research stage by providing new technologies that can drive entrepreneurship into the European economy and improved diagnostics and treatment options for cancer patients in Europe and beyond.;2877076,8;2877076,8;H2020-MSCA-ITN-2016;/MSCA-ITN-ETN;THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN;IE;"OROBOROS INSTRUMENTS GmbH;UNIVERSITA' DEGLI STUDI DI SIENA;UNIVERSITAT DE VALENCIA;THE QUEEN'S UNIVERSITY OF BELFAST";"AT;IT;ES;UK";;1;0;0;1;0;0 201447;706680;EquiPE;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Balancing social equity and biodiversity outcomes in protected area management.;2017-01-10;2019-01-09;;"We are in the midst of the earth’s sixth mass extinction and the search for effective conservation solutions has never been more pressing. In recent years the model for nature conservation has changed, deeply embedding safe-guarding livelihoods and maximising equity within the missions of most conservation organisations. Re-focusing conservation in this way is based on the assumption that more socially equitable conservation will be both more acceptable to stakeholders, thereby reducing the likelihood of conflict with conservationists, and ultimately more effective in protecting biodiversity. That is the key hypothesis which will be tested in this fellowship. To achieve this I will address three key research objectives: 1) To devise a metric of equity in protected area governance and assess under which conditions protected area governance can be considered most equitable; 2) To explore how variation in equity in protected area governance influences acceptability of the protected area; and 3) To uncover how variation in equity in protected area governance relates with good biodiversity outcomes. I will meet these objectives through: 1) the development of an index of equity based on up-to-date theory and using protected area management plans; 2) a review of conflicts around protected areas and how these relate to equity in the governance of protected areas; and 3) large-scale spatial analyses of protected area effectiveness and forest change in relation to equity. While working in leading European research groups and gaining excellent training in interdisciplinary theory and up-to-date analytical methods, I will: (1) improve knowledge of outcomes of protected area management using recently available data sets; (2) provide conservationists with guidance for the design of protected area management plans; and (3) help the implementation of European Directives by providing a framework to design and analyse effectiveness of conservation measures.";183454,8;183454,8;H2020-MSCA-IF-2015;/MSCA-IF-EF-RI;THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN;UK;;;;1;0;0;1;0;0 198452;648039;DUB-DECODE;SIGNED;H2020-EU.1.1.;ERC-CoG-2014;H2020;Systematic Decoding of Deubiquitylase-Regulated Signaling Networks;2015-10-01;2020-09-30;;Cellular processes are largely governed by sophisticated protein posttranslational modification (PTM)-dependent signaling networks, and a systematic understanding of regulatory PTM-based networks is a key goal in modern biology. Ubiquitin is a small, evolutionarily conserved signaling protein that acts as a PTM after being covalently conjugated to other proteins. Reversible ubiquitylation forms the most versatile and largest eukaryote-exclusive signaling system, and regulates the stability and function of almost all proteins in cells. Deubiquitylases (DUBs) are ubiquitin-specific proteases that remove substrate-conjugated ubiquitin, and thereby regulate virtually all ubiquitylation-dependent signaling. Because of their central role in ubiquitin signaling, DUBs have essential functions in mammalian physiology and development, and the dysregulated expression and mutation of DUBs is frequently associated with human diseases. Despite their vital functions, very little is known about the proteins and ubiquitylation sites that are regulated by DUBs and this knowledge gap is hampering our understanding of the molecular mechanisms by which DUBs control diverse biological processes. Recently, we developed a mass spectrometry-based proteomics approach that allowed unbiased and site-specific quantification of ubiquitylation on a systems-wide scale. Here we propose to comprehensively investigate DUB-regulated ubiquitin signaling in human cells. We will integrate interdisciplinary approaches to develop next-generation cell models and innovative proteomic technologies to systematically decode DUB function in human cells. This will enable a novel and detailed understanding of DUB-regulated signaling networks, and open up new avenues for further research into the mechanisms and biological functions of ubiquitylation and of ubiquitin-like modifiers.;1972570;1972570;ERC-2014-CoG;/ERC-COG;KOBENHAVNS UNIVERSITET;DK;;;;1;0;0;1;0;0 220731;810207;ArpComplexity;SIGNED;H2020-EU.1.1.;ERC-2018-SyG;H2020;Defining the role of Arp2/3 complex diversity at multiple scales of biology;2019-07-01;2025-06-30;;"The actin cytoskeleton of the cell is critical for the complex, integrated processes associated with development, operation and sustainability of the human body. The Arp2/3 complex consisting of seven protein subunits is essential to stimulate dynamic branched actin networks needed for multiple cellular processes. The Arp2/3 complex has always been considered as a single entity, but in humans and other mammals, three of the Arp2/3 complex subunits are encoded by two isoforms, thus allowing the formation of eight distinct Arp2/3 complexes. The Way lab has shown that Arp2/3 subunit composition dramatically affects the formation and stability of branched actin networks. The Way and Gomes labs have shown how specific Arp2/3 isoforms are essential for muscle development. Our synergistic, high-risk, high-gain goal is to define the role of Arp2/3 complex diversity at three hierarchies of biology: 1. Molecular basis of Arp2/3 diversification With purified isoform-specific complexes we will perform cryo-electron microscopy and single molecule fluorescence microscopy to reveal the structural variations and influence of Arp2/3 diversity on actin networks in vitro. 2. Cellular function of different Arp2/3 complexes With cells expressing specific Arp2/3 isoforms, we will use quantitative live cell imaging and cryoelectron tomography to reveal the dependence of cellular actin networks on Arp2/3 diversity and its functional consequences. 3. Developmental and physiological role of individual Arp2/3 complexes. With genetically modified cultured myofibers and transgenic mice, we will use an array of imaging approaches to reveal the contribution of different Arp2/3 family members to muscle development, structure and physiology. Our interdisciplinary plan builds on the strengths of our three labs, takes advantage of unique reagents and powerful model systems, and will allow us to determine how Arp2/3 diversity contributes to biological complexity at multiple scales.";10715153;10715153;ERC-2018-SyG;/ERC-SyG;THE FRANCIS CRICK INSTITUTE LIMITED;UK;"BIRKBECK COLLEGE - UNIVERSITY OF LONDON;INSTITUTO DE MEDICINA MOLECULAR JOAO LOBO ANTUNES";"UK;PT";;1;0;0;1;0;0 220730;810367;EMC2;SIGNED;H2020-EU.1.1.;ERC-2018-SyG;H2020;Extreme-scale Mathematically-based Computational Chemistry;2019-09-01;2025-08-31;;"Molecular simulation has become an instrumental tool in chemistry, condensed matter physics, molecular biology, materials science, and nanosciences. It will allow to propose de novo design of e.g. new drugs or materials provided that the efficiency of underlying software is accelerated by several orders of magnitude. The ambition of the EMC2 project is to achieve scientific breakthroughs in this field by gathering the expertise of a multidisciplinary community at the interfaces of four disciplines: mathematics, chemistry, physics, and computer science. It is motivated by the twofold observation that, i) building upon our collaborative work, we have recently been able to gain efficiency factors of up to 3 orders of magnitude for polarizable molecular dynamics in solution of multi-million atom systems, but this is not enough since ii) even larger or more complex systems of major practical interest (such as solvated biosystems or molecules with strongly-correlated electrons) are currently mostly intractable in reasonable clock time. The only way to further improve the efficiency of the solvers, while preserving accuracy, is to develop physically and chemically sound models, mathematically certified and numerically efficient algorithms, and implement them in a robust and scalable way on various architectures (from standard academic or industrial clusters to emerging heterogeneous and exascale architectures). EMC2 has no equivalent in the world: there is nowhere such a critical number of interdisciplinary researchers already collaborating with the required track records to address this challenge. Under the leadership of the 4 PIs, supported by highly recognized teams from three major institutions in the Paris area, EMC2 will develop disruptive methodological approaches and publicly available simulation tools, and apply them to challenging molecular systems. The project will strongly strengthen the local teams and their synergy enabling decisive progress in the field.";9991997;9991997;ERC-2018-SyG;/ERC-SyG;SORBONNE UNIVERSITE;FR;"INSTITUT NATIONAL DE RECHERCHE ENINFORMATIQUE ET AUTOMATIQUE;ECOLE NATIONALE DES PONTS ET CHAUSSEES";FR;;1;0;0;1;0;0 220577;802441;UNMAKING;SIGNED;H2020-EU.1.1.;ERC-2018-STG;H2020;Societal transformation to sustainability through the unmaking of capitalism? A comparative study of radical grassroots innovations in Europe;2019-02-01;2024-01-31;;"Modern capitalist societies engage destructively with the natural environment. Societal transformation to sustainability is urged, but it implies a degree of disruption of modern, capitalist ways of being and doing. Radical grassroots innovations – those that posit a profound cultural, economic, and political transformation of dominant institutions and practices - hold the potential to lead such transformation, but may be constrained by their marginal, local, small-scale character. This programme aims to understand to what extent, under what conditions, and through what processes radical grassroots innovations unmake modern, capitalist institutions and practices. This research will compare Italian and German radical grassroots innovations in agriculture to: (1) identify and categorize mechanisms of unmaking that are involved in radical grassroots innovations; (2) explain whether and how unmaking creates space for alternatives from the individual to the social-ecological level; (3) understand how mechanisms of unmaking at different levels interplay; (4) explain why unmaking may result in different outcomes in different context; (5) develop a theory of unmaking in societal transformation to sustainability.This research is ground breaking as it (1) approaches societal transformation from the perspective of unmaking of dominant institutions, rather than of the introduction of innovations, (2) mobilizes theories that have so far not been considered, and innovatively integrates theories and levels of analysis, (3) originally employs mixed methods that capture trajectories of change, and enable to generalize causal mechanisms in complex social-ecological systems. This programme will push the boundaries of our understanding of transformation to sustainability. It will generate scientific knowledge that will be relevant across the social sciences, offer a theoretical lens –unmaking-, and test a process-tracing methodological approach to stimulate interdisciplinary research.";1498200;1498200;ERC-2018-STG;/ERC-STG;UNIVERSITEIT UTRECHT;NL;;;;1;0;0;1;0;0 195588;658330;DEEPER;TERMINATED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Deep Earth Elastic Properties and Effective Rheology;2015-07-30;2017-07-29;;"The interface between the Earth’s rocky mantle and molten outer core, located 2900 km below the surface, is marked by a patchwork of enigmatic structures. These structures, revealed by anomalous reductions in the speed of traveling seismic waves, are characterized by high density, partial melting, and low topographic heights (10-40 km above the core-mantle boundary). Due to the low seismic wave speeds, they are called UltraLow Velocity Zones (ULVZs). Since their ?rst discovery in the 90s, our understanding of the ULVZs has been based on seismic observations. The in?uence of microscale distribution of melt and minerals on the seismic signature and the internal structure of the ULVZs remain a challenging question in geophysics. To address this question, this project will use a cross-scale approach to quantify the in?uence of partial melting and solid composition on the elastic properties and rheology of the UL-VZs based on a microstructural model. Using the microscale constraints on the physical properties, the km-scale internal structure of the ULVZs will be simulated using a ?nite elements model. The interdisciplinary approach of this project relies on using state-of-the-art high performance computational ?uid mechanics models to answer fundamental questions in Earth Sciences. The uniqueness of this approach arises from the special consideration of microstructures, a crucial, but dif?cult to quantify aspect in Earth sciences. The multidisciplinary aspect of this work will train the researcher in new modeling skills. Upon his return to India, where research in deep Earth is still in its infancy, the researcher will be able to establish his own research agenda leading the country’s effort in that area. Continued inter-national collaboration between the host institution and the researcher’s future group will be of enduring value to the EU.";183454,8;183454,8;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;ROYAL HOLLOWAY AND BEDFORD NEW COLLEGE;UK;;;;1;0;0;1;0;0 197130;665779;COFUND-FP-CERN-2014;SIGNED;H2020-EU.1.3.4.;MSCA-COFUND-2014-FP;H2020;COFUNDing of the CERN Fellowship Programme 2014;2015-10-01;2020-09-30;;"Abstract For many years, CERN has operated a trans-national Fellowship programme, offering scientists and engineers challenging opportunities in particle physics research, and in related fields of physics and technology. CERN secured COFUND grants in 2008, 2010, 2011 and 2012. They offer CERN a timely opportunity to enhance the mobility element of this programme without nationality limitations. The 2014 Call comes at the end of the Large Hadron Collider’s first long shutdown which once more makes CERN one of the most exciting places to work for the global physics and technology community. Applicants will propose their own research projects. Selection will be based on the scientific potential of the proposal, and on the demonstrated excellence of the candidate. Working on frontier research and technology projects and profiting from the unique facilities available at CERN, the co-funded Fellows will deepen their knowledge in their own field and acquire international visibility and reputation. They will broaden their skills using the numerous training opportunities and through their exposure to an interdisciplinary and multi-national environment. Inter-sectoral skills will be fostered through CERN’s industrial collaborations and technology transfer projects. Attractive and competitive employment conditions are maintained by guaranteeing three-year appointments rather than the standard two-year terms of CERN Fellows. At least two of these three years will be spent at CERN. We consider this provision to be justified by the size of the Laboratory, the diversity of the research and training opportunities, and by the uniqueness of CERN’s facilities. However, mobility will be enhanced through the opportunity to spend up to one third of the Fellowship in external institutions, including industrial laboratories, on paid leave from CERN under the conditions of the full employment contract.";12744000;6372000;H2020-MSCA-COFUND-2014;/MSCA-COFUND-FP;EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH;CH;;;;1;0;0;1;0;0 220271;823961;LoGov;SIGNED;H2020-EU.1.3.3.;MSCA-RISE-2018;H2020;Local Government and the Changing Urban-Rural Interplay;2019-02-01;2023-01-31;;"LoGov aims to form an international and intersectoral training and research network in order to provide best-fit practices for local governments to address the changing urban-rural interplay and manage its impacts. As a global Consortium composed of eight European and nine non-European partners, we seek to (1) to identify, evaluate, compare and share practices in five major local government areas (local responsibilities, local finances, local government structure, intergovernmental relations and people’s participation); (2) to encourage the effective application of the best-fit practices by local governments; (3) to strengthen international and intersectoral collaborative research; (4) to enhance the career perspectives of the staff involved by increasing their mobility both within the academic and the non-academic sectors and between these sectors. LoGov’s methodological approach relies on a comprehensive comparative analysis that draws on findings from 15 countries or wider regions on six continents, the extensive involvement of local policy-makers through local government associations and a multi- and interdisciplinary approach that is facilitated by the Consortium’s expertise in four disciplines (public law, political science, public administration and economics). The training strategy of LoGov is based on both secondment-related and network-wide activities. The strategy combines well-established events with newly developed transferable and research skills training, including open science, communication and research transfer training. To achieve the maximum impact, LoGov’s dissemination strategy targets both the wider scientific community and local policy-makers. It does so when sharing the key training result of widening career perspectives and the main research result of providing best-fit practices for local governments. These contribute to making them more resilient in light of changing urban-rural relations, a primary societal challenge of our times.";1610000;1311000;H2020-MSCA-RISE-2018;/MSCA-RISE;ACCADEMIA EUROPEA DI BOLZANO;IT;"UNIWERSYTET WARSZAWSKI;LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN;COUNCIL OF EUROPE - CONSEIL DE L'EUROPE;XIMPULSE GMBH;KDZ - ZENTRUM FUR VERWALTUNGSFORSCHUNG;NALAS (RESEAU DES ASSOCIATIONS NATIONALES DE POUVOIRS LOCAUX DE L'EUROPE DU SUD-EST);UNIVERSIDAD AUTONOMA DE MADRID;ZDRUZENIE NA OPSTINI ZAEDNICA NA EDINICITE NA LOKALNATA SAMOUPRAVA NAREPUBLIKA MAKEDONIJA-ZELS SKOPJE;UNIVERSITE DE FRIBOURG";"PL;DE;FR;CH;AT;ES;MK";;1;0;0;1;0;0 220296;802631;HEALFAM;SIGNED;H2020-EU.1.1.;ERC-2018-STG;H2020;The effects of unemployment on health of family members;2019-03-01;2024-02-29;;"Previous research has investigated the relationship between unemployment and health from a perspective of an isolated individual. HEALFAM takes a novel approach and examines how transition to unemployment triggers diffusion of ill mental and physical health within families. It investigates how becoming unemployed affects health outcomes of partners, children and elderly parents of the unemployed and whether the magnitudes of these influences differ across families and societies. Thus, instead of viewing the unemployed as functioning in isolation, HEALFAM assesses the consequences of unemployment for family members taking a multi-actor perspective and international comparative approach. Guided by the life course theoretical framework, which views health and well-being as a process rather than a state and calls for considering interrelatedness of individuals, HEALFAM employs longitudinal data that provide information about multiple members of families. In order to analyse these datasets, HEALFAM uses longitudinal dyadic data analysis techniques as well as multilevel models for longitudinal data. HEALFAM aims to open a new frontline of research on health and wellbeing from a life course perspective. It benefits from my knowledge on three interrelated social phenomena: (1) the role of labour market career and experiences of unemployment (2) family structure and intra-family resources (3) social antecedents of health and wellbeing among family members. It draws on high quality register and panel survey data as well as the expertise at the interdisciplinary research centres that I am connected to at Ume? University. Through international collaborations, it brings together experts in multiple disciplines carrying out research taking a life course perspective.";1477556,25;1477556,25;ERC-2018-STG;/ERC-STG;UMEA UNIVERSITET;SE;;;;1;0;0;1;0;0 214173;796910;PICS;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Prediction in Complex Systems;2018-09-10;2020-09-09;;"Prediction has traditionally been viewed as a hallmark of successful science by scientists and philosophers alike. In recent years however, interest in prediction has declined, as philosophers have shifted their focus to explicating scientific explanation, while scientists have settled on a standard notion of the term. Unfortunately, this displacement is premature, as it obscures conceptual issues that are becoming increasingly important in scientific practice. Perhaps the most important of these issues is why some sciences (e.g. economics, ecology and climate science) face disproportionate difficulties in making predictions that are sufficiently precise and accurate. This issue has important implications within and outside academia, as it affects our expectations and evaluations of scientific practice. The overall aim of this project is to provide a new philosophical framework for understanding prediction, which takes into account the difficulties faced by these sciences. The project’s objectives will be to provide answers for three distinct but related questions: (i) what are the causes of the problem of prediction? (ii) what are some possible solutions to the problem of prediction? (iii) what are the implications for our conception of ‘prediction’? This interdisciplinary Global Fellowship will be pursued at the University of Helsinki and the Australian National University. Training objectives include the creation of a novel conceptual framework, its application to current scientific practice (in economics and ecology) and training in dissemination strategies. The hosting institutions will also provide training in effective publication and collaboration strategies as well as mentoring and supervision. The action will provide networking opportunities for the researcher and host institutions. Special attention will be paid to the extra-academic dissemination of the project’s results.";172852,8;172852,8;H2020-MSCA-IF-2017;/MSCA-IF-GF;HELSINGIN YLIOPISTO;FI;;;;1;0;0;1;0;0 214199;798532;SPECTROCHEM;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;First-Principles Spectroscopies in Realistic Electrochemical Environments;2018-07-01;2020-06-30;;"Electrocatalysis will play a central role in achieving the goal of a clean-energy cycle that goes from energy harvesting to storage and delivery. Challenges abound, but many efforts are taking place in the experimental and computational communities. We believe that in order to unravel the elementary steps of electrocatalytic reactions a unique and powerful drive will come from the development of computational techniques able to predict in-operando spectroscopic data. In fact, experimental spectroscopic techniques can offer exquisitely precise data, that nevertheless requires accurate, predictive computational models to be interpreted and translated into an atomistic mechanism. This proposal will be dedicated to the development of first-principles modelling of realistic electrochemical environments, and to the calculation of in-operando computational spectra. In particular, during this fellowship I will: (i) apply novel strategies to account for the presence of the solvent, the electrolyte and the electrode potential in quantum mechanical simulations; (ii) implement computational approaches that will enable the accurate prediction and interpretation of infrared- and X-ray-based spectroscopies; (iii) investigate the carbon dioxide reduction on model copper catalysts, advancing the current understanding of this relevant electrochemical process. This Marie Sk³odowska-Curie fellowship will allow me to work in a group that is at the forefront of computational materials science and materials design, and in tight partnership with world class experimental efforts. This proposal entails numerous measures that will allow me to enlarge my collaboration network and develop new interdisciplinary skills, boosting in the process my career as independent researcher.";175419,6;175419,6;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE;CH;;;;1;0;0;1;0;0 212998;778072;ENGIMA;SIGNED;H2020-EU.1.3.3.;MSCA-RISE-2017;H2020;Engineering of Nanostructures with Giant Magneto-Piezoelectric and Multicaloric Functionalities;2017-12-01;2021-11-30;;Nowadays smart materials play a crucial role in the next-generation of intelligent devices and sensors, smart homes, autonomous devices, and robotics. Nanostructuring materials open up new horizons bringing in their multifunctionality and reduce the energy consumption. This reveals new scientific avenues and paves ways for breakthroughs in technology. Realization of structured materials with the strong coupling of electric and magnetic order and large multicaloric properties is a milestone for modern electronics and the gate for fascinating applications. In this context, we develop the partnership within the RISE consortium ENGIMA, involving the academic partners from two EU Member States, France and Slovenia Third Countries Universities in Morocco and Russia the non-academic SME from Associated Country, Ukraine. The network combines the complementary interdisciplinary and intersectoral expertise with established collaboration between partners and clear potential for skills transfer and exchange of knowledge, extended from fundamental to applied physics and from material chemistry to industrial nanotechnologies. Consortium defined a research objective of exploring the nanostructures in a form of tethered magnetic 1-D/piezoelectric nanostructures and magnetic/piezoelectric superlattices to obtain new ferroic materials with giant magnetoelectric and multicaloric functionalities that have potential applications as magnetoelectric sensors and, telecommunication devices. This task will be achieved by joining the efforts through the staff exchange, sharing knowledge, innovation and by multidisciplinary training of the team of collaborating young researchers able to conduct the research and exploit its application to this new area.;936000;837000;H2020-MSCA-RISE-2017;/MSCA-RISE;UNIVERSITE DE PICARDIE JULES VERNE;FR;"INSTITUT JOZEF STEFAN;NANOTECHCENTER LLC";"SI;UA";;1;0;0;1;0;0 199556;677423;SHAPE;SIGNED;H2020-EU.1.1.;ERC-StG-2015;H2020;Structure-dependent microkinetic modelling of heterogeneous catalytic processes;2016-05-01;2021-04-30;;"Despite the fact that the catalyst structure has been an important factor in catalysis science since the discovery of structure sensitive reactions in single crystal studies, its effect on reactivity is neglected in state-of-the-art microkinetic modelling. In reality, the catalyst is dynamic by changing its structure, shape and size in response to the different conditions in the reactor. Thus, the inclusion of such effects within the framework of microkinetic modelling, albeit extremely complex, is of outmost importance in the quest of engineering the chemical transformation at the molecular level. This proposal aims to approach this grand challenge by developing a hierarchical multiscale methodology for the structure-dependent microkinetic modelling of catalytic processes in applied catalysis. In particular this challenging objective will be achieved by acting on two main fronts: i. development of a hierarchical multiscale methodology for the prediction of the structural changes of the catalyst material as a function of the operating conditions in the reactor and the analysis of the structure-activity relations through the development of structure-dependent microkinetic models; ii. show the applicability of the methodology by the assessment of the structure-activity relation in the context of relevant processes in energy applications such as the short-contact-time CH4 reforming with H2O and CO2 on supported-metal catalysts. The inherent complexity of the problem will be tackled by hierarchically combining novel methods at different levels of accuracy in a dual feed-back loop between theory and experiments. This will require interdisciplinary efforts in bridging among surface science, physical-chemistry and chemical engineering. The fundamental nature and impact of the methodology will be unprecedented and will pave the way toward the detailed analysis and design of the structure-activity relation by tuning shape and size to tailoring activity and selectivity.";1496250;1496250;ERC-2015-STG;/ERC-STG;POLITECNICO DI MILANO;IT;;;;1;0;0;1;0;0 211915;766894;PEGASUS;SIGNED;H2020-EU.1.2.1.;FETOPEN-01-2016-2017;H2020;Plasma Enabled and Graphene Allowed Synthesis of Unique nano Structures;2017-11-01;2021-10-31;;'PEGASUS ultimate goal is to create a highly efficient, catalyst/harmful-free novel plasma method along with a proof-of-concept PEGASUS device for a large-scale N-graphene direct synthesis, as well as N-graphene/MnO2/Fe2O3/SnO2 composites and unique vertical N-graphene arrays grown on metal substrates, via breakthrough research on plasma-enabled singular assembly pathways. By doing so, a disruptive and highly competitive alternative to conventional lengthy/multistep routes will emerge, based on the mastering of plasma exclusive mechanisms to control the amount and localization of energy and matter at atomic scales, spurring a new European manufacturing/processing platform. The envisioned path will prompt and build on ground-breaking developments in the underlying physics, with the resulting processes embodying invaluable economic/social impact potential. PEGASUS framework is uniquely positioned to succeed and raise the Europe competitiveness in the strategic nano synthesis domain via the promotion of plasma methods as a Key Enabling Technology for highly controllable and 'green' assembly of atom-thick hybrid nanostructures and by replacing long existing materials with new cost-effective, higher performance ones. The synergy between plasma physics and mechanical, electrochemical and hi-tech engineering expertise will be the driving force boosting the innovative approach pursued by this project, spanning from fundamental knowledge to appliance prospects. Internationally recognized scientists will contribute to this interdisciplinary project, triggering the commercialization of novel materials and delivering proof-of-concept PEGASUS and supercapacitor devices. With a science-devoted team lead by a female coordinator, PEGASUS contribution ambitions go beyond the scientific scope, helping to bridge economical/social gaps in tune with the EU ambitions.';3999633,75;3764276,25;H2020-FETOPEN-1-2016-2017;/RIA;ASSOCIACAO DO INSTITUTO SUPERIOR TECNICO PARA A INVESTIGACAO E DESENVOLVIMENTO;PT;"CHARGE2C-NEWCAP LDA;INSTITUT JOZEF STEFAN;SOFIISKI UNIVERSITET SVETI KLIMENT OHRIDSKI;CHRISTIAN-ALBRECHTS-UNIVERSITAET ZU KIEL;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS";"PT;SI;BG;DE;FR";;1;0;0;1;0;0 209658;752489;SODIUMMRI-4-EU;CLOSED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Unlocking the potential of ultrahigh field 23Na magnetic resonance to quantify tissue sodium content for probing viability of the heart: where physics, biology and medicine meet;2018-01-01;2019-12-31;;Cardiovascular diseases (CVD) are the leading cause of death with 60% of CVDs associated with coronary artery diseases (CAD). CAD is the major cause of myocardial infarction (MI), commonly known as heart attack, which can be life threatening and places a huge socio-economic burden on the EU. The most widely used therapy for CAD is revascularization, and myocardial viability is a determining factor and predictor for patient outcomes. Magnetic resonance imaging (MRI) has become a mainstay of clinical diagnosis, but so far has seen limited use in the study of the heart. Here I aim to unlock the potential of myocardial viability imaging with physiometabolic MRI to provide a new instrument for the diagnosis and assessment of therapy success of CAD. Therefore I propose a quantitative approach based on MRI of sodium (23Na) that will allow me to observe new features of the working heart, at a level of resolution that will be highly valuable in understanding, finely diagnosing, and designing treatments for CVD. To meet this goal I pursue the development of cutting edge sodium MRI technology. Its capacity for quantitative assessment of sodium tissue content will be validated in model systems and in healthy subjects. The clinical applicability of 23Na MRI for viability imaging will be examined in revascularized MI patients. For this purpose I will leverage the sensitivity gain inherent to ultrahigh field MRI (B0?7.0 T), capitalize on my outstanding expertise in the field of physiometabolic MRI and build on my interdisciplinary skills formed around MRI physics. In this project, this expertise will be taken to the next level to elucidate the progression of sodium concentration in ischemic myocardial tissue. This research will eliminate the main barriers to the study of tissue viability and will open entirely new possibilities for non-invasive, in vivo phenotyping as a tool for individualised medicine tailored to offset a major socio-economic burden on the EU induced by CVD.;171460,8;171460,8;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;MAX-DELBRUCK-CENTRUM FUR MOLEKULAREMEDIZIN;DE;;;;1;0;0;1;0;0 212271;747948;SUGARSmart;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;SUGARSmart: Smart design of recombinant antibody fragments specific for carbohydrate molecules;2018-07-10;2020-07-09;;"The development of new approaches to explore the diverse role of glycans in normal and physio- pathological conditions of the cell is a major challenge. Our previous research recognized roles of anti-glycan recognition molecules (lectins and antibodies) in the diagnosis of diseases like cancer, immunity, and hyperacute rejection upon bioprosthetic transplantation etc. However, because of the structural complexity, well-established approaches for developing glycan-based therapeutics are limited. To address this issues, SUGARSmart aims to develop a workflow for rational design of single-chain fragment variable (scFv) antibodies to enhance glycan recognition capabilities, both specificity- and affinity-wise (improving detection limits of assays). Three major aims will be pursued: First, we will apply molecular modeling to predict mutations which lead to enhance affinity and specificity of anti-?Gal scFv. A range of mutational strategies will be tested in order to learn which scFv domains, which particular locations (functionally important sites), and which mutations (aromatic or polar) are best suited to improve affinity and specificity. Second, computationally predicted mutants will be obtained by mutagenesis or chain shuffling. Validity of the predictions will be tested by affinity-measurement (ITC/SPR), array techniques and ELISA. At the end, validation of computational models of scFv-glycan interactions with experimental techniques will enable us to propose a workflow to engineer other anti-glycan scFv antibodies. Overall, this project proposes an interdisciplinary approach to enhance our ability to quantify and engineer glycan recognition molecules having potential application in the smart and tailored development of future diagnostic reagents and therapeutics. To the best of our knowledge this will be the first attempt to provide a complete and coherent framework for anti-glycan antibody engineering, combining a wide computational pipeline and experiments.";175866;175866;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;NATIONAL UNIVERSITY OF IRELAND GALWAY;IE;;;;1;0;0;1;0;0 209316;749944;MUTAnTS;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;A microfluidic high throughput approach to helicase biophysics;2018-02-01;2020-01-31;;We propose a novel high-throughput method to study the chemo-mechanical coupling in molecular motors using helicases, enzymes that couple ATP hydrolysis to unwinding of the double helix, as a model system. The method combines a cell-free expression system, droplet microfluidics and fluorescent assays with next generation sequencing to test large (up to millions of elements) libraries of helicase mutants for both unwinding and ATPase activity. The aim is to identify all sequence positions that, if mutated, lead to uncoupling, i.e. abolish unwinding while preserving ATPase activity. Once these positions are identified, their distribution on the enzyme sequence and structure will be analysed to obtain insight into the coupling mechanism. Notably the methodology could be applied to systems where the classical, structure-based analysis of the chemo-mechanical coupling is not possible. We will demonstrate our method on the RecQ helicase from e. coli using existing information on this system as a means of validation. Any further insight will be a demonstration of the power of our approach. When fully developed, our method will serve as a discovery tool for the interdisciplinary community working on helicases that includes medical, biological and physical sciences. It may be applied to aspects of helicase biophysics beyond the chemo-mechanical coupling, to other enzyme families and to screen for helicase inhibitors with higher throughput and lower cost when compared to robotic mictotitre-plate techniques. The proposed work will be carried out at the Griffiths Lab (ESPCI Paris) with a secondment at the Crick Institute (London). This project integrates the training in biophysics of the Experienced Researcher with the expertise of the Host Institution on high-throughput methods and the experience of the Secondment Institution on helicases. The Experienced Researcher will be trained in next generation sequencing and fluorescence-based approaches to molecular motors.;173076;173076;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;ECOLE SUPERIEURE DE PHYSIQUE ET DECHIMIE INDUSTRIELLES DE LA VILLE DEPARIS;FR;;;;1;0;0;1;0;0 209256;747658;CKI;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Counterfactual Knowledge from the Imagination;2018-09-01;2020-08-31;;"Thoughts about counterfactual situations are a central feature of human cognition, key to planning in any domain of activity: What would happen if I missed a mortgage payment? What if Britain were to leave the EU? It seems that knowledge about counterfactual situations is possible under some circumstances. The project’s general aim is to improve our understanding of those circumstances, and what role the imagination plays in specifying them. The specific objectives are to investigate: (1) the connection between the epistemology of counterfactual conditionals and the epistemology of claims involving modal terms like “possible”, “necessary”, and “can”, (2) the role of the imagination in the epistemology of thought experiments in science, and (3) the cognitive architecture underlying counterfactual thinking. Over the course of investigating (1)-(3), I develop and defend the view that certain constrained imaginative exercises can provide knowledge about counterfactual situations. I will carry out this research within the interdisciplinary setting of the Institute for Logic, Language and Computation and the Department of Philosophy at the University of Amsterdam. My supervisor Francesco Berto is investigating questions highly relevant to my project’s, especially in his current work that develops a logic of conceivability. I will also make two visits to Oxford Philosophy to discuss my project research with Timothy Williamson, who has made some of the key contributions to the epistemology of counterfactual thinking and the imagination to date. The project will give me the opportunity to establish myself as an important scholar in analytic philosophy. By the project’s end, I will have submitted four articles to internationally leading journals in the field. The project will also enhance cooperation between UvA (ILLC/Philosophy) and Oxford (Philosophy).";165599,3;165598,8;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;UK;UNIVERSITEIT VAN AMSTERDAM;NL;;1;0;0;1;0;0 206996;721297;GlycoImaging;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2016;H2020;Imaging and detection of tumor-associated glycan structures on tumor cells;2017-04-01;2021-03-31;;"The overall objective of Glyco Imaging is to develop novel assays for detection of glycans as biomarkers associated with aggressive and metastatic cancer forms. The assays will be developed for biomarker detection in blood, urine, cells and tissue. Molecularly Imprinted Polymers (MIPs), or plastic antibodies, have been developed for targeting the human glycan sialic acid (SA), or Neu5Ac. The efficiency of the Neu5Ac specific SAMIPs targeted to the biomarker SA in different solvents (methanol, water, phosphate buffer) will be exploited. The non-human Neu5Gc, which is incorporated into human glycoconjugates through dietary sources such as red meat, and shown to be involved in malignant cell transformation in humans, will also be investigated by using highly specific Neu5Gc-SAMIPs. The imaging and detection techniques used will be based on fluorescence, 3D-viewing of cancer cells by digital holographic microscopy and magnetic separation columns. The results in this research consortium will lead to major technological advances having impact on 1) health care, since it will develop more accurate and reliable diagnostics of aggressive and metastatic cancers, 2) drug discovery allowing a faster and cheaper biomarker targeting and detection; and 3) biochemistry research laboratories in resulting in improved understanding of glycan expression in cancer, with emphasis on aggressive metastatic cancer. The training of researchers will be performed by a consortium consisting of 6 partners with biomedical, imaging and particle synthesis skills (4 groups, one institution, one technology company). This forms the basis for a very competent interdisciplinary training program with high quality in both education and research. 8 early stage researchers (ESRs) working on specific tasks within 5 work packages will follow a rich training program providing a well-balanced spectrum of scientific, business and entrepreneurial skills.";2138720,04;2138720,04;H2020-MSCA-ITN-2016;/MSCA-ITN-ETN;MALMO UNIVERSITET;SE;"KOBENHAVNS UNIVERSITET;UMEA UNIVERSITET;PHASE HOLOGRAPHIC IMAGING PHI AB;BUNDESANSTALT FUER MATERIALFORSCHUNG UND -PRUEFUNG;TURUN YLIOPISTO";"DK;SE;DE;FI";;1;0;0;1;0;0 201589;708200;ADVANTA;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Toward a new generation of miniature multifrequency antennas using multiresonance platform based on subwavelength structures inspired by advanced metamaterials;2017-08-01;2019-10-28;;"Mobile multiservice communication devices are constantly used in people’s daily life with ever increasing demand for cost effective, multiband and smaller antennas. The planned research is dedicated to development of a theoretical basis and a design approach for a new generation of miniature multifrequency antennas enabling up to ten various services at 0.8GHz to 10GHz simultaneously. This multiresonance antenna platform will be realized with the aid of subwavelength multiresonator structures where the individual resonators represent unit cells of the specially designed metamaterials (MTMs). The project has a pronounced interdisciplinary nature by merging antenna theory, material science, advanced modelling and design for manufacturability as well as measurements. Two new applied theoretical frameworks will be developed for (i) scaling subwavelength resonances and (ii) connection of characteristics of radiation and MTM cells. They will be utilized for design of miniature multifrequency antenna systems with up to tenfold difference between operation frequencies. Proof of concept will be done for monopole/dipole type antennas and then transferred to patch antennas. Thus, a route to a new generation of multifrequency antenna systems will be found, creating a practical development framework for the demanded innovation in multifunctional communication systems. The mobility will give the researcher an opportunity to acquire new knowledge in applied antenna design and assessment. With his recognized theoretical background and proficiency in novel materials applied for antennas, the career development towards a leading position inside or outside academia will be fulfilled. An extensive mutual transfer of knowledge will be beneficial for both the researcher and the host institute. The project will inspire novel utility mobile and wearable devices, which will improve the overall quality of life and enhance competitiveness of the EU industry.";172800;172800;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;KATHOLIEKE UNIVERSITEIT LEUVEN;BE;;;;1;0;0;1;0;0 201254;704681;FRoST;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;The Foreshock and its Role in Solar-Terrestrial relations;2017-03-15;2019-03-14;;"There is a critical need for accurate space weather forecasting, due to the growing use of technologies vulnerable to space weather hazards. However, refining the current models requires a more detailed understanding of solar-terrestrial relations, especially during extreme events such as magnetic clouds (MCs) which drive the fiercest storms at Earth. To this end, FRoST will investigate a previously unexplored aspect of the interaction of MCs with the terrestrial environment: the role played by the foreshock, a turbulent region extending upstream of the Earth's bow shock. The objectives of FRoST are (1) to characterise the foreshock properties during MC events, (2) to investigate how these alter in turn the properties of the region at the interface between the solar wind and the magnetosphere, the magnetosheath, and (3) assess whether the influence of the foreshock can be significant and thus should be included in space weather models. To undertake this challenging task, we will take on an interdisciplinary approach, combining numerical simulations and spacecraft observations. This project is now made possible by the extensive datasets acquired in the recent years and by the pioneering Vlasiator simulation, developed by the Host Group, which is the world's only global hybrid-Vlasov simulation and offers an unprecedented description of the near-Earth environment. Through FRoST, the Experienced Researcher (ER) will develop her skills in numerical physics, while bringing to the Host Group her expertise in data analysis. This diversification of her competencies will significantly increase the ER's career prospects. The Supervisor's strong record of scientific excellence and experience in mentoring early-career researchers will further ensure the successful execution of FRoST. This project has the potential to reinforce the position of Europe at the forefront of numerical space physics, and will contribute to the European efforts in space weather forecasting.";191325,6;191325,6;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;HELSINGIN YLIOPISTO;FI;ILMATIETEEN LAITOS;FI;;1;0;0;1;0;0 200927;701238;AFROEUROPOLITANS;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Cosmopolitanism Revisited: Afro-European Mobilities in Contemporary African Diasporic Literatures;2017-04-01;2019-03-31;;African literatures attest not only to the diversity of mobilities typical of the global era, but also to the fact that Europe continues to occupy a special place in the African literary imaginary. This study analyses the ways in which African Franco- and Anglophone diasporic literatures address the idea(l) of a cosmopolitan world citizenry in varied Afro-European contexts of mobility. In order to do so, the study critically revisits the concept of cosmopolitanism and, by drawing on theory and readings of African fiction, develops a new analytical pattern reflecting the privileged, practical and critical dimensions of the concept. The study’s interdisciplinary theoretical framework consists of postcolonial theory, cosmopolitanism, mobility studies and diaspora studies, and it applies a method of contextual close-reading which is motivated by a transnational impulse. By focusing on Afro-European mobilities, the study contributes to the topical scholarly endeavour of analysing the intertwinement of the two continents in a way that exceeds national boundaries. Studying fictional African cosmopolitanisms enhances our understanding of Europe in a changing global setting in terms of cultural encounters viewed from an Afro-European perspective, providing a literary articulation of the social exclusion that people with African origins often face in their attempt to claim cosmopolitan world citizenry in Europe. Fictive African mobile narratives are informed by such intersecting markers of difference as class, gender, nationality, and race. The study draws attention to how the universalising tendencies of traditional cosmopolitanisms and the elitism of some recently formulated Afropolitanisms are challenged in this setting. By developing and applying an analytical pattern of cosmopolitanisms, the study responds to the urgent call to revisit the slippery concept of cosmopolitanism by exploring its limits and potentials within the African literary context.;172800;172800;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;UNIVERSITE DE LIEGE;BE;;;;1;0;0;1;0;0 199420;690925;Phoenix;SIGNED;H2020-EU.1.3.3.;MSCA-RISE-2015;H2020;People for tHe eurOpean bioENergy mIX;2015-12-01;2019-11-30;;The development and adoption of renewable and sustainable forms of energy has become a major priority for Europe and is an important theme in H2020. Research into new, energy-related technologies to reduce Europe’s reliance on non-renewable fossil fuels is a critical need, and requires more newly qualified people in areas such as renewable-energy infrastructure management, new energy materials and methods, as well as smart buildings and transport. Bio-energy is particularly relevant to the Work Programme, because it is at the crossroads of several key European policies – from the Strategic Energy Technology Plan Roadmap on Education and Training (SET-Plan) to the European Bio-economy Strategy for European Food Safety and Nutrition Policy. So far, technological development has concentrated on using crops and wood for fuel, energy and industrial products. These conventional bio-resources are, however, limited, and the use of nonconventional, currently unused or under-utilised bio-resources provides the best possibility for the growth of the bioeconomy. However, European development in this priority field is failing to keep pace with demand due to a lack of qualified personnel, a lack of cohesion and integration among stakeholders, and poorly developed links between professional training and the real needs of industry. Based on seven work packages the Phoenix RISE project will address these issues by exploiting the complementary expertise of its partners and creating synergies between them through the targeted secondments of staff to advance research and innovation knowledge in bio-energy research. Phoenix is an international, interdisciplinary, cross-sectorial project, bringing together a total of 16 partners: 14 from the EU (5 companies and 9 academic organisations) and two Third-Country academic partners to enhance its collective research excellence and create new, post-graduate-level research training in key disciplines that support the provision of bio-energy.;1377000;1377000;H2020-MSCA-RISE-2015;/MSCA-RISE;EUROPEAN SUSTAINABLE ENERGY INNOVATION ALLIANCE - ESEIA, VEREIN FUR FORDERUNG DER EUROPAIESCHEN INNOVATION FUR ERNEUERBARE ENERGIEN;AT;"UNIVERSITE DE LIEGE;TECHNISCHE UNIVERSITAET GRAZ;INSTITUT POLYTECHNIQUE DE GRENOBLE;UNIVERSITEIT TWENTE;Laboratorio Nacional de Energia e Geologia I.P.;UNIVERSITY OF ZAGREB - FACULTY OF FOOD TECHNOLOGY AND BIOTECHNOLOGY - UZAG PBF;TORRES & BELO SA;BERGISCHER ABFALLWIRTSCHAFTSVERBAND;ASOCIATIA GREEN ENERGY;ENERGIE AGENTUR STEIERMARK GEMEINNUTZIGE GMBH;BRP-POWERTRAIN GMBH & CO KG;SVEUCILISTE U ZAGREBU, FAKULTET STROJARSTVA I BRODOGRADNJE;LAPPEENRANNAN-LAHDEN TEKNILLINEN YLIOPISTO LUT";"BE;AT;FR;NL;PT;HR;DE;RO;FI";;1;0;0;1;0;0 209378;752436;Demeco;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Default meanings in compound interpretation;2017-10-01;2018-09-30;;Languages always change, and existing words are constantly combined into novel combinations such as ‘trout pout’ or ‘bucket list’. Surprisingly, little is known about the actual processes and resources humans use to understand these novel combinations. This project will investigate a central question in the field of linguistics, namely the extent to which people rely on inherent meanings of words in combination (lexical semantics), compared with the extent to which they infer meaning from context (pragmatics). The interdisciplinary nature of the project is strong. It will use a combination of psycholinguistic techniques, with big data from corpus linguistics to empirically test hypotheses derived from state-of-the-art accounts in theoretical linguistics. Firstly, a questionnaire study will establish the extent to which people vary in their interpretation of different noun-noun combinations, and what determines the degree of variation. The study will innovatively use a large semantically annotated dataset to generate representative experimental items. Secondly, advanced eye-tracking technology will be used to investigate how these combinations fare when presented in contexts that either support or do not support a dominant interpretation. Together, the results of the two studies will shed light on the balance of word meaning and context in the interpretation of new combinations and either confirm or refute the underlying assumptions of competing semantic theories. The results will be of benefit in applications such as the automatic processing and translation of human language, and the assessment of misleading language usage, e.g. in advertising. They will also benefit theoretical linguists and psycholinguists, by showing how insights from each area can fruitfully be applied to the other. For the researcher, the project offers an invaluable opportunity to train in cutting-edge empirical techniques and gain skills in public engagement and research communication.;97727,4;97727,4;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;ANGLIA RUSKIN UNIVERSITY HIGHER EDUCATION CORPORATION;UK;;;;1;0;0;1;0;0 197914;667156;RegulHox;SIGNED;H2020-EU.1.1.;ERC-ADG-2014;H2020;Topological organization of vertebrate regulatory landscapes: The Hox genes paradigm;2015-09-01;2020-08-31;;The aim of this grant is to understand how mammalian developmental genes, which are usually pleiotropic, are controlled via long-range regulations and how chromatin partitions into large and discrete regulatory domains, generally matching Topologically Associating Domains (TADs). We want to understand how such domains emerged in evolution, how they are built during development and how they help implement enhancer functions. We will use a large genomic interval in mouse chromosome 2 containing the HoxD cluster as a paradigm, as it is covered by a large allelic series re-organizing the topology of this interval. Since the syntenic human locus (2q31) is affected in numerous genetic syndromes involving CNVs or large DNA re-arrangements, we believe this work will also help understand the mechanistic bases of human regulatory mutations. The approach will capitalize on our knowledge of mouse embryos, the implementation of cutting-edge genomic technologies and the unique collection of engineered mammalian chromosomes kept into living mice, which represent as many targeted re-organizations of both chromatin and regulatory topologies. It will require important technological development, in order to apply to mammalian embryos, methods (HiC) currently used for cell cultures or adult tissues. We think that the feasibility of this novel program is high, due the portfolio of experimental tools recently developed in our laboratory. Also, pilot experiments have been initiated to identify problems and preliminary results including the use of HiC on embryonic tissues suggest that the proposed experiments can be realized within delay. The novelty and originality of this program are in the interdisciplinary and system approach of genomic re-arrangements, as analyzed in vivo using recently developed methodologies, allowing to associate topological variations with regulatory modalities in a physiological context, during normal or genetically impaired embryonic development.;2499628;2499628;ERC-2014-ADG;/ERC-ADG;ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE;CH;;;;1;0;0;1;0;0 195166;655761;EXTREME;TERMINATED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Do extreme climatic events facilitate plant invasions?;2016-04-01;2018-09-30;;Extreme climate events (ECEs) are projected to increase in magnitude and frequency as global warming intensifies the global water cycle. Global warming is also changing species distribution patterns by affecting native plant communities and by enabling alien species to expand beyond their native range. We increasingly realize that climate change and biological invasions act together, leading to even more dramatic outcomes. However, how ECEs will affect the incidence and strength of biological invasions remains poorly understood. Therefore, the overall objective of EXTREME is to develop a mechanistic understanding of how increased climatic variability and ECEs affect alien plant invasions. I will relate the incidence of species invasiveness with climate variability and the occurrence of ECEs, using drylands as study system. A novel approach to develop further understanding is the inclusion of genomic features in explaining the response to ECEs. A modelling approach will be combined with a common-garden experiment to study the effect of drought and heavy rainfall on the performance of native and alien plant species in a model dryland system in South Africa. EXTREME will allow me to diversify my individual competence by acquiring new skills (statistical and climate modelling and GIS) and competencies (academic leadership, proposal writing, project management). EXTREME will strongly benefit my inter-sectoral and interdisciplinary expertise and strengthen my international network, which is also beneficial for the host. A two-way transfer of knowledge is guaranteed since EXTREME combines my expertise in invasion and evolutionary ecology with the host’s expertise in the effect of climate variability and extremes. Therefore, EXTREME is not only expected to catalyse my career development, but will contribute to Europe’s knowledge-based economy and society by providing invaluable knowledge on climate change and invasive species that is of the highest priority in the EU.;177598,8;177598,8;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;WAGENINGEN UNIVERSITY;NL;;;;1;0;0;1;0;0 209495;725232;BAPS;SIGNED;H2020-EU.1.1.;ERC-2016-COG;H2020;Bayesian Agent-based Population Studies: Transforming Simulation Models of Human Migration;2017-06-01;2021-05-31;;"The aim of BAPS is to develop a ground-breaking simulation model of international migration, based on a population of intelligent, cognitive agents, their social networks and institutions, all interacting with one another. The project will transform the study of migration – one of the most uncertain population processes and a top-priority EU policy area – by offering a step change in the way it can be understood, predicted and managed. In this way, BAPS will effectively integrate behavioural and social theory with modelling. To develop micro-foundations for migration studies, model design will follow cutting-edge developments in demography, statistics, cognitive psychology and computer science. BAPS will also offer a pioneering environment for applying the findings in practice through a bespoke modelling language. Bayesian statistical principles will be used to design innovative computer experiments, and learn about modelling the simulated individuals and the way they make decisions. In BAPS, we will collate available information for migration models; build and test the simulations by applying experimental design principles to enhance our knowledge of migration processes; collect information on the underpinning decision-making mechanisms through psychological experiments; and design software for implementing Bayesian agent-based models in practice. The project will use various information sources to build models bottom-up, filling an important epistemological gap in demography. BAPS will be carried out by the Allianz European Demographer 2015, recognised as a leader in the field for methodological innovation, directing an interdisciplinary team with expertise in demography, agent-based models, statistical analysis of uncertainty, meta-cognition, and computer simulations. The project will open up exciting research possibilities beyond demography, and will generate both academic and practical impact, offering methodological advice for policy-relevant simulations.";1455590;1455590;ERC-2016-COG;/ERC-COG;UNIVERSITY OF SOUTHAMPTON;UK;UNIVERSITAET ROSTOCK;DE;;1;0;0;1;0;0 206122;702189;IACG-QFIIs;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Institutional Activism in Corporate Governance: Qualified Foreign Institutional Investors in China;2016-10-04;2018-10-03;;Qualified Foreign Institutional Investors (QFIIs) potentially import practices of shareholder activism that can improve corporate governance in emerging economies’ stock markets. This proposal will scrutinize this proposition in the context of China. To do this, it explores the impact of QFIIs’ institutional activism, especially European QFIIs, on corporate governance in Chinese listed companies both in theory and in practice using the interdisciplinary methods of an economic analysis of law and quantitative analysis. The first objective is to conduct a theoretical analysis on the motivations behind QFIIs’ investments and their behavior as shareholders, supported by an analysis of data on companies targeted by QFIIs between 2003 and 2015. The aim is to find out whether QFIIs engage in shareholder activism in corporate China, especially following Chinese policy changes in relation to the regulation of QFIIs in 2006 and 2012. The Second objective is to conduct an empirical study by way of event study and multiple regression on the correlation between QFIIs stock-targeting/stockholding and the performance of Chinese listed companies over the same period, in order to identify the effectiveness of QFIIs’ institutional activism in improving corporate governance in Chinese listed companies. The working hypothesis of this proposal is that QFIIs may not engage in activism because of the speculative nature of institutional investors, and therefore that policy changes of 2006 and 2012 may not have enhanced QFIIs’ activism in corporate China. This suggests that further policy changes may be required, both in China and in Europe, if QFIIs are to engage in activism which benefits both China and their end beneficiaries. An appropriate set of policy recommendations will be identified and addressed to policymakers and investors in both China and EU.;183454,8;183454,8;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;THE UNIVERSITY OF SHEFFIELD;UK;;;;1;0;0;1;0;0 195909;660205;ISPADMEC;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Integrin specificity in rigidity sensitive proliferation, activation and directional migration of endothelial cells;2015-09-01;2018-06-26;;"Cells have the extraordinary ability to regulate their morphology, functions and fate to minimal changes in the extracelullar microenvironment. Through multi-protein, cell-matrix adhesions they are able to recognize and respond not only to the chemical diversity of the extracellular matrix (ECM), but also to its physical and topographical features. Mechanical and structural cues encoded in the ECM have an essential role in healthy tissue function where contractility, spreading and proliferation are intricately regulated by cell-cell and cell-matrix adhesion and tension. Unsurprisingly, abnormal ECM mechanics are directly associated with disease and tissue malformation (atherosclerosis, wound healing and tumor formation). Understanding the mechanisms cells use to sense and transduce mechanical signals, as well as the contribution of key players in the process is a pressing, unmet challenge. To achieve this goal, I here propose the development of an in vitro strategy that allows precise regulation of both biochemical and mechanical parameters in order to isolate their contribution on fundamental endothelial cell (EC) functions. The proposed work will exploit advances in materials science and nanotechnology to modulate with high precision the presentation of highly selective integrin ligands at the nanometer and micrometer length scales, on substrates with tunable viscoelasticity and mechanics. The anticipated effects of integrin engagement and substrate mechanics on ECs will shed light on how the microenvironment affects their proliferation, activation and directional migration, and help correlate these finding with pathological scenarios where blood vessel mechanics and EC integrin expression are deregulated. In summary, the proposed interdisciplinary approach will contribute both advanced tools to study cells in vitro and crucial answers for specific questions relating to EC biology.";171460,8;171460,8;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;DE;;;;1;0;0;1;0;0 197224;637647;IDEM;SIGNED;H2020-EU.1.1.;ERC-StG-2014;H2020;Immunity, DEvelopment and Microbiota: Understanding the Continuous Construction of Biological Identity;2015-09-01;2020-08-31;;"The problem of biological identity (what counts as one individual organism, and what makes each individual organism “the same” though it constantly changes through time?) has a long history both in philosophy and in science. Recent data coming from immunology, microbiology and developmental biology may revolutionize our conception of the construction of biological identity through time, by showing that this construction depends crucially on environmental factors and, most importantly, on a constant dialogue with symbiotic microorganisms integrated into the organism. IDEM, a fundamentally interdisciplinary project at the interface between philosophy and biology, aims at: i) determining to what extent it is adequate to see this shift as an ongoing “microbial revolution” in today’s biology; ii) understanding the exact processes by which developmental processes in organisms depend on microbial symbionts; iii) asking whether the role of the immune system (usually seen as a system that rejects genetically foreign elements from the body) in the maintenance of the organism needs to be reevaluated; iv) how traditional conceptions of biological individuality will be modified by this revolution. If funded, this project will provide a new understanding of the way living things are continuously constructed through time and interact with their biotic environment.";1454249,99;1454249,99;ERC-2014-STG;/ERC-STG;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FR;;;;1;0;0;1;0;0 209146;724949;WEALTHPOL;SIGNED;H2020-EU.1.1.;ERC-2016-COG;H2020;The Politics of Wealth Inequality and Mobility in the Twenty-First Century;2017-05-01;2022-04-30;;Over the past decade scholars across the social sciences have grappled with the causes and consequences of economic inequality and social mobility. Income inequality has risen to levels unseen for a century. At the same time, economies in Europe and beyond have seen an even larger concentration in wealth, along with unprecedented volatility in asset markets such as housing and equities. These changes in the distribution of wealth have been of great economic and political consequence, with the debates over housing, inheritance, and capital taxation shaping contemporary political discourse. Yet, scholars of political economy remain beholden to analyses of inequality and mobility that examine only the flows of income in the labour market and ignore inequality and mobility in the stock of wealth held by citizens. WEALTHPOL is a ground-breaking interdisciplinary project with a series of three high-risk and novel work packages that transform our knowledge about wealth inequality and wealth mobility. WEALTHPOL 1 develops the first comprehensive collection of data about the distribution and inheritance of wealth in Europe and beyond. WEALTHPOL 2 provides the first political database of how governments shape the pattern of wealth through political pledges and policymaking, spanning seven decades and thirty-seven countries. Finally, WEALTHPOL 3 uses cutting-edge laboratory and survey experiments to expand our knowledge about what citizens think about wealth. WEALTHPOL draws these three strands together by connecting policy environments and the distribution of wealth to citizens’ attitudes to wealth inequality and the kinds of policies that might shape it. In doing so, WEALTHPOL revolutionises our understanding of - and our capacity to respond to - the politics of capital in the twenty-first century in Europe and beyond.;1696109;1696109;ERC-2016-COG;/ERC-COG;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;UK;;;;1;0;0;1;0;0 208303;724046;SUCCESS;SIGNED;H2020-EU.1.1.;ERC-2016-COG;H2020;The earliest migration of Homo sapiens in Southern Europe: understanding the biocultural processes that define our uniqueness;2017-05-01;2022-04-30;;"Anatomically modern humans (AMHs) radiated out of Africa into the rest of the world around 60,000-50,000 years ago. While various evidence suggests arrivals of AMHs in Asia and Australia ca. 45,000 calendar years before present (cal BP), the timing and pattern of the biological and cultural shifts that occurred in Europe around 50,000 to 35,000 cal BP, are hotly debated and are considered to be among the most important questions in paleoanthropology. This period documents 1) the demise of the autochthons Neandertals and their replacement by AMHs as well as 2) dramatic changes in human behaviour and the appearance of various technocomplexes that replaced pre-existing Mousterian cultures. Debate revolves around the question of whether modern behaviour was independently achieved by Neandertals or is directly related to the arrival of AMH. In this context Italy plays a pivotal role due to its geographic position and ecological variability, and key archaeological sites with transitional and early Upper Paleolithic cultures. This interdisciplinary and multidisciplinary project aims to understand when AMHs arrived in Southern Europe, the biocultural processes that favoured their successful adaptation and the final cause of Neandertal extinction. The project involves survey in Italy and field investigations of key archaeological sites dating to the Middle-to-Upper Paleolithic Transition, paleoecological, zooarchaeological, paleoanthropological and isotope analyses, studies of pigments, ornaments, lithic and bone tools, as well as statistical modeling using cutting-edge protocols. The results of this work will be of pivotal importance for understanding a key period in European prehistory and, more generally, the biocultural, adaptive and ecological characteristics that make our species successful and unique. It implies that this project will be crucial for understanding the replacement of all hominin species by AMHs around the world.";1993811;1993811;ERC-2016-COG;/ERC-COG;ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA;IT;;;;1;0;0;1;0;0 201059;702612;OEMBS;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Out-of-equilibrium entangled many-body systems;2016-09-01;2018-08-31;;"The quest for a complete understanding of out-of-equilibrium behaviors in entangled many-body systems is a fundamental challenge in contemporary physics. In contrast with equilibrium, where several effective approaches (based on low-energy approximations) are available, there is no effective framework to describe out-of-equilibrium phenomena yet. One has then to rely only on numerical methods, such as the time-dependent Density Matrix Renormalization Group (tDMRG). In this context, the goal of the project is to clarify fundamental aspects of out-of-equilibrium physics in strongly-entangled systems, both in one and in two dimensions. The proposed research pursues a very interdisciplinary approach, by combining state-of-the-art entanglement-based numerical tools, as well as exactly-solvable models. Specifically, in one dimension the project aims at developing a better numerical and analytical framework to: i) simulate the full out-of-equilibrium dynamics in integrable models, merging Monte Carlo and Bethe ansatz techniques; ii) understand the out-of-equilibrium behavior of many-body continuous systems, employing the framework of tensor network techniques (continuous matrix product states); iii) understand the interplay between disorder and integrability in many-body localized phases of matter. Finally, in two dimensions the aim of the project is to characterize the out-of-equilibrium signatures of topological order in quantum spin liquids, with special attention to the comparison with recent experimental results.";168277,2;168277,2;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;SCUOLA INTERNAZIONALE SUPERIORE DI STUDI AVANZATI DI TRIESTE;IT;;;;1;0;0;1;0;0 199691;658496;MemoMCI;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Targeting reconsolidation to strengthen memories in individuals with Mild Cognitive Impairment;2016-09-01;2018-08-31;;Memory for unique personal experiences (episodic memory) is critical to daily life functioning. This form of long-term memory also displays the largest degree of age-related decline. This condition is accelerated in amnestic mild cognitive impairment (aMCI), which is often the precursor for emerging Alzheimer’s disease (AD). Since AD produces tremendous chronic burdens on individuals, families and health care systems around the world, the development of effective therapeutic interventions to prevent or delay AD is an urgent international priority. Noninvasive brain stimulation with transcranial direct current (tDCS) has demonstrated efficacy in enhancing long-term memory in healthy human subjects. In addition, reactivation of consolidated memories triggers reconsolidation, a time-limited period during which existing memories can be strengthened. Recent reconsolidation studies in healthy young and older adults have shown that noninvasive stimulation of the prefrontal cortex (PFC) significantly strengthens existing verbal episodic memories. In this double-blind, placebo-controlled study, I test the hypothesis that facilitatory tDCS over the PFC will strengthen existing verbal memories through reconsolidation in individuals with aMCI. In addition, I will determine specific biomarkers to help identify individuals who benefit the most from this tDCS intervention based on variations in brain structure or presence of genetic polymorphisms. These data will provide preliminary information that is crucial for the design of multicentre, longitudinal, placebo-controlled clinical trials, which are needed to validate this novel experimental intervention. This fellowship will provide me with the training in neurorehabilitation, the possibility to learn new skills (neuroimaging and genetics) through secondments, and the opportunity to build the interdisciplinary collaborations I need to become an independent and successful scientist in the field of neuroplasticity.;168277,2;168277,2;H2020-MSCA-IF-2014;/MSCA-IF-EF-RI;CASA DI CURA PRIVATA DEL POLICLINICO SPA;IT;;;;1;0;0;1;0;0 220362;825430;NANOSMART;SIGNED;H2020-EU.2.1.1.;ICT-07-2018;H2020;NANO components for electronic SMART wireless systems;2019-01-01;2021-12-31;;In the modern world everything goes wireless and everyone goes mobile. To sustain this trend, higher frequency, smaller, more complex analogue electronics with beam steering capabilities are needed. The objective of NANOSMART is to develop technology for future generation, smart monolithic Transmit / Receive front-end ICs capable of RF switching, power management, high efficiency, at a fraction of the footprint and cost of current solutions. NANOSMART addresses this need by developing a new technological platform based on CNT and 2D material electronics (the two most promising technologies to replace Silicon electronics in the future). NANOSMART develops unique concepts already proven by the consortium such as deep sub-wavelength antennae, CNT NEMS for RF switching, nano electromechanical reconfigurable filters and multiple FET technologies. Monolithic integration of all technologies mentioned above will provide a compact platform including new amplifier architecture, power management, RF switching and antennae on one monolithically integrated chip. Within the front-end IC, three sensor types (Temperature humidity and RF radiation built from novel technology) will also be integrated to provide smart, autonomous system reaction and thus improve accuracy, power efficiency and real-time system health monitoring and on-the-fly response to ambient conditions. The two demonstrators planned are aiming at high end radar and mass market IoT applications providing this level of smart functionality for the first time. NANOSMART encompasses extensive design, modelling and advanced characterization techniques to provide the tools for fast industrial take-up of the developed technology. The project’s interdisciplinary consortium is made up of 10 partners from 7 countries with a wide geographical spread (France, Sweden, Ireland, Italy, Romania, Greece, and Spain) and includes a global industrial player, two SMEs and top EU academic and research institutions.;3999890;3999890;H2020-ICT-2018-2;/RIA;THALES SA;FR;"ECOLE SUPERIEURE DE PHYSIQUE ET DECHIMIE INDUSTRIELLES DE LA VILLE DEPARIS;RF MICROTECH SRL;FUNDACIO INSTITUT CATALA DE NANOCIENCIA I NANOTECNOLOGIA;FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS;SHT SMART HIGH-TECH AB;INSTITUTUL NATIONAL DE CERCETAREDEZVOLTARE PENTRU MICROTEHNOLOGIE;UNIVERSITA POLITECNICA DELLE MARCHE;UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK;CHALMERS TEKNISKA HOEGSKOLA AB";"FR;IT;ES;EL;SE;RO;IE";;1;0;0;1;0;0 220392;793554;EcoSpy;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Leveraging the potential of historical spy satellite photography for ecology and conservation;2018-12-01;2020-11-30;;Conservation planning and action critically relies on information about dynamics in ecosystems, habitats, and species’ populations in order to define baselines, set conservation targets, and to identify areas for protection and restoration activities. Following the opening of the Landsat archives, remote sensing became a key technology for providing information to conservation, but many world regions experienced widespread changes in habitats and species populations prior to the Landsat history (1980s). In EcoSpy we propose to pioneer the broad-scale use of recently declassified historical, global, high-resolution spy satellite photographs from the Cold War era (Corona) to extend the temporal scale of ecological and conservation remote sensing studies as far back as the 1960s. We will integrate Corona with Landsat and GoogleEarth Images in three proof-of-concept studies to test the usability of Corona for conservation research and applications. We will assess changes in (1) ecosystems of conservation concern, by identifying long-undisturbed forests and their fragmentation in Romania, (2) endangered species habitats, by analyzing saiga antelope habitat in Kazakhstan, and (3) keystone species’ population dynamics, by analyzing population density of steppe marmots in Kazakhstan. Additionally, we will carry out a synthesis study on uses and benefits of Corona imagery for ecology and conservation worldwide. EcoSpy is deeply interdisciplinary, located at the intersection of ecology, conservation science and remote sensing. Scientifically, EcoSpy will enhance the long-term understanding of ecological processes such as fragmentation, range shifts and population dynamics, and will extend availability of high resolution remotely sensed data by two decades prior to Landsat. EcoSpy will inform conservation action such as identifying priority conservation areas and defining conservation baselines for vulnerable habitats and species, advancing conservation and ecology worldwide.;171460,8;171460,8;H2020-MSCA-IF-2017;/MSCA-IF-EF-RI;HUMBOLDT-UNIVERSITAET ZU BERLIN;DE;;;;1;0;0;1;0;0 209214;746155;ANXINT;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;ANXIETY IN INTERNATIONAL POLITICS: MEDIATING EFFECTS OF NORMS;2017-08-01;2019-07-31;;This interdisciplinary research project examines how anxiety impacts individual –level political attitudes toward international issues, and in turn how prevalence of anxiety interacts with nativist and cosmopolitan norms in shaping international political attitudes. Bridging the fields of International Relations (IR), Psychology, and Philosophy, the research project will contribute to the distinct but related literatures on ontological security, emotions, and norms in IR with a systematic analysis of anxiety. In its outgoing phase at the University of British Columbia, the research will focus on the development of a novel conceptual/ analytical framework linking anxiety, norms, narratives and international political attitudes drawing primarily on existentialist philosophy and terror management theory in psychology. In the second phase at University of Columbia and the third phase at Koc University, the research will derive comparative cross-cultural findings from experimental analyses conducted with university students at UBC in the outgoing phase and at Koc University (KU) in the reintegration phase.;157734;157734;H2020-MSCA-IF-2016;/MSCA-IF-GF;KOC UNIVERSITY;TR;;;;1;0;0;1;0;0 210303;746133;WoRD-DoME;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Women's Economic Rights and Cultural Difference: Defining Development for the Middle East;2017-07-01;2018-09-30;;"This research focuses on tensions between discourses of multiculturalism and women’s economic rights and the processes in which they arise in development institutions and programs. While the multidisciplinary literature on development unpacks public declarations by development institutions and studies the local implementation of development programs, it evades two crucial questions: conditions of agency formation and inequality in institutional processes, and the role assumptions about cultural difference play in development paradigms. This research fills these gaps by exploring how issues of women’s economic rights and notions of cultural difference are negotiated inside development institutions and reflected in their programs. The research deploys two data collection strategies, longitudinal content and discourse analysis of relevant development reports and interviews with gender experts with work experience on the Middle East. It will be conducted at the Gender Centre of the Graduate Institute of International and Development Studies, under the supervision of Professor Elisabeth Prügl, a best fit for the project given the rich array of gender and development scholarship at the Centre, its established networks with the multilateral actors in Geneva and beyond, and the two scholars’ mutual interests in the area of gender expertise and gender equality. It is an interdisciplinary project, informed by relevant studies in the fields of anthropology, sociology and political science, and has significant potential to contribute development studies and feminist political economy. It builds on the researcher’s experience in the field of gender and development, the Middle East and transnational networks. It expands her research to international gender experts in development; grows her expertise on the Middle East; and enlarges her fieldwork scope to Europe. The training, networking and publication prospects put her on a firm path toward professorship.";117137,25;117137,25;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;FONDATION POUR L INSTITUT DE HAUTES ETUDES INTERNATIONALES ET DU DEVELOPPEMENT;CH;;;;1;0;0;1;0;0 197857;647234;SELECTION;SIGNED;H2020-EU.1.1.;ERC-CoG-2014;H2020;Improving Educational Outcomes by Transforming the Selection of Future Teachers;2015-09-01;2020-08-31;;"The most effective way of improving education systems is to improve the quality of teachers; a fundamental step to improve the quality of teachers is to select candidates for training who possess the 'soft skills' or non-cognitive traits and attributes that are related to effective teaching. Prof. Robert Klassen’s research will draw on interdisciplinary educational and occupational psychology frameworks to develop an evidence-based teacher training selection approach based on an innovative situational judgment test (SJT) methodology. This is ground-breaking research, as current selection procedures are ad hoc with little or no theory grounding or evidence of predictive validity. The project will dramatically improve the accuracy of the teacher candidate selection process, build understanding of the short- and long-term predictive validity of the non-cognitive attributes of prospective teachers, and provide system-wide educational improvements by increasing the quality of candidates entering teacher training programs. The ERC funding presents an opportunity for a novel high-rewards approach to applied educational psychology research that has the potential to markedly improve teacher quality and educational outcomes.";1400214;1400214;ERC-2014-CoG;/ERC-COG;UNIVERSITY OF YORK;UK;;;;1;0;0;1;0;0 220299;801809;GEoREST;SIGNED;H2020-EU.1.1.;ERC-2018-STG;H2020;predictinG EaRthquakES induced by fluid injecTion;2019-02-01;2024-01-31;;Fluid injection related to underground resources has become widespread, causing numerous cases of induced seismicity. If felt, induced seismicity has a negative effect on public perception and may jeopardise wellbore stability, which has led to the cancellation of several projects. Forecasting injection-induced earthquakes is a big challenge that must be overcome to deploy geo-energies to significantly reduce CO2 emissions and thus mitigate climate change and reduce related health issues. The basic conjecture is that, while initial (micro)seisms are caused by well-known mechanisms that could be predicted, subsequent activity is caused by harder to understand and, at present, unpredictable coupled thermo-hydro-mechanical-seismic (THMS) processes, which is the reason why available models fail to forecast induced seismicity. The objective of this project is to develop a novel methodology to predict and mitigate induced seismicity. We propose an interdisciplinary approach that integrates the THMS processes that occur in the subsurface as a result of fluid injection. The methodology, based on new analytical and numerical solutions, will concentrate on (1) understanding the processes that lead to induced seismicity by model testing of specific conjectures, (2) improving and extending subsurface characterization by using industrial fluid injection operations as a long-term continuous characterization methodology, so as to reduce prediction uncertainty, and (3) using the resulting understanding and site specific knowledge to predict and mitigate induced seismicity. Project developments will be tested and verified against fluid-induced seismicity at field sites that present diverse characteristics. Arguably, the successful development of this project will provide operators with concepts and tools to perform pressure management to reduce the risk of inducing seismicity to acceptable levels and thus, improve safety and reverse public perception on fluid injection activities.;1438201;1438201;ERC-2018-STG;/ERC-STG;AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS;ES;;;;1;0;0;1;0;0 220310;804259;HANDLING;SIGNED;H2020-EU.1.1.;ERC-2018-STG;H2020;Writers handling pictures: a material intermediality (1880-today);2019-07-01;2024-06-30;;"Not only does the writer’s hand hold the pen, it manipulates pictures as well. Writers touch, hoard, cut, copy, pin and paste various kinds of pictures and these actions integrate literature in visual culture in many ways that have never been tackled as a whole before. Some writers spent their life surrounded by pictures taken from magazines, creating an inspirational environment; yet others nurtured their imagination with touristic leaflets and visual advertisements; others created fictional characters based on collected portraits. What do writers do with pictures? How does literature stage the pictures handled? From very concrete and banal uses of pictures will emerge a new vision of literature as intermediality in action. This investigation applies the tool set of visual anthropology and visual studies to writers for a deeper understanding of visual ecosystems. Covering a large period, from the beginning of mass reproduction in the 1880s and the digital practices of today, HANDLING focuses on the French and French-speaking field and stands as a laboratory to refashion a broader model for relationships between image and text. Its main challenge is to get to the root of contemporary iconographic practices. HANDLING is unconventional because literary studies usually focus on the text: contrary to the norm, it sets the image at the very centre of the literary act. This approach might yield promising results for the visibility of literature in the future, especially in exhibitions. Making these practices visible will make literature itself more visible. As an internationally recognized specialist of text-image relationships with an in-depth knowledge of French/Belgian literature and photography, I will build a team and lead this 5-year ambitious project. Grounded in interdisciplinarity, it will show the significant and unexpected role of literature in material visual culture.";1500000;1500000;ERC-2018-STG;/ERC-STG;UNIVERSITE CATHOLIQUE DE LOUVAIN;BE;;;;1;0;0;1;0;0 220334;813545;HELICAL;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2018;H2020;HEalth data LInkage for ClinicAL benefit;2019-01-01;2022-12-31;;"European researchers have made leading contributions to the large genomic, transcriptomic and clinical datasets from patients with chronic diseases. Advances in information science provide unprecedented opportunities for using these datasets to elucidate the complex biology of these disorders, its influence by environmental triggers, and to personalise their management. Currently, exploitation of these opportunities is limited by a shortage of researchers with the required informatics skills and knowledge of requisite data protection principles. HELICAL addresses this unmet need by developing a trans-sectoral and interdisciplinary training programme that builds on the expertise and existing collaborations of its partners. It provides 15 early stage researchers with training in analysis of large datasets, using autoimmune vasculitis as a paradigm as it is scalable, and as comprehensive biological and clinical datasets are already available. The HELICAL training program focuses on three complementary areas: application of informatics to such datasets to gain new biological insights; translation of these into practical clinical outputs and management of ethical constraints imposed on such studies. The programme will be delivered through a multidisciplinary, trans-sectoral partnership of Academic and Industry researchers with expertise in basic biomedical research, epidemiology, statistics, machine learning, health data governance and ethics. Therefore, HELICAL exploits recent advances in data science to link research datasets with longitudinal healthcare records, based on the robust ethical foundation required for linkage studies using near-patient data, to address key experimental questions. The results will have obvious potential for transforming healthcare in the field of autoimmune disease. The training provided addresses a key skills gap in the European workforce and should make the ESR eminently employable in academic, industrial and clinical sectors.";4050339,12;4050339,12;H2020-MSCA-ITN-2018;/MSCA-ITN-ETN;THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN;IE;"MEDIZINISCHE UNIVERSITAET WIEN;UNIVERSITE PARIS DIDEROT - PARIS 7;KUNGLIGA TEKNISKA HOEGSKOLAN;ANAXOMICS BIOTECH, S.L.;FUNDACION PRIVADA INSTITUTO DE SALUD GLOBAL BARCELONA;IBM IRELAND LIMITED;UNIVERSITY OF LEEDS;AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS;TISSUEGNOSTICS GMBH;FIRALIS;CONSORCI INSTITUT D'INVESTIGACIONS BIOMEDIQUES AUGUST PI I SUNYER;UNIVERSITY OF GLASGOW;THE EUROPEAN INSTITUTE FOR INNOVATION THROUGH HEALTH DATA";"AT;FR;SE;ES;IE;UK;BE";;1;0;0;1;0;0 220318;803860;MapModern;SIGNED;H2020-EU.1.1.;ERC-2018-STG;H2020;Social Networks of the Past: Mapping Hispanic and Lusophone Literary Modernity, 1898-1959;2018-12-01;2023-11-30;;"Data mining and big data approaches are changing the ways in which we create knowledge, access information and preserve our cultural heritage. This research applies cutting-edge technology to analyse a neglected aspect of European and non-European social and cultural life of the 20th century: the impact of Hispanic and Lusophone literary networks and cultural mediators in international modernity between 1898 and 1959. The project pursues three central goals: 1) to retrieve the lost history of Iberoamerican mediators in modernist intercultural and multilingual networks and reappraise their role; 2) to narrow the knowledge divide in terms of access and production in the Iberoamerican field by generating and making freely available new and reliable data that addresses the lack of documented cultural heritage, and 3) to offer an innovative and reproducible model that can be applied across periods, languages, and disciplines to analyse cross-border phenomena, under-examined mediators and networks and overshadowed geographical scales in their relations to the wider world. These goals will be achieved by a twofold methodology: i) an open and collaborative research tool providing a data source for quantitative and qualitative analysis on Iberoamerican mediators, and ii) four subprojects on key cultural transformation processes distinctive of modern societies (the institutionalization of Iberoamerican cultures, the rise of translated literature in key Iberoamerican modernist journals, the position of Iberoamerican women in the cultural field, and the role of Iberoamerican mediators in new forms of mass media). By combining computational methods, cultural, literary history, translation, sociology, gender and media studies, I will lead an interdisciplinary team of 6 researchers that will fill the gap in modernist studies and will offer an original, reproducible and empirically tested method for studying social human interaction within a global, cultural and decentred approach";1500000;1500000;ERC-2018-STG;/ERC-STG;FUNDACIO PER A LA UNIVERSITAT OBERTA DE CATALUNYA;ES;;;;1;0;0;1;0;0 220335;812765;NU-SPINE;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2018;H2020;Training innovative future leaders in research and development of materials and implants for the spine;2019-01-01;2022-12-31;;"This proposal aims to develop Early-Stage Researchers into innovative European leaders in biomedical engineering, with a focus on spinal devices. Synergies will be drawn from the involved high-quality research centres in the interdisciplinary fields of materials science, mechanical engineering and biology, which will permit acquiring expertise in the development and preclinical testing of such devices, with a focus on meeting current and future societal challenges related to implant longevity and biocompatibility. The training programme has been put together in close collaboration with the relevant industry, SME’s as well as larger enterprise, ensuring adequate exposure to these environments, through e.g. secondments, as well as a knowledge base permitting a seamless transfer into industry and fostering innovation. An expert in industrial engineering and management will undertake co-ordination of the innovation-related training as well as consist of an independent career coach to the young researchers. The growing elderly, more active population puts higher demands on implants, which need to last longer and provide an adequate biological response throughout their lifetime. Current solutions for the spine suffer from a variety of issues, such as implant subsidence as well as potentially detrimental metal ion release and wear products. The current proposal aims to provide alternatives to these, by developing novel materials and implants for the spine, which provide i) non-detrimental wear products and reduced metal ion release and/or ii) enhanced osseointegration. Since many implant failures can be linked to inadequate loading, considerable effort will be spent on developing methods that simulate more closely adverse and individual biomechanical environments, as well as adapting implant designs to these situations. Adequate biological response will be evaluated through in vitro and in vivo models, closing the circle of the pre-clinical testing value chain.";4274478;4274478;H2020-MSCA-ITN-2018;/MSCA-ITN-ETN;UPPSALA UNIVERSITET;SE;"CERAMTEC GMBH;IHI IONBOND AG;KEY ENGINEERING SOLUTIONS LIMITED;UNIVERSITY OF LEEDS;EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH";"DE;CH;UK";;1;0;0;1;0;0 220333;802182;Neurovulnerability;SIGNED;H2020-EU.1.1.;ERC-2018-STG;H2020;Molecular mechanisms underlying selective neuronal death in motor neuron diseases;2019-07-01;2024-06-30;;"The mechanisms behind neuronal death in different motor neuron diseases (MND) remain unknown. These MNDs include the devastating spinal muscular atrophy (SMA) and amyotrophic lateral sclerosis (ALS). A fascinating question in neurodegeneration research is why mutations in ubiquitously expressed genes result in the selective death of a specific neuronal subtype. The ubiquitously expressed and conserved survival of motor neuron (SMN) protein receives its name because its deficit results in MN degeneration. However, SMN known functions -spliceosome assembly and axonal mRNA transport- do not explain the selective MN vulnerability. Accumulation of intracellular aggregates in neurons is a hallmark of most neurodegenerative diseases. The lysosome-autophagy system is the main catabolic pathway for recycling of protein aggregates and damaged organelles, and its role as a quality control system is especially critical in neurons, due to their postmitotic and highly specialized nature. The hypothesis for this proposal is that SMN deficiency leads to a lysosome-autophagy dysfunction which results in a proteostatic failure, underlying MN degeneration. Furthermore, the existing heterogeneity in SMN protein levels across MN populations may determine their probability of survival. To test these hypotheses we will use the CRISPR/Cas9 system to genetically engineer human control, SMA and ALS patient-derived iPSCs to generate isogenic and reporter lines that will allow us to study selective neuronal subtypes at a single-cell level. We will also follow an interdisciplinary approach using a SMA Drosophila model to identify new molecular pathways essential for SMN neuropathology. Altogether, my research proposal aims at untangling the molecular mechanisms underlying selective MN death. Our results will open up new directions of research into the molecular basis of neurodegeneration and will provide clues for the design of therapeutics targeting specific neuronal types or phases of MNDs.";1472667,34;1472667,34;ERC-2018-STG;/ERC-STG;AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS;ES;;;;1;0;0;1;0;0 220320;801790;MOBILIZE;SIGNED;H2020-EU.1.1.;ERC-2018-STG;H2020;Improving health in people with multimorbidity: a paradigm shift in health care from disease-based curative models to personalized exercise therapy and self-management;2019-08-01;2024-07-31;;"The goal of this proposal is to support the paradigm shift in the health care of people with multiple chronic conditions in Europe from a focus on disease-based curative models to holistic person-centered self-care through personalized,supervised exercise therapy and education. The problem:The impact of multimorbidity on the individual and society is massive and much greater than the impact of single chronic conditions alone. However, effective treatments are missing and research and health care reinforce an inefficient and burdensome single-disease framework. The solution:Exercise has the potential to disrupt the ‘vicious cycle’ of systemic inflammation associated with chronic conditions and improve health in multimorbidity. A personalized exercise and education program aimed at supporting subsequent self-management by the individual will be developed in an interdisciplinary collaboration, building on evidence from biomarkers, patient involvement and methodological expertise. Self-reported,physiological and societal effects will be investigated in a randomized controlled trial comparing the personalized program with standard single-disease models of care. Scientific and public dissemination and implementation ensuring significant personal and societal benefit is fundamental to the proposal. The proposal is associated with high risk, as the current disease-based curative models involve treatment by several highly specialized health care providers, while the new person-centered self-management model is centered on a personalized program delivered by one health care provider. The ground-breaking nature of this proposal lies in its potential to revolutionize how health care is organized for people with multimorbidity, by giving them one primary care provider, and how we use non-surgical treatment in health care and science by bringing the concept of precision medicine into multimorbidity and utilizing it to improve treatment outcome with exercise therapy as the model.";1499230;1499230;ERC-2018-STG;/ERC-STG;SYDDANSK UNIVERSITET;DK;;;;1;0;0;1;0;0 220282;805201;METANICHE;SIGNED;H2020-EU.1.1.;ERC-2018-STG;H2020;Regulation of bone metastases by age-associated angiocrine signals;2019-01-01;2023-12-31;;Blood vessels form a versatile transport network and provide inductive signals called angiocrine factors to regulate tissue-specific functions. Blood vessels in bone are heterogeneous with distinct capillary subtypes that exhibit remarkable alterations with age. Bone is the most prevalent site of metastasis, and ageing is linked to the reactivation of dormant tumor cells (dorTCs) and metastatic relapse. Bone remodeling processes are also associated with metastatic relapse. Here, I will define the role of distinct vascular niches in regulating the fate of DTCs in bone. Finally, I will unravel the age-related angiocrine factors and identify key angiocrine signals that drive the reactivation of dorTCs. I will employ a powerful combination of advanced 3D, intravital, and whole body imaging, cell specific-inducible mouse genetics, transcriptional profiling and bioinformatics in an unprecedented manner to achieve my goals. New cutting-edge techniques such as advanced 3D and 4D bone imaging are important aspects of my proposal. I will also define the role of highly promising novel candidate age-related angiocrine signals with sophisticated inducible endothelial-specific humanised mouse models. My work will break new ground by unraveling a repertoire of age-related angiocrine factors and will contribute to a wider scientific community in bone, blood, and age-related diseases. This interdisciplinary work at the frontiers of bone, cancer and vascular biology will provide the first conceptual link between vascular ageing and bone metastasis and will contribute towards the development of therapeutic strategies for targeting DTCs in bone.;1496613;1496613;ERC-2018-STG;/ERC-STG;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;UK;;;;1;0;0;1;0;0 220096;815943;RADDICS;SIGNED;H2020-EU.1.1.;ERC-2018-COG;H2020;Reliable Data-Driven Decision Making in Cyber-Physical Systems;2019-01-01;2023-12-31;;"This ERC project pushes the boundary of reliable data-driven decision making in cyber-physical systems (CPS), by bridging reinforcement learning (RL), nonparametric estimation and robust optimization. RL is a powerful abstraction of decision making under uncertainty and has witnessed dramatic recent breakthroughs. Most of these successes have been in games such as Go - well specified, closed environments that - given enough computing power - can be extensively simulated and explored. In real-world CPS, however, accurate simulations are rarely available, and exploration in these applications is a highly dangerous proposition. We strive to rethink Reinforcement Learning from the perspective of reliability and robustness required by real-world applications. We build on our recent breakthrough result on safe Bayesian optimization (SAFE-OPT): The approach allows - for the first time - to identify provably near-optimal policies in episodic RL tasks, while guaranteeing under some regularity assumptions that with high probability no unsafe states are visited - even if the set of safe parameter values is a priori unknown. While extremely promising, this result has several fundamental limitations, which we seek to overcome in this ERC project. To this end we will (1) go beyond low-dimensional Gaussian process models and towards much richer deep Bayesian models; (2) go beyond episodic tasks, by explicitly reasoning about the dynamics and employing ideas from robust control theory and (3) tackle bootstrapping of safe initial policies by bridging simulations and real-world experiments via multi-fidelity Bayesian optimization, and by pursuing safe active imitation learning. Our research is motivated by three real-world CPS applications, which we pursue in interdisciplinary collaboration: Safe exploration of and with robotic platforms; tuning the energy efficiency of photovoltaic powerplants and safely optimizing the performance of a Free Electron Laser.";1996500;1996500;ERC-2018-COG;/ERC-COG;EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH;CH;;;;1;0;0;1;0;0 218755;822314;DISCE;SIGNED;"H2020-EU.3.6.1.1.;H2020-EU.3.6.3.1.";TRANSFORMATIONS-06-2018;H2020;Developing Inclusive & Sustainable Creative Economies;2019-01-01;2021-12-31;;"The DISCE (Developing Inclusive & Sustainable Creative Economies) project is set to improve and enhance the growth, inclusivity and sustainability of the cultural and creative industries (CCIs) in the EU. Overall, the ambitious objectives of DISCE are: i) to support the development patterns of CCIs within the EU through research on new business models and inclusive growth; and ii) to re-shape understanding of what ‘inclusive and sustainable growth’ consists of in this context, shifting the CCIs (and CCIs policy) towards strategic goals of ‘cultural development’ that encompass both GDP and human flourishing. DISCE is an interdisciplinary, mixed-methods project that builds on three pillars: 1) Robust statistical analyses, mapping and development of new statistical indices for a better understanding of the inclusive and sustainable development of CCIs in Europe; 2) In-depth case studies developing rich findings and nuanced understanding of the Creative Economies and their ecologies; and 3) Active co-creation and interaction with stakeholders to validate the policy relevance of the project, as well as the policy outcomes and achieve long-term impact and sustainability. DISCE serves all the beneficiaries relevant research results, which will help and support stakeholders to fill existing information gaps in daily policy and decision-making processes. DISCE will bring out recommendations for actors how to react, function and decide in specific situations to promote inclusive growth and progress on the sustainable development in the field of CCIs. The DISCE Consortium has six partners: University of Turku (UTU) as the Coordinator, Kings College London (KCL), Social Science Area of the Gran Sasso Science Institute (GSSI), Stockholm School of Economics in Riga (SSE) as ‘Research Partners’ and two ‘Stakeholder Partners’ Culture & Media Agency aisbl (CUMEDIAE) and Trans European Halles (TEH) both with wide networks in the field of CCIs.";2940495;2940495;H2020-SC6-TRANSFORMATIONS-2018;/RIA;TURUN YLIOPISTO;FI;"STOCKHOLM SCHOOL OF ECONOMICS IN RIGA SIA;GRAN SASSO SCIENCE INSTITUTE;TRANS EUROPE HALLES;CULTURE & MEDIA AGENCY EUROPE;KING'S COLLEGE LONDON";"LV;IT;SE;BE;UK";;1;0;0;1;0;0 220048;802217;HelixMold;SIGNED;H2020-EU.1.1.;ERC-2018-STG;H2020;Computational design of novel functions in helical proteins by deviating from ideal geometries;2019-04-01;2024-03-31;;"We propose to computationally design novel ligand binding and catalytically active proteins by harnessing the high thermodynamic stability of de novo helical proteins. Tremendous progress has been made in protein design. However, the ability to robustly introduce function into genetically encodable de novo proteins is an unsolved problem. We will follow a highly interdisciplinary computational-experimental approach to address this challenge and aim to: -Characterize to which extent we can harness the stability of parametrically designed helical bundles to introduce deviations from ideal geometry. Ensembles of idealized de novo helix bundle backbones will be generated using our established parametric design code and designed with constraints accounting for an envisioned functional site. This will be followed by detailed computational, biophysical, crystallographic and site-saturation mutagenesis analysis to isolate critical design features. -Develop a new computational design strategy, which expands on the Crick coiled-coil parametrization and allows to rationally build non-ideal helical protein backbones at specified regions in the desired structure. This will enable us to model backbones around binding/active sites. We will design sites to bind glyphosate, for which remediation is highly needed. By using non-ideal geometries and not relying on classic heptad repeating units, we will be able to access a much larger sequence to structure space than is usually available to nature, enabling us to build more specific and more stable binding/catalytically active proteins. -Investigate new strategies to design the first cascade reactions into de novo designs. This research will allow functionalization of de novo designed proteins with high thermostability, extraordinary resistance to harsh chemical environments and high tolerance for organic solvents and has the potential to revolutionize how proteins for biotechnological and biomedical applications are generated.";1499414;1499414;ERC-2018-STG;/ERC-STG;TECHNISCHE UNIVERSITAET GRAZ;AT;;;;1;0;0;1;0;0 219730;812882;PhilHumans;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2018;H2020;Personal Health Interfaces Leveraging Human-Machine Natural Interactions;2019-01-01;2022-12-31;;"The goal of the PhilHumans (Personal Health Interfaces Leveraging Human-MAchine Natural interactionS) project is to train a next generation of young researchers in innovative Artificial Intelligence (AI) and establish user interaction with their personal health devices in an advanced and intuitive way. PhilHumans will investigate cutting-edge AI methods for human-machine interaction in the personal health domain through a well-designed and structured research training programme, with the aim to enhance EU firms competitiveness in the field for an effective and lasting market penetration in EU. The research in PhilHumans will be performed by an intersectoral and multidisciplinary consortium consisting of 8 ESRs and a team of supervisors from the academic beneficiaries (University of Cagliari, University of Catania, University of Aberdeen, and Technical University of Eindhoven (TU/e)), the industrial beneficiaries (PHILIPS and R2M), and other external partners. The project will require the creation of a blend of interdisciplinary understanding of personal digital assistant, cognitive computing, (deep) machine learning, natural language generation & processing, advanced computer vision, and business development. The personal health areas that will be investigated are Mother&Child care, healthy-living and personal care, where the application of the proposed technology has promising potential. All ESRs will enroll in a 3-years PhD research programme at beneficiary academic institutions. They are supposed to act as an integrated and complementary expertize team, whose aim is to tackle the fundamental challenge of combining heterogeneous data sources from multilingual speech/text processing and computer vision for improving conversation, detecting emotions, and improving social interactions. All the academic ESRs for at least 50% of their time will attend their secondment at PHILIPS, which will provide the required infrastructure and supervision by senior research staff.";2135436,12;2135436,12;H2020-MSCA-ITN-2018;/MSCA-ITN-EID;PHILIPS ELECTRONICS NEDERLAND B.V.;NL;"THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN;UNIVERSITA DEGLI STUDI DI CATANIA;R2M SOLUTION SPAIN SL;UNIVERSITA DEGLI STUDI DI CAGLIARI;TECHNISCHE UNIVERSITEIT EINDHOVEN";"UK;IT;ES;NL";;1;0;0;1;0;0 219998;814645;MIAMi;SIGNED;H2020-EU.2.1.4.;BIOTEC-03-2018;H2020;Refactoring monoterpenoid indole alkaloid production in microbial cell factories;2019-01-01;2022-12-31;;Plants produce some of the most potent human therapeutics and have been used for millennia to treat illnesses. The monoterpenoid indole alkaloids (MIAs) are plant secondary metabolites that show a remarkable structural diversity and pharmaceutically valuable biological activities with more than 2,000 MIAs derived from the common precursor strictosidine. However, because most MIA chemicals do not have their biosynthetic pathways elucidated and MIA-producing plants are not genetically trackable, MIAs are under-represented in recently introduced medicines. In the consortium for Refactoring of Monoterpenoid Indole Alkaloids in Microbial Cell Factories (MIAMi) our main objective is to develop sustainable microbial production of new human therapies for the benefit of the European biotech industry, human health, and the environment. To do so, MIAMi will i) develop a new approach for MIA biosynthetic pathway discovery in plants founded on supervised learning algorithms based on omics data sampled from > 20 MIA producing plants, ii) contribute to standardisation of bioengineering by development of SOPs for characterisation of > 100 DNA elements for control of gene expression, protein interactions, and sub-cellular localisation, iii) build a public parts repository and Bio-CAD for forward engineering of compartmentalised biosynthetic pathway designs in yeast, and iv) apply automated genome engineering to prototype > 1,000 new-to-nature MIA biosynthetic pathway designs in order to identify robust designs for scale-up microbial MIA production processes, and evaluate the environmental benefits and risks compared to existing value chains. The excellent, interdisciplinary and inter-sectorial consortium will showcase the use of the new approaches and standardised data inventory to produce both commercially available and new-to-market MIAs rauwolscine, tabersonine and alstonine in yeast, and finally test their bioactivity as new cancer and psychosis treatment drug leads.;6648301,25;6648301,25;H2020-NMBP-BIO-2018-two-stage;/RIA;DANMARKS TEKNISKE UNIVERSITET;DK;"AXYNTIS;EXPLORA SRL;FUTURE GENOMICS TECHNOLOGIES BV;KOBENHAVNS UNIVERSITET;JOHN INNES CENTRE;UNIVERSITE DE TOURS";"FR;IT;NL;DK;UK";;1;0;0;1;0;0 219880;792494;COMPLEXDYNAMICS-PHIM;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;On the Origin of Complex Dynamics in Multi-strain Models: Insights for Public Health Intervention Measures;2019-01-01;2020-12-31;;"The dynamics of infectious diseases are by nature non-linear and the understanding of such processes is mathematically difficult, demanding concepts from various fields of mathematics tackling biological questions for real life systems. To be descriptive and predictive, models try to include relevant information on the host-pathogen-vector interactions via the available empirical data. These models have shown rich dynamic structures, with bifurcations up to chaotic attractors able to describe large fluctuations observed in real world disease incidence data. In this project, the origin of the chaotic dynamics in multi-strain epidemiological models will be studied and the mechanisms needed to generate such complex behavior will be identified in basic models, disentangling it from external forcing such as seasonality for example. Multi-strain models will be extended, in collaboration with Prof. Andrea Pugliese (Trento University) providing his experience on vector dynamics, age and space-structured epidemic modeling. The dynamics of vaccine implementation and the control of vector populations, combined with the host-pathogen interactions, will be rigorously evaluated. The over-riding aim of this project is to develop the simplest models able to address specific public health questions, taking into account the chaotic behavior found in such systems, a challenging and new approach. The developed models will be investigated using innovative methods from dynamical systems theory and stochastic processes, including an ambitious and novel application of a recently developed technique for parameter estimation in such complex systems, a method called maximum likelihood iterated filtering including dynamic noise in likelihood functions for multi-strain dynamics. This proposal requires a highly interdisciplinary approach with results applied well beyond the state-of-the-art.";180277,2;180277,2;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;UNIVERSITA DEGLI STUDI DI TRENTO;IT;;;;1;0;0;1;0;0 220131;818045;NoLiMiTs;SIGNED;H2020-EU.1.1.;ERC-2018-COG;H2020;Novel Lifesaving Magnetic Tentacles;2019-05-01;2024-04-30;;"The aim of this project is to characterize fundamental principles at the intersection of robotics, magnetics, manufacturing and medicine, which will enable intelligent tentacle-like robots to augment the capabilities of surgeons in reaching deep into the human anatomy through complex winding pathways and treat inoperable diseases. Magnetic tentacle robots, proposed here for the first time, have the potential to be thin, extremely soft and scalable, and to conform to curvilinear trajectories by leveraging magnetic control over their entire length. The surgeon needing to access difficult to reach targets such as peripheral nodules in the lungs, small diseased blood vessels and regions deep inside the brain, will be able to design personalised tentacles and fabricate them on demand. My world-leading research team in surgical robotics–to be further consolidated by this grant–will define and explore new robotic architectures, as well as the design and fabrication processes integral to this novel concept. Proprioceptive sensing, combined with mathematical models, will enable intelligent robotic control. Robotic assistance will be context dependent, ranging from joystick-based operation to autonomous control along pre-planned trajectories. An integrated design environment will help systematise and streamline implementation. The research programme consists of four work packages: 1) Robotic architectures and models; 2) Intelligence and control; 3) Rapid design, simulation and synthesis; and 4) Multi-scale experimental evaluation, embracing different scenarios where control over the entire body of the robot is crucial: lung biopsy, cardiovascular interventions and neurosurgery. This interdisciplinary research will strengthen Europe’s position in medical robotics and improve public health by reducing patient recovery times, complication rates, and treatment costs, and ultimately saving the lives of patients suffering diseases that are inoperable—and often terminal—today.";2698136;2698136;ERC-2018-COG;/ERC-COG;UNIVERSITY OF LEEDS;UK;;;;1;0;0;1;0;0 220145;803763;CLD;SIGNED;H2020-EU.1.1.;ERC-2018-STG;H2020;China, Law, and Development;2019-01-01;2023-12-31;;"The world is in the midst of a sea change in approaches to development. The rise of nationalist politics in the U.S., U.K. and Europe have questioned commitments to global governance at the same time that China has emerged as a champion of globalization, a turn of geo-political events that would have been unfathomable ten years ago. Through its own multi-lateral institutions, China is setting a new agenda for development from Europe to Oceania. China’s approach differs from Anglo/Euro/American approaches to “law and development” (LD). Whereas LD orthodoxy has sought to improve legal institutions in poor states, Chinese do not foster rule of law abroad. Instead, Chinese view law as one set of rules, among others, to facilitate economic transactions and not to foster democratization. This distinction has sparked a global debate about the so-called “China model” as an alternative to LD. Yet there is little empirical data with which to assess the means and ends of China’s expanded footprint, a question with long-term implications for much of the developing world. This project addresses that problem by proposing that even if Chinese cross-border development does not operate through transparent rules, it nonetheless has its own notion of order. The project adopts a multi-sited, mixed method, and interdisciplinary approach—at the intersection of comparative law, developmental studies, and legal anthropology—to understand the nature of China’s order. The project has two objectives: 1. To establish the conceptual bases for the study of China’s approach to law and development by developing the first systematic study of the impacts of Chinese investment on the legal systems of developing economies. 2. To experiment with a comparative research design to theorize how China’s approach suggests a type of order that extends through a conjuncture of regional and local processes and manifests itself differently in diverse contexts.";1499381;1499381;ERC-2018-STG;/ERC-STG;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;UK;;;;1;0;0;1;0;0 218811;818431;SIMBA;SIGNED;"H2020-EU.3.2.3.3.;H2020-EU.3.2.2.";LC-SFS-03-2018;H2020;Sustainable innovation of microbiome applications in food system;2018-11-01;2022-10-31;;"'As the world population is continuously increasing, the supply of food with equal accessibility has become a major issue and future challenge. Microbes are unexploited tool to increase food productivity and quality. The objective of SIMBA project is to harness complex soil and marine microbial communities (microbiomes) for the sustainable production of food. SIMBA will focus on two interconnected food chains, i.e. crop production, aquaculture. SIMBA will first launch an in silico phase in order to analyze the further pre-existing microbiome databases and earlier studies, to identify the best microbiome layout capable of supporting food chain quality and productivity. Microbiome-tailored interventions will be specifically developed including soil, plant, fish, aquaculture and food/feed processing towards optimal layout as defined in the modelling step, as follows: i) Identified optimal microbiome consortia will be designed and tested in lab, pot and field trials to improve plant productivity and health; ii) Marine microbiomes will be applied to facilitate sustainable aqua and agriculture; iii) Optimal microbe/microbe consortia will be used to convert raw-materials and residuals to high quality food, feed or finally to energy. In a final intervention step, these interactions will be monitored and tested in field, aqua-culturing, fish feeding and human studies, measuring the impact on microbiome consortia, interactions in association with factors evaluating their efficacy in terms of improving food security, productivity, quality, safety, sustainability, nutritional and health aspects. 'Near to market” microbiome applications for sustainable food systems will be provided thanks to the interdisciplinary and cross-sectional nature of the proposal and the active role of small and medium sized enterprises (SMEs).'";10530861,89;9999999,77;H2020-SFS-2018-1;/IA;LUONNONVARAKESKUS;FI;"UNIVERSITA DEGLI STUDI DI PARMA;CENTRO COLTURE SPERIMENTALI VALLE D'AOSTA SRL;HELSINGIN YLIOPISTO;AquaTT UETP Ltd;ZILT PROEFBEDRIJF BV;KOBENHAVNS UNIVERSITET;MATIS OHF;FERMBIOTICS APS;AGENZIA NAZIONALE PER LE NUOVE TECNOLOGIE, L'ENERGIA E LO SVILUPPO ECONOMICO SOSTENIBILE;BIO BASE EUROPE PILOT PLANT VZW;NECTON - COMPANHIA PORTUGUESA DE CULTURAS MARINHAS SA;NORGES MILJO-OG BIOVITENSKAPLIGE UNIVERSITET;RHEINISCHE FRIEDRICH-WILHELMS-UNIVERSITAT BONN;Fermentationexperts AS;FUNDACION CENTRO TECNOLOGICO ACUICULTURA DE ANDALUCIA;SUDAU AGRO GMBH;ALLMICROALGAE NATURAL PRODUCTS SA;NORSK INSTITUTT FOR VANNFORSKNING;WAGENINGEN UNIVERSITY;UNIVERSITAET BIELEFELD;STICHTING NEDERLANDSE WETENSCHAPPELIJK ONDERZOEK INSTITUTEN;AGRIGES SRL";"IT;FI;IE;NL;DK;IS;BE;PT;NO;DE;ES";;1;0;0;1;0;0 220126;810586;EXPLO;SIGNED;H2020-EU.1.1.;ERC-2018-SyG;H2020;Exploring the dynamics and causes of prehistoric land use change in the cradle of European farming;2019-03-01;2024-02-29;;"European societies today face unprecedented environmental change. Understanding how human societies responded to past challenges of environmental change relates to the interface between culture and environment. The EXPLO project proposes a novel interdisciplinary approach to investigate key questions regarding the interaction between past human ways of life, land use and the wider environment through a unique combination of archaeological, biological and dynamic mathematical modelling approaches. Archaeological prehistoric sites in lakes of northern Greece and the southern Balkans provide an excellent opportunity to investigate rich archives of societal and environmental change in the cradle of European farming. Natural lake sediments and submerged prehistoric settlements offer exceptional preservation conditions and uniquely holistic insights into past anthroposphere, biosphere and geosphere dynamics. More than 8,000 years ago, technological and social breakthroughs allowed the introduction of farming from western Asia to Greece and thus for the first time to Europe; however, so far there is no high-resolution picture of how this revolutionary innovation interacted with the environment, including its long-term consequences. New underwater archaeological research will allow the construction of highly precise settlement chronologies on the basis of dendrochronology, radiocarbon dating and Bayesian modelling. On-site information from excavations will be combined with off-site palaeoenvironmental data from the same lakes to investigate past adaptation strategies to the environment as well as the effects of past societies on their environments. Dynamic models integrating archaeological contexts and palaeoenvironmental data will open up the opportunity to investigate vulnerability, resilience, tipping points and thresholds of ancient agrarian economies, with implications for future food systems under a rapidly changing climate.";6403199;6403199;ERC-2018-SyG;/ERC-SyG;UNIVERSITAET BERN;CH;"ARISTOTELIO PANEPISTIMIO THESSALONIKIS - EIDIKOS LOGARIASMOS KONDILION EREVNAS;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD";"EL;UK";;1;0;0;1;0;0 218631;824074;GrowBot;SIGNED;H2020-EU.1.2.2.;FETPROACT-01-2018;H2020;Towards a new generation of plant-inspired growing artefacts;2019-01-01;2022-12-31;;"GrowBot proposes a disruptively new paradigm of movement in robotics inspired by the moving-by-growing abilities of climbing plants. Plants are still a quite unexplored model in robotics and ICT technologies, as their sessile nature leads to think that they do not move. Instead, they move greatly, on a different time scale, purposively, effectively and efficiently. To move from one point to another, plants must grow and continuously adapt their body to the external environmental conditions. This continuous growth is particularly evident in climbing plants. By imitating them, the GrowBot objective is to develop low-mass and low-volume robots capable of anchoring themselves, negotiating voids, and more generally climbing, where current climbing robots based on wheels, legs, or rails would get stuck or fall. Specifically, the ability to grow will be translated by additive manufacturing processes inside the robot, which creates its body by depositing new materials with multi-functional properties, on the basis of the perceived external stimuli (without a pre-defined design). Energy efficiency will be intrinsic to such approach, but novel bio-hybrid energy harvesting solutions will be also implemented to generate energy by interfacing soft technologies with real plants. Perception and behavior will be based on the adaptive strategies that allow climbing plants to explore the environment, described mathematically after experimental observations. GrowBot would contribute to consolidate this ground-breaking and pioneering research area on plant-inspired robotics that, although still in its infancy, can represent a revolutionary approach in robotics, as it has already happened with plant-inspired solutions in material science. GrowBot is based on a strongly interdisciplinary character and can open the way for a new technological paradigm around the concept of growing robots, fostering a European innovation eco-system for several high-tech sectors.";6997482,5;6997482,5;H2020-FETPROACT-2018-01;/RIA;FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA;IT;"ARKYNE TECHNOLOGIES SL;ALBERT-LUDWIGS-UNIVERSITAET FREIBURG;LINARI ENGINEERING SRL;HELMHOLTZ-ZENTRUM GEESTHACHT ZENTRUM FUR MATERIAL- UND KUSTENFORSCHUNG GMBH;SCUOLA SUPERIORE DI STUDI UNIVERSITARI E DI PERFEZIONAMENTO SANT'ANNA;GRAN SASSO SCIENCE INSTITUTE;TEL AVIV UNIVERSITY;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS";"ES;DE;IT;IL;FR";;1;0;0;1;0;0 219907;815379;AutoCAb;SIGNED;H2020-EU.1.1.;ERC-2018-COG;H2020;Automated computational design of site-targeted repertoires of camelid antibodies;2019-01-01;2023-12-31;;"We propose to develop the first high-throughput strategy to design, synthesize, and screen repertoires comprising millions of single-domain camelid antibodies (VHH) that target desired protein surfaces. Each VHH will be individually designed for high stability and target-site affinity. We will leverage recent methods developed by our lab for designing stable, specific, and accurate backbones at interfaces, the advent of massive and affordable custom-DNA oligo synthesis, and machine learning methods to accomplish the following aims: Aim 1: Establish a completely automated computational pipeline that uses Rosetta to design millions of VHHs targeting desired protein surfaces. The variable regions in each design will be encoded in DNA oligo pools, which will be assembled to generate the entire site-targeted repertoire. We will then use high-throughput binding screens followed by deep sequencing to characterize the designs’ target-site affinity and isolate high-affinity binders. Aim 2: Develop an epitope-focusing strategy that designs several variants of a target antigen, each of which encodes dozens of radical surface mutations outside the target site to disrupt potential off-target site binding. The designs will be used to isolate site-targeting binders from repertoires of Aim 1. Each high-throughput screen will provide unprecedented experimental data on target-site affinity in millions of individually designed VHHs. Aim 3: Use machine learning methods to infer combinations of molecular features that distinguish high-affinity binders from non binders. These will be encoded in subsequent designed repertoires, leading to a continuous “learning loop” of methods for high-affinity, site-targeted binding. AutoCAb’s interdisciplinary strategy will thus lead to deeper understanding of and new general methods for designing stable, high-affinity, site-targeted antibodies, potentially revolutionizing binder and inhibitor discovery in basic and applied biomedical research.";2337500;2337500;ERC-2018-COG;/ERC-COG;WEIZMANN INSTITUTE OF SCIENCE;IL;;;;1;0;0;1;0;0 220272;824115;HiDALGO;SIGNED;H2020-EU.1.4.1.3.;INFRAEDI-02-2018;H2020;HPC and Big Data Technologies for Global Systems;2018-12-01;2021-11-30;;Developing evidence and understanding concerning Global Challenges and their underlying parameters is rapidly becoming a vital challenge for modern societies. Various examples, such as health care, the transition of green technologies or the evolution of the global climate up to hazards and stress tests for the financial sector demonstrate the complexity of the involved systems and underpin their interdisciplinary as well as their globality. This becomes even more obvious if coupled systems are considered: problem statements and their corresponding parameters are dependent on each other, which results in interconnected simulations with a tremendous overall complexity. Although the process for bringing together the different communities has already started within the Centre of Excellence for Global Systems Science (CoeGSS), the importance of assisted decision making by addressing global, multi-dimensional problems is more important than ever. Global decisions with their dependencies cannot be based on incomplete problem assessments or gut feelings anymore, since impacts cannot be foreseen without an accurate problem representation and its systemic evolution. Therefore, HiDALGO bridges that shortcoming by enabling highly accurate simulations, data analytics and data visualisation but also by providing knowledge on how to integrate the various workflows and the corresponding data.;7991500;7991500;H2020-INFRAEDI-2018-1;/RIA;ATOS SPAIN SA;ES;"MOONSTAR COMMUNICATIONS GMBH;INSTYTUT CHEMII BIOORGANICZNEJ POLSKIEJ AKADEMII NAUK;PARIS-LODRON-UNIVERSITAT SALZBURG;DIALOGIK GEMEINNUETZIGE GESELLSCHAFT FUER KOMMUNIKATIONS- UND KOOPERATIONSFORSCHUNG mbH;ARH INFORMATIKAI ZARTKORUEN MUKODO RESZVENYTARSASAG;MAGYAR KOZUT NONPROFIT ZARTKORUEN MUKODO RESZVENYTARSASAG;SZECHENYI ISTVAN UNIVERSITY;EUROPEAN CENTRE FOR MEDIUM-RANGE WEATHER FORECASTS;BRUNEL UNIVERSITY LONDON;UNIVERSITAET STUTTGART;INSTITUTE OF COMMUNICATION AND COMPUTER SYSTEMS;KNOW-CENTER GMBH RESEARCH CENTER FOR DATA-DRIVEN BUSINESS & BIG DATA ANALYTICS";"DE;PL;AT;HU;UK;EL";;1;0;0;1;0;0 219882;803370;CRACK;SIGNED;H2020-EU.1.1.;ERC-2018-STG;H2020;Cracking the neural code of human object vision;2019-05-01;2024-04-30;;At each blink of our eyes, our brain rapidly transforms the stream of photons hitting the retina into a conscious percept of the world as consisting of meaningful objects that guide our actions to ensure survival. Yet, in spite of intense research three interrelated, fundamental, long-standing and open questions about how neural dynamics mediate object recognition remain unanswered: How exactly do the core cortical regions active during vision represent objects? How and what do those regions communicate? How does the observed activity mediate adaptive behavior? The overall goal of the program CRACK is to crack the neural code of object vision by addressing those three fundamental questions. For this, CRACK will integrate in an unprecedented manner cutting-edge, non-invasive brain imaging methods, advanced multivariate analysis techniques and state-of-the-art computational modelling in an ambitious three-step interdisciplinary work program. Each step is marked by innovation that breaks new ground and opens new horizons at the next step. First, CRACK will unravel the unique representational format of each core cortical region using an unprecedented brain mapping approach that combines brain imaging with artificial deep neural networks (DNNs). Second, it will clarify the flow of information between visual regions that creates these representations with unseen spatiotemporal precision by resolving neural activity in both cortical layers and frequency channels using a combination of functional MRI (fMRI) and electroencephalography (EEG). Third, it will use advanced multivariate methods linking brain activity and behavior to reveal which aspects of the newly described neural dynamics drive human choice behavior. By breaking down current knowledge boundaries, CRACK will provide the empirical evidence for a new theory of the neural dynamics underlying human visual object recognition, and transform the way we think about and investigate sensory processing.;1480576;1480576;ERC-2018-STG;/ERC-STG;FREIE UNIVERSITAET BERLIN;DE;;;;1;0;0;1;0;0 220277;804468;EAGER;SIGNED;H2020-EU.1.1.;ERC-2018-STG;H2020;Elucidating the effects of ageing on the nucleoporin-directed neural cell type-specific nuclear architecture and gene regulation;2019-03-01;2024-02-29;;"Ageing is one of the most critical risk factors for neurological and psychiatric diseases. However, the biological links between physiological ageing and pathological development are still largely unknown. A solid understanding of the biology of brain ageing will thus be a key to developing the means to treat these diseases. Since neurons in the brain are mostly generated during development with limited capacity of replacement after birth, they need to maintain their identity and function throughout our lives. This project aims at seeking a link between the fundamental mechanism underlying the long-term maintenance of neural identity and effects of ageing on that. We recently discovered that a cell type-specific nuclear architecture organized by nucleoporins in cooperation with a key transcription factor (TF), work as a structural gatekeeper for the maintenance of neural progenitor cells (NPs). Strikingly, nucleoporins are the most long-lived proteins in a cell and are known to be damaged during brain ageing. Thus, the proposed experiments will test a specific hypothesis that the nucleoporin-TF directed nuclear architecture is a fundamental principle governing cell type-specific gene regulation, and that pathological ageing impairs that critical relationship. To test this hypothesis, we will use interdisciplinary approaches. First, the changes of molecular constituents of nucleoporin-TF partnerships from NPs into the post-mitotic neurons are probed. Second, the roles of identified partnerships in the maintenance of neuronal identity and function will be investigated using biochemical, imaging, genome-wide and behavioural approaches. Efforts will be directed toward studying the effects of ageing and Alzheimer’s diseases on the identified mechanisms. The successful completion of this research will uncover a novel aspect of regulation in the maintenance of cellular identity and open up a new field of research in neuroscience.";1499998,75;1499998,75;ERC-2018-STG;/ERC-STG;DEUTSCHES ZENTRUM FUR NEURODEGENERATIVE ERKRANKUNGEN EV;DE;;;;1;0;0;1;0;0 220225;826078;FeatureCloud;SIGNED;H2020-EU.3.1.5.1.;SU-TDS-02-2018;H2020;Privacy preserving federated machine learning and blockchaining for reduced cyber risks in a world of distributed healthcare;2019-01-01;2023-12-31;;The digital revolution, in particular big data and artificial intelligence (AI), offer new opportunities to transform healthcare. However, it also harbors risks to the safety of sensitive clinical data stored in critical healthcare ICT infrastructure. In particular data exchange over the internet is perceived insurmountable posing a roadblock hampering big data based medical innovations. FeatureCloud’s transformative security-by-design concept will minimize the cyber-crime potential and enable first secure cross-border collaborative data mining endeavors. FeatureCloud will be implemented into a software toolkit for substantially reducing cyber risks to healthcare infrastructure by employing the world-wide first privacy-by-architecture approach, which has two key characteristics: (1) no sensitive data is communicated through any communication channels, and (2) data is not stored in one central point of attack. Federated machine learning (for privacy-preserving data mining) integrated with blockchain technology (for immutability and management of patient rights) will safely apply next-generation AI technology for medical purposes. Importantly, patients will be given effective means of revoking previously given consent at any time. Our ground-breaking new cloud-AI infrastructure only exchanges learned model representations which are anonymous by default. Collectively, our highly interdisciplinary consortium from IT to medicine covers all aspects of the value chain: assessment of cyber risks, legal considerations and international policies, development of federated AI technology coupled to blockchaining, app store and user interface design, implementation as certifiable prognostic medical devices, evaluation and translation into clinical practice, commercial exploitation, as well as dissemination and patient trust maximization. FeatureCloud’s goals are bold, necessary, achievable, and paving the way for a socially agreeable big data era of the Medicine 4.0 age.;4646000;4646000;H2020-SC1-FA-DTS-2018-1;/RIA;TECHNISCHE UNIVERSITAET MUENCHEN;DE;"PHILIPPS UNIVERSITAET MARBURG;MEDIZINISCHE UNIVERSITAT GRAZ;GNOME DESIGN SRL;UNIVERSITEIT MAASTRICHT;SYDDANSK UNIVERSITET;SBA RESEARCH GEMEINNUTZIGE GMBH;Concentris Research Management GmbH;RESEARCH INSTITUTE AG & CO KG";"DE;AT;RO;NL;DK";;1;0;0;1;0;0 220025;826161;WASTE2GRIDS;SIGNED;H2020-EU.3.3.8.2.;FCH-02-8-2018;H2020;Converting WASTE to offer flexible GRID balancing Services with highly-integrated, efficient solid-oxide plants;2019-01-01;2020-06-30;;The overall objective of the Waste2GridS (W2G) project is to identify the most promising industrial pathways of waste gasification and solid-oxide cell (SOC) integrated power-balancing plants (W2G plants in short). The project aims are to perform a preliminary investigation on the long-term techno-economic feasibility of W2G plants to meet different grid-balancing needs and to identify several promising business cases with necessary preconditions. To achieve such goals, an interdisciplinary team is formed by gathering leading research bodies and companies in Europe in the fields of solid-oxide reversible cells (SORC), waste identification, gasification and syngas cleaning, grid operation, and energy/process systems engineering. The results of the project will further enhance the knowledge exchange and interaction among different key players (manufacturers, investors, and research institutions), provide useful guidelines for technology development/deployment and market positioning, increase long-term competitiveness and leadership of relevant industries, and provide knowledge for policy support on W2G plants for a circular economy and for the decarbonisation of European energy systems.;528750;528750;H2020-JTI-FCH-2018-1;/FCH2-RIA;ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE;CH;"AGENZIA NAZIONALE PER LE NUOVE TECNOLOGIE, L'ENERGIA E LO SVILUPPO ECONOMICO SOSTENIBILE;DANMARKS TEKNISKE UNIVERSITET;SOLIDPOWER SA";"IT;DK;CH";;1;0;0;1;0;0 219553;801459;FP-RESOMUS;SIGNED;H2020-EU.1.3.4.;MSCA-COFUND-2017;H2020;Fellowship Program of the NCCR MUST (National Competence Center for Research in MolecularUltrafast Science and Technology) and the Cluster of Excellence RESOLV;2019-04-01;2023-09-30;;"The Swiss research network NCCR MUST (National Center of Competence in Research Molecular Ultrafast Science and Technology) and the German Cluster of Excellence RESOLV (Ruhr Explores Solvation) propose to establish the new Postdoctoral Fellowship Program FP-RESOMUS. FP-RESOMUS will be integrated in and fed by the two national networks of research teams, bringing together over 70 research groups covering the fields of chemistry, physics, material sciences, engineering, and biology to solve interdisciplinary scientific questions using the latest available technology and theoretical insights. Both RESOLV and the NCCR MUST operate at the frontiers of what is technically possible, in large parts complementary in focussing on fundamental and applied research on ultrafast processes and solvation. Building on the existing cooperation between the two networks, the FP-RESOMUS is well placed to attract postdoctoral fellows from all around the world (incoming), further promote the exchange of postdoctoral researchers between the two networks (outgoing) as well as enabling the return of Swiss and German researchers who have worked overseas into a European research environment (reintegration). It is our vision that novel technologies, advanced modeling techniques, and the spirit of our thriving networks create an ideal environment for high-level postdoctoral research projects. Our program will provide Europe with a new generation of researchers in ultrafast and solvation sciences and therefore considerably improve the research quality of the ERA.";7080000;3540000;H2020-MSCA-COFUND-2017;/MSCA-COFUND-FP;EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH;CH;;;;1;0;0;1;0;0 217979;813528;PET-AlphaSy;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2018;H2020;PET Imaging of Alpha-Synuclein Fibril Formation;2018-09-01;2022-08-31;;Too often, physicians have to rely on a trial and error strategy until the most effective treatment for an individual patient is identified. This leads to a critical loss of time, making the healthcare system ineffective and expensive. In respect to drug development, a high failure rate is apparent at all stages of development and ways to reduce this have high priority for the pharmaceutical industry. To this end, drug development and medicinal treatment need to be more personalized and molecular imaging techniques, in particular Positron Emission Tomography (PET) imaging, can be used to achieve this by 1) evaluating the effectiveness of new treatments emerging from the pharmaceutical industry, 2) improving the ability to diagnose diseases, and 3) aid tailoring the treatment based on individual patient pathology. A limiting factor to develop new effective PET imaging probes is the insufficient number of radiopharmaceutical scientists presently available. Our consortium has assembled 6 radiopharmaceutical frontline academic and 10 non-academic partners to address this problem and train the next generation of radiopharmaceutical scientists. Our training will be focused on an unmet scientific need for Parkinson’s Disease (PD). Fibril formation of protein ?-synuclein is thought to be the hallmark for PD, but presently, there are no validated PET tracers available for visualization of pathogenic aggregates of this protein. Our scientific goal is to develop such tracer. A successful tracer will have a strong impact on PD-diagnosis and facilitate the development of effective disease modifying treatments. To reach our goals, it is necessary to train our early stage researchers in a highly interdisciplinary fashion spanning from chemistry, over biology, GMP and pharmacy to nuclear medicine. Furthermore, this consortium will train entrepreneurial skills and facilitate start up new enterprises in the current favorable radioisotope market situation.;4100370,12;4100370,12;H2020-MSCA-ITN-2018;/MSCA-ITN-ETN;KOBENHAVNS UNIVERSITET;DK;"REGION HOVEDSTADEN;JOHANNES GUTENBERG-UNIVERSITAT MAINZ;UPPSALA UNIVERSITET;STICHTING VUMC;EBERHARD KARLS UNIVERSITAET TUEBINGEN;ELYSIA;BIOARCTIC AB";"DK;DE;SE;NL;BE";;1;0;0;1;0;0 207460;734759;VAHVISTUS;SIGNED;H2020-EU.1.3.3.;MSCA-RISE-2016;H2020;Integrative development of smart drug-vector nanostructures for adaptive delivery to target cells;2017-03-01;2021-02-28;;The proposal is devoted to a development of smart drug-vector nanostructures (DVNs) based on stimuli-responsive inorganic, hybrid inorgano-organic nanomatrices, and polymer nanocapsules bearing new pharmaceutically active compounds (PhACs) and synthetic derivatives of natural PhACs. The innovative idea is the DVNs can enter target cancer cell or protozoan parasite infected cell through receptor mediated endocytosis and interact with distinct compartments of the cellular secretory pathway. Owing to adaptive drug release in response to variations in pH and redox environment, the parasite growth or cancer cells proliferation will be suppressed. For this purpose, strongly international and interdisciplinary VAHVISTUS consortium is created. Thus, principal objective of the proposal is to strengthen the existing international collaborations between the Consortium Partners and to establish new long-lasting international and inter-sectoral ones, to provide knowledge sharing through exchanges of research and innovation staff, and to create an intercontinental network in the area of smart DVNs for adaptive delivery to target cells. 6 academic organisations and 1 industrial partner of the Consortium from 3 MS/AC and 3 TC will develop intense and continuous knowledge sharing by cross-fertilisation of ideas through international and intersectoral secondments of staff at different carrier stages. The exchanges are well balanced between ER and ESR, men and women. The Proposal implementation is divided into 7 Work packages. A multicultural creative environment within the VAHVISTUS will contribute to make research and innovation an attractive carrier. Communication and dissemination activities as well as exploitation of results will be crucial within the VAHVISTUS. The Project results will enhance the competitiveness of European pharmaceutical industry, health care, and higher education. A Summer school will be organised on Smart Nanocarriers for Adaptive Drug Delivery.;1084500;990000;H2020-MSCA-RISE-2016;/MSCA-RISE;HELSINGIN YLIOPISTO;FI;"JOINT STOCK COMPANY FARMAK;INSTITUTE OF ORGANIC CHEMISTRY OF NATIONAL ACADEMY SCIENCES OF UKRAINE;CONSIGLIO NAZIONALE DELLE RICERCHE";"UA;IT";;1;0;0;1;0;0 195316;656748;KEME;CLOSED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Knitting early modern Europe: materials, manufacture and meaning;2015-08-01;2017-07-31;;The development of knitting was a key technological innovation for which there is little published scientific evidence. There are more than 100 knitted caps from the early modern era in museum collections worldwide - an astonishing number given the paucity of extant garments from the period. Despite their diverse locations, they have remarkable similarities in their materials and manufacture which illustrate trade in knitted caps as consumer goods in the emerging early modern European marketplace, demonstrate how knitting created new fashions for men indicative of rank and status, and facilitate theory on the cultural significance of the hat as an essential male accessory. My preliminary study of the caps tracks clear patterns in the data: five typologies are identifiable and when contextualised with pictorial and documentary sources, their cultural significance as functional and fashionable men’s wear is clear. I believe the caps’ potential as indicators of the development and growth of knitting technology is valuable yet vulnerable. The caps are fragile and deteriorating, a process accelerated by each viewing, for which there is pressing and unsatisfied demand. I propose immediate rigorous scientific study (radiocarbon dating, microscopic examination, x-radiography, fibre and dye identification, and degradation analysis) and interdisciplinary research into contemporary sources to chart an economic map of early knitting, to define terminology for further scholarly work, and to develop theory about men’s headwear in the 16th century. An online database will make the data accessible to scholars, museum pedagogues and craftspeople, who demand access to the caps. Journal articles, practical workshops and social media will disseminate my conclusions and my development of theory. I will give voice to an eloquent body of evidence about early modern knitting technology, which threatens to be silenced forever if scientific analysis is delayed.;212194,8;212194,8;H2020-MSCA-IF-2014;/MSCA-IF-EF-CAR;KOBENHAVNS UNIVERSITET;DK;;;;1;0;0;1;0;0 195607;658442;MINOTAUR;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Metabolic interactions in oceanic photosymbioses;2016-01-01;2017-12-31;;Symbiosis between heterotrophic hosts and microalgae (photosymbiosis) is a widespread and ecologically important phenomenon in the oceanic plankton. Symbiotic organisms like radiolarians (unicellular eukaryotes) are key players in marine biogeochemical cycles by contributing to predation and primary production. While knowledge of the diversity of symbiotic partners has improved in recent years, metabolic interactions remain poorly understood. This project will explore the metabolic basis of planktonic photosymbiosis, with radiolarians as an ecologically relevant model, to understand the functioning of the partnership and its contribution to elemental cycling in the pelagic ecosystem. An original and cutting-edge single-cell approach involving stable isotopes and high-resolution chemical imaging techniques (e.g. ToF-SIMS and nanoSIMS) will be used to visualize the elemental and isotopic composition of intact radiolarian symbioses at the subcellular level, and to quantify the assimilation and transfer of nutrients between partners in different experimental conditions. The same approach will be applied on cultured free-living symbionts to determine the degree of host control over symbiont metabolism. In order to develop a holistic view of metabolic interactions, bioinformatic analyses will identify key metabolic genes and pathways from available transcriptomes of radiolarians. The exceptional microscopy facility and expertise in isotope biogeochemistry at the host institution is unique in Europe. Given the interdisciplinary nature of the project consortium, the potential for exchanging new knowledge and skills is very high. This project pushes back the boundaries of marine biological research and represents a significant step in my personal development towards my long-term research ambition to merge knowledge on biodiversity and physiology into ecological studies to better understand the functioning of aquatic ecosystems and their responses to anthropogenic pressures.;171460,8;171460,8;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;HELMHOLTZ-ZENTRUM FUR UMWELTFORSCHUNG GMBH - UFZ;DE;;;;1;0;0;1;0;0 195200;656000;BeSec;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Beyond the Secular: Narrativizing religious change in contemporary German novels;2016-03-01;2018-02-28;;The death of God and the disenchantment of the world are central to self-presentations of modernity. At the dawn of the third millennium, however, the worldwide growth of religious fundamentalisms as well as the pluralisation and individualization (but not the disappearance) of faith in the West suggest the need for a more nuanced understanding of the relation between secularity, modernity and religion. This is not only a matter for empirical research in Social, Political and Religious Studies. “Modernity,” “secularity” and “religion” are, in important ways, interpretive categories shaped by cultural narratives through which individuals and societies understand their world. The project “Beyond the Secular” studies a defined corpus of such narratives: contemporary German-language novels which articulate non-secular and religious experiences and worldviews. Through an interdisciplinary methodology combining close reading and narratological analysis with contextual readings in religious sociology, theology, and political philosophy, the project seeks to determine the potential of literature for the perception and narrativization of religious change in late modern societies.;195454,8;195454,8;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;THE UNIVERSITY OF WARWICK;UK;;;;1;0;0;1;0;0 193907;642380;MET-A-FOR;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2014-EID;H2020;Metabolomic analysis for the forensic detection of drugs of abuse in performance and food producing animals;2015-01-01;2018-12-31;;Forensic detection of the illicit use of drugs in performance and food-producing animals is experiencing critical shifts in paradigms with a growing threat in the form of new compounds emerging from human drug development and clinical applications. The MET-A-FOR project will be the first European training platform solely focussed on the development and practical advancement of animal forensic testing based on new concepts in metabolomics. This EID programme will train 3 early stage researchers (ESRs) to be creative, problem-solving and entrepreneurial European scientists with skills in high level interdisciplinary and intersectoral analytical techniques who can aid the translation of emerging discoveries from the academic sector to the commercial sector. The MET-A-FOR project will through the training and development of ESR Fellows and their completion of defined interconnecting PhD projects, bridge the knowledge gaps surrounding the novel concept of metabolomic profiling evident between fundamental researchers in academia (QUB) who have been developing such methods, and non-academic commercial end-users (IDLS) who recognise the necessity and opportunity to apply these methods as diagnostic services. The training of researchers who can utilise these novel innovative analytical tools to increase analysis speeds and sample screening throughput will be essential for providing continuing confidence in monitoring controls and regulations and maintaining animal welfare standards within Europe. ESR Fellows graduating from the MET-A-FOR programme will be uniquely situated to lead, innovate, and collaborate on future technological innovation in the field of analytical monitoring and forensic testing of performance and food producing animals as the challenges in this area increase.;819863,64;819863,64;H2020-MSCA-ITN-2014;/MSCA-ITN-EID;THE QUEEN'S UNIVERSITY OF BELFAST;UK;Irish Diagnostic Laboratory Services Limited;IE;;1;0;0;1;0;0 219574;805074;VOLARE;SIGNED;H2020-EU.1.1.;ERC-2018-STG;H2020;Scentsitive nature: Green leaf volatile perception in plants and insects;2019-02-01;2024-01-31;;"Plant leaves can emit large amounts of volatiles into the air. When attacked by insects, the composition of these blends changes markedly. It is well known that these changes affect not only the behavior of insects interacting with the plant but also the metabolism of the plant itself as well as its nearby competitors. However, how plants perceive these volatiles and generate a functional response is not known. My research activities have been dedicated to a group of plant volatiles emitted the earliest upon herbivory, the so-called green leaf volatiles (GLVs). I discovered a class of enzymes, present in plants and insects, that profoundly affect ecological interactions by converting the highly abundant GLV Z-3-hexenal into E-2-hexenal (Science 2010, eLife 2013, Frontiers in Plant Science 2017). These two compounds, as well as their derivatives, among which Z-3- and E-2-hexenyl acetate, have distinct effects on the behavior of herbivorous and predacious insects as well as on the metabolism of plants. Here I propose to take my program to the next level by elucidating how plants and insects perceive E-2-hexenal and hexenyl acetates. First I will use a classical mutagenesis screen and a cutting-edge technique called chemical yeast 3-hybrid (Y3H) to identify plant proteins involved in signal processing and especially perception of volatiles. With the newly identified genes in hand I will create non-responsive mutant plants to investigate the role of these key volatiles in the plant's self-recognition and its interactions with herbivorous insects and pathogens. Simultaneously, I will use Y3H to also identify insect proteins that directly interact with either E-2-hexenal or E-2-hexenyl acetate and I will create non-responsive insects using CRISPR-Cas9 and assess how this affects their behavior. This interdisciplinary research project will uncover the perception mechanism of key plant volatile signals and the roles these play in the (eco)physiology of plants and insects.";1500000;1500000;ERC-2018-STG;/ERC-STG;UNIVERSITEIT VAN AMSTERDAM;NL;;;;1;0;0;1;0;0 193857;641858;PREDICTABLE;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2014-ETN;H2020;Understanding and predicting developmental language abilities anddisorders in multilingual Europe;2015-03-01;2019-04-30;;PredictAble aims to train a new generation of young scientists at the crossroads between academic research, technological development in the private sector and clinical practice to pioneer an interdisciplinary approach to language related developmental disorders, like specific language impairment (SLI) and developmental dyslexia (DD). The innovative and timely research program will enhance the understanding of the cognitive mechanisms that underlie developmental disorders of spoken and written language by pooling international experts from academia and the private sector. For the first time, PredictAble applies a truly multidisciplinary and cross-linguistic perspective with a unique and novel combination of cutting-edge approaches and techniques for studying mono- and bilingual children. Thus, PredictAble will provide young researchers with an excellent foundation for making scientific progress in this area, in collaboration with technology development and the transfer of research outcomes to applicants in the private sector and the health sector/clinical practice. Highly recognized experts in the area of language acquisition in very young mono- and bilingual children will work together on the acquisition of spoken and written language in a cross-linguistic approach. The complementarity of the different languages in PredictAble will make it possible to identify language-specific and cross-linguistically valid effects. In cooperation with technological partners from the private sector, PredictAble will optimize recently developed technologies in the area of developmental cognitive neuroscience to render them suitable for use with very young children and as diagnostic tools to detect early risks for language-related impairments.;3848639,76;3848639,76;H2020-MSCA-ITN-2014;/MSCA-ITN-ETN;UNIVERSITAET POTSDAM;DE;"UNIVERSIDAD POMPEU FABRA;JYVASKYLAN YLIOPISTO;NIRX MEDIZINTECHNIK GMBH;UNIVERSITE PARIS DESCARTES";"ES;FI;DE;FR";;1;0;0;1;0;0 193430;636865;SteamBio;SIGNED;H2020-EU.2.1.5.3.;SPIRE-02-2014;H2020;Flexible Superheated Steam Torrefaction and Grinding of Indigenous Biomass from Remote Rural Sources to Produce Stable Densified Feedstocks for Chemical and Energy Applications;2015-02-01;2018-07-31;;'The objective of SteamBio is to demonstrate a mobile processing concept that will enable efficient pre-treatment of agro-forestry residues for use as flexible feedstocks in chemical and process industries. These ligno-cellulosic materials originated from rural locations will be upgraded and densified into uniform sizes at source, allowing cost-effective transportation to existing industrial sites. The core enabling technology is superheated steam processing (SHS). SHS has been implemented in diverse drying applications at industrial scales, due to its superior heat transfer properties. At pilot scales, SHS has been proven to torrefy biomass at temperatures up to 300°C with minimal ligno-cellulose breakdown. Unlike conventional torrefaction techniques, which use flue gases as heating medium, it does not contaminate the torrefied biomass and volatile fractions, allowing economic recovery of chemicals. Moreover, it is also readily scalable for continuous operation. In SteamBio, a transportable demonstrator unit will be operated at five different rural locations where it will be used to torrefy tonnage quantities of six different agro-forestry residues at a throughput of 500 kg/h. The demonstrator unit will be operated at these rural locations throughout the last twelve months of the project to allow for seasonal fluctuations in the composition of the materials being valorised. The torrefied biomass fractions (solid and liberated volatiles) will then be validated as green building blocks in commercially relevant chemical production and in bioenergy use. Life cycle experts will validate that SteamBio will have positive environmental impacts. A robust business strategy will be developed to enable the results to cross the 'valley of death' post-project and to ensure widespread market replication. Project delivery will be achieved by an interdisciplinary team from research and from the entire industrial and commercial supply chain from fields through to factories.';6979982,05;5829783,42;H2020-SPIRE-2014;/IA;FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.;DE;"FUNDACION CIRCE CENTRO DE INVESTIGACION DE RECURSOS Y CONSUMOS ENERGETICOS;HTCycle GMBH;NETWORK NEW EUROPE LIMITED;KREW ENVIROMENTAL LTD;SVERIGES LANTBRUKSUNIVERSITET;COMERCIAL E INDUSTRIAL ARIES SA;MANROCHEM LIMITED;NORMAG LABOR- UND PROZESSTECHNIK GMBH;URBION CONSULTORES SL;HECKMANN METALL- UND MASCHINENBAU GMBH;UNIVERSITY OF STRATHCLYDE";"ES;DE;UK;SE";;1;0;0;1;0;0 205749;705225;MEDICINE;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-GF;H2020;MEDICINE. Indigenous concepts of health and healing in Andean populations: understanding the relevance of traditional MEDICINE in a changing world.;2016-11-01;2019-10-31;;"In the context of a complex global agenda in traditional and complementary medicine, indigenous concepts of health and healing are less well documented and understood. MEDICINE will examine concepts of health and healing from an indigenous and culturally specific context, taking a unique time-depth perspective and with a framework of interdisciplinary methods which integrates archaeological-historical, ethnographic and modern health sciences approaches. MEDICINE offers a novel perspective and methods in the development policies sensitive to indigenous and minority people’s social, economic and health needs and, too, on developing culturally sensitive approaches to the conservation of their ‘intangible cultural heritage’. MEDICINE will also develop novel methodological and theoretical approaches to model how peoples survive and adapt their traditional belief systems in a context of alien cultural impacts. The study population are indigenous Quichua peoples in the northern Andean region of Ecuador, a country where the ER has considerable experience. Models of their understanding of health, illness and healing, and the way these have adapted and changed through time will be used to develop a ‘tool’ transferable to contemporary global policy scenarios. MEDICINE will benefit from the ER's unique perspectives from Medicine and Archaeology to explore the impact of traumatic cultural transition on people, the significance of traditional practices as intangible cultural heritage, and the degree to which the longer-term archaeological perspective can help promote understanding in a vital area of contemporary concern. It will enable her to develop further policy relevant skills, a particular output being contributions to policy and practice in the development of culturally sensitive approaches to the health and social needs of migrant and minority peoples from traditional cultural backgrounds.";217708,2;217708,2;H2020-MSCA-IF-2015;/MSCA-IF-GF;UNIVERSITY OF YORK;UK;;;;1;0;0;1;0;0 220406;802990;PROFECI;SIGNED;H2020-EU.1.1.;ERC-2018-STG;H2020;Mediating the Future: The Social Dynamics of Public Projections;2019-02-01;2024-01-31;;"People’s lives, both as individuals and at the collective level, are guided by projections about the future. This project aims to understand the complex processes through which projections about political issues, such as the outcomes and implications of elections, referenda, crises or wars, are formulated and negotiated within and through the media. It develops a new interdisciplinary approach and research tools for studying how projections evolve over time and through the contribution of various social actors (such as politicians, experts and journalists), and how they are received and acted upon by the public. The focus is on at least three retrospective case studies (projections about the Brexit referendum; the civil war in Syria; and Donald Trump's presidential bid) as well as three real-time case studies (to be selected based on geopolitical developments), characterised by high-visibility and involving projections with far-reaching implications. PROFECI integrates cutting-edge qualitative, quantitative and automated approaches to capture the interactive process underlying the construction and evolution of public projections, and their reciprocal relationship with people’s expectations and behaviour. It begins with an in-depth investigation of the construction, transformation and reception of projections made by key actors, using textual analysis of the source projections and their journalistic coverage, reconstruction interviews with experts and journalists, and focus groups with public members. The results of this stage inform the development of tools for a large-scale diachronic automated text analysis and panel surveys, which will be applied to the real-time and the retrospective case studies. By elucidating the life cycle of projections in a mediated environment, PROFECI opens up new avenues for understanding and researching adaptive social processes, such as self-fulfilling and self-defeating prophecies, and the role of the media in shaping the future.";1499732;1499732;ERC-2018-STG;/ERC-STG;THE HEBREW UNIVERSITY OF JERUSALEM;IL;;;;1;0;0;1;0;0 220401;802244;POAB;SIGNED;H2020-EU.1.1.;ERC-2018-STG;H2020;The Psychology of Administrative Burden;2019-02-01;2024-01-31;;"The burdens of dealing with administrative rules and red tape in government are a fact of life around the world, ranging from small hassles to heavy burdens in the form of stigmatizing processes of proving eligibility and facing potential sanctions. In light of the immense importance of such burdens for millions of people and for the effectiveness of benefit programs, we know surprisingly little about the conditions that give rise to experiences of burden. POAB combines and extends extant theory and uses a unique combination of experimental methods and data to explain how, why, and for whom administrative rules are experienced as burdensome. POAB studies comprehensive rules regarding unemployment and social benefits and will provide novel register, physiological, and survey measures of welfare benefit recipients’ experiences of burden. I develop and test three theories to explain differences in experiences of burden: 1) How resource scarcity causes cognitive load and hence reduces the ability to cope with rules; 2) How self-efficacy increases the ability to cope with rules; and 3) How perceptions of being undeserving cause stigma and stress. POAB analyses the causal impact of rules on burden. To this end, I use a unique combination of complementary experimental methods in political science: 1) Cross-national lab experiments with physiological measurement and manipulations of rules, scarcity, efficacy and deservingness perceptions; 2) Cross-national survey experiments to assess different aspects of rules in different contexts; 3) Quasi- and field experiments to assess the impact of rules on register measures of burdens in a real-world context. POAB offers a fundamentally new interdisciplinary approach by bridging the gap between research on administrative burdens and psychological perspectives. The project’s output will provide profound knowledge of citizens’ experiences of burden and the inequalities in such experiences among recipients of major welfare benefits.";1499611;1499611;ERC-2018-STG;/ERC-STG;AARHUS UNIVERSITET;DK;;;;1;0;0;1;0;0 220566;829005;IQubits;SIGNED;H2020-EU.1.2.1.;FETOPEN-01-2018-2019-2020;H2020;Integrated Qubits Towards Future High-Temperature Silicon Quantum Computing Hardware Technologies;2019-01-01;2022-12-31;;The objectives of the interdisciplinary project IQubits are to (i) develop and demonstrate experimentally high-temperature (high-T) Si and SiGe electron/hole-spin qubits and qubit integrated circuits (ICs) in commercial 22nm Fully-Depleted Silicon-on-Insulator (FDSOI) CMOS foundry technology as the enabling fundamental building blocks of quantum computing technologies, (ii) verify the scalability of these qubits to 10nm dimensions through fabrication experiments and (iii) prove through atomistic simulations that, at 2nm dimensions, they are suitable for 300K operation. The proposed 22nm FDSOI qubit ICs consist of coupled quantum-dot electron and hole spin qubits, placed in the atomic-scale channel of multi-gate n- and p-MOSFETs, and of 60-240GHz spin control/readout circuits integrated on the same die in state-of-the-art FDSOI CMOS foundry technology. To assess the impact of future CMOS scaling, more aggressively scaled Si-channel SOI and nitride-channel qubit structures will also be designed and fabricated in two experimental processes with 10nm gate half pitch. The latter will be developed in this project. The plan is for the III-nitrides (III-N) qubits to be ultimately grown on a SOI wafer, to be compatible with CMOS. Because of their larger bandgap, III-N hold a better prospect than Si and SiGe for qubits with larger coupling energy and mode energy splitting, and 300K operation. As a radical breakthrough, the fabricated qubits will feature coupling energies on the order of 0.25-1 meV corresponding to control frequencies in the 60-240GHz range, suitable for operation at 3–12 degrees Kelvin, two orders of magnitude higher than today's qubits. The tuned mm-wave circuits allow for 10-20ps spin control pulses which help to filter out wideband thermal noise and largely enhance the ratio between the gating and the decoherence times. Thermal noise filtering and fast control of the spin may lead to even higher temperature operation for a given energy-level splitting.;3324330;2688375;H2020-FETOPEN-2018-2019-2020-01;/RIA;AARHUS UNIVERSITET;DK;"FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS;CONSIGLIO NAZIONALE DELLE RICERCHE;MDLAB SRL;INSTITUTUL NATIONAL DE CERCETAREDEZVOLTARE PENTRU MICROTEHNOLOGIE;THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO";"EL;IT;RO;CA";;1;0;0;1;0;0 220549;829161;NCLas;SIGNED;H2020-EU.1.2.1.;FETOPEN-01-2018-2019-2020;H2020;NanoCrystals in Fibre Lasers;2019-01-01;2022-12-31;;"The NCLas project will introduce and develop a disruptive technology for the synthesis of glasses containing functional nanocrystals (NCs). It is based on a novel hybrid nanosintering process, which allows for the incorporation of a large variety of NCs and functionalization of glasses in different formats for various applications. Previous attempts to either grow NCs inside glass by a glass heat treatment or incorporate NCs during glass formation showed unconvincing results. In our nanosintering process, key enabling steps include reducing the sintering temperature, developing specialized NC core-shell structures and adjusting the glass composition, thus achieving a chemically inert environment and matching the refractive index of NCs and glass. This technology will be exploited to produce low-loss, NC-functionalized glass fibres. Fibre lasers are energy efficient and compact and offer maintenance-free operation, ultra-short pulses, high power, and low noise. Today’s commercial fibre lasers are fabricated from robust, durable silica glass. The operation of oxide fibre lasers can be extended to an enormous spectral range (~400–3000 nm) by doping oxide glasses with laser-active nanocrystals optimized for particular laser wavelengths, thus enabling a huge variety of new applications. We will demonstrate two highly relevant fibre lasers: (i) a Ti3\:sapphire-NC fibre laser tuneable around 800 nm for bio-photonic applications; (ii) a Pr3\:yttria-NC 1300-nm fibre laser enabling a much-awaited wavelength extension in telecommunications and also fitting into one of the biophotonic windows. The high risk of NCLas is mitigated by an interdisciplinary team with demonstrated experience in their fields and highly complementary backgrounds. We will address the project challenges in all its steps, from material synthesis to device demonstration. NCLas makes a significant contribution to Key Enabling Technologies such as Nanotechnology, Photonics and Advanced Materials.";2991126,25;2991126,25;H2020-FETOPEN-2018-2019-2020-01;/RIA;LEIBNIZ-INSTITUT FUER PHOTONISCHE TECHNOLOGIEN E.V.;DE;"AKADEMIA GORNICZO-HUTNICZA IM. STANISLAWA STASZICA W KRAKOWIE;LASOS LASERTECHNIK GMBH;FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.;UNIVERSIDAD DE CANTABRIA;UNIVERSITY OF SURREY";"PL;DE;ES;UK";;1;0;0;1;0;0 220558;828838;SoFiA;SIGNED;H2020-EU.1.2.1.;FETOPEN-01-2018-2019-2020;H2020;Soap Film based Artificial Photosynthesis;2019-01-01;2022-12-31;;We propose a radical breakthrough by developing economically viable solar fuel production technology, exploiting the surfactant self-assembly & proton transport properties of soap films. Producing renewable solar fuel by Artificial Photosynthesis (AP) is globally recognized as a promising solution to modern energy & environmental crisis with decisive social impacts, but there are critical roadblocks in technology development. SoFiA aims to initiate & consolidate a baseline of feasibility for soap film based AP technology and its future uses by establishing the essential proofs-of principle & foundational scientific underpinnings. We propose the concept of an economic artificial photosynthetic membrane in form of soap film with photo-catalytic functional surfaces, formed at the junction between dis-symmetric soap bubble pairs. Our technology is made scalable by the design concept of a dynamic stream of regenerative soap bubbles capable of handling large volumes of gas, continuously flowing through a light exposed conduit. SoFiA bridges three mutually exclusive disciplines of surfactant science, renewable energy and fundamental science of water at nanoscale, supported by micro-systems engineering, and by actively engaging artists who are working with large soap film installations. The high risk is countered by engaging pioneering scientists and globally leading young researchers in an interdisciplinary research plan. An External Advisory Board composed of program managers from large industry and EU policy experts will guide the research deliverable towards commercial exploitation. Our long-term vision is to decisively alter Europe’s position in the world economic map as the leading green energy producer. Developed technology will be jointly exploited by European energy and detergent industries, kick-starting new ventures & production facilities. Major environmental impact is expected as SoFiA is devoted to transform the primary greenhouse gas (CO2) into fuel.;3205280;3205280;H2020-FETOPEN-2018-2019-2020-01;/RIA;UPPSALA UNIVERSITET;SE;"UNIVERSITEIT LEIDEN;THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;UNITED NATIONS EDUCATIONAL, SCIENTIFIC AND CULTURAL ORGANIZATION -UNESCO;TECLIS INSTRUMENTS;POLITECNICO DI TORINO;MICROFLUIDIC CHIPSHOP GMBH;STICHTING NEDERLANDSE WETENSCHAPPELIJK ONDERZOEK INSTITUTEN";"NL;UK;FR;IT;DE";;1;0;0;1;0;0 220560;829047;triboREMEDY;SIGNED;H2020-EU.1.2.1.;FETOPEN-01-2018-2019-2020;H2020;The triboreactor as breakthrough remediation strategy for safeguarding human and environmental health;2019-03-01;2023-02-28;;"Environmental remediation for safeguarding human health is difficult. Effective processes enabling scalable operability are lacking. triboREMEDY aims at solving this impasse by providing the foundational steps towards the novel technology called “tribolysis” for safe, controlled, and efficient degradation of hazardous chemicals and effective inactivation of the pathogens. The scientific and technological breakthrough of triboREMEDY is based on the generation of nascent surfaces, high pressures, and shearing forces that will supply the required activation energy for dissociation of polychlorinated biphenyls (PCBs) and cell disintegration of pathogens. The centrepiece of triboREMEDY is the fully-controlled “triboreactor” in which mechanically (tribologically) induced chemical reactions take place as viable alternative to A) highly costly incineration or storage of hazardous waste, notably PCBs, and B) chemical, thermal inactivation or ultra-violet irradiation of pathogens in drinking water. The main project aim is to set scalable design rules for the “triboreactor” (proof of concept) based on the identification of PCB degradation products and pathogen inactivation pathways together with their relationships to operational parameters. In addition to this, the long-term vision beyond halogen elimination of PCBs and disinfection of drinking water avoiding chlorine treatments, will cover other toxic organic chemicals, application in chemical synthesis, catalysis free of critical raw materials, coating processes, requiring sensors for the monitoring of trace components, opening a wide new scientific and technological field. triboREMEDY will be driven by a multidisciplinary team of excellent researchers in mechanical engineering, chemistry, physics, biology, and medicine enabling the required unique breakthrough and interdisciplinary approach. In last FETOPEN call, triboREMEDY reached score 4.15/5.00 and the suggestion of evaluators were considered for this new application.";2831993,75;2831993,75;H2020-FETOPEN-2018-2019-2020-01;/RIA;FUNDACION TEKNIKER;ES;"LULEA TEKNISKA UNIVERSITET;MEDIZINISCHE UNIVERSITAET WIEN;UNIVERSITEIT ANTWERPEN;VRIJE UNIVERSITEIT BRUSSEL;AC2T RESEARCH GMBH;URTEK WATER TECHNOLOGIES SL";"SE;AT;BE;ES";;1;0;0;1;0;0 220552;828946;PATHOS;SIGNED;H2020-EU.1.2.1.;FETOPEN-01-2018-2019-2020;H2020;Photonic and nAnomeTric High-sensitivity biO-Sensing;2019-04-01;2024-03-31;;We plan to develop a radically new technology for the sensing of bio-systems and in-vivo diagnostics of biomedical conditions using hitherto unexploited tools of unconventional complex-system dynamical control and information sampling/processing. They will be founded on groundbreaking concepts and challenging experiments, with the following aims: (a) Magnetic-resonance imaging (MRI) and optically-detected magnetic-resonance (ODMR) sensing will be dramatically improved by orders of magnitude through highly selective cooling/suppression of thermal noisy background in-vivo with unprecedented spectral and spatial (subnano- or submicron-) resolution. It will be based on so far unemployed (but conceptually proven) stochastic (anti-) Zeno effects and collective-spin cooling pioneered by the partners of this very interdisciplinary consortium. (b) Development of novel probing configurations and protocols: NMR intra-molecule/intra-tissue sensing and intra-cell NV-center thermometry based on dynamical control being aimed at unravelling of hitherto invisible biochemical activity features masked by inhomogeneous broadening. (c) Advanced sensing-data processing, including high-order correlation spectroscopy – innovative strategies that seek to exploit dynamically controlled/modified noise in bio-systems as a source of previously untapped information on physiological (temporal) processes and anatomical (structural) detail. This information will be obtained by treating bio-systems as complex, noisy “environments” through novel probing/estimation procedures and compressed (sparse) imagery of the spectrally and spatially structured “environment”, but reducing drastically their complexity by dynamically controlling the relevant information encoded by key noise parameters. The overarching goal will be to substantially enrich the spatial and spectral information content and robustness of diverse medical diagnostic procedures and thereby minimize the exposure time/irradiation dosage.;2567500;2567500;H2020-FETOPEN-2018-2019-2020-01;/RIA;UNIVERSITA DEGLI STUDI DI FIRENZE;IT;"WEIZMANN INSTITUTE OF SCIENCE;ISTITUTO NAZIONALE DI RICERCA METROLOGICA;TECHNISCHE UNIVERSITAT DORTMUND;THE HEBREW UNIVERSITY OF JERUSALEM";"IL;IT;DE";;1;0;0;1;0;0 220564;828922;FRINGE;SIGNED;H2020-EU.1.2.1.;FETOPEN-01-2018-2019-2020;H2020;Fluorescence and Reactive oxygen Intermediates by Neutron Generated electronic Excitation as a foundation for radically new cancer therapies;2019-05-01;2023-10-31;;Deep lying tumours like aggressive brain cancer remain very difficult to treat and existing therapies offer only marginal increase in survival rates. In the case of photomedical therapies they are very effective, but mainly limited by their insufficient depth of light penetration into tissue. Current neutron-based therapies have sufficient penetration depth but suffer from lack of cancer specificity. In FRINGE we propose a genuinely new hybrid-technology. At its heart are chemical agents (photosensitisers - PS) which preferentially accumulate in the tumours especially in brain cancers where the blood brain barrier is compromised. The PSs designed for FRINGE will contain metal centres like Gadolinium (Gd), to enable interaction with incoming neutrons and facilitate the transfer of neutron energy into electron excitation of the PS, confirmed by concomitant fluorescence emission. Interaction with ambient oxygen will generate reactive oxygen species which will kill the tumour cells. The main scientific breakthrough of this project will be to establish experimental proof-of-principle of this novel neutron-activated therapy. FRINGE will combine the advantages of photomedical therapies (no mutagenic radiation) with the advantages of neutron-based therapies (large penetration depth). The externally-applied neutron beam can be energy-tuned to become therapeutic exactly at the depth of the tumour. Exploiting Gd as a contrast agent, FRINGE can also become a theranostic modality by use of magnetic resonance imaging. FRINGE has the potential of causing immunogenic cell death to cancers which could eliminate occult metastasis and act as a ‘cancer vaccine’. The highly interdisciplinary project team comprises world renowned experts from a unique combination of disciplines: Nuclear physicists, synthetic chemists, photochemists, photobiologists, medical physicists, quantum chemists and radio-oncologists will join forces to lay the foundations for a novel, curative cancer therapy.;3979485;3979485;H2020-FETOPEN-2018-2019-2020-01;/RIA;OSLO UNIVERSITETSSYKEHUS HF;NO;"UNIVERSITAT DE GIRONA;SYNTHETICA AS;VYSOKA SKOLA CHEMICKO-TECHNOLOGICKA V PRAZE;INSTITUTT FOR ENERGITEKNIKK;""NATIONAL CENTER FOR SCIENTIFIC RESEARCH """"DEMOKRITOS"""""";UNIVERSITAT POLITECNICA DE VALENCIA;ACCELOPMENT AG";"ES;NO;CZ;EL;CH";;1;0;0;1;0;0 194857;653383;IMPACT;CLOSED;H2020-EU.3.7.;DRS-21-2014;H2020;Impact of Cultural aspects in the management of emergencies in public Transport;2015-05-01;2017-10-31;;"The objective of the IMPACT project is to investigate the essential role played by cultural factors in managing safety- and security-issues related to emergencies in public transport systems. The IMPACT Coordination and Supporting Action is aimed at analysing the different cultural behaviours for the prevention of emergencies with particular emphasis on risk and situational awareness perception of the different cultural groups; information to passengers with different socio-cultural backgrounds; cooperation towards prevention of security threats; security checks. Moreover, it is aimed at analysing the different cultural behaviours for the management of emergency events and the post-events with particular emphasis on: crowd management; management of first responders to care for different cultural groups; information to passengers. From the above analyses IMPACT will produce a cultural risk assessment methodology and the associated mitigation actions for the public transport sector also developing simulators and models; identify innovative solutions that can support public transport operators in improving the communication with passengers through tailored messages to the different cultural communities (via mobile phones and social networks) and other solutions to enhance the management of emergencies considering cultural aspects; develop best practices, dedicated training material and procedures for both public transport operators and first responders; develop policy recommendations for policy makers, regulators, municipalities and public transport operators. The IMPACT Consortium has an intercultural and interdisciplinary approach with an extensive expertise in different disciplines, ranging from social and cultural psychology, sociology and anthropology, to safety, security and emergency management and from computer-science to communication and event organization. The consortium is composed by 2 SMEs, 1 big Industry, 4 Universities and 1 National Authority.";1398912,5;1398912,5;H2020-DRS-2014;/CSA;DEEP BLUE SRL;IT;"ANADOLU UNIVERSITY;STICHTING VU;PROPRS Ltd.;NUOVO TRASPORTO VIAGGIATORI SPA;UNIVERSITY OF LEEDS;URZAD MORSKI W GDYNI;VISSHE UCHILISHTE PO MENIDZHMANT";"TR;NL;UK;IT;PL;BG";;1;0;0;1;0;0 198443;647316;EUROPINIONS;SIGNED;H2020-EU.1.1.;ERC-CoG-2014;H2020;Causes and consequences of change in public opinion about Europe;2015-09-01;2020-08-31;;"Causes and consequences of change in public opinion about Europe Public opinion towards European integration and the EU is divided, especially in the wake of the economic crisis. From being a consensus issue with stable and broad elite and public support across the continent, it is now a contentious issue with swiftly changing opinions. EU opinions include utilitarian considerations, identity issues, and emotions. These EU opinions matter for voting behaviour and for the future course of the EU and European democracies. The future of European integration needs public support and yet we know little about what drives and changes this support: we need to know why some people change their opinions about European integration while others do not, and what the consequences of these changes are in terms of electoral behaviour. This project studies the causes and consequences of EU opinions. Opinions may change in response to real world developments, domestic political factors, and personal experiences, but very importantly also in response to new information such as provided by the media and in interpersonal and network communication. This project develops and tests a Communication Model of Public Opinion Change and Consequences. The key question underlying this project is when, how, for whom, and with which consequences communication matters for changes in public opinion about Europe? To address this question, an innovative and interdisciplinary design is needed. This will be done in five integrated subprojects, bringing together research on public opinion and political behaviour from the fields of political sociology, political communication, and political psychology. It employs a range of research techniques (novel survey methodology, (automated) content analyses, social media analysis, and experimentation) in a cross-nationally comparative design. The applicant is a leading expert in research on political communication, public opinion, and European integration.";2000000;2000000;ERC-2014-CoG;/ERC-COG;UNIVERSITEIT VAN AMSTERDAM;NL;;;;1;0;0;1;0;0 196115;661526;IMAGUS;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Styles of Objectivity: Agency, Alignment, and Automation in Image-Guided Surgery;2015-09-01;2017-08-31;;Advanced imaging technologies are currently transforming operating rooms into sophisticated augmented reality studios that explore recent developments in computer visualization, navigation applications, and robotic systems. The new imaging methods promise to increase precision and improve health outcomes. However, as medical diagnosis and therapy grow more dependent on images, the status and roles of these images become increasingly controversial. Image-guided applications reshape clinical practices, impact medical decisions, and transform the relationship between physician and patient. The objective of the project is to develop a new framework that accounts for the active role of images in surgical contexts, providing a systematic basis for handling the impact of these images and assessing their controversial aspects. The project pursues its goal through a collaborative and interdisciplinary effort that involves medical practitioners. It articulates the visual knowledge of medical practitioners by undertaking in-depth operational analyses of three image-guided technologies in current use: the 3D Slicer software application, the da Vinci surgical system, and the CyberKnife robotic radiosurgery system. The analyses introduce the notion of styles of objectivity, which accounts for the key features of these applications, including agency, alignment, and automation, while acknowledging that images have a certain agency and that there is an inner connection between aesthetic and epistemic factors. A second objective of the project is to contribute to conceptual and methodological innovation through a two-way transfer of visual literacies across medicine and humanities/social science domains, by operationalising the visual knowledge of surgical practitioners so that it can be fed into visual/media/science studies, and vice versa. This includes developing concepts for new ways of teaching the visual knowledge of medicine.;171460,8;171460,8;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;HUMBOLDT-UNIVERSITAET ZU BERLIN;DE;;;;1;0;0;1;0;0 195705;659022;GENMETASTEM;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;GENOMIC AND METABOLIC REGULATION OF METASTATIC CANCER STEM CELLS;2016-09-01;2018-08-31;;The major causes of cancer deaths are relapse and resistance to current therapies associated with the presence of cancer stem cells (CSCs) and metastatic growth in distant organs. CSCs have the ability to self-renew and differentiate in non-CSCs. In breast cancer, acquisition of stemness properties has been closely related to epithelial-mesenchymal transition (EMT), a key process in cancer invasion and metastasis triggered via Rho-ROCK mediated actomyosin contractility. Interestingly, in melanoma, transition from elongated-mesenchymal to amoeboid mode of movement (MAT) driven by Rho-ROCK signalling has been associated with increased stemness. Furthermore, preliminary data from host lab shows that actomyosin cytoskeletal regulates glutamine metabolism in both melanoma and breast cancer cells. Metabolic cues participate in stem cell self-renewal regulation, suggesting that, in very contractile cells, the regulation of EMT, metastatic spread and tumour initiation might be functionally linked to stemness via metabolic clues. Nevertheless, how very contractile cells regulate genes involved in all these processes remains unexplored. As increasing contractility via EMT in carcinoma cells or via MAT in melanoma cells correlates with increasing stemness, we hypothesize a molecular link between the pathways regulating both migration and stemness abilities, which will be maintained across tumour types (from carcinoma to melanoma). The main goal of this proposal is to understand how tumour cells can acquire stem cell traits to successfully metastasize and how this can be regulated by the actomyosin cytoskeletal by using an interdisciplinary approach that combines state-of-the-art techniques in molecular and cellular biology, biochemistry, in vivo imaging and animal models. This will allow to identify key important genes regulating both stemness traits and metastatic spread with the ultimate goal of unravelling novel drug targets and prognostic markers of distant relapse.;183454,8;183454,8;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;KING'S COLLEGE LONDON;UK;;;;1;0;0;1;0;0 220419;817564;CLIOARCH;SIGNED;H2020-EU.1.1.;ERC-2018-COG;H2020;Cliodynamic archaeology: Computational approaches to Final Palaeolithic/earliest Mesolithic archaeology and climate change;2019-09-01;2024-08-31;;Late Pleistocene/early Holocene Europe is said to be the ideal laboratory for the investigation of human responses to rapidly changing climates and environments, migration and adaptation. Yet, pinpointing precisely how and why contemporaneous Final Palaeolithic/earliest Mesolithic (15,000-11,000 years BP) foragers migrated, and which environmental or other factors they adapted to – or failed to – has remained remarkably elusive. At the core of ClioArch is the radical but, in light of research-historical insights, necessary hypothesis that the current archaeological cultural taxonomy for this iconic period of European prehistory is epistemologically flawed and that operationalisations and interpretations based on this traditional taxonomy – especially those that seek to relate observed changes in material culture and land-use to contemporaneous climatic and environmental changes – are therefore problematic. Hence, novel approaches to crafting the taxonomic building blocks are required, as are novel analyses of human|environment relations in this period. ClioArch’s premier ambition is to provide operational cultural taxonomies for the Final Palaeolithic/earliest Mesolithic of Europe and to couple these with interdisciplinary cultural evolutionary, quantitative ecological methods and field archaeological investigations beyond the state-of-the-art, so as to better capture such adaptations – almost certainly with major implications for the standard culture-historical narrative relating to this period. In so doing, the project will pioneer a fully transparent and replicable – and eminently transferable – methodology for the study of the impacts of climate change and extreme environmental events in deep history. In turn, such a quantitative understanding of past adaptive dynamics will position archaeology more centrally in contemporary debates about climate change, environmental catastrophe and their cultural dimensions.;1907638;1907638;ERC-2018-COG;/ERC-COG;AARHUS UNIVERSITET;DK;;;;1;0;0;1;0;0 220394;794852;TCRabX;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Structural basis for the therapeutic efficiency of optimal-affinity T cell receptors;2019-08-01;2022-07-31;;Demographic change includes population ageing, and incidence rates begin to increase for many types of cancer in middle-aged and elderly people. Traditional cancer treatment includes surgery, chemotherapy, and radiation therapy, while tumour immunotherapy by T cell receptor (TCR) gene transfer represents an alternative form of treatment. The transfer of tumour-specific TCR genes into patient’s peripheral blood lymphocytes targets cancer specifically and effectively. But while patient-derived low-affinity TCRs do not show therapeutic activity, optimal-affinity TCRs, as isolated from newly-generated antigen-negative humanized mice with a diverse human TCR repertoire, can effectively delay tumour regression. X-ray crystallography is a powerful tool of structural biology, which helps researchers to identify the three-dimensional (3D) structures of biological macromolecules such as TCRs complexed to their cognate peptide-loaded major histocompatibility complex (pMHC) molecules. Recent research uncovered the docking topologies of naturally selected TCRs, but therapeutically efficient optimal-affinity TCRs recognizing tumour-associated self-antigens, have not been analysed to date. The exceptional specificity of TCRs is determined by three complementarity-determining regions (CDRs) of the TCR alpha- and beta-chains. Biomedical research on TCR gene therapy and design of future clinical trials will hugely benefit from the identification of CDR-mediated contact points made between therapeutic TCRs and the pMHC on their target cells. TCRabX is an interdisciplinary research project investigating the 3D structures of 13 TCRs complexed to MHC-I or MHC-II, respectively. It connects innovative clinical immunology research in Berlin/Germany and world-class structural biology research in Melbourne/Australia. The proposed research will enhance the health and well-being of citizens in Europe and worldwide by supporting the advancement of cancer immunotherapy approaches.;264110,4;264110,4;H2020-MSCA-IF-2017;/MSCA-IF-GF;CHARITE - UNIVERSITAETSMEDIZIN BERLIN;DE;;;;1;0;0;1;0;0 201026;702285;BigERRORS;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-GF;H2020;Exploring the promise of big data for medical error elimination;2016-08-01;2018-07-31;;Errors in hospitals pose serious threats to human lives and affect total costs. Big data research is fast becoming a tool that not only analyzes patterns but can also provide the predictive likelihood of an event. Big data may be a great opportunity to make data an engine to dramatically decrease error rates in hospital. However, there is very little published research literature that tackles the challenges of using big data in organizations and explores the promise and opportunities for new theories and practices that big data might bring about. The overriding objective of this proposal is to explore the promise of big data for eliminating and managing errors in hospitals. The beneficiary, Prof Eitan Naveh from the Technion – Israel Institute of Technology, is a world leading researcher in the area of errors. The partner organization is Harvard University. The partnership member from Harvard is Prof Sara Singer, a world-class leading Professor of Health Policy and Management at Harvard’s T.H. Chan School of Public Health. Prof Naveh will spend the first year of the research project in Harvard and will be hosted by Prof Singer. During the fellowship, Prof Naveh will obtain training and new knowledge in Harvard’s exciting environment, and specifically in Prof Singer’s new health care High Reliability Learning Lab. Prof Naveh will gain training and new knowledge that refers to new interdisciplinary scientific techniques and transferable skills in big data, and will set a new research agenda for the science of errors in hospitals. The competences Prof Naveh will gain will allow new state-of-the-art research with opportunities to practice and improve health care. Prof Naveh will develop a network to communicate and disseminate the study’s results and to realize its exploration and developments.;177319,8;177319,8;H2020-MSCA-IF-2015;/MSCA-IF-GF;TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY;IL;;;;1;0;0;1;0;0 212613;744835;AgeCogCity;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;How visual perception shapes our cities: a cognitive model of ageing population;2018-10-01;2020-09-30;;Two mega-trends – the rapid urbanisation of the world’s population and the ageing of that same population – will soon collide. Adapting to the challenges of elderly citizens (many of whom no longer drive), urban designers need appropriate tools to support planning for walking, the most environmentally, socially, and economically sustainable transport mode. Cities’ walkability depends not only on physical settings, but also on processes of human spatial cognition, in particular visual perception. However, current state of art methods in modelling and forecasting urban systems are based mainly on economic and transportation demands and ignore pedestrians’ spatial cognition. This research discovers how visuo-spatial cognition contributes to the generation of new urban uses and activities based on the age profile of the user population. It constructs a novel urban-behavioural paradigm that links built environment and the way people use it, by addressing three fundamental questions: (1) What are the most important visuo-spatial properties influencing pedestrian cognition? (2) How urban visibility could be encoded and analysed as an abstracted spatial representation (visibility network)? (3) What mechanisms allow cities to be generated through feedback reflected in pedestrian movement and urban visibility? These questions are answered using an interdisciplinary approach: It combines quantitative techniques for spatial modelling with qualitative strategies for tracing of pedestrian behaviour in Immersive Virtual Reality (IVR). The research findings will set a framework for the evidence-based tool to assist planners, architects and stakeholders in the design and evaluation of urban projects in view of the changing needs of urban population.;195454,8;195454,8;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;UNIVERSITY COLLEGE LONDON;UK;;;;1;0;0;1;0;0 214100;792270;DNA-ENC SYNCELLS;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;DNA Lattice-Encoded Information for Genotype-to-Phenotype Evolution of Self-Replicating Synthetic Cells;2018-03-01;2020-02-29;;Within the framework of DNA-ENC SYNCELLS I will develop a synthetic inheritable genome capable of Darwinian evolution which encodes for the phenotype of self-replicating synthetic cells. The defining principles of life, namely compartmentalisation, replication and evolution, will thus be realised in a completely synthetic system for the first time. Two types of DNA tiles – a stiff and a soft tile – arranged in a lattice will serve as bits of information, replicating, without any enzymes, via mechanical scission. The DNA lattice will further act as an artificial cytoskeleton specifying the mechanics and shaping the phenotype of synthetic compartments assembled on a microfluidic chip. After sequentially adding the DNA tiles and catalysts for lipogenesis, the synthetic cells will be subjected to multiple growth and mechanically initiated division cycles. Variations in the mechanical properties will influence the division rate and thus lead to evolution in heterogeneous populations. The evolutionary trajectory of the system will be studied under different selection pressures. Within this two-year fellowship, hosted at the Max Planck Institute for Medical Research in Heidelberg and supervised by Prof. Joachim Spatz, I will contribute to the fundamental knowledge of synthetic cells and enhance its applicability using programmable man-made materials. Greatly profiting from the synergy between my expertise on DNA nanotechnology and the host’s high-quality research on microfluidics, synthetic biology and biophysics, this interdisciplinary project will open up broad perspectives for cellular machines capable of autonomous cargo transport, pathogen recognition or as substrates for 3D-bioprinting and tissue repair in vitro and in vivo – the envisioned focus of my subsequent career in research.;159460,8;159460,8;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;DE;;;;1;0;0;1;0;0 208921;747339;ReCyPot;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Revisiting an ancient craft in a contested region: The analytical paradigm of prehistoric pottery from Cyprus;2018-02-01;2020-01-31;;ReCyPot is a large-scale, interdisciplinary study of ancient ceramics from the region of Lapithos on the northern coast of Cyprus that addresses four different themes of cross-cultural and cross-regional significance: 1) ancient technology, 2) ancient Mediterranean history and archaeology, 3) the restudy of older excavated material with new methods of analysis and interpretation and 4) the study of ancient artefacts from areas presently inaccessible to archaeological and historical research. Integrating ceramic petrography and methods of chemical and microstructural analysis (including WD-XRF, NAA and SEM), this will be a thorough analytical study of ancient pottery, dated to the end of the third millennium and the second millennium BC, the comparative analysis of contemporary pottery from the region, as well as ceramics from intervening periods in Lapithos. While the project deals with a specific region on the island of Cyprus, it can be used as an exemplar for addressing broader, cross-cultural and methodological questions regarding the definition and recording of pottery traditions, how these are transformed and how modern archaeologists can perceive and study them. The project will attempt to reconstruct the ancient pottery traditions of Lapithos and define those compositional and technological elements that form the Lapithos ceramic profile. Beyond the definition of regional ceramic traditions and elements of stability and change through time, this project will consider environmental, technological, sociocultural and historical factors that must have had an impact on ceramic production, distribution and consumption. Pottery production will be integrated into its regional and inter-regional socio-economic context, and provide an insight into the ancient society and history of the region, an integral part of the ancient Mediterranean.;195454,8;195454,8;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;UNIVERSITY COLLEGE LONDON;UK;;;;1;0;0;1;0;0 210256;742102;QUENOCOBA;SIGNED;H2020-EU.1.1.;ERC-2016-ADG;H2020;Quantum Emitters in non-conventional baths;2017-09-01;2022-08-31;;"The coupling of quantum emitters to a common bath gives rise to intriguing quantum optical phenomena, like super-radiance, non-Markovian dynamics, or dipole-dipole interactions. In recent years, new experimental setups are emerging where non-conventional baths, with tailored dispersion relations, can be produced. In particular, atoms (the emitters) can be kept in the proximity of photonic crystals (the bath), whose properties can be engineered thanks to the spectacular progress experienced in nano-fabrication techniques. Low dimensional mate- rials, dispersion relations with Dirac points, or exotic topological features can be designed in photonic crystals, which will dramatically affect the behavior of the emitters. In this scenario, exotic phenomena, unique possibilities for quantum simulation of both coherent and dissipa- tive dynamics, as well as advanced applications are expected to appear. Presently, a new research area is emerging to investigate the physics of emitters coupled to non- conventional baths. In this project we will: (i) develop the theoretical tools required to investigate this new area; (ii) explore and characterize novel phenomena; and (iii) propose and analyze other physical setups where those phenomena can be observed and exploited (in the context of quantum information and simulation). The research will involve the development of innovative tech- niques to describe new scenarios in quantum optics and many-body physics, as well as re- search on atoms interacting with photonic crystals, in optical lattices, and quantum dots in- teracting with surface acoustic waves. This interdisciplinary project involves concepts and ideas from quantum optics, many-body quantum physics, and quantum information, research fields where the PI has a vast experi- ence. This, together with a close collaboration with leading experimentalists will provide us with a unique environment for the successful accomplishment of the objectives of the project.";1872968,75;1872968,75;ERC-2016-ADG;/ERC-ADG;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;DE;;;;1;0;0;1;0;0 210990;742432;BRCA-ERC;SIGNED;H2020-EU.1.1.;ERC-2016-ADG;H2020;Understanding cancer development in BRCA 1/2 mutation carriers for improved Early detection and Risk Control;2017-09-01;2022-08-31;;"Recent evidence demonstrates that cancer is overtaking cardiovascular disease as the number one cause of mortality in Europe. This is largely due to the lack of preventative measures for common (e.g. breast) or highly fatal (e.g. ovarian) human cancers. Most cancers are multifactorial in origin. The core hypothesis of this research programme is that the extremely high risk of BRCA1/2 germline mutation carriers to develop breast and ovarian cancer is a net consequence of cell-autonomous (direct effect of BRCA mutation in cells at risk) and cell non-autonomous (produced in distant organs and affecting organs at risk) factors which both trigger epigenetic, cancer-initiating effects. The project’s aims are centered around the principles of systems medicine and built on a large cohort of BRCA mutation carriers and controls who will be offered newly established cancer screening programmes. We will uncover how ‘cell non-autonomous’ factors work, provide detail on the epigenetic changes in at-risk tissues and investigate whether these changes are mechanistically linked to cancer, study whether we can neutralise this process and measure success in the organs at risk, and ideally in easy to access samples such as blood, buccal and cervical cells. In my Department for Women’s Cancer we have assembled a powerful interdisciplinary team including computational biologists, functionalists, immunologists and clinician scientists linked to leading patient advocacy groups which is extremely well placed to lead this pioneering project to develop the fundamental understanding of cancer development in women with BRCA mutations. To reset the epigenome, re-establishing normal cell identity and consequently reducing cancer risk without the need for surgery and being able to monitor the efficacy using multicellular epigenetic outcome predictors will be a major scientific and medical breakthrough and possibly applicable to other chronic diseases.";2497841;2497841;ERC-2016-ADG;/ERC-ADG;UNIVERSITY COLLEGE LONDON;UK;UNIVERSITY COLLEGE LONDON HOSPITALSNHS FOUNDATION TRUST;UK;;1;0;0;1;0;0 219603;803077;PHARMS;SIGNED;H2020-EU.1.1.;ERC-2018-STG;H2020;Bacteriophage inhibition of antibiotic-resistant pathogenic microbes and founding for novel therapeutic strategies;2019-01-01;2023-12-31;;"Emergence of antimicrobial resistance (AMR) is a grand scientific challenge of our time that has killed more than 700,000 people worldwide. Phage therapy, a promising complement to antibiotics, utilizes viruses of bacteria (bacteriophages) or phage-derived inhibitors as natural ways to fight AMR. The main obstacles in the clinical application of phage-based AMR therapy are the limited number of phage isolates and the unknown molecular mechanisms of phage-delivered bactericidal action. Building on the recent advances of my group in high-throughput, culture-independent but host-targeted methodologies, PHARMS aims to deploy a revolutionary approach: to screen for all possible phages of a resistant bacterial isolate, characterize multiple lines of their bactericidal functions, and use this information for the design of a whole battery of phage-based therapies that employ multifaceted modes of action. Using an interdisciplinary research plan, PHARMS will discover phage-specific bactericidal action modes at all possible levels ranging from nucleotide sequence and transcription to translation, in order to elucidate the molecular mechanisms driving phage-mediated inhibition of AMR Acinetobacter baumannii, Helicobacter pylori, & Haemophilus influenzae (WP1). These discoveries, together with novel synthetic biology tools, will enable us to engineer an array of phage vectors that mimic phage-deployed bactericidal modes discovered under WP1, including transport of alien genes to deliver bactericidal effects (WP2). PHARMS will provide molecular confirmation and in vitro & in vivo validation of the functions of phage-encoded bactericidal peptides and enzymes (WP3). By elucidating universal and specific mechanisms of phage-delivered inhibition of AMR pathogens, PHARMS is positioned to provide the rational framework for the design of novel therapeutic strategies aimed at treating common and life-threatening infectious diseases.";1499650;1499650;ERC-2018-STG;/ERC-STG;HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH;DE;;;;1;0;0;1;0;0 194839;653240;STRESSAGED;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Molecular Mechanisms Linking Psychological Stress and Ageing-Related Disease;2015-05-01;2017-04-30;;Ageing-related diseases are the leading causes of morbidity and mortality. A ubiquitous and potentially preventable factor predisposing to their development is psychological stress, but the molecular mechanisms underlying this relation are largely unknown. This knowledge gap is addressed by the proposed project, which examines epigenetic modifications and, in particular, DNA methylation changes as molecular signatures that may be induced by lifetime stressors and act in concert with advancing age to shape disease risk. The proposed fellow will first identify the DNA methylation sites that are regulated by stressors and ageing and will then examine how these epigenomic sites determine gene expression and disease outcomes. Among key biological processes, the project will focus on immune dysregulation, a common pathogenic process for several diseases of the ageing. Immune dysregulation will be examined in the periphery but also in the brain, the orchestrator of behavioral, neuroendocrine and immune responses. The project will engage translational approaches using both human samples and animal models, implemented via collaborations among leading institutions and experts in Europe and USA. The applicant has unique interdisciplinary skills to carry out the project, including clinical background as well as experience in both clinical and basic research projects on the two fields brought together in the proposal, the biology of stress and ageing-related diseases. The impact of the project can be tremendous, since elucidating the molecular mechanisms of ageing-related diseases would contribute to the development of biomarkers, targeted prevention strategies and novel treatments for these devastating diseases.;159460,8;159460,8;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;DE;;;;1;0;0;1;0;0 198646;649024;RegEvolve;SIGNED;H2020-EU.1.1.;ERC-CoG-2014;H2020;Comparative analysis of planarian regeneration - why some worms regenerate while others don’t;2015-10-01;2020-09-30;;"The ability to regenerate lost body parts is widespread amongst animals, yet humans, for example, can only regenerate specific organs. Why some animals regenerate while others hardly do remains a fascinating conundrum, especially so in face of “survival of the fittest”. Even amongst planarian flatworms, famous for their ability to regenerate from random tissue fragments, species exist that have completely lost the ability to regenerate. This proposal will exploit the unique diversity of planarian regenerative abilities amongst to ask why some worms regenerate while others do not. We and others have established that planarian Wnt signalling acts as critical node in the evolution of regeneration defects. Using this finding as strategic focus for comparisons between regenerating and non-regenerating species, we will investigate i) the cell biological mechanisms that shape Wnt pathway activity; ii) the genomic mechanisms that differentially deploy critical pathway regulators; and iii) evolutionary mechanisms in form of life history trait trade-offs as possible driving force behind the drift of regenerative abilities. Key to the project is a diverse collection of regenerating and regeneration-deficient species that my lab has established. Focused comparisons between our two primary model species D. lacteum and S. mediterranea, employing pan-planarian antibodies and functional genomics, will allow us to understand the detailed causes of altered pathway activity. Comparisons amongst the entire collection of 50 species will provide the necessary breadth for identifying and studying the evolutionary principles that “naturally select” regeneration-deficient planarians. The comparative approach of RegEvolve will thus uniquely bridge the proximate (molecular)- with the ultimate (evolutionary) causes of regeneration defects and such interdisciplinary endeavour between molecular and evolutionary regeneration research will lead to new and profound insights into both fields.";2000000;2000000;ERC-2014-CoG;/ERC-COG;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;DE;;;;1;0;0;1;0;0 214939;789040;DistriBrainRep;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Studying brain representations as a distributed process: from neural code to behavior;2019-06-15;2021-06-14;;We know coffee not only by its taste, but also by its name and association with caffeine. How our brains enable this association between stimulus-aspects and guides our behavior accordingly (e.g. determining whether we should drink coffee or discuss it) is one of the core questions of cognitive neuroscience. Neuroimaging research of brain activity indeed confirm that the brain simultaneously processes stimuli across distributed areas, each selective for a specific stimulus aspect. However, the computational research of stimulus representations (how fine-grained activity patterns relate to specific stimuli), is currently constrained to the detailed inspection of isolated brain areas. The proposed project offers a new formalism and method that may link these two research streams, initiating the study of representations as a distributed neural process. By combining the computational and experimental knowledge of the host with the functional Magnetic Resonance Imaging (fMRI) expertise of the researcher, the proposed project aims to reveal: 1) what computational principle underlies representations of different stimulus-aspects across brain areas, 2) whether distributed representations can co-express to form an overall knowledge of a stimulus, and 3) what mechanism regulates the expression of representations to allow flexible behavior. These questions will be addressed by studying brain activity evoked by stimuli composed of multiple aspects (visual, phonetic, associative) and by drawing from fMRI, brain stimulation and computational methods. Hence, the proposed work will provide the researcher with diverse training-through-research and a platform for establishing interdisciplinary collaborations. Expected results may bridge between the two major streams of cognitive neuroimaging to form a new understanding of how neural computations underlie distributed cognitive processes, which in turn gives rise to complex human behavior.;195454,8;195454,8;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;UNIVERSITY COLLEGE LONDON;UK;;;;1;0;0;1;0;0 212633;749206;TRAUMA_CONTEXT;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Looking at it from a different angle: The role of viewpoint-dependency in traumatic intrusions.;2018-04-01;2020-03-31;;"Many victims of psychological trauma suffer from recurrent intrusive trauma memories. According to Dual-Representation Theory (DRT), intrusive memories reflect functional deficiencies in the brain’s hippocampal system, which fails to translate the egocentric perceptual impressions of the trauma into viewpoint-independent (or allocentric) spatial representations. This proposal tests this assumption and explores allocentric memory training as a potential novel intervention against intrusive memories. I propose to induce intrusive memories in healthy participants using aversive scenarios in real-time 3D Virtual Reality, and to afterwards test location memory from the original versus a shifted viewpoint, requiring allocentric memory. Study 1 links allocentric memory to intrusion levels. Study 2 explores the potential of an allocentric memory training. Furthermore, both studies will assess the potentially moderating role of hormonal and sympathetic stress markers known to affect hippocampal learning. The project will provide novel insights into mechanisms of trauma memory, with potentially important implications for theory and treatment. It will be conducted in Prof. Chris Brewin’s research group at University College London (UCL) that is renowned for empirical tests of DRT specifically, and for world-leading expertise in clinical, experimental, neurocognitive and neuroendocrine approaches to psychology, providing an inspiring environment that perfectly fits the interdisciplinary character of this project.";183454,8;183454,8;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;UNIVERSITY COLLEGE LONDON;UK;;;;1;0;0;1;0;0 214534;798235;DYNAMET;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Interplay of plant one-carbon metabolism and redox homeostasis in the context of dynamic DNA methylation (DYNAMET);2018-06-01;2020-05-31;;"DNA methylation patterns in natural population are influenced by environmental factors and may be involved in selection of complex traits. Accordingly, there is growing interest to exploit epigenetic variation for crop improvement, a goal of utmost social importance considering the rapidly expanding world population and agricultural challenges from climate change. To better assess the use of epigenetic variation for crop improvement, it is crucial to know more about the dynamics of DNA methylation and the involved mechanisms. DNA methylation is stably maintained during DNA replication to faithfully silence transposable elements and thereby ensure genome integrity. However, recent studies indicate that DNA methylation changes in plants that have been caused by environmental factors, including pathogens, heat, and drought may contribute to resistance against recurring stress. The aim of this proposal is to further elucidate the regulatory mechanisms of dynamic DNA methylation and their effects on plant fitness under environmental stress. We will address this aim by studying the interaction of one-carbon (C1) metabolism, redox homeostasis, and epigenetic regulation. C1 metabolism provides the methyl donor S-adenosylmethionine required for DNA methylation. Accordingly, perturbations in C1 metabolism can drastically affect genome-wide DNA methylation patterns and transcriptional gene silencing. C1 metabolism is tightly connected to redox homeostasis and key enzymes in C1 metabolism are regulated by redox-dependent post-translational modifications. Notably, redox changes are hallmarks of stress responses. Therefore, our objective is to investigate how stress-induced redox changes are linked to alterations in C1 metabolism and epigenetic regulation in the model plant Arabidopsis thaliana and in barley. The interdisciplinary approach will facilitate the discovery of new regulatory mechanisms involved in plant acclimation and reveal their potential in crop improvement.";171460,8;171460,8;H2020-MSCA-IF-2017;/MSCA-IF-EF-RI;HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH;DE;;;;1;0;0;1;0;0 218023;813327;ChromDesign;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2018;H2020;Chromatin architecture and Design;2018-09-01;2022-08-31;;"ChromDesign is an innovative and interdisciplinary network of 10 European academic and private institutions that will characterize how 3D chromatin organization affects gene regulation during cellular differentiation and in several human disorders. We will train 13 Early Stage Researchers (ESR), equipping them with the skills, knowledge, expertise, and enthusiasm necessary to develop successful future careers in the biomedical field (in academia or the private sector). Together with European experts in chromatin biology, 3D genomics, and research design, these ESRs will work towards the goal of identifying novel alterations in chromatin topology responsible for cellular malfunctions to: i) develop new diagnostic tools, ii) effectively communicate research results through specific toolkits; and iii) identify novel therapeutic targets with the potential to be exploited as treatments. Alteration of gene regulation occurs naturally during aging and underlies several human diseases. Its better characterization requires a deeper understanding of the spatial organization of the genome. We will investigate how the genome organizes in 3D over time, and how the 3D organization is related to gene regulation in health and disease. We will use and develop technologies in imaging, cell biology, genomics, and computational modelling and will focus on translating our results into clinical applications. ESRs will thereby receive training with state-of-the-art technologies in distinct research areas and in modules with theoretical and hands-on sessions on transferable skills: entrepreneurship, management, communication, and outreach. ChromDesign comprises 6 work packages: WP1–4 address the 4 main areas of chromatin biology and 3D genomics; WP5 applies the knowledge obtained from WPs1–4 into translational research; WP6 develops (with a dedicated ESR) a set of design toolkits for communicating results to scientists, the public, and schools; and WP7 ensures quality training for ESRs.";3430220,76;3430220,76;H2020-MSCA-ITN-2018;/MSCA-ITN-ETN;FUNDACIO CENTRE DE REGULACIO GENOMICA;ES;"ISTITUTO EUROPEO DI ONCOLOGIA SRL;HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH;FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION;DIAGENODE;FUNDACIO PRIVADA ELISAVA ESCOLA UNIVERSITARIA;KOBENHAVNS UNIVERSITET;INSTITUT CURIE;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS";"IT;DE;CH;BE;ES;DK;FR";;1;0;0;1;0;0 208715;752149;InvasiveSDM;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Frontiers in invasive species distribution modelling: incorporating human-associations and intraspecific niche structure to improve risk predictions.;2017-07-15;2019-07-14;;Biological invasions represent a major component of global change through their impacts on biodiversity, ecosystems and societies. Awareness of biological invasion impacts and the critical importance of evidence-based decision making have led to a persistent effort to understand the factors driving invasion success so as to be able to predict invasion outcomes. To this end, a range of modelling tools has been developed. Among them, species distribution models (SDMs) -phenomenological models that statistically relate observed species occurrences to environmental variables- play a critical role in invasion risk assessments. These models rely on ecological niche theory, which predicts that for recent events such as biological invasions, conservatism of the climatic niche is expected. However, recent studies have demonstrated that this approach could be hampered by apparent niche shifts in invasive ranges. Mismatches between native and invasive distributions derived from SDMs have been often interpreted as species adaptations in response to selection pressures in novel environments. However, methodological drawbacks of previous approaches fuel doubts about the biological meaning of these findings. In this project, two unresolved challenges faced by SDMs when applied to the biological invasion process will be examined: how (1) species’ association with human-modified habitats in native ranges and (2) intraspecific niche variation shape the distribution of invasive species at biogeographical scales and how these effects influence the reliability of predictions of invasion risk. To accomplish these goals, I will use an interdisciplinary approach combining global bird distribution data, with molecular phylogenetic data and modern statistical and ecological analyses. The results of the project will contribute to improve prediction accuracy of biological invasions, and will also help better understand the invasion process.;195454,8;195454,8;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;UNIVERSITY COLLEGE LONDON;UK;;;;1;0;0;1;0;0 211740;765911;RealVision;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2017;H2020;Hyperrealistic Imaging Experience;2018-01-01;2021-12-31;;The aim of realistic digital imaging is the creation of high quality imagery, which faithfully represents the physical environment. The ultimate goal is to create images, which are perceptually indistinguishable from a real scene. The RealVision network brings together leading universities, centers focused on industrial development and companies in Multimedia, Optics, Visual Communication, Visual Computing, Computer Graphics and Human Vision research across Europe, with the aim of training a new generation of scientists, technologists, and entrepreneurs that will move Europe into a leading role in innovative hyper-realistic imaging technologies. Current imaging technologies capture only a fraction of visual information that the human eye can see. The colours and dynamic range are inadequate for most real-world scenes and not all depth cues required for natural 3D vision are captured. This limits the realism of the experience and has hampered the introduction of 3D technology. Advancement in imaging technologies makes it possible to circumvent these bottlenecks in visual systems. As a result, new visual signal-processing areas have emerged such as light fields, ultra-high definition, highframe rate and high dynamic range imaging. The novel combinations of those technologies can facilitate a hyper-realistic visual experience. This will without doubt be the future frontier for new imaging systems. However there are several technological barriers that need to be overcome as well as challenges in what are the best solutions perceptually. The goal of this network is to combine expertise from several disciplines as engineering, computer science, physics, vision science and psychology – usually disconnected – and train ESRs to be capable of working with all stages and aspects of visual processing to overcome existing interdisciplinary and intersectorial barriers to efficiently develop truly perceptually better visual imaging systems.;4076702,28;4076702,28;H2020-MSCA-ITN-2017;/MSCA-ITN-ETN;DANMARKS TEKNISKE UNIVERSITET;DK;"THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;FORCE TECHNOLOGY;FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;DXO LABS;BANG & OLUFSEN AS;UNIVERSITE DE NANTES;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;BANGOR UNIVERSITY";"UK;DK;DE;FR";;1;0;0;1;0;0 214727;772994;FeedHypNet;SIGNED;H2020-EU.1.1.;ERC-2017-COG;H2020;Dynamic regulation of feeding behaviors in health and disease by top-down control of hypothalamic networks;2018-04-01;2023-03-31;;"Feeding behaviors represent a complex set of crucial for survival abilities required to meet upcoming nutritional demands. Eating disorders, such as anorexia nervosa, are widespread, difficult to treat and extremely dangerous, displaying the highest mortality rate of all psychiatric disorders and a very high relapse rate. Mechanisms of onset, progression and relapse of eating disorders are unknown. Feeding behaviors are regulated by hypothalamus, an evolutionary conservative brain region. While a role of neurochemically defined hypothalamic neurons in feeding has been recently studied, little is known about an adaptive regulation of hypothalamus by extrahypothalamic inputs. Further, it is not known how dynamic signaling in hypothalamus upon changing metabolic and environmental demands is organized to generate consistent adaptive behavior. The overarching goal of my proposal is to provide insight into neural mechanisms of healthy and pathological feeding behaviors. Combining optogenetics, electrophysiological recordings in transgenic behaving mice, Ca2\ imaging and fiber photometry, I will pursue 4 aims: (i) investigate role of neural circuitries that translate cognitive-related information to the lateral hypothalamus during adaptive feeding behaviors; (ii) characterize causal significance of top-down inputs from anxiety- and mood-related brain regions onto lateral hypothalamus in feeding, and study how changes in metabolic demands affect this signaling; (iii) study mechanisms and functions of fast, network oscillations-related and behavior-dependent signaling in hypothalamus; (iv) investigate how signaling in hypothalamus changes during development of anorexia nervosa symptoms and study consequences of optogenetically restored physiological signaling. This innovative and interdisciplinary approach will enable identification of neuronal circuits mediating feeding behavior in health and pathology, and thus gain insights into neuronal mechanisms of eating disorders.";1875000;1875000;ERC-2017-COG;/ERC-COG;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;DE;;;;1;0;0;1;0;0 212639;749988;ViMoAct;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Modelling cortical information flow during visuomotor adaptation as active inference in the human brain;2017-11-01;2020-05-02;;"Recent research suggests that to control bodily movements the brain relies on Bayes-optimal predictive models that are updated by sensory prediction error. This assumption may be generalised within a new formal account of motor control as active (Bayesian) inference. Active inference explains motor control in terms of hierarchical Bayesian filtering or predictive coding, i.e., as belief updating and suppression of prediction error to optimise a hierarchical generative model in the brain; thereby the weighting of prediction errors by their predicted precision determines their relative impact on hierarchical inference. This novel proposal still lacks concrete empirical investigation. The proposed project will close this research gap by testing whether cortical information flow during manual actions, requiring visuomotor adaptation and cognitive control of attention, follows the principles of active inference. In two fMRI experiments and one MEG experiment, participants will move a photorealistic virtual hand model via an MR-compatible data glove to perform simple manual tracking tasks in a virtual reality environment. The precision of prediction errors at multiple levels of a previously established cortical motor control hierarchy will be experimentally manipulated via visuoproprioceptive conflicts (introduced by delayed visual movement feedback) and via attentional allocation – either stimulus-driven (via increased sensory noise) or endogenous (instructed) – to visual or proprioceptive movement feedback. Active inference’s specific predictions about information flow between and within cortical areas will be tested with recently established dynamic causal modelling of the modelled hemodynamic (fMRI) or spectral (MEG) responses. Active inference appeals to a general free-energy principle of brain function; this contribution will thus promote interdisciplinary exchange of knowledge about self- and world-representation in the brain and will be of general public interest.";183454,8;183454,8;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;UNIVERSITY COLLEGE LONDON;UK;;;;1;0;0;1;0;0 211883;765148;TRABIT;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2017;H2020;Translational Brain Imaging Training Network;2017-10-01;2021-09-30;;"Brain diseases account for one third of the overall disease burden in Europe, and their already significant cost to society is expected to further escalate as a result of the aging European population. In recent decades, medical imaging techniques such as computed tomography, ultrasound, and especially magnetic resonance imaging have gained a central role in the clinical management of disorders of the brain. A fundamental bottleneck in translating the wealth of information contained in medical images into optimized patient care is the lack of computational tools to reliably and accurately analyze the available images. Combined with the sheer volume of data acquired on a daily basis, the current dearth of computational tools means that most of the relevant information contained in today's clinical brain scans simply remains unused. In an interdisciplinary and intersectoral joint effort of computational scientists, clinicians, and the industry in the field of neuroimaging, the 'Translational Brain Imaging Training Network' (TRABIT) aims to provide a new generation of innovative and entrepreneurial early-stage researchers (ESRs) to bring quantitative image computing methods into the clinic, enabling improved healthcare delivery to patients with brain disease. The proposed network brings together internationally leading groups in biomedical image computing; some of Europe's most renowned research hospitals; and important players from the medical imaging industry. Through this network, each of TRABIT's ESRs will have access to the most relevant experts from industry, academia, and hospitals, as well as large collections of clinical neuroimaging data, facilitating the evaluation of the true clinical relevance and impact of the investigated computational methods. A commonly adopted rapid-prototyping software environment will facilitate testing, demonstrating the developed tools in hospital environments, and disseminating the obtained models and methods.";3938655,6;3938655,6;H2020-MSCA-ITN-2017;/MSCA-ITN-ETN;DANMARKS TEKNISKE UNIVERSITET;DK;"MEDIZINISCHE UNIVERSITAET WIEN;ICOMETRIX NV;REGION HOVEDSTADEN;FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.;TECHNISCHE UNIVERSITAET MUENCHEN;ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE;UNIVERSITY COLLEGE LONDON;PHILIPS MEDICAL SYSTEMS NEDERLAND BV;TECHNISCHE UNIVERSITEIT EINDHOVEN";"AT;BE;DK;DE;CH;UK;NL";;1;0;0;1;0;0 215274;794618;evoDISFOLD;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Decoding Coupled Folding and Binding via Single-Molecule characterization of Ancient IDP protein-protein Interactions;2019-09-01;2021-08-31;;"Intrinsically Disordered Proteins (IDPs) are characterized by their inability to spontaneously fold into a defined 3D structure. Nonetheless, many IDPs are able to undergo disorder-to-order transitions upon binding to interaction partners, in a process known as coupled folding and binding. Although different mechanisms have attempted to rationalize this process, technical limitations have prevented from deciphering the underlying principles of coupled folding and binding. Here, I will tackle this biological problem by introducing a novel, highly interdisciplinary approach integrating, for the first time, optical tweezers (OT) and single-molecule FRET (smFRET) to resolve the microscopic steps in coupled folding and binding; and Ancestral Sequence Reconstruction (ASR) as a rational strategy to guide protein engineering. For this purpose, I will study the nuclear co-activator binding domain (NCBD) and its multiple polypeptide binding partners (both intrinsically disordered and structured) as a model to resurrect, using customized ASR methods, the sequences of interacting pairs at multiple divergence nodes along a wide evolutionary scale. Then, I will characterize their intermolecular binding and intramolecular conformational dynamics with OT/smFRET. This cutting-edge project will result in the determination of mutational trajectories defining i) the emergence of coupled folding and binding, ii) the evolution of this process, and iii) the impact of promiscuous binding to multiple partners on its evolution. This data will allow to extract the essential determinants of coupled folding and binding.";175419,6;175419,6;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;UNIVERSITAT ZURICH;CH;;;;1;0;0;1;0;0 209992;752898;ELECTROQUANTUM-2D;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Atomistic Electrodynamics-Quantum Mechanical Framework for Characterizing, Manipulating and Optimizing Nonlinear Optical Processes in 2D Materials;2018-01-15;2020-01-14;;"Two-dimensional (2D) materials, which include graphene, phosphorene, and transition metal dichalcogenides monolayers, exhibit extraordinary linear and nonlinear optical properties not attainable in bulk media. They find tremendous potentials in many photonic and optoelectronic applications, such as all-optical signal processing, optical amplification, nonlinear switching, optical microscopy, quantum detection, and sensing. The availability of first-principle, fast, efficient computer codes is a prerequisite to the bottom-up design of 2D materials. However, theoretical modeling of 2D materials faces great challenges as it needs to incorporate effects of finite size, edge truncation, periodic modulation, nonlocal, and quantum confinement. Here, we aim at developing atomistic electrodynamics-quantum mechanical theoretical models and implementing them in high-performance computing (HPC) software for characterizing, manipulating, and optimizing nonlinear optical processes (NOP) in 2D materials. The main objectives of this ambitious project are: (1) To develop a macroscopic electrodynamics approach for simulating NOP in 2D materials. (2) To develop an atomistic electrodynamics quantum mechanical framework for modeling NOP in 2D materials and compare the atomistic model to the macroscopic approach. (3) To develop user-friendly and reliable HPC software that seamlessly integrates and implements the theoretical models. (4) Using the software and theoretical models, emerging applications of 2D materials will be investigated, including solar cells, nonlinear microscopy, and biosensing. The project will have high impacts on: (1) advances in the science, technology, and industry of UK and Europe; (2) applicant’s future career development; (3) research, industrial, and transferrable knowledge exchange between the host and applicant; (4) design and commercialization of 2D material enabled devices; (5) training of students and researchers in several interdisciplinary disciplines.";183454,8;183454,8;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;UNIVERSITY COLLEGE LONDON;UK;;;;1;0;0;1;0;0 203360;678652;GrInflaGal;SIGNED;H2020-EU.1.1.;ERC-StG-2015;H2020;Gravity, Inflation, and Galaxies: Fundamental Physics with Large-Scale Structure;2016-09-01;2021-08-31;;Over the past two decades, a data-driven revolution has occurred in our understanding of the origin and evolution of our Universe and the structure within it. During this period, cosmology has evolved from a speculative branch of theoretical physics into precision science at the intersection of gravity, particle- and astrophysics. Despite all we have learned, we still do not understand why the Universe accelerates, and how the structure in the Universe originated. Recent breakthrough research, with leading contributions by the PI of this proposal, has shown that we can make progress on these questions using observations of the large-scale structure and its tracers, galaxies. This opens up a fascinating, new interdisciplinary research field: probing Gravity and Inflation with Galaxies. The goal of the proposed research is to first, probe our theory of gravity, General Relativity, on cosmological scales. Second, it aims to shed light on the origin of the initial seed fluctuations out of which all structure in the Universe formed, by constraining the physics and energy scale of inflation. While seemingly unrelated, the main challenge in both research directions consists in understanding the nonlinear physics of structure formation, which is dominated by gravity on scales larger than a few Mpc. By making progress in this understanding, we can unlock a rich trove of information on fundamental physics from large-scale structure. The research goals will be pursued on all three fronts of analytical theory, numerical simulations, and confrontation with data. With space missions, such as Planck and Euclid, as well as ground-based surveys delivering data sets of unprecedented size and quality at this very moment, the proposed research is especially timely. It will make key contributions towards maximizing the science output of these experiments, deepen our understanding of the laws of physics, and uncover our cosmological origins.;1330625;1330625;ERC-2015-STG;/ERC-STG;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;DE;;;;1;0;0;1;0;0 215497;796927;ARC-for-CORE;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Artificial Compartment for Coenzyme Regeneration;2019-03-18;2021-03-17;;This project is to build an artificial compartment for coenzyme regeneration, urgently demanded by industry and scientific research to enhance the stoichiometric use of coenzyme in biosynthetic pathways. The fellow will investigate all-round aspects of the bio-inspired system, including compartmentalization process, mass transfer and biological reactivity. A new mechanism for selective bidirectional transport and structure-reinforced composite shell will be proposed. Capitalizing upon his expertise in biomimetic controlled delivery system, carbon nanomaterial, emulsion and scanning electrochemistry, the fellowship makes him a unique asset to EU for the brand-new exploration of bio-inspired selective transport system and coenzyme regeneration compartment. The fellow has proven track record with multi- and interdisciplinary background and his achievement has been outstanding as demonstrated in CV. The skills he will gain allow him to diversify his capability significantly, including interfacial polymerization and molecular imprinting technique, visualized delivery dynamics, capsule manipulation and stability test, enzymatic integrity and activity test, compartmentalized enzymatic reaction, microfluidic multiple emulsification and techniques for SECM set-ups and analysis. The output will be the knowledge obtained from the formation of the artificial compartment through bulk and microfluidic interfacial polymerization, the compartmentalized enzymatic reactions and new set-ups for SECM. In addition, the fellowship will allow him to transfer his existing knowledge and the one emerged from the research to the hosts and a variety of audience, via complementary activities. The effective and reliable coenzyme regeneration system will address the challenge of coenzyme utilization in the biological industry. Fostered by the fellowship, a leading expert in biomimicry and coenzyme regeneration is expected to contribute greatly to EU industries and academic communities.;171460,8;171460,8;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;DE;;;;1;0;0;1;0;0 212769;758877;ORGANOMICS;SIGNED;H2020-EU.1.1.;ERC-2017-STG;H2020;Reconstructing human cortex development and malformation with single-cell transcriptomics;2018-01-01;2022-12-31;;"Technologies to sequence single-cell transcriptomes (scRNA-seq) are revolutionizing our ability to analyze cell composition and differentiation in complex tissues. In parallel, recent innovations allow the generation of three-dimensional tissues from stem cells that recapitulate human development. In this proposal, we will focus on human cortex development modelled by cerebral organoids. Our vision is to create an integrative single-cell transcriptomic platform to reconstruct cerebral organoid development, and dissect network alterations that lead to human brain malformations. Our project will be advanced through the following objectives: 1. Single-cell transcriptome-coupled lineage tracing: We will use cellular barcoding to label individual cortical progenitor cells, trace their output and lineage trees with high-throughput scRNA-seq, and quantify lineage transition probabilities between cell types. 2. Gene knockout screens in mosaic organoids: We will use CRISPR/Cas9 to perform genetic screens of up to 100 genotypes in mosaic organoids to understand mechanisms that regulate cell lineage decisions during cortex development. 3. High-throughput reconstructions of cortex malformations: We will generate cerebral organoids from patients with cortical malformations and reconstruct networks and infer differentiation hierarchies using high-throughput and lineage-coupled scRNA-seq. We will spatially resolve network aberrations using sequential fluorescence in situ hybridization (seqFISH). ORGANOMICS provides an entirely new quantitative direction to study human corticogenesis. We will build high-resolution models of cortex development by measuring the expression and function of genes in thousands of single cells. Our interdisciplinary project will lead to groundbreaking insight into mechanisms underlying neurodevelopmental diseases. Our general strategy can be extended to various other organ systems where protocols to generate in vitro counterparts can be established.";1500000;1500000;ERC-2017-STG;/ERC-STG;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;DE;;;;1;0;0;1;0;0 215620;798196;MOFdynamics;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Investigating metal-organic frameworks using excited-state dynamics and theoretical spectroscopy;2018-09-01;2021-03-02;;"The success of metal-organic frameworks (MOFs) is rooted in their structural flexibility enabling limitless possibilities for topology design and applicability. An exhaustive synthesis for potential candidate screening is however tedious and inefficient with regard to material consumption and human resources. Theoretical approaches have thus become indispensable for the simulation and prediction of electronic and structural properties. With the project 'MOFdynamics', we will make a contribution to theoretical structure modeling which will complement experimental research on MOF design. Our proposed computational approach will enable to perform excited-state molecular dynamics simulations and to calculate X-ray absorption as well as fluorescence spectra for solid-state materials, in particular MOFs. Its innovative capacity and the anticipated impact originate from combining the essential ingredients for efficient structure modeling: The treatment of the porous solids is based on periodic boundary conditions. Density functional theory in combination with hybrid functionals is employed for the description of excited states representing the most adequate electronic-structure model. Large-scale applications are made feasible by exploiting advanced computational and technical procedures for high-performance computing. To this concern, the novel developments will be implemented in the CP2K program package and applied for efficient structural characterization and analysis of experimentally synthesized MOFs. 'MOFdynamics' will advance computational tools for state-of-the-art research within the interdisciplinary field of quantum chemistry, solid-state physics and materials science. Its contributions will pave the way for a comprehensive theoretical treatment of recent progress in X-ray spectroscopy. Being implemented in a freely available software package, the proposed research represents a significant added value to the community and European excellence.";187419,6;187419,6;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;UNIVERSITAT ZURICH;CH;;;;1;0;0;1;0;0 204093;676904;NanoSCAN;SIGNED;H2020-EU.1.1.;ERC-StG-2015;H2020;Developing multi-modality nanomedicines for targeted annotation of oncogenic signaling pathways;2016-09-01;2021-08-31;;Spatial and temporal changes in the underlying biochemistry of cancer control disease progression and response/resistance to treatment. Developing methods to detect changes in oncogenic signaling at an early stage is vital to further our understanding of cancer, and will advance the next generation of anti-cancer therapies. Nanomedicine is the medical application of nanotechnology to diagnose or treat disease. In light of the recent introduction of tools like Positron Emission Tomography/Magnetic Resonance Imaging (PET/MRI) scanners, there is now a new opportunity to develop hybrid imaging protocols that can simultaneously take advantage of the functional and anatomic information available from PET/MRI to address changes in oncogenic signaling pathways. The work outlined in this interdisciplinary ERC Project is designed to advance new chemistry and imaging methods to measure changes in oncogenic signaling in various cancers before, during and after treatment using PET/MRI. The long-term goals are to expand the scope and utility of radiolabelled nanomedicines as dual-modality PET/MRI probes for detecting changes in oncogenic signaling in various cancers and develop efficient methods for translating new technologies to the clinic. Successful completion of this ERC Project has the potential to transform personalised clinical management of cancer patients via advanced PET/MRI detection of oncogenic signaling processes.;1700000;1700000;ERC-2015-STG;/ERC-STG;UNIVERSITAT ZURICH;CH;;;;1;0;0;1;0;0 198115;680901;spim4You;SIGNED;H2020-EU.1.1.;ERC-PoC-2015;H2020;spim4You: customised solutions for light sheet microscopes and imaging data analysis.;2015-11-01;2017-04-30;;"Biological research heavily relies on visualization of biological samples by microscopy. In recent years light-sheet microscopy has emerged as a paradigm shifting technique. Only with light sheet microscopy it is for instance possible to follow every cell in a living system throughout development, to monitor brain activity of a live animal or to study cancer cells in their native three dimensional environment within an organism. Thus, light sheet microscopy has the potential to revolutionize biological research and in the near future every research establishment will have a light sheet microscope. During the Hourglass ERC grant, my laboratory developed two widely used open access solutions for light sheet microscopy: 1.) OpenSPIM, a modular open hardware platform that enables anyone to construct and operate a simple light sheet microscope and 2.) a powerful library of open source software solutions to process and analyze lights sheet microscopy data. Together, these tools form a powerful foundation for exploiting the spectacular benefits of light sheet microscopy for research. The problem is however that in order to use light sheet microscopy a formidable set of expertise spanning physics, engineering, computer science and biology is required and only very few research laboratories have this level of interdisciplinary skills. The idea of our Proof of Concept proposal is to leverage the unique know-how of my laboratory generated during the ERC funding period and establish a company that will offer biology researchers assistance with all aspects of light sheet microcopy from hardware, through operation to computational data analysis. We plan to establish an expandable light sheet microscopy service - spim4You – at a time when this powerful technique enters the research mainstream and was named Method of the Year by Nature Methods.";148613;148613;ERC-2015-PoC;/ERC-POC;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;DE;;;;1;0;0;1;0;0 205552;721559;AVA;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2016;H2020;Accelerators Validating Antimatter physics;2017-01-01;2020-12-31;;"Antiprotons, stored and cooled at low energies in a storage ring or at rest in traps, are highly desirable for the investigation of basic questions on fundamental interactions, the static structure of antiprotonic atoms, CPT tests by high-resolution spectroscopy on antihydrogen, as well as gravity experiments. Antimatter experiments are at the cutting edge of science. They are, however, very difficult to realize and have been limited by the performance of the only existing facility in the world, the Antiproton Decelerator (AD) at CERN. The Extra Low Energy Antiproton ring (ELENA) will be a critical upgrade to this unique facility and commissioned from summer 2016. This will significantly enhance the beam quality and enable new experiments. To fully exploit the discovery potential of this facility and to pave the way for a vibrant long-term physics program with low energy antiprotons, advances are urgently required in numerical tools that can adequately model beam transport, life time and interaction, beam diagnostics tools and detectors that can fully characterize the beam’s properties, as well as in into advanced experimental techniques for improved precision and novel experiments that exploit the enhanced beam quality that ELENA will provide. AVA is a new European training network between universities, research centers and industry that will carry out an interdisciplinary and cross-sector antimatter research and training program for a cohort of 15 Fellows. It targets new scientific and technical developments and aims at boosting the career prospects of all trainees.";3848975,64;3848975,64;H2020-MSCA-ITN-2016;/MSCA-ITN-ETN;THE UNIVERSITY OF LIVERPOOL;UK;"COSYLAB LABORATORIJ ZA KONTROLNE SISTEME DD;THE UNIVERSITY OF MANCHESTER;FORSCHUNGSZENTRUM JULICH GMBH;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;FOTON SRO;GSI HELMHOLTZZENTRUM FUER SCHWERIONENFORSCHUNG GMBH;STAHL STEFAN;EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH;OESTERREICHISCHE AKADEMIE DER WISSENSCHAFTEN;CIVIDEC INSTRUMENTATION GMBH";"SI;UK;DE;CZ;CH;AT";;1;0;0;1;0;0 197874;648718;ARTECHNE;SIGNED;H2020-EU.1.1.;ERC-CoG-2014;H2020;Technique in the Arts. Concepts, Practices, Expertise (1500-1950);2015-09-01;2020-08-31;http://artechne.wp.hum.uu.nl/;The transmission of ‘technique’ in art has been a conspicuous ‘black box’ resisting analysis. The tools of the humanities used to study the transmission of ideas and concepts are insufficient when it comes to understanding the transmission of something as non-propositional and non-verbal as ‘technique’. The insights of the neurosciences in, for example, the acquisition and transmission of drawing skills are not yet sufficiently advanced to be historically restrictive. However, only in the most recent years, the history of science and technology has turned to how-to instructions as given in recipes. This project proposes to undertake the experimental reconstruction of historical recipes to finally open the black box of the transmission of technique in the visual and decorative arts. Considering ‘technique’ as a textual, material and social practice, this project will write a long-term history of the theory and practice of the study of ‘technique’ in the visual and decorative arts between 1500 and 1950. The three central research questions here are: (1) what is technique in the visual and decorative arts, (2) how is technique transmitted and studied, and (3) who is considered expert in technique, and why? This project will make a breakthrough in our understanding of the transmission of technique in the arts by integrating methodologies typical for the humanities and historical disciplines with laboratory work. Also, by providing a history of technique in the arts, this project lays the historical foundations of the epistemologies of conservation, restoration and technical art history precisely at a moment of greatest urgency. The connection between the history of science and technology and the expertise in conservation, restoration and technical art history (in the Ateliergebouw in Amsterdam) this project envisions builds the intellectual infrastructure of a new field of interdisciplinary research, unique in Europe.;1907944;1907944;ERC-2014-CoG;/ERC-COG;UNIVERSITEIT UTRECHT;NL;UNIVERSITEIT VAN AMSTERDAM;NL;;1;0;0;1;0;0 198652;654927;PALMOBI;CLOSED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Early Upper Palaeolithic mobility and technological decision-making under changing environmental constraints: case studies from Belgium and Romania;2016-01-01;2017-12-31;;The PALMOBI project investigates Early Upper Palaeolithic (EUP) hunter-gatherer interactions with their environment at micro- and macro-regional scales under variable ecological conditions through the integrative use of cutting-edge interdisciplinary methodologies and their application to the archaeological record of the Aurignacian and the Gravettian across two contrasting regions (temperate Belgium & continental Romania). A comparison of these two regions by applying state-of-the-art stone tool technology and raw material economy analyses, geochemical sourcing and GIS geospatial techniques in tandem with anthropological methods and theories derived from the human behavioural ecology and social agency has never previously been attempted. While continental European Palaeolithic research is mainly concerned with origins, technological lineages, and culture history, the project, by drawing on the training provided in Cambridge, will contribute to developing an innovative framework to assess EUP hunter-gatherer mobility strategies and technological decision-making, hence adaptability, in the face of variable palaeoenvironmental constraints. Besides helping understand the mechanisms underlying variability in Aurignacian and Gravettian techno-economic systems, the methodological advances resulting from this project concern the resilience of technological behaviour in the face of climate change and the role of mobility in promoting social change, and will be applicable to any period and context in the prehistory of Europe and further afield.;183454,8;183454,8;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;UK;;;;1;0;0;1;0;0 196096;661431;RE-DEV;CLOSED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Assessing the transition to renewable energy in Rapidly Developing Countries;2015-11-06;2017-11-05;;CO2 emissions are growing extremely fast in Rapidly Developing Countries, which will account for 99% of the global emissions increase by 2035 (BP 2014). Energy demand is set to increase by 75% by 2035 and (if no change incurs) will largely depend on fossil fuels (IEA 2013). In response to these concerns, Rapidly Developing Countries are currently seeking to tap its vast renewable energy potential (IRENA 2013). This shift to renewable energy provides a unique opportunity to study socio-technical transition to low-carbon technologies. Transitioning to renewable energy requires policy reform, infrastructure investment, citizen mobilization, and smart financing mechanisms. The RE-DEV project will examine the conditions for the take-up of renewable energy in Rapidly Developing Countries and, by doing so, uncover its consequences in terms of global CO2 emissions. Drawing on a comparative study of four selected country-cases (China, India, South Africa, and Morocco), this project will offer an in-depth analysis of: (a) regulatory frameworks and existing financing mechanisms, (b) the limits and potential of multilateral climate cooperation, (c) the state of vertical/horizontal transfer of know-how. The country sample responds to a most-dissimilar-systems research design. To gather evidence, this project will employ the following methods: semi-structured interviews with policy makers, questionnaires and a participatory assessment with public/private stakeholders. As a result of this, the RE-DEV project will build knowledge on how to facilitate a sustained transition to renewable energy in Rapidly Developing Countries. I put a strong emphasis on three aspects: the interdisciplinary character of the project, its intersectoral nature, and the crucial issue of its timing – it needs to be carried out now, when domestic energy transitions and the post-Kyoto climate change deal (due at Paris COP 21) are at a crucial point of their development.;158121,6;158121,6;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;Centre for International Information and Documentation in Barcelona;ES;;;;1;0;0;1;0;0 195874;660028;ExTRyG;CLOSED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Excitonic transport in cold Rydberg gases;2015-11-01;2017-10-31;;"The study of transport phenomenon based on quantum processes, where energy and information are transported but neither charge nor mass, is a vivid and interdisciplinary field of research raising both fundamental and technological issues. During this fellowship, we propose to use laser-cooled ensembles of atoms in highly excited states (cold Rydberg gases) to study such transport phenomenon. The overall purpose of the action is to demonstrate that cold Rydberg gases can be used as an innovative, efficient research platform which would allow to further address fundamental challenges related to the transport of energy and information.\\ The principal objective of this project is to form a chain of Rydberg atoms, to locally place an additional electronic excitation (exciton) in the chain and to observe the subsequent transport dynamics. A second objective is to implement adiabatic excitation of collective Rydberg excitations in order to prepare deterministically a Rydberg chain. This project will be implemented in a world leading group in cold Rydberg gases where the applicant will use two complementary experimental setups to address the different aspect of the objectives in the best conditions. He will be supervised by their respective principal investigators which will provide a strong management structure to the project. Building around the applicant's experience in the field of cold Rydberg gases, this fellowship will provide him with new, cutting-edge experimental skills which would establish him as a leading researcher in this field. The innovative, high quality research which will be carried out during this fellowship will serve as a basis for the application to a permanent position.";183454,8;183454,8;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;UNIVERSITY OF DURHAM;UK;;;;1;0;0;1;0;0 195297;656676;FEAT;CLOSED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;The role of Fluid pressure in EArthquake Triggering;2015-12-01;2017-11-30;;"Fluid overpressure has been proposed as one of the primary mechanisms that facilitate earthquake slip along tectonic faults. However, elastic dislocation theory combined with friction laws suggests that fluid overpressure may inhibit the dynamic instabilities that result in earthquakes. This controversy poses a serious problem in our understanding of earthquake physics, with severe implications for both natural and human-induced seismic hazard. Nevertheless, currently, there are only a few systematic studies of the role of fluid pressure under controlled, laboratory conditions for which the evolution of friction parameters and slip stability can be deduced. Here I propose a comprehensive experimental study of The role of Fluid pressure in EArthquake Triggering (FEAT). The proposed work will document the evolution of fault friction parameters as a function of fluid overpressure using a world-class rock deformation apparatus. The laboratory experiments will build on the characterization of fault zone structure, fluid flow, and deformation processes, which I intend to reconstruct from careful field evaluations of ancient faults that represent exhumed analogues of seismically active structures. An important part of my work will be the interaction with the energy industry to investigate the role of fluids in induced seismicity. The experimental work will strengthen my expertise in frictional and fluid flow characterisation of fault rocks. Additionally, I will develop new skills in electronic and mechanical engineering aspects of experiments. Field and microstructural work will widen my background in the field of structural geology, microstructural analysis and model construction using energy-industry software. These training-through-research activities will allow for the creation of unprecedented insight into the role of fluid pressure in earthquake triggering while broadening my competences via interdisciplinary studies and inter-sectorial experience.";180277,2;180277,2;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;UNIVERSITA DEGLI STUDI DI ROMA LA SAPIENZA;IT;;;;1;0;0;1;0;0 219752;804051;LO-ACT;SIGNED;H2020-EU.1.1.;ERC-2018-STG;H2020;Low Carbon Action in Ordinary Cities;2019-02-01;2024-01-31;;"The challenge of LO-ACT is to enable low carbon urban development in medium and small cities in rapidly urbanising areas in East, Central and West Africa, South Asia and South East Asia. The majority of emissions in the next century will be emitted by infrastructures that are yet to be built, particularly in rapidly urbanising areas where infrastructure is lacking. Population forecasts suggest that most population growth will take place in small and medium cities. Yet, to date, research on climate action has focused on showcasing strongly branded, successful initiatives in global cities. The low carbon transition depends on myriad of actions in ordinary cities, that is, cities outside global networks of climate innovation and leadership. LO-ACT will address this critical gap by delivering the first multi-dimensional, large scale assessment of low carbon action in ordinary cities. It will contribute a new framework to understand global environmental politics and urban governance. First, LO-ACT will analyse the imaginaries of local action that have shaped global environmental politics over 30 years (Objective 1). The work programme will also analyse the mobility of low carbon urban policies in transport, energy, and housing across different urban contexts (Objective 2). LO-ACT will deliver a comparative analysis of urban trajectories in 113 ordinary cities, and five in-depth ethnographic case studies (Objective 3). Finally, it will provide a critical assessment of governance theory and a revised framework to acknowledge the messy and ordinary contexts of urban action (Objective 4). LO-ACT will bring together an interdisciplinary, international team of researchers, an international network of academic advisors, and four regional hubs that will support context-specific data collection and analysis. The research will contribute to the fields of human geography, urban studies, environmental politics, sustainability transitions and science and technology studies.";1393979;1393979;ERC-2018-STG;/ERC-STG;THE UNIVERSITY OF SHEFFIELD;UK;"UNIVERSITEIT UTRECHT;UNIVERSITY COLLEGE LONDON";"NL;UK";;1;0;0;1;0;0 219722;804003;RIVERS;SIGNED;H2020-EU.1.1.;ERC-2018-STG;H2020;Water/human rights beyond the human?Indigenous water ontologies, plurilegal encounters and interlegal translation;2019-05-01;2024-04-30;;"RIVERS’s main challenge is to produce ground-breaking knowledge, from an empirical, interdisciplinary and dialoguing perspective, about the contentions and challenges intrinsic to reconceptualising human rights with different ways of understanding and relating to water. Worldwide, indigenous peoples are mobilising against the neoliberalisation of nature, demonstrating radically different ways of knowing, being and living. At the same time, in 2010 the UN acknowledged water as a human right, while in 2017 New Zealand, India and Colombia established ground-breaking legal precedents by granting rivers human rights. RIVERS’s overarching research question is: To what extent can international human rights law come to grips with plurilegal water realities? This project engages with one of the most pressing questions of this century: the relationship between humans and nature. RIVERS tackles two intertwined core objectives: 1) analysing different ways of knowing and relating to water and life among indigenous peoples and their understanding of its (potential) violation by extractive projects; 2) discussing the contributions, challenges and pitfalls of interlegal translation of differing water natures in plurilegal encounters at domestic and international levels. RIVERS will develop a multi-sited analysis and empirical case-studies in three contexts: Colombia, Nepal and the UN human rights protection system. Through the lens of legal pluralism, this will foreground competing political and legal water realities that interrogate dominant understandings of the modern world. RIVERS will address two interrelated research challenges: 1) indigenous visions/practices: beyond water as a natural resource and human right; 2) the UN human rights system: towards counter-hegemonic water knowledge production. This project will pioneer new ways of thinking about water beyond the modern divides of nature/culture, providing clues about future paths towards reconceptualising human rights.";1498446;1498446;ERC-2018-STG;/ERC-STG;UNIVERSIDAD DE LA IGLESIA DE DEUSTO ENTIDAD RELIGIOSA;ES;;;;1;0;0;1;0;0 219976;804985;Digital Good;SIGNED;H2020-EU.1.1.;ERC-2018-STG;H2020;The Digital Disruption of Health Research and the Common Good. An Empirical-Philosophical Study;2019-01-01;2023-12-31;;"In the last three years, every major consumer technology company has moved into the health research domain. We are witnessing a digital disruption of health research, or a “Googlization of health research” (GHR). This project will be the first wide-ranging, interdisciplinary study of GHR. Its aim is to develop a normative framework for personal health data governance in this setting, where digital health and digital capitalism, and codes of research ethics and the lawlessness of the Internet economy, intersect. I contend that the most pressing challenge at stake in this new model of research is less the question of individual privacy than the question of collective and societal welfare, and that existing governance frameworks that seek to increase individual control over data are ill-suited to address this. Commons- and solidarity-based approaches, which seek to enhance collective agency and control, are thus promising alternatives. However, these approaches allow for only one conception of the common good, while a plurality of competing conceptions are at work in GHR, including “increased efficiency”, “greater inclusivity”, and “economic growth”. This plurality must be taken seriously to avoid theory-practice discrepancies and to develop viable governance solutions. The project will develop a normative framework that can both foreground collective benefit all the while accounting for this ethical plurality. To do this, my team will first map the different conceptions of the common good – or “moral repertoires” – that motivate actors in several GHR-type collaborations. Using an empirical-philosophical methodology, we will critically evaluate these repertoires and the value trade-offs they involve in practice. Next, we will explore the viability of commons- and solidarity-based approaches in light of this. Finally, these results will be integrated into a novel, empirically-robust normative framework that can offer guidance to research ethicists and policy makers.";1323473;1323473;ERC-2018-STG;/ERC-STG;STICHTING KATHOLIEKE UNIVERSITEIT;NL;;;;1;0;0;1;0;0 219727;804286;UNISCAMP;SIGNED;H2020-EU.1.1.;ERC-2018-STG;H2020;The unity of scattering amplitudes: gauge theory, gravity, strings and number theory;2019-01-01;2023-12-31;;"Scattering amplitudes are central observables in quantum field theory and provide essential information about the quantum consistency of perturbative gravity. Precise control of the physical and mathematical properties of scattering amplitudes holds the key to long-standing questions on fundamental interactions and the structure of space and time. As a concrete leap in this direction, UNISCAMP addresses predictions in gauge theories, gravity and effective theories through - the efficient computation and compact representation of scattering amplitudes and, - decoding their hidden structures & symmetries and their rich web of connections. String-theory methods will complement conventional approaches to scattering amplitudes, and I will combine the insights from - the point-particle limit of superstrings & heterotic strings and, - the recent ambitwistor strings which directly compute field-theory amplitudes. Both of them naturally incorporate the double-copy relation between gauge-theory & gravity amplitudes and extend the framework to effective field theories describing pions and other low-energy states. It is a primary goal of UNISCAMP to pinpoint the unifying principles connecting a wide range of field and string theories. My expertise in both flavours of string theories will allow to optimally exploit their fruitful synergies and to depart from mainstream approaches. Moreover, field- and string-theory amplitudes exhibit an intriguing mathematical structure: Their Feynman- and moduli-space integrals yield special functions such as polylogarithms which became a vibrant common theme of high-energy physics and number theory. As an interdisciplinary goal of UNISCAMP, I will - investigate the low-energy expansion of multiloop string amplitudes and, - extract an organizing scheme for iterated integrals on higher-genus Riemann surfaces. These research objectives should benefit from my experience in collaborations with mathematicians.";1425000;1425000;ERC-2018-STG;/ERC-STG;UPPSALA UNIVERSITET;SE;;;;1;0;0;1;0;0 219749;794595;TOKUGAWATRAVEL;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Travel in Tokugawa Period Japan (1603-1868): Identity, Nationand Social Transformation;2019-04-01;2021-03-31;;"This research project investigates the practice of travel in Edo/Tokugawa Japan (1603-1868), particularly in connection with notions of social identity, transformation, and nationhood. Through a theoretical framework that combines Social History and Historical Bibliography, primary sources will be investigated, including commercially “unofficial” and “popular” sources published and distributed, such as travel guides and commercial maps. In the analysis the material will be considered: a) as objects, viewed in the light of the cultural and economical processes that led to their production and circulation, in order to understand the “range” of the ideological impact of travel; and b) in terms of their contents, in order to assess how their “commercialized” narratives reflect popular notions of identity and nationhood. An interdisciplinary approach, based on Travel Studies, Japanese Historiography, and in particularly, World Society Theory, will be implemented to discuss the cultural and social meaningof travel in the context of Tokugawa “absolutism”. Travel tends to be entwined with social mobility, in a way that alters and marks social and cultural landscapes. The project will therefore investigate whether travel within Japan, becoming growingly commonin a context of economic growth, came to subvert the geographical and social immobility that characterized Tokugawa administrative system. Furthermore, the analysis will discuss the relationship between travel and the formation of a national identity, assessing whether the social and ideological transformation connected with travel worked in Japan as a prompt for “proto-national” identification,as opposed to forms of local nationalism.";183454,8;183454,8;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;THE UNIVERSITY OF MANCHESTER;UK;;;;1;0;0;1;0;0 219709;802512;COSMOLOCALISM;SIGNED;H2020-EU.1.1.;ERC-2018-STG;H2020;Design Global, Manufacture Local: Assessing the Practices, Innovation, and Sustainability Potential of an Emerging Mode of Production;2019-01-01;2022-12-31;;"COSMOLOCALISM will document, analyse, test, evaluate, and create awareness about an emerging mode of production, based on the confluence of the digital commons (e.g. open knowledge and design) with local manufacturing and automation technologies (from 3D printing and CNC machines to low-tech tools and crafts). This convergence could catalyse the transition to new inclusive and circular productive models, such as the “design global, manufacture local” (DGML) model. DGML describes the processes through which design is developed as a global digital commons, whereas the manufacturing takes place locally, through shared infrastructures and with local biophysical conditions in mind. DGML seems to form economies of scope that promote sustainability and open innovation while celebrating new ways of cooperation. However, such claims rest on thin conceptual and empirical foundations. COSMOLOCALISM is a multiphase, pilot-driven investigation of the DGML phenomenon that seeks to understand relevant organisational models, their evolution, and their broader political economy/ecology and policy implications. Through the lens of diverse case studies and participatory action research, the conditions under which the DGML model thrives will be explored. COSMOLOCALISM has three concurrent streams: practices; innovation; and sustainability. First, DGML practices will be studied, patterns will be recognised and their form, function, cultural values, and governance structure will be determined. Second, the relevant open innovation ecosystems and their potential to reorient design and manufacturing practices will be examined. Third, selected DGML products will be evaluated from an environmental sustainability perspective, involving both qualitative and quantitative methods. The interdisciplinary nature of COSMOLOCALISM will explore new horizons to substantively improve our understanding of how we could do “more” and “better” with less.";1017275;1017275;ERC-2018-STG;/ERC-STG;TALLINNA TEHNIKAULIKOOL;EE;;;;1;0;0;1;0;0 194414;646122;MACIVIVA;SIGNED;H2020-EU.2.1.2.1.;NMP-08-2014;H2020;MAnufacturing process for Cold-chain Independent VIrosome-based VAccines;2015-05-04;2018-11-03;;"MACIVIVA is a highly interdisciplinary consortium among well established and innovative SMEs with scientific excellence and complementary industrial world-leading experts with unique expertise and know-how in virosome technology, spray and freeze drying, large scale manufacturing and packaging. MACIVIVA will pave the path to other large scale thermostable nanopharmaceuticals products for therapeutic and prophylactic vaccines and other potential applications for direct application by non-invasive routes. Liquid products are inherently prone to physical and/or chemical modifications and degradations. Solid vaccine dosage formats (e.g. powder) may prevent molecular motion and shear-induced degradation, and slow down degradation involving water and oxygen radicals, resulting in improved stability and enhanced shelf-life of vaccines. The cold chain storage is still fundamental for preserving the bioactivity of most liquid and freeze-dried vaccines, and a reconstitution step prior to administration is required for freeze dried vaccines that are usually administered intramuscularly or subcutaneously. These reconstituted freeze dried vaccines harbor important instability and must be used within hours and kept refrigerated. Because most liquid and reconstituted freeze-dried vaccines are susceptible to degradations, it may affect the immunological properties of the immunogens, with unwanted immune responses or insufficient immune protection. For addressing liquid virosome-based vaccine instability and improving their shelf-life outside the cold chain, MACIVIVA will explore new galenic vaccine formulations through careful screening of excipients, stabilization and drying methods for generating new vaccine solid forms that can be easily self-administered. Robust “universal” manufacturing processes for upscale production of virosome dried powder for the non-invasive intranasal, oral and sublingual routes should be achieved by month 42.";8438905,63;5338886,88;H2020-NMP-PILOTS-2014;/RIA;MYMETICS BV;NL;"CHIMERA BIOTEC GMBH;CATALENT U.K. SWINDON ZYDIS LIMITED;BACHEM AG;MYMETICS SA;UPPERTON LIMITED";"DE;UK;CH";;1;0;0;1;0;0 194548;648763;INTERACT;SIGNED;H2020-EU.1.1.;ERC-CoG-2014;H2020;Intelligent Non-woven Textiles and Elastomeric Responsive materials by Advancing liquid Crystal Technology;2015-04-01;2020-03-31;;"A grand challenge in today’s materials research is the realization of flexible materials that are also intelligent and functional. They will be the enablers of true breakthroughs in the hot trends of soft robotics and wearable technology. The standard approach to the latter is to decorate rubber sheets with electronic components, yielding two serious flaws: rubber is uncomfortable as it does not breath and solid state electronics will eventually fail as a garment is flexed and stretched when worn. While the softness of rubber is ideal it must be used in the form of textile fibers to provide breathability, and for long-term failure resistance we need intelligent components that are soft. A solution to this conundrum was recently presented by the PI with the concept of liquid crystal (LC) electrospinning. The extreme responsiveness of LCs is transferred to a non-woven textile by incorporating the LC in the fiber core, yielding a smart flexible mat with sensory function. Moreover, it consumes no power, providing a further advantage over electronics-based approaches. In a second research line he uses microfluidics to make LC rubber microshells, functioning as autonomous actuators which may serve as innovative components for soft robotics, and photonic crystal shells. This interdisciplinary project presents an ambitious agenda to advance these new concepts to the realization of soft, stretchable intelligent materials of revolutionary character. Five specific objectives are in focus: 1) develop understanding of the dynamic response of LCs in these unconventional configurations; 2) establish interaction dynamics during polymerisation of an LC precursor; 3) elucidate LC response to gas exposure; 4) establish correlation between actuation response and internal order of curved LCE rubbers; and 5) assess usefulness of LC-functionalized fibers and polymerized LC shells, tubes and Janus particles in wearable sensors, soft robotic actuators and high-security identification tags.";1929976;1929976;ERC-2014-CoG;/ERC-COG;UNIVERSITE DU LUXEMBOURG;LU;;;;1;0;0;1;0;0 194567;649263;MOVE;SIGNED;H2020-EU.3.6.;YOUNG-2-2014;H2020;Mapping mobility – pathways, institutions and structural effects of youth mobility in Europe;2015-05-01;2018-04-30;;"The overall ambition of MOVE is to provide a research-informed contribution towards an improvement of the conditions of the mobility of young people in Europe and a reduction of the negative impacts of mobility through the identification of ways of good practice thus fostering sustainable development and wellbeing. The consortium of MOVE is built up of nine partners within six countries: Luxembourg, Germany, Hungary, Norway, Romania and Spain. The main research question is: How can the mobility of young people be ‘good’ both for socio-economic development and for individual development of young people, and what are the factors that foster/hinder such beneficial mobility? Based on an interdisciplinary and multilevel research approach the main objectives of MOVE are to: [1] carry out a comprehensive analysis of the phenomenon of mobility of young people in the EU; [2] generate systematic data about young people’s mobility patterns in Europe based on qualitative case studies, a mobility survey and on secondary data analysis; [3] provide a quantitative integrated database on European youth mobility; [4] offer a data based theoretical framework in which mobility can be reflected, thus contributing to the scientific and political debates. [5] explore factors that foster and factors that hinder good practice based on an integrative approach with qualitative and quantitative evidence. [6] provide evidence-based knowledge and recommendations for policy makers through the development of good-practice models. MOVE is based on a multilevel research design, including case studies on six types of mobility (higher education, voluntary work, employment, vocational training, pupil's exchange and entrepreneurship), a survey (N=6400) and secondary data analysis, taking into consideration social inequality (e.g. migration background, gender, educational inequalities, impairments). The focus will be on the regional contexts of mobility and the agency of young people.";2499910;2499910;H2020-YOUNG-SOCIETY-2014;/RIA;UNIVERSITE DU LUXEMBOURG;LU;"STIFTUNG UNIVERSITAT HILDESHEIM;EURICE EUROPEAN RESEARCH AND PROJECT OFFICE GMBH;MISKOLCI EGYETEM;HOGSKULEN PA VESTLANDET;ILUSTRE COLEGIO NACIONAL DE DOCTORES Y LICENCIADOS EN CIENCIAS POLITICAS Y SOCIOLOGIA;ACADEMIA DE STUDII ECONOMICE DIN BUCURESTI;DEUTSCHES JUGENDINSTITUT EV;AGENCE EUROPEENNE POUR L'INFORMATION ET LE CONSEIL DES JEUNES ASBL;HOGSKULEN I SOGN OG FJORDANE";"DE;HU;NO;ES;RO;LU";;1;0;0;1;0;0 219505;787282;B2C;SIGNED;H2020-EU.1.1.;ERC-2017-ADG;H2020;Beasts to Craft: BioCodicology as a new approach to the study of parchment manuscripts;2018-12-01;2023-11-30;;"The intention of Beasts to Craft (B2C) is to document the biological and craft records in parchment in order to reveal the entangled histories of animal improvement and parchment production in Europe from 500-1900 AD. B2C will lay the foundations for a new approach to the the study of parchment manuscripts —biocodicology— which draws evidence from the overlooked first stages in production, the raising of livestock and the preparation of the skins. 1. Parchment is an extraordinary but overlooked high resolution zooarchaeological record and a molecular archive. Livestock genetics is revealing breed diversity and markers of character traits such as fleece quality. B2C will exploit this new-found knowledge, using progressively older dated archival (sheep) parchments to study the history of improvement 1300 - 1900. Visual examination of the skins will search for direct evidence of disease and fleece quality. 2. Craft skills can be read from parchment and, when combined with chemical data and comparison with modern analogues, will produce the first European wide record of the craft from 500-1900. The size and scope of this the parchment archive means it is one of the largest and most highly resolved records of a specialist medieval craft. We will explore how these skills develop and when and where regional patterns appear and decline. These two remarkable records requires a large interdisciplinary team. However biocodicology draws from and informs upon a wide and diverse spectrum of existing scholarship in conservation, the arts and sciences. A third strand of the project will (i) furnish manuscript scholars with some of the information available to the scribe at time of production (ii) inform and shape attitudes to parchment conservation (iii) provide high resolution biological data on animal management, movement and health and (iv) explore methods to link datasets and promote data reuse.";2499462;2499462;ERC-2017-ADG;/ERC-ADG;KOBENHAVNS UNIVERSITET;DK;"THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;DET KONGELIGE BIBLIOTEK, NATIONALBIBLIOTEK OG KOBENHAVNS UNIVERSITETSBIBLIOTEK";"UK;DK";;1;0;0;1;0;0 219521;805478;MULTIPALEOIBERIA;SIGNED;H2020-EU.1.1.;ERC-2018-STG;H2020;Population dynamics and cultural adaptations of the last Neandertals and first Modern humans in inland Iberia: a multi-proxy investigation;2019-01-01;2023-12-31;;The relations between cultural developments and environmental change among hunter-gatherers are crucial for studying population dynamics during the last glaciation (110,000–11,700 years ago). However, proposing solid interpretations on how climate and environment variability affected the social and techno-economic organisation of hominins, requires robust geoarchaeological, chronological, and palaeoecological evidence. In the Iberian Peninsula, a key area for this period due to its geographic position and ecological variability, models on these topics are biased by the poor quality of available evidence for its interior lands. The Iberian interior has been traditionally depicted as a marginal and few populated region due to its harsh ecological conditions compared to the coastal areas. Based on preliminary data suggesting that this picture could be wrong, I hypothesize (1) that the human settlement of interior Iberia during this period was more stable than previously thought and (2) that his has relevant implications at the European scale for problems such as the replacement of Neandertals by modern humans, the first modern human peopling of Europe, and the patterns of land use and mobility during the coldest stages of the last glacial. To test these hypotheses, this project will investigate population dynamics and human-environment interactions of the last Neandertals and first modern humans in interior Iberia based on completely unprecedented evidence gathered by means of a macro-regional and interdisciplinary research project. This involves the participation of a wide team of scholars coordinated by the PI, and a network of methods including field surveys, geoarchaeological excavations and chronometric, paleoecological, zooarchaeological, techno-economic and symbolic studies. The results will significantly change our views on key biocultural and ecological processes of the European prehistory, and the way human societies have dealt with challenging environments.;1387515;1387515;ERC-2018-STG;/ERC-STG;UNIVERSIDAD DE ALCALA;ES;;;;1;0;0;1;0;0 219377;825225;Safe-DEED;SIGNED;H2020-EU.2.1.1.;ICT-13-2018-2019;H2020;Safe Data Enabled Economic Development;2018-12-01;2021-11-30;;As privacy and trust remain key in the data sharing debate, Privacy enhancing technologies (PET) will play a prominent role by 2025. Safe-DEED takes a highly interdisciplinary approach, bringing together partners from cryptography, data science, business innovation, and legal domain to focus on improving Security technologies, improving trust as well as on the diffusion of Privacy enhancing technologies to keep up pace with global macrotrends and the data economy, to enable the fastest possible growth. Furthermore, as it has been recently shown that even among large companies, many have no data valuation process in place, Safe-DEED provides a set of tools to facilitate the assessment of data value, thus incentivising data owners to make use of the scalable cryptographic protocols developed in Safe-DEED to create value for their companies and their clients.;2996400;2996400;H2020-ICT-2018-2;/RIA;KNOW-CENTER GMBH RESEARCH CENTER FOR DATA-DRIVEN BUSINESS & BIG DATA ANALYTICS;AT;"INFINEON TECHNOLOGIES AG;ELLINIKI ETAIRIA TILEPIKOINONION KAI TILEMATIKON EFARMOGON AE;RESEARCH STUDIOS AUSTRIA FORSCHUNGSGESELLSCHAFT MBH;FUNDACIO EURECAT;KATHOLIEKE UNIVERSITEIT LEUVEN;TECHNISCHE UNIVERSITEIT DELFT;LSTECH ESPANA SL";"DE;EL;AT;ES;BE;NL";;1;0;0;1;0;0 219479;824671;SUPER_MoRRI;SIGNED;H2020-EU.5.c.;SwafS-21-2018;H2020;Scientific Understanding and Provision of an Enhanced and Robust Monitoring system for RRI;2019-01-01;2023-12-31;;Across Europe, the need for a more dynamic governance and a better societal integration of research and innovation is increasingly appreciated. Internal drivers of change (such as the digitalization of science) and political will to better align with societal needs and concerns are bringing about aspirational policies and processes of transformation of the R&I system, including those of RRI – responsible research and innovation. In order for the aspirations of RRI to be realised, robust tools must be developed for R&I policy and practice. The MoRRI project (2014-2018) conceptualised and implemented the first RRI monitoring system in Europe. The SUPER_MoRRI project builds upon and continues the work of MoRRI, ensuring sustained data collection, curation, further assessment and refinement of the MoRRI indicators. EU-28(-27) data will be complemented by monitoring data from selected non-EU countries. Furthermore, SUPER_MoRRI will go well beyond the technical efforts of MoRRI and develop a more complete scientific understanding of the complex and diverse relationships between RRI policies and practices and their societal, democratic and economic benefits. These theoretical advances together with the continuous data stream into the project form the basis of the iterative learning processes needed to create a mature monitoring system with indicators and metrics that are robust, realistic, in themselves responsible, and easy to implement. To meet these ambitious research challenges, the original scientific partners of MoRRI have included complementary RRI expertise to form the truly interdisciplinary SUPER_MoRRI consortium. In line with the concept of RRI itself, our learning processes will also be enhanced by participatory co-creation practices with stakeholders. Last, but not least, the project includes a series of measures to facilitate dissemination of the mature monitoring system, including international benchmarking and an easy-to-customize online dashboard system.;2998820;2998820;H2020-SwafS-2018-1;/RIA;FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.;DE;"INSTITUT FUER HOEHERE STUDIEN - INSTITUTE FOR ADVANCED STUDIES;UNIVERSIDAD POMPEU FABRA;AARHUS UNIVERSITET;UNIVERSITEIT LEIDEN;AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS;SIVECO ROMANIA SA;UNIVERSITETET I BERGEN;TECHNISCHE UNIVERSITEIT DELFT";"AT;ES;DK;NL;RO;NO";;1;0;0;1;0;0 193628;639125;DE-ORPHAN;SIGNED;H2020-EU.1.1.;ERC-StG-2014;H2020;DEtermination of Orphan Receptor PHysiological Agonists and sigNals;2015-05-01;2020-04-30;;"G protein-coupled receptors make up both the largest membrane protein and drug target families. DE-ORPHAN aims to determine the close functional context; specifically physiological agonists and signaling pathways; and provide the first research tool compounds, of orphan peptide receptors. Determination of physiological agonists (aka de-orphanization), by high-throughput screening has largely failed. We will introduce a new research strategy: 1) developing highly innovative bioinformatics methods for handpicking of all orphan receptor targets and candidate ligand screening libraries; and 2) employing a screening technique that can measure all signaling pathways simultaneously. The first potent and selective pharmacological tool compounds will be identified by chemoinformatic design of focused screening libraries. We will establish the ligands’ structure-activity relationships important for biological activity and further optimization towards drugs. The first potent and selective Gs- and G12/13 protein inhibitors will be designed by structure-based re-optimization from a recent crystal structure of a Gq-inhibitor complex, and applied to determine orphan receptor signaling pathways and ligand pathway-bias. They will open up for efficient dissection of important signaling networks and development of drugs with fewer side effects. DE-ORPHANs design hypotheses are based on unique computational methods to analyze protein and ligand similarities and are founded on genomic and protein sequences, structural data and ligands. The interdisciplinary research strategy applies multiple ligands acting independently but in concert to provide complementary receptor characterization. The results will allow the research field to advance into studies of receptor functions and exploitation of druggable targets, ligands and mechanisms. Which physiological insights and therapeutic breakthroughs will we witness when these receptors find their place in human pharmacology and medicine?";1499926,25;1499926,25;ERC-2014-STG;/ERC-STG;KOBENHAVNS UNIVERSITET;DK;;;;1;0;0;1;0;0 195339;656842;HspAdhesion;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Role of cell membrane associated Hsp70 in cancer cell adhesion and metastasis;2015-05-01;2017-04-30;;We propose an interdisciplinary project at the interface of biophysics, biochemistry, and medical research. Our objective is to investigate the specific role of cell membrane associated heat shock protein 70 (Hsp70) in the context of invasive cancer. In particular we address the question how cell membrane localization of Hsp70 affects differential adhesion of cancer cells and the formation of metastasis. In general, heat shock proteins (HSP) assist in folding of nascent proteins, prevent protein aggregation, and assist transport of proteins. Upon a variety of stresses HSP production is rapidly upregulated. Hsp70 is the major stress-inducible member of the HSP70 family. In normal cells it copes with harmful unfolded and denatured protein conferring protection to the cell. Tumor cells frequently present Hsp70 on their outer surface where it exhibits additional activities. For a number of different tumors a high level of membrane Hsp70 has been found to indicate drastically decreased survival chances in patients. Moreover it has been implicated in formation of metastasis where it might support spread and anchoring into distant tissues. These findings highlight the clinical significance of cell membrane associated Hsp70 and the need for a better understanding of its role in differential cell adhesion and progression of cancer. We will employ atomic force microscopy (AFM) in order to elucidate the function of membrane Hsp70 as a possible adhesion molecule or mediator of cellular adhesion. (1) Using single-cell force spectroscopy we will characterize and quantify adhesion forces of Hsp70 positive and negative cells to different substrates mimicking their interaction with extracellular matrix and host tissue. (2) With the help of a specialized AFM technique that enables topography imaging with a simultaneous recognition of specific surface molecules we will determine the localization and arrangement of Hsp70 molecules on the cell surface with nanometer resolution.;166156,8;166156,8;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;UNIVERSITAT LINZ;AT;;;;1;0;0;1;0;0 194532;648295;GraM3;SIGNED;H2020-EU.1.1.;ERC-CoG-2014;H2020;Surface-grafted metallofullerene molecular magnets with controllable alignment of magnetic moments;2015-06-01;2020-05-31;;"The molecules retaining their magnetization in the absence of magnetic field are known as single molecule magnets (SMMs). Important problems to be solved on the way to the applications of SMMs in molecular spintronics is their deposition on surfaces and addressing their spins on the single molecular level. In this project we will address these problems by designing SMMs based on endohedral metallofullerenes (EMFs) derivatized with anchoring groups. SMM behaviour recently discovered for DySc2N@C80 and Dy2ScN@C80 in PI’s group is governed by a strong magnetic anisotropy (magnetic moments of Dy ions are aligned along the Dy–N bonds) and ferromagnetic exchange interactions between Dy ions within the clusters. Protected by the carbon cages, these SMMs exhibit uniquely long zero-field relaxation times of several hours at 2 K and provide an ideal system for addressing the individual spin states. Spatial orientation of magnetic moments in EMF-SMMs is determined by the endohedral cluster and is therefore influenced by the orientation of the EMFs molecules and their internal dynamics. We will apply three strategies to control the spatial arrangement of the magnetic moments in EMF-SMMs: (i) deposition of EMF molecules via sublimation; (ii) exohedral modification of EMFs with anchoring groups for grafting of EMFs on surfaces; (iii) introducing photoswitchable units into the anchoring groups which can reversibly change their geometry upon impact of light and will allow switching direction of the magnetic moment in a fully controllable way. Magnetic behaviour of the surface-grafted SMMs will be studied by bulk- and surface-sensitive techniques including X-ray magnetic circular dichroism and especially spin-polarized scanning tunneling microscopy. Successful fulfillment of the objectives of this interdisciplinary high-risk/high-gain project will revolutionize the field of the surface molecular magnetism by allowing the study and control of the SMMs on a single spin level.";1912181;1912181;ERC-2014-CoG;/ERC-COG;LEIBNIZ-INSTITUT FUER FESTKOERPER- UND WERKSTOFFFORSCHUNG DRESDEN E.V.;DE;;;;1;0;0;1;0;0 196708;654933;3Dconvert;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;The dynamics of the mammalian epigenome during transcription factor-induced cell fate conversion;2015-05-01;2017-04-30;;Cell fate conversion processes bear considerable therapeutic potential yet are poorly understood, and have thus remained slow, inefficient and difficult to translate into medical applications. The low conversion frequency in current systems, such as classic reprogramming to ‘induced’ pluripotent stem (iPS) cells, has precluded a molecular study of the critical early conversion events. We propose an interdisciplinary, exhaustive and unbiased approach to unravel the molecular events that accompany cell fate conversion processes, in particular during the early phase, using two uniquely efficient and controllable experimental systems. Special emphasis will be put on documenting the dynamics of three-dimensional genome topology, as this potential epigenetic conversion barrier has not yet been systemically characterized during cell fate conversions. We will apply genome-wide chromosome conformation capture and other genomic technologies on B cells undergoing nearly 100% efficient transdifferentiation into macrophages or reprogramming into iPS cells. In-depth computational analyses and dataset integration will reveal the dynamic relationships between transcription factor binding, key epigenetic regulatory mechanisms including genome topology, and the gene expression changes that ultimately lead to the implementation of a new cellular phenotype. Acquiring such insights will signify a breakthrough in our understanding of the epigenetic features that underpin cell identity and plasticity. Besides significantly advancing the state-of-the-art, the proposed action will maximize the applicant’s capacity of reaching professional maturity and scientific independence.;158121,6;158121,6;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;FUNDACIO CENTRE DE REGULACIO GENOMICA;ES;;;;1;0;0;1;0;0 219190;824017;B-LigZymes;SIGNED;H2020-EU.1.3.3.;MSCA-RISE-2018;H2020;Bacterial Enzymes and Bioprocesses for Lignin Valorisation;2019-02-01;2023-01-31;;"B-LigZymes is an international, interdisciplinary and intersectorial platform that directly addresses current limitations in lignin degradation by generating technological and economical solutions inspired by fundamental research. B-LigZymes provides a holistic view for the development of biocatalytic processes involved in the valorisation of lignin. The B-LigZymes consortium is composed of 6 academic organizations, 4 of which are located in Europe (Portugal, The Netherlands, Italy and Germany), 1 in the United States and 1 in Argentina; there are 2 non-academic organizations in the partnership located in Spain and Finland. The B-LigZymes programme foster collaborations across sectors, disciplines and countries and a shared culture of research & innovation (R&I) that welcomes and rewards creativity and entrepreneurship. The existent complementarity among Beneficiary Organizations and partners enables bi-directional international and intersectorial staff exchanges and the sharing of knowledge and ideas from research to market and vice-versa. These activities will be additionally nurtured by wide network training events, such as workshops, where the contribution of members with different expertise will bring a synergistic effect. Overall, the networking activities proposed will allow research members to develop new R&I and transferable skills that will boost future career opportunities, strengthening Europe’s human capital, competitiveness and growth and, contributing for a knowledge-based economy and society, in accordance to the expected objectives and impact of the RISE’s MSCA call.";1025800;970600;H2020-MSCA-RISE-2018;/MSCA-RISE;UNIVERSIDADE NOVA DE LISBOA;PT;"UNIVERSITA DEGLI STUDI DI ROMA TOR VERGATA;METGEN OY;TECHNISCHE UNIVERSITAET BRAUNSCHWEIG;ZYMVOL BIOMODELING SL;RIJKSUNIVERSITEIT GRONINGEN";"IT;FI;DE;ES;NL";;1;0;0;1;0;0 218991;825762;EDCMET;SIGNED;H2020-EU.3.1.1.;SC1-BHC-27-2018;H2020;Metabolic effects of Endocrine Disrupting Chemicals: novel testing METhods and adverse outcome pathways;2019-01-01;2023-12-31;;Endocrine disruptors (EDs) are defined as exogenous chemicals that alter functions of the endocrine system, thereby causing adverse health effects in an organism or its progeny. Historically, the field of ED research has focused on reproductive endocrinology and related hormones, which is reflected in the regulatory test methods assessing endocrine effects of xenobiotics. However, recent evidence links increased incidence of metabolic syndrome (a cluster of metabolic risk factors including abdominal obesity, dyslipidemia, elevated blood pressure, and elevated fasting glucose) to EDs, increasing the incidence of atherosclerosis and type 2 diabetes. Despite these findings, adequate testing methods for metabolic effects of EDs are lacking. The project “Metabolic effects of Endocrine Disrupting Chemicals: novel testing METhods and adverse outcome pathways” (EDCMET) brings together experts in various research fields, including systems toxicologists, experimental biologists with a thorough understanding of the molecular mechanisms of metabolic disease and comprehensive in vitro and in vivo methodological skills and ultimately, epidemiologists linking environmental exposure to adverse metabolic outcomes. This proposal focuses on developing novel test methods and models to assess the metabolic effects of EDs. Combined in silico methods, in vitro and in vivo methods are developed with an emphasis on liver and adipose tissue and endocrine pathways related to their metabolism. In addition, epidemiological and field monitoring data is used to gain information regarding the exposure to chemicals and ED-related metabolic effects. The interdisciplinary approach and complementary expertise of the participants will identify novel mechanisms of action, and in collaboration with the European Commission Joint Research Centre (JRC) providing an interface between the programme and European regulatory agencies, novel validated test methods for regulatory purposes will be generated.;5980408,75;5980408,75;H2020-SC1-2018-Single-Stage-RTD;/RIA;ITA-SUOMEN YLIOPISTO;FI;"BUNDESINSTITUT FUER RISIKOBEWERTUNG;OULUN YLIOPISTO;EUROSAFE;PAMGENE INTERNATIONAL BV;UNIVERSITY OF LEEDS;AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS;WAGENINGEN UNIVERSITY;UNIVERZITA KARLOVA;EBERHARD KARLS UNIVERSITAET TUEBINGEN;NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU";"DE;FI;FR;NL;UK;ES;CZ;NO";;1;0;0;1;0;0 218982;836211;BioFlex;SIGNED;"H2020-EU.3.;H2020-EU.2.3.;H2020-EU.2.1.";EIC-SMEInst-2018-2020;H2020;Second life of wood: technology to dissolve waste wood to get raw materials;2018-11-01;2019-04-30;;"We have developed the BioFlex solvent process that uses unwanted waste wood as a very cheap raw-material to produce clean and high-quality inputs for the production of renewable chemicals, fuels and materials. An inexpensive process separates the main components of wood: cellulose and lignin. These can then be turned into final products such as bio-plastics, common chemicals and novel materials. There are a variety of new value chains that are potentially created through our technology. For example, using the waste wood from a local council, cellulose can be isolated, which is hydrolysed, fermented to succinic acid and then used in paint. The lignin isolated alongside the cellulose can be turned into a drop-in biodiesel sold at the local petrol station. Similarly, sawdust from a timber mill can be fractionated, the cellulose used to produce methylcellulose as a thickener in food, the lignin turned into a bio-derived plastic. We are diverting wood waste from going to landfill or incineration and sawdust going into pellets. The European pellets market is saturated, also with pellets imported from the Americas. The lignin and cellulose produced from these currently underused wood resources can enter new, emerging, or existing value chains. Our competition on the waste wood disposal side is incineration, offering energy recovery in some cases but resulting in the formation of toxic ash and contributing to air pollution. For some heavily treated waste wood there are no competitors except for costly and highly undesirable landfilling which are largely viewed as problematic by both waste producers and waste managers. The market is estimated to be EUR 40.9 billion for BioFlex products and EUR 13.4 billion of waste wood recycling. We have established a clear timeline for commercialization and signed a number of agreements with partners to make this plan feasible. We have an interdisciplinary and dedicated team to make Bioflex and its products available on the market.";71429;50000;H2020-SMEInst-2018-2020-1;/SME-1;CHRYSALIX TECHNOLOGIES LIMITED;UK;;;;1;0;0;1;0;0 206778;737447;PHYSIC;SIGNED;H2020-EU.1.1.;ERC-PoC-2016;H2020;Photovoltaic with superior crack resistance;2017-01-01;2018-06-30;;Cracks in silicon solar cells composing photovoltaic (PV) modules are induced during production (soldering of busbars onto solar cells, other defects), transportation, installation and exposure to the environment. The economic impact of cracking in PV modules has been assessed in about 6 Euro/(kWp year) due to the cost of repair/substitution and the missing production while cracks are not yet observable with the naked eye. This has a clear huge technological and economic impact on the market that can be estimated in 180 MEuro/year of losses, by considering a conservative amount of 30 GWp of new installations in the World per year. If cracking cannot be avoided due to the brittleness of Silicon, the proposed idea to be taken to proof of concept is to limit its effect as much as possible. A new generation of PV modules displaying a superior resistance against cracking is proposed, starting from the fundamental discovery within the CA2PVM ERC StG project that residual thermo-mechanical compressive stresses in Silicon cells are beneficial to induce crack face contact and electric recovery. An innovative pre-stressing technique will be designed to increase the residual compressive stresses in Silicon and achieve the crack closure state for any crack and therefore avoid electrical power-losses. An exploitation strategy based on patenting of the technical solution, writing of a business plan, and founding a spin-off/start-up company with a team with interdisciplinary skills will be implemented. This will allow for fund raising and exploitation of the idea also based on the already established industrial contacts.;149500;149500;ERC-2016-PoC;/ERC-POC;SCUOLA IMT (ISTITUZIONI, MERCATI, TECNOLOGIE) ALTI STUDI DI LUCCA;IT;;;;1;0;0;1;0;0 201442;706564;NGUEC;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Nanostructuring graphene under electrochemical control;2016-03-01;2018-02-28;;Graphene, a single atom thick sheet of sp2-hybridized carbon, has recently attracted tremendous interest in both fundamental studies and potential applications due to its unique electronic, optical, mechanical and thermal properties. Despite these exceptional qualities however, some inherent characteristics of graphene itself preclude its widespread usage in technological applications. A prerequisite for the use of graphene in several low- as well as high-end applications is its controlled and reproducible functionalization in a nanostructured fashion, towards doping and band gap opening. Therefore, NGUEC aims to develop experimental protocols for controlled and reproducible functionalization and characterization of graphene in a nanostructured fashion by using chemisorption (covalent) strategies in combination with physisorption (non-covalent) approaches, relying on the power of electrochemical control. The efficiency of these approaches will be followed by combined cyclic voltammetry (CV), electrochemical scanning tunnelling microscopy (EC-STM) and electrochemical Raman (EC-Raman). This is an interdisciplinary project centered at the interface between Supramolecular Chemistry, Electrochemistry, Materials Science and Nanoscience. The ultimate goal of the project is to allow the fellow to attain a position of professional independence at the forefront of future academic or industrial research efforts through a combination of hands-on experience in diverse research disciplines and training in complementary skills.;172800;172800;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;KATHOLIEKE UNIVERSITEIT LEUVEN;BE;;;;1;0;0;1;0;0 194590;649496;EXCEPT;SIGNED;H2020-EU.3.6.;YOUNG-1-2014;H2020;Social Exclusion of Youth in Europe: Cumulative Disadvantage, Coping Strategies, Effective Policies and Transfer;2015-05-01;2018-04-30;;Against the background of increasing labour market insecurities among youth during the recent crisis, the aim of this interdisciplinary and internationally comparative project is to provide a comprehensive understanding of the consequences of youth labour market vulnerability for risks of social exclusion in Europe. A multidimensional dynamic perspective on both objective and subjective dimensions of the social exclusion of young people is adopted in order to identify the complex interrelationships and potential risks of cumulative disadvantages and possible compensatory mechanisms. Specifically, implications of labour market insecurities for youth’s risks of poverty and material deprivation, their subjective well-being and health status as well as their ability to reach independence from parental home are investigated in a mixed-method approach. First, qualitative interviews are conducted with youths from nine selected European countries including Ukraine in order to reach an in-depth understanding of how disadvantaged youths perceive their social situation and try to cope with it in different economic, institutional and cultural environments. Second, quantitative methods are applied using EU-28 and national micro-data in order to identify the causal interrelationships and dynamic processes of youth’s social exclusion in different national contexts. Third, the diffusion and effectiveness of EU and national policies that address various issues of youth social exclusion are assessed in EU-28 based on expert interviews and policy evaluation analyses. A central objective of this comparative project is to learn about examples of best practises and provide suggestions for reforms and policies that help improving the social situation of young people who face labour market insecurities and also involve youth own voice in this process. By involving and addressing different stakeholder groups at all stages of the project the dissemination of results will be ensured.;2497416,25;2497414,75;H2020-YOUNG-SOCIETY-2014;/RIA;TALLINN UNIVERSITY;EE;"ARISTOTELIO PANEPISTIMIO THESSALONIKIS - EIDIKOS LOGARIASMOS KONDILION EREVNAS;Institute for the Study of Societies and Knowledge;UNIVERSITA DEGLI STUDI DI TORINO;UNIVERSITAET DUISBURG-ESSEN;UMEA UNIVERSITET;INSTYTUT BADAN EDUKACYJNYCH;UNIVERSITY OF KENT;INTERNATIONAL CIVIC ORGANISATION KYIV ECONOMICS INSTITUTE;OTTO-FRIEDRICH-UNIVERSITAET BAMBERG";"EL;BG;IT;DE;SE;PL;UK;UA";;1;0;0;1;0;0 218669;812969;FunHoMic;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2018;H2020;Deciphering the fungus-host-microbiota interplay to improve the management of fungal infections;2019-01-01;2022-12-31;;Fungal infections have a major impact on human health, infecting about 2 billion people and killing more people each year than malaria or breast cancer. In particular, Candida species impose a high clinical and economic burden upon the European population. They frequently cause fatal hospital-acquired bloodstream infections. They also cause oral thrush and vaginitis. Most women have suffered an episode of vulvovaginal candidiasis, with ~8% enduring recurrent infections. The initiation and severity of a Candida infection depends on an intricate interplay between the infecting fungal strain and the individual’s immune status and microbiota, all of which can display significant variability. Therefore, for the first time, FunHoMic integrates experts in fungal pathogenesis, immunology, microbial ecology and ‘omics technologies to train 13 Early Stage Researchers (ESRs) who will define and exploit this Fungal-Host-Microbiota interplay to identify novel biomarkers (fungal or host genetic polymorphisms, microbiota profiles, metabolites or immune markers) for the stratification of a patient’s risk of serious fungal infection. This will pave the way for precision medicine in patient management through preventive or therapeutic interventions using antifungals, immune modulators or Live Biotherapeutic Products (LBPs). FunHoMic ESRs will gain broad interdisciplinary skills plus a translational mindset through our integrated, inter-sectoral training program. This will allow Europe to remain at the forefront of translational research in the field of medical mycology. To achieve this vision FunHoMic unites academic partners from France, Germany, The Netherlands, Switzerland, Spain and UK, a French Technology Research Institute with cutting-edge ‘omics technology platforms and three SMEs from The Netherlands, Belgium and France that bring unrivalled organ-on-chip and gastro-intestinal tract simulation technologies and expertise in the development and exploitation of innovative LBPs.;3530871,36;3530871,36;H2020-MSCA-ITN-2018;/MSCA-ITN-ETN;INSTITUT PASTEUR;FR;"PRODIGEST;THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN;MIMETAS BV;STICHTING KATHOLIEKE UNIVERSITEIT;BIOASTER FONDATION DE COOPERATION SCIENTIFIQUE;BIOSE;LEIBNIZ-INSTITUT FUR NATURSTOFF-FORSCHUNG UND INFEKTIONSBIOLOGIE EV HANS-KNOLL-ISTITUT;UNIVERSITAT ZURICH;FUNDACIO HOSPITAL UNIVERSITARI VALL D'HEBRON - INSTITUT DE RECERCA";"BE;UK;NL;FR;DE;CH;ES";;1;0;0;1;0;0 218693;824140;TOCHA;SIGNED;H2020-EU.1.2.2.;FETPROACT-01-2018;H2020;Dissipationless topological channels for information transfer and quantum metrology;2019-01-01;2023-12-31;;The goal of TOCHA is to develop the next generation of topological devices and architectures across which information can flow without losses. This conceptually simple yet technologically and fundamentally challenging requirement is crucial for the development of technologies in fields ranging from information processing to quantum communication and metrology. In each of these areas, the dissipation of information is a key hurdle that leads, for example, to unacceptable thermal loads or error rates. TOCHA will harness topological protection in novel materials and nanoscopic structures to empower electrons, phonons and photons to flow with little or no dissipation and, ultimately, crosslink them within a hybrid platform. This will entail the design of novel topological photonic/phononic waveguides and the engineering of disruptive heterostructures elaborated from the combination of topological insulators and ferromagnetic materials. In the optical domain, this will enable the creation of reflection and scattering free waveguides and, in thermal management, efficient transport and localized dissipation of heat. In electronics, TOCHA will develop ballistic transistors that could operate at THz cut-off frequencies and, for metrology, it will establish a new paradigm for electrical resistance quantization standardization. The hybridization of three distinct quantum particles is expected to lead to novel functionalities, such as the shielding of quantum emitters from phonon-based decoherence processes, or the conversion of information from electronic to optical form and vice versa. TOCHA will gather a young consortium and foster the creation of a new community in Europe on the use of topology for Information and Communication Technologies. Thanks to its high interdisciplinary embodiment involving electronic materials, optics, thermal management and metrology, TOCHA will help advance all levels of the value chain, from fundamental science to engineering and technology.;4997803,75;4997803,75;H2020-FETPROACT-2018-01;/RIA;FUNDACIO INSTITUT CATALA DE NANOCIENCIA I NANOTECNOLOGIA;ES;"PHYSIKALISCH-TECHNISCHE BUNDESANSTALT;Teknologian tutkimuskeskus VTT Oy;COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES;KOBENHAVNS UNIVERSITET;""INSTITUTE OF OPTICAL MATERIALS AND TECHNOLOGIES """"ACADEMICIAN JORDAN MALINOWSKI"""" - BULGARIAN ACADEMY OF SCIENCES"";SIMUNE ATOMISTICS SL;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;JULIUS-MAXIMILIANS-UNIVERSITAT WURZBURG";"DE;FI;FR;DK;BG;ES";;1;0;0;1;0;0 218691;802210;PASSIM;SIGNED;H2020-EU.1.1.;ERC-2018-STG;H2020;Patristic sermons in the Middle Ages. The dissemination, manipulation and interpretation of late-antique sermons in the medieval Latin West;2019-01-01;2023-12-31;;"PASSIM will study the medieval reception of the Latin sermons preached by the Early Church Fathers, using a digital network of manuscripts. The sermons of Augustine, Gregory the Great and other patristic preachers were transmitted throughout medieval Europe in the form of sermon collections, preserved in thousands of manuscripts. Nearly every manuscript contains a new combination of sermons, attesting to a continuous, widespread engagement with the authorities of the Early Church. The dynamic tradition of reorganising and rewriting the patristic heritage is largely overlooked by scholars of medieval religious practices, who concentrate on medieval preachers, and by scholars of Early Christianity, whose focus is the patristic context. Medieval collections of patristic sermons were part of the liturgical life of the monastery, but also of an intellectual tradition. They offer unique insights into medieval attitudes toward authority, techniques of appropriation, church organisation, monastic networks and knowledge exchange. PASSIM will execute the first large-scale analysis of the formation and spread of patristic sermon collections in medieval Europe. The project will develop a digital network of manuscripts, using well-tried principles from the field of textual criticism. Building on this network, PASSIM will pursue three lines of inquiry: the customizing of standard liturgical collections as indicative of individual purposes and contexts, the impact of transmission on the popularity of patristic sermons, and pseudo-epigraphic sermons as revelatory of medieval perceptions of the Church Fathers. PASSIM will bridge two disciplinary divides, between patristic and medieval sermon studies and between textual criticism and reception studies. Developing an interdisciplinary methodology with a wide applicability in the study of intellectual history, this project will introduce patristic preaching as a vibrant strand in the tapestry of the medieval religious tradition.";1474000;1474000;ERC-2018-STG;/ERC-STG;STICHTING KATHOLIEKE UNIVERSITEIT;NL;;;;1;0;0;1;0;0 218716;824103;NEUROTECH;SIGNED;H2020-EU.1.2.2.;FETPROACT-02-2018;H2020;Neuromorphic Technology;2018-11-01;2021-10-31;;"Neuromorphic engineering is a ground-breaking approach to design of computing technology that draws inspiration from the powerful and efficient biological neural processing systems. Neuromorphic devices are able to carry out sensing, processing, and motor control strategies with ultra-low power performance. Today's neuromorphic community in Europe is leading the state of the art in this domain. The community counts an increasing number of labs that work on theory, modelling, and implementation of neuromorphic computing systems using both conventional VLSI technologies, emerging memristive devices, photonics, spin-based, and other nano-technological solutions. To enable the uptake of this technology and to match the needs of real-world applications in future products that solve real-world tasks in industry, health-care, assistive systems, and consumer devices, a strong and sustainable communication channel between research labs and different stakeholders is needed. To achieve this goal, the NEUROTECH project aims to (1) create a comprehensive online platform that will integrate information about all involved parties, the state of the art, and showcase latest technology advancement strengthening the NCT community and increasing its impact and visibility; (2) actively reach out to industry stakeholders to get them involved in shaping future research directions and to facilitate uptake of existing technology; (3) promote public interest in NCT by show-casting key technologies; and (4) shape educational resources in this interdisciplinary field targeting students with different backgrounds. The CSA will be the connecting element that will allow us to consolidate and disseminate the state of the art of neuromorphic technology and to create a transforming roadmap for future progress, unleashing the power of NCT in smart technologies of the future.";512393,75;512393,75;H2020-FETPROACT-2018-01;/CSA;UNIVERSITAT ZURICH;CH;"THE UNIVERSITY OF HERTFORDSHIRE HIGHER EDUCATION CORPORATION;THE UNIVERSITY OF MANCHESTER;COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES;INTERUNIVERSITAIR MICRO-ELECTRONICA CENTRUM;IBM RESEARCH GMBH;RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG;FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA;CONSIGLIO NAZIONALE DELLE RICERCHE;UNIVERSITE DE BORDEAUX;THALES SA;UNIVERSITAET BIELEFELD";"UK;FR;BE;CH;DE;IT";;1;0;0;1;0;0 218701;802918;DUNES;SIGNED;H2020-EU.1.1.;ERC-2018-STG;H2020;Sea, Sand and People. An Environmental History of Coastal Dunes;2018-11-01;2023-10-31;;"Dunes are now protected environments, being top priority for coastal managers, because of their important role as coastal defences. But, it was not like that in the past. For centuries dunes were considered unproductive and dangerous. The sand blown by the wind was taken inland, invading fields, silting rivers and destroying villages. In the eighteenth century, a strategy was developed to fight against the dunes: trapping them with trees, with the double purpose of preventing the destruction of arable land and increasing their economic value converting them into forest areas. Different governments, in different countries supported the immobilization of the shifting sands. The strategy, developed in Europe, was taken to other places in the world. These works caused profound changes in vast coastal areas transforming arid landscapes of sandy dunes into green tree forests. This project aims to explore human-environment relations in coastal areas worldwide, since the eighteenth century until today, through the study of dunes as hybrid landscapes. Based on selected case-studies and comparative approaches, the project will focus on the origins, reasons and means of dunes afforestation; the impacts of the creation of new landscapes to local communities and ecosystems; and the present situation of dunes as coastal defences and rehabilitated environments. The final purpose is to produce an innovative global history of coastal dunes, combining knowledges from both Humanities and Social Sciences and Physical and Life Sciences, which has never been done. Supported by an interdisciplinary team, this research will result in new developments in the field of the Environmental History studies; provide relevant knowledge considering the need of efficient management solutions to adapt to the expected mean sea level rise; and stimulate environmental citizenship by disseminating the idea that the future of the world coasts depends on today’s actions.";1062330;1062330;ERC-2018-STG;/ERC-STG;Faculdade de letras da Universidade de Lisboa;PT;;;;1;0;0;1;0;0 218672;813547;MIDA;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2018;H2020;Mediating Islam in the Digital Age. Present issues and past experiences of technological revolutions;2019-03-01;2023-02-28;;"We are witnessing the emergence of what is in very important ways essentially a new religion. Digitisation and globalisation have influenced not only social and political practices and organisation, but also religious beliefs and practices. Islam, the Islamic commonwealth and the Muslims, are at the forefront of the most recent developments. Hitherto relatively marginal theological and ideological trends have acquired new prominence within Islam and this new Islam is being disseminated as a brand in an ever-expanding corpus of public images and imaginaries. This newly acquired hyper-visibility is reminiscent of the impact of the printing press on the Catholic church in the 16th century, and its role in the Reform movement. The impact today of technological innovations on the development of Islam requires urgent assessment. The MIDA proposal aims to understand how digitisation is shaping Islam (i.e. beliefs, practices, political and social institutions, and outlooks). How is this technological revolution modifying the relation Muslims have with the past? Why is it reshaping Islam in more profound ways than other monotheisms? We need to understand the developments that are transforming religious belief in our time and to do so scholarship itself needs to seize the resources of the technological revolution that is spurring change. The MIDA project will make possible the necessary training of a group of young researchers, able to answer collectively to the challenge, providing them inter-sectoral, interdisciplinary, international skills. To tackle the complexity of the issue, five interlocking work packages have been designed, each including comparative work on historical case-studies: ‘Narratives of the Self’; ‘Languages and Translation’; ‘Images and Materiality in Islam’; ‘Contested Authority and Knowledge Production’ and ‘Mobility and Mobilisation beyond Borders’.";3874112,28;3874112,28;H2020-MSCA-ITN-2018;/MSCA-ITN-ETN;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FR;"PHILIPPS UNIVERSITAET MARBURG;UNIVERSITEIT LEIDEN;STICHTING VU;STICHTING KATHOLIEKE UNIVERSITEIT;AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS;GIGA GERMAN INSTITUTE OF GLOBAL ANDAREA STUDIES STIFTUNG;FONDACIJA KULTURNO NASLIJEDE BEZ GRANICA;INSTITUT DE RECHERCHE POUR LE DEVELOPPEMENT;KATHOLIEKE UNIVERSITEIT LEUVEN;FREIE UNIVERSITAET BERLIN;UNIVERSITEIT VAN AMSTERDAM";"DE;NL;ES;BA;FR;BE";;1;0;0;1;0;0 218680;824060;ACDC;SIGNED;H2020-EU.1.2.2.;FETPROACT-01-2018;H2020;Artificial Cells with Distributed Cores to Decipher Protein Function;2019-01-01;2023-01-31;;"We envision a future where ‘chemical apps’ on mobile devices produce on demand valuable compounds for health and performance as well as apps for bioagent threat detection and disease. To take concrete and defined steps toward this future vision, we will exploit the miniaturization provided by lab on a chip technology and construct responsive architectures and metabolism based on living cells and tissues. We will build programmable and re-configurable, (bio)chemical processes, with precision, order, and as hierarchical cellular constructs, in the same way as living systems. We will enable microscale, liquid-based, chemical compartmentalisation (cores), and inter-compartmental (core-core) communication, just as one finds in organelles, cells and tissues. ACDC will focus on developing this next generation technology through a detailed workplan that heavily involves the nontrivial tasks of integrating diverse state of the art technologies including microfluidics, microwave resonators, DNA-based supramolecular assembly, in vitro gene expression and the integration of membrane channels into a functional platform. In a future embodiment of this project, artificial cell technology will be used as programmable and reconfigurable matter for specific applications, including theranostics and personalized medicine as well as sensing and actuation in the environments for bioremediation. As the first steps towards that future vision, we aim to produce an artificial technological construct and process that recapitulates some aspects of living systems on the microscale, and therefore this project will produce exemplars of secondary living technologies concentrating on the wetware class [1] but also a multi-level mathematical framework. We have assembled an international, interdisciplinary team from academia, industry and public engagement. Our outreach and engagement programme will define the impact in both the public and economic sectors with ethical dimensions considered. Further, building upon 55 years of collective start-up enterprise experience, we will explore the translation of new intellectual property generated into commercial advantage and job creation for the European Union.";4376295;4376295;H2020-FETPROACT-2018-01;/RIA;UNIVERSITA DEGLI STUDI DI TRENTO;IT;"ELVESYS SAS;EXPLORA SRL;MUSEO DELLE SCIENZE;ZURCHER HOCHSCHULE FUR ANGEWANDTE WISSENSCHAFTEN;CARDIFF UNIVERSITY";"FR;IT;CH;UK";;1;0;0;1;0;0 218622;802830;LIGHTPORT;SIGNED;H2020-EU.1.1.;ERC-2018-STG;H2020;From light-stimulated anion receptors to transmembrane carriers and pumps;2019-03-01;2024-02-29;;"The transport of anions across the cell membrane, which is mediated by transport proteins, is essential to many important biological processes. Dysregulation of this transport has been associated to various diseases and therefore, chemists endeavour to develop artificial receptors that mimic the function of natural transporters. Despite much progress over the last decade, the current artificial systems are mostly static, while proteins are able to change their activity dynamically in response to stimuli in the environment. To integrate such stimuli-controlled behavior in synthetic systems is a key contemporary challenge. In view of this, the goal of the proposed research program is to develop anion receptors in which the binding properties can be effectively modulated by light and to apply these receptors as transmembrane carriers and pumps, in order to regulate passive transport (i.e. down a concentration gradient) and to induce active transport (i.e. against a concentration gradient). This interdisciplinary program is divided into three work packages: WP1 aims at the development of structurally rigid and visible-light-actuated photoswitches and their use as platforms for constructing anion receptors; WP2 deals with the development of mechanically interlocked structures as photoswitchable anionic hosts; WP3 is directed at utilizing these receptors for light-gated transport and light-driven pumping of anions across phospholipid bilayers, whereas also an alternative dual-responsive anion channel will be prepared. Eventually, it is expected that this work will open a new route toward light-based localized pharmacological treatment, e.g. via light-triggered cancer or bacterial cell death. Furthermore, active transport systems, that are able to build up and maintain concentration gradients across membranes, could provide a completely new view on how to convert and store light (solar) energy.";1499461;1499461;ERC-2018-STG;/ERC-STG;RIJKSUNIVERSITEIT GRONINGEN;NL;;;;1;0;0;1;0;0 218610;822214;NeEDS;SIGNED;H2020-EU.1.3.3.;MSCA-RISE-2018;H2020;Research and Innovation Staff Exchange Network of European Data Scientists;2019-01-01;2022-12-31;;"NeEDS responds to the massive scientific and technological challenges that the very rapidly growing field of Data Science has created for users and producers of data in Europe and world-wide. The challenges stem from the complexity of the data, the completely novel questions posed to data scientists, as well as the need of non-experts to visualize and interact with the knowledge extracted from data in order to aid data-driven decision-making. Companies and public sector bodies around Europe find they cannot build up the required capabilities quickly enough, and Europe is remarkably behind US academia in increasing Data Science capacity. NeEDS provides an integrated modelling and computing environment that facilitates data analysis and data visualization to enhance interaction. NeEDS brings together an excellent interdisciplinary research team that integrates expertise from three relevant academic disciplines, Mathematical Optimization, Visualization and Network Science, and is excellently placed to tackle the challenges. NeEDS develops mathematical models, yielding results which are interpretable, easy-to-visualize, and flexible enough to incorporate user knowledge from complex data. These models require the numerical resolution of computationally demanding Mixed Integer Nonlinear Programming formulations, and for this purpose NeEDS develops innovative mathematical optimization based heuristics. NeEDS consists of four academic beneficiaries, eight industrial beneficiaries (from industry sectors ranging from energy, retailing, insurance to banking, as well as national statistical offices), two academic partners and one industrial partner from five EU countries, USA and Latin America with strong and complementary expertise. With this composition, NeEDS is in a unique position to deliver cutting-edge multidisciplinary research to advance academic thinking on Data Science in Europe, and to improve the Data Science capabilities of industry and the public sector.";1168400;1168400;H2020-MSCA-RISE-2018;/MSCA-RISE;COPENHAGEN BUSINESS SCHOOL;DK;"GEOGRAFIA APLICADA SL;REPSOL SA;DANMARKS STATISTIK;AGEAS SA;TESCO STORES LIMITED;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;CENTRAAL BUREAU VOOR DE STATISTIEK;INFORMATICA EL CORTE INGLES SA;KATHOLIEKE UNIVERSITEIT LEUVEN;UNIVERSIDAD DE SEVILLA";"ES;DK;BE;UK;NL";;1;0;0;1;0;0 218600;804920;CAFYR;SIGNED;H2020-EU.1.1.;ERC-2018-STG;H2020;Constructing Age for Young Readers;2019-02-01;2024-01-31;;"Constructing Age for Young Readers (CAFYR) CAFYR starts from the observations that Europe has recently witnessed a few pertinent crises in intergenerational tension, that age norms and ageism frequently go unchecked and that they are part of children’s socialization. It aims at developing pioneering research for understanding how age is constructed in cultural products. CAFYR focuses on fiction for young readers as a discourse that often naturalizes age norms as part of an engaging story and that is endorsed in educational contexts for contributing to children’s literacy, social and cultural development. The effect of three factors on the construction of age in children’s books is studied: the age of the author, the age of the intended reader, and the age of the real reader. CAFYR aims to lay bare whether and how the age and aging process of children’s authors affect their construction of the life stages in their works. It will show how various crosswriters shape the stages in life differently for young and adult readers. It considers the age of young readers as varied in its own right, and investigates how age is constructed differently for children of different ages, from preschoolers to adolescents. Finally, it brings together readers of various stages in the life course in a reception study that will help understand how real readers construct age, during the reading process and in dialogue with each other. CAFYR also aims to break new theoretical and methodological ground. It offers an interdisciplinary approach that enriches children’s literature research with concepts and theories from age studies. It combines close reading strategies with distant reading and tools developed for digital text analysis. It provides a platform to people of different stages in life, contributing to their awareness about age, and facilitating and investigating dialogues about age, with the aim of ultimately fostering them more.";1400885;1400885;ERC-2018-STG;/ERC-STG;UNIVERSITEIT ANTWERPEN;BE;;;;1;0;0;1;0;0 218586;812716;CHARMING;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2018;H2020;Chemical Engineering Immersive Learning;2018-11-01;2022-10-31;;"The chemical industry in Europe faces stiff competition as it fights to strengthen its position in the global market place. Europe’s greatest asset is its human capital, but the people working in such a technology-based environment, with the rise of the “smart factories” of Industry 4.0, need to be very well qualified. The situation of yesteryear, where a person could be trained to carry out a job for the whole of his/her career has long since gone; now the situation is one of developing skills and competencies, but then being able to adapt, re-learn and be able to cross sectors and disciplines in a world of work that is dynamic and subject to constant change. Continuous professional development, the stimulation of creative thinking and the motivation of youngsters for science & technology are high on the EU’s agenda. Recent developments in immersive learning technologies are providing exciting new tools for teaching and training programmes, yet they remain underutilised in science & technology education, and nowhere is this more true than in the field of chemistry and chemical engineering. CHARMING, the European Training Network for Chemical Engineering Immersive Learning, takes on this challenge by developing learning strategies, content and prototypes for the application of games and virtual/augmented reality for motivating, teaching and training children, students and employees in chemistry, chemical engineering and chemical operations. The inter-sectorial and interdisciplinary CHARMING ETN consists of leading universities and industry participants and trains 15 ESRs in the areas of innovative chemical engineering, instructional psychology & pedagogy and immersive technology. CHARMING’s success is based on integrating these three areas, in order to provide Europe with its highly trained young experts who are ready to help motivating, training and integrating the next-generation human capital of the European chemical industry and beyond.";4060227,6;4060227,6;H2020-MSCA-ITN-2018;/MSCA-ITN-ETN;KATHOLIEKE UNIVERSITEIT LEUVEN;BE;"IT-UNIVERSITETET I KOBENHAVN;LUGUS STUDIOS;UNIVERSITY OF NEWCASTLE UPON TYNE;MERCK KOMMANDITGESELLSCHAFT AUF AKTIEN;ARKEMA FRANCE SA;UNIVERSITEIT UTRECHT;UNIVERSITAET BIELEFELD";"DK;BE;UK;DE;FR;NL";;1;0;0;1;0;0 218582;812616;PoLiMeR;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2018;H2020;Polymers in the Liver: Metabolism and Regulation;2018-10-01;2022-09-30;;"Metabolic diseases are a burden on the European population and health care system. It is increasingly recognised that individual differences with respect to history, lifestyle, and genetic make-up affect disease progression and treatment response. A Systems Medicine approach, based on computational models fed with individual patient data, has the potential to provide the basis for a personalised diagnosis and treatment strategy. The PoLiMeR consortium (Polymers in the Liver: Metabolism and Regulation) has identified the inherited, liver-related diseases of glycogen and lipid metabolism as the ideal starting point for innovative research training in personalised ‘Systems Medicine’. Our perspective opens possibilities for the application of novel drugs and diagnostic tools to a range of both rare and frequent diseases. To advance diagnostics and treatment of metabolic diseases beyond the state-of-the art, a new generation of scientists is needed. The complexity of the metabolic network and its aberrant behaviour in disease require experts with a deep knowledge and understanding of Systems Medicine approaches. The lack of truly interdisciplinary researchers, trained in the three ‘pillars of Systems Medicine’ - experimental, computational and clinical research - severely hampers progress in this field. PoLiMeR aims to fill this gap and brings together clinical, academic, and industrial experts on inherited metabolic diseases, computational modelling of the entire human metabolism, organ-on-chip technology, and detailed metabolic profiling. Our mission is to train our Early Stage Researchers (ESRs) to become dedicated Systems-Medicine experts, who can seamlessly collaborate between computational and wet-lab environments, and between clinical, academic, and industrial environments. This training will enable them to become the future leaders in the field and eventually make the difference for the patients.";4035447,54;4035447,54;H2020-MSCA-ITN-2018;/MSCA-ITN-ETN;ACADEMISCH ZIEKENHUIS GRONINGEN;NL;"HEINRICH-HEINE-UNIVERSITAET DUESSELDORF;MIMETAS BV;UNIVERSITEIT LEIDEN;KUNGLIGA TEKNISKA HOEGSKOLAN;HITS GGMBH;JOHN INNES CENTRE;UNIVERSITE DU LUXEMBOURG;CARL VON OSSIETZKY UNIVERSITAET OLDENBURG;UNIVERSITAETSKLINIKUM FREIBURG;ICENI DIAGNOSTICS LIMITED;UNIVERSITETET I BERGEN";"DE;NL;SE;UK;LU;NO";;1;0;0;1;0;0 218578;804599;MARIPOLDATA;SIGNED;H2020-EU.1.1.;ERC-2018-STG;H2020;The Politics of Marine Biodiversity Data: Global and National Policies and Practices of Monitoring the Oceans;2018-11-01;2023-10-31;;In order to protect marine biodiversity and ensure that benefits are equally shared, the UN General Assembly has decided to develop a new legally binding treaty under the United Nations Convention on the Law of the Sea. Marine biodiversity data will play a central role: Firstly, in supporting intergovernmental efforts to identify, protect and monitor marine biodiversity. Secondly, in informing governments interested in particular aspects of marine biodiversity, including its economic use and its contribution to biosecurity. In examining how this data are represented and used, this project will create a novel understanding of the materiality of science-policy interrelations and identify new forms of power in global environmental politics as well as develop the methodologies to do so. This is crucial, because the capacities to develop and use data infrastructures are unequally distributed among countries and global initiatives for data sharing are significantly challenged by conflicting perceptions of who benefits from marine biodiversity research. Despite broad recognition of these challenges within natural science communities the political aspects of marine biodiversity data remain understudied. Academic debates tend to neglect the role of international politics in legitimising and authorising scientific concepts, data sources and criteria and how this influences national monitoring priorities. The central objective of MARIPOLDATA is to overcome these shortcomings by developing and applying a new multiscale methodology for grounding the analysis of science-policy interrelations in empirical research. An interdisciplinary team, led by the PI, will collect and analyse data across different policy-levels and spatial scales by combining 1) ethnographic studies at intergovernmental negotiation sites with 2) a comparative analysis of national biodiversity monitoring policies and practices and 3) bibliometric and social network analyses and oral history interviews for mapping marine biodiversity science.;1391932;1391932;ERC-2018-STG;/ERC-STG;UNIVERSITAT WIEN;AT;;;;1;0;0;1;0;0 218557;789119;DYNACEUTICS;SIGNED;H2020-EU.1.1.;ERC-2017-ADG;H2020;Remote control healing: Next generation mechano-nano-therapeutics;2019-01-01;2023-12-31;;"Imagine if doctors could heal patients via remote control. Following simple injections into regions of the body, they could activate internal cells by an external bandage. In this way, they could remotely control the ways tissue heal. This Advanced grant sets out to understand, design and develop the mechano-nano-magnetic platform that will underpin this therapeutic strategy for the future – DYNACEUTICS. Key receptors have been identified such as ion channels, integrins and growth factors which respond to mechanical cues on the membrane and activate downstream pathways. How do we ‘bottle’ an agonist like a drug which can influence or regulate mechano-sensors on the membrane and can be controlled remotely? This project tackles this complex interdisciplinary question through breakthrough nanotechnologies. We aim to expand and develop a platform technology using magnetic particle tagging which will allow us to direct cells for therapeutic purposes. Specifically, we aim • to identify mechano-receptor binding sites on stem and mature cells which will enable remote activation of signalling pathways via magnetic fields, • to design and test magnetic particles with tailored tagging strategies using single cell through 3D human organoid models to in vivo disease models, • to tailor and design external remote control devices • to create clinically relevant treatment modalities for remote control healing. This proposal presents a unique opportunity to launch a new dynamic treatment platform, DYNACEUTICS, which we propose will extend the therapeutic horizon and provide a new form of remote controlled healing.";2499068;2499068;ERC-2017-ADG;/ERC-ADG;THE UNIVERSITY OF BIRMINGHAM;UK;;;;1;0;0;1;0;0 218500;812818;MICROCOMB;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2018;H2020;Applications and Fundamentals of Microresonator Frequency Combs;2019-01-01;2022-12-31;;The proposed network will establish and support cross-sectorial training and research programme bringing together leading European academic and industrial centers working in the area of optical frequency combs in microresonators (microcombs). The programme will allow to combine and share some of the world leading experience and expertise in the microcombs and train a new generation of scientists in this actively developing area bordering physics and photonic engineering and having pronounced applied and fundamental dimensions. The frequency comb research itself is the Nobel prize winning area (T. Hänsch and J. Hall, 2005), while the microcombs can qualify as an emerging disruptive technology. Europe still lacks a structured and comprehensive training programme in this area, which is proposed by our consortium, while facing a growing competiton with its global rivals. This programme will have a lasting impact increasing European innovation capacity through expanding knowledge base, new IP, trained personnel, better equipped laboratories and future collaborations leading to product development. Our project addresses research and technology problems with interdisciplinary importance from the areas of precision frequency metrology, ultrafast data processing, optical to RF signal conversion, astronomical measurements and soliton physics. Early stage researchers involved into the proposed network will receive broad and well balanced training in device characterisation and fabrication, experimental techniques and theory and modeling in best academic, research center and industrial environments. A programme of secondments and network wide events will ensure highest levels of cross-country and academia-industry mobility for our researchers. Soft-skills training events organised by such industrial consortium members as IBM, Menlo and AIRBUS will provide our researchers with career perspectives beyond their immediate research focus.;4088480,4;4088480,4;H2020-MSCA-ITN-2018;/MSCA-ITN-ETN;UNIVERSITY OF BATH;UK;"NPL MANAGEMENT LIMITED;KUNGLIGA TEKNISKA HOEGSKOLAN;UNIVERSITEIT GENT;ALBERT-LUDWIGS-UNIVERSITAET FREIBURG;IBM RESEARCH GMBH;ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE;Menlo Systems GmbH;KARLSRUHER INSTITUT FUER TECHNOLOGIE;UNIVERSITAT POLITECNICA DE VALENCIA;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;CHALMERS TEKNISKA HOEGSKOLA AB";"UK;SE;BE;DE;CH;ES";;1;0;0;1;0;0 218293;823942;FUNCOAT;SIGNED;H2020-EU.1.3.3.;MSCA-RISE-2018;H2020;Development and design of novel multiFUNctional PEO COATings;2019-01-01;2022-12-31;;"The main objective of the proposal is the development of multi-purpose, multi-functional surfaces via environmentally friendly plasma electrolytic oxidation (PEO) treatments. In an intelligent way the weakness of the PEO process (the inherent porosity due to the discharges forming the coating is often responsible for poor properties) is used to functionalize the coating using the open pore structure as a reservoir for nanocontainer or to bring particles with certain functionalities deep into the coatings (fast pathways). The main targeted functionalities, are enhanced fault tolerance and active protection against corrosive damage as well as improved tribological behavior. Moreover, to extend this typical field of applications of PEO treatments and address additional industries and aspects (e.g. 3C, ecological), a set of less common functionalities, such as photocatalytic, magnetic, thermo- and electroconductivity will be added. This is challenging and goes far beyond the state-of-the-art introduction via post-treatments. To deal with such sensitive materials, changes in the power supply are required and this is addressed as one of the key points in frame of the project as well. The essential key of the project is the formation and development of an interdisciplinary R&D partnership, where participants from both academia (5) and private sector (4 SME) participate, promoting and sharing their ideas, expertise, techniques and methods to solve this demanding challenge. This partnership will be beneficial for all participants, since new PEO hardware, environmentally friendly processes and applications important for industry are developed, evaluated and promoted by the research institutions via presentations and publications of the obtained results. Laboratory based training and intersectional transfer of knowledge are the key aspects of the FUNCOAT project, so the partnership gathers the topmost competences to carry out the suggested research program.";1301800;1301800;H2020-MSCA-RISE-2018;/MSCA-RISE;HELMHOLTZ-ZENTRUM GEESTHACHT ZENTRUM FUR MATERIAL- UND KUSTENFORSCHUNG GMBH;DE;"FACULTY OF PHYSICS OF THE UNIVERSITY OF BELGRADE;SMALLMATEK - SMALL MATERIALS AND TECHNOLOGIES LDA;COMPANY FOR TRADE AND SERVICES CHEMICAL AGROSAVA DOO BELGRADE (NOVI BEOGRAD);UNIVERSIDADE DE AVEIRO;TEHNOLABOR OU;MEOTEC GMBH & CO KG";"RS;PT;EE;DE";;1;0;0;1;0;0 218076;824015;INCOGNITO;SIGNED;H2020-EU.1.3.3.;MSCA-RISE-2018;H2020;IdeNtity verifiCatiOn with privacy-preservinG credeNtIals for anonymous access To Online services;2019-01-01;2022-12-31;;"The overarching goal of INCOGNITO is to combine state-of-the-art technologies in a platform that will allow users to easily understand what is needed to access online services with respect to their privacy and be able to prove specific attributes of their identity or their whole identity. We build on top of the framework that is being developed under the ReCRED project where we use advanced mobile software in order to convert online and physical identity proofs into validated and cryptographically strong proofs of identities that can be used for getting access to Online Services. INCOGNITO has the following objectives: 1.Design and implement an infrastructure that supports qualified anonymity (QA) by leveraging state of the art cryptographic credentials schemes as well as Federated Login solutions. 2.Design and implement an Identity Acquisition and Management platform that will allow the user to quickly and securely acquire identity attributes from Physical ID documents and Online Identities. 3.Design and implement an advanced UI/UX AI-based assistant that will guide and inform the user about aspects of his identity management as well as possible actions to take. 4.Evaluate the results of the project through two pilot activities. To achieve these objectives an inter-sectorial and interdisciplinary secondment program for Experienced and Early Stage Researchers that fosters knowledge exchange is proposed. Academic partners will offer their expertise on online identity acquisition and management, machine-learning algorithms and user experience assessment. Industry partners will offer their expertise on state-of-the-art IT security technologies, production-grade development processes, exposure to industrial research environment and relevant business issues and data.";1173000;1173000;H2020-MSCA-RISE-2018;/MSCA-RISE;UNIVERSITY OF PIRAEUS RESEARCH CENTER;EL;"TECHNOLOGIKO PANEPISTIMIO KYPROU;TELEFONICA INVESTIGACION Y DESARROLLO SA;KAIZEN DIGITAL YPIRESIES DIACHIRISIS PROOTHISIS KAI YPOSTIRIXIS LOGISMIKON EFARMOGON ANONYMI ETAIRIA;CERTSIGN SA;LSTECH ESPANA SL";"CY;ES;EL;RO";;1;0;0;1;0;0 218504;813834;pHioniC;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2018;H2020;pH and Ion Transport in Pancreatic Cancer;2018-11-01;2022-10-31;;"pHioniC brings together highly synergistic expertise, research and training facilities to investigate pancreatic ductal adenocarcinoma (PDAC), a frequent and aggressive cancer that is still incurable. The programme’s central hypothesis has a strong grounding in the physiology of the exocrine pancreas. Secretion of the alkaline pancreatic juice, normally associated with digestion, leads to acidifications of the pancreas stroma resulting in an acid adaptation of pancreatic cells. We are first to propose that this adaptation facilitates PDAC initiation and progression by selecting for more aggressive phenotypes in interplay with PDAC driver mutations. pHioniC will: (i) develop models (e.g. pancreas-/PDAC-specific pH-indicator mouse) to map the pH landscape in the normal and diseased pancreas, (ii) characterize the impact of the acidic microenvironment in PDAC development and (iii) design bespoke approaches to the treatment of PDAC that exploit the unique physiology of the pancreas and utilize a combination of nanocarrier and antibody technology for targeting. Thereby, pHioniC provides an innovative interdisciplinary and intersectoral training for ESRs at the forefront of oncological research. pHioniC comprises excellent complementary basic-research, clinical, and in silico laboratories that provided the seed discoveries for this novel concept, and industrial partners with a track record in therapeutic and diagnostic development in oncology. This highly synergistic team combines the state-of-the-art research tools and translational opportunities needed to meet the most ambitious doctoral programmes. pHioniC training for ESRs covers the fields of ion transport, oncology, imaging, bioinformatics and antibody technology, and is complemented by extensive transferable skills and personalised training elements. pHioniC will establish a lasting contribution towards European doctoral training beyond the lifetime of the project.";4027619,16;4027619,16;H2020-MSCA-ITN-2018;/MSCA-ITN-ETN;WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER;DE;"UNIVERSITE DE PICARDIE JULES VERNE;HEIDELBERG PHARMA RESEARCH GMBH;PERCUROS BV;DEBRECENI EGYETEM;UNIVERSITA DEGLI STUDI DI FIRENZE;KOBENHAVNS UNIVERSITET;CHRISTIAN-ALBRECHTS-UNIVERSITAET ZU KIEL;UNIVERSITE DE LILLE;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;UNIVERSITA DEGLI STUDI DI BARI ALDO MORO";"FR;DE;NL;HU;IT;DK;UK";;1;0;0;1;0;0 217935;802349;SILVER;SIGNED;H2020-EU.1.1.;ERC-2018-STG;H2020;Silver and the Origins of the Viking Age;2019-03-01;2024-02-29;;"This project will address one of the enduring questions of medieval studies - the origins of the Viking Age (c. 750-1050 AD) - through an interdisciplinary (archaeological, archaeometric and numismatic) study of silver from early Viking-Age Scandinavia.  In doing so, it will provide the first large-scale, systematic and empirically-based answers to the outstanding questions of where, when and why the Viking Age began, casting vital new light on what is widely recognised to be a pivotal episode of cultural expansion in Eurasia. As the only surviving physical evidence from the spoils of Viking expansion, silver has unique potential to elucidate the early development of the Viking Age. Its geographic origins can reveal where Viking activity was concentrated (Western Europe vs. Baltic/ Russia); its uses can indicate why the Vikings were prepared to risk their lives acquiring it (social vs. monetary function); and its chronology can unlock the timings of the main periods of expansion (ninth century, as widely believed, vs. a century earlier). Yet, due to its poor characterisation and the lack of scientific approaches to its study, silver has never before been harnessed to address these fundamental topics. This project will build an entirely new dataset of the ninth-century ‘silver record’ from a combination of access to museum collections and fresh artefact and coin identifications made by the project team. We will analyse this material in new ways. First-hand archaeological and numismatic study will be combined with pioneering methods in archaeometric analysis, the enormous potential of which for revealing Viking silver sources has recently been demonstrated by the PI. The PI has negotiated unprecedented permissions from national museums to extend scientific analyses to early Viking silver objects from across Northern Europe. There is now a tremendous opportunity to transform understanding of one of Europe’s most significant cultural movements.";1499830;1499830;ERC-2018-STG;/ERC-STG;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;UK;;;;1;0;0;1;0;0 218499;813284;INTEGRATA;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2018;H2020;Integrating chemical and biological approaches to target NAD production and signaling in cancer;2018-11-01;2022-10-31;;"Deregulated nicotinamide adenine dinucleotide (NAD) biosynthesis and signaling underlies many aspects of carcinogenesis. NAD biosynthetic enzymes, such as nicotinamide phosphoribosyltransferase (NAMPT) and nicotinic acid phosphoribosyltransferase (NAPRT), are commonly upregulated in cancer cells, where they fuel increased metabolic demands and downstream enzymes involved in DNA repair and in the promotion of cell growth, cell motility, de-differentiation and immune escape. In addition, NAD-producing enzymes, such as NAMPT, moonlight in the extracellular space, exerting strongly pro-oncogenic, autocrine and paracrine effects. Many of these roles of NAD-producing and NAD-utilizing enzymes appear to be shared between solid and haematological cancers. Thus, agents targeting NAD production or signaling are expected to have broad applicability. INTEGRATA will: 1. develop new NAD biosynthesis and NAD/nucleotide signaling inhibitors; 2. assess pharmacology and toxicity of the new therapeutics in preclinical models; 3. achieve the proof-of-concept of activity of the newly generated agents in relevant in vivo cancer models. INTEGRATA will train 14 PhD students in an overarching, interdisciplinary training programme that will include training-by-research, joint courses of technical, scientific, and transferrable skills, active participation to public scientific events, and an intense intersectoral networking exchange plan. The INTEGRATA Consortium encompasses academic institutions, research centres, and SMEs/biotech pharma, all with proven experience in higher education and training, and geared with state-of-the-art scientific and technical expertise and infrastructures.";3738573;3738573;H2020-MSCA-ITN-2018;/MSCA-ITN-ETN;UNIVERSITA DEGLI STUDI DI GENOVA;IT;"HEIDELBERG PHARMA RESEARCH GMBH;THE UNIVERSITY OF SHEFFIELD;UNIVERSITE DE GENEVE;UNIVERSITAETSKLINIKUM BONN;UNIVERSITE DE MONTPELLIER;UNIVERSITA DEGLI STUDI DI TORINO;CENTRE HOSPITALIER UNIVERSITAIRE VAUDOIS;INNOVAMOL SRLS;UNIVERSITAETSKLINIKUM HAMBURG-EPPENDORF;UNIVERSITA DEGLI STUDI DI TRENTO;NOVIMMUNE SA;UNIVERSIDAD DE SEVILLA";"DE;UK;CH;FR;IT;ES";;1;0;0;1;0;0 218039;792776;NEVADA;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Novel microengineered environments for mouse embryonic stem cell (mESC) differentiation towards cardiomyocytes;2018-09-01;2020-08-31;;Cardiomyocytes (CMs) are the contractile cells of the heart. Their regenerative capacity is lost after birth. Embryonic stem cells (ESCs) are able to differentiate into functional CMs, however this process is not yet efficient. The elucidation of ESCs’ differentiation into CMs could provide an additional avenue for therapeutic interventions and disease modeling. This interdisciplinary project will result in a unique platform that targets precise quantification of the fundamental molecular mechanisms underlying mouse ESC cardiac differentiation at the single cell level. The platform takes the advantages of 3D tailored conductive microscaffolds (3DTCMSs) to deliver precise mechanical and electrical stimulation patterns to individual cells in vitro. Co-integrated 3DTCMSs have the necessary infrastructure for long-term cell culturing. The platform is accessible for in situ high-resolution, real-time microscopic observation of essential molecular information due to transparent materials. Advanced two-photon polymerization photolithography will be utilized for the exact reconstruction of 3DTCMSs based on a novel optically transparent, conductive ionic liquid-polymer composite. ESC pluripotent factors and CM markers will be monitored comparatively by live microscopy and molecular analysis. This project aims to integrate expertise in materials science, engineering, cellular and molecular biology. As a result, a novel in vitro CM differentiation model will be developed, which has a potential to open a completely new window of research in systems biology.;175419,6;175419,6;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH;CH;;;;1;0;0;1;0;0 218030;792177;LiDeNiAc;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Ligand Design for Nitrogen Activation;2018-06-01;2020-05-31;;"Nitrogen plays a vital role in the production of sufficient crops to feed a growing global population. While atmospheric nitrogen cannot be directly assimilated by plants, bacteria can fix nitrogen under mild conditions to provide bio-available ammonia. In contrast, industrially ammonia is produced under harsh conditions in the Haber Bosch process, which is energy intensive and accompanied by massive emissions of CO2. Therefore, this project seeks to explore more sustainable pathways of dinitrogen activation and its subsequent functionalization. The utilization of renewable N2 is also in line with the “Resource-efficient Europe” flagship initiatives to optimize the use of materials in order to lower the environmental impact. Systems capable of dinitrogen activation in homogenous solution usually build on highly reduced transition metal complexes. In the proposed studies a novel class of polydendate ligands incorporating phosphaalkenes as a design feature will be synthesized to provide a potent platform for further functionalization. The experienced researcher will utilize these ligands as a donor to stabilize low-valent, highly reactive complexes of the bio-relevant metals molybdenum and vanadium. In a last step these systems will be tested in the activation of dinitrogen and their electronic structure will be comprehensively characterized, in a collaborative manner within the host institute, providing the applicant with high-quality technical training. The project links various sub-disciplines of chemistry and is therefore clearly interdisciplinary, combining the applicants experience in inorganic chemistry with the host-institute’s leadership in catalysis. It is therefore expected that the proposed studies represent an opportunity for the experienced researcher to acquire new skills in the design of ligands for novel complexes capable of nitrogen activation, which is expected to further sharpen the researcher's profile and to benefit his future career.";171460,8;171460,8;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;LEIBNIZ - INSTITUT FUR KATALYSE EV AN DER UNIVERSITAT ROSTOCK;DE;;;;1;0;0;1;0;0 218354;803634;ULTRA-FAST;SIGNED;H2020-EU.1.1.;ERC-2018-STG;H2020;VIDEOGRAPHY OF ULTRAFAST PHENOMENA USING THE FRAME CONCEPT;2019-04-01;2024-03-31;;"Scientists have always been particularly intrigued by the extremes in nature and made significant efforts to study these; microscopes allow us to observe the smallest objects, while telescopes permit us to explore the largest objects and also those farthest away. The work proposed herein will provide new means and generate insights to phenomena occurring on the shortest timescales in nature. Past methods to probe ultrafast events – occurring on picosecond timescale or faster – have mostly relied on pump/probe scanning, yet these can only measure the dynamics of such processes if they are repetitive. Understanding all spatiotemporal aspects of ultrafast phenomena, however, requires experimental means to spatially, spectrally and temporally resolve them. Recently the PI invented a “coding” imaging concept called Frequency Recognition Algorithm for Multiple Exposures (FRAME) that can film at up to 5 trillion frames per second. To date, FRAME is the only videography method that can unify a femtosecond temporal resolution with spectroscopic compatibility, making it a powerful tool with high potential for new scientific discoveries. This project aims to (i) develop novel diagnostic tools based on FRAME and (ii) apply FRAME videography to study ultrafast events, whose temporal evolution could not be visualized in the past. Ultrafast science is a wide field, making the project highly interdisciplinary. For example, within photo-physics, systems will be developed to film plasmas and laser filaments. Diagnostics will be developed to image the lifetime of coherent states as well as fluorescence decays of two fluorophores in parallel, which holds potential within biology, physics and chemistry. A two-color FRAME setup will be developed to temporally track the creation and consumption of two species in a chemical reaction simultaneously. The ensemble of work-packages proposed herein constitutes a significant step forward in the research area of ultrafast imaging and videography.";1998792;1998792;ERC-2018-STG;/ERC-STG;LUNDS UNIVERSITET;SE;;;;1;0;0;1;0;0 217980;813599;TRIM-NET;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2018;H2020;Training network in drug discovery targeting TRIM Ubiquitin ligases in disease;2019-01-01;2022-12-31;;"The TRIM-NET innovative training programme will provide Early-Stage Researchers with the skills to identify novel therapeutic targets and develop the strategies to validate them in preclinical studies. Integrating complementary expertise and multidisciplinary approaches TRIM-NET aims to address this goal, focussing on the Tripartite motif (TRIM) family of Ubiquitin E3 ligases, which plays an important role in many physiological processes. The importance of the role of TRIM proteins in these processes is underpinned by their recognised involvement in many disease processes such as cancer, neurodegeneration and rare genetic diseases. As such, they are excellent targets for therapeutic manipulation. The TRIM-NET consortium created a critical mass with complementary and interdisciplinary expertise, from Life Science to Chemistry, around this family of proteins to identify and exploit common targeting strategies for translational applications. The consortium is designed to train a cohort of researchers in skills and expertise essential for biomedical research in the era of personalised medicine, focussing on determining how: i) TRIM proteins contribute to disease; ii) to develop strategies to modulate TRIM proteins activity; iii) to design high throughput screening assays for drug discovery. The training programme comprises 7 highly integrated work packages: 4 scientific and 3 dedicated to training, dissemination and management. The proposal consists of 12 individual research projects that will form the basis of the research training aspects for the ESR recruited to the programme. As the scientific work packages are highly integrated, recruited ESRs will avail of techniques and training opportunities, including secondments, across the work packages. Through a unique international partnership between academic and non-academic partners the TRIM-NET training programme will provide ESRs with skills that are essential for future biomedical research in industry and academia.";3203448,48;3203448,48;H2020-MSCA-ITN-2018;/MSCA-ITN-ETN;UNIVERSITA DEGLI STUDI DI TRIESTE;IT;"ACADEMISCH ZIEKENHUIS LEIDEN;FONDAZIONE CASA SOLLIEVO DELLA SOFFERENZA;UNIVERSITY OF DUNDEE;AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS;KARLSRUHER INSTITUT FUER TECHNOLOGIE;STICHTING HET NEDERLANDS KANKER INSTITUUT-ANTONI VAN LEEUWENHOEK ZIEKENHUIS;INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS";"NL;IT;UK;ES;DE;FR";;1;0;0;1;0;0 218414;812772;Phys2BioMed;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2018;H2020;Biomechanics in health and disease: advanced physical tools for innovative early diagnosis;2019-01-01;2022-12-31;;"Phys2BioMed will offer excellent interdisciplinary and cross-sectoral training to a team of motivated early stage researchers (ESRs) on the application of cutting-edge physical tools for the mechanical phenotyping of cells and tissues of clinical relevance, aiming at developing novel early-diagnostic tools. The Phys2BioMed network will merge diverse competences at European level, from different fields like nanoscience and nanotechnology, physics, biology, and medicine, and will expose ESRs to the non academic and private sector. A key element of the project is the peer-to-peer collaboration of research academic institutions with industries and world-leading medical and clinical centers; these are the main actors of the global challenge against diseases, and within Phys2BioMed they will highlight unmet clinical needs, and actively cooperate with academic colleagues for developing novel diagnostic strategies. ESRs will be trained-through-research by world-leading junior and senior PIs, and will benefit of lecture courses, dedicated international schools and workshops, and topical conferences. Secondments to other nodes of the network will represent the main and more effective channel of dissemination and cross-fertilization of competences, ideas, and knowledge within the network. Besides training talented young scientists, ready to work at the boundary of diverse disciplines in the field of nanomedicine, Phys2BioMed will provide scientific and technological outcomes on biomechanics, and the mechanical determinants of diseases. Technology-wise, it will define standardized procedures for nanomechanical measurements, and the definition of the main features of new-generation instrumentation optimized for the mechanical phenotyping of clinical specimens. In the longer-term, Phys2BioMed will provide the platform and know-how to build a data bank of mechanical fingerprints of diseases, setting the ground for the development of effective early-diagnostic tools.";3911782,68;3911782,68;H2020-MSCA-ITN-2018;/MSCA-ITN-ETN;UNIVERSITA DEGLI STUDI DI MILANO;IT;"WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER;INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE;COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES;THE HENRYK NIEWODNICZANSKI INSTITUTE OF NUCLEAR PHYSICS, POLISH ACADEMY OF SCIENCES;FUNDACIO INSTITUT DE BIOENGINYERIA DE CATALUNYA;UNIVERSITAET BREMEN;OSPEDALE SAN RAFFAELE SRL;OPTICS11 BV;CENTRE HOSPITALIER UNIVERSITAIRE DE GRENOBLE;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS";"DE;FR;PL;ES;IT;NL";;1;0;0;1;0;0 218218;802891;LINKS;SIGNED;H2020-EU.1.1.;ERC-2018-STG;H2020;Kick-starting global cLimate Investments:uncovering hidden liNks in climate finance and exploring dynamic evolution of investment networKs for policy deSign;2019-09-01;2024-08-31;;"LINKS aims to contribute to a transformation of the climate finance system to deliver the scale and quality of investment needed to meet the Paris climate goals and ensure effective capital allocation. By understanding the architecture of the financial system, exploring macro patterns in low-carbon investment emerging from observed investors’ behaviour and interactions, and designing cross-cutting policies aligned with long-term climate targets, LINKS will promote essential guidance for a re-orientation of financial flows towards low-carbon and energy efficiency investments. LINKS aims to advance the understanding of the role of climate finance to foster the low-carbon transition by using network theory, advanced computational techniques and extensive empirical data to model the financial system as a complex adaptive system. LINKS will thus lay the foundations of, and pioneer a new field, namely climate finance networks, where dynamics of interconnected investors represented as a network, results in the complex behavior of the whole system. LINKS will bring together interdisciplinary theories and developments in finance, environmental economics, sociology, computer science, network analysis and complexity in an integrated approach to study and model climate finance. Taking this approach will allow advancements in at least three directions: i) a new theoretical approach to account for complexity thinking and systemic perspective in climate finance, ii) more empirical analyses on networks structures of low-carbon investments and their dynamics to shape the development of the climate finance system, iii) policy modelling analyses to explore whether specific architectures of the climate finance system have significant impact on the effectiveness of climate public policies and invested public resources. LINKS will thus deliver robust conclusions on how the financial system could contribute to the required investments to achieve the low-carbon transition.";1499956;1499956;ERC-2018-STG;/ERC-STG;UNIVERSITY COLLEGE LONDON;UK;;;;1;0;0;1;0;0 218073;821870;PROMETHEUS;SIGNED;H2020-EU.1.3.3.;MSCA-RISE-2018;H2020;PROtocols for information Models librariEs Tested on HEritage of Upper Kama Sites;2019-01-01;2021-12-31;;"PROMETHEUS objective is to implement an interdisciplinary action for the documentation and structuring of information about architectural heritage, boosting the training of researchers on the constructive and historical value of Cultural Heritage Routes. The research will develop innovative methodologies of digitisation of architecture with the integration of multidisciplinary data and Information Models, leading to specialised figures able to operate on heritage built assets. The definition of a “charta”, for the replicability of action, will be pursued with a practical action on the monuments present in Upper Kama route (Russia) as pilot case of study. The network of researchers from different sectors involved in the action favours/supports the cultural and thematic widening necessary to develop and show the skills that the market requires. The Italian expertise in digital survey of architectural heritage, the Spanish knowledge on building technology and census archives related to architecture, together with the historical and territorial planning knowledge provided by the Russian partner, will allow researchers to deal with professional companies that operate in the intervention fields of restoration projects and BIM Management. The research project will develop an information/cognitive 3D system, multidisciplinary and implementable, that represents the preparatory step for to the management, maintenance and valorisation of Cultural Heritage Routes over European committees and administrations. The system, in order to be widely applicable, will be Low cost and easy to replicate, and it will optimize an innovative channel of cooperation between researcher and professionals though the use of BIM Collaborative Protocols. Participants will exchange skills and knowledge that will allow them to progress in new methods of documentation and conservation, to strengthen collaborative research and to widen their career perspectives in European Heritage Preservation.";464600;391000;H2020-MSCA-RISE-2018;/MSCA-RISE;UNIVERSITA DEGLI STUDI DI PAVIA;IT;"SISMA - SISTEMI INTEGRATI DI MONITORAGGIO ARCHITETTONICO SRLS;UNIVERSITAT POLITECNICA DE VALENCIA;EBIME CONSULTORIA TECNICA SOCIEDADLIMITADA";"IT;ES";;1;0;0;1;0;0 218215;795658;MAFMA;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;MULTISCALE ANALYSIS OF FATIGUE IN Mg ALLOYS;2019-09-01;2021-08-31;;According to the Europe police (EV5V-CT94-0375) Magnesium alloys are potential metals to be progressively introduced in structural components in many areas, especially in transport to reduce weight and achieve required CO2 reductions. As the deformation and failure mechanisms of Mg alloys are very complicated owing to basal slip, prism slip, primed slip and twinning, there lack reliable continuum level constitutive models for engineering application. This project will solve one of the most challenging open questions of Mg alloys, i.e. the influence of twin formation and persistent slip bands on the fatigue crack nucleation and growth by using rigorously scale-bridged models and in-situ experiments. Molecular dynamics, dislocation dynamics, phase field, nonlocal crystal plasticity finite element as well as cohesive zone method will be used to study twin nucleation, twin growth, persistent slip band as well as fatigue crack, respectively. The outcome of this interdisciplinary research proposal will be published in high impact peer-reviewed journals and at international conferences. The approach and the code developed in this proposal will improve the predictive power of Integrated Computational Materials Engineering concerning Mg alloy industry. The applicant will transfer his expertise and his international connection in the field of multiscale modelling to the host institute. He will work with researchers of the host institution to prompt new areas of research that can attract new funding. At the same time, he will receive regular training on transferable skills. All these activities will enlarge the portfolio of skills of the applicant and will ensure further development of his career.;170121,6;170121,6;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;FUNDACION IMDEA MATERIALES;ES;;;;1;0;0;1;0;0 218209;823941;FUNGLASS;SIGNED;H2020-EU.1.3.3.;MSCA-RISE-2018;H2020;FUNctional GLASS;2019-01-01;2022-12-31;;"The scientific objective of the project FUNGLASS- FUNctional GLASS integration in photonic devices and components- addresses one of the most crucial challenges in research and innovation which lies in the design and manufacturing of optical components and systems. Among the materials used in photonic devices, glasses play a central role: they are used as laser sources, lenses, smart screen, optical fibers and specialty fibers to name a few. FUNGLASS breakthrough relies on the control of nano/micro processing and 3D printing of glass by laser writing or poling, offering extraordinary opportunities for fabrication of elementary building-blocks such as multimaterial optical fibers with unique topology, morphology and novel properties for the design of integrated multifunctional components and devices. FUNGLASS proposes interdisciplinary European scale staff exchange programme with unique positioning on laser/field 3D nano/micro patterning and functionalizing of novel photonic glass materials allowing fabrication of sophisticated components and systems on their own. The involvement of large international centers with state of the art facilities for developing photonics components will enable provision of the required skills for developing a career in the private sector, as an entrepreneur, a CEO, a chief of R&D department etc. The involvement of international experienced and recognized professors, ER, involved in the project will also ensure that ESRs are prepared for a career in research excellence. Moreover, the strong lasting links between those centers allow the popup for an unpreceded international network in photonics and material. This proposal will contribute to sustain this network by the creation of joint unit laboratory between participants.";938400;864800;H2020-MSCA-RISE-2018;/MSCA-RISE;UNIVERSITE DE BORDEAUX;FR;"FRIEDRICH-SCHILLER-UNIVERSITAT JENA;UNIVERSIDADE DE AVEIRO";"DE;PT";;1;0;0;1;0;0 218450;813863;BORGES;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2018;H2020;Biosensing with ORGanic ElectronicS;2019-01-01;2022-12-31;;"Organic Bioelectronics is a fast-rising field encompassing organic electronic devices that exhibit mixed electronic and ionic conductivity. It represents a truly unique communication bridge across the technology gap existing between the living systems and digital electronics. Biosensing is one of the most scientifically and industrially promising application of organic (bio)electronics. It is important to form young professionals that will be able to operate into this highly-interdisciplinary field, where proficiency in chemistry, materials science and technology, solid state physics, biochemistry, engineering is needed. Such curricula can be hardly constructed within institutional degrees, at least not at the level that can be provided by a European Training Network. The objective of BORGES is to train the next generation of R&D innovators in organic bioelectronics, with the aim of developing organic biosensors up to demonstration in an end-user significant context. BORGES trainees will be educated with a holistic perspective of the technology, from fundamentals and fabrication, through characterization, to clinical/research user scenarios. BORGES training will be based on i) acquiring solid background in different scientific and technological fields; ii) exposing trainees to diverse sectors, from academia to technological research centres to industrial nodes; iii) fostering the development of transversal competencies. The BORGES Network is composed by 12 beneficiary institutions and one associate partner. With 4 non-academic nodes, and research centres with a clear industrial drive, BORGES ensures exposure of its fellows to a truly multisectorial environment. The state of the art training received by its fellows in a rapidly growing field with a strong socio-economic impact will fully qualify them to access novel and highly qualified job positions, and to substantially increase their employability and career perspectives.";3979589,4;3979589,4;H2020-MSCA-ITN-2018;/MSCA-ITN-ETN;UNIVERSITA DEGLI STUDI DI MODENA E REGGIO EMILIA;IT;"LINKOPINGS UNIVERSITET;AIT AUSTRIAN INSTITUTE OF TECHNOLOGY GMBH;RISE ACREO AB;CULGI BV;KEYSIGHT TECHNOLOGIES GMBH;UNIVERSITE DE STRASBOURG;FUNDACIO INSTITUT DE BIOENGINYERIA DE CATALUNYA;ASSOCIATION POUR LA RECHERCHE ET LE DEVELOPPEMENT DES METHODES ET PROCESSUS INDUSTRIELS;SCRIBA NANOTECNOLOGIE SRL;ACONDICIONAMIENTO TARRASENSE ASSOCIACION;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV";"SE;AT;NL;FR;ES;IT;DE";;1;0;0;1;0;0 218008;777222;ATTRACT;SIGNED;H2020-EU.1.4.2.1.;INFRAINNOV-01-2017;H2020;breAkThrough innovaTion pRogrAmme for a pan-European Detection and Imaging eCosysTem;2018-08-01;2020-11-30;;The ATTRACT Phase-1 project proposes a new collaboration paradigm aligned with the ‘Open Science, Open Innovation and Open to the World’ philosophy. Its objective is the identification and initial development of breakthrough detection and imaging technology concepts for expanding fundamental research frontiers and suitable for future industrial upscaling for novel applications and business. It promotes the involvement of national and pan-European Research Infrastructures and their associated research communities, industrial organizations (especially SMEs) and innovation and business specialists. It proposes a co-innovation approach in which scientific and industrial communities jointly pursue and generate breakthrough concepts in close and equal partnership. The project implementation starts with the launch of an Open Call by the project consortium for €17 million of financial support to Third-Parties. The proposals received will be peer-reviewed by an Independent R&D&I Committee of top experts in the field of detection and imaging technologies. After this process 170 breakthrough technology concepts will receive €100,000 of seed funding each (“lump sum”) to develop the concepts further during one year. The funded projects will then present their results in a Final Assessment Conference in Brussels. The ATTRACT Phase-1 consortium members will provide business assessments to the funded project teams to enhance awareness of future commercial applications. Furthermore, two pilots based on design thinking methodologies will be run for/with interdisciplinary master level students, aimed at discovering and generating social value applications inspired by the technologies of the funded projects. The ATTRACT Phase-1 project consortium comprises top partners capable of catalysing a large variety of key stakeholders towards a future unique European innovation ecosystem. The project will take 28 months to complete.;19999072,5;19999072,5;H2020-INFRAINNOV-2017-1;/RIA;EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH;CH;"INSTITUT MAX VON LAUE - PAUL LANGEVIN;EUROPEAN MOLECULAR BIOLOGY LABORATORY;EUROPEAN SYNCHROTRON RADIATION FACILITY;EUROPEAN SOUTHERN OBSERVATORY - ESO EUROPEAN ORGANISATION FOR ASTRONOMICAL RESEARCH IN THE SOUTHERN HEMISPHERE;FUNDACION ESADE;AALTO KORKEAKOULUSAATIO SR;EIRMA EUROPE AISBL;EUROPEAN X-RAY FREE-ELECTRON LASERFACILITY GMBH";"FR;DE;ES;FI;BE";;1;0;0;1;0;0 218150;791122;Tips in SCQFT;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Lattice gauge theories studies of timely theoretical and phenomenological questions in strongly coupled quantum field theories.;2019-04-01;2021-03-31;;"'As a MSC fellow I will work on the investigation of non-perturbative and topological properties of strong interactions and beyond. This project includes the study of 3 timely problems on Strongly Coupled Quantum Field Theories (SCQFT) using Lattice techniques. Within this project I will provide the detailed calculation of the spectrum of the closed flux-tube in 4-dimensional Yang-Mills theory and investigate the properties of the new 'axion' particle on the worldsheet of the QCD flux-tube. This includes the extraction of the excitation spectrum of the flux-tube in the fundamental representation of colour with N-ality k=1 as well as in representations with k=0 and k=2, for short as well as long-flux tubes and for arbitrary values of the ?-vacuum angle. Furthermore, I will evaluate the Standard Model value of the neutron Electric Dipole Moment (nEDM) via Lattice QCD; this investigation would make use of 3 and 4 flavours of quarks with masses corresponding to the physical pion mass as well as an extrapolation to the continuum. This would provide valuable input for current and future experiments measuring nEDM. In addition I will investigate strongly coupled BSM physics as a possible explanation for the mechanism of electroweak symmetry breaking. Within this framework I will study the continuum properties of the SU(2) Yang-Mills theory with 1 adjoint Dirac flavour. This might proved to be an essential component of a theory that could realise the mechanism of electroweak symmetry breaking and could be verified by LHC or future experiments. This 3-fold interdisciplinary project requires computational work which involves highly sophisticated numerical techniques and state of the art HPC facilities. The above actions will be running in parallel with an estimated completion time of 24 months. Moreover this proposal aims to train the fellow on GPU programming, simulations at finite ?, BSM phenomenology and to introduce as well as to establish UNIPI in Lattice BSM studies.'";180277,2;180277,2;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;UNIVERSITA DI PISA;IT;;;;1;0;0;1;0;0 218396;812764;MOVES;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2018;H2020;Migration and Modernity: Historical and Cultural Challenges;2019-03-01;2023-02-28;;"Today’s world sees masses on the move: across the globe, there are almost one billion international and internal migrants; in the EU alone, there are 57 million residents living outside their country of birth, amounting to over 11% of the EU28 population. This unprecedented global situation requires serious political action. Yet this action will only be effective once the historical, cultural and social roots of migration are properly understood. It is this understanding that the ITN MOVES will provide. The project’s chief objective is to undertake a comparative study of the social and cultural roots of mass mobility, and provide the urgently needed historical analysis that can address the so-called migration crisis of the present through an understanding of the population movements of the past. The network has been set up as an interdisciplinary collaboration between researchers in the Humanities and the Social Sciences who will approach migration as both a condition of modernity and one of its greatest challenges, placing the systematic confrontation of past and present forms of migration at the centre of their activities. Through its innovative training programme, carried out in conjunction with 18 non-academic partners (including NGOs, charities, and the cultural and creative industries), MOVES will enable a new generation of experts gain the historical knowledge required to respond to future migration crises with innovative solutions. The project will generate new knowledge about the shaping of the modern world and provide conceptual tools to avoid short-termism in migration management through its emphasis on enduring cultural patterns, historical context, and migration flows over the long term. The links between contemporary and historical migration that MOVES research will uncover can be used to improve educational provision, inform future policy, and counter the rise of anti-immigrant sentiment across the EU.";3910064,4;3910064,4;H2020-MSCA-ITN-2018;/MSCA-ITN-EJD;UNIVERZITA KARLOVA;CZ;"UNIVERSITE MONTPELLIER III PAUL VALERY;UNIVERSITY OF KENT;UNIVERSIDADE DO PORTO;FREIE UNIVERSITAET BERLIN";"FR;UK;PT;DE";;1;0;0;1;0;0 218138;813192;ElectroPros;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2018;H2020;Training research pioneers by utilizing and validating the promise of electroporation for minimal invasive oncological treatments.;2019-01-01;2022-12-31;;"The ElectroPros action aims to optimally prepare young researchers for the evolving technology in the healthcare space, especially related to minimal invasive oncology therapies, by offering a unique set of targeted interdisciplinary training and research assignments in the areas of biophysics modelling and simulation, device physics, optimization algorithms, software integration and experimental validation. Four European Industrial Doctorate positions are offered to Early Stage Researchers (ESRs) for a period of three years. In the training program a combination of industrial, academic and clinical research environments are provided by Philips, the University Clinic Aachen and RWTH Aachen, to explore the field of electroporation, as a new and promising technique for minimal invasive oncology treatment. Based on sound career development plans, and coached by experienced supervisors, the four ESRs involved will develop a competence profile which will springboard their future career in the wide European medical community in the industrial, clinical and academic domain. These researchers have the potential to become pioneers for new minimally-invasive therapies for the oncology domain. During their training, the ESRs will work on electroporation based treatment of cancer. The ESRs address shortcomings of the currently available equipment to enable for the first time ever a reliable patient-specific electroporation based treatment for cancer. With a focus on liver cancer, the ESRs will collectively establish novel insights on the biophysical effects on various tissues, important to understand the treatment effect, and integrate this knowledge in optimal device (needle) design and multi-physics models for treatment outcome prediction and inverse planning algorithms. Furthermore, the developed assets will be integrated in clinical prototype software to support and optimize the clinical workflow.";1023985,08;1023985,08;H2020-MSCA-ITN-2018;/MSCA-ITN-EID;PHILIPS ELECTRONICS NEDERLAND B.V.;NL;UNIVERSITAETSKLINIKUM AACHEN;DE;;1;0;0;1;0;0 218125;793811;PICVOLC;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;DePICting the interior of active VOLCanoes to reduce volcanic hazards: application to the present unrest at Nevado del Ruiz (Colombia) - PICVOLC;2019-02-01;2021-01-31;;"More than 500 million people live within the range of volcanoes whose activity can have disastrous economic and environmental impact. Being able to infer changes in the magmatic system during volcanic unrest is important for improving hazard preparedness and forecast future eruptions. PICVOLC aims to overcome the limitations in the current approach in the modeling of volcanic unrest by developing a new, original methodology that integrates seismic, gravity, and deformation data with 3D numerical inversion to create a detailed representation of the source of volcanic unrest. The current volcanic unrest at Nevado del Ruiz volcano will be the case study used to implement, calibrate, and verify this original approach. In 1985, a lahar generated by a modest eruption of Ruiz completely destroyed the town of Armero, killing 25,000 people. PICVOLC involves the integration of fieldwork with Finite Element Methods modeling and joint numerical inversions of geodetic and geophysical data. PICVOLC´s multi-/interdisciplinary nature aims to better constrain the conceptual and numerical models of volcanic unrest and reduce the ambiguity in the identification of the location, depth, volume change, and nature of the source of unrest. The project involves national and international collaboration; it is academic but has also important implications for the monitoring and reduction of volcanic hazards at Ruiz. In particular, it will provide the following innovative products: (a) definition of the subsurface structures with a new map of Bouguer anomalies; (b) 3D FEM model of the volcano; (c) 3D Image of the source(s) of volcanic unrest from inversion of geodetic data; (d) training of graduate students and the staff of the local volcano observatory in numerical modeling. Finally, PICVOLC will be a key step in achieving my professional maturity by extending and reinforcing my knowledge and skills in the design of, involvement in, and management of an international research project.";168277,2;168277,2;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;UNIVERSITA DEGLI STUDI DI ROMA LA SAPIENZA;IT;;;;1;0;0;1;0;0 218442;812580;SULTAN;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2018;H2020;European Training Network for the remediation and reprocessing of sulfidic miningwaste sites;2018-09-01;2022-08-31;;For more than 100 years the EU mining industries have been discarding their extractive-waste residues. Estimates suggest this represents 29% of the EU-28’s current waste output. When poorly managed these residues are a significant environmental hazard. Sulfidic Cu-Zn, Zn-Pb and Cu-Zn-Pb tailings pose the largest challenge, as they are prone to acid mine drainage. However, these tailings also contain valuable metals. Recently, the EIP Raw Materials launched a “call to arms” to transform the “extractive-waste problem” into a “resource-recovery opportunity”. Additionally, the EIP has warned about the acute shortage of talent in this sector. In order to develop a highly skilled work force, to mitigate environmental risks and to economically recover valuable raw materials, the ETN for the remediation and reprocessing of sulfidic mining waste sites (SULTAN) provides the first-ever training programme dedicated to the reprocessing of tailings. SULTAN has pooled the interdisciplinary and intersectoral expertise of leading EIT RawMaterials members, world-leading mining and chemical companies, covering all links in the tailings-reprocessing value chain. SULTAN develops cutting-edge methodologies to assess the resource potential of Europe’s main tailings families (WP1) and explores eco-friendly mining chemicals for advanced metal-extraction/recovery set-ups (WP2). SULTAN not only recovers the metals but also valorises the clean(ed) tailing residues in circular-economy applications, incl. inorganic polymers, green cements and ceramics (WP3). In WP4 a novel environmental assessment methodology is developed. The 15 SULTAN ESRs benefit from a unique soft-skills training programme (WP5) and maximise the impact of their research through dissemination & exploitation (WP6). This kick-starts their careers as highly employable professionals in the EU’s tailings reprocessing/remediation sector, as well as for geological surveys, teaching and scientific organisations, and public bodies.;3910958,64;3910958,64;H2020-MSCA-ITN-2018;/MSCA-ITN-ETN;KATHOLIEKE UNIVERSITEIT LEUVEN;BE;"VLAAMSE INSTELLING VOOR TECHNOLOGISCH ONDERZOEK N.V.;FCIENCIAS.ID - ASSOCIACAO PARA A INVESTIGACAO E DESENVOLVIMENTO DE CIENCIAS;WIENERBERGER NV;OULUN YLIOPISTO;TECHNISCHE UNIVERSITAT CLAUSTHAL;EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH;HELMHOLTZ-ZENTRUM DRESDEN-ROSSENDORF EV";"BE;PT;FI;DE;CH";;1;0;0;1;0;0 218306;813928;INNOVATEDIGNITY;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2018;H2020;Training the next generation of leaders to deliver innovations in dignified sustainable care systems for older people;2019-01-01;2022-12-31;;"INNOVATEDIGNITY is a trans-national network that aims to deliver a shared, world-leading research and training programme to educate the next generation of thought leaders with the necessary research experience and transferable skills to deliver innovations in dignified, sustainable care systems for older people, including new care models and digital applications. INNOVATEDIGNITY’s research examines older peoples' perspectives of care systems with a specific focus on dignity, investigates the potential for digital applications, and analyses gender issues to provide crucial, urgently needed knowledge for sustainable and fit for purpose care that supports older people to live well. The network's programme of investigation: 1) Critically evaluates existing care systems and provide analyses that make use of older persons’ insights. 2) Examines and offers a range of conceptual, empirical and methodological conditions to develop new innovations, including digital technology that offer dignity in care. 3) Provides an analysis of impacts of new care models on the wellbeing of older people. 4) Critically examines impacts of gender on care delivery, on the leadership of caring and science careers, and the care workforce with insights for sustainability. INNOVATEDIGNITY addresses the European problem of how ageing people can live well in caring systems with a concentration on cross-disciplinary scholarship, producing an evidence base through fifteen PhD projects, interlinked with a series of integrated assignments, and supported by a coherent interdisciplinary training. INNOVATEDIGNITY will produce leaders well versed in innovating care from standpoints within and beyond ‘healthcare’, sectors that engage technology, the public, policy makers for the benefit of older people in Europe beyond the consortium nations.";4330277,28;4330277,28;H2020-MSCA-ITN-2018;/MSCA-ITN-ETN;UNIVERSITY OF BRIGHTON;UK;"LINNEUNIVERSITETET;AARHUS UNIVERSITET;DIOIKISI 6IS YGEIONOMIKIS PERIFEREIAS PELOPONNISOU IONION NYSON IPEIROU KAI DYTIKIS ELLADAS;BIRMINGHAM CITY UNIVERSITY;TECHNOLOGIKO EKPEDEFTIKO IDRYMA IPIROU;HOEGSKOLAN I BORAS;BOURNEMOUTH UNIVERSITY;NORD UNIVERSITET;AALBORG UNIVERSITET";"SE;DK;EL;UK;NO";;1;0;0;1;0;0 194840;653241;OMNICS;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Observing, Modelling and Predicting in situ Petrophysical Parameter Evolution in a Geologic Carbon Storage System;2016-03-10;2018-03-09;;Geologic Carbon Storage (GCS) is a promising remedial activity that society can use to tackle imminent problems from increased atmospheric CO2 and climate change. The fate and transport of the stored CO2 are controlled by a storage formation’s petrophysical parameters, which evolve rapidly after the CO2 injection because of geochemical reactions. Knowing how the pore structure evolves is critical to the safe and effective implementation of GCS because it affects the sealing integrity, injectivity and storage capacity of a geologic site. How such evolution can be quantified is still unknown, because of the technological difficulties in direct observation within pores and the high computational cost required to predict such evolution based on current modelling approaches. My project will pioneer the study of GCS-related petrophysical parameter evolution by combining synchrotron based nanotomography with a highly customizable reactor network model. Tomography enables the in situ observation of the porous media’s morphological evolution that leads to petrophysical property changes. The reactor network model can significantly reduce computational costs for predicting parameter evolution. OMNICS builds on a combination of my expertise in GCS-related research and chemical reactor design with my host’s world leading nanostructure characterization facilities and cutting edge interdisciplinary research profile. Strong industry links provided by my host means that my new prediction technique will provide direct guidance for site selection, risk assessment and injection management, pushing the technological readiness level of GCS from applied research towards market relevant implementation as a technical support service. Meanwhile, the training, mentoring and support offered by my advisor, Prof. S. Stipp, will broaden my expertise, sharpen my competences and extend my research network, which will help me secure a academic position in Europe by fully realizing my potential.;200194,8;200194,8;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;KOBENHAVNS UNIVERSITET;DK;;;;1;0;0;1;0;0 217994;812865;DELIVER;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2018;H2020;DELIVERy of advanced therapies for diabetes training network;2019-01-01;2022-12-31;;The DELIVER EID programme aims to equip 6 industrial PhD graduates with all of the tools required to become creative, entrepreneurial and innovative leaders in the emerging European advanced therapies sector. Advanced therapies are new medicinal products based on genes or cells and tissue engineering products (biomaterials), sometimes used in combination with medical devices. They herald revolutionary treatments for a number of chronic diseases including Alzheimer’s, cancer and the focus of the DELIVER programme, Diabetes Mellitus. We aim to DELIVER the next cohort of translational research scientists in the field of advanced therapies and enabling medical devices for pancreatic islet transplantation, a cell therapy which is poised to become more widespread for the treatment of insulin-dependent diabetes. The DELIVER doctoral training network therefore represents a major interdisciplinary effort between cell biologists, experts in biomaterials, medical devices and advanced drug delivery, clinical experts in islet transplantation and research-active biotech and biomedical companies. Each DELIVER early stage researcher (ESR) will tailor a Personal Career Development Plan (PCDP) to ensure that over the course of the programme the core research skills, advanced research skills and intersectoral transferable skills for a successful career in the advanced therapies sector are acquired. Intersectoral transferable skills training will focus on enhancing career opportunities and employability of the trainees by developing their innovative and entrepreneurial capacity, their communication and leadership skills and their commercial awareness. This will result in graduates with all the skills necessary to innovate, develop and translate advanced therapies for diabetes for the benefit of European patients and industry.;1577944,8;1577944,8;H2020-MSCA-ITN-2018;/MSCA-ITN-EID;NATIONAL UNIVERSITY OF IRELAND GALWAY;IE;"EXPLORA SRL;EBERHARD KARLS UNIVERSITAET TUEBINGEN";"IT;DE";;1;0;0;1;0;0 218267;801770;ANGULON;SIGNED;H2020-EU.1.1.;ERC-2018-STG;H2020;Angulon: physics and applications of a new quasiparticle;2019-02-01;2024-01-31;;"This project aims to develop a universal approach to angular momentum in quantum many-body systems based on the angulon quasiparticle recently discovered by the PI. We will establish a general theory of angulons in and out of equilibrium, and apply it to a variety of experimentally studied problems, ranging from chemical dynamics in solvents to solid-state systems (e.g. angular momentum transfer in the Einstein-de Haas effect and ultrafast magnetism). The concept of angular momentum is ubiquitous across physics, whether one deals with nuclear collisions, chemical reactions, or formation of galaxies. In the microscopic world, quantum rotations are described by non-commuting operators. This makes the angular momentum theory extremely involved, even for systems consisting of only a few interacting particles, such as gas-phase atoms or molecules. Furthermore, in most experiments the behavior of quantum particles is inevitably altered by a many-body environment of some kind. For example, molecular rotation – and therefore reactivity – depends on the presence of a solvent, electronic angular momentum in solids is coupled to lattice phonons, highly excited atomic levels can be perturbed by a surrounding ultracold gas. If approached in a brute-force fashion, understanding angular momentum in such systems is an impossible task, since a macroscopic number of particles is involved. Recently, the PI and his team have shown that this challenge can be met by introducing a new quasiparticle – the angulon. In 2017, the PI has demonstrated the existence of angulons by comparing his theory with 20 years of measurements on molecules rotating in superfluids. Most importantly, the angulon concept allows one to gain analytical insights inaccessible to the state-of-the-art techniques of condensed matter and chemical physics. The angulon approach holds the promise of opening up a new interdisciplinary research area with applications reaching far beyond what is proposed here.";1499588;1499588;ERC-2018-STG;/ERC-STG;Institute of Science and Technology Austria;AT;;;;1;0;0;1;0;0 217941;812673;OrganoVIR;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2018;H2020;Organoids for Virus Research - An innovative training-ETN programme;2019-01-01;2022-12-31;;"OrganoVIR (Organoids for Virus Research) will train young researchers (ESRs) in the field of organoids and virology. Human viral infection studies lack suitable experimental models as animal models or conventional 2-dimensional (2D) cell cultures do not translate to human infection. OrganoVIR makes use of the breakthrough in the culturing of primary human cells into 3D cultures (organoids). Within this ETN programme, organoids will be used for the first time to study human viral infections in their natural environment. OrganoVIR includes leading partners in virology and organoid technology covering 7 academic institutes, 3 life science companies, 1 organoid technology private company, 2 non-profit organisations, a national public health institute and a business school originating from 8 countries. The aim is to introduce and establish human organoids as superior models for viral pathogenesis studies and antiviral testing, thus replacing animal models and reducing animal use. OrganoVIR provides a full package ETN programme for ESRs to learn the science of innovative 3D culture systems for virus research as well as financial, commercial, ethical, communicative, policy and dissemination aspects for optimal valorization. The projects are intensified by significant secondments at commercial, governmental and non-profit partner institutes. OrganoVIR provides: - High-ranked scientific and technical training in an interdisciplinary, intersectoral and international top research project - Training in transferrable managerial skills, including a pre-MBA - Implementation of innovative organoid technology for viral pathogenesis studies and antiviral development - Innovation in organoid technology by co-culture design and high throughput screening. OrganoVIR combines frontier research with an innovative training programme in a complementary network, certifying high impact scientists.";3983591,88;3983591,88;H2020-MSCA-ITN-2018;/MSCA-ITN-ETN;Academisch Medisch Centrum bij de Universiteit van Amsterdam;NL;"CHARLES RIVER NEDERLAND BV;UNIVERSITE CLERMONT AUVERGNE;UNIVERSITE DE GENEVE;STEMCELL TECHNOLOGIES UK LTD;DANMARKS TEKNISKE UNIVERSITET;UNIVERSITEIT UTRECHT;KATHOLIEKE UNIVERSITEIT LEUVEN;UNIVERSITEIT VAN AMSTERDAM;UNIWERSYTET JAGIELLONSKI";"NL;FR;CH;UK;DK;BE;PL";;1;0;0;1;0;0 218205;814276;WON;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2018;H2020;Wideband Optical Networks;2019-01-01;2022-12-31;;"The annual global Internet traffic will 127-fold increase from 2005 to 2021, with a Compound Annual Growth Rate of 24% from 2016 - 2021. In the context of such extraordinary traffic growth, we are proposing the Wideband Optical Networks (WON) European Training Network, to promote international, inter-sectorial and multi/inter-disciplinary research activities and career development. WON will train 14 early-stage researchers (ESRs) in the area of wideband optical networks through collaboration of 14 academic and industrial highly qualified institutions. Solutions identified within WON will enable to overcome a possible traffic-crunch by achieving a 10-fold increase in the usable optical bandwidth of single-mode fibres. Being highly multidisciplinary, WON will cover all topics and expertise from design and development of photonic components, novel digital signal processing algorithms and system modelling to network and control management. WON is a doctoral-level training network that will benefit of rich interactions between the academia and industry. Eight academic and six industrial partners from nine different European countries will constitute the consortium The ESRs will benefit from a comprehensive training programme featuring inter-sectorial and multidisciplinary technical courses, rich transferable skills training and international inter-sectorial secondments with a strong focus on industrial experience. WON ESRs will be capable of leading interdisciplinary research activities with unique expertise on designing physical-layer-aware wideband optical communication networks. In this context, the WON training networks will serve as a European platform for outstanding doctoral training in the field of ultra-high capacity next generation optical networks.";3706317,72;3706317,72;H2020-MSCA-ITN-2018;/MSCA-ITN-ETN;ASTON UNIVERSITY;UK;"CORIANT PORTUGAL UNIPESSOAL LDA;UNIVERSITEIT GENT;FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.;CORIANT R&D GMBH;POLITECNICO DI TORINO;DANMARKS TEKNISKE UNIVERSITET;UNIVERSITY OF PELOPONNESE;TECHNISCHE UNIVERSITEIT EINDHOVEN;VPIPHOTONICS GMBH";"PT;BE;DE;IT;DK;EL;NL";;1;0;0;1;0;0 195935;660378;HOOKaWORM;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2014-GF;H2020;Hook a Worm to Catch a Man: Tracking Historical and Recent Human Settlement, Land use and Migration in Neotropical Rainforests using Ecosystem Engineers;2015-05-01;2018-04-30;;"The anthropologic and archaeological study of pre-Columbian people of the Amazonian basin has revealed sophisticated agriculture practices. Notwithstanding the absence of historical written records the biological evidence of these practices remains in the remarkable biodiversity of the Amazonian 'dark earths' (ADEs) or “Terra Preta do Indio” produced by ancient civilisations to promote highly productive and sustainable agriculture. Promoting the interdisciplinary connection between anthropology, soil ecology and genomics the applicant will be able to investigate both the relationship of ADEs to the associated extant biodiversity, reveal details of past and current anthropogenic impact on the natural surroundings, as well as new clues regarding settlement dynamics over a large part of Brazil. The applicant and the supporting team will accomplish this by: a) Assessing the current soil biodiversity assemblages to gain knowledge about the functioning and potential role of soil ecosystem engineers, organic matter and nutrients to the formation of these extremely fertile soils; this novel approach will aid in understanding the origin and sustainable management of ADEs as well as highly weathered and acid soils under humid tropical conditions. b) Using DNA barcoding to describe the diversity of the ecosystem engineer community associated with past and recent Amerindian settlements throughout the Amazonian basin. c) Using genomics of a peregrine species closely related with human landscape domestication to mirror the human exchanges and flow among the Neotropical rainforest associated with the migration of Amazonian Indians. This will be achieved by integrating the state-of-the-art methods in invertebrate morphology, molecular genetics, and computational analyses with incorporation of pre-existent and new ecological, anthropological and environmental metadata sustained by a multidisciplinary collaborative network.";261599,4;261599,4;H2020-MSCA-IF-2014;/MSCA-IF-GF;CARDIFF UNIVERSITY;UK;;;;1;0;0;1;0;0 195410;657223;EWTEK;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2014-GF;H2020;Empowering Women with Traditional Ecological Knowledge;2015-07-01;2018-05-31;;"In rural Morocco, women are the gatekeepers of Traditional Ecological Knowledge (TEK) linked to natural resource management.Women have been underestimated for their important contribution to producing and securing food, managing natural resources, and their ability to earn an income through these activities. Even though massive aid budgets from the major donors, including the European Union, are allocated to expand Morocco’s programmes to combat poverty, social exclusion and gender inequality, rural women are still poorly integrated in Moroccan society. Using an original interdisciplinary approach of ethnobiology, development studies and geography, this study will explore whether women are able to gain social status and economic development through applying their traditional ecological knowledge in the context of the Green Morocco Plan in two rural communes of Rhamna Province. The study will cover the two main issues: 1) an analysis of the socio-historical, political context of the country, to assess the interests and motives of the Moroccan government to address gender issues; 2), an ethnographic investigation into women’s traditional knowledge activities looking in particular at the transfer of women’s traditional knowledge and environmental practices to new income generating activities. The policy relevance of the study lies in its aim to ensure that a gender aware ‘rural traditional dimension’ is included in programme policies with concrete proposals on how to overcome rural women’s socio-economic stagnation, and improve the working conditions of rural women in Morocco. It will contribute to the current debate of gender analysis, environmental practices and women’s integration in development programmes. The Fellowship is expected to deliver a curriculum to expand this new field of enquiry to resolve issues of social exclusion. It will open up perspectives of employment for the researcher in a European academic institution or a policy research institute.";236257,7;236257,7;H2020-MSCA-IF-2014;/MSCA-IF-GF;ERASMUS UNIVERSITEIT ROTTERDAM;NL;;;;1;0;0;1;0;0 217558;757565;GLOBESCAPE;SIGNED;H2020-EU.1.1.;ERC-2017-STG;H2020;Enabling transformation: Linking design and land system science to foster place-making in peri-urban landscapes under increasing globalization;2018-06-01;2023-05-31;;"Unprecedented urbanization is threatening landscape diversity, bringing along new social and environmental problems. Standardized business centers, single family residential areas and shopping malls displace highly productive agricultural land, while the culture and lifestyles of local communities become absorbed into the sphere of globalization. This dramatic uniformisation is nurtured by the ever increasing global human migration. People are losing their sense of place and their motivation to initiate change. Uniformed international landscapes start dominating peri-urban areas. The result is a tremendous increase in fragility of these new landscapes of the twenty-first century, calling for an active and creative landscape shaping process to secure the long-term provision of critical ecosystem services. Up until now, however, models and tools developed in land system science have not caught up with the needs to understand and ultimately foster humans’ capacities to shape their landscapes. This project will contribute to a next generation of tools and methods to foster the development of resilient landscapes. I suggest linking design and probabilistic modeling in a collaborative landscape development tool to enable the transformation of spaces into places. This unconventional approach is necessary to deal with the probabilistic nature of landscapes. Landscapes can only be defined by including the observer – a concept severally neglected in today’s research efforts. Anchored in four peri-urban case studies, the interdisciplinary experimental and modeling work will have impact far beyond predicting transformation pathways of peri-urban landscapes under increased globalization. The resulting methods and tool will redefine the status quo of current geodesign tools, promote novel ways of deliberative decision-making and governance, and ultimately support humans to intentionally transform peri-urban landscapes.";1498106;1498106;ERC-2017-STG;/ERC-STG;EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH;CH;;;;1;0;0;1;0;0 217522;771383;Global Horizons;SIGNED;H2020-EU.1.1.;ERC-2017-COG;H2020;Global Horizons in Pre-Modern Art;2018-09-01;2023-08-31;;"The horizon is the line that seems to separate earth from sky, the line that divides all visible categories into two categories: those that intersect the earth’s surface and those that do not. The horizon is key to the experience of space; it defines our perspective on the visible world. The GLOBAL HORIZONS project will investigate the historical meanings and functions of the horizon in visual and intellectual cultures of the pre-Modern world on a global scale. Examining how pre-Modern cultures conceived of the horizon opens a crucial line of inquiry into understanding the many different ways in which humans have conceived of the relationship between an invisible cosmos and the visible world. Non-western art history is rarely taught at European institutions although countless important works of Non-Western art are kept in museum collections all across Europe. Including non-western concepts of pictorial space is key to the project, however, for Eurocentric models of art history have generally privileged the rise of the linear perspective. This framing has limited our understanding of the horizon’s complex rhetorical, visual and epistemological roles. The project’s specific question connects a variety of objects and epistemological categories, such as panel painting, manuscript illumination, profane und religious objects, cartography, travel accounts, and cosmological treaties. The applied methodological approaches will range from art history, visual studies and cultural anthropology. They will also draw upon interdisciplinary expertise, such as technologies of art production, history of science and philosophy. The project thus makes an important contribution to global art history, a highly innovative area in which only very few pre-modern topics have been addressed. It is the ultimate goal of GLOBAL HORIZONS is to suggest a new history of representation in Western medieval art.";1904188;1904188;ERC-2017-COG;/ERC-COG;UNIVERSITAET BERN;CH;;;;1;0;0;1;0;0 217534;796045;SIKB;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;The Development of Students' Identities as Knowledge Builders;2018-09-01;2020-08-31;;"This fellowship addresses the vital societal and educational challenge of preparing school students to successfully take part in the new knowledge society. The research component will examine students’ identities as knowledge builders as they study human body systems and climate change within fifth-grade classrooms designed as knowledge building communities. The objectives of the research address both theory and practice, aiming to (a) elucidate a conceptual framework on how boys' and girls' identities as knowledge builders grow over time; and (b) impact school implementation by articulating research-based design principles that enhance the development of students’ identities as knowledge builders. By introducing the notion of identity to knowledge building, I will bring together humanistic psychology and the learning sciences, leading to interdisciplinary advancements and practical knowledge about how to design sustainable learning communities using collaborative learning technologies. The outgoing and incoming phases of this fellowship entail close mentoring with two outstanding researchers, both of whom are directors of prestigious national research centres, to serve as supervisors. Together with formal training activities, the engagement of the supervisors in educational innovation created through research-practice partnerships will provide me with an ideal environment for my research goals to actualize. Aided by six short visits during the course of the fellowship with leading international scholars on knowledge building communities, I will create a consortium for European researcher-practice partnerships focused on implementing knowledge building communities, making a vital contribution to the 'Innovation Union'. Altogether, this fellowship will develop my career as an international leader in learning community research and design aiming to address a key societal and educational challenge of the innovation age.";177319,8;177319,8;H2020-MSCA-IF-2017;/MSCA-IF-GF;UNIVERSITY OF HAIFA;IL;;;;1;0;0;1;0;0 217590;764553;AIRCOAT;SIGNED;H2020-EU.3.4.;MG-2.1-2017;H2020;Air Induced friction Reducing ship COATing;2018-05-01;2021-04-30;;"The overall goal of AIRCOAT is to make European waterborne transport more energy efficient and less polluting by developing a disruptive hull coating that reduces the frictional resistance of ships. The AIRCOAT project will enhance a passive air lubrication technology that utilises the biomimetic Salvinia effect. This effect enables trapping air through combination of a hydrophobic micro-structured surface with hydrophilic pins. The project will technologically implement this effect on a self-adhesive foil system. Applying a ship with such an AIRCOAT foil will produce a thin permanent air layer, which reduces the overall frictional resistance while acting as a physical barrier between water and hull surface. Besides substantially reducing main engine fuel oil consumption and hence exhaust gas emission, the air barrier further inhibits the attachment of fouling, the release of biocide substances (of underlying coatings) to the water and mitigates the radiation of ship noise. As a refit technology, it is immediately applicable to the whole fleet, is independent of the fuel type and can be combined with other efficiency improving technologies. Consequently, the technology creates both an economical and an environmental benefit. The interdisciplinary AIRCOAT consortium will develop small-scale prototypes to optimise the surface characteristics of this new technology supported by experimental and numerical methods. AIRCOAT will further produce large-scale pilots to demonstrate the efficiency and industrial feasibility in operational environments (laboratory, research ships and container ship). Finally, the project will perform a full-scale validation process to boost the technology towards market readiness. The AIRCOAT project will demonstrate the high potential of this game-changing technology to revolutionise the maritime coating sector and to become a ground-breaking future energy efficiency and emission reduction technology.";5901541,25;5299097,38;H2020-MG-2017-Two-Stages;/IA;FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.;DE;"HAMBURGISCHE SCHIFFBAU-VERSUCHSANSTALT GMBH;PPG COATINGS EUROPE BV;DANAOS SHIPPING COMPANY LIMITED;KARLSRUHER INSTITUT FUER TECHNOLOGIE;AQUABIOTECH LIMITED;AVERY DENNISON MATERIALS BELGIUM;ILMATIETEEN LAITOS;HOCHSCHULE BREMEN;REVOLVE WATER";"DE;NL;CY;MT;BE;FI";;1;0;0;1;0;0 212649;751581;VHDD;TERMINATED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Computer-aided Van der Waal Heterostructure Device Design using Unique Response to Electric Fields;2018-11-20;2020-11-19;;The van der Waals heterostructure has been a central focus of materials research and nanotechnology for a decade. It is because this heterostructure can provide device platform highly flexible for materials combination. Thanks to those advantages, this heterostructure system is highlighted for potential application for flexible and low-power consumption electronics. In this research proposal, we will propose new device architecture using novel 2D physics under an electric field. Because of its low-dimensional nature and transparency of electric field, the band structure at the heterostructure can be remarkably modulated. Our objective is to design new device architecture using this phenomenon. To achieve it, we will find out best heterostructure using high-throughput calculations and will design the device architecture. Then, we will simulate the device characteristics using DFT-NEGF method and validate it experimentally. This approach is pioneering for coming up with new device architecture, which will open a new direction beyond the state-of-the-art. Thanks to its novelty, it is expected to have a high impact in the fields of physics, materials science, and nanoelectronics. Through this research project, the applicant will obtain valuable opportunity for career development and will promote interdisciplinary nature of this research field.;187866;187866;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN;IE;;;;1;0;0;1;0;0 216571;788793;BACKUP;SIGNED;H2020-EU.1.1.;ERC-2017-ADG;H2020;Unveiling the relationship between brain connectivity and function by integrated photonics;2018-11-01;2023-10-31;;"I will address the fundamental question of which is the role of neuron activity and plasticity in information elaboration and storage in the brain. I, together with an interdisciplinary team, will develop a hybrid neuro-morphic computing platform. Integrated photonic circuits will be interfaced to both electronic circuits and neuronal circuits (in vitro experiments) to emulate brain functions and develop schemes able to supplement (backup) neuronal functions. The photonic network is based on massive reconfigurable matrices of nonlinear nodes formed by microring resonators, which enter in regime of self-pulsing and chaos by positive optical feedback. These networks resemble human brain. I will push this analogy further by interfacing the photonic network with neurons making hybrid network. By using optogenetics, I will control the synaptic strengthen-ing and the neuron activity. Deep learning algorithms will model the biological network functionality, initial-ly within a separate artificial network and, then, in an integrated hybrid artificial-biological network. My project aims at: 1. Developing a photonic integrated reservoir-computing network (RCN); 2. Developing dynamic memories in photonic integrated circuits using RCN; 3. Developing hybrid interfaces between a neuronal network and a photonic integrated circuit; 4. Developing a hybrid electronic, photonic and biological network that computes jointly; 5. Addressing neuronal network activity by photonic RCN to simulate in vitro memory storage and retrieval; 6. Elaborating the signal from RCN and neuronal circuits in order to cope with plastic changes in pathologi-cal brain conditions such as amnesia and epilepsy. The long-term vision is that hybrid neuromorphic photonic networks will (a) clarify the way brain thinks, (b) compute beyond von Neumann, and (c) control and supplement specific neuronal functions.";2499825;2499825;ERC-2017-ADG;/ERC-ADG;UNIVERSITA DEGLI STUDI DI TRENTO;IT;;;;1;0;0;1;0;0 215031;791908;SURFInG;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;StructURal and Functional dynamics of BrassIca napus polyploid Genome;2018-05-19;2020-05-18;;"Interspecific hybridization and genome doubling (allopolyploidy) are key factors in plant adaptation and speciation. These intriguing genomic processes cause extensive structural rearrangements and reprogramming of functional regulatory pathways inherited from parental species. Furthermore, hybrid species have shown broad phenotypic diversity. However, mechanisms responsible for genome stabilization after allopolyploidy remain poorly understood. The aim of my project is to provide an interdisciplinary overview of the effects of polyploidy on structural and functional dynamics in a major crop, oilseed rape (Brassica napus). This polyploid species is an excellent system to unravel the long-term and immediate evolutionary effects of ancient and recent polyploid events. In my project, I will use a novel approach that combines (epi)genomics and transcriptomics in phenotypically contrasting polyploids to investigate the role of structural and (epi)genetic regulation in genome stabilization. This work includes, amongst others, the transfer of knowledge to the host lab of cutting-edge molecular and in silico DNA methylation analysis methods. More specifically, I will determine the effects of structural and functional dynamics on B. napus (1) meiotic behavior and fertility, (2) gene expression and (3) glucosinolate content. My findings will open new avenues for using standing variation to modify and ultimately enhance agronomic traits. I have become a recognized evolutionary biologist working at the interface of ecology, genomics and molecular biology. From the expertise of the host lab and availability of technical platforms in situ, I will not only get acquainted with cytogenetics and metabolomics, but will increase my expertise in comparative genomics and in high throughput genotyping analyses. I will also extend my network towards the private sector and be integrated into a well-established European community, positioning me on track to succeed academically in France.";185076;185076;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE;FR;;;;1;0;0;1;0;0 215489;796817;ARTEMIS;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Graphene Molecule Interfaces for Spintronics;2019-09-01;2021-08-31;;The future of our society is intimately bounded to the development of smaller, faster and cheaper technologies, which can promote the ability to read, store and manipulate data. Spintronics addresses the issue by encoding information into the spin degree of freedom of electrons, in alternative or in addition to the charge. Currently, the progress of spintronics depends on the engineering of new advanced materials, which can promote the injection and transmission of the spin of electrons into the condensed matter. ARTEMIS will tackle the problem through the fabrication and study of graphene/molecule hybrid interfaces, taking advantage of both the exceptional physical properties of graphene and the additional degrees of freedom provided by molecular complexes. ARTEMIS focuses on the design of graphene/molecule interfaces in which a selection of molecules deposited on the graphene film will allow the spin scattering mechanisms of the material to be probed and manipulated as a consequence of charge transfer and magnetic coupling effects. The interfaces will be incorporated into spin valve devices realized with state-of-the-art nanofabrication techniques, in order to characterize their properties as a function of external parameters, such as electric field, magnetic field, temperature and optical excitation. The data analysis will allow meaningful spin transport quantities, such as the spin relaxation time, spin relaxation length, spin-orbit-coupling strength and spin-to-voltage conversion ratio, to be extrapolated in order to determine the actual device performance and compare it to the behaviour of pristine graphene films. ARTEMIS will shine light on the spin transport mechanisms in graphene and test the benefits of adopting graphene/molecule interfaces as building blocks of competitive spin-based technologies. Finally, ARTEMIS will promote the career of a young female researcher with a hands-on training on a promising interdisciplinary field of physics.;158121,6;158121,6;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;Asociacion - Centro de Investigacion Cooperativa en Nanociencias - CIC NANOGUNE;ES;;;;1;0;0;1;0;0 215016;790615;FUNNANO;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Functional Nanoscale Imaging: New Techniques to Probe Living Cells;2018-06-18;2020-06-17;;This proposal presents unique and innovative approaches for ultra-high-resolution functional electrochemical imaging of living cells, using smart nanometer probes that will enable the investigation of bio-physicochemical process within a single living cell with unprecedented sub-cellular resolution. Truly nanoscale electrochemical probes will be developed that shall be capable of performing multiple in-situ and time-resolved electrochemical measurements, and synchronously map cell topography. This will bring a whole analyses laboratory onto a probe tip in a new conceptual idea of a “lab-on-a-tip”, which is at the core of this proposal. Using PC12 cells as an exemplar, we will investigate cellular uptake/release, cellular membrane charge heterogeneity (down to the single protein) and temperature gradients, as well as chemical and environmental aspects to respiration. The developments from this proposal will represent a major breakthrough in functional electrochemical imaging and will elucidate key cellular processes. This developments will have a huge impact on life sciences and on the electrochemical imaging field and, granted the wide applicability of electrochemical imaging, will be hugely beneficial for other areas of science. The proposal is highly interdisciplinary, and there is a natural fit between the Fellow’s profile and activities at the Host Group and collaborators in Life Sciences. The proposal draws on the Fellow’s solid background in chemistry and instrumentation development, which will be married with the world-leading research on new nanoscale functional imaging techniques of the Warwick Host. With support and expertise from the Host, this project will provide the applicant, Gabriel N. Meloni, with an outstanding opportunity to pioneer a new area of science, from which he will benefit in the future as he develops his independence. The project build and strengthen scientific links between the Gabriel’s home country (Brazil) and groups in Europe.;183454,8;183454,8;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;THE UNIVERSITY OF WARWICK;UK;;;;1;0;0;1;0;0 215635;798381;UPDWMI;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Ultra-low Power Digital circuits for Wireless Medical Implants;2018-06-15;2020-07-29;;Advances in nanotechnology have made it possible to implant ultra-small electronic sensors in the human body. Interfacing with organs and nervous system, these devices will be a key part of future healthcare technologies. One of the most important components in such a device is the electronic integrated circuit (IC) located right at the signal source. This determines the overall power consumption and size of an implant. However, due to the need for sensitive analog circuits and toxicity concerns, very advanced silicon technology nodes (as in consumer electronics) cannot be used in such ICs. Hence, the power & area consumption is of significant concern. The primary aim of the project is to develop custom, novel ultra-low power digital cells for efficient signal processing and communication circuits for miniature wireless medical implants. This goal fits ideally with the ongoing IMPACT project (in the same group) that aims to develop rice-grain size bio-electronic sensor to monitor cancer tumors. This project will be able to use custom digital cells to optimize this tradeoff between data compression and transmission bandwidth in such a device. The researcher will interact with a multidisciplinary team working on the IMPACT project, including IC designers, physicist, biochemist and clinicians. The highly interdisciplinary work will consider the limitations of such an implant in terms of its sensor functionality and physiological acceptance before deriving the electrical specifications. The researcher will bring her extensive experience in designing low-power CMOS arithmetic and memory circuits to this project. This will complement the existing knowhow in bio-sensors and high-performance sensor interfaces already being developed at the host group. She will receive training in multiple aspects of mixed-signal IC design, full-chip characterization and bio-electronic systems. The host organization will also benefit from her teaching and mentoring experiences.;195454,8;195454,8;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;THE UNIVERSITY OF EDINBURGH;UK;;;;1;0;0;1;0;0 214931;788752;UltraPal;SIGNED;H2020-EU.1.1.;ERC-2017-ADG;H2020;Ultimate Paleo-Ocean Records from Biogenic Calcites;2019-01-01;2023-12-31;;"The ambition with this proposal is to create ultimate paleo-environmental records for the oceans. This is a fundamental scientific challenge and the motivation is simple: The oceans take up 70% of the Earth’s surface area and represent an immense sink/source of, e.g., heat and CO2, which makes them key to the evolution of Earth’s climate. Assessing and understanding anthropogenic global climate change requires that role of the oceans is understood in detail. Proxies are needed to establish past ocean conditions with high accuracy. Calcite has played a fundamental role in these efforts because isotopic and trace element compositions of limestone and calcitic fossils are related to ocean conditions at the time of their formation. Geochemical studies of calcite in the ocean sediment record have therefore contributed enormously to the understanding of Earth’s climatic evolution over the last several hundred million years. However, our recent work (Bernard et al., Nature Communications, 2017) identifies a fundamental problem: Visually imperceptible, ultrastructure-level processes that occur during sediment diagenesis can introduce a very strong bias in these records, in particular those based on biogenic calcite; i.e., structures produced by living organisms such as foraminifera and brachiopods. Previously not investigated or taken into account, such ultrastructure-level diagenesis will (and does) create large errors in ocean paleo-environmental reconstructions, even under the close-to-ambient pressure and temperature conditions characterizing shallow sediment burial. This proposal offers a solution: An entirely new, interdisciplinary approach, including ultra-high-resolution isotopic imaging (NanoSIMS), is developed here to quantify these effects in a broad range of biogenic calcites, permitting genuinely non-biased, calcite-based paleo-ocean reconstructions to be created. The impact of this work on climate change research will be dramatic and immediate.";2435000;2435000;ERC-2017-ADG;/ERC-ADG;ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE;CH;;;;1;0;0;1;0;0 216006;769142;LOGISTAR;SIGNED;H2020-EU.3.4.;MG-5-2-2017;H2020;Enhanced data management techniques for real time logistics planning and scheduling;2018-06-01;2021-05-31;;"The EU faces the challenge to maintain and increase its economic growth and cope with the problem of freight transport efficiency in Europe. Integration of transport volumes and modes, better use of capacity, flexibility, resource efficiency and cooperation between all actors along the logistic chain are required. Aligned with the European policies and the ALICE roadmap, LOGISTAR objective is to allow effective planning and optimizing of transport operations in the supply chain by taking advantage of horizontal collaboration, relying on the increasingly real-time data gathered from the interconnected environment. For this, a real-time decision making tool and a real-time visualization tool of freight transport will be developed, with the purpose of delivering information and services to the various agents involved in the logistic supply chain, i.e. freight transport operators, their clients, industries and other stakeholders such as warehouse or infrastructure managers. LOGISTAR will address several advances beyond the State of the Art in the interdisciplinary field of the smart algorithms for data processing: Artificial Intelligence focussed onr prediction, parallel hybrid metaheuristics for optimization, automated negotiation techniques, and constraint satisfaction problem solving techniques. The resulting platform will outperform other market products and services such as Freight Exchange Systems, Collaborative Platforms, Transport Control Towers or Routing Systems. LOGISTARS involves RTD organisations (DEUSTO, UCC, CSIC), technology developers (DNET, SWC), consultancy firms (MDST, PRESTON), ICT services developers (SAG, DBH, GENEGIS) and stakeholders from different stages of the supply chain (AHLERS, ZAILOG, NESTLÉ, PLADIS, CODOGNOTTO). The duration of the project is estimated to be 36 months and has an approximate budget of 5 million euros.";4997548,75;4997548,75;H2020-MG-2017-Two-Stages;/RIA;UNIVERSIDAD DE LA IGLESIA DE DEUSTO ENTIDAD RELIGIOSA;ES;"UNITED BISCUITS (UK) LIMITED;MDS TRANSMODAL LIMITED;DRUSTVO ZA KONSALTING, RAZVOJ I IMPLEMENTACIJU INFORMACIONIH I KOMUNIKACIONIH TEHNOLOGIJA DUNAVNET DOO NOVI SAD;CODOGNOTTO ITALIA SPA;NESTLE UK LTD;SOFTWARE AG;GENEGIS GI SRL;PRESTON SOLUTIONS LIMITED;AHLERS BELGIUM NV;AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS;SEMANTIC WEB COMPANY GMBH;dbh Logistics IT AG;UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK;CONSORZIO ZAILOG";"UK;RS;IT;DE;BE;ES;AT;IE";;1;0;0;1;0;0 215108;792948;NELMA;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Nanoscale Electrochemistry on Light Metallic Alloys;2018-06-01;2020-05-31;;"This proposal presents unique approaches for the characterization of light metal (magnesium as an exemplar throughout) alloy interfaces at the nanoscale in aqueous media, through the implementation of innovative, quantitative high-resolution scanning electrochemical probe microscopy techniques. The overarching goal is to introduce new methodology that will enable a comprehensive understanding of the influence of nanoscale inhomogeneities in the dissolution of light metal alloys. The scientific scope of this project involves: (i) determining the behaviour of different individual single entities (such as grains, grain boundaries, inclusions) on the heterogeneous surfaces of Mg-based alloys at the nanoscale, isolated from the rest of the surface (ii); progressing to the visualization of interacting surface sites and associated reactive fluxes during alloy dissolution; and (iii) nanostructuring at the nanoscale, as a new way for the rational study of surface treatments to improve alloy durability, which are of fundamental and technological (e.g. structural application bodies, bioimplants, batteries etc.) importance. The research proposal is highly interdisciplinary, and there is a natural synergistic fit between the Fellow’s profile and activities at the Host Warwick group. The project brings together the considerable expertise of the Fellowship applicant in light metal alloys and corrosion with that of the Host group in frontier correlative electrochemical microscopy to create new approaches that will greatly advance this important field. With considerable support and world-class expertise from the Host group and its collaborators, this project will provide the applicant, Dr. Viacheslav Shkirskiy, with an outstanding opportunity to develop personally and professionally, by pioneering a new area of research in a new geographic location.";183454,8;183454,8;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;THE UNIVERSITY OF WARWICK;UK;;;;1;0;0;1;0;0 215551;797533;REGinTRAN;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Advanced manufacturing and the transition of regional economies: institutions, social regulation and development in Apulia and Lower Silesia;2018-11-01;2020-10-31;;"At a time of technological transition REGinTRAN aims to understand under which conditions advanced manufacturing might turn out to be a viable driver for sustaining the development of regions suffering from structural disadvantages. On the one hand, the literature on systems of advanced manufacturing has mostly concentrated on a few highly successful regions and established a clear-cut distinction between growing and declining regions. On the other hand, studies on the national models of capitalism have tended to adopt a deterministic account of the process of economic development yet overlooking the role of actors. The main innovative contribution of REGinTRAN will be to embrace a dynamical perspective of the study of regional trajectories by taking into consideration the hitherto unrealized potential of less developed territories. More precisely, the project will investigate the linkages between social actors’ mobilizations, patterns of state intervention and the opportunities and constraints offered by digital technologies for industrial transformation. This will contribute to produce new knowledge on the institutions and mechanisms that can foster (or hinder) a process of socio-economic transition. REGinTRAN will be based on an interdisciplinary approach building on comparative political economy, sociology of public action and regional and economic geography. Apulia and Lower Silesia will be investigated in depth through a systematic comparison using causal process tracing (1999-2016). A quantitative analysis of socio-economic indicators for less developed regions in Europe will complement the case-study analysis. The project will provide policy inputs on how to build a collective capacity of action by mobilizing unused resources and promoting inclusive growth. Different measures (workshops with students and professionals; one policy-brief) will be taken in order to disseminate results and stimulate a wider non-academic debate.";180277,2;180277,2;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;UNIVERSITA DEGLI STUDI DI FIRENZE;IT;;;;1;0;0;1;0;0 215587;798021;GEOBACTICON;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;The efficiency of bio-self-healing concrete within ground conditions;2018-11-01;2020-10-31;;"Concrete is the most used construction material worldwide for infrastructure projects. Due to deterioration, regular maintenance works are necessary to seal the concrete cracks and restore durability. In Europe, infrastructures such as tunnels and earth retaining walls alone cost approximately 5 billion EUR per year. Self-healing strategies (particularly bacterial-based self-healing) are regarded as a promising solution to reduce the high maintenance and repair cost of concrete infrastructures. It is believed if self-healing concrete had been used for all these structures, up to 120 million EUR could be saved annually on their maintenance. The research to date has tended to focus on the self-healing process in air or water environment. However, infrastructures (i.e. bridges, buildings, tunnels) are built on or in the ground, where part of their concrete structures are inevitably embedded in soil environment with all sorts of ground conditions such as different types of soil, saturation regimes, and chemical exposures. It is not clear if the process of self-healing is efficient within concrete elements exposed to such complicated ground conditions. The project aims to explore the efficiency of the bacterial-based self-healing (bio-hydrogels) in underground concrete structures. By using a novel interdisciplinary approach, the research combines state-of-the-art technologies applied in materials/concrete, geotechnical engineering, and microbiology to conduct a series of lab-scale experiments on mortar specimens incubated within various soil environments. Purpose-built experimental tools are used to investigate the effect of several factors including the type of soil, saturation regime and class of (chemical) exposures, on the bio-self-healing process. The outcomes of this research are highly relevant to the construction industry and the knowledge produced by the project will have an economic, financial and societal impact in EU and other regions.";195454,8;195454,8;H2020-MSCA-IF-2017;/MSCA-IF-EF-CAR;UNIVERSITY OF DERBY;UK;;;;1;0;0;1;0;0 215411;796007;HYPTEMPCELL;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Local hyperthermia cancer treatment studies using a new temperature-imaging-hyperthermia-microscopy instrument;2018-09-01;2020-08-31;;"The scientific aim of the project is to explore a new concept of magnetic hyperthermia treatment for cancer that gets closer to the ideal non-invasiveness & no-secondary-effects kind of treatment to become a primary choice for cancer therapy. Instead of the typical approach of massive tumor heating, this project takes the alternative route of local intracellular heating inducing cell apoptosis. For this purpose, the project will develop a new instrument for temperature_imaging-magnetic_induction_heatingµscopy. The temperature imaging system is a complete novelty and it is based on the use of molecular luminescent temperature probes embedded in magnetic and non-magnetic nanoparticles. The probe’s emission microscope image is transformed into high-resolution temperature images. This will be used to model the heat transfer processes inside a cell. Then, the effect of local magnetic heating on cell apoptosis processes will be studied, and the potential of this technique in cancer therapy will be evaluated. The researcher will contribute to the hosting group with his previous experience on synthesis, characterization and physical properties of luminescent, plasmonic and magnetic nanoparticles, and he will benefit with a more application-oriented research experience in the biomedical field, and will develop skills in new scientific areas, especially high-resolution luminescence thermometry, that will help him to set his personal research interests and career. He will also get clinical experience from contact with hospital oncologists. The researcher will be included in an interdisciplinary group with international connections that will widen his knowledge and contacts scope of his scientific career. He will also gain experience in other transversal skills, as he will be directly involved in the managing the project, student supervision, networking, dissemination and communication activities.";158121,6;158121,6;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS;ES;;;;1;0;0;1;0;0 215673;798821;PPOM-PTT;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;New Peptide-Polyoxometalate Hybrids for Antimicrobial Photothermal Therapy;2018-09-01;2020-08-31;;"Antimicrobial resistance is a global challenge which is threatening the life and health of people from every country and region. Basically, most of the chemical or biological interferences may cause resistance to some extent. Recently, photothermal therapy (PTT) is attracting increasing attentions in anticancer researches and bringing enormous impacts in our scientific community. Inspired by this progress, we plan to construct a new class of peptides-polyoxometalates (PPOMs) hybrids for antimicrobial photothermal therapy. We do believe that this project will create a new research orientation in the interdisciplinary boundary between POM chemistry, photothermal therapy and antimicrobial therapy. To this end, we propose a reasonable route divided into three steps: (i) developing a series of PPOMs by covalent or noncovalent linkage of three kinds of POMs and epsilon-poly-L-lysines with 10, 15, 20, 25, 30 repeating units; (ii) endowing PPOMs with photothermal capacities by chemical reduction and establishing a standard method for photothermal antimicrobial experiments based on PPOMs; (iii) evaluating their photothermal antimicrobial activity against non-resistant and ampicillin-resistant E. coli and exploring their potentials to tackle the antimicrobial resistance. This proposal is appropriate for both beneficiary and host. Ms. She has experience in POM synthesis, anticancer therapy and self-assembly, which will be vital in this research. Besides, the expertise in Cronin’s group involving POMs, peptides synthesis, antibacterial evaluation and material characterization will be crucial for this proposal. More importantly, this project will become one step further in the research direction of Cronin's group. To conclude, this project will exert a strong influence in the field of POM chemistry and antimicrobial research, and the bilateral success between host and beneficiary will be achieved.";195454,8;195454,8;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;UNIVERSITY OF GLASGOW;UK;;;;1;0;0;1;0;0 215170;793550;PLASTIC TERN;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;The evolutionary genetics of multidimensional plasticity in a wild seabird;2018-09-01;2020-08-31;;"PLASTIC TERN is an interdisciplinary project using an ecological and evolutionary framework to integrate the study of physiological, behavioural and life-history traits to elucidate multi-dimensional patterns of phenotypic plasticity in the wild. We will focus on the evolutionary genetics of plasticity in a natural population of a relatively long-lived seabird under long-term investigation, the common tern (Sterna hirundo). More specifically, we will investigate how genetic variation in, and selection on, plasticity are shaped by internal factors, such as age, and external factors, such as temperature, breeding density and food availability; we will be using multiple labile traits (annual number of fledglings, body mass and spatial colony use) and studying multiple levels of variation. The long-lived nature of our study species and the natural annual fluctuations of food availability, temperature and density that characterise the study area and population provide a unique opportunity to study plastic responses driven simultaneously by intrinsic factors, such as age, and/or ecological factors. Additionally, the exceptional dataset collected on this population allows us to study how selection (via annual survival and reproductive success, as well as Lifetime Reproductive Success) acts on the previously described plastic responses. Despite the explicit evolutionary relevance of the question, the consequences of environmental changes for the action of natural selection on plasticity have remained largely unexplored.";173076;173076;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FR;;;;1;0;0;1;0;0 215423;796193;TRANSIMAMS;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Spreading Whose Word? Transnational Imams, Religion and Politics in Turkey’s Mosques Abroad (France, UK, USA);2018-11-01;2021-10-31;;Since the early 2000s, Muslim Diasporas in Europe and the USA have raised a growing interest in the public and academic spheres. While building upon this interest, the proposed research aims to bring an original contribution to the field by adopting a transnational perspective that focuses on the religious policy of Turkey towards its diaspora. The study will concentrate on the imams sent to Europe and the USA to work in the mosques managed by the Turkish Directorate of Religious Affairs (Diyanet). The ethnographic study of these “transnational imams” aims to go beyond a state-centered analysis of Turkish religious policy abroad in terms of “soft power” or “religious diplomacy”. Instead, it proposes to evaluate the modalities and limits of this policy by concentrating on the training, motivations, mobility and achievements of these imams, as well as the ways they are perceived by different components of the Turkish diaspora, with special focus on France, the UK and the USA. The interdisciplinary approach at the crossroad of political science, sociology and anthropology will address the political and religious dimensions of the ideology conveyed by the Diyanet imams and question their impact on the Turkish communities settled abroad, in terms of religious practices, political affiliation, integration and possible radicalisation. The comparative perspective will take into account the history and social characteristics of these distinct Turkish diasporas and the different traditions of state/religion relationship in the three countries under study to analyse the strategies of the Diyanet and evaluate its results. Thus, by focusing on Turkey’s religious policy abroad, the proposed study aims to bring an original contribution on political Islam as a transnational ideology that mobilises state resources, religious establishments and local communities to spread a polymorphous political and religious discourse.;269857,8;269857,8;H2020-MSCA-IF-2017;/MSCA-IF-GF;LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE;UK;;;;1;0;0;1;0;0 216304;800242;EURJAZZ;CLOSED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;The Europeanisation of Jazz during the Interwar Period: Beyond National Narratives;2018-09-01;2020-08-31;;"EURJAZZ looks at the role played by music in the process of cultural europeanisation. It examines how a cultural product coming from outside Europe can become fully part of European culture and identity. Taking jazz as an example of such cultural expression, the project explores how its diffusion outside the United States (USA) led to the development of a unified European jazz world, which was distinctive and independent from the American one. Three aspects of europeanisation are examined in light of representative case studies, considered from a transnational and European perspective: self-affirmation; appropriations, individuation and differentiation from the USA; integration and cooperation. EURJAZZ also shows that these three elements played a critical role in the formation of the first European jazz institution: the European Jazz Federation (1968-1975). The project explores the role of music in shaping identities at European level. It takes the inherent interdisciplinary nature of musicology a stage further by designing a research and training plan with the aim of establishing research cooperation that is of mutual benefit to European and Anglophone scholarly traditions in the Humanities and Social Sciences. EURJAZZ is timely in building on recent research about national histories of jazz in Europe in order to initiate a change of scale in the study of the history of jazz. Besides, it tackles one major challenge of the H2020 programme: a better understanding of Europe’s cultural identity and heritage. It is timely in being implemented during the European Year of Cultural Heritage (2018) and on the 100th anniversary of the arrival of jazz in Europe. The dissemination and communication plans aim to contribute to these celebrations. EURJAZZ has strong societal relevance, at a time when Europe is facing the threat of partial disintegration and when current immigration raises questions about the capacity of Europe to assimilate non-European cultural products.";195454,8;195454,8;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;ROYAL NORTHERN COLLEGE OF MUSIC;UK;;;;1;0;0;1;0;0 215519;797188;TreEsilience;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Global patterns of intraspecific variation in tree resilience to drought;2018-05-01;2020-04-30;;Forests provide essential long-term ecosystem services, such as reducing carbon emission and biodiversity conservation, and consequently, are the focus of many conservation policies (i.e. Europe 2020 Strategy). Drought events associated with climate change reduce tree growth and prompt mortality episodes, impacting global and severely forest ecosystems. The ability of trees to resist and recover from drought (tree resilience) will be decisive to maintain the functioning of forest ecosystems. Measuring tree climate-growth relationship and resilience is thus key for predicting the effect of climate change. However, because different tree populations may have faced contrasting climatic conditions, the within-species response to climate change may differ geographically due to local adaptation. TreEsilience proposes using tree rings to investigate the role of local adaptation in determining intraspecific variation in tree resilience to drought. To date, such an intraspecific approach has never been pursued. In order to reach this ambitious goal, TreEsilience will use an interdisciplinary approach that combines dendrochronology, phylogenetic comparative methods and species distribution modelling, thus bringing tools from the spatial and evolutionary ecology to the study of forest management and conservation. The results will provide insights into novel strategies to improve forestry efficiency by identifying early signals of tree mortality, useful for forest practitioners, policy-makers and stakeholders in order to mitigate the detrimental effects of land degradation and desertification on human wellbeing due to climate change.;170121,6;170121,6;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS;ES;;;;1;0;0;1;0;0 216508;787181;AngioMature;SIGNED;H2020-EU.1.1.;ERC-2017-ADG;H2020;Mechanisms of vascular maturation and quiescence during development, homeostasis and aging;2018-08-01;2023-07-31;;Angiogenesis research has focused on the sprouting of new capillaries. The mechanisms of vessel maturation are much less well understood. Yet, the maintenance of a mature, quiescent, and organotypically-differentiated layer of endothelial cells (ECs) lining the inside of all blood vessels is vital for human health. The goal of ANGIOMATURE is to identify, validate, and implement novel mechanisms of vascular maturation and organotypic EC differentiation that are active during development, maintenance of vascular stability in adults, and undergo changes in aging. We recently identified previously unrecognized gene expression signatures of vascular maturation in a genome-wide screen of ECs isolated from newborn and adult mice. Epigenetic mechanisms were identified that control the EC transcriptome through gain and loss of DNA methylation as well as EC differentiation and signaling specification. These findings pave the way for groundbreaking novel opportunities to study vascular maturation. By characterizing functionally diverse types of blood vessels, including continuous ECs in lung and brain and sinusoidal ECs in liver and bone marrow, the ANGIOMATURE project will (1) determine up to single cell resolution the transcriptional and epigenetic program(s) of vascular maturation and organotypic differentiation during adolescence, (2) analyze the functional consequences of such program(s) in differentiated ECs and their adaptation to challenge, and (3) study changes of maturation and differentiation program(s) and vascular responses during aging. We will towards this end employ an interdisciplinary matrix of approaches involving omics, systems biology, conditional gene targeting, organoid cell culture, and experimental pathology to create a high-resolution structural and functional organotypic angioarchitectural map. The project will thereby yield transformative mechanistic insights into vital biological processes that are most important for human health and healthy aging.;2338918;2338918;ERC-2017-ADG;/ERC-ADG;RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG;DE;DEUTSCHES KREBSFORSCHUNGSZENTRUM HEIDELBERG;DE;;1;0;0;1;0;0 216583;789256;SUMMIT;SIGNED;H2020-EU.1.1.;ERC-2017-ADG;H2020;Stepping Up mRNA Mutanome Immunotherapy;2018-08-01;2023-07-31;;"Immunotherapy is expected to fundamentally change the treatment of cancer patients. Personalized vaccines eliciting immune responses against individual cancer mutations have moved into the spotlight. We have pioneered the field and moved ´cancer mutanome vaccines´ from a mere vision into a disruptive medical concept compatible with current standards of drug development and health care practice. Solving key scientific and technological challenges and building on extensive preclinical studies, we showed in a first-in-human trial potent tumor-directed immunity in every single vaccinated patient, and clinical activity of a novel mRNA-based mutanome vaccine. Given that mutations are a hallmark of cancer, mRNA mutanome vaccines are universal drugs the efficacy of which are unaffected by the cancer type. The aim of this proposal is to ignite the next wave of advancement by addressing four key constraints challenging a full clinical realization of such vaccines. We will address the scarcity of point mutations in many tumors by extending neoepitope discovery to the full spectrum of genetic aberrations. Cancers are heterogeneous and outgrowth of clones unaccounted for by the vaccine is an efficient escape mechanism. We will develop neoepitope prediction algorithms deciphering clonal heterogeneity to inform rational vaccine design and countermeasures against selection of target escape variants. Tumor cell resistance to vaccine-induced T cells due to antigen presentation defects will be addressed by developing strategies for mobilizing the full repertoire of immune effector mechanisms, including antibodies and NK cells. T-cell exhaustion will be tackled by vaccination protocols promoting long-lived memory responses and by combination treatments counteracting tumor-mediated immunosuppression. Finally, we will drive the seamless clinical translation of the scientific findings by close interdisciplinary collaboration with strong and established clinical and industrial partners.";2482500;2482500;ERC-2017-ADG;/ERC-ADG;TRON - TRANSLATIONALE ONKOLOGIE ANDER UNIVERSITATSMEDIZIN DER JOHANNES GUTENBERG-UNIVERSITAT MAINZ GEMEINNUTZIGE GMBH;DE;;;;1;0;0;1;0;0 217476;800236;SHoW;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;SHARED WORLDS: revealing prehistoric shared worlds along Europe´s Atlantic Façade;2019-01-01;2020-12-31;;The proposed project (SHoW) investigates the roles that landscapes, skylines and astronomy played in past peoples' lives in order to determine the cultural relatedness between people along Europe´s Atlantic Façade. Specifically, it investigates the types of visual-scapes people chose for the erection of their megalithic monuments within and across regions, that clearly seem to have some kind of related megalithic tradition, but which is not yet understood. Focusing on the periods of intensive monument building in prehistoric Iberia (c. 4500-2500 B.C.) and Britain (3100-900 B.C.), innovative 3D technology, along with interdisciplinary approaches already brought to bear on past projects by the candidate, will assist in the reconstruction of past visual worlds of the megalith builders of western Galicia and Scotland. These, plus the development and use of new approaches in geospatial techniques, 3D technology, statistical approaches and database management are key for the determination of the roles that landscapes, skylines and astronomy played in past peoples' lives. By investigating the role of the natural world, this project upholds and extends UNESCO’s Astronomy and World Heritage Thematic Initiative, for the project recognises that the way people observed the land and the sky in the past is a repository for people’s perception of their world. Understanding these things opens the way for a new consideration of shared tangible and intangible values in the past. In this way, this MSCA candidate will produce insights into some of the most iconic representations of cultural remembrance in Europe, revealing whether the reasons behind erecting megaliths were the same for people in different regions of Europe´s Atlantic Façade, and if not, what the differences might have been, and why. Ultimately, SHoW will reveal the degree to which the people in these regions possessed shared worlds.;158121,6;158121,6;H2020-MSCA-IF-2017;/MSCA-IF-EF-CAR;AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS;ES;;;;1;0;0;1;0;0 216951;794891;ArchFarm;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Revisiting funerary practices: A methodological approach to the study of funerary sequences and social organisation in the Neolithic Near East, integrating forensic experiments in archaeo-anthropology;2018-10-01;2021-09-30;;"ArchFarm aims to expand the methodological principles of funerary archaeology and apply this innovative approach to interpret Neolithic Near Eastern burials. Funerary practices provide a valuable insight into social organisation and ideology of past societies. A major deficiency is that the archaeological record only shows the final deposition of human remains. Funerary practices are not often considered as a dynamic process that consists of several stages over a length of time. In addition, a confident interpretation of funerary treatment before deposition is currently very difficult due to the lack of experimental research. In order to reconstruct the sequence of funerary actions, ArchFarm will develop and test a protocol for the identification of pre-depositional treatment such as different forms of mummification. During the outgoing phase, controlled and repetitive experiments of human body decay will be conducted at the Australian Body Farm, the only human decomposition facility in the world that is connected to an archaeological department and combines archaeological questions with forensic science. The new methods will then be applied to Neolithic Near Eastern burials which are known for body part manipulations such as skull removal. During the incoming phase, skeletal remains from several Neolithic Near Eastern sites will be analysed. The results will be combined with ethnological research to increase our understanding of social choices and ideology behind certain funerary actions. ArchFarm is an interdisciplinary study that will create methodological novelties relevant to several periods. Based on a combination of archaeo-anthropology, forensic science and ethno-archaeology, this study will produce a more holistic narrative of funerary practices. In addition, ArchFarm will create the opportunity for communication and outreach on the subject of ‘dying, death and mourning in past and present times’.";270918;270918;H2020-MSCA-IF-2017;/MSCA-IF-GF;UNIVERSITE DE BORDEAUX;FR;;;;1;0;0;1;0;0 217001;810775;DRAGON;SIGNED;H2020-EU.4.b.;WIDESPREAD-05-2017;H2020;Data Driven Precision Agriculture Services and Skill Acquisition;2018-10-01;2021-09-30;;"'Precision Agriculture (PA) is an evolving farming management strategy using digital technologies & techniques to monitor and optimise agricultural production processes. PA methods, harnessing data streams from satellites, mobile phones, Internet of Things (IoT) and technologies such as cloud computing and artificial intelligence, have the potential to increase quantity & quality of agricultural outputs while reducing input (water, energy, fertilisers, pesticides, etc.) and waste. One of the main challenges facing PA is a low rate of adoption of PA technologies & practices, especially concerning the 'big data in agriculture'. One of the reasons is the lack of skills for executing efficient communication and in turn fuel the adoption rate of the data-driven PA innovations. There is also a need to enhance scientific & technological (S&T) skills for executing sophisticated data analytics on multiscale/multisource agricultural data, addressing all classes of data source, environment/region/individual farm/individual animals/plants, in order to extract more accurate and impactful actionable information and knowledge from the combined data. DRAGON capacity-building strategy will enable expertise and skill transfer from Agri-EPI Centre, the UK and Wageningen University in the Netherlands to BIOS in order to enhance 1) BIOS’ researchers’ S&T capacity for performing multi-scale/multi-source data analyses; 2) BIOS’ researchers’ capability to communicate practical big data-related knowledge to various stakeholders across the supply chain and the non-scientific local communities. Specifically, this means that BIOS knowledge technologies research group, currently focused on data analytics only (science-driven research), will be enhanced through DRAGON into BIOS Knowledge & Innovation Group (KIG) concentrating on interdisciplinary innovation-driven R&D within a co-creation environment. Post DRAGON BIOS’ KIG will be competitive in the PA sector on European and Global levels. '";962750;962750;H2020-WIDESPREAD-05-2017-Twinning;/CSA;BIOSENSE INSTITUTE - RESEARCH AND DEVELOPMENT INSTITUTE FOR INFORMATION TECHNOLOGIES IN BIOSYSTEMS;RS;"AGRI-EPI CENTRE LIMITED;WAGENINGEN UNIVERSITY";"UK;NL";;1;0;0;1;0;0 216943;764860;TOBeATPAIN;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2017;H2020;Targeting neuroinflammation to combat pathological pain in neurodegenerative diseases and chronic pain syndromes;2018-08-01;2022-07-31;;Damage to the central (CNS) and peripheral (PNS) nervous systems causes altered perception of pain (pathological pain) which is a common feature of diseases that have high prevalence in the European Union. Both increases and decreases in the ability to perceive pain impair both performance at work and quality of life. Pathological pain in neurodegenerative diseases, musculoskeletal diseases and peripheral neuropathies is associated with neuroinflammation, the inflammatory process whereby non-neuronal (inflammatory and glia) cells interact with neurones by releasing molecules that modulate pain signalling. TOBeATPAIN suggest that neuroinflammation represents an underlying mechanism of pathological pain states encompassing those with a PNS or CNS origin. The focus of this ITN will be on the mechanisms by which non-neuronal cells impact on neuronal activity in order to identify innovative non-neuronal targets for the treatment of pathological pain in peripheral macrophages or CNS microglia/astrocytes. TOBeATPAIN delivers high-level scientific and innovation-oriented complementary training, forging career pathways to increase inter-sectorial and transnational employability of young entrepreneurially-minded scientists in the academic and industrial sectors. It combines the expertise of 5 leading academic institutions, 2 pharmaceutical companies and 1 SME as Beneficiaries, together with 2 SMEs and 1 non-profit research charity as Partner Organisations, from 4 European countries. Fully aligned with the ‘Knowledge Triangle’ (business, research, higher education) platform, eleven ESRs will gain valuable knowledge and multidisciplinary skills through interdisciplinary research projects that integrate state-of-the-art technologies, supervision by and secondments to industrial Network organisations, Network-wide and local training activities, and specialized transferable skills focused in the acquisition of the ‘3-Knowledges’ (K-creation, K-exploitation, K-communication).;2870359,2;2870359,2;H2020-MSCA-ITN-2017;/MSCA-ITN-ETN;KING'S COLLEGE LONDON;UK;"UNIVERSITAETSKLINIKUM WUERZBURG - KLINIKUM DER BAYERISCHEN JULIUS-MAXIMILIANS-UNIVERSITAT;KANCERA AB;BIONORICA RESEARCH GMBH;MEDIZINISCHE UNIVERSITAT INNSBRUCK;KAROLINSKA INSTITUTET;Eli Lilly and Company Limited;Universitätsklinikum Jena";"DE;SE;AT;UK";;1;0;0;1;0;0 214010;799037;SmallDrugRheuma;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Discovery of Immune Therapeutic Targets and Immunomodulators for the Development of Novel Therapies in Rheumatoid Arthritis.;2018-06-29;2020-06-28;;Rheumatoid Arthritis (RA) is an autoimmune chronic disease, characterized by inflammation in multiple joints, ultimately leading to joint deformity, pain and swelling. RA is one of the most frequent inflammatory arthropathies, with a prevalence of 0.3%-1%, striking during the most productive years of adulthood, and is a chronic disabling condition. No therapies exist to prevent RA, and a high percentage of patients do not respond to currently available therapies. Our research aims to integrate expertise on immunology and cutting-edge screening technologies to identify novel immunotherapeutics for RA based on immune modulation mechanisms. The project makes use of an extensive screening effort using a chemical library (60,000 compounds) containing repurposing drugs (drugs already approved for their use for the treatment of other diseases), targeted libraries and lead-like compounds. The aim of the project is to identify novel small molecules capable to modulate the immune response, counterbalancing the altered inflammatory environment that characterizes RA. Elucidation of the mechanism of action of the candidates (cell type, pathway and target) will take place through state-of-the art technologies such as chemoproteomics, RNASeq or CRISPR/Cas9. Ultimately, the most promising candidates will be tested ex vivo in cells from RA patients, providing a proof-of-concept of the therapeutic utility of the identified mechanism. The project is interdisciplinary and will make progress beyond the state of the art, as the identified immunotherapeutics could also be employed to treat other (auto)immune diseases, as well as being potentially translated to immunotherapy of cancer and cardiovascular diseases. The high-quality and originality of this proposal will open up the best career possibilities for the experienced researcher, and will be carried out under the umbrella of a public-private partnership with a pharmaceutical company, boosting European competitiveness.;170121,6;170121,6;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;UNIVERSIDAD DE SANTIAGO DE COMPOSTELA;ES;;;;1;0;0;1;0;0 214293;774499;GoJelly;SIGNED;H2020-EU.3.2.5.;BG-07-2017;H2020;GoJelly - A gelatinous solution to plastic pollution;2018-01-01;2021-12-31;;'The objective of the GoJelly project is to develop, test and promote a gelatinous solution to microplastic pollution by developing a TRL 5-6 prototype microplastics filter (GoJelly) for commercial and public use, where the main raw material is jellyfish mucus. In doing so, the consortium addresses two environmental issues with one approach by removing the commercially and ecologically destructive sea and coastal pollution of both jellyfish and microplastics. This innovative approach will ultimately lead to less plastic in the ocean, municipal demand (and thereby competitive prices) for jellyfish raw material to fill the 'mucus-need' by filter developers, and in turn more jobs for commercial fishers in off-seasons. The by-products of the GoJelly biomass have other uses as well, ensuring that GoJelly also delivers a green innovation, resulting in novel, valuable resource for the food and feed industry as well as agro-biological fertilizer for organic farming. The GoJelly prototype products will be tested and demonstrated in three different European seas (Norwegian, Baltic and Mediterranean), by a range of stakeholders, including commercial fishers and industry partners. Tying it together, the project will also ensure the possibilities for broader European promotion and utilization of GoJelly at the local, regional and global level by delivering a socio-ecological methodological toolbox for forming and implementing policies. GoJelly will broadly communicate its results in several formats such as traditional social media, open lab ship cruise, and in the form of an experimental online game depicting different management scenarios under different jellyfish- and microplastics combinations. An interdisciplinary and international consortium consisting of technology developers, business analysts, fishing companies, research institutes, and both natural and social scientists will realize GoJelly, and will ensure the uptake of GoJelly products by industry and policy makers.';6222816,5;5998114,75;H2020-BG-2017-1;/IA;HELMHOLTZ ZENTRUM FUR OZEANFORSCHUNG KIEL;DE;"CRM COASTAL RESEARCH AND MANAGEMENT GESELLSCHAFT FUR KUSTENFORSCHUNG UND MANAGEMENT MIT HAFTUNGSBESCHRANKUNG GBR;UNIVERSITY OF HAIFA;UNIVERSITAET HAMBURG;SINTEF OCEAN AS;NACIONALNI INSTITUT ZA BIOLOGIJO;FONDATION EUROPEENNE DE LA SCIENCE;CHRISTIAN-ALBRECHTS-UNIVERSITAET ZU KIEL;HANSEATISCHE UMWELT CAM GMBH;CONSIGLIO NAZIONALE DELLE RICERCHE;ORT BRAUDE COLLEGE;SANPIETRO SOCIETA COOPERATIVA AGRICOLA;INSTITUTE OF OCEANOLOGY, CHINESE ACADEMY OF SCIENCES;ARDITI - AGENCIA REGIONAL PARA O DESENVOLVIMENTO DA INVESTIGACAO, TECNOLOGIA E INOVACAO - ASSOCIACAO;NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU";"DE;IL;NO;SI;FR;IT;CN;PT";;1;0;0;1;0;0 214115;792815;FemTHEATRE;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Through Her Own Looking Glass: Rethinking ‘Woman’ in Italian Feminist Dramaturgy;2018-09-03;2020-09-02;;Adopting an interdisciplinary approach that combines feminist theory, Italian Studies, and women’s writing for theatre, this project will offer the first full-length investigation of the entwined dynamics between the rise of active feminism in 1970s Italy and the coeval theatrical practice. The twofold research objective represents a novelty with respect to the scant existing criticism on the subject. The study will 1) look at how the dramaturgical served as an ideological vehicle for feminism in rethinking the representation of women’s gender roles and 2) assess the impact of feminist ideology in rupturing established dramatic conventions. To better achieve this scope, it will be articulated on three main grounds: i) contextualisation of feminist theory and practice in Italy ii) philological and theatrical analysis of a wide-ranging corpus of plays produced at the time iii) collection of first-hand testimonies. This project will benefit from a unique blend of competences between the researcher and internationally established experts from the Departments of Italian Studies and Theatre Studies at the University of Milan that, combined with intense training, will allow the researcher to reach a position of professional maturity. While promising to make a significant contribution to academia by developing new knowledge in the field, the project also recognises the importance of the research topic for a wider audience. Particular attention will be given to dissemination and audience development activities, including the realisation of a number of performances intended to raise awareness of feminist issues and the topicality of feminist matters nowadays among theatre audiences and the general public. Whilst focusing on the Italian context, this study will also fill a vacuum in Women’s and Gender Studies by establishing a connection between a historically circumscribed form of artistic output and its sociological and historical context that is hitherto lacking.;168277,2;168277,2;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;UNIVERSITA DEGLI STUDI DI MILANO;IT;;;;1;0;0;1;0;0 196019;660954;BBP;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Bridging Belief and Practice;2015-09-28;2018-03-20;;The aim of the proposed research is to bridge the gap between theoretical and empirical studies of religion, which up till now developed separately, as the studies of beliefs and the studies of practices. This will be done by means of elucidating the properties of beliefs and their relation to human embodied religious practices. . I decided to take the best of empirical investigations (phenomenology and the most prominent results of religious studies) and the best of theoretical investigation (analytic philosophy) and make a conceptual work to bridge them. As a methodological basis for this work I have chosen embodied approaches, as they present a link between phenomenological descriptions and strict analytical conceptualizations. Body is a medium between beliefs and practices, thus the concept of belief will be developed in relation to the practice with a body as a focal point and a key source of conceptualizations. The results of the research will be presented in clear-cut analytical terms, easy to use not only by empirical and theoretical researchers of religion, but also by participants of interreligious dialogue, thus contributing to mutual understanding and religious tolerance. I aim to provide a proper, detailed and accurate account of the properties of beliefs in their relation to practice by conceptualizing the results of empirical studies in clear-cut analytical terms. This project is an important step in my professional development, as for its fulfillment I will have to apply all my previous knowledge and interdisciplinary skills, and learn new analytic methods.;195454,8;195454,8;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;THE UNIVERSITY OF BIRMINGHAM;UK;;;;1;0;0;1;0;0 195047;655067;SHARE;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Shared Emotions, Group Membership, and Empathy;2016-04-01;2018-03-31;;"What is the relation between empathy, our ability to experience and understand others, and emotional sharing? How do shared emotions and group membership affect or bias empathy? And can groups collectively perform, or be targets of empathy? As the first multi-level approach to the topic, the project SHARE will address this set of questions in relation to one another. It will integrate hitherto unrelated philosophical traditions, research strands and state-of-the-art empirical methods (phenomenology, social ontology, as well as social cognition research and social neuroscience). SHARE aims not only at a better understanding of the role of emotions in interpersonal and intergroup encounters. The project’s distinctively philosophical take will also allow for a systematic re-assessment of empirical data from the social neurosciences, and yield conceptual adjustments that challenge standard literature. Regarding its yet broader socio-cultural impact, the project will contribute to research on group membership induced biases, such as research on racism, intercultural differences in emotional behaviour, or 'emotional dialects', and the 'politics' of affective identity-building. I will significantly profit from the exceptional scientific resources of the host institution, the Center for Subjectivity Research (CFS) at the University of Copenhagen. CFS’s highly interdisciplinary research environment neatly dovetails with the project’s working hypotheses. CFS’s exceptionally wide research network, as well as the unique expertise of its director and my supervisor, Prof. Dan Zahavi, in both cutting-edge research on phenomenology of sociality, social cognition, and empathy, and in large-scale research management, will guarantee a timely implementation of the project, and promote my professional maturity. Thus, a two-year MSCA-fellowship will re-enforce my status as an independent scholar, ready to assume a permanent a position at a European university.";200194,8;200194,8;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;KOBENHAVNS UNIVERSITET;DK;;;;1;0;0;1;0;0 210097;754397;DOC-FAM;SIGNED;H2020-EU.1.3.4.;MSCA-COFUND-2016;H2020;DOCtoral training programme in Functional Advanced Materials;2017-09-01;2022-08-31;;DOC-FAM is a COFUND Doctoral Programme with a duration of 60 months presented by the Spanish National Research Council (CSIC) and coordinated through the Institute of Materials Science of Barcelona (ICMAB). The main aim of the programme is the training of 22 early-stage researchers during 36 months each as the next-generation of scientists in the exciting field of Functional Advanced Materials, while at the same time offering a complete training experience to the recruited fellows. This doctoral programme builds up on the recent award obtained by ICMAB as one of the 22 “Severo Ochoa Centres of Excellence”, an award given by the Spanish Government that recognizes institutions from all areas of knowledge that perform cutting-edge research at world standards. The award as “Severo Ochoa Centre of Excellence” to develop “Smart Functional Materials for Social Grand Challenges” (FUNMAT, 2016-2019) demonstrates the outstanding international scientific leadership of ICMAB in the field of Advanced Functional Materials and Nanomaterials. The aim of the research programme offered in DOC-FAM is to complement the training aspects of FUNMAT by offering the recruited fellows an excellence training programme in the bourgeoning field of Functional Advanced Materials through an interdisciplinary, intersectorial and international approach with the support of several partner organisations from the area, four of them contributing to the co-funding of the doctoral programme. The designed training programme combines different types of activities that will enhance their research and personal skills, providing them with new career perspectives.;3453120;1726560;H2020-MSCA-COFUND-2016;/MSCA-COFUND-DP;AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS;ES;;;;1;0;0;1;0;0 198159;640254;MetAGEn;SIGNED;H2020-EU.1.1.;ERC-StG-2014;H2020;Metabolic and Genetic Regulation of Ageing;2015-08-01;2020-07-31;;"Ageing is a complex physiological process that affects almost all species, including humans. Despite its importance for all of us, the biology of ageing is insufficiently understood. To uncover the molecular underpinnings of ageing, I propose an interdisciplinary research program that will identify and investigate metabolic and genetic regulators of ageing. Progressive loss of cellular homeostasis causes ageing and an age-associated decline in protein quality control has been implicated in numerous diseases, including neurodegeneration. Seeking for ways to improve protein quality, I have identified a novel longevity pathway in Caenorhabditis elegans. In a forward genetic screen, I found a link between metabolites in the hexosamine pathway and cellular protein quality control. Hexosamine pathway activation extends C. elegans lifespan, suggesting modulation of ageing by endogenous molecules. In a first step, I will explore the mechanism by which hexosamine metabolites improve protein quality control in mammals, using cultured mammalian cells and a mouse model for neurodegeneration. Preliminary data show that hexosamine pathway metabolites enhance proteolytic capacity in cells and reduce protein aggregation, suggesting conservation. Second, I will investigate molecular mechanisms that activate the hexosamine pathway to promote protein homeostasis and counter ageing. Third, I will perform a direct forward genetic screen for modulators of ageing in C. elegans. For the first time, mutagenesis and next generation sequencing can be paired in forward genetic screens to interrogate the whole genome for lifespan-extending mutations in a truly unbiased manner. This innovative approach has the potential to reveal novel modulators of the ageing process. Taken together, this work aims to understand molecular mechanisms that maintain cellular homeostasis to slow the ageing process, and to develop a new technology to identify yet unknown genetic modulators of ageing.";1500000;1500000;ERC-2014-STG;/ERC-STG;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;DE;;;;1;0;0;1;0;0 197301;665940;FutureTDM;CLOSED;H2020-EU.5.f.;GARRI-3-2014;H2020;Reducing Barriers and Increasing Uptake of Text and Data Mining for Research Environments using a Collaborative Knowledge and Open Information Approach;2015-09-01;2017-08-31;;The exponential growth of data in the digital age has led to the development of powerful techniques for effectively harnessing digital information and discovering new knowledge. In this context, Text and Data Mining (TDM) enables researchers from different disciplines to analyse, extract insights and knowledge, and exploit diverse and complex datasets from various digital media. However, the present use of TDM in Europe is significantly lower than in the US and Asia, most probably due to limitations imposed by the European legal framework. In this light, the FutureTDM project identifies and reduces the barriers that inhibit the uptake of TDM for researchers, and innovative businesses. FutureTDM provides critical up-to-date assessments of legal regulations and policies impacting TDM in the EU, and places them in the international research and innovation context. It adopts a bottom-up approach by initiating dialogue between all relevant stakeholders, engaging them via knowledge cafés, workshops and representation on the advisory board to help identify barriers, common solutions and increase awareness of TDM practices and their potential. This combined approach will lead to developing novel policy frameworks and interdisciplinary case-driven practitioner guidelines facilitating the spread of TDM activities. Key to success will be the engagement of actors in the broader community (libraries, publishers, funders, etc.), who will be mobilised through workshops and will be provided with targeted recommendations in the Roadmap for TDM’s uptake. The knowledge distilled from quantitative and qualitative research will be integrated into a Collaborative Knowledge Base and Open Information Hub (www.FutureTDM.eu) using insightful visualisations. This dynamic platform will showcase excellence in TDM research and data-driven innovation and serve as reference for current and future TDM practitioners ensuring broader TDM uptake to boost Europe’s research and innovation capacities.;1492370;1492370;H2020-GARRI-2014-1;/CSA;SYNYO GmbH;AT;"FUNDACJA PROJEKT: POLSKA;UBIQUITY PRESS LIMITED;STICHTING KATHOLIEKE UNIVERSITEIT;OPEN KNOWLEDGE FOUNDATION LBG;ATHINA-EREVNITIKO KENTRO KAINOTOMIAS STIS TECHNOLOGIES TIS PLIROFORIAS, TON EPIKOINONION KAI TIS GNOSIS;THE BRITISH LIBRARY BOARD;STICHTING LIBER;UNIVERSITEIT VAN AMSTERDAM";"PL;UK;NL;EL";;1;0;0;1;0;0 197283;659881;TRECKQUITY;CLOSED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Social equity goals in conservation interventions: a system thinking approach to track progress at global level;2015-10-19;2017-10-18;;The rapid decline of the planet’s biodiversity has prompted governments to adopt an ambitious target to halt the loss of biodiversity and ecosystem services by 2020 through the expansion of protected sites, the Aichi Target 11. Despite this target includes the commitment to reach equitable protected sites that should do no harm local people, we still do not have an adequate way to track progress towards achieving equity in conservation interventions. Global indicators are ineffective in capture the complexity and interactions of multiple factors influencing well-being of local communities. The evidence from case studies at local level show ambiguous conclusions that provide little support for broader scale decision making due to the lack of agreed conceptual understanding and standardized methodologies. The aim of this project is build up an innovative methodological approach to track global achievement of equity in conservation interventions from cases studies. This project employs system thinking methods to conceptualize equity in conservation interventions as a dynamic system. This project will gather the scattered information from multiple datasets and case studies and bring them into this system to simulate their behaviour over time by modelling tools. The project will be hosted by an interdisciplinary group, integrating the methodological expertise on conservation interventions and modelling of the CMEC, with the experience analysing governance regimes and politics issues, economic and livelihoods strategies of IFRO, at the University of Copenhagen. The project will focus on policy relevant analyses, taking advantage of a strong collaboration with the WCMC in UK for communication and implementation of outcomes. The outcomes from this project will comprise the first contribution to tracking our progress on reaching equity in conservation interventions, which is necessary to support critical decision making and actions.;200194,8;200194,8;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;KOBENHAVNS UNIVERSITET;DK;;;;1;0;0;1;0;0 195087;655283;3DWISE;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;3D Full Waveform Inversion on seismic data at the East Pacific Rise;2015-09-01;2017-08-31;;"The mid-ocean ridge system is the longest volcanic mountain chain that wraps around the Globe along which two plates have been separating and oceanic crust has been forming by highly active magmatic processes operating within and at the base of thus formed crust. It is believed that there is a strong link between these magmatic processes known at large spatial scales (1-100 km) and relatively localized (0.001-1 km) tectonic/ volcanic/hydrothermal/biological processes, and their expression onto the seafloor. However, the characteristics of the link are largely unknown. The origin of the most of the unknowns is embedded in poorly defined properties of the upper crust (its structure, P and S wave velocities, porosity, density, anisotropy, etc.), where the link is hosted and its activity is taking place. To map these properties at an unprecedented resolution scale and unveil the existing link, we propose to apply an advanced three-dimensional (3D) full waveform inversion (FWI) technique, which has been recently developed in partnership with industry, to a unique 3D seismic reflection data acquired at the East Pacific Rise. The proposed work will not only result in detailed spatial characterization of the upper crust, but also lay foundation for the 3D FWI as a standard tool for 3D geophysical subsurface exploration of, but not limited to, global tectonics. The study area, the East Pacific Rise at 9?50’N, is a portion of the mid-ocean ridge system characterized by prolific hydrothermal activity, two documented volcanic eruptions and substantial multidisciplinary time-series measurements (unique on the Earth), offering interdisciplinary approach to solve one of the most fundamental problems in Earth sciences. These results will also enable us to tackle some of the long-standing questions on patterns of hydrothermal flow, signature of fine-scale tectono-magmatic segmentation through the upper crust and volume estimates of the erupted lava emplaced on the seafloor.";173076;173076;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;INSTITUT DE PHYSIQUE DU GLOBE DE PARIS;FR;;;;1;0;0;1;0;0 195483;657650;DLCHHB;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2014-GF;H2020;Artificial Tissue Actuators by the 3D Printing of Responsive Hydrogels;2015-07-01;2017-12-31;;"This proposal describes the 3D printing of hydrogel droplet networks to prepare artificial tissue-like materials that demonstrate stimulus-responsive chemo-mechanical actuation. A recent breakthrough by Prof. Bayley’s research group has enabled the 3D printing of self-supporting droplet networks which can be functionalised to allow rapid electrical and molecular communication along a specific path. As a result of this, an opportunity now exists to prepare tissue-like materials that can perform mechanical work in response to external stimuli. By printing biocompatible and responsive polymer hydrogels into droplet networks, artificial muscles will be prepared that display specific and well-defined motion. The resulting technology will be of great importance for a variety of biomaterial applications, with future European Union (EU) industrial growth as well as the public ultimately benefiting from progress in this area. This proposal is inherently multi- and interdisciplinary, involving aspects of synthetic chemistry, polymer chemistry, materials science, chemical biology and biophysics. The different expertise of Prof. Hawker, University of California, Santa Barbara (hydrogels, responsive polymers and biocompatible materials), and Prof. Bayley, University of Oxford (3D printing of artificial tissue, lipid bilayers and membrane proteins), are ideally suited for the successful completion of the proposed research objectives. Due to his prior experience and track record, the experienced researcher, Dr. Lunn, will be able to effectively drive the progression and dissemination of the proposed research. Ultimately, this project will allow one of the United Kingdom's top young researchers to spend time at one of the highest ranked materials research institutes in the world, and transfer the knowledge back to the EU via the University of Oxford. After the fellowship, Dr. Lunn will use the knowledge and skills acquired to obtain an independent academic position within the EU.";226825,2;226825,2;H2020-MSCA-IF-2014;/MSCA-IF-GF;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;UK;;;;1;0;0;1;0;0 198301;675680;BlueBRIDGE;SIGNED;H2020-EU.1.4.1.3.;EINFRA-9-2015;H2020;Building Research environments for fostering Innovation, Decision making, Governance and Education to support Blue growth;2015-09-01;2018-02-28;;"BlueBRIDGE responds to the Juncker Investment Plan opening funding opportunities for e-Infrastructures, innovating current practices in producing & delivering scientific knowledge advice to competent authorities & enlarges the spectrum of growth opportunities in distinctive Blue Growth areas. BlueBRIDGE builds on existing EU and International e-Infrastructures providing capacity building in interdisciplinary research communities of scientists, data managers & educators in academic institutions & industries focusing on 4 major challenges: 1) stock assessment 2) socio-economic performance analysis in aquaculture 3) fisheries & habitat degradation monitoring 4) education & knowledge bridging on protection & management of marine resources. BlueBRIDGE capitalizes on past investments and uses a proven e-Infrastructure connecting 1500\ scientists, integrating \50 repositories, executing \13,000 models & algorithms/month; providing access to over a billion quality records in repositories worldwide, with 99,7% service availability. BlueBRIDGE focuses on user needs, opening services & data to actors & liaising with competent agencies & SME Innovation Clusters. Major results include service-driven research environments addressing concrete challenges, data and a wide range of user defined Blue Growth indicators. BlueBRIDGE leverages a set of common services that together foster the realization of an innovative infrastructure-based approach for collaborative knowledge and data sharing, publishing, citation, traceability & trust concretely contributing to the e-Infrastructure Commons. BlueBRIDGE will be deployed in 30 months by an authoritative & complementary consortium with expertise in multiple scientific domains. It bundles forces from International Government Organizations, research institutes, industry, SMEs, education and computer science domains, establishing a network with a proven track in VREs & e-Infrastructures, marine, environmental & fisheries science & economy.";5295753,75;5295753,75;H2020-EINFRA-2015-1;/RIA;CONSIGLIO NAZIONALE DELLE RICERCHE;IT;"FOOD AND AGRICULTURE ORGANIZATION OF THE UNITED NATIONS FAO;OLOKLIROMENA PLIROFORIAKA SISTIMATA;ETHNIKO KAI KAPODISTRIAKO PANEPISTIMIO ATHINON;FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS;STIFTELSEN GRID ARENDAL;ASSOCIATION POLE MER BRETAGNE;COMMUNICATION & INFORMATION TECHNOLOGIES EXPERTS ANONYMOS ETAIREIA SYMVOULEFTIKON KAI ANAPTYXIAKON YPIRESION;INTERNATIONAL COUNCIL FOR THE EXPLORATION OF THE SEA;COLLECTE LOCALISATION SATELLITES SA;TRUST-IT SERVICES LIMITED;ENGINEERING - INGEGNERIA INFORMATICA SPA;GEIE ERCIM;INSTITUT DE RECHERCHE POUR LE DEVELOPPEMENT";"IT;EL;NO;FR;DK;UK";;1;0;0;1;0;0 195845;659773;SeisMo;CLOSED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;SEismology of the MOon;2016-02-01;2018-01-31;;"As part of the Apollo lunar missions, four seismometers were deployed on the near-side of the Moon between 1969 and 1972, and operated continuously until 1977. There are many difficulties associated with determining lunar structure from these records. As a result, many properties of the moon, such as the thickness, density and porosity of the crust are poorly constrained. This hampers our ability to determine the structure, geochemical composition of the moon, its evolution, and ultimately the evolution of the solar system. This proposal uses modern seismic processing techniques to overcome these limitations. Using ambient noise tomography, it will provide a new, more accurate, model of the lunar crust and mantle. I will apply recent advances in the full waveform modelling of scattering at planetary scale by the host institution to the strongly scattering lunar crust. We will explore entirely new routes for planetary seismology by investigating single-station inverse problems building on recent work in rotational seismology pioneered at the host institution. The project is designed to develop a profile for myself as a planetary seismologist, and to position myself and the host institution to work on the Mars InSight mission in the future. InSight is a NASA Discovery mission, scheduled to land in September 2016, which will deploy a single seismometer on the surface of Mars. We combine the expertise of the researcher in surface wave analysis and tomographic modelling; the facilities and expertise of Ludwig Maximilian University (LMU) in ambient noise studies, full waveform modelling, modelling of seismic scatter and rotational seismology; and an interdisciplinary team of researchers with experience of the techniques and with diverse interests in geochemistry, geodynamics and planetary evolution.";171460,8;171460,8;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN;DE;;;;1;0;0;1;0;0 195051;655134;SOS-Nano;CLOSED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Structure – Oxidative Stress relationships of metal oxide nanoparticles in the aquatic environment;2015-11-01;2017-10-31;;"The SOS-Nano project will address one of the most pressing cutting edge issues of econanotoxicology at present: to find a structural property of nanoparticles (NPs) to predict their potential toxicity in real aquatic environments, the final sink of released NPs. By using an in vivo natural water exposure system, SOS-Nano will test the suitability of two paradigms, recently demonstrated effective in vitro for ranking the hazard of metal oxide NPs: 1) NPs physical-electrochemical properties for predicting oxidative stress potential, and 2) oxidative stress generation for predicting biological impact. The experimental plan of SOS-Nano is totally innovative for design and methodology: the relationships between NPs structure and toxic activity will be studied under the influence of natural water properties, and the toxic potential will be ranked through a multi-tier system combining genomics and functional measurements. The science of SOS-Nano will have high impact: nanotechnology is one of the six EU Key Enabling Technologies selected by the EU Commission to address the industrial-economic competitiveness and the grand societal challenges in Europe by 2020 (US$ 2.5 trillion of world market, 2 million of employers by 2015). The lack of a sound human and environmental risk assessment of NPs is now the major limitation to the safe growth of this economic sector, and the EU research community is tasked with addressing the nanotechnologies development toward sustainability. The SOS-Nano project will represent the perfect opportunity for the applicant to join a cutting edge working environment in which she will realise her potential as a leading nanosafety expert in EU. The host Institution, the University of Exeter, is in the top 10 UK Universities which will provide exciting opportunities for gaining interdisciplinary experience of novel approaches in ecotoxicology and for networking with industry and international partners at the forefront of environmental nanoscience.";183454,8;183454,8;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;THE UNIVERSITY OF EXETER;UK;;;;1;0;0;1;0;0 204568;722963;SOCIETY;CLOSED;H2020-EU.1.3.5.;MSCA-NIGHT-2016;H2020;in Search Of Certainty - Interactive Event To inspire Young people;2016-06-01;2017-11-30;;"SOCIETY (in Search Of Certainty – Interactive Event To inspire Young People) European Researchers' Night events will take place in 5 cities (Bologna, Forl?, Cesena, Ravenna and Rimini). SOCIETY aims to present research as the best tool to investigate solutions, ideas and innovations to sort out the Societal Challenges that human beings face. In order to achieve its objectives, SOCIETY will rely on interactivity and engagement at large: the project will specifically aim to produce a Night co-design approach, in which researchers together with society will conceive the event programme. SOCIETY project will be extended to two editions of ERN, in 2016 and in 2017, with a project duration of 18 months. The line-up of each Night event will be structured as a subway map, with different lines and stops. Each line will represent an interdisciplinary pathway in some specific big topic for which researchers are trying to find some possible solutions and ideas. The two events will maintain the same overall theme, but a relevant evolution in public collaboration, which will support the design of the programme event, will be envisaged. The co-design of ERN events will act as a concrete lab experience for European researchers in structuring a bottom-up public communication event. The public will have a key role in the project, not only as target, and will be engaged to collaborate in the outline of an event tailored for societal interests. Researchers and research will benefit from this approach as a whole in terms of public support and acknowledgement of the importance of research work for society. SOCIETY Night events will be designed in order to attract different kinds of publics . However, secondary school students, who are about to make their choice in terms of career, will be a privileged target, also through the involvement of Eu and MSCA researchers. Specific activities will be addressed to encourage female young students to embark on scientific and research career.";155375;155375;H2020-MSCA-NIGHT-2016;/CSA;ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA;IT;"FORMICABLU SRL;ISTITUTO NAZIONALE DI ASTROFISICA;CONSIGLIO NAZIONALE DELLE RICERCHE;ISTITUTO NAZIONALE DI GEOFISICA E VULCANOLOGIA;CINECA CONSORZIO INTERUNIVERSITARIO;ISTITUTO NAZIONALE DI FISICA NUCLEARE";IT;;1;0;0;1;0;0 195889;660104;SIAM;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Sex-Specific Interactions in Arbuscular Mycorrhizas in an Ecological Community Context;2015-04-13;2017-04-12;;"The importance of below-ground organisms for plant growth, plant community dynamics and ecosystem processes is widely recognised. Among them, arbuscular mycorrhizal symbioses are key elements as they mediate plant resource acquisition. The effects of arbuscular mycorrhizal fungi on plant fitness have been extensively studied in sexually monomorphic plants, but plant populations with separate sexes are relatively common in nature. Usually sexes differ in their resource needs and allocation patterns. Because arbuscular mycorrhizal symbioses mediate resource acquisition and allocation patterns through imposing both costs and benefits to the plants, it is not surprising that sex-specific interactions between arbuscular mycorrhizal fungi and sexually dimorphic plants occur. This is an extremely novel field of research. Most available studies on this topic have been exclusively focused on two trophic levels, neglecting the fact that plants live in complex multi-trophic scenarios, where both mutualistic and antagonistic relationships interact both above- and below-ground. The aim of this research project is to explore and understand plant – arbuscular mycorrhizal fungal interactions in a more realistic multi-trophic context. The essence of the project lies in the interdisciplinary and multidisciplinary approach as it will cover plant and insect ecology, fungal ecology and genetics, and chemical ecology. Implementation of this project has scientific importance for the improvement of our understanding of complex multi-trophic interactions in plants and has potentially enormous economic significance for agriculture as it includes pollination ecology and herbivory. Besides the scientific importance of the proposed project itself, this project will significantly enhance the applicant’s career by acquiring up-to-date techniques and other significant skills and provide expertise on mycorrhizal research for the host institution.";183454,8;183454,8;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;UNIVERSITY OF LINCOLN;UK;;;;1;0;0;1;0;0 195669;658789;BIDAMARK;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;BIg DAta-driven MARKeting for better competitiveness;2015-06-01;2017-05-31;;Big data analysis has become a source of competitive advantage for businesses and even whole economies. Big data is indeed a critical issue for the digital economy, innovation and services that are expected to drive growth and job creation in the EU. Compared to the USA, however, the EU has been slow in the adoption of big data analysis. Fortunately, big data opportunities still exist in many business sectors to improve the competitiveness of European firms. In particular, performance may be improved by making use of big customer data to offer goods and services that better meet customer needs, i.e., “big data-driven marketing (BDM)”. However, adopting BDM has a steep learning curve due to organizations’ lack of understanding regarding the diverse factors required to succeed. The BIDAMARK project aims to assess the impact of different success factors on BDM, and consequently on firms’ ability to achieve superior customer performance. To answer this question, a comparative analysis between France- and US-based firms, and between industry sectors, will be implemented. A quantitative survey methodology will be applied with structural equation modelling (PLS) as the primary analysis method. This project is a perfect springboard for the Principal Investigator (PI) through the opportunity to build durable research networks, and acquire new skills that are complementary with his current expertise. New skills include research skills (theoretical and methodological), technical skills (use of new software tools), project management skills (lead of interdisciplinary project), language skills (French), and training skills (course teaching). Moreover, the publication of conference papers (later developed into high-impact journal articles) and recommendations for decision-makers will contribute to the improvement of the visibility of the PI’s research, and positively influence his academic career. Finally, this project builds a foundation for future collaborations.;173076;173076;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;UNIVERSITE TOULOUSE 1 CAPITOLE;FR;;;;1;0;0;1;0;0 194832;653184;MPerS;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Sustainable Mixed-ion Layered Perovskite Solar Cells;2015-04-01;2017-03-31;;We propose to create and investigate new types of organic-inorganic perovskite materials for low-cost solar cells. The state-of-the-art perovskite based solar cells employ MAPbI3, which has raised concerns over the potential toxicity of Pb. The strategy of the MPerS project is to create, investigate and optimise sustainable perovskite materials for solar cell application. More than one types of metal and organic ions will be introduced in the perovskite structure to realize layered materials which are expected to exhibit both excitonic and free carrier behavior with enhanced stability. Thin films of the new materials will be characterized using several techniques, e.g. Xray diffraction. THz, Time resolved emission spectroscopies, EBIC will be used to understand the generation and dynamics of charge carriers in the materials and across interfaces. Development of solar cells will be carried out with an aim to reach 15% power conversion efficiency employing a non-toxic absorber. This highly interdisciplinary project that spans the field of chemistry, condensed matter physics, electronics and engineering is conceived on basis of the combined expertise of the host and the applicant and state-of-the-art infrastructure at the UOXF. A secondment at Oxford PV will test the commercial viability of the project. This project addresses Horizon 2020’s goals on clean and sustainable energy and the EU’s concern on toxicology of Pb . Completion of the project will open up new areas in low-cost electronic materials with wider impact and improve EU’s competitiveness in materials research. While the applicant will get an opportunity to learn new experimental skills in condensed matter physics and spectroscopy and benefit from industrial exposure. UOXF will benefit from the applicant by using his skills and broader broader collaboration with leading researchers in materials science. A plan is also proposed to carry out public engagement, dissemination and commercial exploitation.;195454,8;195454,8;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;UK;;;;1;0;0;1;0;0 195188;655890;TiFuN;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Tiny Functional Au Nanorods: Novel NIR-Photothermal Nanoprobes for Single-Molecule Tracking at Confined Cellular Environment;2015-04-01;2017-03-31;;Photothermal Imaging (PhI) is an absorption detection technique used for the detection of single gold nanoparticles (NPs), which can be a valuable tool to tackle complex cellular activities. In order to study the dynamics of individual proteins in confined regions such as in neural synapses or in cell adhesion sites, small nanoprobes are needed. Gold NPs (~ 5 nm) can be used, however their surface plasmon resonance (SPR) is centered at 530 nm, a spectral domain where absorption of cellular organelles results in a background signal, which limits the sensitivity of PhI. A brilliant way to find the needle in the haystack is the development of a novel nanoprobe having NIR-absorption, smaller size and high specificity. In “TiFuN”, we will achieve this goal by developing tiny (length/diameter <10 nm/5 nm) gold nanorods (T-rods), an elongated gold NP with tunable SPR in the NIR-window. Different aspect ratio T-rods harvested using Density Gradient Ultrahigh (DGU) centrifugation protocol will be highly promising probes for multicolor labeling and detection of proteins. A dedicated PhI setup based on NIR-laser sources will also be built. Subsequently, the bioconjuagted T-rods and NIR-PhI will be used to study the dynamics of neurotransmitter receptors in synapse and integrin proteins in cell adhesion sites owing to their small core volume, NIR-absorption, exceptional photostability, and non-toxicity. Bioconjugated T-rods will also display the unique property of being easily detected with light and electron microscopy at the single- molecule level, and therefore will be a valuable tool for light/electron correlative microscopy. This highly interdisciplinary project (optics, chemistry and biology) will utilize the fellow’s expertise in nanochemistry in combination with world-leading expertise of Prof. Lounis group in single-molecule detection and Dr. Choquet institute in neuroscience and cell biology.;185076;185076;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FR;;;;1;0;0;1;0;0 199141;689238;PreventIT;SIGNED;H2020-EU.3.1.4.;PHC-21-2015;H2020;Early risk detection and prevention in ageing people by self-administered ICT-supported assessment and a behavioural change intervention delivered by use of smartphones and smartwatches;2016-01-01;2018-12-31;;Lifestyle, disease and biology put older people at risk of functional decline, leading to falls, cognitive impairment, frailty, and negative consequences for quality of life. PreventIT will develop and test an ICT based mHealth System (iPAS) for the consumer market that 1) enables early identification of risk of age-related functional decline, and 2) engenders behavioural change in younger older adults in order to adopt a healthy, active lifestyle. We will use an integrated system of a smartphone/watch as frontend technology and a protected cloud-based solution for handling of personal data as backend technology. We will develop online instruments for risk-screening, complexity metrics, motivation for behavioural change, and a method for personalise exercise by phenotype, based on currently available big data sets. The ICT based intervention we develop is unique, delivered on a smartphone/watch with exercise integrated in daily life and a behaviour change programme. We will evaluate the role of technology and behavioural change theories in risk prevention by performing a multinational feasibility RCT to compare with the same intervention without use of technology and with practice as usual. Usability and feasibility will be in focus, and ageing people will be included in all phases of the project. At the end of the project all assessment and intervention components will be integrated into a personalised self-administered activity system, designed to empower ageing people to control their own health and function. A microsimulation health economics model will be developed to predict effects of our risk prevention intervention on carers and the health care system. PreventIT will be performed by a strong interdisciplinary team with previous impact in the field of ageing and ICT, and commercial partners who are strong on technology development and exploitation are included to increase the chances for iPAS to become a first choice mHealth system for the ageing generation.;4607950;4000000;H2020-PHC-2015-single-stage;/RIA;NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU;NO;"THE UNIVERSITY OF MANCHESTER;STICHTING VU;AZIENDA UNITA' SANITARIA LOCALE TOSCANA CENTRO;ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE;HEALTH LEADS BV;AZIENDA SANITARIA DI FIRENZE;ROBERT BOSCH GESELLSCHAFT FUR MEDIZINISCHE FORSCHUNG MBH;ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA;DOXEE SPA";"UK;NL;IT;CH;DE";;1;0;0;1;0;0 196025;660976;BrainiAnts;TERMINATED;H2020-EU.1.3.2.;MSCA-IF-2014-GF;H2020;Evolution of the social brain: How social complexity affects individual cognition in ants;2015-08-01;2018-12-31;;"This project aims to answer a significant open question in evolutionary neurobiology: how social complexity shapes the brain structure, its associated metabolic costs, and the behavioural capability of individual members of a society. The Social Brain Hypothesis proposes that the complexity of living in group influences encephalization in vertebrates, but this theory has not been critically tested in invertebrate species. Social insects such as ants have miniaturized brains that nevertheless support highly coordinated collective behaviour and striking individual cognitive abilities. This collective behaviour produces an “externalized” distributed processing of information that may reduce energetic expenses in individual brains. We propose to address this question through the study of brain metabolic costs of ant foragers under different conditions of sociality. We will examine the effect of distributed information processing (such as the use of pheromones trails to coordinate group activity) on individual cognitive abilities (such as learning) and the energetic costs of specialized brain compartments that underlie behaviour. Our interdisciplinary methodology will combine techniques applied to the study of collective animal behaviour (individual tracking in collective choice and foraging experiments) and neurobiology (immunohistochemistry and neuroanatomical scaling, cytochrome oxidase staining and learning assays) in sister clades of ants that show strong differences in social complexity and thus the relative roles of individual workers and cooperative groups. This novel and integrated approach will allow us to analyze the evolutionary relationship between social complexity and brain evolution.";246668,4;246668,4;H2020-MSCA-IF-2014;/MSCA-IF-GF;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FR;;;;1;0;0;1;0;0 207962;761940;Tinnitus Platform;SIGNED;"H2020-EU.3.1.4.;H2020-EU.2.1.1.;H2020-EU.2.3.1.;H2020-EU.3.1.6.";SMEInst-06-2016-2017;H2020;Commercialization of novel Diagnostic Platform with Synaptic adaptation Arc treatment method for tinnitus patients.;2017-02-01;2017-05-31;;"Meeting demand for the first medical device for diagnosis and therapy of tinnitus is set to be a crucial challenge for future audiology and neurology. For that reason Kinetic Center of Advanced Audiology (www.kinetic-cna.pl/) aims to commercialize technologies for the Tinnitus examination and treatment. To do so, co-founders rely on their extensive experience and the interdisciplinary team of: audiologists, laryngologists, medical technicians, neurobiologists, neuroscientists, musical trainers, hearing care professionals, clinicians and nutritionists. Our main objective today is to bring to the global market a novel “Tinnitus Diagnostic Platform” which is a IT platform of multiple test, that can give more information and indicate with more precision the nature of the tinnitus and “Synaptic adaptation Arc therapy” which is dedicated for tinnitus patients after sudden hearing loss. We have conducted preliminary research studies on a small group of around 200 patients and the promising results encouraged us to demonstrate clinical effectiveness of our solution on n a bigger number of subjects. The key market application of Tinnitus Diagnostic Platform is to differentiate the pathology of hearing and finally to select appropriate treatment. Synaptic adaptation Arc therapy is based on continuous acoustic stimulation which enforces activity of hear cells and nervous system and gives opportunity to release Arc/Arg 3.1 protein that rebuild synapses. The project addresses the problem of lack of medical device for tinnitus diagnosis and very poor research on the course of the condition. Finally, to fully exploit and to commercialize this new and EU-based technology, we want to open new Advanced Audiology Clinics around Europe to propose complex methods on hearing pathologies. The Future growth will be driven through sales of Tinnitus Diagnostic Platform to other Audiology Clinics (B2B) and sales of Synaptic adaptation Arc therapy treatment set to patients (B2C).";71429;50000;H2020-SMEINST-1-2016-2017;/SME-1;KINETIC CENTRUM NOWOCZESNEJ AUDIOLOGII SPOLKA Z OGRANICZONA ODPOWIEDZIALNOSCIA;PL;;;;1;0;0;1;0;0 197987;674868;APRIL;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2015-EID;H2020;Applications of Personal Robotics for Interaction and Learning;2016-01-01;2019-12-31;;The aim of personal robotics is to design companion robots that can live and interact with people in a very intuitive way. This requires designing robots that are capable of adapting to the human users, via learning during interaction. This proposal aims at the timely establishment of the first European Industrial Doctorate in “Applications of Personal Robotics for Interaction and Learning” (APRIL) to train future researchers and engineers for the emerging field of personal robotics. APRIL strategically adopts a key entrepreneurial ethos which will equip PhD students with radical cross-sector and interdisciplinary skills and mind-set, by combing research on developmental and social cognitive systems with hands-on experiments on the application of human-robot interaction and assistive systems. APRIL is the result of the strategic synergies of Plymouth University Centre for Robotics and Neural Systems with its international leadership and reputation as UK and European hub in cognitive developmental robotics and human-robot interaction, and with Aldebaran Robotics A-Lab R&D Division which has the world leading market position in the personal robotics industry with the robots NAO and Pepper. This is complemented by six international partners from industry (SONY Corporation, MetraLabs GmbH), academia (Osaka, Humboldt Berlin) and robot users (San Raffaele Hospital Milan and SSSA DomoCasa Pisa). The doctoral training strategy of the EID will implement the latest innovative PhD training approaches of situative and social constructivist learning theories with a unique Coaching Programme for a tailored Individual Skills Development Plan, peer-support and student-centred cohort activities, as well as a strong leadership skills programme for continuous professional development. The two beneficiaries will contribute with a pool of over 12 academic and industry supervisors and will fund 5 additional PhD bursaries to match the EID cohort of the 5 Marie Sk³odowska-Curie funded ESR;1345614,84;1345614,84;H2020-MSCA-ITN-2015;/MSCA-ITN-EID;UNIVERSITY OF PLYMOUTH;UK;SOFTBANK ROBOTICS EUROPE;FR;;1;0;0;1;0;0 196105;661482;GEOCA;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Geometry and Computational Anatomy;2015-03-01;2017-02-28;;"The past decades have brought fascinating technological improvements of medical imaging techniques. This rapid development is accompanied by a growing need for computer based algorithms to align and extract markers from medical images. The days of heuristically engineered computer algorithms are, however, over; competitive, state-of-the-art medical imaging software must be based on rigorous mathematics to ensure accuracy, efficiency, and stability. Our research project lies at the forefront of computational anatomy (CA), a truly interdisciplinary field within medical imaging, combining differential equations theory, numerical analysis, computer vision, statistical methods, and differential geometry. CA is an emerging field that harbours a wealth of challenging problems. In particular, to develop image registration algorithms capable of handling heavily nonlinear deformations. In this project we construct image registration algorithms beyond state-of-the-art, adept of tasks where today's methods are inadequate. This is achieved by combining the knowledge of Professor Stig Larsson (scientist in charge) with the knowledge of Dr Klas Modin (experienced researcher). Larsson is a world-leading expert on numerical methods for partial differential equations. He has a large network of international collaborators as well as close connections to the medical imaging industry in Sweden. Modin has extensive expertise on geometric integration (GI), infinite-dimensional geometry, and CA, acquired via two post-doctoral positions at top research groups in two third countries. He thus brings state-of-the-art knowledge to the European research area. In particular, Modin's mastery of large deformation diffeomorphic metric matching (LDDMM) and Euler--Arnold equations is essential; it provides the link between image registration and PDEs. This link is the basis of the new, exciting methodology in the project: to apply state-of-the-art numerical PDE techniques to image registration.";185857,2;185857,2;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;CHALMERS TEKNISKA HOEGSKOLA AB;SE;;;;1;0;0;1;0;0 195115;655478;NeoGenHeritage;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Neotithic transition in the Iberian Peninsula: reviewing an old question from new technological and computational genome wide approaches;2015-09-01;2017-08-31;;"The research goal of this proposal revolves around a widely debated topic in archaeology, anthropology and population genetics: the dynamics of the spread of farming into Europe, or Neolithic transition. For a long time, this key event that was to define modern Europeans has fuelled a dichotomic research debate. In short, did the Neolithic spread into Europe as the result of cultural or demographic diffusion? While many approaches can be attempted, in the last few years, ancient DNA (aDNA) studies have strongly contributed to shedding light on this topic, through the recovery and analysis of an increasing number of mitochondrial and nuclear genomes from prehistorical human samples. Far from closing the debate, these palaeogenomes are revealing a more complicated scenario, where the times, paths and genetic legacy of the Neolithic diffusion seem to have been different in different geographic areas. Furthermore, as the genomic data increase, the aDNA field is soon facing the challenge of evolving from a research area largely based on technical development for the recovery of short DNA fragments, to the analysis of larger datasets (ultimately, whole genome data) in the context of human population genetics. I therefore propose an interdisciplinary project aimed to increase our knowledge on the Neolithic transition by generating, for the first time, genome data from ancient human remains from the Iberian Peninsula at the times of the Neolithic transition. Having been the last region of Europe reached by the Neolithic diffusion, the IP is a crucial area for understanding the relative role of migration and cultural changes. By combining modern technologies for the recovery of ancient genomes, with state-of-the-art statistical data analyses in the context of human population genetics, this project will contribute to the development of practical and theoretical approaches to make the most of aDNA as a powerful research tool in the fields of archaeology and antropology.";168277,2;168277,2;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;UNIVERSITA DEGLI STUDI DI FERRARA;IT;;;;1;0;0;1;0;0 195431;657314;MBLIs;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;New Approaches to Metallo-?-Lactamase Inhibitors;2015-07-01;2017-06-30;;The increasing problem of antibiotic resistance is a major global public health concern. In the EU 25,000 patients die each year due to infections caused by multi-resistant bacterial pathogens, and the EU spends at least 1.5 billion euro per year on healthcare costs. The ?-lactam antibiotics are the most important antibiotics representing >60% of small molecules in clinical use. BLAs contain a ?-lactam ring which is critical for penicillin-binding protein inhibition. However, BLA efficacy is declining due to resistance mechanisms including the widespread occurrence of ?-lactamases, which catalyse ?-lactam hydrolysis. Metallo-?-lactamases, long-considered as of little clinical relevance, now present a serious global threat to almost all BLAs, rendering the development of approaches to MBL inhibitors important. Unlike the serine ?-lactamases, the MBLs are structurally and mechanistically unrelated to PBPs, and are not inhibited by current mechanism-based SBL inhibitors. Due to variations in MBL structures, a major challenge in MBL inhibition is the development of compounds with the breadth of selectivity necessary for clinical utility. Society is now in an alarming situation and there is a clear need for the development of an MBLI:?-lactam-based combination therapies. The aim of my proposed work is to pioneer, enable and inspire the generation of broad-spectrum MBLIs active against a panel of clinically representative MBLs, but inactive against human enzymes with related active sites. To obtain the desired objective, novel approaches are proposed and include the use of phosphonates and phosphinic acids for: (a) MBL-directed DCC coupled to analysis by non-denaturing ESI-MS and 31P-NMR, (b) 31P-NMR reporter screening method, (c) pre-equilibrated DCLs for MBL-directed DCC, and (d) the synthesis of modified inhibitors. The study will be interdisciplinary and encompass organic synthesis, biological MS/NMR, structural biology, and medicinal chemistry.;183454,8;183454,8;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;UK;;;;1;0;0;1;0;0 195174;655815;MultiFUNGtionality;CLOSED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Fungal diversity, ecosystem services and forest management: unravelling the role and dynamics of fungal communities in multifunctional Mediterranean forests.;2016-01-01;2017-12-31;;Forest fungi are a major biodiversity component of Mediterranean forests, and contribute to providing crucial ecosystem services. Thus, changes in fungal communities driven by environmental factors and human actions on ecosystems may have, ultimately, an impact on human well-being. Understanding and predicting such changes and their subsequent impact on the provision of ecosystem services is crucial to enable scientifically sound decision-making in land–use planning. However, our knowledge on such complex ecological systems is limited due to the high diversity of forest fungi and their cryptic nature. This action aims at addressing such complexity by contributing to unravelling how fungal diversity is affected by several drivers and, in turn, how it affects the provision of multiple ecosystem services to be further integrated into multifunctional forest management. This will be possible thanks to multi-scale, high-quality data on above- and belowground diversity and its potential drivers. Such data will be analyzed using advanced hybrid modelling techniques, and the resulting models will be combined in simulation-optimization routines to enable science-based decision making in forestry sensitive to fungal diversity. This will be the leading thread of an action that aims at having high impact on the research career of Dr. Sergio de Miguel for him to attain a position of maturity as an independent and interdisciplinary researcher.;170121,6;170121,6;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;UNIVERSIDAD DE LLEIDA;ES;;;;1;0;0;1;0;0 194874;653587;LAW-TRAIN;SIGNED;H2020-EU.3.7.;FCT-07-2014;H2020;Mixed-reality environment for training teams in joint investigative interrogation-Intelligent interrogation training simulator;2015-05-01;2018-04-30;;"Interrogations of suspects in international crime are very difficult and require sophisticated skills, familiarity with different -cultures, laws and methods, and cross-border teamwork. Training law enforcement agents on how to conduct such interrogations is the key to fighting these crimes. LAW-TRAIN applies an interdisciplinary approach for international criminal interrogations. It will unify the methodology for such interrogations and will develop a distributed mixed-reality gaming platform that will provide training opportunities to teams of international interrogators anytime and anywhere. The platform will include a virtual human suspect that will be interrogated and generate dynamic verbal and body responses. The system will provide tools to generate new characters and new scenarios easily. An intervention agent will follow the training and comment online on the team members’ performance. LAW-TRAIN builds on advanced technologies of virtual and augmented reality to allow law enforcement personnel (and translators, lawyers and judges) from different countries located in different sites to conduct a collaborative investigative interrogation of one or more suspects. All the investigators will see each other and work as a team. Each of the trainees will have access to his/her country's the information system and will be able to share this information with the other trainees as required in real criminal investigations. The investigational database will be directed at international organized crime focusing on international drug trafficking. However, the LAW-TRAIN engine is designed as a generic engine that will enable development of scenarios for other types of illegal activities as well as other cross-border teamwork training. LAW-TRAIN will be evaluated in an extensive field study with law-enforcement agents from four countries. This will be the first step in the deployment of LAW-TRAIN to fight international organized crime.";5095687,5;5095687;H2020-FCT-2014;/RIA;BAR ILAN UNIVERSITY;IL;"USECON THE USABILITY CONSULTANTS GMBH;OPTIMIZACION ORIENTADA A LA SOSTENIBILIDAD SL;Inspectoratul General al Politiei Romane;COMPEDIA SOFTWARE & HARDWARE DEVELOPMENT LTD;MINISTRY OF PUBLIC SECURITY;Ministério da Justiça;MINISTERIO DEL INTERIOR;DE FEDERALE OVERHEIDSDIENST JUSTITIE - LE SERVICE PUBLIC FEDERAL JUSTICE;INESC ID - INSTITUTO DE ENGENHARIADE SISTEMAS E COMPUTADORES, INVESTIGACAO E DESENVOLVIMENTO EM LISBOA;KATHOLIEKE UNIVERSITEIT LEUVEN";"AT;ES;RO;IL;PT;BE";;1;0;0;1;0;0 195980;660648;FOMBIST;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Fibre-Optic Multi-parametric BIochemical Sensing Technology;2015-10-12;2017-10-11;;"This project aims at developing advanced optical fibre sensing technologies for multi-parametric bio/chemical measurement, urgently demanded from industry and scientific research for quality control and process study. The Fellow, Dr Jiang will be trained on a series of skills related to novel photonic devices and advanced sensing techniques at main host Aston Institute of Photonic Technologies (AIPT) and several other EU hosts. Capitalising upon his original expertise in the study of optical fibre sensing, bio/chemical measurement and liquid diffusion process, the fellowship will make him a unique asset to the EU for tackling multi-parametric bio/chemical sensing by developing new optical fibre sensing technologies capable of measuring several parameters simultaneously. Dr Jiang has proven track record in bio/chemical sensing with interdisciplinary background and his achievement has been outstanding though very young as demonstrated in his CV. The skills and technologies he will grasp will allow him to diversify his capability significantly; including fibre grating design and fabrication (at AIPT), UV and femtosecond laser micro-fabrication, fibre laser, optical fibre interferometry, nano-film coating techniques and modelling techniques for photonic devices, and highly sensitive sensing technologies. In addition, the fellowship will allow him to transfer the knowledge gained through the research to the benefit of his hosts and regional industrial liaisons together with his existing knowledge on bio/chemical detection. Starting from a particular optical fibre device, tilted fibre grating, through modelling, fabrication and optimisation on special fibres the project will explore the rich spectral characteristics of the device to decode a variety of factors for the multi-parametric sensing. Fostered by the fellowship, a leading expert in photonic sensing technologies is expected and will contribute greatly to EU industries and academic communities.";183454,8;183454,8;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;ASTON UNIVERSITY;UK;;;;1;0;0;1;0;0 195979;660646;PRIME;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Process Invigoration through Model Embellishment;2015-09-01;2017-08-31;;"The objective of this research project is to enhance business process (BP) model comprehension in European organisations through dynamic process invigoration. Analysis and improvement of BPs are key to organisations’ cost efficiency and competitiveness. A growing number of organisations in Europe implement BP management solutions to analyse and automate their processes. BP models are invaluable to define, control, improve and communicate BPs. BP models abstract a dynamic phenomenon in the form of a static representation, thus they are often difficult to comprehend. In this research, I aim at redefining the BP model comprehension problem and developing innovative solutions through a synergetic usage of process modeling and multimedia disciplines. In this way, models will be dynamically invigorated and presented to business professionals in a comprehensible manner. To fulfil the overall objective, related literature will be reviewed; BP model invigoration techniques will be designed for eight different embellishment components; the techniques will be evaluated through industrial experiments and field studies; an open source BP model invigoration tool will be developed; and results will be disseminated in European academy and industry. Eventually, organisations from various domains in Europe can utilize their BP models in a better way by using the freely available PRIME tool to invigorate their processes. This will create an opportunity to increase organisational efficiency throughout Europe. This project will contribute to my career development in many ways. I will obtain regular training on scientific and transferable skills through interdisciplinary trainings with my supervisor and other scholars, courses in research schools, and the preparation of publications. Collaboration and networking will be enhanced through joint studies with scholars and industry, enabled by the supervisor’s previous collaborations as well as my experiences.";165598,8;165598,8;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;STICHTING VU;NL;;;;1;0;0;1;0;0 195471;657569;TRAIT;CLOSED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Exploring the biogeography of thermal acclimation in heterotrophic microbes;2015-07-01;2017-06-30;;Understanding the biological mechanisms governing carbon (C) exchanges between terrestrial and atmospheric C pools, and how these exchanges will respond, and feed back, to climate warming, are among the most urgent challenges for climate and ecosystem scientists. Heterotrophic microbes are dominant biochemical engineers in terrestrial ecosystems, governing the flux of C between terrestrial and atmospheric pools. Despite concerns that rising atmospheric temperatures will stimulate the respiratory release of C by heterotrophic microbes, recent work highlights the potential for thermal acclimation to partially ameliorate this positive feedback. The magnitude and efficiency of this physiological response is, however, highly variable, suggesting that the strength of climate-ecosystem C feedbacks will vary across landscapes. The proposed study uses a combination of trait-based and community-scale approaches to explore the relative importance of microbial community composition and climate conditions in governing patterns of acclimation potential across landscapes. Incorporating this microbial physiological information into Earth System Models (ESMs) is essential if we are to predict global patterns in biogeochemical cycling under current, and future climate scenarios. The proposed work incorporates aspects of microbial physiological biology, community ecology and ecosystem ecology to address a critical uncertainty in current climate models. This interdisciplinary project will allow me the opportunity to exchange knowledge with experts in the fields of microbial community ecology and terrestrial ecosystem ecology at NIOO-KNAW. I will also foster an international collaborative network, which will benefit my host organisation and myself. The proposed fellowship will allow me re-enter the European academic system and develop the skills required to initiate my own effective research group following the project.;165598,8;165598,8;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW;NL;;;;1;0;0;1;0;0 195357;656917;River-HMV;CLOSED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;River hydraulics, morphology, and vegetation: A case for improved knowledge and numerical model capabilities;2015-10-01;2017-09-30;;The interdisciplinary knowledge and ability for river managers to effectively predict flood risks, restore rivers, and assess future alterations are currently restricted to the limited understanding of how river hydraulics, morphology, and vegetation alter a river’s planform, effect sediment mobility, and control the surrounding habitats. To improve this knowledge and capabilities, this research seeks to i) use physical model flume experiments to quantify the hydraulic, morphologic, and vegetation interactions of a braided channel as well as investigate the use of manipulated channel avulsion as an innovative method to increase a river’s floodplain conveyance, ii) to quantify the accuracy of a cutting-edge numerical model’s simulations, and iii) to improve the numerical model’s functionality. Through increased knowledge, improved model capabilities, and potentially identifying a new technique to increase a degraded river’s floodplain dynamics, this research can improve the efficacy of river managers around the world. In particular, Europe could utilize the contributions of this research to help meet the ecological-morphological aspects of the Water Framework Directives and Flood Directives and to restore many of the heavily altered rivers of the European Alps.;180277,2;180277,2;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;UNIVERSITA DEGLI STUDI DI TRENTO;IT;;;;1;0;0;1;0;0 195325;656782;PETITE GUERRE;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Experiences and Memories of French and Algerian Veterans. Remembering the 'petite guerre' in the Aur?s-Nememcha;2015-09-01;2017-08-31;;The present study aims to investigate the Algerian War of Independence (1954–62) from a new perspective. It proposes to frame a transnational history of the war, going beyond both the (opposing) French and Algerian (national) narratives, to resituate the war in its Mediterranean, European, and eventually its global contexts. This general research objective, however, will be achieved by using a microhistorical approach: instead of looking at the conflict as a generic “whole” and examining its reverberations in an elusive “collective memory”, the project focuses on a specific region, the Aur?s-Nememcha in the Algerian south-east. At the core of this project are the specific experiences and memories of French and Algerian veterans who fought each other for eight years, in this mountainous, Berberophone area. Who were they? What kind of war were they fighting, and why? And fifty years after the ceasefire, how do the citizens of each country cope with their combat memories? The project will mobilise a wide range of sources, mostly but not exclusively French and Algerian. Aiming to analyse both past events and their present memories, this study will rely on both qualitative and quantitative analytical methods, in a truly interdisciplinary framework. Indeed, this “global microhistory” approach—beyond being an original contribution to historical research—aims to offer new knowledge of and insights into the Franco-Algerian War, in order to help the two countries to go beyond the narrow national narratives that continue to fuel an unexhausted “memory war” that is ongoing both between and within Algeria and France. If the efforts of the EU and the Union for the Mediterranean (2008) may help to set a new tone in the near future, today it is less at the state level that it is possible to act than at the level of the people, by focusing on their particular and familial stories.;183454,8;183454,8;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;UK;;;;1;0;0;1;0;0 195206;656093;SynOptic;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Synthetic Gauge Fields in Quantum Optics;2015-10-01;2017-09-30;;"Synthetic gauge fields have many important physical consequences in quantum optical systems. This fast-growing topic of research is opening up new possibilities for the lossless optical transmission of information, for improved optical components, such as optical isolators, and even for fault-free topological quantum computing. We explore how to push cutting-edge experiments towards these goals by theoretically studying the interplay of synthetic gauge fields with optical nonlinearity, pumping and loss in photonic devices. The systems we shall investigate range from artificial graphene and other condensed matter models simulated with microcavities; to lattices of classical pendula and waveguides; to strongly correlated fractional quantum Hall-like states of light and their exotic excitations. Our work will have an immediate impact through international experimental collaborations and an interdisciplinary approach building on our combined range of expertise. We will exploit concepts and techniques from diverse research areas including quantum fluids, topological phases of matter, solid-state systems and non-equilibrium physics. Our project couples the investigation of novel phenomena arising from gauge fields in many-body systems with the hunt for new and improved technological applications in photonics.";168277,2;168277,2;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;CONSIGLIO NAZIONALE DELLE RICERCHE;IT;;;;1;0;0;1;0;0 216834;817240;POC;SIGNED;"H2020-EU.3.;H2020-EU.2.3.;H2020-EU.2.1.";EIC-SMEInst-2018-2020;H2020;PieceOfCake: an AI-driven chatbot to manage complex business data;2018-06-01;2018-11-30;;"The complexity of business data (accounting, marketing, etc.) requires technical skills to handle and process it. However, the roles in a company that need this information to operate are usually different from the ones with those technical skills, also known as business analysts. Third-party solutions or in-house IT departments provide dashboards and reports to fill the gap. Nevertheless, this methodology is (1) expensive in terms of IT time devoted to implementation and maintenance, (2) rigid and difficult to adapt to the particular work-flow of each company, (3) slow and tedious to use. These issues can weigh down a company and translate into lost business opportunities. We propose PieceOfCake, a trained Artificial Intelligence (AI) system that allows the use of Natural Language (NL) to access complex data. Questions like “How many users visited our web during last week for the first time?” will be automatically answered in the form of NL and graphs. Our product will change the way data-driven companies operate. Mid-level managers and interdisciplinary roles (e.g. marketing) are examples of positions that will highly benefit from it. PieceOfCake will outperform traditional dashboards in terms of ease of use, agility, and speed. It will disrupt strategic decision-making and drastically reduce IT costs. It will also allow small enterprises and self-employees to keep pace with the AI wave. The feasibility study will identify which vertical (marketing, analytics, etc.) offers a higher market opportunity, what monetisation strategies work better (SaaS, white-labeling, tailored customers, etc.), and what market segment better accept our strategy. Given the expected impact AI will have in global economy, we believe our project is crucial to the competitiveness of Europe against Asia and United States.";71429;50000;H2020-SMEInst-2018-2020-1;/SME-1;TYRIS SOFTWARE SL;ES;;;;1;0;0;1;0;0 206185;732344;Neurofibres;SIGNED;H2020-EU.1.2.2.;FETPROACT-01-2016;H2020;Biofunctionalised Electroconducting Microfibres for the Treatment of Spinal Cord Injury;2017-01-01;2020-12-31;;"Bio-electronic microsystems hold promise for repairing the damaged central nervous system (CNS). However, this potential has not been developed because their implantation inflicts additional neural injury, and ensuing inflammation and fibrosis compromise device functionality. In Neurofibres we want to achieve a breakthrough in “Neuroregenerative Bio-electronics”, developing dual-function devices that will serve as electroactive scaffolds for CNS regeneration and neural circuit activation. We engineered electroconducting microfibres (MFs) that add negligible tissue insult while promoting guided cell migration and axonal regeneration in rodents with spinal cord injury (SCI). The MFs also meet the challenge of probe miniaturisation and biofunctionalisation for ultrasensitive recording and stimulation of neural activity. An interdisciplinary consortium composed of neuroscientists, medical specialists, researchers in biomaterials, protein engineering, physics, and electrical and mechanical engineering, together with a company specialised in fabrication of microcables and microconnectors, will join efforts to design, develop, and test the MFs and complementary technology (microfibre functionalisation, assembling, and electronic interconnection), in order to produce a biologically safe and effective bio-electronic system for the treatment of SCI. This goal will be achieved through five specific objectives: 1) To improve the electrical conductivity, strength, and chemical stability of the microfibres. 2) To develop electro-responsive engineered affibodies for microfibre functionalisation. 3) To develop the technology for MF interconnection and assembling into implantable systems. 4) To perform comprehensive investigation of the immunological, glial, neuronal, and connective tissue responses to the implanted MFs and applied electrostimulation in rodent and swine SCI models. 5) To investigate the motor and sensory effects of microfibre implantation and electrostimulation.";5888491,25;5094120;FETPROACT-2016;/RIA;SERVICIO DE SALUD DE CASTILLA LA MANCHA;ES;"THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;KUNGLIGA TEKNISKA HOEGSKOLAN;AXON CABLE;UNIVERSITA DEGLI STUDI DI TRENTO;UNIVERSITE D'AIX MARSEILLE;UNIVERSITAT DES SAARLANDES";"UK;SE;FR;IT;DE";;1;0;0;1;0;0 199096;687961;RespiceSME;SIGNED;H2020-EU.2.1.1.;ICT-27-2015;H2020;Regional, National and European Support for Photonics Innovation Clusters enhancing SMEs Innovative Potential;2016-01-01;2017-12-31;;"RespiceSME will reinforce the innovative capacity of Europe’s photonics SMEs, clusters and national platforms by stimulating increased collaborations in and beyond photonics. RespiceSME proposes new approaches for stronger innovative effectiveness using a 3-dimensional approach, led by an experienced, representative, interdisciplinary team. In the 1st dimension, the project will develop a measure of the innovative potential for Photonics SMEs; the index will be integrated with a methodology for auditing innovative SMEs. Coaching on these tools will lead to their diverse application; enhancing the innovative capacity of 30\ photonics SMEs is targeted in the project. In the 2nd dimension, RespiceSME will develop new approaches for analysing value chains in close collaboration with clusters and national platforms. Empowering photonics SMEs and cluster managers to undertake early stage analyses of value chains, in the 3 separate domains of commercial intensity, technology readiness and innovative potential, will lead to more effective penetration by European photonics SMEs in global non-photonics sectors. Approaches will be demonstrated by new business collaborations in photonics, and using photonics, in manufacturing, energy and transport sectors. Harnessing the full innovative capacity of the European photonics infrastructure is the objective of the 3rd RespiceSME dimension. Best practices for enabling photonics SMEs access European and regional infrastructures, harness educational and training programmes aligned with their specific needs, determine next generation regional innovative smart specialisation strategies, and be better resourced by efficient public and private financial supports, can be transformative. RespiceSME will disseminate results using face to face and multimedia tools. 6 events, spanning cluster/national platform, inter-sectoral meetings, and B2B brokerage events and multimedia tools will lead to an intensification of research collaborations.";1109047,5;1109047,5;H2020-ICT-2015;/CSA;STEINBEIS 2I GMBH;DE;"STEINBEIS INNOVATION GGMBH;NATIONAL UNIVERSITY OF IRELAND GALWAY;ASSOCIATION OPTICSVALLEY - AU SERVICE DE L OPTIQUE DE L ELECTRONIQUE ET DE L INGENIERIE LOGICIELLE EN ILE-DE-FRANCE;PHOTONICS AUSTRIA - PLATTFORM ZUR FORDERUNG DER OSTERREICHISCHEN INTERESSEN IM BEREICH PHOTONIKEICH PHOTONIK;FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS;OPTECNET DEUTSCHLAND EV;KNOWLEDGE TRANSFER NETWORK LIMITED;SOUTHERN EUROPEAN CLUSTER IN PHOTONICS & OPTICS ASSOCIACION;EKONOMISKA FORENINGEN PHOTONICSWEDEN;VIESOJI ISTAIGA FIZIKOS INSTITUTO MOKSLO IR TECHNOLOGIJU PARKAS";"DE;IE;FR;AT;EL;UK;ES;SE;LT";;1;0;0;1;0;0 194991;654733;FOC4SIP;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Functionalised Organic Complexes for rapid Sensing of Industrial Polluters;2015-07-07;2017-07-06;;"The ultimate target of the project is to create and transfer knowledge on the development of novel functionalised macromolecular complexes for rapid sensing of hazardous industrial polluters. Recent developments of macromolecular complexes and opto-electronic techniques of their study have enabled advances in the formation of molecular probes able to recognize molecules and metal ions. These advances are currently being considered for application in a new generation of sensor technology, and opto-electronic methods have been proved as sensitive and rapid tools for such detection. However the selectivity and sensitivity of such methods requires further improvement. Here, we propose new detection systems combining use of functionalised macromolecules and development of sensor devices by novel micro-fabrication tools as well as training and career development of prospective researcher up to mature Senior Scientist level. The overall objective of this research is to select and characterise sensor/probe macromolecules (polymethine dyes, functionalised carbon nanomaterials, melanins), then to optimise mechanisms of detection due to interaction of macromolecules with industrial polluters, and finally to develop sensing devices. Performance and usability of the novel sensors will be evaluated in collaboration with industrial partner. This is an ambitious research initiative having strong interdisciplinary approach that combines physics, chemistry, materials science, engineering, and biology. Its success is upheld by combination of complementary expertise of the Fellow, Host and Partners in preparation and characterisation of functionalised macromolecules as well as development of sensing devices. The project will provide benefits in monitoring and detection of hazardous compounds, and optimisation of cleaning routine after industrial pollution. Therefore, positive impact on safety of ambient environment and public health care sector is anticipated.";195454,8;195454,8;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;ASTON UNIVERSITY;UK;;;;1;0;0;1;0;0 195286;656540;EARMEDCASTILE;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;The formation of the state in Early Medieval Castile: craft production and social complexity;2015-07-08;2017-07-07;;"The main goal of the project is to analyse the emergency and the collapse of states in the Early Middle Ages through the study of production and distribution systems, which are consider a marker of social and political complexity. The project is based on two main axes: first at all, an interdisciplinary approach to the analysis of pottery would have the capability of revealing the political background of economic exchange. And even if this approach has been successfully applied to the study of process such as the end of the Roman Empire, at the same time our knowledge about the formation of state in South of Europe is very limited. Secondly, the North of Iberia represents an excellent case study for investigating the transformation of political structure in Early Medieval Europe, taking into account that in this scenario five different states rose and collapsed within only five centuries. Production, distribution and consumption systems would be analysed, in order to highlights evidence for social and political complexity related with the emergence of states. In practical terms, early medieval pottery from 14 sites located in the Old Castile would be studied by Dr. Francesca Grassi, PhD on Medieval Archaeology. The main steps of the project would be (a) the identification of the main workshops located in the upper Ebro valley in early medieval times; (b) the analyses of consumption patterns, by combining pottery studies with bioarchaeological and palaeodiet evidence; (c) the definition of political trends at a local scale and the change of scale that determined the structuration of central powers taking into consideration the distribution systems. The results of the Spanish case studies will be discussed with reference to previous studies carried out in Italy by the candidate, with the aim of inserting the project in a European dimension; this would be achieved by enhancing the existing dialogue between two research groups, GIPyPAC (UPV/EHU) and University of Siena.";170121,6;170121,6;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA;ES;;;;1;0;0;1;0;0 193604;638857;CHROMTISOL;SIGNED;H2020-EU.1.1.;ERC-StG-2014;H2020;Towards New Generation of Solid-State Photovoltaic Cell: Harvesting Nanotubular Titania and Hybrid Chromophores;2015-03-01;2020-02-29;;"In photovoltaics (PVs), a significant scientific and technological attention has been given to technologies that have the potential to boost the solar-to-electricity conversion efficiency and to power recently unpowerable devices and objects. The research of various solar cell concepts for diversified applications (building integrated PVs, powering mobile devices) has recently resulted in many innovations. However, designs and concepts of solar cells fulfilling stringent criteria of efficiency, stability, low prize, flexibility, transparency, tunable cell size, esthetics, are still lacking. Herein, the research focus is given to a new physical concept of a solar cell that explores extremely promising materials, yet unseen and unexplored in a joint device, whose combination may solve traditional solar cells drawbacks (carrier recombination, narrow light absorption). It features a high surface area interface (higher than any other known PVs concept) based on ordered anodic TiO2 nanotube arrays, homogenously infilled with nanolayers of high absorption coefficient crystalline chalcogenide or organic chromophores using different techniques, yet unexplored for this purpose. After addition of supporting constituents, a solid-state solar cell with an extremely large incident area for the solar light absorption and optimized electron pathways will be created. The CHROMTISOL solar cell concept bears a large potential to outperform existing thin film photovoltaic technologies and concepts due to unique combination of materials and their complementary properties. The project aims towards important scientific findings in highly interdisciplinary fields. Being extremely challenging and in the same time risky, it is based on feasible ideas and steps, that will result in exciting achievements. The principal investigator, Jan Macak, has an outstanding research profile in the field of self-organized anodic nanostructures and is an experienced researcher in the photovoltaic field";1644380;1644380;ERC-2014-STG;/ERC-STG;UNIVERZITA PARDUBICE;CZ;;;;1;0;0;1;0;0 203543;713010;GOAL-Robots;SIGNED;H2020-EU.1.2.1.;FETOPEN-1-2014;H2020;Goal-based Open-ended Autonomous Learning Robots;2016-11-01;2020-10-31;;"This project aims to develop a new paradigm to build open-ended learning robots called `Goal-based Open-ended Autonomous Learning' (GOAL). GOAL rests upon two key insights. First, to exhibit an autonomous open-ended learning process, robots should be able to self-generate goals, and hence tasks to practice. Second, new learning algorithms can leverage self-generated goals to dramatically accelerate skill learning. The new paradigm will allow robots to acquire a large repertoire of flexible skills in conditions unforeseeable at design time with little human intervention, and then to exploit these skills to efficiently solve new user-defined tasks with no/little additional learning. This innovation will be essential in the design of future service robots addressing pressing societal needs. The project will develop the GOAL paradigm by pursuing three main objectives: (1) advance our understanding of how goals are formed and underlie skill learning in children; (2) develop innovative computational architectures and algorithms supporting (2a) the self-generation of useful goals based on user/task independent mechanisms such as intrinsic motivations, and (2b) the use of such goals to efficiently and autonomously build large repertoires of skills; (3) demonstrate the potential of GOAL with a series of increasingly challenging demonstrators in which robots will autonomously develop complex skills and use them to solve difficult challenges in real-life scenarios. The interdisciplinary project consortium is formed by leading international roboticists, computational modelers, and developmental psychologists working with complementary approaches. This will allow the project to greatly advance our understanding of the fundamental principles of open-ended learning and to produce a breakthrough in the field of autonomous robotics by producing for the first time robots that can autonomously accumulate complex skills and knowledge in a truly open-ended way.";3481875;3481874,75;H2020-FETOPEN-2014-2015-RIA;/RIA;CONSIGLIO NAZIONALE DELLE RICERCHE;IT;"STIFTUNG FRANKFURT INSTITUTE FOR ADVANCED STUDIES;TECHNISCHE UNIVERSITAT DARMSTADT;UNIVERSITE PARIS DESCARTES";"DE;FR";;1;0;0;1;0;0 197368;674983;MIMIC;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2015-EID;H2020;Mimicking organs on chips for high throughput drug screening and basic research;2016-01-01;2019-12-31;;"MIMIC is an interdisciplinary European Industrial Doctorate at the interface of cell biology, engineering and drug development. MIMIC aims to develop and improve novel “organs on chips” technology. This technology combines modern cell biology with microfluidics and chip-based techniques with the goal to mimic organ functionality. There is a high demand by the pharmaceutical industry for more reliable tissue models to test drug toxicity and drug efficiency at early stages of drug development. Early reliable drug testing will have a major impact on drug development costs and human health. Furthermore, ethical considerations urge for the search for alternatives to replace animal tests in drug development and basic research. Organs on chips are a new exciting possibility to closer mimic human organ functionality in vitro than conventional 2D or 3D cell cultures. Organs on chips allow both, the emulation of healthy organs as well as the emulation of specific disease conditions using corresponding engineered or patient derived human cells. Moreover, organs on chips are ideally suited for high-throughput drug screening. The EID-MIMIC will develop novel organs on chips prototypes, and validate their suitability for end-users for high throughput drug screening or basic research. MIMIC will train early stage researchers in cutting edge technologies, like novel chip based technologies e.g. cell micropatterning, soft-lithography and microfluidics technology, as well as state of the art microscopy like super resolution- and confocal spinning disc microscopy and modern genome editing techniques like CRISPR-technology. In addition, MIMIC has developed a 3 year modular curriculum including workshops on creativity and business skills, summer schools, business plan competitions and international conferences with a specific agenda of transferable skill training elements highly relevant for scientific communication, translational research and, in particular, entrepreneurship.";1057324,32;1057324,32;H2020-MSCA-ITN-2015;/MSCA-ITN-EID;THE UNIVERSITY OF SHEFFIELD;UK;"MIMETAS BV;GALAPAGOS BV";NL;;1;0;0;1;0;0 195921;660275;LoStPReCon;CLOSED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Long-term structural performance of pre-stressed concrete bridges: A risk-based monitoring informed framework for life-cycle asset management;2015-11-01;2017-10-31;;"Recently, the re-assessment of the collapse of the Koror-Babeldaob Bridge (in 1996), a pre-stressed bridge built by the cantilever method, concluded that this was due to excessive deflections that appeared and grew non-linearly some years after construction. Interestingly, similar trends were found for a group of 56 similar bridge spans, raising the question whether such concerns could influence the maintenance and service life of a high number of pre-stressed bridges in Europe and beyond. Although individual material and structural factors have been researched, this problem can only be solved by integrating physical and probabilistic models and benefiting from the increasing use of monitoring data. This proposal aims to: 1.Review existing models for shrinkage and creep at specimen level, 2.Establish robust hybrid FE models for medium/long-term predictions, 3.Develop a novel monitoring approach based on Digital Image Correlation (DIC), 4.Formulate a time-dependent reliability assessment framework, addressing creep and shrinkage uncertainties, 5.Produce representative performance-time profiles for pre-stressed bridges based on the proposed framework and models. The above will be demonstrated via a case study – the Lezíria Bridge – possessing a unique combination of factors: (i) available monitoring data, (ii) pre-existing analysis models and (iii) an intimate knowledge by Dr. Helder Sousa, the researcher, of its construction and behaviour. The findings will be directly relevant to the growing number of bridges with this problem, enhancing the European knowledge and competitiveness in the global infrastructure market. For this, an interdisciplinary research and training programme has been set out, building on the researcher’s strong track record, expanding/honing his knowledge/skills, so that he can reach the forefront of highly qualified professionals able to solve problems in a creative/integrative manner, contributing to European expertise and wealth creation.";183454,8;183454,8;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;UNIVERSITY OF SURREY;UK;;;;1;0;0;1;0;0 195599;658375;EFTA DEVELOPMENT;CLOSED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;The ‘other’ Europe: the formation and development of the European Free Trade Association (EFTA), 1958–92;2016-01-01;2017-12-31;;Debates over the type and degree of integration pursued by European states currently dominate the European Union (EU). As the gulf between proponents and critics of the ‘Community method’ grows more acute, as the EU environment increasingly revolves around interstate relations, and as scenarios of EU ‘disintegration’ are entertained at various levels, attention has focused on historical precedents of intergovernmental models of cooperation in the hope of foreseeing the EU’s future development. Such debates have aroused notable interest in the European Free Trade Association (EFTA), the principal ‘other’ in postwar European politics. Yet very little is known about how and why EFTA developed in the way it did, its institutional and policy-making structure or the implications of these aspects for the present-day EU. The current state-of-the-art suffers two particular limitations: (i) it concentrates on very short time periods and (ii) it presents a highly state-centric realist account of EFTA’s history. This project fills this gap by undertaking a detailed historical study of EFTA’s development. It aims to (i) examine EFTA’s growth over a sustained period (1958–92) and (ii) account for this evolution as a product of interplay between actors at the national, transnational and institutional levels. Methodologically, the project deploys an innovative interdisciplinary approach that embeds historical research in the multi-level governance concept borrowed from political science. Empirically, the project draws on EFTA’s hitherto underexplored archives in Geneva and the national collections of its various member states. Historiographically, it promises new insights into EFTA history and reconnects the organisation’s and its members’ historical narrative to studies of European integration that generally focus more on the denser pre-history of the EU. In so doing, the project adds significantly to both research in the European Research Area and the priorities of Horizon 2020.;179325,6;179325,6;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;TURUN YLIOPISTO;FI;;;;1;0;0;1;0;0 195746;659222;SPAFIL;TERMINATED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Structured photonics for advanced fibre lasers;2015-07-06;2017-07-05;;"The key goals of the project are: (1) the training of a talented, independent researcher, Dr Amos Martinez, to become a successful leading scientist in the fast growing field of science, technology and industrial applications of fibre lasers, (2) exploring new ways to exploit two-dimensional materials, such as graphene, in photonics through femtosecond laser nanostructuring and developing new classes of light sources for applications in optical communications, medical imaging, industrial manufacturing and metrology. This multidisciplinary project has great implications on laser science, nanotechnology, material science and graphene technologies such as graphene plasmonics, metamaterials, phononics and electronics, and will involve both fundamental and applied research. The interdisciplinary training scheme is designed to enhance Amos’s expertise in photonics, strengthening his skills and helping him establish a research career in Europe. It covers component design and implementation, theoretical analysis, mathematical modelling and nanomaterial characterization. To assist Amos in reaching professional maturity and increase his exposure to academic and industrial collaborations, he will receive training on intellectual property management, funding and proposal writing, commercialization, business and finance management, and supervision and teaching. Secondments in academic and industrial co-hosts, with Prof. James R. Taylor (Imperial College, UK), Prof. Zhipei Sun (Aalto University, Finland), Xtera Communications (UK), Chromacity Lasers (UK) and Optoscribe (UK), are arranged to pursue scientific objectives, maximize Amos’s learning experience, expanding his network in Europe and maximising impact of research and training on EU industry. Exploiting his editorial experience at Nature, Amos will give seminars on effective scientific writing and engage with the public through outreach activities of the Physics Factory and the International Year of Light 2015.";195454,8;195454,8;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;ASTON UNIVERSITY;UK;;;;1;0;0;1;0;0 195527;657949;LOBFRAM;CLOSED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Lobbying and framing in foreign policy. EU and member states’ foreign policies towards Israel and Palestine;2015-09-01;2018-02-23;;"LOBFRAM aims to advance our understanding of lobbying and framing in foreign policy in the European Union’s (EU) system of multi-level governance. While lobbying in the EU has received a lot of attention in recent years, lobbying in foreign policy remains a largely under-researched topic. Therefore, this project will explore the activities of non-state actors (NSAs), such as business groups, NGOs and solidarity movements, in EU foreign policy, investigating the networks that are established at different levels (EU and member states) and framing processes. The main contribution of LOBFRAM will be to investigate networks as transmitters of ideas. In turn, this will help us to analyse how frames are created, get codified and become collective frames influencing foreign policy at both the EU and member state levels, as well as what mechanisms of mutual interaction exist between EU and national foreign policy positions. LOBFRAM will be based on an interdisciplinary approach building on international relations, EU studies, sociology and organizational studies and will rely on a mixed-methods approach. It will focus on the case study of the Israeli-Palestinian conflict, which is one of the most important policy issues on the EU and member states’ agenda, also in light of the strong commercial links with Israel, the crucial role as donors for the Palestinians and historical legacies. The project will zoom-in on three big member states, namely the United Kingdom, Germany and France, and identify similarities and differences among these member states as well as between them and the EU level when it comes to lobbying and framing activities. The findings of this project will be published in a monograph and two journal articles and widely publicized to a non-specialised audience via outreach activities (e.g. a dedicated website, one policy brief and activities for students).";173076;173076;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;FONDATION NATIONALE DES SCIENCES POLITIQUES;FR;;;;1;0;0;1;0;0 195169;655771;DiverseRoots;CLOSED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Drivers of Root Dynamics in Diverse Plant Communities;2016-01-01;2017-12-31;;"There is increasing evidence for the positive effect of greater plant species diversity on primary production, nutrient retention, erosion resistance and stability in response to changes. Many of these benefits can be directly related to the rooting system, however, biodiversity research to date has mainly focussed on aboveground responses. Recent methodological advances, including molecular methods to analyse the belowground distribution of different plant species to identify soil biota, and advances in tracer methodology now offer new opportunities to increase our insight in these belowground properties and their drivers. The objective of this project is to apply state-of-the-art methodology to 1) assess to what extent biodiverse vegetation improves rooting structure and b) elucidate the main drivers behind these rooting dynamics. The increased understanding of the belowground functioning of biodiverse systems has direct importance for many fields, including the sustainable intensification of agricultural systems and prevention of soil erosion. In a desk study, I will analyse existing root data in order to assess the differences in horizontal root distribution in monocultures compared to mixtures. This will feed into the design of an experimental root study carried out in the unique Phytotron facility of Radboud University, in which I will combine state-of-the-art molecular techniques with my own expertise in tracer techniques, to investigate root development in species’ mixtures and its drivers. This fellowship will be a perfect stepping stone in achieving my career goal to become a researcher at the top of the interdisciplinary field of plant-soil interactions in biodiverse systems. My quality as a researcher will be hugely improved by the new skills and deepened knowledge that I will acquire in this fellowship. My secondment at a Water Board will facilitate stakeholder interaction and dissemination in a field in which my research is directly applicable.";177598,8;177598,8;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;STICHTING KATHOLIEKE UNIVERSITEIT;NL;;;;1;0;0;1;0;0 195517;657865;MAXWELL;CLOSED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Maximising wellbeing and minimising emissions: backcasting social visions for a low-carbon Europe.;2015-09-14;2017-09-13;;The science of climate change demands radical long-term reduction in greenhouse gas (GHG) emissions. In supporting this, EU policy is committed to develop a low-carbon future by 2050 . Key to meeting this target is the contribution of energy and both analysis and policy development have been prioritised. The central planks of mitigation practices globally include technological change and efficiency. It is widely acknowledged that the challenge of mitigation fundamentally requires more , as emissions are dependent on the wider development path and underlying driving forces. Within these concepts exists not only the challenge of more complex analysis, but the opportunity of new ways to reduce energy consumption. A neglected but promising option is to look at the social structures underlying material consumption. The perception of mitigation policy is of cost and loss, but there is potential to deliver mitigation while improving peoples´ lives, to maximise wellbeing and minimise emissions. This study will backcast scenarios of social wellbeing in a low-carbon Europe of 2050 and how to achieve transition. It begins with the contested links between wellbeing and material consumption. The study is a first, adopting interdisciplinary alternative perspectives rather than a unifying theory. These perspectives will be used to develop an original contribution, different visions of desired social wellbeing in the EU of 2050. The energy implications of social scenarios entailing lower material consumption are unknown, this study is original in quantifying their contribution. An innovation follows by backcasting transition through European policy towards scenarios of future wellbeing and reduced emissions. The proposed study is novel and highly innovative addressing priority gaps in knowledge. It dovetails important contributions to energy research and European society and policy with development of the researchers´ career and shared benefits for the host institution.;179325,6;179325,6;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;TURUN YLIOPISTO;FI;;;;1;0;0;1;0;0 195548;658079;EMMA;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;European Multimodal Metaphor in Advertising;2015-10-05;2017-10-04;;Metaphor and metonymy are key tools in communication, particularly when abstract ideas or emotions are discussed. While extant literature addresses metaphor in language and images, little has dealt with the combination of metaphor and metonymy in the multimodal context of advertising, where they play a key role. The EMMA fellowship aims to redress this by testing figurative complexity and emotions, the impact of these on comprehension, accuracy of interpretation and advertising effectiveness. It involves an interdisciplinary study that combines cognitive and physiological psychology with linguistic and marketing interpretations. A mixed-methods approach of lab experiments and qualitative inquiry will assess the speed and depth of comprehension, the perceived appeal, and the physiological effect of static and video advertisements on participants from three linguistic and cultural backgrounds (English, Spanish, and Chinese). If advertisers, charities and NGOs target, and are sensitive to, linguistic and cultural differences in metaphors, local and international communities can benefit from specific, appropriate and ethical advertising. The fellow will benefit from involvement in a cutting-edge study and secondments both at a leading research institute in The Netherlands an two advertising companies in Spain.;183454,8;183454,8;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;THE UNIVERSITY OF BIRMINGHAM;UK;;;;1;0;0;1;0;0 195280;656511;KSHV QTV;CLOSED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Identification of novel KSHV immune evasion mechanisms using a quantitative temporal viromics analysis;2015-06-15;2017-06-14;;Kaposi’s Sarcoma-associated herpesvirus, or human herpesvirus 8, is an important cause of morbidity and mortality, causing tumors in immunosuppressed patients, in particular those with AIDS. Like other herpesviruses, KSHV has evolved numerous mechanisms of escape from both the innate and adaptive host immune response. These immune evasion strategies facilitate the virus’s oncogenic potential and contribute to its pathogenesis. Beyond immune modulation, many viral proteins interact with components of the cellular proteome to enable viral replication. However, the complete array of such proteins, their kinetics and fate in both latent and lytic phase of viral infection has never been determined. Here, I propose an unbiased proteomic approach to analyze the expression kinetics of the KSHV proteome in the context of cellular infection, and explore how host cell surface and cytoplasmic proteins are regulated by this virus throughout its infection cycle. To achieve this goal I will resolve both the host cell and the viral proteome in primary endothelial cells and B cells using the recently developed technique, quantitative temporal viromics. This novel approach is interdisciplinary, incorporating virology, immunology, cell biology, state-of-the-art proteomics and has been successfully applied to identify novel markers of latent HCMV infection as well as novel immunomodulation strategies. The proposed study will allow a temporal analysis of how the host and viral proteome change upon latent as well as lytic KSHV infection. Newly discovered viral targets, such as ligands for Natural killer (NK) or cytotoxic T cells will be validated and investigated using biochemical and virological methods available in the host (Lehner) lab. The results of this study will therefore provide unique insight into the virus-host interactions and uncover novel viral strategies of the host immune system. The identified proteins may ultimately serve as novel targets for therapeutic interventions.;183454,8;183454,8;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;UK;;;;1;0;0;1;0;0 201151;703516;TETRAPODBONES;CLOSED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Evaluations of bone strength in the evolutionary invasion of land by tetrapods;2016-08-22;2018-08-21;;"How tetrapods (vertebrates with digit-bearing limbs) became terrestrial is one of the most transformative yet enigmatic events in vertebrate history that set the stage for the diversification of tetrapods thereafter. Being on land imposes physical demands on the musculoskeletal system and weak bones can severely limit the capabilities of animals, yet the importance of bone strength in the evolution of terrestrial locomotion is not well understood. The proposed research integrates innovative approaches on the limbs of an early stem tetrapod, Ichthyostega, in order to: 1) quantify how well the limb bones in an early stem tetrapod could support locomotion on land, 2) compare the differences between the fore- and hindlimb bone mechanics, and 3) test the prevailing hypothesis that early stem tetrapods walked like extant salamanders. An interdisciplinary synthesis of cutting-edge techniques in engineering, 3D biomedical imaging, palaeontology, and biomechanics will be used to test the structural integrity of fossil limb bones in silico. Bone strength will be quantified with high-resolution ?-CT scans and finite element analysis, an engineering approach to estimate stresses and deformations in complex structures in response to physical demands. This novel dataset will address the ability of Ichthyostega to move on land, and what types of locomotor behaviours were not possible for an early stem tetrapod on land. Simultaneously, training and research activities in state-of-the-art engineering and 3D technology, evolutionary biomechanics, and public outreach will foster the development of the Experienced Researcher (ER) into an innovative and broadly trained researcher and science communicator. At a broader scale, tracing back the evolutionary steps to becoming terrestrial yields powerful insights into the tetrapod body plan, informing how ecological transitions influence functional innovation and how human anatomy is influenced by our ancestry from aquatic tetrapods.";183454,8;183454,8;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;THE ROYAL VETERINARY COLLEGE;UK;;;;1;0;0;1;0;0 200919;701075;RE-FRUIT;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;“Rehabilitation: Family Role within the UK in comparison to Turkey”;2016-08-01;2017-08-31;;"This fellowship will grow the participant's skills and experience in social aspects of rehabilitation. The research project aims to analyse the role of the family in in-patient and out-patient rehabilitation for disabled people in the UK and compare it with evidence previously gathered in Turkey. More widely, the sociology of rehabilitation is underdeveloped in disability research. Rehabilitation sciences have neglected the social and cultural dimensions of their work; conversely, disability studies has neglected the domain of rehabilitation. However rehabilitation is a key turning point in the lives of many disabled people. The role of the family is also of special importance, given the emphasis on independent living. This is especially so today, when neoliberal and austerity policies in the UK mean that state services are contracting and there is likely to be an expanding role for informal care and family support. The project will examine the role that families play in rehabilitation, the experiences of disabled people with such family involvement, and the situation for people who lack available family support, and compare the case of UK with the Turkish example. The project is designed as a qualitative case study, employing a variety of data collection strategies such as the use of participant observation, semi-structured interviews, focus groups, secondary sources, and the method of comparative analysis. This is an interdisciplinary project strengthened by the disciplines of sociology, philosophy, political science, and rehabilitation sciences, with the potential to make significant contributions to the fields of sociology of rehabilitation, disability studies and public policy. As well as the training dimension of the research (project management, focus group research, disability studies), the fellowship will also generate a research network proposal on post-conflict rehabilitation and integration research (enhancing European project writing skills).";99371,35;99371,35;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;UNIVERSITY OF EAST ANGLIA;UK;;;;1;0;0;1;0;0 199785;670851;AFRIGOS;SIGNED;H2020-EU.1.1.;ERC-ADG-2014;H2020;African Governance and Space: Transport Corridors, Border Towns and Port Cities in Transition;2016-01-01;2020-12-31;;"AFRIGOS investigates the process of 'respacing' Africa, a political drive towards regional and continental integration, on the one hand, and the re-casting of Africa's engagement with the global economy, on the other. This is reflected in unprecedented levels of investment in physical and communications infrastructure, and the outsourcing of key functions of Customs, Immigration and security agencies. AFRIGOS poses the question of how far respacing is genuinely forging institutions that are facilitating or obstructing the movement of people and goods; that are enabling or preventing urban and border spaces from being more effectively and responsively governed; and that take into account the needs of African populations whose livelihoods are rooted in mobility and informality. The principal research questions are approached through a comparative study of port cities, border towns and other strategic nodes situated along the busiest transport corridors in East, Central, West and Southern Africa. These represent sites of remarkable dynamism and cosmopolitanism, which reflects their role in connecting African urban centres to each other and to other global cities. AFRIGOS considers how governance 'assemblages' are forged at different scales and is explicitly comparative. It works through 5 connected Streams that address specific questions: 1. AGENDA-SETTING is concerned with policy (re-)formulation. 2. PERIPHERAL URBANISM examines governance in border towns and port cities. 3. BORDER WORKERS addresses everyday governance emerging through the interaction of officials and others who make their livelihoods from the border. 4. CONNECTIVE INFRASTRUCTURE looks as the transformative effects of new technologies. 5. PEOPLE & GOODS IN MOTION traces the passage of people and goods and the regimes of regulation to which they are subjected. AFRIGOS contributes to interdisciplinary research on borderland studies, multi-level governance and the everyday state.";2491364;2491364;ERC-2014-ADG;/ERC-ADG;THE UNIVERSITY OF EDINBURGH;UK;;;;1;0;0;1;0;0 195896;660143;CHAP;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;The transnational mobility of cheap print: British chapbooks in Italy, 1800-1850;2015-09-01;2017-08-31;;This action proposes mobility for an Italian researcher living in Britain to work in Ireland on a transnational historico-literary project. Her research focuses on the cross-cultural transfer of cheap print between Britain and Italy in the first half of the nineteenth century. The project advances existing knowledge of popular publishing and reading in two ways. Firstly, it contributes to the European historiography of cheap publications by extending the investigation of their production, distribution and reception to the Italian context. Secondly, and most importantly, it provides a concrete idea of the cross-cultural nature of cheap literature by exploring the mechanisms which regulate its migration from one linguistic and cultural realm to another. The transnational trajectory of cheap print is investigated with a focus on translation and on its potential to establish fruitful negotiations between the literary and cultural repertoires of the source and the target context. The project examines a corpus of chapbooks translated from English into Italian published between 1800 and 1850. The Italian chapbooks and their sources are analysed using an interdisciplinary approach which integrates theories of textuality, the history of the book and of reading, and translation studies. The comparative approach followed in my study will significantly enhance our understanding of popular literature and of the processes which led to the formation of a shared European heritage of popular culture. The multidisciplinary research environment at NUIG provides the ideal conditions for the researcher to develop this project and the skills necessary for her future academic career. The collaboration of Dr Niall Ó Ciosáin and the training that she will undertake in the history of the book will be particularly important to integrate her familiarity with translation and the eighteenth- and nineteenth-century Italian cultural context with new knowledge of popular publishing and reading.;175866;175866;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;NATIONAL UNIVERSITY OF IRELAND GALWAY;IE;;;;1;0;0;1;0;0 195882;660061;NCDIFFGEO;TERMINATED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Models of noncommutative differential geometries;2016-02-01;2018-01-31;;Quantum spacetime is the idea that spacetime coordinates are not classical variables but elements of a noncommutative 'co-ordinate algebra' much as in quantum theory. The first convincing models of (flat) quantum spacetime appeared in the 1990's, typically on the basis of quantum symmetry using the then-new theory of quantum groups. The thinking is that such noncommutativity should arise from quantum gravity effects and allows us to model these in an effective description without full knowledge of quantum gravity itself (this not being known). Such flat quantum spacetimes are an area of existing strength for EU science. The project proposes a new generation of quantum spacetime models no longer tied to quantum symmetry. Instead the Marie Sk³odowska-Curie Fellowship will train an experienced Researcher coming from theoretical physics in new highly algebraic tools which are not easily accessible to physicists and which amount to a mathematical theory of 'noncommutative Riemannian geometry' including quantum differentials, quantum metrics, and quantum-Levi Civita connections and quantum curvature. The realisation of the project will validate and enrich the mathematical formalism and also promises a next generation of physical effects related to the conjunction of both gravity and quantum noncommutativy, which will stimulate original and creative approaches to quantum gravity across several EU institutes. It will also greatly enhance the competitiveness of the Researcher in complementing her knowledge of theoretical physics by mathematics (noncommutative differential geometry) which will put her in a seminal position for subsequent work. The quality and ambition of the research objectives, the possibilities of interdisciplinary collaborations and the international recognition of the Supervisor will further enhance the action and the Researcher's career.;183454,8;183454,8;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;QUEEN MARY UNIVERSITY OF LONDON;UK;;;;1;0;0;1;0;0 196147;661734;PE4PPI;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Peer ethnography for the promotion of patient and public involvement: young people and sexual health service development.;2015-09-08;2017-09-07;;"This project will make an innovative contribution to patient and public involvement (PPI) in health through the application of an innovative peer ethnographic method, which offers the potential for new knowledge unobtainable through other qualitative research methods. A group of young people will be trained to conduct ethnographic research amongest their peers on gender relations, sexual initiation and behaviour, perceptions of sexual health services, and priorities for support. The team of peer researchers will be trained and supported in communicating the findings of their research with key stakeholders working in YP’s sexual health service provision in one region of the UK. The project will have several lasting impacts: it will provide important insight into the value of peer ethnography as a methodology to be used within PPI, contribute to new knowledge for evidence-based policy-making and service provision in the field of YP’s sexual health, and will equip a group of young people (YP) with important research, communication and advocacy skills. The project will enable the beneficiary to develop critical new skills and experience in the implementation and analysis of PPI in health, while at the same time broadening her interdisciplinary experience and expertise in applied anthropological research methods. She will also gain new skills in training and conducting research with YP. Dr White’s employability will be significantly enhanced through the tailored mentoring provided by her supervisor and other experts at the University of West of England (UWE) and the practical skills she acquires working on the proposed project. By the end of the Fellowship she will be equipped with the expertise and experience necessary to pursue an independent research position, enabling her to progress from the position of Research Fellow to Senior Lecturer, setting her firmly on the path of a professional academic career, towards an Associate Professorship and beyond.";195454,8;195454,8;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;UNIVERSITY OF THE WEST OF ENGLAND, BRISTOL;UK;;;;1;0;0;1;0;0 195724;659123;MOLMAG;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;New Spin for Molecular Magnets;2015-08-31;2017-08-30;;One of the next great challenges facing Europe is the development of new materials that reduce our dependence on critical metals such as rare earth elements (REEs). REEs have revolutionized both magnets and microelectronic industry, but the lack of economically exploitable deposits combined with geopolitical concerns have led to an impending resource problem. Molecular magnetic materials based on organic radicals represent one attractive alternative to REEs as the use of organic compounds would allow chemical processing rather than metallurgical. The challenge lies in developing radicals that are indefinitely stable under standard ambient conditions but still structurally tunable to attain the desired properties. This research project investigates two families of stable organic radicals and their metal complexes as new components for molecular magnetic materials. The radicals are based on the 1,2,4-triazinyl framework which, despite a long history and extreme stability, has only recently raised interest in materials oriented research. The potential of the investigated radicals will be exploited in two approaches. First, co-crystallization of the triazinyl radicals is studied as a novel design strategy to enhance intermolecular ferromagnetic interactions in organic radicals, and second, coordination of the radicals to paramagnetic metal centres is used as further means to control spin interactions through intramolecular spin coupling. The proposal combines the research ideas and synthetic skills of the experienced researcher with the knowledge and infrastructure of the supervisors and their hosting institutions, creating an interdisciplinary project that spans multiple fields from organic and organometallic synthesis to computational chemistry and condensed matter physics. Through the synthesis of new building blocks for real-world materials, the project will not only enhance the understanding of molecular magnetism but also the career development of the MSC fellow.;191325,6;191325,6;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;JYVASKYLAN YLIOPISTO;FI;;;;1;0;0;1;0;0 195584;658297;POLITICALLIFEWRITING;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;MASS POLITICAL LIFE WRITING;2015-09-01;2017-08-31;;"Self-narration is extraordinarily common in contemporary culture. The practice constitutes an extremely popular literary genre, is widespread on the internet in the form of diaries updated daily by huge numbers of web users, and is used in organisational training and as a tool in personal therapy education. Employing an interdisciplinary approach – drawing on social history, sociology, semiotics and textual analysis – my research project will examine one of the 'archaeological' elements underpinning this success: the mass political use of the autobiographical form, first by communism and subsequently by feminism after the Second World War, with a focus on the Italian experience. The Italian Communist Party (PCI) was the largest communist party in the Western world, and Italy’s experience of feminism is one of the most significant on the European continent. Both movements made intense political use of the autobiographical form. The Italian communists inherited the activist autobiographical framework characteristic of the Bolshevik experience. Self-narration was a prerequisite to joining the PCI until the second half of the fifties; however, this organisational practice became obsolete over the course of the sixties. The link between autobiographical accounts and political activism was subsequently revived by feminism in the seventies, in the context of consciousness raising groups. The main objectives of the project are the following: A) to analyse the mass political use of the autobiographical account in Italy since the Second World War; B) to use this analysis to produce an innovative interpretation of the actual success of self-narration. They will be fulfilled through research in the archives of the PCI and the Italian feminist movement. I will use Italian historical events as a case study to highlight the obscure political origins of a specific activity – self-narration – that unites various contemporary national cultures of Europe in a transnational manner.";195454,8;195454,8;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;THE UNIVERSITY OF MANCHESTER;UK;;;;1;0;0;1;0;0 195210;656089;FatherMotherland;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Fatherland as Motherland. Unstable Gender and Nation in Italian Great War Literature;2015-09-01;2017-08-31;;"'Fatherland as Motherland. Unstable Gender and Nation in Italian Great War Literature' is an interdisciplinary project exploring the interplay between nationalism and gender in Italian Great War literature. By tackling a diverse range of texts (pamphlets, prose fiction, memoirs, diaries, propagandistic publications), it will analyse gender patterns at work in Italian Great War literature and disclose their unstable relationship with nationalist ideology. WWI literature provides an extraordinary testing ground for exploring nationalist discourse in its ambivalences in that it absorbs its tenet, while reshaping it and releasing its instabilities. Such an approach proves highly needed: Italian WWI literature has been usually employed to describe the passage to the fascist period as if it were a homogeneous ideological set that could explain the rise of fascism. FatherMotherland will argue against both these premises (ideological stability of Italian WWI literature; its consistency with fascist culture) by means of an inquiry focusing on gender issues. The project will develop along three main lines: 1. The representation of manliness and virility; 2. The rhetorical features of the icon of the motherland; 3. The re-fashioning of the war literature canon in the fascist period. FatherMotherland has the ambition to foster a better understanding of the cultural roots of nationalism, which today threatens the process of European integration.";183454,8;183454,8;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;THE UNIVERSITY OF EDINBURGH;UK;;;;1;0;0;1;0;0 195112;655459;PleisTechnoVar;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Technological Variability during the Late Pleistocene in Eastern Africa: lithic assemblages as indirect witnesses of past human population dynamics;2015-10-01;2017-09-30;;"PleisTechnoVar aims to better understand the increase in technological variability observed in Africa during the Late Pleistocene, between 70000 and 15000 years ago. While many research projects have focused on the origins of Homo sapiens and its spread Out of Africa into Eurasia, fewer research has concerned the material cultures of the populations who « stayed » in Africa and how they interacted with eachother. The first objective is to study this variability on the regional scale of Eastern Africa, between Kenya and Ethiopia. The second objective is to develop a methodological approach to understand the factors driving this variability. A larger scale of analysis will be used and Eastern Africa as well as the Nile Valley and the Levant will be considered in order to propose hypotheses concerning links between technological variability, environments and population dynamics. This project is an in-depth study of the candidate's previous research axes in these regions. In order to meet these objectives, lithic assemblages will be studied using the concept of chaîne opératoire and attribute analyses. Data collection will take place during short mobilities in museums in Eastern Africa, Israel and Europe. Spatial analyses will complete the study. These data will then be discussed in view of the known palaeoenvironmental data, as well as the results from the study of other types of material (zooarchaeology, geomorphology, etc.). The research will be conducted at the McDonald Institute for Archaeological Research in the University of Cambridge where the candidate will receive high level training to improve her skills in the study of material culture (quantitative and qualitative data, theoretical background), as well as to develop new competences in spatial analysis (through the use of Geographic Information Systems (GIS)). The candidate will greatly benefit from the host organisation's experience in interdisciplinary research on the diversity of material cultures.";183454,8;183454,8;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;UK;;;;1;0;0;1;0;0 194989;654731;ARD-West;CLOSED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Ancient Religious Dedications in the Western Mediterranean Basin;2015-09-01;2017-08-31;;"Ancient European cultural features are made up of epichoric creations, transfers and even local adaptations. Before Roman domination led to a new, centralised kind of cultural context, numerous peoples had developed their own cultural and identity codes through creation, adaptation and re-elaboration of concepts and objects. The goal of this project is to identify these processes of creation in Pre-Roman peoples' written expression. An innovative criterion has been chosen to accomplish this challenge, that is, the epigraphical genre (EG), whose definition through its material and textual elements (ME and TE) we have developed, and we will refine through this project. A particular kind of EG, the religious dedication (RD), is our starting point due to their wide diffusion and their significance in identity matters. We believe that the epigraphical approach is idoneous to achieve this aim, given its holistic results and its multidisciplinar methodology. It also involves a direct analysis of the pieces, which contributes preserving European archaeological, linguistic and religious heritage. All the results will be stored in an updated, accesible online epigraphical DataBase of all the Pre-Roman and early Roman RD in the Roman West, which will facilitate knowledge transfer at all levels and on which our further research will be based. The proposed interdisciplinary research combines the linguistic and socio-linguistic approach, led by Dr. Emmanuel Dupraz (the supervisor), with the historical/epigraphical perspective, provided by Dr. María José Estarán (the ER) at the Université Libre de Bruxelles (ULB).";160800;160800;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;UNIVERSITE LIBRE DE BRUXELLES;BE;;;;1;0;0;1;0;0 195411;657227;DoRoThy;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Donating Robots a Theory of Mind;2015-09-07;2017-09-06;;"This project aims to advance the science and technology of meta-cognition in social robotics. During social interactions, humans use powerful cognitive mechanisms to represent and interpret what others know or intend. Doing so helps us respond appropriately in social interactions: we use a combination of sensory perception together with internal models of what others are (and will be) doing and thinking. We believe these capabilities to be equally important for social robots, a type of robot which is intended to interact with people. Endowing robot with skills to 'read the minds' of others is not only key to build next-generation assistive and industrial robots, but also presents a considerable research challenge. A challenge with tremendous benefits but few successes to date. Relying both on a novel formal approach based on modal logics, and on a strong experimental component in real-world conditions, this proposal suggests an ambitious interdisciplinary approach to better comprehend and formalize higher-order artificial cognition. The aim of which is to advance the design and practical implementation of socially interactive robots, in line with the Horizon 2020 Future and Emerging Technologies priority of moving 'cognition beyond problem solving'.";195454,8;195454,8;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;UNIVERSITY OF PLYMOUTH;UK;;;;1;0;0;1;0;0 195342;656848;NETIA;CLOSED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Neolithic textiles and clothing industries in the Aegean;2015-09-01;2017-08-31;;"The NETIA research project explores the textile arts and crafts of the early agricultural communities in the Aegean (6500-3300 BCE). The scope of this interdisciplinary project is to examine the origins and the first stages of textile crafts and other related technologies for coverage, protection and decoration of the human body. It focuses on raw materials, tools, technologies and textile design but aims towards an understanding of spatial organization of crafts and its impact on the economy, social structure of ancient societies and their natural environment. The main data collection will be carried out primarily within the borders of the modern Greek state, while comparisons will be made with Neolithic evidence from the Balkan countries and Anatolia. Since industrial activities in the Neolithic societies are closely related to the earliest systematic exploitation of natural resources and the domestication of wild species (plants and animals) first attested in the Near East, this synthesis, combined with other archaeological data, will contribute to an overall understanding of innovations, cultural exchange and population mobility in contemporary Neolithic Europe. The project is hosted by the University of Copenhagen’s Centre for Textile Research (CTR), a highly specialized center for textile studies with rich activity and international collaborations providing optimal training for the project's purposes, and by the TOPOI Excellence cluster ‘’Textile Revolution in FU Berlin. The results will be presented in a series of academic and popular outreach activities and will supply material for educational and industrial applications.";200194,8;200194,8;H2020-MSCA-IF-2014;/MSCA-IF-EF-CAR;KOBENHAVNS UNIVERSITET;DK;;;;1;0;0;1;0;0 195240;656273;RContext;CLOSED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Radical Contextualism and the Science of Meaning;2015-09-01;2017-12-16;;"The project investigates the impact that ‘radical contextualism’ (RC) has upon certain foundational issues in the philosophy of language, formal semantics, and philosophy of science. What motivates RC is the idea that our interpretation of a word, and what we refer to by using it, might be very different on different occasions of use. This suggests that our ability to interpret words, or to understand what they mean, depends in part on our being familiar with certain features of the occasions on which words are actually put to use. However, since communicative occasions are not systematically tractable, this seems to render systematic theories of meaning impossible. My chief objective is to think of a way out of this difficulty whilst taking the intuition behind RC seriously. The key proposal I aim to develop and defend is that RC does not militate against the possibility of constructing theories of meaning, as is commonly assumed. Instead, what RC does challenge are the ontological commitments typically inherited by such theories; e.g. commitment to the existence of objects that are supposed to play the role of stable semantic values of open-class linguistic expressions. My novel response to the challenge from RC will be to propose two ontologically neutral metasemantic frameworks: dynamic content externalism and methodological internalism. I shall assess main hypotheses on the case of natural kind terms. The project is interdisciplinary, combining insights and techniques from philosophy and formal semantics. I have a background in philosophy of language but I have no training in formal semantics or theoretical linguistics. Hence, this project, supervised by Prof. Martin Stokhof (ILLC) who specialises in dynamic semantics, represents a remarkable opportunity for me to acquire new formal skills, which will not only be necessary for carrying out the proposed research, but also very important for my future career development.";177598,8;177598,8;H2020-MSCA-IF-2014;/MSCA-IF-EF-CAR;UNIVERSITEIT VAN AMSTERDAM;NL;;;;1;0;0;1;0;0 207074;736879;IVALO;SIGNED;"H2020-EU.2.1.5.;H2020-EU.2.1.3.;H2020-EU.2.3.1.;H2020-EU.2.1.2.";SMEInst-02-2016-2017;H2020;Europe to lead the way in revolutionary information lighting solutions;2017-01-01;2017-06-30;;Considerable team experience and interdisciplinary know-how has resulted in a novel innovation, known as Ivalo. The Ivalo project is a unique undertaking focused on combining proprietary nanomaterials with advanced manufacturing and processing techniques, to deliver new possibilities for high volume, high growth, informational display solutions in global markets.;71429;50000;H2020-SMEINST-1-2016-2017;/SME-1;BRIGHTPLUS OY;FI;;;;1;0;0;1;0;0 204810;694105;HERITAGE;SIGNED;H2020-EU.1.1.;ERC-ADG-2015;H2020;Monumental Art of the Christian and Early Islamic East: Cultural Identities and Classical Heritage;2016-09-01;2021-08-31;;"This project will analyse the monumental art (large decorative programmes on buildings) of two areas of the former eastern Roman Empire which came under Islamic rule but which have never been the subject of an integrated comprehensive study: Egypt and Syro-Palestine (modern Syria, Jordan, Lebanon, and Israel/Palestine). It aims to determine systematically how the strength and nature of the local ‘classical’ (Greco-Roman) traditions and expressions of identities influenced monumental art in these regions during Late Antiquity (AD 250–750), the period of transition from paganism to Christianity and, in turn, to Islam. By defining and distinguishing between the different strands of classical influence, both local and external (from the centres of Rome, Constantinople, and Alexandria), and investigating the roles of local artists and artisans as creators rather than imitators, this project will transform our understanding of the artistic culture of the late antique Middle East. To achieve these objectives, this 5-year project, with a team of 4 post-docs, will apply an interdisciplinary methodology, using archaeology, architecture, art history, and textual analysis to examine evidence in a range of media (floor and wall mosaics, paintings, relief sculptures). The results will be presented in a synthetic analytical volume written by the PI and two books on late antique and early Islamic mosaics by the post-docs, with material placed on the Manar al-Athar open-access website. Monumental art is the most visible surviving artistic heritage in the Middle East, on major buildings such as the Dome of the Rock in Jerusalem, the Great Mosque in Damascus, ‘desert castles’, and church mosaic floors. This art is increasingly endangered, so it is essential to undertake this project now to show the importance of this art, the roles of ancestors of peoples of the Middle East in its creation, and the shared classical heritage of the Middle East and the West.";2350533;2350533;ERC-2015-AdG;/ERC-ADG;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;UK;;;;1;0;0;1;0;0 203990;702884;SOFIA;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Situated Learning Opportunities fostered by ICT applications in Alternative Agro-Food Networks;2016-06-01;2018-01-31;;"The training-through-research project SOFIA - Situated Learning Opportunities fostered by ICT applications in Alternative Agro-Food Networks- aims at enhancing the researcher potential to make broad his horizons and support his career development. In the light of his research objectives he will acquire new knowledge and transfer that one previously developed to the host organization The SOFIA project will allow the ER to became a key facilitator of multidisciplinary research and innovation teams, applying his interdisciplinary competences in service design for innovation, thus ensuring an independent position to the researcher and his future employability in the academic and/or non-academic context. The research SOFIA aims to analyze innovative organizational models and explore the value of the use of ICT tools (e.g. ubiquitous mobile services) to increase Situated Learning Opportunities (SLOs) in an Alternative Agro-Food Networks (AAFNs), through two methodologies i.e multi-case study analysis of local food systems and rural areas and a web-survey of ICT tools for AAFN. The expected impact of the research is to define a set of reproducible methodologies, models, tools and technologies that can improve the competitiveness of a selected area, leveraging its potential in terms of materials and intangible resources. In addition, the study will aim to analyze ICT tools supporting the information flows management both for decision making and for operational processes in the identified collaborative networks. The researcher will carry out specific actions to disseminate project results and increase their fruitful exploitation, e.g.SOFIA’s results will be exploited to draw up guidelines based on innovative organizational models, tools and ICTs to support the dynamics of sustainable development in local food systems and to design and develop Mobile services to support SLOs in AAFNs in order to improve mutual understanding and collaboration between value chain stakeholders.";162879;162879;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;UNIVERSITY OF GLOUCESTERSHIRE LBG;UK;;;;1;0;0;1;0;0 200399;704528;POSE;CLOSED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Poetics of Statelessness in Twentieth-Century France and Europe;2016-09-01;2017-08-31;;Offering the first comprehensive analysis of the phenomenon of statelessness in the context of twentieth-century French-language and European poetry, this project will result in two outputs / activities. These are: i) a monograph publication devoted to four important French-language poets of the period who engage with the problematic of statelessness and ii) an international workshop entitled ‘The Language of the Stateless’ exploring the theme’s pertinence within modern and contemporary poetry in a broader European context, leading to publication of a volume which the experienced researcher, Dr Greg Kerr, will edit. The monograph blends theoretical discussion (based on philosophical sources such as those by Jacques Ranci?re and Hannah Arendt) with digitally-informed textual analysis, focussing on the specific linguistic features of works by four poets: Armen Lubin, Gherasim Luca, Edmond Jab?s and Michelle Grangaud. It will draw significantly on intellectual and institutional resources in digital textual databases and the study of modern poetry and language acquisition at the Analyse et Traitement Informatique de la Langue Française research laboratory, part of the Centre National de la Recherche Scientifique, Nancy, France. The workshop and subsequent publication will provide a much-needed networking opportunity for European researchers who are working on statelessness, modern poetics and intercultural experience in their specific national contexts. Each strand of the project draws significantly on digital humanities resources and combines elements of individual interdisciplinary research, skills training and public engagement activities.;86538;86538;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FR;;;;1;0;0;1;0;0 200704;677758;CREWS;SIGNED;H2020-EU.1.1.;ERC-StG-2015;H2020;Contexts of and Relations between Early Writing Systems;2016-04-01;2021-03-31;;"Contexts of and Relations between Early Writing Systems This project takes an innovative and interdisciplinary approach to the history of writing, redressing lingering problems that have hampered previous research and developing new methodologies for studying scripts and their social context. The staff on the project will work on specific case studies relating to inscriptions of the ancient Aegean, Eastern Mediterranean and Levant (c.2000-600 BC), developing a new and much deeper understanding of writing, literacy and social and cultural interrelations in the area than has ever been possible via the often out-dated traditional methods usually applied to these data. The focus will be on enriching our understanding of both linguistic and social aspects of the borrowing and propagation of writing. This planned research has the potential to change the way we think about writing systems, their societal context and the ways in which ideas were exchanged in early civilisations. Published and publicised through multiple outputs and media, the results will be of importance not only to the specific chronological period and geographical area under close consideration but also to the diachronic study of relationships between population groups and the significance of such relationships for the wider field of cultural history.";1472519;1472519;ERC-2015-STG;/ERC-STG;THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;UK;;;;1;0;0;1;0;0 198293;675440;AMVA4NewPhysics;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2015-ETN;H2020;Advanced Multi-Variate Analysis for New Physics Searches at the LHC;2015-09-01;2019-08-31;;"With the 2012 discovery of the Higgs boson at the Large Hadron Collider, LHC, the Standard Model of particle physics has been completed, emerging as a most successful description of matter at the smallest distance scales. But as is always the case, the observation of this particle has also heralded the dawn of a new era in the field: particle physics is now turning to the mysteries posed by the presence of dark matter in the universe, as well as the very existence of the Higgs. The upcoming run of the LHC at 13 TeV will probe possible answers to both issues, providing detailed measurements of the properties of the Higgs and extending significantly the sensitivity to new phenomena. Since the LHC is the only accelerator currently exploring the energy frontier, it is imperative that the analyses of the collected data use the most powerful possible techniques. In recent years several analyses have utilized multi-variate analysis techniques, obtaining higher sensitivity; yet there is ample room for further improvement. With our programme we will import and specialize the most powerful advanced statistical learning techniques to data analyses at the LHC, with the objective of maximizing the chance of new physics discoveries. We aim at creating a network of European institutions to foster the development and exploitation of Advanced Multi-Variate Analysis (AMVA) for New Physics searches. The network will offer extensive training in both physics and advanced analysis techniques to graduate students, focusing on providing them with the know-how and the experience to boost their career prospects in and outside academia. The network will develop ties with non-academic partners for the creation of interdisciplinary software tools, allowing a successful knowledge transfer in both directions. The network will study innovative techniques and identify their suitability to problems encountered in searches for new physics at the LHC and detailed studies of the Higgs boson sector.";2393361,31;2393361,31;H2020-MSCA-ITN-2015;/MSCA-ITN-ETN;ISTITUTO NAZIONALE DI FISICA NUCLEARE;IT;"UNIVERSITE CLERMONT AUVERGNE;INSTITUTE OF ACCELERATING SYSTEMS AND APPLICATIONS;TECHNISCHE UNIVERSITAET MUENCHEN;UNIVERSITE CATHOLIQUE DE LOUVAIN;LABORATORIO DE INSTRUMENTACAO E FISICA EXPERIMENTAL DE PARTICULAS;UNIVERSITA DEGLI STUDI DI PADOVA;UNIVERSITE BLAISE PASCAL CLERMONT-FERRAND II;EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD";"FR;EL;DE;BE;PT;IT;CH;UK";;1;0;0;1;0;0 197889;656701;NuFEAST;CLOSED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Optimising Nutritional Health and Wellbeing Through Local Sustainable Food Systems -NuFEAST (Nutrition - Food (for) Everyone's health, Available, Sustainable and Trusted);2015-09-02;2017-09-01;;The WHO European Region has the highest incidence (and increasing) of obesity and non-communicable diseases (including type 2 diabetes, cardiovascular diseases and food related cancers) caused by dietary factors. Localisation of sustainable food systems and processes that comprise a sustainable diet is a possible means to tackle this problem. There is a need to develop new research approaches to identify how these initiatives can promote nutritional well-being, to shape future nutrition and food policy and to document the new skills required by the public health nutrition workforce to support and foster healthy diets. This project will capitalise on the complementary expertise of the Fellow (with extensive practice experience in Australia and New Zealand as a community nutritionist) and the interdisciplinary research skills and expertise at Bournemouth University (BU) to generate new knowledge and understanding of the contribution of local food sustainable systems to nutritional health and well-being. This will be a unique, systematic research programme that combines quantitative and qualitative research methodologies which will enable first steps for the design of a model of nutritional health and well-being and identification of new competencies for training in public health nutrition. The key outcomes of this research will be i) a Toolkit for monitoring and optimising gains in nutritional health and well-being and ii) new Guidelines to deliver new competencies for the public health nutrition workforce. This knowledge will contribute towards shaping future policy directions in food and nutrition for EU citizens. The Fellow will be up-skilled (in new research skills and techniques) to advance her career significantly, to translate her background knowledge into a continuing research environment and to build and maintain links with other public health researchers in sustainable food environments throughout Europe, while maintaining strong links in Australia.;195454,8;195454,8;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;BOURNEMOUTH UNIVERSITY;UK;;;;1;0;0;1;0;0 195649;658846;Rotary Wing CLFC;TERMINATED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Closed-Loop Flow Control to Enhance Aerodynamic and Aeroacoustic Performance of Wind-Turbine Blades;2015-05-01;2017-04-30;;Aerodynamic loads and noise emitted from rotating blades are of interest in many industrial applications, such as wind-turbines, aircraft propellers, helicopter blades, and cooling fans. This research project aims to achieve, for the first time, a combined aerodynamic and aeroacoustic optimization of rotary wing by experiments conducted in a controlled environment of gusting flow and rotating motion. In the current work focus will be made on wind-turbine applications. Both passive and active flow control technologies will be utilized to enhance the amount of energy harvested from the wind, while improving the aeroacoustic properties. Leading- and trailing-edge serration have proven to be effective in reducing the noise emitted from wind-turbine blades. However, their effectiveness under realistic flow conditions in a controlled environment has not been investigated. These experiments will be used for further development and validation of new aerodynamic and aeroacoustic models. The ultimate and final goal is to apply closed-loop flow control by utilizing a physics based model. Alongside these experiments, innovative and stand-alone technology for data acquisition and control in rotating blade environments will be developed and implemented. This holistic interdisciplinary approach, bringing together the aerodynamic and aeroacoustic behaviour of wind-turbine blades under realistic flow conditions into one comprehensive study is unique and novel, and will lead to major advances in our understanding of rotating blades aerodynamics and aeroacoustics.;171460,8;171460,8;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;TECHNISCHE UNIVERSITAET BERLIN;DE;;;;1;0;0;1;0;0 195660;658849;Mycena;CLOSED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Unraveling the ecology of a widespread fungal group by genomic, isotopic and physiological analyses;2015-08-01;2017-07-31;;This proposal aims to shed light on the life strategy of Mycena (or bonnet mushrooms), a widespread group of macrofungi and with important functions in forests and other terrestrial ecosystems. While its members have traditionally been uniformly assumed to be degraders of litter, wood and other dead biological matter, very recent research has suggested that several members could in fact be parasitically or mutualistically biotrophic with plants. In numerous studies, environmental sequences with affinity to Mycena have been observed associated with plant roots. To solve this puzzle, we will use a multifaceted, interdisciplinary approach where we combine traditional knowledge about fungal cultivation with advanced DNA sequencing technology and isotope analyses techniques. The rapidly developing high throughput DNA sequencing technology (HTS) produces millions of DNA strands within hours, and by applying this to plant roots, we will quickly obtain an overview of the presence of Mycena in or on plant roots (indicating a possible biotrophic relationship). We will create a database of Mycena sequences from our own sequencing as well as sequences already publicly available. By sequencing the entire genome of five carefully selected species of Mycena, we will be able to analyse the genomic content associated with different life strategies. As molecular identification of Mycena associated with plant roots does not indicate an ecological interaction per se, we will employ innovative research techniques designed to quantify potential interactions. Isotopic fractionation of carbon/nitrogen of Mycenas and plants at field sites can reveal the mushroom´s source of carbon, and co-culturing of biotrophic Mycenas together with plants will provide direct evidence for the nature of their relationship(s). This research will clarify the ecology of a prominent and widespread genus of fungi, thereby illuminating its role in forest and general plant ecology.;208400,4;208400,4;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;UNIVERSITETET I OSLO;NO;;;;1;0;0;1;0;0 195702;659008;SocForVul;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;The impact of supplementary feeding on the food searching strategies and social behaviour in anendangered top scavenger;2015-09-01;2017-08-31;;The provision of surplus food at supplementary feeding stations is a worldwide practice to facilitate the recovery of endangered species like vultures, which have experienced dramatic population declines during the past century. Despite considerable research on the effects of supplementary feeding on the viability of populations, there is almost a total lack of knowledge on the effects of these practices at the individual level. In the proposed project (Social Foraging in Vultures, “SocForVul”), I will use the newest advances in bio-logging techniques to investigate the impact of supplementary feeding on food searching behaviour (via GPS/acceleration data-logging) and the social dynamics (via proximity data-logging) of the endangered Canary Egyptian Vulture. This research project aims to combine concepts from the fields of Animal Personality and Social Network Theory, using cutting-edge analytical techniques, to quantify the relative ability of individuals to cope with human-induced environmental changes. The Fellowship will provide me with a unique opportunity to deepen my knowledge on consistent individual differences in behaviour and expertise in the use of modern technology for field research, improve my analytical skills, and develop new expertise in behaviour-based wildlife management. Performing my research at The Do?ana Biological Station, which is one of the best research locations in Europe for fundamental research and conservation, will guarantee high quality training and excellent research output. The proposed research holds excellent prospects for interdisciplinary collaborations and career opportunities. Finally, from a conservation point of view, information on the impact of supplementary feeding on the social life of vultures will undoubtedly improve current guidelines for this conservation strategy and help sustaining healthy populations of scavengers as well as maintaining important ecological and evolutionary processes.;170121,6;170121,6;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS;ES;;;;1;0;0;1;0;0 195711;659046;MACROIMAGING;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Specific Fluorogenic Peptides for Imaging Metastasis-associated Macrophages;2015-10-01;2017-09-30;;"MACROIMAGING is a highly interdisciplinary project encompassing the preparation and optimisation of innovative fluorogenic imaging tools with high selectivity for metastasis-associated macrophages. The metastatic potential of tumours is defined by the tumour microenvironment (TM), where macrophages are the most abundant cells. However, the role of macrophages in the TM remains elusive mainly because of the lack of technologies to target these unique populations of cells in vivo. CD11b\ metastasis-associated macrophages are recruited by metastasing cancer cells. Their depletion reduces the number and size of metastasis, suggesting that their recruitment is essential for persistent growth of cancer cells. However, there is a need for imaging tools that report the localisation and cell fate of these macrophages to understand how they help tumour cells to progress in the TM. By means of Dynamic Combinatorial Chemistry, libraries of cyclic peptides will be generated from individual tetrapeptides through reversible disulfide bonds. Governed by thermodynamics, DCC will amplify cyclic peptides showing high affinity for CD11b\ macrophage receptors, involved in the development of metastasis. This technique will supply specific cyclic peptides targeting CD11b. Click chemistry (i.e. CuAAC) will allow the conjugation of these peptides to macrophage-specific fluorophores to generate FLUOROMACS. FLUOROMACS will enable selective imaging of CD11b\ macrophages by means of receptor-mediated endocytosis. Selectivity will be confirmed in vitro using macrophages from normal cohorts and knockouts. Finally Fluoromacs will be optimised as in vivo imaging probes for metastasis-associated macrophages. In a nutshell, MACROIMAGING will provide the first generation of chemical probes for imaging metastasis-associated macrophages in vivo. This methodology will also have enormous impact in other areas of chemical biology, such as protein recognition, drug discovery and theranostics.";183454,8;183454,8;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;THE UNIVERSITY OF EDINBURGH;UK;;;;1;0;0;1;0;0 195718;659092;WISDOM;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Wavelength conversIon in diSpersion engineereD Optical fibres for Mid-IR applications;2015-06-01;2017-05-31;;"Numerous high impact applications, in particular in medical diagnostics, environmental and industrial sensing would benefit from the development of wavelength-agile and cost-effective optical sources and detection schemes operating in the Mid-Infrared (MIR) region above ~2 µm wavelength. Existing MIR semiconductor technology and bulk nonlinear optics based solutions present many drawbacks and only partially meet the requirements of MIR applications. A more powerful and versatile approach to access the MIR spectrum relies on exploiting microstructured optical fibres (MOFs) made of MIR transmitting glasses. By exploiting nonlinear processes inside carefully designed fibres, MIR radiation can in principle be generated or detected using more mature Near-Infrared (NIR) sources or detectors. This approach offers three significant practical advantages: 1) it is wavelength-agile and reconfigurable; 2) it uses cost-effective and performant NIR source/detector technology; 3) it can generate compact, ruggedized and light-weight all-fibre devices. Despite a great potential, MIR nonlinear fibres are still a rather immature technology, due to the difficulty to fabricate fibres with suitable dispersive profiles in glasses with good infrared transmission. This task requires interdisciplinary skills in fields ranging from glass science, electromagnetics and waveguide modelling, to laser and nonlinear physics and experimental optics. This fellowship project will provide the opportunity to combine my glass science expertise with the host institution world-renown experience in nonlinear optics and MOF fabrication, with the aim to push MIR nonlinear fibre devices from an academic interest to a real technological reality. The project will target three enabling fibre devices and their use in high-impact applications: a coherent MIR supercontinuum source and two frequency conversion fibre devices for MIR gas sensing and telecoms interband wavelength conversion.";183454,8;183454,8;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;UNIVERSITY OF SOUTHAMPTON;UK;;;;1;0;0;1;0;0 194880;653639;KMET-READ;CLOSED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Reading of lysine methylation – discovery, biological function and application;2015-10-01;2017-09-30;;Protein methylation at lysine residues modulates chromatin structure, affects gene expression and mammalian development. Recently, it was also shown to influence the stability and activity of non-histone proteins. Lysine methylation marks manifest their biological effect via so-called ‘readers’ (or reading domains) which recognize and bind the methylation mark and directly alter the chromatin structure or act as a scaffold for other proteins, which induce biological responses. Reading domains include Plant homeodomains (PHD) and Chromodomains (CD) found in many chromatin proteins. KMET-READ plans to investigate the biological role of these reading domains in essential histone lysine methyltransferases - PHDs in MLL2 and MLL3 and CDs in SUV39H1 and SUV39H2. The results obtained here will advance the understanding of chromatin changes in human cells. The proposal will apply an interdisciplinary approach in an international environment to maximize its chances of success: the biological role of reading domains will be evaluated with molecular biology (histone and chromatin pulldowns, ChIP-seq, confocal microscopy), biochemistry (Peptide arrays, mass spectrometry, methyltransferase activity assays) and biophysics techniques (fluorescence anisotropy, circular dichroism spectroscopy) as well as crystallography (solving the structure of reading domains). Importantly, the KMET-READ project will also develop a yeast-3-hybrid method for the identification of new reading domains, which will allow to discover binding partners for just recently characterized new protein methylation marks. This novel method will be patented and introduced into market. All project partners will ensure an efficient dissemination and communication of the results of the KMET-READ project. The project will provide excellent training in research methods and other skills for the fellow that will strongly support her future career and initiate new and sustainable collaborations between the partners.;171460,8;171460,8;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;UNIVERSITAET STUTTGART;DE;;;;1;0;0;1;0;0 195458;657505;MTT;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;How does future thinking work? Uncovering its evolutionary and developmental origins;2015-09-01;2017-08-31;;"Time is always moving forward. However, humans can remember past events (e.g., our last holiday), and imagine and plan for events that have not happened (e.g., our next job interview); that is, we can mentally travel back into our past (i.e., episodic memory) and our future (i.e., future thinking). Having a comprehensive picture of this capacity involves not only studying Mental Time Travel (MTT) in humans but also in non-human animals. Due to conceptual and methodological limitations, the field of MTT is still in its infancy. Comparative and interdisciplinary studies—involving more than one animal species— are needed to understand the evolution and development of this capacity. I aim to address this issue by developing two novel empirical approaches to test how non-human primates (chimpanzees), corvids (rooks) and human children use information about past events to think and imagine future events. The results of this research will provide crucial insights for theories of cognitive development (e.g., the relation between theory of mind, executive functioning and mental time travel) and human evolution (e.g., the role of mental time travel in humanity’s ability to build upon knowledge or skills generation after generation). In this sense, broadening my theoretical background and acquiring new methodological skills (e.g., testing new animal species)—as I plan to do during this fellowship—will be of crucial importance for me to further develop my career.";183454,8;183454,8;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;UNIVERSITY OF NEWCASTLE UPON TYNE;UK;;;;1;0;0;1;0;0 195042;655075;FAST-RAP;CLOSED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Structure-function studies of the human FASTK family of mitochondrial proteins with putative novel RNA binding domains – the helical FAST motifs and the small RAP domain;2015-10-01;2017-09-30;;The purpose of this project is three-fold. The main aim is to elucidate the structure of two novel RNA binding folds: the helical FAST motifs and the small RAP domain that are predicted in the Fas-activated Serine/Threonine Kinase (FASTK) protein family. To this purpose, I will employ protein crystallography and small angle X-ray scattering to obtain models of FASTK proteins and their domains. The second objective is to understand the function of the FASTK family of mitochondrial RNA-binding proteins that were originally annotated as atypical kinases. The eponymous FASTK engages in processes similar to its interaction partner, the post-transcriptional regulator TIA-1, whereas some of the other five human paralogs are necessary for cellular respiration. I will use purified FASTK proteins to study their enzymatic activities and RNA-binding properties in vitro, which should clarify their functional classification as kinases or post-transcriptional regulators. Additionally, follow-up studies may include validation of the findings through informed mutagenesis, identification of RNA targets, protein partners, and selected phenotypes in RNA biology. The final goal of this project is to enable a young researcher to establish herself as an independent researcher, creating a group which will focus on mitochondrial RNA-binding proteins and employ X-ray crystallography as the main tool. Altogether, this interdisciplinary project will 1) Impact various fields of research, such as structural and RNA biology 2) Has the potential for applications in human health due to the connections of the FASTK family to mitochondrial and inflammatory diseases, 3) Significantly develop the career of a talented researcher and 4) Contribute to the academic and research excellence at the University of Warsaw by establishing a new research group, introducing structural biology expertise, and bringing together local and international collaborations.;134462,4;134462,4;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;UNIWERSYTET WARSZAWSKI;PL;;;;1;0;0;1;0;0 195159;655703;Polyphemus;CLOSED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Towards a new framework for reception: Gongora’s poetics, ‘new’ readers and the material world;2015-05-01;2017-04-30;;"Luis de Góngora’s (1561-1627) two major compositions, Polifemo and Soledades (1613) represent a watershed in the trajectory of Spanish poetics; prompting a polemic over their stylistic innovations that would continue for three centuries. To date there has been suppression of the polemic’s politico-ideological underpinnings and undisputed acceptance that Góngora’s poetry was written to be read by an aristocratic, erudite elite. Consequently research on the reception of his work has been conceptually constrained and confined within the rigid parameters of documents relating to the controversy. The primary aim of this project is to challenge these fundamental assumptions of readership and reception and to propose a new methodological framework which has at its core a confluence of: (a) archival investigation; (b) analysis (qualitative and quantitative) of material evidence with digitalised data presentation; (c) a sophisticated theoretical underpinning that conceptualises literary reception within the wider tensions of socio-cultural self-constitution. The key sustaining hypothesis is that Góngora’s ‘new’ readers were not restricted to the intellectually-renovated receivers anticipated by the poet, but encompassed ‘other’ recipients drawn from a much broader socio-cultural spectrum (archival research carried out by the researcher informs this). Outputs include a journal article, a project website with open-access database, a book-length study and the organisation of an international conference. In line with MSCA objectives the project will enable a transfer of knowledge and interdisciplinary skills of mutual benefit to researcher and host; strengthen the contact networks of both, and enhance the career opportunities of the researcher through international exposure and inter-sectoral mobility. The project will promote collaboration between researchers, archivists and librarians, thus contributing to the recuperation of a significant aspect of Spain’s cultural heritage.-";195454,8;195454,8;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;THE QUEEN'S UNIVERSITY OF BELFAST;UK;;;;1;0;0;1;0;0 195010;654889;ITNUN;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Family, Power, Memory: Female Monasticism in Italy from 700 to 1100;2015-10-01;2017-09-30;;Recent history amply demonstrates the importance of religious belief as a fundamental historical force. In studying early medieval Europe, we see how crucial it has been in the creation of our own identity, underlying our belief systems, cultural assumptions and core values, as well as our institutions. Modern history and anthropology help us pose questions of immediate concern on ethnicity and nationality, women and gender, identity and belief. I have engaged with these issues previously, with a multidisciplinary mix of history, anthropology, art history and archaeology. This research project on Italian female monasteries from 700 to 1100 is also comparative and interdisciplinary. To understand medieval society, it is essential to understand monasticism, and crucial to include Italy. I propose to bring together an integrated and broad-sweeping perspective by joining these together, and to approach the study of religious women as a laboratory for exploring the complex relationship between gender and power. Royal or aristocratic monasteries have sources detailing the names, background and activities of nuns, representative of the political and ethnic composition of Italian society. To study the evolution of nunneries makes it possible to trace changes in Italian political, social and cultural patterns, with the intermingling of family and politics. Understanding the tensions between early medieval Italian society’s male-controlled political and religious power, and the influence of noble women as queens and nuns, is essential for grasping women’s ideological and spiritual power, and for recognizing the changing configurations of medieval Italy, a key factor for comprehending some issues still at stake in Italian society today. Generally, a study of key mechanisms concerning the relationship between women, religious belief and behaviour, and politics and society can, through comprehending these in the past, illuminate key aspects of modern European societies.;180277,2;180277,2;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;UNIVERSITA CA' FOSCARI VENEZIA;IT;;;;1;0;0;1;0;0 195384;657050;RES.CO.PART;CLOSED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Research Consultation and Participation:developing a tool for managing cultural heritage and landscape;2015-09-01;2017-08-31;;"This project aims to devise and implement a new tool for the sustainable management of cultural heritage. The RES.CO.PART tool will promote the efficient involvement of communities as stakeholders in decision-making processes for the management of cultural heritage in landscape. It will combine interdisciplinary methods of spatial analysis (especially Geographic Information System (GIS) based Historic Landscape Characterisation (HLC)) in a new way with research practices from cultural anthropology. The tool will help bridge the gap between theoretical appreciations of cultural heritage and the management practices that are actually applied on site. The tool will be developed through practical case-studies in two contrasting communities, Naxos in the Aegean Sea (Greece) and part of the East Devon ‘Area of Outstanding Natural Beauty’ (AONB) (UK). To implement this project, Dr Stelios Lekakis will move from Greece to Newcastle University in the UK, undertaking systematic training in GIS-related methodologies and especially the HLC tool, along with related skills in the visualisation of results for the public. The project results will be disseminated through a specifically designed open platform. To create this, he will also be trained in the process of building a digital, open-access tool for the collection and communication of relevant data by interested stakeholders.";183454,8;183454,8;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;UNIVERSITY OF NEWCASTLE UPON TYNE;UK;;;;1;0;0;1;0;0 195415;657240;ICONOPHILIA;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Religion, Politics and the Arts in Early Medieval Italy Against the Background of the ‘Image Struggle’ (680-850);2015-08-01;2017-07-31;;This project will specifically focus firstly on the development and dissemination of the theological matters that affected the policies of the Roman Catholic Church between the late seventh-mid ninth century, and secondly on the ‘translation’ of these theological matters into a literary and visual imagery. In the period 680-850 a great debate about the cult of sacred images – the Byzantine ‘image struggle’ or iconoclasm – engaged monks, emperors, popes. Sacred images have for different reasons ispired devotion or spurred iconoclastic reactions and cultural opposition world-wide and often in human history – unfortunately also in the last fifteen years. The place of sacred image in the actual Christian religious mentality – i.e. the way in which cult images stimulate reactions, are perceived, venerated, chosen as personal ‘talismans’ and intercessors with the divine in contemporary culture – was radically shaped by the intense period of the Byzantine ‘image struggle’. The political, cultural, and artistic interactions and the developments of Christian mentality between the West and the East during this phase are actually still a ‘grey area’ in Medieval and Byzantine studies, having been dealt with only occasionally and compartimentally. By using literary as well as visual evidence, 'ICONOPHILIA' will explore this ‘grey area’ and prove to be significant to a range of scholarly disciplines, while being appealing also to a wider global audience interested in religious mentality, Church history, history of monasticism, cultural policies, visual thinking, art production and consumption as socio-political statements. The Centre for Byzantine, Ottoman and Modern Greek Studies in Birmingham will provide the ideal intellectual environment for the development of this interdisciplinary project.;195454,8;195454,8;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;THE UNIVERSITY OF BIRMINGHAM;UK;;;;1;0;0;1;0;0 194485;647077;NewSpindleForce;SIGNED;H2020-EU.1.1.;ERC-CoG-2014;H2020;A new class of microtubules in the spindle exerting forces on kinetochores;2015-04-01;2020-03-31;;At the onset of division the cell forms a spindle, a micro-machine made of microtubules, which divide the chromosomes by pulling on kinetochores, protein complexes on the chromosome. The central question in the field is how accurate chromosome segregation results from the interactions between kinetochores, microtubules and the associated proteins. According to the current paradigm, the forces on kinetochores are produced by k-fibers, bundles of microtubules extending between the spindle pole and the kinetochore. The proposed project is built upon a groundbreaking hypothesis that a new class of microtubules, which we term bridging microtubules, bridge sister kinetochores. Our preliminary results show that bridging microtubules are responsible for the positioning of kinetochores in HeLa and PtK1 cells. Bridging microtubules have not been studied before because this requires cutting-edge microscopy and laser microsurgery techniques. By applying these methods, with which I have extensive expertise, we will determine the organization of these microtubules, identify the proteins that link them with k-fibers, and uncover where and how the forces for kinetochore positioning and movement are generated. My strength is in taking an interdisciplinary approach, which I will use in this project by combining laser microsurgery with genetic perturbations, quantitative measurements of the responses and comparison with theoretical models. Understanding the role of bridging microtubules in force generation and chromosome movements will not only shed light on the mechanism of chromosome segregation, but may also increase the potential of mitotic anticancer strategies, as the spindle is a major target for chemotherapy. The proposed ERC funding is essential for the success of these timely and ambitious experiments, allowing me to strengthen my position as an international leader in research on cell division, thereby increasing Europe's foremost position in this field.;2150000;2150000;ERC-2014-CoG;/ERC-COG;RUDER BOSKOVIC INSTITUTE;HR;;;;1;0;0;1;0;0 195496;657712;BETAPEV;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Beyond Empathy: Toward a phenomenological Ethics of Vulnerability;2015-04-01;2017-03-31;;According to a report, titled “Violence against Women: an EU-wide survey” and published by the European Union Agency for Fundamental Rights in March 2014, 'one in three women (33 %) has experienced physical and/or sexual violence since she was 15 years old, and, slightly more than half of all women in the EU (53 %) avoid certain situations or places, at least sometimes, for fear of being physically or sexually assaulted'. The report stresses that the “feeling of vulnerability” is prevalent among these women. Vulnerability is commonly defined as the “ability to be harmed”, and often associated with weakness or passivity. But the prevalence of the feeling of vulnerability among women in the European Union puts into question this framework and calls for a conceptual revaluation of this notion in order to address its ethical and social significance. This proposal aims to reconsider the moral and philosophical definition of vulnerability based on weakness and harm in order to elaborate a phenomenological ethics of vulnerability that goes beyond traditional accounts of empathy. To do so, the ontological framework of philosophical and psychological theories of empathy will be assessed. Political theories and development policies will be analyzed in order to offer solutions to prevent vulnerability from turning into violence and victimization. This proposal will rely on the phenomenological tradition to introduce the notion of “vulnerable bodily self” as a new paradigm to describe the individual. This research mixes theoretical analysis (phenomenology) and interdisciplinary empirical work (psychology, cognitive sciences, feminist theories). It bears significant consequences for contemporary philosophical discussions on the nature of the self. Its timeliness echoes a need for new theoretical paradigms to address political and social issues related to self-identity and people’s vulnerability in European societies.;173076;173076;H2020-MSCA-IF-2014;/MSCA-IF-EF-RI;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FR;;;;1;0;0;1;0;0 195512;657788;MEHYB;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Many-body effects in hybrid quantum systems;2015-04-01;2017-03-31;;"The interdisciplinary field of hybrid quantum systems pursues the integration of different quantum systems from AMO and solid-state physics to harness their combined functionalities in an optimal way. Prominent examples are long-lived spin ensemble quantum memories for superconducting qubits or (opto-)mechanical quantum transducers, which are currently experimentally implemented for future quantum information processing applications. The general aim of this project is to identify and analyze a new and range of applications for hybrid quantum systems for the study of non-equilibrium quantum many-body effects and phase transitions in open quantum systems. For that purpose the hybrid system approach offers many, still unexplored advantages for combining dissipative and coherent elements in a controllable and scalable way. The focus of this project is two-fold: i) We will analyze the implementation of collective spin models in hybrid quantum system arrays consisting of spin ensembles coupled to microwave cavities and show that this system can serve as prototype model for identifying universal features of non-equilibrium phase transitions in open quantum systems. ii) We will study superconducting qubit arrays with integrated nanomechanical resonators for the implementation of spin models coupled to engineered local reservoirs. This will provide a first realistic approach for simulating open many-body quantum systems coupled to unconventional reservoirs, exhibiting, for example, strong site-dependent temperature variations, or mixed positive and negative temperatures. Analyzing these specific models will open a path for hybrid quantum system arrays as a new quantum simulation platform for non-equilibrium and open quantum many-body systems.";166156,8;166156,8;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;TECHNISCHE UNIVERSITAET WIEN;AT;;;;1;0;0;1;0;0 195494;657701;LiVirIn;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;3D Liver Organoids: Modelling Host Hepatitis B Virus Interaction;2015-03-01;2017-02-28;;"An estimated ~400 million people are chronically infected with hepatitis B virus (HBV) infection worldwide, resulting in an estimated $658 million in medical costs and lost wages annually. Although HBV disease can be prevented by vaccination, many people still become infected. Potent and safe drugs are available to eradicate HBV viral particles and clinically ‘cure’ HBV infection. However, during replication HBV delivers a very stable form of viral DNA (covalently closed circular DNA, cccDNA) in the nucleus of the hepatocyte, causing life-long risk of reactivation of HBV infection in case of suppression of the immune system (e.g. chemotherapy). Therefore the pharmaceutical industry is now aiming to develop strategies to eradicate the virus from the infected liver completely. Such studies are hampered by the lack of appropriate in vitro or animal models due to the narrow tropism of HBV for human hepatocytes. The hypothesis of the project is that creation of 3D culture systems encompassing hepatocytes, hepatic stellate cells (HSCs) and liver sinusoidal endothelial cells (LSECs) derived from an inexhaustible source of cells (human pluripotent stem cells (PSCs)) in a matrix that mimics the biophysical and biochemical features of the liver, will be a superior model for the study of HBV infection and evaluation of the efficacy of antiviral drugs. We also hypothesize that such 3D organoids will improve maturation and function of hepatocytes, HSCs and LSECs. The proposed studies are highly interdisciplinary, merging expertise from biology, to biophysics and engineering, with inter-sector mobility, networking, collaboration and knowledge transfer between academia and industries. The knowledge developed will be disseminated by presentations at consortium meetings, international conferences and in peer publications. All these aspects will train the researcher as independent thinker, more knowledgeable in scientific research which will provide an enormous boost to his carrier.";172800;172800;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;KATHOLIEKE UNIVERSITEIT LEUVEN;BE;;;;1;0;0;1;0;0 195506;657755;ArtOxiZymes;CLOSED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Artificial Oxidation Enzymes for Highly Selective Waste Free Hydroxylation of Alkanes;2015-10-01;2017-09-30;;One of the major challenges facing the chemical industries is the sustainable production of chemicals from natural resources. The challenge includes making sure that chemical processes are as ‘green’ and economical as possible, and that sustainable and abundant resources are used where possible. One type of reaction that lends itself to sustainable processes is the direct functionalization of C-H to C-X (X = O, N, C) bonds, as it generates far less chemical waste and leads to tremendous reduction of energy use than methods relying on prefunctionalized materials. The objective of this project is to achieve the C1-selective hydroxylation of n-alkanes to give n-alcohols e.g. octane to octan-1-ol, using mild reaction conditions and green oxidants such as oxygen or hydrogen peroxide, which is currently an unsolved problem. Linear alcohols are of interest as they form some of the major building blocks used in the chemical industries, for example C8-C10 alcohols for the synthesis of plasticisers and detergents. We will achieve this aim by combining traditional homogenous catalysis and biocatalysis for the development of artificial metalloenzymes as catalysts, which utilise the molecular recognition concepts of nature to bind substrates selectively in protein pockets. The target substrate will thus be bound in the correct orientation enabling selective oxidation at the target position, in contrast to traditional chemocatalysts which give a highly unfavourable product distribution. This will lead to more efficient use of valuable feedstocks and large reductions in chemical waste production and energy consumption, compared to the traditional methods for forming C1-alcohols, all contributing to a green and sustainable society. The researcher will diversify her competence, build new collaborations and gain interdisciplinary mobility through this creative and highly innovative project allowing her to maximise her contribution to the knowledge-based economy and society.;183454,8;183454,8;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;THE UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS;UK;;;;1;0;0;1;0;0 196136;661645;IDEA;CLOSED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Investigating Dishonesty with Experimental Applications: Evidence from the Lab and the Field;2015-06-01;2017-05-31;;Trust plays a very important role in economic and social interactions. It reduces transaction costs, promotes efficiency in markets, improves cooperation, and increases the ability of people, organizations and countries to adapt to complexity and change. Trust is also very fragile and can be easily break with extremely detrimental consequences for society. This highly interdisciplinary research project aims to develop a pioneer analysis of what is considered one of the most fundamental threats of trust, and, a major concern of modern society: dishonesty. The central objective of “IDEA” is to provide a better understanding of the determinants of dishonest behaviour by incorporates psychological, emotional and social factors that have been only recently brought into economics. Within this framework, “IDEA” intends to develop and test new mechanisms to fight against dishonesty which entail a lower cost for society, and preserve the freedom of citizen. More specifically, “IDEA” will investigate what individual characteristics are more/less likely to be associated with dishonest behaviour to provide a better understanding of deceptive behaviour, and obtain an identikit of a dishonest individual. It will examine the nexus between dishonesty and competition, in order to determine why competitive pressures induce more cheating, and which features of the competitive environment are linked to more dishonesty. By exploring the deterrence effect of information disclosure on audits and sanctions, “IDEA” will help to develop an optimal system of sanctions which discourage dishonesty, and minimize the monetary costs of the enforcement authority and the psychological costs of the citizens.;185076;185076;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;UNIVERSITE LYON 1 CLAUDE BERNARD;FR;;;;1;0;0;1;0;0 196125;661583;CONSCBRAIN;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;How consciousness is shaped by neuronal network dynamics;2015-05-01;2017-04-30;;How does the structure of the brain give rise to its function? We will address this longstanding neuroscience question through an interdisciplinary research project, by using computational modelling to study the neuronal dynamics which underlies the specific brain function of consciousness. More precisely we propose to investigate the differences in neuronal dynamics between conscious and unconscious brain states, and how conscious experience is shared across subjects watching a movie. The project capitalizes on using whole brain models that are constrained by anatomical and functional connectivity data from humans and non-human primates. In a first study, we will test whether differentiation of brain activity, as indicated by homogeneity differences of functional connectivity patterns across the modelled brain areas, can serve as a marker of consciousness. In a second study we will construct a whole brain model of experiments in which subjects synchronize their brain activity when watching a natural stimulus such as a movie. Through external stimulation of the model we will determine the set of brain areas that is causally involved in driving this synchronization of conscious experience. The results will give new theoretical insights on how neuronal interactions at an entire brain’s scale are informative of consciousness and shared conscious experience across subjects.;170121,6;170121,6;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;UNIVERSIDAD POMPEU FABRA;ES;;;;1;0;0;1;0;0 196037;661035;KaMCAM;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Kac-Moody groups and Computer Assistants in Mathematics;2015-08-01;2017-07-31;;"This fellowship will enable the experienced Researcher Dr Rieuwert Blok - a currently USA-based European Union national - and Dr Corneliu Hoffman - as Host researcher based at the University of Birmingham - to carry out innovative and mutually beneficial research utilising their complementary skill sets. Blok brings extensive research experience in buildings, Lie theory and geometries while Hoffman's background is in group theory, representation theory and number theory. The fellowship aims to create optimal conditions for the Researcher to reintegrate into ERA for the benefit of both the Researcher and the ERA. The action comprises two distinct, yet interconnected Work Packages. The first one concerns Curtis-Tits groups, a large family of groups recently introduced by the Researcher and Dr Hoffman. This family includes groups of established importance, namely groups of Lie and Kac-Moody type, but in fact contains many new groups of great theoretical significance and practical interest. The action develops methods that open up this promising family for further study. It then determines key properties such as simplicity, and explores and establishes applications in geometric group theory, combinatorics, group presentations, and computer science. The subject area is an innovative blend of group theory, homological algebra, topology, geometry, number theory and computer science. The second package is an interdisciplinary project between mathematics and computer science, exploring the promise of effectively using the recent developments surrounding proof assistants in teaching and research. It builds forth upon pioneering work in this direction by both researchers at their respective universities.";195454,8;195454,8;H2020-MSCA-IF-2014;/MSCA-IF-EF-RI;THE UNIVERSITY OF BIRMINGHAM;UK;;;;1;0;0;1;0;0 196981;665667;EPFL Fellows;SIGNED;H2020-EU.1.3.4.;MSCA-COFUND-2014-FP;H2020;Experienced Researchers Incoming Fellowship Programme at the Ecole Polytechnique Fédérale de Lausanne;2015-07-01;2020-06-30;;"EPFL Fellows aims to attract experienced researchers of any nationality to EPFL - one of the leading European institutions of science and technology - to provide them with state-of-the art conditions for research in a top-class academic environment, to develop their leadership potential and to position them for success as future research leaders through an intensive training. EPFL Fellows is a relatively new programme; it started in 2013 with the support of the EU MCA-COFUND (FP7). Fellowships may be requested in any scientific discipline and run for a period of 24 months. In the context of this new COFUND proposal several new elements are introduced in EPFL Fellows to fine-tune the programme and align it with the principles set out by the EU for human resources development in Research and Innovation: i) the number of fellowships to be awarded is increased from 24 to 48; an appropriate increase in view of demand, of what EPFL can offer, and of the high selectivity of fellowships currently awarded, ii) fellows are asked to show elements of interdisciplinarity and cross-sectorial mobility in their research projects and are encouraged to carry out secondments in industry or different scientific environments, iii) employment conditions are improved by giving fellows access to Dual Career measures, iv) fellows are expected to actively participate in outreach activities, v) tangible measures are offered to facilitate transfer of technology to the market place through access to EPFL’s Tech Transfer Office and Innovation Square, vi) adaptations are made in the selection procedure to align it with the MSCA IF process and to externalize the evaluation of the proposals to the fullest extent possible while ensuring that the final decision-making process is managed in-house and hence under control. This proposal will take the “EPFL Fellows” postdoctoral fellowship programme to its next level, and open the doors of EPFL and Europe to two new cohorts of 24 promising scientists.";6796800;3398400;H2020-MSCA-COFUND-2014;/MSCA-COFUND-FP;ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE;CH;;;;1;0;0;1;0;0 204991;722937;EVERYDAYNIGHT;CLOSED;H2020-EU.1.3.5.;MSCA-NIGHT-2016;H2020;Wielkopolska Researchers’ Night welcomes - Let the experience of the Night last every day!;2016-05-01;2017-11-30;;"'Researchers’ Night again in Poznan! EVERYDAYNIGHT! Wielkopolska Researchers’ Night welcomes - Let the experience of the Night last every day! Come and see how research influences your every-day life! Reveal the interdisciplinary nature of science and learn how different scientific fields complement each other, making our life better. Join speed dating with our researchers, defeat them in quizzes and win a badge of the young scientist! See how future school will look like, reveal how environment interacts with robotics and sport. Meet MC fellows and convince yourself that career in science is a great adventure! Feel the atmosphere of NASA laboratory. Take part in “Mamma Mia” show - sing and dance with researchers, meet exoskeletons and discover the economics of joking. Feel like doing some sport? Come and play fitball, tennis or basketball with researchers. These and many other attractions are waiting for you to reveal your passion for science and convince you that researchers are just ordinary people with an extraordinary job and various hobbies. EVERYDAYNIGHT is a continuation of the Researchers’ Night projects of the past nine years, which were highly successful gathering in 2015 app. 59 000 participants. The project builds on last years’ experiences and aims at strengthening efforts to bringing researchers closer to the public at large, increase the awareness of research, by supporting the public recognition of researchers, clearly showing the impact of researchers’ work on society and every-day life. Activities during the Night on 30 September 2016 and 29 September 2017 will focus on public at large and will have hassle-free and festive character, being a valid alternative to 'traditional Friday night activities'. Those activities will offer a direct contact between researchers and public, combine fun elements (edutainment), envisage linking together Nights organised in different cities in Poland and ensure active involvement of both researchers and audience. '";140347,5;133347,5;H2020-MSCA-NIGHT-2016;/CSA;POLITECHNIKA POZNANSKA;PL;"UNIWERSYTET IM. ADAMA MICKIEWICZA W POZNANIU;UNIWERSYTET PRZYRODNICZY W POZNANIU*;INSTYTUT CHEMII BIOORGANICZNEJ POLSKIEJ AKADEMII NAUK;AKADEMIA WYCHOWANIA FIZYCZNEGO IM EUGENIUSZA PIASECKIEGO;UNIWERSYTET EKONOMICZNY W POZNANIU";PL;;1;0;0;1;0;0 203488;705499;HArchitHeC;TERMINATED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;House Architecture and Heritage in modern Crete;2016-06-01;2018-05-31;;"Cretan minor built heritage dating back to the Venetian and Ottoman periods has until now received scarce attention by scholars and local authorities. The two-year HArchitHeC project (House Architecture and Heritage in modern Crete) wants to focuses on rural and urban houses of Crete in order to reach three main goals: to perceive the built environment in its materiality and its historical evolution; to study how the evolution and interaction of Venetian and Ottoman cultural models built up a hybrid architecture in a colonial dimension; and to identify possible strategies for heritage protection by bringing research to the public realm. To do so, an interdisciplinary innovative approach will be used: a historical study of written sources and an architectural comparative study, by means of an inventory and a comparative study of Venetian and Turkish house prototypes. Such a pilot project aspires to a wider comparative study between Crete and the nearby regions, starting with other Mediterranean islands (Rhodes and Cyprus at first). HArchitHeC represents the first occasion to put into effect a mutual commitment between the two institutions that is the IMS (Greece) as the Host and Aix-Marseille University (France) as the Partner. They will provide an ideal human and scientific environment for the fellow, supporting her research and career development. The fellow’s previous achievements in terms of fieldwork and research, as well as her knowledge of Cretan territory and academic staff will allow her increasing methodologies and results. She will reinforce her competences and acquire new skills: her ultimate goal is to be fully integrated in the fields of cultural history and architectural heritage, acting on European society and science. HArchitHeC shows its relevance to the work programme, since it foresees a complete plan of training-through-research, as well as specific outreach and communication activities to reach a wide audience beyond academics.";164653,2;164653,2;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS;EL;;;;1;0;0;1;0;0 201352;705633;SYNC;TERMINATED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Synchronizing Palaeoclimate data for better understanding of the Solar effect on European Climate;2016-09-01;2018-08-31;;The sun activity is decreasing since 1996 and a grand solar minimum is expected to occur from 2020 to 2070. The magnitude of solar forcing on the current climate is still uncertain. This project aims to test the existence of quasic-periodic decadal to centennial natural climate variability modulated by grand solar minima during the Late Holocene, which resulted in abrupt climate changes in Europe on time-scale of a few years and has the potential to trigger comparable changes in the future. Describing the timing and the abruptness of the climate response to shifts in the solar activity requires very accurate climate reconstructions and dating, in particular where absolute ages are hampered by the presence of 14C plateaux. This research project will focus on the precise comparison of Late Holocene palaeoclimate records from annually resolved (varved) archives across Europe, with the core goal of estimating the velocity of the climate response to grand solar minima and possible seasonal effects. The project’s novelty lies in the synchronization of very accurate varve chronologies from two European lakes, Diss Mere (England) and Meerfelder Maar (Germany), using tephra layers as synchronous markers. Tephrochronology and varve counting will thus be integrated as a multidisciplinary dating method to minimize the uncertainty derived from individual chronologies (varve counting error). Tephra (volcanic ash) from explosive eruption and atmospheric cosmogenic isotopes s are deposited over large areas synchronously and are reliably correlated to known eruptions. Varved sediments provide accurate chronologies and also store climatic signals at seasonal resolution. The interdisciplinary perspective adopted by this study is designed to tackle gaps in our knowledge of the solar-climate phasing and to provide the most precise proxy data to the climate modelling community. The facilities of Royal Holloway, University of London supports the innovate methodological approach.;195454,8;195454,8;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;ROYAL HOLLOWAY AND BEDFORD NEW COLLEGE;UK;;;;1;0;0;1;0;0 195720;659104;LeSoDyMAS;TERMINATED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Learning in the Space of Dynamical Models of Adrenal Steroidogenesis “LeSoDyMAS”;2015-07-13;2017-07-12;;"To date most successful machine learning techniques for the analysis of complex interdisciplinary data predominantly use significant amounts of vectorial measurements as input to a statistical system. The domain expert knowledge is often only used in data preprocessing and the subsequently trained technique appears as a black-box, which is difficult to interpret or judge and rarely allows insight into the underlying natural process. However, in many bio-medical applications the underlying biological process is complex and the amount of measurements is limited due to the costs and inconvenience for the patient. The main aim of this project is the formulation of a generalised framework for learning in the space of probabilistic models representing the complicated underlying natural processes with potentially very few measurements. This includes the development of a similarity measure for posterior distributions, task-driven model simplification and a new learning paradigm to combine those modules. The method will be developed for the prediction of steroid flow in the treatment of Congenital Adrenal Hyperplasia (CAH) incorporating dynamical models of Adrenal Steroidogenesis. With the successful execution of this project we expect not only better prediction performance for individual treatment success, but also deeper understanding of the pathophysiologic processes due to the incorporation of the pathway models. The project combines the expertise of the Fellow (Dr. Bunte) in task-driven similarity learning and dimensionality reduction with the expertise of the Host Coordinator (Prof. Tino, The University of Birmingham (UoB)) in probabilistic modelling, dynamical systems and model-based learning. The UoB and all participants (University of Sheffield,Warwick and the company Diurnal Ltd) provide further bio-medical and modelling expertise, and have already successfully collaborated in previous projects, including the clinical data targeted in this proposal.";183454,8;183454,8;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;THE UNIVERSITY OF BIRMINGHAM;UK;;;;1;0;0;1;0;0 195668;658806;LUMIMAGNET-NANO;TERMINATED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Multifunctional luminescent and magnetic nanoparticles for advanced biomedical applications;2015-05-18;2017-05-17;;"The key goals of the “LUMIMAGNET-NANO” project are: (a) the training of a talented young researcher, Dr. Rosa Martín-Rodríguez, in the fast growing field of science, technology and industrial applications of nanomedicine, where the host and partner institutions have a critical knowledge and expertise; and, (b) the design, development and optimisation of cost-efficient magnetic nanoparticles with multifunctional recovering for biomedical applications. The aim of the research project is to take advantage of both magnetic and optical properties for magnetic hyperthermia applications. The interdisciplinary training program includes preparation of magnetic nanomaterials, surface modification to provide luminescent functionality, characterization, spectroscopic studies including X-ray absorption spectroscopy in synchrotron radiation facilities, in-vitro study, and implementation for hyperthermia applications. The fellow is a talented researcher who has gained much expertise in synthesis and structural and spectroscopic characterization of luminescent nanomaterials and cell biology protocols during her undergraduate and postgraduate career. To further boost her career, she needs to gain expertise in preparation of biocompatible nanoparticles, magnetic characterization techniques, X-ray absorption spectroscopy and hyperthermia applications, fields in which the University of Basque Country has a world-recognised expertise. Additionally, through two three-month secondments at academic and industrial co-hosts, University of Rome Tre and Resonant Circuits Ltd. respectively, the fellow will gain additional high-level training in X-ray spectroscopy and industrial hyperthermia applications. This multidisciplinary project will also increase her supervision experience, project and intellectual property management expertise, and research funding and proposal writing skills.";170121,6;170121,6;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA;ES;;;;1;0;0;1;0;0 194619;649773;MEnS;SIGNED;H2020-EU.3.3.7.;EE-04-2014;H2020;Meeting of Energy Professional Skills;2015-03-01;2017-08-31;;"MENS is a project conceived in order to provide an enhance the NZEB skills of building managers such as engineers and architect through a series of accredited training activities developed by 9 universities and 3 market players. MENS aims: - To increase the knowledre and skills of at least 1800 building managers (engineers, architects) in NZEB design and construction, out of which 50% would be women or unemployed. - To create and implement a new education and training program for such professionals in 10 countries, under the European Qualifications Framework provisions and based on desired and common learning outcomes of Level 7. - To create and implement an innovative, interdisciplinary education and training program with an integrated approach, focusing on real case studies - To accredit courses using the formal procedure in each country and assign ECTS credits. - To enhance and support the development of a professional network in Europe specifically focused on retrofitting of housing stocks towards NZEB. A connection with over 250,000 stakeholders and market players. - To provide working opportunities to unemployed professionals, by bringing them closer to possible employers and improving their qualifications, at a percentage of 30% of those attending. - To continue the education and training courses for at least 5 years after the end of the project based on concrete sustainability plans agreed by University partners. - To result in energy savings and/or increased use of renewables of at least 28,96 GWh/year. MENS is developed through 3 sets of training activities: national accreditation professional courses; e- learning and webinars: and case studies experiences around Europe and it involves involves major universities and stakeholders either directly or as Associated Partners engaged with LOS. MENS finally benefits from a strong media promotional activity through a wide network of local TVs and RTBF.";1478160;1478160;H2020-EE-2014-3-MarketUptake;/CSA;ENERGIA-DA SRL;IT;"INSTITIUID TEICNEOLAIOCHTA BHAILE ATHA CLIATH;ARISTOTELIO PANEPISTIMIO THESSALONIKIS;UNIVERSITATEA TEHNICA CLUJ-NAPOCA;KNOWLEDGE TRANSFER NETWORK LIMITED;UNIVERSITE LIBRE DE BRUXELLES;ENERGY CONSULTING NETWORK APS;UNIVERSITAET KASSEL;RADIO-TELEVISION BELGE DE LA COMMUNAUTE FRANCAISE;BRUNEL UNIVERSITY LONDON;UNIVERSITAT POLITECNICA DE VALENCIA;UNIVERSITY OF CYPRUS;Ss. CYRIL AND METHODIUS UNIVERSITY IN SKOPJE";"IE;EL;RO;UK;BE;DK;DE;ES;CY;MK";;1;0;0;1;0;0 194513;647573;MODEST;SIGNED;H2020-EU.1.1.;ERC-CoG-2014;H2020;Mathematical Optimization for clinical DEcision Support and Training;2015-07-01;2020-06-30;;"Physicians need to make many important decisions per day. One clinical example is the scheduling and dosage of chemotherapy treatments. A second example is the discrimination of atrial fibrillation from atypical atrial flutter, based on ECG data. Such important and complex decisions are usually based on expert knowledge, accumulated throughout the life of a physician and shaped by subjective (and sometimes unconscious) experience. It is not readily transferable and may be unavailable in rural areas. At the same time, the available imaging, laboratory, and basic clinical data is abundant and waits to be used. This data is not yet systematically integrated and often single data-points are used to make therapy decisions. More and more clinical decision making tasks will be modeled in terms of mathematical relations. I propose a systematic approach that supports and trains individual decision making. The developed ideas, mathematical models, and optimization algorithms will be generic and widely applicable in medicine and beyond, but also exploit specific structures, resulting in a patient- and circumstance-specific personalized medicine. This allows, e.g., a physician to first simulate the impact of his decisions on a computer and to consider optimized solutions. In the future, it will be the rare and unwanted exception that an important decision can not be backed up by consultation of a model-driven decision support system or based upon a systematic model-driven training. MODEST has a mathematical core. It builds on a comprehensive, interdisciplinary work program, based on disciplinary expertise in mixed-integer optimal control and existing collaborations with medical and educational experts. It is both timely, given the increasing availability of data and the maturity of mathematical methods, models, and software; as well as high-impact, due to the large number of clinical areas that may benefit from optimization-based decision support and training tools.";1998500;1998500;ERC-2014-CoG;/ERC-COG;OTTO-VON-GUERICKE-UNIVERSITAET MAGDEBURG;DE;;;;1;0;0;1;0;0 195012;654911;THALAMODEL;TERMINATED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Multimodal, high-resolution modeling of the thalamus for neuroimaging studies: application to dyslexia;2015-06-01;2017-05-31;;"The thalamus is a brain structure that is responsible for important functions (e.g., sensory systems, sleep, the motor system, spoken language) which are distributed over its 12 nuclei . While recent advances in MRI technology have made it possible to image the thalamic nuclei in vivo, the lack of specific computational tools to analyze the images forces most research studies to either treat the thalamus as a single structure (limiting the spatial specificity of the analysis) or to rely on the excruciating process of manually labeling the data. Since very few sites currently possess the anatomical expertise and staffing resources to carry out studies based on manual delineations, the lack of tools to analyze MRI data of the thalamus is hampering progress in different branches of neuroscience. Here we present an interdisciplinary project to build tools to automatically analyze the thalamic nuclei in MRI data. The tools will be based on a statistical atlas of the thalamus built upon ultra-high resolution MRI and histological data from autopsy samples. We will use the tools in a study of the relation between thalamus and dyslexia, where they promise to increase our understanding of the pathology by testing which nuclei are affected and to what extent. In addition, the tools will be distributed as part of the software package FreeSurfer, allowing its over 10,000 worldwide users to carry out cognitive neuroscience experiments at the nucleus level, and to discover new imaging biomarkers of other diseases related to the thalamus, e.g. Alzheimer's, Parkinson's, MS and ALS. This project will allow the host to acquire knowledge in medical image analysis from the applicant and to establish collaborations with Harvard and Oxford (host of the proposed secondment). The project will also expand the applicant’s research network and train him in areas (ex vivo MRI, psycholinguistic studies) that complement his image analysis skills, preparing him for a future faculty position.";170121,6;170121,6;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;BCBL BASQUE CENTER ON COGNITION BRAIN AND LANGUAGE;ES;;;;1;0;0;1;0;0 195999;660783;TERA-NANO;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Beam steering, frequency reconfigurable terahertz photomixer array using nano-actuators;2015-04-01;2017-03-31;;"The research on terahertz technology has become one of the emerging fields due to the unique properties that it offers, presenting enabling alternatives in imaging, spectroscopy, and communication applications. Increasing research activities in the field also brings the need for high performance components that operate in the terahertz regime, the most important of which are the high performance sources and detectors. Photomixing is one of the most commonly used methods for terahertz generation and detection, which employs an ultrafast semiconductor substrate integrated with an antenna. The state-of-the-art photomixer antennas have either a low radiation resistance in a wide band or a high radiation resistance in a narrow band, both of which introduce a significant reduction in the amount of terahertz power generated or detected. Possible antenna reconfigurability options to overcome these issues have not been investigated so far due to the lack of high performance switching elements in the terahertz band, which could boost the antenna, and hence, photomixer performance significantly. Moreover, electronically controlled beam steering possibilities, which could enhance the system performance radically in terahertz imaging and communication applications, have not been studied to date, which also requires high performance switching elements. In this project, we aim to develop, for the first time, beam steerable and frequency reconfigurable photomixer antenna array for terahertz generation and detection. Beam steering and frequency reconfiguration will be achieved by means of nano-actuators, which is expected to provide high performance switching at terahertz frequencies. The nano-actuators that we target to develop will be the smallest ones reported up to date, which is mandatory to integrate them into the very small antenna dimensions. The proposed project will be a high level of interdisciplinary research between optics, electronics, and mechanical engineering.";157845,6;157845,6;H2020-MSCA-IF-2014;/MSCA-IF-EF-RI;ANKARA YILDIRIM BEYAZIT UNIVERSITESI;TR;;;;1;0;0;1;0;0 196080;661323;CarboPlex;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Development of carbon-rich biochar-mineral complexes for soil amendment, carbon sequestration and beyond (CarboPlex);2015-04-01;2017-03-31;;Aim of this project is to investigate and exploit the potentials of a new material termed biochar-mineral complex (BMC). The simple yet ground-breaking idea is to use common waste streams to produce BMCs with distinct properties. Primary target is the use of BMCs as soil amender, especially in soils, where the delicate but crucial structure of organo-mineral complexes is threatened by unsustainable soil use or climate change. Where pure biochar is known to face its limits, BMC because of its mineral part is assumed to enable much higher functionality (i.e. water and nutrient storage). To provide evidence-based information on production, properties and soil effects of BMC, a systematic study will be conducted. The highly interdisciplinary work is split into five strongly interconnected work packages, which cover the whole BMC lifespan from production to soil use and technology assessment. Most of the work will be conducted at the University of Edinburgh (UoE). A secondment is planned at Enrich Environmental Ltd., an innovative Irish waste treatment SME, where the potentials and requirements for successful large-scale implementation will be investigated. Introducing this original work to the scientific communities (i.e. waste, agriculture, soil, material science) is expected to make enormous impact. Strong attention is also paid to dissemination of the results to the industry, other stakeholders and the general public. The ER, in addition to the expected excellent research, profits greatly from new experiences with pyrolysis (UKBRC) and business management (Enrich) supporting his strive for an academic career as professor. The UoE benefits from the ER’s experiences in hydrothermal carbonization and gaining competence in BMCs. Enrich, in return, has strong interest to expand its range of products and to integrate innovative processes such as BMC production. Naturally, the ER, UoE and Enrich are strongly committed to the planed action and a most successful outcome.;183454,8;183454,8;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;THE UNIVERSITY OF EDINBURGH;UK;;;;1;0;0;1;0;0 196046;661068;INDLINK;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Growth and Diversification in the Presence of Industry Linkages;2015-04-01;2017-03-31;;"This project investigates the growth and diversification patterns of countries in the presence of industry linkages in four separate but complementary objectives. In the f?rst objective, the consequences of the linkages will be captured through the observed pattern of industries throughout countries and an economic micro-foundation will be provided using trade models. In the second objective, the diversification pattern and speed of countries will be related to the country level and product level quality measures. In the third one, temporal aspect of the trade data will be used and the effects of the spillovers will be analyzed using vector autoregressive models. Finally, in the fourth objective, effects of one specific type of spillover, namely the Input-Output linkages, will be explored both theoretically and empirically. The Experienced Researcher intends to build a successful academic career and impacting the decisions of policymakers within Turkey and Europe. This fellowship will enable Dr. Yildirim to embark on such a journey in a suitable environment provided by Koç University. The fellowship will complement Dr. Yildirim’s interdisciplinary background and he will also have the opportunity to establish himself in the field of economics.";157845,6;157845,6;H2020-MSCA-IF-2014;/MSCA-IF-EF-RI;KOC UNIVERSITY;TR;;;;1;0;0;1;0;0 195831;659671;ENGAGE;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Encouraging Network Generation’s Accountability and Global Engagement;2015-09-01;2016-08-31;;"The key aim of ENGAGE is to address young people's participation in society via social media. ENGAGE focuses on understanding new forms of political and civic engagement within the digital visual cultures and social networked societies that young people from Norway and the United Kingdom are a part of. Through a comparative study focusing on two cities, Sheffield and Oslo, the project will explore how social, cultural and political events are experienced and expressed through images by young people in everyday contexts of digital socialization. To address these aims the project will draw on feminist media approaches, photo theory and debates within post-structural theory and philosophy. It will advance an innovative methodological approach, using digital ethnographic methods in alignment with network analyses and computational Big Data methods and techniques. In order to encourage young people to become responsible citizens and actively engage in civic and political society, we need more insight into the recent explosive growth in image sharing, giving rise to an emergent visual digital media public. With an interdisciplinary approach, triangulating small- and big-scale social media image data, theory and methods; this project has the potential to significantly contribute to our understanding of this emergent visual digital media public in Europe. The Information School, at the University of Sheffield will host the Individual Fellowship. Specifically it will be located within the Visual Social Media Lab (VSML), led by Dr.Vis, who will supervise the project. The Fellowship will also be in close collaboration with The Sir Bernard Crick Centre for the Public Understanding of Politics (SBCC) . The Individual Fellowship has the potential to offer excellent impact for Dr.Pr?itz' career: it is a significant and exciting opportunity to acquire and transfer knowledge, and offers the potential for long-term collaboration between the iSchool, Dr Vis, VSML, SBCC and Pr?itz.";97727,4;97727,4;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;THE UNIVERSITY OF SHEFFIELD;UK;;;;1;0;0;1;0;0 197486;640553;ACTOMYO;SIGNED;H2020-EU.1.1.;ERC-StG-2014;H2020;Mechanisms of actomyosin-based contractility during cytokinesis;2015-07-01;2020-06-30;;"Cytokinesis completes cell division by partitioning the contents of the mother cell to the two daughter cells. This process is accomplished through the assembly and constriction of a contractile ring, a complex actomyosin network that remains poorly understood on the molecular level. Research in cytokinesis has overwhelmingly focused on signaling mechanisms that dictate when and where the contractile ring is assembled. By contrast, the research I propose here addresses fundamental questions about the structural and functional properties of the contractile ring itself. We will use the nematode C. elegans to exploit the power of quantitative live imaging assays in an experimentally tractable metazoan organism. The early C. elegans embryo is uniquely suited to the study of the contractile ring, as cells dividing perpendicularly to the imaging plane provide a full end-on view of the contractile ring throughout constriction. This greatly facilitates accurate measurements of constriction kinetics, ring width and thickness, and levels as well as dynamics of fluorescently-tagged contractile ring components. Combining image-based assays with powerful molecular replacement technology for structure-function studies, we will 1) determine the contribution of branched and non-branched actin filament populations to contractile ring formation; 2) explore its ultra-structural organization in collaboration with a world expert in electron microcopy; 3) investigate how the contractile ring network is dynamically remodeled during constriction with the help of a novel laser microsurgery assay that has uncovered a remarkably robust ring repair mechanism; and 4) use a targeted RNAi screen and phenotype profiling to identify new components of actomyosin contractile networks. The results from this interdisciplinary project will significantly enhance our mechanistic understanding of cytokinesis and other cellular processes that involve actomyosin-based contractility.";1499988,75;1499988,75;ERC-2014-STG;/ERC-STG;INSTITUTO DE BIOLOGIA MOLECULAR E CELULAR-IBMC;PT;;;;1;0;0;1;0;0 197869;648319;HyMAP;SIGNED;H2020-EU.1.1.;ERC-CoG-2014;H2020;Hybrid Materials for Artificial Photosynthesis;2015-07-01;2020-06-30;;"HyMAP aims to develop a new generation of multifunctional hybrid photocatalysts and solar photoreactor which would allow the exploitation of at least the 1 % of the sunlight energy for the CO2 photoreduction using water as electron donor. This will imply a CO2 conversion in the range of 12 to 35 Ton/y•ha, depending on product distribution, which represents at least a 20-fold improvement over the state of the art. To achieve this goal, I propose an interdisciplinary research program through which several breakthroughs at different scales will be achieved: Development of efficient multifunctional organic/inorganic semiconductors and metal-organic frameworks photocatalysts with separated reduction/oxidation active sites. The fact of having independent multiple redox sites combined in a single material would maximize charge separation and transport processes, as well as sunlight harvesting. Characterization and modelling of the structural and opto-electronic properties of the proposed materials. Evaluation of the materials in artificial photosynthesis devices. At this stage, a solar photoreactor that would allow good transmission, uniform light distribution and maximize the energy harvesting in the overall spectra will be developed. HYMAP will provide me with an excellent opportunity to lead a consolidated research group. During my scientific career I have demonstrated creative thinking, autonomy and an excellent capacity to carry out state of the art research in heterogeneous catalysis, characterization, modelling and reactor engineering. I have a meritorious research track reflected by a good number of scientific publications, broad professional expertise, innovative project conception and a consolidate network of international collaboration. This, along with my leadership and management abilities, will assure the successful achievement of the mentioned goals of this project. HyMAP is a revised version of a proposal scored with A (2nd stage) of last ERC-CoG call.";2506738;2506738;ERC-2014-CoG;/ERC-COG;Fundacion IMDEA Energia;ES;;;;1;0;0;1;0;0 194581;649439;FairTax;SIGNED;H2020-EU.3.6.;EURO-1-2014;H2020;Revisioning the ‘Fiscal EU’: Fair, Sustainable, and Coordinated Tax and Social Policies;2015-03-01;2019-02-28;;"Plans for economic and monetary integration in the European Union call for fundamental changes in fiscal relations among EU member states and other countries. The 2012 Blueprint for the European Monetary Union (EMU) calls for deeper integration of fiscal policies at the level of domestic EU members, including establishing EU own-source revenues. The 2013 Social Dimension of the EMU emphasizes that this fiscal revisioning must also improve coordination of employment and social policies post-crisis to counteract declines in state revenues, evaluate fragmented policy initiatives during the crisis, and improve human well-being and capabilities ends in themselves and as preconditions to stable integration and sustainable growth. This project will carry out in-depth comparative, interdisciplinary research using constitutional, legal, technical, institutional, qualitative, and quantitative methods to address four core issues: * Options for expanding EU legislative competences or governance mechanisms for effective harmonization of member tax and social policies; * Reform options for state-level coordination of fairer, more stable, and more sustainable tax and social policy regimes; * Strategies for the increased effectiveness and harmonization of tax administration and compliance structures within the EU and non-EU areas; and * Recommendations for true own-source EU revenues. This project is relevant to fundamental political and structural challenges that face the EU as it pursues deep fiscal integration. Fiscal policies encompass both revenue production and state spending priorities, and have tremendous impact on life choices, business planning, and economic development. Whether under conditions of stable growth or disruption, state revenues remain at the heart of state governance capacities; throughout, the well-being of the population as a whole remains at the heart of social and political stability and productivity.";2889000;2472750;H2020-EURO-SOCIETY-2014;/RIA;UMEA UNIVERSITET;SE;"FUNDACAO GETULIO VARGAS;THE UNIVERSITY OF EXETER;LINKOPINGS UNIVERSITET;NATIONAL UNIVERSITY OF IRELAND GALWAY;STIFTELSEN HANDELSHOYSKOLEN BI;COPENHAGEN BUSINESS SCHOOL;Queen's University at Kingston;OSTERREICHISCHES INSTITUT FUR WIRTSCHAFTSFORSCHUNG VEREIN;KING'S COLLEGE LONDON;MENDELOVA UNIVERZITA V BRNE";"BR;UK;SE;IE;NO;DK;CA;AT;CZ";;1;0;0;1;0;0 208286;714472;Mitomorphosis;SIGNED;H2020-EU.1.1.;ERC-2016-STG;H2020;Metabolic regulation of mitochondrial morphology;2017-04-01;2022-03-31;;The need for mitochondria in the body is ubiquitous yet the shapes these organelles take vary widely across tissues and change rapidly in response to nutrient availability. How and why this occurs is not well understood. Therefore, we propose an interdisciplinary research program that will investigate the molecular basis and metabolic regulation of mitochondrial morphology. Mitochondrial morphology is defined by opposing events of fission and fusion, which must be tightly controlled. We discovered that accelerated mitochondrial fission impairs cardiac metabolism and causes heart failure in mice, revealing an intriguing link between mitochondrial dynamics and metabolism. Seeking to understand how metabolic signals drive mitochondrial fission, we will characterize the inner membrane protein MTP18, whose fission activity is controlled by the PI3K nutrient-signalling pathway. First, we will define the interactome of MTP18 to discover the molecular components of the inner membrane fission machinery. Second, we will investigate the how mitochondrial fission is regulated by PI3K nutrient-signalling pathway the heart, liver, and kidney. We will determine whether cardiac dysfunction, liver cancer, and kidney failure caused by over-active PI3K signalling in the mouse can be rescued by blunting the downstream activity of MTP18 and re-balancing mitochondrial dynamics. Third, we will determine the disease relevance of mitochondrial fission in humans. For the first time, mitochondrial morphology from patient-derived cells will be evaluated in automated, high content screens to identify human mutations that drive imbalanced mitochondrial dynamics in a truly unbiased manner. Genome-wide RNAi screens in these cells will reveal novel modulators of mitochondrial dynamics. Taken together, this work aims to understand the metabolic pathways that control mitochondrial morphology and to develop a new technology to identify yet unknown modulators of mitochondrial dynamics.;1375000;1375000;ERC-2016-STG;/ERC-STG;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FR;;;;1;0;0;1;0;0 199926;690945;CARTHER;SIGNED;H2020-EU.1.3.3.;MSCA-RISE-2015;H2020;Carbon-based nano-materials for theranostic application;2016-01-01;2019-12-31;;Our proposal aims to carry out a systematic interdisciplinary study of carbon-based nanomaterials, such as: carbon fluoroxide nanoparticles, carbon nanotubes, graphene and nanodiamonds for advanced theranostic application. Their uptake efficiency and specific localization in biological cells depending on intentionally designed surface chemistry will be studied in details. Extremely rich physico-chemical properties of the carbon-based nanomaterials will allow their application as multi-modal bio-imaging agents. Indeed, in addition to their well-known remarkable luminescent properties, two original bio-imaging approaches based on photo-induced electrical and acoustic effects will be developed in frames of our project. Moreover, the photo-exciting sources used for the bio-imaging purpose will be simultaneously used for therapy of cancer cells and tissues containing the carbon nanomaterials. Strongly complementary research experiences of the international partners involved in this project as well as high degree of cooperative integration between them will allow a deep scientific study of the theranostic potential of the carbon nanomaterials. Finally, active participation of the Ray Technique Ltd industrial company in the project consortium will allow building of strategies for economic realizations of the innovative achievements succeeded by the partners.;891000;891000;H2020-MSCA-RISE-2015;/MSCA-RISE;INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE LYON;FR;"UNIVERSITE LYON 1 CLAUDE BERNARD;CORPORATION SCIENCE PARK TARAS SHEVCHENKO UNIVERSITY OF KYIV;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;RAY TECHNIQUES LTD;ASTON UNIVERSITY";"FR;UA;IL;UK";;1;0;0;1;0;0 198506;675137;MyFUN;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2015-ETN;H2020;Myopia: Fundamental understanding needed;2016-01-01;2019-12-31;;The proposed ETN “Myopia: fundamental understanding needed” (MyFUN) provides an international, interdisciplinary platform to train young scientists at the interface of physics and biology, to study unresolved questions about the visual control of eye growth. It has been extensively documented that the growth of the eye is controlled by closed-loop visual feedback, using retinal image defocus as an error signal. However, with tense education, predominant indoor activity and extensive near work, the eyes of young people grow too long and become near-sighted (myopic), reaching a prevalence of 95% in some Asian cities and 50% at German universities. While myopia is clearly a civilization disorder, it is strikingly unclear by which visual stimuli it is triggered, and how it can be stopped. Emerging optical interventions have still only moderate effects. There are fundamental questions, like “Why does myopia not limit itself?”, “Why does undercorrection not reduce its progression?”, “Why are the effects of new spectacle designs to inhibit myopia so small?”, “What determines when it starts and can we find biological markers to predict myopia in individual cases?”. We propose a scheme of novel experiments, divided into 14 research projects that all have sufficient scientific depth and merit to merge into 14 successful PhD theses. The answers to the research questions will fundamentally improve our understanding of myopia, will be recognized worldwide and will represent a major contribution of the European Community to the global problem of the rising incidence of myopia. Our consortium consists of 7 Beneficiaries, combining the expertise of 5 academic partners with excellent research and teaching records and 2 fully integrated private sector partners. MyFUN will be supported by a management team experienced in multi-site training activities and counselled by a scientifically accomplished External Advisory Board.;3544115,04;3544115,04;H2020-MSCA-ITN-2015;/MSCA-ITN-ETN;EBERHARD KARLS UNIVERSITAET TUEBINGEN;DE;"UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN;KUNGLIGA TEKNISKA HOEGSKOLAN;VOPTICA S.L.;CARL ZEISS VISION INTERNATIONAL GMBH;AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS;UNIVERSIDAD DE MURCIA";"IE;SE;ES;DE";;1;0;0;1;0;0 195345;656872;INAME;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Imaging nucleic acid metabolism in cells;2016-01-04;2018-01-03;;In this project I, Pawan Kumar, a Nucleic Acid Chemist seek to team up with a pioneer in Nucleic Acid Chemistry and Biology (Professor Tom Brown) to carry out a highly interdisciplinary study at the University of Oxford to obtain deeper insights into DNA and RNA synthesis and metabolism in living cells and its application to cancer research. I propose to detect and quantify nucleic acid synthesis in proliferating cells by fluorescence without the requirement for toxic metal ions or antibodies. Earlier known methods such as [3H]thymidine and 5-bromo-2'-deoxyuridine labelling are either slow and labour intensive or require the use of harsh conditions. Incorporation of 5-ethynyl-2'-deoxyuridine into newly synthesized DNA and its subsequent detection with an azide derivative of a fluorescent dye under copper catalyzed alkyne azide cycloaddition (CuAAC) reaction conditions presents a better alternative. However, cytotoxicity of copper salts restricts its use for living cells. I will use the strain promoted alkyne azide cycloaddition reaction, Diels-Alder reaction, and inverse electron demand Diels-Alder reaction to study cellular DNA and RNA. None of these reactions require the use of toxic metal salts. I will develop the conditions under which both DNA and RNA will be stable, so that it will be possible to isolate intact fluorescent nucleic acids from cells for detailed analysis. I will prepare the modified nucleosides and use them to label newly synthesized DNA and RNA in cells enabling their detection by reaction with fluorophores by using metal free click ligation reactions. The study will provide a better understanding of the mechanisms regulating DNA replication and the interplay between transcription and DNA replication. In the project I will develop techniques to provide information on the toxic effect of antimetabolites used commonly in anti-cancer therapies, and for identifying the mechanisms of viral replication and understanding the viral life cycle.;195454,8;195454,8;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;UK;;;;1;0;0;1;0;0 195236;656259;PoreSelect;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Macroporous Polymer Monoliths as a Low-Cost Bioanalytical Platform for Biopharmaceutical Glycoprotein;2016-02-01;2018-01-31;;Glycoprotein therapeutics are widely seen as the next generation of drugs. 80% of new therapeutic drugs in phase 3 development are ‘biologics’. However, the early detection of critical glycosylation changes in biopharma pro-duction (i.e. in the drug producing cells) and the rapid and sensitive identification and separation of closely relat-ed protein-drug glycoforms presents an industry wide problem. This project aims to develop a low-cost and easy-to-produce glycopeptide separation platform. This will be based on highly porous polyHIPE structures obtained from fast and scalable polymerisation and subsequently functionalised with reactive groups. The latter will be employed in the conjugation with novel recombinant lectins that have very selective carbohydrate-binding prop-erties. The separation of closely related glycoproteins will be investigated. Moreover, the integration of the lectin conjugated porous polymers into a device format will be addressed. This is a highly interdisciplinary project at the interface of polymer and material science, biotechnology and separation science. The applicants diverse experi-ence in academic and industrially informed projects makes him an ideal match for this project. It provides a unique environment for the researcher to develop his skills supported by unique scientific and complementary training and accelerate his academic career in applied material science. The dissemination of research results will target the professional audience as well the general public through outreach activities.;175866;175866;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;ROYAL COLLEGE OF SURGEONS IN IRELAND;IE;DUBLIN CITY UNIVERSITY;IE;;1;0;0;1;0;0 193489;637386;SYMPLECTIC;SIGNED;H2020-EU.1.1.;ERC-StG-2014;H2020;Symplectic Measurements and Hamiltonian Dynamics;2015-03-01;2020-02-29;;"Symplectic geometry combines a broad spectrum of interrelated disciplines lying in the mainstream of modern mathematics. The past two decades have given rise to several exciting developments in this field, which introduced new mathematical tools and opened challenging new questions. Nowadays symplectic geometry reaches out to an amazingly wide range of areas, such as differential and algebraic geometry, complex analysis, dynamical systems, as well as quantum mechanics, and string theory. Moreover, symplectic geometry serves as a basis for Hamiltonian dynamics, a discipline providing efficient tools for modeling a variety of physical and technological processes, such as orbital motion of satellites (telecommunication and GPS navigation), and propagation of light in optical fibers (with significant applications to medicine). The proposed research is composed of several innovative studies in the frontier of symplectic geometry and Hamiltonian dynamics, which are of highly significant interest in both fields. These studies have strong interactions on a variety of topics that lie at the heart of contemporary symplectic geometry, such as symplectic embedding questions, the geometry of Hofer’s metric, Lagrangian intersection problems, and the theory of symplectic capacities. My research objectives are twofold. First, to solve the open research questions described below, which I consider to be pivotal in the field. Some of these questions have already been studied intensively, and progress toward solving them would be of considerable significance. Second, some of the studies in this proposal are interdisciplinary by nature, and use symplectic tools in order to address major open questions in other fields, such as the famous Mahler conjecture in convex geometry. My goal is to deepen the connections between symplectic geometry and these fields, thus creating a powerful framework that will allow the consideration of questions currently unattainable.";1221921;1221921;ERC-2014-STG;/ERC-STG;TEL AVIV UNIVERSITY;IL;;;;1;0;0;1;0;0 196978;665564;CIRCLE;SIGNED;H2020-EU.1.2.1.;FETOPEN-2-2014;H2020;Coordinating European Research on Molecular Communications;2015-06-01;2017-05-31;;"In recent years, several research groups have been created in the emerging research area of molecular communications. This is seen as a fundamental enabler for nano-scale networked devices. The heterogeneity of the biological environments that can host nano-scale communications has produced different proposals (e.g. neuronal networks, molecular diffusion, flow-based carrier mobility) analyzed by means of different research approaches and tools (different analytical models, simulators, lab experiments). For this reason, the need of integrating research activities at an EU level has emerged. The main objective of the CIRCLE is to integrate islands of heterogeneous research activities in a common research framework. The nature of the proposal is therefore strategic for the EU research objectives, highly interdisciplinary, inclusive of any input coming from any research activities that can contribute to identifying a research roadmap for the future years and feasible future exploitation plans. In the short term, CIRCLE will facilitate the creation of an EU wide Molecular Communications (CIRCLE) forum and provide a support infrastructure for coordination of research across Europe. In the medium term, it will foster knowledge sharing via the CIRCLE forum and a dedicated web portal. This will focus on the sharing of both research methodologies and simulation code repositories. It will establish expert working groups in different research topics within the Molecular Communications domain and develop strategic Roadmaps for both academic research and industry involvement. In the long term, CIRCLE will push the Roadmaps at a Member State and EU level to ensure Molecular Communications research converges rapidly towards feasible products of interest in the marketplace.";532336;532336;H2020-FETOPEN-2014-CSA;/CSA;WATERFORD INSTITUTE OF TECHNOLOGY;IE;"THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;TTY-SAATIO;INTERUNIVERSITAIR MICRO-ELECTRONICA CENTRUM;KOC UNIVERSITY;UNIVERSITAIR MEDISCH CENTRUM UTRECHT;UNIVERSITAT POLITECNICA DE CATALUNYA;UNIVERSITA DEGLI STUDI DI PERUGIA;CONSORZIO NAZIONALE INTERUNIVERSITARIO PER LE TELECOMUNICAZIONI;IMINDS";"UK;FI;BE;TR;NL;ES;IT";;1;0;0;1;0;0 195009;654906;ALHIS;CLOSED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Archaeology, Landscapes and Heritage in the Iberian Southeast;2015-06-01;2017-09-20;;This training-through-research project at the Institute of Heritage Sciences of the Spanish National Research Council (Incipit-CSIC), aims both to generate new scientific knowledge on the archaeology of the landscapes and the socio-political processes of the Final Iron Age and the Early Roman period, and to enhance their value for cultural heritage management and development in Murcia, in the Spanish Southeast. In this sense, this proposal aims to create a fruitful link between the applicant’s historical and archaeological research background and skills and the opportunities to learn and to develop a heritage outreach project. The interest of the project is due to both, the lack of landscapes studies which focus on the Iron Age in this region from a diachronical and landscape perspective, and the remarkable socio-political transformations undergone by the local communities in the period between the 5th and the 1st centuries BC. The landscape will be here understood like expression of the social and political interactions, but also like a space with an active role in their development, at different levels. All the evidences will be compiled, for the first time, through an interdisciplinary methodology (archaeological record, ancient texts, paleoenvironmental data, integration in a GIS, etc.) and will be analysed from a contextualized and comparative European perspective, which the regional research in this period lacks. Results will be disseminated by means of several impact publications but also beyond the strictly scientific environment, with the support of the host centre, the regional museums and other institutions. Regarding the heritage perspective this project aims to allow the applicant to learn how to re-direct all this knowledge towards a proper and effective management and communication of the important and rather unknown heritage value of those sites.;158121,6;158121,6;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS;ES;;;;1;0;0;1;0;0 215074;792600;SCIENCE-MINQ;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Developing Rapid Inquiry as a pedagogical framework for multimodal interactions in informal science settings;2019-01-01;2020-12-31;;"This project is firmly situated within the Learning Sciences – the interdisciplinary field that aims to further scientific understanding of learning and engage in the design and implementation of learning innovations; focusing on the area of Informal Science Learning – the study of science learning processes and outcomes in informal settings such as science centres. Bell et al. argue that a key challenge for science centres is to enable their visitors to link their emotional, sensory and cognitive interactions with the exhibits – known as multimodal experiences – to science-specific phenomena. This research aims to utilise the structure provided by inquiry-led scientific investigations to harness the engagement power of multimodal exhibits in science centres. To achieve this aim, we will work with science centre educators, science teachers and young people (aged 12-16) to: co-design a Rapid Inquiry framework; elicit user requirements; co-design interaction components that integrate multimodal interactions with exhibits; develop an Inquirer app and evaluate its impact; and develop a set of technical requirements and pedagogical guidelines that will enable science centres to adopt rapid multimodal inquiry as a pedagogical approach. Partnerships with science centres in the UK, local secondary schools and after-school science clubs will be established to secure maximum practical value and dissemination.";195454,8;195454,8;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;UNIVERSITY OF LEICESTER;UK;;;;1;0;0;1;0;0 215654;798565;RE-IMMUNE;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Intelligent Nano-encapsuled siRNA for Restoring Immune Cell Response to Cancer;2019-02-18;2022-02-17;;"WHY: To effectively bring siRNA-based therapeutic for cancer immunotherapy into the hands of clinicians requires the development of fundamentally new mechanisms to overcome current drawbacks. Accomplishing this will enable more efficient treatment with less side effects. WHAT: RE-IMMUNE is an interdisciplinary programme in which the field of nanomaterial and nucleic acid nanotechnology merge to develop intelligent nano- encapsulated siRNA for safe and efficient delivery of siRNA in cancer-associated immune cells, to re-program and shift the tumor microenvironment from pro to anti-tumoral. To achieve this goal, I will undertake a high risk/high gain programme at the forefront of nanomedicine. The leading idea is to overcome the drawbacks of naked siRNA by combining two synergic strategies that will protect siRNA until recognition of its target site. I will evaluate intracellular trafficking of siRNA nanodevices and the silencing effect. I will also investigate possible synergic effect of a siRNA cocktail able to target different genes at the same time. Finally, I will evaluate the re-immunoediting action in vivo. HOW: The challenge met by the proposed program is to provide a groundbreaking contribution to cancer treatment. To achieve these objectives, I will combine the different scientific backgrounds and expertise of two leading scientists. Prof. Frank Caruso (University of Melbourne) is a world-wide recognized expert on nanomaterials and biomedicine, and Prof. Francesco Ricci (University of Rome Tor Vergata) leads a young and dynamic group at the forefront of DNA nanotechnology for sensing and drug-delivery applications. The fellowship will proceed through a well-defined set of research and training tasks. Thanks to this MSC Fellowship, I will diversify my scientific knowledge and acquire cutting-edge competences (in nanomaterials, microscopy, and nanoscopy), as well as complementary skills, which will become the foundation of my scientific independence.";250518,6;250518,6;H2020-MSCA-IF-2017;/MSCA-IF-GF;UNIVERSITA DEGLI STUDI DI ROMA TORVERGATA;IT;;;;1;0;0;1;0;0 216029;770548;HRP-IAEA;SIGNED;H2020-EU.1.1.;ERC-2017-COG;H2020;Living with Radiation: The Role of the International Atomic Energy Agency in the History of Radiation Protection;2019-01-01;2023-12-31;;"This project addresses the central question of how the International Atomic Energy Agency, a diplomatic and political international organization, came to dominate scientific institutions with a long tradition in radiation protection. Despite the importance of international organizations for the development of postwar science there is no work on the history of radiation protection in relation to the development of the IAEA. The project addresses this lacuna in a groundbreaking way: it analyses what is usually treated as a strictly techno-scientific issue—how best to protect us from ionized radiation—using methods from history, philosophy, and sociology of science, and in the context of international history. The main hypothesis is that scientific knowledge about radiation protection has been shaped by diplomatic, social, economic, and political concerns. This approach casts new light on important aspects of postwar history of science, combining attention to state actors, science diplomacy, and the roles played by international organizations. Given the enormous interest in radiation protection the time is ripe for providing a comprehensive social, historical, and political study of the role of the IAEA in the field. The main objectives of the project are: • To retrace the international history of radiation protection after World War II, focusing especially on the Technical Assistance Programs of the IAEA; • To investigate the role of the IAEA in sponsoring knowledge production in the field of radiation protection in competition with other regulatory agencies; and • To analyze the standardization of instruments, objects, procedures, and technical vocabulary as the main strategy used by the IAEA for guiding radiation protection worldwide. The project advocates a 'diplomatic turn': diplomacy becomes analytical category in history of science. Highly interdisciplinary it brings together expertise from several disciplines, promising a significant advancement across them.";1999705;1999705;ERC-2017-COG;/ERC-COG;TECHNISCHE UNIVERSITAET BERLIN;DE;;;;1;0;0;1;0;0 216337;801378;MAGNIFY;SIGNED;H2020-EU.1.2.1.;FETOPEN-01-2016-2017;H2020;From nano to macro: a groundbreakIng actuation technology for robotic systems;2018-10-01;2022-09-30;;"The long-term vision of the MAGNIFY project is to design and realize a new generation of artificial muscles for robotic systems, characterized by high force-to-weight ratio, high flexibility, fast reacting properties, and intrinsic rigidity tuning. The scientific and technological breakthrough consists in using billions of artificial molecular machines, organized in polymer electrospun nanofibers and controlled by electrical stimuli, to realize an artificial macroscopic muscle. Thanks to this bottom- up methodology, the stimuli-controlled nanoscale movements of the collective molecular machines will be incrementally amplified up to the macro-scale in the artificial muscle. The breakthrough of the MAGNIFY project is certainly ambitious because it contains novel scientific and technological challenges in several scientific disciplines. The design of the artificial muscle from the nano-scale up to the macro-scale will be a concrete foundational breakthrough because it will establish an essential basis for a new kind of actuation technology and its future use in robotic systems, as never anticipated before. The MAGNIFY project is built upon the strong believe that interdisciplinarity is core to the development of artificial muscles. MAGNIFY requires experts at the different scales, namely, i) at the nano-scale: molecular/supramolecular chemists for the synthesis of molecular machines and their manipulation; ii) at the boundary between the nano- and the micro-scale: electrochemists, material/polymer scientists, mechanical/electrical engineers for the realization of the electrospun nanofibers and their electrical connections; iii) at the micro-scale and towards the macro-scale: mechanical/electrical engineers for the realization of the bundles of nanofibers; iv) at the macro-scale: roboticists for the realization and testing of prototypes of the new artificial muscle.";2922730;2922730;H2020-FETOPEN-1-2016-2017;/RIA;RIJKSUNIVERSITEIT GRONINGEN;NL;"CONSIGLIO NAZIONALE DELLE RICERCHE;ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS";"IT;FR";;1;0;0;1;0;0 216243;788970;CodingHeart;SIGNED;H2020-EU.1.1.;ERC-2017-ADG;H2020;Novel Coding Factors in Heart Disease;2019-01-01;2023-12-31;;Heart failure has become a worldwide epidemic with more than 23 million people affected resulting in devastating consequences for patients and an enormous burden on health care systems. One in five heart failure patients dies within a year of diagnosis and survival estimates after diagnosis are 50% and 10% at 5 and 10 years, respectively. Despite intensive investigation, the molecular mechanisms leading to heart failure remain poorly understood. We will narrow this critical gap in knowledge by proposing a previously unattainable, comprehensive approach to define the genomic architecture and functional consequences of newly identified micropeptides from multiple classes of RNAs that previously were classified to be non-coding in cardiac biology and heart failure. Our approach is unique and novel in several ways. Thematically, our studies focus on novel classes of orphan peptides and their role in heart failure that have not been discovered previously. Our approach relies on innovative interdisciplinary efforts of scientists working in molecular genetics, genomics, computational biology, and cardiovascular research to identify and characterize pathophysiological pathways that converge on these novel peptides. We will identify these short peptides by using genome-wide measures of active translation and will harness unique clinical resources to ensure human relevance. Analysis of animal and cell models coupled with state-of-the-art biochemical and genetic tools will elucidate the function of newly identified micropeptides within the molecular and cellular pathways of cardiac biology and failure. Through these efforts we will discern fundamental causes of maladaptive responses in the heart and strategies to monitor and limit these.;2319514;2319514;ERC-2017-ADG;/ERC-ADG;MAX-DELBRUCK-CENTRUM FUR MOLEKULAREMEDIZIN;DE;;;;1;0;0;1;0;0 215705;799112;Neuronetmir;CLOSED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Role of miR-129-5p and Rbfox1 crosstalk in neural network homeostasis;2018-07-01;2020-06-30;;"Imbalances between excitatory and inhibitory neural networks are a hallmark of several brain disorders including epilepsy. Current drug therapies for epilepsy are ineffective in a third of patients and none have disease-modifying effects. It is of high priority, therefore, to understand molecular/ genetic mechanisms responsible for epilepsy development and identify novel targets. The control of mRNA stability and translation is critical for proper neural network function. Here, RNA binding proteins (RBPs) and small noncoding RNAs called microRNAs (miRNA) act together to fine-tune levels of proteins critical for synaptic structure and function. These may represent important therapeutic targets since they regulate gene networks and exert broader actions that can generate more potent effects against seizures. Until now there has been no systematic analysis of miRNA, RBP crosstalk in the context of neural network stability in epilepsy. Building on my recent breakthrough studies showing miR-129-5p/Rbfox1 crosstalk in neural network homeostasis my project will explore the following objectives: First, identify targets regulated by miR-129-5p/Rbfox1 crosstalk in vivo; Second, functionally interrogate miR-129-5p/Rbfox1 crosstalk in neural network stability in vitro and in vivo; Third, investigate miR-129-5p and Rbfox1 function in human neural networks. To achieve these objectives I will apply my existing expertise as well as acquire new skills in a range of state-of-the-art interdisciplinary and cutting-edge techniques including single molecule imaging, proteomic analyses, multiple electrode arrays, human brain organotypic cultures and pre-clinical animal models. The results will establish RBPs, alongside miRNAs, as new mediators of epileptogenic network pathogenesis. Findings will also generate new targets for pre-clinical development and evidence of efficacy in human cells for disease-modifying therapies for epilepsy and disorders of neural network homeostasis.";187866;187866;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;ROYAL COLLEGE OF SURGEONS IN IRELAND;IE;;;;1;0;0;1;0;0 216225;788506;CALCULUS;SIGNED;H2020-EU.1.1.;ERC-2017-ADG;H2020;Commonsense and Anticipation enriched Learning of Continuous representations sUpporting Language UnderStanding;2018-09-01;2023-08-31;;Natural language understanding (NLU) by the machine is of large scientific, economic and social value. Humans perform the NLU task in an efficient way by relying on their capability to imagine or anticipate situations. They engage commonsense and world knowledge that is often acquired through perceptual experiences to make explicit what is left implicit in language. Inspired by these characteristics CALCULUS will design, implement and evaluate innovative paradigms supporting NLU, where it will combine old but powerful ideas for language understanding from the early days of artificial intelligence with new approaches from machine learning. The project focuses on the effective learning of anticipatory, continuous, non-symbolic representations of event frames and narrative structures of events that are trained on language and visual data. The grammatical structure of language is grounded in the geometric structure of visual data while embodying aspects of commonsense and world knowledge. The reusable representations are evaluated in a selection of NLU tasks requiring efficient real-time retrieval of the representations and parsing of the targeted written texts. Finally, we will evaluate the inference potential of the anticipatory representations in situations not seen in the training data and when inferring spatial and temporal information in metric real world spaces that is not mentioned in the processed language. The machine learning methods focus on learning latent variable models relying on Bayesian probabilistic models and neural networks and focus on settings with limited training data that are manually annotated. The best models will be integrated in a demonstrator that translates the language of stories to events happening in a 3-D virtual world. The PI has interdisciplinary expertise in natural language processing, joint processing of language and visual data, information retrieval and machine learning needed for the successful realization of the project.;2227500;2227500;ERC-2017-ADG;/ERC-ADG;KATHOLIEKE UNIVERSITEIT LEUVEN;BE;;;;1;0;0;1;0;0 216366;810701;LAMatCU;SIGNED;H2020-EU.4.c.;WIDESPREAD-03-2017;H2020;Establishing Laboratory of Advanced Materials at the Comenius University;2018-09-01;2023-08-31;;"The key objective of this proposal is to establish a new Laboratory for Advanced Materials (LAM) at Comenius University (CU) under the direction of the appointed ERA Chair holder. LAM is meant to be a world-class research interdisciplinary laboratory focused on advanced materials research, particularly for applications in the areas such as energy conversion and storage, electronics, and optoelectronics. Existence of LAM will: - strengthen the potential and the contribution of CU to this area of research in the wider ERA in tight connection to the central idea of the Work Programme - Spreading Excellence and Widening Participation - help counteracting the eminent brain drain Slovakia is experiencing by attracting brilliant young researchers from both Slovakia and abroad - consequently strengthen the position of CU as a leading research and educational institution in Slovakia as well as raise its significance in Europe The structure and management of LAM is designed to ensure its future self-sustainability and continuity of its research. Project funds will be utilized in establishing LAM and maintaining LAM's initial operation period, during which following actions will be taken to secure future financial sustainability: - Top-quality research personnel will be recruited bringing in international scientific collaborations. - External collaborations with the industry will be actively sought. - Opportunities to utilize research outputs as intellectual property and patents will be exploited. - Research grants connected to the area of research interests will be applied for. - Public outreach activities will be focused on stimulating interest and engagement among students. Within this scheme, the project funding will serve as the initial kick-start of a new internationally acclaimed prime research facility (LAM), activating the whole field of materials research at CU, thus having a positive long-term effect on the status of research excellence in Slovakia as well.";2496750;2496750;H2020-WIDESPREAD-03-2017-ERAChairs;/CSA;UNIVERZITA KOMENSKEHO V BRATISLAVE;SK;;;;1;0;0;1;0;0 216364;810660;SimEA;SIGNED;H2020-EU.4.c.;WIDESPREAD-03-2017;H2020;Modeling and Simulation for Engineering Applications;2019-01-01;2023-12-31;;"The project Modelling and Simulation for Engineering Applications (SimEA) aims to consolidate and upgrade the Computation-based Science and Technology Research Center (CaSToRC) of the Cyprus Institute (CyI) by attracting and establishing a team of outstanding researchers, led by a Professor of international caliber to maximally utilize and upgrade the existing facilities and pursue a program of research excellence and innovation. The SimEA ERA Chair will expand the research portfolio of CaSToRC to include computation-based engineering adding the missing technology leadership, collaborate with other research groups in Cyprus, the Eastern Mediterranean (EM) and internationally, enrich the educational programs of CaSToRC and CyI and set the appropriate mechanisms to forge collaboration with industry. The alignment of these objectives with the Cyprus smart specialization strategy and European priorities in Energy, Health and Information Technologies provides previously untapped funding opportunities for CaSToRC that would help sustain the team beyond the lifetime of the project. CyI strongly supports the creation of the ERA Chair by pledging a tenured faculty position and a grant of 700,000 Euro for infrastructure upgrades to best serve the research and innovation programs of the project. The international character and interdisciplinary environment of CyI, its strong funding track record, the attractive remuneration, job security and infrastructure grant offered are key elements that conduce to attracting an ERA Chair of the highest international standing. In turn, such a scholar will build a vibrant research group, bring competitive funding and spearhead entrepreneurship and industrial collaboration consolidating CaSToRC as a hub for computational science and engineering in Cyprus and the EM in alignment with the center’s mission to help the nation transform to a knowledge-based economy and to act as a gateway for advanced computing between Europe and the EM region.";2499250;2499250;H2020-WIDESPREAD-03-2017-ERAChairs;/CSA;THE CYPRUS INSTITUTE;CY;;;;1;0;0;1;0;0 214549;792945;EcoGemCoat;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Smart anticorrosion coatings based on nanocontainers loaded with novel, eco-friendly cationic gemini surfactants as efficient corrosion inhibitors for carbon steel in seawater.;2018-09-03;2020-09-02;;"The project, EcoGemCoat, involves the preparation of smart anticorrosion coatings based on mesoporous silica nanocontainers loaded with innovative, eco-friendly cationic gemini surfactants as high efficient corrosion inhibitors of carbon steel in seawater with the potential application in marine and offshore industry. The main aim of EcoGemCoat will be achieved by performing four specific goals: 1) preparation of novel corrosion inhibitors (synthesis of the surfactants and structure confirmation) with low toxicity; 2) testing of the inhibitors (aggregation behaviour tests, biological tests, electrochemical corrosion inhibition tests); 3) preparation of smart coatings (immobilization of surfactants, characterization of nanocontainers, release study, smart coating preparation); 4) corrosion, mechanical and biological tests of the developed coatings. The proposed project involves different areas of science as organic chemistry (synthesis of inhibitors), analytical chemistry (aggregation behaviour, release study), electrochemistry (electrochemical corrosion tests), environmental science (toxicity and bioaccumulation tests) and materials science (mechanical tests), which makes topic interdisciplinary in nature. The research of encapsulation of the cationic gemini surfactants will be attempted for the first time, as well as the resulting type of smart anticorrosion coatings. Furthermore, the use of green inhibitors as additives of smart and eco-friendly coatings might change the coating Industry paradigm, answering to some of the EU societal challenges for the present and future decades. Equally relevant is the high quality of training to which the candidate will have access, thus fostering a reinforcement of the candidate’s position in the scientific community as an independent researcher and will ultimately have a significant positive impact on the fellow's future career in corrosion research.";148635,6;148635,6;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;UNIVERSIDADE DE AVEIRO;PT;;;;1;0;0;1;0;0 216277;794254;HELPHERGEN;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;THE GENETIC BASIS OF MATING BEHAVIOR: PHEROMONE COMMUNICATION IN NOCTUID MOTHS;2018-10-01;2020-09-30;;"The genetic architecture of behavior is a major topic in biology, but remains poorly understood. The behaviors with the most dramatic effect on animal fitness are those involved in mate attraction and courtship, which are directly related to reproductive success. Males and females share a genome but have idiosyncratic roles in courtship rituals; mating traits thus experience sex-specific selection regimes. Variation at the gene expression level can facilitate sex-specific trait evolution to some degree. However, sex-specific traits inevitably covary, leading to correlated evolutionary responses (pleiotropy). Here I propose an innovative and multidisciplinary framework integrating a quantitative genetic approach to multivariate phenotypic evolution with functional genetic experiments. The key objective is to reveal how genes controlling traits involved in mating behavior can have widespread phenotypic effects across sexes by quantitative genetic measurements of pheromone communication variation in wild-type and knock-out lines of noctuid moths. I will examine the correlated evolution of pheromone signals in male and female moths and identify candidate genes using differential expression analyses. Then, I will examine the phenotypic effects using the cutting-edge CRISPR/Cas9 system and a quantitative genetic framework to test behavioral effects. The proposed research combines behavioral, quantitative genetic, and gene editing techniques and will make headway towards understanding the genotype-phenotype map of mating behavior. I will be based at the Institute for Biodiversity and Ecosystem Dynamics (IBED), an excellent interdisciplinary research institute focusing on functional biodiversity at the University of Amsterdam (UvA). Via training-through-research and a secondment at a collaborative lab of the host supervisor, I will learn essential, state-of-the-art skills including genetic engineering, gene expression assays, and advanced bioinformatic scripting.";177598,8;177598,8;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;UNIVERSITEIT VAN AMSTERDAM;NL;;;;1;0;0;1;0;0 216339;801423;MyoChip;SIGNED;H2020-EU.1.2.1.;FETOPEN-01-2016-2017;H2020;Building a 3D innervated and irrigated muscle on a chip.;2018-11-01;2022-10-31;;The aim of the MyoChip project is to build a 3D human skeletal muscle irrigated by vasculature and innervated by neurons. The reconstituted 3D muscle will mirror the architecture and function found in vivo, namely in shape, contractility and microenvironment, while irrigation by a vascular network and innervation by human motor neurons will bring additional physiologic pertinence to it. This organ-on-a-chip technology will have numerous applications including but not limited to research on muscle building and aging, drug testing and screening, as well as prosthetics and biorobotics. The feasibility of the project relies on the interdisciplinary approach which joins a team of cell biologists, material engineers, experts in microfluidics and mathematical modellers. The architecture of skeletal muscle and its regenerative capabilities make muscle a prime candidate to push the 3D tissue engineering field. As such the project will lay the technical, material and methodological foundations to tackle the next generation of complex organ-on-a-chip systems that the MyoChip consortium can exploit for the generation of highly complex 3D in vitro systems of many organs.;3153553,74;3153553,74;H2020-FETOPEN-1-2016-2017;/RIA;INSTITUTO DE MEDICINA MOLECULAR JOAO LOBO ANTUNES;PT;"FLUIGENT SA;INSTITUT CURIE;THE UNIVERSITY OF EDINBURGH";"FR;UK";;1;0;0;1;0;0 216124;785793;MaCoTech;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Material counting technologies in numerical cognition;2018-06-15;2020-06-14;;"Material counting technologies (MaCoTech) play a critical role in developing human numerical concepts like numbers, numerical relations, and arithmetical operations. Yet today, our understanding of how these concepts emerge is still very restricted, as the influential effects of prehistoric MaCoTech and Ancient Near Eastern (ANE) mathematics are difficult to assess and have been mostly neglected in modern-day research. The comparison of ANE MaCoTech to its extant counterparts of Oceania will allow investigating the impact of multiple MaCoTech on numerical elaboration, and to gain a deeper understanding of the evolution of numerical concepts in socio-historical contexts. This will include the first-ever generation of a dataset of ANE and Oceanian MaCoTech and the development of innovative strategies for cross-cultural data analysis. The project will apply state-of-the-art paradigms on the nature of human cognition to improve our understanding of how MaCoTech structure numerical concepts, which will generate novel insights into numerical origins and the role of materiality in human cognition. It will also engender new understandings of psychological–behavioral–material interactions with potential utility in cognitive-psychological research. As a cognitive archaeologist with a strong background in the materiality of numbers, I want to be among the first to work at a novel interdisciplinary crossway connecting the fields of archaeology, psychology, anthropology, linguistics, and Assyriology. With a renowned researcher in numerical cognition as my supervisor and my own expertise in ANE number systems, ANE archaeology, and philosophy of mind, this will bring me in the optimal position to foster an international high-level career in numerical cognition research at the interface of multiple disciplines. This will be substantiated by the mutual transfer of knowledge as well as national and international long-term research synergies.";208400,4;208400,4;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;UNIVERSITETET I BERGEN;NO;;;;1;0;0;1;0;0 216370;811040;COMPETE;SIGNED;H2020-EU.4.c.;WIDESPREAD-03-2017;H2020;Chair Of Micro Process Engineering and TEchnology;2019-01-01;2023-12-31;;The project will establish the ERA Chair Of Micro Process Engineering and TEchnology – COMPETE. It is designed to capitalise on microfluidics research and technology, an existing knowledge base of University of Ljubljana (UL) to a leading European hub of microfluidics expertise. Microfluidics offers huge potential for new solutions in biomedicine, biotechnology, food quality assessment and environmental protection, and is directly in line with the Slovenian Smart Specialization Strategy. To achieve this ambition, the Chair will integrate micro-process engineering disciplines – chemical, mechanical and electrical engineering – with basic research in biophysics, chemistry and microbiology in order to overcome the main barriers for research excellence in this highly interdisciplinary field. COMPETE will address the lack of institutional organization connecting research teams and infrastructure within UL, lack of financing, and practice not in line with open recruitment policy. Attracting a Chair Holder with excellent research credentials and leadership competences, thus creating a research team with broad expertise and wide network for collaboration that will greatly improve the culture of research and research performance at UL. Cooperation with other research, industrial, governmental and non-governmental entities and dissemination are key activities that will complement internal structural changes and help build sustainability and a wider impact of the Chair as a leading regional centre for micro-process engineering. Sustainability will be granted by research funding procurement for projects, structured cooperation with industrial and public research and educational entities, establishment of a new study field in the doctoral programs at UL, PhD summer school and other training programs. By setting a best practice example and through a well-thought outreach campaign the project will stimulate structural changes throughout UL.;2500450;2500000;H2020-WIDESPREAD-03-2017-ERAChairs;/CSA;UNIVERZA V LJUBLJANI;SI;;;;1;0;0;1;0;0 212201;759063;WFNQMC;SIGNED;H2020-EU.1.1.;ERC-2017-STG;H2020;Development of a Novel Computational Toolbox for Stochastic Electronic Structure in Chemistry and Condensed Matter;2018-02-01;2023-01-31;;Atomistic computational modelling is increasingly an integral component of almost all areas of chemistry, physics and materials science, especially as its predictive ability improves. However, not all systems are equal when it comes to the predictive capabilities of current methods, and many systems are too large or many-body effects too complex to be routinely tractable. The result is that the promise of ‘materials by design’, deduction of reaction pathways or routine simulation on a par with experimental accuracy has not in general come to fruition. This ambitious proposal aims to address this, with development of a suite of novel approaches to stochastically sample the wavefunction. Recent work by the PI has already made huge strides in this direction, with an emerging approach in quantum chemical space having remarkable success for accurate solutions of small problems. Here, we first propose a number of novel developments to order to extend this approach from a tool for small systems to a widespread disruptive technology, with application to a variety of challenging problems. This involves development of the scope, scaling, accuracy and capabilities of this sampling, including admitting time-dependent, spectral and relativistic extensions. Next, we aim to take the successful philosophy of this sampling and exploit its powerful approach in order to reformulate a number of well-established electronic structure tools. Allowing stochasticity has the potential to yield low-scaling formulations of these methods, able to naturally exploit inherent sparsity, and have a revolutionary impact on their use and success. This proposal is highly interdisciplinary, spanning a range of applications and techniques in quantum chemistry, condensed matter and materials science, brought together under the banner of exploiting inherent sparsity by establishing a new paradigm of stochastic tools for correlated electrons, with the opportunity for tremendous impact in a number of fields.;1500000;1500000;ERC-2017-STG;/ERC-STG;KING'S COLLEGE LONDON;UK;;;;1;0;0;1;0;0 212401;773521;SMARTFISH;SIGNED;H2020-EU.3.2.3.;SFS-22-2017;H2020;Smart fisheries technologies for an efficient, compliant and environmentally friendly fishing sector;2018-01-01;2021-12-31;;"The objective of SMARTFISH is to develop, test and promote a suite of high-tech systems for the EU fishing sector, to optimize resource efficiency, to improve automatic data collection for fish stock assessment, to provide evidence of compliance with fishery regulations and to reduce ecological impact. SMARTFISH exploits technological developments in machine vision, camera technology, data processing, machine learning, artificial intelligence, big data analysis, smartphones/tablets, LED technology, acoustics and ROV technology to build systems for monitoring, analyzing and improving processes for all facets of the fishing sector, from extraction, to assessment, to monitoring and control. The SMARTFISH systems will: - assist fishermen in making informed decisions during pre-catch, catching, and post-catch phases of the extraction process. This improves catch efficiencies and compositions in fisheries across the EU, leading to improved economic efficiency while reducing unintended fish mortality, unnecessary fishing pressure and ecosystem damage. - provide new data for stock assessment from commercial fishing and improve the quality and quantity of data that comes from traditional assessment surveys. This provides more accurate assessment of currently assessed stocks and allow the assessment of data-poor stocks. - permit the automatic collection of catch data to ensure compliance with fisheries management regulations. The SMARTFISH systems are tested and demonstrated in several EU fisheries. This contributes to promoting the uptake of the systems by extraction sector and fisheries agencies. An interdisciplinary consortium with technology developers and instrument suppliers, fishing companies, research and fisheries management institutes and universities will realize SMARTFISH. They are active at national and international levels and well placed to ensure the uptake of SMARTFISH systems by fishing industry and fisheries managers and stock assessment scientists.";6961540;5976764,51;H2020-SFS-2017-1;/IA;SINTEF OCEAN AS;NO;"UNIVERSITY OF EAST ANGLIA;INTERFISH PRODUCER ORGANISATION LIMITED;LARRASMENDI BI SOCIEDAD LIMITADA;NERGARD HAVFISKE AS;STIFTELSEN SINTEF;MERSIN UNIVERSITESI;PATXIKU BERRIA CB;SAFETYNET TECHNOLOGIES LIMITED;THE SECRETARY OF STATE FOR ENVIRONMENT, FOOD AND RURAL AFFAIRS;MARINE SCOTLAND;MARPORT FRANCE;ZUNIBAL SL;DANMARKS TEKNISKE UNIVERSITET;FUNDACION AZTI - AZTI FUNDAZIOA;UNIVERSITY OF CUKUROVA;NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU;MELBU SYSTEMS AS";"UK;ES;NO;TR;FR;DK";;1;0;0;1;0;0 211847;757850;BioNet;SIGNED;H2020-EU.1.1.;ERC-2017-STG;H2020;Dynamical Redesign of Biomolecular Networks;2018-02-01;2023-01-31;;Enzymes created by Nature are still more selective and can be orders of magnitude more efficient than man-made catalysts, in spite of recent advances in the design of de novo catalysts and in enzyme redesign. The optimal engineering of either small molecular or of complex biological catalysts requires both (i) accurate quantitative computational methods capable of a priori assessing catalytic efficiency, and (ii) molecular design principles and corresponding algorithms to achieve, understand and control biomolecular catalytic function and mechanisms. Presently, the computational design of biocatalysts is challenging due to the need for accurate yet computationally-intensive quantum mechanical calculations of bond formation and cleavage, as well as to the requirement for proper statistical sampling over very many degrees of freedom. Pioneering enhanced sampling and analysis methods have been developed to address crucial challenges bridging the gap between the available simulation length and the biologically relevant timescales. However, biased simulations do not generally permit the direct calculation of kinetic information. Recently, I and others pioneered simulation tools that can enable not only accurate calculations of free energies, but also of the intrinsic molecular kinetics and the underlying reaction mechanisms as well. I propose to develop more robust, automatic, and system-tailored sampling algorithms that are optimal in each case. I will use our kinetics-based methods to develop a novel theoretical framework to address catalytic efficiency and to establish molecular design principles to key design problems for new bio-inspired nanocatalysts, and to identify and characterize small molecule modulators of enzyme activity. This is a highly interdisciplinary project that will enable fundamental advances in molecular simulations and will unveil the physical principles that will lead to design and control of catalysis with Nature-like efficiency.;1499999;1499999;ERC-2017-STG;/ERC-STG;KING'S COLLEGE LONDON;UK;;;;1;0;0;1;0;0 211902;765703;DNA-Robotics;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2017;H2020;DNA-Based Modular Nanorobotics;2018-01-01;2021-12-31;;Robotic systems essentially comprise sensors and actuators connected to and coordinated by an information-processing unit. These principles apply to the human scale robotic systems that currently transform the way we work and live. With DNA-Based Modular Robotics (DNA-Robotics) we will take the first steps to scale advanced robotic behavior to the molecular scale for future medical and technological applications. DNA-Robotics brings together the leading research groups in DNA nanotechnology in Europe to collectively develop an integrated and modular robotic platform and demonstrate applications of the novel technology. DNA-based construction is a natural modular platform, which via the programmability of sequence design and self-assembly allows different structural and functional motifs to be flexibly combined. DNA modules will be developed with a range of novel functions for sensing, actuation and intra-system communication and computing, implementing all of the typical components required for a robotic system at the molecular level. Our overall goal is the creation of the first “industry standard” for modular robotics by the establishment of a modular “plug-and-play” platform that allows the construction of custom-made nanorobots for advanced applications in research and industry. The ESRs will be trained in and develop functional modules that in close collaboration among the ESRs and Partners will be assembled to advanced molecular robots. The highly interdisciplinary research and training program will exploit the synergy between the different competences of the Partners. The innovative and applied focus is supported by the involvement of the company ATDBio as Beneficiary and five companies as Partner Organization that will also provide complementary skills training and intersectoral exposure of the ESRs. This proposal takes the first steps for future application of nanoscale robots in research and industry and will train future generations of researchers in this field.;3979632,96;3979632,96;H2020-MSCA-ITN-2017;/MSCA-ITN-ETN;AARHUS UNIVERSITET;DK;"UNIVERSITA DEGLI STUDI DI ROMA TORVERGATA;LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN;ATDBIO LIMITED;TECHNISCHE UNIVERSITAET MUENCHEN;KAROLINSKA INSTITUTET;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD";"IT;DE;UK;SE";;1;0;0;1;0;0 211887;765266;LightDyNAmics;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2017;H2020;DNA as a training platform for photodynamic processes in soft materials;2018-04-01;2022-03-31;;"Light interaction with biomaterials is the driving mechanism of fundamental biological processes, from photosynthesis to DNA photodamage, and is a powerful tool in biomedicine for analytical, diagnostic and therapeutic purposes. The main goal of LightDyNAmics is to achieve a complete understanding of the ultrafast dynamical processes at the molecular scale induced by UV light absorption in DNA, and to unveil the mechanisms leading to photodamage of the genetic code. At the same time, our project will transfer this knowledge on light-matter interaction to a broad class of optoelectronic materials, highly relevant for Europe`s high-tech industries. LightDyNAmics is an academia-industry research environment training 15 Early Stage Researchers (ESRs) by crossing the traditional border between theoretical and experimental expertise. This will be achieved by performing independent, yet interrelated and complementary research projects focussed on photoactivated dynamics of DNA, and by developing a variety of new spectroscopic and computational methods. For all the ESRs, personalised training in advanced techniques will be combined with a broad common interdisciplinary background on dynamical processes in bio-macromolecules. The consortium brings together 10 leading academic groups with multidisciplinary expertise (chemistry, physics, biology) and a unique blend of experimental and computational skills. 6 innovative companies, from SMEs specialised in click-chemistry and in biosensors to a pharma industry, will be fully integrated in the research and training programme and help promote technological exploitation of its results. LightDyNAmics will develop innovative molecular probes for DNA/protein interaction, paving the way to new diagnostic tools and new drugs. The understanding of light interaction with organic molecules will impact on basic sciences, from biochemistry to nanosciences, and on industrial applications ranging from healthcare to photonic technologies.";3827591,28;3827591,28;H2020-MSCA-ITN-2017;/MSCA-ITN-ETN;CONSIGLIO NAZIONALE DELLE RICERCHE;IT;"LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN;AstraZeneca UK Limited;UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN;Masarykova univerzita;UNIVERSITAT WIEN;UNIVERSITY OF DURHAM;BASECLICK GMBH;DYNAMIC BIOSENSORS GMBH;KEMIJSKI INSTITUT;POLITECNICO DI MILANO;ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS";"DE;UK;IE;CZ;AT;SI;IT;FR";;1;0;0;1;0;0 211640;765355;GLOMO;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2017;H2020;Global mobility of employees;2018-01-01;2021-12-31;;"Promoting labour mobility across Europe is a central objective of the Europe 2020 Strategy and it aims to tackle increasing labour and skill shortages in the EU. Cross-border labour mobility is expected to benefit both individual citizens, employers and the aggregate economy. In addition, intra-EU mobility is a means to foster European integration. Although migration into OECD countries increases, driven largely by people moving within the EU, migration into and within Europe is still short of target levels. Despite a favourable legal framework for mobility, migrants still face a wide range of problems and obstacles that hamper cross-border labour mobility. Employment prospects for immigrants are below those of natives and overqualification, i.e. employment below skill levels, is widespread in most European countries. Consequently, the growth potential of immigrants is far from realised. Little is known about transnational mobility patterns and the length of migration episodes as well as about retention processes of foreign employees. There is considerable scope to make existing labour mobility more efficient and beneficial for all parties involved. GLOMO’s focus is on global mobility into EU countries and within the EU and its impact on careers. The policy making white papers and research suggest that the future Europe will witness even higher and more natural mobility. To assure that Europe is ready for it, our objectives are (a) to systematically generate knowledge about the mobility phenomenon and its implications (success factors, effects and added value); (b) provide trainings to (further) develop early-stage and senior researchers understanding the complex multidisciplinary phenomenon of mobility, and (c) suggest relevant implications for individuals, organisations, the European societies and economies. The joint research and training programme will be conducted within an interdisciplinary and intersectoral network of experts in the field.";3947612,4;3947612,4;H2020-MSCA-ITN-2017;/MSCA-ITN-ETN;OTTO-FRIEDRICH-UNIVERSITAET BAMBERG;DE;"AIRBUS SAS;VAASAN YLIOPISTO;STICHTING VU;TOULOUSE BUSINESS SCHOOL -TBS;COPENHAGEN BUSINESS SCHOOL;INSTITUT FUER ARBEITSMARKT- UND BERUFSFORSCHUNG (IAB) DER BUNDESAGENTUR FUER ARBEIT;CRANFIELD UNIVERSITY";"FR;FI;NL;DK;DE;UK";;1;0;0;1;0;0 209337;750642;PHOTO_IMS;CLOSED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;The use of mass spectrometry and optical methods to determine the influence of cofactors on the structure and stability of proteins;2018-03-01;2020-02-29;;"This fellowship will use novel instrumentation to define the role of cofactors on the structure and stability of proteins. We have recently adapted a commercially available Synapt ion mobility mass spectrometer to allow it to perform optical measurements on conformer and mass selected ions, in collaboration with Waters Corp. The heart of this instrument is the ion mobility cell, IM-MS measurements are possible in this instrument, as for any Synapt mass spectrometer, but uniquely we are able to trap ions that have been conformer selected, to allow optical measurements in a so called ‘photo SRIG’ (stacked ring ion guide). Such optical measurements can take several forms, including IR-spectroscopy, UV/Vis-spectroscopy, which will provide structural analysis of co-factors and coenzymes, photo-dissociation to sequence the proteins as well as fluorescence to probe global conformations. Molecular mechanics calculations will generate structures to compare with those determined experimentally. This MC fellow will use this novel instrument to examine the role of cofactors on the conformations of proteins, by making measurements on the cofactor alone, the apo and the holo form of the protein. The MC fellow will be trained in biological mass spectrometry, in optical methods and in molecular mechanics. They will spend a secondment at Waters developing software to best interpret the data from this instrument. This cutting edge interdisciplinary science program is world leading and will train this fellow with a set of skills highly desirable both in academia and in industry.";195454,8;195454,8;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;THE UNIVERSITY OF MANCHESTER;UK;;;;1;0;0;1;0;0 209679;753487;DYNAMO;CLOSED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Structural Dynamics of Membrane Receptors at native-like conditions;2018-03-01;2020-02-29;;Proteins embedded in cell membranes are vital signaling and trafficking platforms connecting the outside to the inside of a cell, and functioning as primary drug targets. DYNAMO is an integrative dynamic structural biology project, with the ambitious goal of developing and implementing comprehensive experimental and computational approaches for studying the structural dynamics of membrane receptors (MRs) and their complexes at native-like conditions. DYNAMO is highly interdisciplinary, combining protein chemistry and computational physics to study dynamical processes underlying the function of MRs, and is designed to combine the expertise of the fellow and host. The project will establish an integrated platform based on the nanodisc-technology and the combined use of low- and high-resolution structural biology techniques to bring unique and alternative insights into the structural dynamics of MRs containing ”fuzzy” (i.e highly flexible) domains, and the role this plays in functional signaling assemblies. In order to broaden the scope of the project and secure a general applicability of the developed methodology, full-length tissue Factor (TF) and Ghrelin receptor (GHS-R1a) are selected as models of single-pass and multi-pass MRs. These MRs do not only display different topologies and functional assemblies but also different selectivity towards lipids. TF and GHS-R1a are central to blood coagulation and energy homeostasis, respectively, and also connected to genetic and metabolic disorders, and thereby not only relevant as model systems but also promising drug targets. The project will exploit the recent advances in SAXS/SANS- and NMR-based methods to study the TF and GHS-R1a in nanodiscs, with an emphasis on their conformational ensemble nature. Upon the establishment of the methodology, it will be extended to study the interaction with their endogenous ligands.;212194,8;212194,8;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;KOBENHAVNS UNIVERSITET;DK;;;;1;0;0;1;0;0 208569;745689;MELBA;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;MEMBRANE PROTEINS OF ELECTROACTIVE BACTERIA PROBED AT LIPID LAYERS ONTO MODIFIED ELECTRODES;2017-04-01;2019-07-22;;"MELBA aims at developing an efficient and versatile electrochemical platform for probing the charge transfer properties, electronic or protonic, of membrane proteins extracted from Gram negative electroactive bacteria. This 2 years research project will be conducted at the Université de Rennes 1, UR1 France, including a six months Secondment at Universidade Nova de Lisboa, UNL Portugal. Carbon electrodes will be covalently modified with pH-responsive electrophores through surface modification techniques, WP1 Task1. Lipid layers will be deposited onto the modified electrodes to create an artificial membrane as a host for extracted membrane proteins, WP1 Task2. The experienced researcher Dr. Leb?gue will learn protein expression, extraction, purification and characterization during the six months Secondment at UNL, WP2 Task3. Finally extracted proteins will be incorporated into the artificial membrane deposited onto the modified electrodes and their electronic and/or protonic charge transfer properties will be characterized, WP2 Task4. The ambition of MELBA is to understand the coupling of extracellular electron transfer with proton transport in Gram (-) electroactive bacteria. The outcome of MELBA will be useful to optimize potential microbial electrochemical technologies based on electroactive bacteria and will be applied to the characterization of the charge transfer properties of any membrane protein. Within MELBA, 3 oral communications will be given at international conferences, 5 high impact papers will be published in the field of bioelectrochemistry and 5 formal public engagement actions have been scheduled. MELBA will allow Dr. Leb?gue to develop and extend her expertise in electrochemistry, materials science and surface modification to microbiology and biochemistry. Dr. Leb?gue will enter the field of microbial electrochemistry and acquire a unique and solid interdisciplinary profile, required to compete for permanent academic positions and grants in Europe.";185076;185076;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;UNIVERSITE DE RENNES I;FR;;;;1;0;0;1;0;0 209566;747598;3DMUCHO;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Investigation of 3D Functional Connectivity in Mouse Visual Cortex using Holography and Optogenetics;2017-04-01;2019-03-31;;Cortical neurons respond selectively to sensory features. In mouse visual cortex, convergent evidences point towards stronger connectivity between neurons sharing similar feature selectivity in the superficial layers. The relationship between a three-dimensional (3D) subnetwork, where neurons connect horizontally and vertically to each other, and the functional specificity of individual neurons remain however unresolved. The main objective of this interdisciplinary project is to uncover the 3D functional connectivity in mouse visual cortex in vivo by employing the innovative optical methods pioneered in the host laboratory. Single-cell activation deep into the brain will be, for the first time, enabled using the novel technology of 3D depth-resolved holographic light-patterning and two-photon optogenetics. Combined with whole-cell recordings for measuring postsynaptic responses, precise presynaptic excitation with holography will permit mapping connection pairs within and across cortical planes. Simultaneous presynaptic multi-cell excitation of connecting neurons will test the integration linearity of the postsynaptic neuron. To probe functional connectivity, connection pairs will be examined from a functionally-identified neuronal population, whose tuning specificity to visual attributes is determined using calcium imaging. This fellowship will render me opportunities to acquire a versatile optical toolbox that is of general interest in neuroscience for connectivity mapping and circuit manipulation. Knowledge of local functional connectivity spanning a 3D cortical volume will further provide significant insights into the network mechanism underlying sensory processing.;173076;173076;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FR;;;;1;0;0;1;0;0 210351;754550;BITRECS;SIGNED;H2020-EU.1.3.4.;MSCA-COFUND-2016;H2020;Biomedicine international training research programme for excellent clinician-scientists;2017-10-01;2022-09-30;;"Significant advances in clinical practice cannot be made without a thorough understanding of the disease mechanisms from laboratory benches combined with good clinical observation and knowledge of disease management from the bed side. Clinician-scientists are the only professionals who can bridge these two worlds. The clinician-scientist role started decades ago within hospitals driven by the desire to understand and cure. However, a decrease in these vocations is now threatening progress and improvement of healthcare, thereby impacting on economic competiveness worldwide. IDIBAPS, the leading biomedical research institute of Hospital Clinic of Barcelona (Spain) as pioneer in fostering clinician scientists, proposes a 60-month innovative fellowship programme called BITRECS, Biomedicine international training research programme for excellent clinician-scientists, based on excellence only. Through 2 international peer-reviewed calls, it invites 10 fellows to implement a 36-month bottom-up research project through an outgoing phase (12-18 months at any worldwide institution outside Spain) and a return phase (18-24 months at IDIBAPS), helping to make a lasting impact within the European Research Area and put the European Union ahead of the game in this crucial area of human health. BITRECS is an international, intersectorial and interdisciplinary programme. This transnational mobility scheme will boost the fellows’ professional growth through: 1) continuous career support (scientific supervision, career mentoring and support for exploiting/disseminating the results); 2) participation in scientific and non-scientific training/networking activities linked to both sectors (academic and non-academic); and, 3) sharing experiences with peers from different disciplines. IDIBAPS, with its HRS4R strategy aligned to the European Charter and Code and a strong background in other human resources programmes guarantees a successful implementation.";2124000;1062000;H2020-MSCA-COFUND-2016;/MSCA-COFUND-FP;CONSORCI INSTITUT D'INVESTIGACIONS BIOMEDIQUES AUGUST PI I SUNYER;ES;;;;1;0;0;1;0;0 208687;750848;Art and Ethics;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Art and Ethics: Restarting and Advancing a Stalled Debate;2017-10-01;2019-09-30;;"This project is a work of philosophy that investigates how intrinsic ethical properties are realized in artworks and other aesthetic and creative objects and practices, and in what respects their aesthetic values are determined by these properties. The project innovates in three principal ways. First, it identifies and articulates novel ways by which artworks and similar objects and practices come to exhibit ethical properties, where the existing literature in this area relies exclusively on just one way this can occur. Second, it diagnoses why the literature on the question of ethico-aesthetic value interaction has stagnated for almost a decade, by revealing the vague and inconsistent conceptual tools on which its theorists have relied until now, and which have inhibited its progress. Finally, it uses the preceding two innovations to articulate a new and satisfactory theory about how ethical properties determine aesthetic values. The project promises to radically transform a live, if currently inert, philosophical literature while offering a comprehensive strategy to share its interdisciplinary and public interest benefits with stakeholders beyond philosophy and indeed the academy.";195454,8;195454,8;H2020-MSCA-IF-2016;/MSCA-IF-EF-RI;UNIVERSITY OF SOUTHAMPTON;UK;;;;1;0;0;1;0;0 209511;739891;Wearonics;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Developing Stretchable Conductive Fibres and their Implementations in Wearable Electronics;2017-04-01;2019-03-31;;Europe needs to take action to develop stretchable conductive materials to lead to the wearable electronics industry, which will be worth over $30 billion dollars in 2020. Although flexible electronics are dominating the current wearonics industry, their applications are restricted due to significant reduction in their conductivity under the applied strain. All stretchable conductors with mechanical compliance materials like human skin are required for epidermal electronic devices and wearable electronics. The ideal solution to this problem would be using a stretchable conductive material that can be woven into washable and breathable fabrics, which remains a significant challenge. To address this challenge, I have formulated an innovative and interdisciplinary strategy based on my research experience to develop stretchable conductive fibres (SCF) using silver nanowires and spandex fibre. After developing SCFs, I will bring together diverse academic and industrial experts to utilize SCFs in 4 different research environments. First, I will receive intensive training at the Wireless Communication and Research Lab to utilize SCFs in wireless communication and pervasive computing systems. Then, I will integrate these systems into the disabled friendly apparels at Universal Textile Centre. Finally, I will be seconded to two industrial organisations, ComfTech and Antelope, to create SCF based prototypes of Health Monitoring Systems and Electro Muscle Stimulation technologies. This fellowship will allow me to gain new expertise in multiple disciplines, and build complementary international partnerships between academia and industry, which will enable me to enhance my independence as a researcher in the wearonics field. The successful completion of this timely and innovative project will result in an advanced material that will contribute to the competitiveness of Europe in the wearonics field.;157845,6;157845,6;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;ISTANBUL TEKNIK UNIVERSITESI;TR;;;;1;0;0;1;0;0 208997;749973;SENSHOR;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;A Wearable Sensor for Hormones Based on a Native Microbial Sensing;2017-03-15;2020-03-14;;Connected devices that monitor human biology in real-time represent the next frontier in biosensors. Monitoring hormones is of significant interest as hormones play critical roles in multiple physiological processes including stress adaptation, blood pressure control, reproductive rhythms, and body odor. However, the real-time monitoring of hormones is challenging from a biology, chemistry, and engineering perspective, insulin detection being the one notable success. This project proposes to design a novel wearable device to sense estradiol (through sweat), a hormone responsible for fertility issues and mood disorders in women. This project is highly innovative and ambitious since it combines microbial genetics and protein identification, new polymer and nanoparticles compositions, and a novel sensor design. The wearable device (i.e., bracelet) will contain an optical-to-electrical interface for recording the fluorescence output of a biosensor, based on estradiol sensitive transcription factor isolated from a microbial organism. The biosensor is composed of biopolymers functionalized with fluorescent reporters and a hormone-sensitive transcription factor. Without the hormone, the two fluorescent entities are off, while in the presence of estradiol, an optical signal is emitted. The project will be conducted in two international prestigious laboratories in France and in the USA to give to the applicant the best interdisciplinary scientific environment, and ensure the ultimate success of this project. The applicant will be the main spokesperson and lead investigator of the project. This international exposure and this fellowship will provide the applicant a unique and multidisciplinary profile, while facilitating her future academic career as a researcher in France.;264668,4;264668,4;H2020-MSCA-IF-2016;/MSCA-IF-GF;UNIVERSITE DE BORDEAUX;FR;;;;1;0;0;1;0;0 208673;749815;XeMoon;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Sources and sinks for excess Xe and Ar on the Moon;2018-05-01;2020-04-30;;Noble gases trace the evolution of reservoirs inside terrestrial planetary bodies because their isotopic signatures are diagnostic of volatile sources. In addition, original compositions can be modified by radioactive decay of rock forming elements, providing constraints on the chemistry of an interior reservoir and the time at which it was isolated (since when noble gases were retained). Some lunar samples are known to preserve signatures in xenon and argon that were degassed from one or more interior sources to the exosphere, then incorporated into the regolith, potentially allowing this record to be read. In this work I will combine (i) my expertise in lunar evolution, sample characterization and the 40Ar-39Ar system, (ii) the University of Manchester’s expertise in xenon isotope systematics, world-leading instrumentation for xenon isotopic analysis and state-of-the-art sample characterisation facilities, and (iii) expertise relevant to the lunar exosphere from a network of collaborators. With this team, I will (i) determine the range of xenon and argon signatures in lunar regolith samples and the times at which they were incorporated, (ii) develop a model of the lunar exosphere to infer source reservoir compositions from those measured in samples and so (iii) investigate the number of contributing lunar reservoirs, their compositions and their histories. The results of this interdisciplinary study will be disseminated to the range of specialist and non-specialist audiences. They will serve to test models of lunar evolution, allow comparison with the Earth and Mars to gain wider understanding of terrestrial planetary bodies, and stimulate engagement with planetary science. Additionally, I will develop my leadership and teaching skills by completing the University of Manchester’s New Academics Programme, equipping me to move to the next stage of my career as a researcher, leader and teacher for the next generation of multidisciplinary planetary scientists.;183454,8;183454,8;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;THE UNIVERSITY OF MANCHESTER;UK;;;;1;0;0;1;0;0 209781;748066;MILO;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Mining, lobbying and efficient environmental policy;2017-12-01;2019-12-28;;Natural resources including raw materials are important for the European Union since they are a part of the base of the economy and simultaneously a large pollution and waste source. Sustainable development of the mining sector extracting the raw materials calls for an economic analysis of environmental policy, which is the central theme of the MILO-project. The objective of the project is to investigate the optimal environmental policy of the mining sector with a special emphasis on mining specific features and the choice of policy instruments under lobbying. Through its research results obtained using dynamic optimization methods, game theory and an array of dissemination and communication efforts, the project will help to improve the currently applied policies in Europe. In addition to policy advice, the project will result in new insights on the formation of lobby groups and policy instruments by combining two game theoretical approaches, namely, the common agency framework and coalition theory modeling. The researcher, who is trained in the theory of environmental policy instruments and dynamic optimization methods, will conduct the research and training in FEEM’s international and interdisciplinary working environment and will be supervised by an expert in the research field. The project with its trainings improves his research and transferable skills, and extends his international networks through the host’s contacts and through a research visit. By including versatile training-through-research, multiple dissemination and communication methods, public engagement through the MILO-webpage and blog, and networking the project has a strong impact on the researcher’s career, on the future research collaboration as well as on the public interest.;180277,2;180277,2;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;UNIVERSITA CA' FOSCARI VENEZIA;IT;FONDAZIONE ENI ENRICO MATTEI;IT;;1;0;0;1;0;0 209352;751277;DEBBIE;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;A database of experimental biomaterials and their biological effect;2018-09-01;2020-08-31;;The advent of material science and manufacturing techniques in the last century has led to the development of thousands of novel biomaterials, with potential to revolutionise health care. However, the vast majority of biomaterial studies do not progress beyond the stages of design and testing, and therefore a substantial amount of scientific data is only available in the form of research publications. To date, there is no database curating the experimental data generated by testing novel biomaterials in vitro and in vivo, representing a loss of a valuable big (experimental) data. In here, we propose an open-access database of experimental tissue scaffolds, indexing design features, cellular and tissue responses, thus creating an exhaustive inventory of experimental scaffolds. Such a dataset would enable scientists to efficiently search and interpret relevant information from past studies across all tissues and models, as well as create computational tools to predict and optimise cell-material interaction. A comprehensive map of research activity and findings should also make it easier to identify areas where data is missing or lacking. A systematic, up-to-date overview of the field will also be a useful tool for science policy making. The novelty of the project lies not only in the concept of curating data from laboratory evaluation of experimental biomaterials (rather than just approved medical implants), but also in attempting to face the methodological challenge of extracting and structuring information from the heterogeneous and vast field of experimental biomaterials. One of the keys of this interdisciplinary project is crowd-sourcing biomaterial scientists, thus engaging their expertise and understanding their needs, in order to create a comprehensive, relevant and useful tool to enhance research in the field.;170121,6;170121,6;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;UNIVERSITAT POLITECNICA DE CATALUNYA;ES;;;;1;0;0;1;0;0 209374;752292;SLLB;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Sacred Landscapes in Late Byzantium;2018-02-01;2020-01-31;;"This interdisciplinary project will explore texts composed by the fourteenth-century Constantinopolitan Patriarch Philotheos Kokkinos, with a threefold focus on: 1. The creation of sacred landscape in fourteenth-century Byzantium. 2. The attitude(s) towards and representation(s) of women in late Byzantine patriarchal society. 3. The textual transmission of Kokkinos’ saints’ lives. The project includes the preparation of critical editions for two hitherto unedited hagiographical texts written by Kokkinos. The fellow will receive training in digital humanities and textual criticism which will further his career goal of becoming a lecturer in Medieval Studies. This research project will contribute to a better understanding of Eastern medieval thought-worlds, particularly during the troubled period of the fourteenth century, which saw a shrunken Byzantium struggle for survival between the growing Muslim East and the Latin West.";195454,8;195454,8;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;UNIVERSITY OF NEWCASTLE UPON TYNE;UK;;;;1;0;0;1;0;0 208613;747464;DENOCS;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;The Double Edged Role of Nitric Oxide and Hydrogen Peroxide in a Coral Symbiosis;2017-06-01;2019-05-31;;"Global climate changes affect coral reefs worldwide and these valuable marine biodiversity hotspots are increasingly experiencing a symbiotic dysfunction known as coral bleaching, where the global bleaching events in 2016 are the most significant to date. The underlying physiological mechanisms inducing the bleaching response remain unclear. It is known that cellular oxidative stress and reactive species such as nitric oxide (NO) and hydrogen peroxide (H2O2) are involved, but the sources and sinks of these compounds, their interplay and spatio-temporal dynamics have not been investigated in corals, partly due to lack of suitable experimental tools. The DENOCS projects will apply a suite of novel quantitative assessment techniques to investigate the dynamics and impact sites of NO and H2O2 in intact corals, coral tissue culture, and isolated photosymbionts when subjected to experimental treatments mimicking global change-induced environmental stress scenarios. This will encompass expert training of Dr. Schrameyer in the use of novel microsensors for NO and H2O2 in combination with advanced bioimaging of the oxidative and nitrosative stress response in corals, variable chlorophyll fluorescence imaging and cellular 14C-fixation assays to assess symbiont photosynthesis. Prospective outcomes of DENOCS include a better understanding of oxidative and nitrosative stress responses in corals, quantification of threshold concentrations and impact sites of reactive oxygen and nitrogen species, and how these are involved in the coral bleaching response. The project DENOCS will promote EU’s research and innovation excellence through its interdisciplinary measurement approach and international collaboration, and will enable the restart of a promising career of Dr. Schrameyer after a maternity break.";212194,8;212194,8;H2020-MSCA-IF-2016;/MSCA-IF-EF-CAR;KOBENHAVNS UNIVERSITET;DK;;;;1;0;0;1;0;0 208910;747030;MedRoute;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;On the route of multiculturalism(s). Marking and hybridizing identities in the late 17th and early 18th centuries Mediterranean port cities;2017-09-01;2020-08-31;;"This project aims to analyze the phenomenon of multiculturalism in four Mediterranean port cities of the late seventeenth and the early eighteenth centuries. The research uses three identity markers (foodways, clothing, and language) to chart how differences in the political and physical environments affect the balance between marking and hybridizing identities in the port cities of Izmir, La Valletta, Livorno and Marseille. Although very different amongst themselves, these four cities, placed on a maritime trading route cutting the Mediterranean from east to west, share a highly developed cultural, ethnical, and religious pluralism. The comparative analysis adopted will shed light on the concept of multiculturalism(s) in the pre-modern Euro-Mediterranean space, explaining how members of the same group handled coexistence following different strategies. In analyzing identity as a dynamic process, the research enters into the historiographical debate on the One-Plural nature of the Mediterranean on two critical levels: the ways in which Mediterranean identities interact with one another and how they generate a multicultural zone. Through an interdisciplinary study, the project will shape the ineradicable ambiguous nature of multicultural zones in the Mediterranean. This goal will be undertaken through the analysis and verification of three main assumptions that form the basis of the research: 1. The role of the political factor in determining the type of multiculturalism which developed and the ethical role of politics in assuming tolerance as a tool for fostering a more vibrant and resourceful society. 2. The role played by internal members of the communities on the basis of social class, education and gender, and how these factors determined the individual positioning on the scale from integration to segregation. 3. The functionality of multicultural policies in enhancing urban welfare.";244269;244269;H2020-MSCA-IF-2016;/MSCA-IF-GF;CONSIGLIO NAZIONALE DELLE RICERCHE;IT;;;;1;0;0;1;0;0 209476;715874;FLIGHT;SIGNED;H2020-EU.1.1.;ERC-2016-STG;H2020;The true costs of bird flight: From the laboratory to the field;2017-04-01;2022-03-31;;Flight is thought to be one of the most energetically costly of bird activities. These costs matter by virtue of their magnitude, as factors affecting flight costs can have a disproportionate impact on the overall energy balance. Flight costs are fundamentally linked to airflows, as well as behavioural responses to them, because birds react to horizontal and vertical currents by changing flight mode (i.e. flapping/ gliding), speed and route. Even minor route adjustments can radically affect the flow conditions that birds experience due to the uniquely dynamic and heterogeneous nature of the aerial environment. Yet our understanding of how airflows impact birds is in its infancy, being constrained by a lack of information on the metabolic costs of flight. Currently, the main methods for measuring flight costs in the laboratory either restrain the bird (thereby increasing energy expenditure) or suffer from low resolution, and field methods do not allow costs to be resolved in relation to fine scale movement paths. FLIGHT will use interdisciplinary approaches, integrating laboratory and field techniques, to address these grand challenges. Breakthrough methodologies will be used to (1) measure the costs of unrestrained bird flight in the laboratory and (2) derive a new proxy for power use in flight that is linked to flight performance, using accelerometry measurements from cutting-edge data loggers. Loggers will then be (3) deployed on wild birds to quantify their responses to airflows and the energetic consequences over fine scales. This will provide completely novel, mechanistic insight into the way the physical environment impacts flight costs, and (4) enable variation in flight–related energy expenditure to be modelled geographically and seasonally in model species. Overall, FLIGHT will provide new macro-ecological insight into relationships between bird distributions and flow conditions and inform assessments of how birds may be affected by changing wind regimes.;1996042,5;1996042,5;ERC-2016-STG;/ERC-STG;SWANSEA UNIVERSITY;UK;;;;1;0;0;1;0;0 209620;750528;funcSOFI-PD;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Quantitative super-resolution optical fluctuation and phase microscopy for structural and functional imaging of Parkinson's disease;2017-04-01;2019-03-31;;The changing demographic is one of the greatest challenges in Europe. With an expected 25% of the population over 65 by 2030, the incidence of neurodegenerative age-linked diseases like Alzheimer’s and Parkinson’s is likely to increase. They severely impact quality of life and to date, therapies can only treat the symptoms. Oligomerization and aggregation of the protein ?-synuclein is a hallmark of Parkinson’s disease. Still, the underlying molecular mechanism of cellular dysfunction due to toxic forms of this protein remains unclear. Most studies aiming to uncover ?-synuclein induced neurodegeneration in vivo are using indirect biochemical detection methods. Bridging neurobiology and life science with advanced microscopy and image analysis allows the direct monitoring of Parkinson compromised primary hippocampal neurons. I will combine multi-color 3D super-resolution optical fluctuation imaging with quantitative phase tomography in a multi-plane microscope, to allow structural and fast functional imaging. This innovative imaging concept is used (1) to elucidate ?-synuclein aggregation at the cell membrane and in the cytosol and (2) to uncover the induced cytoskeleton alterations. Ultimately, molecule-specific readout will be complemented by (3) label-free, quantitative phase imaging of membrane dynamics and overall cell morphology at up to 100Hz. I am a biophysicist with a specialization in single molecule spectroscopy and my previous work on photon statistics has led to several high quality publications. This fellowship expands my quantitative microscopy expertise to 3D imaging while enlarging my biologocal scope to neurodegenerative diseases. I will extend my competences by managing the project, following complementary skills courses, and organizing public outreach activities. While performing interdisciplinary research on neurodegenerative disease, I will develop an independent research profile to further enhance the European research landscape.;175419,6;175419,6;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE;CH;;;;1;0;0;1;0;0 209680;753527;EpiPur;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;The ATP-P2X7R axis: a target for drug-refractory epilepsy;2018-01-01;2019-12-31;;"Current epilepsy therapies, based on mediating excitation or inhibition have no impact on disease progression and are ineffective in over 30% of patients, demonstrating the urgent need for therapies with different mechanisms of action. An exciting concept is that increased hyperexcitability states and network changes are caused and maintained by a sustained glial activation.The ATP-gated P2X7 receptor (P2X7R), a gatekeeper of inflammation, has recently emerged as a promising target for epilepsy, showing anticonvulsant and disease-modifying properties in animal models. To bring P2X7R further towards a clinical application, however, important gaps in our understanding must be filled. Evidence for ATP release in the brain during seizures is currently lacking, the cell types involved in pathological P2X7R activation must be determined, and whether results from rodent models can be replicated in human tissue must be tested. Recent technical advances now bring the answers to these questions within reach. EpiPur brings together a team of experts in purinergic signalling, industrial partners specialised in the development of P2X7R antagonists and epilepsy clinicians. Biosensors will be used to record ATP in vivo with high sensitivity and temporal resolution; new transgenic mouse lines will be used to elucidate the subcellular expression and cell-specific disease contribution of P2X7R. Newly developed P2X7R antagonists will be tested in brain tissue resected from epilepsy patients. This highly interdisciplinary and intersectoral approach will add a significant contribution to the understanding of neuroinflammatory processes in disorders of the CNS. Further, the skills acquired during the research project, the excellent training record of the supervisor and host institution and the outstanding resources for learning and development available at RCSI will give me the tools necessary to achieve research independence.";175866;175866;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;ROYAL COLLEGE OF SURGEONS IN IRELAND;IE;;;;1;0;0;1;0;0 208654;749188;IDENTITIES;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Integrative Approaches to Dental Wear: Non-Masticatory Tooth-Use Across the Mesolithic-Neolithic Transition Among Iberian Foraging and Farming Societies;2017-10-01;2019-12-31;;The IDENTITIES project investigates human dental wear related to the non-masticatory use of the dentition (the habitual use of “teeth-as-tools”) among human groups that span the Mesolithic-Neolithic Transition in the Iberian Peninsula – a period of complex social, economic, and technological reorganization corresponding to a shift from hunting and gathering to a dependence on domesticated plants and animals. A lifetime of using the teeth for habitual, manipulative tasks leaves distinct traces on enamel, and these idiosyncratic patterns of wear provide biocultural markers of social identities when aligned with information on sex, age, occupation, or status of individuals across archaeological samples. Human dental remains from archaeological sites across the Iberia provide an ideal regional focus for exploring biocultural changes related to tooth-use during a crucial prehistoric socioeconomic transition. IDENTITIES is interdisciplinary, bringing together experts in microscopy, experimental methods, bio/archaeology, and paleoanthropology through an integrative methodology to document non-masticatory dental wear. The methodologies include recent advances in Gigapixel-like imaging strategies, confocal and scanning electron microscopy, and three-dimensional dental topographic methods to analyze experimentally-worn and archaeological samples. The integrative methodology was also established to cross-validate each method (presently an unresolved issue), and advance the study of material surface modification of biological and archaeological materials generally. In addition to providing an intellectual impact through methodological advances, the same data will directly address how biocultural changes in non-masticatory tooth-use reflect changing social identities across archaeological groups of the last foraging peoples (Mesolithic), nascent farming societies (Neolithic), and established agriculturalists (Chalcolithic) in the Iberian Peninsula.;158121,6;158121,6;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;FUNDACIO PRIVADA INSTITUT CATALA DE PALEOECOLOGIA HUMANA I EVOLUCIO SOCIAL;ES;;;;1;0;0;1;0;0 209490;724951;SENSIS;SIGNED;H2020-EU.1.1.;ERC-2016-COG;H2020;The Senses of Islam: A Cultural History of Perception in the Muslim World;2017-09-01;2022-08-31;;"The aim of SENSIS is to write a cultural history of the senses in Islam, by examining how the senses have been conceptualised, and calibrated, in a variety of Muslim environments. Sensory perception is not only a physical but also a cultural act: how people experience and understand sight, sound, smell, taste, and touch differs according to the historical, geographical, social and intellectual contexts in which perception occurs. Accordingly, this project comprehensively studies the Muslim sensorium, past and present. The topic is timely and important because (1) questions relating to the sensorium inform, and often complicate, intercultural encounters as well as inner-Muslim debates over identity and alterity; (2) there is a critical need to examine the scholarly contention that Islam’s alleged denigration of vision undermines its ability to modernise; and (3) the hackneyed notion that Islam celebrates the senses, as opposed to a disembodied, rationalised West, is likewise in need of a thorough revision. No sustained, comprehensive reflection on these issues exists in current scholarship, whether in historical-critical, text-based Islamic Studies, the field of study in which this project is primarily located, or in any of its cognate disciplines. Researchers in SENSIS (PI, 2 postdocs, 2 PhDs) will study the topic diachronically through the centuries as well as synchronically across diverse traditions of thought in Islam (in five subprojects: epistemology, mysticism, ethics, law, and aesthetics), thereby avoiding a monolithic, essentialising account of Islam’s attitude toward the senses. The project combines textual approaches in Islamic Studies with methods and theories from religious studies, anthropology, and the emerging field of sensory history. Additional financial support is solicited to facilitate five interdisciplinary workshops, each devoted to a sense organ, as well as a concluding, synaesthetic conference on the senses in Islam.";2000000;2000000;ERC-2016-COG;/ERC-COG;UNIVERSITEIT UTRECHT;NL;;;;1;0;0;1;0;0 209706;715423;BRASILIAE;SIGNED;H2020-EU.1.1.;ERC-2016-STG;H2020;Indigenous Knowledge in the Making of Science: Historia Naturalis Brasiliae (1648);2018-01-01;2022-12-31;;"This project is an interdisciplinary study of the role of indigenous knowledge in the making of science. Situated at the intersection of history and anthropology, its main research objective is to understand the transformation of information and practices of South American indigenous peoples into a body of knowledge that became part of the Western scholarly canon. It aims to explore, by means of a distinctive case-study, how European science is constructed in intercultural settings. This project takes the book Historia Naturalis Brasiliae (HNB), published in 1648 by Piso and Marcgraf, as its central focus. The HNB is the first product of the encounter between early modern European scholarship and South American indigenous knowledge. In an encyclopedic format, it brings together information about the natural world, linguistics, and geography of South America as understood and experienced by indigenous peoples as well as enslaved Africans. Its method of construction embodies the intercultural connections that shaped practices of knowledge production in colonial settings across the globe, and is the earliest example of such in South America. With my research team, I will investigate how indigenous knowledge was appropriated and transformed into European science by focusing on ethnobotanics, ethnozoology, and indigenous material culture. Since the HNB and its associated materials are kept in European museums and archives, this project is timely and relevant in light of the growing concern for the democratization of heritage. The current debate about the societal role of publicly-funded cultural institutions across Europe argues for the importance of multi-vocality in cultural and political processes. This project proposes a more inclusive interpretation and use of the materials in these institutions and thereby sets an example of how European heritage institutions can use their historical collections to reconnect the past with present-day societal concerns.";1475565;1475565;ERC-2016-STG;/ERC-STG;UNIVERSITEIT LEIDEN;NL;;;;1;0;0;1;0;0 209026;750969;Womenswriting;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Women’s Plague Writing in Early Modern England;2017-09-01;2020-08-31;;In a time when high-profile outbreaks such as zika and ebola frequently make news headlines, the proposed research project, ‘Women’s Plague Writing in Early Modern England’, provides an opportunity to interrogate how we interpret medical writing, who talks about medical problems and how gender becomes entangled in outbreaks by looking to the past. ‘Women’s Plague Writing in Early Modern England’ will undertake a survey and analysis of women’s plague writing in England from 1550 to 1700. A three-year Global Fellowship project with a two-year outgoing phase at the University of Toronto (UofT) and incoming phase at Queen’s University Belfast (QUB), the research action takes an interdisciplinary approach to women’s plague writing across the early modern period in England. The research programme explores the medical humanities through the lens of literature in its historical context. This project will change the canon of plague writing, which has hitherto focused on male-authored texts. Moving from the single outbreak focus seen in my first monograph, The Literary Culture of Plague in Early Modern England (forthcoming with Palgrave Macmillan), the outcome of the project makes the significant leap to studying a period of plague writing, a bigger-scale picture, with a broad chronology that captures major plague outbreaks in 1592, 1603, 1625, 1630, 1636 and 1665. The project encapsulates a full-period picture of women’s interactions with plague and medicine and the corresponding gendering of plague writing. It will examine how women discuss the disease and how this differs from male-authored texts. It will ask how the medium chosen for publishing a text, print or manuscript, impacted how women discussed the disease. It will investigate how women’s understanding of plague was gendered and, more broadly, how the textual construction of pestilence was gendered in early modern England.;255349,8;255349,8;H2020-MSCA-IF-2016;/MSCA-IF-GF;THE QUEEN'S UNIVERSITY OF BELFAST;UK;;;;1;0;0;1;0;0 208661;749232;AMAM;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Ageing Multiphysics of Asphalt Materials;2017-09-21;2019-09-20;;The ultimate objective of this fellowship, entitled “Ageing Multiphysics of Asphalt Materials (AMAM)”, is to intensively train a talented researcher, Dr Fan Gu, through an interdisciplinary project focused on the modelling of the ageing multiphysics and performance evaluation of asphalt materials. Deliverables including fundamental understanding of asphalt ageing multiphysics, novel anti-ageing materials and a systematic performance prediction framework for engineering applications in sustainable design, construction, and maintenance of road infrastructures. The Fellow will receive intensive technical training in multidisciplinary field of chemistry (Aston), material science (Aston), computational modelling (Aston, TUD), experimental characterisation (NTEC) and industry applications (Nynas and AI). The Fellow will also receive inter-sector professional skills training in project management, organization and networking. The project outputs will enhance the EU scientific excellence by exploring the ageing mechanisms of complex bitumen-based materials, strength the EU industry leadership in anti-ageing material innovation, and protect EU environment and natural resources through extended service life of the aged road infrastructures using innovated recycled/bio-based anti-ageing construction materials. Uniquely, the project will enable the Fellow to an independent leading researcher in infrastructure engineering for his academic career and to become a rare asset to European research through leading the research and building effective collaboration network among academia and industry.;195454,8;195454,8;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;ASTON UNIVERSITY;UK;;;;1;0;0;1;0;0 209395;753112;AcTaferon;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Revitalizing the clinical potential of type I IFNs in fighting influenza A virus infections with AcTaferon.;2017-05-01;2018-12-31;;Based on their antiviral and antitumor effect, type I interferons (IFNs) were believed to be the miracle drug to tackle viruses and cancer. However, clinical IFN applications remained limited due to severe side effects resulting from widespread cellular sensitivity to IFN, which limits the administrable doses. Hence, the drug concentration at the desired infection or tumor site is often too low to be fully therapeutic efficient. AcTaferon (Activated-by-Targeting interferon), co-developed by Prof. Uzé, circumvents these obstacles. By fusing an IFN mutant with strongly reduced receptor binding affinity to a targeting moiety that recognizes a surface marker on specific cells, AcTaferon remains inactive “en route” through the body and unveils its biological activity only on specific target cells. Robust tumor regression without side effects and preliminary antiviral effects underscore the huge clinical potential of AcTaferon to fight cancer and viral diseases. By combining the AcTaferon and influenza expertise of Prof. Uzé and Prof. Saelens, respectively, this interdisciplinary project offers the opportunity to broaden the innovative AcTaferon therapeutic strategy from the cancer to the viral infection field. Influenza A was selected as a pilot target as seasonal influenza A epidemics and occasional pandemics remain a serious health threat causing substantial morbidity and mortality. Influenza A-targeted AcTaferons will be developed and analyzed in relevant in vitro and in vivo models. Eventually, all knowledge will be transferred to Orionis, a company that will implement the AcTaferon technology to develop novel drugs. My background on the intracellular processes that negatively regulate cytokine receptors and hence influence the cellular sensitivity to a (therapeutic) cytokine is an asset to this project. I will be able to extend my fundamental research experience with applied cytokine research, which may extend into a new academic or industrial research pipeline.;144230;144230;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FR;;;;1;0;0;1;0;0 209312;749889;TIMEGG;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;TIMING FERTILIY- A Comparative Analysis of Time Constructions and the Social Practice of Egg-Freezing in Germany and Israel;2018-02-01;2020-01-31;;"'Technological advancements in reproductive medicine have introduced the new concept of 'FREEZING'. Nowadays, healthy women are given the possibility to cryopreserve their oocytes in order to prolong their fertility, a procedure known as 'social egg freezing'. There is an ongoing bioethical academic and public debate on the social and ethical implications of this practice. The here proposed socio-empirical research is interested in extending our understanding of the concept of 'freezing' in broader contexts, while analyzing it through the prism of 'sociology of time'. Egg freezing constitutes an extremely fascinating paradigm for studying concepts of time, timing, planning and its social-technological manipulation related to modern life science. In line with the IF work program's focus on creativity, innovation and diversity, this research aims to examine the interplay of culture and bioethics in an interdisciplinary and empirical manner, focusing on and comparing experts' and lay positions and using a cross-cultural German-Israeli comparative research framework. This cross-cultural comparison is especially interesting since the German regulatory and legal framework regarding new reproductive technologies is rather restrictive, while the Israeli regulation has been identified as extremely permissive. Using qualitative in depth interviews with relevant experts as well as users of social egg freeing, this research aims at (a) In-depth empirical analysis of time in the context of reproductive medicine; (b) A cross sectional analysis of social egg freezing by comparing two national contexts as well as experts and ordinary (lay) ethics; and (c) Theorization of the time dimension for the relationship of reproduction, labor and gender. Thus, this innovative research is expected to enhance the researcher academic competence and the transfer of new knowledge.'";171460,8;171460,8;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;UNIVERSITAETSMEDIZIN GOETTINGEN - GEORG-AUGUST-UNIVERSITAET GOETTINGEN - STIFTUNG OEFFENTLICHEN RECHTS;DE;;;;1;0;0;1;0;0 209284;748459;DELICE;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Device oriented molecular spin filter based interfaces;2017-09-01;2019-08-31;;We live in a constantly changing society in which information and communication are at the basis of our economy. To keep progressing is essential to investigate new feasible ways to control and manipulate information in order to develop faster, smaller and less consuming devices. Organic Spintronics has emerged as a promising field to develop low-cost, mechanically-flexible and multi-functional devices in which information is carried not only by the charge but also by the spin of electrons. However, the injection and transport of the spin information through a device remains challenging, being organic/inorganic interfaces key to overcome this limitation. DELICE addresses the interface engineering in organic spintronics, aiming to profit from unique molecular capabilities for the development of highly performant chemically-tailored organic spintronic devices. In particular, DELICE focuses on exploiting the predicted spin filtering behavior of some organometallic molecules to obtain highly spin-polarized interfaces, enhancing the spin injection from ferromagnetic surface or even creating spin-polarization on non-magnetic metal surfaces. These so-called spinterfaces will be implemented in organic spintronic devices, spin valves, in order to determine the impact they have on the device performances. While organics have been mainly used as passive spacers in such devices, DELICE plans to go beyond the state of the art by actively exploiting the molecule’s spin filtering capability to improve device performances. A thorough characterization of the spinterfaces properties together with their implementation in real devices will provide us with valuable knowledge about the role of interfaces in devices. The technological potential of such a result represents a major step towards the realization of competitive organic nanodevices. The ultimate goal of DELICE is offering an interdisciplinary training to a promising young female researcher.;170121,6;170121,6;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;Asociacion - Centro de Investigacion Cooperativa en Nanociencias - CIC NANOGUNE;ES;;;;1;0;0;1;0;0 208853;743569;AFRI-SKYFOR;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;African Sky Forests: services, threats and management recommendations;2017-08-01;2020-07-31;;"Tropical montane forests (TMF) are biodiversity rich and unique ecosystems which provide water to tens of millions of people, among other services such as firewood, medicinal plants, hazard prevention, climate modulation and carbon sequestration. However, TMF remains understudied and over-exploited, particularly in Africa. Predicted climatic changes and trends in population growth will negatively affect the ecological functioning and ecosystem service delivery of these already fragile ecosystems. Therefore, there is an urgent need to better understand these ecosystems and use that information to inform management. AFRI-SKYFOR, focused on TMF in Africa, will provide new information key for understanding and improving the management of these ecosystems. I will combine data on multiple ecosystem services (e.g. water, medicinal plants, carbon), ecosystem threat, environmental and socio-economic data, modelling and novel state-of-the-art methodologies (such as socio-ecological ecosystem modelling using Bayesian statistics) from the fields of ecology, conservation science and ecosystem valuation to (1) identify and prioritize the ecosystem services generated by African TMF; (2) assess current and future threat presence and severity to these ecosystems; (3) create a model of the socio-ecological functioning of African TMF and simulate potential future scenarios; and (4) develop management recommendations for future sustainability. AFRI-SKYFOR is a highly interdisciplinary project which will generate information of wide relevance for the sustainable use of natural resources in African mountains. The high scientific quality and applicability proposed will benefit the EU not only by generating new knowledge and publications in high-profile scientific journals which will contribute to the enhancement of EU scientific excellence, but also by contributing to EU commitments within International treaties such as the Aichi Biodiversity targets and the Sustainable Development Goals";251857,8;251857,8;H2020-MSCA-IF-2016;/MSCA-IF-GF;UNIVERSITY OF YORK;UK;;;;1;0;0;1;0;0 210336;753903;SMArtPlate;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;A ductile, high energy absorptive and rapid post-tensioning system for extending life of concrete structures;2017-12-01;2019-11-30;;Extending the service life of reinforced concrete structures not only represents an economical advantage to owners, but also significantly contributes to the sustainability of the built environment, through the saving of natural resources and reduction of green gas emissions. In view of the shortcomings of the most commonly used strengthening techniques, such as FRP systems, the state of the structural retrofitting art demands a robust retrofitting solution feasible of rapid installation and easy post-tensioning applications along with a high energy dissipation capacity (e.g. independently of the quality and thickness of concrete cover, no need of mechanical devices for the post-tensioning applications and an adhesive free connection system) for specific cases such an strengthening against earthquake, impact and blast due to either accidents or terrorist attacks. This product-oriented proposal aims to develop an innovative element, herein after designated SMArtPlate to meet these requirements. Such a thin prefabricated plate will be precisely tailored to utilize the synergistic advantages of two advanced materials for the retrofitting of RC structures: ductile fiber reinforced geopolymer mortar and shape memory alloys (SMA). Following an interdisciplinary approach, experimental and numerical investigations will be conducted to develop and assess strengthening performance of the SMArtPlate.;183454,8;183454,8;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;THE QUEEN'S UNIVERSITY OF BELFAST;UK;;;;1;0;0;1;0;0 209060;752619;METABOLON;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Molecular understanding of metabolic complexes: Towards engineering the next generation of synthetic biosystems;2018-09-01;2020-08-31;;"Why most plant natural products escape industrial production? So far, synthesis of many of these high-value compounds in microbes is simply based on putting together all the players in a pathway. Nevertheless, to produce its stunning chemical diversity, nature uses much more elaborate biosynthetic networks, frequently involving the formation of macromolecular assemblies termed metabolons. These complexes utilize dynamic interactions and partner exchange to produce the desired compounds in a coordinated fashion. To take my biotechnological expertise one step further, I will study the dynamic mechanisms that rule the assembly and regulation of metabolons and use this knowledge to reshape the way microbial production platforms are engineered. METABOLON clearly introduces a new level of analysis and intervention into metabolic engineering, by examining the efficiency of complex formation and the fine molecular details that could affect enzyme performance. In addition, it develops tools and methods to obtain a molecular understanding of the role of the host membranes in heterologous enzyme function. Importantly, it introduces the concept of altering the host environment to mimic that of the native pathway host, and suggests approaches to achieve this in the case of the ER membrane. With a pressing need to move towards a bio-based society (H2020 priorities), METABOLON will set the blueprint for the rational engineering of the many complexes that create a plethora of bioactive compounds, natural aromas, flavours and colours. METABOLON will help me immensely to develop a unique skill-set that brings together my previous expertise in metabolic engineering with newly acquired knowledge in enzymology, single-molecule microscopy and biophysics. This will enable me to develop an interdisciplinary research program and pursue an independent academic career in the highly demanding field of synthetic biology.";212194,8;212194,8;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;KOBENHAVNS UNIVERSITET;DK;;;;1;0;0;1;0;0 208728;752896;PaCDoC;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Electric field driven propulsion and collective dynamics of homogeneous and patchy colloidal capsules.;2017-04-01;2019-03-31;;"Colloidal capsules are interesting from the point of view of both physics and application. They can be used for controlled material transport and targeted release, and they have shown tremendous potential for fabricating advanced materials through self-assembly. Recently, such capsules have also been able to propel in carrier fluid by methods including magnetic fields, thermal gradients and bubble propulsion mechanisms. Building on former research by the Experienced Researcher and the main supervisor, as well as new areas of expertise, this project will develop novel fabrication routes for microcapsules with and without functionalised shells (patchy capsules) and propel them over milimeter distances using external fields. The main objective of this action is to experimentally demonstrate propulsion of microcapsules via novel methods involving anisotropic electrodeformation and electrorotation. The experimental research will fill the missing gap in the field of propelling capsules, now mostly presented by computational and theoretical work. There are many examples of collective phenomena in nature, ranging from swarming bacteria colonies to flocking animals, and much attention has been devoted to understanding and imitating their collective properties and behaviour. The research project will give the first experimental realisation of collective capsule dynamics by propelling hundreds of electrorotating capsules at boundaries. Such a system has enormous potential for future technology and will be helpful in many aspects, for example, to lower human infertility, design microrobots for drug delivery, biodegradation of environmental pollutants and control of material properties. This proposal includes both the training of the candidate and a two-way transfer of knowledge with the host institution and partner organisations. The interdisciplinary aspect of the action is strong, involving a combination of soft-matter physics, medicine, engineering and applied sciences.";134462,4;134462,4;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;UNIWERSYTET IM. ADAMA MICKIEWICZA W POZNANIU;PL;;;;1;0;0;1;0;0 208919;747297;QAPs;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;G-Quadruplex-associated proteins (QAPs) and their role in transcriptional regulation;2017-04-01;2019-03-31;;"In the human genome, many G-rich sequences have the potential to form 4-stranded non-canonical secondary structures known as G-quadruplexes (G4s). G4 structures have been visualized in nuclei by immunofluorescence and mapped genome-wide to regulatory chromatin regions linked to elevated transcription using G4 chromatin immunoprecipitation and high-throughput sequencing (G4 ChIP-seq). G4s are implicated in gene regulation, DNA replication and genome instability, yet little is known about their protein interaction partners or role in regulating genome activity. We therefore propose to develop G4 Rapid Immunoprecipitation Mass Spectrometry of Endogenous Proteins (G4 RIME) methodologies to elucidate the G4 interactome within a native chromatin context. ChIP-seq of protein candidates coupled with G4 ChIP-seq will verify binding at endogenous G4 structures. Using established biophysical and biochemical techniques, we will investigate binding modes, recruitment and effects on G4 dynamics. Consecutive chromatin immunoprecipitation steps using antibodies targeting characteristic chromatin marks as well as G4 ChIP-seq supported by bioinformatics analysis of genomic databases will identify proteins involved in transcriptional regulation. We will then test the consequence of stabilising G4s with small molecule ligands on the G4 interactome and how this is modulated during genomic stress. Cells genetically deficient in G4-interacting proteins will enable detailed exploration of G4 formation and transcriptional effects. This highly interdisciplinary project will provide a wide range of excellent training opportunities exploiting the Balasubramanian group’s unique position with laboratories at the Cancer Research UK Cambridge Institute (CRUK CI) and the Department of Chemistry. Overall, the studies will generate novel functional insights in the G4 biology that may ultimately lead to the identification of mechanisms and pathways for new anti-cancer agents.";183454,8;183454,8;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;UK;;;;1;0;0;1;0;0 209019;750814;LITMUS;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Linked Irish Traditional Music Project;2017-07-01;2019-06-30;;"The LITMUS (Linked Irish Traditional Music) project will focus on the development of the first linked open data (LOD) framework tailored to the needs of Irish traditional song, instrumental music, and dance (ITM), as well as European and non-European traditional musics primarily propagated through oral transmission. LOD connects data from within & beyond knowledge domains; LOD ontologies are specially designed to represent knowledge structures and relationships. The few existing LOD music ontologies do not adequately express ITM & other oral traditions, making LITMUS significant. Project activities include ontology development, LOD infrastructure creation, & development of a publicly-accessible LOD pilot. LITMUS will impact the larger European cultural heritage community & beyond, providing a framework for other organisations to model & publish their own similar collections in LOD; reifying latent shared properties & traits anecdotally known to exist in the folk music of countries with strong socio-historical links. The researcher is uniquely positioned for implementing the LITMUS project through her combination of depth & breadth of knowledge in ITM, research in music information scholarship, & technological skills. Through LITMUS, the researcher will gain new technical skills, apply knowledge in multiple areas, gain insight into LOD industry research; synthesize current knowledge with new approaches using LOD, & gain high-level publication & presentation opportunities, thus greatly enhancing her employability in the non-academic sector. A variety of non-academic and academic audiences will be engaged in dissemination & communication of project results through presentations, demonstrations, videos, & workshops, including interdisciplinary music audiences. LITMUS will add value to ITMA's existing role as Project Partner & Content Provider for Europeana/Europeana Sounds whilst establishing ITMA as an international research focal point for LOD & traditional musics.";187866;187866;H2020-MSCA-IF-2016;/MSCA-IF-EF-SE;IRISH TRADITIONAL MUSIC ARCHIVE/TAISCE CHEOL DUCHAIS EIREANN LBG;IE;;;;1;0;0;1;0;0 208989;749788;PHOTORNA;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Development of photoswitchable ligands for the reversible and selective assembly with RNA;2017-10-01;2019-09-30;;"The proposed project aims at the development of novel functional ligands whose association with ribonucleic acid (RNA) is reversibly activated by light. As several RNA forms are essential key elements in physiological processes, the control of their function or malfunction by the reversible binding of photoswitchable ligands possesses a great potential as a tool in anticancer, antiviral and antimicrobial therapy. Surprisingly, this innovative approach towards a controlled reversible generation of RNA binders was mainly neglected in this highly topical research field. Hence, in this project photochromic hemi-indigo and fulgide derivatives are chosen as a platform for the design of photo-responsive RNA ligands, because i) they exhibit general features of RNA binders; ii) their structure can be reversibly modified by light, iii) the core structures are readily synthesized, and iii) the substitution pattern can be easily varied to enable fine-tuning of binding selectivity based on structure-activity relationships. In addition, conjugates that comprise two photoactive RNA-binding units will be obtained and studied because such bifunctional binders are expected to have very high affinity and selectivity toward RNA. An extensive library of derivatives will be synthesized and tested for their photocontrollable association with RNA. As a special method, real-time NMR-spectroscopic studies with direct irradiation of the sample inside a specifically designed spectrometer will be used to assess in detail the dynamics in the course of the photoinduced ligand–RNA interactions. Overall, it is anticipated that this systematic approach will enable the identification and development of lead structures for controllable RNA-targeting drugs with a great pharmacological potential. Moreover, the high interdisciplinary, innovative character of this challenging project gives the researcher an excellent opportunity to achieve professional maturity and open up best career possibilities.";159460,8;159460,8;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;UNIVERSITAET SIEGEN;DE;;;;1;0;0;1;0;0 210135;723241;TryptoBoost;SIGNED;H2020-EU.1.1.;ERC-2016-COG;H2020;Boosting tryptophan fluorescence with optical nanoantennas to watch label-free protein dynamics with single molecule resolution at high concentration;2017-10-01;2022-09-30;;Proteins execute a broad range of functions that are central to life. Understanding these functions ultimately requires experiments at the single protein level to reveal dynamics and heterogeneities hidden in ensemble-averaged measurements. Currently, the preferred method to study single protein machineries is based on fluorescence techniques. However, fluorescence experiments suffer from major challenges: the need for external fluorescent labeling, weak signals and low non-physiological concentrations in the nanomolar range. These challenges severely limit the applicability and biological relevance of single molecule fluorescence on proteins. The TryptoBoost project aims to overcome all the previous challenges, and efficiently monitor single label-free proteins using their intrinsic tryptophan fluorescence enhanced by optical nanoantennas in the ultraviolet. Using the natural amino acid fluorescence rules out all drawbacks due to external labeling, while the optical nanoantennas enable single protein analysis at the physiologically relevant micromolar concentrations thanks to the localization and enhancement of light-matter interactions at the nanoscale. To demonstrate the power of this new technology, our interdisciplinary team will probe the important biological problems of amyloid aggregation and tumor suppressor p53 protein folding dynamics at high concentrations. The TryptoBoost approach is directly applicable to any protein containing aromatic amino acids. This condition is met by more than 90% of human proteins, so the project breakthroughs will benefit a broad range of biophysical, chemical, and medical applications. For instance, it will improve the development of therapeutic drugs, increase the detection sensitivity and read-out speed in analytical biosensing on chip, and provide new nanostructures to enhance ultraviolet photocatalysis.;1947208,13;1947208;ERC-2016-COG;/ERC-COG;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FR;;;;1;0;0;1;0;0 209414;753812;ECtomics;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Dissecting spinal cord ependymal cell heterogeneity by single-cell transcriptomics;2017-04-01;2019-03-31;;Cells with stem cell potential, this is with the ability to self-renew and generate specialised progeny, exist in the adult mammalian spinal cord. Previous studies localised this potential within the ependymal cell (EC) population. However, ECs are rather heterogeneous based on their morphological features and the expression of a handful of neural stem cell markers. In this interdisciplinary research proposal, I aim to uncover the cellular and molecular heterogeneity of ECs at the level of individual cells. I propose to take advantage of cutting-edge single-cell RNA-sequencing technology to obtain the transcriptomes of individual ECs from the spinal cord of adult mice. Using advanced computational methods, I will establish EC types and states and use pseudotemporal ordering to elucidate potential lineage relationships among ECs. I will then validate these findings in the tissue context, using high-resolution confocal microscopy. This first comprehensive characterisation of spinal cord ECs will provide novel and fundamental insights into how ECs possess and maintain their unique self-renewing properties. In the future, this will facilitate realisation of the potential of spinal cord stem cells for therapeutic purposes.;183454,8;183454,8;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;UNIVERSITY OF DUNDEE;UK;;;;1;0;0;1;0;0 210327;751376;C-mapER;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Innovative learning platform for knowledge integration in Energy Retrofit;2017-09-18;2019-09-17;;"This proposal revolves around two specific questions: 1) to what extent multidisciplinary strategies to improve energy performance of existing buildings and neighbourhoods can be integrated; and 2) how this integration can bring technology and sustainable redevelopment of existing buildings together. It aims to develop an innovative learning platform for Knowledge Integration in Energy Retrofit (C-mapER) to develop the skills to manage complexity inherent in retrofit projects. An alternative method and an associated platform to evaluate and manage complexity, through a novel application of meaningful learning activities in designing technological solutions for energy retrofit, is the main vehicle.The objectives are to: 1) develop a conceptual framework of the key concepts and relationships that influence Energy Retrofit projects in workpackage 1 (WP1), 2) develop the beta version of the platform (WP2); and 3) test, refine, verify and disseminate the platform (WP3).The ultimate goal is to revolutionalise the traditional approach to educating future professionals, which is currently based on rote learning. This study will deliver an innovative learning platform and approach to develop practitioners who are well-placed to improve the energy performance of existing buildings through inter-disciplinary collaboration. The platform will address the lack of programs dedicated to interdisciplinary education, which helps develop the capacity to transfer information and knowledge between disciplinary boundaries and to deal with the tensions between social, economic, environmental and technological dimensions of sustainability. The outputs can be exploited at different levels within higher education sectors and professional development. By doing so, and in accordance with the main topic of the Marie Curie Individual Fellowship Action, new opportunities for developing the candidate’s career at the international level are created. It is anticipated that this Fellowship will create opportunities for inter-disciplinary teaching both within the host Faculty, across Oxford Brookes University, and beyond. It therefore has the potential to become a showcase exemplifying how research and teaching can be inter-linked.";183454,8;183454,8;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;OXFORD BROOKES UNIVERSITY;UK;;;;1;0;0;1;0;0 209145;724690;PICKLE;SIGNED;H2020-EU.1.1.;ERC-2016-COG;H2020;Planetary Interiors Constrained by Key Laboratory Experiments;2017-10-01;2022-09-30;;"The knowledge of interiors of rocky planets of our solar system (Mercury, Venus, Earth and Mars) is important for understanding their formation, present state, and evolution. The comprehension of differences and similarities in the internal constitution and processes will shed a new light on the origin and evolution of the solar system. Space missions are invaluable to this planetary quest. Yet, only geodesy data so far provided constraints on planetary deep interiors. Seismic observations on planetary bodies other than Earth are limited to the Apollo records for the Moon. The main objective of the forthcoming InSight mission is to place a seismometer on Mars to study its interior. However, the interpretation and full exploitation of geodesy and seismic data to produce accurate models of planetary structure and dynamics (internal convection and magnetic field generation) is critically hampered by the dearth of knowledge of key physical parameters of pertinent materials at relevant pressures (P) and temperatures (T). Thus this proposal aims at developing techniques and methodologies, combining innovative laboratory and synchrotron measurements, to acquire such physical properties at high pressure and temperature. I propose to measure sound velocities and acoustic attenuation of minerals and aggregates forming the mantle of telluric planets, as well as the phase diagram and melting curves of iron alloys forming their core. I will implement novel approaches to provide unprecedented determination of thermo-elastic properties of liquid iron alloys at P-T conditions directly relevant to the core of Mercury and Mars. Such information will be integrated together with geophysical data to infer new planetary models. This interdisciplinary project will contribute to understand the processes that shaped the rocky planets of the inner solar system, addressing fundamental questions related to their past and present dynamics.";1596500;1596500;ERC-2016-COG;/ERC-COG;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FR;;;;1;0;0;1;0;0 209737;725961;EU-FER;SIGNED;H2020-EU.1.1.;ERC-2016-COG;H2020;Economic Uncertainty and Fertility in Europe;2017-09-01;2022-08-31;;"EU-FER is a project about Economic Uncertainty and FERtility in EUrope. Economic uncertainty may be interpreted as an individual risk factor, mainly related to the labour market (e.g. unemployment, short-term contract jobs, underemployment, or a combination of these), but it may also be conceptualized as a macro-level phenomenon, reflecting the general uncertainty felt by people in times of economic turbulence. The recent Great Recession, spanning 2007 to 2009 and featuring downturns in both financial and labour market fortunes, has fuelled interest in understanding whether economic uncertainty, which does not appear to be a transient phenomenon, affects fertility. The economic uncertainty/fertility nexus is far from being clearly understood: theoretical premises are weak and empirical findings send conflicting messages. The goal of this project is to generate new knowledge on if, how, and under what circumstances economic uncertainty matters for fertility in contemporary Europe, adopting a cross-country comparative approach. The use of new data, methodologies, and tools may advance our knowledge on this topic. EU-FER is based on three pillars: a meta-analysis of previous research, a cross-country laboratory experimentation design, and micro-level longitudinal analyses. EU-FER ensures a strong interdisciplinary perspective, with the following overall goals: • to advance the understanding of the causal impact of economic uncertainty on fertility addressing this issue in a comprehensive way and from different perspectives, using various measures of uncertainty, and testing aspects that remain unclear from the current body of research; • to enhance the boundaries of demographic research by illustrating the benefits of a laboratory experimentation design; • to communicate findings and stimulate the academic and policy debate on how economic uncertainty matters for fertility.";1689272;1689272;ERC-2016-COG;/ERC-COG;UNIVERSITA DEGLI STUDI DI FIRENZE;IT;;;;1;0;0;1;0;0 209057;752520;SOLSTORE;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Solid-state reactions for thermal energy storage;2017-03-15;2019-03-14;;"In this project proposal reversible solid-state chemical reactions (eutectoids, peritectoids) are proposed for the storing of thermal energy at high temperature (300-800 °C). The development of a novel heat storage concept, based on solid-solid reactions, proposed in this project, could contribute to open new scenarios in the thermal energy storage field. To the best of our knowledge, the use of this class of reactions for TES applications has not been explored so far. The goal of this study is the identification of solid-state reactions fulfilling a large number of scientific and technological requirements (high storage capacity, good thermal conductivity, mechanical and chemical stability, complete reversibility of a charging/discharging cycles etc.). For this scope, an interdisciplinary research strategy will be followed involving materials chemistry, physics and engineering disciplines to achieve a complete overview of their behaviour starting from basic research challenges, focused on the material development and characterization (reactivity, stability, kinetic, reversibility, heat and mass transfer etc.), up to arrive to the investigation of their feasibility in real applications (e.g. concentrated solar power technologies (CSP) and waste heat recovery). During the project a two direction transfer of knowledge will be applied. On one side, an intense training will be offered to the applicant by the host laboratory with the objective to increase his scientific and managerial skills. Secondment in one established European technological center with recognized international expertise in concentrating solar plants (CSP) technologies is also planned. On the other side, the applicant will make available the knowledge and competences matured along his career both to give an impulse to the scientific work and fulfil the objectives set in the project and to explore other funding opportunities and collaborations.";161590,22;161590,22;H2020-MSCA-IF-2016;/MSCA-IF-EF-CAR;CENTRO DE INVESTIGACION COOPERATIVADE ENERGIAS ALTERNATIVAS FUNDACION;ES;UNIVERSITE DE BORDEAUX;FR;;1;0;0;1;0;0 209630;751236;REBUILD;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Mechanisms of sarcomeric protein homeostasis during physical exercise and ageing;2017-04-01;2019-03-31;;"During ageing muscle fibers are constantly subjected to high forces resulting in mechanical stress on cells and proteins. As a consequence they can degenerate, leading to suboptimal force generation, lack of coordinated movements and ultimately to muscle failure in the elderly population. This ageing process that leads to a progressive loss of muscle function has a major health impact on the ageing Western society. Physical activity is known to delay this decline. The REBUILD project aims to determine the temporal dynamics of protein replacement during life of a muscle fiber by SILAC-based mass spectrometry and genetics. It will integrate biomechanics with muscle homeostasis and accurately quantify the impact of physical activity on protein turnover and investigate the physiological consequences for the ageing animal. By combining the power of genetics and SILAC-based proteomics with behaviour of free flight under defined exercise conditions, we create a unique position for a discovery orientated large-scale in vivo genetic screen. The interdisciplinary nature of the project will allow establishing novel hypothesis, combining muscle biomechanics as a driving force behind dynamic maintenance of the muscle tissue during ageing. The experienced researcher will expand on previous training acquired in San Francisco, USA, and establish a new line of research in the crossroads of two developing fields (quantitative proteomics and biomechanical regulation of tissue homeostasis). This will be a stepping stone for his scientific independence. The host will expand on its expertise on developmental regulation of muscle formation and benefit from the expertise of the candidate in the biology of ageing and homeostasis. A precise understanding of mechanisms that control homeostatic replacement of damaged proteins in muscle fibers should foster interventions aimed at maintenance of muscle capacity in older individuals and thus, an important step towards healthy ageing.";185076;141203,25;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FR;;;;1;0;0;1;0;0 210308;747045;MIMICS;CLOSED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Electromyography-driven musculoskeletal modelling for biomimetic myoelectric control of prostheses with variable stiffness actuators;2018-09-01;2020-08-31;;"Upper limb loss affects 94.000 individuals in Europe. Advanced treatments rely on myoelectric prostheses controlled by amputees’ electromyograms or EMG. Despite expected benefits, today's schemes provide limited re-gain of functionality and lack of bio-mimesis, i.e. they use: (1) direct mapping between EMG and prosthesis joint angle, disregarding underlying neuromusculoskeletal processes, and failing to generalize to unseen conditions (robustness lack), (2) stiff actuators not mimicking biological compliant joints, preventing natural motion (functionality lack). MIMICS proposes a biomimetic paradigm: (1) a modelling formulation that simulates amputee’s phantom limb musculoskeletal dynamics as controlled by EMGs, and (2) prostheses with variable stiffness “soft” actuators. This opens to next-generation “soft” prostheses that can mimic biological limb functionality and robustness; a priority of current European policies and technology roadmaps, with estimated initial markets for functional myoelectric prostheses of €1 billion. MIMICS combines required interdisciplinary skills on soft actuation (host), neuromusculoskeletal modelling (fellow), and clinical bionic reconstruction (secondment). The career development plan is tailored on fellow’s needs: new skills acquisition (soft actuation/clinical prosthetics), project/teamwork management, open science/gender aspects care, ERC grant writing support. The action transfers fellow’s pre-acquired knowledge to the host and opens cooperation with secondment institute, thus increasing host’s visibility in myoelectric control and clinical prosthetics. The secondment expands MIMICS outcomes to boarder clinical perspectives and boosts knowledge transfer among organizations. Outreach activities plan to improve public understanding of MIMICS achievements, socio-economical potentials and clinical benefits. This all is set to improve fellow’s career prospects and form a European network of excellence in neurorehabilitation technologies";168277,2;168277,2;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA;IT;;;;1;0;0;1;0;0 200997;701958;OXFLUX;TERMINATED;H2020-EU.1.3.2.;MSCA-IF-2015-GF;H2020;Oxidised organic vapours in the atmosphere: From fluxes to chemical mechanisms and impacts;2016-03-01;2019-02-28;;"The oxidation of volatile organic compounds (VOC) in the atmosphere has crucial effects on aerosol particle formation, hence on the budget of cloud condensation nuclei, and thus on climate. The oxidation of certain biogenic VOC can quickly lead to highly oxygenated organics with very low volatility that have recently been found to play critical roles in all stages of aerosol formation. However, only a fraction of the underlying oxidation mechanisms is currently known, and open questions remain about how the full distribution of oxidation products interacts with the aerosol phase. Moreover, the problem of VOC oxidation is highly interdisciplinary, as it is subject not only to chemical reactions, but also to precursor emissions, natural climate feedbacks and anthropogenic perturbations, depositional losses, and mixing. The aim of OXFLUX is to reveal the formation mechanisms and subsequent fates of important VOC oxidation products, to better quantify their impacts on atmospheric chemistry, in particular on aerosol formation and growth, and ultimately on cloud formation and climate. The Experienced Researcher (ER) will address this challenge experimentally by combining novel mass spectrometric techniques, able to directly measure hundreds of VOC oxidation products, with flux measurements. Fluxes will be measured from towers in temperate and boreal forests, as well as from aircraft. These ambient measurements and their interpretation will be supported by laboratory studies and chemical transport modelling. During the return phase in Europe, the ER will establish continuous flux measurements of oxidised organics in a boreal forest in Finland, and collaborate with atmospheric modellers to include his findings in boundary layer simulations. The ambitious project’s host organisations are world leaders in the field of research and the involved experimental and analytical techniques, maximising the chances of the project’s success and its beneficial impact on the ER’s career.";267793,2;267793,2;H2020-MSCA-IF-2015;/MSCA-IF-GF;HELSINGIN YLIOPISTO;FI;;;;1;0;0;1;0;0 201068;702705;AGENTSEGET;TERMINATED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Itinerant Cultural Agents in Early Modern Europe and the Scotsman Thomas Seget: A Case-Study;2016-09-01;2018-08-31;;AGENTSEGET is an interdisciplinary project that will explore a neglected type of intellectual who grew to prominence in Europe at the end of the sixteenth century, a time of significant social and cultural upheaval. The religious conflicts, political tensions, and profound intellectual transformations of the decades around 1600 called for new styles of communication often involving subterfuge, middle-men, and disguise. A different type of intellectual was required to connect scholars in different and often troubled areas of Europe. Their task was to deliver scientific instruments, precious books and manuscripts crucial to the production of new knowledge and theories. To support themselves, they also traded information about princes, governments, religious factions and political machinations. The project will focus on the Scotsman Thomas Seget (1569/70-1627), one of the most interesting and less studied examples of this type of intellectual. By using Seget as a case study, AGENTSEGET aims to unlock the rich and vibrant personal and professional network of intellectual brokers and cultural middlemen in which prominent scientists such as Kepler and Galileo operated and thrived, exchanging ideas and receiving informal feedback on their work. The findings of AGENTSEGET are expected to demonstrate that cultural and scientific mobility has always been an essential component of the circulation and development of cutting-edge scientific research. The results will be disseminated through a monograph, Open Access publications, an interactive website, an edited volume, an exhibition, and a series of educational activities.;183454,8;183454,8;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;THE UNIVERSITY OF EDINBURGH;UK;;;;1;0;0;1;0;0 200999;701981;THAUMECOPHYL;TERMINATED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Evolutionary history and ecological adaptations of ammonia oxidizing Thaumarchaeota.;2016-04-01;2018-03-31;;Ammonia oxidizing archaea (AOA), a clade of the Thaumarchaeota phylum, diversified in a variety of marine and terrestrial environments. Due to their abundance, AOA are deemed major players in the global cycle of nitrogen. They also produce greenhouse gasses. Despite their ecological importance, the nature and origin of ammonia oxidizing metabolism and the reasons for the ecological success of AOA are still unknown. This project aims at performing the first comprehensive evolutionary and comparative genomic analysis of Thaumarchaeota to identify crucial metabolic and genomic features. Prof. Schleper is a leading scientist in Thaumarchaeota cultivation, genomics and physiology. Metagenomic data produced in her laboratory give now access to genomes of crucial taxa for this project. I will complete these genomes, and analyse all available AOA genomes with a sophisticated model of genome evolution to reconstruct the species tree of Thaumarchaeota and the events (gene duplications, transfers and losses) that occurred along their evolution. The genome of the AOA’s ancestor will be inferred, and the minimal gene set required for ammonia oxidation identified. The sets of evolutionary events and the ancestral genome will be linked to metabolic and ecological transitions to obtain the scenario of ammonia oxidation emergence and of the adaptation of AOA to various environments, thus addressing key questions in the fields of ecology, evolution, and archaea biology. This interdisciplinary project is only possible through the unique combination of my expertise in comparative genomics and molecular phylogeny with the expertise of Prof. Schleper's group, which will result in two-ways transfers of knowledge and skills. Beyond scientific training, I will be trained to project management and project design with experimental biologists. This is crucial for my career, as I plan to start a group at the edge of bioinformatics and experimental biology to study how complex systems evolve.;178156,8;178156,8;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;UNIVERSITAT WIEN;AT;;;;1;0;0;1;0;0 200433;701709;CARMI;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Cosmology, Astronomy, and Religion in Medieval India;2017-06-01;2019-05-31;;"CARMI proposes to study the friction between two cosmologies found in India in medieval times: the cosmological model used by the astronomical tradition of India, and the cosmology found in the Pur??as, a group of texts sacred in Hinduism. In the Indian tradition, cosmology falls within the branch of knowledge known as jyoti?œ?stra, which has three divisions: sa?hit? (omens); hor? (astrology); and ga?ita (the astral sciences, including astronomy and cosmology). With CARMI present, the Department of Cross-Cultural and Regional Studies will have experts in all three divisions, creating a unique research environment for the study of all aspects of jyoti?œ?stra. This will be particularly valuable for CARMI. Historically, the Indian astronomers rejected elements from the Pur??as contradicting their model, but also incorporated compatible elements. With the astronomer J??nar?ja (1500 CE), this changed; he sought to create a synthesis between the two incompatible cosmologies. He maintained that the sacred Pur??as could not be contradicted. At the same time, he needed a working science. So he re-interpreted passages from the Pur??as. This approach had a significant impact on Indian astronomy. What were the dynamics that led to this approach? Why was it felt necessary to assert the authority of the Pur??as within the Indian astronomical tradition? Through a careful investigation of J??nar?ja's sources, CARMI will have an interdisciplinary approach to the understanding of issues arising from the interaction of cosmology, on the one hand, and religion, on the other (that is, two separate subfields of Indology), in medieval India (ca. 1200 to 1500 CE) based on the analysis of primary Sanskrit sources.";212194,8;212194,8;H2020-MSCA-IF-2015;/MSCA-IF-EF-RI;KOBENHAVNS UNIVERSITET;DK;;;;1;0;0;1;0;0 200445;703542;ArCH4ives;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Unlocking the methane cycling archives from Arctic lakes: a biological fingerprint;2016-03-01;2018-12-02;;Arctic landmasses and lakes release significant amounts of methane (CH4), a potent greenhouse gas that contributes to global climate change. Yet, the effect of rapid warming in the Arctic on the fate of CH4 emissions is poorly understood, particularly over decadal to millennial timescales. The recent advance of high-throughput sequencing and metabarcoding techniques to analyse ancient environmental DNA, or paleogenomics, from Arctic lake sediment has tremendously heightened analytical sensitivity and thus unlocked a wealth of new information on past ecosystems and their processes. I will combine this innovative approach to a robust paleoecological framework and multivariate analyses to study the drivers underpinning microbial assemblages involved in the cycling of CH4 during major periods of climate variability in Greenland since deglaciation. By using an important multi-site set of lake sediment cores spreading along major environmental gradients and collected by the Anthropocene-Quaternary Research Group, I will upscale the study from catchment to region and from the present Anthropocene (~last 150 years) to the early deglaciation of the Holocene (~11,700 years ago). This dataset will also enable me to control for the different catchment-specific processes that may have influenced microbial abundance, diversity and function in the past, and isolate the influence of climate on their ecology. This interdisciplinary approach will be supported by the analysis of additional paleoecological proxies for other important components of the carbon cycle in Arctic watersheds via collaborations with Canadian and Australian laboratories. While acquiring new expertise in cutting-edge paleogenomics and microbial ecology in world-leading research facilities at the Centre for GeoGenetics, I will advance paleoecology, gain significant new insights into the global carbon cycle and improve our understanding of the sensitivity of polar ecosystems.;212194,8;212194,8;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;KOBENHAVNS UNIVERSITET;DK;;;;1;0;0;1;0;0 206464;706636;IMAGENE;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-GF;H2020;Characterizing Function Genetic Variants Linking Immunity and Psychiatric Disorders;2017-08-01;2020-07-31;;"Understanding genetic risk for disease is one of the major goals in human genetics. Genome-wide association studies (GWAS) have identified thousands of genetic variants associated with complex human diseases, the majority of them locating in regulatory regions outside of genes. The identification of functional regulatory variants underlying such GWAS associations and understanding their pattern of activity is the key for understanding biological processes behind each genetic association to disease – and without such understanding, targeted interventions and drugs to affect the relevant pathways are not possible. IMAGENE will elucidate the role of functional genetic variants that link immunity and psychiatric disorders such as schizophrenia. This will be achieved by combining state-of-the-art technologies in genome engineering, Next-Generation sequencing and computational biology, which will allow obtaining mechanistic insight into genetic risk of human diseases at unprecedented depth. The applicant has unique interdisciplinary skills to carry out the project, including clinical background and basic research experience in the different fields united in this proposal – human genetics, immunology, and psychiatry. The impact of the project could be enormous, since elucidating the molecular mechanisms of disease-associated variants that link immune function to disease pathology of schizophrenia could contribute to the development of novel treatments for this disease.";257860,8;257860,8;H2020-MSCA-IF-2015;/MSCA-IF-GF;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;DE;;;;1;0;0;1;0;0 210597;754326;POLITICO;SIGNED;H2020-EU.1.3.4.;MSCA-COFUND-2016;H2020;Political Concepts in the World;2018-01-01;2022-12-31;;"The POLITICO PhD programme will build on the success of the interdisciplinary training provided by the University of Aberdeen’s Centre for Citizenship, Civil Society and the Rule of Law (CISRUL), which specializes in the global application of political ideas. 2 cohorts of 6 high-quality international ESRs will propose and develop their own research projects around the theme of how political concepts are deployed in the world. POLITICO ESRs will ask how, and with what consequences, policy institutes, social movements and media commentators invoke such ideas such as ‘nation’, ‘democracy’ and ‘civil society’. POLITICO will reach beyond the West to locate political ideas in South, Central and Eastern Europe, the Middle East and North Africa, South and East Asia, and Latin America and the Caribbean. Selection will be via an open, transparent, merit-based, impartial, equitable and internationally advertised process, which will take special care to allow free choice of research projects. With POLITICO’s inter-disciplinary supervision and inter-sectoral training, the ESRs will build careers not only in state-of-the-art research, but also in incisive policy design, social movement leadership, and influential media commentary. In these careers, the researchers will apply their acute awareness of how political concepts vary across contexts and are invoked in political action. To further develop the ESRs’ inter-disciplinary expertise, and to provide opportunities to present research and engage in debate, CISRUL will host a full series of seminars, workshops and conferences, all co-designed with ESRs and on topics that cross-cut POLITICO themes. POLITICO ESRs will be supported by 23 internationally-recognised partner organisations, committed to providing specific training to researchers across the POLITICO project themes. 6 of the partners are leading policy institutes that will provide inter-sectoral training to include the writing of policy briefs, expected of all ESRs.";1883520;941760;H2020-MSCA-COFUND-2016;/MSCA-COFUND-DP;THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN;UK;;;;1;0;0;1;0;0 210604;754462;EuroTechPostdoc;SIGNED;H2020-EU.1.3.4.;MSCA-COFUND-2016;H2020;International Network of Excellence in Science Technology;2017-06-01;2022-05-31;;Combining complementary research & innovation strengths with unique infrastructures across four leading European Universities of Science & Technology will provide the basis for an internationally competitive fellowship programme. The new EuroTechPostdoc programme aims at attracting excellent experienced researchers from all over the world through an open, transparent and structured recruitment process. EuroTechPostdoc will provide exceptional research and training opportunities for up to 80 experienced researchers funded for a 2-year period (divided in 2 calls, 10 fellowships per participant per call). The fellows will develop their skills in interdisciplinary collaboration projects between at least two participants from two different European countries, and will be provided with the opportunity to transfer knowledge in entrepreneurship activities or by collaboration with public and industrial organisations from the combined networks of the participants. The research programme has been carefully selected to provide the fellows with the complementary strengths, established networks and industrial collaboration in areas of high relevance to the EU’s industrial leadership: Health & Bioengineering, Smart & Urban Mobility, Data Science & Engineering, High Performance Computing, Entrepreneurship & Innovation. The fellows will gain access to the excellent and complementary training options offered at the four participants, and will be supported by a personal supervision and mentoring scheme, as well as excellent local support structures. The EuroTechPostdoc 3-days Workshop focuses on strengthening the fellows’ skills and network, preparation ahead of their careers and to foster further collaborative projects between the fellows. Together with outstanding working conditions that support both family and career, the programme will thus provide the fellows with unprecedented possibilities to diversify their career options for a leadership position within the ERA.;11328000;5664000;H2020-MSCA-COFUND-2016;/MSCA-COFUND-FP;TECHNISCHE UNIVERSITAET MUENCHEN;DE;;;;1;0;0;1;0;0 209690;754422;INTREPiD;SIGNED;H2020-EU.1.3.4.;MSCA-COFUND-2016;H2020;CRG International Research Postdoctoral Programme;2017-09-01;2022-08-31;;INTREPiD is an innovative 5-year Fellowship Programme that aims at recruiting 12 experienced researchers at the Centre for Genomic Regulation (CRG) located in the Barcelona Biomedical Research Park (PRBB), one of the largest biomedical research clusters in southern Europe. Fellows will be selected following an open, transparent, and merit-based process, based on international peer-review, and offered attractive working conditions in line with the European Charter and Code (the CRG was awarded the HR Excellence in 2013). Selected researchers will be able to develop their own project under the supervision of the group leader they select. They will be offered international, interdisciplinary and inter-sectorial mobility opportunities in a highly creative and dynamic environment supported by cutting-edge core facilities and a vibrant network of collaborators from academia and the private sector. INTREPiD will provide tailored mentoring and a comprehensive training programme, including up-to-date scientific and technological courses in a wide range of topics and disciplines, and modules on transferable skills, entrepreneurship, open science and career development. Mobility to national and international academic and non-academic institutes will be encouraged, in one of the partner organisations or in institutes that research labs collaborate with. Overall, the INTREPiD Programme will provide fellows unique skills and competences for developing a successful career in both the academic and non-academic sector. Thanks to the large CRG network of collaborators locally and internationally, the Programme will also catalyse sharing of best practice in experienced researchers training programmes across different institutes.;2548800;1274400;H2020-MSCA-COFUND-2016;/MSCA-COFUND-FP;FUNDACIO CENTRE DE REGULACIO GENOMICA;ES;;;;1;0;0;1;0;0 209327;750459;BrainPredictDynamics;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Temporal predictions in the auditory cortex: neural mechanisms and their specificity across species and stimulus domains;2018-09-01;2021-08-31;;"Following a recent paradigm shift in neuroscience, the brain is often thought to generate active predictions of its environment. Neural predictions of temporal information, in particular, are a current research frontier. A key challenge is to provide a unifying mechanistic explanation of neural expectations ranging from microscopic electrophysiology, via models of interacting populations of neurons, to macroscopic signals observed non-invasively. Auditory and speech perception are the optimal testing ground for studying temporal dynamics of predictive processing in the brain, as most auditory signals only gain meaning as temporal sequences. This project aims at (1) providing a mechanistic model explaining how temporal expectations influence neural activity in auditory cortex across species (rats and humans), and (2) test whether the mechanisms established for simple auditory stimuli generalise to rich, complex and hierarchical structures characteristic of speech stimuli. These research objectives will be addressed in a coherent programme based on well-controlled psychoacoustic and psycholinguistic experiments, combining extracellular electrophysiology in rats and neuroimaging (magneto- and encephalography) in humans with novel analytic tools. By integrating knowledge from disparate fields such as systems-level neuroscience and psycholinguistics, the project will yield novel and unique evidence testing the generality (across species and stimulus domains) and specificity (regarding the proposed neural mechanisms) of the influential theories construing the brain as an inherently predictive organ. Besides its immediate research objectives, the current project is optimised to provide me with training necessary to reach professional independence, complementing my interdisciplinary expertise in an innovative research field across different species and cognitive domains, and consolidating my project coordination, management and leadership abilities.";251611,2;251611,2;H2020-MSCA-IF-2016;/MSCA-IF-GF;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;DE;;;;1;0;0;1;0;0 209999;754433;STARS;SIGNED;H2020-EU.1.3.4.;MSCA-COFUND-2016;H2020;SupercompuTing And Related applicationS Fellows Program;2018-01-01;2022-12-31;;The BSC STARS (SupercompuTing And Related applicationS) International Research Fellows program aims at fostering the training of highly skilled post-doc in all fields of High Performance Computing and related applications, specifically in Earth Science and Meteorology, in Life Sciences, Genomics and Personalised Medicine and in Computational Engineering and Physics and Computational Societies, providing them with all the necessary tools for developing their potentials, deepening their skills and knowledge in a stimulating, international and interdisciplinary environment, offering them intersectorial secondments with private industry or non-academic Research centers, in order to boost their career perspectives as successful independent researchers.;2832000;1416000;H2020-MSCA-COFUND-2016;/MSCA-COFUND-FP;BARCELONA SUPERCOMPUTING CENTER - CENTRO NACIONAL DE SUPERCOMPUTACION;ES;;;;1;0;0;1;0;0 209852;754465;FRESCOatCNAP;SIGNED;H2020-EU.1.3.4.;MSCA-COFUND-2016;H2020;FrontierResearchCompentences@CNAP;2017-04-01;2022-03-31;;"Chronic pain is a key societal challenge affecting one out of five adults and is in general poorly treated. This programme, FrontierResearchCompentences@CNAP (FRESCO@CNAP), aims to install 8 early stage researchers (ESRs) in a Centre-of-Excellence (CNAP) conducting frontline research on novel tools for identifying and modulating human pain mechanisms. CNAP is internationally recognised due to the multidisciplinary approach to the studies of pain. A main objective is to have the best possible research training. It is a clear vision to promote incoming mobility and bringing the best international talents to CNAP. Within the four CNAP interdisciplinary research groups, the ESRs will be trained within biomedical and neural engineering applied in basic and integrative neuroscience. The ESRs will be offered relevant collaborative research training and/or research visits to external research centres, i.a. FRESCO@CNAP partners including clinical and academic institutions (eight countries). Moreover, ESRs will obtain intersectoral exposure via the non-academic partners (six countries) connected to FRESCO@CNAP. The ESRs will receive individual training through research by undertaking PhD projects and PhD courses. PhD courses on transferable skills will be provided. Further, a dedicated workshop will be provided including the FRESCO@CNAP non-academic and academic partners. As a fundamental principle, FRESCO@CNAP will guarantee a fair, efficient, transparent, supportive, and internationally comparable recruitment process. CNAP will make use of international channels for advertising the PhD programme. International independent reviewers with no conflict of interest will conduct competence evaluations and a selection committee will make the final selection of the ESRs. Substantial impact is expected since FRESCO@CNAP will attract, qualify and retain researchers by offering an international, multidisciplinary, intersectoral and scientifically excellent research environment.";1255680;627840;H2020-MSCA-COFUND-2016;/MSCA-COFUND-DP;AALBORG UNIVERSITY;DK;;;;1;0;0;1;0;0 210003;754511;T4C;SIGNED;H2020-EU.1.3.4.;MSCA-COFUND-2016;H2020;PhD Technology Driven Sciences: Technologies for Cultural Heritage;2018-01-01;2022-12-31;;T4C is a novel research and training doctoral programme in “Heritage Sciences” conceived by the University of Torino, (UNITO) with the financial support of the banking foundation Compagnia di San Paolo (CSP) and the scientific and training involvement of a 35 local, national and international partner organisations belonging to academic and non-academic sectors. Main aim of T4C is to build up the next generation of Cultural Heritage professionals, able to develop technological solutions and services for the restoration, the protection, the diagnostics and the valorization of cultural heritage and skilled with a complementary scientific training from socio-economic disciplines and humanities and soft skills. Target are early stage researchers with a scientific background in chemistry, physics, biotechnology, ICT, biology and related disciplines, undergoing a genuine mobility to Italy. T4C will last 60 months and will be implemented through 2 calls for applications, assigning a total of 18 transnational incoming fellowships. Fellows will be offered an independent and personalized scientific training choosing from two specific scientific domains: Digital Sciences and Conservation, within the specific panels of Digital Sciences, Physical Sciences, Basic and Natural Sciences, Environmental Sciences They will be enrolled in the T4C PhD programme and will be supervised by a joint supervision of academic and non-academic supervisors. Fellows will attend an exclusive traninig programme, encompassing basic traninig, scientific training through individual project implementation and interdisciplinary training, short term visits, secondment opportunities at non-academic premises, soft skills, dissemination and outreach activities. T4C intends also to capitalize on the experience of the already funded Cofund project (Train2Move) in managing international mobility programmes with national and international impact and in aligning national mechanisms to EU ones.;2825280;1412640;H2020-MSCA-COFUND-2016;/MSCA-COFUND-DP;UNIVERSITA DEGLI STUDI DI TORINO;IT;;;;1;0;0;1;0;0 198320;676144;SyDAD;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2015-ETN;H2020;Synaptic Dysfunction in Alzheimer Disease;2015-11-01;2019-10-31;;"Given an overwhelming increase of dementia costs and an aging population, there is an urgent need for finding novel therapies for Alzheimer Disease (AD). We are, however, facing a large number of failed clinical trials and a retraction of the nervous system R&D programmes from several big pharmaceutical companies. Increased collaboration between academia and the private sector is required to overcome this challenge. The “Synaptic Dysfunction in Alzheimer Disease” (SyDAD) project will significantly contribute to this approach by training a new generation of researchers with experience and full understanding of the requirements of academia, pharmaceutical companies, the clinics and the society. The research programme will focus on synaptic dysfunction, the main connection point between pathology and cognitive decline in AD. Given the complementary expertise, SyDAD will have excellent opportunities to delineate the cross-talk between different pathways underlying synaptic dysfunction in AD and to identify novel pharmaceutical targets. For future implementation of the research findings into clinical trials, a drug discovery platform will be elaborated, utilising the industrial and clinical expertise in the network. The early-stage researchers (ESRs) will be trained in this environment and provided with a mind-set of future commercial and clinical utilisation of their research findings. Apart from the innovative and collaborative approach of the research programme, the ESRs will also be provided with a training programme where cutting-edge methodology, innovation and transferable skills are key components. The trained ESRs will have excellent intersectoral and interdisciplinary career opportunities and will, together with the SyDAD partners, provide a solid ground to tackle one of the major societal challenges of our century: Finding therapies to decrease the suffering and economic burden of AD patients.";3846736,44;3846736,44;H2020-MSCA-ITN-2015;/MSCA-ITN-ETN;KAROLINSKA INSTITUTET;SE;"AXON NEUROSCIENCE SE;DEUTSCHES ZENTRUM FUR NEURODEGENERATIVE ERKRANKUNGEN EV;UNIVERSITE DE BORDEAUX;UNIVERSITA DEGLI STUDI DI MILANO;JANSSEN PHARMACEUTICA NV";"SK;DE;FR;IT;BE";;1;0;0;1;0;0 216434;778010;IPaDEGAN;SIGNED;H2020-EU.1.3.3.;MSCA-RISE-2017;H2020;Integrable Partial Differential Equations: Geometry, Asymptotics, and Numerics.;2018-01-01;2021-12-31;;"Partial Differential Equations (PDE's) undoubtedly are among the main tools for an efficient modelling of physical phenomena. Infinite-dimensional analogues of regular (integrable) behaviour, previously confined to the theory of systems with a finite number of degrees of freedom began to be considered in the middle of the XX century in fluid dynamics, field theory and plasma physics. The idea that an integrable behaviour persists in non-integrable systems, together with the combination of the state-of-the-art numerical methods with front-line geometrical and analytical techniques in the theory of Hamiltonian PDE's is the leitmotiv of this research project. Asymptotic regimes leading to phase transitions both in the theory of dispersive PDEs and the theory of Random Matrices display universality properties which can be analysed both numerically and analytically. The predictive power of numerics and scientific computing can be used both as a testing tool for theoretical models and as a generator of new conjectures. By focussing the expertise of front line researchers in different areas of Mathematics towards the study of critical phenomena in dispersive PDE's, we expect results in realms including differential and algebraic geometry, the theory of random matrices, multiscale analysis of PDE's as well as non-linear models of stratified fluid flows. The broad interdisciplinary basis and intertwining of methods of Geometry and Mathematical Physics will be instrumental in making the results accessible for the wider community. Younger (Ph.D. and/or Post-Docs) Researchers to be included in such an active and fertile research and training ground, will certainly seize their chance to enhance and broaden their skills.";886500;540000;H2020-MSCA-RISE-2017;/MSCA-RISE;UNIVERSITA' DEGLI STUDI DI MILANO-BICOCCA;IT;"UNIVERSITE D'ANGERS;SCUOLA INTERNAZIONALE SUPERIORE DI STUDI AVANZATI DI TRIESTE;COMMUNAUTE D' UNIVERSITES ET ETABLISSEMENTS UNIVERSITE BOURGOGNE - FRANCHE - COMTE";"FR;IT";;1;0;0;1;0;0 215260;794476;PEAI;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Public Epigraphy in Ancient Italy (third-first centuries BCE);2018-05-01;2020-04-30;;"The purpose of this project is therefore to compile palaeo-Italic public inscriptions to analyze their use as a means of social communication from the third to the first centuries B.C. Public epigraphy comprises the inscriptions intended for public display regardless of whether they were the result of an official or private initiative. These texts constitute a peculiar form of social communication which was quite typical in the ancient world. They were used for self representation and to spread and perpetuate a series of solemn messages linked to the fundamental values of society, in particular, the values of its élite. The chosen period, prior to the shaping of the so-called imperial epigraphic culture –which began under Augustus and involved an exponential increase in the ‘epigraphic habit’– is characterized by an incipient proclivity to produce public types of texts and, above all, by a diversity of epigraphic cultures, both with regard to language and script. The work plan consists of producing a census of public inscriptions and cataloguing them in an online database, including the direct analysis of a significant part of the inscriptions. These documents also allow us to study three specific aspects: linguistic changes and the ensuing possible implications on identity; the social groups which promoted them; and the privileged spheres of epigraphic and public communication. The result of my research will be disseminated through publication of papers, a seminar, a conference (PEI) and a monograph. Communication includes a booklet, QR codes, an Instagram account and a didactic activity. As regards my training, this project is fundamental as collaboration with my Supervisor will result in gaining linguistic knowledge to complete my interdisciplinary training, and the secondment will allow me to gain significant experience in Digital Humanities. The MSC allowing me to become a more mature and accomplished researcher capable of directing a research project.";168277,2;168277,2;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;UNIVERSITA DEGLI STUDI DI ROMA TORVERGATA;IT;;;;1;0;0;1;0;0 215367;795611;MATISSE;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;"Post-crisis urban transformations in Madrid and Athens; a comparative approach";2018-10-01;2020-09-30;;"Nearly a decade after its outbreak, the shockwaves of the 2008 global crisis remain omnipresent in Southern Europe. Rapid political, economic and institutional transformations have triggered the reshuffling of housing. Within this framework, transnational investors are entering local property markets, purchasing repossessed houses and/ or non-performing loans. Spain and Greece, and their capital cities Madrid and Athens, are two outstanding but contrasting examples of this socio-political and spatial restructuring. They provide crucial theoretical, methodological and analytical challenges for urban studies and a key opportunity for the development of a novel comparative-relational approach to learn about the local consequences of the strategies of these global actors. The project MATISSE will address three lines of inquiry, looking into: (i) which are the policies encouraging housing financialisation (ii) who are the transnational investors and; (iii) which are the social and spatial implications of such property restructuring. It will bring together an interdisciplinary approach based on a two-way knowledge transfer between the ER’s (Dr Georgia Alexandri) existing research in urban restructuring in Athens and Madrid with the Supervisor’s (Dr Stuart Hodkinson) extensive experience and research expertise in housing financialisation, privatisation and corporate mapping.";195454,8;195454,8;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;UNIVERSITY OF LEEDS;UK;;;;1;0;0;1;0;0 215298;794842;QQT;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Identification of quantum resources in thermodynamic systems;2018-04-03;2020-04-02;;"In this proposal we look at thermodynamics in extreme regimes, i.e. out of equilibrium quantum systems displaying coherence and entanglement, far from the thermodynamic limit and in single-shot scenarios. The main objectives are: 1) Creation of a thermodynamic dictionary that reconciles the resource-theoretical formalism with the variety of approaches to the field, clarifying the scope of abstract results in experimentally relevant scenarios, including restricted control and finite-time constraints. 2) Inclusion of quantum coherence and correlations in extreme quantum regime, beyond simple energy quantisation. We propose a new paradigm looking at the interplay of coherence and entanglement in thermodynamics and explore its consequences for cooling protocols and non-locality. 3) Presenting clear evidence of genuine non-classicality in thermodynamics. With the ultimate goal of providing a framework to achieve non-classical advantages, we propose to establish a new research venue looking at signatures of quantum contextuality in thermodynamics. We propose to devise experimentally testable protocols whose statistics defies any non-contextual explanation. This highly innovative proposal will be carried out with a host of world experts coordinated and led by the fellow. The great interdisciplinary content will significantly extend the applicant's expertise in the diverse areas of quantum thermodynamics, but also in contextuality, non-locality and their applications to computing and cryptography. Within a world-class institute like ICFO, the networking opportunities, involvement in the PhD programme and the training offered will allow the fellow to acquire the flexibility, critical thinking, broad horizon and supervision skills required to eventually lead a research group, either in academia or hi-tech industry.";158121,6;158121,6;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;FUNDACIO INSTITUT DE CIENCIES FOTONIQUES;ES;;;;1;0;0;1;0;0 215646;798502;PEREDEP;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Promoting E-Rulemaking in the EU through Deliberative Procedures;2018-08-02;2020-08-01;;"This project assesses the potential and limitations of ‘e-rulemaking’ in the European Union (EU). The theoretical approach employed in this research project addresses citizen participation and e-rulemaking through the lens of deliberative democracy theory and new media theory with specific references to legal theory. Along with the novel theoretical dimension that this project will propose regarding law-making procedures in the EU, the researcher aims to produce outcomes that are informed by relevant empirical analysis and are of practical value. To this end, she proposes to examine the specific erulemaking initiative at EU level, through the organization of a workshop with participants from all over Europe that will participate in a real e-rulemaking event in order to assess the potential and possible shortcomings of an e-rulemaking initiative in the EU. As the project aspires to provide valuable contribution to the current ‘Better Regulation” of the EC the researcher will reach her final conclusions after formal engagement and consultation with the Secretariat General of the EU and the newly established Regulatory Scrutiny Board (2016) which exercises a ‘quality assurance role” in the ‘Better regulation Agenda’ of the EC. The researcher aims to organize two short study visits at the European Commission for consultation with EU institutions and sharing of research results. The project addresses two major topics: responsible citizenship and the prerequisites for qualitative civic participation in an e-rulemaking initiative following-deliberative procedures.The project is in nature interdisciplinary as the research it proposes stands at the crossroads of political science (with specific attention to deliberation theory and participatory democracy), media studies (with specific attention to new media theory and e-participation) and certainly law as it refers to law making procedures in the EU.";187866;187866;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;DUBLIN CITY UNIVERSITY;IE;;;;1;0;0;1;0;0 211891;765395;PERFORM;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2017;H2020;Pioneering the Digital Future for Omnichannel Retail Managers;2018-01-01;2021-12-31;;"The overall goal of PERFORM is to establish a European training network to prepare the next generation of Digital Retail Managers. Established Business Models need to be revised as customer behaviour is changing. Customers no longer prefer online or instore purchasing but switch between channels to suit their own personal requirements. Innovative digital technologies such as Internet of Things, Big Data, advanced analytics as well as augmented reality novel payment systems and visualisation concepts can create a unique and individual customer experience. With PERFORM we create a coherent customer experience for Digital Retail by combining online and traditional offline retail to an integrated Omnichannel system addressing the following 4 research objectives: ? Develop sustainable business models for the Digital Retail sector. ? Examine approaches to increase the customer experience along the customer journey. ? Investigate how technologies can be used to provide innovative Digital Retail services and create a unique customer experience. ? Develop knowledge base on Digital Retail operations and analytics. We will assist the Digital Retail sector to realise valuable strategic options for local EU retailers related to the Single Digital Market. PERFORM builds an interdisciplinary network including various disciplines (such as technology, business and behaviour science) and will educate Early Stage Researchers. PERFORM provides a timely response to the increasing need from the retail sector for highly skilled graduates and researchers, which are highly sought after in industry and academia. We offer exciting career perspectives based upon existing and future job profiles within the digital retail industry. The research programme of PERFORM will develop new methods, concepts and technology implementations for Digital Retail. Both academic and non-academic participants of PERFORM will contribute to strengthening the Innovation Capacity in Europe.";3869128,44;3869128,44;H2020-MSCA-ITN-2017;/MSCA-ITN-ETN;DUBLIN CITY UNIVERSITY;IE;"LINNEUNIVERSITETET;FH OO FORSCHUNGS & ENTWICKLUNGS GMBH;UNIVERSITAT LINZ;RAIFFEISENLANDESBANK OBEROSTERREICHAG;AWS-INSTITUT FUR DIGITALE PRODUKTEUND PROZESSE GGMBH;TECHNISCHE UNIVERSITEIT EINDHOVEN";"SE;AT;DE;NL";;1;0;0;1;0;0 211901;765636;InDEStruct;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2017;H2020;Integrated Design of Engineering Structures;2018-04-01;2022-03-31;;This collaborative doctoral training programme provides a model for the development of technology leaders, enabling them to apply scientific methods from academia to interdisciplinary industrial design. The project is driven by the need for more efficient & lower emission engine systems. Heat exchangers in engines has been identified as a key enabling technology for low-emission power systems that is vital to the EU economy and is of great societal concern. Development of high-performance heat exchangers is a complex engineering challenge requiring academic contributions at the forefront of engineering science, which will enhance the EU’s competitiveness by delivering economically and environmentally improved products. Having identified charge air cooling as a key enabling technology for low-emission power systems, here we propose an integrated approach to doctoral training in the area of engineering design leading to four doctorates covering diverse aspects of their mechanical engineering: structural vibration, stress & thermal analysis, additive manufacturing (AM), multifunctional metamaterials, fatigue & materials development. This project brings together a consortium of industrial and academic partners in a novel and bespoke doctoral training programme that is multi-disciplinary in its content and inter-sectoral with regards to the employability of the technology leaders of tomorrow. The programme provides a coherent training platform that inherently nurtures technical, creative and entrepreneurial skills. The central theme of Engineering Design within the programme enables us to build a training structure which is technically broad yet scientifically rigorous, while having the academic depth expected of a doctoral programme. The programme provides mobility, industrial experience and academic foundations in an integrated manner that will uniquely equip our future technology leaders to contribute to high-value innovation within EU industry.;1093151,52;1093151,52;H2020-MSCA-ITN-2017;/MSCA-ITN-EID;VESTAS AIRCOIL AS;DK;UNIVERSITY OF SOUTHAMPTON;UK;;1;0;0;1;0;0 211553;765866;ACHIEVE;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2017;H2020;AdvanCed Hardware/Software Components for Integrated/Embedded Vision SystEms;2017-10-01;2021-09-30;;ACHIEVE-ETN aims at training a new generation of scientists through a research programme on highly integrated hardware-software components for the implementation of ultra-efficient embedded vision systems as the basis for innovative distributed vision applications. They will develop core skills in multiple disciplines, from image sensor design to distributed vision algorithms, and at the same time they will share the multidisciplinary background that is necessary to understand complex problems in information-intensive vision-enabled applications. Concurrently, they will develop a set of transferable skills to promote their ability to cast their research results into new products and services, as well as to boost their career perspectives overall. Altogether, ACHIEVE-ETN will prepare highly skilled early-stage researchers able to create innovative solutions for emerging technology markets in Europe and worldwide but also to drive new businesses through engaging in related entrepreneurial activities. The consortium is composed of 6 academic and 1 industrial beneficiaries and 4 industrial partners. The training of the 9 ESR’s will be achieved by the proper combination of excellent research, secondments with industry, specific courses on core and transferable skills, and academic-industrial workshops and networking events, all in compliance with the call’s objectives of international, intersectoral and interdisciplinary mobility.;2266907,76;2266907,76;H2020-MSCA-ITN-2017;/MSCA-ITN-ETN;AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS;ES;"IMASENIC ADVANCED IMAGING S.L.;UNIVERSITE CLERMONT AUVERGNE;UNIVERSITEIT GENT;UNIVERSITA DEGLI STUDI DI UDINE;UNIVERSIDADE DE COIMBRA;COMMUNAUTE D' UNIVERSITES ET ETABLISSEMENTS UNIVERSITE BOURGOGNE - FRANCHE - COMTE";"ES;FR;BE;IT;PT";;1;0;0;1;0;0 194375;645736;EVE;CLOSED;H2020-EU.1.3.3.;MSCA-RISE-2014;H2020;INNOVATIVE ENGINEERING OF GROUND VEHICLES WITH INTEGRATED ACTIVE CHASSIS SYSTEMS;2015-01-01;2017-12-31;;Innovation technologies in ground vehicle engineering require strong interdisciplinary and intersectoral investigations with an international dimension. In this context the project EVE proposes sustainable approach based on intensive staff exchange that leads to collaborative research and training between universities and industrial organizations from Germany, Belgium, Spain, Sweden, The Netherlands, South Africa, and the USA. The project includes basic and applied research, development design, experimentations, networking, and dissemination and exploitation activities. The research objectives are focused on the development of (i) experimental tyre database that can be used in the design of new chassis control systems and subjected to inclusion into Horizon 2020 pilot on Open Research Data, (ii) advanced models of ground vehicles and automotive subsystems for real-time applications, and (iii) novel integrated chassis control methods. It will lead to development and improvement of innovative vehicle components such as (i) an integrated chassis controller targeting simultaneous improvements in safety, energy efficiency and driving comfort, (ii) new hardware subsystems for brakes, active suspension and tyre pressure control for on-road and off-road mobility, and (iii) remote network-distributed vehicle testing technology for integrated chassis systems. The project targets will be achieved with intensive networking measures covering (i) knowledge transfer and experience sharing between participants from academic and non-academic sectors and (ii) professional advancement of the consortium members through intersectoral and international collaboration and secondments. The project EVE is fully consistent with the targets of H2020-MSCA-RISE programme and will provide excellent opportunities for personal career development of staff and will lead to creation of a strong European and international research group to create new hi-tech ground vehicle systems.;616500;571500;H2020-MSCA-RISE-2014;/MSCA-RISE;TECHNISCHE UNIVERSITAET ILMENAU;DE;"AKTIEBOLAGET SKF;SKF BV;UNIVERSITE DE TECHNOLOGIE DE COMPIEGNE;INSTITUTO TECNOLOGICO DE ARAGON;DSPACE DIGITAL SIGNAL PROCESSING AND CONTROL ENGINEERING GMBH;TENNECO AUTOMOTIVE EUROPE BVBA;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;UNIVERSITY OF SURREY;TECHNISCHE UNIVERSITEIT DELFT;CHALMERS TEKNISKA HOEGSKOLA AB";"SE;NL;FR;ES;DE;BE;UK";;1;0;0;1;0;0 209788;748752;Fluidblasto;CLOSED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Luminal pressure: a sculptor for mouse blastocyst self-organisation;2018-09-01;2020-08-31;;An important morphogenetic event of mammalian embryogenesis is the formation of a blastocyst with a fluid-filled cavity, blastocoel, and the establishment of three cell types essential for implantation. Morphogenesis of the blastocyst begins with the emergence of multiple nascent cavities, which progressively coalesce to form one cavity segregating the cavity-facing primitive endoderm from the epiblast within the inner cell mass. While cell-to-cell gene expression heterogeneity is well characterised during this lineage specification, little is known about the physical principles governing self-organized blastocyst morphogenesis and patterning. In particular, changes in fluid pressure, cell shape and polarity during blastocyst formation remain uncharacterized. In this project, I will study the roles of fluid cavities in coordinating tissue mechanics, polarity and lineage specification. I will establish a novel micropressure technique to quantify the growth of luminal pressure during blastocyst development. Combining micropipette aspiration with high-resolution live-embryo imaging, I will characterize the impact of fluid pressure on trophectoderm fate specification through dynamic changes in cell shape and adhesion, and cytoskeletal remodeling. To assess the impact of fluid pressure on inner cell mass, I will study if cavity expansion induces apical polarisation and enhances primitive endoderm differentiation in cavity-facing cells. Combining laser ablation with light-sheet microscopy, we will build a spatio-temporal map of intercellular forces in vivo during blastocyst development. We will further manipulate the cavity size to study if fluid pressure is functionally required and sufficient for driving lineage segregation. This interdisciplinary and quantitative study will establish the novel role of fluid cavities and elucidate their interplay with biochemical signaling within the multi-cellular self-organization process.;171460,8;171460,8;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;EUROPEAN MOLECULAR BIOLOGY LABORATORY;DE;;;;1;0;0;1;0;0 205416;722479;MEMO2;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2016;H2020;MEthane goes MObile - MEasurements and MOdelling;2017-03-01;2021-02-28;;"Mitigation of climate change is a key scientific and societal challenge and also a headline target of the EU2020 strategy. Strong reductions in greenhouse gas emissions are necessary to reach the global warming target agreed on at the 2015 United Nations Convention of Parties in Paris. Such emission reductions can only be achieved if sources are properly quantified and mitigation efforts are verified, but there are large discrepancies between official emission inventories and estimates derived from direct measurement of the air. MEMO2 will contribute to the EU2020 targets with a focus on methane (CH4), the second most important greenhouse gas after CO2 and one of Europe’s most important energy sources. CH4 emissions are a major contributor to Europe's global warming impact, but they are also a good target for climate change mitigation because of a rather short lifetime of 10 years (policy-maker compatible) and several sources offering possibilities of “no-regret” emission reduction (landfills, gas leaks, manure). However CH4 emissions are not well quantified yet. MEMO2 will bridge the gap between large-scale scientific estimates from in situ monitoring programs and the 'bottom-up' estimates of emissions from local sources that are used in the national reporting. MEMO2 will identify and evaluate CH4 emissions and support mitigation measures by I) developing new and advanced mobile methane measurements tools and networks, isotopic source identification, and modelling at different scales, and II) educating a new generation of “cross–thinking” scientists, which are able to effectively implement novel measurement and modelling tools in an interdisciplinary and intersectoral context. The 9 beneficiaries and 13 non-academic partners of MEMO2 offer a well–structured intersectoral training programme to equip young researchers with strong scientific and personal competencies, which will enhance their employability as well as European innovation capacity in the future.";3361290,84;3361290,84;H2020-MSCA-ITN-2016;/MSCA-ITN-ETN;UNIVERSITEIT UTRECHT;NL;"AKADEMIA GORNICZO-HUTNICZA IM. STANISLAWA STASZICA W KRAKOWIE;RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG;WAGENINGEN UNIVERSITY;RIJKSUNIVERSITEIT GRONINGEN;LUNDS UNIVERSITET;EIDGENOSSISCHE MATERIALPRUFUNGS- UND FORSCHUNGSANSTALT;UNIVERSITE DE VERSAILLES SAINT-QUENTIN-EN-YVELINES.;ROYAL HOLLOWAY AND BEDFORD NEW COLLEGE";"PL;DE;NL;SE;CH;FR;UK";;1;0;0;1;0;0 216343;801540;RESCUE;SIGNED;H2020-EU.1.3.4.;MSCA-COFUND-2017;H2020;Local Training Network on REgenerative medicine and Stem Cell technology in UtrEcht;2018-06-01;2023-05-31;;"With an aging population, a growing burden of chronic conditions, and rising healthcare costs in Europe, the need for organs, tissues, and personalized strategies for decision making in therapeutic choices has never been greater. Recent developments herald the promise of regenerative medicine and stem cell (RMSC) technology. However, for RMSC to fully capture its potential, a synergistic and multidisciplinary effort remains necessary to achieve essential scientific breakthroughs. There is thus a high demand for an excellent graduate program that trains a new brand of researcher who will successfully bring RMSC technology from bench to bedside and back. Such a researcher understands the needs and demands that exist in the clinic, the strengths and limitations of RMSC technology and its ethical and regulatory aspects, and has the entrepreneurial spirit to push their discoveries towards new applications. Therefore, the University Medical Centre Utrecht (UMCU) has initiated the RMSC-dedicated doctoral training programme RESCUE. RESCUE features an international, interdisciplinary and inter sectoral approach to train 29 highly skilled Early Stage Researchers (ESRs) to become the future leaders in RMSC research and implementation of RMSC technology. RESCUE brings together 31 principal investigators that are renowned experts in their fields, have ample experience with supervising PhD students and leading successful research groups. RESCUE is tightly connected with multiple international academic and private partner organisations, each providing complementary research or training. RESCUE enables UMCU to develop best practices in high quality training and research. The long-term ambition of RESCUE is to establish a strong and coherent network that connects highly skilled young researchers as well as established scientists, who will continue to inspire each other to excel in making discoveries in RMSC far beyond the funding period.";6069120;3034560;H2020-MSCA-COFUND-2017;/MSCA-COFUND-DP;UNIVERSITAIR MEDISCH CENTRUM UTRECHT;NL;;;;1;0;0;1;0;0 216042;771589;DEBATE;SIGNED;H2020-EU.1.1.;ERC-2017-COG;H2020;Debate: Innovation as Performance in Late-Medieval Universities;2018-08-01;2023-07-31;;The switch from parchment to paper had a fundamental impact on later medieval universities, equivalent to the shift to Open Access today, hindering some intellectual practices while encouraging others. The DEBATE project identifies a neglected genre of latin texts that flourished on paper, the Principia, which record the public confrontations between candidates (socii) for the title of doctor. These debates, imposed by university statutes throughout Europe as annual exercises linked to lectures on the Sentences (the medieval parallel to our PhD thesis), forced the candidate to reveal his innovative theories (sheets of papers were exchanged among the socii beforehand), display his erudition and prove his intellectual prowess before a large audience. The futuristic discussion usually exceeded the confines of one discipline and allowed the bachelor to indulge his interdisciplinary interests, employing science, theology, mathematics, politics, literature, and rhetoric in his polemics against his colleagues. Principia thus reveal the cutting edge method of fostering science in later medieval universities. The DEBATE team intends to identify new manuscripts, edit the texts, establish authorship for anonymous fragments and propose an interpretation that will help explain how innovation was a primordial target in medieval academia. Putting together all the surviving texts of Principia produced in various cultural contexts, this project will provide a wealth of material that will bring about a basic change in our understanding of the mechanism of the production of academic knowledge in the early universities all around Europe.The project is designed to promote erudition by combining a palaeographical, codicological, editorial and hermeneutical approach, aiming to open an advanced area of inquiry focusing on an intellectual practice that bound together medieval universities from different geographical and cultural regions: Paris, Bologna, Vienna, Prague, Krakow and Cologne.;1997976;1997976;ERC-2017-COG;/ERC-COG;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FR;;;;1;0;0;1;0;0 216034;771082;DRONETHICS;SIGNED;H2020-EU.1.1.;ERC-2017-COG;H2020;Emergent Ethics of Drone Violence: Toward a Comprehensive Governance Framework;2018-07-01;2022-06-30;;"The increasing use of armed, uninhabited aircraft (drones) is a serious political challenge with implications for security and justice worldwide. Drone technology is attracting high levels of investment, drones controlled remotely are becoming more numerous, and technological momentum toward drones controlled by artificial intelligence (AI) is building. Many human lives are at stake in this, so the violent use of drones continues to raise ethical questions. DRONETHICS will systematically address an urgent need to clarify the morality of ‘drone violence’, defined as violence involving a weapon system that is radically remote from its immediate user. Such remoteness is achieved through extreme physical distancing or the devolution of agency from humans to machines, so drone violence disrupts traditional expectations about war and a warrior’s exposure to risk. In turn, the disruptively innovative premise of this project is that such violence does not necessarily fall within the remit of the Just War framework according to which war is traditionally judged and governed. Moving beyond state-of-the-art Just War thinking, the project opens up an ethical inquiry into drone violence conceptualised as either war, law enforcement, interpersonal violence, or devolved (to AI) violence. An interdisciplinary research team, incorporating international relations, moral philosophy and computer science perspectives, will conduct rigorous analysis of documentary sources and engage closely with officials, drone operators, and roboticists. Through innovative exploration and application of alternative frameworks for governing violence, DRONETHICS will produce: the first integrated conceptual framework for explaining ethical concerns arising from current and potential forms of drone violence; concrete recommendations for policy-makers on how to manage this violence ethically; and a new normative vision for shaping the longer-term trajectory of drone violence for the good of all humanity.";1359348;1359348;ERC-2017-COG;/ERC-COG;UNIVERSITY OF SOUTHAMPTON;UK;;;;1;0;0;1;0;0 216341;801509;CoCirculation2;SIGNED;H2020-EU.1.3.4.;MSCA-COFUND-2017;H2020;CO-FUNDED Brain Circulation Scheme 2;2018-07-02;2023-07-01;;CoCirculation2 is a 5-year project aiming to invite experienced researchers to both academic and non-academic research performing organizations located in Turkey. Within this context, 100 experienced researchers of any nationality who wish to engage in incoming mobility and to spend a period of 24 months in Turkey will be able to apply for a fellowship. 4 calls for proposals will be published. The program will have a bottom-up approach. The evaluation and selection procedures as well as recruitment procedures are in line with the conditions in the European Charter and Code. CoCirculation2 is the follow up project of the “Co-funded Brain Circulation Scheme (Co-Circulation)”, which has been funded under the FP7-PEOPLE-2011-COFUND call. Compared to the current Co-Circulation program, Co-Circulation2 will bring the evaluation and selection process closer to recommendations in the Charter and Code, allow for secondments, improve the training offer for fellows and improve the financial and social conditions of the fellowships. CoCirculation2 offers transnational mobility, career development and personal training opportunities to the researchers. In line with the European Commission objectives, the project will contribute to the potential and future career perspectives of researchers in academy and industry while enhancing their international networking and interdisciplinary skills. CoCirculation2 will create a new cohort of Experienced Researchers who have acquired relevant scientific and transferable skills during their research project and other activities during their fellowship. These skills will prepare them for the next steps in their professional career, either in academia or in non-academia, and either in Turkey or beyond. Turkish and European Research Area as a whole will benefit from the contribution of the CoCirculation2 fellows to the research landscape. TÜB?TAK will contribute 55% of the total budget while European Commission is requested to co-fund 45%.;12390000;6195000;H2020-MSCA-COFUND-2017;/MSCA-COFUND-FP;TURKIYE BILIMSEL VE TEKNOLOJIK ARASTIRMA KURUMU;TR;;;;1;0;0;1;0;0 216359;810630;VALORTECH;SIGNED;H2020-EU.4.c.;WIDESPREAD-03-2017;H2020;ERA Chair for Food (By-) Products Valorisation Technologies of the Estonian University of Life Sciences;2018-07-01;2023-06-30;;"Advanced food processing technologies, minimum waste and maximum utilisation of raw material used as well as valorisation of by-products constitute a highly relevant range of topics in the EU and worldwide. These are matters that the University of Life Sciences (Eesti Maaülikool, EMU) has been dealing with for long from various angles and perspectives. However, to realise the full potential of EMU in this domain, structural changes are needed to bring various related competences under a unified umbrella as well as to cover several gaps hindering further development. Therefore, the main objective of the current project is to establish a new ERA Chair for Food (By-) Products Valorisation Technologies (VALORTECH), and recruit a top level researcher/research manager (ERA Chair holder) to lead this interdisciplinary, inter-unit entity, formed based on a joint effort by the Institute of Agricultural and Environmental Sciences and the Institute of Veterinary Medicine and Animal Sciences of EMU. The new Chair is expected to considerably improve the research and innovation performance of EMU and conduct forefront research that would create significant benefits for both Estonia, Europe and beyond. Efficient dissemination and exploitation of research results is an issue of key importance in the context of the ERA Chair´s action plan. In addition to targeting the international research community and providing input to policy development, facilitating knowledge transfer to industry is at particular focus. The R&D to be carried out in the VALORTECH Chair is strongly connected with both the national and regional Smart Specialisation strategy, in the context of which efficient use of resources and related development of health-promoting (functional) food are among key priorities. The demand for advanced R&D services in the VALORTECH fields from the side of the industry currently exceeds the capacity of EMU to provide such services.";2498625;2498625;H2020-WIDESPREAD-03-2017-ERAChairs;/CSA;EESTI MAAULIKOOL;EE;;;;1;0;0;1;0;0 216289;797386;ArcNames;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Individuals, social identities and archetypes – the oldest Scandinavian personal names in an archaeological light;2019-03-01;2021-02-28;;"This project sets out to investigate the relation between personal names, social identities and social status in Scandinavia, ca. 300 - 800 AD. The project is called ArcNames and it aims to rethink the evidence of Late Iron Age and Viking Age personal names and their contexts by putting them into an up-to-date archaeological framework. The ArcNames project has two main objectives. First, it will create a better understanding of individual naming and the construction of personal and social identities in the Scandinavian Late Iron Age and Viking Period mainly by investigating the correspondence between names and archaeological evidence relating to identity. Therefore, the first part will assess the motives expressed in personal names and how these correspond with identities expressed in iconography, burial assemblies and runic inscriptions. Secondly, these issues will be evaluated in relation to the archaeological understanding of status and landholding, especially through a discussion of the use of personal names in place names and runic inscriptions. The second part thus will investigateshow personal names occuring in place names express status and ownership structures and help to understand the social aspects of Late Iron Age and Viking period settlement patterns. A prominent theme in the investigations will be the perceptions of women and land ownership or power structures in relation to gender. The project will work to build an interdisciplinary research environment around onomastics and archaeology at the University in Bergen in connection with the new establishment of the Norwegian Language Collections here. At the same time, it contains a plan to train the fellow in archaeological research skills, university teaching and research management.";208400,4;208400,4;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;UNIVERSITETET I BERGEN;NO;;;;1;0;0;1;0;0 214163;795614;SPECTRE;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;SPEciation and dynamiCs of TRace Elements;2018-06-01;2020-08-31;;Ever-increasing production of waste requires new provisions for waste management to ensure sustainable development. The use of organic waste (OW) as fertiliser is a promising route but may represent an environmental pathway for flows of contaminants. In Europe and across the world, antibiotic resistance genes (ARGs) and trace elements (TEs) are seen as two major threats to environmental and human health. Overcoming the lack of knowledge of the role of TEs as a selective agent in the proliferation of ARGs is a major scientific challenge today. The overall objectives of SPECTRE are to (i) link the spatial distribution of TE speciation in OWs with the development of resistance at microscale and (ii) to assess the fate of TEs and ARGs in the OW-soil-plant system. During the SPECTRE project, I will take full advantage of my time at the interdisciplinary Future Industries Institute (FII, University of South Australia) to acquire new skills in molecular biology to screen interesting bacterial community members and (ii) increase my expertise in TE speciation by harnessing the analytical power of a spectroscopic cutting-edge technique. This training will position me as a leader in Europe in this rapidly advancing field. Furthermore, the unique FII environment will enable me to develop my transversal skills and gain experience in the management of public-private research partnerships. Knowledge transfer (blended learning, hands-on training, training-through-research) is essential to broaden the scope of my research as well as reinforce my future career prospects. Beyond the publication of scientific papers, I will make a particular effort to ensure that the results are widely disseminated to different audiences: schoolchildren (social networking, video link facilities), school teachers (professional development), end-users in the agro-environmental sector (workshop, seminar) and MSc students (e-learning).;204025,5;204025,5;H2020-MSCA-IF-2017;/MSCA-IF-GF;CENTRE DE COOPERATION INTERNATIONALE EN RECHERCHE AGRONOMIQUE POUR LEDEVELOPPEMENT - C.I.R.A.D. EPIC;FR;;;;1;0;0;1;0;0 214169;796388;ECOMAT;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Encapsulation and contacting of two-dimensional materials;2018-06-01;2020-05-31;;"Two dimensional materials such as graphene and transition metal dichalcogenide (TMDC) are very sensitive to surface adsorbates and thus require proper encapsulation. In addition, functional devices based on those materials, like transistors, diodes or electro-optical modulators require high-k gate dielectrics to be deposited on top of the material. However, the deposition of high quality dielectric layers ontop of 2D materials is very challenging due to their inert surface. The project ECOMAT addresses the important challenge of depositing high-k dielectrics on top of 2D materials. In particular, the experienced researcher Dr. Barbara Canto will explore different routes to encapsulate graphene and MoS2, which is the most explored TMDC material, with different high-k dielectrics using a combination of atomic layer deposition and surface functionalization using seed layers. The key control parameters for those layers are dielectric constant, breakdown voltage, charge traps, minimal thickness achievable, and gas barrier properties, which will be characterized by electrical and spectroscopic methods. Finally a new route for fabricating low-resistive edge contacts to MoS2 will be explored, building up on encapsulated MoS2 layers. This contacting scheme is expected to significantly reduce contamination of the MoS2 layer during processing, while offering low-resistive contacts and thus will significantly increase the performance of electronic device based on MoS2. This interdisciplinary research activity builds up on the experience of Dr. Canto in the field of material science and physics and utilizes the infrastructure and knowledge at AMO on high-k dielectrics and electronic devices.";159460,8;159460,8;H2020-MSCA-IF-2017;/MSCA-IF-EF-SE;GESELLSCHAFT FUR ANGEWANDTE MIKRO UND OPTOELEKTRONIK MIT BESCHRANKTERHAFTUNG AMO GMBH;DE;;;;1;0;0;1;0;0 213420;765290;MIRA;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2017;H2020;Microbe induced Resistance to Agricultural pests;2017-12-01;2021-11-30;;Plants are intimately associated with a diversity of beneficial microorganisms in their root zone, some of which can enhance the plant’s resistance to insect pests. Thus, the use of Microbe-induced Resistance (MiR) to reduce pest losses in agriculture has emerged as a highly promising possibility to improve crop resilience and reduce use of harmful pesticides. European companies have therefore started to develop and market beneficial microbes. However, MiR appears to be strongly context-dependent, with reduced benefits under certain biotic and abiotic conditions and in some crop varieties. Further, it is a challenge to deliver and ensure stable associations of beneficial microbes and plants, and avoid undesired effects on beneficial insects. Thus we absolutely must improve our understanding of MiR mechanisms and context-dependency, in order to improve context stability of MiR and promote the use of MiR for crop protection. Our MiRA project will train 15 ESRs in basic and applied research on context-dependency of MiR, mechanisms, and impacts on plant performance and other biocontrol organisms. We will use this understanding to improve our ability to predict the effectiveness of MiR under different conditions, to select plant and microbial strains with improved context-stability, and to develop better methods for the formulation of microbial inoculants and their application in agriculture. Finally, we will analyse economic prospects and constraints for MiR development and use. To achieve these goals, we have assembled a consortium of 11 academic institutions and 6 companies, including microbial inoculant producers and agricultural advisors, with complementary skills in basic and applied research and innovation. Our ESRs will be trained within this multi-sectoral interdisciplinary network for a future career in research, product and service development in European horticulture and agriculture, pushing boundaries in European research and innovation.;3936528,36;3936528,36;H2020-MSCA-ITN-2017;/MSCA-ITN-ETN;KOBENHAVNS UNIVERSITET;DK;"THE JAMES HUTTON INSTITUTE;KOPPERT BV;KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW;AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS;UNIVERSITE DE NEUCHATEL;RHEINISCHE FRIEDRICH-WILHELMS-UNIVERSITAT BONN;FRIEDRICH-SCHILLER-UNIVERSITAT JENA;UNIVERSITEIT UTRECHT;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;INOQ GmbH";"UK;NL;ES;CH;DE;FR";;1;0;0;1;0;0 214093;788651;KurdishWomen;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;From Kurdistan to Europe: Kurdish Literary, Artistic and Cultural Activism by Kurdish Women Intellectuals;2018-06-01;2020-05-31;;Kurdish women have been involved in film production, radio broadcasts and exhibitions, as well as in the production of a substantial number of books, journals and other publications in both Kurdish and national languages of the European states. However, the aesthetic and intellectual production of Kurdish women, which leads to the empowerment of women and advancement of gender equality in the Kurdish diaspora, has not been the subject of any notable research yet. By going beyond stereotypical portrayals of Kurdish women, presented as either victim of honour-based violence or someone who suffers violent conflict, this research will deal with the gendered experiences of Kurdish diaspora from the four regions of Kurdistan (Iran, Iraq, Syria and Turkey) in terms of the growth of aesthetic, literary and cultural practices by migrant Kurdish women in five nation-states (Belgium, France, Sweden, Germany, UK) along with their impacts on larger societal debates within a comparative approach. It will also investigate the varying migrant incorporation regimes of selected European countries, including the impacts of the recent influx of Syrian Kurdish refugees. It includes ethnographic fieldwork, along with multi-sited research techniques carried out in the capitals of selected European states, data collection of both primary sources (creative, literary and cultural productions) and secondary sources (EU documents, annual progress reports, press releases). This study has a potential to encourage the maximization of networks of educational and intellectual revitalization in European states. It will also encourage other Kurdish migrant women to become factors of change and reach others. This is an interdisciplinary project aiming to fill in a significant gap in the relevant socio-political, gender, migration and cultural academic studies and policy debates within the European Research Area. It is in line with the EC’s strategy for gender equality provision.;183454,8;183454,8;H2020-MSCA-IF-2017;/MSCA-IF-EF-CAR;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;UK;;;;1;0;0;1;0;0 214114;792809;WHEREAL;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;World Heritage and East Asian Literature – Sinitic writings in Japan as Literary Heritage;2018-06-01;2021-05-31;;In the last 20 years, world heritage and world literature have drawn much attention because they represent a convenient framework for visualising and promoting a certain numbers of selected ‘items’ acknowledged as the best achievements of human creativity, in response to a growing interest about foreign cultures. However, the concepts of world heritage—especially the recent declaration of intangible cultural heritage (ICH)—and world literature have been harshly questioned: Is it correct to delegate to an international community that is identified with the cultural elites of developed countries the power to judge and “edit the cultural diversity of the world” such as UNESCO”s list of ICH, or to arrange and create a new canon of “what is literary and what is not” such as in anthologies of world literature? These questions are tied to problems of the ownership of cultural heritage and of authorship of certain literary works that are translated from peripheral languages to hegemonic, international ones. Regarding these problems, the discourses of East Asia and Japan are interesting objects of study not only because they are both ‘peripheral’ from the traditional, Eurocentric point of view but also because their cultural and literary heritage is often older and richer than that of many European countries. This action will allow the candidate to apply an interdisciplinary approach to merge the different debates on ownership and authorship, and to formulate a new definition of ‘literary heritage’ that presents an alternative to the dichotomy of tangible/intangible. The case study will focus on the role of Sinitic writing (jp.: kanbun) in pre-modern Japan as part of the shared cultural heritage of East Asia and its historical development, reception, diffusion and eventual abandonment. This research will stimulate the dialogue on the role of literary heritage among multicultural societies with shared traditions and languages, such as East Asia and the European Union.;280683;280683;H2020-MSCA-IF-2017;/MSCA-IF-GF;UNIVERSITA CA' FOSCARI VENEZIA;IT;;;;1;0;0;1;0;0 196068;661198;Amicrex;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Development of a Microwave Assisted Cell Disruption of Biomass and Extraction of Valuable Compounds;2015-05-01;2019-09-17;;"The combination of biomass valorisation, process intensification and green technology is an attractive research challenge for the European Community being in line with the “Resource-efficient Europe” flagship initiatives by optimizing the use of material, energy resources and gaining valuable products with lower impact on our environment and health. The AMICREX project accepts this challenge and aims to develop an integrated process design for future industrial implementation, where by-products from agro industrial processes (e.g. carrot peels) can be valorised by recovering high- value nonpolar components (e.g. carotenoids, well recognized natural pigments and widely used in the food and cosmetic industries) through a microwave intensified microemulsion extraction process. The AMICREX concept can be extended to address the challenges proposed by extraction of nonpolar metabolites, especially carotenoids, from other renewable biomass sources (e.g. Microalgae). The key aspects of the proposed technology are 1) avoid the use of hazardous organic solvents in nonpolar compounds’ extraction by using microemulsion as extraction media, and 2) improve extraction kinetics by microwave cell disruption method in order to liberate intracellular compounds and make them available for the subsequent extraction process. The research will first focus on the evaluation on the laboratory scale microwave cell disruption and subsequent microemulsion extraction processes of the characterized biomass. Based on the so obtained process and system specifications the small scale process is aimed to be turned into an industrial design concept through process modeling and simulation. The satisfactory implementation of the project will be achieved by filling the gap between multidisciplinary fields of natural sciences and engineering. Moreover, the interdisciplinary scenario between biomass cell disruption, extraction process and microemulsion technology will be established.";171460,8;171460,8;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.;DE;;;;1;0;0;1;0;0 195682;658900;EPIMAIZE;CLOSED;H2020-EU.1.3.2.;MSCA-IF-2014-GF;H2020;Understading the Maize Epigenome and its Role in Development;2015-08-01;2017-07-31;;"Phenotypes are largely determined by genetic factors. However, a given genotype can give rise to very distinct phenotypes, as exemplified by the diversity of cell types in multicellular organisms. This phenotypic plasticity results from epigenetic changes; that is, reversible modifications to the DNA molecule and its associated proteins that modulate gene expression patterns. Epigenetic changes are critical to the establishment of developmental programs, but also to adjust transcription in response to the environment. The latter is particularly important for plant adaptation: owing to a sessile (immobile) lifestyle, plants cannot run away from adversity, and thus adapt to their environment by tuning gene expression in response to changing conditions. Most epigenetic information is erased from one generation to the next, so that new organisms start their life cycle with a “fresh” potential. However, there are instances in nature of heritable epigenetic marks that can be transmitted to the next generation. Thus, owing to their role in shaping gene expression, and the potential for heritable changes, epigenetic factors are of great interest for plant breeders, in their quest for adaptable, high yielding phenotypes. Most of our current understanding of epigenetic processes in plants has been developed in Arabidopsis, a key model system. However, the Arabidopsis epigenome is rather idiosyncratic, and this knowledge might translate poorly to crops. Here, we will use an interdisciplinary approach combining original genetic materials and bioinformatics to analyze epigenetic regulatory pathways in maize, with a focus on reproductive development. Maize is an important model plant, with a large and dynamic epigenome much more typical of crops. It is also a crop of great economic importance. Better understanding the epigenome of maize will open the door to the manipulation of key agronomic traits, including reproductive development, which is under strong epigenetic influence.";178603,2;178603,2;H2020-MSCA-IF-2014;/MSCA-IF-GF;INSTITUT DE RECHERCHE POUR LE DEVELOPPEMENT;FR;;;;1;0;0;1;0;0 207073;734931;MILEAGE;SIGNED;H2020-EU.1.3.3.;MSCA-RISE-2016;H2020;Microelements in Life Expectancy and Aging;2017-05-01;2021-04-30;;"Increased longevity with a high quality of life is desirable not only for personal life-satisfaction but also for reducing healthcare costs and for increasing the socioeconomic contributions of individuals in countries with ageing population demographics. Lifelong lifestyle has an important impact on health status in older age and adequate nutrition plays a key role in maintaining cellular functions within normal limits. Microelements such as zinc (Zn) and copper (Cu) are essential for life and are involved in the normal functioning of thousands of proteins. The dysregulation of these metals leads to perturbed homeostasis, disease and diminished quality of life. In this study, the molecular mechanisms by which ageing affects Zn and Cu absorption and excretion will be determined, and the consequent impact on metal flux and transport kinetics will be expressed by mathematical modelling. The project output will include a predictive model for the impact of ageing on Zn and Cu homeostasis, informing intervention with dietary advice or supplementation to improve longevity. The consortium combines intersectoral and interdisciplinary expertise from 3 EU and 2 partner countries with established links and clear potential for knowledge exchange and transfer of skills. The consortium objectives are: 1. To determine the impact of dietary Zn and Cu on the microbiota and also age-related changes in the microbiota composition on the absorption of Zn and Cu. 2. To understand the influence of senescence on the regulation of Zn and Cu flux into and out of key cells controlling their homeostasis (gut mucosal cells, pancreatic acinar cells and hepatocytes) and its impact on the expression of related genes such as transporters. 3. To determine how senescence affects the transporter proteins, channels and chaperones involved in regulating Zn and Cu trafficking through the key absorptive and excretory cells affecting body metal homeostasis.";864000;864000;H2020-MSCA-RISE-2016;/MSCA-RISE;UNIVERSITE DE PICARDIE JULES VERNE;FR;"THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN;INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE;LIMITED LIABILITY COMPANY RESEARCH AND PRODUCTION ENTERPRISE I.F. LAB";"UK;FR;UA";;1;0;0;1;0;0 204126;681808;CIL2015;SIGNED;H2020-EU.1.1.;ERC-CoG-2015;H2020;Dissecting the cellular mechanics of contact inhibition of locomotion;2016-09-01;2021-08-31;;Our aim is to dissect the mechanisms of contact inhibition of locomotion (CIL), a process whereby migrating cells collide and repel each other, as it is now clear that CIL is pivotal to understanding embryogenesis and pathologies such as cancer. We have developed an in vivo model using Drosophila macrophages (hemocytes), along with novel analytical tools, to examine the contact inhibition response in cells during development. We therefore have an unprecedented opportunity to address CIL in a genetically tractable organism within a physiologically relevant setting. This model has revealed that a precisely controlled CIL response is a significant driving force behind the acquisition of embryonic patterns, and recent data show that this precision requires a series of synchronized changes in cytoskeletal dynamics. Our central hypothesis is that key to this cellular ‘dance’ is mechanosensation of the collision, which integrates subsequent signaling mechanisms to choreograph the steps of the contact inhibition process. The first part of this proposal will elucidate the molecular mechanisms controlling CIL by exploiting our unique ability to live image and genetically dissect this process in Drosophila. We will also take an interdisciplinary approach to elucidate the mechanical aspects of the response, which will allow us to examine the feedback between signaling pathways and the physical forces of the CIL response. We will subsequently extend our detailed understanding of the CIL process, and our novel set of analytical tools, to mammalian cell types and model systems. This will allow us to develop new assays to directly probe the mechanics of CIL and begin to investigate the function of this underexplored process in other cell types. This in depth knowledge of the response places us in the best position to extend our understanding of CIL to new physiologically relevant scenarios that in the future will impact on human health.;1993802,59;1993802,59;ERC-2015-CoG;/ERC-COG;KING'S COLLEGE LONDON;UK;;;;1;0;0;1;0;0 216230;788607;SNICC;SIGNED;H2020-EU.1.1.;ERC-2017-ADG;H2020;Studying Secondary Nucleation for the Intensification of Continuous Crystallization;2018-07-01;2023-06-30;;"Many products in the chemical, food and pharmaceutical industry are produced as powders through a crystallization process. Continuous crystallization has been for decades the process of choice for large-scale production, for instance of sugar, table salt, adipic acid, and has become more recently a key component of the new paradigm, i.e. the continuous manufacturing of active pharmaceutical ingredients. All product crystals of continuous crystallization processes are formed through secondary nucleation, which is both ubiquitous and elusive. Research has left several key questions unanswered, such as about where and how secondary nuclei are formed, either from the parent crystal due to collisions or from the solution layer around it due to fluid shear; or about the rate at which secondary nuclei are generated, with which properties, and under which conditions; or, also, about the coupling between the parent crystal microscale and the collective behavior of the ensemble of crystals suspended in a specific continuous crystallizer. The project SNICC intends to unveil the microscale mechanisms of secondary nucleation, and to bring its scientific understanding to a level where it can be exploited to model, design, operate, optimize and control continuous crystallization processes at any desired scale. It aims at creating a comprehensive knowledge about secondary nucleation at the microscale, applicable to any type of compound, and at establishing guidelines for the intensification of continuous crystallization, based on the use of newly developed full models of different types of continuous crystallizers. This will have a major impact on both the science of crystallization and the related industrial processes. Building on the recognized experimental and theoretical expertise on crystallization at all relevant scales of the PI and his lab, a team consisting of 4 PhD students and 2 postdocs will work for five years on this challenging, interdisciplinary project.";2500000;2500000;ERC-2017-ADG;/ERC-ADG;EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH;CH;;;;1;0;0;1;0;0 216031;770562;CRISEA;SIGNED;H2020-EU.3.6.1.3.;ENG-GLOBALLY-06-2017;H2020;Competing Regional Integrations in Southeast Asia;2017-11-01;2020-10-31;;"'The project Competing Regional Integrations in Southeast Asia (CRISEA) brings together Southeast Asian (SEA) and European researchers with 3 objectives. 1. Research. Our previous research shows that SEA is open to multiple forces that drive regional integration through competition for resources and legitimacy. In the current crisis of legitimacy for globalisation, SEA's competing regional integrations present challenges for its people and for ASEAN's framework-building project. We analyse these in sectorally-themed work packages on 'arenas of competition': the environment, the economy, the State, the identity of SEA's people, and the Region. Using an interdisciplinary micro-macro method of analysis, we ask in each case how ASEAN-led regional integration is – and is seen by SEA's people as – part of the problem or part of the solution. CRISEA engages with the work programme's concern with 'what ‘region’ means to the peoples of these countries within and beyond the ASEAN context'. Closely aligned with the 2015 Joint Communication on EU-ASEAN relations, it enhances the EU's understanding of 'the Asia-Pacific as a strategic region for Europe'. 2. Policy relevance. CRISEA's research programme was developed for its relevance to EU policy on ASEAN and its member states. Its dissemination strategy innovates by creating mechanisms for dialogue with a targeted audience of policy makers, stakeholders and the public in Brussels and SEA, using briefing sessions, workshops, press coverage, film, public lectures and policy briefs. 3. Networking and capacity building for the European Research Area. Leveraging existing networks of EU-SEA cooperation – the unique EFEO network of 10 field centres in SEA, the IDEAS and SEATIDE projects, EUROSEAS, ASEF – we reinforce the ERA through coordinated academic exchange, joint research and results delivery. Our consortium engages western European and ASEAN scholars with emerging expertise in southern and eastern Europe.'";2500000;2500000;H2020-SC6-ENG-GLOBALLY-2017;/RIA;ECOLE FRANCAISE D'EXTREME-ORIENT;FR;"INSTITUTO SUPERIOR DE CIENCIAS SOCIAIS E POLITICAS;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;MANDALAY UNIVERSITY;CHIANG MAI UNIVERSITY;UNIVERSITAET HAMBURG;ATENEO DE MANILA UNIVERSITY;YAYASAN PUSAT PENGKAJIAN MALASAH STRATEGI DAN INTERNASIONAL INDONESIA;UNIVERSITA DEGLI STUDI DI NAPOLI L'ORIENTALE;UNIVERSITETET I OSLO;UNIWERSYTET LODZKI;VIEN KHOA HOC XA HOI VIET NAM;UNIVERSITY OF MALAYA";"PT;UK;MM;TH;DE;PH;ID;IT;NO;PL;VN;MY";;1;0;0;1;0;0 214872;787180;NEWSENs;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;eNergy nEutral Wireless SEnsor Networks;2019-05-01;2021-04-30;;Urbanisation is a significant worldwide trend that Smart City technologies aim to address through prolific smart sensing and intelligent actuation and control. However, the high battery replacement costs of wireless sensors impede innovation and long-term deployments. This project aims to alleviate this problem through a novel system architecture that is powered by cheap, renewable solar energy and that uses state-of-the-art radio frequency (RF) wireless power transfer (WPT) technologies. More specifically, this project will study the technical, practical, and economic aspects of eNergy nEutral Wireless SEnsor Networks (NEWSENs) that comprise of solar-powered central access points acting as RF-energy and information hubs serving a collection of RF-powered wireless sensor devices. The electromagnetic waves used to wirelessly communicate data information with the small electronic devices and sensors will therefore also be used to power them up through a rectification circuitry. When inter-connected, these wireless devices form networks capable of supporting various Smart City applications. To demonstrate this new system architecture, a proof-of-concept test-bed will be assembled and used to validate the project’s technical results and support further prototyping and commercial exploitation. This interdisciplinary effort will utilise advanced mathematical models, multi-objective optimisation algorithms, and renewable energy economics. The project will coordinate inter-sectoral (telecommunications and renewable energy) R&D at the KIOS Research and Innovation Centre of Excellence and the FOSS Research Centre for Sustainable Energy, both of which operate under the University of Cyprus. These efforts will be further accentuated by an industrial secondment at RIO SYSTEMS, a fabless semiconductor company in Israel, thus enhancing EU competitiveness in green Smart City solutions and WPT technologies while expanding research collaboration with SMEs in neighbouring countries.;151648,8;151648,8;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;UNIVERSITY OF CYPRUS;CY;;;;1;0;0;1;0;0 215164;793482;ALPINE;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Ultrastructural analysis of phosphoinositides in nerve terminals: distribution, dynamics and physiological roles in synaptic transmission;2018-04-01;2020-03-31;;Phosphoinositides (PIs) are minor components of cell membranes, and play important roles in cellular functions. In chemical synapses in mammalian brain, each PI distributes different subcellular areas in nerve terminals, and cooperate with many proteins to regulate synaptic transmission machinery. To understand how PIs regulate synaptic transmission, the ultrastructural distribution pattern and dynamics of PIs at nerve terminals are crucial because PIs may functionally interact with proteins at domains of nano-meter ranges called active zones (AZs) or peri-AZs. However, their ultrastructural distribution and dynamics in nerve terminals are poorly investigated because of some technical difficulties. This research project aims to investigate (1) the ultrastructural distribution of PIs at AZs and peri-AZs in nerve terminals, (2) co-localization of PIs with presynaptic proteins related to synaptic transmission, (3) the ultrastructural dynamics of PIs and PI-protein coupling during synaptic transmission, and (4) the physiological roles of PI-protein couplings in synaptic transmission, using electron microscopic and electrophysiological techniques combined with optogenetics and biochemical tools. These highly-interdisciplinary approaches will unveil the physiological roles of PIs and PI-protein couplings in synaptic transmission, and is expected to give a fundamental breakthrough in understanding mechanisms of synaptic transmission.;178156,8;178156,8;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;Institute of Science and Technology Austria;AT;;;;1;0;0;1;0;0 215308;794982;2DSTOP;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Spin transport and spin-orbit phenomena in 2D materials;2019-03-01;2021-02-28;;We live in a technological world where usage of electronic devices for information technology is an integral part of everyday life. Present and future technological progress requires miniaturization of such devices, continuous improvement of their performances and decreasing of energy consumption. Spintronics, a growing research field based on the manipulation of the spin of the electrons, offers devices that fulfil these needs. However, a new generation of proposed spintronic devices are yet to be realized due to the lack of a tuneable spin transport channel. The major obstacle to build such channel is that the transport and the manipulation of spins (which require weak and strong spin-orbit coupling, respectively) in the same material are mutually exclusive. 2DSTOP addresses this problem by exploiting the unconventional spin-dependent properties of the transition metal dichalcogenides. In these two dimensional (2D) layered materials, electrically tuneable spin transport in the presence of strong spin-orbit coupling is theoretically predicted. 2DSTOP envisions the experimental realization of such predictions. Combining these materials with other 2D materials such as graphene and hexagonal boron nitride, this proposal plans to investigate not only the spin transport, but also some of the exotic spin-orbit-related phenomena. This way, the project aims at acquiring scientific knowledge with potential technological applications to be useful for both academia and industry. Moreover, the ultimate goal of 2DSTOP is to offer high-quality interdisciplinary research training for an aspiring young researcher helping him to build a promising scientific research career.;170121,6;170121,6;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;Asociacion - Centro de Investigacion Cooperativa en Nanociencias - CIC NANOGUNE;ES;;;;1;0;0;1;0;0 215157;793405;STiMUL;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Controlled Space-Time dynamics in nonlinear Multimode fiber with gain for the next generation of high power Ultrafast fiber Lasers;2019-01-01;2020-12-31;;"With the advent of ultrashort light pulses of picosecond/femtosecond durations, numerous novel applications and potential capabilities have emerged. However, ultrashort fiber laser must operate in a nonlinear propagation regime with a complex balance among gain, spectral filtering, dispersion and nonlinear broadening. Furthermore, all current families of ultrafast lasers are based on single mode fibers (SMFs) and these have now reached limits in their application domains because of their inherent limited peak power handling capability. In order to overcome the aforementioned barrier for ultrafast fiber lasers, and enhance their operational range, I suggest to replace single mode fibers by multimode fibers. The main goal of this proposed MSCA Individual Fellowship is therefore to develop new ideas for the mode locking of lasers based on multimode gain fiber by controlling their spatio-temporal complex dynamics, and then to demonstrate generation of ultrashort light pulses with high average power and high peak power. The nonlinear coupling among the fiber modes can self-maintain a high degree of spatial coherence while permitting a high degree of temporal coherence with the locking of the modes on a common group delay. I propose to explore multimode space-time soliton propagation and beam nonlinear “self-cleaning” in amplifying rare-earth-doped multimode fiber and in multimode fiber laser. I believe that this could lead to the new building blocks of high power picosecond or femtosecond fiber lasers. XLIM is an interdisciplinary institute, hosting various fields of research. It is recognised as one of the top institutions in photonics and micro-electronics, and since 2011 has been considered as a “Laboratoire d’Excellence” by the French government. XLIM can therefore provide for an excellent environment in which I can conduct the proposed research while also achieving the required training, communication and dissemination objectives of the MSCA Fellowship.";185076;185076;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;UNIVERSITE DE LIMOGES;FR;;;;1;0;0;1;0;0 215623;798255;VISSATO;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Visual Search and Cognitive Control of the Speed-Accuracy Trade-off;2018-09-01;2020-08-31;;The visual environment in our daily life contains many objects, yet only a few of them are relevant for our behavior. In recent decades, our understanding of how we are able to find relevant objects has made substantial progress, in terms of both behaviour and its underlying neural basis. This progress is mainly based on the visual search paradigm where participants are asked to find a target object among non-target objects on a computer screen. Despite this progress, an important aspect of visual search has been neglected, the cognitive control of the ubiquitous speed-accuracy trade-off (SAT, i.e. we are likely to miss targets if we aim for fast responses). We can exert this control depending on many factors (e.g. motivation, situational context, etc.) and its flexibility undoubtedly contributed to our survival as a species. Despite this importance, few studies have investigated cognitive control of SAT in visual search. VISSATO aims to close this gap by employing a set of highly interdisciplinary research lines with experimental and computational modeling techniques. VISSATO will also draw on recent progress on SAT in the related field of perceptual decision making. This field typically examines how we make decisions about perceptual characteristics of single objects (e.g. the motion direction of noisy motion patterns). VISSATO will develop a novel visual search task which allows us to tap into cognitive control of SAT and conduct EEG studies with this task. VISSATO will also develop novel biophysical models of these experiments, testing different hypotheses about the control mechanisms. Using the latest advances in Bayesian model evaluation (including EEG source reconstruction) VISSATO will determine which of these novel models best explains the empirical data, thereby providing strong evidence on how the cognitive control of SAT in the processing of visual scenes is implemented in the brain.;195454,8;195454,8;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;THE UNIVERSITY OF BIRMINGHAM;UK;;;;1;0;0;1;0;0 215794;800204;VEILA;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Identifying the source of unknown volcanic eruptions in Late Antiquity;2018-11-01;2020-10-31;;Volcanism has shaped the human trajectory as a result of the regional impacts of ash deposition and through global climate change caused by stratospheric veils of volcanic sulphate aerosols. Volcanic forcing of climate is suspected to be implicated in centennial scale climatic cooling during the Common Era, notably in triggering the Little Ice Age (LIA, circa 1300-1850 CE), and the shorter but cooler Late Antique Little Ice Age (LALIA, circa 530-680 CE). The latter episode would have contributed to major societal reorganisations that occurred across Eurasia, including the rise and demise of empires, migrations and political upheavals. The LALIA coincides with a series of large volcanic eruptions of unknown source, only identified by sulphur-rich horizons in polar ice cores, left by aerosols trapped in the ice after dispersal through the high atmosphere. This project aims to locate the volcanic sources of these unknown 6th and 7th century eruptions, by characterising and correlating their geochemical fingerprints in global archives, including Antarctic and Arctic ice cores and equatorial lake sediment cores. An interdisciplinary approach at the interface of glaciology, tephrochronology, dendrochronology, and climatology will be used to extract and analyse micrometric particles of far-travelled ashes and to identify correlations between different the samples and potentially to identify the source. The results of the proposed research will provide methodological advances of wider interest to tephrochronologists, and will facilitate modelling of the climate impacts of these eruptions. The outputs will provide a better understanding of the role of volcanism in centennial scale climate cooling during the Common Era, and inform the extent to which volcanism and associated climate forcing played a role in Eurasian history in the Late Antique period. They will also be relevant to understanding the potential impacts of future temporal clustering of climate-forcing eruptions.;183454,8;183454,8;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;UK;;;;1;0;0;1;0;0 215638;798397;MULTIPROB;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Multi-photon probing of complex open quantum systems;2018-11-01;2020-10-31;;In this Marie Sklodowska-Curie action we explore the prospects of controlled multi-photon scattering processes as a probe of the nonlinear interactions and the dynamics of complex open quantum systems. The core of the project builds around the development of novel analytical and numerical tools to model complex scattering processes under correlated noise and dissipation. The project is thus mainly theoretical, but it is also interdisciplinary and focuses on problems and setups that admit immediate experimental implementations in a variety of state-of-the-art platforms, such as superconducting qubits coupled to microwave photons in transmission lines or quantum emitters coupled to photonic crystal waveguides. Moreover, the techniques and ideas that we will develop should be essential for the understanding and control of light-matter interactions in the multi-photon regime, as well as for the engineering and modelling of new and robust photon-based quantum technologies.;170121,6;170121,6;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS;ES;;;;1;0;0;1;0;0 215356;795444;ADAPT;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;An adaptation-based approach to understand resilience after job loss:Identifying the underlying mechanisms leading to adaptive coping and re-employment;2019-09-01;2021-08-31;;"Unemployment represents a major societal problem in Europe, strongly related to increasing depression and anxiety rates and high economic costs. In line with European policies on mental health, enhancing resilience against the adverse effects of job loss is a timely priority. In ADAPT, I propose a novel framework and advanced methods to identify the psychological mechanisms (adaptation-based attention and emotion regulation processes) promoting adaptive coping after job loss and facilitating higher possibilities for re-employment. ADAPT is highly original and timely for current societal needs, providing: a) a novel framework beyond traditional approaches in the study of resilience, largely failing to provide successful mental health promotion deliverables; b) fine-grained analyses of adaptation-based mechanisms that can be easily targeted in future assistance protocols; c) integrative analyses of both positive and negative resilience outcomes typically studied in isolation; and d) analyses of dynamics at both short- (immediate daily functioning following layoff) and long-time scales (multi-wave follow-ups across the months following job loss), providing a whole view on the stress-resilience trajectories following unemployment that is lacking in former research. The proposal includes a well-defined program of two-way transfer of knowledge including high-quality training in new advanced techniques for the candidate. ADAPT represents an actual attempt to reach relevant stakeholders in the social assistance and mental health sectors to develop innovative programs of mental health’s promotion. The action will generate knowledge that can be ultimately used to develop interdisciplinary deliverables, including advanced e-tools for early detection of sources of conflict following job loss and guidelines for outplacement services on effective strategies and training protocols to promote adaptive functioning in unemployed seeking assistance.";158121,6;158121,6;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;UNIVERSIDAD COMPLUTENSE DE MADRID;ES;;;;1;0;0;1;0;0 215209;793875;ADMEHE;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Mental health advocacy: Reassessing the history of mental health organizations in the second half of the twentieth century;2019-08-01;2021-07-31;;The research examines the history of advocacy and self-advocacy for mental disorders, mental retardation and autism after WWII, when mental health advocacy gained momentum in the Western world. It focuses on the unexplored Greek case, but situates it within the broader history of social and mental health movements in Europe and North America, based on secondary literature and original comparative research on Greek and French patients’, families’ and professionals’ organizations. Using archival and published material, oral history interviews, questionnaires, as well as data from the observation of and participation in the work of a Greek organization, the Society of Social Psychiatry and Mental Health (SSP&MH), the research adopts an interdisciplinary and comparative approach, combining history with sociology and anthropology, and comparing the Greek and French examples. In these ways the study will offer a better understanding and the critical reassessment of the history of mental health advocacy in the West. To implement the project, Dr Kritsotaki will move from Greece to CERMES3, Paris, France, to sharpen her knowledge and skills in history and undertake systematic training in sociology and anthropology, especially in the skills connected with questionnaire-based surveys, fieldwork and participant observation. She will also collaborate with present-day Greek and French mental health organizations and will complete a secondment of two months in the SSP&MH, gaining hands-on experience on mental health advocacy and enhancing her communication, cooperation, coordination and management skills. Thus the research will address the both the history and contemporary state of advocacy and mental health movements, will achieve its dissemination and communication aims and will enhance its social impact, while at the end of the action the researcher will have attained a reinforced and mature research position and new career prospects in academia and advocacy.;185076;185076;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE;FR;;;;1;0;0;1;0;0 214993;790197;REvolTURN;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Managing Migrant Return through 'Voluntariness';2018-10-01;2020-09-30;;"The fundamental weakness of nation state and EU efforts to effectively manage migration to Europe lies in ensuring the return of foreigners who pass or avoid border controls but are then neither granted asylum nor a residence permit. Many Member States thereby increasingly rely on public policies for the so-called ‘voluntary return’ of irregular migrants and (refused) asylum seekers. Very little is known about how these approaches work in practice and whether they meet stated policy goals and discharge state obligations regarding migrants’ human rights. The project REvolTURN addresses this research gap through a close and comparative analysis of ‘voluntary return’ policies in Austria and the UK, including their adoption, implementation and immediate outcome. It examines 1) how voluntariness of return is constructed and framed in law, policy and public discourse, 2) which notions of voluntariness are crucial for policy implementation, and 3) what impact this has on migrants’ own decision-making about their return. My innovative and interdisciplinary mixed-method approach combines comparative policy and discourse analysis, detailed institutional ethnography through observation and in-depth interviews and a survey among potential returnees. REvolTURN addresses a key priority of the Horizon 2020 work programme for 2016-17: to better manage migration, and will also contribute to recent scholarship regarding the in/effectiveness of migration policies and the agency of migrants holding no or highly precarious statuses. The project has three main objectives: 1) to better understand the role and functioning of voluntariness in the context of state-managed migratory return; 2) to develop a framework for assessing and comparing these roles and functions, including their effectiveness; and 3) to thereby contribute to evidence-based and workable policy solutions that increase the number of genuinely voluntary returns without undermining the very logic underlying this approach.";166156,8;166156,8;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;UNIVERSITAT WIEN;AT;;;;1;0;0;1;0;0 215211;793893;ODYSSEA;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Population Dynamics in the Southeast European Neolithic: Prehistoric Archaeology and Palaeogenomics;2018-10-01;2020-09-30;;"“Population dynamics in the Southeast European Neolithic” is an interdisciplinary project, focusing on the Neolithic transition, a major turning point in human history, when people domesticated plants and animals, and built the first permanent villages. The work of the Palaeogenetics Group in Mainz shows that the first European farmers probably migrated from Anatolia, one of the first regions to adopt agriculture after food plants and animals were domesticated in Southwest Asia. The question that this project addresses is how, in a practical sense, early farmers interacted with foragers, as well as with other farmers, during the initial phases of agricultural spread in Southeast Europe. For instance, is there any evidence that early farmers and foragers lived side by side? If so, did they admix to any significant extent? What was the population structure of early farming communities? And how did the structure of Neolithic settlements affect farmer-forager and farmer-farmer interactions? Specifically, the project will test archaeologically-informed population models and provide context in terms of where ancient DNA results produced by the Palaeogenetics Group sit archaeologically. This will help to lead the field of palaeogenetics from its continental and large-scale oriented perspective towards finer-scale population genetic inference at regional, site-specific or even household levels. For archaeology, this is an opportunity to reclaim the field of prehistoric migrations and engage with the latest results of aDNA research. In the course of the project, I hope to establish myself as an archaeologist who is able to critically evaluate approaches and techniques used in statistical genomics, in order to help bridge the gap and bring prehistoric archaeology and palaeogenomics closer together.";159460,8;159460,8;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;JOHANNES GUTENBERG-UNIVERSITAT MAINZ;DE;;;;1;0;0;1;0;0 215835;801110;ESQ;SIGNED;H2020-EU.1.3.4.;MSCA-COFUND-2017;H2020;ESQ-FP: Erwin Schrödinger Quantum Science Programme;2018-05-01;2023-04-30;;Based on the Austrian scientific excellence strategy, the Erwin-Schrödinger Center for Quantum Science and Technology (ESQ) has recently been launched as a new nation-wide research initiative. ESQ is coordinated by the Austrian Academy of Sciences (OEAW), under the auspices of the Ministry of Science, Research and Economics, in close collaboration with the Vienna University of Technology (TUWIEN), the University of Vienna (UNIVIE), and the University of Innsbruck (UIBK). At present, 28 research groups cooperate in research and training programmes in quantum science and technology. ESQ will serve as a EU hub for Experienced Researchers and ESQ teams will contribute to the European Quantum Flagship Initiative, as well. ESQ supports in particular postdoctoral careers and innovative projects in quantum research and it will gain additional visibility and momentum through the MSCA COFUND program fostering interdisciplinary inter-sectoral research. ESQ supports incoming international fellows in developing their scientific careers. The ESQ fellowship programme offers mentoring by scientists, who were selected for their scientific excellence and it builds on an excellent infrastructure at all partner organizations. ESQ provides an extensive international scientific network and many options for personnel development and acquiring transferrable skills, also with industrial partners. For that purpose, the fellows will also be offered extended academic and inter-sectoral secondments. The ESQ fellowship programme will publish one international call per year to recruit up to 15 fellows distributed over three selection rounds and 54 months. The selection process follows the principles of excellence and transparency and will be supported by a high-level, international selection committee. The ESQ fellowship programme thus enhances the research capacity in Europe substantially as it provides excellent research opportunities to the best young talents in quantum research.;2124000;1062000;H2020-MSCA-COFUND-2017;/MSCA-COFUND-FP;OESTERREICHISCHE AKADEMIE DER WISSENSCHAFTEN;AT;;;;1;0;0;1;0;0 215151;793347;ANTICORPOL;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;New dimensions and approaches to anti-corruption policy;2018-09-01;2020-08-31;;Corruption continues to be a central issue in the governance of institutions (public, private or mixed). The scholars and practitioners working on the topic are facing with two challenges: (1) measurement of corruption, which is a thorny issue on empirical studies of corruption, and (2) the increasing awareness of the failure of most anti-corruption policies. The overarching objective of ANTICORPOL is to introduce a new dimension in the discussion of corruption: the degree of corruption (i.e., the depth as opposed to the spread). The benchmark of ANTICORPOL is this: it is unclear whether a system (organization, public administration) with few individuals who terribly deviate from their duty is less/more corrupt, than one with many corrupt individuals who only slightly deviate from their duty. Therefore, the degree of corruption of its members must be an integral part of the debate about corruption in a system and the development of effective policies against it. This proposal raises the following research questions: (R1) How can the degree of corruption of an individual be defined? (R2) Which policies are effective in reducing the distortion of duties of corrupt individuals? (R3) How can the degree of corruption be incorporated into measurements of corruption, at organization/country level? The proposed research is based on both theoretical and empirical methods and the combination of qualitative, comparative and quantitative analysis. This project is inherently of interdisciplinary interest because corruption is a multifaceted issue with economic, political and sociological dimensions. The research findings will contribute to a deeper understanding of corruption and further to the evaluation of the quality of democracy.;173076;173076;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;FONDATION NATIONALE DES SCIENCES POLITIQUES;FR;;;;1;0;0;1;0;0 215345;795315;FOREPAST;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Past, present and future environmental, biological and social transitions in coastal ecosystems;2019-03-01;2021-02-28;;"Regime shifts are common phenomena in ecological systems. These abrupt changes can be induced by sometimes only slight fluctuations or small perturbations. Current understanding of the mechanisms that produce critical transitions in real-world systems is insufficient. Despite transitions have an anthropogenic origin in most cases, the occurrence of such shifts can have pervasive societal implications, typically due to the impairment of a functionally complex ecosystem state, which delivered a number of ecosystem services, into another degraded state, which tends to provide much less services. Thus, our lack of understanding of so-called early warning signals (EWS) of impending change, can severely impact our capacity to adopt management actions in a timely manner. The main limitation when searching for EWS in ecological data is the short-term duration of most studies. FOREPAST takes an interdisciplinary approach to address this issue, and aims at 1) using the paleoecological record to find EWS, which, 2) then will be validated in contemporary ecosystems by means of a manipulative experiment along a gradient of stress. Given that human development is behind most ecosystem transitions, FOREPAST aims at 3) conveying the results of the natural sciences’ WPs with stakeholders in the area of study, to understand their perceived loss/gain when ecological transitions occur, and the trade-offs the society is willing to make to prevent (or not) these scenarios. The focal ecosystems of this action are the Mediterranean wetlands of the Ebre Delta, which are included in the Natura 2000 Network, for being Habitats of community interest and sites of international importance for Birds. Thus, the results arising from this project will provide relevant information for the application of EU directives, specially related to climate change adaptation and coastal resilience, as well as a great leap for the applicant’s career, with valuable training and high-level publications expected.";170121,6;170121,6;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;UNIVERSITAT DE BARCELONA;ES;;;;1;0;0;1;0;0 215202;793824;NoLiMit;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Non-Linear Bayesian partition-modeling of the Earth's mantle transition zone;2018-09-01;2021-08-31;;"The Earth’s mantle transition zone (TZ) is a complex region exhibiting mineralogical phase changes as revealed by sharp increases of seismic wave-speed near 410 and 660 km depth. The TZ is a key region for understanding how efficient is mantle convection to recycle chemical heterogeneities. Attempts to isolate the effects of temperature and composition on elastic properties have faced several issues. First, due to the imperfect seismic data coverage, the scales of thermal and chemical heterogeneities remain poorly constrained. Second, seismic and mineral-physics data suffer from large uncertainties, and the relation between seismic observables and in situ thermo-chemical parameters remains questionable. To overcome these limitations, this project will use a partitioning (multi-scale) approach to isolate the effects of mantle temperature and composition from comprehensive seismic databases. Using a Bayesian probabilistic framework, the experienced researcher (ER) will simulate the multi-scale physical properties of the TZ, confront the results with high-pressure mineral physics experiments and with predictions from mantle convective mixing models. The interdisciplinary approach of this project relies on using state-of-the-art numerical methods and high performance computing to answer fundamental questions in Earth Sciences. The uniqueness of the approach arises from quantifying in a probabilistic sense how conceptual mantle-mixing models fit seismic data. The skills developed during this project will re-enforce the competitiveness of both institutions to build seismic models, and to study the Earth’s deep interior. The expected researcher outcome is the re-enforcement of his research network; the benefit of a new environment to efficiently prepare articles and professorship applications; and through appropriate training, the capability of developing a research group. Continued international collaboration will be of enduring value for research and student formation.";270918;270918;H2020-MSCA-IF-2017;/MSCA-IF-GF;UNIVERSITE LYON 1 CLAUDE BERNARD;FR;;;;1;0;0;1;0;0 215075;792489;RIGHTS UP;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;THE RIGHT TO THE CITY AND THE AMBIVALENCE OF TOURISM: A COMPARATIVE APPROACH TO MEDIA DISCOURSES AND SOCIAL MOVEMENTS' DISSENT IN VENICE, AMSTERDAM AND BARCELONA;2018-06-01;2020-05-31;;RIGHTS UP approaches the media discourses of the current social movements fighting mass tourism in three European cases: Venice, Amsterdam and Barcelona. Tourism has become a key industry for securing economic growth and full employment, but it has also caused negative externalities to local populations. RIGHTS UP aims at understanding how social movements frame their discourses within their Nation-state, while engaging with solidarity movements or ‘dissent networks’ at the European/global level. The innovative approach combines qualitative in-depth discourse analysis and interviews with a computer-assisted content analysis to secure a diversity of sources, and fosters interdisciplinary/intersectoral collaboration with academics in areas such as geography, economics, urban studies, and political science. The outcomes of the project will impact both local policies (governance) as well as entrepreneurial initiatives in the tourism industry (providing entrepreneurs with information about the needs of local populations and fostering a climate of social responsibility). I have extensive experience researching discourses and narratives in media, and RIGHTS UP expands my career both because of its link to tourism studies as well as because of the emphasis on comparative (European) studies. My proposal is based in the long academic discussion on the right to the city, but complements this approach with the concept of the right to the urban protest. The project is committed with European goals of sustainable tourism and bottom-up governance, and it also observes the emergence of a trans-national public sphere. Ca’ Foscari as host institution and the Universitat Rovira i Virgili (secondment) are both institutions with HR Excellence in Research. The expected results of my project are a better understanding of the effects of tourism in European cities, as well as advancing the scientific knowledge on social movements, urban spaces and contentious politics.;168277,2;168277,2;H2020-MSCA-IF-2017;/MSCA-IF-EF-CAR;UNIVERSITA CA' FOSCARI VENEZIA;IT;;;;1;0;0;1;0;0 215561;797747;ParAdapt;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Theoretical and empirical approaches to understanding Parallel Adaptation;2018-09-01;2020-08-31;;"Adaptation is a key evolutionary process, allowing organisms to thrive in different environments. Studying adaptation is important for understanding biodiversity, and for addressing pressing issues in conservation and medicine. A crucial question is whether adaptive evolution is repeatable and therefore predictable. Patterns in nature suggest that this may be the case: within many species, similar adaptive phenotypes have evolved repeatedly in multiple geographical locations (“parallel evolution”). However, it is often unclear whether the genomic basis underlying parallel phenotypes is the same across locations (e.g. due to mutations in the same gene, or gene flow between locations). With high-throughput DNA sequencing technologies, it is now possible to address this question in unprecedented detail. However, we are lacking a theoretical framework predicting the genomic basis of parallel evolution, as well as powerful analyses of empirical data. Therefore, here I propose an interdisciplinary approach with the following aims: 1. Using computer simulations to study the effects of demographic history and polygeny on the genomic basis of parallel evolution. This will, for the first time, enable quantitative predictions. 2. Generalising the model outlined in 1. by describing it mathematically. 3. Exploring the genomic basis of parallel evolution in an ideally suited organism. I will identify the most powerful analytical methods, and apply these to generate one of the most comprehensive empirical studies so far. This project will be of use to other researchers conceptually, for making system-specific predictions, and by providing widely applicable workflows. It will facilitate new collaborations between my host group (focusing on mathematical analyses of evolutionary processes) and empirical scientists. In addition, it will complement my existing skills in empirical genomics with a new set of analytical and mathematical skills, opening up the best career possibilities.";166156,8;166156,8;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;Institute of Science and Technology Austria;AT;;;;1;0;0;1;0;0 215243;794298;MS-fMRI-QSM;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Studying Multiple Sclerosis with a novel simultaneous functional Magnetic Resonance Imaging (fMRI) and Quantitative Susceptibility Mapping (QSM) sequence.;2019-08-01;2022-07-31;;"Multiple sclerosis (MS) is the most common autoimmune disorder to affect the central nervous system. Demyelination of nerve cells leads to a slowing of electrical signals, causing visual and sensorimotor deficits, cognitive decline and mood changes. Magnetic Resonance Imaging (MRI) plays a central role to in diagnosis through the identification of plaques and active lesions. Recently, functional MRI (fMRI) and Quantitative Susceptibility Mapping (QSM) have been shown to provide insights into the pathogenesis of MS and possible biomarkers of MS subtypes (relapsing-remitting (RR), primary progressive (PP) and secondary progressive (SP)). fMRI shows aberrant neuronal activation in response to motor tasks and changes to the motor resting state networks which are different in RR, PP and SP MS, for instance, whereas QSM provides images of the magnetic susceptibilities of different tissues, revealing iron deposits and demyelination. This action proposes the development of a new MRI sequence which will allow fMRI and QSM data to be acquired simultaneously rather than in two separate scans. This will drastically reduce the scan time, which is vital as many MS patients find it hard to stay still during an MRI. The combined fMRI-QSM sequence used to examine, in different MS subtypes and genders, reorganization of motor function and disruption of functional connectivity (from fMRI) in relation to the distribution of plaques, iron and demyelination (from QSM). The sequence programming in this interdisciplinary project will be carried out under the supervision of Prof. Barth, a physicist who developed the MR method on which the fMRI-QSM scan will be based, at the University of Queensland. In the return phase Prof. Enzinger, one of Europe’s leading MS neurologists, will supervise the clinical study with the combined sequence. This action stands to lead to a step-change in the international standing of the researcher and benefit the host and the European research area.";267458,4;267458,4;H2020-MSCA-IF-2017;/MSCA-IF-GF;MEDIZINISCHE UNIVERSITAT GRAZ;AT;;;;1;0;0;1;0;0 215657;798576;nanoTOM;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Conversion of natural plant nanovesicles into nutraceutical delivery system;2018-10-01;2020-09-30;;"Novel encapsulation approaches to create alternative delivery options for nutraceuticals are emerging as a promising strategy to enhance the bioavailability of poorly absorbed active food ingredients. In this context, nanoTOM aims to exploit edible plant derived nanovesicles and use them as vehicles for the encapsulation, protection, release and bioavailability enhancement of selected nutraceuticals. Plant cells secret phospholipid membrane-surrounded vesicles morphologically similar to mammalian extracellular vesicles. Exploitation of plant nanovesicles is promising although hampered by i) their difficult isolation and ii) the lack of knowledge of their biogenesis, molecular architecture, uptake and biological effects. The experienced researcher is a chemist with strong academic and pharmaceutical background in the isolation and analysis of bioactive compounds from medicinal plants who team-up with the Institute of Biosciences and BioResources (IBBR) with considerable expertise in extracellular vesicle research to realize a uniquely interdisciplinary research program. The research proposed here will realize the following concrete objectives: 1. Set-up an integrated analytical pipeline for the isolation, characterization, encapsulation, uptake and toxicological profiling of plant nanovesicles. 2. Use the pipeline to exploit different Solanum lycopersicum (tomato) nanovesicle populations regarding secretion mechanism, heterogeneity, biocargo composition, nutraceutical and encapsulation properties. Neither of these objectives have been addressed before and both have high potential to expand the knowledge in the field and to drive the research activity towards industrialization. The research objectives are integrated with concerted training objectives in plant, cellular and molecular biology and omics, outreach program, dissemination events and considerable knowledge transfer in the isolation and use of herbal nutraceuticals from the researcher to the IBBR host group.";168277,2;168277,2;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;CONSIGLIO NAZIONALE DELLE RICERCHE;IT;;;;1;0;0;1;0;0 214500;798954;DEFPOLL;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Origins of trait diversity in flowering plants: understanding interactions between plant defence and pollination using molecular, phenotypic and ecological studies of natural selection;2018-06-01;2020-05-31;;"The extraordinary diversity of flowering plants is arguably most evident in two seemingly unrelated aspects of life history: reproduction, exemplified by the stunning diversity in flower form and function; and defence, exemplified by the remarkable variation in toxic chemistry found in the leaves of most plant species. Despite over 150 years of research on these topics, comparatively few studies have addressed how defence and reproduction interact on ecological and evolutionary time scales. This is surprising, first, because variation in sexual reproduction determines key aspects of plant populations that are known to influence the frequency and impact of antagonists such as herbivores and pathogens; and second, because herbivory and disease are ubiquitous stresses that influence plant reproductive success. Feedbacks between defence and sexual reproduction therefore represent a rich set of unexplored mechanisms explaining important components of plant trait diversity. The objective of this proposal is to address this knowledge gap by answering two questions: First, what are the immediate consequences of a shift in a plant species’ reproductive strategy for interactions with pollinators and herbivores? Second, what are the impacts of these altered species interactions for plant fitness and the evolution of both leaf defence traits and floral pollination traits? To answer these questions, I will gain training in plant molecular biology, allowing me to combine cutting edge genome-editing techniques and gene expression analyses with my own expertise in evolutionary ecology and chemical ecology. With this interdisciplinary approach, I will assess novel genetic and ecological factors underlying variation in defence and pollination phenotypes, two classes of plant traits that are of critical significance in both wild and managed plant species.";183454,8;183454,8;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;THE UNIVERSITY OF SHEFFIELD;UK;;;;1;0;0;1;0;0 215573;797881;SOLMUS;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Social Landscapes as Multicultural Spaces: Steæci in Bosnia and Herzegovina;2018-09-01;2020-08-31;;Steæci, the medieval tombstones, are expressions of religious belief, identity, politics and social ideology. They synthesise the historical, chronological, cultural and religious components of the medieval Western Balkans. There are over 60 000 steæci scattered around Bosnia and Herzegovina (BiH), the country that epitomises long-standing plurality. Through these monuments identities were enunciated, thus offering a rare opportunity to investigate the archaeo-historic growth of medieval SE Europe. SOLMUS adopts an innovative and interdisciplinary approach to study medieval funerary archaeology, with the aim to understand the social life of medieval Bosnian society that left us steæci. SOLMUS will model ‘inter/intra group’ interactions in medieval BiH by integrating principles from landscape archaeology, remote sensing, digital humanities, and the scientific and theoretical approaches of social archaeology with medieval iconography and epigraphy, therefore bringing an entirely new understanding of European medieval archaeology. The proposed project will synthesise complementary datasets from the archaeological and historical record, often treated separately. By defining the Past as shared, complex and nuanced, can archaeology stimulate new narratives for social integration? What was/is the regional impact of the peripheral East and the role of multiculturalism on the European Past? Dr Èaval is an experienced researcher, focusing on the archaeology of religion, historical archaeology and cultural astronomy. She will enhance her research and employability through training in theoretical, methodological and practical knowledge in social archaeology, as well as skills in SNA, RTI and GIS analyses (beneficiary), and medieval epigraphy and iconography (secondment). By bridging theoretical perspectives and scientific methods, she will provide innovative perspectives on European multiculturalism through its relationship with the medieval heritage of the Western Balkans.;195454,8;195454,8;H2020-MSCA-IF-2017;/MSCA-IF-EF-RI;THE UNIVERSITY OF READING;UK;;;;1;0;0;1;0;0 215113;792994;PiCoBoo;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;19th-Century European Picture-Books in Colour;2018-09-24;2020-09-23;;"The PiCoBoo project aims to assess the significance of 19th-century European picture-books, printed in colour for children, as a catalyst for major cultural and social changes. From the 1830s, new techniques were developed that allowed to print colour in a cheaper, greater and more refined extent: for the first time, people – no matter their age, gender, social class, ethnicity, nationality – saw the world in colour. It is remarkable that this major revolution in visual culture had its birth in books for children. It is doubly remarkable that neither children’s book scholars nor book historians have investigated the genesis, development and effects of this major shift in print culture. We lack studies of how colour became prevalent in children’s books, expanded more widely through print and spread across national boundaries. PiCoBoo will draw new attention to this important chapter in the history of the book through publications, exhibitions and conferences. Adopting an object-based interdisciplinary approach, this will be the first detailed account of 19th-century colour picture-books for children: what they were, when, where and how they were made, who produced them and for whom, what their role in cultural, publishing and visual history and their long-term influence. In the absence of European aggregators of children’s books, PiCoBoo will build a network of collections of colour picture-books and, in the unreliability of collection and library catalogues, it will establish protocols for recognising and cataloguing them. PiCoBoo will be hosted by the Children’s Literature Unit at Newcastle University, UK, with a Secondment at the Victoria & Albert Museum, London, and in partnership with Seven Stories, the UK’s National Centre for Children’s Books. It is especially timely because only recently the Alderson Collection, the most significant gathering of British children’s books still in private hands, has been donated to Newcastle and made accessible to the public.";195454,8;195454,8;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;UNIVERSITY OF NEWCASTLE UPON TYNE;UK;;;;1;0;0;1;0;0 214968;789670;SELECT;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;SEmiconductor disk Lasers for EffiCient Terahertz generation;2019-01-01;2020-12-31;;"The primary goal of this Fellowship, entitled “SEmiconductor disk Lasers for EffiCient Terahertz generation” (SELECT), is to train a talented researcher through a research project focused on the development of high-performance laser sources based on semiconductor disk lasers and novel periodically poled ferroelectric and semiconductor crystals that can offer an access to new wavelengths not covered by available gain media, particularly in the THz spectral region, which are desired for THz spectroscopy, Biomedical imaging, and Safety and Security applications. The novel high-performance vertical-external-cavity surface-emitting-laser, with remarkable output parameters, will be used as a source of ultra-efficient THz emission in the 0.8-3THz spectral window based on difference frequency generation in advanced quasi-phase-matched crystals. The success of the interdisciplinary project will lead to a number of multidisciplinary disruptive innovations in Photonics with significant scientific, technical, economic and social impact, from spectroscopy and biomedical imaging to security screening and quality control. The Fellow - Dr. Ksenia Fedorova - will be trained in the fast growing field of science, technology and industrial applications of semiconductor lasers and THz technology, receiving access to a unique training experience at the host – Philipps- Universität Marburg, and at academic and industrial secondments: Aston University, Innolume GmbH, M-Squared Lasers Ltd. The project will enable the Fellow to be a rare asset to European research; she will gain a set of multidisciplinary professional skills in both theoretical and practical fields, starting from the laser system design and fabrication and finishing with implementing the final product into real industrial applications. The SELECT outputs will be relevant to the EU Photonics industry through offering new efficient compact THz lasers, which will also contribute to the enhancement of EU scientific excellence.";159460,8;159460,8;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;PHILIPPS UNIVERSITAET MARBURG;DE;;;;1;0;0;1;0;0 215328;795209;PREMEDiCARE;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;PREcision MEDicine with induced pluripotent stem cells for Cardiac Arrhythmias Risk Evaluation;2018-10-01;2020-09-30;;"Long QT Syndrome (LQTS) is a severe arrhythmogenic condition characterised by the prolongation of the QT interval on the electrocardiogram. It is caused by genetic factors (congenital) or drugs (acquired) and sudden cardiac death can be the first manifestations of the disease. Advancements in genetic screenings have revealed profound links between genotype and phenotype for LQTS, improving diagnosis, risk stratification and therapy; However, it is still poorly understood why patients with identical pathogenic mutations have different clinical phenotypes, which factors are involved in this unpredictable disease severity and how we can protect these subjects from drug treatments that are safe in the general population. We do need improved and more physiological in vitro models to simulate arrhythmias in vitro, effective for drug testing, to identify, evaluate and study factors that shape the arrhythmogenic risk in vulnerable subjects. Here I propose a precision medicine approach that uses human pluripotent stem cells-derived cardiomyocytes (hPSC-CMs) from LQTS families (rare resources that include male, female, symptomatic and asymptomatic patients) to: i) demonstrate that the hiPSC technology can reproduce in vitro the clinical disease severity observed in symptomatic vs asymptomatic LQTS mutation carriers; ii) create an in vitro interdisciplinary pharmacological approach with proarrhythmic drugs which combines matched electrophysiological, contractile, molecular and genetic assays; iii) identify and evaluate the factors affecting the arrhythmogenic risk in predisposed subjects. This pipeline to assess arrhythmia susceptibility from patient-specific hiPSC-CMs can be applicable to other arrhythmogenic syndromes. The results of this project will contribute to reduce the use of animal models in preclinical research, to create safer, more effective drugs for humans and to promote the shift of new therapeutic approaches towards precision or personalised medicine.";168277,2;168277,2;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;ISTITUTO AUXOLOGICO ITALIANO;IT;;;;1;0;0;1;0;0 215043;792150;LadinoProverbs;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Ladino Proverbs: Edition, Recovery and Dissemination of the Endangered Cultural Heritage in the post-Holocaust Yugoslavia;2019-09-01;2021-08-31;;"This research project will constitute the first peremiological study of the Sephardic tradition from Serbia and Bosnia. Whereas other forms of the Ladino oral tradition from these countries such as ballads, songs or folktales have all been analysed, the proverb tradition remains largely unstudied. Thus my project seeks to fill a serious void in this field. I intend to edit and examine five manuscripts containing proverbs from these countries. All five manuscripts are postHolocaust. Three are exclusively in Ladino, whereas two are bilingual (Ladino/Serbian). The study will entail an analysis of the literary genre of the proverb from an interdisciplinary approach that will include contributions from biblical studies, medieval Iberian cultural studies, modern Balkan history, sociological criticism, linguistics, and folklore paremiology and narrative. The study will also include a cross-cultural analysis of the proverbs using a comparative method. The ultimate goal of this project is a monograph intended to preserve, revitalise and disseminate the endangered Ladino language and culture. Prof. Paloma Díaz-Mas, who works in the Instituto de Lengua, Literatura and Antroplogía (ILLA) of the Centre for Human and Social Sciencies (CSIC, Spain) is the ideal person to supervise my work. She leads a research group that focuses on the culture of post-diaspora of Hispanic Jews (Sephardim) and has an extensive and prominent list of works on the topic published either independetly or in collaboration with other members of the project. By joining her group I would be given the opportunity to [the] acquire new skills (transliteration of Ladino texts written in Hebrew script[s]; edition of texts) and disseminate my work among both academic and non-academic audience through a number of activities (international conferences, workshops and seminars; radio and television programmes; participation in Science weeks and fairs,organisation of exhibitions and promotional talks).";158121,6;158121,6;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS;ES;;;;1;0;0;1;0;0 215740;799510;OSTtrans;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;The Role of OST?/? as a Bile Acid and Drug Transporter in Obesity-Associated Chronic Liver Disease, Nonalcoholic Fatty Liver Disease;2018-09-01;2020-08-31;;"Obesity is increasing rapidly in EU, with about 50% of the population being obese. In addition to cardiovascular disease and type-2 diabetes, non-alcoholic fatty liver disease fatty liver disease (NAFLD) is a major obesity-associated chronic disease. Despite the high frequency of NAFLD, comprehensive research on its effects on hepatic biotransformation capacity is lacking, especially in human subjects. This project will use human liver tissues, human hepatocytes, organic solute transporter ?/? (OST?/?) over-expressing human cells and membrane vesicles, to evaluate the role of OST?/? and other bile acid transporters in NAFLD, addressing a key question in current biomedical research: Can obesity lead to altered hepatic biotransformation and modulate the efficacy and safety of medications? The main objective is to elucidate the role of OST?/? as a bile acid and drug transporter particularly in NAFLD. The hepatic expression of OST?/? is normally low but dramatically increased in cholestatic conditions, even more than expression of other bile acid transporters. The project will focus on the proteomics of bile acid transporters and bile acid metabolome in NAFLD and NASH liver, regulation and mechanisms of OST?/? transport, and the role of OST?/? as a bile acid and drug transporter in the human liver. The project is strongly interdisciplinary, involving a combination of biochemistry, molecular biology, and analytical chemistry. The results will increase the understanding of NAFLD disease mechanisms, thus benefitting clinicians and authorities to ensure safe and effective drug therapies for the NAFLD population. This project examines one of the key priorities of European Commission, chronic diseases. In addition, the Applicant enhances her competences and the host widens its networks, thus supporting mutual knowledge transfer.";179325,6;179325,6;H2020-MSCA-IF-2017;/MSCA-IF-EF-RI;ITA-SUOMEN YLIOPISTO;FI;;;;1;0;0;1;0;0 215315;795070;PHOTO-CY-APPs;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Photosynthesis and photoprotection regulation in marine cyanobacteria and its potential applications;2018-06-01;2021-05-31;;Carotenoids evolved in cyanobacteria as components of membranes providing a structural role and likely influencing permeability to oxygen. Then they became complexed with proteins that enabled a great diversification in their functions to include both 1O2 quenching and light harvesting in photoprotection. Photo-cy-apps is an ambitious project with the purpose of gaining a comprehensive understanding of the role of OCP and the new HCPs and CTDHs on photoprotection in marine cyanobacteria, with their potential application. The ecological importance of these microorganisms reinforces the relevance of this project, since the putative protecting role of OCP in a major subset of marine picocyanobacteria could be a key factor for their abundance, particularly in regions close to the surface of the ocean, subjected to high irradiances. This project brings two research laboratories together with different and complementary expertise, the Kerfeld lab at the Plant Research Laboratory (PRL) at Michigan State University (MSU and LBNL) in the USA with the expertise in bioinformatics, biophysics and structural biology, and the Garcia-Fernandez lab at the University of Cordoba (UCO) in Spain with the expertise in physiological studies in marine cyanobacteria, to determine the role of these car-binding proteins in marine photoprotection and provide the foundation for the Fellow for her independent career after this interdisciplinary training-through research.;239191,2;239191,2;H2020-MSCA-IF-2017;/MSCA-IF-GF;UNIVERSIDAD DE CORDOBA;ES;;;;1;0;0;1;0;0 215123;793082;MMSA;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Molecular Motors for Surface Applications;2018-04-01;2020-03-31;;Over the last few decades the field of artificial molecular motors/switches has evolved into a cornerstone of chemical research. Molecular motors are now widely expected to play a leading role in the nanotechnological revolution of the 21st century as they are central to the transition from static to responsive/adaptive materials and molecular devices. Feringa's unidirectional rotary motors are unique in their potential to perform continuous work and are recognized as having a multitude of possible applications. However, necessary use of UV light as well as poorly understood behavior of surface bound rotary motors has so far hampered their development. The research outlined in this proposal is aimed at overcoming these limitations by exploring two-photon absorption pathways as well as upconverting nanoparticles to drive molecular rotation with near-infrared light. Secondly, scanning tunneling microscopy will be used to gain insight into the rotational behavior of surface bound rotary motors on the basis of individual molecules as well as their organisation into self-assembled monolayers. This knowledge will subsequently be applied to showcase three distinct, exemplary applications: Firstly, individually addressing the states making up the rotational cycle of motors incorporated into self-assembled monolayers will be studied for its potential use in molecular information storage. Secondly, the coordinated rotation of surface bound motors will be harnessed in order to achieve transport of microscale objects. Lastly, the influence of the dynamic behavior of a motor functionalized surface on stem cell adhesion will be explored. MMSA is therefore an interdisciplinary project at the interface of chemistry, surface science, nanorobotics and cell biology, placing it at the forefront of science.;165598,8;165598,8;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;RIJKSUNIVERSITEIT GRONINGEN;NL;;;;1;0;0;1;0;0 215398;795921;urbanbird;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Social life in the city: how urbanization affects cooperation and competition among social birds;2018-04-01;2020-03-31;;Urbanisation currently forms one of the most important threats to biodiversity. Urbanization involves a drastic change of the environment, which will require species to adapt. Studies have shown that animals in urban environments differ in their behaviour, morphology and physiology from those in rural environments. However, how these differences come about remains unclear. Individuals might be able to show plasticity in their behavioural response to the new environment. Alternatively, certain types of individuals might be more likely to move to cities, or certain individuals might be more successful there. Despite the attention on how urbanization has affected behavioural changes to the environment, the effect on intra-specific social behaviours has been neglected, despite its importance for fitness. Furthermore, the long-term consequences of urbanization for populations remain unknown. The proposed project aims to investigate the underlying mechanisms of changes in social behaviours and the long-term population consequences. I will use the house sparrow (Passer domesticus) as a model system, which although widespread in both urban and rural environments, has undergone extreme declines, particularly in European cities. Using a citizen science approach, combined with new experiments, the knowledge generated by this project will help predict the effects ongoing urbanization will have on species and biodiversity. During this interdisciplinary project I will exchange knowledge with experts in the field of conservation and applied ecology. The proposed fellowship will allow me to re-enter the European academic system and develop skills required to initiate my own effective research group following the project.;177598,8;177598,8;H2020-MSCA-IF-2017;/MSCA-IF-EF-RI;STICHTING KATHOLIEKE UNIVERSITEIT;NL;;;;1;0;0;1;0;0 215177;793612;TREGinAD;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Role of A? Specific Regulatory T cells in harnessing cerebral A? clearance in Alzheimer’s Disease;2018-04-01;2020-03-31;;"With populations ageing, Alzheimer’s disease (AD), for which there is still no cure, has become a major public health problem in Europe. This is partly due to the neglect of the role of the immune responses to the build-up of cerebral A?-the pathogenic agent triggering AD. Clinical trials for vaccines aimed at reducing cerebral A? were accompanied by severe side effects due to improper neuroinflammation. While the input of microglia, the brain resident innate immune sentinels, is becoming clearer, the impact of the adaptive immune system, specifically T cells is still unknown. A promising therapeutic strategy, would be to strengthen A?-induced regulatory T cells (Treg), to alter the effector T cell mediated inflammatory response, while promoting clearance of A? by microglia. My interdisciplinary project hosted by Trinity College Dublin and supervised by Prof Lynch will draw together both Neuroscience and Immunology. I propose to assess the effect of A?-specific Treg on the pathoethiology of AD. To this aim, I will amplify a population of A?-specific Treg in the APP/PS1 mouse model of AD and will 1) assess if A?-specific Treg can regulate instruction of microglia to clear cerebral A?, while keeping inflammation under control, 2) determine if this regulatory effect occurs via paracrine mechanisms from the periphery or if Treg physically enter the CNS and 3) identify other A?-specific T cell populations involved in response to cerebral A? build-up and in alteration of microglial phagocytic activity. Completion of this project will make a critical contribution to the understanding of the immune response in AD and will pave the way towards safer therapeutic tools. The proposed action will allow the dissemination of my work to both neuroscientists, immunologists, and the general public. I will reinforce my multidisciplinary and inter-sectoral skills, improve my management and teaching experience to establish myself among the leaders of research at ERC level.";187866;187866;H2020-MSCA-IF-2017;/MSCA-IF-EF-RI;THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN;IE;;;;1;0;0;1;0;0 215710;799162;ESSINDEX;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Essential Indexicality;2019-09-01;2021-08-31;;My aim in the project ESSINDEX is to understand the phenomenon of essential indexicality. Indexicals are linguistic terms such as ‘I’, ‘here’, ‘now’, ‘he’, etc. whose referent varies according to the context of use. For example, an utterance of ‘now’ refers to the time of its utterance. Like other context-dependence phenomena, indexicality had long been regarded as a defect of natural language. But in 1970, it was noticed that some thoughts cannot be expressed or communicated without the help of indexicals. Such thoughts appear to represent the world from a situated perspective in it. This creates a deep problem for traditional doctrines about thought and communication: the “problem of the essential indexical” (PEI). The PEI has generated a vast literature in the last 40 years. It has foundational implications in philosophy of language, philosophy of mind, semantics, and pragmatics. This is the perfect time for a renewed assessment of the PEI: recent sceptics began to complain that the PEI was ill-posed and that essential indexicality was a myth. The novel view I propose to explore in this project integrates insights from both the advocates and the detractors of essential indexicality. It could mark a turning point in debates on the PEI, and thereby have broad implications for the relevant fields. I want to run ESSINDEX under the supervision of François Recanati at the Institut Jean Nicod (IJN), which is partnered with the École Normale Supérieure (ENS) in Paris. Given the unrivalled expertise of F. Recanati on most topics of ESSINDEX, and that of other researchers at IJN on specific issues to be explored in various research fields (philosophy of language/mind/cognitive science, semantics/pragmatics, epistemology), the interdisciplinary team of IJN provides the best possible environment in which to run that project, which directly engages with the current work of several of its researchers.;173076;173076;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;ECOLE NORMALE SUPERIEURE;FR;;;;1;0;0;1;0;0 215178;793639;PEDAS;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;The Political Economy of Data: Comparing the Asian Giants;2018-10-01;2020-09-30;;"Some are now calling the data trails we leave on the internet the “new oil” as tech firms like Google and Facebook become rich extracting, refining and selling this 21st century resource. But this lucrative business model is now being challenged from two directions: (1) a new EU regulation starting in May 2018 which will return ownership of personal data to the user rather than the website (2) computer scientists are developing software for decoupling personal data from the websites used, enabling individuals to control and sell their own data. As the US tech firms now turn to the populous, young, tech-savvy emerging economies for their data, this research documents the effects of these developments in two countries with fast growing online populations: India and Indonesia. It is only by highlighting the repercussions of these changes for the countries with the largest reserves of this new resource that we can avoid a new wave of unequal exploitation – a digital colonialism. This research lays the foundations for a new theory of the international political economy of personal data. It will do so by charting the unintended consequences of the EU regulation on the negotiations between governments, civil society groups and tech firms in India and Indonesia. Will the European concept of “data portability” be adopted by these governments, enabling Asian internet users to gain a bigger share of the value that data generates? It will use a policy network analysis methodology with media research and interviews; evaluate a prototype personal data software for the Asian context; and seed the development of an international research network. By bringing together a researcher on Indonesian politics with mentors who can guide her on the technicalities of personal data software and Indian policy-making, it will not only provide timely input for European policy-makers, but will also produce a new kind of interdisciplinary researcher for the digital age.";183454,8;183454,8;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;THE UNIVERSITY OF NOTTINGHAM;UK;;;;1;0;0;1;0;0 215138;793226;ADCLICH;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Climate change and evolution: effects on phenotypic plasticity and genetic pattern;2018-06-04;2020-06-03;;With the consensus that human activities are leading to dangerous interference in Earth’s climate, there has been growing policy pressure for clear quantification and attribution of the resulting biological impacts. For this reason, there is an urgent need to understand the effect of ecological and evolutionary processes caused by past climate change on range dynamics. In fact, adaptation of plant populations in fitness-related traits to different local climate condition might enable species to take on future climate change. In general, species performance (genetics, physiology, morphology and demography) is predicted to decline gradually from population growing in the climatic optimum (central population) to population growing in harsh climate conditions (peripheral populations). However, studies aimed to analyse differences between central and peripheral populations relate this differences with only one or two possible causal factors (i.e., historical, ecological or biogeographic factor), without distinguishing between geographical, environmental and historical isolation. For this reason, the goal of our project is to evaluate whether the environmental (ecological niche), historical (biogeographical processes) and geographical barriers may explain difference in both gene diversity and fitness-related floral traits between central and peripheral populations in Lilium pomponium, a species potentially prone to extinction risk because of range loss induced by climate change and spanning across Mediterranean to Alpine climate. The originality and interdisciplinarity of this research programme lies into integrate ecological niche characteristics together with current and past range structure to investigate evolutionary processes that have affected spatial patterns of genetic and demographic variation across species ranges combining different research fields in evolutionary biology as reproductive biology, ecology, phylogeography and population genetics.;185076;185076;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;UNIVERSITE D'AIX MARSEILLE;FR;;;;1;0;0;1;0;0 215246;794354;MUST;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Magnetoelectric Ultra-low-power Spin-wave Transducers;2018-04-01;2020-03-31;;"The ability to control the magnetisation of magnetic materials by electric fields is highly desirable from both scientific and technological viewpoints. Magnetoelectric materials are materials that link electric fields to magnetic properties via mechanical degrees of freedom. Using such materials, we propose to control ultrafast magnetisation dynamics by GHz electric fields and develop novel hybrid electro-magneto-mechanical devices at the nanoscale. More specifically, we propose magnetoelectric devices that act as transducers between electrical and magnetic domains. MUST will use magnetoelectric composites, consisting of piezoelectric and magnetostrictive bilayers, to generate spin waves or excite ferromagnetic resonance using electric signals via mechanical strain. MUST will investigate geometries exerting in-plane or out-of-plane stress to achieve the highest magnetoelectric coupling and enable the most energy efficient spin wave generation and detection. Moreover, MUST intends to study magnetoelectric composites at the magnetoacoustic resonance, with the promise of a strongly enhanced magnetoelectric coupling. The targeted small lateral scale (500 nm) and high operation frequency (bandwidth above 20 GHz) bring such transducers to the frontier of ultrasound devices. Furthermore, MUST will experimentally demonstrate a novel approach for spin wave excitation by the vibration of a magnetic domain wall induced by mechanical actuation in a magnetoelectric transducer. By an interdisciplinary approach combining magnonics and ultrasound devices, as well as nanofabrication, MUST intends to enhance the understanding of the almost unexplored territory of magnetoelectric phenomena at the nanoscale and at GHz frequencies and establish a versatile magnetoelectric transducer platform that can be used in various magnonic (logic) applications.";160800;160800;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;INTERUNIVERSITAIR MICRO-ELECTRONICA CENTRUM;BE;;;;1;0;0;1;0;0 215080;792652;FADAMES;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Fatigue damage at mesoscopic level. Fatigue life prediction in conjunction with acoustic emission signals;2018-07-01;2020-06-30;;Fatigue is the primary damage mechanisms of structural components that usually occurs in three stages: crack initiation, growth of short cracks and growth of long cracks. At macroscopic level, the fatigue damage of materials and respectively failure of structural components, is influenced by the loading mode, geometry, material properties and environment. There are many factors to be taken into account and implicitelly this falls upon the prediction level. Passing to mesoscopic level, the loading mode and geometry effects are included on the stress and strain state and the prediction of fatigue damage depends by the interaction between the stress and strain state and respectively the crystallographic characteristics of material grains. Therefore, it is expected that the prediction level of fatigue damage to be higher and this is confirmed by the studies already initiated. This project proposes an extension of mesoscopic level studies for real loading cases characterized by multiaxial stress and strain states. To analyze the interaction between the multiaxil stress and strain state and crystallographic characteristics of material grain, the project involves both numerical analyzes using submodeling technique and experimental techniques for monitoring the fatigue damage. Acoustic emission technique will be primarily used and simultaneously deeply explored. The purpose of using this technique is to establish clear connections between the mechanisms that generate acoustic signals and the fatigue damage at mesoscopic scale. As the results of this interdisciplinary research consists on the one hand the development of a new concept for fatigue life prediction based on the physical degradation mechanisms of the materials. On the other hand, the investigation results in the development and improvement of the acoustic emission technique, already known as one of the most promising techniques of Structural Health Monitoring.;195454,8;195454,8;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;CARDIFF UNIVERSITY;UK;;;;1;0;0;1;0;0 215071;792572;MachineCat;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Machine Learning for Catalytic Carbon Dioxide Activation;2018-06-01;2020-05-31;;"The goal of MachineCat is to obtain fundamental insights into machine learning methods applied to computational chemistry problems. Machine learning methods can be used to reproduce the predictions of highly accurate electronic structure calculations at only a fraction of the original computational cost. As a consequence, it becomes possible to simulate chemical problems usually beyond the capabilities of standard computational chemistry methods. However, a routine application of machine learning methods in computational chemistry is made difficult by their inherent black box nature. MachineCat will illuminate this black box by using state-of-the-art analysis techniques to gain a deep understanding on how these learning machines operate. Based on these insights, MachineCat will then systematically improve existing machine learning methods for computational chemistry. To this end, an organocatalytic conversion reaction of carbon dioxide will be investigated. This class of reactions is highly relevant for sustainable chemistry, as it offers cheap access to value-added chemicals, potentially replacing fossil fuels as primary carbon source. By studying one particular carbon dioxide conversion reaction with machine learning methods, MachineCat will not only push the limits of these methods, but also provide a detailed mechanism for the reaction under study for the first time. MachineCat will then use this information to rationally design improved catalysts for the conversion reaction. The researcher will gain expertise in modern machine techniques and transfer expertise in computational chemistry to the host. The networks of researcher and host will profit from two interdisciplinary workshops. MachineCat will prepare the researcher for an independent career, providing him with a unique research profile, excellent teaching and presentation skills, strong management capabilities, extensive experience in public engagement and dissemination, and a wide scientific network.";159460,8;159460,8;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;TECHNISCHE UNIVERSITAET BERLIN;DE;;;;1;0;0;1;0;0 215541;797433;LOVE;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Love Across the Divide in Northern Irish Literature and Culture: 1968 - present;2018-10-01;2020-09-30;;"LOVE will enable the experienced researcher, Dr. Alison Garden (AG) to undertake a 24-month fellowship at Queen’s University Belfast QUB) to deliver a project on ‘Love across the Divide’ in Northern Irish literary and cultural texts from 1968 onwards, under the supervision of Professor Fran Brearton (FB). This period of mobility will see AG learn new research-specific skills through working closely with academic experts at QUB; continue her professional development by attending courses offered by the QUB ‘Staff Training and Development Unit’ (STDU); conduct outreach activities with local schools through a partnership with international storytelling organisation, Narrative4 (N4); and gain research-relevant inter-sectoral experience through prestigious secondments at the Seamus Heaney HomePlace (SHH; (from months [M]7-9) and the British Broadcasting Corporation Northern Ireland (BBC NI; M13-16). Combining critical and practice-based methods will generate pioneering research, which will be innovatively disseminated for diverse audiences within and beyond the academy. LOVE will augment and advance AG’s international reputation as a leading scholar of interdisciplinary literary research.";183454,8;183454,8;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;THE QUEEN'S UNIVERSITY OF BELFAST;UK;;;;1;0;0;1;0;0 214613;759707;NUCLEAR;SIGNED;H2020-EU.1.1.;ERC-2017-STG;H2020;Nuclear Weapons ChoicesGoverning vulnerabilities between past and future;2018-09-01;2023-08-31;;"Nuclear weapons choices commit populations and societies for decades and can wipe them out in matters of minutes. How is the scope of available nuclear weapons choices decided? Direct experience cannot be the answer as no one can rely on personal experience of nuclear war. Most decision-makers no longer even have the experience of the effects of such weapons either given that North Korea has been the only country testing nuclear weapons since 1998. The populations’ wishes do not qualify either, since they are very rarely consulted and only few studies on those attitudes exist. Therefore this project offers the first in depth global investigation of the grounds on which the scope of publicly acceptable nuclear weapons choices have been based since the end of nuclear testing. To do so, this project constructs an interdisciplinary research program about responsibility in an age of nuclear vulnerabilities. It investigates four ways in which nuclear weapons choices are bounded: 1) the intellectual categories we depend on to think about those issues; 2) the governance of nuclear knowledge by nuclear-weapons related institutions; 3) specific readings of the past identifying events or trends from which lessons are expected to be learned about the scope of the possible, and 4) the imaginary of possible futures as opposed to the ones deemed utopian. Combining archival research and interviews worldwide, with large-scale polling and discourse analysis of policy officials and strategists over several decades, it assesses the blinding power of categories created several decades ago and sometimes still deemed as irreplaceable lexicon of the nuclear age as well as the way in which nuclear weapons programs modify the governance of knowledge. Based on those findings, it offers a renewed notion of responsibility in the nuclear age built on full awareness of nuclear vulnerabilities in their epistemic and political dimensions, and not only the material ones.";1480145;1480145;ERC-2017-STG;/ERC-STG;FONDATION NATIONALE DES SCIENCES POLITIQUES;FR;;;;1;0;0;1;0;0 215286;794733;Radio-NP;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Computational characterisation of radiosensitising nanoparticles and their properties;2019-07-01;2021-06-30;;Coated metal nanoparticles (NPs) in molecular environments are widely studied for applications in nanobiotechnology and nanomedicine. Understanding of the nanoscale phenomena (formation and transport of secondary electrons, free radicals and their chemical interactions) induced by NP irradiation with ion beams is crucial for enhancing the potential of novel radiotherapy techniques. The Radio-NP project aims at the atomistic computational analysis of (i) structural properties of coated metal NPs in biological environments and (ii) the impact of these properties on the formation and transport of secondary electrons and radicals in the vicinity of NPs irradiated with ions. The realised approach will combine (i) the ab initio framework to evaluate parameters of quantum transformations of system constituent molecules, (ii) classical molecular dynamics (MD) employed in the advanced scientific software MBN Explorer to characterise NPs and study their interaction with molecular media, and (iii) irradiation-driven MD - the novel and unique implementation in MBN Explorer, to model random interactions of the medium with secondary electrons emitted from the NPs, with account for possible chemical transformations. The recently developed IDMD approach will be applied for the first time to model irradiation-induced chemistry in the vicinity of complex NPs. This methodology will go beyond the physics of the Monte Carlo approach widely used to study nanoscale mechanisms of energy deposition under NP irradiation. The interdisciplinary research program of Radio-NP will be carried out at MBN Research Center - an SME that develops MBN Explorer software. Radio-NP will combine applicant’s knowledge in radiation physics and chemistry with strong expertise of the host in professional software development. The applicant will thus gain a broad set of scientific, technical, complementary and entrepreneurial skills that are highly demanded for his further career as a professional researcher.;171460,8;171460,8;H2020-MSCA-IF-2017;/MSCA-IF-EF-SE;MBN RESEARCH CENTER GGMBH;DE;;;;1;0;0;1;0;0 214504;800560;DESIGN;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Design Thinking in Defence Organisations: The Promises and Dangers of Intellectual Emancipation in the Management of Violence;2019-04-01;2021-03-31;;The DESIGN project will conduct sociological study of the relationship between radical ideas, change, and violence in defence organisations based on the ongoing transnational diffusion of second generation design across four NATO member and partner organisations: NATO Defence College, the Royal Danish Defence College, the Design Centre for Excellence (Poland) and Swedish Defence University. Design means the art of transforming reality into a preferred one by opening conceptual possibilities that were unthinkable before. This add-on to defence planning is paradoxical as it seeks to leverage the critical and creative capacities of officers at the expense of the very principles sustaining modern defence organisations. The project will investigate what made this development possible and what differences, if any, design is making to those managing violence and to those being managed by violence? To provide unique answers to these questions, UCPH Centre for Experimental Economics (CEE) will provide training to adapt field experiment methods to sociological approaches to better observe design in practice. Using this new method promises data challenging deeply held assumptions on the relationships between ideas, change and violence in International Relations and Design Studies. A broader impact can also be expected by exposing the promises and dangers of design thinking to both users and stakeholders. I will significantly benefit from undertaking the action at UCPH as it is uniquely equipped to develop the interdisciplinary assemblage required. The project will benefit from being located at the intersection of three leading research centres in the Department of Political Science: the Centre for Military Studies (CMS), the Centre for Advanced Security Theory (CAST) and the Centre for Resolution of International Conflicts (CRIC). Beyond the University, Copenhagen is an ideal location to learn from its avant-garde design movement in private, public and education sectors.;212194,8;212194,8;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;KOBENHAVNS UNIVERSITET;DK;;;;1;0;0;1;0;0 214428;796487;COINE;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Counterfeiting Empire: Money, Crime, and Politics in the British Atlantic World;2018-09-01;2020-08-31;;"COINE will provide the first comprehensive history of counterfeiting as an imperial crime, demonstrating that it had wide-ranging implications for market development, cultures of money and the market, and imperial authority in the eighteenth-century British Atlantic world. Combining methods from social, cultural, and political history with analysis of material and visual culture, COINE engages with interdisciplinary issues, including the dynamics between crime and economic development; the relationship of money to the state; and the evolution of money in the modern world. To accomplish COINE’s objectives, the Experienced Researcher (ER) will complete six months of field work in British archives, collecting data on British-based counterfeiting networks which will be assembled into a relational database and integrated into the ER’s existing database on counterfeiters operating in the British colonies. This data will allow the ER to accurately trace, for the first time, the movements of counterfeiters and their extensive networks in the British Atlantic world. Based at University of Birmingham (UoB) and benefiting from the expertise of the Supervisor and the Birmingham Eighteenth-Century Center, the ER will produce a monograph, Counterfeiting Empire, on money, crime, and politics in the eighteenth century. The results will also be disseminated in a single-authored article and conference presentations. COINE is thus designed to allow the ER to access critical archives, complete data analysis and writing that will be enriched by the intellectual community at UoB, and disseminate results that will change how scholars think about crime, money, and imperial politics. The ER will bring her expertise on the emerging field of the history of money to the UoB and help the institution strengthen ties with American researchers. COINE’s work programme will also augment the ER’s international research profile and position to obtain a permanent academic position.";183454,8;183454,8;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;THE UNIVERSITY OF BIRMINGHAM;UK;;;;1;0;0;1;0;0 215297;794832;VirtualSync;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;An embodied perspective on anosognosia;2018-10-01;2020-09-30;;"In addition to impairments in episodic and spatial memory, a lack of awareness for one’s memory deficits (also referred to as anosognosia) may be considered a crucial cognitive marker of Alzheimer’s Disease (AD). However, although a growing body of interesting models have been proposed to explain this early symptom, what is still missing is a unifying theoretical framework able to elucidate the complex mechanisms underlying anosognosia. To overcome this issue, it has been recently proposed by the experienced researcher of this project that anosognosia may be related to a break in the synchronization between spatial reference frames (i.e., the Mental Frame Syncing). Starting from these theoretical premises, rooted in neuroscience research field, the major objectives of this interdisciplinary proposal are: a) Investigating the role of “mental frame syncing” in explaining anosognosia in patients with early AD; b) Designing and developing a new “embodied machine” for reducing symptoms of anosognosia; c) Testing the new “embodied machine” (VirtualSync) in a development-of-concept trial for AD patients suffering from anosognosia; d) Disseminating the activities of the project to the scientific/clinical community and to the general public.";175419,6;175419,6;H2020-MSCA-IF-2017;/MSCA-IF-EF-SE;CENTRE HOSPITALIER UNIVERSITAIRE VAUDOIS;CH;;;;1;0;0;1;0;0 214709;772464;THIRST;SIGNED;H2020-EU.1.1.;ERC-2017-COG;H2020;Third Strategy in Tissue Engineering – Functional microfabricated multicellular spheroid carriers for tissue engineering and regeneration;2018-05-01;2023-04-30;;"The field of tissue engineering (TE) pursues a noble goal, driven by the urgent need for tissue and organ repair. It is represented by a fairly large and extremely interdisciplinary scientific community. However, so far TE was not able to deliver to the expectations, with only a few examples of successful clinical translation mostly restricted to a particular disease or tissue type. Despite the fact that all major fundamental bottlenecks of conventional TE strategies have long been identified, a universal solution does not seem to be in sight. In this project I propose to launch a radically new approach, a third strategy in tissue engineering (THIRST), which holds the potential to produce a desperately needed technological breakthrough. THIRST relies on a tissue self-assembly from multicellular spheroids encaged within robust 3D printed microscaffolds. THIRST is enabled by a number of cutting-edge methods, some of which became relevant in the context of TE only recently. In combination, these methods offer a variety of new technological possibilities for the area of TE. The objectives of this project are focussed on establishing the means for automated large-scale production of tissue modules, protocols for microscaffold biofunctionalisation, and demonstrating THIRST potential with highly relevant clinical examples - cartilage, representing avascular tissue, and vascularized bone tissue. A distinct feature of THIRST is its universal applicability, meaning that such a tool-box can be further expanded to encompass other types of tissues without substantial adjustments to the basic tissue assembly procedure. The latter is particularly inspiring, taking into account the considerable regulatory hurdles associated with the development of new TE therapies. Due to its unconventional nature, realization of THIRST relies on overcoming several considerable technological challenges addressed by this project.";1999962,5;1999962,5;ERC-2017-COG;/ERC-COG;TECHNISCHE UNIVERSITAET WIEN;AT;LUDWIG BOLTZMANN GESELLSCHAFT OSTERREICHISCHE VEREINIGUNG ZUR FORDERUNG DER WISSENSCHAFTLICHEN FORSCHUNG;AT;;1;0;0;1;0;0 215651;798514;VARIO;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;The influence of natural pH VARIability on ecosystem response to Ocean acidification;2019-08-01;2021-07-31;;Ocean acidification (OA) threatens the persistence of calcifying marine ecosystems across the planet. Current predictions on the impacts of OA have limited ecological relevance because they are often based on models of the open ocean, where environmental conditions are relatively stable over a diel cycle. However, the majority of vulnerable marine plants and animals exist in nearshore ecosystems where daily fluctuations, resulting from biological carbon production and consumption, can exceed the changes in pH predicted for the end of the century. VARIO will implement a novel approach to elucidate the role of pH variability in shaping the structure and function of a globally distributed ecosystem and its response to OA. VARIO will use rhodolith (maërl) beds in Scotland and Greenland as a model-calcifying ecosystem to characterize the magnitude of natural pH variability inherent in nearshore coastal ecosystems and to explore how such variability may facilitate organismal and ecosystem resilience to OA. VARIO will use an interdisciplinary approach that unites physical and biological oceanography with biogeochemistry to measure natural pH fluctuations and relate that variability with baseline organismal and ecosystem-scale calcification processes. VARIO will then experimentally quantify the effects of OA, overlaid upon natural pH variability, on rhodolith ecosystem structure and function. The findings of VARIO are directly relevant to nations of the European Union, where rhodolith beds are widely distributed and economically valuable. The ecosystem services rhodolith beds afford to the EU, such as supporting commercial fisheries and industry, are directly compromised by OA, and VARIO will provide critical information to inform mitigation and management strategies under OA. By using a globally distributed ecosystem as a model and by incorporating natural pH variability, VARIO will provide the first ecologically relevant context to the impacts OA on nearshore ecosystems.;183454,8;183454,8;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;UNIVERSITY OF GLASGOW;UK;;;;1;0;0;1;0;0 215152;793346;NeuroMag;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Magnonic Matrix-Vector-Multiplier for Neural Network Applications;2018-05-22;2020-05-21;;"Machine learning applications based on artificial neural networks have undergone rapid progress in recent years. To improve the power efficiency over current hardware, alternative implementations of a critical part of artificial neural networks, the matrix-vector multiplier performing large-scale linear transformations, have been intensively researched. Recently, a matrix-vector multiplier based on the interference of optical waves has been proposed in combination with local adjustable electro-optic modulation of the refractive index to enable training. NeuroMag’s objective is to implement such an interference-based matrix-vector multiplier using spin waves (magnons). Magnetoelectric compound materials will be used to engineer scalable broadband transducers with high potential energy efficiency to generate, detect, and manipulate spin waves. Distinct advantages of such a spin wave implementation over a photonic one are (i) the full bidirectionality of the system since transducers can be operated both to excite as well as detect spin waves and (ii) the large tuning range of the phase velocity of spin waves (equivalent to the refractive index in photonics) by the magnetoelectric effect. Magnetoelectric transducers and low-damping Yttrium Iron Garnet magnetic media will be combined to nanofabricate a demonstrator device and study its matrix-vector multiplier operation. Using an interdisciplinary approach that combines materials science, physics, microwave engineering, and device nanofabrication, NeuroMag thus targets the ground-breaking proof-of-concept of a magnonic matrix-vector multiplier and its operation, paving the way towards magnonic artificial neural networks. The combination of learning through research and a comprehensive training plan, including both scientific and technological as well as soft skills, will strongly enhance the researcher profile of the applicant and provide a boost for his future scientific career.";172800;172800;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;INTERUNIVERSITAIR MICRO-ELECTRONICA CENTRUM;BE;;;;1;0;0;1;0;0 215525;797230;3D-Xist;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;3D structure of the long non-coding RNA Xist by complementary cryo-electron tomography and single particle cryo-electron microscopy;2018-05-01;2020-04-30;;"Recent studies have highlighted a pivotal role for long non-coding RNAs (lncRNAs) in normal physiology and disease. As a key example, Xist lncRNA is crucial during the early development of female mammals and is involved in many diseases, e.g. progeria and cancers. To date, cellular and developmental studies have advanced our knowledge of the function of Xist, but a detailed understanding of molecular mechanism is lacking. Therefore, the overarching aim of my proposed research is to directly visualise Xist RNA/ ribonucleoprotein particles (RNPs) in cryo cells at sub-atomic resolution. To this end, I have formulated the following objectives: 1) preparing a cryo sample of mES cells expressing Xist RNA optimised for cryo electron tomography (ET); 2) visualising 3D-Xist RNPs in the mES cell; 3) generating homogenous pseudo-physiological Xist RNPs for single particle cryo-EM; 4) Solving the 3D sub-atomic resolution structure of Xist RNP; 5) Analysing a composite cryo-EM/-ET structure of the Xist RNPs in the mES cell. To achieve this aim, I will employ an interdisciplinary approach including cutting-edge cryo-structural techniques and elegant mES cell biology. My supervisor Prof Brockdorff is a leading scientist in Xist lncRNA research and the host has a state-of-the-art cryo EM facility. The University of Oxford is a world-class research centre, providing excellent transferrable skills trainings and a fantastic infrastructure for career development. The first high-resolution 3D structure of a lncRNA resulting from this innovative research will benefit not only the lncRNA research field, by providing novel molecular insight of the Xist lncRNA, but also the structural biology field, by expanding the 3D RNA structural potential. Dissemination and exploitation of this work, to be achieved by presenting in international conferences and publishing in high-impact open access journals, and communication, through public engagement, are an integral part of this proposed action.";183454,8;183454,8;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;UK;;;;1;0;0;1;0;0 215093;792746;Particle-bound ROS;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Reactive Oxygen Species (ROS) in atmospheric aerosols: exploring formation, sources and dynamics of a new air pollution toxicity metric;2018-05-21;2020-05-20;;"Ambient particulate air pollution is one of the most severe public health issues worldwide as highlighted in a recent WHO study. It is unknown which particle sources and properties are the most health damaging but Reactive Oxygen Species (ROS), present in particles or generated by particle components upon deposition of particles in the human lung, are widely thought to be a significant contributors to particle-related toxicity. However, accurate ROS quantification remains challenging due to the lack of appropriate analytical methods. Recent studies, using novel analytical techniques, found that substantial amounts of particle-bound ROS are present in secondary organic aerosol (SOA). However, it is entirely unknown which SOA precursors and atmospheric conditions affect ROS formation in SOA, especially how anthropogenic pollutants (e.g. NOx and SO2) affect ROS. In this proposal, we aim to establish for the first time a comprehensive data set of atmospheric particle-bound ROS concentrations and temporal variability, measured with high time resolution, by deploying a novel online ROS instrument in two contrasting urban locations in the UK, and to explore how different sources and atmospheric conditions contribute to particulate ROS. Furthermore, we will perform laboratory atmospheric simulation chamber experiments to elucidate ROS formation mechanisms in SOA from anthropogenic and biogenic sources by combining a comprehensive set of novel and state-of-the-art online analytical techniques. The study therefore will provide for the first time knowledge on sources and on characteristics of ROS and will provide essential and critical information for innovative strategies for air pollution mitigation and policies. This interdisciplinary project will provide a unique opportunity for the MSCA Fellow to receive world-class training, to enhance his potential and future career as well as for transfer of knowledge between the researcher and the host.";195454,8;195454,8;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;UK;;;;1;0;0;1;0;0 215203;793826;ROMPAST;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Two Paths of a Shared Past: Memory and Representation of the Nazi Genocide of Roma in Belarus and Lithuania;2018-07-01;2020-06-30;;"The Romani communities of Belarus and Lithuania experienced World War II and the Nazi persecution in similar ways, such as deportations for forced labour, mass murder in the countryside and survival in Soviet partisan units. Throughout the Soviet era, Roma in the two countries faced the same challenges in their commemoration efforts, being denied a public recognition of their suffering. However, an oral history survey shows that there are also considerable differences between the memories of Belarusian and Lithuanian Roma. While Roma from Belarus emphasize their participation in the Soviet partisan units, describing it in the established Soviet patriotic vocabulary, Lithuanian Roma are more likely to underline their suffering and losses, as well as local complicity in their persecution. Why do the Romani minorities of two neighboring post-Soviet states make sense of their shared past so differently? This study suggests that the key to understanding this phenomenon lies in the socio-political context of memory work. Drawing on the post-Soviet transformations, official memory and minority politics in Belarus and Lithuania, this interdisciplinary research project compares the memory trajectories of Roma in these countries. It pays equal attention to the memories of “ordinary” Roma and Romani activists and the public representation of the Nazi genocide of Roma. Theoretically, this study seeks to understand how the processes of social exclusion and inclusion work at the level of memory and commemoration, and in what ways memory of the bitter past affects the identity of an ethnic group.";171460,8;171460,8;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;Stiftung zur erforschung von Ost-und Suedosteuropa;DE;;;;1;0;0;1;0;0 214522;798560;DNAProteinCrossRep;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Identification of DNA-Protein-Crosslink Repair Factors;2018-06-01;2020-05-31;;DNA damage can cause mutations and genome instability and is therefore the underlying cause of many pathologies including neurodegeneration and cancer. To maintain genome integrity, cells are equipped with sophisticated pathways for efficient repair of the broad spectrum of lesions that frequently arise in cellular DNA. By now, most DNA repair pathways are well understood. However, dedicated mechanisms for the repair of DNA-protein crosslinks (DPCs) have only been discovered very recently and are still poorly described. This is mainly due to a lack of approaches for specifically generating DPCs. My host lab has established a cell-based system that facilitates, for the first time, the induction of genome-wide yet defined DPCs. With this system at hand, I propose a project to identify and characterise cellular responses to DPCs in both human cells and in the nematode Caenorhabditis elegans (C. elegans). I will utilize the newly established system in a CRISPR/Cas9-based genome-wide screen to identify new DPC repair factors, and subsequently characterise their roles in promoting genome stability. I will strengthen the physiological relevance of my findings by studying orthologues of selected factors in C. elegans, in order to gain insights into their tissue specificity and roles in development and organismal fitness. By combining the host lab’s strong standing within the DNA repair field and formidable know-how in the area of cell-based studies of DNA damage repair pathways with my expertise in DNA damage research in C. elegans, I will be in a unique position to critically advance our knowlegde about DPC repair. Considering that DPCs are generated by many anti-cancer drugs, it is particularly important to illuminate the underlying repair mechanisms to improve current treatment strategies. This timely and interdisciplinary project will greatly enhance my scientific and transferrable skills required to realize my long-term goal of becoming an independent group leader.;212194,8;212194,8;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;KOBENHAVNS UNIVERSITET;DK;;;;1;0;0;1;0;0 215522;797209;FIBROSIS;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Fibroproliferative Invasive Fibroblasts in Idiopathic Pulmonary Fibrosis;2018-09-03;2021-09-02;;"Idiopathic Pulmonary Fibrosis (IPF) is a relentlessly progressive, lethal, lung disease with a uniquely poor prognosis. Patients typically die within 2-5years of diagnosis and IPF’s European incidence is increasing while effective therapies for improving survival remain elusive. IPF is a disease in which the normal wound healing responses are dysregulated leading to fibrosis and loss of gas-exchange regions in the lung rather than restoration of normal lung structure and function. Recently discovered invasive fibroblasts are believed to be central to the progressive fibrogenesis observed in IPF by contributing to an accumulation of fibroblasts in the injured lung and augmenting the destruction of normal alveolar structure. However the source of these invasive fibroblasts and what makes them so uniquely pathogenic is unknown. On this project I will work with Prof. Paul Noble, Cedars-Sinai Medical Centre, USA, one of the world’s leading IPF researchers and Ireland’s leading respiratory researcher Prof. Paul McLoughlin, University College Dublin, Ireland. The objectives of this project are to investigate: (1) the phenotype and behaviour of the invasive fibroblast from human IPF donors in vitro; (2) delineate the molecular pathways that make invasive human IPF fibroblasts uniquely pathogenic using state-of-the-art single cell RNA-sequencing; (3) determine the source of invasive fibroblast accumulation in the IPF lung using the most advanced lineage tracing methods available in a cutting-edge genetically modified mouse model. This interdisciplinary proposal will merge skills I have acquired with the latest technologies across multiple disciplines in world leading international institutions to explore the complex molecular basis of IPF. The results of this proposal will generate significant impact in the IPF field and will be directly applicable to the specific challenge highlighted in the H2020 Work Programme: Diagnostic characterisation of rare diseases.";266063,4;266063,4;H2020-MSCA-IF-2017;/MSCA-IF-GF;UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN;IE;;;;1;0;0;1;0;0 214440;795271;CommGenRwa;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Genocide Commemoration in the Rwandan Diaspora;2018-09-01;2020-08-31;;"This project explores commemorative responses to the 1994 Genocide against the Tutsi in Rwanda, seeking to build an understanding of the forms of commemoration taking place among Rwandan genocide survivors living in the diaspora. Focusing on three European case study areas – Belgium, France and the UK – it will examine the myriad ways in which community groups, authors, artists and creative practitioners are communicating their experiences of violence and exile to the host societies, and will investigate the impact of place and displacement on commemorative practices within diasporic communities. As the 25th anniversary of the 1994 Genocide against the Tutsi in Rwanda approaches, this project will make an important and timely contribution to the field of Cultural Memory Studies, advancing new critical paradigms – conceptualised in terms of a particular form of ‘exilic memory’ – for understanding the articulation and transcultural circulation of memory in specific diasporic locations. It is significant that the project will be completed in Belgium, given the colonial history shared by the two countries. The primary outputs of the project will include the completion of a monograph, the organisation of an interdisciplinary symposium and the curation of an exhibition at the Royal Museum for Central Africa in Brussels, which will feature the work of Rwandan diasporic artists and writers. These dissemination and outreach activities, combined with the personalised training offered by Ghent University’s Postdoctoral Talent Management programme, will enable the researcher to acquire new competencies and multidisciplinary knowledge and to further enhance her scholarly profile and publications, which will be crucial for reaching a position of professional maturity. The MSCA-IF at Ghent University will also offer the researcher the opportunity to establish international collaborations in her field and will facilitate outstanding intellectual exchange.";160800;160800;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;UNIVERSITEIT GENT;BE;;;;1;0;0;1;0;0 214820;786381;P-LH2;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Characterisation of pressurised liquid hydrogen (LH2) releases;2018-09-03;2020-09-02;;"Hydrogen and fuel cell technologies were identified amongst the new energy technologies needed to achieve up to 80% reduction in greenhouse gases by 2050 in the European Strategic Energy Technology Plan. This is not only for automotive applications but also for distributed energy storage and power to gas technology. The transport of liquefied hydrogen (LH2) is considered as the most effective option for scaling up the hydrogen supply infrastructure. However, LH2 implies specific hazards, which are very different from those associated with the relatively well-known compressed gaseous hydrogen. Experience with LH2 in a distributed energy system is lacking. The release of pressurised LH2 jet is accompanied by flashing, intense phase changes, cryogenic jets, droplets, spray and rainout, etc. The wide flammability range of hydrogen and low ignition energy further necessitate special consideration for fire and explosion safety. P-LH2 aims to develop robust modelling strategies for pressurised LH2 jets; and to train the Experienced Researcher (ER) and develop a two-way transfer of knowledge in an interdisciplinary project. To achieve these overall goals, the following five specific objectives are specified: 1. Develop and validate a robust solver LH2FOAM within the frame of OpenFOAM® for pressurised LH2 jets to assist facility siting and safe operations of LH2 technologies in transport, storage and utilization in the forthcoming upscaling of hydrogen supply infrastructure and the development of LH2 specific international codes and standards; 2. Establish the principle structure, morphology and behaviour of LH2 jets in realistic conditions including flammable envelope; 3. Investigate effect of wind speed and direction, confinement and obstacles on large-scale LH2 releases; 4. Foster a two-way transfer of knowledge between the ER and participating organisations; and 5. Disseminate and communicate the P-LH2 results to wider audiences in order to maximise its impact.";195454,8;195454,8;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;THE UNIVERSITY OF WARWICK;UK;;;;1;0;0;1;0;0 214818;786281;GAAL;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Of Awful Connections, East German Primitives and the New Black Berlin Wall: Germany and German History in African American Literature, 1892-2016;2019-06-01;2021-05-31;;"Darryl Pinckney’s “Black Deutschland” (2016), Paul Beatty’s “Slumberland” (2008), and John A. Williams’ “Clifford’s Blues” (1999) are three recent novels by African American authors and with African American protagonists that are partly set in Germany and that include references to events of German history such as the Holocaust and German Reunification. The research action will take these three novels as points of departure for an investigation that combines an accurate analysis of the images and functions of Germany and German history in African American literature with a transnational, comparative perspective. Drawing on a theoretical framework that connects comparative imagology, black diaspora studies, and the recent academic focus on world literature's “multidirectional memory” and its “cosmopolitan style”, the project will analyze four historically diverse, cross-cultural discourses that have shaped the role of Germany and German history in African American literature: 1) the formation of a ‘canonic’ African American image of postromantic Wilhelminian Germany that can be traced back to Du Bois’ time as a student in Berlin (1892-94); 2) the interwar period and its intertwining sub-discourses of the Old World as “racial haven” for African Americans, and of Berlin as “European capital of sexual libertinage”; 3) National Socialism and its relations and parallels to racism in the U.S.; 4) African American perceptions of Germany as a divided and/or reunified country. The project is based at two institutions in Berlin: the interdisciplinary Zentrum für Literatur- and Kulturforschung (ZfL), where the applicant will be part of the research area on world literature, and the Kennedy Institute for North American Studies at the FU Berlin, where a secondment will take place. The project's location in the German capital, which is in itself a major topic of the research action, will be a connecting factor for numerous networking, dissemination and communication activities.";171460,8;171460,8;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;GEISTESWISSENSCHAFTLICHE ZENTREN BERLIN EV;DE;;;;1;0;0;1;0;0 214905;787956;NUCLITEX;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Producing transnational nuclear expertise in Italy (1955-1987): a historical-ethnographic approach;2019-06-03;2021-06-02;;"Focusing on the case of nuclear power in Cold War Italy, this research project analyses the transnsation dynamics of knowledge production involving political elites, official and unofficial scientific experts, the associative milieu, and the public sphere. It covers the period going from the beginning of Italy’s nuclear programme in the early 1950s, to the referendum of 1987 that marked the end of Italy’s nuclear programme. It investigates how Italian experts and counter-experts built their own knowledge(s) through weaving transnational links with other European countries and with the USA; how they navigated forms of public engagement to advance or challenge nuclear power programmes; and how they tried to produce and legitimate, or dismiss, alternative types of knowledge and expertise on the environmental and health risks of nuclear energy in Italy. While it focuses on an existing trend in the science and technology studies, it does so in relation to a EU country – Italy - a historical period – post-1960s - and a form of energy – nuclear - that have not yet been explored by academic studies. By adopting an interdisciplinary approach joining methods and theories from the history of technology and the STS, the project intends to enable academics and analysts to understand more fully the interactions between officials, scientists, and publics in nuclear affairs.";158121,6;158121,6;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;UNIVERSITAT AUTONOMA DE BARCELONA;ES;;;;1;0;0;1;0;0 214908;788042;REACTOMEgsa;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Extending the REACTOME Pathway Database for multi-omics biomedical data analysis;2018-08-01;2019-07-31;;"The increasing availability of high-throughput ‘omics technologies results in unprecedented opportunities for precision medicine and biomedical research. With the increasing availability of large amounts of data (‘big data’), data analysis and interpretation have become a major bottleneck. Pathway analysis techniques are used to incorporate existing biological knowledge into the data analysis and allow researchers to focus on the interpretation of regulated biological processes. Despite the existence of many advanced pathway analysis algorithms, most leading pathway analysis resources still rely on simplistic ‘gene set over representation’ analyses (ORA) and cannot integrate data from different ‘omics approaches. Reactome is one of the most popular resources for pathway information. Its open-access data model, powerful web interface, and stringent manual curation and peer-review provide an ideal foundation for this project’s developments. In this project, I will extend Reactome towards an analysis platform for multi-omics biomedical studies. I will replace its current ORA approach with more sophisticated pathway algorithms supporting transcriptomics, microarray, proteomics, and metabolomics data. Next, I will extend Reactome to analyse datasets of samples that cannot be attributed to a phenotype. The extended version of Reactome will be able to derive one expression value per pathway which can then be correlated with clinical parameters to identify clinical relevant biological processes. This will make Reactome a prime resource for multi-omics biomedical studies. I anticipate that the successful completion of this project will allow me to integrate and extend my current skills as a medical doctor and a bioinformatician towards systems biology studies. The additional gained experience in project management and communication of scientific results will form the basis for my envisaged career to start my own interdisciplinary biomedical research group.";97727,4;97727,4;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;EUROPEAN MOLECULAR BIOLOGY LABORATORY;DE;;;;1;0;0;1;0;0 214458;795707;Cosmo-Blow-Up;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Deflating the blow-up: controlling infinities in cosmic fluid descriptions;2018-12-01;2020-11-30;;"'According to the standard model of cosmology, we are witnesses of an epic battle: While dark energy leads to an accelerated expansion, matter and particularly the dark matter, opposes this trend, leading to the observed large-scale structure of the Universe. Since the pioneering discovery of dark energy that lead to a Nobel Prize in Physics, the nature of dark matter is still shrouded in mystery. What we know is that matter can be described as a fluid on macrophysical scales, and that the fluid has, at early times, no overlapping matter trajectories. Yet, matter trajectories do eventually begin to intersect ('shell-crossing'), which marks the starting point of very complex computations in the phase-space on the one side, and the birth of our cluttered Universe on the other side. Understanding the collapse and shell-crossing is quite a challenge that is usually tackled by utterly opposing means, either by (approximative) analytical models or by cosmological N-body simulations. With this Marie-Curie fellowship, I will close this gap and get full control of the instant of shell-crossing in two complementary ways. I will develop full-fledged numerical simulations of the cosmological fluid equations and develop certain matter collapse models, that, at their heart, determine the matter trajectories by exact analytical descriptions until the instance of shell-crossing, where infinities become real and the solutions 'blow up'. Detecting blow-ups is one of the most challenging and rewarding problems in mathematical physics; by resolving them, precious information will be gained which we will use to improve (heavily used) N-body simulations at the critical vicinity of shell-crossing. The department Lagrange (host institute) is a unique place in Europe that houses both world experts in numerical cosmology and in mathematical analysis, thereby complementing exactly my expertise (exact analytical models). This allows us to solve outstanding problems in interdisciplinary fields.'";185076;185076;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FR;;;;1;0;0;1;0;0 215044;792172;Learn2;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Learning and Being in Sport: A Phenomenological Investigation;2019-03-01;2021-02-28;;"Although sport is habitually promoted as an important context for positive youth development and learning, there is a lack of understanding of what learning in sport is and how it shapes and is shaped by the learner’s identity, values, and socio-cultural situatedness. Using an existential-phenomenological approach, we theorise and explore student-athletes’ learning experiences in sport, providing knowledge that is radically innovative and helps to validate experiential learning in sport. The study responds to European Union initiatives to safeguard the development of talented youth athletes and validation of informal and non-formal learning. Eighteen Finnish student-athletes (10 women) aged 18-19 will participate in hermeneutic interviews focused on clarifying meaning in their learning experiences in sport. Drawing on Structural Existential Analysis, we seek to uncover the essential – yet always situated – structures of athletes’ learning experiences. We also explore gender dimension of learning and sporting experiences. Based on the findings, we will propose a framework for further research and provide recommendations for policy and practice. The findings will be valuable for educational institutions and dual career service providers, as well as sport coaches and student-athletes to support athletes’ future employability and transition into the labour market. The existential-phenomenological perspective offers a novel methodological approach and our study involves a truly interdisciplinary research team (developmental and cultural psychology, existential philosophy, and phenomenological sociology). The project offers training for the experienced researcher in research and transferable skills as well as gender issues, and knowledge transfer through secondment, research visits, and seminars. The project provides the experienced researcher with the possibility to reinforce a position of professional maturity and become a research leader in the subject area.";179325,6;179325,6;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;JYVASKYLAN YLIOPISTO;FI;;;;1;0;0;1;0;0 215426;796215;MediterraneanGypsies;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Mediterranean Gypsies. A forgotten history beyond diaspora, nomadism, marginality in three Western Mediterranean areas of the Spanish Crown (Andalusia, Sicily, Sardinia, 16th- early 18th century);2018-09-10;2020-09-09;;"Thanks to the collaboration in Leeds between an expert in Gypsy and Italian history (the fellow, Dr Aresu, who will restart his academic career) and a scholar in modern Spanish history (the supervisor, Dr Alonso), MediterraneanGypsies aims at a rethinking of the way the history of Gypsy people has been framed to date. It proposes an innovative interpretative paradigm, which it applies to a specific study case: Gypsy mobility in three Western-Mediterranean areas of the Spanish Crown (Andalusia, Sicily, Sardinia) in the modern era (16th, 17th and early 18th century). Traditional reconstructions, based mainly on institutional repressive documents (e.g. acts of the Inquisition), have privileged a reductive vision of the Gypsies as a diasporic, nomadic, marginal minority that was relentlessly persecuted. By building on his previous researches, Dr Aresu will analyse instead a broad range of primary sources, mostly unpublished - from custom records to notarial deeds and parish funds -, that he will collect via an extensive archival search in Madrid, Sevilla, Palermo, Cagliari and in the Romani Collection of the University of Leeds. With an interdisciplinary approach that intersects transnational history, micro-history and historical anthropology, the project will investigate the economic and social relations of Gypsy groups both among themselves and with the other residents, scrutinise their articulated relationships with the local and state institutions, and insert their mobility strategies within the broader circulation processes existing throughout the Mediterranean as a whole. A special focus will be on the role of women, in order to challenge the mono-dimensional image of the Gypsy fortune-teller and enchantress. Beyond its scholarly value, the project will produce and disseminate alternative narratives on Gyspy history, which can potentially counter the worrying anty-gypsyist discourses that still have currency in parts of contemporary European society.";195454,8;195454,8;H2020-MSCA-IF-2017;/MSCA-IF-EF-CAR;UNIVERSITY OF LEEDS;UK;;;;1;0;0;1;0;0 215032;792006;GENTES;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Genesis of Ethnicities and Nations in Textual Evidence for Scandinavia, c. 750-c. 1000;2018-09-01;2020-08-31;;"Traditional narratives of Scandinavian history generally see the early Middle Ages, or ‘Viking Age’, as the period in which the three kingdoms of Norway, Denmark and Sweden were created (or ‘unified’). Such narratives draw mainly on the 13th-century Icelandic Sagas, written several centuries after the events they portray. This project will challenge these narratives by developing and testing two hypotheses: 1) That contemporary and near-contemporary sources, rather than the sagas, should provide the basis of Scandinavian history between c. 750 and c. 1000; 2) That Scandinavia should be examined as a unit in this period, and that later borders and ethnic identities should not be projected into the past. To do so will require a critical re-evaluation of the written sources for the period. The objectives of the project will thus be to investigate five key areas: 1) Bias and sources of information in contemporary and near-contemporary written sources; 2) The assessment of the sources, methods and agendas of twelfth-century Scandinavian texts; 3) The dating and transmission of Old Norse verse; 4) The reliability of the Icelandic Sagas; 5) The harmony of the resulting picture with archaeological evidence. These objectives will be achieved through an interdisciplinary, critical approach to the sources that will draw on historical, literary, philological and text-critical techniques. The sources will be studied in a European context, rather than a national or exclusively Scandinavian one. By drawing on the debate about ‘ethnogenesis’ that has transformed our understanding of Continental European history in the Migration Age, the project will present Scandinavia’s earliest history through a non-national lens. The resulting research will contribute to both scholarly and popular debates about historical identities and their (mis)use by nationalisms, which will be extremely timely, given the intensification of these debates in the wake of the refugee crisis and Brexit.";178156,8;178156,8;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;OESTERREICHISCHE AKADEMIE DER WISSENSCHAFTEN;AT;;;;1;0;0;1;0;0 214419;795310;CliRSnow;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Statistically combine climate models with remote sensing to providehigh-resolution snow projections for the near and distant future.;2018-10-01;2020-09-30;;The cryosphere in the European Alps is expected to change substantially with global warming. Snow in the Alps impacts the local communities but also affects the quantity and seasonality of water downstream, and thus has a wide range of effects on agriculture, ecosystems, hydropower, and tourism. Projections of future snow are required in society and economy. Targeted actions require information at the local community scale, which is not yet consistently available for the whole Alpine region. This is because the existing approaches to infer future snow conditions rely on physical models, either regional climate models (RCMs) or snow-hydrological models, which are both computationally very intensive, making it yet impossible to have a high resolution output for such a large area as the Alps. Here, I shall employ empirical models derived from remote sensing (RS) to provide an innovative and fast solution to increase the precision in future projections of snow cover from RCMs for the whole Alpine area. This will be achieved by correcting the bias in snow cover from RCMs and increasing the spatial resolution with RS snow cover data. Such an approach has now become feasible, because the data that forms its basis is on the verge of being sufficient in time (RS: MODIS time series since 2000) and space (RCM: EURO-CORDEX horizonzal resolution at approx. 12.5km). The host has the necessary data (daily MODIS snow cover at 250m and output from 15 different RCMs with snow cover), the technological environment for the computational demand, and the relevant expertise in each discipline (remote sensing, climate, hydrology) inside the institute and with international partners. I shall bring the statistical background, data handling skills, and interdisciplinary experience to combine these fields. This fellowship shall pave the way for my future career as independent researcher, but also produce output ready for re-use and exploitation by stakeholders in the Alpine countries.;180277,2;180277,2;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;ACCADEMIA EUROPEA DI BOLZANO;IT;;;;1;0;0;1;0;0 215508;797049;RET PHOTOSWITCH;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;THE DEVELOPMENT OF NOVEL PHOTOSWITCHABLE KINASE INHIBITORS;2018-10-01;2020-09-30;;"The overall research objective of this project is to develop novel photoswitchable kinase inhibitors (PKIs), targeting on REarrange during Transfection (RET) for use in living cells and in zebrafish (Danio rerio). Controlling the action of kinases in a reversible way will have an exceptional potential for investigating signal transduction in zebrafish. In this work, photoswitchable RET kinase inhibitors based on azo-functionalized pyrazolopyrimidines will be developed, enabling photonic control of RET activity with substantial differences in inhibitory activity between the two photoisomeric forms. Such RET inhibitors are currently not available. RET is expressed by the immune cells of the brain, the microglia and is mediating activation of the cells. Microglia has been shown to be responsible for both protecting and harmful effects in neurodegenerative disorders. Although RET has been shown to be involved in neurodegeneration, its role in Alzheimer’s disease (AD), where microglia play an important role, is not known. The ability to manipulate the activity of RET using light would result in temporal control of enzymatic activity, thus serving as a valuable molecular tool to study the function of RET in microglia cells and further our understanding of AD. The research project is (1) highly interdisciplinary, (2) timely due to the recent interest of photopharmacology and (3) innovative by combining zebrafish imaging with photopharmacology to study signalling relevant for development of AD. This fellowship will ensure the best possible career opportunities for me as I will receive substantial training in cutting-edge approaches, gain mentor and supervision skills, presentation skills and critical assessment skills, largely expand my collaborative network, and gain the fundaments for becoming a mature, independent researcher within the field of chemical biology.";185857,2;185857,2;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;GOETEBORGS UNIVERSITET;SE;;;;1;0;0;1;0;0 215368;795615;STELLAR;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;multireSponsive hybrid Transition mEtaL dichaLcogenides-bAsed optoelectRonics – A European Fellowship for career development;2018-12-01;2020-11-30;;STELLAR will offer world-class training through research in the cross-disciplinary and supra-sectorial field of 2D transition metal dichalcogenides (TMDCs)-based multiresponsive optoelectronics to an extremely talented and promising young researcher, with a PhD in physics and an extraordinary track record. The proposed research lies at the interface between physics, chemistry and electrical engineering, in the interdisciplinary realms of supramolecular sciences, materials science and nanoscience. The overall mission is to train the fellow to become an independent scientist and to prepare him for a leading position in academia/public sector or industry. The research programme in STELLAR targets a fundamental breakthrough in the field of 2D TMDCs by combining switchable molecular systems to construct multiresponsive hybrid molecules/TMDC structures and optoelectronic devices. For this purpose, TMDC nanosheets will be engineered via ion bombardment to create chalcogen vacancies as anchoring sites for molecules. Specially designed molecules with multiple responsive moieties (photochromic and electrochemically switchable moieties) and suitable head groups (thiol or selenol groups) will be chemisorbed on the defective TMDC surface. This novel hybrid system can respond to multiple independent external stimuli and exhibit distinct physical and chemical properties in different stable states. Electrolyte-gated field-effect transistors (FETs) with a hybrid molecules/TMDC channel will be exploited to realize multiresponsive optoelectronic devices. These FETs can be controlled or switched not only by gate voltage, but also by multiple external stimuli. Such smart devices can work as multi-bit memories, chemical sensors and diodes. In conclusion, STELLAR aims at developing high-performance multiresponsive optoelectronic devices with hybrid molecules/TMDC systems to replace the state-of-the-art Si-based and organic electronic devices.;173076;173076;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;UNIVERSITE DE STRASBOURG;FR;;;;1;0;0;1;0;0 214350;786490;BRAD;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Brexit and Deportations: towards a comprehensive and transnational understanding of a new system targeting EU citizens;2018-11-01;2020-10-31;;With Brexit and the abandonment of the free movement and residence principle, the UK will define its new immigration policy concerning EU nationals. The new immigration policies will aim to control and circumscribe the mobility of the citizens of the EU member states, currently free to travel, live and work in the UK. They may also be returned or deported only under very specific circumstances. Following Brexit, those who will not comply with the new regulations will become deportable. The aim of the project is to research the implementation of the new UK deportation system concerning EU nationals. The fellow will propose a comprehensive approach to the UK deportation regime, taking into account its various components: (1) immigration policies, (2) agencies that enforce them, (3) public debate that accompanies changes in migration policies and their implementation, (4) migrants that become deportable and are deported, as well as (5) return migrants and stayers back in sending countries who consider migrating to the UK and who adjust their (im)mobility strategies according to, or resisting, migration policies. The project assumes that the deportation regime is a transnational phenomenon, since it concerns not only people in migrant-receiving countries, but also in migrant-sending counties. The research offers an analysis of the largest migrant group in the UK, the Poles. The case of the Polish migrants will offer an insight into how the transnational UK deportation regime becomes rooted among migrants and develops back in their hometown communities. The project draws upon interdisciplinary qualitative methodologies, including multi-sited ethnography, Critical Discourse Analysis of media, and legal analysis. Its outcomes will reach EU, UK and Polish policy makers, influential think tanks, the academic community and the general public.;195454,8;195454,8;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;UNIVERSITY OF WOLVERHAMPTON;UK;;;;1;0;0;1;0;0 215287;794700;NLR_NLR-ID power;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;NLR-ID diversity, mechanism and functionality upon transfer between species;2018-05-01;2020-04-30;;"Plant and animal innate immune systems detect pathogen infection by both cell-surface PRR (pattern recognition receptor) and intracellular NLR (nucleotide-binding leucine-rich repeat) immune receptors, and activate effective defences. Transfer of cell surface receptors between plant families can enhance disease resistance, but intracellular receptors are often non-functional when transferred to different families. This 'restricted taxonomic functionality' may arise from a requirement for an appropriate helper or partner NLR. Some NLRs carry Integrated Domains (IDs) that serve as “baits” that detect the action of pathogen effector proteins, thus enabling pathogen recognition. NLR-ID proteins require for function a helper NLR, usually closely linked as a head-to-head gene pair. Some NLR/NLR-ID pairs confer resistance to diverse pathogens when transferred as a unit between plant families. For example, Arabidopsis RPS4/RRS1, when transferred as a unit, confers recognition of bacterial and fungal pathogens in Solanaceae and cucurbit plants. This project is based on the hypothesis that NLR/NLR-ID pairs from one species can detect effectors that target that class of ID from a pathogen of any species. Rice is completely resistant to fungal rusts of wheat and barley. Many NLR-IDs are present in rice but not in other Poaceae. My goals are to: (i) use DNA sequence capture and bioinformatics to discover the full NLR/NLR-ID pair repertoires of diverse rice genotypes; (ii) investigate rice IDs interactions with effectors from wheat and barley pathogens; and (iii) transfer gene pairs to barley, maximizing the diversity of IDs in these pairs, and assess transgenic lines for novel resistance to barley diseases. The outcomes of this interdisciplinary Fellowship will provide profound insights into NLR/NLR-ID diversity in plants, into the diversity of domains that are effector targets, and into the molecular basis of 'non-host' disease resistance.";195454,8;195454,8;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;THE SAINSBURY LABORATORY;UK;;;;1;0;0;1;0;0 214371;797058;CaMMEgy;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Christians among Muslims in Medieval Egypt;2018-10-01;2020-09-30;;"The CaMMEgy project aims at studying the adaptation processes of the Coptic Christian population after the Arab conquest of Egypt (642 CE) under an innovative angle. It will focus on discourse strategies set up by members of this community in order to claim and reinforce a favourable position in a social and territorial context that was gradually reorganized by Muslim rulers. The analysis will be based on data extracted from two largely understudied textual corpuses that are rarely mobilized together. The first corpus is the Coptic-Arabic historiography and is constituted by historical texts written in Arabic in a Coptic ecclesiastical milieu after it had been arabicized, from the 11th century onwards. The second corpus – papyrological sources – consists mainly of fiscal, legal and epistolary documents, mainly written in Arabic (but also Greek and Coptic). As products of daily interactions between the various members of the Medieval Egyptian society, they will allow to assess the historical reliability of data coming from the first corpus and to consequently highlight the abovementioned strategies. The research will be interdisciplinary and will combine the historical approach, led by Prof. Mathieu Tillier (the supervisor), with the perspectives of textual criticism, (socio)linguistics and literary analysis, provided by Dr. Perrine Pilette (the experienced researcher), at the Université Paris-Sorbonne. Next to peer-reviewed articles that will be uploaded on an open-access repository at the date of publication, one of the main outputs of the CaMMEgy project will be intended for the use of both the academic and general public: new geo-historical maps of Egypt and the Coptic territory – real or purported – will be drawn and uploaded on an open-access web platform.";173076;173076;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;SORBONNE UNIVERSITE;FR;;;;1;0;0;1;0;0 215289;794761;HI_IM_NEUROSOCIETY;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;HIstory and IMpact of NEUROimaging on SOCIETY;2019-09-01;2021-08-31;;"The development of neuroimaging techniques, such as computed axial tomography (CAT scanning), functional magnetic resonance imaging (fMRI) and positron emission tomography (PET), has been one of the major biomedical achievements of the past hundred years. These techniques allow the in vivo visualisation of the brain and gave new impetus to medicine, neurology, psychiatry, psychology, philosophy, economics and related fields by providing two unprecedented types of insight. Nations worldwide are making unprecedented investments in neuroimaging-related research: key projects include the European Human Brain Project, which is a H2020 FET Flagship Project (started in 2013, $1.2 billion), the US BRAIN Initiative (2013, $1 billion) and the Japanese Brain/MINDS (2014, $310m). Neuroimaging breakthroughs are making history, but the history of neuroimaging needs to be comprehensively assessed and the impact of neuroimaging on our society still needs to be properly defined. These are the key aims of this MSC Action, which is aimed at developing the first interdisciplinary platform worldwide on the history and impact of neuroimaging. Investigating neuroimaging in a historical perspective will fundamentally contribute to an integrated understanding of how neuroimaging has been shaping and is shaping biomedicine, culture and society. A critical history of the ways in which we see and study the brain is also crucial to increase the awareness about past and current research with neuroimaging, to involve the general public in a constructive debate about neuroscientific and societal challenges, and to promote a scientific culture about neuroimaging techniques and their applications.";168277,2;168277,2;H2020-MSCA-IF-2017;/MSCA-IF-EF-SE;OSPEDALE SAN RAFFAELE SRL;IT;;;;1;0;0;1;0;0 215083;792674;RuZn;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Ru–Zn Heterobimetallic Complexes;2018-06-01;2020-05-31;;Fedor Miloserdov (FMM, the fellow) alongside Prof. Mike Whittlesey (MKW, University of Bath, UK) designed the RuZn proposal that deals with heterobimetallic late transition metal – Lewis acidic metal complexes, particularly ones featuring an unsupported Ru–Zn bond. Having similar properties with other Pt-group metals, Ru is more than order of magnitude cheaper. The cooperativity between Ru and Lewis acidic metal (Zn) can enhance the stability, selectivity and reactivity of the catalytic system and lead to new catalytic applications of ruthenium complexes, making them more appealing for both academia and industry. The rationale for the RuZn project is the 2016 report by MKW on the convenient approach to a novel complex with an unsupported Ru–Zn bond. FMM is going to synthesize a family of new Ru–Zn complexes with different ligand environments and systematically study their reactivity and stability in order to find suitable catalytic applications. The RuZn proposal aims not only at developing a new range of ruthenium catalysts, but will also provide FMM a unique opportunity to work on the cutting edge of science, as well as improve his skills in leadership, teaching, mentoring and grant-management. As an interdisciplinary part of the program, FMM will have a secondment with Prof. Stuart Macgregor (SAM) at Heriot-Watt university (Edinburgh, UK), where he will acquire knowledge in computational chemistry while studying the Ru–Zn bonding and reactivity.;183454,8;183454,8;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;UNIVERSITY OF BATH;UK;;;;1;0;0;1;0;0 215144;793228;POLYFIL;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Polychromatic low-threshold fibre laser;2018-09-01;2020-08-31;;"The ultimate goal of the proposed project Polychromatic low-threshold fibre laser (POLYFIL), is to train a talented researcher with high potential through a research focused on the development of a new type of fibre lasers based on innovative technique of the controlled light localisation. The success of this interdisciplinary project will lead to a novel attractive fibre laser design with multiple localisation-based characteristics including prescribed polychromatic lasing frequencies with disciplinary lasing energies, extremely low threshold and stable lasing output. The Fellow, Dr. Hongwei Yin will be trained in the emerging field of science, technology and industrial applications of new types of photonic and fibre-optic polychromatic devices at the Aston Institute of Photonic Technologies (AIPT) (host - Dr. Turitsyna) and the EU industrial secondments: sensing - FOCUS (Dr. Martín-Lopez), medical photonics - ARTPHOTONICS (Dr. V. Artjushenko) and food industry - BRANSCAN (Dr. A. Erdentug). The Fellow will transfer to the EU partners important knowledge of advanced numerical techniques and new designs of photonic devices. The POLYFIL outputs will be valuable to the EU photonics industry by offering the extremely low threshold polychromatic fibre laser that is of interest for a range of applications varying from laser science, quantum technology, and optical communication, to medical applications and optical sensing with a special focus on food industry. The technology resulted from the POLYFIL outputs will contribute to the enhancement of EU scientific excellence. An important outcome will be the formation of a strong long-term collaboration network between the Fellow’s host university in China, AIPT, FOCUS, ARTPHOTONICS and BRANSCAN, bringing together the European and Chinese research centres of excellence. Overall, POLYFIL will contribute to European leadership in advanced photonics research and technology.";195454,8;195454,8;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;ASTON UNIVERSITY;UK;;;;1;0;0;1;0;0 215195;793769;ION;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Information Diffusion on Networks;2019-02-01;2021-01-31;;"This two-year research project aims to analyse the simultaneous diffusion of multiple pieces of information on (social) networks; how messages may interact, how rumours diffuse in the presence of truthful information and verification, and how network structure interacts with the virality of information. Misinformation can have severe consequences, such as the debunked myth of a link between vaccinations and autism or AIDS denialism. Political examples also abound. The rise in communication through online networks is often quoted as contributing to an increased spread of rumours and misinformation. Yet, in truth the state of the art has little to say about how alternative pieces of information interact on networks, and even less why rumours might be propagated without prior verification. This project aims to build rigorous economic models which can shed light on the processes and decisions involved, thus addressing the tangible threat that the spread of misinformation poses to society. I am an experienced researcher and have worked for various years in the area of information diffusion on networks, providing me with excellent insights and methodological tools to work on this project under the supervision of Professor Sergio Currarini, a leading expert in network theory. My stay at Ca’Foscari University of Venice will allow me to establish new (international) collaborations and additional training, particularly regarding interdisciplinary tools to bring to the economic study of (mis)information diffusion. Together the training, network, and publications inherent in the development of this project will have an extremely positive impact on my career, including increased possibilities to apply for future funding calls by the EU. By forming the basis of a long-run research agenda focusing on online information diffusion the project will contribute to the EU’s Digital Market Strategy and to its international reputation as a world leading research destination.";180277,2;180277,2;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;UNIVERSITA CA' FOSCARI VENEZIA;IT;;;;1;0;0;1;0;0 214675;771640;NeoplAT;SIGNED;H2020-EU.1.1.;ERC-2017-COG;H2020;Neoplatonism and Abrahamic Traditions. A Comparative Analysis of the Middle East, Byzantium and the Latin West (9th-16th Centuries);2018-05-01;2023-04-30;;"NeoplAT offers a fresh and thoroughly documented account of the impact of Pagan Neoplatonism on the Abrahamic traditions. It focuses mainly, but not exclusively, on the Elements of Theology of Proclus (fifth century) which occupies a unique place in the history of thought. Together with its ninth-century Arabic adaptation, the Book of Causes, it has been translated, adapted, refuted and commented upon by Muslim, Jewish and Christian thinkers across centuries, up to the dawn of modernity. Despite a renewed interest in Proclus’ legacy in recent years, one still observes a tendency to repeat conventional hypotheses focused on a limited range of well-studied authors. This project radically challenges these conservative narratives both by analysing invaluable, previously ignored resources and by developing an innovative comparative approach that embraces a variety of research methods and disciplines. Specialists in Arabic, Greek and Latin history of ideas, philology, palaeography and lexicography develop an intense interdisciplinary research laboratory investigating the influence of Proclus on the mutual exchanges between the scriptural monotheisms from the ninth to the sixteenth centuries. Based on fundamental archival examinations in underused library collections, NeoplAT aims (1) to identify new Arabic and Latin manuscripts and to continue to explore a corpus of texts recently discovered by the PI, representing a largely unknown intellectual heritage; (2) to retrace the scholarly networks by which Neoplatonism was transmitted between the Middle East, Byzantium and the Latin West, with particular attention to the dynamics of exchange within each cultural milieu; (3) to analyse the impact of Proclus on the history of metaphysics and on the relations between philosophy and theology within the Abrahamic traditions. NeoplAT achieves these goals through a collaborative, adapted methodology; its specific outputs will provide research tools for the broader academic community.";1992590;1992590;ERC-2017-COG;/ERC-COG;UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN;IE;OESTERREICHISCHE AKADEMIE DER WISSENSCHAFTEN;AT;;1;0;0;1;0;0 215682;798861;PeLED;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Towards Efficient and Stable Perovskite Light-Emitting Diodes;2018-07-01;2020-06-30;;"Light-emitting diodes (LEDs) based on organometallic halide perovskites have attracted increasing interest due to their unique properties, such as high colour purity, easily tunable optoelectronic properties, and solution processable for low-cost and large-arear manufacturing, showing great potential in displays and lighting applications. Even though the photonic and electronic properties of perovskites are very attractive, the poor stability and relatively low photoluminescent efficiency are two major problems that limit their progress in LEDs. In this project, I aim to address these challenges and develop efficient and stable perovskite LEDs. I propose a) to design and synthesize Ruddlesden-Popper perovskite (RPP) emitters with stable crystal structures and excellent optoelectronic properties, with the help of first-principles calculations, b) to deposit high-quality RPP films using new synthetic routes, and c) to fabricate efficient and stable LEDs with performance beyond the state of the art, by coupling device engineering with device physics investigations. This project will increase the fundamental knowledge concerning RPP materials and devices. The expected outcomes are new type perovskite materials with good optoelectronic properties, as well as stable and efficient LEDs. In addition, I will be trained to develop new interdisciplinary knowledge and skills and to reach professional maturity by implementing the project. In addition to individual development, successful implementation of this project will also promote the international competitiveness of the host organization on research of perovskite optoelectronics. Potential commercialization of the new perovskite materials and LEDs products will also generate economic growth and new job opportunities for the Europe society.";185857,2;185857,2;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;LINKOPINGS UNIVERSITET;SE;;;;1;0;0;1;0;0 215004;790491;WEAPON;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Warrior Elites: Assessing their Presence and Organisational identity in Neolithic Europe;2019-09-01;2021-08-31;;The origins of human conflict, up to and including warfare, lie not in historical documents but in the prehistoric archaeological record. While some evidence is ambiguous, injuries to the skeleton are the indisputable result of real incidents. Neolithic (6000-3000 BC) graves of the Mid-Upper Ebro and Mid-Upper Rhine valleys (northern Spain and northeastern France, respectively) contain skeletons with skeletal trauma and/or arrowhead injuries. Some of these may represent massacres involving many individuals. Moreover, emerging isotopic evidence suggests the existence of specialised warriors among them – potentially the first such in Europe. This reflects a rise in social unrest and provides an outstanding opportunity for investigating almost intangible cultural aspects. The WEAPON (Warrior Elites: Assessing their Presence and Organisational identity in Neolithic Europe) project proposes an unprecedented interdisciplinary approach to explore the identity and life-histories of those involved in the violence observed in this pivotal period. A combination of analytical methods will be used to this end, including stable carbon, nitrogen and sulphur analysis of bone collagen and tooth dentine, strontium and oxygen analysis of tooth enamel, and radiocarbon dating. The research aims to confirm the existence of ‘specialised warriors’, as well as to investigate if violence, whether regular or not, may relate to the emergence of inequalities and/or population movements across Neolithic Europe.;185076;185076;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FR;;;;1;0;0;1;0;0 215364;795569;HOPE;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;HOminin Proteomes in human Evolution;2018-11-01;2020-10-31;;This project aims to reconstruct the genetic relationships between our and extinct hominin species from sites and time periods incompatible with ancient DNA preservation through mass-spectrometry based sequencing of ancient hominin proteins. Understanding the evolutionary relationships between extinct and extant hominins is a major goal of palaeoanthropology, including insights into population dynamics and traits selected for/against in particular hominin lineages. Up to recently this was exclusively achieved through ancient DNA analysis. Ancient DNA survives for a limited amount of time, however, and is commonly degraded entirely after 0.5 or 1.0 Ma. A new biomolecular approach to this issue is the analysis of ancient proteins preserved in enamel, dentine and bone from hominin fossils, as recent studies demonstrate that ancient proteins survive for longer stretches of time than DNA. HOPE will advance these developments by applying novel methodological approaches to the extraction and characterization of hominin ancient proteins in samples beyond the survival of ancient DNA. Specific objectives are 1) to test proposed evolutionary hypotheses on hominin evolution through the characterization of ancient enamel protein sequences from a number of extinct hominin populations of significant age, 2) to increase non-collagenous protein sequence recovery from dentine samples, 3) to explore the population proteomic potential of hominin proteomes, and 4) to understand changes in enamel proteome composition throughout hominid evolution. These objectives will be realized by analysing hominin specimens from a range of taxonomic clades present in the Early, Middle and Late Pleistocene of Africa and Eurasia. HOPE thereby provides novel interdisciplinary insights into human evolution and methodological tools of use across palaeonthropology and evolutionary biology.;200194,8;200194,8;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;KOBENHAVNS UNIVERSITET;DK;;;;1;0;0;1;0;0 215464;796612;Ring-STORM;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Mechanically-Interlocked Ring-on-Thread Molecules for Super-Resolution Imaging;2018-10-15;2020-10-14;;"This interdisciplinary project focuses on the development of unprecedented autonomous novel photoactive nanoscopic molecular machines that “blink” for fluorescence microscopy imaging with a resolution higher than the light scattering limit. Its use in super-resolution imaging will represent a major innovation in imaging, both conceptually and practically, overcoming many inherent constraints associated with current techniques. By applying steady-state and time-resolved spectroscopies, photo-induced electron transfer will be used in these autonomous [2]rotaxanes to modulate fluorescence, and studies down to the single-molecule level (based on Stochastic Optical Reconstruction Microscopy) will be undertaken to achieve a new localization microscopy method ('Ring-STORM') adapted for living cells, without the need for overexpressing genetically encoded fluorescent proteins. The project will be developed at leading French research institutes, Institut des Sciences Moléculaires (ISM) and Institut d'Optique (LP2N-IOGS) both at the CNRS/Univ. Bordeaux. The fellow, a specialist in synthetic organic and supramolecular chemistry from Spain, will receive via the project training in molecular photochemistry/photophysics and super-resolution fluorescence imaging, providing him the necessary skills to design, develop and study novel tailored-made functional supramolecular architectures with enhanced spectroscopic properties. For this, the project is organized in synergistic work packages to assure efficient coordination and management, career development and training, science development, communication and technology transfer by patenting the new super-resolution imaging methodology that Ring-STORM expects to develop. This will give him independence and professional maturity towards an independent research career. The experience of the fellow, the expertise of the research groups, the infrastructure and equipment will assure the fulfilment of the project objectives.";173076;173076;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FR;;;;1;0;0;1;0;0 215099;792848;PULSATION;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Detecting and characterizing exoplanets around evolved stars with NASA's TESS mission;2018-11-01;2020-10-31;;The Transiting Exoplanet Survey Satellite (TESS) is a NASA space mission, with launch scheduled for March 2018, that will perform an all-sky survey for planets transiting bright stars. Furthermore, TESS's excellent photometric precision, combined with its fine time sampling and long intervals of uninterrupted observations, will enable asteroseismology (i.e., the study of stars by the observation of their natural, resonant oscillations). Asteroseismology is proving to be particularly significant for the study of red-giant stars, while maturing into a powerful tool whose impact is being felt across different domains of astrophysics. A noticeable example is the synergy between asteroseismology and exoplanetary science. TESS hence offers the exciting prospect of conducting asteroseismology of evolved exoplanet-host stars. The research goal of this action is to use TESS photometry to systematically detect and characterize planets transiting oscillating evolved stars. To that end, we propose an interdisciplinary research project combining transit photometry, asteroseismology and radial-velocity/spectroscopic ground-based follow-up. The proposed research project is expected to provide new insight into some of the outstanding problems in exoplanetary science, namely, on the occurrence rate of gas-giant planets as a function of stellar mass, on the correlation between stellar metallicity and giant-planet occurrence around evolved stars, and on the structural aspects of gas-giant planets. Finally, we are also committed to improving public awareness of the increasingly engaging topic of exoplanets in the host organization's home country and, as part of this action, will develop an educational/outreach program in collaboration with a non-academic partner.;160635,6;160635,6;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;CENTRO DE INVESTIGACAO EM ASTRONOMIA E ASTROFISICA DA UNIVERSIDADE DO PORTO;PT;;;;1;0;0;1;0;0 214342;792225;BIVIUM;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Standing at the Crossroads: Doubt in Early Modern Italy (1500-1560);2018-09-03;2021-09-02;;"This three-year research project aims to produce the first comprehensive social and cultural history of doubt and unbelief in Renaissance Italy. The project is timely since scholarly attention to the topic of unbelief and skepticism in Early Modern Europe is growing, as evidenced by recent publications and major research projects. In a period of dramatic cultural, political and religious change, traditional ideas and beliefs were shaken; and doubts on human reason and its powers arose. As a result, intellectual and religious authorities and long-standing truths began to be questioned by intellectuals and commoners alike, and anxiety over the powers and reach of human reason spread. A number of works were published in the vernacular that dealt with doubt and addressed a broad public. These works have never been coherently and systematically studied. This project will fill the void analysing such works with an ground-breaking interdisciplinary methodology. It will result in new comprehension of crucial aspects of European cultural identity such as the rise of the notion of freedom of conscience and the development of intellectual inquiry, and will revolutionise the traditional scholarly approach to a key moment in Italian and European civilisation. Marco Faini, an experienced researcher with international experience in Germany (Wolfenbüttel, Münster), in the UK (Cambridge), and at Villa I Tatti, is confident that the development of this project will profoundly impact his career. Thanks to the training provided by Ca’ Foscari University in Venice and by the Faculty of History at Toronto University, Faini will acquire new skills and build fruitful relations with European and North-American institutions and scholars. The training, networks and publication of the project’s outcomes will increase Faini’s possibilities of obtaining a future ERC Grant and may also result in a tenure-track position at Ca’ Foscari University.";229761;229761;H2020-MSCA-IF-2017;/MSCA-IF-GF;UNIVERSITA CA' FOSCARI VENEZIA;IT;;;;1;0;0;1;0;0 215846;801370;BP3;SIGNED;H2020-EU.1.3.4.;MSCA-COFUND-2017;H2020;Beatriu de Pinos-3 Postdoctoral Programme;2018-09-01;2023-08-31;;"The Beatriu de Pinos programme (BP) has been running successfully since 2005 and aims to promote postdoctoral research and transnational mobility in all fields of research in Catalonia. The grant will be three years long and will enable outstanding junior researchers from all nationalities to train and conduct research in any Catalan excellence research group on a project of their choice. The main objectives of the BP3 project are: a) enable the transition towards a consolidated research career attracting 120 of junior postdoctoral researchers over 5 years, multiplying each one’s skills sets and networks via targeted Career Development Plans and mentoring; b) improve the quality of postdoctoral research training; c) and increase the competitiveness of the Catalan scientific community and for extension the European one. The long term objective of BP3 is to significantly contribute to the career development of more researchers and qualified future independent leaders. The Cofund contribution will be used to add one more year to the grant, increase the number of fellowships and the líving and research and mobility allowances and provide better career opportunities and favourable working conditions in accordance with the European Charter of Researchers. Besides high level interdisciplinary scientific research training, researchers will receive additional training in complementary skills and a special personalize career development support will also be given during and after the grant finishes. Intersectoral secondments will be fostered, not only to private industry but also to the public and government sector as all of them are crucial contributors to a knowledge based society. Catalonia has fostered a successful research and knowledge hub in the south of Europe in a relatively short time and provides the postdoctoral researcher the best environment to deepen scientific skills and develop new ones. The programme is driven by AGAUR.";15717600;7858800;H2020-MSCA-COFUND-2017;/MSCA-COFUND-FP;AGENCIA DE GESTIO D'AJUTS UNIVERSITARIS I DE RECERCA;ES;;;;1;0;0;1;0;0 214444;793402;COMPRESS NETS;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Compressed Sensing Techniques for Wireless Sensor Networks;2018-09-01;2020-08-31;;The emerging Compressed Sensing theory provides an entirely new perspective on the basic principles governing data acquisition, compression, and reconstruction. The main goal of this project is to understand the fundamental design principles and investigate the ultimate capabilities of Compressed Sensing techniques in wireless sensor networks. What distinguishes this project from prior related work is that it addresses large sensor networks that rely only on wireless interconnections and are subjected to arbitrary temporal and spatial variability (caused, e.g., by channel fading, addition/removal of nodes, node mobility, etc.). We propose an optimization-based methodology which integrates compressed sensing and wireless data transport into a unified optimization framework which will serve as the mathematical basis for a systematic design and, ultimately, will reveal the performance limits. This work will provide: 1) mathematical characterizations of the optimal tradeoffs between different fundamental performance criteria (e.g., energy versus sensing accuracy), and 2) practical algorithms and hierarchically structured network protocols (i.e., key enablers for Internet of Things (IoT) applications) able of handling large amount of data with lower energy and bandwidth consumption than in existing systems. The ultimate goal is to develop the foundations for a general theory of compressive sensing in wireless sensor networks which includes all aspects mentioned above. Such theory will have a breakthrough-making impact both through direct application on the wireless sensor networks, and in the science of network and data processing in other fields, including economics, transportation, biology, etc. From a career development perspective, the main goal is to strengthen the researcher’s interdisciplinary competence and research-leadership skills for pursuing the next level of career: becoming an internationally recognized, top-tier research leader in ICT.;185857,2;185857,2;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;LINKOPINGS UNIVERSITET;SE;;;;1;0;0;1;0;0 215599;798115;TRANSURBICIDE;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Transition urbicide: Post-conflict reconstruction in post-socialist Belgrade;2018-09-01;2020-08-31;;"My project investigates manifold narratives of post-war urban transformation of cities in all the complexity of political, economic and cultural transition of post-socialist societies, taking for a test-bed the revealing case of Belgrade after the 1999 War between NATO and FR of Yugoslavia. Research on modalities and complex socio-political context in which transformation of post-war cities occur demand collection and processing of interdisciplinary sources and documents (secondary objective of my project), followed by the construction of histoire croisée of multiple actors (the primary objective) involved in reconstruction processes. Work programme is specifically tailored to achieve these goals. I will join the team of researchers at TU Delft engaged in the emerging field of documenting urban conflicts and exploring post-war urban environments. There I will use TU Delft’s web platform for spatial data collection to develop new sections of the digital archive that will contain diverse material on post-war reconstruction of Belgrade. Then I will undertake extensive training at ETH’s Institute of Digital Architectural History (secondment phase) that will help me improve on the cutting-edge tools for automatized data analysis and processing of digital architectural archives. I will then apply this knowledge to analyze collected material and develop new research protocols for architectural historiography of post-conflict cities. During the return phase at TU Delft I will transfer acquired knowledge to students and peers, refine conclusions on “transition” urbicide in Belgrade and disseminate research results. Finally, the project will offer new set of guidelines for impending urban reconstructions in active conflict zones that will shape the research of war and post-war transformation of cities in the coming years.";165598,8;165598,8;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;TECHNISCHE UNIVERSITEIT DELFT;NL;;;;1;0;0;1;0;0 215697;799017;KILNEV;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Killing Senescent Cells as a Novel Method to Eliminate Nevi;2018-04-01;2020-03-31;;"Melanoma is the most aggressive type of skin cancer, and its spread to distal tissues is often a death sentence. Immunotherapies have led to increased survival rates but they are extremely expensive and efficient for approximately only 25% of patients. Therefore research into new methods to prevent or arrest the progression of melanoma is urgently needed. Nevi are pigmented lesions on skin which consist of a clonal mass of melanocytes in a state of proliferative arrest termed ‘senescent’. This state prevents further hyperplasia, but if mutations occur in proteins required to maintain senescence, cells can re-proliferate and progress into melanoma. Selectively clearing senescent melanocytes may therefore be an effective strategy to improve current preventative measures against melanoma. This project will use a combination of interdisciplinary techniques to identify and target molecular components that confer survival to senescent melanocytes. First, I will use whole-transcriptome analysis to identify novel genes associated to cell survival. Second, genes of interest will be validated via siRNA mediated gene silencing in vitro using techniques in molecular biology to assess viability and apoptosis. Third, selected targets will be validated in vivo using a unique novel mouse model established in the host laboratory where nevi can be induced and senescent cells can be quantified by luminescence. Successful identification of these targets may lead to future development of new therapies which help reduce the health and economic impacts of malignant melanoma.";165598,8;165598,8;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;ACADEMISCH ZIEKENHUIS GRONINGEN;NL;;;;1;0;0;1;0;0 214771;776846;NEMO;SIGNED;H2020-EU.3.5.3.;SC5-14-2016-2017;H2020;Near-zero-waste recycling of low-grade sulphidic mining waste for critical-metal, mineral and construction raw-material production in a circular economy;2018-05-01;2022-04-30;;"With an estimated volume of 600 Mtonne/yr and a historic stockpile of 28,000 Mtonne, sulphidic mining waste from the production of Cu, Pb, Zn and Ni, represents the largest volume of extractive waste in Europe. When poorly managed, these “tailings” may cause major environmental problems such as acid mine drainage. In 2016 EIP Raw Materials launched a “call to arms” to transform the “extractive-waste problem” into a “resource-recovery opportunity”, as “tailings” still contain valuable & critical metals. Using a “4 PILOTS – 2 case-studies” concept NEMO develops, demonstrates and exploits, therefore, new ways to valorise sulphidic tailings. The 2 cases are the Sotkamo Ni-Cu-Zn-REE/Sc mine in Finland and the Las Cruces Cu-mine in Spain; the 4 PILOTS are located at key points in the near-zero-waste flowsheet, encompassing the recovery of valuable & critical metals, the safe concentration of hazardous elements, the removal of sulphur as sulphate salts, while using the residual mineral fraction in cement, concrete and construction products. NEMO has established an interdisciplinary consortium, including 8 industrial partners (2 mining, 4 engineering, 1 machine manufacturing & 1 construction material company), 4 research institutes, 2 universities and 1 civil society group. NEMO’s near-zero-waste technology will provide the EU with both direct and long-term, indirect advantages. The former range from new resources (e.g. base metals: Cu, Zn, Ni, Pb; critical metals: Sc, Nd, Y, Sb; SCM and aggregates etc.), CO2 savings from metal recovery and the replacement of Ordinary Portland Cement), new job creation (> 150 FTEs), new revenues (> 200 M€/yr) while the latter represent the multiplication of the former benefits (cf. 28,000 Mtonne of these tailings), while eradicating acid-mine drainage and other environmental issues, and ensuring an enhanced dialogue (framework) between industry and civil society, to obtain and maintain the License to Operate mines in EU.";14941396,5;12407294,63;H2020-SC5-2017-TwoStage;/IA;Teknologian tutkimuskeskus VTT Oy;FI;"JACOBS NV;TERRAFAME GROUP OY;VLAAMSE INSTELLING VOOR TECHNOLOGISCH ONDERZOEK N.V.;THE UNIVERSITY OF EXETER;OPTIMIZACION ORIENTADA A LA SOSTENIBILIDAD SL;RESOURCEFULL;COBRE LAS CRUCES SA;BUREAU DE RECHERCHES GEOLOGIQUES ET MINIERES;DMT GmbH & CO. KG;THYSSENKRUPP INDUSTRIAL SOLUTIONS AG;SKYSCAPE OY;COMITE ACADEMICO TECNICO DE ASESORAMIENTO A PROBLEMAS AMBIENTALES VZW;INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU METALE NEFEROASE SIRARE-IMNR;KATHOLIEKE UNIVERSITEIT LEUVEN";"BE;FI;UK;ES;FR;DE;RO";;1;0;0;1;0;0 213900;770869;CIRCOMMUNICATION;SIGNED;H2020-EU.1.1.;ERC-2017-COG;H2020;Deciphering molecular pathways of circadian clock communication;2018-03-01;2023-02-28;;"The overarching objective of this interdisciplinary project is to elucidate mechanisms through which billions of individual clocks in the body communicate with each other and tick in harmony. The mammalian circadian timing system consists of a master clock in the brain and subsidiary oscillators in almost every cell of the body. Since these clocks anticipate environmental changes and function together to orchestrate daily physiology and behavior their temporal synchronization is critical. Our recent finding that oxygen serves as a resetting cue for circadian clocks points towards the unprecedented involvement of blood gases as time signals. We will apply cutting edge continuous physiological measurements in freely moving animals, alongside biochemical/molecular biology approaches and advanced cell culture setup to determine the molecular role of oxygen, carbon dioxide and pH in circadian clock communication and function. The intricate nature of the mammalian circadian system demands the presence of communication mechanisms between clocks throughout the body at multiple levels. While previous studies primarily addressed the role of the master clock in resetting peripheral clocks, our knowledge regarding the communication among clocks between and within peripheral organs is rudimentary. We will reconstruct the mammalian circadian system from the bottom up, sequentially restoring clocks in peripheral tissues of a non-rhythmic animal to (i) obtain a system-view of the peripheral circadian communication network; and (ii) study novel tissue-derived circadian communication mechanisms. This integrative proposal addresses fundamental aspects of circadian biology. It is expected to unravel the circadian communication network and shed light on how billions of clocks in the body function in unison. Its impact extends beyond circadian rhythms and bears great potential for research on communication between cells/tissues in various fields of biology.";1999945;1999945;ERC-2017-COG;/ERC-COG;WEIZMANN INSTITUTE OF SCIENCE;IL;;;;1;0;0;1;0;0 213917;772676;QUEM-CHEM;SIGNED;H2020-EU.1.1.;ERC-2017-COG;H2020;Time- and space- resolved ultrafast dynamics in molecular-plasmonic hybrid systems;2018-05-01;2023-04-30;;"This project aims at developing theoretical and numerical methods to simulate space- and time-resolved ultrafast dynamics in novel hybrid molecular-metal nanoparticle systems. The excitation of collective electron dynamics inside the metallic nanoparticles induced by external light fields leads to strongly re-shaped electromagnetic near-fields with complex spatial and temporal profile. The interaction of these modified and enhanced near-fields with molecules located in close vicinity to the metallic nanoparticle is the origin of many astonishing physical and chemical phenomena, such as the formation of new quasi-particles, new mechanisms for chemical reactions or the ultra-high spatial resolution and selectivity in molecular detection.. Besides being of fundamental interest, this interplay between near-fields and molecules promises great potential on the application side, potentially enabling revolutionary breakthrough in new emerging technologies in a broad range of research fields, such as nanophotonics, energy and environmental research, biophotonics, light-harvesting energy sources, highly sensitive nano-sensors etc. This necessitates a solid theoretical understanding and simulation of these hybrid systems. The goal of project QUEM-CHEM is the development of new approaches and methods beyond the state of the art, aiming at a synergy of existing but independently applied methods: • Quantum chemistry (QU) in order to calculate the quantum nature of the molecule-metallic nanoparticle moiety, • Electro-dynamic simulations (EM) describing the complex evolution of the light fields and the near fields around nanostructures, as well as • Dynamical methods to incorporate the response of the molecule to the near-fields Thus, the possible outcome of this highly interdisciplinary project will provide new knowledge in both, physics and chemistry, and might have impact on a large variety of new arising critical technologies.";1901400;1901400;ERC-2017-COG;/ERC-COG;Friedrich Schiller University Jena;DE;;;;1;0;0;1;0;0 214159;795393;PhiloMagic;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;The Art of the Impossible: A Philosophical Study of Theatrical Magic;2019-08-01;2021-07-31;;PhiloMagic is an interdisciplinary project in philosophical aesthetics in the analytic tradition. It focuses primarily on the art of theatrical magic (think David Copperfield, not Harry Potter), which the American Society for Aesthetics recognizes as a “neglected art.” PhiloMagic builds on my prize-winning essay, “The Experience of Magic,” which is the first systematic philosophical treatment of theatrical magic in the analytic—or, to my knowledge, any—tradition. For my fellowship, I propose a 24-month stay at the Centre for Philosophical Psychology at the University of Antwerp under the supervision of Professor Bence Nanay. While in Antwerp, my main objectives are to complete a book manuscript (entitled *The Art of the Impossible*), write and submit for publication three accompanying scholarly articles, and organize a series of four study groups (each culminating in a public lecture) as well as an international workshop in the philosophy and psychology of magic.;172800;172800;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;UNIVERSITEIT ANTWERPEN;BE;;;;1;0;0;1;0;0 213842;797242;SPotEU;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Sugar Pot manufacture in western Europe in the medieval and post-medieval period (11th-16th centuries AD);2018-10-01;2020-09-30;;The SPotEU project explores the development and impact of sugar production in western Europe through the study of sugar pot manufacture from an interdisciplinary perspective, integrating archaeological and historical research with material science and material culture approaches in an innovative way. Sugar production and consumption followed the Islamic expansion in the western Mediterranean and had a huge impact on European social, cultural and economic development since medieval times. The introduction of sugar cultivation entailed knowledge transfer and new technological requirements, such as the manufacture of sugar pots, used for the crystallization of the sugar, which require specific design, thermal and mechanical properties. The project focuses on Sicily and Spain, the two main regions for sugar production in western Europe in the 11th-16th centuries AD. Sugar pots from these regions will be assessed on a morphological, technological and performance point of view aided by instrumental analysis (Petrography, SEM, XRF, XRD, porosity, mechanical and thermal stress test) and software modelling (FEM). The comparison with reference ceramic materials and written records will allow the investigation of the scale of ceramic production and exchange networks, as well as potters’ technological choices in the construction of these on-purpose vessels. For the first time, sugar pots from western Europe will be examined in such technological detail that will allow the assessment of the way in which the performance of vessel was influenced by technological choices and by design, giving new insights on knowledge transfer and technological innovation across the Mediterranean in late medieval and post-medieval times. In contrast to previous studies based on written sources, this project uses a bottom-up approach and it will shed light on the role of craftspeople in the development of the first industrial activity in modern Europe by a detailed technological analysis of sugar pots.;170121,6;170121,6;H2020-MSCA-IF-2017;/MSCA-IF-EF-CAR;UNIVERSITAT DE BARCELONA;ES;;;;1;0;0;1;0;0 213485;772070;ASA;SIGNED;H2020-EU.1.1.;ERC-2017-COG;H2020;Understanding Statehood through Architecture: a comparative study of Africa's state buildings;2018-09-01;2023-08-31;;"The project will develop a new ethnography of statehood through architecture. It goes beyond conventional approaches to statehood, which describe states as an objectively existing set of tools used to run a country, and critical approaches that understand them as discursive constructs. Instead, this research understands statehood as a result of the relationship between functions and symbols, and will read it through an innovative new methodology, namely a study of state architecture. The study will focus on state buildings in Africa. African statehood, uncertain and often ambiguous, in many cases profoundly shaped by colonial heritages and post-colonial relationships, is reflected in classical-colonial, modernist-nationalist and post-modern or vernacular styles of architecture. African state buildings reveal the complex interplay of ideas, activities and relationships that together constitute an often uncomfortable statehood. They symbolise the state, embodying and projecting ideas of it through their aesthetics; they enable its concrete functions and processes; and they reveal what citizens think about the state in the ways they describe and negotiate them. The study is comparative, multi-layered and interdisciplinary. It focuses on seven countries (South Africa, Tanzania, DR Congo, Ethiopia, Ghana, Côte d’Ivoire and Guinea Bissau), exploring politics and statehood on domestic, regional and international levels, and drawing on theory and methods from political science, history, sociology, art and architecture theory. It employs innovative ethnographic methods, including the collection and display of photographs in interactive exhibitions staged in Africa to explore the ways citizens think about and use state buildings. This project will provide an innovative reading of how African statehood is expressed and how it looks and feels to African citizens. In doing this, it will make a distinctive new contribution to understanding how statehood works everywhere.";1870665;1870665;ERC-2017-COG;/ERC-COG;ROYAL HOLLOWAY AND BEDFORD NEW COLLEGE;UK;;;;1;0;0;1;0;0 213948;787344;WAVREP;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;WAVe Resource for Electrical Production;2018-05-01;2020-04-30;;WAVREP aims to challenge the notion that wave energy should be considered only at energetic regions exposed to open ocean waters. More than 70% of EU coastlines have moderate wave energy resource of 3000-6000 W/m at deployment depths resulting in lower harsh conditions when compared to open ocean coasts. Most Wave Energy Converters (WECs) are developed for higher operational ranges (ocean coasts), with WEC capacity factors and availability at such areas not exceeding 15% and 40% respectively. Higher latitude regions encompass larger wave environments that can propagate high energy content from 5000-8000 W/m. However, such conditions impose significant stresses on the structural integrity and negatively affect expected energy production of WECs, with final capacity factors not exceeding 15-25% (device dependent). WECs at highly energetic wave environment also require higher survivability considerations and have reduced maintenance times. Such factors result at higher capital, operational and energy costs, hindering WECs cost-effectiveness. Using an interdisciplinary scientific methodology the project aims to provide a WEC that can attain higher availability and capacity factors over 60% and 30% respectively, enhancing its global applicability.;165598,8;165598,8;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;TECHNISCHE UNIVERSITEIT DELFT;NL;;;;1;0;0;1;0;0 213407;759880;Damocles;SIGNED;H2020-EU.1.1.;ERC-2017-STG;H2020;Modelling brain aneurysm to elucidate the role of platelets;2018-06-01;2023-05-31;;"In the European Union, 15 million people have an unruptured intracranial aneurysm (IA) that may rupture one day and lead to subarachnoid haemorrhage (SAH). The IA rupture event is ominous and lingers as a clinical quandary. No safe and effective non-invasive therapies have, as of yet, been identified and implemented in clinical practice mainly because of a lack of knowledge of the underlying mechanisms. Increasing evidence points to inflammation as one of the leading factors in the pathogenesis of IA. Intrasaccular clot formation is a common feature of IA occurring unruptured and ruptured IA. In addition to forming clots, activated platelets support leukocyte recruitment. Interestingly, platelets also prevent local hemorrhage in inflammatory situations independently of their ability to form a platelet plug. We hypothesize that the role of platelet may evolve throughout the development of IA: initially playing a protective role of in the maintenance of vascular integrity in response to inflammation and contributing later to intrasaccular thrombus formation. What are the platelet signaling pathways and responses involved and to what extent do they contribute to the disease and the rupture event? To answer these questions, we designed an interdisciplinary proposal, which gathers biophysical, pharmacological, and in-vivo approaches, with the following objectives: I) To investigate platelet functions from patients diagnosed with intracranial aneurysm at the sites of aneurysm sac. II) To delineate platelet mechanisms and responses in a cutting-edge technology of a 3D reconstruction of IA that will take into account the hemodynamic shear stress. III) To test in a preclinical mouse model of IA efficient anti-platelet therapies and define a therapeutic window to intervene on platelet activation. The proposed project will yield new insights in IA disease and in life science, from cell biology to the discovery of potential new targets in cardiovascular medicine.";1498618;1498618;ERC-2017-STG;/ERC-STG;INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE;FR;;;;1;0;0;1;0;0 213961;793135;DeepRNA;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Discovering functional protein-RNA interactions through data integration and machine learning.;2018-03-01;2020-02-29;;"RNA-binding proteins are implicated across a wide spectrum of human genetic disorders, with molecular mechanisms ranging from aggregation of proteins and RNAs to defects in splicing and translation. Examples include heterogeneous and life-threatening genetic disorders such as Diamond-Blackfan anaemia, spinocerebellar ataxia and amyotrophic lateral sclerosis (ALS) among others. The DeepRNA project targets genetic diseases via disease-associated variants in the human transcriptome and is enabled by recent data on expression quantitative trait loci (eQTLs) and experimentally determined RNA-protein and RNA-RNA interactions. The data will be complemented with high-quality RNA-protein interaction predictions carried out in the host group that has a strong track record in computing and validating RNA-protein associations. To my knowledge the use of eQTL variants to study RNA-protein interactions is a novel approach and is useful for developing new tools for personalised medicine. My approach will expand the human interactome in a genome-wide manner beyond experimental data, which is currently available for only 352 of the 1,542 recently described RNA-binding proteins. Complementing experimentally determined interactions with predictions will allow me to expand my analyses of the human interactome to the genomic scale while maintaining accuracy, by using the experimental dataset as a gold standard. I will employ methods such as graph partitioning and graph neural network encoding to rationalise the effects of disease-associated variants on the human interaction network, and make quantitative predictions of polymorphisms associated with genetic diseases, thereby aiding personalised medicine. I am confident that this fellowship will equip me with the domain knowledge, independence and transferrable skills to confidently and creatively build an interdisciplinary, globally recognised research team within Europe that will focus on medically relevant human signalling systems.";158121,6;158121,6;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;FUNDACIO CENTRE DE REGULACIO GENOMICA;ES;;;;1;0;0;1;0;0 213952;789865;EnSurf;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Enantioselectivity at surfaces: covalent grafting as new tool for chiral surface modifications;2018-03-01;2020-02-29;;"Chiral surfaces have received considerable attention in the recent past since they play an important role as substrates for chiral separations and enantioselective heterogeneous catalysis. One of the most frequently used approaches to design and fabricate chiral surfaces is the adsorption and self-assembly of chiral or prochiral molecules on surfaces, which can be studied with sub-molecular resolution by scanning tunneling microscopy (STM). Thereby, the fabrication of homochiral surfaces is of particular interest. However, a major drawback of this approach is, in particular in view of potential applications, the lack of stability of physisorbed molecules. Therefore, EnSurf aims to use covalent surface modifications as chiral surface modifiers and new experimental approach for the creation of homochirality and enantioselectivity in self-assembling molecular structures at the solid/liquid interface. This interdisciplinary project takes place in the field of surface and interface science and involves aspects of supramolecular chemistry, synthetic chemistry, analytical chemistry and theoretical chemistry. Ultimately, this project will allow the fellow to attain professional independence and a position at the frontier of future academic or industrial research by a combination of hands-on experience in diverse research areas and training in complementary skills.";160800;160800;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;KATHOLIEKE UNIVERSITEIT LEUVEN;BE;;;;1;0;0;1;0;0 214047;757247;DATAJUSTICE;SIGNED;H2020-EU.1.1.;ERC-2017-STG;H2020;Global data justice in the era of big data: toward an inclusive framing of informational rights and freedoms;2018-03-01;2023-02-28;;"The increasing adoption of digital technologies worldwide creates data flows from places and populations that were previously digitally invisible. The resulting ‘data revolution’ is hailed as a transformative tool for human and economic development. Yet the revolution is primarily a technical one: the power to monitor, sort and intervene is not yet connected to a social justice agenda, nor have the organisations involved addressed the discriminatory potential of data technologies. Instead, the assumption is that the power to visualise and monitor will inevitably benefit the poor and marginalised. This research proposes that a conceptualisation of data justice is necessary to determine ethical paths through a datafying world. Its two main aims are: first, to provide the first critical assessment of the case for, and the obstacles to, data justice as an overall framework for data technologies’ design and governance. Second, to present a conceptual framework for data justice, refining it through public debate. The project will develop an interdisciplinary approach integrating critical data studies with development studies and legal philosophy. Using Sen's Capabilities Approach, it will conceptualise data justice along three dimensions of freedoms: (in)visibility, digital (dis)engagement, and nondiscrimination. Multi-sited ethnography in combination with digital methods will be used to build a conceptual framework, which will then be tested and shaped by debates held in nine locations worldwide. The research is groundbreaking in terms of 1) its use of the Capabilities Approach to address the social impacts of data technologies; 2) its integrative approach to problems previously addressed by the fields of law, informatics and development studies, and 3) its aim to reconcile negative with positive technologically-enabled freedoms, integrating data privacy, nondiscrimination and non-use of data technologies into the same framework as representation and access to data.";1495986;1495986;ERC-2017-STG;/ERC-STG;STICHTING KATHOLIEKE UNIVERSITEIT BRABANT;NL;;;;1;0;0;1;0;0 213392;757913;NovAnI;SIGNED;H2020-EU.1.1.;ERC-2017-STG;H2020;Indentification and optimisation of novel anti-infective agents using multiple hit-identification strategies;2018-02-01;2023-01-31;;"Given the rapid emergence of anti-infective resistance, drugs with a novel mode of action are urgently needed. Because of an exhaustion of existing strategies, a low return on investment and the fact that anti-infectives are difficult to develop (e.g., crossing the peculiar cell wall of Mycobacterium tuberculosis), promising un(der)explored targets and unconventional hit-identification strategies are needed. I have selected three anti-infective targets based on their biochemical context for which few or no small-molecule inhibitors are known: 1) The antimalarial and antituberculotic drug target DXS is part of a unique biosynthetic pathway for pathogens that is absent in humans, thereby circumventing selectivity issues. Both diseases are a serious health threat with around 1.9 million deaths per year. 2) Energy-coupling factor transporters are essential vitamin importers for pathogens such as Staphylococcus aureus, the causative agent of methicillin-resistant Staphylococcus aureus (MRSA) infections. 3) The DNA polymerase sliding clamp DnaN has polymerase and DNA repair activities and is an excellent drug target for the development of antibacterial agents against Gram-negative and –positive bacteria given the low incidence of resistance development. I will address these targets, employing a unique combination of potentially synergistic hit-identification strategies that take into account protein flexibility, provide access to novel scaffolds and give me a cutting edge for the development of novel anti-infectives. This ERC proposal builds on my experience with the first two targets and provides an excellent platform for the new target DnaN. My expertise in synthetic organic and medicinal chemistry and established hit-identification strategies together with my collaborations with protein crystallographers, biochemists and pharmacologists place me in an excellent position for not only achieving the goals of this interdisciplinary proposal but also going beyond it.";1499367;1499367;ERC-2017-STG;/ERC-STG;HELMHOLTZ-ZENTRUM FUER INFEKTIONSFORSCHUNG GMBH;DE;;;;1;0;0;1;0;0 213374;701561;ASUNDER;TERMINATED;H2020-EU.1.3.2.;MSCA-IF-2015-GF;H2020;Environmental subjects, conflicts and commodity frontiers;;;;The fellowship aims at establishing the applicant an expert in the study of environmental conflicts through training in the interdisciplinary fields of political ecology and environmental history at the University of Wisconsin-Madison (UW). Training will consist in courses on environmental history at the Centre for Culture, History & Environment and research under the guidance of the Nelson Institute for Environmental Studies Director Prof Paul Robbins. The research project will mobilise political ecology theory on environmental subjects and environmental history research methods to investigate the understudied phenomenon of acceptance of environmental harm occurring in the course of environmental conflicts. This will be examined through a case study of a conflict over silica sand mining – an activity necessary to obtain sand for use in the controversial process of shale gas extraction (fracking) – in Wisconsin, the larger silica producer in the US. The project will advance theory and analysis of ecological distribution conflicts. The fellow will benefit from interactions with UW’s Geography department political ecology experts and complementary skills training in science communication via digital media technologies (podcasts) and radio. The fellow will expand his network and expertise by attending specialised seminars and benefit from UW’s world-class library facilities. Project findings will be integrated in European research networks working on environmental conflicts, ecological economics and political ecology and contribute to making the European Research Area a centre of excellence in those fields. Knowledge from the outgoing period will be reintegrated in the Institute of Environmental Science & Technology of Universitat Aut?noma de Barcelona through postgraduate teaching and supervision, and by establishing a distinctive line of research on subjects and environmental conflict. Long-term collaboration between host institutions is envisaged through the project.;257191,2;257191,2;H2020-MSCA-IF-2015;/MSCA-IF-GF;UNIVERSITAT AUTONOMA DE BARCELONA;ES;;;;1;0;0;1;0;0 213992;796762;BiomCatOx;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Biomimetic Dicopper Architecture for Catalytic Oxygen Activation;2018-03-01;2020-02-29;;BiomCatOx will explore a unique catalyst design for the valorisation of hydrocarbons by oxygen insertion into a C–H bond under mild reaction conditions and using O2 as cheap and benign oxidant. The key concept of BiomCatOx is to rigorously control the activation of O2 and the formation of metal-based reactive oxygen species (ROS) to accomplish selective and catalytic oxidation of hydrocarbons. The novelty of BiomCatOx lies in the design of the catalyst that consists in connecting a heavily truncated protein as electron relay for controllable intramolecular electron transfer (IET) to a synthetic oxidation catalyst. The intramolecular electron transfer can be rationally custom-tailored and therefore provides strict control on the reactivity of the catalytic center and on the formation of the ROS. BiomCatOx will use a stepwise approach involving (i) the development of copper-NHC complexes as powerful catalysts for the formation of ROS and hydrocarbon oxidation, (ii) the development of a copper peptide derived from the azurin active site for efficient electron transfer, and (iii) the covalent connection of the two copper sites into a peptide-complex dicopper conjugate for controlled intramolecular electron transfer. The implementation of BiomCatOx will provide efficient catalytic systems and fundamental insights into electron transfer, and discloses a new catalyst design concept. BiomCatOx is highly interdisciplinary and merges organometallic chemistry, homogeneous catalysis, enzymology, and spectroscopy. This training at the University of Bern (CH) and of Nottingham (UK, secondment) will convey a unique skill set. Together with the personalized career development plan, I will gain significant scientific and soft skills to boost my career and to become an internationally recognized academic leader in Europe at the bioinorganic chemistry/catalysis interface. Communication and management trainings will increase my competence and strongly support my career perspectives.;175419,6;175419,6;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;UNIVERSITAET BERN;CH;;;;1;0;0;1;0;0 214212;799291;MappingSpatialVision;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Linking the perceptual and neural mechanisms of human spatial perception using behavioral and ultra-high field fMRI signals;2019-06-01;2021-05-31;;The present research aims to further our understanding of the mechanisms by which our brain makes sense of the visual world. Our brain cannot represent with full fidelity the overwhelming amount of information it constantly faces. Yet, understanding our visual world seems effortless. One strategy developed by the brain is to trade off poor spatial representations in the periphery for high-resolution foveal vision. Spatial attention is another strategy the brain relies on to select and prioritize visual processing at relevant areas of the visual field without having to move our eyes. Perceptually, attention benefits performance in many visual tasks, in line with heightened spatial resolution at the attended area. Physiologically, single-neuron recordings in animals have shown that attention alters the receptive-field (RF) properties of neurons, which may account for changes in human perception. Yet, human behavior depends on large-scale neuronal population codes. Thus, understanding how attention helps us represent information across the visual field requires to link human perception with changes in human neuronal populations. Here, I will do exactly that by combining a powerful behavioral approach I developed with recent neuroimaging techniques that can assess human neuronal population RF properties. Using cutting-edge, ultra-high resolution neuroimaging methods, I will pinpoint the neural mechanisms by which attention alters spatial representations at unprecedented levels of cortical organization in the human brain, further establishing the host’s recognition as a world-leading brain research center. This interdisciplinary training will reinforce my previous research skills and provide me with state-of-the-art neuroimaging expertise. The MSCA fellowship is a unique chance to expand my skills and reintegrate the European research community, putting me on the right track to pursue an independent career with a multifaceted profile of psychologist and neuroscientist.;177598,8;177598,8;H2020-MSCA-IF-2017;/MSCA-IF-EF-RI;KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW;NL;;;;1;0;0;1;0;0 214116;792932;DIPLOWAR;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Hybrid Practices of Diplomacy and Warfare;2018-09-01;2020-08-31;;DIPLOWAR is an interdisciplinary research project that uses practice theory to illuminate the changing relationship between diplomacy and warfare. The central conceptual move of the project is to conceive of diplomacy and warfare not primarily as political or legal relations between states but as structuring principles of peaceful and violent political practices. This reconceptualization allows integrating insights from the literatures on the ‘new diplomacy’ and the ‘new wars’ which so far have not been brought into a dialogue. Through an explorative study of foreign policy decision-making in the United States and Germany from 1945 to the present, the project will demonstrate that practices of diplomacy and warfare which once were neatly separated have increasingly formed hybrid constellations. As a result, we are today confronted with a situation in which neither diplomacy nor war can be clearly grasped at the level of inter-state relations anymore. DIPLOWAR seeks to both sharpen our analytical vocabulary and deepen our empirical understanding of these processes of hybridisation to help scholars, practitioners, and the public to come to terms with the new realities of war and peace. The outgoing phase of the project will be hosted by the Arnold A. Saltzman Institute for War and Peace Studies at Columbia University, New York, the return phase by the Faculty of Social Sciences at Goethe University Frankfurt.;159795,6;159795,6;H2020-MSCA-IF-2017;/MSCA-IF-GF;JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN;DE;;;;1;0;0;1;0;0 214156;795179;CROSSGRASS;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Cross-border analysis of grassland greenness in Asia: Climate variations, grazing pressure, and land policy change;2018-04-01;2020-03-31;;The Asian grasslands that stretch from the Eastern shores of the Caspian Sea to Manchuria in China are the largest continuous grassland biome worldwide and play a vital role in global carbon sequestration and in sustaining biodiversity. In recent decades, the integrity of the Asian grasslands became threatened by climate change and increasing land-use intensity, which in turn jeopardize the livelihoods of millions of residents that rely on the grassland resources for feeding their animals. To date, however, the spatial and temporal patterns of the changes in grassland resources across the region have not been systematically assessed. Moreover, it remains elusive how changing grazing intensity, climate variations, and institutional transformations have affected the grassland dynamics. This project aims to fill this gap by mapping the spatial patterns of vegetation changes across the Asian grassland biome for the past three and a half decades, and by quantifying the drivers of these changes. The dynamics of grassland greenness, as a proxy of plant growth, will be assessed using vegetation indices derived from remote sensing data. The changes in grassland greenness will then be statistically associated with climate data, subnational livestock statistics, and other control variables using spatial econometric panel analysis at fine spatial grain and annual temporal resolution. Combined, these analyses will shed light on the importance of climate variations and land-use intensity across institutional boundaries. Such insights are pertinent for deriving management options and policy solutions that simultaneously reduce grassland degradation and secure rural livelihoods in Asia. Besides the scientific goals, this action will provide a platform for the applicant and the host to share and transfer their knowledge and experiences in interdisciplinary research in human-environmental systems.;159460,8;159460,8;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;LEIBNIZ-INSTITUT FUER AGRARENTWICKLUNG IN TRANSFORMATIONSOEKONOMIEN (IAMO);DE;;;;1;0;0;1;0;0 212747;758329;AGEnTh;SIGNED;H2020-EU.1.1.;ERC-2017-STG;H2020;Atomic Gauge and Entanglement Theories;2018-05-01;2023-04-30;;"AGEnTh is an interdisciplinary proposal which aims at theoretically investigating atomic many-body systems (cold atoms and trapped ions) in close connection to concepts from quantum information, condensed matter, and high energy physics. The main goals of this programme are to: I) Find to scalable schemes for the measurements of entanglement properties, and in particular entanglement spectra, by proposing a shifting paradigm to access entanglement focused on entanglement Hamiltonians and field theories instead of probing density matrices; II) Show how atomic gauge theories (including dynamical gauge fields) are ideal candidates for the realization of long-sought, highly-entangled states of matter, in particular topological superconductors supporting parafermion edge modes, and novel classes of quantum spin liquids emerging from clustering; III) Develop new implementation strategies for the realization of gauge symmetries of paramount importance, such as discrete and SU(N)xSU(2)xU(1) groups, and establish a theoretical framework for the understanding of atomic physics experiments within the light-from-chaos scenario pioneered in particle physics. These objectives are at the cutting-edge of fundamental science, and represent a coherent effort aimed at underpinning unprecedented regimes of strongly interacting quantum matter by addressing the basic aspects of probing, many-body physics, and implementations. The results are expected to (i) build up and establish qualitatively new synergies between the aforementioned communities, and (ii) stimulate an intense theoretical and experimental activity focused on both entanglement and atomic gauge theories. In order to achieve those, AGEnTh builds: (1) on my background working at the interface between atomic physics and quantum optics from one side, and many-body theory on the other, and (2) on exploratory studies which I carried out to mitigate the conceptual risks associated with its high-risk/high-gain goals.";1055317;1055317;ERC-2017-STG;/ERC-STG;SCUOLA INTERNAZIONALE SUPERIORE DI STUDI AVANZATI DI TRIESTE;IT;;;;1;0;0;1;0;0 213156;780529;Easy Reading;SIGNED;H2020-EU.2.1.1.;ICT-23-2017;H2020;Easy Reading: A Framework for Personalised Cognitive Accessibility when using Original Digital Content;2018-01-01;2020-06-30;;"The “Easy Reading” framework will improve the cognitive accessibility of original digital documents by providing real time personalisation through annotation (using e.g. symbol, pictures, videos), adaptation (using e.g. layout, structure) and translation (using e.g Easy-to-Read, Plain Language, symbol writing systems). The framework provides these (semi-)automated services using HCI techniques (e.g. pop-ups/ Text-To-Speech (TTS)/captions through mouse-over or eye-tracking) allowing the user to remain and work within the original digital document. This fosters independent access and keeps the user in the inclusive discourse about the original content. Services adapt to each user through a personal profile (sensor based tracking and reasoning of e.g. the level of performance, understanding, preferences, mood, attention, context and the individual learning curve). The interdisciplinary project team includes users with cognitive disabilities in all phases through the Inclusive Participatory Action Research Method (IPAR) ensuring to address real users´ needs. The “Easy Reading” framework is planned as a cloud based, open source and freely available support infrastructure. It will reach as many people with limited reading and language skills (e.g. people with cognitive disabilities - ~2,5% of the population - older adults, people with a different mother tongue) summing up to 25% in some regions or countries. Additionally, many more people will enjoy exploring new and unfamiliar content using personalised access. This framework integrates and supports state-of-the-art and future R&D. It incorporates tools for annotation, adaptation and translation of content by providing a sustainable user-centred eco-system for personalisation. It promotes European ideals and enables independent applications to leverage the infrastructure and socialize their application for business (profit and non-for profit) in a new EU driven growth market.";2237875;1992063;H2020-ICT-2017-1;/RIA;UNIVERSITAT LINZ;AT;"KOMPETENZNETZWERK INFORMATIONSTECHNOLOGIE ZUR FOERDERUNG DER INTEGRATION VON MENSCHEN MIT BEHINDERUNGEN;ATHENA I.C.T. LTD;FUNKA NU AB;IN DER GEMEINDE LEBEN GGMBH - HILFEN FUR MENSCHEN MIT BEHINDERUNGEN;TECHNISCHE UNIVERSITAT DORTMUND;TEXTHELP LTD;VASTRA GOTALANDS LANS LANDSTING;GEIE ERCIM";"AT;IL;SE;DE;UK;FR";;1;0;0;1;0;0 212726;757848;CoQuake;SIGNED;H2020-EU.1.1.;ERC-2017-STG;H2020;Controlling earthQuakes;2018-06-01;2023-05-31;;According to the Centre for Research on the Epidemiology of Disasters (CRED), earthquakes are responsible for more than half of the total human losses due to natural disasters from 1994 to 2003. There is no doubt that earthquakes are lethal and costly. CoQuake proposes an alternative, ground-breaking approach for avoiding catastrophic earthquakes by inducing them at a lower energetic level. Earthquakes are a natural phenomenon that we cannot avoid, but –for the first time– in CoQuake I will show that it is possible to control them, hence reducing the seismic risk, fatalities and economic cost. CoQuake goes beyond the state-of-the-art by proposing an innovative methodology for investigating the effect and the controllability of various stimulating techniques that can reactivate seismic faults. It involves large-scale, accurate simulations of fault systems based on constitutive laws derived from micromechanical, grain-by-grain simulations under Thermo-Hydro-Chemo-Mechanical couplings (THMC), which are not calibrated on the basis of ad-hoc empirical and inaccurate constitutive laws. A pioneer experimental research programme and the design and construction of a new apparatus of metric scale, will demonstrate CoQuake’s proof-of-principle and it will help to explore the transition from aseismic to seismic slip. CoQuake is an interdisciplinary project as it takes knowledge from various fields of engineering, computational mechanics, geomechanics, mathematics and geophysics. CoQuake opens a new field and new line of research in earthquake mechanics and engineering, with a direct impact on humanity and science.;1499999;1499999;ERC-2017-STG;/ERC-STG;ECOLE NATIONALE DES PONTS ET CHAUSSEES;FR;;;;1;0;0;1;0;0 213018;778263;AlgaeCeuticals;SIGNED;H2020-EU.1.3.3.;MSCA-RISE-2017;H2020;Development of microalgae-based natural UV Sunscreens and Proteins as cosmeceuticals and nutraceuticals;2018-01-01;2021-12-31;;The biotechnology of microalgae has gained considerable importance in recent decades, as they represent a largely untapped reservoir of novel and valuable bioactive compounds. The biological and chemical diversity of the microalgae, has been the source of unique bioactive molecules with the potential for industrial development as pharmaceuticals, cosmetics, nutritional supplements. The proposed project will combine both basic and applied research in the fields of –omics technologies, biochemistry, applied and enzyme biotechnology in order to exploit microalgae resources for the development: 1) Natural UV sunscreens, based on algae mycosporine-like aminoacids, 2) Algae-based nutraceuticals as functional foods and food supplements, 3) Algae-derived proteases with applications in cosmetic (skin repair enzymes) and food industry. The implementation of the project will offer to the involved academic and SMSs the opportunity to translate scientific research into well defined knowledge-based ‘green’ products and analytical tools. Apart from scientific objectives, the project will enhance the European’s capacity in the field of Blue Growth and Marine Biotechnology by exchanging interdisciplinary knowledge, developing and disseminating joint research activities, thus strengthening the intersectoral links between academia and industry for sustainable growth.;1129500;1129500;H2020-MSCA-RISE-2017;/MSCA-RISE;ETHNIKO KENTRO EREVNAS KAI TECHNOLOGIKIS ANAPTYXIS;EL;"IGV GREENFOOD GGMBH;EPARELLA GMBH;BIONOS BIOTECH SL;AGRICULTURAL UNIVERSITY OF ATHENS;ASOCIACION EMPRESARIAL DE INVESTIGACION CENTRO TECNOLOGICO NACIONAL DE LA CONSERVA;FONDAZIONE EDMUND MACH;FRESH FORMULA PRIVATE LIMITED COSMETICS MANUFACTURING COMPANY";"DE;AT;ES;EL;IT";;1;0;0;1;0;0 212670;754702;ME-WE;SIGNED;H2020-EU.3.1.2.;SC1-PM-07-2017;H2020;Psychosocial Support for Promoting Mental Health and Well-being among Adolescent Young Carers in Europe;2018-01-01;2021-03-31;;"Adolescent young carers (AYCs) are young people (15-17 years old) providing significant or substantial care, assistance or support to other family members. The phenomenon is highly relevant across Europe, albeit specific data, awareness and supports are not frequently available. Taking on a caring role constitutes a relevant risk factor for the occurrence of both immediate and long-term problems in AYCs’ mental health, well-being and development, as well as for their transitions to adulthood, social inclusion, education and employability. The goal of the project is to strengthen the resilience of AYCs, improve their mental health and well-being, and mitigate the negative influences of psychosocial and environmental factors. The project develops an innovative framework of primary prevention interventions to be tested and adapted in six European countries (Italy, Netherlands, Slovenia, Sweden, Switzerland, United Kingdom) at different stages of awareness and development of services for AYCs. The project has three specific objectives: (1) to systematise knowledge on AYCs; (2) to co-design, test and deliver psychosocial interventions in six countries; (3) to evaluate what works and provide knowledge translation actions at national, European and international levels. The project adopts an interdisciplinary approach by complementing expertise and longstanding experience of partners. The consortium includes Eurocarers members, research and carers organisations, working together with and for AYCs. AYCs will be continuously involved in the project – together with other stakeholders – via national Blended Learning Networks, user groups, workshops, and in an International Advisory and Ethics Board. The project will have international impact, improving AYCs’ mental health and well-being, educational outcomes, transition, employability and social inclusion, as well as creating evidence-based practices, to improve health equity and societal benefits.";3999885;3999885;H2020-SC1-2017-Two-Stage-RTD;/RIA;LINNEUNIVERSITETET;SE;"EUROCARERS-ASSOCIATION EUROPEENNE TRAVAILLANT AVEC ET POUR LES AIDANTS NON-PROFESSIONNELS;STICHTING VILANS;CARERS TRUST;ANZIANI E NON SOLO SOCIETA COOPERATIVA SOCIALE;MINISTERIE VAN VOLKSGEZONDHEID, WELZIJN EN SPORT;STIFTUNG KALAIDOS FACHHOCHSCHULE;THE UNIVERSITY OF SUSSEX;ISTITUTO NAZIONALE DI RIPOSO E CURA PER ANZIANI INRCA;UNIVERZA V LJUBLJANI";"BE;NL;UK;IT;CH;SI";;1;0;0;1;0;0 212637;749699;WACO;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;West African Coastal Ocean - Finescale physics, biogeochemistry and climate change;2018-03-01;2020-02-29;;Coastal oceans are essential to our societies but their health status is degrading rapidly in many parts of the world. Anticipating or remedying environmental evolutions/degradations, including those resulting from global changes, is particularly difficult. This is largely because the knowledge and information we currently have on the ocean functioning do not encompass scales finer than a few tens of kilometers, which is notably insufficient close to shores. WACO will clarify the role of fine-scale processes (turbulent and wave processes with scales < 10 km) in the present-day functioning and future evolutions of the West African coastal dynamics and biogeochemistry. To do so, it will take advantage of a new generation of ocean models that is truly apt to simulate coastal dynamics/biogeochemistry/ecosystems in a fully integrated and multi-scale manner. Precisely, the project will be focused on the senegalese and mauritanian coastal oceans from which state-of-the-art ocean observations are available to complement and evaluate the modelling effort, a robust and interdisciplinary collaborative framework, and unmatched opportunities for social benefits of the research. The project relies on a massively parallel computing plan that will serve as a demanding training ground for the applicant. Overall WACO will contribute to a deeper understanding of climate change, which is a key goal of EU research.;173076;173076;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6;FR;;;;1;0;0;1;0;0 212611;743605;NanoBioMap;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Nanoparticle Biointerface Mapping;2018-10-01;2020-09-30;;"The Nanoparticle Biointerface Mapping project builds on the extensive bionano interactions research in the group of Professor Kenneth Dawson at University College Dublin. In the NanoBioMap project I propose a cutting-edge interdisciplinary approach to develop a versatile tool allowing me to obtain detailed 3D maps of biomolecules at the surface of nanoparticles in complex biological media and study their importance for cell interactions. I will build on my extensive knowledge of nanomaterial science to develop this 3D mapping tool combining a tailor-made library of antibody-tagged quantum dots with electron microscopy 3D image reconstruction and X-ray elemental mapping. The resulting versatile method has multiple uses far beyond analyzing protein coronas. I envision applications of this state-of-the-art mapping tool in areas such as vaccine development, enzymatic catalysis on supported particles, cancer treatment and tracking of pollutants in water flows. The proposed project has 4 objective which will be reached over 24 months, within 13 work packages, including training-through-research and acquisition of transferable and complementary skills, contributing to the advancement of my career beyond this project, as a future independent researcher. The main objective is developing a tool to allow 3D mapping of protein epitopes at the surface of nanosized objects, with applications far beyond my test systems. The other objectives involve testing my tool to map epitopes in the protein corona at nanoparticles and study their interaction with cell receptors, focusing on spatial distribution of specific receptors. The proposal builds on my current extensive knowledge of nanomaterial synthesis, surface modification and characterization in complex environments adding a cell biology dimension, thus expanding my knowledge and career prospects.";175866;175866;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN;IE;;;;1;0;0;1;0;0 212806;759708;Enhancer3D;SIGNED;H2020-EU.1.1.;ERC-2017-STG;H2020;Regulatory genomics during Drosophila embryogenesis: dissecting enhancer-promoter interactions;2018-05-01;2023-04-30;;"In eukaryotes, the complex regulation of temporal- and tissue-specific gene expression is controlled by the binding of transcription factors to enhancers, which in turn interact with the promoter of their target gene(s) via the formation of a chromatin loop. Despite their importance, the properties governing enhancer function and enhancer-promoter loops in the context of the three-dimensional organisation of the genome are still poorly understood. My recent work suggests that (i) developmental genes are often regulated by multiple enhancers, sometimes located at great linear distances, (ii) the spatio-temporal activity of a large fraction of those enhancers remains unknown, (iii) enhancer-promoter interactions are usually established before the target gene is expressed and are largely stable during embryogenesis, and (iv) stable interactions seem to be associated with the presence of paused RNA Polymerase II at the promoter before gene activation. Building upon these results, we propose to advance to the next level in the dissection of enhancer-promoter interaction functionality in the context of Drosophila embryogenesis. Specifically, we will address three important questions: (i) What determines the specificity of promoter-enhancer interactions in a complex genome? (ii) Are enhancer-promoter interactions tissue-specific, and what are the drivers of this specificity? (iii) Are all enhancer-promoter interactions functional, and how does the activity of an enhancer relate to the expression of the gene it interacts with? To this end, my group will apply an interdisciplinary approach, combining state-of-the-art methods in genetics and genomics, including novel single-cell techniques, using Drosophila embryogenesis as a model system. Our results will provide a unique view of the functionality of enhancer-promoter interactions in a developing embryo, a significant step towards understanding the link between chromatin organisation and transcription regulation.";1770375;1770375;ERC-2017-STG;/ERC-STG;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FR;;;;1;0;0;1;0;0 212846;760973;DecoChrom;SIGNED;H2020-EU.2.1.3.;NMBP-05-2017;H2020;Decorative Applications for Self-Organized Molecular Electrochromic Systems;2018-01-01;2021-12-31;;"The DecoChrom project elevates printed graphics products to the age of interactivity, and empowers the creative industries with the tools and innovative advanced material sets to design and build aesthetically pleasing practical human interfaces to smart consumer goods and environments. The DecoChrom consortium develops printed electrochromics (EC) as the mass producible, print industry compatible, ultra low-power interactive graphics solution for ambient intelligence. DecoChrom will scale-up the production of advanced composite materials into 3 innovative ink EC colours, manufacturing process on different materials (plastic foil, paper, high-pressure laminates and 3D durable plastic parts), wide dissemination and creation of EC toolkits to introduce electrochromics to designers, makers and the printing industry, and finally the co-creation of more than 20 creative industry lead end-user prototypes and pilots for architecture, interior design, lifestyle and sports. The project brings together a strong interdisciplinary consortium of 15 partners, industry and research balanced, with state-of-the-art backgrounds in design, chemistry, printing, coatings and laminates, electronics system integration, and complete electrochromics solutions. This is complemented with the commitment of a multidisciplinary Industrial Advisory Board with representation of key industry end-users such as Ikea (furniture), Lego (toys), BMW (automotive), Fiskars (domestic tools), Hoffmann \ Krippner (printed electronics, industrial printing) and GSB Wahl (ink production).";7718834,5;6688150,88;H2020-NMBP-2017-two-stage;/IA;LAPIN YLIOPISTO;FI;"SONAE-INDUSTRIA DE REVESTIMENTOS SA;Teknologian tutkimuskeskus VTT Oy;FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.;TIKKURILA POLSKA S.A.;UNIVERSITE DE STRASBOURG;CENTRUM ORGANICKE CHEMIE SRO;WEPRODUCTISE LDA;DYNAMIC ENVIRONMENTS GROUP SL;THINGK SRL;VERTECH GROUP;YD YNVISIBLE SA;NOVA ID FCT - ASSOCIACAO PARA A INOVACAO E DESENVOLVIMENTO DA FCT;AALBORG UNIVERSITET;CARDIFF UNIVERSITY";"PT;FI;DE;PL;FR;CZ;ES;IT;DK;UK";;1;0;0;1;0;0 212337;760081;PMSB;SIGNED;H2020-EU.1.1.;ERC-2017-STG;H2020;Principles of Musical Structure Building: Theory, Computation, and Cognition;2018-03-01;2023-02-28;;"Music is a central human trait across all cultures and historical periods, involving a great rich variety of parameters, cognitive processes, and forms of structure building. The proposed project aims at advancing the understanding of human cognition and, specifically, the capacity to represent and process complex auditory sequences and syntactic structures by exploring the rich potential of music perception. Building on the PI’s previous work, this interdisciplinary research programme will be divided into three core strands: (A) The theoretical strand will be devoted to the investigation of formal principles that govern musical syntax and structure building in Western and non-Western music. Many current approaches share the expressive power of (tree-based) context-free grammars and are mostly confined to harmonic syntax only. Therefore, they face difficulty in expressing certain crucial syntactic phenomena in music. To address this lacuna, the theoretical strand will develop a novel unified theory of musical syntax that exceeds context-free complexity and reconciles harmonic structure with the constraints of voice leading within a single coherent framework. (B) Addressing the lack of machine-readable corpora in music research, a large corpus of digitized syntactic analyses will be compiled and published in the context of the project’s computational strand. Further, the unified syntax theory will be implemented based on a generalized parsing approach and graph grammars, and trained and evaluated using the analytical corpus. (C) The formal framework developed in (A) entails specific predictions about mental representations of musical structure that will be empirically tested in the experimental strand of the project. Particular focus will be on aspects of nonlocal dependency relations, learnability, revision, and tension. The outcomes of the project will make a significant contribution to both the field of music cognition and to the cognitive sciences in general.";1500000;1500000;ERC-2017-STG;/ERC-STG;ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE;CH;;;;1;0;0;1;0;0 212273;748649;MNEMONIC;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Magnetic Enzyme Metal Organic Framework Composites;2017-11-01;2019-10-31;;"The aim of this interdisciplinary project is to develop composites consisting of metal-organic frameworks (MOFs), magnetic nanoparticles (MNPs), and enzymes. The MOF coating protects the biomacromolecule from inhospitable conditions, and provides a permeable and selective molecular gate for the diffusion of substrates and products, thanks to its intrinsic and tunable porosity. External magnetic forces acts on the MNPs to allow for precise positioning of this ternary system. These highly efficient, long-lasting, robust, and dynamically positionable crystalline biocatalysts will be synthesized using the recently discovered biomimetic mineralization process, in which MOF precursors, metal ions, and organic ligands nucleates on the biomacromolecule without the need of stabilizing polymers or organic solvents, in aqueous solution at room temperature. This innovative technique has been proven successful for a wide range of protein and enzymes, and is currently the best performing procedure available for this class of porous material in terms of efficiency of enzyme encapsulation, absence of leaching, and reactions conditions and time. Key aspects of the project will be: the production of enzymes suitable for a multistep process; the synthesis and characterization of the composites; finally their integration into fluidic devices. The effects of process variables on particle size and morphology, enzyme loading and activity, MOF robustness, magnetic properties, and recyclability of the composite will be investigated with a multifaceted analytic approach. The long-term impact of this project includes technological benefits for industrial biotechnology, owing to the superior resistance of MOF-coated enzymes towards organic solvents, heat, and inhibitors, along with the presence of MNPs that permits the easy recovery of the MagEnzMOFs and their integration into fluidic reactors, to provide continuous production with high automation.";166156,8;166156,8;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;TECHNISCHE UNIVERSITAET GRAZ;AT;;;;1;0;0;1;0;0 212266;746442;HopeQNet;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Hopfield neural network dynamics in open quantum systems;2017-11-03;2019-11-02;;"Understanding how quantum effects can improve the performance of actual computing devices is an exciting and growing research area. However their role in neural networks (NNs), the complementary information process paradigm of classical computation is largely unexplored. The full translation of this paradigm at the quantum level ultimately requires to combine disordered spin-systems techniques, widely used in the study of classical NNs, together with the open quantum systems (OQSs) framework, in order to achieve their irreversible and non-linear dynamics. HopeQNet is the first step of an ambitious program that will lead, in a long term effort, to a new generation of quantum computing architectures, and is designed to deliver a first initial theoretical framework to investigate quantum effects in NNs, by considering the open quantum generalization of one of the most celebrated paradigms of NNs, the Hopfield model. This workhorse model will be simple and rich enough to: (i) apply well-developed tools from the theory of OQSs and establish a meaningful framework for a quantum NN; (ii) evaluate the potential gain due to quantum effects in this specific quantum NN architecture; (iii) engineering and modeling a proof-of-principle experiment of a Rydberg quantum simulator implementing it. HopeQNet combines the knowledge of the Applicant, who pioneered the use of disordered spin-systems in quantum many-body optical systems during his PhD (and will provide to the Host this unique expertise), together with the internationally recognized experience of the Supervisor in open quantum many-body systems and Rydberg atoms (who will mentor the Applicant throughout the training-through-research activity proposed here). This interdisciplinary combination of expertise is uniquely suited to carry out this first step of an ambitious 5-to-10 years program that will lead the Applicant to join one of the major EU institution working on quantum theory as an independent scientist.";183454,8;183454,8;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;THE UNIVERSITY OF NOTTINGHAM;UK;;;;1;0;0;1;0;0 211796;726360;MOLEMAT;SIGNED;H2020-EU.1.1.;ERC-2016-COG;H2020;Molecularly Engineered Materials and process for Perovskite solar cell technology;2017-11-01;2022-10-31;;Societal pressure to develop inexpensive yet efficient solar energy conversion requires a new approach. Recently emerged organic-inorganic perovskites, offer to harvest light at cost effective price. Perovskites hold merits to the existing materials, however, a fundamental challenge for high performance devices is to optimize the crystals for maximize charge carrier generation and minimize recombination losses. Their widespread use is, however, limited by insufficient stability, scalability and reproducibility. We have recently developed new concepts to fabricate efficient and stable perovskite solar cells at lab scale that are potentially up-scalable to industrial production. MOLEMAT will accomplish this by, pioneering innovative methods and will demonstrate that molecularly engineered materials enable the tuning of the charge transport and interface. Our interdisciplinary approach, combining materials science, chemistry, device physics and engineering, will not only lead to improvements in the performance and stability of perovskite solar cell beyond 24% at lab scale, but will also provide deep insights in the functioning of solar cells. The success of MOLEMAT will rapidly advance the field by enabling reproducible and stable performance adding a significant value with respect to current state of the art. However, for making it marketable product, several developments are required and the MOLEMAT targets will provide relevant answers to three key limitations: encapsulation, stability and cost competitive materials. MOLEMAT envisages the development of 30×30 cm2 modules, with a power conversion efficiency of c.a 18% and a lifetime of 10\ years. MOLEMAT is divided into two parallel research directions, a fundamental research line, dealing with rational design of materials and to gain its understanding. Simultaneously an applied research line targets the development of module by the identification of scale up process to pave the way for its industrialization.;1878085;1878085;ERC-2016-COG;/ERC-COG;FUNDACION BCMATERIALS - BASQUE CENTRE FOR MATERIALS, APPLICATIONS AND NANOSTRUCTURES;ES;;;;1;0;0;1;0;0 212306;758053;QUNNECT;SIGNED;H2020-EU.1.1.;ERC-2017-STG;H2020;A Fiber Optic Transceiver for Superconducting Qubits;2018-02-01;2023-01-31;;"Many researchers in basic science and large IT companies are convinced that superconducting quantum processors will soon help solve complex problems faster, improve optimization and simulation, and boost the progress in artificial intelligence. A worldwide quantum web is the next logical step. It would not only improve communication security, it represents the key to unlock the full potential of the new quantum-computing paradigm. Unfortunately, research in optical quantum networks and superconducting devices has progressed largely independently so far. While superconducting qubits are ideally suited for on-chip integration and fast processing, they are problematic for quantum communication. In fact, no solution exists to connect remote qubits via a room temperature link. The small energy scales in the electrical circuit make the fragile information carriers (single microwave photons) susceptible to interference, thermal noise and losses, which has hindered any significant progress in this direction. Only just now we have gained sufficient insight into low loss materials, the required fabrication technology, and the precision measurement techniques necessary to bridge the two worlds, by controlling individual photons and phonons quantum coherently. We propose to integrate silicon photonics for low-loss fiber optic communication with superconducting circuits for quantum processing on a single microchip. As intermediary transducer we will focus on two approaches: (1) quantum ground state cooled nanoscale mechanical and (2) low-loss electro-optic nonlinear circuit elements. The novelty of our approach is the tight on-chip integration facilitated by the PIs interdisciplinary background in both, superconducting circuits and silicon nanophotonics. Integration will be the key for realizing a low-loss and high-bandwidth transceiver, for preparing remote entanglement of superconducting qubits, and for extending the range of current fiber optic quantum networks.";1500000;1500000;ERC-2017-STG;/ERC-STG;Institute of Science and Technology Austria;AT;;;;1;0;0;1;0;0 212288;756194;ENERGYA;SIGNED;H2020-EU.1.1.;ERC-2017-STG;H2020;ENERGY use for Adaptation;2018-03-01;2023-02-28;;"ENERGYA will improve our understanding of how energy and energy services can be used by households and industries to adapt to the risk posed by climate change. Specifically, the project will develop an interdisciplinary and scalable research framework integrating data and methods from economics with geography, climate science, and integrated assessment modelling to provide new knowledge concerning heterogeneity in energy use across countries, sectors, socioeconomic conditions and income groups, and assess the broad implications adaptation-driven energy use can have on the economy, the environment, and welfare. The key novelty of ENERGYA is to link energy statistics and energy survey data with high spatial resolution data from climate science and remote sensing, including high-resolution spatial data on meteorology, population and economic activity distribution, electrification, and the built environment. ENERGYA has three main objectives. First, it will produce novel statistical and econometric analyses for OECD and major emerging countries (Brazil, Mexico, India, and Indonesia) to shed light on the underlying mechanisms driving energy use. Second, it will infer future potential impacts from long-run climate and socioeconomic changes building on historical empirical evidence. Third, it will analyse the macro and distributional implications of adaptation-driven energy use with an economy-energy model characterising the distribution of energy use dynamics across and within countries. Given the central role of energy as multiplier for socioeconomic development and as enabling condition for climate resilience, the research proposed in ENERGYA will result in timely insights for the transition towards sustainability described by the Sustainable Development Goals adopted by the United Nations as well as the Paris International Climate Agreement.";1495000;1495000;ERC-2017-STG;/ERC-STG;UNIVERSITA CA' FOSCARI VENEZIA;IT;FONDAZIONE CENTRO EURO-MEDITERRANEO SUI CAMBIAMENTI CLIMATICI;IT;;1;0;0;1;0;0 212463;777717;CTFF;SIGNED;H2020-EU.1.3.3.;MSCA-RISE-2017;H2020;Control of turbulent friction force;2017-12-01;2020-11-30;;CTFF is a major interdisciplinary project that combines wisdoms in three academic disciplines: Heat Transfer, Fluid Physics and Plasma Physics, to address the research problem on both active and passive control of turbulent friction force. The main focus is on developing techniques for the control of near-wall turbulent structures and the reduction of turbulent friction force, specifically at conditions relevant to engineering practices, by coordinating the efforts of European, the US and Chinese experts specialized in these three different but overlapping domains. New materials will be examined, novel numerical algorithms will be developed, and the numerical results will be tested in physical experiments. In brief, the main objective of this project is to coordinate the action of a group of Universities and enterprises, with complementary expertise in three disciplines from European countries, China and the US, to build and test an optimal solution for the reduction of turbulent friction drag, thereby facilitating the successful implementation of friction force control in engineering practices.;706500;504000;H2020-MSCA-RISE-2017;/MSCA-RISE;THE UNIVERSITY OF NOTTINGHAM;UK;"R.TECH;KUNGLIGA TEKNISKA HOEGSKOLAN;OFFICE NATIONAL D'ETUDES ET DE RECHERCHES AEROSPATIALES;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD";"FR;SE;UK";;1;0;0;1;0;0 211372;769705;WE4AHA;SIGNED;H2020-EU.3.1.4.;SC1-HCO-17-2017;H2020;Widening the support for large scale uptake of Digital Innovation for Active and Healthy Ageing;2017-09-01;2020-12-31;;"WE4AHA will advance the effective, large-scale uptake and impact of Digital Innovation for Active and Healthy Ageing (AHA), building on a comprehensive set of support and promotion services. Through WE4AHA’s centralised administration, coordination and external communication, the relevant stakeholders will be mobilised to help develop and implement three EU guided activities: Innovation to Market (I2M), Blueprint Digital Transformation of Health and Care for the Ageing Society, and EIP on AHA. WE4AHA will support the definition and execution of an I2M plan, further development of the Blueprint to drive the policy vision on digital innovation, and the consolidation of EIP on AHA Action Groups and Reference Sites. It will connect demand- and supply-side stakeholders through matchmaking, twinning, assessing innovative interventions using MAFEIP, and fostering engagement and many other support activities. It will leverage additional private and public investments by mobilising a growing number of stakeholders in Europe’s digital health and care and silver economy sectors - industry, public authorities, end users, financial institutions, investors, insurers, and research communities committed to innovate on a large-scale. WE4AHA will draw on its numerous, strong synergies and links to relevant H2020 R&I actions and other EU and international programmes. The highly interdisciplinary consortium will ensure the proper execution of the work plan by leveraging the partners’ access to expertise and evidence. The consortium composition is an unparalleled matching of partners with strategic competences in health and active ageing and leading experts in policy analysis, research and innovation oriented to business, ICT enabling technologies, stakeholder engagement, communication, dissemination and the multiplier effect. Additional support is provided through a pool of experts and an Advisory Board of key stakeholder organisations with high-level competences in relevant fields.";2000000;2000000;H2020-SC1-2017-CNECT-1;/CSA;FUNKA NU AB;SE;"EMPIRICA GESELLSCHAFT FUER KOMMUNIKATIONS- UND TECHNOLOGIE FORSCHUNG MBH;AZIENDA OSPEDALIERA UNIVERSITARIA FEDERICO II;EUROPEAN HEALTH TELEMATICS ASSOCIATION;EUROPEAN REGIONS RESEARCH AND INNOVATION NETWORK ASBL;CONNECTED HEALTH ALLIANCE CIC;The Lisbon Council for Economic Competitiveness and Social Renewal asbl;TICBIOMED TECNOLOGIAS DE LA INFORMACION PARA LA SALUD EN LA REGION DE MURCIA ASOCIACION;AGE PLATFORM EUROPE;OPEN EVIDENCE";"DE;IT;BE;UK;ES";;1;0;0;1;0;0 211248;750557;MECHADIAN;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Mechanobiology of the cellular circadian clock;2018-06-29;2020-06-28;;"The circadian clock is the biological mechanism that directs the physiological ~24 hour oscillations that most living organisms undergo to anticipate the daily pattern of light. In mammals, that rhythmicity results from a highly conserved genetic circuit –based on transcriptional and post-transcriptional regulation– that works synchronously at a cellular level and differs among tissues. Around the 10% of the mammalian proteins, including essential components of the cell cycle and differentiation pathways have been categorised as circadian. Thus, a clock dysregulation may have pathological consequences, which is the case in some types of cancer. Although synchronous circadian cells share a common mechanical microenvironment, the contribution of mechanics to the clock maintenance has never been addressed. To fill this gap, the aim of this project is to unravel a) the impact of the mechanical microenvironment on the cellular clock, b) the influence of circadian oscillations on the mechanical behaviour of the cells and c), the interplay between mechanics and the clock during stem cell differentiation. To achieve these goals, we will combine state-of-the-art technologies in cell mechanics, molecular biology, imaging, and computational modelling. As model system we will use entrained MCF-10a and PHK stem cells. By subjecting them to a range of extracellular matrix rigidities, we will measure the influence of mechanics on the circadian expression of core clock, cytoskeleton and differentiation genes. We will then use traction force microscopy to study the rhythmicity of cell mechanics and, through computational tools, we will link gene expression patterns and force oscillatory behaviour in order to elucidate the molecular basis of the ‘biomechanical clock’. This interdisciplinary study will add a new layer of regulation to both cell mechanics and the circadian clock. As such, the results obtained here will potentially impact on the field of chronomedicine.";158121,6;158121,6;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;FUNDACIO INSTITUT DE BIOENGINYERIA DE CATALUNYA;ES;;;;1;0;0;1;0;0 212275;750086;Aural Paris;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Aural Paris: The Changing Identities of The City of Sound in Music, Film and Literature, 1870-1940.;2018-09-01;2020-08-31;;This project examines the creative assimilation of the city of Paris into the music, film and literature of the French Third Republic (1870-1940). In this period, demarcated by two war defeats, France had to find its new place within global politics, and the arts participated vividly in these debates. As the city of Paris changed rapidly from a world-leading metropolis to an impoverished city in need of architectural, political and moral reconstruction, its symbols acquired different connotations. This changing backdrop offers the ground for the study, which analyses how singer/songwriters, composers, authors and filmmakers —such as Victor Fournel, Aristide Bruant, Jean Cocteau, Gustave Charpentier, René Clair and Pierre Mac Orlan— used the city and its sounds as creative force and political metaphor. The study of overlooked, or totally ignored, archival sources and cultural artefacts will enlighten our knowledge of how street culture and city life intersected with art. The proposed research plan analyses ‘panoramic literature’ in the late 19th century, the development of the city as a musical stage, the corpus of compositions about Paris, street music and sound in the transition from silent to sound cinema, and the composition of populist Parisian songs by authors of urban life-writing. The project allows us to re-evaluate the politics of the city soundscape and its role in defining French identity. It also reassesses established notions of modernity and its interaction with the urban context though the study of everyday sounds and music. By embracing novel ecomusicological methodologies, this project is timely in joining current debates within musicology and cultural geography on the capacities of sound to produce a sense of space and place. The research will create orthodox academic outputs, exploit novel dissemination and communication strategies, and consolidate an international interdisciplinary network on urban musicology.;173076;173076;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;ECOLE DES HAUTES ETUDES EN SCIENCES SOCIALES;FR;;;;1;0;0;1;0;0 212314;758430;SWFsEUROPE;SIGNED;H2020-EU.1.1.;ERC-2017-STG;H2020;Legitimacy, Financialization, and Varieties of Capitalism: Understanding Sovereign Wealth Funds in Europe;2018-01-01;2022-12-31;;The number and size of sovereign wealth funds (SWF) has grown substantially in the last decade, leading to an unsettled debate regarding their legitimacy in the global political economy. Some suggest they represent the (re)emergence of state-led capitalism subject to geopolitical motivations that threaten free markets. For others, SWFs represent a source of long-term patient capital capable of mitigating market short-termism. Either way, SWFs challenge the norm, particularly in the West, that financial markets are spaces of exchange for non-state actors. In three complementary and interdisciplinary work programmes the SWFsEUROPE project will explain the evolving and variegated pattern of ‘sovereign fund capitalism’ in Europe, developing a new theory of the relationship between states and global finance. First, the project breaks new ground by explaining and theorizing how the legitimacy of SWFs as commercially oriented investors is performed when they are still entities of the state. No study has critically examined how legitimacy is performed via mechanisms such as the International Forum of Sovereign Wealth Funds and the Santiago Principles, or the growing evidence of collaboration with cognate institutional investors (e.g. pension funds). Second, this projects seeks a multi-layered explanation of the uneven pattern of investment flows and stocks of foreign SWFs into European countries through hypothesis testing of aggregate investment data with different theories of national-institutional variety, coupled with a comparative analysis of the bilateral investment-promotion relationships of investment-receiving countries. Third, the project will compare the growth and development of European SWFs. There is no comparative study exploring why some states are sponsors of an SWF (e.g. Italy, France, Ireland) and others are not (e.g. UK), what the motivations are and how they are made legitimate.;1414722;1414722;ERC-2017-STG;/ERC-STG;UNIVERSITEIT MAASTRICHT;NL;UNIVERSITY OF BRISTOL;UK;;1;0;0;1;0;0 211903;765912;DRIVE;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2017;H2020;Driving next generation autophagy researchers towards translation;2017-11-01;2021-10-31;;"The manipulation of autophagy has an enormous therapeutic potential to revolutionize the way we currently treat cancers, neurodegenerative disorders, inflammatory and infectious diseases. Despite the great promises made by pioneering medical studies, the still limited applied research on autophagy has hampered the translation of fundamental knowledge into clinical-grade products and improved healthcare. Applied autophagy research is essential to understand the roles of autophagy in the different physiological and pathological situations, to generate (disease) models and develop biomarkers and assays to assess its progress. The goal of the ETN Driving next generation autophagy researchers towards translation (DRIVE) is to train young scientists to fill this gap. DRIVE will equip its ESRs with an unique combination of knowledge and experimental expertise that are brought together in this consortium by the different partners. The realization of their projects in applied autophagy research will benefit of an exceptional interdisciplinary platform integrating cell biology, biochemistry, molecular biology, genetics, chemistry and “omics” approaches. In addition, DRIVE ESRs will acquire competencies to exploit the results for the development of products and techniques of commercial value. These ESRs will also be trained in disseminating results and knowledge through modern channels of communication.";3890064,96;3890064,96;H2020-MSCA-ITN-2017;/MSCA-ITN-ETN;ACADEMISCH ZIEKENHUIS GRONINGEN;NL;"QPS NETHERLANDS BV;HELSINGIN YLIOPISTO;INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE;WEIZMANN INSTITUTE OF SCIENCE;FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.;ANAXOMICS BIOTECH, S.L.;AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS;UNIVERSITETET I OSLO;EBERHARD KARLS UNIVERSITAET TUEBINGEN;ADJUVATIS;UNIVERSITAETSKLINIKUM FREIBURG;INSTITUTE OF CANCER RESEARCH - ROYAL CANCER HOSPITAL;TURUN YLIOPISTO;KING'S COLLEGE LONDON";"NL;FI;FR;IL;DE;ES;NO;UK";;1;0;0;1;0;0 212050;753569;TRACT;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;TRAvelling Ceramic Technologies as markers of human mobility in the Aegean;2017-10-01;2019-09-30;;The main aim of TRACT is to demonstrate that the informed and interdisciplinary study of ancient pottery can shed new light on past human mobility. Based on the premise that the spread of technology involved in pottery making requires the physical movement of people, the project will adopt an inter-disciplinary methodology designed to investigate instances of technological transfer and hence mobility of potters. The methodology comprises macroscopic study of the vessel-forming methods in combination with petrographic and chemical analysis of pottery and raw material samples. An important addition is the study of modern instances of potters’ mobility in the Aegean. Altogether, this represents a novel approach, which will be employed to a specific study focused on potters from the island of Aegina during the Late Bronze Age. TRACT will investigate the spread of a particular pottery tradition developed on the island of Aegina along the Euboean Gulf, an important corridor that facilitated movement of goods and people. Furthermore, the chosen case study will aim to shed light on the underpinnings of such movement, its duration, scale, as well as interaction of potters with new landscapes and receiving communities. Therefore, TRACT will contribute to the current debate on mobility by presenting thoroughly researched case study of craftsmen mobility, and elaborate a coherent methodology that can be universally applied. The choice of the Fitch Laboratory of the British School at Athens as a hosting institution will not only enable a high-level training through research but also, due to the supervisor’s interest in mobility of potters’ mobility and previous research on pottery production on the island of Aegina, it constitutes a perfect match that will provide a substantial boost to career opportunities for the experienced researcher and strengthen the position of the Laboratory as a centre of excellence for the study of craftspeople mobility.;164653,2;164653,2;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;BRITISH SCHOOL AT ATHENS;UK;;;;1;0;0;1;0;0 211750;764690;sCO2-Flex;SIGNED;H2020-EU.3.3.2.;LCE-28-2017;H2020;SUPERCRITICAL CO2 CYCLE FOR FLEXIBLE AND SUSTAINABLE SUPPORT TO THE ELECTRICITY SYSTEM;2018-01-01;2020-12-31;;"Current fossil-fuel power plants have been designed to operate in base-load conditions, i.e to provide a constant power output. However, their role is changing, due to the growing share of renewables, both in and outside the EU. Fossil-fuel plants will increasingly be expected to provide fluctuating back-up power, to foster the integration of intermittent renewable energy sources and to provide stability to the grid. However, these plants are not fit to undergo power output fluctuations. In this context, sCO2-Flex consortium addressees this challenge by developing and validating (at simulation level the global cycle and at relevant environment boiler, heat exchanger(HX) and turbomachinery) the scalable/modular design of a 25MWe Brayton cycle using supercritical CO2, able to increase the operational flexibility and the efficiency of existing and future coal and lignite power plants. sCO2-Flex will develop and optimize the design of a 25MWe sCO2 Brayton cycle and of its main components (boiler, HX, turbomachinery, instrumentation and control strategies) able to meet long-term flexibility requirements, enabling entire load range optimization with fast load changes, fast start-ups and shut-downs, while reducing environmental impacts and focusing on cost-effectiveness. The project, bringing the sCO2 cycle to TRL6, will pave the way to future demonstration projects (from 2020) and to commercialization of the technology (from 2025). Ambitious exploitation and dissemination activities will be set up to ensure proper market uptake. Consortium brings together ten partners, i.e academics (experts in thermodynamic cycle/control/simulation, heat exchanging, thermoelectric power, materials), technology providers (HX, Turbomachinery) and power plant operator (EDF-coordinator) covering the whole value chain, constituting an interdisciplinary group of experienced partners, each of them providing its specific expertise and contributing to the achievement of the project’s objectives.";5630855;5630855;H2020-LCE-2017-RES-CCS-RIA;/RIA;ELECTRICITE DE FRANCE;FR;"NUOVO PIGNONE SRL;FIVES CRYO;ZABALA INNOVATION CONSULTING, S.A.;CENTRUM VYZKUMU REZ S.R.O.;UNIVERSITAET DUISBURG-ESSEN;POLITECNICO DI MILANO;UNIVERSITAET STUTTGART;UJV REZ, a. s.;RINA CONSULTING - CENTRO SVILUPPO MATERIALI SPA";"IT;FR;ES;CZ;DE";;1;0;0;1;0;0 211686;766214;META-CAN;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2017;H2020;Targeting the metabolism-immune system connections in Cancer;2017-09-01;2021-08-31;;"'Cancer cells show common features of profound metabolic changes and escape from the immune system, independently of their tissue of origin. These metabolic adaptations are not limited to glucose metabolism (the 'Warburg effect') but are more general and affect several metabolic pathways in cancer cells as well as in the stroma, including immune cells. This network will explore how nutrients and hypoxia regulate the tumor-immune system interplay, and how this communication is controlled by oncogenes, metabolic regulators and current or potential drugs targeting metabolism. Understanding how metabolism can affect tumor cells and the anti-cancer immune response represents a potential therapeutic intervention point that can be exploited to develop novel therapies and new diagnostic and prognostic markers. The development of therapies targeting cancer metabolism is hampered by: 1) the complexity of the regulation that metabolism exerts on many different tumor layers, which requires multidisciplinary collaborations, and 2) the shortage of scientists that can navigate with ease between academic, industrial and clinical sectors and have the scientific and complementary skills to convert research findings into commercial and clinical applications. This network provides a pan-European interdisciplinary and intersectoral training program of excellence bringing young researchers together with World leading academics, clinicians, pharma industry members, corporate research and dissemination and outreach specialists. As part of the research training, the consortium will conduct a coherent and integrated set of hypothesis-driven research projects that are aimed at discovering, describing and exploiting how metabolism at the cell and the whole body levels is integrated with modulation of cell death susceptibility and the immune response in the context of cancer. '";3831957,72;3831957,72;H2020-MSCA-ITN-2017;/MSCA-ITN-ETN;FUNDACIO INSTITUT D'INVESTIGACIO BIOMEDICA DE BELLVITGE;ES;"MEDIZINISCHE UNIVERSITAET WIEN;INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE;ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS;APPLIED RESEARCH USING OMIC SCIENCES SL;VIB;TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY;IBM ISRAEL - SCIENCE AND TECHNOLOGY LTD;Academisch Medisch Centrum bij de Universiteit van Amsterdam;UNIVERSITE PARIS DESCARTES;EVOTEC (FRANCE) SAS";"AT;FR;ES;BE;IL;NL";;1;0;0;1;0;0 211550;764927;YEASTDOC;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2017;H2020;Yeast Biotechnology Doctoral Training Programme;2017-09-01;2021-08-31;;YEASTDOC is a European Joint Doctoral programme to train researchers for outstanding careers as leaders in the field of yeast biotechnology. Six academic institutions are joined by 7 industry and 2 training partner organisations to offer an international training programme leading to the award of joint PhD degrees. The interdisciplinary, trans-sectoral research topic takes advantage of recent technological developments to link fundamental research in yeasts with new applications in the beverage and white biotechnology sectors. 12 Early Stage Researchers will each carry out a 36-month joint PhD project between two academic institutions, spending at least 12 months at each partner university in a different European country. All projects include an industry co-supervisor from a partner organisation and ESRs have an industry secondment of 4-6 months to gain intersectoral experience. Additional research training is provided via summer schools, scientific conferences, doctoral seminars and practical workshops. Further training in innovation-related skills will be provided through network-wide courses that include technology transfer management and entrepreneurship. Transferrable skills training is delivered locally in graduate schools and by network courses in responsible research and innovation, scientific writing, and research leadership. ESRs will disseminate research outcomes in the scientific sector and will participate in outreach activities to engage targeted public audiences in research. All training will receive ECTS credits and be mutually recognised by all academic partners. A joint governance and ESR monitoring structure, including external experts, will assure the quality of the training programme. The long-term impact of the EJD will be an accredited, sustainable, inter-institutional doctoral programme that delivers high quality PhD graduates to drive research and innovation to maintain competitiveness in European biotechnology.;3094944,48;3094944,48;H2020-MSCA-ITN-2017;/MSCA-ITN-EJD;UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK;IE;"UNIVERSIDADE DO MINHO;JACOBS UNIVERSITY BREMEN GGMBH;UNIVERSITA' DEGLI STUDI DI MILANO-BICOCCA;INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE;UNIVERSITY OF LEICESTER";"PT;DE;IT;FR;UK";;1;0;0;1;0;0 211716;740342;PASTRES;SIGNED;H2020-EU.1.1.;ERC-2016-ADG;H2020;Pastoralism, Uncertainty and Resilience: Global Lessons from the Margins;2017-10-01;2022-09-30;;"Existing institutions, legal frameworks and governance systems are not equipped to respond to growing global uncertainties and the challenges of building resilience. Radical new thinking is needed. Important lessons potentially can come from surprising quarters. Drawing insights from pastoral areas across three continents, we will ask: What lessons can we learn from pastoral systems responding to rapid change that help us understand how to live with uncertainty and build resilience? Learning from the margins – through a reversal in conventional policy learning and debate - this project will draw out principles from deeply-embedded, culturally-rich responses to rapid change and uncertainty in pastoral areas in Africa (Borana, Ethiopia), Asia (Qinghai-Tibet, China) and Europe (Sardinia, Italy). Working in a world-class team - including the PI (Prof. Ian Scoones), an experienced post-doctoral researcher (Dr Michele Nori) and three PhD students, together with local partners - we will explore how to respond to uncertainty and build resilience across three themes: i) environment and resources, ii) commodification and markets and iii) institutions and governance, while building the interdisciplinary research capacities of the team. Through a process of theory-building, emerging from detailed empirical research in our three sites, we will engage in dialogue with wider debates across five areas – environmental and climate change, finance and commodity markets, infrastructure design, migration policy and conflict and security - about how to respond to risk and uncertainty and build resilience, offering both new theory and practical responses. The research will significantly extend past work through a path-breaking, cross-disciplinary reconceptualization of uncertainty and resilience, linking the experiences of marginal pastoralists to wider, global resilience challenges.";2499126,5;2499126,5;ERC-2016-ADG;/ERC-ADG;INSTITUTE OF DEVELOPMENT STUDIES;UK;EUROPEAN UNIVERSITY INSTITUTE;IT;;1;0;0;1;0;0 211666;754345;INVITE;SIGNED;H2020-EU.1.3.4.;MSCA-COFUND-2016;H2020;INnovative Verona university’s Inter-disciplinary, Inter-sectoral and International Training Experience;2017-10-01;2022-09-30;;"INVITE is a doctoral programme at the University of Verona (UNIVR), Italy, with a strong inter-sectoral, inter-disciplinary and international research and training dimension. The project is co-financed by the Regione del Veneto and involves many partner organisations: 17 universities and research centres in Europe and beyond, 13 enterprises and organisations from the economic sector, 3 public organisations and 1 network. INVITE offers a total of 14 PhD positions to train early-stage researchers in scientific disciplines within the following four main scientific domains: Natural and Engineering Sciences, Life and Health Sciences, Humanities, and Law and Economics. INVITE aims to: 1. Attract young, talented, international fellows to follow a high-quality interdisciplinary doctoral programme at the UNIVR; 2. Encourage inter-sectoral and international mobility, thanks to collaborations with a wide network of Italian and European partner organisations in both the academic and non-academic sectors; 3. Provide the early-stage researchers (ESRs) with a comprehensive set of transferable skills for intellectual property rights (IPR) management, the exploitation of research results, the management of ethically-relevant research including the gender dimension in research, grant writing and project management, and the design and implementation of outreach and dissemination activities; 4. Support ESRs with a specific counselling service to improve their employability at the end of the doctoral programme; 5. Reinforce UNIVR capacities to host talented international researchers in a high-quality working environment. The ultimate goal is to train a new generation of researchers in a wide range of disciplines and to provide them with the ability to establish professional collaborations with academic institutions and/or the private sector at the Italian and European levels. INVITE will also improve the already well-established and successful doctoral programme at UNIVR.";2197440;1098720;H2020-MSCA-COFUND-2016;/MSCA-COFUND-DP;UNIVERSITA DEGLI STUDI DI VERONA;IT;;;;1;0;0;1;0;0 211749;765256;SALTGIANT;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2017;H2020;Understanding the Mediterranean Salinity Crisis;2018-01-01;2021-12-31;;"As society moves into an era where environmental change has an ever-growing place in the political agenda, the demand for a new generation of scientists working at the interface between the natural and social sciences is growing. SALTGIANT contributes to satisfy this demand within a rare cross-disciplinary network of natural and social scientists dedicated to understanding the formation of the Mediterranean Salt Giant, one of the largest salt deposits on Earth, and its implications for sub-seafloor microbial life, risk assessment in the oil industry, geo-economics of the Mediterranean region and the history of oceanography. SALTGIANT will bring together 22 academic organizations (11 beneficiaries, 11 partners), 2 private sector Oil&Gas companies and 1 specialist in transferable skills training from 8 European countries to stimulate interdisciplinary and intersectorial knowledge exchange between geologists, geophysicists, geochemists, microbiologist, geographers and historians in a network with PhD students at its core. SALTGIANT combines (i) geological and geochemical field work, (ii) laboratory measurements and experiments, (iii) numerical modeling at a wide range of spatial and temporal scales and (iv) empirical social sciences data collection and analysis, guaranteeing exposure of the research fellows to state-of-the-art scientific knowledge and hands-on practical training in a field rich in applications of both intellectual and societal relevance. Through its innovative blend of training and research activities, SALTGIANT will boost the employability of its research fellows in academia and in the private sector, particularly the energy sector, including Oil & Gas and geothermal, resource management, geological storage and numerical modeling, as well as in governmental agencies (Ministries of the Environment, Sustainable Development and Energy), international organizations (European Environment Agency, EEA; United Nations Environmental Program, UNEP) and NGOs.";3893087,88;3893087,88;H2020-MSCA-ITN-2017;/MSCA-ITN-ETN;INSTITUT DE PHYSIQUE DU GLOBE DE PARIS;FR;"UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6;UNIVERSITAET HAMBURG;FONDATION NATIONALE DES SCIENCES POLITIQUES;UNIVERSITA DEGLI STUDI DI PALERMO;AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS;UNIVERSITY OF ESSEX;ISTITUTO NAZIONALE DI OCEANOGRAFIA E DI GEOFISICA SPERIMENTALE;Ministry of National Infrastructure, Energy and Water Resources;UNIVERSITEIT UTRECHT;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;UNIVERSIDAD DE SALAMANCA;SORBONNE UNIVERSITE;NATURAL ENVIRONMENT RESEARCH COUNCIL";"FR;DE;IT;ES;UK;IL;NL";;1;0;0;1;0;0 211614;742985;ETAP;SIGNED;H2020-EU.1.1.;ERC-2016-ADG;H2020;Tracing Evolution of Auxin Transport and Polarity in Plants;2018-01-01;2022-12-31;;"Multicellularity in plants evolved independently from other eukaryotes and presents a unique, alternative way how to deal with challenges of life. A major plant developmental module is the directional transport for the plant hormone auxin. The crucial components are PIN auxin transporters, whose polar, subcellular localization determines directionality of auxin flow through tissues. PIN-dependent auxin transport represents a unique model for studying the functional link between basic cellular processes, such as vesicle trafficking and cell polarity, and their developmental outcome at the level of the multicellular organism. Despite decades of intensive research, the classical approaches in the established models are approaching their limits and many crucial questions remain unsolved, in particular related to PIN structure, regulatory motifs and evolutionary origin I propose to start a new direction in my research using an evolutionary perspective. This promises to overcome current limitations and provides not only (i) interesting insights into PIN evolution and diversification, but also (ii) a unique opportunity to study how evolutionary conserved cellular mechanisms of e.g. endocytic trafficking evolved specific plug-ins to make them subject to plant-specific regulations. The characterization of (iii) prokaryotic PIN origin will provide a so urgently needed (iv) entry into PIN structural studies. To achieve these goals, we will also establish novel (v) genetic and cell biological models in the ancestral lineage of the land plants that will be of a great use for any plant evolutionary studies. The intellectual and methodological challenges of such interdisciplinary strategy combining several lower and higher plant models are obvious, but our preliminary results at several fronts promise its feasibility and success to gain deeper understanding of exciting questions on evolution and mechanisms behind the coordination and specification of developmental programs.";2410292;2410292;ERC-2016-ADG;/ERC-ADG;Institute of Science and Technology Austria;AT;;;;1;0;0;1;0;0 211654;765378;HYCOAT;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2017;H2020;A European Training Network for Functional Hybrid Coatings by Molecular Layer Deposition;2018-01-01;2021-12-31;;HYCOAT is the first ETN at the intersection of chemistry, physics, materials science and engineering dealing with the synthesis and applications of hybrid coatings grown by molecular layer deposition (MLD). With self-limiting binary reactions, MLD is the ideal ultra-thin film deposition technique, offering unique advantages for growing uniform, conformal hybrid films providing precise and flexible control over the film thickness and chemical composition at molecular scale. This new field of MLD is pioneered at nanoscience laboratories across Europe. HYCOAT provides a European approach to facilitate an interdisciplinary and multi-environment (Universities, Research Centers, SMEs & Large industries) platform for training a new generation of MLD researchers. A coordinated effort of 10 beneficiaries and 16 partner organizations from 7 European countries (Belgium, Finland, Germany, Ireland, Netherlands, Norway and Spain), HYCOAT targets the development of novel precursor chemistries, processes, characterisation and modelling of MLD and the demonstration of hybrid coatings in four key high impact fields of application relevant for European industries, in packaging, biomedical, electronics and batteries. Understanding and engineering of hybrid coatings by MLD is essential for its wide range of applications and the interaction with European high-tech industry is ensured through the active participation of 10 industries, 2 university hospitals and a synchrotron facility. Training will take place through research projects, courses and workshops, with the emphasis on self-directed, hands-on, collaborative learning. This European knowledge alliance with an inter- and trans-disciplinary mobility and an intense collaboration between the private and public entities is needed to equip the next generation of researchers and extrapolate Europe’s current pioneering role in the science of MLD towards a leadership in economic and societal impact of innovations enabled by MLD.;3898797,84;3898797,84;H2020-MSCA-ITN-2017;/MSCA-ITN-ETN;UNIVERSITEIT GENT;BE;"Asociacion - Centro de Investigacion Cooperativa en Nanociencias - CIC NANOGUNE;HELSINGIN YLIOPISTO;NEDERLANDSE ORGANISATIE VOOR TOEGEPAST NATUURWETENSCHAPPELIJK ONDERZOEK TNO;INTERUNIVERSITAIR MICRO-ELECTRONICA CENTRUM;AALTO KORKEAKOULUSAATIO SR;RUHR-UNIVERSITAET BOCHUM;UNIVERSITETET I OSLO;KATHOLIEKE UNIVERSITEIT LEUVEN;UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK";"ES;FI;NL;BE;DE;NO;IE";;1;0;0;1;0;0 211385;724557;ALTERUMMA;SIGNED;H2020-EU.1.1.;ERC-2016-COG;H2020;Creating an Alternative umma: Clerical Authority and Religio-political Mobilisation in Transnational Shii Islam;2018-01-01;2022-12-31;;"This interdisciplinary project investigates the transformation of Shii Islam in the Middle East and Europe since the 1950s. The project examines the formation of modern Shii communal identities and the role Shii clerical authorities and their transnational networks have played in their religio-political mobilisation. The volatile situation post-Arab Spring, the rise of militant movements such as ISIS and the sectarianisation of geopolitical conflicts in the Middle East have intensified efforts to forge distinct Shii communal identities and to conceive Shii Muslims as part of an alternative umma (Islamic community). The project focusses on Iran, Iraq and significant but unexplored diasporic links to Syria, Kuwait and Britain. In response to the rise of modern nation-states in the Middle East, Shii clerical authorities resorted to a wide range of activities: (a) articulating intellectual responses to the ideologies underpinning modern Middle Eastern nation-states, (b) forming political parties and other platforms of socio-political activism and (c) using various forms of cultural production by systematising and promoting Shii ritual practices and utilising visual art, poetry and new media. The project yields a perspectival shift on the factors that led to Shii communal mobilisation by: - Analysing unacknowledged intellectual responses of Shii clerical authorities to the secular or sectarian ideologies of post-colonial nation-states and to the current sectarianisation of geopolitics in the Middle East. - Emphasising the central role of diasporic networks in the Middle East and Europe in mobilising Shii communities and in influencing discourses and agendas of clerical authorities based in Iraq and Iran. - Exploring new modes of cultural production in the form of a modern Shii aesthetics articulated in ritual practices, visual art, poetry and new media and thus creating a more holistic narrative on Shii religio-political mobilisation.";1952373,99;1952373,99;ERC-2016-COG;/ERC-COG;THE UNIVERSITY OF BIRMINGHAM;UK;;;;1;0;0;1;0;0 211291;751843;POWERSHIFTS;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Shifting political power: the nature and consequences of distributed renewable energy transitions;2017-09-01;2019-08-31;;"Global energy transitions are progressing rapidly. Over half of new generation capacity in 2014 came from renewable energy. Individual, community and co-operative decentralized renewable energy (DRE) producers are capturing a growing share of energy markets (e.g. solar, wind, biomass). As their market share increases, DRE producers are becoming increasingly effective political actors. The traditional political privilege enjoyed by incumbent industries is challenged by these DRE actors as they shift control over jobs, economic growth and energy supplies. Political struggles between competing interests are increasing. However, the nature and extent of these power shifts (e.g. changes in access to policy makers, media influence), and their consequences for political systems and their outcomes (e.g. contested carbon targets, renewable energy subsidies) are poorly understood. This project addresses how and why DRE transitions are shifting political power relations, and the consequences of those shifts for political systems and outcomes. Using an interdisciplinary approach grounded in theory on sustainability transitions (i.e. Multi-Level Perspective), power (e.g. Lukes, Foucault) and institutions (i.e. institutional logics) the project will: (1) examine the conditions leading to shifts in political power by analyzing existing political power relations in regimes where DRE transitions are expected, occurring, or stalled; (2) assess the mechanisms by which political power shifts resulting from these DRE transitions are occurring; and, (3) identify the consequences of DRE-related political power shifts for political systems and their outcomes. Objectives will be explored using a global survey of 20 DRE regimes. Survey insights will be expanded in 5 international comparative cases. Findings will address urgent questions highlighted by academics, the EU, and global economic bodies about the political, economic and social impacts of the changing energy landscape.";165598,8;165598,8;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;UNIVERSITEIT UTRECHT;NL;;;;1;0;0;1;0;0 210976;741374;NOSCEMUS;SIGNED;H2020-EU.1.1.;ERC-2016-ADG;H2020;Nova Scientia. Early Modern Scientific Literature and Latin;2017-10-01;2022-09-30;;"Fundamental changes occurred in the study of nature between the late 15th and 18th centuries, leading to the emergence of modern science as we know it. This process would have been impossible without Latin as the scientific lingua franca of the era, just as today's science is hard to imagine without English. At present, this crucial role of Latin is insufficiently acknowledged, and the hundreds of thousands of scientific texts written in Latin have largely remained neglected. This severely limits the scope of research into the history of early modern science, an otherwise thriving field. The proposed project intends to decisively advance our understanding of the interrelation of Latin and science in early modern times. By applying the methods of Latin philology, yet at the same time reaching out to historians of science, it will establish early modern scientific literature in Latin as an interdisciplinary research field. This will be accomplished (a) by examining and classifying the formal variety and range of content of this literature to create an overall picture (b) by analysing its function as a medium of communication within and beyond the scientific community. To realise the first of these objectives, a tripartite database for authors, early modern texts, and secondary literature will be compiled and a sourcebook with a selection of digitally searchable texts put together, both of which will be made available online. A monograph will provide an overview structured according to the literary genres of early modern scientific literature in Latin. The second objective will be achieved through a series of interlinked monographs, whose analyses will build on the system of ancient rhetoric, the most important communicative paradigm of the early modern age. On this basis, four key functions of Latin scientific texts will be assessed: naming new phenomena; describing and explaining them; convincing others of the views expressed; and promoting science.";2421223,75;2421223,75;ERC-2016-ADG;/ERC-ADG;UNIVERSITAET INNSBRUCK;AT;LUDWIG BOLTZMANN GESELLSCHAFT GMBH;AT;;1;0;0;1;0;0 210940;726104;RELATE;SIGNED;H2020-EU.1.1.;ERC-2016-COG;H2020;Environmental Spaces and the Feel-Good Factor: Relating Subjective Wellbeing to Biodiversity;2017-10-01;2022-09-30;;"We live in a time of profound environmental change. Phenomena such as urbanisation and agricultural intensification have led to ecosystem degradation and species extinctions, and thus a reduction in biodiversity. Yet, while it is now widely asserted in the research, policy and practice arenas that interacting with nature is fundamental to human wellbeing, there is a paucity of evidence characterising how biodiversity, the living component of nature, plays a role in this accepted truth. With RELATE, I will pioneer a completely novel approach to investigating this challenging problem, innovating through interdisciplinary (human geography, environmental psychology, economics and ecology) integration and the use of both qualitative and quantitative methods. As such, RELATE will initiate a step-change in our understanding of how nature underpins human wellbeing. Three objectives will be met: (1) explore how people relate to different biodiversity attributes (particular morphologies, sounds, smells, textures, behaviours and/or cultural meanings associated with species), positively and negatively, across all classes of cultural ecosystem service and types of human-nature experience (intentional, incidental, indirect, thereness); (2) quantify variation in how people value, or not, different biodiversity attributes using a range of monetary and non-monetary valuation techniques, including new subjective wellbeing measures; (3) understand how co-occurrence between biodiversity and people may alter across space/time (both seasonal and inter-decadal), and the impact this may have on human-biodiversity relationships. The crucial trade-offs decision-makers tasked with managing environmental spaces have to make between multiple biodiversity, individual and societal deliverables cannot be optimised until we understand human-biodiversity relationships specifically. Consequently, RELATE will deliver a timely, rich and holistic evidence-base, supported by transformative science.";1953715,63;1953715,63;ERC-2016-COG;/ERC-COG;UNIVERSITY OF KENT;UK;"THE JAMES HUTTON INSTITUTE;UNIVERSITY OF LEEDS";UK;;1;0;0;1;0;0 210562;742645;BaSaR;SIGNED;H2020-EU.1.1.;ERC-2016-ADG;H2020;Beyond the Silk Road: Economic Development, Frontier Zones and Inter-Imperiality in the Afro-Eurasian World Region, 300 BCE to 300 CE;2017-09-01;2022-08-31;;"This interdisciplinary project will show that inter-imperial zones and small to mid-size regional networks of exchange were crucial for ancient Transeurasian exchange connections. It will demonstrate the significance of exchange in imperial frontier zones emerging from political, economic, infrastructural, institutional and technological development within empires. This will lead to a new conceptual frame for analyzing inter-imperiality and the morphology of exchange networks within and across imperial zones. The centuries from 300 BCE to 300 CE were a period of accelerated empire transformation involving also new regions of the Afro-Eurasian world. Consumption centres shifted, affecting production, settlement, and regional exchange networks. They changed the dynamics of exchange, created new geographies, and greater cultural convergence between imperial spheres of influence. The development of imperial frontier zones of intense exchange and mobility (e.g. Northern China, Bactria, Gandhara, Syria, and the Red Sea/Gulf/Indian Ocean coasts) was related to imperial hinterlands, their fiscal-military-administrative regimes, the development of media of exchange and infrastructures, settlement, urban growth, and so on. It was also related to new forms and levels of consumption in imperial centres. In order to understand Transeurasian connectivity, the interdependence of frontier zone and inner-imperial development is crucial. We will reveal that competitions for social power within empires mobilized and concentrated resources reclaimed from natural landscapes and subsistence economies. Greater mobility of resources, both human and material, endowed competitions for power with economic force, feeding into inter-imperial prestige economies and trade. This new model of Afro-Eurasian connectivity will abandon some problematic assumptions of Silk Road trade, while maintaining the Afro-Eurasian macro-region as a meaningful unit for cultural and economic analysis.";2498750;2498750;ERC-2016-ADG;/ERC-ADG;ALBERT-LUDWIGS-UNIVERSITAET FREIBURG;DE;;;;1;0;0;1;0;0 210812;741860;CLUNATRA;SIGNED;H2020-EU.1.1.;ERC-2016-ADG;H2020;Discovering new Catalysts in the Cluster-Nanoparticle Transition Regime;2017-09-01;2022-08-31;;"The purpose of this proposal is to establish new fundamental insight of the reactivity and thereby the catalytic activity of oxides, nitrides, phosphides and sulfides (O-, N-, P-, S- ides) in the Cluster-Nanoparticle transition regime. We will use this insight to develop new catalysts through an interactive loop involving DFT simulations, synthesis, characterization and activity testing. The overarching objective is to make new catalysts that are efficient for production of solar fuels and chemicals to facilitate the implementation of sustainable energy, e.g. electrochemical hydrogen production and reduction of CO2 and N2 through both electrochemical and thermally activated processes. Recent research has identified why there is a lack of significant progress in developing new more active catalysts. Chemical scaling-relations exist among the intermediates, making it difficult to find a reaction pathway, which provides a flat potential energy landscape - a necessity for making the reaction proceed without large losses. My hypothesis is that going away from the conventional size regime, > 2 nm, one may break such chemical scaling-relations. Non-scalable behavior means that adding an atom results in a completely different reactivity. This drastic change could be even further enhanced if the added atom is a different element than the recipient particle, providing new freedom to control the reaction pathway. The methodology will be based on setting up a specifically optimized instrument for synthesizing such mass-selected clusters/nanoparticles. Thus far, researchers have barely explored this size regime. Only a limited amount of studies has been devoted to inorganic entities of oxides and sulfides; nitrides and phosphides are completely unexplored. We will employ atomic level simulations, synthesis, characterization, and subsequently test for specific reactions. This interdisciplinary loop will result in new breakthroughs in the area of catalyst material discovery.";2500000;2500000;ERC-2016-ADG;/ERC-ADG;DANMARKS TEKNISKE UNIVERSITET;DK;;;;1;0;0;1;0;0 210479;725642;MolStrucDyn;SIGNED;H2020-EU.1.1.;ERC-2016-COG;H2020;Ultrafast Molecular Structural Dynamics;2017-06-01;2022-05-31;;"Chemical reactions in solution are strongly influenced by femtosecond solvent-solute dynamics. Likewise, proteins provide specific environments to control the outcome of substrate reactions. The molecular understanding of these effect are currently poorly developed. I propose to fill this knowledge gap by ‘filming’ elementary chemical reactions in solution and in proteins. I will pioneer new time-resolved scattering and diffraction experiments using X-ray Free Electron Lasers (XFELs). Using femtosecond time-resolved X-ray scattering, I plan to decipher the structural dynamics of bond breaking and bond formation in iodine containing compounds in solution. I will pioneer time-resolved fluctuation correlation X-ray scattering to recover full electron density maps of the reaction trajectories at an atomic resolution. I will visualize the as yet unknown structures of reaction intermediates and the solvent response. Furthermore, I propose to investigate the molecular photoresponse of phytochrome photoconversion with femtosecond time-resolved serial microcrystallography. Phytochromes are ubiquitous photosensory proteins in plants and are essential to all vegetation on earth. I will resolve how the chromophore and the protein react collectively to photoexcitation and how this leads to conformational changes. Combined, this interdisciplinary project will yield microscopic understanding on how the surrounding of reactants guides the outcome of elementary (bio)chemical reactions. This program builds on my strengths in structural biology of phytochromes (Takala et al., Nature, 2014), time-resolved X-ray scattering (Westenhoff et al., Nature Methods 2010), and femtosecond spectroscopy (21 papers in PRL, JACS, Nature Methods 2006-2012 & 2016). The new XFEL-based methods will have wide-ranging applications in chemistry and biology. My work will open new horizons in physical chemistry and structural biology.";2000000;2000000;ERC-2016-COG;/ERC-COG;GOETEBORGS UNIVERSITET;SE;;;;1;0;0;1;0;0 209562;747221;POSITS;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;High Performance Wide Bandgap and Stable Perovskite-on-Silicon Tandem Solar Cells;2017-06-01;2019-05-31;;The world is moving toward a low-carbon future. The EU Commission’s 2015 Paris climate agreement vowed to keep global average temperature to well below 2°C above pre-industrial levels and undertake rapid global emission reductions. Generation of clean energy such as photovoltaics is one of the most promising solutions. Novel organic-inorganic perovskite materials for solar cells have drawn vigorous scientific interest over the past few years due to their potential low cost, high charge carrier mobility, absorption coefficient and efficiency. The two top scientific journals, Nature and Science, selected perovskites as one of the biggest scientific breakthroughs in 2013. As perovskites are still in the early development stages, barriers need to be overcome before they can be commercialized. This interdisciplinary project draws from chemistry, physics and engineering with the aim of developing stable high bandgap mixed-cation/halide perovskite devices. Both photo- and moisture stability will be carefully studied and improved upon leading to the ultimate goal of fabricating a stable monolithic perovskite/silicon tandem solar cell with an efficiency >30%. Monolithic perovskite/silicon tandem technology has the potential to revolutionize the photovoltaics industry by greatly decreasing cost through improved efficiency making clean energy more competitive against fossil fuels. The project will be conducted at EPFL PV-Lab, a dedicated photovoltaic research centre with over 30 years of experience and close links with Swiss and European research institutes and industries. EPFL is a highly-ranked European engineering institution with world-class facilities, industrial connections and technological parks. The fellow Dr. Terry Chien-Jen Yang will be joining PV-Lab to bring unique nano-material and analytical expertise as well as collaborations from the prestigious School of Photovoltaic and Renewable Energy Engineering, UNSW in Sydney, Australia.;175419,6;175419,6;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE;CH;;;;1;0;0;1;0;0 209357;751592;WORK-CHRIST;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;The Young Christian Workers Movement and the radicalization of Social Conflict in Mediterranean Europe: France, Italy and Spain (1963-1978);2017-09-01;2019-08-31;;"'The Work-Christ project intends to reconstruct the influence of religious radicalisation on the social conflict in Mediterranean European countries, with particular attention paid to the cases in France, Spain and Italy during the sixties and seventies. The main purpose of this research is to study the relationship between religion and politics in the period following the Second Vatican Council, via the study of the 'Young Christian Workers Movement', better known by the French name Jeunesse Ouvri?re Chrétienne. This is a field of research which is totally unexplored, both regarding the interactions among the different national offshoots of the movement and the transnational reality represented by the coordinating authority of the Jeunesse Ouvri?re catholique internationale. The research will also take into account the network constituted by the Mouvement Mondial des Travailleurs Chrétiens (MMTC) to which the specialized branches of the working class Catholic Action organisations referred to. From the late sixties, the Christian workers’ associations became the terminal point of the tensions, ferment and expectations that arose from the Second Vatican Council. In addition, these associations played an essential role in the processes of transition and consolidation of democracy in the three nations taken into consideration. For these reasons, the “Young Christian Workers Movement” appears to be a case study of the utmost importance for the role played on a European scale as a workshop for the building of a radicalized young identity challenging societal norms. Work-Christ has 3 key objectives: 1. through research based on archive sources, address the innovative subject of international Christian workers’ youth associations; 2. adopt a multi-disciplinary and interdisciplinary perspective for studying religious radicalisation; 3. study the mobilisation of the Christian workers associations at transnational level, reconstructing the phases, the goals and the contents.'";173076;173076;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;FONDATION NATIONALE DES SCIENCES POLITIQUES;FR;;;;1;0;0;1;0;0 209332;750492;COMPEL;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;COsts and Mechanisms of Personalised Exercise and Education for chronic Low back pain;2018-01-08;2021-01-07;;Back pain is the leading cause of disability in Europe. Chronic low back pain (CLBP) is the most costly and burdensome form. As the EU population ages, there is an urgent need for more clinically and cost-effective therapies to ensure sustainable healthcare. Dr O’Keeffe will explore a personalised medicine approach to exercise and education for CLBP. This is cutting edge, and has shown promising results beyond other therapies. Dr O’Keeffe is the perfect match for this project, as she has led a trial on this novel therapy for her PhD. This will be the first project to examine the mechanisms, response, and the cost-effectiveness of personalised exercise and education for CLBP. This will build on Dr O’Keeffe’s experience to expand and develop her skills in this area. Dr O’Keeffe will be trained in mediation, moderation and economic evaluation. She will gain additional research skills in new study designs, research software, physical activity measurement, gender analysis and public patient involvement. She will gain transferable skills in communication and public engagement, interdisciplinary networking, grantsmanship, project management, leadership and supervision. She will gain exposure to the non-academic sector through a secondment to a non-governmental organisation. Dr O’Keeffe will disseminate her results through open-access journals and conferences. She will communicate her results and Marie Sklodowska-Curie experience through social media, TV, radio and European Research events. If awarded this fellowship, Dr O’Keeffe will be equipped with the right skillset to improve her employability and reach a position of professional maturity. She will expand the European Research Area by strengthening networks. She will put Europe at the forefront of excellence and innovation for CLBP by promoting a safe exercise and education therapy for EU citizens. This will allow billions of euro that the EU currently spends on CLBP to be redirected to other health care services.;254313;254313;H2020-MSCA-IF-2016;/MSCA-IF-GF;UNIVERSITY OF LIMERICK;IE;;;;1;0;0;1;0;0 208927;747586;ThromboForce;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Platelet tractions through the Glycoprotein (GP) GPIb receptor as a potential marker for platelet reactivity;2017-06-15;2019-06-14;;"Platelet-mediated thrombosis is a major cause of death and disability globally. Thrombosis occurs when platelets adhere and aggregate. In the arterial circulation initial platelet adhesion occurs when the platelet glycoprotein (GP) I-IX-V receptor binds to von Willebrand Factor (vWF). Increased or decreased expression levels of GPIb are associated with increased risk for cardiovascular events and bleeding respectively. The expression of GPIb varies significantly among healthy subjects. The proposed project aims to characterise the role of GPIb expression levels on traction forces and platelet reactivity. It therefore combines my significant expertise in cellular mechanobiology and traction force microscopy with theclinical expertise of Prof Dermot Kenny’s group in platelet biology and the development of diagnostic assays for platelet function. A micropost array platform for high throughput, single cell, traction force measurements will be developed and applied to understand the interaction between GPIb traction forces andplatelet reactivity, first in healthy donors and then in patients with cardiovascular disease receiving antiplatelet therapy. This platform could in the future be further exploited for examining platelet function to further understand platelet cancer interactions, and for the innovation of refined diagnostics to assess platelet reactivity in individual patients. By moving from ETH Zurich to the Royal College of Surgeons in Ireland (RCSI), this interdisciplinary and intersectoral action will allow me to gain expert knowledge on fundamental processes in vascular biology and to develop my expertise in a clinically relevant manner. The newly gained research and professional competences designed into the fellowship will greatly improve my chances of establishing a competitive independent research group in the newly founded RCSI Centre for Vascular Biology (CVB) in the near future at the interface of clinical research and biomedical diagnostics.";187866;187866;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;ROYAL COLLEGE OF SURGEONS IN IRELAND;IE;;;;1;0;0;1;0;0 208609;747381;NanoGraphInk;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Nano-Hybrid Graphene-Based Ink for Printable Flexible Transparent Applications;2017-04-01;2019-03-31;;"'Aim: Development of conductive graphene ink for printed flexible transparent applications. State-of-the-art: Advancing of printed electronics via high quality graphene inks for highly flexible displays of higher energy class and better visibility, and next generation products as wearables and transparent displays. Innovation: First graphene/carbon quantum dots (CQDs) and graphene nanobuds conductive inks. Essential study to warrant that final printed circuits demonstrate zero nanoparticles emissions. Excellence: Exploitation of graphene’s unique properties. High interdisciplinary nature linking also directly research with industry. Capacities: I have multidisciplinary background, advanced skills and extensive experience in synthesis and characterization of nanomaterials, excellent track record. Prof. Ferrari’s expertise ensures proper supervision. Cambridge possesses essential instrumentation and is excellent host institution. 'TheGrapheneBox' secures commercialization of inks. Impact: Gain skills for advanced characterization techniques as TEM, recognized as an expert in graphene inks, raise my profile by joining Cambridge, expand my network. Dealing with the hot market of printed electronics, commercialized products will find a direct industrial use. Use of foreground: Proper dissemination/exploitation of results in form of conference participations, patents, commercialized products, and publications at high impact factor journals warranted by project’s excellence. Respect to intellectual property. Follow Horizon 2020 priority for open science. Rapid communication of the outcomes by a set of measures. Implementation: Solid work plan. Use of CQDs and functionalized fullerenes for graphene’s dispersion in water. Modifiers tuning ink’s features to acquire proper rheological properties and stable colloidal suspensions. Inkjet and roll-to-roll printing employed. Films integrated in devices evaluating their applicability. Proper tasks’ allocation and mitigation actions.'";195454,8;195454,8;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;UK;;;;1;0;0;1;0;0 209615;750253;SynPCP;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Synapse formation and maturity through planar cell polarity pathway;2018-03-01;2020-02-29;;SynPCP is a MSCA-IF-EF project in Neuroscience aimed at deciphering spatiotemporal mechanisms controlled by the planar cell polarity (PCP) protein Scribble (Scrib) in spine during specification and morpho-fonctional plasticity that depend on the dynamics of the actin cytoskeleton and trans-synaptic adhesions. Growing evidences suggest that PCP signaling is fundamental for neuronal development mechanisms, including dendrite morphogenesis and synaptogenesis. PCP signaling defects have been linked to a number of human neuropathies such as autism. Because of its subcellular compartment localization and interaction with actin, we hypothesize that Scrib nanoscale organization within the spine could control cytoskeleton and/or adhesion dynamics. To address this, I plan to study the coupling or interplay between Scrib-dependent signaling and the assembly of actin cytoskeleton macromolecular complexes and its connection to cadherin-adhesion molecules using biochemistry, biophysics and 3D super-resolution optical microscopy techniques, in normal and pathological conditions. This project will provide novel conceptual insights into the nanoscale segregation of PCP proteins in spines and how individual PCP proteins control the actin cytoskeleton to build functional synapses. This project will offer a multilevel and interdisciplinary approach to understand the consequences of mutations of PCP signaling at the nanoscale, cellular and physiological levels, on the establishment, maturation and function of the basic functional unit of neuronal integration in the complex circuit of the hippocampus: the dendritic spine. SynPCP will be setup at the Bordeaux Neurocampus which is well known for its contribution to synapse development and brain function. This project offers a scientific and training program critical for my career but also for the general understanding of the molecular mechanisms underlying the normal and pathological brain.;173076;173076;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE;FR;;;;1;0;0;1;0;0 209581;748369;SAVE;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Shear Stress Induced Arterial and Venous Specification through Piezo1;2018-07-01;2020-06-30;;"Arteriovenous malformations (AVMs) are characterised by abnormal connections between arteries and veins due to defects during vascular remodelling. Although often asymptomatic, AVMs can cause intense pain and patients affected present higher risk for strokes and aneurysms. Hereditary AVMs have a prevalence of 18 in 100000 people causing a two-fold increase in mortality in patients younger than 60 years of age. Hereditary AVMs are linked to defective Notch/BMP signalling, however they represent less than 10% of cases. The majority of AVMs do not present genetic mutations and remain idiopathic. Asides Notch/BMP signalling, vascular responses to haemodynamic forces generated by blood flow are crucial regulators of blood vessel formation. The passage of fluid results in physical forces on the endothelium, i.e. shear stress, which activate signalling cascades inside the cells necessary for vascular remodelling. Endothelial cells sense shear stress through proteins localised on their plasmatic membrane. The calcium channel Piezo1 is required for shear stress induced calcium signalling and its ablation resulted in serious vascular defects. Both shear stress and calcium signalling are known to affect the activation of Notch, a pathway essential during the process of arterial-venous specification and vascular remodelling. Therefore we hypothesise that Piezo1 plays a crucial role in arterial venous specification and onset of AVMs by modulating Notch signalling activation. This proposal utilises an interdisciplinary approach to decipher the new targets underlying the intricate and still unknown interaction of physical and molecular mechanisms responsible for defective arterial venous specification. The results of this research will potentially provide appealing diagnostic and therapeutic opportunities for both hereditary and idiopathic AVMs.";195454,8;195454,8;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;UNIVERSITY OF LEEDS;UK;;;;1;0;0;1;0;0 209547;746363;ChildEmp;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Understanding children's empathy: an ethnographic study among the indigenous Runa of the Ecuadorian Amazon;2018-01-12;2020-01-11;;"The phenomenon of empathy is receiving growing interest in the European public sphere and scientific community. In particular, the question of how one learns to feel empathy towards the environment and the beings which inhabit it has been identified as a key issue to address at this time of environmental crisis.The proposed project investigates how empathy is learnt by children from an Amazonian indigenous community in Ecuador. It explores how and under what circumstances indigenous children in the Ecuadorian Amazon learn to perceive nonhuman entities as human-like and develop empathy towards them. Grounded upon my extended ethnographic knowledge of the region, the project will contribute to broader contemporary debates of how empathy towards nonhumans is culturally acquired, manifested and actively learnt during childhood. This is a social anthropology project with a strong interdisciplinary approach which includes perspectives from developmental psychology, ecology, cognitive science and philosophy. The aims of this project are: 1. to explore how children learn to perceive others as human-like in a setting which is inductive to such learning; 2. to explore children’s perception and understanding of nonhuman personhood and intentionality; 3. to understand the nature of ‘empathy’ among indigenous Runa people of the Ecuadorian Amazon. These aims will be reached through 10 months of ethnographic fieldwork in an indigenous Runa village where I will deploy participant observation and other methodologies from psychology, medical and visual anthropology which will be designed during pre-fieldwork training at the University of Kent. Research results will be disseminated through an academic and public engagement plan which includes two academic publications, an ethnographic film, a secondment at the Centre for Subjectivity Research in Copenhagen, a workshop and a document to be used by community members for school policy-making.";195454,8;195454,8;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;UNIVERSITY OF KENT;UK;;;;1;0;0;1;0;0 209081;753893;MetaBiota;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Crosstalk between microbiota metabolites and immune cells, the missing link to brain damage.;2017-05-01;2019-04-30;;"Stroke is the second most common cause of death in Europe: accounting for almost 1.1 million deaths each year, with only 15% of stroke patients being eligible for a specific treatment. I have reported–in this year Nature Medicine’s April issue–that microbiota influences the severity of stroke injury through an impaired intestinal immune function. These findings revealed for the first time the critical implication of the microbiota as a novel and relevant prospective target for therapeutic strategies in stroke. However, the development of efficient therapies requires to identify which bacterial species and bacterial products are involved in the modulation of the immune response and thereby influence stroke outcome. To fill in this knowledge gap, my proposal aims to identify how metabolites derived from gut bacteria modulate the intestinal immune response and thereby influence the brain in the setting of stroke. To investigate this novel paradigm, I will use cutting-edge metabolomic tools to precisely analyze a large panel of metabolites, high-throughput sequencing to identify bacterial species, specific knock-out mice and mouse models of altered-microbiota available at the host institution and its established collaboration partners. This is the first attempt to discover a relationship between microbial metabolites, immune cell regulation and severity of ischemic stroke. Information derived from this project will have the potential to enable development of a “neuroprotective” microbiota–by diet intervention–and reduce the dramatic consequences of stroke. The Marie Sklodowska-Curie individual fellowship (MSC IF) will allow me to obtain the required methodological knowledge, access to critical infrastructure and collaboration partners in order to achieve this interdisciplinary and ambitious objective. My overall goal will be to gain this training fellowship to become an independent investigator and a leader in the field of stroke and microbiota biology.";159460,8;159460,8;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN;DE;;;;1;0;0;1;0;0 209080;753565;Sounds Delicious;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Sounds Delicious: A historical anthropology of listening and sound in Danish and French cooking;2018-09-01;2020-08-31;;The Sounds Delicious project investigates how sound and listening function in different culinary traditions in Denmark and France. The project aims to construct a new interdisciplinary dialogue between Sound Studies and Food Studies that will enrich how we study everyday cooking processes and the gustatory. This study questions how we construct cultural histories of cooking. I suggest that dominant research paradigms based on alphanumeric and visual epistemic practices (words, images, measurements) are insufficient for fully understanding the particular components and choreography of a cook’s practice—and what cooking relates about personal histories and larger social and cultural tendencies. In adopting an aural perspective of the kitchen, I engage alternative methods of perceiving evidence, and I revisit approaches of documentation, analysis and communication of the everyday. In this project sound and sonic practices are both research object and research method—both matter and medium. Sound is used to trace, analyse, even reenact different performances of cooking. I will establish a new corpus of examples documenting sound and aural perception in Danish and French kitchens between the 19th and 21st centuries. In working with a varied set of historical and anthropological tools, I will not only identify sounds in cooking, but introduce performances of cooking in relation to other histories of sonic and sensory knowing.;200194,8;200194,8;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;KOBENHAVNS UNIVERSITET;DK;;;;1;0;0;1;0;0 209076;753272;CC4M;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Innovation through co-creation in contemporary mining relations: a new paradigm for stakeholder engagement at resource extraction project;2017-08-07;2020-08-06;;This research project and training programme explore the contemporary practice and future potential of co-creation models in stakeholder engagement, and seek to define a new paradigm and design a new model for sustainable resource relations in the mining industry. The call will generate cooperation between University of Queensland’s Centre for Social Responsibility in Mining, a globally recognised hub of innovation and research excellence into resource relations, and University of St Andrews’ Centre for Pacific Studies, one of Europe’s leading research institutions with focus on the Pacific and, responding to the need for European expertise, will create new sites for European innovation and action in the crucially important context of resource relations. The proposed research project will use an interdisciplinary toolkit of research methods capable of reaching and engaging comprehensively with a wide spectrum of corporate, indigenous and increasingly influential ‘virtual’ stakeholders at mining projects in Papua New Guinea, uniquely mediating the nexus of resource host, industry and academy and moving beyond the dominant paradigm in resource relations. It will disrupt a series of well-established preconceptions about the nature of relations between stakeholders in resource contexts, identify new spaces for industry innovation, and propose new, more responsible and sustainable solutions to stakeholder engagement at mining projects. This project carries real potential to influence corporate and industry policies and actions, contributing to successful agreement making and Sustainable Development outcomes in resource relations.;276107,4;276107,4;H2020-MSCA-IF-2016;/MSCA-IF-GF;THE UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS;UK;;;;1;0;0;1;0;0 209204;745776;PHOTOPEROVSKITES;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Photoexcitation Dynamics and Direct Monitoring of Photovoltaic Processes of Solid-State Hybrid Organic-Inorganic Perovskite Solar Cells;2017-09-01;2020-02-29;;"Abundant, cheap and clean source of energy is fundamental to preserve global environment and sustained economic growth. Solar energy is considered as the ultimate solution in this regard. Among the three generations of solar cells developed with this objective, hybrid organic-inorganic perovskite solar cells with demonstrated power conversion efficiency (PCE) of over 22 % have bagged the greatest attention. Despite the impressive PCE, lower cost and facile processing opportunities for hybrid perovskite solar cells, their commercialization is not yet realized; poor stability, lack of robustness to subtle variations in processing, and Pb toxicity being the bottlenecks. We take up the view that pursuing fundamental understanding of the photophysics and photovoltaic process of these highly efficient lead halide perovskites can contribute to tackle their instability issue and also to the development of Pb free organic-inorganic halide perovskites with analogous optical and photovoltaic performance to that of former, expediting their market entry. Apart from photovoltaic sector, the fundamental knowledge evolved through this project is expected to have direct impact on the fabrication of high performing photodetectors, lasers, and light emitting devices based on hybrid perovskite materials. This interdisciplinary project lying at the interface of material science, physics and chemistry is expected to bring a breakthrough in perovskite solar cell research arena.The proposed project will utilize the applicant’s expertise in the fabrication of high efficient organic and perovskite solar cells in combination with world leading scientist Prof. Ifor Samuel’s expertise on photophysics aspects of thin film solar cells and the excellent infrastructure facilities at the host institution. In implementing this ambitious project, I will gain expertise on the photophysics and photovoltaic processes (under real operating conditions) of hybrid perovskite thin films and solar cells.";195454,8;195454,8;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;THE UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS;UK;;;;1;0;0;1;0;0 209270;748106;TOOLBOX;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Treatment of contaminated land using a biochar/media mixture;2017-07-10;2019-07-09;;"Waste disposal and treatment is a major source of contamination of soils, surface and groundwater, and accounts for 35% of the 1.1 million contaminated sites in Europe. Leaching of the organic solvent trichloroethylene (TCE) into groundwater has been identified as a primary issue with unlined landfills , affecting up to 70% of leachates tested. Mainly used as a metal degreaser and dry-cleaning reagent, TCE is difficult to treat; current treatment methods, such as anaerobic digestion or air stripping , are ineffective and/or expensive. This project will investigate the use biochar, or other appropriate media, for treatment of TCE contaminated water via two technologies - permeable reactive interceptors (PRIs) and permeable contaminant retaining filter (PCRF) bags. This novel, low-cost solution will address the requirements of European Union (EU) legislation, including the Water Framework Directive (WFD). The project will be based at the National University of Ireland, Galway (NUIG) with supervision by Dr Mark Healy (GeoEnvironmental Engineering Research Group – GENE) and support from Dr Florence Abram (Functional Environmental Microbiology - FEM). As the applicant has experience in TCE treatment from a microbial background, this highly novel, interdisciplinary proposal will compliment and strengthen her existing skillset by approaching this technology from an engineering perspective, with support from a research group that has a strong track record in this research area. With detailed career development assistance, multiple opportunities to further her strong publication record, access to numerous and varied fora for dissemination of results and support for IP exploitation, this proposal will have a significant impact in reintegrating the applicant back into the EU research community from her current research position in New Zealand.";187866;187866;H2020-MSCA-IF-2016;/MSCA-IF-EF-RI;NATIONAL UNIVERSITY OF IRELAND GALWAY;IE;;;;1;0;0;1;0;0 208564;745584;INSPIrE;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Intellectuals in History: Political Process and Cultural Impacts in Medieval Europe (14th and 15th centuries);2017-04-01;2019-03-31;;"The principal aim of INSPIrE is to create a picture of the relationship between politics and written culture in 14th and 15th century Europe, focusing on the Franco-German and Italian geographical areas. INSPIrE will answer several questions which have arisen regarding the link between intellectual production and major historical events, such as: which are the most relevant historical events for written culture? Can a philosophical treatise influence politics? How many women write political texts? The project aims to identify the development lines, breaking points, peculiar cases and matching patterns of the relationship between politics and written culture, reckoning with five key features: the combination of events, places, times, languages, gender and literary genres will allow us to map the networks of texts linked to historical events. In the first phase, data concerning texts linked to the historical events selected as relevant - four case studies are planned - will be gathered and arranged according to the five key features. In the second phase of the research, the analysis of collected and arranged data will produce the expected results. The bottom-up methodology, based only on concrete data, the synchronic and diachronic approach and the text/context connection are the most innovative elements of INSPIrE. The project represents an excellent topic for Medieval Studies and also constitutes a ground-breaking chance to fill the gap between past and present, since it clarifies the roots and history of the connection between politics and culture in Europe. Moreover INSPIrE addresses the guidelines of the Horizon 2020 Work programme 2016-2017: the project will promote interdisciplinary cross-fertilization to overtake the separation among SSH disciplines and better understand historical and cultural phenomena. INSPIrE will also use an innovative approach to research training, with special focus on the gender dimension in research contents.";185076;185076;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;UNIVERSITE DE STRASBOURG;FR;;;;1;0;0;1;0;0 209534;745947;Starflict;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Conflicts in start-ups: coping with stress and conflicts to promote well-being and entrepreneurial success;2018-02-08;2020-02-07;;"Start-ups are Europe’s 2020 Priorities for strengthening economic growth. However, about 50% of new European businesses fail during their first five years, conflicts between founders and effects of work stress being two of the top reasons for failure. However, conflicts and stress in start-ups, as well as factors for their entrepreneurial success are under-studied. The aim of STARFLICT is to elaborate a typology of conflicts in start-ups, develop an assessment tool for conflicts in start-ups, identify the early indicators of start-ups’ entrepreneurial success in terms of individual- and group-level coping, and offer practical guidelines for start-ups on how to effectively deal with conflicts and stress using individual and group-level coping strategies. This will allow to take preventive actions to avoid destructive spirals of conflicts and stress that lead to start-up’s failure, ensuring start-up’s entrepreneurial success and their founders’ WB, while increasing start-ups’ success rate. The objectives of STARFLICT will be achieved using new and powerful techniques for data collection (IT-supported diary, actigraphy) and cutting-edge data analysis methods (Latent Growth Curve Modeling, Multilevel Structural Equation Modeling) that allow for obtaining fine-grained high quality (hard) data and modeling dynamics. STARFLICT’s objectives are relevant to the work program because they are innovative, interdisciplinary, address a timely issue of start-ups’ entrepreneurial success, and considerate the gender issues. STARFLICT’s plan of work includes bi-directional transfer between myself and KU Leuven. KU Leuven will provide me with resources, specific training in advanced methodology, and with an excellent stimulating scientific environment. STARFLICT will clearly enhance my future career prospects and allow me undertake higher risk research in the future that, in turn, will have an impact on the European science-based knowledge.";160800;160800;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;KATHOLIEKE UNIVERSITEIT LEUVEN;BE;;;;1;0;0;1;0;0 209629;751131;Road Diplomacy;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Road Diplomacy: International Infrastructure and Ethnography of Geopolitics in 21st Century Asia;2018-06-01;2020-05-31;;The objective of this project is to understand where, why, and to what extent roads are being built between China and South Asia and to untangle the inter-related geopolitical and social impacts of infrastructure development at village, national, and international scales. The project will first map road developments throughout the trans-Himalaya and second investigate the geopolitical drivers and social impacts of road construction. By combining innovative methods from geography, anthropology, and international relations, I will produce new empirical data on infrastructure development in 21st century Asia and illustrate the links between macro geopolitical processes and micro local experiences. Datasets will improve interdisciplinary communications for social scientists and between development practitioners, donor agencies, policymakers, and local stakeholders. The research is of relevance to EU citizens because understanding contemporary dynamics between rising powers like China and India provides context on 21st century global politics and will inform decision-making for EU investment and development interventions in Asia.;171460,8;171460,8;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN;DE;;;;1;0;0;1;0;0 209176;740481;PIONEER;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;The effect of seagrass bed habitat quality on selected ecosystem services;2018-01-08;2020-01-07;;"Seagrass meadows serve many important ecosystem functions and services in coastal waters. Most notably, through their role as nursery and feeding areas they support a great abundance and diversity of fish and invertebrates, making them important for fisheries and local economies. In spite of their ecological and socio-economic importance, seagrass meadows worldwide have been experiencing declines and habitat degradation through fundamental changes in their structural complexity. Currently only limited knowledge exists of how these configurational changes influence the functioning and the ecological and cultural services provided by seagrasses. Through a combination of ecological and social data collection methods that include citizen science, PIONEER takes an interdisciplinary approach to assess how changes in the environmental status of Posidonia oceanica ecosystems affect important ecosystem services for both marine biota and humans in the Balearic Islands, namely (i) seagrass nursery function for juvenile fish, (ii) food provision capacity for adult fish and fishers’ perception of the recreational fishing sector. PIONEER provides relevant and timely information for the implementation of the EU Marine Strategy Framework Directive, which aims to achieve Good Environmental Status in all water bodies across EU member states by 2020. Findings from this project will be relevant for both conservation and management of these habitats; dissemination of results will target scientists, governmental and non-governmental authorities and end-users of seagrass habitats. The fellowship contributes to the candidate’s career development mainly through the acquisition of advanced skills in ecological and social sciences that will provide a notable improvement to her multidisciplinary background and diversification of research expertise, as well as enlarging the international network of professional contacts to southern Europe.";158121,6;158121,6;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS;ES;;;;1;0;0;1;0;0 209783;748344;SYRMAGINE;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Syrian Imaginations of Europe;2017-09-01;2019-08-31;;"Refugees’ attempts to flee to a certain country are usually preceded by imaginations about possible destination countries. These imaginations not only contribute to refugees’ decisions where to seek asylum but also have an effect on how refugees experience realities when they eventually arrive in the destination country. The research project ‘SYRMAGINE – Syrian Imaginations of Europe’ focusses on how Europe is imagined by Syrian refugees settling in Syria’s neighbouring countries and examines how refugees’ imaginations affect their attitudes to seek asylum in European countries. SYRMAGINE understands “geographical imaginations” of Europe as subjective human conceptions of a geographical location and stresses the differences between “imagined regions” and reality. The project adopts an interdisciplinary mixed-method approach combining a large sample of individual surveys, semi-directive interviews and an online ethnography in two recipient and transit countries of Syrian refugees in the Middle East, Lebanon and Turkey. SYRMAGINE contributes to the academic literature on the active role of imaginations in refugees’ decision-making. From a policy perspective, it responds to one of the key priorities of the Horizon 2020 work programme 2016-2017, which is to investigate the governance of migration and asylum. The research is highly time relevant due to the surge of Syrian asylum application in Europe in the last years: Between April 2011 and June 2016, more than one million Syrians have applied for asylum in Europe (UNHCR 2016). The research project has the following three objectives: 1) to investigate the relation between refugees’ imaginations and decision-making and to study how the present country of residence compares to Europe as a destination choice, 2) to examine how refugees inform themselves about social and political realities in European countries and 3) to use these findings to contribute to the development of evidence-based asylum and integration policies.";165598,8;165598,8;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;UNIVERSITEIT VAN AMSTERDAM;NL;;;;1;0;0;1;0;0 209537;746060;CHIRALQUBIT;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Antiferromagnetic spin-chiral triangles as decoherence-free qubits;2017-04-01;2019-03-31;;"Quantum Information Processing (QIP) is a groundbreaking new field with implications ranging from overcoming Moore's law to the security of encrypted communications. As such it has been identified as a priority by the European Commission. With several theoretical concepts having been clearly defined, and with quantum limits to Moore's law approaching, it is now important to find materials that will allow the physical implementations of qubits, the principal components for QIP. Molecular Nanomagnets (MNMs) are promising such materials which, however, exhibit short quantum decoherence times. CHIRALQUBIT identifies a new quantum property of MNMs, spin chirality, as a means to overcome this limitation and achieve decoherence-free qubits, with the added advantage of their rapid and precise electric manipulation. The project’s objectives are to confirm for the first time the electric control of spin-chiral coordination complexes, in particular antiferromagnetic triangles of half-integer spins, and study their relaxation and decoherence dynamics regarding transitions reversing their spin chiralities. The proposed research employs diverse methodologies from synthetic chemistry and spectroscopy to instrumentation and theory. Through the expertise of the host it will achieve the highly interdisciplinary training of an outstanding candidate in fields such as Electron Paramegnetic Resonance (EPR) spectroscopy and QIP, while also preparing him for an independent career through training in research management, mentoring, and proposal writing. Moreover, with its proposed outreach actions it will bring this new field closer to non-specialist and younger audiences. The unique combination of expertise of the host group and of the candidate and the highly innovative nature of the project, makes the present proposal a key opportunity for the advancement of the applicant's career as a mature researcher in the fields of Molecular Magnetism, EPR spectroscopy and QIP.";185076;185076;H2020-MSCA-IF-2016;/MSCA-IF-EF-RI;UNIVERSITE DE STRASBOURG;FR;;;;1;0;0;1;0;0 209339;750690;GASAC;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Gender Aspects of Screen Adaptations of the British Nineteenth-Century Female Literary Canon;2017-10-02;2019-10-01;;"The aim of the project is to analyse the gender aspects of British and American screen adaptations of selected nineteenth century women’s novels. As the contemporary popular culture is increasingly reliant on adaptation and other derivative types of cultural texts such as sequels, retellings, and pastiche, it becomes vital to study the continued appeal of canonical literature. The project aims to study screen adaptations released between 1990 and 2010, which are internationally known and became parts of the shared collective cultural experience, influencing the popular perception of European nineteenth-century culture and the position of women within that culture. The project will consist of four components: (1) studying the adaptation authors’ (directors, screen writers etc.) stated motivations and perceptions of the original writers, revealed in interviews, DVD commentaries and other ancillary materials; (2) analysing the nature of “novel to film” changes, with special attention to the portrayal of female characters and the issues of women’s agency and empowerment; (3) studying the role of the visual elements, e.g. costumes, scenography, cinematography and editing in the portrayal of female characters (4) analysing the receptions of adaptations and studying the possible “film to novel” transmission. The proposed research project is highly interdisciplinary in nature, aiming to use in a complementary way the perspectives of adaptation studies, gender studies and reception studies and film studies. It is based on solid theoretical founations (understanding he nature of the transmedial shift), but also involves a case-study approach to the chosen novel-and-adaptations clusters. Its expected impact is to offer a comprehensive analysis of the issues of women’s agency and empowerment in the selected adaptations and to study the influence of these adaptations on the audiences' perception of the nineteenth-century culture.";173857,2;173857,2;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;LINNEUNIVERSITETET;SE;;;;1;0;0;1;0;0 209585;748647;EVACUATION;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Testing communication strategies to save lives in emergency evacuation;2018-03-01;2020-02-29;;"The EU urgently seeks to improve emergency evacuation preparedness. EU public spaces are getting more crowded. Fires and terrorist attacks require emergency evacuation. Faster evacuation from public buildings during emergencies saves more lives. Observations of actual emergencies show that people tend to be slow to respond to evacuation alarms (taking up to 10 minutes) and take the familiar route out instead of the nearest exit. The EU calls for evidence-based recommendations for evacuations, which are mostly non-existent. The state of the art uses computer models of evacuation speed, but more realism is needed. We take the novel approach of combining state of the art computer modeling with insights from risk communication to improve speed and survival in emergency evacuations. This project aims to: 1. Identify which risky behaviors occur in emergency evacuations and underlying causes (WP1). 2. Use models to identify communication strategies that improve evacuation time and survival (WP2). 3. Test communication strategies for improving evacuation time and survival in experiments (WP3). To ultimately save lives, Aim 1 involves (a) observing behavior in existing videos of actual evacuations, and (b) interviewing emergency service members about their experiences in actual evacuations. Aim 2 will use ‘agent-based’ computer modeling, with which the Fellow has experience, to assess the effect of reducing the riskiest behaviors on evacuation time and survival rates. Based on the Supervisor’s expertise in risk communication and input from emergency service members, this will result in recommendations that will be tested in Aim 3 in actual evacuation drills. Our unique team has the interdisciplinary and practical expertise needed to improve evacuations. Our proposed work will promote transfer between the Fellow and the team through hands-on collaborative work. The UK is an ideal testbed for our project aims, but we will inform evacuations worldwide.";195454,8;195454,8;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;UNIVERSITY OF LEEDS;UK;;;;1;0;0;1;0;0 209685;753750;RaSiR;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Rule-algebraic Simple Rewriting;2017-10-01;2019-09-30;;The basis for this project consists in a mathematical framework previously developed by the applicant that allows to describe graph rewriting systems algebraically, the so-called rule algebraic framework. In order to advance and valorise the concept, this project proposes to develop a general concept for rule-algebraic simple rewriting (RaSiR), both for conventional graph rewriting and for a novel form of simplicial rewriting. Secondly, RaSiR will serve as the basis for developing rule-algebraic variants of trace compression and observable-update algorithms for the rewriting system Kappa. The final aim of the project consists in developing and implementing the so-called observable-centric bootstrapping algorithm (OCBA) as a module for the simulation suite KaSim for the Kappa language. Kappa is predominantly used for simulating biochemical reaction systems, which typically display an extremely high combinatorial complexity. The algorithms and software modules developed in this project will provide in particular an alternative to pure stochastic simulation via the SSA algorithm as currently implemented in KaSim, in the form of the OCBA module. This module will admit the generation of approximate observable distributions from individual pure states of the system by calculating algebraically truncations of the formal solution of the chemical master equation as well as the induced observable update functions. The project shall be hosted by Dr. Jean Krivine of the PPS team at IRIF at the University Paris-Diderot in France. Dr. Krivine is one of the two main developers of the KaSim simulation suite, and moreover one of the world experts in the theoretical and practical development of the programming language Kappa. IRIF will provide an ideal environment for the applicant to develop new skills, to be part the very interdisciplinary research team PPS, and to communicate and valorise the project results to the greater biochemical and systems biological simulation community.;173076;173076;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;UNIVERSITE PARIS DIDEROT - PARIS 7;FR;;;;1;0;0;1;0;0 209351;751175;SmartMOFs;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Smart Metal Organic Frameworks for Sensing Volatile Organic Compounds;2017-06-01;2019-05-31;;SmartMOFs targets a new generation of Metal Organic Frameworks (MOFs) for sensing harmful volatile organic compounds (VOCs). The innovation of SmartMOFs is based on a combined sensing approach, where both optical and electrical changes in the MOF material enable the recognition event. The primary step to meet the required combination of specific absorption/emission and conductivity properties is the selection of the MOF structural units, supported by theoretical investigations. The selected units will offer extensive connectivity, flexibility, tunable porosity and functionalization of the inner surface of the network, with groups interacting with the analytes by means of coordination bonds, p-p interactions or hydrogen bonds. Harmful volatile compounds will entail gases and solvents (e.g., alcohols, benzene, hexane, cyclohexane). The SmarMOFs sensors will show increased selectivity and sensitivity with respect to the state-of-the-art. Deposition of the new MOF materials on surfaces to create sensor devices will be accomplished by advanced deposition techniques. SmartMOFs will thus overtake the current bottleneck of processability that limits practical applications of these materials, filling the gap between basic research and marketable applications. The high interdisciplinarity of SmartMOFs and its foreseen applications in the highly relevant area of public health will be a springboard for the Experienced Researcher to start a successful career in the academic or industrial sectors.;180277,2;180277,2;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;CONSIGLIO NAZIONALE DELLE RICERCHE;IT;;;;1;0;0;1;0;0 210049;741413;HOPE;SIGNED;H2020-EU.1.1.;ERC-2016-ADG;H2020;Humans On Planet Earth - Long-term impacts on biosphere dynamics;2018-01-01;2022-12-31;;"A critical question in Earth system science is what was the impact of prehistoric people on the biosphere and climate? There is much information about human impact through clearance, agriculture, erosion, and modifying water and nutrient budgets. Humans have greatly changed the Earth in the last 8000 years, but did humans modify the major ecological processes (e.g. assembly rules) that shape community assembly and dynamics? Did inter-relationships between processes change in response to human impact? Lyons et al. & Dietl (2016 Nature) suggest that human activities in the last 6000 years had such impacts. Dietl proposes that using past ‘natural experiments’ to predict future changes is “flawed” and “out is the use of uniformitarianism”. As using natural experiments is a common strategy and uniformitarianism is the major working concept in Earth sciences, it is imperative to test whether prehistoric human activity changed major ecological processes determining community development. To test this hypothesis, patterns in pollen-stratigraphical data for the past 11,500 years from over 2000 sites across the globe will be explored consistently using numerical techniques to discern changes in 25 ecosystem properties (richness, evenness, and diversity; turnover; rates of change; taxon co-occurrences, etc.). Patterns in these properties will be compared statistically at sites within biomes, between biomes, within continents, and between continents to test the hypotheses that prehistoric human activities changed the basic ecological processes of community assembly and that their inter-relationships changed through time. These areas provide major contrasts in human prehistory and biomes. HOPE is interdisciplinary: pollen analysis, databases, multivariate analysis, ecology, new statistical methods, numerical simulations, statistical modelling. HOPE’s impact goes beyond human effects on the biosphere and extends to the very core of Earth science’s basic conceptual framework.";2278884;2278884;ERC-2016-ADG;/ERC-ADG;UNIVERSITETET I BERGEN;NO;;;;1;0;0;1;0;0 209587;748770;GenHumChild;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Gender and transnational Humanitarian Commitment for Children (Europe - 1980-2007);2017-09-04;2019-09-03;;"The main objective of this project is to examine the extent to which “gender”, as category of analysis, can be a useful tool in explaining the nature and the impact of humanitarian aid of western organizations towards children in Europe, between 1980 and 2007, using as case study the relation France (initiator)-Romania (beneficiary). The main objectives are: to identify all the stakeholders involved in the humanitarian aid for children, the targeted problems, if the large framework of intervention to see if formally it addressed these gender particularities; to describe the grassroots activity and the human resources of the humanitarian organisations involved in aiding the children, with a special focus on the motivation(s) that stood behind both the personal and institutional involvement and of there any differences between women and men; a survey on the local impact of each of the major intervention axes, insisting on sensitive issues, such as the accusations of paedophilia and the scandal surrounding international adoptions. This project is at the crossroad of four highly interdisciplinary research areas: Humanitarian aid, gender studies, childhood studies and European Studies and, accordingly, uses specific methodological approaches. The research will benefit from the extensive use of archives and oral testimonies from those that were directly part both of the process of decision, sources that are presently insufficient or unexplored. The research challenges the monolith unity of the Eastern Bloc. By studying the institutional, personal and conceptual relationships, the fellow wants to confront this statement with sources that have not yet been exploited. It will highlight the complexity of transnational humanitarianism towards children, with its undeniable benefits but also the questionable aspects, such as human traffic. This research intends to deliver a “Good Practice Guide” on humanitarian actions towards children Short summary should be given here.";185076;185076;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;UNIVERSITE D'ANGERS;FR;;;;1;0;0;1;0;0 208573;745770;SANDFECH;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Micromechanics-based finite element modeling of sandwich structures;2017-08-23;2020-08-22;;"The use of novel steel sandwich panels in ship decks instead of conventional stiffened plates offers more economical and energy-efficient designs through material, space and fuel savings. To analyse the global structural response of a large ship within computational limits, the sandwich panels need to be modeled in an averaged (homogenized) sense without accounting for every small detail. Motivated by this, my objective is to develop simplified theoretical and computational micromechanics-based beam and plate models for sandwich panels that have unidirectional structural cores and flexible joints. The key theoretical modeling idea is to consider periodic panels as discrete lattices which are replaced by energetically equivalent, linear micropolar continuum beam and plate models. Subsequently, finite element models for the substitute-continuum beams and plates are formulated. Contrary to existing methods, the proposed approach includes all the necessary features. First, it fully accounts for flexible (e.g. laser-welded) joints of the panels. Second, the determination of all model parameters is straightforward. Third, the derived models can be easily implemented later in various readily available finite element software. In addition to shipbuilding, structural core sandwich panels have applications in bridge engineering and residential buildings. The micromechanical aspect of this project is expected to provide new understanding of interdisciplinary issues in higher-order continuum theories. Such theories form a central topic in my host’s, Prof. J.N. Reddy’s research group at Texas A&M University in addition to beam and plate theories and finite elements. The results of this project are disseminated in workshops to shipbuilders at Meyer Turku shipyard (Finland) and to bridge researchers at Chalmers University of Technology (Sweden) during the return phase in the Advanced Marine Structures research group at Aalto University, Finland.";249793,2;249793,2;H2020-MSCA-IF-2016;/MSCA-IF-GF;AALTO KORKEAKOULUSAATIO SR;FI;;;;1;0;0;1;0;0 210244;741251;ELECTRA;SIGNED;H2020-EU.1.1.;ERC-2016-ADG;H2020;Electrochemically induced Asymmetry: from materials to molecules and back;2017-09-01;2022-08-31;;"Asymmetry is a very common feature of many systems, objects and molecules, that we use in our daily life. Actually, it is in a majority of cases the absolutely crucial ingredient for conferring a useful property to a system, a prominent example being the chiral nature of pharmaceutically active compounds. Chemists have developed various approaches to generate asymmetry, from the molecular to the macroscopic scale, but are still facing major challenges when exploring efficient alternative physico-chemical concepts for symmetry breaking. The global aim of ELECTRA is to propose so far unexplored and versatile strategies, based on the unconventional use of electrochemical phenomena, to generate asymmetry in chemical systems at different length scales. Investigating simultaneously wired and wireless electrochemistry will open up unique possibilities for advancing the topic of asymmetry generation in an original and cross-disciplinary way. We will determine the utility of these strategies in the frame of two major challenges that are: -unconventional detection, separation and synthesis of enantiomers, based on chiral encoded metal phases, very recently pioneered by us; -design and characterization of Janus systems with complex structures and reactivity Carefully designed experiments at the forefront of electrochemical science will first enable us to gain a better understanding of the different mechanisms involved in symmetry breaking. An optimization by exploring new concepts with respect to their efficiency, yield and selectivity is the next step. This will prepare for the choice of the most innovative approaches of symmetry breaking, in view of the numerous highly relevant applications, ranging from analysis to catalysis and energy conversion. Furthermore, due to the interdisciplinary character of asymmetry, the findings of this project will not only have a major impact in various areas of chemistry, but will also be very interesting for physics and biology.";2415848,75;2415848,75;ERC-2016-ADG;/ERC-ADG;INSTITUT POLYTECHNIQUE DE BORDEAUX;FR;;;;1;0;0;1;0;0 209841;753100;Neuronal MRI;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Neuronal MRI: Harnessing chemical exchange between N-Acetylaspartate and water for functional imaging of neural activity;2017-05-01;2019-04-30;;"Functional MRI (fMRI) is currently the leading noninvasive modality to assess brain function in vivo. However, it relies on a surrogate marker for neural activity –the hemodynamic responses following activity– which makes fMRI nonspecific and difficult to interpret. Here, we propose to advance the state-of-the-art by developing and evaluating a methodology we term neuronal fMRI (nMRI) which would enable a direct measurement of neuronal activity and its fast dynamics. Achieving this arduous goal calls for a truly interdisciplinary effort, borrowing concepts from Chemistry (Chemical Exchange Saturation Transfer (CEST) of a neuronal-selective metabolite to impart specificity, restricted diffusion to probe cell sizes), Physics and Engineering (advanced MRI and reconstruction methods). Our general approach consists of a development-validation-application design, thus our main objectives are: 1. Harnessing the hitherto unexplored downfield resonance of N-Acetylaspartate (NAA) –a metabolite confined solely to neurons– in CEST MRI experiments, thus imparting specificity towards the neuronal population; combining this specificity enhancement with diffusion MRI sequences that are extraordinarily sensitive to cellular sizes, and hence are able to sense subtle cell-swellings arising upon neuronal firing. This new method, which we term neuronal-MRI (nMRI) will thus report on neuronal swellings, and as such reflect activity directly. 2. Implementing ultra-fast imaging techniques based on data multiplexing and the latest compressed sensing frameworks to nMRI, such that the 50 ms timescale can be reached with full brain coverage. This will allow the measurement of fast neuronal activity dynamics in the brain. 3. Applying nMRI to study the auditory circuit as a model system in-vivo. In summary, we posit that nMRI –upon successful implementation and rigorous testing– will be highly impactful in many disciplines, and pave the way to study the neuronal population in health and disease.";148635,6;148635,6;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;FUNDACAO D. ANNA SOMMER CHAMPALIMAUD E DR. CARLOS MONTEZ CHAMPALIMAUD;PT;;;;1;0;0;1;0;0 209792;749084;Motivageing;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Motivation–cognition interaction in healthy ageing and Parkinson’s disease;2018-02-01;2021-01-31;;Europe is greying. This has enormous economic and social costs for the entire society, through greater numbers of healthy older adults with cognitive decline, and of people with neurodegenerative disorders that can lead to dementia, such as Parkinson’s disease (PD). MOTIVAGEING aims to address this issue by proposing a new approach for the enhancement of working memory (WM) capacity, in order to improve cognitive function, quality of life and wellbeing of healthy older adults and PD patients. In fact, there is no current effective treatment for age-related WM decline or WM deficits and related behavioural and affective problems in PD patients. Based on a promising new theory of cognitive neuroscience, the Motivation-Cognition Interaction (MoCoInt) framework, the present plan employs an interdisciplinary approach: in Study 1, an innovative multimodal functional neuroimaging method is proposed to analyse for the first time the neural mechanisms of MoCoInt in healthy ageing. The new evidence will provide a foundation for Study 2, in which the efficacy of a novel WM training procedure, based on MoCoInt, will be tested in healthy older adults in order to improve their WM capacity. Finally, to understand if this new training procedure can be employed to treat WM deficits in PD, Study 3 investigates for the first time MoCoInt mechanisms in PD patients in relation to pharmacological treatment, through the conduct of a randomised controlled drug trial. Results will enable to extend MoCoInt to healthy and pathological ageing, and to develop a new framework that will be available as a new theoretical model for both researchers and clinicians. MOTIVAGEING will therefore have both a significant scientific multidisciplinary impact, filling several gaps in knowledge in cognitive neuroscience, cognitive and clinical neuropsychology, and a valuable social and economic impact in the European Union, helping to address the crucial issues posed by the ageing population.;251857,8;251857,8;H2020-MSCA-IF-2016;/MSCA-IF-GF;UNIVERSITY OF KEELE;UK;;;;1;0;0;1;0;0 208735;753595;DrugSearchTool;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Innovative FRET-based toolkit for screening of drugs to fight miRNA-related diseases and its use in the development of cancer treatment with miRNA-96 as a therapeutic target;2018-09-01;2020-08-31;;"The overall goal of this project is to develop a universal FRET-based toolkit for screening of drugs targeting microRNA (miRNA). Specific outcome will be a high-throughput assay for finding drugs targeting miRNA-96, a tumor-suppressing miRNA in pancreatic cancer cells. FRET is the technique of choice and recently, Prof. Marcus Wilhelmsson, Chalmers University of Technology (CHALMERS; project main supervisor) pioneered the development and photophysical characterization of fluorescent base analogues (FBAs) optimized for high-resolution FRET analysis of nucleic acid systems. There is an urgent need in pharmaceutical industry for an in vitro, cell-free, pre-miRNA-small molecule interaction high-throughput assay and also to increase the understanding of the nature of miRNAs. In this project, the unique FRET FBAs will be utilized to develop such assays and to provide new knowledge regarding miRNA structure, dynamics and interactions with other biological molecules or drugs. Apart from taking on the new research field stated above and developing my professional skills, I will bring in new competences to CHALMERS in RNA biochemistry (from the University of Warsaw and Max Planck Institute in Göttingen). Moreover, as part of my training, I will carry out research at AstraZeneca (AZ) and Gothenburg University (UGOT) through secondments. CHALMERS/AZ/UGOT have an established collaboration and I will take full advantage of their R&T capacities in order to gain interdisciplinary and intersectoral expertise as well as to master my skills in scientific communication, scientific writing, coordinating research projects, results exploitation, critical assessment, mentoring, supervision, presentation and networking with other researchers across the globe. This MSCA Postdoctoral Fellowship will help me reaching a position of professional maturity invaluable for starting up my own research group or taking leading roles in industrial R&D organizations.";185857,2;185857,2;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;CHALMERS TEKNISKA HOEGSKOLA AB;SE;;;;1;0;0;1;0;0 210345;754354;EPFLinnovators;SIGNED;H2020-EU.1.3.4.;MSCA-COFUND-2016;H2020;The launch of a new industrial PhD programme at EPFL;2017-10-01;2022-09-30;;"The “E?cole Polytechnique Fe?de?rale de Lausanne” (EPFL) is one of the two Federal Institutes of Technology in Switzerland. EPFL has three missions: i) education, ii) research, and iii) technology transfer. The EPFL is successful in fulfilling these missions, and is ranked as one of Europe’s top institutions with respect to education, research, training-through-research and innovation. EPFL’s doctoral education and training is organized by its doctoral school, which has 19 doctoral programs that cover all EPFL research fields. The doctoral school is truly interdisciplinary, and goes across all EPFL’s disciplines. The more than 2000 doctoral students are all inscribed in one of the 19 doctoral programmes. This proposal aims to (i) increase the awareness among PhD students - at the beginning of their PhD studies - of the possibilities to initiate a start-up, (ii) increase the number of PhD candidates that create a start-up and become entrepreneur/innovator, and (iii) to increase the success of the start-ups that have been created. To this end the “EPFLinnovators” programme will provide excellent PhD candidates with the appropriate training, experience, and guiding, to successfully start and develop their own company. A rich and complete training programme is offered in combination with a long stay, of minimum 6 months and up to 24 months, in the non-academic sector. The programme will result in a new type of “Industrial PhD”. After finalizing their studies, these new PhDs have to possibility to profit from EPFL’s rich infrastructure to support entrepreneurs. The EPFL innovation Park, created to nurture start-ups, is located on the EPFL campus. Through a personal coach, the new PhDs have access to investors (venture capital companies), service providers (e.g. legal), human resources, and funding possibilities. This infrastructure facilitates the transfer of technology from EPFL's research laboratories to the marketplace in Switzerland and Europe.";7534080;3767040;H2020-MSCA-COFUND-2016;/MSCA-COFUND-DP;ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE;CH;;;;1;0;0;1;0;0 209589;748839;NeoLaS;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Novel High-Power Single-Frequency Neodymium-Doped Fibre Lasers;2017-04-17;2019-04-16;;Single-frequency lasers are crucial tools for a variety of applications such as atom cooling, metrology and sensing, among others. However, to date there are still uncovered wavelength domains due to technological challenges, especially in the 900-940 nm and 455-470 nm windows for applications demanding robust systems. This project mainly focuses on the investigation of novel high-power single-frequency lasers at these wavelengths, in both continuous wave and pulsed operation. The outstanding features of fibre laser technology make it the best option to surpass the power limitations of other technologies. To date multi-Watt neodymium-doped fibre lasers have only been demonstrated in a longitudinal multimode operation using resonant cavity configurations. The development of multi-Watt-level single-frequency lasers at 910-940 nm remains a challenge not yet achieved. However, in this project we propose a radical new approach which is based on novel exotic fibres doped with neodymium in a master-oscillator power amplifier configuration. Using this new approach, the applicant has already demonstrated a single-frequency fibre laser at 922 nm with 1 W output power during a post-doc position at the host centre. This preliminary results lays a solid foundation for the success of the project. The main goal of the project is to continue pushing beyond the state of the art, developing new, robust high-power lasers in the 910-940 nm wavelength range, and in the 455-470 nm window by second harmonic generation. The project aims to develop new laser systems for both advanced atomic physics and dermatological applications. This interdisciplinary project will combine the fellow’s expertise in single-frequency fibre lasers with the world-leading expertise of the host group in high-power low-noise lasers. In addition, the project will benefit from the host’s well-established partnerships with academia and industry actors at the forefront of photonics in France.;173076;173076;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FR;;;;1;0;0;1;0;0 208623;747857;MIGWEB;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;A Comparative Diachronic Analysis of Post-Byzantine Networks in the Early-modern Europe(15th-18th c.);2017-07-01;2019-06-30;;"The research proposed here will focus on the connections of post-Byzantine émigrés to the early-modern European West. The Researcher will examine how these webs were organized, controlled and enacted to keep together émigrés of various backgrounds, generations and interests for longer periods of time and in changing historical circumstances; then, it will survey how the nods established by these bonds facilitated interactions between the émigrés and their host societies; lastly, it will analyse the diffusion and “behaviour” of these networks, seeking significant mechanisms and potential common patterns that channeled the key integration processes in a wider context of early-modern Europe. The core part of the research will be done in the Host Institution's premises; apart from its resources, the Researcher will use extensive library collections and archival materials located in institutions related to the Host Institution, or the ones that generally sustain scholarly research in the humanities. The research will be followed by intense training and networking that will allow efficient transfer of knowledge. From the Host Institution, this transfer will aim at enhancing the Researcher's capacities in working with latest theoretical and technological tools, which will, consequently enhance the visibility of her work in the international field academia, as well as a further transfer of this knowledge and specific research outcomes to the related projects and regions of EU with which the Researcher is or will be collaborating. The Researcher, from her end, will transfer her field expertise in working with CE and SEE field contexts, as well as her skills in publishing, program development and coordination, and field networking. Among outcomes of this collaboration will be scholarly publications and conference presentations that target international interdisciplinary audience, as well as a new digital tool that will allow further studies of the field.";195454,8;195454,8;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;ROYAL HOLLOWAY AND BEDFORD NEW COLLEGE;UK;;;;1;0;0;1;0;0 209417;753937;eSEAS;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Enhancing Seafood Ethics and Sustainability: A Values and Ecosystem-based Management Approach;2017-06-01;2019-07-31;;"This project aims to explore new ways of securing seafood sustainability by embedding ethics and values in the management framework. In resource management and governance the explicit articulation of values is missing. Values can aid decision-makers in resolving inherent policy trade-offs that emerge at the science-policy nexus. This will facilitate more transparent, accountable, and inclusive public decision-making. eSEAS’ objectives are threefold: a. to promote cutting-edge, interdisciplinary research in the nascent field of seafood ethics; b. to develop three innovative multidisciplinary “fit-for-purpose” decision-support tools to enhance seafood ethics and sustainability; and c. to implement ethical approaches to European management challenges, including the complex multijurisdictional Norwegian-spring spawning and North Sea herring fisheries. The eSEAS action consists of five integrated research and training activities: 1. to define seafood ethics in relation to marine resource sustainability, policy, and governance within a post-normal science approach; 2. to develop an integrated ethical triage approach to assess sustainability with ethical indicators and test it for the balanced harvesting approach; 3. to conduct value chain analyses of European case studies, in response to consumer demand for ethical seafood; 4. to refine the values- and ecosystem-based management approach (VEBMA) I developed by incorporating a robust knowledge quality assessment and a game-theoretical / agent-based modelling approach to search for stable equilibria given stakeholder preferences; and 5. to introduce an ethical approach and apply aspects of the refined VEBMA to the NSS and North Sea herring fisheries management at ICES participatory workshops. Through public engagement and dissemination, eSEAS will catalyze a science-society dialogue and collective actions to enhance seafood ethics and sustainability.";208400,4;208400,4;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;UNIVERSITETET I BERGEN;NO;;;;1;0;0;1;0;0 208612;747458;MYSOBIO;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;MYcenaean SOcial BIOarchaeology: Deciphering the interplay of funerary treatment and social dynamics in the Mycenaean period;2018-01-15;2020-01-14;;MYSOBIO investigates the complex relationship between funerary treatment and wider social dynamics through a novel interpretive model based on the contextual analysis of human skeletal remains and associated mortuary data. The research focusses on the post-mortem treatment of the body in collective mortuary assemblages. The main aim is to reconstruct, to a new level of detail, development in Mycenaean mortuary practice in the Late Bronze Age Aegean (1700-1050 BC). MYSOBIO will unravel the diversity of social responses at death and their mutual relationship with wider socio-political developments, instrumental in the rise and fall of the Mycenaean palaces, one of the first complex societies in Europe. To achieve this, it employs, for the first time, a holistic bioarchaeological approach that integrates up-to-date theoretical reflection in mortuary archaeology with cutting-edge, interdisciplinary scientific advances in the study of collective skeletal assemblages. This methodology brings together traditional archaeology, current mortuary theory, biological anthropology, funerary taphonomy, forensic sciences and archaeo-thanatology, further enhanced by state-of-the-art technological innovations from other scientific fields (social geography, applied mathematics, geomatics and archaeogenetics). The Fellowship will offer to the Experienced Researcher (ER) the opportunity to receive advanced training in these fields and achieve the research objectives, creating a new methodological pathway to the social dimensions of prehistoric mortuary assemblages with world-wide implications for Social Bioarchaeology. At the same time, the ER will attain professional maturity and greatly advance her career perspectives. She will acquire significant transferable skills, establish lasting multidisciplinary research networks, motivate the youth and educate the public on the social significance of archaeological research and the benefits of science.;183454,8;183454,8;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;UK;;;;1;0;0;1;0;0 208963;748896;GRECO;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Groundwater effects on coastal ecosystems;2017-04-01;2019-03-31;;"Coastal lagoons host some of the most dynamic, diverse and productive ecosystems on Earth, which are subject to significant pressure from human activities. Hydrological land-ocean connectivity is a universally accepted important driver of coastal ecosystems, but the ecological effects of groundwater and associated solute fluxes to coastal systems remain poorly understood for most of the world’s shores. The overall goal of GRECO is to evaluate the role that groundwater fluxes play in the functioning and vulnerability of coastal lagoon ecosystems, by studying its effects on primary producers. This project encompasses a suite of innovative and interdisciplinary investigations aimed at (a) documenting the spatio-temporal distribution of groundwater-derived freshwater and nutrient inputs to lagoons and the exposure of benthic communities to groundwater-borne nutrients; and (b) evaluating the groundwater-derived effects on lagoon primary productivity by identifying the nutrient sources for primary production and the role of groundwater in lagoon ecological functioning. To these aims, two economically and ecologically important French lagoons with contrasting hydroecological conditions will be investigated by using new methods for coastal groundwater studies: 3D hydrodynamic numerical modeling and nutrient stable isotope analysis in primary producers. The novel understanding of groundwater-ecological interactions derived from this project will significantly advance the state-of-the art of groundwater studies in the coastal zone by providing direct evidences of ecological effects of groundwater discharge and by adding new methods to study groundwater implications. The results of GRECO will allow closing a current gap in the fundamental understanding of coastal processes, improving our capacity to sustainably manage hydrological and ecological resources in the coastal zone.";173076;173076;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;UNIVERSITE D'AIX MARSEILLE;FR;;;;1;0;0;1;0;0 209632;751267;SAREE;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;The Social Anthropology of Rabies Epidemiology and Elimination;2018-09-15;2021-09-14;;"Rabies is a viral disease transmitted to humans through the bite of rabid animals, predominantly domestic dogs. It is ranked among the highest priority zoonotic neglected diseases by major international human and animal health organizations (the World Health Organization and World Organisation for Animal Health) and its control is considered a global public good. Although rabies is preventable through administration of post-exposure prohylaxis to individuals exposed to suspect rabid bites and mass vaccination of dogs, the disease still kills thousands globally. India has the highest number of rabies deaths in the world for reasons that are likely to be as much socio-cultural as they are biological, although these factors have neither been investigated nor integrated with epidemiological data. In India, I will focus on two contrasting (based on linguistic, cultural and religious background) rural areas of Gujarat and Maharashtra, where rabies is very prevalent. I will first investigate cultural and religious aspects shaping attitudes towards dogs and local-level acceptance of rabies control and prevention measures, including dog vaccination and human rabies prevention. I will subsequently explore the feasibility and acceptability of in-depth epidemiological data collection tools, contact tracing, to understand cultural and religious influences on people’s health seeking behaviour, practices that may lead to increased rabies risks, and management of these risks within this particular socio-cultural context. Data gathered in this preparatory phase will ultimately inform the design of culturally acceptable and integrated One Health interventions that will to contribute to reduced rabies exposures and mortality. Together with these expected health benefits, my project will demonstrate the added value of One Health, interdisciplinary, approaches to the study and management of zoonoses, and will therefore address an evidence gap of global health relevance.";269857,8;269857,8;H2020-MSCA-IF-2016;/MSCA-IF-GF;UNIVERSITY OF GLASGOW;UK;;;;1;0;0;1;0;0 209516;741941;SELFCEPTION;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Robotic self/other distinction for interaction under uncertainty;2017-05-01;2019-04-30;;"There will be around 35 million private or non-industrial use robots in the world by 2018, a market of 19 billion euros. However, autonomous robot technology in Europe is not yet ready to lead this high expectancy due to the lack of robust functionality in uncertain environments. Particularly, safe interaction is an essential requirement. A basic skill, still unachieved, is to allow the robot to be aware of its own body and perceive other agents. Recent evidence suggests that self/other distinction will be a major breakthrough for improving interaction and might be the connection between low-level sensorimotor abilities and conceptual interpretation. Advanced sensorimotor learning combined with new multimodal sensing devices, such as artificial skin, makes now possible that the robot acquires its perceptual representation, and I hypothesize that learning the multisensory-motor spatiotemporal contingencies permits self/other distinction. Hence, the aim of the project is to provide a hierarchical probabilistic model for self/other distinction in robots, learning the sensorimotor contingencies during interaction. This model not only provides a holistic solution for building the perceptual schema and improves interaction under uncertainty but it might also give insights about how humans construct their own perceptual representation and the sense of agency. Finally, the model will be tested in a whole body sensing humanoid and validated in a service robot in collaboration with a robotics SME. I will use an interdisciplinary approach that combines probabilistic and information sciences modelling with cognitive psychology, creating a highly attractive career profile. SELFCEPTION will boost the materialization of the next generation of perceptive robots: multisensory machines able to build their perceptual body schema and distinguish their actions from other entities. We already have robots that navigate and now it is the time to develop robots that interact.";159460,8;159460,8;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;TECHNISCHE UNIVERSITAET MUENCHEN;DE;;;;1;0;0;1;0;0 209001;750445;RF-MAFS;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Novel RF Driven MRI Magnet for Imaging Enhancement;2017-09-04;2019-09-03;;The key goals of the RF-MAFS project are: the training of the Experienced Researcher (ER) Dr. Javier Alonso-Valdesueiro, in the fast growing field of Scientific Instrumentation, where the host and partner institutions have critical knowledge and expertise and the design, development and optimisation of a new Magnetic Resonance Imaging (MRI) machine based on the concept of Radio-Frequency Magic Angle Field Spinning (RF-MAFS). The aim of the research project is to design and develop a novel type of portable MRI scanner which enhances the image resolution by applying a rotating magnetic field. This project brings together Engineering Skills, Magnetic Resonance (MR) Knowledge and Medical Imaging Insights. Therefore, it will clearly have a broad positive impact on the European Research Area (ERA). The interdisciplinary and intersectoral training program includes specific training in RF power devices, magnet design and training in transfer of knowledge from academia to industry. Then, it will enhance and broaden Dr. J. Alonso-Valdesueiro´s expertise in Applied Scientifc Instrumentation, increasing his exposure to both academia and industry. The Fellow is a talented researcher who has gained much expertise in engineering applied to NMR during his postgraduate career. This background is of great value for the optimization magnet design for medical imaging. But for further boost his career, Javier needs to gain expertise in prototype construction for scientific applications in which the University of Basque Country has a world-recognised expertise. Additionally, through the three-month secondment at University College London he will have contact with the medical image processing part of the action. Therefore, The multidisciplinary project activities including outreach activities, supervision, and complimentary course outlined in the work plan, reflect all training objectives and will assist Javier in acquiring necessary competences and reaching professional maturity.;170121,6;170121,6;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA;ES;;;;1;0;0;1;0;0 209370;752179;HousePoetics;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;House Poetics. An 'assemblage' approach to the production and transmission of value in Bronze Age Crete.;2017-10-01;2019-09-30;;The Project explores the fundamental social question of the creation of value, by investigating House Societies in Bronze Age Crete (3100-1200 BC). Houses are understood as intergenerational, locus-bound social groups, holding an estate of material and symbolic wealth, transmitted along a real or imaginary line, legitimized by kinship or affinity, or both. Because of their distinct focus on the creation and transmission of value, Houses are an ideal framework for answering this research question, but their longevity makes it difficult to explain change. By fusing Houses with the philosophical and sociological premises of Assemblage theory, which argues that social entities are not fixed but constituted by relationships between humans, non-humans and materials that can territorialize and deterritorialize value, the project creates a new social ontology which perceives Houses in a constant state of becoming, continuously affecting and being affected by the changing social world they inhabit. The methodological advantage of this interdisciplinary model, combining philosophical, sociological, archaeological and scientific perspectives, will be demonstrated empirically through the integrated use of GIS spatial analysis and material culture analysis, in a series of case studies (selected on the basis of availability of good contextual information for primary data and a large corpus of published evidence) targeting three strategic scales of House formation and interaction: a single site (Petras), its regional context (East Crete) and their broader geopolitical networks (the Aegean and the East Mediterranean). Using GIS to explore Houses as Assemblages will offer an original integration of spatial, material and social scales, which can revitalize our understanding of past societies and transform the study of social relations in general.;172800;172800;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;UNIVERSITE CATHOLIQUE DE LOUVAIN;BE;;;;1;0;0;1;0;0 209290;748698;HECoW;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Household Ecology. Consumption and Wellbeing in Early Modern Iceland;2017-05-01;2019-04-30;;"'HECoW's aims are to quantify and qualify an observed increase in domestic consumption in early modern Iceland (1750-1900) in order to assess the effects new household material culture had on gender relations and the wellbeing of families. This will be achieved through an truly interdisciplinary, historical and archaeological, methodology applied to two different data sources: historical probate inventories and artefact assemblages from archaeological excavations. These sources will provide information on what new materials were consumed by families during this period, how their introduction and spread varied across the social spectrum, from poorer labourers to land owning farmers, and how they were distributed through time. The project will be supervised by Prof. Lucas, who is a leading thinker in archaeological theory and practice. His supervision will provide the applicant with new abilities in archaeological analysis and increase her confidence in interpretation and communication of archaeological data. Specifically, his expertise in materially focused approaches and relational archaeology will guide the candidate in the application of the project's central theoretical concept of 'household ecology' through which the affects of new material culture on gender relations and the wellbeing of households will be assessed. The project's co-supervisor is Prof. Jónsson, who will train the applicant in historical approaches and the quantitative and qualitative analysis of probate inventories. Prof. Jónsson is an expert in Icelandic medieval and late medieval history and has studied Icelandic probate inventories and their use in historical research. His guidance will supply the applicant with new transferable skills in historical research, which will increase her employability and competence as a researcher. The University of Iceland will provide a stimulative research environment and the necessary facilities to carry out this research successfully.'";191325,6;191325,6;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;HASKOLI ISLANDS;IS;;;;1;0;0;1;0;0 208875;745906;FreezeAlz;TERMINATED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Theoretical prediction of spectral biomarkers for Alzheimer's disease enabled by highly efficient and adaptable mutli-level response methods;2017-07-01;2019-06-30;;"Luminescent conjugated oligothiophenes are highly promising candidates for biomarkers for amyloid misfolds and thereby for early-stage detection of neurodegenerative diseases such as Alzheimer’s and Parkinson's disease. The elucidation of the microscopic mechanism and design principles behind these biomarkers requires theoretical assistance. Finding suitable theoretical models that allow sufficiently accurate spectra calculations for such large, dynamic, and complex biomolecular systems is a highly challenging task: In practice, it is currently neither possible to include all possible factors, nor to rigorously test their importance for the actual simulation. There is, hence, a great need for efficient and adaptive theoretical models capable of incorporating the essential factors in spectra calculation of biomolecular systems sufficiently accurately. In order to devise an efficient and adaptable methodology for assisting the interpretation of existing spectra and predicting the performance of new candidates for biomarkers, we will combine the advantages of several state-of-the-art computational methods. More precisely, we will combine the so-called frozen density embedding scheme with linear scaling density functional theory techniques and incorporate additional polarization effects in a manner inspired by the polarizable embedding method. We will moreover devise efficient and pragmatically adaptable schemes to accurately capture vibrational coupling in these spectra. All these method developments will be done in close collaboration with groups conducting the actual experiments. In this way, a strong interdisciplinary research project will be established. Still, the formulation and implementation of the new methods will be as general as possible in order to devise flexible methods that can easily be adapted to assist the investigation of also other future scientific questions.";173857,2;173857,2;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;KUNGLIGA TEKNISKA HOEGSKOLAN;SE;;;;1;0;0;1;0;0 208961;748889;NANOCANCER;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Getting new insights into the radio-sensitization effects of nanoparticles in photon and charged particle therapy;2017-10-30;2019-10-29;;The use of high-atomic-number nanoparticles (NP) as tumour radio-sensitizers has been recently proposed as a breakthrough in radiotherapy (RT). Numerous biological studies have shown the enhanced effectiveness in tumor cell killing when NP were associated to photon RT and, more recently, to charged particle therapy. However, the mechanisms of action are not clear yet. In addition to the damage due to a possible local dose enhancement (physical effects), the interaction of NP with essential biological macromolecules could lead to changes in the cells (biochemical effects) leading to an amplified effect of the radiation. Within this framework, the main goal of the NANOCANCER project is to get deeper insights into the mechanisms underlying the amplification of radiation effects of NP. For this purpose, I will use a multidisciplinary strategy to evaluate both the biochemical and physical effects involved in these innovative nano-RT approaches. Vibrational spectroscopy (Fourier transform infrared, FTIR, microspectroscopy) will be employed for the first time to investigate the biochemical features in glioma cells combining two high-Z standard nanoparticles (Au and Gd) and charged particle beams. Physical effects will be also assessed by performing complementary Monte Carlo simulation of radiation transport, which will allow a realistic modelling of early biological damages induced by the radiation at the nanometre scale. This interdisciplinary proposal will be essential to better characterize the radio-sensitization effects of NP in glioma cells and, in addition, will bring light to the present charged particle therapy radiobiology, which seems to lead to substantially different tumour responses with respect to conventional RT at the cellular and molecular level. The knowledge of these biochemical features will help researchers to develop RT by taking full advantage of the underlying biology an enhance the therapeutic index of RT for diseases with poor prognosis.;158121,6;158121,6;H2020-MSCA-IF-2016;/MSCA-IF-EF-SE;CONSORCIO PARA LA CONSTRUCCION EQUIPAMIENTO Y EXPLOTACION DEL LABORATORIO DE LUZ SINCROTRON;ES;;;;1;0;0;1;0;0 208897;746525;coolDips;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Direct cooling of dipolar molecules;2017-05-01;2019-04-30;;Full quantum control of molecules has been an outstanding goal for decades. Cooling molecules provides a most promising answer to address this challenge. With recent progress in experimental quantum physics, such cooling is finally within reach. The aim of this project is to demonstrate the novel technique of molecular laser cooling for a gas of barium monofluoride molecules. Realizing a cold gas of these dipolar molecules will pave the way for a large number of novel and interdisciplinary applications ranging from few- and many-body physics to cold chemistry and tests of fundamental symmetries. The combination of this unique research project with the excellent environment for training, networking and research at the University of Stuttgart will ideally prepare the applicant, Dr. Tim Langen, for a future career as an independent research group leader.;159460,8;159460,8;H2020-MSCA-IF-2016;/MSCA-IF-EF-RI;UNIVERSITAET STUTTGART;DE;;;;1;0;0;1;0;0 209538;746094;nanoPhotoMat;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Development of nano-Photocatalytic Materials for Indoor Air Purification and Odour Elimination;2017-06-05;2019-06-04;;Pollutants released directly to the air are particularly harmful compared to soil and water pollutants. These pollutants severely affect people’s life quality and life expectancy. Indoor air purification at highly populated urban areas is technically challenging, because indoor air contaminants arise from both outside and indoor sources. The most hazardous indoor pollutants are volatile organic components, toxic inorganics, dust, bacteria, pollen and mold spores. Conventional ventilation brings outdoor air pollution inside the buildings and thus increases energy consumed for cleaning per room. Adapting new technological advances will help meeting requirements of a compact, reliable, and eco-friendly design. The main objective of this proposal is therefore to develop the next generation air purifiers where photocatalytic oxidation (PCO) technologies will allow elimination of a variety of hazardous indoor air pollutants, and bad odour caused by such pollutants, when illuminated by low-power light sources on-the-fly. The proposed project composes of four different phases: the state-of-the-art design of photocatalysts, selection of proper illuminating source, configuration of PCO system, and preparation of the first prototype. In this study, we will address the limited work performed within the field hitherto, such as the mechanism of catalyst deactivation, efficiencies of odour removal, generation of by-products, electron-hole recombination phenomenon, and the ways of providing anti-bacterial/good hygiene properties. We will carry out an in-depth investigation on optimization of PCO air purification system within an interdisciplinary work at Arçelik Central R&D. After designing a viable configuration, we will focus on the production of a PCO air purifier prototype. In accordance with Arçelik Group’s policy and vision, our final goal is to ready the highly energy-efficient, low-noise, and reliable PCO air purifier prototype for the product launch in the global market.;145845,6;145845,6;H2020-MSCA-IF-2016;/MSCA-IF-EF-SE;ARCELIK A.S.;TR;;;;1;0;0;1;0;0 209524;743642;FCSpecTRe;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Frequency Comb Spectroscopy of Temperature-dependent Reactions;2017-07-01;2019-06-30;;This goal of this project is to obtain a deeper, molecular level understanding of chemical reactions important to atmospheric and planetary chemistry, specifically reactions involved in the oxidation of organic sulfur molecules. A common theme to experimentally determining chemical reaction rates is to monitor the disappearance of a reactant, perhaps even under pseudo-first order conditions. An ideal experiment, however, would monitor the loss of each reactant and the appearance of each product, under known temperature and pressure conditions, in order to gain a more complete picture of the reaction. This project is a significant step towards the ideal kinetic experiment. Here, mid-infrared cavity-enhanced direct frequency comb spectroscopy (CE-DFCS), a technology used almost exclusively in the physics community, will be used as a tool in the chemistry community to spectroscopically identify reactants, transient species, and products based on their vibrational absorption spectra. This is a rapid, sensitive, broadband, and high-resolution technique, which enables reaction rates to be derived based on the simultaneous measurement of both the reactant disappearance and product appearance. Moreover, CE-DFCS will be coupled to a pulsed Laval supersonic expansion, an essentially wall-less reactor with well-characterized pressure and temperature conditions. Temperature dependent rate constants will be measured over a wide temperature range, relevant to Earth’s atmosphere or even parts of the interstellar medium. This project has a strong interdisciplinary component, combining optical physics, fundamental physical chemistry, and atmospheric chemistry. This attribute arises from the significant two-way transfer of knowledge between the researcher and the Atmospheric and Planetary Chemistry group at the University of Leeds. In addition, the fellow will receive training during the tenure of the fellowship to enable her to become a successful independent scientist.;183454,8;183454,8;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;UNIVERSITY OF LEEDS;UK;;;;1;0;0;1;0;0 208762;762938;SEMCRI 2017;SIGNED;H2020-EU.3.6.;IBA-SC6-EUROMED-2016;H2020;Maltese Presidency Conference on Strengthening Euro-Mediterranean cooperation through Research and Innovation;2016-11-15;2017-11-14;;"During the Maltese Presidency of the Council of the EU, the Malta Council for Science and Technology (Ministry for Education and Employment) proposes to hold a conference with the participation of the Research Ministers of the EU Member States and non-EU Mediterranean countries on “Strengthening Euro-Mediterranean cooperation through Research & Innovation”. The conference will comprise a high-level technical meeting on 3rd May 2017 that will feed a Ministerial Conference on 4th May 2017. The conference is expected to result in the 'Valletta Declaration on Strengthening Euro-Mediterranean Cooperation in Research and Innovation', which will take stock of progress made in Euro-Mediterranean R&I cooperation, while looking ahead towards the implementation of the major large-scale initiatives that are being rolled out in the region as well as sowing the seeds for potential future priorities during the final part of Horizon 2020 and beyond. These areas reflect the overall objectives of the proposed conference: 1. Partnership for Research and Innovation in the Mediterranean Area - PRIMA. 2. Addressing the root causes of migration: the role of research. 3. R&I for blue jobs and growth in the Mediterranean Area. The conference resonates well with the three overarching priorities of the Maltese Presidency of the Council of the EU, namely: Mediterranean, Migration and Maritime, and provides a logical thematic focus in research and innovation policy in these key selected areas. The proposed event is expected to have significant knock-on effects on the coordination of efforts in R&I cooperation and support to R&I capacities by different services of the Commission as well as at bilateral or multilateral levels of on-going cooperation in the Mediterranean. The proposed event draws on existing knowledge and expertise provided by EU-level setups and networks in the Mediterranean area as well as interdisciplinary participation covering the range of fields addressed by the event.";144500;144500;H2020-IBA-SC6-EUROMED-2016;/CSA;MINISTRY FOR EDUCATION AND EMPLOYMENT;MT;;;;1;0;0;1;0;0 208942;748364;EsterPep;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Polyester/Polypeptide hybrid biomaterials for biomedical scaffolds;2017-04-01;2019-03-31;;Next generation bioabsorbable and biocompatible polymeric biomaterials are key for the development of new medical devices and advanced approaches in healthcare with significant impact on applicable and affordable treatments for EU citizens. EsterPep will bring together the expertise of the applicant in organo-catalytic synthesis of polyesters with the expertise of the host in synthetic polypeptides and medical applications with the objective to design a new class of poly(ester-peptide) hybrid materials fully based on natural raw materials. The marriage of both systems promises novel functional, processible biomaterials with adaptable material and degradation properties not available from the individual building blocks alone. The objective will be achieved in an interdisciplinary approach combining polymer chemistry and biomaterial science as well as the demonstration of processing feasibility into a biomedical scaffold for tissue engineering. The workpackages have been designed to balance synthetic and application work as well as offering opportinities for intersectorial contacts to benefit the applicants experience. This project is ideally suited to the MSCA-IF programme as it provides mobility and a nurturing, world-class environment for the applicant to embark on a future professional academic career. This will be achieved by developing relevant competences and skills supporting this career path combined with unique scientific training in applied biomedical and biomaterial science guided by a tailored Career Development Plan. The dissemination of research results will target professional audiences as well as communicating to the general public through outreach activities.;175866;175866;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;ROYAL COLLEGE OF SURGEONS IN IRELAND;IE;;;;1;0;0;1;0;0 208730;753002;SMSC;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Single-Molecule Studies on Condensin;2017-03-01;2019-02-28;;For division of each of our cells, 2 meters of DNA should be replicated, compacted into a few-micrometer size chromosomes that are segregated and distributed via mitosis, so that each daughter cell gets exactly one copy. How this large DNA genome is well organized into such a small volume is one of the hottest issues for the understanding of chromosomes. Condensin, a ring-like structure formed by SMC dimers, kleisin, and two heat domains, embraces DNA and condenses the DNA using ATP hydrolysis. However, the molecular mechanism on how conformational changes of condensin compact DNA is still unknown. Here, the applicant Dr. Je-Kyung Ryu proposes to use two orthogonal single-molecule approaches, “high-speed AFM (HS AFM)” and “single-molecule fluorescent magnetic tweezers” to reveal the molecular mechanism of condensin. HS AFM imaging is a unique technique to record video-rate real-time images for entire structure of a protein in physiological condition with high spatiotemporal resolution (~1nm, ~50ms). In addition, using single-molecule fluorescence microscopy combined with magnetic tweezers, the applicant can understand how the cooperative binding of condensin to DNA correlate with DNA condensation. These two approaches will not only provide most important clues to understand the mechanism of condensin how DNA enters and exits the condensin ring and how condensin shapes chromosome but also include technical advances in single-molecule techniques. This work will be carried out in the laboratory of Prof. Cees Dekker, who is a world leader in HS AFM and single-molecule biophysics of DNA-protein interactions. The applicant’s experts in single-molecule biophysics, fluorescence microscopy, and biochemistry will make synergetic effects with the resources of the Dekker lab to collectively meet the interdisciplinary demands of the innovative effort.;177598,8;177598,8;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;TECHNISCHE UNIVERSITEIT DELFT;NL;;;;1;0;0;1;0;0 208883;746058;Basquesmith;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Ironworking technology and social complexity of rural comunities during the Early Medieval Ages;2017-09-01;2019-08-31;;The application of scientific techniques to analyse archaeological materials has greatly influenced modern archaeology, providing archaeologists with the tools to generate datasets, such as those associated with chronological dating and chemical compositions, from which more rigorous interpretations can be developed. The Basquesmith project aims to investigate ironworking production during Early Medieval (EM) times by applying microscopic techniques on an assemblage of materials excavated in rural settlements in the Basque Country (northern Spain), a region renowned for the superior quality of its iron products. Characterisation of the manufacture and repair methods used, the quality of the utensils produced, and the debris generated, will provide valuable insight into which production occurred at the sites. The originality lies in the artefacts themselves as well as the archaeometallurgical approach to investigate these assemblages. Common utensils such as ladles or keys made from iron, which are exceptionally rare in EM rural contexts, allow ironworking to be explored on rural implements from rural communities rather than prestige items from urban contexts. This will result in a truly utilitarian project combining history, archaeology and materials science to investigate a much neglected area for EM Spain. Basquesmith is highly committed to EU's strategy endorsed in the field of Cultural Heritage and is in an excellent position to carry out this research through the promotion of such an interdisciplinary approach. Moreover, Basquesmith integrates the applicant’s knowledge in material science with a top level research group (GIPyPAC) at the University of Basque Country. This network will not only encourage dissemination of the research within the academic literature and spotlight the cultural heritage of the Basque region, but it will also provide a framework which can be applied to the evaluation of technology in rural communities at other archaeological sites.;158121,6;158121,6;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA;ES;;;;1;0;0;1;0;0 208235;748909;RHYTHMSYNC;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Rhythm synchronization between music and spoken language;2017-04-01;2019-03-31;;Rhythm perception is important for a wide range of higher cognitive abilities ranging from time perception to predicting the occurrence of future events, from perceiving language to dancing to the beat of the music. Despite considerable amount of research in rhythm in various scientific disciplines, the way the human mind perceives and produces rhythm is not fully understood. While many interdisciplinary studies look at how performance in one cognitive domain compares to performance in another, it has proven difficult to link the mechanisms for rhythm perception across perceptual and cognitive domains directly. This project therefore looks how rhythm in music and spoken language interact by relying on rhythm synchronization: i.e. the phenomenon that our mind tends to automatically synchronize our motor-activity to the rhythm we perceive auditory (e.g. tapping a finger to the beat of music, the gestures that accompany speech, and singing). Because rhythm in spoken language and music is shaped by experience with culture specific music and our native language, in addition to adults, this project also studies young infants from birth through the crucial early stages of vocal and motor development. The studies in this project rely on a combination of acoustic analyses and electrophysiological methods (sEGM) to determine how rhythm in language and music is synchronized, how synchronization unfolds in time and how differences in rhythm in the two domains affect rhythm synchronization. By looking at similarities and differences in the rhythm of spoken language and music, the project attempts to create a blue-print of the shared and domain-specific cognitive mechanisms necessary for rhythm processing. Because we are surrounded by rhythm in our everyday life, the study of rhythm synchronization can thus help us understand how different rhythms interact and how they influence our daily life and our behaviour.;159460,8;159460,8;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;UNIVERSITAET POTSDAM;DE;;;;1;0;0;1;0;0 215549;797494;JOINTIME;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Connecting Bronze Age Europe: High-precision Radiocarbon Dating 1700-1500 BCE;2018-09-01;2020-08-31;;"Through synergies between archaeology and physics, JOINTIME proposes to provide the first reliable radiocarbon-driven grid synchronising critical parts of Europe, from Scandinavia over the Carpathian Basin to the Aegean, between 1700 and 1500 BCE. Building on mathematically advanced software pioneered by AU Astronomy & Physics (AMS unit), this time-geography will be used as a springboard to pursue answers to the main project question: when and where the Bronze Age was first consolidated as a geographical and culturally interweaving process. This will further prompt comparisons with prevalent macro-models and involves testing an alternative frame recently proposed by AU Dept of Archaeology: here the Bronze Age is conceptualised as an interconnecting web-like process, which unfolded decisively c. 1700-1500 BCE when large tracts of Afro-Eurasia became knit by bronze and by many other transactions. Jointime aims to pinpoint the mode, direction and intensity of sociocultural interactions in the decisive period of Bronze Age consolidation. The anticipated results will be ground-breaking in Bronze Age studies as well as beyond. The project is timely since advanced modelling methods are now available and rich data are merely awaiting targeted, systematic and explorative analyses. The training of Tibor-Tamás Daróczi as experienced researcher at AU will ensue along these interdisciplinary lines in tune with the objectives of the planned research. The training will follow a detailed scheme of supervision and courses, with a full integration into the hosting department of archaeology and with a transfer to the AMS unit twice a week: embracing elements from scientific statistics to culture theory. His academic network will complement the ones of the host and guarantee mutually beneficial success. Passion, stamina and curiosity will ensure completion of the fellowship and results of excellence. The obtained skills crossing natural sciences and SSH will ensure high employability.";200194,8;200194,8;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;AARHUS UNIVERSITET;DK;;;;1;0;0;1;0;0 207799;703374;NMR4Nanos;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Development and application of NMR-based tools to inorganic nanocarriers for effective vaccine delivery;2017-09-04;2019-09-03;;"There is an urgent need for new vaccines, but avoiding side effects is crucial for patient compliance. To address this, new generation vaccines with safe, but weakly immunogenic antigens are formulated with carriers and adjuvants to induce the desired immunological response. Inorganic nanoparticles (NP) have shown potential as carriers while immune stimulators of microbial origin are proven to ensure long lasting immune response. Their successful integration into nanovaccines requires thorough analysis of the inorganic/organic interface. Solution state NMR spectroscopy has recently been established as a potent characterisation tool towards this end. My objective is twofold: I intend to elaborate new vaccine-carrier nanosystems and to develop NMR spectroscopic surface characterization methods for their analysis that may be generalized for application to other NPs. I will use my expertise in preparative colloid chemistry to tailor series of new ZrO2- and hydroxyapatite-based NPs of varied size. For their characterisation I will be trained to carry out solution NMR measurements from the toolbox developed by the Host. The outcome will be invaluable for guiding the surface modification of these NPs to obtain vaccine carriers. The project also aims at the further development of NMR methodology. The potential of solid state NMR measurements in this respect will be explored as a secondment. Another secondment is devoted to the early study of in vitro stability, fate and toxicity of the new carriers. The planned research will train me in a cutting-edge analysis technique, and by that means provide me more independence in my work. Furthermore, it will establish an interdisciplinary cooperation between Partner Institutes. The results and the planned outreach activities are also expected to have a positive impact on EU: these new characterization tools would be useful for food, cosmetic and nanomedicine industries and may contribute to improved customer and patient safety.";172800;172800;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;UNIVERSITEIT GENT;BE;;;;1;0;0;1;0;0 208388;749461;DUST-GLASS;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Improving global dust prediction and monitoring through data assimilation of satellite-based dust aerosol optical depth;2017-05-01;2019-04-30;;DUST-GLASS aims at improving global dust prediction and monitoring by optimizing an advanced data assimilation system (LETKF scheme) coupled with a sophisticated atmospheric-dust model (NMMB/BSC-Dust). For the accomplishment of these core scientific goals, a fine resolution (0.1o x 0.1o) global dust optical depth (DOD) database, suitable for data assimilation, will be developed via a synergy of state-of-the-art Level 2 satellite retrievals acquired by MODIS, MISR and OMI sensors (2007-2016). The impacts of assimilating this novel dataset (DOD) on model’s predictive skills, both at global and regional scale, will be assessed objectively. Global forecasts (5 days) will be carried out for different periods aiming at studying dust aerosols’ mobilization and transport from the major dust sources of the planet, while a global reanalysis (0.5o x 0.7o) dataset will be generated for long-term dust monitoring. In addition, regional short-term (84 hours) forecasts will be conducted for 20 Mediterranean dust outbreaks identified by a satellite algorithm in the framework of the MDRAF project (fellow’s previous MC-IEF). In the evaluation analysis, the model’s dust outputs will be compared versus measurements derived by ground networks (AERONET, MAN, ACTRIS) as well as against columnar/vertical satellite retrievals (MODIS, MISR, CALIOP). Moreover, temperature and radiation will be also considered since “corrections” on dust fields, thanks to data assimilation, are expected to be evident on both parameters due to dust-radiation interactions. The aforementioned variables will be compared against observations obtained by ground networks (ISB, RAOB, BSRN) and reanalysis/analysis products (ERA-Interim, FNL). Considering the multifaceted role of dust, the scientific outcomes of DUST-GLASS are expected to contribute effectively to interdisciplinary studies regarding dust aerosols as well as their associated impacts on health, anthropogenic activities, environment, weather and climate.;164653,2;164653,2;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;NATIONAL OBSERVATORY OF ATHENS;EL;;;;1;0;0;1;0;0 208390;750076;INWELCHAV;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Intersectional Analyses of Welfare Chauvinism in Europe;2017-08-01;2019-07-31;;In the European context of ongoing crises (economical, political and humanitarian), populist radical right parties have consolidated their presence in mainstream politics. These parties sharpened the debate concerning the future of the welfare state, arguing for a separation between the “natives” of the ethnic majority, as self-evident targets for full welfare provision, and those belonging to a generic “other”–wherein migrants, ethnic minorities, racialized groups, people with alternative lifestyles are lumped together. However, both studies of the populist radical right and welfare studies are missing an intersectional awareness to how such conceptual distinction is operated. Taking a decidedly interdisciplinary approach, the present project aims to explore and scrutinize in a comparative framework the populist radical right’s discursive (re)construction of cultural identities and the terms of national belonging at times of economic, political and societal crises across Europe, from an intersectional perspective. The project will combine political sociology, with a focus on welfare and populism studies, intersectionality, and critical discourse analysis. The project focuses on three cases: the Finns Party (PS/SF) in Finland, the Greater Romania Party (PRM) in Romania, and the Sweden Democrats in Sweden. The objectives are to provide an account of the communalities and differences in articulating national identity and welfare chauvinism in the chosen countries, and to map out how these are expressed within the common European institutional framework, namely in the European Parliament.;172800;172800;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;UNIVERSITE LIBRE DE BRUXELLES;BE;;;;1;0;0;1;0;0 207815;705572;GSTHgNDD;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Role of GST gene variation in susceptibility to mercury (Hg)-induced neurodevelopmental disorders (NDD) in zebrafish;2017-06-20;2019-06-19;;Environmental factors, including the heavy metal mercury, are recognized as having a dominant influence on the aetiology and prevalence of neurodevelopmental behavioural disorders. This proposal will develop a new model for assessing the role of gene:environment interactions, specifically genetic predisposition for toxicity, in risk for disease, and identify early markers predictive of toxicity and later phenotypes. This will directly relate to the EC work program for Health, demographic change and wellbeing, with respect to both 'Personalized medicine' for non-communicable diseases and 'Early development' addressing mental health from childhood to older ages. The project uses the zebrafish model to investigate the relationship between glutathione-S-transferase (GST)-related genetic background, developmental exposure to mercury, and risk for neurodevelopmental disorders. This will be achieved by exposure of wild-type and CRISPR-generated Gst mutant embryos to mercury, and testing whether genetic predisposition leads to increased risk for toxin-induced behavioural phenotypes. We will test for altered biochemical, transcriptomic and epigenomic modifications that may serve as potential early markers for insult. The results obtained in this proposal will have significant impact on the ability to conduct individual and population specific toxicity risk assessment, and may lead to novel measures for early detection of increased risk and alleviation of potential adverse outcomes. The high-quality original research presented in the proposal will not only enable the Experienced Researcher to reach a position of professional maturity in her career, but will also allow her to develop a spectrum of new and interdisciplinary skills, integrating her previous training and knowledge into the behavioural genetics skills set. This project will also allow Dr. Brennan's group to integrate developmental toxicology into existing behavioural research, and will generate new collaborations.;183454,8;183454,8;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;QUEEN MARY UNIVERSITY OF LONDON;UK;;;;1;0;0;1;0;0 207891;724629;DarkMix;SIGNED;H2020-EU.1.1.;ERC-2016-COG;H2020;Illuminating the dark side of surface meteorology: creating a novel framework to explain atmospheric transport and turbulent mixing in the weak-wind boundary layer;2017-05-01;2022-04-30;;"Surface meteorology impacts the abundance and quality of life on Earth through the transfer and mixing of light, heat, water, CO2, and other substances controlling the resources for humans, plants, and animals. However, current theories and models fail when airflows and turbulence are weak during calm nights leaving weather and climate forecasts uncertain. This ‘dark side’ occupies substantial fractions of time and our landscape, its physics are largely unknown, and has eluded proper experimental investigation. DarkMix creates technological and theoretical innovations to observe and explain transport and mixing in the weak-wind boundary layer. Its ambitious goal is a radically new framework incorporating unexplored mechanisms such as submeso-scale motions, flow instationarities, and directional shear to effect a quantum leap in understanding the air-plant-soil exchange. DarkMix will build the ground-breaking first-ever fiber-optic distributed temperature sensing harp to fully resolve the 3-dimensional flow and air temperature fields and enable unprecedented computation of eddy covariance fluxes at scales of seconds over 4 orders of magnitude (deci- to hundreds of meters). Both key innovations bear significant risks of technical and fundamental nature, which are mitigated by pursuing alternatives. Measurements will inform cutting-edge large eddy simulations to test hypotheses. The interdisciplinary dimension takes DarkMix to a unique set of weak-wind sites including a valley-bottom grassland, a forest in complex terrain, and a city to investigate topographic effects, the forest carbon cycle, and the urban heat island. DarkMix will open a new window for surface meteorology and its links to air quality, biogeochemistry, and climate change by giving physically meaningful and societally relevant answers to profound questions such as the exchange of greenhouse gases, hazards from ground fog, urban pollution, and agricultural losses through extreme cold air.";1898103,5;1898103,5;ERC-2016-COG;/ERC-COG;UNIVERSITAET BAYREUTH;DE;;;;1;0;0;1;0;0 208550;741384;CustomCOF;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;New strategies for the formation of two-dimensional covalent organic frameworks (2D-COFs) on surfaces.;2017-10-01;2019-09-30;;"Organic chemistry, including polymer synthesis, has a great impact on society, since many consumer goods would not exist without these chemistries. Most often, organic synthesis is carried out in solution and, despite the fact that it is a proven powerful approach, new synthetic strategies are needed for the formation of the next generation of complex materials. One kind of functional materials that receive great attention nowadays are the so-called two-dimensional covalent organic frameworks (2D-COFs). Basically, these are extremely thin films (one-molecule thick) that are often crystalline in two dimensions, and that contain nanopores. Potential applications of this type of materials range from superthin membranes to advanced electronics. This innovative project deals with the use of surfaces to template the formation of such sophisticated 2D-COFs. New synthetic approaches are explored, not only to generate the next generation of this type of materials with unique topologies and functionality, but also to conceive smaller versions of these 2D-COFs with a well-defined size. In this highly interdisciplinary project, we use atomically flat substrates that act as support for the formation of these new networks. These exciting novel 2D-COFs are not only of interest by themselves, but they also nanostructure and functionalize the surfaces they are adsorbed on. CustomCOF will provide an exceptional platform to acquire new knowledge through research and training, to reach scientific maturity, leadership and independent thinking, strengthening my team-working spirit, individual personal development training and my willingness to assume responsibilities and accept risks, which are always important assets to obtain high-quality results. It will offer networking opportunities and international collaborations. In brief, this MSCA grant will be a turning point in my career towards scientific excellence.";160800;160800;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;KATHOLIEKE UNIVERSITEIT LEUVEN;BE;;;;1;0;0;1;0;0 207870;715980;MultiSense;SIGNED;H2020-EU.1.1.;ERC-2016-STG;H2020;Multisensory signal processing: From brain-wide neuronal circuits to behavior;2017-03-01;2022-02-28;;"Our brain needs to constantly fuse sensory information detected by our multiple senses in order to produce a seamless coherent representation of the world. Rather than being the exception, this binding process is ubiquitous to sensory-motor integration and is implicated in most cognitive functions. Its impairment is a cause of various pathologies, such as schizophrenia or autism. Multisensory processing operates on all brain levels from primary cortices over subcortical structures up to higher associative centers, while the smallest operational units are single multisensory neurons. In an interdisciplinary effort, we combine optical developments, genetics and neuro-computation to obtain new insights into the activity of brain-wide neural circuits that process multisensory information. To reduce the complexity, we study the small transparent brain of zebrafish larvae as a model system. We focus on gaze stabilization as an inherently multisensory model task that is conserved among all vertebrates. This reflex uses both vestibular and visual information to drive eye movements in order to compensate for self-motion and maintain clear vision. We will build a novel experimental platform in which a restrained larva will be submitted to vestibular and visual stimuli, as a pilot in a flight simulator. We will optically record the activity of all 100,000 neurons of the animal brain as it performs multisensory integration tasks. To extract basic principles of how behavior is coded in multisensory neuronal circuits we will interpret the brain-wide activity and the observed behavior with methods from statistical physics. No other system can today provide a similar brain-scale, yet cell-resolved view on the neuronal network dynamics subserving such a complex integration process. Thus, our data will constitute an invaluable arena to test circuit-based models for sensory-motor integration, decision-making and multisensory-motor learning.";1371250;1371250;ERC-2016-STG;/ERC-STG;UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6;FR;;;;1;0;0;1;0;0 207847;714166;NARMESH;SIGNED;H2020-EU.1.1.;ERC-2016-STG;H2020;Narrating the Mesh: Ecology and the Non-Human in Contemporary Fiction and Oral Storytelling;2017-02-01;2022-01-31;;"Today’s ecological crisis prompts us to rethink our attitude towards physical and natural realities that have traditionally been seen as opposed to human subjectivity and agency. What emerges from this “non-human turn” is a sense of our interdependence on things like the bacteria in our intestines or the carbon atoms supporting life on Earth. Ecological theorist Timothy Morton uses the metaphor of the “mesh” to express this idea of human/non-human interconnectedness. This project will map the formal and thematic strategies through which contemporary narrative practices engage with the non-human and envisage this interconnectedness. Storytelling is an indispensable tool for making sense of experience by establishing temporal and causal relations. But it is also biased towards the human-scale realities of action and social interaction. How can narrative overcome this bias? How does it convey phenomena that challenge our belief in the ontological and material self-sufficiency of the human? Comparing fictional narratives in print (novels and short stories) and conversational storytelling, we will systematically explore the ways in which narrative can forge connections across levels of reality, weaving together the human and the non-human into a single plot. The assumption is that narrative is a field where fictional practices are in constant dialogue with the stories told in everyday conversation—and with the culture-wide beliefs and concerns those stories reflect. Through its three sub-projects, the proposed research charts this complex dialogue while greatly advancing our understanding of how stories can be used to heighten people’s awareness of the mesh and its significance. The project builds on a combination of methods (close readings of novels, qualitative analysis of interviews), aiming to open up a new field of study at the intersection of literary scholarship and the social sciences—with narrative theory serving as a catalyst for the interdisciplinary exchange.";1130000;1130000;ERC-2016-STG;/ERC-STG;UNIVERSITEIT GENT;BE;;;;1;0;0;1;0;0 208387;749549;GLYCONHC;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Exploiting carbohydrate/N-heterocyclic carbene hybrid complexes as innovative multifunctional oxidation catalysts with tailoring of weak interactions allowing for development of enzyme mimics;2017-03-01;2019-02-28;;"The key objective of this project is the development of innovative hybrid complexes for oxidative catalysis of pharmaceutically relevant functional groups (e.g. alcohols, amines, olefins), by combining the beneficial properties of triazolylidine N-heterocyclic carbenes and carbohydrates for synergistic catalysis and molecular recognition, ensuring site-specific bind making and breaking processes and tailored delivery. A range of novel carbohydrate-functionalised NHC complexes (e.g. with Ru(II) and Ir(III)) will be synthesised for these purposes and relationships between carbohydrate structure/geometry and catalytic activity probed, complementing experimental approaches with computational insight. NHCs are synthetically versatile and have been demonstrated to have beneficial properties as ligands for catalysis. Triazolylidine NHCs are accessible via modular 'click' chemistry and readiliy functionalised, but not as widely explored as other classes of related compounds. Functionalising carbenes with carbohydrates is practically unknown in the literature despite many advantages such derivatives would possess, including well-defined geometry, rich hydrogen bonding and proton-shuffling interactions, recognition by biological receptors (providing the opportunity for developing NHC-based metalloenzyme mimics through interdisciplinary collaboration) and also chirality (allowing for enantioselectivity). The candidate has synthetic experience matching the project and will benefit from the specific training activities within the host group (who have vast NHC experience), mobility and change of topic to achieve research maturity. Deliverables will include: 1) New catalysts for high-turnover oxidation of pharmaceutically relevant substrates 2) Innovative metalloenzyme mimics based on NHCs embedded in proteins' carbohydrate-receptor sites.";175419,6;175419,6;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;UNIVERSITAET BERN;CH;;;;1;0;0;1;0;0 207790;702130;MUP-Trans-Zagros;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Tracking the Middle to Upper Palaeolithic transition in the Kermanshah Valley, West Central Zagros Mountains, Iran.;2016-10-01;2018-09-30;;The long history of Palaeolithic research in the Kermanshah Valley has revealed a number of sites associated with the Middle to Epipalaeolithic sequences including well-known site of Warwasi Rockshelter. Despite this importance, our knowledge of the Palaeolithic occupation there and even in Iran is suffering from the lack of a clear, up-to-date and scientific work on stratigraphy, settlement systems/dynamics and accurate absolute dating. To overcome some of these problems, the applicant has conducted a Palaeolithic research project in the Kermanshah Valley. This project includes an intensive survey and test excavations around the Warwasi Rockshelter to provide new evidence on the settlement systems, anatomically modern human demography and the process of cultural changes during the Middle and Upper Palaeolithic. This project has resulted into the discovery of 255 Palaeolithic sites and over 7000 Middle though Epipalaeolithic artefacts recovered from the Kermanshah Valley. Furthermore, the test excavations in three caves in the area uncovered stratified Middle to Upper Palaeolithic sequences. The MUP-Trans Zagros aims to identify the ghost lineage between Middle and Upper Paleolithic occupations in one of the key regions in the Middle East by multi-proxy and basic approaches of GIS for settlement systems/dynamics, absolute dates and micromorphology analysis of the newly discovered and excavated sites in the Kermanshah Valley. For these aims, the applicant will be greatly benefited from training and experiences offered by the department of Archaeology & Anthropology at Cambridge University in the interdisciplinary researches on the Eurasian’ Middle to Upper Palaeolithic transition.;195454,8;195454,8;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;UK;;;;1;0;0;1;0;0 207820;706016;MUSDEWAR;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Music in Detention during the (Post) Civil-War Era in Greece (1947-1957);2017-12-01;2019-11-30;;"MUSDEWAR will investigate the use of music in Greek prison camps in the (post) civil-war era (1947-1957). Despite a recent shift in musicology, which has begun to address music’s potential to damage subjectivity, there are still major gaps in the history of music’s use in mass detention camps. Contributing to the wider history of detention camps in the twentieth century, MUSDEWAR will fill this gap by critically examining: (1) the use of music as a means to ‘re-educate’, punish, humiliate and ‘break’ prisoners; (2) ‘performance under orders’: official camp orchestras and choirs; (3) music compositions, performances, and debates on Greek music by intellectuals-detainees. Analysing these aspects will combine historical and empirical research with a critical and theoretical framework. The project will document and reconstruct the use of music and musical life in the camps through archival and textual research, and interviews with former detainees, composers and intellectuals of the time. An interdisciplinary framework will be developed to analyse and interpret research findings, using tools from musicology, history, social anthropology, philosophy, trauma studies and critical theory. MUSDEWAR will deliver a monograph to a major international academic publisher. Moving beyond the humanistic notion of music as an inherently enlightening art, the monograph will synthesize research into an empirically rich and theoretically grounded account of the multifaceted use of music in the Greek camps. Intermediate aims include a project website and two articles to peer-reviewed journals. Actions for networking and knowledge transfer include research presentations, a workshop, a public outreach event (symposium, exhibition), projects in secondary schools, and a proposal for a European Research Council Starting Grant. Results will contribute directly to trans-national public debates about human rights and current forms of detention, particularly with regard to mass asylum seeking in the European Union.";164653,2;164653,2;H2020-MSCA-IF-2015;/MSCA-IF-EF-CAR;PANTEIO PANEPISTIMIO KOINONIKON KAIPOLITIKON EPISTIMON;EL;PANEPISTIMIO THESSALIAS;EL;;1;0;0;1;0;0 207743;702410;HIntNets;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-GF;H2020;Higher-order interactions and Laplacian dynamics in complex networks: structure, dynamics and control;2017-07-01;2020-06-30;;"Complex networks are an essential ingredient of modern life, and underpin integral parts of our biological, physical, technological and socio-economic universe. Thus far, such networks have been mainly represented as graphs. However, while graphs can capture pairwise interactions between nodes, fundamental interactions in networks often take place between multiple nodes. For example, in socio-economic networks, the joint coordinated activity of several agents (e.g. buyer, seller, broker); the formation and interactions of coalitions; the emergence of peer pressure; and the existence of triadic closure are all prevalent. The objective of this interdisciplinary project is to investigate such non-binary interactions in complex networks and their dynamical implications. Specifically, we will investigate how such interactions can be taken into account for the modelling, analysis and design of complex networks. To achieve this, we will extend the geometrical framework of simplicial complexes to account systematically for weighted non-binary couplings of nodes, node-pairs, triplets, etc., allowing us to consistently assess and design higher-order interactions. Here, we will focus on consensus and random walks as prototypical examples of a range of other phenomena. Working at the interface of Network Science and Control Theory, we will combine recent tools from both fields and apply our results to real biological and socio-economic networks and data. We will investigate how the consideration of non-binary couplings can yield an improved understanding of the propagation of external shocks in socio-economic networks, and help to reveal dynamical groupings in networks emerging from systems biology experiments. Providing a synergy between the applicant’s multidisciplinary background and the leading Systems, Optimization and Control research of the hosts, this proposal holds the potential to leverage the candidate’s career and yield scientific results of general relevance.";251857,8;251857,8;H2020-MSCA-IF-2015;/MSCA-IF-GF;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;UK;;;;1;0;0;1;0;0 207621;725594;time-data;SIGNED;H2020-EU.1.1.;ERC-2016-COG;H2020;Time-Data Trade-Offs in Resource-Constrained Information and Inference Systems;2017-09-01;2022-08-31;;"Massive data poses a fundamental challenge to learning algorithms, which is captured by the following computational dogma: The running time of an algorithm increases with the size of its input data. The available computational power, however, is growing slowly relative to data sizes. Hence, large-scale problems of interest require increasingly more time to solve. Our recent research demonstrates that this dogma is false in general, and supports an emerging perspective: Data should be treated as a resource that can be traded off with other resources such as running time. For data acquisition and communications, we have also shown related sampling, energy, and circuit area trade-offs. A detailed understanding of time-data and other analogous trade-offs, however, requires interdisciplinary studies that are currently in their infancy even for basic system models. Existing approaches are too specialized, and crucially, they only aim at establishing a trade-off, but not characterizing its optimality or its technological feasibility. TIME-DATA will confront these challenges by building unified mathematical foundations on how we generate data via sampling, how we set up learning objectives that govern our fundamental goals, and how we optimize these goals to obtain numerical solutions. We will demonstrate our rigorous theory with task-specific, end-to-end trade-offs (e.g., samples, power, computation, and statistical precision) in broad domains, by not only building prototype analog-to-information conversion hardware, but also accelerating scientific and medical imaging, and engineering new tools of discovery in materials science. Our goal of systematically understanding and expanding on this emerging perspective is ambitious: Our mathematical sampling framework, in tandem with new universal primal-dual algorithms and geometric estimators, are expected to change the way we treat data in information systems, promising substantial flexibility in the use of limited resources.";1931574;1931574;ERC-2016-COG;/ERC-COG;ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE;CH;;;;1;0;0;1;0;0 207726;707951;SynchroSelf;TERMINATED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Harnessing reversibility of peptide Self-Assembly processes to Synchronise Extracellular Matrix substitutes with cellular driven tissue reconstruction;2016-04-01;;;"Irreversible tissue loss is a common feature in a large spectrum of health conditions (e.g. aging, trauma, cancer, degenerative diseases, ischemia, etc), placing huge burdens in patient relatives and health care systems. Therapies aiming to restore tissue function will have a great impact in the health and quality of life of millions of people worldwide. Regenerative medicine is an interdisciplinary endeavour to create functional tissues and organs, where cell biology, biochemistry, chemistry and material sciences are central components to address human tissues complexity. The approach comprises the use of biomaterials that temporarily substitute the extracellular matrix (ECM). However, current engineered biomaterials have not fully matched the diverse functionality of native tissues. Thus, fundamental research in biomaterials for regenerative medicine has great potential to provide smart solutions to current bottlenecks in this scientific area. In this project, biomaterials based on peptide self-assembly will be designed to take advantage of reversible supramolecular interactions, in order to create self-healing ECM substitutes. The dynamic nature of these materials will be addressed systematically in an attempt to copycat ECM turnover. So far, efforts from the materials scientific community have been mainly focused on controlling spatial and geometrical features. Perhaps it is time to start addressing consistently time variable controls in biomaterials design, and to pave the way to fully synchronise the biology and man-made materials’ “watches”. We expect that SynchroSelf will generate a new class of dynamic biomaterials that will enable scientists to study wound healing processes in vitro with unprecedented level of complexity and experimental control.";195454,8;195454,8;H2020-MSCA-IF-2015;/MSCA-IF-EF-CAR;QUEEN MARY UNIVERSITY OF LONDON;UK;;;;1;0;0;1;0;0 207276;694995;BIOSEC;SIGNED;H2020-EU.1.1.;ERC-ADG-2015;H2020;Biodiversity and Security: understanding environmental crime, illegal wildlife trade and threat finance.;2016-09-01;2020-08-31;;"The core intellectual aim of BIOSEC is to explore whether concerns about biodiversity protection and global security are becoming integrated, and if so, in what ways. It will do so via building new theoretical approaches for political ecology. Achim Steiner, UN Under-Secretary General and Executive Director of UNEP recently stated ‘the scale and role of wildlife and forest crime in threat finance calls for much wider policy attention’. The argument that wildlife trafficking constitutes a significant source of ‘threat finance’ takes two forms: first as a lucrative business for organised crime networks in Europe and Asia, and second as a source of finance for militias and terrorist networks, most notably Al Shabaab, Lord’s Resistance Army and Janjaweed. BIOSEC is a four year project designed to lead debates on these emerging challenges. It will build pioneering theoretical approaches and generate new empirical data. BIOSEC takes a fully integrated approach: it will produce a better conceptual understanding of the role of illegal wildlife trade in generating threat finance; it will examine the links between source and end user countries for wildlife products; and it will investigate and analyse the emerging responses of NGOs, government agencies and international organisations to these challenges. BIOSEC goes beyond the ‘state-of-the art’ because biodiversity protection and global security currently inhabit distinctive intellectual ‘silos’; however, they need to be analysed via an interdisciplinary research agenda that cuts across human geography, politics and international relations, criminology and conservation biology. This research is timely because in the last two years, the idea that the illegal wildlife trade constitutes a major security threat has become more prevalent in academic and policy circles, yet it is an area that is under researched and poorly understood. These recent shifts demand urgent conceptual and empirical interrogation.";1822729;1822729;ERC-2015-AdG;/ERC-ADG;THE UNIVERSITY OF SHEFFIELD;UK;;;;1;0;0;1;0;0 204939;707482;MWDIR;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Media Warfare and the Discourse of Islamic Revival: The Case of the Islamic State (IS);2017-02-01;2019-01-31;;"This proposal seeks to better our understanding of how Islamist movements use Social Media to reinforce their discourses, ideologies and thoughts during times of conflict, i.e. ideological levels of struggle. In brief, this study takes as its mission the task of unravelling patterns of rhetorical propaganda employed by the Islamic State (IS) and how this movement attracts individuals from all over the world and influences security in Europe and the world. There are two overlapping discourses which dialectically feed into each other: those of religious revival and political emancipation. By means of these discourses, IS reworks foundational myths and traditional religious symbols to appropriate an imagined past in a highly charged political and conflict-ridden context as a part of the solution to its beleaguered spirituality. This proposal suggests employing interdisciplinary methods: critical discourse analysis (CDA), Corpus Linguistics, visual content analysis and multi-modal analysis. This aims to examine discourse, content and visual frames. The sample is supposed to include all YouTube video clips published by IS and the commentaries associated with these clips in English and Arabic. The importance of this project lies in understanding the socio-political and cultural-religious dimensions of the conflict and the ensemble of discourses that frame Islamic fundamentalism in general, and IS in particular, as well as how IS persuades recruits from the EU and worldwide. This project is significant in opening a new academic career path for me and in giving me an opportunity to apply for professorship/senior lecturer and chair positions in media and communication, sociolinguistics and discourse of Islamist movements in future.";195454,8;195454,8;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;UNIVERSITY OF NEWCASTLE UPON TYNE;UK;;;;1;0;0;1;0;0 206982;716461;SOCIALBOND;SIGNED;H2020-EU.1.1.;ERC-2016-STG;H2020;Social integration and boundary making in adolescence;2017-02-01;2022-01-31;;"The idea of boundary making has moved to the centre of influential agendas in immigration research. While many studies show the location and meaning of ethnic boundaries to vary across contexts, the conditions under which actors pursue different strategies of boundary making and produce different configurations of boundaries remain largely unknown. A major reason is the lack of a contextual unit of analysis that allows one to look at a large number of comparable social fields in which processes of boundary making unfold. My project is based on the idea that studying peer dynamics across a large number of schools constitutes strategic research material for understanding boundary making. I aim to develop a theory of boundary making that explains which combinations of attributes tend to become the basis of peer group affiliation and identities depending on school context. Realising this agenda has recently become possible through advances in multilevel longitudinal social network analysis and the collection of unique panel data on complete networks of over 18,000 students in more than 900 Dutch, English, German, and Swedish classrooms in 2010 and 2011. In order to investigate how the current influx of refugees transforms the configurations of boundaries, I will strategically complement this data by conducting a new three-wave panel study in one third of the original German schools. As part of this data collection, I will conduct the first smartphone-based experience sampling study on adolescents’ everyday boundary work, which allows me to capture its everyday salience as well as the impact of public discourse and political events. Aside from breaking new ground in the interdisciplinary fields of boundaries studies, immigration research, and network science, my project will potentially have an important social impact by identifying new factors that support or hinder the social integration of minority students.";1489916;1489916;ERC-2016-STG;/ERC-STG;UNIVERSITAET ZU KOELN;DE;;;;1;0;0;1;0;0 205488;721456;PATHSENSE;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2016;H2020;Training Network to Understand and Exploit Mechanisms of Sensory Perception in Bacteria;2017-04-01;2021-03-31;;"The PATHSENSE (Pathogen Sensing) ETN will bring together an interdisciplinary team of world-leading researchers from Europe to tackle a highly ambitious scientific project, focusing on the molecular mechanisms of sensory perception in bacterial pathogens. PATHSENSE will establish an innovative doctoral training programme that will deliver 13 PhD graduates and high-impact scientific outputs. The relationship between molecular structures and biological function is central to understanding any living system; however the research methodologies required to unravel these relationships are often complex and fast-changing. The team participating in this Network has the infrastructure and track-record to train ESRs in these state-of-the art methodologies, including structural biology, proteomics & protein biochemistry, molecular biology, bacterial genetics, food microbiology, mathematical modelling, cell biology, microscopy and comparative genomics. PATHSENSE will investigate the poorly understood structure-function relationships that exist within a large multi-protein complex called a “stressosome”, which acts as a sensory organelle in bacteria. The project will involve extensive inter-sectoral mobility of the ESRs across 7 EU countries to make full use of the complementary skills available at each of the hosting institutions. The inter-sectoral Network comprises 8 leading Universities, 1 public research institution, 4 companies (from spin-off to large multi-national) and 1 governmental agency. A major objective of this Network will be to exploit the fundamental research to develop novel antimicrobial treatments that have applications in the food and public health sectors. This project will deliver high-impact science, 13 highly-trained innovative researchers and will produce a long-lasting inter-sectoral network of collaborators who will continue to work together to exploit fundamental research for the socio-economic benefit of Europe.";3385026,36;3385026,36;H2020-MSCA-ITN-2016;/MSCA-ITN-ETN;NATIONAL UNIVERSITY OF IRELAND GALWAY;IE;"UNIVERSITAET REGENSBURG;NESTEC SA;NIZO FOOD RESEARCH BV;THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;UNIVERSITY OF DUNDEE;UNIVERSITY OF NEWCASTLE UPON TYNE;NATAC BIOTECH SL;AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS;UMEA UNIVERSITET;RIJKSUNIVERSITEIT GRONINGEN;ERNST-MORITZ-ARNDT-UNIVERSITÄT GREIFSWALD";"DE;CH;NL;UK;ES;SE";;1;0;0;1;0;0 205335;700867;Pod Yield;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-GF;H2020;“Can bean yield losses caused by drought, heat stress and climate change be ameliorated by enhancing pod-specific stomatal conductance?”;2017-06-12;2020-08-31;;CO2-induced climate change is causing global warming and droughts, resulting in crop yield losses. Common bean (Phaseolus vulgaris) is among the most important food crops worldwide, but is very vulnerable to heat- and drought-induced yield losses. The key objective of this project is to experimentally test the potential for increased pod transpiration to enhance bean pod yield under climate-change-associated drought and heat stress. I will fill an empirical void by, for the first time, testing this critical hypothesis in (1) naturally drought- and heat- tolerant tepary bean (Phaseolus acutifolius) using transcriptomic analysis, and (2) by transgenic enhancement of pod-specific stomatal conductance in the stress-intolerant common bean (P. vulgaris). For comparative transcriptomic analysis of Phaseolus pod drought and heat responses I will be trained in RNAseq, and for transgenic experiments I will produce stable Phaseolus transformants and characterise pod water flux by cutting-edge terahertz spectroscopy during the out-going phase in the lab of Prof. Covarrubias at the Institute of Biotechnology, National Autonomous University of Mexico (IBT-UNAM). I have designed a soybean promoter-driven construct that will direct expression of a dominant Arabidopsis allele to enhance Phaseolus pod stomatal opening and this will be compatible for use in many legume crops. To transfer this important agri-tech innovation back to Europe, I will characterise tepary bean and the transgenic plant’s growth and yield responses to a Future Climate Change Scenario during the return phase at the beneficiary, the University of Sheffield (USFD). At the USFD the group of Prof. Gray has unique expertise in stomatal and guard cell responses to elevated [CO2] and combines infrared thermography and infrared-gas analysis to phenotype whole-plant CO2 growth responses. The project uses an interdisciplinary and translational approach to tackle food security issues under climate change.;237493,8;237493,8;H2020-MSCA-IF-2015;/MSCA-IF-GF;THE UNIVERSITY OF SHEFFIELD;UK;;;;1;0;0;1;0;0 206957;715097;EVOMICROCOMM;SIGNED;H2020-EU.1.1.;ERC-2016-STG;H2020;Evolving interactions in microbial communities;2017-05-01;2022-04-30;;"Microbes play an important role in various aspects of our lives, from our own health to the health of our environment. In almost all of their natural habitats, microbes live in dense communities composed of different strains and species that interact with each other. As these microbes evolve, so do the interactions between them, which alters the functioning of the community as a whole. In this project, I propose to develop theoretical and experimental tools to study and control evolving interactions between cells and species living in microbial ecosystems. This will involve three main research objectives: first, we will couple theory and experiments to disentangle and characterise the social interactions between five bacterial species that make up an ecosystem used to degrade pollutants. Our second objective will be to use this knowledge to control this same ecosystem, by directing it toward increased productivity and stability. Finally, our third objective will be to “breed” novel communities from scratch using experimental evolution to promote cooperative interactions between community members and thereby increase productivity. This interdisciplinary and ambitious research will allow us to improve existing methods in pollution degradation, and to design new microbial communities for this and other purposes. More generally, our model system will provide an in-depth conceptual understanding of microbial ecosystems and their evolution, and the tools to investigate more complex microbial communities. My ultimate vision is to possess the technology to use microbial communities to degrade waste, generate efficient biofuels, and design customised treatments for intestinal diseases. This project promises to create the foundations needed to develop this technology, and open many exciting avenues for future research.";1498875;1498875;ERC-2016-STG;/ERC-STG;UNIVERSITE DE LAUSANNE;CH;;;;1;0;0;1;0;0 206507;731976;MAGENTA;SIGNED;H2020-EU.1.2.2.;FETPROACT-01-2016;H2020;MAGnetic nanoparticle based liquid ENergy materials for Thermoelectric device Applications;2017-01-01;2020-12-31;https://www.magenta-h2020.eu/;"MAGENTA proposes a brand new technological path in thermoelectric materials research for waste-heat recovery applications. The originality of the project is based on the newly discovered thermal-to-electric energy conversion capacity of ionic-liquids and ferrofluids; i.e., colloidal dispersions of magnetic nanoparticles in ionic liquids (IL-FFs). It is an inter-disciplinary and cross-sector R&D project combining concepts and techniques from physics, chemistry and electrochemistry with an active participation from 3 SME and 1 industrial partners implicated in the materials supply-chain, the device design/performance and the market-uptake assessment. Both experimental and theoretical approaches will be employed to build foundational knowledge on novel magneto-thermoelectric phenomena in ferrofluids. Computational simulations will allow ‘bottom-up’ construction of IL-FFs with optimal conditions for harvesting energy. The end-products of MAGENTA, application specific magneto-thermoelectric materials and devices, will provide innovation leadership to European companies in waste-heat recovery industries. The lead-user industries targeted by MAGENTA are automobile and microelectronic sectors, but demonstration-type thermoelectric generators will also be produced for public outreach actions on waste-heat recovery technologies. Through its foundational, interdisciplinary and cross-sector research & innovation actions, the consortium will become a “seed community” for building an innovation ecosystem around the novel magneto-thermoelectric technology, presenting long-term impacts on future renewal energy science and technology from which the society as a whole can benefit. Withal, MAGENTA offers breakthrough thermoelectric materials that are versatile, cost-effective and non-toxic to assist the economically and environmentally sustainable energy transition in Europe.";4999778,75;4999777,5;FETPROACT-2016;/RIA;COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES;FR;"SOLVIONIC;CENTRO RICERCHE FIAT SCPA;CONSIGLIO NAZIONALE DELLE RICERCHE;""NATIONAL CENTER FOR SCIENTIFIC RESEARCH """"DEMOKRITOS"""""";GEMMATE TECHNOLOGIES SRL;HAUTE ECOLE SPECIALISEE DE SUISSE OCCIDENTALE;C-TECH INNOVATION LIMITED;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;POLITECHNIKA GDANSKA";"FR;IT;EL;CH;UK;PL";;1;0;0;1;0;0 206920;704786;3D-Plant2Cells;TERMINATED;H2020-EU.1.3.2.;MSCA-IF-2015-GF;H2020;Exploring the Impact of Pesticide on the 3D Metabolome and the Microbiota from the Whole Plant to the Cell Scale;2017-01-01;2019-12-31;;The project 3D-Plant2Cells proposes to explore the impact of the agricultural mode on crops grown for human consumption. We are going to develop innovative interdisciplinary approaches to study the metabolome and the microbiota of plants in three-dimension (3D) at three different scales: the whole plant, the fruit, and the cellular scales. The objective of this study is to get a new insight on the metabolome and microbiota response to pesticide treatment. The hypothesis is that the chemistry and microbiome could change upon the use of conventional cultivation managements. To explore this hypothesis, two groups of plants will be cultivated in growth chamber and one will received pesticide treatments. Then, we will use an innovative interdisplinary approach to explore the entire pool of metabolite (metabolome) and the plant-associated commensal microbes (plant microbiota) on the whole plant surface (plant scale). Samples will be collected on the whole plant and their metabolite content will be profiled by high-resolution tandem-mass spectrometry (HR-MS/MS) and plant-associated micro-organism communities by amplicon sequence analysis. Results of these both inputs will be uploaded into a bioinformatic model representing a 3D topological map of the metabolome/microbiome over the entire organism surface. In a second part of the research project, we will study fruits of the cultivated specimens by 3D mass spectrometry imaging. The goals are to visualize, in a spatially-resolved way, the metabolome/microbiota response to pesticide treatments along with the pesticide distribution in 3D. The metabolome will be investigated at two scales: the fruit and the cell. The fruit scale will be explored by analyzing serial sections using matrix assisted laser desorption ionization (MALDI) or nanodesorption electrospray ionization (nanoDESI) .... The entire project will be an important contribution to assess the impact of pesticide on plant metabolome/microbiome and on food safety.;246668,4;246668,4;H2020-MSCA-IF-2015;/MSCA-IF-GF;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FR;;;;1;0;0;1;0;0 204787;692671;TRAIN-HEAL-TH;SIGNED;H2020-EU.1.1.;ERC-PoC-2015;H2020;Empowering expectations for health and disease: Development of a pioneering training tool;2016-08-01;2018-01-31;;"Expectations about health and disease are known to directly affect health and treatment outcomes. In the EXPECT-HEALTH project, my research group is unravelling the central mechanisms of how expectations affect immune and endocrine responses and related health outcomes, through the use of pioneering multidisciplinary methods in healthy and clinical populations. Ultimate goal of gaining this knowledge is to apply it in innovative therapeutic interventions. In order to reach this goal, an innovative multimodal training tool based on the dual expectancy learning approach (including implicit and explicit processes) proposed in the EXPECT-HEAL-TH project will be developed and brought to the pre-demonstration phase, making optimal use of new technology including implicit and explicit methods in the area of eHealth and serious gaming. I propose this proof of concept, termed TRAIN-HEAL-TH, to facilitate the design and development process in 4 stages: 1) development of innovative training tools, 2) usability and functionality testing of multimodal training tools, 3) pilot feasibility testing of multimodal training tools in relevant target populations and improving training tools based on pilot testing, and 4) evaluation of potential commercialisation opportunities. This interdisciplinary, cross-boundary project aims to design a training tool that can be applied in healthy as well as clinical populations. The development process, including potential professional commercialisation opportunities, will be facilitated and evaluated in this study using state of the art knowledge within the field of eHealth and serious gaming. The project will result in a multimodal training tool that may be tailored to individual target populations for disease prevention and improvement of health outcomes. For the first time, the theoretical underpinnings of EXPECT-HEAL-TH are translated into innovative therapeutic tools that have potential for a broad range of societal and economic benefits.";150000;150000;ERC-2015-PoC;/ERC-POC;UNIVERSITEIT LEIDEN;NL;;;;1;0;0;1;0;0 203849;707042;ROUFER;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Eighteenth-century republicanism and the critique of commercial society: the case of Rousseau and Ferguson;2017-03-01;2019-02-28;;"The project’s key assumption is that Rousseau and Ferguson offer a distinctive “partisan-republican” perspective. More strongly than fellow-republicans like Montesquieu, Hume and Smith, they focus on commercial society’s corrupting effects, concluding that the only remedy is a recovery of traditional civic virtues. Objectives 1. The project fills a major lacuna in Enlightenment historiography: the strong kinship between Ferguson and Rousseau is evident, but no sustained comparative study exists. 2. The project forms a significant contribution to the debate on the (dis)continuities in the republican tradition and its relation to the natural law tradition. 3. A joint reading of Rousseau and Ferguson vis-?-vis the debate on virtue and commerce sharpens and modifies our insight in this debate. They express most uncompromisingly the worries that also plague Smith, Montesquieu and Hume. Hence, the project demonstrates that Rousseau and Ferguson are no outdated Romantics in a general discourse of optimism. Method The comparative historico-philosophical method has an interdisciplinary character: the project’s focus on intellectual and socio-economic contexts relates it closely to intellectual history and economics. The comparative methodology allows the project to transcend dichotomies between Continental and Anglo-Saxon scholarship. Expected results: 4 peer-reviewed articles. 1 popular article. 1 conference. Impact -Through participation in international workshops and publication of articles in high-impact journals, the researcher gains an excellent academic standing. -The opportunity offered at Lausanne to connect with researchers in various countries gives the researcher a broad European profile and enhances his network. -By working in a competitive team, he sharpens his linguistic, cooperative and argumentative skills -Through various public engagement activities (public lectures; blogs; popular article) his research is disseminated beyond the academic world.";175419,6;175419,6;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;UNIVERSITE DE LAUSANNE;CH;;;;1;0;0;1;0;0 204719;681346;REALISM;SIGNED;H2020-EU.1.1.;ERC-CoG-2015;H2020;Reproducing EArthquakes in the Laboratory: Imaging, Speed and Mineralogy;2016-10-01;2021-09-30;;"We propose a simple idea: to reproduce earthquakes in the laboratory. Because earthquakes are spectacular examples of uncontrollable catastrophes, the opportunity to study them under controlled conditions in the laboratory is unique and is, in fact, the only way to understand the details of the earthquake source physics. The aim of the project is interdisciplinary, at the frontiers between Rock Fracture Mechanics, Seismology, and Mineralogy. Its ultimate goal is to improve, on the basis of integrated experimental data, our understanding of the earthquake source physics. We have already shown that both deep and shallow laboratory earthquakes are not mere `analogs’ of earthquakes, but are real events – though very small [Passel?gue et al. 2013, Schubnel et al. 2013]. During laboratory earthquakes, by measuring all of the physical quantities related to the rupturing process, we will unravel what controls the rupture speed, rupture arrest, the earthquake rupture energy budget, as well as the common role played by mineralogy in both shallow and deep earthquakes. We will also perform some experiments on rock samples drilled from actual active fault zones. Our work will provide insights for earthquake hazard mitigation, constrain ubiquitously observed seismological statistical laws (Omori, Gutenberg-Richter) and produce unprecedented data sets on rock fracture dynamics at in-situ conditions to test seismic slip inversion and dynamic rupture modelling techniques. The new infrastructure we plan to install will reproduce the temperatures and pressures at depths where earthquakes occur in the crust as well as in the upper mantle of the Earth, with never achieved spatio-temporal imaging resolution to this day. This will be a valuable research asset for the European community, as it will eventually open the door to a better understanding of all the processes happening under stress within the first hundreds of kilometres of the Earth.";2748188;2748188;ERC-2015-CoG;/ERC-COG;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FR;;;;1;0;0;1;0;0 204747;682859;SHAPE;SIGNED;H2020-EU.1.1.;ERC-CoG-2015;H2020;Shape Understanding: On the Perception of Growth, Form and Process;2016-08-01;2021-07-31;;"Whenever we look at an object, we can effortlessly infer many of its physical and functional properties from its shape and our previous experience with other objects. We can judge whether it is flexible or fragile; stable or likely to tumble; what might have happened to it in the past (e.g. a crushed can or bitten apple); and can even imagine how other members of the same object class might look. These high-level inferences are evidence of sophisticated visual and cognitive processes that derive behaviorally significant information about objects from their 3D shape—a process we call 'Shape Understanding'. Despite its obvious importance to everyday life, practically nothing is known about how the brain uses shape to infer the properties, origin or behavior of objects. The goal of this project is to develop a radically new interdisciplinary field to uncover how the brain 'makes sense of shape'. We suggest that when we view novel objects, the brain uses perceptual organization mechanisms to infer a primitive 'generative model' describing the processes that gave the shape its key characteristics. We seek to identify the psychological and computational processes that enable the brain to parse and interpret shape this way. To achieve this, we unite ideas and methods from surface perception, morphogenesis, geometry, computer graphics, na?ve physics and concept learning. We will simulate physical processes that create and modify 3D forms (e.g. biological growth, fluid flow, ductile fracture). We will use the resulting shapes as stimuli in experiments in which observers must identify key shape features, recognize transformations that have been applied to shapes, or predict the likely shape of other exemplars from the same object class. We will then model subjects' performance by geometrically analyzing shapes to find cues to the underlying shape-forming processes. These cues will be combined to infer generative models using inference techniques from machine learning.";1950725;1950725;ERC-2015-CoG;/ERC-COG;JUSTUS-LIEBIG-UNIVERSITAET GIESSEN;DE;;;;1;0;0;1;0;0 204691;676832;TagIt;SIGNED;H2020-EU.1.1.;ERC-StG-2015;H2020;A Minimal-Tag Bioorthogonal Labelling Approach to Protein Uptake, Traffic and Delivery;2016-10-01;2021-09-30;;The ability to probe dynamic cellular events that involve disease-associated proteins is limited, to a large extent, by the lack of development of a strategy that can use small coupling partners to react in chemoselective fashion with rapid kinetics that does not interfere with biological function(s) and localisation. In this application, I describe a conceptually new bioorthogonal-labelling approach that combines the introduction of a minimal non-canonical amino acid with chemoselective reactions, which display rapid kinetics, to label proteins in live cells. The small size of the new alkene-tagged amino acids, which will be genetically encoded, should not interfere with the protein’s innate structure, function(s) or localisation. Site-selective bioorthogonal labelling will be achieved through the use of a new photo-triggered [2\2] cycloaddition reaction with an alkene-bearing fluorophore and the known inverse-electron-demand Diels-Alder reaction with a fluorogenic tetrazine. Although the former offers potentially improved spatial and temporal resolution, the latter allows for turn-on fluorescence. The proposed new methodology will be applied in the context of a key cytokine involved in cancer progression. The ability to label this cytokine with minimal perturbation of its structure, function(s) and localisation will enable monitoring of its internalisation and intracellular trafficking pathways in cells that overexpress its receptor. In doing so, new insight into cancer biology will be generated that will inform the construction of safer, selective and more efficient protein-drug conjugates for targeted cancer treatment. The concept proposed here is designed to be generally applicable to label and study disease-associated proteins that are difficult to access by means of conventional protein-labelling methods and constitute the first integrated, interdisciplinary approach for the development of protein drug-conjugates.;1499106;1499106;ERC-2015-STG;/ERC-STG;THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;UK;;;;1;0;0;1;0;0 204741;682451;SEXHUM;SIGNED;H2020-EU.1.1.;ERC-CoG-2015;H2020;Sexual Humanitarianism: understanding agency and exploitation in the global sex industry;2016-10-01;2020-09-30;;"The humanitarian fight against trafficking in the sex industry legitimizes the enforcement of increasingly restrictive migration laws and controls, which often exacerbate sex workers’ vulnerability to being trafficked. SEXHUM adopts an art-science interdisciplinary approach bringing together visual anthropology, sociology, gender and queer studies and human geography to study the relationship between migration, sex work, exploitation and trafficking. It contextualizes this relationship within the global onset of sexual humanitarianism, a concept coined by the PI. It refers to the ways migrants are increasingly represented, understood and targeted by the media, policymakers and social interventions as vulnerable to exploitation and abuse in relation to their sexual orientation or behaviour. SEXHUM adopts a migration studies perspective and a participative approach to focus on migrant sex workers addressed by sexual humanitarianism as victims of trafficking. It reappraises the concepts of exploitation, slavery and trafficking through the lens of how they are understood and experienced by migrants. The project analyses the global emergence of humanitarian migration governance by examining the impact of sexual humanitarianism across six strategic urban settings in Europe (France – Marseille and Paris), the US (New York and Los Angeles), Australia (Sydney) and New Zealand (Auckland) that are characterized by different policies on migration, sex work (criminalisation, regulation, de-criminalisation) and trafficking. The innovative method developed by the PI combines ethnographic observations, semi-structured interviewing and participative filmmaking to address the narrated as well as the affective, relational and performative dimensions of migrants’ experiences of agency and exploitation. The research will generate needed user-based data on the impact of anti-trafficking initiatives that will be highly relevant to policymaking.";1600000;1600000;ERC-2015-CoG;/ERC-COG;KINGSTON UNIVERSITY HIGHER EDUCATION CORPORATION;UK;UNIVERSITE D'AIX MARSEILLE;FR;;1;0;0;1;0;0 204702;678341;USECFrontiers;SIGNED;H2020-EU.1.1.;ERC-StG-2015;H2020;Frontiers of Usable Security – Principles and Methods for Administrator and Developer Usable Security Research;2016-08-01;2021-07-31;;"Usability problems are a major cause of many of today’s IT-security incidents. Security systems are often too complicated, time-consuming, and error prone. For more than a decade researchers in the domain of usable security (USEC) have attempted to combat these problems by conducting interdisciplinary research focusing on the root causes of the problems and on the creation of usable security mechanisms. While major improvements have been made, to date USEC research has focused almost entirely on the non-expert end-user. However, many of the most catastrophic security incidents were not caused by end-users, but by developers or administrators. Heartbleed and Shellshock were both caused by single developers yet had global consequences. The recent Sony hack compromised an entire multi-national IT-infrastructure and misappropriated over 100 TB of data, unnoticed. Fundamentally, every software vulnerability and misconfigured system is caused by developers or administrators making mistakes, but very little research has been done into the underlying causalities and possible mitigation strategies. I aim to extend the frontiers of usable security by conducting foundational research into USEC methods for developers and administrators. To this end I will research and systemize the hitherto unexamined human factors in a carefully selected set of problems currently faced by developers and administrators, specifically: authentication, secure messaging, systems configuration, intrusion detection, and public key infrastructures. From this pioneering research I will extract and develop principles, methods, and best practices for conducting usability studies and research with these actors and establish a foundation for this emerging research field. In addition to these foundational methodological results, I expect to make fundamental advancements in the above application research domains by including the human factors in these currently purely technical research areas.";1498976;1498976;ERC-2015-STG;/ERC-STG;RHEINISCHE FRIEDRICH-WILHELMS-UNIVERSITAT BONN;DE;;;;1;0;0;1;0;0 204527;705334;DisWildPop;TERMINATED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Impacts of Diseases on Wild Bird Populations;2017-03-01;2019-02-28;;Understanding what makes organisms ill, and the implications of diseases for dynamics and persistence of wild populations are receiving increased attention from epidemiologists, animal and public health scientists and evolutionary biologists since diseases have major impacts on human and non-human populations. Here I propose a research that capitalizes from recent advances in disease identification, demographic modelling and advanced phylogenetic comparative analyses to investigate the links between pathogen prevalence and life histories, demography and social behaviour of hosts. Using birds as model organisms, first I propose to investigate how prevalence of major causative agents of disease vary across taxa with variable patterns of life history, ecology and social behaviour. Second, I aim to investigate whether prevalence of a wide range of pathogens differ between males and females, and whether these differences result from the distinct roles they play in reproduction. Finally, I will examine whether sex differences in pathogen prevalence predict sex-specific mortality and biased sex ratios. To achieve these Objectives, I will integrate data and methodology from wildlife disease biology, behavioural ecology and population demography. The Fellowship will enhance my analytic skills and provide training in three major fields: disease biology, comparative phylogenetic analyses and population demography. The Do?ana Biological Station (Spain) will provide a unique opportunity to acquire these skills en route to address the project Objectives, and excellent prospects for career development and interdisciplinary collaborations. In addition, the proposed project will have knock-on benefits for biodiversity conservation by providing key knowledge on the capacities of wild birds to respond to disease threats across diverse ecosystems.;170121,6;170121,6;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS;ES;;;;1;0;0;1;0;0 204920;703737;FemEcoMig;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Uneven lives: female economy, migration patterns and citizenship in Early Modern Italy;2017-05-01;2019-07-14;;"FemEcoMig aims to study the connections between migration patterns and female property, work and social networks in Early Modern Italy: it focuses on domestic and international migrations and on female migrants (and their families) who moved to the duchy of Savoy-Piedmont during the period 1650-1800. The project aims to change the common narrative on the history of migration by bringing into the topic a range of historiographical problems that are often considered characteristic of the history of women. It will inquire into the role women's paid and unpaid work and into the use of female property in settlement paths; it will also tackle the extent of female social networks and their use to access to urban resources. The second objective is to analyse the connections between female migration and the achievement of naturalisation. This section will investigates foreign women applying for naturalisation and the reasons for their application. The project will tackle the contents of the grant, and the conditions in which citizenship was enacted and will inquire into the links between migration and settlement paths, economic activities and family strategies. Data will be collected at the National Archives in Turin: two databases will be set up (one for female migrants, the second for people asking for naturalisation), and a sample of migrants drawn from the databases will be the object of biographical reconstruction in notarial deeds. The research will be conducted at the History Faculty of Cambridge University and at the Cambridge Group for the History of Population & Social Structure. The candidate will receive high level and interdisciplinary training to improve skills in data analysis. She will benefit from the host's organisation experience, discuss the qualitative and quantitive analysis of data, the methodological approach and the historiographical problems with the supervisor and other specialists, and improved competence in migration history and women history.";195454,8;195454,8;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;UK;;;;1;0;0;1;0;0 204882;695528;MSG;SIGNED;H2020-EU.1.1.;ERC-ADG-2015;H2020;Making Sense of Games: A Methodology for Humanistic Game Analysis;2016-11-01;2021-10-31;;"Making Sense of Games (MSG) will build a methodology for the humanistic study of games, and develop a theory of how ludic meaning is produced. Following the pervasive, global growth of video gaming culture and the games industry, the multi-disciplinary field of game studies has grown exponentially in the last 15 years, with numerous new journals, conferences, university programs and research departments. However, still lacking at this ‘adolescent’ stage of the field’s development are game-specific methods and theoretical foundations necessary to train researchers and build curricula. In aesthetic games research there is not yet any widely accepted methodology for game analysis, and there has not yet been any large-scale, long-term attempt to produce a theoretical platform that can support and advance the field. MSG aims to fill this gap by combining fundamental hermeneutic approaches (semiotics, reception theory, reader response, theories of representation, narrative theory) with recent theories of ludic structure (game ontology) into a hermeneutic theory of game meaning, which can be used as a set of tools and concepts for game analysis and criticism. MSG will be a triple first for aesthetic game research: a five-year research program, a hermeneutic theory of games, and a team-based effort to build an interdisciplinary methodology. The results from MSG will speak to many of the current public concerns and debates about games, such as gamer culture, games’ cultural and artistic status, the representation of minorities, misogyny, violence and even addiction. MSG will demonstrate the strong usefulness of humanistic approaches not only to game studies itself, but also to the 21st century’s most vibrant new cultural sector. It will also provide other aesthetic fields (literary studies, film studies, art history) with theoretical models, critical insights, and a rich empirical material for comparative exploration.";2006905,94;2006905,94;ERC-2015-AdG;/ERC-ADG;IT-UNIVERSITETET I KOBENHAVN;DK;;;;1;0;0;1;0;0 204710;679000;MORALSELF;SIGNED;H2020-EU.1.1.;ERC-StG-2015;H2020;Unravelling the moral self;2016-09-01;2021-08-31;;"Philosophers and social scientists have emphasized that our moral self-concept, the degree to which being moral is central for us, plays a pivotal role in explaining humans’ tendency to act prosocially. Clarifying the development of the moral self-concept and discovering the functional mechanisms is thus central for clarifying the basis of human morality. Despite a set of perennial questions that the moral self-concept relates to and the empirically proven relevance, research has largely neglected the early ontogeny of the moral self-concept. This is all the more surprising as recent developmental research demonstrated a hitherto unknown inclination of young children to act prosocially, which has led to a theoretical reorientation in developmental science. Moreover, the neurocognitive basis of moral identity as well as the functional mechanisms that relate moral identity to prosocial behaviour have have yet to be discovered, leaving the ontogeny and the nature of the moral self-concept in the dark. In this proposal I will take a new approach by combining novel tools derived from developmental psychology and cognitive neuroscience to provide a comprehensive model of the moral self-concept that integrates (i) knowledge on the developmental origins and changes, (ii) its neurocognitive basis, and (iii) the functional mechanisms that relate the moral self-concept to actual prosocial behavior. To this end, the project relies on an interdisciplinary methodological approach by combining explicit interview measures, implicit attitudes tests, behavioral assessments, and electrophysiological methods with both children and adults to empirically explore the human moral self-concept. The current project not only contributes to a perennial debate on the origins of human morality; providing knowledge on the factors that promote the moral self-concept will also have societal impact by informing theory and practice of moral education.";1498958;1498958;ERC-2015-STG;/ERC-STG;LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN;DE;;;;1;0;0;1;0;0 204733;682077;APOLOGY;SIGNED;H2020-EU.1.1.;ERC-CoG-2015;H2020;Political Apologies across Cultures;2016-09-01;2021-08-31;;In the past decades, there has been a considerable rise in the number of apologies offered by states for injustices and human rights violations. Among transitional justice scholars, there is significant debate about how useful such apologies are. Whereas some have applauded these gestures as an important step in peacemaking processes, others have argued that they may not fit in all cultures and may even be a risky tool for peacemaking. Unfortunately, theorizing and research in the field of transitional justice is still in its infancy and has not systematically addressed questions of cross-cultural variability yet. So, at present, we do not know whether political apologies are a universally viable way to restore justice and harmony. My project addresses this challenge. Using an innovative, interdisciplinary, and multi-method approach with in-depth interviews, (experimental) surveys, and content analyses of apologies, I analyze whether there are universals in how political apologies are valued, expressed, and interpreted or whether this varies as a function of cross-cultural differences in key values (collectivism and individualism) and norms (face and honor). Based on these findings, I build a theoretical framework that will fundamentally advance our understanding of the potential value and role of apologies in transitional justice processes. This project breaks new ground because it is the first to take the difficult step to collect cross-cultural data to examine whether key assumptions regarding political apologies hold across cultures. It is also the first in this area to use a multi-method approach, which makes it possible to take into account the complex reality of political apologies. Combining insights from transitional justice, cross-cultural psychology and anthropology, this project places theorizing on transitional justice on a much firmer footing and paves the way to more cross-culturally valid models to restore justice and promote reconciliation.;1917713;1917713;ERC-2015-CoG;/ERC-COG;STICHTING KATHOLIEKE UNIVERSITEIT BRABANT;NL;;;;1;0;0;1;0;0 203372;682001;BoneImplant;SIGNED;H2020-EU.1.1.;ERC-CoG-2015;H2020;Monitoring bone healing around endosseous implants: from multiscale modeling to the patient’s bed;2016-10-01;2021-09-30;;"Implants are often employed in orthopaedic and dental surgeries. However, risks of failure, which are difficult to anticipate, are still experienced and may have dramatic consequences. Failures are due to degraded bone remodeling at the bone-implant interface, a multiscale phenomenon of an interdisciplinary nature which remains poorly understood. The objective of BoneImplant is to provide a better understanding of the multiscale and multitime mechanisms at work at the bone-implant interface. To do so, BoneImplant aims at studying the evolution of the biomechanical properties of bone tissue around an implant during the remodeling process. A methodology involving combined in vivo, in vitro and in silico approaches is proposed. New modeling approaches will be developed in close synergy with the experiments. Molecular dynamic computations will be used to understand fluid flow in nanoscopic cavities, a phenomenon determining bone healing process. Generalized continuum theories will be necessary to model bone tissue due to the important strain field around implants. Isogeometric mortar formulation will allow to simulate the bone-implant interface in a stable and efficient manner. In vivo experiments realized under standardized conditions will be realized on the basis of feasibility studies. A multimodality and multi-physical experimental approach will be carried out to assess the biomechanical properties of newly formed bone tissue as a function of the implant environment. The experimental approach aims at estimating the effective adhesion energy and the potentiality of quantitative ultrasound imaging to assess different biomechanical properties of the interface. Results will be used to design effective loading clinical procedures of implants and to optimize implant conception, leading to the development of therapeutic and diagnostic techniques. The development of quantitative ultrasonic techniques to monitor implant stability has a potential for industrial transfer.";1992154;1992154;ERC-2015-CoG;/ERC-COG;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FR;;;;1;0;0;1;0;0 204735;682125;MAPLE;SIGNED;H2020-EU.1.1.;ERC-CoG-2015;H2020;Measuring and Analysing the Politicisation of Europe before and after the Eurozone Crisis;2016-08-01;2021-07-31;;The Eurozone crisis forces us to reconsider the conventional wisdom that “Europe” has little effect on national electoral politics. MAPLE’s central goal is to analyse the degree of politicisation the European issue has acquired following the Eurozone crisis, in Belgium, Germany, Greece, Ireland, Portugal and Spain in 2000-2016, and to focus on its consequences for voting behaviour. Our main thesis is that a fundamental shift has occurred in the vote function as a result of this politicisation: short-term factors of voting behaviour, such as economic perceptions as well as leader effects may have been structurally diminished in the countries which have seen bailouts and where citizens increasingly perceive the main policy decisions being directed from Brussels. To measure politicisation of the EU we will analyse both parliamentary debates and media outlets coding for salience and polarisation of the European issue. These measurements will contribute to understand how politicisation of the EU has underpinned political changes between 2000 and 2016 in the countries concerned. The analysis of voting behaviour will employ a social-psychological methodology in order to test the relationship between increased politicisation of the EU and short-term effects. MAPLE will create datasets for 12 newspapers, more than 60 political parties, 26 elections as well as conduct 12 web panel surveys of a representative sample of voters in the countries concerned. MAPLE is interdisciplinary: it combines approaches from social psychology and political science. It includes qualitative data collection (coding of newspapers and parliamentary debates) followed by qualitative and quantitative data analysis. MAPLE will ultimately illuminate the way in which Europe has decisively entered national electoral politics and with what consequences for the vote calculus.;1592859;1592859;ERC-2015-CoG;/ERC-COG;INSTITUTO DE CIENCIAS SOCIAIS;PT;;;;1;0;0;1;0;0 204133;682549;VIREX;SIGNED;H2020-EU.1.1.;ERC-CoG-2015;H2020;Mumps VIRus EXploitation of the human adhesion receptor GPR125;2016-07-01;2021-06-30;;"Mumps virus is a re-emerging pathogen that causes painful inflammatory symptoms, such as parotitis (salivary gland infection) and orchitis (testis infection). It is highly neurotropic with evidence of brain infection in half of cases and clinical evidence in up to 10%. It is a small RNA virus belonging to the family of paramyxoviridae that includes e.g. viruses for measles and pneumonia, all having a huge impact on global economics and human health. Current vaccine programs have not managed to eliminate mumps and infections occur also in vaccinated individuals. Seven transmembrane (7TM) receptors are important drug targets. Large DNA viruses (herpes- and pox-) assign large parts of their genomes to exploit 7TM receptors. No such mechanism has however yet been described for small viruses. Based on strong preliminary data, I will in this interdisciplinary project test the groundbreaking hypothesis that the adhesion 7TM receptor GPR125 is central for the organ damage caused by mumps virus via an interaction with the mumps virus-encoded short-hydrophobic (SH)-protein. I will do so by determining: 1 - The functional consequences of GPR125-SH-interaction at a single cell, organ and whole body level within the context of mumps virus infection 2 - The structural requirements for the GPR125-mumps virus interaction using NMR and resolution of crystal structure in preparation for future drug design The project is high risk and high gain, yet the gain clearly exceeds the risk. On account of my past expertise in pharmacology and virology, and that of several expert collaborators, the project is indeed feasible. It has tremendous perspectives as SH-proteins are present also in other viruses. The SH-GPR125 complex might thus represent a general principle for organ damage and a mode of action more generally amenable to therapeutic interference. In fact, novel approaches, mechanism-based, might be seen as more appealing to those who fear current vaccination 'modes'.";1813367;1813367;ERC-2015-CoG;/ERC-COG;KOBENHAVNS UNIVERSITET;DK;;;;1;0;0;1;0;0 203443;701584;MinimalSelf;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Embodiment, Intersubjectivity, and the Minimal Self;2016-07-01;2018-06-30;;"The proposed project is a philosophical and interdisciplinary study of the most fundamental sense of self. It will take, as its starting point, the concept of “minimal self”, as recently employed by philosophers such as Gallagher and Zahavi. The aim of the project is to develop a clearer, more elaborate, and substantially revised conception of minimal self. First of all, I will engage in depth with relevant phenomenological scholarship, focusing on the work of Husserl and Merleau-Ponty. I will then use the results of this engagement to critically discuss, elaborate and revise current conceptions of minimal self. Finally, I will examine applications of the concept of “minimal self” in psychiatry and psychopathology, for instance by Parnas et al. and Sass. The project will be structured around three guiding questions, to which others have given conflicting or insufficiently clear answers: 1. Is the minimal self given in experience, or is it a formal abstraction from experience? 2. Is the minimal self prior to intersubjectivity, or is it inextricably intertwined with intersubjectivity? 3. In what sense is the minimal self 'embodied', and how does this relate to the issue of intersubjectivity? I will argue that the minimal self is integral to experience rather than an abstraction from it. Furthermore, it is inextricable from interpersonal experience, to an extent that others, such as Zahavi (2014), have not sufficiently acknowledged. I will also make clear how the intersubjective structure of minimal self relates to its bodily nature. This view will be supported through a detailed study of the phenomenology of self-disturbances such as schizophrenia, and I will show how the revised concept of minimal self has significant implications for our understanding of psychopathological disturbances.";166156,8;166156,8;H2020-MSCA-IF-2015;/MSCA-IF-EF-RI;UNIVERSITAT WIEN;AT;;;;1;0;0;1;0;0 203282;694202;LHCDMTOP;SIGNED;H2020-EU.1.1.;ERC-ADG-2015;H2020;Novel Dark Matter Searches with Top Quarks at the Large Hadron Collider;2016-05-01;2020-04-30;;This project will address directly the two most important unanswered questions in particle physics: the Standard Model (SM) hierarchy problem and the nature of dark matter (DM). The SM was recently completed with the discovery of the Higgs boson at the Large Hadron Collider (LHC) in 2012. We know, however, that the SM cannot be the end of the story for fundamental physics, because it suffers from two major flaws: a lack of stability for the mass of the Higgs boson (the hierarchy problem), and a lack of a candidate for the invisible DM particles known to make up most of the matter in the universe. I will address both of these key problems of modern physics by searching at the LHC for new beyond the SM (BSM) partner states for the SM top quark decaying to new DM particles. The greatly increased quantities of data and world-record collision energies generated by the LHC in the next three years will provide an unprecedented opportunity to find such top partners. Confirmation of their existence would solve the hierarchy problem by providing a mechanism for stabilising the mass of the Higgs boson, while first observation of DM at the LHC would revolutionise our understanding of cosmology and provide a key pointer to the physics of the very early universe. Many leading BSM physics models predict the existence of both top partners and DM, and so this interdisciplinary project provides a unique opportunity to take the next major step forward in developing a unified theory of nature. I will focus on top partners which decay to a top quark and a DM particle, with the former decaying purely to jets and the latter escaping the detector unseen. I will use novel kinematic techniques developed by me to identify and characterise this signal in LHC data, and also accurately measure for the first time the dominant SM background process of associated production of top quarks and a Z boson, which is of great theoretical interest in its own right.;1584650;1584650;ERC-2015-AdG;/ERC-ADG;THE UNIVERSITY OF SHEFFIELD;UK;;;;1;0;0;1;0;0 203183;713654;Career-FIT;SIGNED;H2020-EU.1.3.4.;MSCA-COFUND-2015-FP;H2020;Career Development Fellowships in the National Technology Centre Programme;2017-01-01;2021-12-31;;Career-FIT is a new trans-national scheme that offers an opportunity for experienced researchers to develop their careers n market focused applied research in Ireland's Technology Centres. Covering a wide range of academic and industry areas aligned with Ireland's Smart Specialisation Strategy, the 15 Centres were established to encourage greater efficiency in the interaction between researchers, industry, and the public sector, in research that promotes economic growth by its direct relevance to industry agendas. Each multidisciplinary Centre offers excellent facilities and equipment for Fellow use: experienced scientific staff to support the Fellow’s research, and extensive enterprise relationships on which market focused applied research can be progressed. Following two widely publicised calls that seek to attract the highest quality researchers with their own research proposals, the Career-FIT programme offers 50 fellowships of 36 months’ duration for incoming mobility to the Centre Hosts, with an enterprise secondment option during the Fellowship. Selection is through a transparent process based on demonstrated excellence of the applicant, potential of the research programme, host organisation capacity to provide a developmental environment, and training/career development impact of the Fellowship. Fellows are mentored by an experienced Centre mentor(s) concerned not just for their scientific progress but also their training and development in line with agreed career goals. They will also have support from a Professional Development Advisor and will further benefit from participation in a structured development training programme that targets enhancement of personal effectiveness as well as competencies relating to innovation management. As a new programme offering interdisciplinary, intersectoral and international features, the Career-FIT human resource development objectives will guarantee the development of future research and innovation leaders.;10620000;5310000;H2020-MSCA-COFUND-2015;/MSCA-COFUND-FP;ENTERPRISE IRELAND;IE;;;;1;0;0;1;0;0 201530;707593;EARTHSCAPES;TERMINATED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;From Landscapes to Earthscapes: Understanding Visual Cultures of Global Environmental Crisis and the Making of Global Environmental Images, 1945-present (EARTHSCAPES);2017-09-01;2019-08-31;;"From Landscapes to Earthscapes: Understanding Visual Cultures of Global Environmental Crisis and the Making of Global Environmental Images, 1945-present (EARTHSCAPES) EARTHSCAPES will contribute to current debates on the origins and possible futures of the environmental crisis by providing an innovative historical, social and political perspective on the production, circulation and reception of global environmental images since the beginning of the Cold War. It will further our understanding of the role of images in science by means of a thorough historical, political and sociological analysis of case studies, focusing on visualisations that allow for a global interpretation and understanding of our environment (hence the term “global environmental images”). The images concerned by this project help communicate global and a priori invisible environmental phenomena (global temperature, ozone levels, sea-level rise, climate change, etc.). By making the invisible visible, global environmental images reveal to be always both, the very tools that enable scientists to understand complex environmental and geophysical processes, and the instruments that allow them to share their findings with decision makers and the larger public. Images fulfil therefore always two functions; they are both: objects and instruments of knowledge. Yet few studies have explored in detail this double function, allowing to understand how global environmental processes are visually produced, represented, rendered evident, and consumed. Hence, a historically informed interdisciplinary study is urgently needed, also because the past may hold crucial answers for the future. EARTHSCAPES main aim is to close the research gap by analysing how iconic paintings, photographs, maps, graphs, visualisations and remote sensing images profoundly shaped environmental discourse, and a holistic and dynamic understanding of the Earth system since the beginning of the Cold War.";185857,2;185857,2;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;KUNGLIGA TEKNISKA HOEGSKOLAN;SE;;;;1;0;0;1;0;0 202888;704537;DecodeRemapping;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Decoding the neural mechanism of human spatial cognition using behavioural and hemodynamic signals;2017-08-01;2019-07-31;;The aim of this research is to understand space constancy, that is the mechanisms used by the brain to build a stable and continuous percept of our environment despite frequent movements of our sensory receptors (eyes, ears). For example, each time we move our eyes, the image of the outside world sweeps across the retina, yet we see the world as stable. Studies using single cell recording in animals have shown that some visual neurones predict what the world will look like after an eye movement by remapping their receptive fields to the place they will occupy following the movement. In my previous studies I developed behavioural tools that allowed me to model remapping in human as an attentional process. Even though my findings in humans were largely consistent with the results obtained from single cell recordings in animals, there was no possible way to establish a direct link between these data. Recent methodological advances in functional imaging, both in terms of techniques and data analysis make this possible. By combining my tools with novel imaging analysis of human population receptive fields, I aim to determine the mechanisms our brains use to stabilise our percept of the world for visual and auditory objects. Using hemodynamic (fMRI) and behavioural (gaze recording) signals I will decode the organisation of the multi-sensory spatial maps. I aim to determine the role of attention for space constancy, to establish innovative methods and procedures for investigating human spatial cognition, and to reconcile human and animal neurosciences findings by providing precise neural information of the maps and the neural mechanisms of human spatial navigation. This interdisciplinary project will constitute a unique opportunity to combine my expertise with state-of-the-art methods. I will have the chance to expend my skills, putting me on the best track to pursue a future independent research career with a multi-faceted profile of psychologist and neuroscientist.;177598,8;177598,8;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;STICHTING VU;NL;;;;1;0;0;1;0;0 201371;705857;smartCC;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Designing novel smart sensor interfaces based on a biologically abundant peptide motif: coiled-coils;2017-06-01;2019-05-31;;Smart interfaces alter their properties in response to an external trigger. Such devices open exciting opportunities for novel technologies with manifold applications. Electrical fields pose easily controllable triggers for smart interfaces and even allow a precise 'digital' switching between 'on' and 'off' states. The research project ‘smartCC’ will employ a biologically abundant class of biomacromolecules – coiled-coil peptides – to prepare smart selective interfaces, whose ability to specifically bind targets can be switched reversibly. Moreover, the produced interface will constitute a highly sensitive sensor by application of the attenuated total reflection infrared reflection technique. The variability of coiled-coils, employed in numerous biological systems, will also extend the potential application bandwidth of smart interfaces significantly. Molecular details of the switching and binding behaviour of the coiled-coils at the interface will be studied to test the feasibility of the envisioned working principle. Furthermore, the novel devices will be tested for an application with industrial relevance. To reach the goals of ‘smartCC’ a highly interdisciplinary approach is chosen that includes cooperation between three academic and one non-academic European partners. Thus, the implementation of this project will support bringing an emerging technology towards an economical benefit, foster intra European collaborations and mobility as well as strengthen Europe’s scientific sector.;159460,8;159460,8;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;MAX PLANCK INSTITUT FUR EISENFORSCHUNG GMBH;DE;;;;1;0;0;1;0;0 201093;703009;Phenclass;TERMINATED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Ancient Philosophy and the Emergence of European Thought: Phenomenology in Conversation with Classical Studies;2016-09-01;2018-08-31;;Phenomenological thinkers (most notably E. Husserl, M. Heidegger, J. Patoèka, and J. Derrida) outlined influential philosophical perspectives on the ancient roots of European thought. The action’s aim is to provide a critical reassessment of those perspectives by developing an extensive comparative analysis between them and research done by prominent classicists, in particular W. Jaeger, B. Snell, J.-P. Vernant, G.E.R. Lloyd, and M. West. This comparative approach will take the following questions as reference framework: (1) How did ancient thought shape European identity? (2) How did the Greek roots of European thought interact with other sources of European culture? (3) Is there a connection between the much-debated crisis of Europe and the ancient roots of European culture? (4) Does the retrieval of the ancient roots of European culture play a role for the future of Europe? This design of the planned action implies five major innovations. (i) It is the first attempt to provide an extensive comparison between phenomenology and classical studies with a view to their respective readings of ancient thought. (ii) It is the first extensive attempt to discuss questions related to the ancient sources of European identity by addressing fascinating interdisciplinary intersections between phenomenology and classical studies. (iii) It is the first extensive attempt to challenge phenomenological readings of ancient thought by assessing them from an external viewpoint. (iv) It is the first extensive attempt to approach phenomenological conceptions of the ancient roots of Europe by avoiding a merely author-oriented approach and using a theme-oriented analysis. (v) Finally, the planned action is a concrete example of how contemporary societal, political, and cultural challenges, such as the question of European identity, can be approached by using academic scholarship, in this case two disciplines such as philosophy and classical studies.;158121,6;158121,6;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;UNIVERSIDAD CARLOS III DE MADRID;ES;;;;1;0;0;1;0;0 201368;705826;NanoOxySens;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Luminescent Polymer Nanoparticles with Aza-BODIPYs, Porphyrins and their Metal Complexes for FRET Mediated Ratiometric Oxygen Sensing;2017-05-15;2019-05-14;;"This proposed Fellowship brings together an Experienced Researcher from India with expertise in the synthesis of photosensitizers and their photophysical characterization, tuning the excited-state properties, investigation of their photophysics and photobiology with an internationally recognized Host Laboratory in France with expertise in designing fluorescent molecular and nanoparticle probes for bioimaging. This project will provide (i) interdisciplinary training of highest quality to become an outstanding scientist with excellent publication record; (ii) enhance European excellence in organic synthesis, nanosciences and biophotonics. The aim of the research project is to obtain ratiometric probes for molecular oxygen based on biodegradable polymeric nanoparticles (NPs) bearing far-red/near-infrared absorbing triplet sensitizers such as aza-BODIPYs, porphyrins and corresponding metal complexes. The project involves the synthesis of phosphorescent dyes (aza-BODIPY/porphyrins) and formulation of polymeric NPs encapsulating these dyes. The development of ultra-bright polymer nanoparticles, an innovative method recently discovered in the Host Laboratory, will enable the development of novel dual emissive polymeric NPs with the triplet sensitizers. In our design, fluorescent NPs excite triplet sensitizers through energy transfer (FRET), resulting in dual emission: fluorescence of NPs and phosphoresce of the sensitizer. Only phosphorescence of FRET acceptor is sensitive to molecular oxygen (3O2), which provides the mechanism of dual colour ratiometric response to oxygen. The approach will be further validated in solutions and in living cells. The obtained nanoprobes for oxygen will be applied to living cell and (in collaboration) to whole animals. It is our strong conviction that the possibilities of this multidisciplinary chemistry are enormous, and the end result will be the development of a simple nano-device for molecular oxygen build from biodegradable materials.";185076;185076;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;UNIVERSITE DE STRASBOURG;FR;;;;1;0;0;1;0;0 201363;705768;InviCitRom;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Invisible Edges of Citizenship: Re-addressing the position of Romani Minorities in Europe;2017-09-01;2019-08-31;;This research addresses the question why the position of Roma in Europe keeps deteriorating despite all the (inter)national efforts put into its improvement. Roma persist as the main targets of ethnic discrimination and are faced by severe socio-economic inequalities throughout Europe. This project recognizes the urgent need to readdress the position of Roma at the times, when most of the programmes for their integration are nearing its conclusion (such as the Decade for Roma Inclusion 2005-2015) and when their intra-European mobility is being particularly problematized. By employing interdisciplinary quantitative and qualitative methodology and theoretical conceptualizations from the perspective of citizenship studies, this project aims to offer a novel insight on the position of Roma in Europe. The project investigates different dimensions of citizenship (rights, dimensions, belonging) in order to show that Roma are not an exception or a minority that simply ‘does not fit’ and is hence excluded from society. I seek to develop a new theoretical perspective to support the above claim: I argue that there are certain institutional mechanisms, that I call as invisible edges of citizenship involved in the production of the marginalization of Romani minorities in all European states where they reside either as citizens or migrants. Instead of only offering selected case studies, this research aims to offer a cross-country comparative analysis of citizenship and minority acts as well as Roma National Strategies and the experience of Romani individuals themselves with the invisible edges of citizenship. The results of this research will be relevant both for academics as well as policy makers: I will prepare a cross-country database on approaches to minority protection and major challenges connected to the position of Roma, 2 journal articles and a book manuscript.;160800;160800;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;KATHOLIEKE UNIVERSITEIT LEUVEN;BE;;;;1;0;0;1;0;0 201238;704438;TICKLE ME;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Self and others in the sensorimotor system: a computational neuroanatomy of sensory attenuation;2017-01-01;2018-12-31;;"Why can’t you tickle yourself? Previous behavioural and neuroimaging evidence suggests that when we move one hand to touch the other, the resulting tactile sensation is perceived as less intense compared to identical touches of external origin. This sensory attenuation (SA) phenomenon is hypothesized to arise because our brains use internal information about the motor command (efference copy) to predict the tactile consequences of the movement and attenuate the tactile feedback based on these predictions. However, little is known about how the brain produces SA. ‘TICKLE ME’ combines, for the first time, computational motor control theory, force perception behavioural experiments, and state-of-the-art neuroimaging methods to address how the human brain distinguishes between self-generated and externally-generated touch. The project aims to: - Clarify the principal importance of voluntary motor commands, efference copy, and perceived physical contact of body parts in a series of behavioural experiments. - Identify the neuroanatomical network responsible for generating SA by using state-of-the-art functional magnetic resonance imaging. - Investigate how the brain learns to predict the sensory consequences of our actions by using error-driven learning mechanisms. - Develop a novel neurocomputational model of SA. The project will result in a synergy between the applicant’s highly interdisciplinary profile and the high quality of the host institution. The applicant has experience in different scientific areas such as experimental cognitive psychology, psychophysics, virtual reality, computational modeling and programming as well as a background in electrical engineering that makes her uniquely suited to carry out this project. Additionally, the Karolinska Institutet, the Department of Neuroscience, and in particular Prof. Henrik Ehrsson will provide valuable theoretical knowledge in sensorimotor control as well as technical expertise in neuroimaging in support of the project.";173857,2;173857,2;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;KAROLINSKA INSTITUTET;SE;;;;1;0;0;1;0;0 201479;707072;MARDIV;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;'Marriage and Cultural Diversity in the German Empire';2016-09-19;2019-09-18;;How do putatively universalistic norms with global reach relate to politics of diversity and pluralism within national societies? By assessing the legal regulation of marriage and the family, ‘Marriage and Cultural Diversity in the German Empire’ (MARDIV) will advance significantly our understanding of the global diffusion of legal and social norms. The tension between global norms and cultural specificity has come to a head during the first decade of the 21st century. Not only has the presence of Muslim immigrants raised the profile of debates over the diversity of personal status law throughout Europe. The legalisation of same-sex marriage in many European countries has also pointed to a seachange in public views about the family and the role of the state in preserving it. How do legal transplants operate in family law? Can we discern particular patterns of diffusion in specific historical circumstances? And, how do 19th- and early 20th-century developments in family law remain relevant today? MARDIV addresses these questions by scrutinizing the historical roots of recent debates. 19th- and early 20th-century Germany offers a particularly relevant case study because it was a laboratory of both modernity and cultural diversity in which questions of global reach, national identity, regional particularity and local traditions came into especially sharp relief. MARDIV suggests that an understanding of Germany’s past experiences can enable us to better analyse Europe’s present. To this end, the project employs an innovative interdisciplinary methodology linking history and sociology and a novel theoretical framework. The main empirical aims are twofold: to shed light on the historical roots of contemporary European debates about the family, and to reflect on broader processes of the global diffusion of legal and social norms. The primary aim is the PI’s advanced training in historical sociology and project management so she can reach a position of research leadership.;171460,8;171460,8;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;GEORG-AUGUST-UNIVERSITAT GOTTINGENSTIFTUNG OFFENTLICHEN RECHTS;DE;;;;1;0;0;1;0;0 202175;703352;EUICIT;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;EU Intersex Citizenship;2016-09-01;2018-08-31;;"The EUICIT action addresses the rights claims and agendas of intersex people and those with Disorders of Sexual Development (DSD), in response to recent Council of Europe recommendations to revise medical and policy approaches. The term 'Intersex' refers to people born with sex characteristics (chromosomal, gonadal and/or anatomical) not easily classifiable as either male or female; at least 1 person in 2000 is intersex/has DSD. Intersex/DSD people are a highly marginalised section of the EU population. Conflicts exist between those who seek to depathologise intersex and those who seek rights within the medical framework (DSD-oriented. There is a pressing need for research that highlights the experiences, understandings, and views of intersex/DSD people within a European context. In particular, an investigation of debates about intersex versus DSD perspectives is necessary, because of the divergent human rights and social policy implications of these two approaches. EUICIT is framed within interdisciplinary citizenship and participative democratic approaches, in order to highlight human rights issues, and to explore tensions between medical-oriented rights claims and those that seek depathologisation. It uses triangulated qualitative research methods: documentary and policy analysis across the EU, interviews with activists and healthcare/policy actors in Italy, the UK and Switzerland, and participant observation in a secondment organisation (Zwischengeschlecht- ZW). The case study countries were chosen to represent varied types of intersex/DSD activism and relationship to the EU. ZW, which is based in Switzerland, takes a combined medical/activist approach; it is actively engaged in policy work at national and international levels and is ideally suited to fieldwork on the topic. The project team has been assembled to help the applicant develop her existing expertise, drawing in expertise of gender theory, citizenship and human rights.";183454,8;183454,8;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;THE UNIVERSITY OF HUDDERSFIELD;UK;;;;1;0;0;1;0;0 203140;708601;PROPERA;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-GF;H2020;The Profanation of Opera: Music and Drama on Film;2017-03-01;2020-02-29;;The project PROPERA (The Profanation of Opera: Music and Drama on Film) aims to shed new light on the relationship between opera and film. It draws on the hypothesis that the mediation of film displaces, broadens, and enriches our experience and understanding of opera in ways that have not yet been fully explored in their aesthetic and political potential. To fill this gap, the proposed research on the interplay between the two genres and media over the last hundred years will focus on a variety of objects including not only opera-films, but also feature- and short-length mainstream and experimental movies that incorporate opera in relevant and thought-provoking ways. The ultimate goal of looking at opera through the lens of film is to develop and refine a “profane” approach to a “sacred” genre – that is, to challenge the identification of opera as a live performance art belonging to an inherently conservative tradition so as to reimagine the past, present, and future of the operatic genre in a media-saturated world. Based on an interdisciplinary approach at the crossroads of opera and film studies, musicology, and philosophy, the consequences of this shift of perspective will be explored from the standpoint of production and spectatorship, with regard to traditional and contemporary repertoire alike. Globally seen, the project – to be carried out at the University of Chicago and the Universidade Nova de Lisboa, but involving several non-academic institutions – also seeks to create bridges between scholarly research, artistic practice and public engagement. The outcomes include 1 monograph, at least 6 articles, 3 workshops, 1 international conference, 1 festival, 1 conference series, 1 collaborative on-line platform, and 1 international network on opera, film and new media. If successful, the project will have a considerable impact on the scientific career of the candidate and strongly contribute to the internationalization of the host institution.;234448,2;234448,2;H2020-MSCA-IF-2015;/MSCA-IF-GF;UNIVERSIDADE NOVA DE LISBOA;PT;;;;1;0;0;1;0;0 202925;705204;BIJOU;TERMINATED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Biomolecular Identification of Ornaments;2017-03-30;2019-03-29;;"Symbolic material culture and personal ornaments can be used as effective proxies for tracking mobility and identity in the past: prehistoric Europe was interconnected by a network of long-distance exchange routes of shell “jewellery”. The movements of ornaments can thus reveal contact between communities, elucidating cultural dynamics and patterns of migration. In the absence of written documents, reconstructing the journey of ornaments from their place of origin to their final destination requires secure information on the taxonomy and provenance of the shells. BIJOU will develop a novel interdisciplinary approach for shell ornament identification, advancing the traditional morphological methods and exploiting the biomolecules trapped in shells as taxonomic barcodes. Integrating six state-of-the-art techniques (proteomics and amino acid analyses, macro- and micro-morphology, mineralogy, stable isotopes) and focusing on fifteen key archaeological sites across Europe, BIJOU will build the first publicly available reference collection of shells, identify the materials used to make ornaments and determine their local or exotic provenance. This will provide the long-awaited scientific basis for theories on long-distance exchange in prehistory. Building on the complementary expertise of the Researcher (archaeology and ancient proteins) and the Host Institution (shell biominerals), BIJOU will deliver long-term scientific benefits, including an ad-hoc methodology for the investigation of precious artefacts, and the establishment of an international network of archaeologists. The wealth of information on the modes and tempos of interaction between peoples in the past will be the focus of public dissemination and will inform current debate on the fundamental right of freedom of movement and perceived loss of cultural identity, contributing to building a European society that is truly “inclusive, innovative and reflective” (Europe 2020 strategy).";185076;185076;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;UNIVERSITE DIJON BOURGOGNE;FR;;;;1;0;0;1;0;0 202762;702030;CIModelPLUS;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Advanced Computational Model for the Development of Cochlear Implants;2017-03-01;2019-02-28;;Cochlear implants (CIs) are proven effective in restoring hearing to the severe-to-profoundly deaf. Up to 2012, there were more than 100,000 CI users in Europe, which only accounts for 7% of all adult CI candidates. The most severe limitation of current CI technology is caused by the wide spread of electric current in the cochlea, which results in a poor spectral resolution of electrical stimulation of the nerve and limits the number of effective electrodes. Computational models of the cochlea have been used to facilitate the development of CIs. These models depend on the geometry of the reconstructed cochlea and the exact knowledge of the electrical impedances of different tissues. However, only crude estimation of the impedances of all media is available, and most computational models of the cochlea only adopted an ideal representation of the geometry. Therefore, CIModelPLUS aims to provide engineers an advanced computational model of the cochlea with incorporated CI, which will show improved accuracy of the electric current distribution in the tissues, in order to facilitate the development of next-generation CIs. To fulfil this aim, computational models of cochleae will be reconstructed from the µ-CT scans of temporal bone specimens, and the electric current distribution inside the cochlea will also be measured experimentally. The simulation and experimental results will later be combined to develop the advanced computational model of the cochlea. CIModelPLUS involves interdisciplinary research between engineering, physics, neuroscience and medicine, and intersectoral collaboration between academia and CI industry. It will lead to the future development of CIs due to the accurate and validated computational approach adopted, and the advancement of CI technology will improve the quality of life of over 100,000 current CI users and other CI candidates in Europe, as well as that of their families and the communities that they reside in.;159460,8;159460,8;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;TECHNISCHE UNIVERSITAET MUENCHEN;DE;;;;1;0;0;1;0;0 202612;683018;PALEODEM;SIGNED;H2020-EU.1.1.;ERC-CoG-2015;H2020;Late Glacial and Postglacial Population History and Cultural Transmission in Iberia (c.15,000-8,000 cal BP);2016-10-01;2021-09-30;;"The aim of this project is to investigate patterns of population history and cultural transmission from the Late Magdalenian to the Late Mesolithic (c.15,000-8,000 cal BP) in South-western Europe. This period witnessed major environmental changes and cultural transformations on settlement distribution, technology and social organisation. Our project specifically addresses two major inter-related research topics: Firstly, to what extent demographic behaviour was driven by environmental factors; and secondly, how did regional population patterns influence cultural transmission processes. This project develops a new, multi-scale, methodological approach to study population patterns and cultural change between the Late Magdalenian and the Late Mesolithic in the Iberian Peninsula. First, at a local scale, our project will combine new empirical data obtained at open-air residential sites with well dated multi-proxy palaeoenvironmental reconstructions to understand the impact of climate change and hydrological stress on human settlement areas. Then, we will reconstruct population patterns at 4 different Iberian regional units analysing summed probabilities of radiocarbon date distributions from a new audited radiocarbon database. Finally, we will conduct computational network analysis at a macro-regional scale to identify how diachronic variations on hunter-gatherer settlement networks affected the transmission of cultural traits and the spread of technological innovations. With this multi-step interdisciplinary approach, we aim to provide a chronological-secure framework and spatially explicit context for the interpretation of population history, cultural change, and resilience to environmental changes through from the Late Pleistocene-Early Holocene transition to the Middle Holocene in Iberia.";1460385;1460385;ERC-2015-CoG;/ERC-COG;FUNDACIO PRIVADA INSTITUT CATALA DE PALEOECOLOGIA HUMANA I EVOLUCIO SOCIAL;ES;;;;1;0;0;1;0;0 202595;682167;VIBRANT-BIO;SIGNED;H2020-EU.1.1.;ERC-CoG-2015;H2020;High-throughput vibrational fingerprinting by nanoplasmonics for disease biology;2017-01-01;2021-12-31;;"Devastating diseases such as Alzheimer’s, Parkinson’s and various cancers are still without cures, continue to undermine the quality of life for millions of people and impose significant economic burdens. Misfolded toxic proteins constitute the microscopic basis of these diseases, but little is understood about their structure and biological function. This is due the fact that current technologies are severely limited for molecular-level identification of protein structures and high-throughput analysis of biomolecular interactions. VIBRANT-BIO aims to introduce breakthrough mid-infrared spectroscopy technologies, including the first spectroscopic microarray, to overcome the limitations of current methods by enabling complete profiling of biomolecules from identification of their structure and composition to their biological function. To achieve its ambitious goals, VIBRANT-BIO will exploit plasmonics and newly discovered two-dimensional nanomaterials such as graphene and explore the ultimate limits of light-matter interaction to demonstrate biosensors with extreme sensitivity, throughput and functionality, well beyond the state-of the art. It will innovatively integrate nanoplasmonics with advanced photonics and bioanalytical tools to dramatically enhance sensor performance and introduce new functionalities. The proposed technologies will be applied to study toxic amyloid-beta proteins and their interaction with lipid membranes for understanding the molecular mechanisms underlying Alzheimer’s disease. VIBRANT-BIO will contribute to define the road-map for next generation biosensor and spectroscopy technologies through interdisciplinary research covering physics, engineering, chemistry and biology. The capability of the proposed systems to analyze a broad range and ultra-low quantities of molecules and chemicals provides a general-purpose toolkit that can impact numerous fields such as bioscience, material science, pharmaceutical industry, and homeland security.";2562325;2562325;ERC-2015-CoG;/ERC-COG;ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE;CH;;;;1;0;0;1;0;0 203059;706888;GenderJust;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Truth and Reconciliation Commissions and the Political Economy of Gender Justice: Discursive Power, Authority and the Subaltern;2017-08-01;2019-07-31;;"This project aims to better understand how Truth and Reconciliation Commissions (TRCs) shape and legitimize international norms on gender justice and how local contexts respond to these norms. While many research projects have focused on the way domestic powerful actors and institutions actively reconstruct new norms to make them fit their own cognitive prior (Acharya 2009; Wiener 2009), the extent to which marginalised actors, such as women victims or victim survivors of mass atrocities, experience and respond to international norms directed to them remains largely unexplored. I consider the cases of South Africa, Rwanda and Colombia. The first objective is to examine the variability of inclusion of gender justice narratives in the TRCs proceedings and policy formulation. I attempt to do this by analysing institutional inputs and networks of actors (Mackay, Kenny and Chappell 2010). The second objective is to understand the role of female witnesses and women collectives in shaping accepted narratives on gender justice (Krizsan and Lombardo 2013). This project is a continuation of the candidate's previous research on local contestation and adaptation of international norms in post-conflict settings. For so doing, the project will follow a qualitative analysis based on TRCs transcripts and semi-structured interviews with strategic groups, providing original empirical evidence of this unexplored level. Data collection will take place during monthly mobilities to each of the countries. These data will then be analysed following grounded theory techniques and critical discourse analysis. The research will be conducted at the Department of Politics and International Studies at the University of Cambridge where the candidate will receive high level training to improve her methodological skills (qualitative data analysis and theory producion) and will greatly benefit from the host organisation's experience in interdisciplinary research on international norms.";195454,8;195454,8;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;UK;;;;1;0;0;1;0;0 202978;706283;VORTSHEET;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Vortex sheets - from new intuitions to crucial questions.;2017-01-01;2018-12-31;;"Understanding fundamental phenomena in fluid mechanics, such as formation of vortices at wingtips of a plane taking off or development of repetitive turbulent patterns of clouds, requires studying special flows which are characterized by a jump of velocity across certain interfaces. These singular flows correspond to solutions of the classical Euler equations from inviscid fluid dynamics, called vortex sheets. Remarkably, the existence and uniqueness of vortex sheets remain outstanding open problems even though they are of vital importance in applications in aerodynamics and climatology. We aim to approach these problems from a new point of view and thus contribute to the development of the area. To achieve our goals we will - construct a new family of vortex sheets called 'vortex cusps', - study singularities, which vortex cusps may develop, - study related models to gain further intuitions. The project will be conducted at the University of Warwick under the supervision of a leading researcher in the field, J.L. Rodrigo. It will also include a secondment in Seville, hosted by F. Gancedo and short visits to other experts in the field (D. Cordoba, Ch. Fefferman, T.Cieslak). This setup guarantees the highest quality of academic training, which will significantly broaden the previous interdisciplinary expertise of G. Jamroz (who finished his PhD in Warsaw in January 2015 and is currently a postdoc in Basel) and will, in combination with an intensive transferable skills training, lead him to an independent researcher position. What is more, the project will strengthen the position of the University of Warwick as a top mathematical research centre by extending its network of collaborations across Europe. The results of the research will be actively and frequently communicated both to experts and general public by open-access and peer-reviewed publications as well as conferences and general public events, thus ensuring maximum outreach of the proposed action.";195454,8;195454,8;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;THE UNIVERSITY OF WARWICK;UK;;;;1;0;0;1;0;0 203087;707537;MAPS-URBE;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-GF;H2020;The invisible city. Mapuche mapping of Santiago de Chile.;2017-03-01;2020-02-29;;The proposed research explores experiences of urban space among young indigenous Mapuche living in Santiago de Chile, in order to make visible indigenous subjects whose daily lives, collective concerns and social circumstances are often relegated to the margins of policy making and public interest. It seeks to research the impact of displacement and social exclusion on indigenous youth, as well as offer a means of intervention. The project will identify a set of mutually negotiated research aims alongside young Mapuche, developing a series of collaborative and participatory methods, including mapping, video and exhibition making, to offer a better understanding of indigenous experiences of the city as a kind of “in betweeness” - as expressed by the term Mapurbe, from mapu (earth) and urbe (city) - used to symbolize the on-going negotiation of marginality and displacement from the ancestral territory. The outcome of the collaborative research will be used to address the relationship with non-Mapuche citizens through two exhibitions (in Chile and Europe), offering young Mapuche an opportunity to make an active intervention into public discourse. The proposed research thus aims to apply theoretical knowledge, collaborative methods and modes of representation to issues of critical social interest in ways that are directly applicable to other context within Latin America and across Europe. The necessary training-through-research will be at the Instituto de Estudios Urbanos y Territoriales - Pontificia Universidad Católica (Chile), and at the Granada Centre for Visual Anthropology - University of Manchester (UK). This will provide the researcher with theoretical and technical competencies in Urban Studies and Visual Anthropology. The proposed research will contribute to the strengthening of European networking at an interdisciplinary and inter-continental level, building an international dialogue that will have positive and practical impacts on the European Research Area.;233811;233811;H2020-MSCA-IF-2015;/MSCA-IF-GF;THE UNIVERSITY OF MANCHESTER;UK;;;;1;0;0;1;0;0 199768;669690;CIVILWARS;SIGNED;H2020-EU.1.1.;ERC-ADG-2014;H2020;Social Dynamics of Civil Wars;2016-01-01;2020-12-31;;"Each year, civil wars cause hundreds of thousands of deaths, millions of refugees, ecological disruptions, regional instability. These conflicts encompass many players and their effects are felt not only at the regional level but also within Western societies (refugees, terrorism, sectarian tensions). Despite this, no systematic comparison of civil wars have been conducted using a qualitative method. Social scientists are struggling to understand these breakdowns of the social order, which are fertile from a theoretical perspective because they de-trivialize the social functioning. In civil war, the partial or total institutional collapse marks the end of the (imperfect) monopoly of the state with regards to violence and justice, challenges the social and ethnic hierarchies and also provokes fluctuation of the economic and social capital. Accordingly, we will address three questions. First, the sudden and non-anticipated reconfiguration of modes of accumulation and conversion of capitals and the relationship between social fields. Next, the formation of competing institutions by politico-military movements involved in the construction of an alternative political order. Finally, individual adaptations to risks and uncertainty affecting the ability of actors to anticipate the consequences of their actions and reassess their own values and engagement. The implementation of this program of comparative sociology of civil wars will draw on extensive fieldwork. This requires an adapted methodology for researchers faced with unpredictable situations, where quantitative methods fall short. Prosopography, semi- or unstructured interviews and participant observation are therefore prioritised. The creation of an interdisciplinary team of sociologists, political scientists and anthropologists will be able to carry out research based on thick description, following 25 years of experience by the PI in collecting data and supervising researchers in areas afflicted by civi";2500000;2500000;ERC-2014-ADG;/ERC-ADG;UNIVERSITE PARIS I PANTHEON-SORBONNE;FR;;;;1;0;0;1;0;0 199626;680275;MALIG;SIGNED;H2020-EU.1.1.;ERC-StG-2015;H2020;A mathematical approach to the liquid-glass transition: kinetically constrained models, cellular automata and mixed order phase transitions;2016-09-01;2021-08-31;;"This proposal focuses on the mathematics of three cross-disciplinary, very active and deeply interlaced research themes: interacting particle systems with kinetic constraints, bootstrap percolation cellular automata and mixed order phase transitions. These topics belong to the fertile area of mathematics at the intersection of probability and mathematical statistical mechanics. They are also extremely important in physics. Indeed they are intimately connected to the fundamental problem of understanding the liquid-glass transition, one of the longstanding open questions in condensed matter physics. The funding of this project will allow the PI to lead a highly qualified team with complementary expertise. Such a diversity will allow a novel, interdisciplinary and potentially groundbreaking approach. Even if research on each one of the above topics has been lately quite lively, very few exchanges and little cross-fertilization occurred among them. One of our main goals is to overcome the barriers among the three different research communities and to explore the interfaces of these yet unconnected fields. We will open two novel and challenging chapters in the mathematics of interacting particle systems and cellular automata: interacting particle glassy systems and bootstrap percolation models with mixed order critical and discontinuous transitions. In order to achieve our groundbreaking goals we will have to go well beyond the present mathematical knowledge. We believe that the novel concepts and the unconventional approaches that we will develop will have a deep impact also in other areas including combinatorics, theory of randomized algorithms and complex systems. The scientific background and expertise of the PI, with original and groundbreaking contributions in each of the above topics and with a broad and clearcut vision of the mathematics of the proposed research as well as of the fundamental physical questions,make the PI the ideal leader of this project.";883250;883250;ERC-2015-STG;/ERC-STG;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FR;;;;1;0;0;1;0;0 200586;703860;SOLARACT;TERMINATED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Solar Dinitrogen Activation;2016-04-01;2018-03-31;;"SolarAct aims at a fundamental theoretical understanding of transition metal catalysts that mediate the photochemical bond cleavage of the dinitrogen molecule. The efficient activation of dinitrogen (N2) as an abundant and thus very cheap resource is a promising target for the development of sustainable chemistry, e.g. to produce NH3 as a “solar fuel” or synthesize value-added products relevant for chemical industry. A new approach in N2 activation is the photolytic N-N bond cleavage in linear M-N-N-M complexes, for which five synthetic examples are known. However, the dynamical processes inducing N-N cleavage in these complexes after light excitation are not understood at a molecular level. SolarAct is the first research project to unravel the working principles of the existing N2 photoactivation catalysts using a combination of ab initio excited state dynamics simulations and multiconfigurational quantum chemistry methods. The project will push the boundaries of excited state dynamics simulations and provide a proof of principle for their application to dimeric transition metal complexes with demanding electronic structures. The key requirements for N2 photocleavage will be rationalized by systematic in silico variations of the known systems, culminating in improved N2 photoactivation catalysts according to a design target formulated for SolarAct. The researcher will transfer expertise in computational transition metal chemistry and theoretical spectroscopy to the host group and will gain expertise in novel methods for static and dynamic chemistry problems. A cross-sectorial and interdisciplinary workshop will increase the researcher's and host's networks. The researcher will emerge from SolarAct fully qualified for an independent career, including a unique, highly competitive research profile, enhanced presentation proficiency, optimal teaching and management skills, a wide scientific network and a breadth of dissemination and public engagement experiences.";166156,8;166156,8;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;UNIVERSITAT WIEN;AT;;;;1;0;0;1;0;0 200406;708257;FIREFELM;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Mastering the energetic particle distribution in a magnetohydrodynamic active plasma;2017-08-01;2019-08-31;;FIREFELM – fast ions, radial electric field and edge localized mode – is an interdisciplinary project aimed at getting a better understanding of the basic mechanisms responsible for the energetic particle transport in fusion as well as in astrophysical plasmas making use of advanced diagnostic systems and state-of-the-art numerical tools. The main goal of this proposal is to control the dynamics between energetic particles, radial electric fields and magnetohydrodynamic (MHD) perturbations in the plasma edge and its impact on the overall plasma confinement. The mechanisms underlying the fast ion transport induced by MHD instabilities, such as Edge Localized Modes (ELMs) and externally applied Magnetic Perturbations (MPs) will be studied through innovative diagnosis techniques developed at the University of Seville and the Centro Nacional de Aceleradores (CNA) in Seville, Spain and employed in different fusion devices such as ASDEX Upgrade (Germany) and MAST Upgrade (UK). This project consists of three main research lines which follow a bottom up approach: the first research line is dedicated to fusion technology and aims at the development of the new generation of fast ion loss detectors (FILDs). New FILD systems will be able to provide absolute fluxes of escaping ions, their poloidal distribution and critical information on the wave-particle momentum and energy exchange. These advanced FILDs will be employed to characterize the interdependence between fast ion losses and radial electric fields and to study the role of fast ions in plasma edge stability and in the ELM cycle. Unraveling the interaction between MHD instabilities and energetic particles in tokamak plasmas will advance our understanding of the observed particle acceleration and transport in the solar corona and help to identify similarities between tokamak and astrophysical plasmas. This third research line will shed light on the anomalous heating of the solar corona and generation of the solar wind.;158121,6;158121,6;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;UNIVERSIDAD DE SEVILLA;ES;;;;1;0;0;1;0;0 198641;648768;NEURIMMUNE;SIGNED;H2020-EU.1.1.;ERC-CoG-2014;H2020;Neural regulation of immunity;2015-10-01;2020-09-30;;"Survival of living organisms depends on their capacity to develop defence mechanisms against environmental challenges that cause tissue damage and infections. These protective functions involve the nervous system and the immune system, two systems traditionally considered as independent. However anatomical and cellular bases for bidirectional interactions between them have been established and a new paradigm on a regulatory role of the nervous system on immune functions is emerging. Pain is one of the major signs of inflammation. Upon acute injury, inflammation or infections noxious signals are perceived by nociceptors present in tissues, such as the skin. These sensory neurons convey the damaging information to the brain and release a number of mediators locally that could modulate immunity. The goal of this project is to decipher the functional role of sensory neurons and pain sensitivity on immune responses. We will tackle this highly challenging question by studying the immune responses to vaccination in genetic mouse models in which skin innervation by nociceptors is deficient. Our preliminary results are very promising as we already demonstrated that deficits in sensory skin innervation affect both the innate and adaptive immune responses to intradermal vaccine. We will further study the cellular and molecular mechanisms involved in this local and systemic modulation of the immune response by the nervous system. As a complementary approach, we will address the role of an exacerbated pain response on immunity through the selective stimulation of nociceptive neurons in wild type animals. This interdisciplinary study is designed to provide new insights into how the nervous system instructs the immune system. Results from NEURIMMUNE are expected to open new avenues of research on the integrated host response to pathogens with important implications for the design of innovative prophylactic vaccines and therapies.";2000000;2000000;ERC-2014-CoG;/ERC-COG;INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE;FR;;;;1;0;0;1;0;0 195917;660255;AMIABLE;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Advanced MIcroscopy of Attine ant BacteriaL Endosymbionts;2015-09-01;2017-08-31;;"Summary Most animals crucially depend on bacterial symbionts for digesting food and for optimal health, and such associations are particularly relevant for farming societies that produce their own food. Next to humans, the fungus-growing ants have realized the largest and most complex animal societies on Earth and also these societies depend on the services of multiple bacterial symbionts. The experienced researcher is a cell biologist with state-of-the-art training in electron microscopy who teamed up with the Copenhagen Centre for Social Evolution (CSE) to realize a uniquely interdisciplinary research program of microbial symbiosis. She focuses on three abundant gut bacteria of fungus-growing ants that were recently discovered by the host group, and which appear to function as nutritional and disease resistance mutualists in this complex symbiosis that has become one of the best-studied model systems of social evolution. The objectives of this project are: 1. To reconstruct the acquisition process of symbiotic bacteria during development of individual leaf-cutting ants; 2. To resolve structural adaptations of the bacteria for intracellular versus extracellular lifestyles. Neither of these objectives have been addressed before and both have high potential to change the way in which biologists think about bacterial symbioses. The project includes training-through-research of the researcher in molecular biology, bioinformatics and evolutionary theory, and considerable knowledge transfer in advanced microscopy from the researcher to the CSE host group. The project has been initiated with CSE funding, proven to be very synergistic and highly feasible, and the researcher has already built a collaborative network in Copenhagen. The present application seeks to realize the project’s full implementation, allowing the European Research Area to harvest the full benefits of the pioneering work already initiated.";200194,8;200194,8;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;KOBENHAVNS UNIVERSITET;DK;;;;1;0;0;1;0;0 197281;659079;HighTPSAFM;TERMINATED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;High throughput spectroscopy atomic force microscopy for the foot printing of bacteria and cellular organelle;2016-05-01;2018-04-30;;The project HighTPSAFM (High throughput spectroscopy atomic force microscopy for the foot printing of bacteria and cellular organelle) intends to develop and implement high throughput and high resolution modes of atomic force microscopy (AFM) with spectroscopy-like capabilities and enhanced sensitivity to detect and identify heterogeneous compositional contrast. The aim is to develop the instrumentation in order to answer and elucidate mechanisms of timely questions in molecular and cell biology, i.e. related to the Histone Code Hypothesis and bacterial resistance. Unresolved requirements involve simultaneously be minimally invasive while providing high throughput, high resolution and spectroscopic capabilities, such as chemical identification, or footprinting in the case of bacteria, cells and other biological systems, with high sensitivity. The applicant has already gained international recognition for his achievements in the field and become an emerging scientist of note. The project further represents a significant advance in the applicants’ career by expanding it towards applications in the fields of biotechnology and complementary optical techniques. The project will establish the candidate, and collaborators, in the field by building a European interdisciplinary and international team of growing stature and recognition. The project includes the building of a competitive network of collaborators in Europe with partners that will jointly serve to support and systematically fulfil the objectives. The two year project will further provide sufficient experience to the candidate as an independent researcher while being supported by an international referent in nanotechnology with state of the art infrastructure and facilities at of the Universidad de Murcia UM (CIOyN, Spain) and at Linz (JKU, Austria) as secondment. These have proven experience in the development and translation of microscopy instrumentation and new acquisition and data processing techniques.;170121,6;170121,6;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;UNIVERSIDAD DE MURCIA;ES;;;;1;0;0;1;0;0 197511;654761;BIOXYARN;TERMINATED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;In vitro evaluation of the biocompatibility of nanofibrous yarns from an oxidative stress perspective;2015-12-01;2017-11-30;;'Fibres and textiles have been used as biomaterials for thousands of years, mainly as sutures and in dressings for wound care. Recently, it has become of increasing interest to use fibres as implantable materials to support the repair of damaged tissues and organs. In particular, the emergence of nanoscale electrospun fibres has allowed the fabrication of scaffolds that mimic the architecture of native biological tissues. Many studies have demonstrated that these biomimetic nanofibrous materials have the ability to promote cell adhesion, proliferation, and differentiation. However, mixed results have been observed in vivo with regards to their biological effects, including the inflammatory response. Therefore, there is a strong need to understand better the mechanisms involved in the cell response to nanofibres and to come up with better in vitro models for predicting the biocompatibility of electrospun materials in vivo. In tissue healing processes, oxidative stress has been identified as one of the key pathophysiological elements. Therefore, this project will evaluate the biocompatibility of electrospun yarns, a new and promising generation of electrospun materials, from an oxidative stress perspective. Human fibroblasts will be grown on the materials under standard and induced oxidative stress conditions. The cell response to the materials will be assessed, in particular in respect to the induction of 4-hydroxynonenal, a major bioactive marker of lipid peroxidation known as the 'second messenger of free radicals'. Particular attention will be given to the effects of material degradation and of added antioxidants on the onset of oxidative stress. This interdisciplinary project will contribute to understand the mechanisms underlying interactions between cells and nanofibres that occur upon implantation. Additionally, it will guide the development of electrospun yarns with improved biocompatibility and will aid to evaluate the risks associated to their implantation.';170010;170010;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;RUDER BOSKOVIC INSTITUTE;HR;;;;1;0;0;1;0;0 202544;677448;CureCKDHeart;SIGNED;H2020-EU.1.1.;ERC-StG-2015;H2020;Targeting perivascular myofibroblast progenitors to treat cardiac fibrosis and heart failure in chronic kidney disease;2016-05-01;2021-04-30;;"Chronic kidney disease (CKD) is a growing public health problem with a massively increased cardiovascular mortality. Patients with advanced CKD mostly die from sudden cardiac death and recurrent heart failure due to premature cardiac aging with hypertrophy, fibrosis, and capillary rarefaction. I have recently identified the long sought key cardiac myofibroblast progenitor population, an emerging breakthrough that carries the potential to develop novel targeted therapeutics. Genetic ablation of these Gli1\ perivascular progenitors ameliorates fibrosis, cardiac hypertrophy and rescues left-ventricular function. I propose that Gli1\ cells are critically involved in all major pathophysiologic changes in cardiac aging and uremic cardiomyopathy including fibrosis, hypertrophy and capillary rarefaction. I will perform state of the art genetic fate tracing, ablation and in vivo CRISPR/Cas9 genome editing experiments to untangle their complex mechanism of activation and communication with endothelial cells and cardiomyocytes promoting fibrosis, capillary rarefaction, cardiac hypertrophy and heart failure. To identify novel druggable targets I will utilize new mouse models that allow comparative transcript and proteasome profiling assays of these critical myofibroblast precusors in homeostasis, aging and premature aging in CKD. Novel assays with immortalized cardiac Gli1\ cells will allow high throughput screens to identify uremia associated factors of cell activation and inhibitory compounds to facilitate the development of novel therapeutics. This ambitious interdisciplinary project requires the expertise of chemists, physiologists, biomedical researchers and physician scientists to develop novel targeted therapies in cardiac remodeling during aging and CKD. The passion that drives this project results from a simple emerging hypothesis: It is possible to treat heart failure and sudden cardiac death in aging and CKD by targeting perivascular myofibroblast progenitors.";1497888;1497888;ERC-2015-STG;/ERC-STG;UNIVERSITAETSKLINIKUM AACHEN;DE;;;;1;0;0;1;0;0 196875;648609;TWORAINS;SIGNED;H2020-EU.1.1.;ERC-CoG-2014;H2020;Winter Rain, Summer Rain: Adaptation, Climate Change, Resilience and the Indus Civilisation;2015-09-01;2020-08-31;;"Rainfall systems are complex and inherently variable, yet they are of fundamental importance due to their impact on food security. Given that human populations can adapt their behaviour to a wide range of climatic and environmental conditions, it is essential that we understand the degree to which human choices in the past, present and future are resilient and sustainable in the face of variable weather conditions, and when confronted with abrupt events of climate change. TWORAINS will investigate the resilience and sustainability of South Asia’s first complex society, the Indus Civilisation (c.2500-1900 BC), which developed across a range of distinctive environmental contexts where westerly winter rainfall overlapped with the summer rainfall of the Indian Summer Monsoon (ISM). It is now clear that there was an abrupt weakening of the ISM that directly impacted NW India c.2100 BC, and coincided with the start of the decline of Indus cities, but the degree of connection between the two is elusive. Archaeologists have a unique role to play in understanding the ways that societies respond to climate change as they can investigate past instances of success or failure, and the Indus Civilisation provides an ideal laboratory in which to explore how societies can respond to variable and changing rain systems. TWORAINS will combine cutting edge approaches from Archaeology, Earth Sciences and Geography to reconstruct climate, model rain patterns, and explore societal adaptations and responses to change by combining data on settlement distribution, food production and consumption, and water stress. The data will then be integrated and assessed using agent-based modelling. By adopting an integrated interdisciplinary approach, it will be possible to ask “Does climate change really cause collapse?”, elucidate how particular communities perceived weather and landscape changes, hypothesise why they made the decisions they did, and explore the consequences of those decisions.";1999439;1999439;ERC-2014-CoG;/ERC-COG;THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;UK;;;;1;0;0;1;0;0 195205;656044;ClauSeInTEL;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Clausal Selection: Integrating Theoretical with Experimental Linguistics;2015-09-01;2017-08-31;;"The nature of the relationship between a verb and its grammatical dependents is an ancient question in linguistics, tracing back to Aristotelian notions of the subject-predicate relation. A major debate in current theoretical linguistics is how to model this, and the standard view (that the relevant information is stored as part of the grammatical specification of the verb) has been challenged by the development of a new idea: that both the verb and its noun-dependents are embedded inside syntactic hierarchies of fundamentally grammatical elements (socalled “functional categories” encoding notions such as tense, aspect, definiteness and numerosity) and that it is the interaction between the functional category structures that embed the verb and the noun that is responsible for establishing the dependency. This viewpoint has allowed a new and empirically successful understanding of the relationship between a verb and its dependents, capturing how definiteness and grammatical number interact with aspectual categories across different languages. However, this new approach has never been applied to the other major grammatical dependency that verbs set up: clausal complementation. That is, the parallel relation between a verb and its clausal, as opposed to nominal, dependents. This project investigates, using interdisciplinary methods, whether these new theoretical ideas can be applied to this empirical domain, comparing two languages (Greek and English) whose clausal syntax is quite different. The objective is to both test the theoretical model in a new empirical area, leading to new findings about how clausal embedding works syntactically, and to determine how best to develop and extend the model to domains that it was not designed for. The action requires extended training in experimental methods and design (both behavioural and neurolinguistic), statistical analysis, development of systematic theoretical models, as well as interaction with a non-academic partner";183454,8;183454,8;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;QUEEN MARY UNIVERSITY OF LONDON;UK;;;;1;0;0;1;0;0 195632;658614;MoStMusic;CLOSED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Models of Structure in Music;2016-09-01;2018-08-31;;"Music is an art form with a very long history, and continues to engage millions of people today. Music Information Retrieval (MIR), the exciting interdisciplinary science that brings together music and computer science, is a growing field of research with the potential to enrich computer science knowledge while creating real-world applications that everyone can benefit from. While the marriage of art and science is often troublesome, MIR has the benefit that many aspects of music are highly structural and have been subject to formalisation for a long time. Formalisation and computers go hand in hand, and MIR researchers have therefore been developing models of musical structure for many years, and putting them to use in several applications. However, such models, so far, have had limited impact; they're commonly restricted to one specific aspect of music, can be hard to implement computationally, and are often too technical to be used directly by musicologists who are not familiar with programming details. However, models are valuable. Unlike machine learning approaches, model-based MIR provides a real insight about the underlying structure, and can benefit from the input of musicologist experts. Furthermore, a single model can be applied to multiple important MIR tasks. The research goal of this project is thus to give musical models the impact they deserve, advancing the practical embodiment of hierarchical musical structure-in its various forms-in computer science through the development of new, functional Models of Structure in Music (MoStMusic). Specifically, I intend to develop functional models of musical form, melody, and harmony that enable an easy, fast, and flexible way of creating model-enhanced MIR applications. As a showcase of such an application, I will create an online music analyser that automatically computes the structure present in a user-submitted piece, and displays it in an interactive interface that highlights the structural shape of music.";165598,8;165598,8;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;UNIVERSITEIT UTRECHT;NL;;;;1;0;0;1;0;0 195742;659205;Pathologies;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Pathologies of temporality. Abnormal experiences of time in mental disorders;2016-09-01;2017-08-31;;The goal of the proposed research project is to analyze temporal disturbances in mental disorders and, as a result, to create a “map” of pathological experiences of time. The map will be phenomenological in nature, i.e. cutting across existing classifications of mental disorders and avoiding untimely biological explanations. The project is highly interdisciplinary – it is situated at the intersection of phenomenology of temporality, philosophy of history and phenomenology of mental illness. It continues the tradition of philosophical-psychiatric reflections on time in mental disorders that started a century ago and that concerned temporal disturbances in conditions such as: addictions, amnesia, anxiety, dementia, depression, mania and schizophrenia. At the same time it enriches the existing empirical, clinical knowledge with non-medical interpretative schemes. The norm against which particular abnormalities will be assessed is going to be a value-based model of the relationship between past, present and future, and not value-free, physicalist notion of temporality. The major contribution that the project is going to make is bridging the gap between studies in philosophical textual analysis concerning temporality, which are theoretically sophisticated yet lack clinical references, and clinical papers, which will not serve its usual practical, medical function but pragmatically oriented philosophy. As a result, the study will constitute a major step toward answering two highly relevant philosophical-medical questions. First, can pathologies of temporality be interpreted as disorders in themselves, and not as epiphenomena built upon primary mental illnesses, and therefore provide ground for uniting otherwise separated categories of mental disorders? Second, how and to what extent can philosophical notions of time be applied not only to understanding of psychopathological phenomena but also to their treatment?;97727,4;97727,4;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;UK;;;;1;0;0;1;0;0 195526;657937;Hadza communication;CLOSED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Communication Development in Infants: the Case of the Hadza Hunter-Gatherers of Tanzania;2015-11-01;2017-10-31;;"The way children learn to communicate verbally and non-verbally depends to a great extent to the culture in which they are raised. Much is known about the social environment of children living in Western societies, but much less is known about how children are socialized in hunter-gatherer societies. The proposed project aims at gaining insights into the development of communication in hunter-gatherer children. The project’s aims are • to develop a minimally intrusive assessment method that gives access to the learning process by including physiological measures. • to analyze physiological responses to infants’ verbal and non-verbal interactions with their social environment focusing on the Hadza, as a particularly interesting cultural community. • extract patterns in data from diverse sources (audio, video, observation, electrophysiological measures) with automated data mining methods. The approach is interdisciplinary, integrating methods from anthropology and ethology with modern physiological assessment methods, innovative wearable technology and data mining techniques. It is important to know more about the development of communication in Hadza infants as communication in hunter-gatherers has not been comprehensively studied and the Hadza are a community living in conditions that resemble our ancestors’ living conditions. This helps to shed light on the evolution of language in our species. As hunter-gatherer societies are increasingly threatened due to ecological, economic and political changes in their environment, it is crucial to conduct this research as soon as possible. My personal training targets are to apply my previous field work experience to a new and interesting cultural community and relate this to theories about the evolution of language, to fruitfully combine methods from different disciplines and learn how to use data mining techniques in order to analyze large amounts of data from various sources.";177598,8;177598,8;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;STICHTING KATHOLIEKE UNIVERSITEIT BRABANT;NL;;;;1;0;0;1;0;0 195246;656318;MoTOR;CLOSED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Analysis of the “moonlighting” proteins in the mTOR-signalling pathway;2016-02-01;2018-01-31;;The mechanistic target of rapamycin (mTOR) is a highly conserved serine/threonine kinase in eukaryotic organisms. mTOR is the catalytic subunit of two different complexes (mTORC1 and mTORC2), which differ by their subcellular localization and function. The mTORCs integrate the environmental and cellular signal and regulate a broad range of downstream growth events. Impaired regulation of mTOR was often observed in tumors, Alzheimer’s disease, several metabolic disorders, and is known to accelerate aging. Thus, the study of the mTOR pathway is of paramount importance for both fundamental biology and medicine. A tremendous amount of studies have been carried out to elucidate the regulatory role of mTOR in metabolism and diseases. Yet the detailed mechanism of the mTOR regulatory pathway remains to be completed. Recently, using the novel method “mRNA interactome capture”, the host laboratory identified proteins involved in the mTOR-signalling pathway that acts as RNA-binding proteins (RBPs) in yeast, mouse embryonic stem cells (mESC) and HeLa cells. This finding revealed a conserved and previously unrecognized function of the mTOR pathway with RNA being an important component of it. Here I propose a project aiming to unravel the biological function of RNAs and RBPs in the mTOR pathway. In this project, I will use the budding yeast Saccharomyces cerevisiae as a model system, and will identify the novel RNA binding domains (RBDs) of the RBPs. I will further investigate the network of the interacting RBPs and RNAs. This will elucidate the biological impact of the RNA-protein interactions in the mTOR pathway. I will carry out this interdisciplinary study using biochemical and genetic methods, as well as large-scale analysis. The datasets created in this study will open new perspectives on the mTOR regulatory pathway.;171460,8;171460,8;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;EUROPEAN MOLECULAR BIOLOGY LABORATORY;DE;;;;1;0;0;1;0;0 195766;659306;ORRmetIR;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Development and in situ Infrared study of Novel Strained Core-shell Electrocatalysts: Towards an Understanding of the Oxygen Reduction Mechanism;2015-04-01;2017-03-31;;"The oxygen reduction reaction (ORR) is critical in fuel cells (FC), batteries and corrosion. Sluggish kinetics of the ORR remains a key barrier to efficient electricity generation in FC operating on renewable fuels such as hydrogen or alcohols. Poor understanding of the ORR mechanism has hindered development of cost-effective and improved FC catalysts. This project aims to bring about a step change in development and understanding of ORR catalysts by (i) synthesising metal nanoparticles with a strained surface structure, and (ii) developing and implementing new in situ and operando infrared (IR) spectroscopic techniques to understand how strain impacts the ORR mechanism. Novel strained core-shell Pt-based catalysts will be developed, featuring a core of inexpensive metals including Ni, Co or Cu. For the first time, insight into the ORR mechanism for supported electrocatalysts under realistic catalytic turnover will be gained by modifying an approach to combining IR spectroscopy and electrochemistry developed in the Vincent group. The University of Oxford is uniquely suited for this ambitious project: the applicant will be hosted in a strong research culture in catalysis, have access to state-of-the-art research infrastructure and technical expertise in spectroscopy and materials characterisation and industrial collaborations. The fellow will receive broad-ranging training in the synthesis of catalysts and surface characterisation. The host team will benefit from her skills in in situ vibrational spectroscopy, especially spectral interpretation of ORR intermediates. This highly interdisciplinary project combines nanomaterial synthesis, spectroscopy and electrocatalysis, and has strong potential for generation of intellectual property and commercialisation of new catalysts for FC, aiding knowledge transfer between academic and industrial sectors. This will increase Europe’s competitiveness in FC and electrocatalysis, supporting Horizon 2020’s Energy Security goals.";195454,8;195454,8;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;UK;;;;1;0;0;1;0;0 197288;661739;Multi-JOBINSEC;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Micro- and Macro-Level Determinants of Job Insecurity Perceptions: Individual, Organizational and Social Consequences. Multilevel Analysis and Comparisons among Countries;2015-09-01;2017-08-31;;This project aims to increase the understanding of the nature of job insecurity by examining its causes and consequences through a multilevel perspective, considering factors at the individual, organizational and country levels. We intend to provide theoretical models identifying antecedents of job insecurity and potential effects on life quality: the practical goal is to develop instruments for suitable organizational and social policies that could address in a comprehensive way the problem of job insecurity now and in the future. We propose to test micro- and macro-level predictors and consequences of job insecurity combining 3 different data sources: ESS, EUROSTAT, PSYCONES. Perceived threat of job loss has became one of the most prominent job stressors and several studies have shown its detrimental effects on employee’s well-being, health, and job attitudes. However, research in work psychology has focused on the role of individual-level variables, thus neglecting the possibility that job insecurity might also be a contextual stressor. Individual employees may feel their situation as threatened even if there is no apparent objective threat. This fundamental distinction between subjective and objective job insecurity is not acknowledged by economists. Their studies on macro-aggregate data consider only temporary employment and do not reveal how individuals experience job insecurity. The present proposal aims to integrate economic and psychology perspectives examining predictors and outcomes also related to labour market’s macro-economic situation, in addition to individual characteristics and organizational conditions. Taking a cross-cultural perspective we can assess the generalizability of job insecurity in various countries and especially examine how higher-level variables influence lower-level relationships (cross-level analyses in the multilevel perspective). In this way,we can encompass interdisciplinary aspects concerning psychology,economics and sociology;160800;160800;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;KATHOLIEKE UNIVERSITEIT LEUVEN;BE;;;;1;0;0;1;0;0 195326;656787;Ethics and Ageing;CLOSED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Ethics and Ageing;2015-10-01;2017-09-30;;"Population aging will raise formidable ethical challenges for the European Union in the coming decades. Declining fertility rates and increased longevity are gradually increasing the ‘dependency ratio’ – the ratio of persons aged over 65, to persons of working age. In 2010, the EU-wide dependency ratio stood at 26%; by 2050, it will rise to 50% (Eurostat projections). As the balance in numbers shifts from citizens who work to those who are retired, the question of how to sustain the key programmes of the welfare state becomes ever more pressing. How can EU public policymakers best maintain their commitment to social solidarity under conditions of population ageing? This research project proposes a comprehensive analysis of the ethical challenge posed by population aging. It is based on the following guiding observation: while European Union policy-makers (especially in the European Commission) are conscious of the fact that the EU needs an overall strategic approach to this challenge, they do not have at their disposal scholarship that provides an ethical analysis of this challenge at the appropriate level of generality. The project will be based in the Department of Philosophy of Law at Universitat Pompeu Fabra (UPF). It will be supervised by Professor Andrew Williams, one of the world’s leading political philosophers, under the auspices of the UPF research group, the “Philosophy of Law”. Additionally, the project will be developed in dialogue with one of the world’s leading social scientists on the welfare state and population aging, Professor G?sta Esping-Andersen, who runs the “DEMOSOC” research group at UPF. The project will thus have an interdisciplinary character, moving back and forth between ethics and social science, and more specifically, between these two research groups at UPF, with the aim of producing comprehensive and grounded guidance on a key challenge facing the European Union.";170121,6;170121,6;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;UNIVERSIDAD POMPEU FABRA;ES;;;;1;0;0;1;0;0 195365;656967;PYROCHEM;CLOSED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Biopolymers 13C tracking during fast pyrolysis of biomass-A 2-level mechanistic investigation;2015-10-01;2017-09-30;;The Marie Sk³odowska-Curie Actions (MCSA) proposal is the opportunity for Dr. Marion Carrier to reach a new level of understanding of fast pyrolysis mechanisms and improve the process and design of reactors by acquiring the necessary knowledge at a molecular-level and training using fractionation and isotopic characterization techniques, practical experience on micro-reactors and on larger scale laboratory reactors. It is proposed to use an integrated experimental and computational approach to provide molecular-level insights into pyrolysis chemistry by following the fate of 13C labelled lignocellulosic biopolymers, and subsequently to elucidate the main chemical events during the conversion of biomass. Empirical and mechanistic models will be combined to suggest a new kinetic model of fast pyrolysis. The thermal behaviour of individual unlabelled and labelled biopolymer carefully extracted will be investigated under controlled kinetic regime. The delineation and quantification of primary and secondary reactions will be achieved via the development of new devices for the collection of organic volatiles and via the implementation of spectrophotometric and spectrometric methods. For this, a combination of strong interdisciplinary expertise in several fields such as biopolymer chemistry, thermochemistry, aerosols trapping device fabrication, characterization of gas, liquid and solid products using spectrophotometric and spectrometry techniques is required. This multidisciplinary project will facilitate the commercialization of emergent renewable energy technologies such as fast pyrolysis via the optimization of bio-oil yields and quality, which is expected to offer alternative solutions in the co-production of fuels, high-value-added chemicals and energy, the main research activities of European countries members of the International Energy Agency.;183454,8;183454,8;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;ASTON UNIVERSITY;UK;;;;1;0;0;1;0;0 195511;657796;CREST UNDER TENSION;TERMINATED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Mechano-regulation of neural crest cell differentiation.;2015-05-01;;;"Neural crest cells (NCC) are a unique vertebrate-specific population of multipotent cells that contribute to the development and evolution of the vertebrate head. During embryonic development, cranial NCC give rise to a variety of hard and soft tissue cells including osteoblasts, chondrocytes, odontoblasts, glia and neuronal cells. Whilst we understand a great deal about how growth factors and soluble chemicals determine the generation, migration, proliferation, survival and differentiation of the neural crest, nothing is known about how mechano-regulatory factors influence NCC fate. Recent evidence has shown that mesenchymal stem cell fate and cell behaviours are controlled by mechano-regulatory signals via the actinomyosin skeleton, and the co-transcriptional effectors, Yap and Taz. Given that NCC are similarly exposed to different mechanoregulatory influences from stiff and soft matrices and tensions generated by the differential growth and morphogenesis of adjacent epithelial and mesenchymal structures, it is hypothesized that NCC differentiation is also mechano-regulated. This proposal will use in vitro and in vivo approaches to test this hypothesis and determine if NCC fate is governed by mechano-regulatory signals, the differential regulation of the actinomyosin skeleton and Yap/Taz. The proposal will provide novel insight into the mechanisms of embryonic cell differentiation and craniofacial birth defects. Additionally, as neural crest stem cells have been identified in the adult, it will provide an understanding of how these may be manipulated to generate specific cell populations for tissue repair. The proposal will test a novel hypothesis and provide research training in a unique interdisciplinary skill set encompassing biology and engineering at the forefront of research field in addition to transferable skills. The Fellow will be mentored by two internationally recognised supervisors, who are experts in developmental biology and engineering.";183454,8;183454,8;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;KING'S COLLEGE LONDON;UK;;;;1;0;0;1;0;0 195134;655577;LOVe;TERMINATED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Linking Objects to Vectors in distributional semantics: A framework to anchor corpus-based meaning representations to the external world;2015-06-01;2017-05-31;;"Language mediates between concepts in our mind and the things they refer to in the world. Semantic theories are typically biased towards conceptual or referential aspects. My goal is to develop a theory of meaning that takes both aspects into account, and is supported by computational modelling experiments, so that it will also enable computers to match linguistic expressions with entities in the world. This is a highly interdisciplinary proposal that will bring computational linguistics, artificial intelligence, and theoretical linguistics forward. My model is based on distributional semantics, a scalable and flexible approach to computational semantics that, by inducing meaning representations from naturally occurring data with statistical methods, can model large portions of the lexicon and account for nuances in meaning that pose difficulties to traditional semantic theories. Distributional semantics has so far largely eschewed the reference issue, by testing its models on language-internal tasks. The project bridges this language-world gap, and integrates the distributional framework into a referential semantic theory. The project promises to advance our scientific understanding of language, a defining trait of the human species, and to make significant progress towards building computers we can talk to, with the ensuing strong impact on our everyday lives. Even though I am an established researcher in computational semantics and also contributed to semantic theory, I still need to fully develop my own line of research to become a leading, independent researcher in Europe. Carrying out the present proposal at the University of Trento CLIC laboratory will be a fundamental step towards achieving my goal, since CLIC is a world leader in distributional semantics. Conversely, my unique profile, addressing theoretical linguistic questions through computational means, will fill a gap in the lab, widening the scope and outreach of the research conducted at CLIC.";180277,2;180277,2;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;UNIVERSITA DEGLI STUDI DI TRENTO;IT;;;;1;0;0;1;0;0 194466;646659;NANOREACTOR;SIGNED;H2020-EU.1.1.;ERC-CoG-2014;H2020;Multiscale modelling of stimuli-responsive nanoreactors;2015-08-01;2020-07-31;;"The catalysis by metal nanoparticles is one of the fastest growing areas in nanoscience due to our society's exploding need for fuels, drugs, and environmental remediation. However, the optimal control of catalytic activity and selectivity remains one of the grand challenges in the 21st century. Here, I propose to theoretically derive design rules for the optimization of nanoparticle catalysis by means of thermosensitive yolk-shell carrier systems. In the latter, the nanoparticle is stabilized in solution by an encapsulating, thermosensitive hydrogel shell. The physicochemical properties of this polymeric 'nanogate' react to stimuli in the environment and thus permit the reactant transport and the diffusion-controlled part of the catalytic reaction to be switched and tuned, e.g., by the temperature or the pH. The novel hybrid character of these emerging 'nanoreactors' opens up unprecedented ways for the control of nanocatalysis due to new designable degrees of freedom. The complex mechanisms behind stimuli-responsive nanocatalysis call for a concerted, interdisciplinary modelling approach that has converged in my group in the recent years. In particular, it can only be achieved by combining my expertise in multiscale computer simulations of solvated polymers with the statistical and continuum mechanics of soft matter structures and dynamics. The key challenge is to integrate the molecular solvation effects and our growing knowledge of hydrogel mechanics and thermodynamics into advanced reaction-diffusion equations for a quantitative rate prediction. In addition, I envision exciting novel phenomena such as a chemo-mechanical 'self-regulated catalysis' or an amplifying 'resonant catalysis', if hydrogel response and fluctuations couple to the chemical output signal. The expected results and design principles will help our collaborators to synthesize tailor-made, superior nanocatalysts and will advance our understanding of their structure-reactivity relationship.";1987500;1987500;ERC-2014-CoG;/ERC-COG;ALBERT-LUDWIGS-UNIVERSITAET FREIBURG;DE;HELMHOLTZ-ZENTRUM BERLIN FUR MATERIALIEN UND ENERGIE GMBH;DE;;1;0;0;1;0;0 195245;656306;MecaMorphEME;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Four-dimensional physical modeling and numerical simulation of the early mouse embryo morphogenesis.;2015-09-01;2017-08-31;;"The quantitative understanding of the early development of mammalian embryos is essential to the progress of reproductive medicine. Yet, the physical and mechanical principles governing their morphogenesis remain largely unknown. Early mouse embryos self-organize by a succession of cell divisions, deformations and rearrangements, leading ultimately to the specification of two distinct cell lineages, segregated in inside and outside layers. Mechanical forces are therefore as important as biochemical activity in this process and precise 4-dimensional imaging of cells within the embryo reveals intense surface dynamics, regulated by contractile and adhesion proteins. However, our understanding of early embryos development still lacks a precise physical model integrating a dynamic description of the mechanical forces controlling cell shape and cell-cell adhesion. I will design a 4D physical model of the early mouse embryo providing accurate cell dynamics predictions. Cell shapes are primarily controlled by the actomyosin cortex and they will be described using recently developed cortical active shell theories. To represent accurately cell-cell adhesion dynamics, I will consider the crosstalk between cortical and adhesion proteins activities. Importantly, this model will be designed in close collaboration with an experimental group expert in the biophysical characterization of the mouse embryo, to incorporate measured mechanical parameters and molecular regulation mechanisms. Our model will be refined through cycles of theoretical predictions and experimental validations to uncover the principles of early mammalian embryos development and, more specifically, the mechanism of cell internalization at the 8 to 16 cells transition. This interdisciplinary project, at the interface between physical modeling and developmental biology will provide a unique and accurate biophysical framework for understanding the morphogenesis of early mammalian embryos.";171460,8;171460,8;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;EUROPEAN MOLECULAR BIOLOGY LABORATORY;DE;;;;1;0;0;1;0;0 194975;654521;MOSUDO;TERMINATED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Water and Drug Mobility at Silica Surfaces probed with DOSY NMR;2015-04-01;2017-03-31;;Europe’s pharmaceutical industry is faced with the multitude of lead compounds that are discarded during their development phase. One of the hurdles of most promising drugs is that they have difficulties reaching their site of action in the human body. This insufficient bioavailability results from the complex, poorly understood interplay between drug molecules, water and the surfaces of drug delivery materials and cell membranes. To tackle this challenge, a paradigm shift that recognizes water as headline act is proposed. The physical properties of water drastically change when approaching solid surfaces or cell membranes. Nobel Prize winner Albert Szent-Györgyi even described life itself as “water dancing on the tune of solids”. This research proposal aims to gain understanding of water and drug molecule mobility near silica surfaces. Silica materials in recent years popped up as most promising materials for drug delivery. Unravelling the complex interplay between drug, water and silica surfaces will equip pharmaceutical scientists with a generic toolbox to enhance the bioavailability of newly developed drug candidates. MOSUDO research focuses on probing the mobility of water, amino acids with varying hydrophilicity and a peptide drug in contact with silica. Diffusion-Ordered Nuclear Magnetic Resonance spectroscopy (DOSY NMR) is living spectacular developments and revolutionary sensitivity improvement. This project will take advantage of this development of DOSY NMR to investigate the complex molecule-water-surface interplay with new eyes. Fellowship applicant Dr. Randy Mellaerts can rely on a strong interdisciplinary background in surface chemistry and pharmacy. Acquiring in-depth technical expertise in DOSY NMR and its direct application in pharmaceutical industry will complement his current research profile and allow him to embark at the highest scientific level in a for society very important research area.;185076;185076;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FR;;;;1;0;0;1;0;0 195303;656724;InterDemo;TERMINATED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Intercultural Democracies: insights from mining conflicts for environmental justice in plurinational Bolivia and Ecuador.;2015-10-01;;;"Claims from hitherto excluded indigenous groups have led to the rewriting of constitutions in Bolivia and Ecuador to recognize intercultural democracy. At the same time, indigenous environmental justice movements have increased their contestation of hydrocarbon extraction – and recently mining – due to their socio-political and ecological impacts. Analysis of these movements to date has focused on the consequences of conflicts, but less so on their socio-political and ecological drivers. While evidence has demonstrated the role of an increasing social metabolism as a driver of extraction, less attention has been paid to power relations and competing socio-political forces. These deeply influence the possibilities for a democratic control of the extractive sector, a crucial factor for achieving environmental justice and sustainability. This research aims to unpack the power relations that lie beneath the biophysical flows of expanding resource extraction in the intercultural democracies of the Andes. Two mining-related conflicts in Cuenca Poopó (Bolivia) and Intag (Ecuador), where indigenous organizations claim greater environmental justice specifically through self-determination as part of intercultural democracy, will be analyzed applying mixed methodologies: quantitative analysis of biophysical flows and qualitative analysis of interviews and data. This research will potentially show how ecological and metabolic drivers limit indigenous groups’ democratic participation through multi-scale power relations around resource appropriation, thereby improving the understanding of the political dimensions of these conflicts and informing more sustainable policies for extractive sectors. Training at the host institution (ICTA) will facilitate this research by complementing the candidate’s knowledge of political theory with skills in metabolic analysis and the interdisciplinary approach to environmental justice that forms the basis of ICTA’s world-renowned research.";158121,6;158121,6;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;UNIVERSITAT AUTONOMA DE BARCELONA;ES;;;;1;0;0;1;0;0 195352;656891;COUPCAT;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2014-GF;H2020;Coupling dimerisation and metathesis reactions to produce propene from ethanol using heterogeneous catalysts and microreactor systems;2015-04-01;2018-03-31;;"Biomass-derived molecules contain excess oxygen that must be removed to render as fuel or chemicals. Due to feedstock fluctuations, ethanol and ethene are becoming key components to overcome these challenges. Given the current bioethanol (fermentation) and ethene (crackers) excess, and the propene shortage in Europe, alternative routes are required. During the outgoing phase under the supervision of Prof. Iglesia at UC Berkeley (USA), the researcher Dr. Iker Agirrezabal-Telleria will address the fundamental mechanistic aspects of dimerisation and metathesis reactions from ethanol to propene operating at low-temperature and studying the individual parameters using multidisciplinary approaches. This will include spectroscopic (in-situ UV-VIS and FTIR ) and isotopic techniques to elucidate the contribution and role of active metals for dimerisation (Ni), isomerisation (H\) and metathesis (Re, Mo). The optimised catalysts will be tested during the return phase under the supervision of Prof. Arias at the University of the Basque Country (Spain) using engineering approaches. Catalyst slurry and formulations will be prepared to test them on microreactor systems. The microreactors will be coated during a secondment period under the supervision of Prof. Kolb at Fraunhofer ICT-IMM (Germany). This phase aims to achieve process intensification and reduce heat-transfer issues occurring in packed-bed reactors. The comparison between fixed-bed and microreactors will enable to obtain interdisciplinary inputs to produce propene from ethanol. This Fellowship aims to carry out cutting-edge scientific training and transferable skill training such as project management, relevant for the re-integration period and to become an independent research leader in Europe. Moreover, this projects aims to have a positive impact on European society and competitiveness. These actions will involve outreach activities, results dissemination and IPR management.";257191,2;257191,2;H2020-MSCA-IF-2014;/MSCA-IF-GF;UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA;ES;;;;1;0;0;1;0;0 195390;657096;MULTICELL;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Division of labour and the origin of multicellularity;2015-07-01;2017-06-30;;"Understanding the evolution of multicellularity and cellular differentiation/ complexity is one of the greatest challenges in biology. Of particular interest is to determine the evolutionary processes (selective causes) and mechanisms underlying the evolutionary transition from single cells to multicellular organisms. This project will use cyanobacteria as a model system to determine whether cellular differentiation is a cause or consequence of multicellularity. A novel theory will be tested, which predicts that the division of labour/ differentiation among cells drives the transition to a multicellular state. This will be contrasted with the classical view, where cellular specialization originates only at a much later state during the transition. The proposed project will adopt an interdisciplinary approach by combining experimental evolution (WP1) with phylogenomics (WP2). More specifically, populations of unicellular cyanobacteria will be subjected to long-term experimental evolution under two different regimes that favour either the specialization of cells into performing different physiologically incompatible processes, or the formation of non-differentiated aggregates (WP1). By linking the phenotype to the underlying genotype and to gene expression patterns, the critical steps for the transition to multicellularity will be established at the genome level. This evolutionary sequence will be directly compared to the one inferred from the cyanobacterial phylogeny (WP2). Here, whole genomes will be used to reconstruct the gain and loss events for the main ‘multicellular traits’, such as filament formation and cellular differentiation. The findings will not only provide insight into the key events during the transition to multicellularity but will also be the first study that directly relates a transition that was achieved under artificial conditions in the laboratory to one that actually happened more than 3 billion years ago in this phylum.";171460,8;171460,8;H2020-MSCA-IF-2014;/MSCA-IF-EF-RI;CHRISTIAN-ALBRECHTS-UNIVERSITAET ZU KIEL;DE;;;;1;0;0;1;0;0 212220;774567;SOPHIE;SIGNED;H2020-EU.3.2.5.;BG-06-2017;H2020;Seas, Oceans and Public Health in Europe (SOPHIE): a Strategic Research Agenda for Europe and Beyond;2017-12-01;2020-05-31;;"A Growing body of evidence indicates that the marine environment and human health are inextricably linked. These linkages encompass both risks to health and wellbeing, and a range of potential benefits and opportunities. However, much of this early evidence has been established in the US, under the rubric of the integrative meta-discipline of “Oceans and Human Health” (OHH). Far less is known about these issues in other parts of the world, including the European context which faces its own set of unique challenges and opportunities. Building on the early leadership shown by members of the consortium mapping these issues in Europe, the Seas, Oceans and Public Health in Europe (SOPHIE) consortium brings together an international multidisciplinary European team of marine, health, social and economic science experts and practitioners to explore these relationships in the European context. By including a broad range of interdisciplinary partners from both marine and health sectors, SOPHIE can demonstrate reach across disciplines and communities in Europe and internationally. Responding directly to the BG-06-2017 call, SOPHIE’s primary aims are to: a) deliver a clear, evidence-informed Oceans and Human Health Strategic Research Agenda (SRA) within the European context, based on extensive involvement by diverse stakeholders; and b) ensure that the structures needed to develop and implement this SRA are in place and will exist as a legacy beyond the life of the project. These aims will be achieved by: (i) systematic synthesis of the current evidence base; (ii) developing and coordinating a European community of OHH stakeholders; (iii) identification of innovative solutions to sustainably reduce risks and promote benefits; (iv) scenario modelling and horizon scanning; (v) knowledge exchange through bespoke training and skills programmes; and (vi) a global OHH Conference to present SOPHIE’s findings and enhance European leadership and global cooperation in OHH research.";2000000;2000000;H2020-BG-2017-1;/CSA;THE UNIVERSITY OF EXETER;UK;"SEASCAPE BELGIUM;BREAKAWAY TRAVEL;NATIONAL UNIVERSITY OF IRELAND GALWAY;EUROPEAN MARINE BOARD IVZW;RIJKSINSTITUUT VOOR VOLKSGEZONDHEID EN MILIEU;STICHTING DELTARES;ASSOCIACIO SUBMON: DIVULGACIO, ESTUDI I CONSERVACIO DE L'ENTORN NATURAL";"BE;ES;IE;NL";;1;0;0;1;0;0 205322;682741;CAPRI;SIGNED;H2020-EU.1.1.;ERC-CoG-2015;H2020;Children and Adolescents with PaRental mental Illness: Understanding the ‘who’ and ‘how’ of targeting interventions;2016-10-01;2021-09-30;;"At least 10% of mothers and 5% of fathers have a mental illness. Family, educational and social lives of children and adolescents with parental mental illness (CAPRI) are disrupted by deprivation and repeated hospitalisation. This is an urgent political and public health concern. The Child and Adolescent Mental Health in Europe (CAMHEE) report urges us ‘to acknowledge and attend to the needs of children and families with parental mental health... ’ recommending better information on CAPRI risks and resilience so interventions can target those at highest risk. This groundbreaking interdisciplinary programme exploits my unique combination of expertise in epidemiology and neuroscience to deliver on CAMHEE objectives for CAPRI. Previous work focuses on these ‘high risk’ children primarily to examine mental illness heritability. In a crucial departure from this, Work Packages (WP) 1 and 2 exploit my collaborations in Sweden and Australia to create unique linkage across 3 population datasets. This will detail CAPRI numbers and a broad range of life outcomes disentangling effects of social adversity over time. But population epidemiology alone cannot reveal how risk creates effects in individuals. To understand ‘how’ to identify ‘who’ we target for costly interventions, WP 3 links the epidemiology with powerful neuroimaging (near infrared spectroscopy NIRS) to discover which at-risk infants of mothers with severe mental illness show abnormal cognitive development at the level of individual brain. This work capitalises on my role at the University of Manchester, one of the leading academic psychiatry and imaging centres in the UK, to create a new Centre in Bioepidemiology. My future aim is that epidemiological profiling combined with NIRS biomarkers of cognition in individuals will identify which high risk children need what intervention. Future work can then evaluate different interventions and fits seamlessly with my research goal to improve the life outcomes of CAPRI.";1999337,5;1999337,5;ERC-2015-CoG;/ERC-COG;THE UNIVERSITY OF MANCHESTER;UK;KAROLINSKA INSTITUTET;SE;;1;0;0;1;0;0 193520;637738;PoLiChroM;SIGNED;H2020-EU.1.1.;ERC-StG-2014;H2020;Superfluidity and ferromagnetism of unequal mass fermions with two- and three-body resonant interactions;2015-04-01;2020-03-31;;"Superfluidity and magnetism characterize a wealth of interacting fermion systems encompassing solid-state, nuclear and quark matter environments. From the interplay of these phenomena, the two following issues have been raised: Can superfluid pairing bear a mismatch in the two Fermi surfaces? Can a homogeneous fermion system become ferromagnetic via a zero-ranged interparticle repulsion? Despite decades of interdisciplinary investigations, such questions have not gotten undisputed answers so far. Here, I will experimentally address these problems with a new model system composed of ultracold fermionic Chromium and Lithium atoms with resonant interactions. The two species will mimic electrons of different spins, or quarks of different colours, but exhibiting the high degree of control of an atomic quantum simulator. In particular, two features make this system stand far beyond any other available one: the peculiar Chromium-Lithium mass ratio enables a resonant control of three-body elastic interactions on top of the usual two-body ones, together with an extraordinary suppression of atom recombination into paired states in the regime of strong interspecies repulsion. The first property greatly enhances the observability of elusive polarized superfluid regimes, such as the Fulde-Ferrel-Larkin-Ovchinnikov phase, where pairs condense in nonzero momentum states, and the Sarma or “breached pair” phase, where a homogeneous gapless superfluid coexists with unbound particles. The second makes such mixture a prime platform for the quantum simulation of Stoner’s model for itinerant ferromagnetism, whose study has been denied in nowadays experiments, where pairing instability plagues the formation of sizeable magnetic domains. I will use high-resolution imaging of the system and state-of-the-art spectroscopy schemes for disclosing such exotic phases via a thorough investigation of the phase diagrams of Fermi-Fermi mixtures with attractive or repulsive interactions.";1495000;1495000;ERC-2014-STG;/ERC-STG;CONSIGLIO NAZIONALE DELLE RICERCHE;IT;;;;1;0;0;1;0;0 205201;694559;DevelopingTheatre;SIGNED;H2020-EU.1.1.;ERC-ADG-2015;H2020;Developing Theatre: Building Expert Networks for Theatre in Emerging Countries after 1945;2016-10-01;2021-09-30;;"This research project proposes a fundamental re-examination of the historiography of theatre in emerging countries after 1945 . It investigates the institutional factors that led to the emergence of professional theatre in the post-war period throughout the decolonizing world. The particular focus will be on the massive involvement of internationally coordinated ‘development’ and ‘modernization’ programs both East and West. The project will introduce the concepts of epistemic community, expert networks and techno-politics to theatre historical research as a means to historicize theatre within transnational and transcultural paradigms and examine its imbrication in globalization processes. This institutional and transnational approach will enable theatre studies to overcome its still strong national and local focus on plays and productions and connect it to current discourses on transnational history. The main objectives of this project are to: • examine how a global ‘epistemic community’ centred around theatre emerged in the post-war period; • investigate how ‘expert networks’ composed of government bodies, private foundations, transnational corporate philanthropy, local elites and individual artists sought to institutionalize particular forms and practices of professional theatre as an interconnected, transnational phenomenon; • develop a new interdisciplinary approach to theatre historiography by focusing on institutional structures, path dependencies and transnational imbrications rather than on works and authors. The principal investigator will bring to this project two decades of internationally recognized research into intercultural and global theatre. With its combination of institutional historiography and innovative research methods the project will provide a new foundation for current discussions of cultural policy and sustainability in emerging societies.";2150083;2150083;ERC-2015-AdG;/ERC-ADG;LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN;DE;;;;1;0;0;1;0;0 214317;798326;AXO-MATH;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2017;H2020;Imaging and analyzing dynamics of reward-related long-range axons during decision-making in behaving mice;2018-05-01;2020-04-30;;"Decision-making is a crucial brain function which neuronal substrates are largely unknown. Deciphering those mechanisms is critical for the prevention and the treatment of brain diseases as decision-making is maladaptive in many neuropsychiatric disorders (obsessive behaviors, schizophrenia, autism, substance abuse); it would also significantly advance neuroeconomics and therefore positively impact society. AXO-MATH (MATHematical analysis of AXOnal projections) investigates the neuronal mechanisms involved in decision-making in behaving mice using interdisciplinary approaches and state-of-the-art methods. We hypothesize that a final step before the action is taken is implemented in the dorsal PFC as it is an anatomical hub receiving projections from both sensory areas and regions believed to participate in choice valuation, such as the ventral tegmental area and the basolateral nucleus of the amygdala. Using an original combination of advanced microscopy and genetic and viral tools, we will image the activity of those long-range axons in two conditions: while the expert animal is taking a choice, and during the stage of preference learning. Precise measures will allow us to test a model in which projections from the amygdala to the PFC encode choice values and can be dynamically modulated as a function of the context by the ventral tegmental area to switch preference. The characterization accuracy will be unprecedented thanks to the design of new analytical tools - the initial expertise of the applicant. We propose novel mathematical methods tailored to the automatic extraction of complex-shape and micrometer-scale features of synaptic activity in in vivo microscopy images; they lack human input and can handle large volumes of data. By a seamless combination of the host and applicant multidisciplinary expertise we will address the relationship between synaptic network dynamics and functional brain plasticity which is a major challenge in modern neuroscience.";185076;185076;H2020-MSCA-IF-2017;/MSCA-IF-EF-ST;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FR;;;;1;0;0;1;0;0 199596;692419;BLUEandGREEN;SIGNED;H2020-EU.4.b.;H2020-TWINN-2015;H2020;Boosting scientific excellence and innovation capacity in biorefineries based on marine resources;2016-01-01;2019-03-31;;"The exploitation of the ocean unraveled a huge diversity of organisms producing innovative compounds used as pharmaceuticals, nutraceuticals, cosmeceuticals and antifoulings. The aim of BLUEandGREEN is to strength the performance of CIIMAR - Interdisciplinary Centre of Marine and Environmental Research, from the low performing Member State Portugal, in the emergent area of marine biotechnology. This will be done by the establishment of a scientific strategy for stepping up and stimulating scientific excellence and innovation capacity in partnership with four internationally-leading counterparts at the EU level: the University of Helsinki, Finland, the University of Bergen, Norway, GEOMAR, Helmholtz Centre for Ocean Research Kiel, Germany, and Fundación MEDINA, Spain. BLUEandGREEN scientific strategy includes: to review the latest research and innovation advances in the sector, identify and address institutional network gaps and deficiencies; to raise staff´s research profile and excellence by training and mentoring; to increase stakeholder interaction and mobilization to research and innovation partnerships; to guide research to contribute to economic growth; to deliver a framework for strengthening a long-term research and innovation environment in marine biotechnology. The network enhancement will enforce cluster dynamics in close interaction with industrial partners to contribute to regional, national and EU Blue Growth strategies, especially to marine biotechnology industry. The implementation of brokerage with stakeholders and market-oriented projects will dismantle trade barriers, increase the ways of communication among partners and promote knowledge enhancements and its conversion in business. Being Portugal, especially North Portugal, a peripheral region, this will contribute to the change its economic landscape, giving new opportunities for development and job creation and reinforcing the role of marine biotechnology in the economic development of Europe.";996687,5;996687,5;H2020-TWINN-2015;/CSA;CIIMAR - Centro Interdisciplinar de Investigaç?o Marinha e Ambiental;PT;"HELSINGIN YLIOPISTO;FUNDACION CENTRO DE EXCELENCIA EN INVESTIGACION DE MEDICAMENTOS INNOVADORES EN ANDALUCIA;HELMHOLTZ ZENTRUM FUR OZEANFORSCHUNG KIEL;UNIVERSITETET I BERGEN";"FI;ES;DE;NO";;1;0;0;1;0;0 222450;844129;CYBERCULT;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Strategic Cultures of Cyber Warfare;2019-06-03;2021-06-02;;CYBERCULT is a project that examines why and how western states are developing Offensive Cyber Capabilities (OCC): human, technical and virtual tools to disrupt, destroy and exploit computer systems. CYBERCULT has three core objectives. First, it will establish a Strategic Culture-based theoretical concept that explains the development and use of OCC by western powers. This concept will move beyond rationalist and materialist explanations of OCC processes and consider the influence of Strategic Culture on OCC adoption, including the socio-political, historical, and perceptual/ideational factors involved. This will be achieved through a theory-building phase involving an Interdisciplinary Workshop on OCC, a literature review on Strategic Culture and new technologies, and sustained interaction with leading Strategic Culture academics. Second, CYBERCULT will produce a data set on perceptions of OCC in eight countries that are connected to the western alliance system: the US, Israel, France, Germany, the UK, Estonia, Japan and New Zealand. The data set will be based on an analysis of surveys sent out to cyber policymakers and practitioners in the eight countries. Third, CYBERCULT will produce an in-depth comparative analysis of OCC adoption in three of the world's leading cyber powers: the US, Israel, and France. This will be based on primary and secondary sources and twenty interviews with scholars, government officials, and cyber industry representatives in each of the three countries. CYBERCULT will have sustained links to policymaking and industry and will help to inform fast-moving cyber security processes in the EU and NATO, including the EU Cyber Security Strategy and NATO Cyber Defence Policy. CYBERCULT will be hosted by Recherche et Etudes en Politique Internationale (REPI), Université Libre de Bruxelles (Belgium). The key deliverables are a journal article, a book, three policy briefs, and two working papers.;166320;166320;H2020-MSCA-IF-2018;/MSCA-IF-EF-ST;UNIVERSITE LIBRE DE BRUXELLES;BE;;;;1;0;0;1;0;0 222079;838688;HeBo;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2018;H2020;Healthcare at the Borders: Managing Camps and Informal Settlements for Refugees and Migrants;2020-09-01;2022-08-31;;The management of migrants, refugees and asylum-seekers is one the most complex issues the EU is facing: HeBo aims to tackle it from the perspective of healthcare implementation in migrant camps and informal settlements situated within the European territory. In such spaces, both healthcare actions and their omission assume specific meanings, including the form of border management technology. HeBo thus focuses in particular on the following main research objects: A) the management of migrants in contemporary Europe through the lens of the right to healthcare, B) the relationship between the implementation of the right to healthcare and European border policies, and C) the implementation of the right to health as a translation of the politics of life and the differentiated judgement of lives underlying the current migration management in the EU. While the implementation of healthcare in humanitarian contexts has been largely studied in extra-European countries, it remains understudied for camps and, in particular, informal settlements within the European space. Through ethnographic inquiry on governmental and non-governmental healthcare units, HeBo focuses on three crucial sites across the EU: the islands of Lampedusa (Italy) and Lesbos (Greece), and the area of Calais (France). HeBo will build on the expertise that Dr. Alunni developed in his previous work on healthcare within Roma camps in Italy. Professor Didier Fassin, who will supervise HeBo, is a leading scholar in the field of humanitarianism and on issues of power and health inequalities, and will therefore support Dr. Alunni with his experience. Due to the excellent quality of its infrastructure, scholarly research and staff, the IRIS (Interdisciplinary Research Institute in Social Sciences) at the EHESS (École des Hautes Études en Sciences Sociales, Paris) will constitute the most appropriate academic environment for Dr. Alunni to become a leading social science scholar in the European Research Area.;184707,84;184707,84;H2020-MSCA-IF-2018;/MSCA-IF-EF-ST;ECOLE DES HAUTES ETUDES EN SCIENCES SOCIALES;FR;;;;1;0;0;1;0;0 211844;757833;FORMICA;SIGNED;H2020-EU.1.1.;ERC-2017-STG;H2020;Microclimatic buffering of plant responses to macroclimate warming in temperate forests;2018-02-01;2023-01-31;;"Recent global warming is acting across ecosystems and threatening biodiversity. Yet, due to slow responses, many biological communities are lagging behind warming of the macroclimate (the climate of a large geographic region). The buffering of microclimates near the ground measured in localized areas, arising from terrain features such as vegetation and topography, can explain why many species are lagging behind macroclimate warming. However, almost all studies ignore the effects of microclimatic buffering and key uncertainties still exist about this mechanism. Microclimates are particularly evident in forests, where understorey habitats are buffered by overstorey trees. In temperate forests, the understorey contains the vast majority of plant diversity and plays an essential role in driving ecosystem processes. The overall goal of FORMICA (FORest MICroclimate Assessment) is to quantify and understand the role of microclimatic buffering in modulating forest understorey plant responses to macroclimate warming. We will perform the best assessment to date of the effects of microclimates on plants by applying microtemperature loggers, experimental heating, fluorescent tubes and a large-scale transplant experiment in temperate forests across Europe. For the first time, plant data from the individual to ecosystem level will be related to microclimate along wide temperature gradients and forest management regimes. The empirical results will then be integrated in cutting-edge demographic distribution models to forecast plant diversity in temperate forests as macroclimate warms. FORMICA will provide the first integrative study on microclimatic buffering of macroclimate warming in forests. Interdisciplinary concepts and methods will be applied, including from climatology, forestry and ecology. FORMICA will reshape our current understanding of the impacts of climate change on forests and help land managers and policy makers to develop urgently needed adaptation strategies.";1498469;1498469;ERC-2017-STG;/ERC-STG;UNIVERSITEIT GENT;BE;;;;1;0;0;1;0;0 208648;748671;LEEP;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Longitudinal employer–employee perspectives on the role of human capital investments for retirement transitions;2017-10-01;2019-09-30;;"European and national ageing policies give high priority to increasing retirement age and employability of older people, but no effective solution exists. The project aims to provide practical recommendations based on evidence on the role of human capital investments (at individual and company level) for retirement transitions. This is still an understudied area in ageing research. It is also neglected by policy-makers who miss the fact that employees must be willing and able to work longer, and employers must be willing and able to provide adequate opportunities for extended employment. The project offers an innovative and comprehensive approach to integrate individual and company perspectives theoretically and empirically in a system-level context. It compares two countries that differ greatly across many aspects relevant to retirement decisions, this is Poland and the Netherlands. Empirical evidence is based on longitudinal (panel) data of individuals and employers (supplemented by cross-sectional data). The research adopts a lifecourse approach, considering employment situation and retirement decisions of individuals as a part of life-trajectory. The results will be intensively disseminated among scientist, experts, and policy-makers. They will be also communicated to older people, employers, training and development organisations. The researcher will be based in the 'Work & Retirement' group in NIDI (Netherlands Interdisciplinary Demographic Institute, part of KNAW) – a leading international institute for population studies, particularly for research on employers’ attitudes and behaviours towards ageing workforce. Professor K?ne Henkens, a renowned expert in research on ageing labour markets and retirement, will be the supervisor. Training and two-way knowledge transfer will focus in particular on skills in longitudinal statistics and writing, and on knowhow of project management.";177598,8;177598,8;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW;NL;;;;1;0;0;1;0;0 199924;690901;NANO-SUPREMI;SIGNED;H2020-EU.1.3.3.;MSCA-RISE-2015;H2020;“Tracking nano-bioprocesses using Super-Resolution Microscopy Techniques”;2016-03-01;2020-02-29;;"Long-range research and innovation goal: The long-range goal of Nano-Supremi is to develop case studies to enable the advanced super-resolution microscopy to investigate nanoscale synthetic and biological structures and to probe nanoscale dynamic processes. Long-range biomedical research and technology goal: The implementation of Nano-Supremi will allow for tracking nanometer-scale bioprocesses such as (i) nanomedicines cellular uptake and trafficking and (ii) single-molecule dynamic processes of DNA-protein, (iii) protein-membrane interactions. Key Research Goals: The objective of Nano-Supremi is to turn the following creative research ideas into advanced microscopy technologies and services. This will ultimately results in the evaluation of in vitro protein and DNA activity and therapeutic efficacy of nanomedicines plugging the gap between innovative research and its exploitation in clinical setting. Scientific impact: We identified a few innovative case studies to explore the potentiality of super resolution microscopy techniques in solving nanoscale bio-structures and dynamic processes. Impact on early-stage researchers: Nano-Supremi involves key participation of junior researchers with outstanding record of achievements in education and research, providing strong support for the development of their careers. Intersectoral dimension: A synergistic approach in using advanced technologies developed by microscope manufacturers to answer fundamental and applied questions on bioprocesses will be pursued. Interdisciplinary dimension: A complementary research program, ranging from nanophotonics, materials science, to molecular biology and bio-analytical chemistry, will drive the implementation of research tasks towards the full achievement of the objectives. International dimension: Funding of this program will enable long-term, transformative research collaborations between groups settled in European Countries and in four non-EU Countries (AU, US, Brazil, Cu)";873000;724500;H2020-MSCA-RISE-2015;/MSCA-RISE;UNIVERSITA DEGLI STUDI DI ROMA TOR VERGATA;IT;"FAKULTNI NEMOCNICE U SV. ANNY V BRNE;FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA";"CZ;IT";;1;0;0;1;0;0 205569;721615;PBNv2;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2016;H2020;Next generation Pass-By Noise approaches for new powertrain vehicles;2017-05-01;2021-04-30;;"With transportation noise being the second most deadly environmental pollutant in Europe, engineering for future mobility must be inspired by ecology, economy and health to enable green and silent vehicles. Legislations define maximum noise emission limits that have to be complied with during standardized pass-by noise test procedures. Given novel, often electrified, vehicle powertrain concepts, new pass-by noise evaluation approaches are required. The proposed PBNv2 project (Next generation Pass-By Noise approaches for new powertrain vehicles) brings together early stage researchers and experienced specialists from key players in academia and industry across Europe covering different scientific disciplines and industrial stakeholders form a broad range of backgrounds to optimally tackle the challenges ahead. The Fellows will be trained in innovative PhD topics as well as receiving specific theoretical and practical education in the field of pass-by noise engineering, tackling as well the pass-by noise aspects of the ‘source’, the ‘transfer path’ and the ‘receiver’. PBNv2 is formed by 10 beneficiaries combining leading education institutes, top research institutions and leading companies as well as 7 partner organisations established in European automotive R&D, to assist in the dissemination and public engagement or PBNv2 results, and in providing dedicated training to enhance the entrepreneurial mind set of the ESRs. The Fellows will profit from top scientific research guidance in combination with highly relevant industrial supervision. Together these participants address the triple-I dimension of research training, being International, Interdisciplinary and Intersectoral. Furthermore, the industry will gain from the specific training of the young researchers.";3584644,56;3584644,56;H2020-MSCA-ITN-2016;/MSCA-ITN-ETN;KATHOLIEKE UNIVERSITEIT LEUVEN;BE;"GOODYEAR SA;AIT AUSTRIAN INSTITUTE OF TECHNOLOGY GMBH;ROBERT BOSCH GMBH;TOYOTA MOTOR EUROPE NV;INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE LYON;IDIADA AUTOMOTIVE TECHNOLOGY SA;Kompetenzzentrum - Das Virtuelle Fahrzeug, Forschungsgesellschaft mbH;SIEMENS INDUSTRY SOFTWARE NV;UNIVERSITY OF SOUTHAMPTON";"LU;AT;DE;BE;FR;ES;UK";;1;0;0;1;0;0 212981;777926;NanoSurf;SIGNED;H2020-EU.1.3.3.;MSCA-RISE-2017;H2020;Nanostructural surface development for dental implant manufacturing;2018-01-01;2021-12-31;;"The project NanoSurf is targeted to strengthen international and intersectoral collaboration in dental implant research, sharing new ideas and knowledge transfer from research to market and vice versa. We will investigate nanostructured metal oxide coatings, 3D scaffolds, obtained by electrospinning deposition of organic nanofibers and lazer patterning of the implant surface using biotechnology, cell engineering and nanotechnology. Interdisciplinary project research and innovation goals are targeted to develop a new class of dental implants with advanced mechanical properties and improved surfaces, treated with nanotechnological methods which will demonstrate high biocompatibility, antibacterial properties and integration with a patient’s bone. The developed devices will simplify dental surgery and avoid bacterial inflammatory complications after the implant surgery. This can provide better dental services and improve health of EU society. The project partners will provide research and training activities in the fields of fabrication and characterization of Zirconium-Titanium (ZrTi) alloy-based dental implants, sol-gel deposition of metal oxides, biopolymers and organic/inorganic nanolaminates, laser patterning, electrospinning, structural characterization, cell engineering, modeling analysis and commercialisation of scientific achievements from research results to final product. Research and management training will be provided to experienced and early stage researchers to strengthen their personal skills, improve their track record and expertise via new scientific papers and conference presentations and strengthen a development of EU research human resources. Long lasting collaboration between partners, based on co-supervising students and preparation of novel collaborative project proposals is foreseen. Dissemination of project results will make an impact on development of EU research potential in the fields of bio-, nanotechnology and applied science.";1008000;1008000;H2020-MSCA-RISE-2017;/MSCA-RISE;LATVIJAS UNIVERSITATE;LV;"NANOPHARMA AS;THE UNIVERSITY OF SHEFFIELD;EESTI MATERJALITEHNOLOOGIATE ARENDUSKESKUSE OÜ;SUMY STATE UNIVERSITY;UNIVERSITA DEGLI STUDI DI MODENA E REGGIO EMILIA;OSTEOPLANT RESEARCH AND DEVELOPMENT SPOLKA Z OGRANICZONA ODPOWIEDZIALNOSCIA";"CZ;UK;EE;UA;IT;PL";;1;0;0;1;0;0 193285;634415;PoC-ID;SIGNED;H2020-EU.3.1.3.;PHC-10-2014;H2020;Platform for ultra-sensitive Point-of-Care diagnostics for Infectious Diseases;2015-05-01;2018-11-30;;The aim of the PoC-ID project is to develop new micro- and nanoelectronic-based sensing and integration concepts for advanced miniaturised in vitro diagnostic devices. The project addresses the increasing demand for rapid and ultra-sensitive point-of-care diagnostics to reduce healthcare costs and increase the quality of life with a focus on infectious diseases, one of the world’s leading causes of morbidity and death. Interdisciplinary collaboration using the technology and expertise of the consortium members will be applied to develop and test a breakthrough PoC prototype for the diagnosis of respiratory syncytial virus infections and host responses in the paediatric context. PoC-ID will enable new types of point-of-care diagnostics for virtually any type of complex liquid sample. Applications are disease diagnosis, monitoring of therapeutic responses, clinical research of pathogen-host interaction and personalised medicine. The platform technology can easily be adapted to a variety of diagnostic or biosensing purposes, such as in health/environmental monitoring or food quality testing. PoC-ID will combine the detection of both pathogens and host responses leading to more accurate diagnosis as compared to the current standard which is focused on detection of pathogens only. This novel approach will support prevention and control of pathogen spread and enable faster and more personalised patient treatment. Improved performance in terms of robustness, sensitivity and selectivity will be reached by a combination of innovative nanomembrane technology, molecular engineered capture molecules and two novel sensing concepts. Further advances will be realised in terms of usability and speed of data-analysis arising from the integration of sensors, read-out electronics and microfluidics into one user friendly point-of-care (PoC) platform. Costs of the new disposable sensors will be ultra-low at high volumes, thanks to designing into microelectronics production flows.;5963133,25;5963132,75;H2020-PHC-2014-two-stage;/RIA;TECHNISCHE UNIVERSITAET BERLIN;DE;"APTARION BIOTECH AG;STICHTING KATHOLIEKE UNIVERSITEIT;MICROPATHOLOGY LIMITED;FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.;SERVIZO GALEGO DE SAUDE;FRIEDRICH-SCHILLER-UNIVERSITAT JENA;MERCENE LABS AB;enablingMNT GMBH;CNM TECHNOLOGIES GMBH;SIGNALGENERIX LIMITED;VAN HEEREN ARIE HENDRIK;NOXXON PHARMA AG;MEMSOP CONSULTING";"DE;NL;UK;ES;SE;CY;RO";;1;0;0;1;0;0 193525;637764;Highland Connections;SIGNED;H2020-EU.1.1.;ERC-StG-2014;H2020;Remoteness and Connectivity: Highland Asia in the World;2015-05-01;2020-04-30;;"Asian highlands from the Afghan Pamir to Kashmir, Tibet and Northeast India are of great geopolitical concern. Remote, yet thoroughly connected to the outside world, they figure in public debate alternately as sanctuaries for transnational insurgents, as trafficking routes in the global drug and wildlife trade, and as realms of authentic tribal culture. Though making headlines around the globe as independent cases, we lack a conceptual understanding of their entanglements, role and position in a globally connected world. The aim of this project is to lay the conceptual groundwork for a new apprehension of the positionality of remote areas around the globe. It rests on the hypothesis that remoteness and connectivity are not two independent features but constitute each other in particular ways. My objective is to explore the nexus of remoteness and connectivity – a fundamental dynamic that has never been studied from a comparative, transnational perspective. Highland Asia, the chosen study area spanning the mountain regions between Pamir and Eastern Himalaya, transcends the boundaries of nation-states and area studies. It offers a unique vantage point to reveal a bigger picture. The project is timely. 25 years after the end of the Cold War, Highland Asia experiences a rapid increase in transnational exchange. Old trade routes closed for generations are being re-opened and the quest for natural resources and new markets attracts capital and new actors to the highlands. The hotspots of tension at the edge of Asia’s rising powers are becoming junctures of exchange. The project studies this ongoing but little understood transformation in real time. The project will be carried out by an international team of four researchers at LMU Munich. Interdisciplinary in outlook but grounded in anthropology, 52 months of fieldwork will be conducted in 4 transnational settings in Highland Asia. Results will be published in 2 edited collections, 20 papers, and individual monographs.";1499875;1499875;ERC-2014-STG;/ERC-STG;LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN;DE;;;;1;0;0;1;0;0 221381;823897;ATLANTIC;SIGNED;H2020-EU.1.3.3.;MSCA-RISE-2018;H2020;Advanced theoretical network for modeling light matter interactIon;2019-03-01;2023-02-28;;"The ATLANTIC project is aiming at developing a network of advanced theoretical modeling of laser-matter interaction that will foster the development of novel theories by bridging the mathematical descriptions within a consortium of scientific groups who have pioneered these formalisms. These physical models address in details the timescales from the attosecond to the microsecond and the spatial scales from the nanometer to the millimeter, providing accurate but partial predictions of experimental data in a disjoint manner. Connecting the respective formalisms of these communities will enable to address phenomena that remained unexplained so far and to achieve beyond state of art capabilities. First activity will be directly interfacing the simulation results provided by participants using mathematical parametrizations generated from first-principle concepts to the large spatial scale models, enabling to predict the consequences of laser-triggered quantum effects within an efficient simplified formalism. The secondment periods will be used to develop hybrid theories made possible by training research staffs and novel generations to mutually understand and contribute to the development of each others theoretical descriptions. Interdisciplinarity is at the core of this project as it will be bridging several fields of science: ultrafast phenomena, nonlinear optics, condensed matter physics, quantum chemistry, materials engineering, and laser-materials processing. Within the action, novel formalisms will be developed and emerging applications such as harmonic generation, THz wave generation, laser nanostructuring, materials functionalization, complex materials engineering, compound materials science might be further elucidated (described), and young specialists will be trained.";929200;874000;H2020-MSCA-RISE-2018;/MSCA-RISE;NEW BULGARIAN UNIVERSITY;BG;"IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE;FORSCHUNGSVERBUND BERLIN EV;FYZIKALNI USTAV AV CR V.V.I;THE QUEEN'S UNIVERSITY OF BELFAST;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS";"UK;DE;CZ;FR";;1;0;0;1;0;0 217806;819006;Sci4all;SIGNED;H2020-EU.1.3.5.;MSCA-NIGHT-2018;H2020;Science is for all of us;2018-05-01;2019-12-31;;Citizen science is an efficient way to democratise science, bring the public and science closer together and enhance both public knowledge as well as understanding of science. The key objective of the Sci4all project is to involve the citizen science movement in a frame of several pre-event activities such as trainings, challenges and conferences as well as in a broad spectrum of innovative event activities at the actual European Researchers’ Night. It will incorporate formats such as Science Slams and Science Cafes, more than 34 scientific booths and 16 workshops as well as social activities to bring the public and science closer together, but also to encourage young people to pursue a career in the STEM domains. Interdisciplinarity plays a significant role in this project and the presented innovations and activities integrate more than 25 domains aiming to increase general public awareness of the diversity of scientific research. An important part of Sci4all is also the dedication to the legacy inherited from past generations in order to encourage more people to discover and engage with diverse cultural heritage topics. In this context, Sci4all fits well into the European Year of Cultural Heritage 2018. Researchers from almost all significant research institutions in and around Vienna committed to be part of the Sci4all activities. Moreover. Support for the event promotion was stated by the major public stakeholders, funding agencies, initiatives and therefore according authorities. The Sci4all project integrates 5 partners with different competences, backgrounds and public outreach therefore being able to implement successful European Researchers’ Nights in Austria in 2018 and 2019.;149132,5;149132,5;H2020-MSCA-NIGHT-2018;/CSA;PRACTICAL ROBOTICS INSTITUTE AUSTRIA (PRIA) ZUR FORDERUNG DES WISSENSCHAFTLICH-TECHNISCHEM NACHWUCHSES UBER ROBOTIK IN OSTERREICH;AT;"SCIENCE COMMUNICATIONS SCHUTZ & PARTNER GMBH;KINDERBURO UNIVERSITAT WIEN GMBH;UNIVERSITAET FUER BODENKULTUR WIEN;FH-CAMPUS WIEN - VEREIN ZUR FORDERUNG DES FACHHOCHSCHUL-, ENTWICKLUNGS- UND FORSCHUNGSZENTRUMS IM SUDEN WIENS";AT;;1;0;0;1;0;0 209134;721815;IMforFUTURE;SIGNED;H2020-EU.1.3.1.;MSCA-ITN-2016;H2020;Innovative training in methods for future data;2017-04-01;2021-03-31;;"IMforFUTURE is an innovative multidisciplinary and intersectoral research training programme which addresses current shortcomings in omics research. We aim to open the new research horizon in integration of genetics, glycomics, and epigenomics datasets into systems biology by developing innovative methods for high throughput omics and for integrative analysis of omics data. We focus on ageing, which is the biggest single risk factor for many diseases. By application of our novel methods to emerging datasets representing inflammation and immunology, IMforFUTURE will contribute to understanding of the underlying biological processes involved in diseases and ageing. To be successful in future multidisciplinary environments in Academia or Industry, ESRs need to be able to act as bridge between several diverse disciplines. Our ESRs need to overview all steps from data production via data analysis to data interpretation. In our consortium 7 academic and 4 industrial partners - experimental and theoretical - participate in research and training via teaching, offering secondments and hosting ESRs. We offer courses in high throughput methodology, genomics and statistics. Secondments will be to partners with complementary disciplines and intersectoral. Emphasis will be data management, data stewardship, entrepreneurship, and complementary skills. Interdisciplinary collaborations among ESRs will be stimulated by working on the same studies, in which new data will be generated, integrated with other datasets, analyzed with novel methods and interpreted. At the end of the project the ESRs will present and discuss their research in an integrated workshop. Our ESRs will be ready and equipped for new-generation multidisciplinary researchers. They will significantly contribute to omics research in relationship to human disease and health and knowledge translation. A conference to disseminate our work to researchers in Academia and Industry, and to stakeholders will be organized.";2864761,2;2864761,2;H2020-MSCA-ITN-2016;/MSCA-ITN-ETN;UNIVERSITY OF LEEDS;UK;"ACADEMISCH ZIEKENHUIS LEIDEN;FACULTY OF SCIENCE UNIVERSITY OF ZAGREB;GENOS DOO ZA VJESTACENJE I ANALIZU;GLYXERA GMBH;UNIVERSITAIR MEDISCH CENTRUM UTRECHT;ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA;THE UNIVERSITY OF EDINBURGH;KING'S COLLEGE LONDON";"NL;HR;DE;IT;UK";;1;0;0;1;0;0 216317;801075;NICI;SIGNED;H2020-EU.1.2.1.;FETOPEN-01-2016-2017;H2020;Non-Invasive Chemistry Imaging in the whole human body;2018-06-01;2021-05-31;;"The NICI project’s ambition is to lay the foundations of a new area of research: the study of human biology using non-invasive chemistry imaging. For this, NICI aims to unite two areas of research: metabolomics and magnetic resonance imaging (MRI). Metabolomics studies body functions through the measurement of metabolites; MRI, is able to provide 3D images of the body. By advancing MRI so that it can detect metabolic biomarkers and by discovering powerful new MRI-visible biomarkers, a non-invasive technology can be developed for dynamically mapping biochemical processes in the whole human body. Vision: This new non-invasive technology for imaging biochemical processes in the human body will open a new and effective window for understanding human biology, diseases and their treatment. Breakthroughs: I. Methodology for the discovery of discriminative biomarkers and II. Technological platform for full body biochemical imaging. Novelty: Enabling a paradigm shift from morphologic imaging to biochemical understanding. Foundational: Establishing the basis for a new research area, the study of human biochemistry using non-invasive biochemical imaging. High-risk: i) The exact mechanisms of diseases are largely unknown and ii) Measuring specific metabolites is challenging. Interdisciplinary: Bringing together physicists, biologists, chemists and clinicians. The NICI project will develop a new methodology for the in vitro discovery of discriminant biomarkers using co-cultured 3D organoids as models for human organs. In addition, the project will develop a measurement platform, integrated with 7T MRI scanners and associated data acquisition approaches to adapt these MRI scanners into 3D biochemical imaging systems. NICI will validate the dynamic 3D chemical imaging approach and its predictive and prognostic value by researching a stratification strategy for patients with liver metastasis of gastrointestinal cancer. (This is one out of many possible applications.)";3146973,75;3146973,75;H2020-FETOPEN-1-2016-2017;/RIA;UNIVERSITAIR MEDISCH CENTRUM UTRECHT;NL;"THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;IMAGO 7 FONDAZIONE DI RICERCA ONLUS;SIEMENS PLC;PHILIPS MEDICAL SYSTEMS NEDERLAND BV;Academisch Medisch Centrum bij de Universiteit van Amsterdam;MR COILS BV;NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU;GENERAL ELECTRIC DEUTSCHLAND HOLDING GMBH";"UK;IT;NL;NO;DE";;1;0;0;1;0;0 213008;778157;CanBioSe;SIGNED;H2020-EU.1.3.3.;MSCA-RISE-2017;H2020;Novel 1D photonic metal oxide nanostructures for early stage cancer detection;2018-01-01;2021-12-31;;"The project CanBioSe targeted to strengthen international and intersectoral collaboration, sharing new ideas and knowledge transfer from research to market and vice versa in the field of nanostructured metal oxide optical biosensors for cancer cells detection. Interdisciplinary project research and innovation goals are targeted to develop a new portable tool for early stage cancer detection which can solve on of important health challenges in EU society. One dimensional (1D) polimer nanofibers will be deposited by electrospinning technique. Photonic nanomaterials, based on metal oxide based nanostructures (ZnO, ZnO/Al2O3 nanolaminates, Au/ZnO and ZnO/Au) will coat the 1D nanofibers. Metal oxides and Au nanoparticles will be deposited with Atomic Layer Deposition (ALD) and electrophoresis, respectively. Bioselective layer will be formed by immobilization of specific antibodies on the biosensor surface. Photoluminescence and optical spectroscopy will be used for recording of the biosensor signal. Biosensor testing will be performed on cancer cells (human chronic lymphocyte leukemia (CLL) leucosis and acute lymphoblastic leucosis). The biosensor will be integrated with microfluidic system in order to minimize dimensions and simplify the use of the detection system. The project partners will provide research and training activities in the fields of nanotechnology, surface functionalization, bioengineering, microfluidics and biosensor testing, market analysis and commercialization. Provided research and management training to experienced researchers and early stage researchers will strengthen their personal skills and CVs via new scientific papers and conference theses and strengthen a development of EU research human resources. Long lasting collaboration between partners, based on co-supervising students and preparation of novel collaborative project proposals is foreseen. Dissemination of the project results to scientific society and wide auditories is foreseen.";1282500;1282500;H2020-MSCA-RISE-2017;/MSCA-RISE;LATVIJAS UNIVERSITATE;LV;"NANOPHARMA AS;UNIWERSYTET IM. ADAMA MICKIEWICZA W POZNANIU;ECOLE NATIONALE SUPERIEURE DE CHIMIE DE MONTPELLIER;EESTI MATERJALITEHNOLOOGIATE ARENDUSKESKUSE OÜ;VILNIAUS UNIVERSITETAS;FONDAZIONE BRUNO KESSLER;BIOSENSOR SRL";"CZ;PL;FR;EE;LT;IT";;1;0;0;1;0;0 200693;677355;Hidden Galleries;SIGNED;H2020-EU.1.1.;ERC-StG-2015;H2020;Creative Agency and Religious Minorities: ‘hidden galleries’ in the secret police archives in 20th Century Central and Eastern Europe;2016-09-01;2020-08-31;;"This project concerns the creative agency of religious minorities in the transformation of Central and Eastern Europe societies in the 20th century. It constitutes the first comparative research on the secret police archives in the region from the perspective of the history and anthropology of religion and offers a radical perspectival shift on the value and uses of the secret police archives away from questions of justice and truth to questions of creative agency and cultural patrimony. Interdisciplinary in nature it combines archival, anthropological and cultural studies approaches to provide a re-examination and re-contextualization of the holdings of secret police archives in three states; Romania, Moldova and Hungary. The secret police archives, in addition to containing millions of files on individuals monitored by the state, also constitute a hidden repository of confiscated religious art and publications of religious minorities that were persecuted in the 20th century under fascism and communism. The investigation of these materials will be complemented by ethnographic research and the impact of the research will be extended through a public exhibition of previously hidden materials. The project has three principal stages: 1) copy/retrieve and catalogue examples of this creative material from the archives; 2) engage in ethnographic research with the communities that produced this material in order to explore the meaning and power of these artistic creations at the time of their production and in the context of post-socialism; 3) curate and stage a touring exhibition that re-presents the narratives and experiences of religious groups through their own artistic creations in order to conduct research in real time on questions of religious pluralism and intolerance in contemporary society. Through these three steps, this project will shed fresh light on the role that minority religious groups played in challenging the hegemonic order and in extending pluralism.";990087;990087;ERC-2015-STG;/ERC-STG;UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK;IE;;;;1;0;0;1;0;0 218696;824326;DIAMOND;SIGNED;H2020-EU.3.4.;MG-4-3-2018;H2020;Revealing fair and actionable knowledge from data to support women’s inclusion in transport systems;2018-11-01;2021-10-31;;"Current transport systems do not sufficiently take into account physical and social characteristics of women in the design of products and services, and in fostering women’s employability in the industry. Technologies such as data mining and analytics, together with the use of elicitation techniques to gather and analyse information from different stakeholders, allow the generation of actionable knowledge for addressing gender-specific needs for transport decision-making, planning tools and methods. DIAMOND will exploit such technological advances and innovations, to (i) analyse real-world scenarios where these open issues exist, and (ii) take concrete action, to create a fair and inclusive transport system. DIAMOND’s main goal is to turn data into actionable knowledge with notions of fairness, in order to progress towards an inclusive and efficient transport system. This objective will be achieved by the development of a methodology based on the collection and analysis of disaggregated data, including new sources, analytics and management techniques. Thus this allows to identify, design and evaluate specific measures for fulfilling the needs and expectations of women as users of different transport modes and as jobholders in the sector. The knowledge gathered in the data analysis will then be fed into a toolbox that will provide recommendations on how to achieve fair inclusiveness for women in each of the identified use-cases. Interdisciplinary analysis combining methods from social sciences and computer science will contribute to fairness of the model and its results (i.e. condition of being free from bias or injustice). To proof actionability, this project will make concrete advances in four real-world scenarios (use-cases) where inclusiveness is currently a central issue: 1.- railways and public multimodal transport, 2.- Vehicle Dynamics control towards autonomous driving, 3.- vehicle sharing and 4.- corporate social responsibility and employment.";2628408,75;2628406;H2020-MG-2018-SingleStage-INEA;/RIA;FUNDACIO EURECAT;ES;"Systematica S.r.l.;INSTITIUID TEICNEOLAIOCHTA BHAILE ATHA CLIATH;SYNDICAT MIXTE AUTOLIB ET VELIB MÉTROPOLE;Univerzitet u Beogradu - Saobracajni fakultet;MIASTO STOLECZNE WARSZAWA;HEKSAGON MUHENDISLIK VE TASARIM AS;THE UNIVERSITY OF STIRLING;Ferrocarrils de la Generalitat de Catalunya;RINA SERVICES SPA;EDINBURGH NAPIER UNIVERSITY;GENRE ET VILLE;WAVE WOMEN AND VEHICLES IN EUROPE;AITEC ASESORES INTERNACIONALES SRL";"IT;IE;FR;RS;PL;TR;UK;ES";;1;0;0;1;0;0 193216;633335;REN-ATHENS;CLOSED;H2020-EU.1.3.5.;MSCA-NIGHT-2014;H2020;Researcher's Night: meeting science and your next door scientist;2014-05-01;2015-10-31;;"A diverse team of experts in scientific research and science communication from leading Research Institutes and Educational Organizations located in the Athens Metropolitan area is formed to organize the Researcher's Night activities for the years 2014 and 2015. By adopting the concept “Science invites People”, we propose a large scale REN, in 2014, at NCSR Demokritos, the largest Science Research campus in Attica, and a similar event in 2015, at IME a multiplex where science meets entertainment and exploration, organized by the National Observatory of Athens . Based on past experience, we plan activities for an expected attendance of several thousand visitors. Our proposal involves activities from several scientific domains exemplifying in many cases the benefits of Interdisciplinarity. The activities will include the organization of pre-events, as part of the awareness campaign, as well as parallel events at three regions throughout Greece including Rodos, Corinth and Pylos, where par?icipating Institutions have satellite installations, so as to maximize impact and reach. Researcher's Night 2015 events will be linked with another major Researcher's Night event planned to take place in Rome, through the support of the local establishment of the European Space Agency (ESA). The purpose of the project is to convey to the general public the ideas that Research is a necessary ingredient for progress, the Researchers are an integral part of the community and their profession is both fun, challenging, interesting and worth pursuing. The presentation of the work of the scientists to the Greek public will showcase the need of scientific and technological breakthroughs leading to inventions and opportunities that benefit society in many ways. .";160000;160000;H2020-MSCA-NIGHT-2014;/CSA;"""NATIONAL CENTER FOR SCIENTIFIC RESEARCH """"DEMOKRITOS""""""";EL;"EPISTIMI EPIKOINONIA;IDRIMA MEIZONOS ELLINISMOU;HELLENIC CENTRE FOR MARINE RESEARCH;ATHINA-EREVNITIKO KENTRO KAINOTOMIAS STIS TECHNOLOGIES TIS PLIROFORIAS, TON EPIKOINONION KAI TIS GNOSIS;NATIONAL OBSERVATORY OF ATHENS;ETHNIKO IDRYMA EREVNON";EL;;1;0;0;1;0;0 217793;818873;RENA II;SIGNED;H2020-EU.1.3.5.;MSCA-NIGHT-2018;H2020;REsearchers' Nights organized by Athens area Research Institutions to convey the science benefits to the public and motivate young people to science careers;2018-06-01;2020-01-31;;'A diverse team of experts in scientific research and science communication from leading Research Institutes and Educational Organizations, located in the Athens Metropolitan area and with satellite installations and collaborators all over Greece, is formed to organize the Researcher's Night activities for the years 2018 and 2019. By adopting the concept “Science invites People”, we propose a large scale ReN, in 2018, at NCSR-Demokritos, the largest Science Research campus in Attica and Greece, and a similar event in 2019 at 'Hellenic Cosmos' the Cultural Centre of the Foundation of the Hellenic World, an ultra-modern Cultural Centre and Museum that stands out for its innovative programs, organized by the National Observatory of Athens. Based on past experience, we plan activities for an expected attendance of many thousand visitors. Our proposal involves activities from several scientific domains exemplifying in many cases the benefits of Interdisciplinarity. The activities will include the organization of pre-events, as part of the awareness campaign, as well as parallel events in three regions across Greece including Iraklion Crete, Rethymnon Crete, Corinth, Patras, Kalamata and Xanthi, where participating Institutions have satellite installations, so as to maximize impact and reach. The purpose of the project is to convey to the general public the key ideas that Research is a necessary ingredient for progress, the Researchers are an integral part of the community and their profession is both fun, challenging, interesting and worth pursuing. The presentation of the work of the scientists to the Greek public will showcase the importance of scientific and technological breakthroughs leading to inventions and opportunities which benefit society in many ways. The special activities addressed to kids will motivate young people to choose science careers when they grow up.';185000;185000;H2020-MSCA-NIGHT-2018;/CSA;"""NATIONAL CENTER FOR SCIENTIFIC RESEARCH """"DEMOKRITOS""""""";EL;"EPISTIMI EPIKOINONIA;IDRIMA MEIZONOS ELLINISMOU;HELLENIC CENTRE FOR MARINE RESEARCH;ATHINA-EREVNITIKO KENTRO KAINOTOMIAS STIS TECHNOLOGIES TIS PLIROFORIAS, TON EPIKOINONION KAI TIS GNOSIS;NATIONAL OBSERVATORY OF ATHENS;ETHNIKO IDRYMA EREVNON";EL;;1;0;0;1;0;0 195529;657956;IASS;CLOSED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Immigrant Activity-Space Segregation: Spatio-Temporal Patterns of Assimilation and Separation in Barcelona;2016-01-01;2017-12-31;;This project will deepen society’s understanding of immigration while enabling a young, experienced researcher to acquire new skills by collaborating with a well-established European research group with a long record of high quality academic output. The project will help illuminate the lives of immigrants in Barcelona, focusing on their use of space and time as a way to understand the process of assimilation and barriers to social and economic inclusion. Drawing on the expertise of UPF’s Interdisciplinary Research Group on Immigration (GRITIM-UPF), the researcher (John Palmer) will interview and observe a panel of immigrants over time to learn about their routines and about the places and people with which they come into contact as they go about their daily activities. The researcher will use newly-developed mobile phone geolocation methods to quantify systematic differences in the spatio-temporal distributions of immigrants and natives, while using traditional qualitative approaches to analyse the social significance of these segregation patterns.;170121,6;170121,6;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;UNIVERSIDAD POMPEU FABRA;ES;;;;1;0;0;1;0;0 195008;654861;DAM-NET;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Dam-nations? A study on dams, nation-building and transboundary water relations through case-studies from Ethiopia and Tajikistan;2015-09-01;2017-08-31;;"The aim of DAM-NET is to enable the Future Fellow (FF) to carry out a state-of the art research project, investigating how ruling elites can use the symbolic value of a large hydraulic infrastructure to construct and disseminate their particular idea of the nation and legitimize their hold on power. The study will expand on the largely unexplored link between water and social power, bringing new insights into the analysis of transboundary water relations and on the role that discourse and nationalism play in water politics. Throughout a varied set of activities, the project will allow transfer of knowledge and the training of the FF, thus improving his employability and career perspectives. Interdisciplinary in nature, DAM-NET will draw upon insights from International Relations (IR), nationalism studies and political geography to create a framework for the analysis of the politics of mega-dams. Specifically, two case studies – the Grand Ethiopian Renaissance Dam (GERD) in Ethiopia and the Rogun Dam (RD) in Tajikistan – will serve as a platform to analyse the discursive constructions surrounding mega-dams, and to map and unpack stakeholder and elite networks associated with the water sector in both countries. Besides their scholarly relevance, the research findings will provide important policy insights for a better understanding of the new boom in global dam building, and for the explanation of seemingly irreparable regional conflicts triggered by the construction of extremely costly megaprojects.";183454,8;183454,8;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;THE UNIVERSITY OF MANCHESTER;UK;;;;1;0;0;1;0;0 204349;722973;RENA;CLOSED;H2020-EU.1.3.5.;MSCA-NIGHT-2016;H2020;REsearchers' Nights organized by Athens area Research Institutions to convey the science benefits to the public and motivate young people to science careers;2016-05-01;2017-11-30;;"'A diverse team of experts in scientific research and science communication from leading Research Institutes and Educational Organizations, located in the Athens Metropolitan area, is formed to organize the Researcher's Night activities for the years 2016 and 2017. By adopting the concept “Science invites People”, we propose a large scale REN, in 2016, at NCSR 'Demokritos', the largest Science Research campus in Greece, and a similar event in 2017 at at the Foundation of the Hellenic World, a multiplex where science meets entertainment and exploration, organized by the National Observatory of Athens. Based on past experience, we plan activities for an expected attendance of several thousand visitors. Our proposal involves activities from several scientific domains exemplifying in many cases the benefits of Interdisciplinarity. The activities will include the organization of pre-events, as part of the awareness campaign, as well as parallel events at three regions across Greece including Rhodes, Corinth and Pylos, where participating Institutions have satellite installations, so as to maximize impact and reach. The purpose of the project is to convey to the general public the key ideas that Research is a necessary ingredient for progress, the Researchers are an integral part of the community and their profession is both fun, challenging, interesting and worth pursuing. The presentation of the work of the scientists to the Greek public will showcase the need of scientific and technological breakthroughs leading to inventions and opportunities that benefit society in many ways.'";160000;160000;H2020-MSCA-NIGHT-2016;/CSA;"""NATIONAL CENTER FOR SCIENTIFIC RESEARCH """"DEMOKRITOS""""""";EL;"EPISTIMI EPIKOINONIA;IDRIMA MEIZONOS ELLINISMOU;HELLENIC CENTRE FOR MARINE RESEARCH;ATHINA-EREVNITIKO KENTRO KAINOTOMIAS STIS TECHNOLOGIES TIS PLIROFORIAS, TON EPIKOINONION KAI TIS GNOSIS;NATIONAL OBSERVATORY OF ATHENS;ETHNIKO IDRYMA EREVNON";EL;;1;0;0;1;0;0 210325;750985;MCIATTP;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Molecular to Continuum Investigation of Anisotropic Thermal Transport in Polymers;2017-10-16;2019-10-15;;"In 2014, EU PLASTICS INDUSTRY accounted for 1.4MM jobs and contributed to high living standards of the EU citizens by enabling new and more affordable technologies. Most of the PROCESSING of POLYMERIC MATERIALS occurs under NON-ISOTHERMAL flow conditions. As a result, the COST/ENERGY REQUIRED to manufacture, recycle and dispose polymers is STRONGLY AFFECTED by the thermo-physical properties linkage to state variables such as temperature and stress. Experiments show that flowing polymers exhibit ANISOTROPIC THERMAL CONDUCTIVITY (ATC) (i.e. direction dependent). This phenomenon has been previously NEGLECTED in both the simulation of INDUSTRIALLY relevant flows and the development of a molecularly-based THEORY for thermal transport in polymers. This research targets THIS GAP IN KNOWLEDGE by: 1) EXTENDING molecular-based modelling techniques to include ATC; 2) TRANSFERRING the physical insights to macroscopic network models (MNM) by averaging the important physical processes; 3) VERIFYING the MNM predictions by comparison to experimental data; 4) IMPLEMENTING a robust MNM for ATC in finite element methods (FEM) to simulate prototype flows. This study will COMBINE the ER EXPERIENCE investigating THERMO-PHYSICAL properties of polymers with the expertise of the HI supervisor in the development MNMs and their APPLICATION to FEM. In addition, a SECONDMENT at an expert group in molecular simulation will provide the KNOWLEDGE needed to CONNECT the MICROSTRUCTURE to the MNM. This INTERDISCIPLINARY project will BENEFIT INDUSTRY through the OPTIMIZATION of FABRICATION processes and the assessment of the mechanical and thermal PERFORMANCE OF PLASTICS during use. At a more fundamental level, understanding how micro-structure couples with the macroscopic properties will allow us to TUNE POLYMERS to become BETTER THERMAL CONDUCTORS or INSULATORS. The materials derived from these outcomes will directly IMPACT SOCIETY through more ADVANCED AND AFFORDABLE devices and products.";170121,6;170121,6;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;UNIVERSIDAD DE BURGOS;ES;;;;1;0;0;1;0;0 201065;702650;TOFNITW;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2015-EF;H2020;Transformation of Family Norms in a Transnational World: How LGBT Migrants can Affect Change through Social Remittances;2017-02-01;2019-01-31;;The present study examines transformations of family norms through cross-border exposure to different family models. It focuses on the LGBT migrants from selected Central and Eastern European (CEE) countries with a constitutional same-sex marriage ban, but who now live in same-sex families in Belgium, one of the first countries to legalize same-sex marriage and adoption. This case study will explore how intercultural contact can improve reception of an institutional innovation such as same-sex family. This project is based on in-depth interviews with two groups sustaining ties across borders: (1) the CEE gays and lesbians in same-sex marriage or raising children with a same-sex partner in Belgium, and (2) their non-migrant family members, friends and neighbours in home communities. Migrant transnationalism scholars have established that migrants can effect change in their home communities not only by sending remittances, but also by transferring ideas and practices (social remittances). But empirical investigations of this phenomenon are still scarce, and typically focus on democratic ideas and practices. In a novel approach, the present study will analyse social remittances by examining cross-cultural effects of the institutional innovation of same-sex family, and it will further position its findings into the wider framework of social change analysis. In light of the European Parliament's recent decision to include LGBT and same-sex families' rights into the new EU gender equality strategy, the study's conclusions will also inform relevant policy strategies. By developing this study at the Interdisciplinary Research Centre on Families and Sexualities at the UCL, the project will benefit from Centre's multidisciplinary perspective and expertise in transnational migrations, family norms and sexuality, to which the project will add a new perspective on the LGBT migrants from CEE, thus deepening Centre's focus on LGBT studies and widening their regional expertise.;172800;172800;H2020-MSCA-IF-2015;/MSCA-IF-EF-ST;UNIVERSITE CATHOLIQUE DE LOUVAIN;BE;;;;1;0;0;1;0;0 210600;754380;ResearchLeaders2025;SIGNED;H2020-EU.1.3.4.;MSCA-COFUND-2016;H2020;Research Leaders 2025 - A Fellowship Programme developing the Next Generation of Agri-Food Research Leaders;2018-08-01;2023-07-31;;"The overriding objective of this programme is to foster the next generation of agri-food research leaders. Inspired by the Marie Sk³odowska-Curie Actions (MSCA) Global Fellowships, it focuses on researcher-driven mobility. The programme offers applicants the opportunity to conduct their research in an academic or non-academic organisation of their choice worldwide (outside of Ireland) for 18 months, followed by a return phase to Teagasc (Ireland) for 18 months. The applicant will freely choose the research topic, the outgoing host (and supervisor) and the supervisor for the return phase. In addition, if the outgoing phase is with an academic host, they may choose to incorporate a secondment for up to six months to a non-academic collaborator of their choice. Interdisciplinary projects will be encouraged and facilitated. The programme will have a total value of €5.2 million (€2.1 million from EC). It will run for 60 months and will have two funding calls; each funding 10 fellowships (total 20 fellowships). Each fellowship will last 36 months. There will be a strong focus on the career development of the researchers, with all fellows undertaking an accredited management course, having a dedicated career mentor (separate to their scientific supervisors) and attending an annual retreat with presentations from established research leaders in industry, academia and civil society organisations. The need to address the “leaky pipeline” whereby many promising female researchers do not achieve senior positions is a strong focus of the programme. An International Expert Advisory Board will review all documentation for the programme to ensure that there is no unintended bias against, or discouragement of, female applicants. Remote review cohorts and the final review panel will be gender balanced. A dedicated section of the website will highlight positive reasons for female researchers to apply for the fellowship.";4248000;2124000;H2020-MSCA-COFUND-2016;/MSCA-COFUND-FP;TEAGASC - AGRICULTURE AND FOOD DEVELOPMENT AUTHORITY;IE;;;;1;0;0;1;0;0 209609;749814;Urban Informality;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2016;H2020;Capital Accumulation Through Informal Urbanization in India;2017-09-04;2019-09-03;;Unauthorized development, informal real estate & housing markets and informal settlements, referred to collectively here as 'informal urbanization' (IU), remain durable, and likely expanding, in much of the global South. IU hampers the implementation of any urban development plan or policy that require land and which require adequate information about land use and above and below ground infrastructure. While much is known about how capital is accumulated and regulated in sectors of the formal economy, much less is known about how this works in the informal economy and very little is known about how this works in IU sectors. This is due to the assumption, influenced by de Soto's work, that the lack of formal property rights leads to 'dead capital', i.e., capital that cannot accumulate. This wisdom must be challenged for if IU is a significant domain of accumulation, then policies and politics by planners and lawmakers for sustainable & inclusive urban development range from inadequacy to lack of fitness for purpose. This Fellowship integrates David Harvey's accumulation theory with Barbara Harriss-White's social structure of accumulation approach to the informal economy to establish a new strand of research. Fieldwork will occur in two municipalities in India where IU is widespread. The aims are: (1) synthesize the theory & evidence of accumulation via IU and its consequences for urban governance and inclusive development more generally (2) qualitatively study & record the phenomena in six cases (3) apply cross-case analysis and (4) disseminate findings via journal articles, policy briefs, city reports, roundtables with respondents, curriculum input & guest lectures. Based at the Contemporary South Asian Studies Program in the School of Interdisciplinary Area Studies at Oxford, with fieldwork in India, the project strengthens my: research networks, research & project management skills and contributes to fields of urban studies, geography & development studies.;195454,8;195454,8;H2020-MSCA-IF-2016;/MSCA-IF-EF-ST;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;UK;;;;1;0;0;1;0;0 209851;754446;Athenea3I;SIGNED;H2020-EU.1.3.4.;MSCA-COFUND-2016;H2020;Attracting and Encouraging Triple I Talent Mobility;2017-10-01;2022-09-30;;"Athenea3I is an innovative regional wake-up call focused on attracting highly talented researchers to Granada (Andalusia region, Spain) in order to benefit their research career with International, Interdisciplinary and Intersectorial opportunities. This innovative fellowship programme offers the experienced researchers an outstanding opportunity to develop new skills and competences, enriched with a personalized and pioneering career mentoring plan. It also includes research periods at some of the most distinguished outstanding institutions around the world, and optional secondments in regional, national and international companies. The high-talented human capital hired by the University of Granada, as beneficiary institution, will perform as active “magnets” in relation not only to academy, but to industry and business, establishing bridges for transfer of knowledge, exploitation of the results, and future research collaborations. Athenea3I commitment pivots on the applicability of the research outputs by making Science for Society: reinforcing not only the innovation aspect but also the open data access and the public engagement. It has on target the social challenges of Andalucia2020, shooting up their results to palliate some socio-economic problems of the region and, consequently, to get towards the Europe2020 targets.";4248000;2124000;H2020-MSCA-COFUND-2016;/MSCA-COFUND-FP;UNIVERSIDAD DE GRANADA;ES;;;;1;0;0;1;0;0 195589;658332;WFL;SIGNED;H2020-EU.1.3.2.;MSCA-IF-2014-EF;H2020;Morphology beyond inflection. Building a wordformation based dictionary for Latin;2015-11-01;2017-10-31;;"The proposed project aims at the compilation of a derivational morphological dictionary of the Latin language, which connects lexical elements on the basis of wordformation rules, through the use of computational linguistic methods. The final resource will be both a standalone tool accessible through its own website, and interconnected with the Index Thomisticus Treebank (IT-TB), a syntactically annotated corpus of texts of Thomas Aquinas, currently based at the Centro Interdisciplinare di Ricerche per la Computerizzazione dei Segni dell’Espressione (CIRCSE), at the Universita’ Cattolica del Sacro Cuore in Milan. The integration with the IT-TB will be operated through the embedding of the dictionary data within the morphological layer of annotation of the treebank, using TEI (Text Encoding Initiative) P5 conformant XML encoding which will ensure easy sharing and linking of the data across a variety of potentially related projects, and will make sure, through the use of an internationally recognised standard for the encoding of textual data, such data will be re-usable and expandable in the future.";180277,2;180277,2;H2020-MSCA-IF-2014;/MSCA-IF-EF-ST;UNIVERSITA CATTOLICA DEL SACRO CUORE;IT;;;;1;0;0;1;0;0 197131;665822;QUANTEXBIO;TERMINATED;H2020-EU.1.3.4.;MSCA-COFUND-2014-DP;H2020;Quantitative and Experimental Biology;2015-11-01;2020-10-31;;Biology is in an era in where the formerly dominant mode of experimentation is complemented by sophisticated data analysis, theoretical modelling and visualization strategies. Perhaps the most critical challenge is to train scientists, able to craft questions that are amenable to interrogation of big data and vice versa. Centred at the University of Dundee’s College of Life Sciences (CLS), the QUANTEXBIO programme will offer a unique menu of doctoral training projects and mobility to a cohort of high-quality ESRs. This inter-disciplinary programme will provide research training at the highest levels of excellence with supervision by leaders in the fields of Life Sciences, Bio-physics, Mathematics, Computing and Computational Biology. Research projects for each 4 year training programme will be chosen by each ESR, with a transparent evaluation and fellowship awarding process based on excellence. The inter-disciplinary research described in these projects is designed to provide great career opportunities for researchers with expertise in quantitative bioinformatics, physics and mathematics based modelling techniques as well as those with strong backgrounds in human and plant life-sciences. Unbounded by traditional research silos, subjects range from cancer and developmental biology to crop growth all unified under a modelling and quantitative sciences approach. Whilst tackling challenging problems that cut across distinct disciplines, interactions and networking opportunities with leading scientists from across the EU will be assured through a flexible schedule of secondment opportunities to leading industrial and academic organisations. A programme of symposia and workshops involving the cohort of researchers, CLS researchers and partner organisations will maximize impact to stakeholders and society at large. The strategic goals for this programme are synergistic with the CLS €30Mn Centre for Translational and Interdisciplinary Research which opened in 2014.;3348480;1674240;H2020-MSCA-COFUND-2014;/MSCA-COFUND-DP;UNIVERSITY OF DUNDEE;UK;;;;1;0;0;1;0;0 ;;;;;;;;;;;;;;;;;;;;;;;;;; ;;;;;;;;;;;;;;;;;;;;;;;;;; ;;;;;;;;;;;;;;;;;;;;;;;;;; ;;;;;;;;;;;;;;;;;;;;;;;;;; ;;;;;;;;;;;;;;;;;;;;;;;;;; ;;;;;;;;;;;;;;;;;;;;;;;;;; ;;;;;;;;;;;;;;;;;;;;;;;;;; ;;;;;;;;;;;;;;;;;;;;;;;;;; ;;;;;;;;;;;;;;;;;;;;;;;;;; ;;;;;;;;;;;;;;;;;;;;;;;;;; ;;;;;;;;;;;;;;;;;;;;;;;;;; ;;;;;;;;;;;;;;;;;;;;;;;;;; ;;;;;;;;;;;;;;;;;;;;;;;;;; ;;;;;;;;;;;;;;;;;;;;;;;;;; ;;;;;;;;;;;;;;;;;;;;;;;;;; ;;;;;;;;;;;;;;;;;;;;;;;;;; ;;;;;;;;;;;;;;;;;;;;;;;;;; ;;;;;;;;;;;;;;;;;;;;;;;;;; ;;;;;;;;;;;;;;;;;;;;;;;;;; ;;;;;;;;;;;;;;;;;;;;;;;;;; ;;;;;;;;;;;;;;;;;;;;;;;;;; ;;;;;;;;;;;;;;;;;;;;;;;;;; ;;;;;;;;;;;;;;;;;;;;;;;;;; ;;;;;;;;;;;;;;;;;;;;;;;;;; ;;;;;;;;;;;;;;;;;;;;;;;;;; ;;;;;;;;;;;;;;;;;;;;;;;;;; ;;;;;;;;;;;;;;;;;;;;;;;;;; ;;;;;;;;;;;;;;;;;;;;;;;;;; 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