rcn;id;acronym;status;programme;topics;frameworkProgramme;title;startDate;endDate;projectUrl;objective;totalCost;ecMaxContribution;call;fundingScheme;coordinator;coordinatorCountry;participants;participantCountries;subjects;IDR;TDR;Title_Interdisciplinar*;Objective_interdisciplinar*;Title_transdisciplinar*;Obj_transdisiplinar* 90191;229597;EIPOD;ONG;FP7-PEOPLE;PEOPLE-2007-2-3.COFUND;FP7;European Molecular Biology Laboratory Interdisciplinary Postdocs;2009-12-01;2014-11-30;;The European Molecular Biology Laboratory (EMBL) has a strong tradition in promoting interdisciplinary basic research in molecular biology. With 93 laboratories in eight Research Units at five facilities in four European countries, working on topics ranging from structural to organismal biology and from computational and biophysics to chemical biology, the EMBL is one of the top research institutions in the world. The idea of the new EMBL Interdisciplinary POstDoc (EIPOD) initiative is to make use of this unique international, multidisciplinary research environment for setting up a postdoc fellowship programme devoted to broadening the interdisciplinary education and expertise of Experienced Researchers (ERs). Once a year, we invite young researchers to propose interdisciplinary projects of their choice to EMBL faculty of their preference. Candidates are asked to contact at least two group leaders, preferably of different Research Units, to discuss and shape projects that bring together separate scientific disciplines or transfer techniques to new usage. Scientific excellence of applicants and interdisciplinarity of the proposed work are evaluated by an independent selection committee composed of EMBL Heads of Units and other external internationally renowned scientists in a two-step procedure, involving a pre-selection followed by an interview meeting. Besides high-level interdisciplinary research training, EIPODs receive additional vocational training, special career development support and can join our new double mentorship scheme. An active alumni network facilitates reintegration into national research environments. Fellowships last three years. The COFUND contribution will be used to increase the number of fellowships from 12 to 20 and to introduce additional social benefits for the EIPODs in accordance with the European Charter for Reseachers. We aim to maintain these improved standards beyond the COFUND period.;9155700;3662280;FP7-PEOPLE-2007-2-3-COFUND;/MC-COFUND;EUROPEAN MOLECULAR BIOLOGY LABORATORY;DE;;;"/REG;/SCI";1;0;1;6;0;0 104163;291772;EIPOD2;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-COFUND;FP7;EMBL Interdisciplinary Postdocs 2;2012-07-01;2017-06-30;;'The European Molecular Biology Laboratory (EMBL) has a strong tradition in promoting interdisciplinary basic research in molecular biology. With 83 laboratories in eight Research Units at five facilities in four European countries, working on topics ranging from structural to organismal biology and from computational and biophysics to chemical biology, the EMBL is one of the top research institutions in the world. The EMBL Interdisciplinary PostDoc (EIPOD) fellowship programme makes use of this unique international, multidisciplinary research environment to broaden the interdisciplinary education and expertise of Experienced Researchers (ERs). Once a year, EMBL invites young researchers to propose interdisciplinary projects of their choice to EMBL faculty of their preference. Candidates are asked to contact at least two group leaders, preferably from different research units, to discuss and shape projects that bring together separate scientific disciplines or transfer techniques to new usage. Scientific excellence of applicants and interdisciplinarity of the proposed work are evaluated by an independent selection committee composed of EMBL Heads of Unit and other external internationally renowned scientists in a two-step procedure, involving a pre-selection followed by an interview meeting. Besides high-level interdisciplinary research training, EIPODs receive additional vocational training, special career development support and can join the EMBL double mentorship scheme. An active alumni network facilitates reintegration into national research environments. Fellowships last three years. The COFUND contribution will be used to maintain our current number of fellowships of 20 per year and to introduce additional social benefits for the EIPODs in accordance with the European Charter for Researchers. We aim to maintain these improved standards beyond the COFUND period.';11865561,01;4746224,4;FP7-PEOPLE-2011-COFUND;/MC-COFUND;EUROPEAN MOLECULAR BIOLOGY LABORATORY;DE;;;/SCI;1;0;1;6;0;0 107145;334315;NeutAndalus;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-CIG;FP7;NeutAndalus: boosting interdisciplinary neutron science in Spain and Europe;2014-01-01;2017-12-31;;"Neutrons are not only essential components of matter, their interactions with nuclei are crucial in many of the important processes occurring in nature. Among others, neutron capture reactions in stars are responsible for the creation of all elements beyond iron, fission reactions drive nuclear power reactors, neutron absorption reactions are the base of promising cancer therapy techniques, scattering of neutrons is a powerful tool for the study of materials, and material damage from neutrons is crucial for the use of electronic in avionics. The present project aims at boosting neutron science in Spain and Europe and leading the creation of two new competitive infrastructures for the interdisciplinary use of neutrons. The project will consist on: 1. Perform at least two start-of-the-art experiments in the most powerful neutron beam facilities of Europe: “Reactor g-ray heating studies at EXOGAM@ILL: prompt g-ray emission from fission in U and Pu isotopes” and “Study of the 79Se s(n,g) for the determination of the main and weak s-process contributions to the nucleosynthesis in stars for the A=80 mass region”. 2. Design, build and exploit a D-T neutron beam facility using the existing accelerators of University of Seville and the associated National Centre of Accelerators CNA. The use of the new neutron beam line will be interdisciplinary: nuclear data for fission and fusion, irradiation of electronic components for avionics, and medical physics. 3. Create an interdisciplinary research team for the design, construction and long-term exploitation of a versatile neutron beam facility at the new LINAC Research Facility LRF, which is already being constructed in Spain with EU Structural Funds. The community supporting this project includes several research groups with interests in a variety of fields: basic nuclear physics, innovative nuclear technology, nuclear astrophysics, medical application of neutrons, and irradiation of materials and electronics for avionics.";100000;100000;FP7-PEOPLE-2012-CIG;/MC-CIG;UNIVERSIDAD DE SEVILLA;ES;;;/LIF;1;0;1;3;0;0 95611;249598;MUSDIG;ONG;FP7-IDEAS-ERC;ERC-AG-SH5;FP7;Music, Digitization, Mediation: Towards Interdisciplinary Music Studies;2010-10-01;2015-12-31;;"Music is rapidly being transformed by digital technologies; it is in the vanguard of the changes to contemporary cultures and cultural economies afforded by digitization, and is widely seen as a test case of digitization’s effects. Yet the academic music disciplines have not responded with research on these fundamental developments. This project, by combining two innovative interdisciplinary components, aims systematically to advance the state of contemporary music research, while contributing to social and media theory. It will be the first research programme to analyse comprehensively the range of interrelated transformations in music and musical experience wrought by digital technologies. The first element of the project is a comparative programme of ethnographic studies examining transformations in creative, performance and improvisation practices, the nature of music as a cultural object, new aesthetic forms, altered modes of musical consumption and circulation, and changing industry and institutional structures. Given the ease of transnational distribution of digitized musics, research will also follow certain genres as they circulate among diasporic groups. These and related issues will be studied in five countries, each intrinsically significant as well as yielding instructive comparisons between them: the UK, Cuba, Kenya, India and Turkey. The emphasis in each ethnography will be on analyzing the embedded nature of digital musical practices in local cultural, social, economic and political conditions. Second, on the basis of this programme, the project aims to advance contemporary music research by developing an interdisciplinary theory and methodology which progresses beyond the current state of the field. Music research has been divided between disciplines such as musicology and music analysis which address the musical object and centre on art musics, and sociological and anthropological approaches which privilege music’s social, institutional and discursive forms and focus primarily on popular and vernacular musics. The present project bridges these divisions by expounding an innovative theory and methodology focused on music’s mediation, one that integrates recent elements of social, anthropological and media theory. Moreover it addresses music’s digital transformations across the spectrum of contemporary musics: art, popular and vernacular, commercial and non-commercial. Given that music’s core properties – mediation, performance, improvisation, affect, complex materialities – are also core concerns of contemporary social theory, the research will in turn contribute to ‘musicalising’ social theory. The project aims to have far-reaching impacts, creating a field of comparative studies of digital music cultures while reconfiguring the interdisciplinary foundations of music research.";1708075;1708075;ERC-2009-AdG;/ERC-AG;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;UK;ROYAL HOLLOWAY AND BEDFORD NEW COLLEGE;UK;/SOC;1;0;1;3;0;0 99225;275759;EthnographyOfRisk;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-IOF;FP7;Interdisciplinary advances on behavioural theories of financial risk-taking: Innovative insights from a video-ethnography of live trading in global reinsurance markets;2012-03-23;2015-03-22;;"This project will develop the applicant into a leader in the topic of social and material influences on financial risk-taking in the reinsurance industry. The reinsurance sector is dominated by European players that hold 64% of the industry’s global market share. Hence, in this sector, Europe must establish globalisation on its own terms, developing thought leaders to take their place on the world stage. The fellow has a unique dataset on this industry, of unparalleled scale and depth, comprising audio and video ethnography of live trading in 23 firms across the London, continental Europe and Bermuda markets. This dataset can be used to generate important interdisciplinary advances in behavioural theories of risk. However, there are few techniques for robust analysis of video data, requiring expanded skills and methodological innovation. She will therefore work with an interdisciplinary team of world-leading scholars in economic sociology, technology studies and ethnography at a top US university, Cornell, in order to generate the following results: 1. A book and academic papers built upon interdisciplinary frameworks at the intersection of economic sociology, technology studies and ethnography, which advance behavioural theories of risk-taking beyond current economics-based approaches. 2. Better understanding of how cultural variation in risk-trading practices shapes financial markets, which counteracts the Anglo-American assumptions that dominate existing theory. 3. Methodological innovation in ethnography, which requires a step change to meet the opportunities afforded by the increasing availability of portable digital video technology and home analysis software 4. Development of a rising European scholar into a thought leader on behavioural approaches to financial risk management, who comments knowledgably on the European reinsurance sector, and is internationally acknowledged for innovative methodological approaches to these important global issues.";313339,8;313339,8;FP7-PEOPLE-2010-IOF;/MC-IOF;CITY UNIVERSITY OF LONDON;UK;ASTON UNIVERSITY;UK;"/EMP;/SOC;/COO";1;0;1;3;0;0 88610;216065;GE.M.IC.;ONG;FP7-SSH;SSH-2007-3.3-01;FP7;Gender, Migration and Intercultural Interactions in the Mediterranean and South East Europe: an interdisciplinary perspective;2008-02-01;2011-01-31;;Ge.M.IC will study “Cultural Interactions in a European Perspective” through a tripartite conceptual and methodological approach, whose aim will be to identify links between migration, gender and intercultural interaction, as it is in the meeting place of these three dimensions that some of the most important cultural developments in Europe take place. Ge.M.IC will approach these questions from a critical perspective emphasizing in particular the impact of migrant mobility and cultural diversity on gender relation in host, transit and sending societies. Research will be of an interdisciplinary nature in accordance with the broad range of expertise of the researchers collaborating in the project. The organization of work will reflect the inter-ethnic and interdisciplinary character of the consortium focusing both fieldwork and analysis on six thematic areas of study, rather than on national case studies: representations of national identity and the media, education, urban social spaces and movements, religion, violence, and the family. Ge.M.IC will generate new and important insights in these thematic areas, taking advantage of the diverse areas of expertise of different researchers and their mutual commitment to studying gender and addressing issues of gender equality as a central aspect of research.;1309360;1019250;FP7-SSH-2007-1;/CP-FP;PANTEIO PANEPISTIMIO KOINONIKON KAIPOLITIKON EPISTIMON;EL;"UNIVERSITATEA DUNAREA DE JOS DIN GALATI;International Center For Minority Studies And Intercultural Relations;CONSORCI INSTITUT D'INFANCIA I MON URBA;INSTITUT ZA OPSTESTVENI I HUMANISTICKI ISTRAZUVANJA EVRO-BALKAN SKOPJE;Bilkent Üniversitesi;ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA;UNIVERSITY OF CYPRUS";"RO;BG;ES;MK;TR;IT;CY";/SOC;1;0;1;2;0;0 92711;238512;GATEWAYS;ONG;FP7-PEOPLE;FP7-PEOPLE-ITN-2008;FP7;Multi-level assessment of ocean-climate dynamics: a gateway to interdisciplinary training and analysis;2009-12-01;2013-11-30;;"GATEWAYS will conduct interdisciplinary climate change research on an ocean regime of regional and global significance: the Agulhas Current off southern Africa. It will provide 15 Early-Stage (ESR) and 3 Experienced Researchers (ER) with extensive multi-level scientific and complementary skills training in (1) processes relevant to climatic developments and projections, (2) efficient organization and management of interdisciplinary research, and (4) proficient transfer of information between the academic and private sectors. GATEWAYS will test the sensitivity of the Agulhas Current to changing climates of the past; the Current’s influence on southern Africa climates; buoyancy transfer to the Atlantic by ‘Agulhas leakage’ around southern Africa; and modulation of the Atlantic circulation by the leakage. Training encompasses novel laboratory-based methodologies; high-end equipment such as isotope-ratio and multi-sector inductively coupled plasma mass spectrometers; high-resolution climate modelling, accessing supercomputing facilities at national high-performance computing centres. Combined with the diverse scientific expertise converging on a common scientific theme, this provides the ESR and ER outstanding research training opportunities. Schools/workshops will deepen the insight gained and stimulate Network-wide discussion. Courses on project management, data processing and communication techniques will foster generic complementary skills. Secondments, longer stays at partner institutes and internships at SME partners add to the training. ESR and ER will acquire a solid knowledge in their own specialty field; a firm multi-level grounding in the marine and climate sciences; proficiency in analytical procedures and high-end numerical data processing and modelling; managerial skills to design and carry out research in an efficient and pragmatic way. This will boost their self-esteem and outlook for seeking attractive careers in research or allied areas in the future.";3663598,31;3663598,31;FP7-PEOPLE-ITN-2008;/MC-ITN;UNIVERSITAT AUTONOMA DE BARCELONA;ES;"STICHTING VU;STICHTING NIOZ, KONINKLIJK NEDERLANDS INSTITUUT VOOR ONDERZOEK DER ZEE;Climate Risk Analysis - Manfred Mudelsee;UNIVERSITY OF CAPE TOWN;CHRISTIAN-ALBRECHTS-UNIVERSITAET ZU KIEL;Ministry of National infrastructures;VERENIGING VOOR CHRISTELIJK HOGER ONDERWIJS WETENSCHAPPELIJK ONDERZOEK EN PATIENTENZORG;LEIBNIZ-INSTITUT FUER MEERESWISSENSCHAFTEN AN DER UNIVERSITAET KIEL;HELMHOLTZ ZENTRUM FUR OZEANFORSCHUNG KIEL;CARDIFF UNIVERSITY";"NL;DE;ZA;IL;UK";"/SCI;/EDU";1;0;1;2;0;0 95110;251336;ATOMICROBIOLOGY;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IEF;FP7;Elucidation of the architecture and dynamics of the bacterial cell wall by an interdisciplinary approach;2010-05-01;2012-04-30;;The fellowship will provide the researcher with a word class, career defining, interdisciplinary training in bacterial cell architecture and dynamics. The project is at the interface of biology, chemistry and physics, at an extremely timely moment at the forefront of technological developments. Peptidoglycan (PG) is the main component of the bacterial cell wall, crucial for cell shape and viability. PG is unique to bacteria and its importance is illustrated by the incredibly wide use of cell wall antibiotics such as penicillin and vancomycin. PG is a single macromolecule that surrounds the cell and whilst very strong, is also dynamic, allowing cells to growth and divide. Although the basic composition of PG is quite simple, its complex PG architecture has remained elusive. In a truly interdisciplinary approach the host institution has pioneered the application of high-resolution atomic force microscopy (AFM) to the study of PG architecture of the rod shaped bacterium, Bacillus subtilis. The initial work has provided exciting new and unexpected information, overturning previous models. A key question now arises as to how bacteria with different shapes solve their engineering problems of maintaining cell integrity whilst allowing growth? The researcher has a great pedigree in the study of the biochemistry of the PG of the ovococci (which include a number of important human pathogens). The architecture of the PG of the ovococci is currently unknown. Thus the project will be a fantastic synergy between the researcher and the host laboratory, providing cutting edge training, not only in the application of novel AFM techniques, but also in their development. Such a cross disciplinary project will lift the fellow to be at the forefront of research in the field worldwide. This will give him an ideal platform for his reintegration and establishment as a mature and successful scientist on the international stage.;239289,6;239289,6;FP7-PEOPLE-2009-IEF;/MC-IEF;THE UNIVERSITY OF SHEFFIELD;UK;;;"/SCI;/EDU;/ITT";1;0;1;2;0;0 95506;246536;INTERPOD;ONG;FP7-PEOPLE;FP7-PEOPLE-COFUND-2008;FP7;CRG International Interdisciplinary Postdoctoral Programme;2010-03-01;2015-04-30;;The current proposal aims at creating, at the Centre for Genomic Regulation (CRG), an International Interdisciplinary Postdoctoral Programme (InterPod) to train young scientists, in accordance with the objectives of the Marie Curie COFUND action. The goal of this new incoming mobility Programme is to provide highly talented postdocs with the opportunity to increase their trans-national mobility and advance their career development. CRG, located in the Barcelona Biomedical Research Park (PRBB), is emerging as a first-class multidisciplinary research centre. CRG strengths are in systems and computational biology, cell and molecular biology, genetics and epigenetics, and genomics and proteomics. CRG leads an International PhD Programme, hosts cutting-edge core facilities and gives access to one of the largest animal facilities in Europe. Therefore, the CRG will provide an excellent and dynamic scientific environment for the proposed Programme. The 4-year Programme will offer a total of 10 fellowships that will be announced in 2 international calls. The selection of the fellows will be merit-based, founded on international peer review in an open and transparent selection procedure. The fellows will choose interdisciplinary research projects that bring together research lines of two or more CRG laboratories. In addition to advanced research training, the Programme will offer a series of activities and workshops aimed at providing experienced researchers with the required skills for a successful career in science, and increase their competitiveness in the current job market.;1587900;635160;FP7-PEOPLE-COFUND-2008;/MC-COFUND;FUNDACIO CENTRE DE REGULACIO GENOMICA;ES;;;"/ECO;/REG;/INF";1;0;1;2;0;0 91074;230602;PHM-ETHICS;ONG;FP7-SIS;SiS-2008-1.1.2.1;FP7;Personalized health monitoring (PHM)- Interdisciplinary research to analyse the relationship between ethics, law and psychosocial as well as medical sciences;2009-07-01;2012-06-30;;The aim of PHM-Ethics is to scientifically analyse the dependencies between ethics, law and psychosocial sciences in a dynamic part of IT development, i.e. personalized health monitoring (PHM), from a European perspective. First, the development of PHM will be reviewed to identify core steps that delineate major changes from an ethical, legal and psychosocial point of view. A taxonomy will be elaborated based on research evidence in each of the disciplines, and interrelations will be documented into a map. The project will be situated at the development phase of new technologies, however also at the early application phase. As a major step, the implementation of ethical constraints contained in EU/ international instruments into the national laws or regulations will be analysed, and gaps will be identified. At the end of project phase 1, the taxonomy will be validated in an international expert workshop. The aims of the second project phase are to develop and test an interdisciplinary methodology that allows assessing PHM technologies regarding their ethical, legal and psychosocial consequences. The interdisciplinary methodology will be pilot-tested on a qualitative basis and validated in selected personal health monitoring applications at different stages of the taxonomy. The objective of the study is to gain scientific input from the patient and provider point of view. Results of an empirical study will be analysed in terms of differences between development stages and socio-demographic factors. The third project phase is related to the exploitation of knowledge and research products, with regard to policy-making and implementation of technological innovations. PHM-Ethics will provide a tool that allows studying future PHM applications on different taxonomic levels concerning their consequences to serve both internal and external dissemination purposes within the 7th framework, also projecting the methodology to other technological field (e.g. the security area).;1267351;998113;FP7-SCIENCE-IN-SOCIETY-2008-1;/CP;UNIVERSITAET GREIFSWALD;DE;"Advocatenkantoor Callens Burg. Venn. met de vorm van een BVBA;LINKOPINGS UNIVERSITET;INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE;DE MONTFORT UNIVERSITY;UNIVERSITEIT UTRECHT;UNIVERSITAETSMEDIZIN GOETTINGEN - GEORG-AUGUST-UNIVERSITAET GOETTINGEN - STIFTUNG OEFFENTLICHEN RECHTS";"BE;SE;FR;UK;NL;DE";"/ETH;/SCI";1;0;1;2;0;0 86245;205872;POSTBIOMIN;ONG;FP7-REGPOT;REGPOT-2007-1-01;FP7;Program developing interdisciplinary research POtential for the STudies of BIOMolecular INteractions;2008-03-01;2011-08-31;;National Centre for Biomolecular Research (NCBR), Masaryk University Brno in the Czech Republic has become one of the leading laboratories for structural biology in the Central Europe. The institute is very well equipped by modern laboratory equipment and instruments. It has established a competitive research program in structural biology through extramural funding from agencies such as the Wellcome Trust, Howard Hughes Medical Institute, European Molecular Biology Organization, 6th FP, Ministry of Education of the Czech Republic or Grant Agency of the Czech Republic. The institute has several teams pursuing both theoretical and experimental research that focuses on the structural characterization of biomacromolecules. NCBR is now trying to refocus its research interest to biomolecular interactions study. That is essential for understanding how molecular machines operate in cells. To establish a competitive research program in biomolecular interactions has proven to be difficult in the Central Europe as the vast majority of know-how and expertise operate in “traditional” EU countries. Project POSTBIOMIN will strengthen our research potential through the scheme of support measures like recruitment of foreign experts, organization of international PhD courses and lectures given by top international scientists. Series of workshops, seminars, postdoctoral and expert inter-ships and visits will be organized. We suppose to reinforce our capacities related to transfer of technologies by hiring the West European specialist. This program will complement investments in research capacity co-financed through the EU cohesion policy programmes for 2007-2013, i.e., CEITEC - large project of Centro-European Institute of Technology focuses on biotechnologies and interdisciplinary medical research, and is prepared in Brno with political support of the Czech Government.;1177360;1049921;FP7-REGPOT-2007-1;/CSA-SA;Masarykova univerzita;CZ;;;/POL;1;0;1;1;0;0 91832;236575;PROMOTE;ONG;FP7-PEOPLE;FP7-PEOPLE-IEF-2008;FP7;The provenance of mosaic tesserae: an interdisciplinary study on Roman Age glass production and trade in Italy;2009-09-01;2011-08-31;;This project is an interdisciplinary research aimed to improve the knowledge of the Roman age glassmaking industry. The existing reconstruction of the economic model of the ancient glass production derives from the archeological and archaeometric literature and hypothesizes a productive system divided in three phases: firstly the base glass production in few primary glassmaking centers, located in Egypt and in the Near East, in the second stage base glass trading and, finally, the shaping of objects in secondary glass-working centers. Italy lacks in primary glassmaking evidences, but it was demonstrated the suitability of Campania coastal sands to make glass. The problem of location of the primary productive centers and the reconstruction of the trading routes is an open question and this work is aimed to give a contribution for its solution. A specific geographical area, a peculiar type of vitreous materials and a lapse of time were chosen in order to work efficiently. The research is focused in Italy and the materials are the vitreous mosaic tesserae dating from 3rd century BC to 2nd century AD, a meaningful period for the mosaic history. Glass tesserae will be compared to raw materials from Campania and Egypt, the last being a region with a long story of glassmaking tradition and strictly linked to Roman Italy. The characterization will be focused on the analytical techniques useful to trace the provenance of the materials: the stable isotope and the trace elements analysis. Such a kind of characterization is at an initial stage and different techniques will be tested to optimize an effective analytical procedure. The objectives of this work will be improving the knowledge of ancient vitreous materials, experiencing a work procedure to apply the trace and isotope analysis to the ancient glasses and clarifying the origin of the Italian Roman age glasses.;;171867,63;FP7-PEOPLE-IEF-2008;/MC-IEF;THE UNIVERSITY OF NOTTINGHAM;UK;;;"/SCI;/EMP";1;0;1;1;0;0 100819;284126;KONGOKING;ONG;FP7-IDEAS-ERC;ERC-SG-SH6;FP7;Political centralization, economic integration and language evolution in Central Africa: An interdisciplinary approach to the early history of the Kongo kingdom;2012-01-01;2016-12-31;;The magnificent Kongo kingdom, which arose in the Atlantic Coast region of Equatorial Africa, is a famous emblem of Africa’s past. It is an important cultural landmark for Africans and the African Diaspora. Thanks to its early introduction to literacy and involvement in the Trans- Atlantic trade, the history of this part of sub-Saharan Africa from 1500 onwards is better known than most other parts. Nevertheless, very little is known about the origins and earlier history of the kingdom. Hence, this grant application proposes an interdisciplinary approach to this question. Archaeology and historical linguistics, two key disciplines for early history reconstruction in Africa, will play the most prominent role in this approach. Paradoxically, if the wider region of the Kongo kingdom is one of the best documented areas of Central Africa from a historical and ethnographic point of view, it is virtually unknown archaeologically. The proposed research team will therefore undertake pioneer excavations in several capital sites of the old kingdom. Similarly, no comprehensive historical study has covered the languages of the Kongo and closely affiliated kingdoms. Nonetheless, the earliest documents with Bantu data, going back to the early 16th century, originate from this region. The proposed research team will therefore undertake a historical-comparative study of the Kikongo dialect cluster and surrounding language groups, such as Kimbundu, Teke and Punu-Shira, systematically comparing current-day data with data from the old documents. Special attention will be given to cultural vocabulary related to politics, religion, social organization, trade and crafts, which in conjunction with the archaeological discoveries, will shed new light on th;1400760;1400760;ERC-2011-StG_20101124;/ERC-SG;UNIVERSITEIT GENT;BE;"UNIVERSITE LIBRE DE BRUXELLES;MUSEE ROYAL DE L'AFRIQUE CENTRALE";BE;"/SCI;/SOC";1;0;1;1;0;0 89246;231519;e-LICO;CLO;FP7-ICT;ICT-2007.4.4;FP7;e-Laboratory for Interdisciplinary Collaborative Research in Data Mining and Data-Intensive Sciences;2009-02-01;2012-01-31;;"The goal of the e-LICO project is to build a virtual laboratory for interdisciplinary collaborative research in data mining and data-intensive sciences. The proposed e-lab will comprise three layers: the e-science and data mining layers will form a generic research environment that can be adapted to different scientific domains by customizing the application layer. The e-science layer, built on an open-source e-science infrastructure developed by one of the partners, will support content creation through collaboration at multiple scales and degrees of commitment---ranging from small, contract-bound teams to voluntary, constraint-free participation in dynamic virtual communities. The data mining layer will be the distinctive core of e-LICO; it will provide comprehensive multimedia (structured records, text, images, signals) data mining tools. Standard tools will be augmented with preprocessing or learning algorithms developed specifically to meet challenges of data-intensive, knowledge rich sciences, such as ultra-high dimensionality or undersampled data. Methodologically sound use of these tools will be ensured by a knowledge-driven data mining assistant, which will rely on a data mining ontology and knowledge base to plan the mining process and propose ranked workflows for a given application problem. Extensive e-lab monitoring facilities will automate the accumulation of experimental meta-data to support replication and comparison of data mining experiments. These meta-data will be used by a meta-miner, which will combine probabilistic reasoning with kernel-based learning from complex structures to incrementally improve the assistant's workflow recommendations. e-LICO will be showcased in a systems biology task: biomarker discovery and molecular pathway modelling for diseases affecting the kidney and urinary pathways.";4468853;3417403;FP7-ICT-2007-3;/CP;UNIVERSITE DE GENEVE;CH;"POLITECHNIKA POZNANSKA;INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE;THE UNIVERSITY OF MANCHESTER;INSTITUT JOZEF STEFAN;MEDICEL OY;UNIVERSITAT ZURICH;RAPIDMINER GMBH;ETHNIKO IDRYMA EREVNON;RUDER BOSKOVIC INSTITUTE";"PL;FR;UK;SI;FI;CH;DE;EL;HR";"/IPS;/INF;/TEL";1;0;1;1;0;0 105534;316978;TS-EUROTRAIN;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-ITN;FP7;"Interdisciplinary training network for Tourette Syndrome; structuring European Training capacities for neurodevelopmental disorders";2012-10-01;2016-12-31;;There is a striking lack in structured and standardized training infrastructure for neurodevelopmental disorders across Europe. Such training will be fundamental to promoting standards of care across Europe and will ultimately lead to strategies for the promotion of childhood mental health in Europe. The focus of this Initial Training Network (ITN) is Gilles de la Tourette Syndrome (TS), an inherited neuropsychiatric disorder that provides an excellent paradigm for the study and training needs for neurodevelopmental disorders of childhood onset. TS is marked by multiple motor and vocal tics and high comorbidity rates with attention deficit hyperactivity disorder and obsessive compulsive disorder. Due to lack of education of medical professionals, educators, and the general public, TS is underdiagnosed and patients are severely discriminated against. Efforts to elucidate the etiology and pathophysiology of TS are fragmented across Europe and hampered by low statistical power. Standards of care are not uniform due to lack in structured training modules for this disorder. We have built an comprehensive interdisciplinary and intersectorial training program in the field of TS and related disorders, that will deliver the next generation of young researchers who will shape the field in Europe and around the world. Their research within this ITN will lead to discoveries that will ultimately provide new therapies and increase the quality of life for patients and their families. At the same time, their engagement to society will increase awareness about the disorder in a pan-European effort to promote childhood mental health across Europe.;3076397,9;3076397,9;FP7-PEOPLE-2012-ITN;/MC-ITN;DEMOCRITUS UNIVERSITY OF THRACE;EL;"KENNEDY CENTRET;REGION HOVEDSTADEN;STICHTING KATHOLIEKE UNIVERSITEIT;UNIVERSITAET ULM;ACADEMISCH ZIEKENHUIS GRONINGEN;MEDIZINISCHE HOCHSCHULE HANNOVER;ISLENSK ERFDAGREINING EHF;BOEHRINGER INGELHEIM PHARMA GMBH &CO KG;SEMMELWEIS EGYETEM;UNIVERSITEIT UTRECHT";"DK;NL;DE;IS;HU";/LIF;1;0;1;1;0;0 185502;607930;INTREPID Forensics;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-ITN;FP7;Interdisciplinary Training and Research Programme for Innovative Doctorates in Forensic Science;2014-04-01;2018-03-31;;"The INTREPID Forensics programme will provide opportunities for students to pursue innovative PhD research degrees focusing on areas in the forensic sciences. Forensic-related research topics are difficult to study comprehensively at PhD level, due to the inherent interdisciplinary nature of these enquires. High quality supervision of such projects, which are aligned with the occupational standards of forensic practitioners and researchers, requires expertise from both a legal/criminological perspective as well as a physical sciences specialism. Traditionally, bridging this divide between the social, legal, and physical sciences has not been possible for prospective PhD students. The United Kingdom, and the University of Leicester in particular, has a strong history of world class forensic research and innovation and this proposed innovative doctoral programme would attract high quality early career researchers to investigate forensic technologies with the potential to impact crime across Europe and globally. The University of Leicester hosts the 'Alec Jeffreys Forensic Science Institute' which serves as a central facilitator of forensic research and teaching across the disciplines and colleges. By bringing these disciplines together, and engaging with industry and European partners, the institute has the ability to offer innovative PhD opportunities to students who wish to research forensic topics. Such projects will be supervised by leading academic researchers from a variety of disciplines, and are designed to overcome traditional boundaries between the physical and social sciences. Students will benefit from expertise across the relevant disciplines, the faculty will be given the opportunity to engage with colleagues through joint supervision which would not normally be possible, and the forensic services industry will ultimately find graduates of this programme to be better prepared for a career in forensic science research, innovation and practice.";2935916,5;2935916,5;FP7-PEOPLE-2013-ITN;/MC-ITN;UNIVERSITY OF LEICESTER;UK;;;/LIF;1;0;1;1;0;0 107819;318718;IMCONET;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IRSES;FP7;Interdisciplinary Modelling of Climate Change in Coastal Western Antarctica - Network for Staff Exchange and Training;2013-02-01;2017-01-31;http://www.imconet.eu/;"The proposed European-US and South American network IMCONet will advance climate and (eco-) system change research at the Western Antarctic Peninsula (WAP), a region of recent rapid aerial warming. WAP glaciers contribute to global sea level rise, and functioning and services of coastal ecosystems are massively threatened by the fast regional warming. Data sets from recent interdisciplinary European-South American field work within ESF-IMCOAST (PolarCLIMATE April 2010-March 2013) and from the Jubany scientific core programme at King George Island (KGI) will be connected and cross-validated with southern stations on WAP: the US Palmer and the British Rothera station. Links with both stations and program leaders (Ducklow, CU, New York, US (formerly at MBL Woods Hole,US); and Meredith, NERC-BAS, Cambridge, UK) have been established in IMCOAST. IMCONet objectives are A) to develop predictive climate change and ecosystem models for the whole WAP coastal environment based on existing data sets and data exchange policies, B) transfer of knowledge between partner countries to enhance collaboration with high quality long-term measuring programs at all 3 stations, to fill present measuring gaps. This will solidify the basis for the prediction of climate change effects in the South. The proposed consortium consists of 16 institutional partners across 10 countries with 85 travelling scientists. Ten partners already collaborate successfully as EU and associated teams in ESF-IMCOAST, and IMCONet will be coordinated by the same PI (Abele, AWI). Whereas ESRs are seconded mostly for longer training and collaboration periods, exchange of ERs will also foster joint teaching in the partner countries and collaboration in future science projects. The concept of IMCONet is to strengthen European engagement in Antarctic climate change research, as complementing approach to the major EU focus in the Arctic. It will sustain ongoing European Antarctic research in a future network with competent South American partners.";858900;858900;FP7-PEOPLE-2012-IRSES;/MC-IRSES;ALFRED-WEGENER-INSTITUT HELMHOLTZ-ZENTRUM FUR POLAR- UND MEERESFORSCHUNG;DE;"FRIEDRICH-ALEXANDER-UNIVERSITAET ERLANGEN NUERNBERG;UNIVERSITEIT GENT;AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS;RIJKSUNIVERSITEIT GRONINGEN;CARL VON OSSIETZKY UNIVERSITAET OLDENBURG;GOETEBORGS UNIVERSITET;NATURAL ENVIRONMENT RESEARCH COUNCIL";"DE;BE;ES;NL;SE;UK";/SCI;1;0;1;1;0;0 96442;254618;INTERPITCH;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IEF;FP7;Interdisciplinary investigation of Pitch coding in whispered speech;2011-01-01;2012-04-30;;The goal of the InterPitch project is to systematically investigate how intonation (speech melody) is coded in whispered speech. A speaker who whispers fails to produce the most important cue to intonation perception, i.e. the fundamental frequency (F0). Assuming that the speaker attempts to accommodate the listener during communication, the whispering speaker is expected to naturally compensate for the loss of that cue by exploiting (and exaggerating) alternative acoustic cues to pitch. The project will investigate both the presence and nature of cues to intonation in whispered speech, and their relevance for listeners. The project will take an interdisciplinary approach by combining acoustic-phonetics, “the production perspective”, and psychoacoustics, “the perception perspective”. This captures the full speech chain, i.e. the model of how a message is transferred from the mind of the speaker to the mind of the listener. The test case will be Clause Typing, i.e. signaling whether a sentence is a question or a statement through intonation. This phenomenon is found in many European languages in similar ways. Through extensive psychoacoustic and phonetic analyses of whispered and phonated speech the contents of the speech signal in both questions and statements will be investigated. Through perception tests the specific contribution of temporal coding to intonation perception will be studied, and the availability of acoustic cues to hearing impaired listeners will be simulated. The results contribute to understanding the fundamental relation between mental representations of language and their realisations in both regularly phonated and whispered speech. The results may furthermore be used for synthesis of whispered speech, which has applications in text-to-speech systems, and for new ways of coding pitch information in cochlear implant processors for hearing impaired populations.;101761,4;101761,4;FP7-PEOPLE-2009-IEF;/MC-IEF;ECOLE NORMALE SUPERIEURE;FR;;;"/SCI;/EDU;/ITT";1;0;1;1;0;0 90114;200267;CELTICNIGHT;ONG;FP7-PEOPLE;PEOPLE-2007-5-1.NIGHT;FP7;The Celtic Night - On-site Presentation of Interdisciplinary Archaeological Research and Archaeological Science;2007-06-01;2008-01-31;;The excellence research platform of the University of Vienna VIAS -Vienna Institute for Archaeological Science proposes the CelticNight, an on-site presentation of state-of-the-art interdisciplinary archaeological research and archaeological science on a 15 ha Celtic pre-urban site south of Vienna. The site provides an on-going international excavation using latest 3D laser scanners for complete digital documentation, a reconstructed part of the Celtic town integrated in a new archaeological park co-funded by the EC, an exhibition tower and a festival site with all infra-structure needed for mass events. Previous experience (10 years Celtic open-air festivals combining archaeology and music, the archaeological park, special children and family programs) proved to attract up to 8500 people per weekend. We intend to setup up a living archaeology experience for the audience, providing a research path integrating an excavation show-case, a field laboratory presenting Archaeological Science, experimental workshops focussing on Celtic production processes from rawmaterial to tools in action, a re-enactment of Celtic daily live in the reconstructed buildings, a movie stage presenting broadcasts and documentaries of previous on-site research ending up in the Celtovation music festival presenting bands performing music with Celtic roots. VIAS intends to present Archaeological Research and Science bringing together about 70 archaeologists, scientists, communal representatives, regional management and SME´s on one of the most important Celtic archaeological sites in Eastern Austria to popularise living archaeology. The planned activities will provide an additional impact on tourism and local economy, enforcing the importance of research and science for cultural tourism as a future concept for regional development.;65170;65170;FP7-PEOPLE-2007-5-1-1-NIGHT;/CSA-SA;UNIVERSITAT WIEN;AT;"Institut für Ur- und Frühgeschichte;Community of Schwarzenbach";AT;/SCI;1;0;1;1;0;0 90639;235766;LALSUS;ONG;FP7-PEOPLE;FP7-PEOPLE-IIF-2008;FP7;LEARNING AND LIVING SUSTAINABLY: Building Interdisciplinary Research Capacity and Expertise in Social and Professional Responses to Sustainability at the University of Gloucestershire;2009-05-01;2011-05-31;;"Sustainability, and engagement with it, has become one of the biggest challenges we face in the 21st Century. Unsustainable practices are increasing the impact of environmental degradation, extending inequalities in our society and across the globe as well as limiting quality of life. The University of Gloucestershire has an institutional commitment to Sustainable Development. The University has modelled sustainability in its operational, administration and management structures. The University is now seeking to invest in and support staff so that existing research strengths explore a common platform in the area of people learning and engagement for sustainability. It also recognizes the importance of embedding sustainability into the curriculum and the lack of pedagogical and research capacity in this area. The purpose of this proposal is to bring external expertise necessary to develop research capacity in social and professional action for sustainability. The programme seeks to: (i) embed sustainability as a cross-cutting research strand at the University of Gloucestershire through training and networking opportunities in interdisciplinary social science research; (ii) conduct flagship research in a crucial multifaceted area which can inform sustainable living; (iii) conduct pedagogical research which can assist in embedding sustainability into the learning experiences of students at the University of Gloucestershire.";239952,41;239952,41;FP7-PEOPLE-IIF-2008;/MC-IIF;UNIVERSITY OF GLOUCESTERSHIRE LBG;UK;;;"/SCI;/EMP";1;0;1;1;0;0 103387;298285;PAST FRAGMENTS;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IEF;FP7;Materiality and depositional practices in the later Prehistory in Europe: an interdisciplinary approach using central Iberia (Spain) record as a case study;2012-05-01;2014-04-30;;'The vast majority of European archaeological heritage during later Prehistory consists in ephemeral, scattered and scarcely stratified evidence. The research agenda on this topic lacks disciplinary debate and is based on out-of-date, isolationist and stagnant perspectives. This research proposal constitutes an advanced training-through-research project, which aims to invigorate and update the theoretical and methodological approaches applied to these issues, challenging several taken-for-granted assumptions through a non-positivist and non-determinist viewpoint. These goals will be reached through a timely work plan which implements a multi-scalar, diachronic strategy focused on central Iberia archaeological record as a case study, and is designed to integrate two complementary and interlinked scales of enquiry: 1) a micro-scale approach to material culture (taphonomic, use-wear, erosion and archaeometric studies) and 2) a macro-scale focus on the spatial dimension of connectivity between people, things and places (re-fitting studies). Data will be collected for Bell Beaker and Later Bronze Age pottery (2600-1000 BC) to provide technological, cultural “biographical” and depositional information from several well-documented case studies, thus characterising the social practices involved in their production, use and discard (e.g. their deliberate fragmentation and dispersion across the landscape). The use of Geographic Information Systems and inferential statistics will improve the testing of innovative hypotheses at both intra-site and inter-site levels, to complement the available functional and stylistic data. Thus, the study of the actual technological skills, lifespan trajectories, and depositional patterns (both intentional and unintended) involved in the formation of the later prehistoric materiality, will allow to reassess the meaning of pan-European phenomena like pit digging or the Beaker as active participants in these cultural practices';209033,4;209033,4;FP7-PEOPLE-2011-IEF;/MC-IEF;UNIVERSITY OF DURHAM;UK;;;/SCI;1;0;1;0;0;0 187754;623293;TROPICMICROARCH;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IEF;FP7;"Tropical Micro-Archaeology: An interdisciplinary project aiming to study site formation processes in tropical environment related to hunter-gatherers' use of space";2015-01-01;2016-12-31;;"TropicMicroArch aims to study how hunter-gatherers' ways of living are reflected in their use of space and how it affects the depositional processes of microscopic materials in tropical forests. Although hunter-gatherers' use of space has previously been studied through Ethnoarchaeology, this project proposes to study it from a new microscopic perspective with special attention given to post depositional processes. In comparison to arid, semi-arid and temperate environments, site formation processes at tropical forest open air sites have not yet been studied in detail. This project will develop methods of sediments sampling and mapping and methods of laboratories analyses of microscopic remains which will aid the archaeological research to analyze the use of space among prehistoric hunter-gatherers and to understand and observe formation processes in tropical sites. This will be achieved by conducting ethnographic and geoarchaeological fieldwork, geochemical analyses and spatial mapping. Fieldwork will centers on living and abandon settlements of a contemporary hunter-gatherer community in the tropic forests of South India. Research will take place in the McDonald Institute for Archaeological Research in the University of Cambridge, where the integration of humanities, social sciences and exact sciences is possible. Due to its multidisciplinary properties, this study will involve several host scientists and mentors from the Department of Anthropology and Archaeology at Cambridge University, in addition to collaboration with researchers from other departments and institutes from Europe and Asia. The fellow will benefit from the interplay and integration of scientific practice and theory in Cambridge University. He will gain invaluable training and experience as a member of the McDonald Institute and the McBurney Laboratory for Geoarchaeology, where many studies related to hunter-gatherers and tropical environments are currently being held.";231283,2;231283,2;FP7-PEOPLE-2013-IEF;/MC-IEF;THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;UK;;;;1;0;1;0;0;0 106953;322920;POSTTRANS;ONG;FP7-IDEAS-ERC;ERC-AG-LS2;FP7;An interdisciplinary genome-wide study of posttranscriptional regulation by small RNAs: from individual interactions to networks and evolution;2013-02-01;2019-01-31;;Deciphering the interactions within and between the three major components of living organisms, DNA, RNA and Protein, is at the heart of biological research. New large-scale experimental methods have dramatically advanced genome-wide detection of protein-protein, protein-DNA, protein-RNA and protein-mediated RNA-RNA interactions. However, at present there is no large-scale method that could detect all RNA-RNA interactions independent of a mediator protein, or when the mediator protein is unknown. Attaining such a method is of utmost importance and is very timely, as it is now evident that RNA-RNA interactions play central roles in cellular life. In particular, hundreds of expressed small RNA (sRNA) molecules were discovered in both pro- and eukaryotes, many of which act as posttranscriptional regulators of gene expression by base-pairing with their mRNA targets. It seems that in many organisms the layer of posttranscriptional regulation is as widespread as transcription regulation, presenting a major challenge towards achieving functional and mechanistic understanding of this regulation level. Here we propose to develop an innovative methodology for genome-wide detection of the sRNA targetome, all mRNA targets of cellular sRNAs. This new methodology combines in vivo structural probing with deep sequencing and is independent of protein considerations. We will apply this method to deciper the sRNA targetome of the model organism Escherichia coli, which encodes over 100 sRNAs. We will use the sRNA targetome data as the foundation for a systematic ‘bottom-up’ computational analysis of multifaceted aspects of sRNA-mediated posttranscriptional regulation, encompassing the basic underlying rules of sRNA-mRNA target recognition, the design principles of the posttranscriptional regulatory network and its integration with the transcriptional and metabolic networks, and the evolution of posttranscriptional regulation.;2329360;2329360;ERC-2012-ADG_20120314;/ERC-AG;THE HEBREW UNIVERSITY OF JERUSALEM;IL;;;"/BIO;/LIF";1;0;1;0;0;0 97776;256555;URBEN;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-RG;FP7;Linking urban design and health issues: an interdisciplinary approach;2011-05-02;2015-05-01;;Darchen in Tibet is a small town situated at the foot of the holy mountain Kailas, which lies near the source of five of Asia’s most significant rivers. The town has been expanding steadily over the last decade through the growing influx of pilgrims and tourists, which is expected to increase exponentially in the next few years. Concomitant economic growth is causing significant lifestyle changes for the population of Darchen. However, the town, situated in a semi-arid region, is already facing serious environmental issues due to a lack of water and sanitation infrastructure. Problems include inadequate supply of drinking water, water pollution, lack of waste water and solid waste management, rubbish dumping, etc. Further, the inhabitants of the town face a number of health issues, which may be partially related to inadequacy and pollution of drinking water. The aim of this study is to analyze the relation between water management and health issues, and to identify urban design solutions which may be appropriate to tackling the water management problem. The premise is that an analysis of health issues may visualize to policy and decision makers the advantages of urban infrastructure investment enabling adequate and clean drinking water supply in Darchen. Further, the research can serve to inform Eco-town models for the future development of other towns in the same region.;100000;100000;FP7-PEOPLE-2009-RG;/MC-IRG;TECHNISCHE UNIVERSITAET MUENCHEN;DE;RHEINISCHE FRIEDRICH-WILHELMS-UNIVERSITAT BONN;DE;/SCI;1;0;1;0;0;0 89728;224091;GLOBALCHANGEBIOLOGY;ONG;FP7-PEOPLE;PEOPLE-2007-4-3.IRG;FP7;A physiologically-based weather-driven geospatial modelling approach to global change biology: tackling a multifaceted problem with an interdisciplinary tool;2008-11-01;2012-10-31;;Analytical tools that provide a synthesis of ecological data are increasingly needed to design and maintain sustainable agroecosystems increasingly disrupted by global change in the form of agro-technical inputs, invasive species, and climate change. This is particularly relevant to the Mediterranean Basin, a climate change hot-spot already threatened by local environmental changes including desertification. The project will provide important tools for summarizing, managing, and analyzing ecological data in agricultural systems to address global change effects using grape and olive as model systems. The project will integrate weather driven physiologically based Ecosystem Modelling (EM) and Geographic Information Systems (GIS) to derive a dynamic understanding of complex agricultural systems in the face of global change including climate warming. Multivariate analyses will be used to summarize the main effect of model predictions in a space and time independent way to provide a solid but flexible basis for managing Mediterranean grape and olive systems in a changing global environment. The integrated EM/GIS system may be viewed as a library of the current knowledge about agroecosystems that can be extended to other systems, updated with new knowledge and used to help guide multidisciplinary research on local and regional scales. The need for extensive weather datasets to drive the models requires that the EM/GIS technology be linked with remote sensing (RS) to enhance spatial resolution of the approach and increase its real-world applications. This combined innovative EM/GIS/RS tool will provide European governmental agencies with the scientific basis for developing policy required to adjust to global change including climate warming.;100000;100000;FP7-PEOPLE-2007-4-3-IRG;/MC-IRG;AGENZIA NAZIONALE PER LE NUOVE TECNOLOGIE, L'ENERGIA E LO SVILUPPO ECONOMICO SOSTENIBILE;IT;;;"/SCI;/COO";1;0;1;0;0;0 90819;221054;MAGMA;ONG;FP7-PEOPLE;PEOPLE-2007-4-1.IOF;FP7;Mass transfer of metals and sulfur between mafic silicate melts and volatiles: an interdisciplinary approach;2008-11-15;2011-11-14;;A systematic experimental study will be conducted to obtain quantitative information on the distribution of Cu, Au and S between andesitic and basaltic silicate melts and volatile phases. The experiments will be carried out in cold seal and internally heated pressure vessels, at various conditions characteristic of upper crustal magma reservoirs. The fluid phase will be trapped as synthetic fluid inclusions in mafic minerals or in fine grained mineral traps at the experimental run conditions. The chemical composition of the phases and the speciation of the elements will be analyzed using LA-ICPMS and X-ray Absorption Spectroscopy, respectively. From these data, the partition coefficients of S, Cu and Au between the fluid and the melt will be calculated and interpreted in a thermodynamic framework. The results will be used to build mass transfer models to assess the efficiency of the spatial redistribution of S, Cu and Au through volatiles within complex magmatic reservoirs at various physical and chemical conditions. These models will lead to a better understanding of processes responsible for formation of porphyry-type ore deposits and the controls on the composition of emitted gases by active volcanoes.;237981,03;237981,03;FP7-PEOPLE-2007-4-1-IOF;/MC-IOF;EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH;CH;;;"/SCI;/COO";1;0;1;0;0;0 111609;609431;INDICAR;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-COFUND;FP7;Interdisciplinary Cancer Research;2013-12-01;2018-11-30;;"'The crucial role of postdoctoral fellows for the advancement of science and innovation is well understood at the University of Vienna. In order to further strengthen their role as critically thinking, independent, autonomous and risk taking researchers and innovators, who will contribute to the benefit of academia and society at large, the University of Vienna will launch an initiative, the INDICAR Postdoctoral Fellowship Programme, to promote a new vision of postdoctoral training in the field of cancer research. Moreover the Programme will combine fundamental and application-oriented research, rendering the University and thus Europe, highly attractive for the sharpest minds. The INDICAR Programme is led by the conviction that an internationally attractive postdoctoral fellowship must provide an excellent postdoctoral experience, including a well-developed research capability; additional training in areas of importance to the career development of the INDICAR fellow; an enhanced research network; international exposure; publications in high profile journals; and excellent career prospects. Moreover, the INDICAR Programme will cover a wide spectrum of research areas relevant for the European Research Area such as biology, bioinformatics, chemistry, physics, nursing science, pharmaceutical sciences and nutritional sciences. The University supports the possibility to develop an independent research project and provides mentoring, coaching and career development activities, in addition to optimal employment conditions, a competitive salary and family support.'";3848976;1539590,4;FP7-PEOPLE-2013-COFUND;/MC-COFUND;UNIVERSITAT WIEN;AT;;;/LIF;1;0;1;0;0;0 99135;267499;INTERCOCOS;ONG;FP7-IDEAS-ERC;ERC-AG-PE2;FP7;Interdisciplinary research: Connecting complex plasmas with colloidal dispersions;2011-06-01;2016-05-31;;"This proposal represents the first concerted effort to study classical strongly coupled systems at the most fundamental individual-particle level, by using complementary approaches from different physics domains - complex plasmas and colloidal dispersions. These are complementary in many ways, the most important being that complex plasmas are virtually undamped at the particle timescales, whereas colloidal dispersions are overdamped and thus can be brought into equilibrium in a controlled way. Otherwise, both fields have similar advantages: Fully resolved 3D particle trajectories can easily be visualized, the pair interactions are tunable, and particles can be manipulated individually or collectively. The principal scientific aim is to study generic dynamical and self-organization processes at a detail not possible in the past. Scientific objectives include 1) particle dynamics of liquids, with the emphasis on mesoscopic processes in the supercooled state, e.g. dynamical heterogeneity, 2) phase transitions in solids, with particular attention on the evolutionary paths of crystal structure development and defect dynamics, 3) non-equilibrium phase transitions, with the focus on lane formation in driven binary systems and the dynamics at “atomistic” timescales, 4) phase separation in binary fluids, with the emphasis on the role of pair interactions in the demixing kinetics, as well as in the transition between spinodal decomposition and nucleation and growth regimes, 5) hydrodynamics at the discreteness limit, especially the onset and development of hydrodynamic instabilities at the particle scale, and 6) critical phenomena in particle systems with “designed” pair interactions, where the range and strength of attractive/repulsive parts can be tuned by external fields.";2119800;2119800;ERC-2010-AdG_20100224;/ERC-AG;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;DE;HEINRICH-HEINE-UNIVERSITAET DUESSELDORF;DE;"/PSE;/SCI";1;0;1;0;0;0 97062;260309;PRESTIGE;ONG;FP7-HEALTH;HEALTH.2010.2.4.2-1;FP7;PREvention of Late Stent Thrombosis by an Interdisciplinary Global European effort;2010-12-01;2014-11-30;http://www.prestige-fp7.eu/index.php?id=267;"According to the European Society of Cardiology there has been an increase in the life expectancy at the age of 65 of the European population from 15.0 to 17.0 years in the years since 1980. In the elderly, up to 50% of deaths are caused by cardiovascular diseases, the majority accounted for by coronary artery disease. The most effective treatment for obstructive coronary disease is percutaneous intervention with coronary stenting and fuelled by the increasing disease burden there has been a rapid increase in the number of percutaneous coronary intervention procedures in Europe from 184,000 in 1992 to 885,000 in 2004. If the rate of progression remains constant, the projected number of coronary intervention procedures per annum will be about 1.5 million by 2010, with a stenting rate of close to 100%. The principal safety issue with current coronary stenting procedures is late stent thrombosis which, with a case mortality rate approaching 50%, makes this problem a very significant European health issue. The PRESTIGE project will result in significant improvement in prediction and prevention of late stent thrombosis by providing novel strategies that causally impede incident events without increasing the overall risk of bleeding. These goals will be achieved by a multidisciplinary consortium formed by world-leading EU-based specialists covering the requisite scientific skills and experience. Since the first drug-eluting stent was introduced in 2002 the growth of this sector has been explosive. Forecasts predicted the potential for this market segment to exceed €4.6 billion by 2009. The economic impact of this very ambitious project will be to provide the European health industries with novel stent products and new imaging technologies to identify patients at-risk, as well as amended European treatment guidelines. The social impact will be, amongst others, a tremendous cost reduction for the public and private health insurance systems all over Europe.";7981609,2;5979641,5;FP7-HEALTH-2010-single-stage;/CP-FP;DEUTSCHES HERZZENTRUM MUNCHEN;DE;"SAMODZIELNY PUBLICZNY ZAKLAD OPIEKI ZDROWOTNEJ SZPITAL UNIWERSYTECKI W KRAKOWIE;RIGAS TEHNISKA UNIVERSITATE;AZIENDA OSPEDALIERA PAPA GIOVANNI XXIII;INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE;HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH;UNIVERSITATS-HERZZENTRUM FREIBURG-BAD KROZINGEN GMBH;NEOPLAS GMBH;SERVICIO MADRILENO DE SALUD;KITOZYME SA;BIOTRONIK SE & CO. KG;STICHTING SINT ANTONIUS ZIEKENHUIS;BENEDIKT-KREUTZ REHABILITATIONSZENTRUM FUER HERZ- UND KREISLAUFKRANKE BAD KROZINGEN EV;UNIVERSITY OF LEICESTER;KATHOLIEKE UNIVERSITEIT LEUVEN";"PL;LV;IT;FR;DE;ES;BE;NL;UK";"/MED;/MBI";1;0;1;0;0;0 100627;283214;LEMSUPER;ONG;FP7-NMP;NMP.2011.2.2-6;FP7;LIGHT ELEMENT MOLECULAR SUPERCONDUCTIVITY: AN INTERDISCIPLINARY APPROACH;2011-10-01;2015-03-31;http://lemsuper.eu/;This project will develop methodology for the design of light element (B, C, O) cluster/molecule-based superconducting systems with higher transition temperatures. This will be achieved by integrating chemical synthesis of new materials with physical control of electron density and delocalisation underpinned by theoretical understanding benchmarked against evidence from advanced spectroscopies and electronic property measurements to provide a unique multidisciplinary training environment. The consortium brings together ten world-leading EU/Japan groups in chemical design/materials synthesis (Liverpool/Okayama/Mainz/Aoyama Gakuin), physical control methods at extreme pressures/high electric fields (Osaka/Tokyo), evaluation of structural and electronic properties (Durham/Ljubljana) and theory and simulation (Trieste/Tokyo). The step change in the properties of molecular superconductors and the fundamental understanding of the novel competing electronic ground states from which superconductivity will emerge will be achieved by focussing on light element materials in which a fine balance exists between electron-phonon coupling and the electron correlations recently identified as significant in these systems. The rich diversity of molecular materials classes with high frequency phonons implicated in phonon-driven mechanisms of superconductivity and the ability to systematically control the importance of co-existing electron correlations in these narrow band systems by chemical and physical means justify our choice of targets. Light elements are cheap, abundant, non-toxic and environmentally benign and thus ideal candidates for sustainable energy-saving superconductor technologies without the need to use toxic and/or rare elements. The discovery of light element molecular superconductors with figures-of-merit needed for applications is a grand challenge requiring the fundamental research proposed here to identify proof-of-concept materials and scientific understanding.;2167505,8;1606660;FP7-NMP-2011-EU-Japan;/CP-FP;UNIVERSITY OF DURHAM;UK;"JOHANNES GUTENBERG-UNIVERSITAT MAINZ;INSTITUT JOZEF STEFAN;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;SCUOLA INTERNAZIONALE SUPERIORE DI STUDI AVANZATI DI TRIESTE;THE UNIVERSITY OF LIVERPOOL";"DE;SI;IT;UK";/MAT;1;0;1;0;0;0 186998;612743;INSIGHT_E;;FP7-ENERGY;ENERGY.2013.9.2.1;FP7;Interdisciplinary Strategic Intelligence wareHouse and Think-tank for Energy;2014-02-01;2017-01-31;;"As today’s energy policy decisions are not only very complex, but also fundamentally political decisions, the necessity to build them on sound, unbiased and up-to-date information/knowledge makes energy policy analysis and advice from a broad array of non-commercial actors key to effective policy formulation. Taking this into account, it is the aim of this project to establish a multidisciplinary and independent energy think tank consisting of experts from the energy sector, top researchers, engineers, leading trade, economic, environmental, and legal experts who are experienced in delivering high quality policy advice and impact assessments. The think tank will provide policy makers at the European level with objective and unbiased policy advice as well as insights on policy options, including an assessment of their potential impact. Moreover, the think tank will bring to the attention of political decision-makers new trends in technology as well as the objectives and activities of important stakeholders that shape energy policy-making in Europe. In order to assess policy options concerning the four dimensions of sustainability (environmental, economic, social, institutional), the project will use an integrated assessment framework, backed by high-quality data resources available to the project consortium. To complement this, the project will establish innovative methods of stakeholder engagement and trend identification through the establishment of an ‘Energy Observatory’. Moreover, with transparency being of significant value, INSIGHT_E will make its models, assumptions, and scenarios available through a ‘Scenario Information System’. Implementing a flexible and at the same time profound information tool will bring about significant improvements to the policy making process and hence secure a climate-friendly energy policy. ";2217964,53;1999508,32;FP7-ENERGY-2013-2;/CSA-SA;KUNGLIGA TEKNISKA HOEGSKOLAN;SE;"STAKEHOLDER FORUM FOR A SUSTAINABLE FUTURE LBG;KIC INNOENERGY SE;ENERDATA SAS;INSTITUT FRANCAIS DES RELATIONS INTERNATIONALES;ENERGY ENGINEERING ECONOMIC ENVIRONMENT SYSTEMS MODELING AND ANALYSIS SRL;KARLSRUHER INSTITUT FUER TECHNOLOGIE;PAUL SCHERRER INSTITUT;UNIVERSITAET STUTTGART;UNIVERSITY COLLEGE LONDON;UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK;ENERGETSKI INSTITUT HRVOJE POZAR";"UK;NL;FR;IT;DE;CH;IE;HR";"/ESV;/EST";1;0;1;0;0;0 99073;267171;BRIDGE;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-COFUND;FP7;Brain & BehaviouR InterDisciplinary rEsearch;2011-01-01;2015-12-31;http://bbl.unige.ch/bridge/;"This programme aims at enabling a new generation of researchers to tackle frontiers issues about the brain and mind in a multi-disciplinary and multi-methodological fashion. Neuroscience has made many recent advances to connect mental and social phenomena with brain processes. But social sciences and humanities have also made a major progress in understanding human behaviours, and it is urgent to train fellows to better integrate knowledge and technical skills from various traditional disciplines. A rare opportunity to educate young scientists to make novel bridges between brain and behavioural sciences is offered by the creation of the Brain & Behaviour Laboratory (BBL) at UNIGE. The BBL does not only have cutting-edge research facilities (from MRI, EEG, and TMS to virtual reality and multimodal social observation labs) – but it constitutes a unique structure since it is jointly coordinated by two multi-disciplinary institutions: the Interfaculty Neuroscience Centre (CIN) regrouping neurologists, biologists, cognitive psychologists, and computational scientists; and the Interfaculty Centre for Affective Sciences (CISA) gathering psychologists, philosophers, economists, sociologists, lawyers, and art experts – who all study emotional and motivational behaviours in individual and societal contexts. These two centres have launched an innovative and dynamic collaboration in the BBL that now allows many catalytic interactions and bridges between different approaches and levels of analysis among scientists from various disciplines. BRIDGE will train incoming fellows to master the scientific approaches and techniques developed in the BBL, while it will also support outgoing fellows to acquire knowledge, skills, or data that are not currently present in the BBL, and encourage them to return afterwards with reintegrating fellowship. BRIDGE will also set up a new education program completing at a common postdoctoral level the existing doctoral schools of CIN and CISA.";5658950;2263580;FP7-PEOPLE-2010-COFUND;/MC-COFUND;UNIVERSITE DE GENEVE;CH;;;"/SOC;/COO;/NET";1;0;1;0;0;0 101662;289316;CALLISTO;ONG;FP7-KBBE;KBBE.2011.1.3-03;FP7;Companion Animals multisectoriaL interprofessionaL and Interdisciplinary Strategic Think tank On zoonoses;2012-01-01;2014-12-31;http://www.callistoproject.eu/joomla/;"Since more and increasingly different species of animals are kept as companions one has to face the fact that apart from the well documented positive effects of human-animal interaction there are negative consequences as well. CALLISTO will focus on the risks of zoonotic infectious diseases associated with companion animals. To do so, we will form a multidisciplinary, multisectorial and interprofessional network of experts representing the major relevant stakeholders. In a 3 year program we will provide an overview of the current situation with regard to the role of companion animals as a source of infectious diseases for people and food animals. We will identify knowledge and technology gaps for the most important zoonoses and will propose targeted actions to reduce the risk of zoonotic diseases transferred via companion animals. Furthermore, we will keep our stakeholders and the general public informed of our results in order to contribute to the uptake of the proposed actions and to promote risk-awareness in healthy human-animal relationships. To this purpose, CALLISTO will install a total of seven Expert Advisory Groups (EAG), consisting of experts in complementary fields of interest that will meet at regular intervals in order to exchange perspectives, knowledge and ideas and to produce expert documentation that serves as input from the specific EAG to the CALLISTO Conferences. The following EAGs will be installed: EAG User Community, EAG Policy Actions; EAG Zoonotic Viral Infections; EAG Zoonotic Bacterial Infections, EAG Zoonotic Parasitic Infections, EAG Epidemiology and underlying factors, and EAG Sociology and Welfare. The CALLISTO Synthesis Conferences are the center stage of the project, where experts from all EAGs come together to engage in discussions with each other and with other representatives from outside the network. Results from the Conferences will be widely disseminated.";1133678,6;999998;FP7-KBBE-2011-5;/CSA-SA;FEDERATION OF VETERINARIANS OF EUROPE AISBL;BE;"FEDERATION OF EUROPEAN COMPANION ANIMAL VETERINARY ASSOCIATIONS;WORLD SMALL ANIMAL VETERINARY ASSOCIATION;KOBENHAVNS UNIVERSITET;ISTITUTO ZOOPROFILATTICO SPERIMENTALE DELL'ABRUZZO E DEL MOLISE G CAPORALE;UNIVERSITY OF BRISTOL;THE HEBREW UNIVERSITY OF JERUSALEM;ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM;INTERNATIONAL ASSOCIATION OF HUMAN-ANIMAL INTERACTION ORGANIZATIONS NON PROFIT CORPORATION";"FR;CA;DK;IT;UK;IL;NL;US";/VAS;1;0;1;0;0;0 102277;283617;GENOCIDE;ONG;FP7-IDEAS-ERC;ERC-SG-SH2;FP7;Corpses of Genocide and Mass Violence: Interdisciplinary and Comparative Approaches of Dead Bodies Treatment in the 20th Century (Destruction, Identification, Reconciliation);2012-02-01;2016-01-31;;In Europe and all over the world, genocide and mass violence have been a structural feature of the 20th century. This project aims at questioning the social legacy of mass violence by studying how different societies have coped with the first consequence of mass destruction: the mass production of cadavers. What status and what value have indeed been given to corpses? What political, social or religious uses have been made of dead bodies in occupied Europe, Soviet Union, Serbia, Spain but also Rwanda, Argentina or Cambodia, both during and after the massacres? Bringing together perspectives of social anthropology, history and law, and raising the three main issues of destruction, identification and reconciliation, our project will enlighten how various social and cultural treatments of dead bodies simultaneously challenge common representations, legal practices and moral. Project outputs will therefore open and strengthen the field of genocide studies by providing proper intellectual and theoretical tools for a better understanding of mass violence’s aftermaths in today societies.;1197367;1197367;ERC-2011-StG_20101124;/ERC-SG;ECOLE DES HAUTES ETUDES EN SCIENCES SOCIALES;FR;"THE UNIVERSITY OF MANCHESTER;UNIVERSITE DE GENEVE;RIJKSUNIVERSITEIT GRONINGEN";"UK;CH;NL";/SOC;1;0;1;0;0;0 100463;249736;THINK;;FP7-ENERGY;ENERGY.2009.9.2.1;FP7;A Think Tank Hosting an Interdisciplinary Network to provide Knowledge support to EU Energy Policy Making;2010-06-01;2013-05-31;;"The three year coordinating action THINK will improve the knowledge support to policy making by the European Commission in the context of the Strategic Energy Technology Plan. THINK is organized around a multidisciplinary group of 24 experts covering five dimensions of energy policy: science and technology, market and network economics, regulation, law, and policy implementation. The Think Tank will respond to the European Commission’s evolving needs on a semester basis and produce 12 dossiers and a book. Each semester, two projects will go through the quality process of the Think Tank, including an expert hearing to test the robustness of the work, a discussion meeting inside the Think Tank, and a public consultation to test the public acceptance of different policy options by involving the broader community. Each Think Tank dossier will therefore include four chapters: 1) the Think Tank assessment of the energy policy options with clear recommendations for policy makers from the drafting team under guidance of the Project Leader, 2) a report including the comments from two Think Tank Advisors, 3) the expert hearing summary, and 4) the public consultation conclusions. The coordinating action THINK will reduce the costs related to the implementation of the ambitious EU energy policy targets by assessing the impacts of policy options using an innovative organisational and analytical frame. With a core group of about 15 nationalities, this coordinating action will also help counter the fragmentation of research in Europe and bridge the gap between Member States and the European Commission by creating a common knowledge base for decision making in energy policy. ";2464401,5;2188848,1;FP7-ENERGY-2009-2;/CSA-CA;EUROPEAN UNIVERSITY INSTITUTE;IT;"BUDAPESTI CORVINUS EGYETEM;BECKER BUTTNER HELD PARTNERSCHAFT;UNIVERSIDAD PONTIFICIA COMILLAS;UNIVERSITA COMMERCIALE LUIGI BOCCONI;ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE;TECHNISCHE UNIVERSITAET BERLIN;FONDAZIONE ENI ENRICO MATTEI;POTSDAM INSTITUT FUER KLIMAFOLGENFORSCHUNG;RICERCA SUL SISTEMA ENERGETICO - RSE SPA;UNIVERSITETET I OSLO;POLITECHNIKA LODZKA;LUNDS UNIVERSITET;DOWEL MANAGEMENT;Kuhbier sprl;FUNDACAO GOMES TEIXEIRA;KATHOLIEKE UNIVERSITEIT LEUVEN;INSTITUTE OF COMMUNICATION AND COMPUTER SYSTEMS";"HU;DE;ES;IT;CH;NO;PL;SE;FR;BE;PT;EL";"/OET;/POL";1;0;1;0;0;0 98880;269441;SIT-SG;ONG;FP7-IDEAS-ERC;ERC-AG-SH2;FP7;Security in transition: An Interdisciplinary Investigation into the Security gap;2011-06-01;2016-11-30;;"The twentieth century model of security, based on the rule of law and policing within nation-states and conventional military forces externally is no longer easily applicable to twenty first century global security risks. The security gap refers to the fact that millions of people live in situations of intolerable insecurity as a consequence of armed conflict, organised crime, terrorism, financial crisis, poverty and inequality, environmental degradation, vulnerability to natural disasters to name but some of these risks and yet current public security provision is not designed to address these sources of insecurity and, indeed, as recent wars in Iraq and Afghanistan have shown, sometimes makes them worse. Security in transition’ is about investigating and identifying the nature of the security gap and tracking the ways in which public and private agents are adapting. It has five components: narratives; indicators; rules; tools; and geographies";2391669,6;2391669,6;ERC-2010-AdG_20100407;/ERC-AG;LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE;UK;;;/SOC;1;0;1;0;0;0 91159;230368;ICTETHICS;ONG;FP7-SIS;SiS-2008-1.1.2.1;FP7;ICTethics. An Interdisciplinary Approach for Addressing Ethical, Social and Legal Aspects of ICT;2009-03-01;2013-02-28;;"'There is an urgent need for a systematic analysis of the ESLA aspects of Research in ICT, of the same type as developed by the ESLA (Ethical Social and Legal Aspects) working group on biotechnology, established by the European Commission in the early 1990s. Some ESLA-like reflection on ICT is ongoing, but is fragmented and ad hoc. It risks lagging behind technological developments that are already moving towards a 'post PC era' and the internet of things. It is necessary to think through the ethical issues before developments proceed rather than afterwards when science and industry may be constrained by regulations that deter innovation and hamper just and balanced deployments. A systematic ESLA reflection will also assist industry in reflecting upon the impacts of new developments in science and technology and what reactions they may engender amongst publics in different cultures and polities. The project will perform an integrated ESLA of identified strategic ICT developments that have the potential to revolutionize private and social life over the next five years. It will analyse (a) the development of intelligent environments, (b) the convergence of the physical, the mental and the virtual, (c) the internet of things and (d) ICT for security. It will focus on flagship developments like the personal health system, the humanoid robot assistant, RFID and biometrics identification. The results of the study will be translated into a targeted feedback to all stakeholders involved, to the public at large and to general innovation and e-Inclusion policy. This multi-actor engagement and participation strategy is key to the proposed work of the project in promoting ESLA informed dialogue on the impacts of future ICT innovations. The work will be carried out by a consortium of 4 experienced teams that have been active as participants in the process of the EC in studies in the ESLA of biomedicine who are now ready to lay the groundwork for a high level ESLA of ICT.'";1228520;942540;FP7-SCIENCE-IN-SOCIETY-2008-1;/CP;INTERNATIONAL FORUM FOR BIOPHILOSOPHY;BE;"FONDAZIONE LELIO E LISLI BASSO-ISSOCO;UNIVERSITY OF LEEDS;LANCASTER UNIVERSITY";"IT;UK";"/ETH;/SCI";1;0;1;0;0;0 89822;209044;INTELEG;ONG;FP7-IDEAS-ERC;ERC-SG-SH5;FP7;The Intellectual and Material Legacies of Late Medieval Sephardic Judaism: An Interdisciplinary Approach;2008-09-01;2012-08-31;;From the 13th to the 15th centuries, the Jews of the Iberian Peninsula (Sepharad) lived side by side with Christians and Muslims. Although persistent tensions existed between these three groups, their members also participated in a common artistic, intellectual and scientific endeavour that produced the requisite conditions for the dawn of the European Renaissance. The worldviews of all three communities revolved around their sacred texts—the Hebrew and Christian Bibles and the Qur’an. This project will take as a focal point Judaism and its sacred text, and will explore its role and impact in late medieval society at large. The project will coordinate the research of a group of young scholars doing groundbreaking work in the field, all sharing a cross-cultural and inter-disciplinary perspective. As a group, we will bring under analysis a wide range of concepts—the production of sacred texts as objects, the history of their cataloguing and preservation, the multiple and conflicting interpretations of their contents, their role as social agents that fostered coexistence or created exclusions, their impact in literature and the arts, their relationship with medieval science, and their relationship to Muslim and Christian Scriptures. The project has a special relevance for today’s multicultural and pluralistic Europe, as it can help to minimize fundamentalist readings of the sacred texts, bring about a greater understanding of the historical roots of modern intercultural conflict and, ultimately, contribute to the development of non essentialist theories of race and culture.;719336;719336;ERC-2007-StG;/ERC-SG;AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS;ES;;;/SOC;1;0;1;0;0;0 106890;320375;PantaRhei;ONG;FP7-IDEAS-ERC;ERC-AG-PE10;FP7;Interdisciplinary Integrated Forecasting System for Fluid Flows;2013-03-01;2018-02-28;;A high performance modelling system is proposed for simulating multi-scale flows with an unprecedented range of multidisciplinary physical applications. Computer simulations of global weather at horizontal resolutions in the order of a kilometre (i.e. nonhydrostatic) will become operational for numerical weather prediction (NWP) beyond 2020. Existing NWP models operate at hydrostatic scales and are not equipped to resolve convective motions where nonhydrostatic effects dominate, thus impairing the fidelity of forecasts. While NWP strives to extend the skill towards finer scales, nonhydrostatic research models endeavour to extend their realm towards the global domain. The two routes of development must cross, but the approach how to merge the diverse expertise is far from obvious. The proposed work will synthesise the complementary skills of two exceptionally successful modelling systems: ECMWF's Integrated Forecasting System (IFS) and the nonhydrostatic research model EULAG formulated by the principal investigator. The IFS is one of the most comprehensive Earth-system models available in the world, while EULAG offers unprecedented expertise in multidisciplinary computational fluid dynamics (CFD) ranging from simulations of laboratory flows to magneto-hydrodynamics of solar convection. The essence of the proposal is a pioneering numerical approach, where a nonhydrostatic global model is conditioned by global hydrostatic solutions within a single code framework. The key technology are EULAG's numerical procedures expressed in time-dependent generalized curvilinear coordinates, pairing the mathematical apparatus of general relativity with modern CFD. The new model will predict with greater fidelity extreme weather events that are critical to the protection of society while sustaining Europe’s role as the world leader in operational NWP. Moreover, this model will be one of the most advanced computing tools available to the European community for research and education.;999559;999559;ERC-2012-ADG_20120216;/ERC-AG;EUROPEAN CENTRE FOR MEDIUM-RANGE WEATHER FORECASTS;UK;;;"/PSE;/ENV;/EAR";1;0;1;0;0;0 93048;240009;IOWAGA;ONG;FP7-IDEAS-ERC;ERC-SG-PE10;FP7;Interdisciplinary Ocean Wave for Geophysical and other applications;2010-01-01;2013-12-31;;"Ocean waves are the essential gearbox between the atmosphere and ocean and also consitute a very peculiar prism through which most satellite sensors see the ocean. IOWAGA proposes a systemic investigation of ocean waves for improving the ocean surface wave compartment of Earth system models. The project will integrate in a coherent manner exisiting and new wave-related observations from multiple sources, including remote sensing, seismic records, and in situ measurements, from climate and global scales to coastal scales and single events. Going through several cycles from observations to numerical modelling via theory and parameterizations, a consistent numerical model will be refined. This modelling tool will be exploited for multi-scale hindcasts and analyses of wave related parameters, with applications to geophysics at large, in particular remote sensing, air-sea interactions, coastal hydrodynamics and seismic studies, and practical applications with associated societal benefits (ocean energy planning and management, marine safety, pollution mitigation &). The consistency between the various wave observations and the numerical modelling efforts is essential to constrain and advance better understandings of wave-related processes, to improve the accuracy of the wave-related parameters to be estimated, but also to help instrumental designs and future ocean surface remote sensing space observations. IOWAGA will be a focal point for ocean wave research, with close connection to other efforts in Europe that are focused on other compartments of the Earth system models.";1099040;1099040;ERC-2009-StG;/ERC-SG;INSTITUT FRANCAIS DE RECHERCHE POUR L'EXPLOITATION DE LA MER;FR;;;"/PSE;/ENV;/EAR";1;0;1;0;0;0 100822;285837;STRONGER;ONG;FP7-REGPOT;REGPOT-2011-1;FP7;Strengthening transdisciplinary research on infectious and emerging diseases in French Guiana: linking fieldwork, benchside and bedside;2011-11-01;2015-04-30;;"French Guiana is the sole European Union (EU) outermost region located in the Amazonian forest complex of South America. Its human population has to frequently face epidemics of diverse origins (viral, parasitic or bacterial). The emergence of infectious agents is determined by socioeconomic, environmental and ecological factors. Infectious cycles, particularly for vectors or animal pathogen reservoirs may be affected by the anthropisation of the forests or behavioural changes of local populations. These conditions, in turn, expose human beings to wild cycles and favour the breakdown of species barriers. The study of health risks at the interface between the forest and human beings is a challenge undertaken by STRonGer consortium. The main objective of the project is to set-up a taskforce that is more capable of managing infectious and emerging diseases in French Guiana. As coordination and support actions, STRonGEr will create a favourable context allowing the beneficiaries in French Guiana to be in the position to carry out research with the following strategic objectives: - promoting a close cooperation and twinning actions for upgrading and boosting human potential in sciences and technologies, - reinforcing diagnostic and management capacities by updating the available equipment and introducing new technologies, - increasing the research capacities through highly qualified human resources and technical equipment, - holding seminars and a scientific conference involving international experts to raise the local human capacities, - disseminating the acquired expertise through different supports. Successful achievement of STRonGer’s aims is expected to promote scientific excellence and enhance visibility of the consortium members in research on infectious and emerging diseases. Finally, the impact of upgrading the research potential on this topic will be enormous in terms of public health not only for French Guiana but also for the Guyana Shield and beyond.";4173771,6;3726156;FP7-REGPOT-2011-1;/CSA-SA;INSTITUT PASTEUR;FR;;;/REG;0;1;0;0;1;0 90988;230381;TECHNOLIFE;ONG;FP7-SIS;SiS-2008-1.1.2.1;FP7;a Transdisciplinary approach to the Emerging CHallenges of NOvel technologies: Lifeworld and Imaginaries in Foresight and Ethics;2009-03-01;2011-11-30;;"The TECHNOLIFE project will approach the SiS 5.1.1.2 call by developing new ethical frameworks to address ethical concerns of Europeans in relation to three technological fields: ICTs, Geographical Imaging Systems and converging technologies to enhance the human body. It will supply valuable insights on how issues of ethical concern to groups, publics and citizens can be considered in EC policy in the three technological fields. We propose a novel approach to the research on ethical frameworks, using the concept of imagined communities as a way of getting to ethical concerns in ways that do not unduly suppress their complexity, heterogeneity and communicatively challenging character. The emphasis on information, communication and perception enhancing technologies is appropriate since these are strong promoters in the ongoing restructuring of social groups and imaginaries that go to make up the future Europe. They also transform the very meaning of human sociability, identity, communication and community in ways that pose great challenges to ethical theory and ethics for policy. Dominant imaginaries, ethical concerns and broad technological developments will be described deploying insights from a number of disciplines. These will be fed into an online database where they will be used for deliberation by a number of invited participants from concerned groups and publics. The results of the process will be analysed and interpreted to identify central imaginaries and their related arguments and viewpoints among the relevant groups. The qualitative data will then be used to: 1) develop new ethical frameworks fitted to the social and analytic level of imagined communities; 2) provide guidelines for the EC on policy in the three technological fields; 3) establish a web portal that can be used for further deliberation on the three fields, and 4) supply documentation on the overall process to be used for the development of ethical frameworks in other technological fields.";1049041,6;809343;FP7-SCIENCE-IN-SOCIETY-2008-1;/CP;UNIVERSITETET I BERGEN;NO;"TARTU ULIKOOL;THE UNIVERSITY OF MANCHESTER;KOBENHAVNS UNIVERSITET;LANCASTER UNIVERSITY;UNIVERSITAT AUTONOMA DE BARCELONA;CARDIFF UNIVERSITY;UNIVERSITE DE VERSAILLES SAINT-QUENTIN-EN-YVELINES.;JRC -JOINT RESEARCH CENTRE- EUROPEAN COMMISSION";"EE;UK;DK;ES;FR;BE";"/ETH;/SCI";0;1;0;0;1;0 109500;607492;MERMAID;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-ITN;FP7;Microbial Resource Management and Engineering in the Urban Water Cycle;2013-09-01;2017-08-31;;"We will provide the first-ever research training in the transdisciplinary area of Microbial Resource Management and Engineering (MRME) to develop new concepts and technologies to meet the imminent societal challenge of closing the Urban Water Cycle (UWC), the sustainable management of residual waters and the preparation and distribution of safe potable water. The network consists of 10 regional world-leading Network Partners (NP) from private and academic sectors in DK, BE, UK, PT, CH, SE, complemented by 8 associated partners. Transdisciplinary training of 13 ESR and one ER will span from (molecular) microbial ecology to environmental engineering. Each ESR develops a personal and professional development plan. Training elements include expert training through cutting-edge individualized research projects, cross-sectoral mentorships, private sector internships, and participation in Network-wide PhD schools. Schools alternate between professional and technical training. The ITN ends with a fellow-led international research symposium. A supervisory board tracks project implementation. The private sector is engaged at the highest level: 4 private partners are full NPs. The ITN will provide ESRs with transsectoral training and experience, and instill an aptitude for research valorization, to create opportunity for research careers in public and private sectors. This ITN is timely, significant, and unique, as scientific and technological advances create tremendous opportunities for MRME, training in this transdisciplinary area is essentially absent across EU, and the need for innovation in closing the UWC is pressing, as water resources dwindle, urban consumption grows, and existing infrastructure ages. The ITN will structure the European research area and strengthen ties between and within the academic and private partners across regions. Researchers will be trained at the highest level with job prospects across academic, private, and public sectors.";4062590,63;4062590,63;FP7-PEOPLE-2013-ITN;/MC-ITN;DANMARKS TEKNISKE UNIVERSITET;DK;"AVECOM;UNIVERSITEIT GENT;UNIVERSITY OF NEWCASTLE UPON TYNE;UNIVERSIDADE NOVA DE LISBOA;EIDGENOESSISCHE ANSTALT FUER WASSERVERSORGUNG ABWASSERREINIGUNG UND GEWAESSERSCHUTZ;FACULDADE DE CIENCIAS E TECNOLOGIADA UNIVERSIDADE NOVA DE LISBOA;VEOLIA WATER TECHNOLOGIES AB;INSTITUTO DE BIOLOGIA EXPERIMENTAL E TECNOLOGICA";"BE;UK;PT;CH;SE";/LIF;0;1;0;0;0;3 188221;625863;NICOSS;CAN;FP7-PEOPLE;FP7-PEOPLE-2013-IEF;FP7;Niche Construction and Subsistence Shifts: Modelling coevolutionary dynamics between hunter-gatherers and vegetation communities;2014-12-15;2016-12-14;;This project seeks to explore, model, and understand the generative process behind radical cultural transitions in human societies. It will address the question of how mechanisms of cultural transmission are structured prior to major shifts in cultural systems and how this is driven by the feedback process of niche construction. Ultimately it will seek to identify conditions and variables that promote different type of equilibria, including episodes of cultural reversions, where a system returns to previously adopted set of behaviours, and instances where two or more systems coexists in the same geographic area. These questions are part of a transdisciplinary research agenda that aims to understand how culture, defined as transmittable information capable to modify the behaviour of individuals, relates to human biology and the environment. The project will have a broad spectrum of interest, but the focus will be on the ecological feedback between human and plant communities. The objectives of this project will be achieved by generating several computer simulation models that will formalise existing biological and anthropological theories. The output will serve as an heuristic device to explore the implications of the niche construction process, and to test specific hypothesis suggested by the archaeological data from prehistoric hunter-gatherers in Gujarat (India) and Tohoku (Japan). The research will be conducted within the framework of a transdisciplinary project (SimulPast), which is investigating some of the themes proposed here through an active collaboration between archaeologists, anthropologists, computer scientists, and physicists.;166336,2;166336,2;FP7-PEOPLE-2013-IEF;/MC-IEF;UNIVERSIDAD POMPEU FABRA;ES;;;;0;1;0;0;0;2 102545;295620;LOOKINGATWORDS;ONG;FP7-IDEAS-ERC;ERC-AG-SH5;FP7;Looking at Words Through Images. Some Case Studies for a Visual History of Italian Literature;2012-06-01;2017-05-31;;"'Writing a literary history (or a chapter of it) from the point of view of images represents an attempt both innovative and ambitious. The project aims at bringing a theoretical and practical contribution to a vast transdisciplinary discussion concerning: 1) forms and functions of the word/image relation in Renaissance visual and literary culture; 2) the status of Ariosto’s Orlando furioso as a canonized model (in literary, figurative and editorial field); 3) intersection between humanistic culture and new information technologies. Within the framework of a ‘visual history’ of the Italian Classics, Furioso appears as a crucial episode: in the long run, it established a successful editorial format for the 16th-century narrative poems; it turned out to be very fortunate in a broad European context and it influenced other literary and figurative traditions. The project is aimed at interpreting Furioso as a core of a huge cultural galaxy, exemplary to those who intend to interpret the literature as a transdisciplinary experience. The main goal is the building up of a digital archive which will collect: a) the most important 16th-century illustrated editions of Furioso; b) the illustrated editions of predecessors, followers and imitators of the poem, together with translations in volgare of the Classics and romance rewritings in verse. Thanks to a synoptic presentation of the iconographic corpora present in the analysed editions, it will be possible to compare the various ways in which the illustrators read and understand its text and contribute to guide its reading by the public. Such documents will be collected and made researchable in complex cross-research options that will be available in a digital archive meant to explore the Furioso’s canonizing function, from the point of view of images and printing format. This new outlook will help to redefine the text-oriented approach, bringing a better understanding of the ways through which such canonization occurs.'";1376200;1376200;ERC-2011-ADG_20110406;/ERC-AG;SCUOLA NORMALE SUPERIORE;IT;;;/SOC;0;1;0;0;0;2 97395;269961;INBIOSA;CLO;FP7-ICT;ICT-2009.8.10;FP7;INtegral BIOmathics Support Action;2011-01-01;2011-12-31;;"Research roadmaps in computational systems biology, autonomic computing and communications target the enrichment of knowledge and technology transfer between (analytic) life sciences and (synthetic) engineering sciences. However, we claim that it is impossible to make significant progress in this transdisciplinary field without a breakthrough paradigm change towards biologically driven mathematics and computation. Turing Machines used in biology and elsewhere in science today are Newtonian in a broad sense because they deal exclusively with syntax and inference rules based on discrete logic in absolute space and time to deliver predictable behaviour. Despite this approach being extraordinarily useful in engineering human processes, the interactions within the real world has proven to be vague and relational in many ways. A profoundly new understanding of the role of biology in natural and engineering sciences needs to be set out. Our driving argument is that living systems have fundamentally different notions of self-organization from those in engineering sciences. We therefore propose a research programme to investigate the imperatives of computation in a cardinal new way by comprehending the fundamental principles of emergence, development and evolution in biology. The goal will be a set of novel mathematical formalisms capable of addressing the multiple facets of an integral model and a general theory of biocomputation within an adequate frame of relevance. Its base will be a long-term fundamental research programme in mathematics, systems biology and computation that we call Integral Biomathics. The proposed support action has the goal of identifying, consolidating and organizing transdisciplinary research in Europe around this focus with the objectives: i) to devise a set of challenges for future FET research at proactive initiative level; ii) to produce a position paper motivating the need for action and reflecting the impact on science, technology & society.";165334;150000;FP7-ICT-2009-6;/CSA;SIMEONOV PLAMEN L;DE;THE UNIVERSITY OF STIRLING;UK;"/EVA;/INF;/COO;/ITT";0;1;0;0;0;2 101017;289672;COHAB;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-ITN;FP7;Diasporic Constructions of Home and Belonging;2011-11-01;2015-10-31;http://www.itn-cohab.eu/;All over the world, stable concepts of home and belonging have, for a variety of reasons, become the exception rather than the rule. This has led to dramatic cultural, social and political changes and challenges. The study of diaspora and migration has therefore evolved into a burgeoning field of research with an urgent practical relevance. In a wide and sometimes confusing array of approaches it is mainly covered by the humanities and the social sciences. The CoHaB Network unites world-leading institutions in this field in the conviction that interdisciplinary training as well as international and inter-sectoral co-operation are key to any productive study of diasporas. CoHaB gains scope and momentum by its ‘Network of Networks’ rationale, binding together already existing cooperations. It is based on the resolve to strengthen interdisciplinary research in the field with a view to establishing diaspora studies as a transdisciplinary research area in its own right. Training young researchers on the basis of this conviction means to provide them with the opportunity to conduct their work in a variety of disciplinary environments as well as outside a purely academic context. Specifically, CoHaB aims at stimulating and facilitating cooperation by negotiating core concepts between the various disciplines involved among the partner institutions. Each of these disciplines has developed its own, highly sophisticated understanding of diaspora studies, and it is high time that these diverse understandings entered into a sustained dialogue. For this purpose, early stage researchers from various disciplinary backgrounds, but with similar interests in the field of diaspora studies, will join forces to develop their projects on a shared platform. This will assist them in opening their projects to a strong, interdisciplinary research environment and in producing tangible results for their own research careers, for the scientific community, and for the general public at large.;3354340;3354340;FP7-PEOPLE-2011-ITN;/MC-ITN;WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER;DE;"SCHOOL OF ORIENTAL AND AFRICAN STUDIES, UNIVERSITY OF LONDON;THE UNIVERSITY OF NORTHAMPTON HIGHER EDUCATION CORPORATION;University of Mumbai;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;STOCKHOLMS UNIVERSITET";"UK;IN;SE";"/LIF;/SCI";1;1;0;3;0;1 87015;224017;ICT-ENSURE;CLO;FP7-ICT;ICT-2007.6.3;FP7;European ICT Environmental Sustainability Research;2008-05-01;2010-04-30;;The internationally organized scientific community 'Environmental Informatics' proposes a support action. The super ordinate goal is to promote and extend the European exchange of knowledge and information on environmental issues for a sustainable environmental development based on a well-established network. The overall idea of the Support Action includes the following activities
·\tTo identify relevant application areas for 'ICT for a sustainable development
·\tTo expand the existing network with experts from EU27\
·\tTo organise two enlarged EnviroInfo conferences
2008: 'Environmental Informatics and Industrial Ecology' and
2009: 'Environmental Management Information Systems: Accessing and Providing valuable Information for companies' sustainable oriented Decision Making' (tentative)
·\tbuild a database on research literature - based on EnviroInfo proceedings
·\tprovide a Web based information system on European environmental sustainability research
·\tto define requirements for a portal concept for the development of a 'Single information space in Europe'
and finalize with recommendation and a roadmap for inter-/transdisciplinary research to strengthen the EUROPEAN RESEARCH AREA in the field of ICT for environmental sustainability.
The group 'Environmental Informatics' provides in this Support Action long-standing experience in ICT application for communication, technology and environmental protection. While gaining additional information from other countries, an added value emerges from a growing network of experts and practitioner in research, industry, SME's and administration linked with an in-deep interdisciplinary knowledge transfer.
It is certain, that after this Support Action the current independent group will cross over again into an enlarged self-sufficient European network with a well-founded information basis.;1394026;1249994;FP7-ICT-2007-2;/CSA;TECHNISCHE UNIVERSITAET GRAZ;AT;"FORSCHUNGSZENTRUM KARLSRUHE GMBH;INTERNATIONALE GESELLSCHAFT FUER UMWELTSCHUTZ;KARLSRUHER INSTITUT FUER TECHNOLOGIE";"DE;AT";"/ELM;/ENV;/IPS;/TEL;/ESV";1;1;0;1;0;1 92253;240842;TEXTILE;ONG;FP7-IDEAS-ERC;ERC-SG-SH5;FP7;An Iconology of the Textile in Art and Architecture;2009-09-01;2013-08-31;;The fabrication of textiles is one of the oldest cultural technologies. The objective of the proposed interdisciplinary research project is to investigate the historical meanings and functions of the textile medium in art and architecture from the Middle Ages to the present. The exploration of this specific art medium should result in a historical theory or iconology of the textile. The project focussed on the textile discourse engages in a new, complex, and challenging field of research situated between art and architectural history and within cultural and visual studies, involving also other disciplines such as literary studies and social history. Moreover, it aims at connecting the two scientific cultures of the universities and museums, and it draws transdisciplinary expertise from contemporary art. The framework of the project can be described by seven interconnected subject areas which are dedicated to specific questions and which share categories of objects such as figurative tapestries, installation art, literary texts, or architectural materials. This requires a variety of instrumental methods ranging from gender studies to textual analysis, from iconography to anthropological approaches. Two postdoctoral researchers and one doctoral candidate will work on a topic related to one or more of the subject areas. The team s aim is to perform basic research in an innovative and contemporary field, independently of traditional institutional constraints, in order to contribute to the establishment of the history of textile art as an academic discipline and to the advancement of art and architectural history towards a general history of images, media, and artefacts.;686000;686000;ERC-2009-StG;/ERC-SG;UNIVERSITAT ZURICH;CH;;;/SOC;1;1;0;1;0;1 90739;237487;YOUNG PEOPLE COMM;ONG;FP7-PEOPLE;FP7-PEOPLE-IIF-2008;FP7;Communication strategies in groups of young people and their interaction with schools;2009-05-15;2010-05-14;;"The aim of this project with the Department of Education Sciences, at Universit? degli Studi Roma 3, is to identify the communication strategies by which low-income young people in urban peripheral areas make their relationship with school. Conceptual tools and research methodologies will come from a transdisciplinary approach making use of multimodal communication studies and of knowledge and expertise coming from Latin-American popular education studies, young&adult education and the researcher’s field-work and activism with children and teens living in the streets in Brazil. The relevance of this research, both for the European and the Latin-American context is linked to contemporary social processes in which groups of young people, coming from different social and cultural backgrounds, enter into the school system in a context of strong social inequalities and while the role of school education as a major training and learning place and a factor for social mobility seems to be diminished. The goal of such cooperation is, on the one side, to build up strong expertise in the field of communication phenomena, to develop abilities in analyzing communicative events, as well as use such abilities to create innovative methodologies and techniques to work with groups of young people in diverse urban contexts. On the other side, we pretend to transfer knowledge and expertise in field-work with people or groups suffering the new forms of socio-economic marginalization, especially children, teenagers and poor young people living in urban areas. The results of such researches may represent an important tool or aid for policy-making, educational policies and new pedagogic theoretical models, more appropriated to the contemporary, complex social context in which teenagers live. The goal is also to build an interdisciplinary group investigating the forms of communication used by young people coming from areas characterized by multiculturalism and social exclusion.";114054,01;114054,01;FP7-PEOPLE-IIF-2008;/MC-IIF;UNIVERSITA DEGLI STUDI ROMA TRE;IT;;;"/SCI;/EMP";1;1;0;1;0;1 89505;217381;RUFUS;ONG;FP7-SSH;SSH-2007-2.2-02;FP7;Rural Future Networks;2008-02-01;2011-04-30;http://www.rufus-eu.de/;"As the objectives of the CAP shift from an agricultural-centred approach to wider rural development, the idea of multifunctionality of rural areas comes into play. This in turn brings the CAP into closer association with a wide range of sectoral policy regimes: regional policy, spatial planning, environmental management; social, energy policy, and others. Sectoral regimes interact in complex ways, and with a determining effect on the sustainable development of rural areas. RUFUS will provide policy makers and stakeholders with better theoretical and practical understandings of how CAP measures interact with other forms of public intervention in rural development; and how policy regimes can be combined to ensure more sustainable development. RUFUS will investigate how rural development policy can be targeted at the specific endogenous potential of rural regions to encourage multiple functionality which goes beyond physical landscape potentials to include social and economic activities and opportunities. An interdisciplinary methodology will build into the analysis a qualitative analysis of the social dimension and endogenous potentials, alongside economic and ecological variables. RUFUS will establish a transdisciplinary conceptual framework on policy integration and rural multifunctionality. It will create a rural typology incorporating social aspects and endogenous potentials. Scenarios of rural futures - the trajectory of policy interaction processes - will be generated. These quantitative findings will be ‘tested’ against the reality of stakeholder experiences of regional development dynamics through case studies using visualisation techniques. The relevance of the findings for other regions will be examined with the help of an expert panel. Special emphasis is given to combining findings with other research, setting them in the context of political goals and policy problems, and transposing them into practical and meaningful recommendations for action.";1836179,2;1399331;FP7-SSH-2007-1;/CP-FP;GOTTFRIED WILHELM LEIBNIZ UNIVERSITAET HANNOVER;DE;"UNIVERSITY OF EAST ANGLIA;VERENIGING VOOR CHRISTELIJK HOGER ONDERWIJS WETENSCHAPPELIJK ONDERZOEK EN PATIENTENZORG;WAGENINGEN UNIVERSITY;LUNDS UNIVERSITET;INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE;SPRINT CONSULT GBR WISSENSCHAFT POLITIKBERATUNG;TECHNISCHE UNIVERSITEIT DELFT";"UK;NL;SE;FR;DE";"/ECO;/SOC";1;1;0;1;0;1 109805;604102;HBP;ONG;FP7-ICT;ICT-2013.9.9;FP7;The Human Brain Project;2013-10-01;2017-02-28;;Understanding the human brain is one of the greatest challenges facing 21st century science. If we can rise to the challenge, we can gain profound insights into what makes us human, develop new treatments for brain diseases and build revolutionary new computing technologies. Today, for the first time, modern ICT has brought these goals within sight. The goal of the Human Brain Project, part of the FET Flagship Programme, is to translate this vision into reality, using ICT as a catalyst for a global collaborative effort to understand the human brain and its diseases and ultimately to emulate its computational capabilities. The Human Brain Project will last ten years and will consist of a ramp-up phase (from month 1 to month 36) and subsequent operational phases.This Grant Agreement covers the ramp-up phase. During this phase the strategic goals of the project will be to design, develop and deploy the first versions of six ICT platforms dedicated to Neuroinformatics, Brain Simulation, High Performance Computing, Medical Informatics, Neuromorphic Computing and Neurorobotics, and create a user community of research groups from within and outside the HBP, set up a European Institute for Theoretical Neuroscience, complete a set of pilot projects providing a first demonstration of the scientific value of the platforms and the Institute, develop the scientific and technological capabilities required by future versions of the platforms, implement a policy of Responsible Innovation, and a programme of transdisciplinary education, and develop a framework for collaboration that links the partners under strong scientific leadership and professional project management, providing a coherent European approach and ensuring effective alignment of regional, national and European research and programmes. The project work plan is organized in the form of thirteen subprojects, each dedicated to a specific area of activity.A significant part of the budget will be used for competitive calls to complement the collective skills of the Consortium with additional expertise.;72522840;54000000;FP7-ICT-2013-FET-F;/CPCSA;ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE;CH;"ACADEMISCH ZIEKENHUIS LEIDEN;Institute of Science and Technology Austria;UNIVERSIDAD POMPEU FABRA;INSTITUT NATIONAL DE RECHERCHE ENINFORMATIQUE ET AUTOMATIQUE;LINNEUNIVERSITETET;UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6;HEINRICH-HEINE-UNIVERSITAET DUESSELDORF;EDEX - EDUCATIONAL EXCELLENCE CORPORATION LIMITED;HELSINGIN YLIOPISTO;THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;TECHNISCHE UNIVERSITAET GRAZ;INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE;UNIVERSITY OF HAIFA;UNIVERSITE LYON 1 CLAUDE BERNARD;KUNGLIGA TEKNISKA HOEGSKOLAN;THE UNIVERSITY OF MANCHESTER;FZI FORSCHUNGSZENTRUM INFORMATIK;STICHTING VU;FORSCHUNGSZENTRUM JULICH GMBH;RIKEN THE INSTITUTE OF PHYSICAL AND CHEMICAL RESEARCH;STICHTING CENTRUM VOOR WISKUNDE EN INFORMATICA;KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW;INSTITUT JOZEF STEFAN;WEIZMANN INSTITUTE OF SCIENCE;UNIVERSITEIT GENT;Bloomfield Science Museum Jerusalem (BSMJ);ETHNIKO KAI KAPODISTRIAKO PANEPISTIMIO ATHINON;Synome Ltd;UNIVERSITAT BASEL;STICHTING KATHOLIEKE UNIVERSITEIT;RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN;TTY-SAATIO;FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.;TECHNISCHE UNIVERSITAET MUENCHEN;COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES;UNIVERSIDAD DE GRANADA;SAP SE;RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG;UNIVERSITAET BERN;GERMAN RESEARCH SCHOOL FOR SIMULATION SCIENCES GMBH;SIB INSTITUT SUISSE DE BIOINFORMATIQUE;UPPSALA UNIVERSITET;UNIVERSITE VICTOR SEGALEN BORDEAUX II;UNIVERSITEIT MAASTRICHT;HITS GGMBH;INSTITUT DU CERVEAU ET DE LA MOELLE EPINIERE;PROVINCIA LOMBARDO VENETA - ORDINEOSPEDALIERO DI SAN GIOVANNI DI DIO- FATEBENEFRATELLI;AALTO KORKEAKOULUSAATIO SR;DE MONTFORT UNIVERSITY;FORTISS GMBH;UNIVERSITY OF LEEDS;ERNST STRUNGMANN INSTITUTE GGMBH;CENTRE HOSPITALIER UNIVERSITAIRE VAUDOIS;SCUOLA SUPERIORE DI STUDI UNIVERSITARI E DI PERFEZIONAMENTO SANT'ANNA;AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS;SABANCI UNIVERSITESI;INSTITUTE OF EXPERIMENTAL MEDICINE - HUNGARIAN ACADEMY OF SCIENCES;THE FOUNDATION FOR MEDICAL RESEARCH INFRASTRUCTURAL DEVELOPMENT AND HEALTH SERVICES NEXT TO THE MEDICAL CENTER TEL AVIV;THE UNIVERSITY OF SUSSEX;ECOLE NORMALE SUPERIEURE;NORGES MILJO-OG BIOVITENSKAPLIGE UNIVERSITET;SCUOLA NORMALE SUPERIORE;MEDIZINISCHE UNIVERSITAT INNSBRUCK;UMEA UNIVERSITET;UNIVERSITAT ZURICH;CONSIGLIO NAZIONALE DELLE RICERCHE;KARLSRUHER INSTITUT FUER TECHNOLOGIE;UNIVERSITE DE BORDEAUX;LES HOPITAUX UNIVERSITAIRES DE GENEVE;UNIVERSITA DEGLI STUDI DI PAVIA;BERGISCHE UNIVERSITAET WUPPERTAL;UNIVERSITE JOSEPH FOURIER GRENOBLE 1;INSTITUT PASTEUR;UNIVERSITAT DE BARCELONA;EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH;JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN;TEL AVIV UNIVERSITY;UNIVERSITAETSKLINIKUM HAMBURG-EPPENDORF;UNIVERSITETET I OSLO;POLITECNICO DI TORINO;THE UNIVERSITY OF TENNESSEE;UNIVERSIDAD DE CASTILLA - LA MANCHA;UNIVERSITE GRENOBLE ALPES;THE REGENTS OF THE UNIVERSITY OF CALIFORNIA;KAROLINSKA INSTITUTET;FONDEN TEKNOLOGIRADET;SYNAPTOLOGICS BV;WENZHOU MEDICAL COLLEGE;THE HEBREW UNIVERSITY OF JERUSALEM;UNIVERSIDAD REY JUAN CARLOS;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;ATHENS UNIVERSITY OF ECONOMICS AND BUSINESS - RESEARCH CENTER;UNIVERSITE D'AIX MARSEILLE;YALE UNIVERSITY;EBERHARD KARLS UNIVERSITAET TUEBINGEN;UNIVERSIDAD AUTONOMA DE MADRID;UNIVERSITY COLLEGE LONDON;OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL CORPORATION GAKO HOJIN;FONDAZIONE EUROPEAN BRAIN RESEARCHINSTITUTE RITA LEVI;CINECA CONSORZIO INTERUNIVERSITARIO;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;KATHOLIEKE UNIVERSITEIT LEUVEN;UNIVERSITAET BIELEFELD;UNIVERSITY OF SURREY;ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING MCGILL UNIVERSITY;MIDDLESEX UNIVERSITY HIGHER EDUCATION CORPORATION;UNIVERSIDAD POLITECNICA DE MADRID;THE UNIVERSITY OF EDINBURGH;POLYTECHNEIO KRITIS;UNIVERSITY OF SOUTHERN CALIFORNIA;LABORATORIO EUROPEO DI SPETTROSCOPIE NON LINEARI;FUNDACAO D. ANNA SOMMER CHAMPALIMAUD E DR. CARLOS MONTEZ CHAMPALIMAUD;BARCELONA SUPERCOMPUTING CENTER - CENTRO NACIONAL DE SUPERCOMPUTACION;UNIVERSITEIT VAN AMSTERDAM;KING'S COLLEGE LONDON;TECHNISCHE UNIVERSITAET DRESDEN";"NL;AT;ES;FR;SE;DE;CY;FI;UK;IL;JP;SI;BE;EL;CH;IT;TR;HU;NO;US;DK;CN;CA;PT";/INF;0;1;0;0;0;1 104328;311778;GLAMUR;ONG;FP7-KBBE;KBBE.2012.2.5-03;FP7;Global and Local food chain Assessment: a MUltidimensional performance-based approach;2013-02-01;2016-01-31;http://glamur.eu/;"General objective of the project is to integrate advancement in scientific knowledge about the impact of food chains with application of knowledge to practice to increase food chains sustainability through public policies and private strategies. This general objective will be pursued through the following specific objectives: • To develop and validate a ‘performance criteria matrix’ for assessment and comparison of food chains operating at a range of geographical scales through analysis of how food chain impacts are communicated in different spheres of society. • To build a database of quantifiable indicators of impact and a set of 20 case studies aimed at understanding how impacts are generated within specific food chains. • To advance knowledge on methodological problems and trade-offs arising when measuring and comparing the impact of food chains within and between sectors. • To assess how performance is perceived by stakeholders in different national contexts through participatory assessment and multicriteria analysis of the different typologies of food chains. • To assess the actual and potential role of public and private policies addressing food chains and to turn assessment into policy recommendations. • To build a network that turns the advancement of scientific knowledge into decision making tools for domestic and public consumers, producers, citizens, scientists, policy makers, civil society organizations. The project will be developed around the following assumptions: • Costs and benefits analysis needs methodological update: for this reason the broader concept of performance is used • The performance of food chains has multiple dimensions (economic, social, environmental, health, ethical) • To turn knowledge into practice a demand-driven approach is necessary, focusing on how food choice affects the five dimensions of impact The complexity of impacts of food chains requires plurality of methods and transdisciplinarity";3696100,35;2932328;FP7-KBBE-2012-6-singlestage;/CP-FP;WAGENINGEN UNIVERSITY;NL;"UNIVERSITY OF GLOUCESTERSHIRE LBG;EKONOMSKI FAKULTET, UNIVERZITET U BEOGRADU;International Institute for Environment and Development;FONDAZIONE ITALIANA PER LA RICERCAIN AGRICOLTURA BIOLOGICA E BIODINAMICA;CITY UNIVERSITY OF LONDON;UNIVERSITY OF THE WEST OF ENGLAND, BRISTOL;FORSCHUNGSINSTITUT FUR BIOLOGISCHEN LANDBAU STIFTUNG;NODIBINAJUMS BALTIC STUDIES CENTRE;UNIVERSITAT AUTONOMA DE BARCELONA;INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE;KATHOLIEKE UNIVERSITEIT LEUVEN;CENTRO RICERCHE PRODUZIONI ANIMALI - C.R.P.A. S.P.A.;CLM ONDERZOEK EN ADVIES BV;AALBORG UNIVERSITET";"UK;RS;IT;CH;LV;ES;FR;BE;NL;DK";/SCI;0;1;0;0;0;1 97067;261247;WALK AGAIN;ONG;FP7-IDEAS-ERC;ERC-SG-LS5;FP7;Multi-pronged Strategies to Regain Voluntary Motor Functions after Spinal Cord Injury;2010-12-01;2015-11-30;;"Severe spinal cord injury (SCI) permanently abolishes motor functions caudal to the lesion. Various strategies have been pursued to promote functional recovery after such injuries. However, none of these attempts were able to return voluntary movements in paralyzed subjects. Here, we propose an innovative transdisciplinary research program including parallel approaches that will converge into an integrated multi-pronged therapy able to restore voluntary movements after paralyzing SCI. To achieve this goal, we will capitalize on our recent breakthroughs that demonstrate the impressive capacity of pharmacological and electrical spinal cord stimulations to promote full weight bearing walking in paralyzed rats when combined with rehabilitation. In Walk Again, we will improve high level control of spinal circuits with synergistic combinations of pharmacological agents, and with the design of multisite stimulation strategies using electrode arrays. Functional electrical stimulation of muscles will provide complementary low level tuning capacities to adjust limb motion. To allow voluntary control, we will establish a new line of research and pioneer brain-spinal interfaces by which cortical modulations will directly adjust stimulations of spinal circuits and muscles. In the final stages, we will enable neurorehabilitation with this cortico-spinal neuroprosthesis in the presence of anti-NogoA regenerative therapy. The underlying objective is to devise a fully-operative neuroprosthetic system that will enable self-driven rehabilitation in a permissive plastic environment. Walk Again will fertilize frontier research with pioneer ideas that will increase European competitiveness while paving the way toward viable clinical applications to restore function in paralyzed individuals.";1395540;1395540;ERC-2010-StG_20091118;/ERC-SG;ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE;CH;UNIVERSITAT ZURICH;CH;"/BIO;/LIF";0;1;0;0;0;1 109329;600209;IPODI;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-COFUND;FP7;International Post-Doc Initiative of the Technische Universität Berlin (IPODI);2013-07-01;2018-06-30;;The International Post-Doc Initiative of the Technische Universität Berlin (IPODI) aims to promote the career development of experienced female researchers within ERA. IPODI offers in total 21 fellowship positions which will be allocated in three internationally open selection rounds with international peer review. A 24 months employment contract including social security insurance, pension coverage, as well as travel and training allowances will be offered to the successful candidates. IPODI seeks not only to increase the number of women in higher qualification levels of science, in particular in engineering science or natural science – as the Marie Curie Programme do. Above all, its main objective is to prepare highly qualified women for leadership positions in science. Thus, the challenging demand of the European Commission in implementing sustainable gender equality in science shall be realised. On the basis of scientific excellence and innovation – reflected by the excellent research environment of TU Berlin - the fellows are free to choose their own research project in one of the 7 faculties. A transparent selection process guarantees a high quality standard by international peer review. Moreover, intersectoral cooperation will be guaranteed by a close network with the private sector. Fellows will profit from these collaborations and can integrate intersectoral elements to their research career. Mentoring as a cross-generational coalition is another main element of IPODI. Therefore, a senior researcher of TU Berlin will give support as mentor. Qualified staff will ensure an open information policy by managing 3 internationally advertised calls, releasing the selection criteria and communicating the rationale behind the final decisions. IPODI will make a contribution to advancing the scientific potential of female researcher within ERA by combining intersectorality, mentoring and transdisciplinarity.;3405990;1362396;FP7-PEOPLE-2012-COFUND;/MC-COFUND;TECHNISCHE UNIVERSITAT BERLIN;DE;;;/LIF;0;1;0;0;0;1 111173;339529;RECONFORT;ONG;FP7-IDEAS-ERC;ERC-AG-SH6;FP7;Reconsidering Constitutional Formation.Constitutional Communication by Drafting, Practice and Interpretation in 18th and 19th century Europe;2014-03-01;2018-02-28;;"The genesis of the modern constitutional state in late 18th and 19th century Europe has met im-mense public awareness and cross-border participation. Though this phenomenon is well known, basic patterns of constitutional communication (i.e. socio-cultural and cross-border contexts, ‘Zeitgeist’) have never been addressed before. In this concern ReConFort applies an evolutionary, dynamic and interactive concept of forming constitutions by text, societal context, political practice, constitutional interpretation and communication. The transdisciplinary project focuses on the constitutional “discourse” around selected constituent assemblies: the Polish Sejm (1788-1792), the Spanish Cortes (1810-1812), the Belgian National Congress (1830-1831), the Frankfurt Parliament (1848-1849) and the Italian Parlamento Subalpino (1861). Albeit all these historical paradigms are particular and different, they all shared a Europe-wide public interest. The research approach draws upon mainly inedited and still unknown archival sources: cross-border correspondences, publicistic activities of protagonists, exile literature, and regional to cross-border constitutional journalism in leading public media. The synchronic comparative analysis is complemented by systematic diachronic studies. Thereby ReConFort identifies common structural criteria, features and principles in constitution forming processes. ReConFort finally aims at assessing basic determinants and mutual interdependencies of constitutional formation and communication in Europe. This research focus will estalish a deeper understanding of mutual influences of constitutional developments in Europe by pointing out the transnational dynamics of constitutional forming, practice and interpretation. Thus, ReConFort crosses the frontiers of traditional legal and historical sciences and will be of value for the present integration process of the EU.";1880373;1880373;ERC-2013-ADG;/ERC-AG;UNIVERSITAT PASSAU;DE;;;/SOC;0;1;0;0;0;1 99019;265570;WAHARA;ONG;FP7-ENVIRONMENT;ENV.2010.3.1.1-4;FP7;Water Harvesting for Rainfed Africa: investing in dryland agriculture for growth and resilience;2011-03-01;2016-02-29;http://www.wahara.eu/;"WAHARA will take a transdisciplinary approach to develop innovative, locally adapted water harvesting solutions with wider relevance for rainfed Africa. Water harvesting technologies play a key role in bringing about an urgently needed increase in agricultural productivity, and to improve food and water security in rural areas. Water harvesting technologies enhance water buffering capacity, contributing to the resilience of African drylands to climate variability and climate change, as well as to socio-economic changes such as population growth and urbanisation. To ensure the continental relevance of project results, research will concentrate on four geographically dispersed study sites in Tunisia, Burkina Faso, Ethiopia and Zambia, covering diverse socio-economic conditions and a range from arid to sub-humid climates. The project emphasizes: i) participatory technology design, i.e. selecting and adapting technologies that have synergies with existing farming systems and that are preferred by local stakeholders, yet tap from a global repertoire of innovative options; ii) sustainable impact, i.e. technologies that combine multiple uses of water, green and blue water management, and integrated water and nutrient management. Using models, water harvesting systems will be designed for maximum impact without compromising downstream water-users, contributing to sustainable regional development; iii) integration and adaptability, i.e. paying attention to the generic lessons to be learned from local experiences, and developing guidelines on how technologies can be adapted to different conditions; and iv) learning and action, i.e. a strategy will be developed to enable learning and action from successes achieved locally: a. within a region, to upscale from water harvesting technologies to water harvesting systems, and b. across regions, promoting knowledge exchange at continental scale.";2619115,27;1999312,33;FP7-AFRICA-2010;/CP-FP-SICA;STICHTING WAGENINGEN RESEARCH;NL;"METAMETA RESEARCH BV;INSTITUT DES REGIONS ARIDES;AGROTECHNOLOGY CONSULT AFRICA BV;INSTITUT DE L'ENVIRONNEMENT ET DE RECHERCHES AGRICOLES;UNIVERSITY OF LEEDS;GOLDEN VALLEY AGRICULTURAL RESEARCH TRUST;WAGENINGEN UNIVERSITY;MEKELLE UNIVERSITY";"NL;TN;BF;UK;ZM;ET";"/REG;/WAT";0;1;0;0;0;1 188626;609400;EURIAS;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-COFUND;FP7;EURIAS Fellowship Programme;2014-04-15;2019-08-14;;"The European Institutes for Advanced Study Fellowship Programme (EURIAS) was created in 2010. For the 2014-2019 period, with the support of the European Commission, the Programme could offer 212 ten-month incoming fellowships in a consortium of 16 Institutes for Advanced Study (IAS) located in 12 European countries. The Programme is open to all fields in the Humanities and Social Sciences, as well as to other disciplines. The great diversity of the academic and cultural offerings of IAS provides a unique spectrum of choice to candidates. The IAS offer research and professional opportunities that are complementary to universities and research centres. They create multi-disciplinary and multicultural learning communities, open intellectual spaces where fellows —released from their teaching and academic commitments— conduct bottom-up research with the greatest possible freedom and with the IAS support. These learning communities provide permanent intellectual stimulation as a result of the daily encounters among the fellows from a wide range of disciplines, cultures and scientific traditions. And the many activities carried out by the researchers with the support of the host IAS (in terms of work conditions, organisation of events and academic networking) further widen their intellectual, scientific and professional horizons. IAS constitute experimental spaces where, for an academic year, researchers can stray from the customary paths of their disciplines and nurture new transdisciplinary collaborations to be developed. This one-year rejuvenating professional experience gives them a fresh perspective on their research and a boost to their careers, generating long-tem impact on the fellows’ career and research back in their home institution. EURIAS contributes to structuring the IAS fellowships offer, acting as a European-wide gateway to the Institutes for Advanced Study scheme and inserting fellows into a community of scholars representing 500 researchers per year";14752783,87;5901113,55;FP7-PEOPLE-2013-COFUND;/MC-COFUND;RESEAU FRANCAIS DES INSTITUTS D'ETUDES AVANCEES;FR;;;/LIF;0;1;0;0;0;1 111213;612236;ASSET;ONG;FP7-SIS;SiS.2013.1.2-1;FP7;ACTION PLAN ON SIS RELATED ISSUES IN EPIDEMICS AND TOTAL PANDEMICS;2014-01-01;2017-12-31;;"ASSET (Action plan in Science in Society in Epidemics and Total pandemics) is a 48 month Mobilisation and Mutual Learning Action Plan (MMLAP), which aims to 1) forge a partnership with complementary perspectives, knowledge and experiences to address effectively scientific and societal challenges raised by pandemics and associated crisis management; 2) explore and map SiS-related issues in global pandemics; 3) define and test a participatory and inclusive strategy to succeed; 4) identify necessary resources to make sustainable the action after the project completion. ASSET combines public health, vaccine and epidemiological research, social and political sciences, law and ethics, gender studies, science communication and media, in order to develop an integrated, transdisciplinary, strategy, which will take place at different stages of the research cycle, combining local, regional and national levels.";4494097,17;3939880;FP7-SCIENCE-IN-SOCIETY-2013-1;/CSA-SA;ABSISKEY;FR;"ASTIKI MIKERDOSKOPIKI ETAIREIA PROLIPSIS;UNIVERSITY OF HAIFA;ZADIG SRL;ASSOCIATION LYON BIOPOLE;DATA MINING INTERNATIONAL SA;CENTRE FOR SCIENCE, SOCIETY AND CITIZENSHIP;ISTITUTO SUPERIORE DI SANITA;BMJ PUBLISHING GROUP LIMITED;ABSISKEY CP;INTERNATIONAL PREVENTION RESEARCH INSTITUT-IPRI MANAGEMENT;NATIONAL CENTER OF INFECTIOUS AND PARASITIC DISEASES;FORSVARETS FORSKNINGINSTITUTT;FONDEN TEKNOLOGIRADET;THE INTERNATIONAL EMERGENCY MANAGEMENT SOCIETY AISBL;UNIVERSITATEA DE MEDICINA SI FARMACIE'CAROL DAVILA' DIN BUCURESTI;EUROPEAN INSTITUTE OF WOMEN'S HEALTH LIMITED";"EL;IL;IT;FR;CH;UK;BG;NO;DK;BE;RO;IE";"/REG;/ITT";0;1;0;0;0;1 109356;604764;CogNovo;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-ITN;FP7;Cognitive Innovation;2013-10-01;2017-09-30;;"We aim to establish a multi-national doctoral training network in Cognitive Innovation, both as a new field of scientific investigation and a strategy for research and innovation. Cognitive Innovation adopts a transdisciplinary approach that promotes creative thinking in parallel with rigorous scientific training. In developing an educational program that stimulates creativity and finds new ways to link research with social and technological innovation, CogNovo will address important challenges identified in the EU Innovation Union initiative and produce a cohort of researchers well-equipped to contribute to the European Research Area. To demonstrate its commitment to this proposal and further enhance the impact of the CogNovo network, Plymouth University will fund an additional 12 PhD students to complement the group of EU–funded Early Career Researchers. Research within the network will be built upon an extensive multi-disciplinary base, ranging from the neuroscience of creativity, through computational modelling of cognitive processes, to investigations of group creativity, social innovation and decision making. Research training will be structured around a wide-ranging series of workshops that enrich the research experience of students beyond the confines of their specialized research topics. CogNovo students will gain advanced expertise in core disciplines and complementary skills to help them forge successful careers in academia, industry and the public sector. Students will actively shape their professional and personal development through individualized skill plans, and negotiated supervisory teams. The international network of academic and private sector partners, that forms the intellectual core of CogNovo, combines a range of expertise and resources not previously connected. Through the creation of this innovative research training program, CogNovo will produce a group of highly creative researchers who will become productive and insightful innovators.";4077315;4077315;FP7-PEOPLE-2013-ITN;/MC-ITN;UNIVERSITY OF PLYMOUTH;UK;;;/LIF;0;1;0;0;0;1 107976;312717;LeftMEXile3460;ONG;FP7-IDEAS-ERC;ERC-SG-SH6;FP7;Left-wing Exile in Mexico, 1934-1960;2013-04-01;2018-03-31;;This ERC Starting Independent Researcher Grant will support the research of one PI and two post-doctoral researchers towards a transnational and transdisciplinary history of left-wing exile in Mexico between the mid-1930s and the late 1950s. During this period, Mexico witnessed the arrival of tens of thousands of political refugees from Europe and later a smaller number of émigrés from the U.S.. Mexican authorities not only actively welcomed these communities of exile but encouraged and supported their political and cultural activities to establish Mexico as an arena for left-wing internationalism. Outside agencies, such as right-wing European governments, the Comintern, and the U.S.-American FBI and OSS/CIA were actively engaged in monitoring and influencing these communities in Mexico. The researchers will draw on new source materials from the Comintern Archives, Mexican state and university archives, and the U.S. National Archives and the Hoover Foundation alongside the rich collections of European archives to prepare studies that cut across the conventional orientation by source provenance, national perspectives, or disciplinary specialisation. The aim is to arrive at a topographical understanding of exile as a political practice manifested in meetings, lectures, political publications, and interventions in domestic Mexican and world political discourse, mechanisms of a transfer of knowledge in education policies and the transnational public sphere, cultural representations of the émigrés’ engagement with their host nation in literature, art, and architecture, in music, photography and painting, and prevailing perceptions and constructions of ethnicity and gender. The results of this research will be presented at two project workshops and one international conference. The project will generate three monographs and one edited volume with contributions from leading international scholars.;957563;957563;ERC-2012-StG_20111124;/ERC-SG;UNIVERSITAET ZU KOELN;DE;;;"/SCI;/SOC";0;1;0;0;0;1 96308;252574;UNBOUND23;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IOF;FP7;WELFARE UNBOUND. THE CASE OF URBAN POLICIES AGAINST HUMAN TRAFFICKING: FROM CHICAGO TO SICILY;2011-08-15;2013-11-14;;"The urban treatment of human trafficking as “public problem” represents an emblematic policy case to explore the controversies of the new “European spatial politics of social protection”. Cities emerge as spaces of “unbounding” by which practices of internationalization of welfare delegitimize national “law enforcement” boundaries. “Policy entrepreneurs” – governmental, intergovernmental and non-governmental organizations, faith organizations, unions, etc - working against human trafficking within the framework of “internationalization”, challenge conventional ways by which we are accostumed to think about the “public” and democracy. The comparison between two urban initiatives in USA And EU intends to highlight the times, the contents and the modalities by which coalitions of “policy entrepreneurs” integrate welfare and security policies against human trafficking and make different trade-off between standardization and innovation emerge. Relevance of the project (1) To enrich the debate on the formation of a European social solidarity model overcoming the relationship citizenship/sovereignty/territorialiy; (2) to improve policymaking and urban research. Objectives (1) to detect intersectoral effects of targeted actions on vulnerable groups and the different forms of enactment of actors and resources by which the problem is treated as “local”; (2) to define and transfer integrated knowledge frameworks on the regional effects of the internationalisation of welfare, and thereby, on the changing nature of the “public” of social policy; (c) to develop a frontier-research profile capable of encouraging innovation and regional cooperation as well as producing innovative “transdisciplinary” arrays of knowledge on “cities” and “territories”, beyond conventional approaches based on the dualism urban(place)/social (people). Research methodology Comparative case study; Ethnography, Direct Participant Observation and complementary qualitative tools";149975;149975;FP7-PEOPLE-2009-IOF;/MC-IOF;UNIVERSITA IUAV DI VENEZIA;IT;;;"/LIF;/EDU";0;1;0;0;0;1 99532;265471;EAU4FOOD;ONG;FP7-KBBE;KBBE.2010.1.2-03;FP7;European Union and African Union cooperative research to increase Food production in irrigated farming systems in Africa/ EAU4Food;2011-07-01;2015-06-30;;EAU4Food seeks to address the need for new approaches to increase food production in irrigated areas in Africa, while ensuring healthy and resilient environments. Potential pitfalls of introducing innovations in local farming systems, like limited adoption by farmers and trade-off effects to other (environmental) systems are overcome by, respectively, i) utilizing a true transdisciplinary approach, which involves the active participation of all stakeholders in all relevant disciplines, and ii) by determining and respecting so called sustainable production thresholds. EAU4Food is executed in four irrigated areas in Africa, viz. Southern Africa (Mozambique and South-Africa), Tunisia, Mali and Ethiopia to fully benefit from the potential of cross distributing promising strategies and innovations. At each site, key indicators, risk factors, farm strategies and biophysical parameters are monitored for identification of current constraints to food production and to evaluate agro-ecological and socio-economic impacts of improved practices and/or innovations after implementation. Results of EAU4Food are distilled into tailor made support tables and guidelines for different user groups. These support tables and guidelines support decision making processes at local level by overseeing short-term and long-term effects of alternative practices and improved strategies. EAU4Food is expected to have significant positive impacts on agricultural production at farm level for many years to come, and on wider policy processes at national and trans-national levels. To enlarge and maintain the impact of EAU4Food, capacity building programmes are developed at different levels, going from farmer to farmer exchange up to exchange of scientific personnel. Moreover, further exploitation of the results of EAU4Food is supported via other mediums such as ‘songs of success’, documentaries, school programmes, policy briefs, fact-books and scientific publications and presentations.;4941145,4;3994856;FP7-AFRICA-2010;/CP-IP-SICA;STICHTING WAGENINGEN RESEARCH;NL;"INSTITUT NATIONAL DE RECHERCHES EN GENIE RURAL, EAUX ET FORETS;INSTITUT D'ECONOMIE RURALE;AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS;COUNCIL FOR SCIENTIFIC AND INDUSTRIAL RESEARCH;CENTRE DE COOPERATION INTERNATIONALE EN RECHERCHE AGRONOMIQUE POUR LEDEVELOPPEMENT - C.I.R.A.D. EPIC;UNIVERSIDADE EDUARDO MONDLANE;INTERNATIONAL WATER MANAGEMENT INSTITUTE IWMI;OVERSEAS DEVELOPMENT INSTITUTE;UNIVERSITY OF ZAMBIA;MEKELLE UNIVERSITY;LISODE SARL;STELLENBOSCH UNIVERSITY";"TN;ML;ES;ZA;FR;MZ;LK;UK;ZM;ET";"/WAT;/FOO;/AGR";0;1;0;0;0;1 94631;256522;XIMENES;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-RG;FP7;Art, Natural Science, Local History, and the New World in Counter-Reformation Antwerp: The Collection of the Portuguese Merchant-Banker Manuel Ximenes (1564-1632);2010-07-01;2014-06-30;;In early modern Europe, the collections of elite individuals were important sites to produce, exchange, and display knowledge. The reference point for my study is one of the most splendid collections of early 17th-c. Antwerp, that of the Portuguese merchant-banker Manuel Ximenes (1564-1632), praised by his contemporaries for his ‘universal knowledge of the sciences’. This is the first study of a collection of a converso merchant-banker whose family was intimately involved in Antwerp’s global trade. I argue that the various sites of display in Ximenes’ palace define a courtly cosmos of science, medicine, religion, and art as well as reflect a culture of patronage, friendship, and kinship, which lay at the very center of early modern science and global trade. This is a by definition transdisciplinary project, one that takes seriously the multiple spheres of knowledge within which artful objects and art works were viewed – spheres that themselves were shaped by the emergence of the visual. It will shed new light on the interrelationships between art, science, and religion in times of religious and political change, advance our knowledge of patronage activities of wealthy foreigners, and broaden our understanding of the early modern material culture of science and art.;100000;100000;FP7-PEOPLE-2009-RG;/MC-IRG;UNIVERSITAET BERN;CH;;;/SCI;0;1;0;0;0;1 188645;613694;LATTAL;ONG;FP7-IDEAS-ERC;ERC-CG-2013-SH5;FP7;The Latin Talmud and its Influence on Christian-Jewish Polemic;2014-10-01;2018-09-30;;"'While polemics and dialogue between Judaism and Christianity are as old as the Christian religion itself, one can clearly distinguish different periods, trends and intensities in the relations between the faiths. A significant landmark in this long and complex history is the Latin translation of large sections of the Talmud, the most important Jewish post-biblical text and the basis for the development of Rabbinic Judaism. When during the 13th century Christian theologians started to examine and translate the Talmud from Hebrew and Aramaic into Latin, they were faced with a huge body of texts which represented centuries of legalistic and homiletic materials. The discovery of this immense post-biblical Jewish literature became a source of fascination for Christians who believed that this text, which encompasses every aspect of Jewish life, was fundamental both for refuting the Jewish faith and for substantiating the truth of Christianity. This realization heralded a rethinking of the place of Jews in Christian society and redefined Christian-Jewish dialogue and polemic. The purpose of our project is to edit and publish the largest extant collection of Talmudic passages translated from Hebrew into Latin, that is, the 'Extractiones de Talmud', while studying this ground-breaking document in the context of the trial and burning of the Talmud in 1240-42 and its aftermath. This project addresses vital questions of Jewish and Christian identity, still relevant to the 21st century, and can only be carried out by a transdisciplinary research team including specialists from Latin Philology, Hebrew Studies and History.'";1292700;1292700;ERC-2013-CoG;/ERC-CG;UNIVERSITAT AUTONOMA DE BARCELONA;ES;;;"/SCI;/SOC";0;1;0;0;0;1 188670;615603;SOCIOGENOME;ONG;FP7-IDEAS-ERC;ERC-CG-2013-SH3;FP7;Unravelling the genetic influences of reproductive behaviour and gene-environment interaction;2014-07-01;2019-06-30;;"'This project will be the first to engage in a comprehensive study of the role of genes and gene-environment (GxE) interaction on reproductive behaviour. Until now, social science research has focussed on socio-environmental explanations, largely neglecting the role of genes. Due to unprecedented advances in molecular genetics over the last two decades, for the first time in history we are able to examine whether there is a genetic component to reproductive outcomes, including age at first birth, number of children and infertility. Building on my substantive empirical research, I first develop a multifactor theoretical and measurement model isolating socio-environmental and lifestyle factors. Second, I apply the most cutting-edge techniques in genetics to examine the genetic architecture of reproductive behaviour, including: the first genome-wide association study (GWAS) of reproductive choice; polygenic risk scores; and, genome-wide complex trait analysis (GCTA). Third, I focus on gene-environment interactions (GxE) to test different mechanisms of how the environment moderates genetic influences. Fourth, I propose to use genetic markers as instrumental variables (IVs) in a bi-directional Mendelian randomization (MR) analysis to determine causality and address the endogeneity of lifestyle and education in reproductive outcomes. This transdisciplinary project will produce fundamentally different results, overturn established links and deliver major breakthroughs in fertility research and beyond. This project is not only ground breaking by setting a new research agenda, but due to the inclusion of new genetic variables and techniques to study the causal effects of genes and their interaction with environment, will yield major innovations useful within demography and beyond. Research builds on the proven expertise and existing collaboration with geneticists, and is carefully costed to include 2 postdocs and 2 PhDs.'";1971366;1971366;ERC-2013-CoG;/ERC-CG;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;UK;ACADEMISCH ZIEKENHUIS GRONINGEN;NL;"/REG;/ENV;/SOC";0;1;0;0;0;1 188167;629430;AIDA;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IEF;FP7;Assessments of InDividual behaviour Analysed critically;2015-09-01;2017-08-31;;Assessments of individual behaviour play important roles in research and organisations. Questionnaire scales are widely used as efficient tools for standardised assessments. But the ways in which people understand these tools and by which they generate their answers to standardised scales are still poorly understood. There is also still little description of how well people’s verbal reports actually represent observable individual behaviours and the ways in which they may reflect social beliefs and stereotypes. The AIDA project will explore how people assess and socially categorise individuals and will critically analyse the methods used for standardised assessments. It aims to unravel potential biases derived from stereotypes about gender and ethnicity, focussing on “Black” and “White” as prototypical categories of ethnicities that are at the centre of many social conflicts worldwide. A novel transdisciplinary paradigm and cutting-edge methodologies and technologies will be used to systematically deconstruct the requirements that assessment tasks impose on respondents and to reconstruct the social knowledge and the psychological processes involved therein. People’s interpretations and uses of standardised scales and social categories will be explored in the context of Online surveys and in interpersonal discussions about videotaped behaviours displayed with the same intensity by men or women of either “Black” or “White” ethnicity while the participants’ subjective views of these videos will be captured with miniature cameras. Interviewing people about their own first-person recordings activates episodic memory and enables in-depth reconstruction of psychological processes during assessment generation. These ground-breaking techniques represent major progress urgently needed to restore the match between psychological phenomena and the methods used for their investigation and will open up new horizons for evidence-based explorations of the workings of the human mind.;221606,4;221606,4;FP7-PEOPLE-2013-IEF;/MC-IEF;LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE;UK;;;;0;1;0;0;0;1 187700;622645;OASIG;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IEF;FP7;Ordered Algebraic Structures in Game Theory;2014-11-01;2016-10-31;;The main goal of this project is to study ordered algebraic structures with regard to their applications in game theory. Theory of Riesz spaces, groups, and MV-algebras provide the tools necessary for modeling important aspects of mathematical games, such as economic rationality, strategic invariance, or fairness. This is already witnessed by many parts of game theory: for example, Aumann-Shapley value is a positive equivariant linear operator into the Riesz space of measures and MV-algebras model many coalition games. Our objective is to employ the methods, which were developed for solving deep algebraic and logical problems, in several important game-theoretic problems. Specifically, we will study the class of piecewise linear continuous strategic games by using the polyhedral representation of free MV-algebras and Baker-Beynon duality for unital free vector lattices, with the goal to show the existence of finitely-supported mixed strategy equilibria. We will investigate MV-algebras and their measures in order to model coalition games and their solutions. The motivation is to generalize the Danilov-Koshevoy representation of core by the convex Minkowski combination of simplices for larger classes of games. This inevitably leads to building dual representations of games based on the notion of generalized Moebius transform and the space of filters of an MV-algebra. Each facet of this project is transdisciplinary: the emphasis on algebra and order pervades all the selected game-theoretic scenaria. The presented proposal is an opportunity for the applicant to acquire new mathematical skills under the guidance of a scientist in charge - the specialist in ordered algebraic structures - and achieve thus a unique position in his own research field (game theory, many-valued logics).;241567,6;241567,6;FP7-PEOPLE-2013-IEF;/MC-IEF;UNIVERSITA DEGLI STUDI DI MILANO;IT;;;;0;1;0;0;0;1 185738;621571;CONTRASST;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IOF;FP7;"""Landscape connectivity for Cat species: transcending structures, scales and climates""";2015-01-01;2017-12-31;;'Anthropogenic pressures drive global biodiversity loss. The loss of landscape connectivity, further exacerbated by climate change, is a key driver of species decline. Hence, it is crucial to identify key elements that ensure landscape connectivity across landscapes and scales. Several challenges in this context include insufficient knowledge of 1) species’ eco-physiology across landscapes and ranges, 2) the mechanisms driving migration pulses, 3) how local-scale processes (animal movements) translate to large-scale and longer-term patterns (species’ distributions and range shifts), and consequently, 4) the spatial scale(s) at which connectivity needs to be maintained to mitigate climate change effects on species. These issues are best addressed through comparative studies across a range of landscapes and climates, using umbrella species requiring large areas. Using lynx species in North America and Europe as models, this project will establish an integrative approach across scales to predict functional connectivity for wild felids, specifically by a) determining eco-physiological thresholds to environmental stressors and mechanisms driving dispersal pulses between peripheral and core populations, b) investigating the influence of climate and habitat fragmentation on the genetic structure and eco-evolution of these species, and c) identifying how local-scale processes translate into large-scale patterns of connectivity, species’ distribution and range shifts. Ecological and environmental data across continents will be integrated using groundbreaking eco-physiological and landscape genetics tools, and dynamic simulation modelling (using the novel individual-based model RangeShifter). Spanning 3 years under a careful management plan to ensure feasibility of all 3 chapters, this transdisciplinary project will provide valuable insights and conservation guidelines on how to maintain large-scale connectivity for umbrella species across fragmentation and climate scenarios.';242049,6;242049,6;FP7-PEOPLE-2013-IOF;/MC-IOF;HELMHOLTZ-ZENTRUM FUER UMWELTFORSCHUNG GMBH - UFZ;DE;;;/LIF;0;1;0;0;0;1 110888;603567;GREEN SURGE;ONG;FP7-ENVIRONMENT;ENV.2013.6.2-5;FP7;Green Infrastructure and Urban Biodiversity for Sustainable Urban Development and the Green Economy;2013-11-01;2017-10-31;;"GREEN SURGE will identify, develop and test ways of connecting green spaces, biodiversity, people and the green economy, in order to meet the major urban challenges related to land use conflicts, climate change adaptation, demographic changes, and human health and wellbeing. It will provide a sound evidence base for green infrastructure planning and implementation, exploring the innovation potential, and linking environmental, social and economic services with local communities. Working from the local to the city-regional level, the project aims to: 1) Develop urban green infrastructure as a planning concept for both integration and promotion of biodiversity and ecosystem services, and adapt it to local contexts; 2) apply an innovative biocultural diversity perspective to develop successful governance arrangements facilitating socio-ecological integration and local engagement in planning of urban green spaces; and 3) explore how valuation and real market integration of biodiversity and ecosystem services can facilitate choices in favour of the development of multifunctional green spaces in urban areas. Approaches and tools under these three interlinked objectives will be developed and implemented through an integrative, iterative and transdisciplinary process. GREEN SURGE will embrace a three-tiered approach of comparative European cases, synthesis of good practices, and establishment of five Urban Learning Labs strategically selected to represent different urban situations in Europe. GREEN SURGE will work within cooperative Learning Alliances, a specific type of multi-stakeholder involvement designed to enhance a process of shared learning and understanding in situations with a high degree of complexity and un-predictability. Two-loop learning applied combines a project-wide science-driven approach based on a common framework methodology with a bottom-up knowledge or experience-based approach at the local level.";7189725,6;5701836,95;FP7-ENV-2013-two-stage;/CP;KOBENHAVNS UNIVERSITET;DK;"ECOMETRICA LIMITED;LAVACO PODJETJE ZA GRADBENISTVO IN TRGOVINO DOO;TRIPLE ME HOLDING BV;SCANDINAVIAN BRANDING AS;HELSINGIN YLIOPISTO;METROPOLITAN RESEARCH INSTITUTE LTD.;TISA DOO;TECHNISCHE UNIVERSITAET MUENCHEN;FORESTRY COMMISSION RESEARCH AGENCY;TECHNISCHE UNIVERSITAET BERLIN;SVERIGES LANTBRUKSUNIVERSITET;INSTITUT ZA TRAJNOSTNI RAZVOJ;HUMBOLDT-UNIVERSITAET ZU BERLIN;FUNDACAO DA FACULDADE DE CIENCIAS DA UNIVERSIDADE DE LISBOA FP;C-O-M-B-I-N-E ARKITEKTER AB;WAGENINGEN UNIVERSITY;PROFIN SERVICE SRL;ICLEI EUROPEAN SECRETARIAT GMBH (ICLEI EUROPASEKRETARIAT GMBH)*;UNIWERSYTET LODZKI;UNIVERSITA DEGLI STUDI DI BARI ALDO MORO;SEEBAUER, WEFERS UND PARTNER GBR;UNIVERZA V LJUBLJANI;STOCKHOLMS UNIVERSITET";"UK;SI;NL;DK;FI;HU;DE;SE;PT;IT;PL";/ENV;0;1;0;0;0;1 104507;311933;WATER4CROPS;ONG;FP7-KBBE;KBBE.2012.3.5-03;FP7;Integrating bio-treated wastewater with enhanced water use efficiency to support the Green Economy in EU and India;2012-08-01;2016-07-31;http://www.water4crops.org;"Water4Crops provides a combination of technical improvements in the field of bio-treatment and agricultural water use within a transdisciplinary identification of novel agri-business opportunities. Water4Crops aims at: a) developing innovative biotechnological wastewater treatments for improved water recycling, b) initiating the co-creation of alternative combinations of bio-treatment, recycling of high value elements, and combinations for bioproducts leading to a better commercialization of biotechnology and agricultural products in Europe and India, c)improving water use efficiency at field level through agronomics, plant breeding and locally adapted new irrigation technologies and accurate crop water requirement measurements techniques. Water4Crops will boost bio-based economy by applying a double track approach. First a comprehensive set of key Green-Economy technologies for: 1) valorization of volatile fatty acids; 2) obtaining: natural antioxidants (polyphenols), biopolymers (PHAs), energy (biomethane); 3) new substances for selective recovery of valuable products from wastewater; 4) tailoring effluent properties from decentralized innovative bioreactors; 5) low bio-sludge production by SBBG Reactors; 6) removal of organopollutants by nanobiocatalysts; 7) reduced clogging of wetlands; 8) virus monitoring detection assays; 9) suitable precision irrigation systems for reclaimed water; 10) new monitoring for increase crop water productivity; 11) understanding the genetic mechanisms regulating drought-adaptive traits across maize, sorghum, millet and tomato; 12) optimized waste water related combinations of species/genotypes x environment x management. Second, new product market combinations will be identified. The co-creation process will be organized by two Mirror cases (Emilia Romagna area in Italy and Hyderabad region in India) within a specific Science-Practice Interface (INNOVA platforms). Developing the new applications and business opportunities with regional enterprises and stakeholder will move India and Europe towards a Green Economy.";7696538,99;5973689;FP7-KBBE-2012-6-singlestage;/CP-TP;CONSIGLIO NAZIONALE DELLE RICERCHE;IT;"VLAAMSE INSTELLING VOOR TECHNOLOGISCH ONDERZOEK N.V.;INOFEA AG;DEUTSCHE GESELLSCHAFT FUR INTERNATIONALE ZUSAMMENARBEIT (GIZ) GMBH;UNIVERSITA DEGLI STUDI DI CATANIA;S.T.E.P. RAUTENBACH YUCE GEBEL Consulting GmbH;FACHHOCHSCHULE NORDWESTSCHWEIZ;TM SOLUTIONS LTD;ENVINHEALTH ENVIRONMENTAL NUTRITIONAL AND HEALTH SERVICES AE;BIOPLANTA GmbH;HELMHOLTZ-ZENTRUM FUER UMWELTFORSCHUNG GMBH - UFZ;CONSORZIO DI BONIFICA DI SECONDO GRADO PER IL CANALE EMILIANO ROMAGNOLO CANALE GIANDOTTI;HORTA SRL;INSTITUT NATIONAL DE RECHERCHE EN SCIENCES ET TECHNOLOGIES POUR L'ENVIRONNEMENT ET L'AGRICULTURE;SIMA-TEC GMBH;VITA 34 AG;ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA;INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE;INOFEA GMBH;UNIVERSITA DEGLI STUDI DI ROMA LA SAPIENZA;POLYTECHNEIO KRITIS;PHYTOREM SA;BIONACTIS INTERNATIONAL GROUP (BIG)SA;STICHTING WAGENINGEN RESEARCH;NATURAL ENVIRONMENT RESEARCH COUNCIL";"BE;CH;DE;IT;EL;FR;NL;UK";/SCI;0;1;0;0;0;1 185438;340828;EPNET;ONG;FP7-IDEAS-ERC;ERC-AG-SH6;FP7;Production and distribution of food during the Roman Empire: Economics and political dynamics;2014-03-01;2019-02-28;;"The project aims at detecting and defining the political and economic dynamics of the Roman Empire trade system by designing and implementing an experimental laboratory to explore different historical hypoteses through computer simulations. Empirical data will be used to correct and validate the results of the simulations and define rigourous and falsifiable models of ancient trade sytems. The Roman Empire trade system is generally considered to be the first complex European trade network. Many theories and hypotheses about its organization have been proposed but no formal model has been put forward so far. We propose to study this system using complex network analysis, formal modelling and computer simulation. The different existing research hypotheses will be modelled in a formal framework that will be used for running computer simulations and create possible scenarios of the development of the trade network. The archaeological and historical datasets will offer the means for validation processes in order to verify the explanatory power of the different models and to choose the best-fitting representation of the investigated phenomena. The project counts with one of the richest database for amphorae and epigraphy, one of the most precise archaeological and historical semantic markers available for the Roman Empire market. They provide information on geographical origin, the products transported and traded, economic transactions, as well as the social position and relationships between the traders. The project will provide the research community with a powerful tool for the study and interpretation of past political and economic systems, which will benefit our understanding of long-term social trajectories. This will be achieved through an innovative methodology based on transdisciplinarity and therefore will constitute a groundbreaking in the field of historical studies.";2432056;2432056;ERC-2013-ADG;/ERC-AG;UNIVERSITAT DE BARCELONA;ES;"SIRIS ACADEMIC SL;BARCELONA SUPERCOMPUTING CENTER - CENTRO NACIONAL DE SUPERCOMPUTACION";ES;/SOC;0;1;0;0;0;1 93869;241062;JEWCOM;ONG;FP7-IDEAS-ERC;ERC-SG-SH5;FP7;History of European -Jewish Communication in the 20th Century;2010-02-01;2015-01-31;;The project focuses on European - Jewish communication about political and socio-historical events as well as on private discussions. 10 significant correspondences written by German speaking Jewish authors in the 20th century travelling through Europe, Palestine/Israel and to the US, will be analysed to examine how an individual memory as part of the cultural area Europe is shaped. The aim of the project is to examine the interferences of individual and cultural memory in order to show that cultural memory is mainly structured through individual perception. Prof. von Jagow proposes that beyond traditions of describing cultural memory in a historic way the analyses of the letters can widen the perspective because letters as ego-documents are a medium of private and public discussion. Although it is unconventional to analyse a history of European-Jewish communication on the basis of letters, it is evident that these sources open completely new horizons on cultural memory by a theoretical approach beyond the state-of-the art which stems from transdisciplinary methodology. It is grounded in the fact that literary documents are of highest cultural and anthropological value. The project is centered in a highly advanced theoretical approach of history from below centered in emphasizing subjectivity. Works of art are of extraordinary value taking into consideration that they are both: a seismographic code of political and socio-historical reflections and a personal and aesthetic perspective upon. As an another companion of Jewish writing and thought, a history from below emphasizes on subjectivity and perception in order to enlarge the European-Jewish memory in a completely new approach to cultural remembering. This approach is of general interest not only in literary critics, but also in other disciplines like in history, history of science and medicine and ethics.;600000;600000;ERC-2009-StG;/ERC-SG;UNIVERSITAT ERFURT;DE;;;/SOC;0;1;0;0;0;1 89129;230274;EMOTIONS;ONG;FP7-IDEAS-ERC;ERC-AG-SH6;FP7;The social and cultural construction of emotions: The Greek paradigm;2009-01-01;2013-12-31;;"Emotions influence social relations; consequently, they are socially relevant, subject to scrutiny, judgment, and normative intervention. The manifestation, perception and treatment of emotions are subject to social interventions and to the influence of cultural change. Emotions in the Classical world have been primarily studied in the light of their representation in literature and art. Such studies have provided important insights; yet, they are based on works primarily created in a few major urban centres, almost exclusively by educated men of a higher status. This project is based on an analysis of documentary sources (inscriptions and papyri, c. 800 BC-c. 500 AD). Although they provide abundant, diverse, and representative evidence, they have never been studied in connection with this subject. As compared to literature and art, these sources represent a wide range of social strata and age-classes, originate in both genders, and are widely disseminated over time and space. These sources will be analysed both diachronically (history of particular emotions) and synchronically (manifestations of emotions in defined historical contexts). Selected literary sources and archaeological material will also be taken into consideration. The project pursues the following objectives: to contribute to a more reliable, nuanced, and comprehensive history of emotions in the Greek world; to increase awareness of the importance of emotions in Classical studies; to contribute to the transdisciplinary study of emotions through the presentation of paradigms from Classical antiquity; to enhance the dialogue between historical, social, and natural sciences; and to make documentary sources accessible to scholars working on the history of emotions and, more generally, on the history of mentality.";1593945;1593945;ERC-2008-AdG;/ERC-AG;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;UK;;;/SOC;0;1;0;0;0;1 111513;613169;TRANSIT;ONG;FP7-SSH;SSH.2013.3.2-1;FP7;Transformative Social Innovation Theory project;2014-01-01;2017-12-31;;"The aim of TRANSIT (Transformative Social Innovation Theory) is to build a theory of social innovation that is useful not only to academics, but also to policy makers, social entrepreneurs, and other stakeholders. The starting point for TRANSIT is the need to understand transformative social innovations: social innovations that contribute to systemic changes that address urgent societal challenges. TRANSIT unpacks the relation between social innovation and systemic change in the context of a rapidly changing world that faces ‘game changing’ developments (e.g. financial crisis, climate change or the ICT-revolution). TRANSIT will explore constituent links in the causal chain between social innovation and systemic change. The main research question is: How and under what conditions do social innovations lead to systemic change, and how are actors (dis)empowered in transformative social innovation processes? TRANSIT will develop a new theory of transformative social innovation, drawing upon a range of existing theoretical and methodological approaches to innovation and social change, and using a systems innovation and sustainability transition research framework as a starting point. Empirically, TRANSIT takes an embedded case-study approach to conduct a multi-leveled, cross-national comparative analysis of social innovation projects and networks across Europe and Latin America, combining in-depth case-study analysis with quantitative meta-analysis. The new theory of transformative social innovation is thus both grounded in in-depth case-studies as well as tested and generalised in a cross-national data-base. The research concept of TRANSIT is to create an iterative interplay between: empirical research on social innovation; the development of a new empirically-grounded theory of transformative social innovation; and transdisciplinary translation to capacity building tools to be co-developed with policy-makers, civil society organisations and social entrepreneurs.";6219344,8;4939081;FP7-SSH-2013-1;/CP-IP;DUTCH RESEARCH INSTITUTE FOR TRANSITIONS BV;NL;"UNIVERSITY OF EAST ANGLIA;INSTITUTE FOR HOUSING AND URBAN DEVELOPMENT STUDIES BV;FUNDACAO COORDENACAO DE PROJETOS PESQUISAS E ESTUDOS TECNOLOGICOS COPPETEC;UNIVERSITEIT MAASTRICHT;UNIVERSITE LIBRE DE BRUXELLES;THE UNIVERSITY OF SUSSEX;UNIVERSITAET FUER BODENKULTUR WIEN;ESSRG Kft.;UNIVERSIDAD NACIONAL DE QUILMES;UNIVERSIDADE DA CORUNA;AALBORG UNIVERSITET";"UK;NL;BR;BE;AT;HU;AR;ES;DK";"/SOC;/POL";0;1;0;0;0;1 105479;309731;StrokeTherapy;ONG;FP7-IDEAS-ERC;ERC-SG-LS5;FP7;Improving arm and hand function after stroke with clinically-relevant delivery of neurotrophin-3 to elderly disabled muscles: from rats to humans;2012-11-01;2017-10-31;;"Stroke disables millions worldwide and costs the EU €38 billion each year. Excitingly, my team has identified a clinically-feasible therapy for stroke which reverses disability in rats when given in a clinically-relevant time frame. Specifically, we have shown that the human growth factor neurotrophin 3 (NT3) promotes locomotor recovery and reverses sensory neglect in adult rats when infused into disabled arm muscles, starting 24 hours after stroke. Importantly, Phase II clinical trials have shown that systemic, repeated high doses of neurotrophin-3 are safe and well-tolerated in humans with other conditions. This paves the way for a Phase II trial in humans after stroke. We now wish to maximise arm and hand (paw) recovery in elderly rats with larger strokes by optimising dose, timing and route. We will then submit for approval a Clinical Trial Application for a randomised, double-blinded, placebo-controlled Phase II human clinical trial to treat stroke using NT3. We also propose multidisciplinary, cutting-edge studies to understand how NT3 promotes plasticity in the brain and spinal cord. 1) We will use wireless neural recording in awake rats and functional brain imaging to study plasticity after stroke and NT3 treatment. 2) Our innovative “RatBot” will automatically train, rehabilitate and assess grasping of pellet food. 3) To reveal where NT3 is transported we will track a novel tagged version of NT3 in vivo. 4) In an ambitious final study we will maximise recovery of arm and hand function in elderly rats when treatments are delayed by 1 month after larger strokes. In summary, we propose a high-risk, high-yield, transdisciplinary, innovative programme of work to maximise sensory and motor recovery after stroke in elderly rats. Treatment will be initiated in a clinically-relevant time frame (after 24 hours or 1 month) using a clinically-relevant dose and duration of treatment via a clinically-straightforward route, ready for a Phase II clinical trial.";1499909;1499909;ERC-2012-StG_20111109;/ERC-SG;KING'S COLLEGE LONDON;UK;;;"/BIO;/LIF";0;1;0;0;0;1 99423;265394;FARMPATH;ONG;FP7-KBBE;KBBE.2010.1.4-03;FP7;Farming Transitions: Pathways Towards Regional Sustainability of Agriculture in Europe;2011-03-01;2014-05-31;;In FarmPath, we propose that increasing sustainability in agriculture is best addressed by enabling flexible combinations of farming models, which vary to reflect the specific opportunity sets embedded in regional culture, agricultural capability, diversification potential, ecology, and historic ownership and governance structures. We will enable progress towards this goal of increased regional sustainability of agriculture through a transdisciplinary research approach, where knowledge is co-produced by scientists, stakeholders and practitioners. FarmPath will specifically integrate theoretical and conceptual approaches to transition and transition management with recent research on adaptive capacity and resilience in farming systems, food regimes, and farm level transitions to multifunctionality, and build on previous EC funded research projects on sustainability and innovation in farming systems, and production and consumption chains. FarmPath will assess a set of farm and regional level sustainability initiatives to identify conflict and complementarity, focusing on how combinations of initiatives, actors, technologies and policies can achieve synergies which initiate transition pathways at regional level. FarmPath will engage in participatory visioning and scenario assessment in contrasting national and European regions, to identify transition pathways: combinations of visions and the social and technical mechanisms and innovations needed to reach these visions. This will lead to the development of a handbook for assessing and identifying actions which can be taken by policy makers to facilitate transition towards regionally sustainable agriculture. FarmPath will also investigate issues surrounding young people and new entrants to farming in specific relation to these initiatives and scenarios. Research findings will be presented and discussed in an international conference, and developed into an academic book.;2068272,8;1498893;FP7-KBBE-2010-4;/CP-FP;THE JAMES HUTTON INSTITUTE;UK;"UNIVERSIDADE DE EVORA;UNIVERSITY OF NATIONAL AND WORLD ECONOMY;UNIVERSITY OF PLYMOUTH;AGRICULTURAL UNIVERSITY OF ATHENS;UNIVERSITAET FUER BODENKULTUR WIEN;THE MACAULAY LAND USE RESEARCH INSTITUTE;INSTITUT SUPERIEUR DES SCIENCES AGRONOMIQUES, AGROALIMENTAIRES, HORTICOLES ET DU PAYSAGE;CESKA ZEMEDELSKA UNIVERZITA V PRAZE;VEREIN FUR LANDLICHE STRUKTURFORSCHUNG EV*INSTITUT FUR LANDLICHE STRUKTURFORSCHUNG AN DER JOHANN WOLFGANGGOTHE-UNIVERSITAT";"PT;BG;UK;EL;AT;FR;CZ;DE";"/SOC;/AGR;/ITT";0;1;0;0;0;1 110482;603447;HERCULES;ONG;FP7-ENVIRONMENT;ENV.2013.6.2-7;FP7;Sustainable futures for Europe’s HERitage in CULtural landscapES: Tools for understanding, managing, and protecting landscape functions and values;2013-12-01;2016-11-30;;"European cultural landscapes are valued as everyday living environment, countryside, heritage, scenery with aesthetic and recreational qualities and unique biodiversity, and as a source of ecosystem services that they provide to society. Cultural landscapes, however, are undergoing rapid and fundamental transformations across Europe, mainly as a result of an on-going polarization of land use, with abandonment and rural exodus on the one hand, and intensification and (peri-) urbanisation on the other. So far, substantial challenges have inhibited the design of effective responses to safeguard cultural landscape values. The proposed HERCULES project strives for the empowerment of public and private actors to protect, manage, and plan for sustainable landscapes of significant cultural, historical, and archaeological value at local, national, and pan-European scales. By applying and developing innovative technologies and tools for assessing and mapping cultural landscapes, the project will (a) synthesise existing knowledge on drivers, patterns, and outcomes of persistence and change in Europe’s cultural landscapes; (b) perform targeted case studies to develop in-depth insights on dynamics and values of cultural landscapes; (c) develop a typology of cultural landscapes and scale-up case study insights using observations and landscape modelling; (d) develop visions for re-coupling social and ecological components in cultural landscapes and translate them into policy and management options; and (e) design and implement a community-based Knowledge Hub for Good Landscape Practice and demonstrate it with land users, agencies, SMEs, and citizen associations. HERCULES comprises European universities, SMEs, NGOs, and a research institute that are leaders in landscape science and practice. The project follows the European Landscape Convention’s call for transdisciplinary research and involves all actors with stakes in cultural landscapes of historical and archaeological value.";3848517,41;2956973,01;FP7-ENV-2013-two-stage;/CP;HUMBOLDT-UNIVERSITAET ZU BERLIN;DE;"SINERGISE LABORATORIJ ZA GEOGRAFSKE INFORMACIJSKE SISTEME DOO;STICHTING VU;ALBERT-LUDWIGS-UNIVERSITAET FREIBURG;KOBENHAVNS UNIVERSITET;FOREST COMMUNICATION NETWORK LTD;UPPSALA UNIVERSITET;LANDSCAPE RESEARCH GROUP LIMITED;EUROPEAN LANDOWNERS ORGANIZATION;EIDGENOESSISCHE FORSCHUNGSANSTALT WSL;ALTICIME;PEREZ GIROD GENEVIEVE;NORDISK FOND FOR MILJ? OG UDVIKLING;PANEPISTIMIO AIGAIOU;TALLINN UNIVERSITY";"SI;NL;DE;DK;UK;SE;BE;CH;FR;EL;EE";/ENV;0;1;0;0;0;1 110573;603654;ARTS;ONG;FP7-ENVIRONMENT;ENV.2013.6.2-3;FP7;Accelerating and Rescaling Transitions to Sustainability;2013-12-01;2016-11-30;;The objective of ARTS is to benefit policy, practice and theory related to accelerating sustainability transitions and to create opportunities for innovation (including social innovation) by coupling, rescaling and accelerating sustainability initiatives in European city-regions. ARTS will create interfaces between policy, practice and theory that are spaces for co-creation, theory building, policy experimentation, social innovation and learning. ARTS will have an aggregated impact on transition regions, on national and European policy related to facilitating transitions, and on theory and governance of sustainability transitions. The focal unit of analysis will be innovative activities and related actor-networks that are fundamentally changing energy, food, shelter and mobility provisioning patterns at the scale of a city or region, situated within a wider European context. ARTS will explore how lessons from these initiatives can be drawn for broader transitions to sustainable low-carbon European societies. We seek to identify the values, conditions and mechanisms for accelerating sustainability transitions, develop strategies to assist and stimulate their acceleration and assess them with dynamic modelling approaches. We will explore these conditions based on a diverse set of transition initiatives in five regions across Europe in an inter- and transdisciplinary way: Brighton, Budapest, Dresden, Flanders, and Stockholm. The developed acceleration governance approach and modelling platform, support decision making, and social learning processes to speed-up the implementation of EU’s Sustainable Development and Biodiversity Strategies. They deliver to the energy targets (20/20/20 targets, the EU Energy Strategy), and the targets addressed in the Roadmaps (2050-Competitive Low-carbon Economy, Resource Efficient Europe), while supporting transitions to innovative (Innovation Union Flagship Initiative) socially sustainable (2020 Growth Strategy) low-carbon societies.;3705221,38;2996826;FP7-ENV-2013-two-stage;/CP;DUTCH RESEARCH INSTITUTE FOR TRANSITIONS BV;NL;"VLAAMSE INSTELLING VOOR TECHNOLOGISCH ONDERZOEK N.V.;AIT AUSTRIAN INSTITUTE OF TECHNOLOGY GMBH;KOZEP-EUROPAI EGYETEM;GAK OKTATO, KUTATO ES INNOVACIOS NON PROFIT KOZHASZNU KORLATOIT FELELOSSEGU TARSASAG;LEIBNIZ-INSTITUT FUR OKOLOGISCHE RAUMENTWICKLUNG EV;THE UNIVERSITY OF SUSSEX;LANCASTER UNIVERSITY;ERASMUS UNIVERSITEIT ROTTERDAM;ICLEI EUROPEAN SECRETARIAT GMBH (ICLEI EUROPASEKRETARIAT GMBH)*;BOGAZICI UNIVERSITESI;STOCKHOLMS UNIVERSITET;PENNANT RENDEZVENYSZERVEZESI ES KULTURALIS SZOLGALTATO BETETI TARSASAG";"BE;AT;HU;DE;UK;NL;TR;SE";/ENV;0;1;0;0;0;1 110497;603705;TESS;ONG;FP7-ENVIRONMENT;ENV.2013.6.2-3;FP7;Towards European Societal Sustainability;2013-12-01;2016-11-30;;Transitions to low-carbon societies take place at multiple and complementary scales. Transition processes are highly dependent on the innovative potential of community-based initiatives and their articulation with appropriate institutional architecture. Community-based initiatives are potentially more adaptable and less constrained by current structural circumstances than top-down policies and can give impetus to large-scale and technology driven changes. TESS will provide an understanding on the upscaling possibilities of such high-potential community-based initiatives by addressing two main questions: What is the impact of community-based initiatives in terms of carbon reduction potential and economic effect? What institutional structures (values, policies and mechanisms) support these initiatives in persisting beyond the initial phase and moving into an acceleration phase, spreading desired impacts? Answers will be provided through (1) a novel measuring, reporting and verification (MRV) framework for benchmarking community-based initiatives. This will enable quantifiable, comparable and standardised evaluation, and (2) the identification of success factors for the emergence, persistence and diffusion of promising initiatives, including online initiatives. We will identify these initiatives through case studies across regions and sectors and produce a systemic understanding of their impact on societal transitions towards sustainability. Our research will be integrated and transdisciplinary, with the unique opportunity to bring together social and natural scientists to foster a transition towards European societal sustainability. Our work will feed into and extend the Climate Adapt database to facilitate reconciliation of mitigation and adaptation and connect to Europe wide evaluation approaches such as the Common Monitoring and Evaluation Framework (CMEF) of the Rural Development Programmes.;3614377,4;2841563;FP7-ENV-2013-two-stage;/CP;POTSDAM INSTITUT FUER KLIMAFOLGENFORSCHUNG;DE;"UNIVERSITATEA STEFAN CEL MARE DIN SUCEAVA;THE JAMES HUTTON INSTITUTE;OULUN SEUDUN KOULUTUSKUNTAYHTYMA OSEKK;CLIMATE FUTURES LIMITED;T6 ECOSYSTEMS SRL;UNIVERSITAT AUTONOMA DE BARCELONA;OULUN AMMATTIKORKEAKOULU OY;UNIVERSITA DEGLI STUDI DI ROMA LA SAPIENZA";"RO;UK;FI;IT;ES";/ENV;0;1;0;0;0;1 106722;320303;DESAFIO;ONG;FP7-SSH;SSH.2012.2.1-2;FP7;DEMOCRATISATION OF WATER AND SANITATION GOVERNANCE BY MEANS OF SOCIO-TECHNICAL INNOVATION;2013-02-01;2015-07-31;http://www.desafioglobal.org;DESAFIO means “challenge” in both Portuguese and Spanish. The guiding concept of our proposal is to make a contribution towards tackling what is arguably one of the major challenges facing Brazil and Latin American countries in the 21st century: eradicating structural social inequality in the access to essential water and sanitation services. The overarching objective of our proposal is assessing existing experiences and developing new strategies that bring about sustainable, appropriate, and innovative socio-technical solutions to foster economic and social development through social transformation in vulnerable communities, particularly with reference to access to safe water supply and sanitation in urban, peri-urban, and rural areas of South America, with a particular emphasis on Brazil. These strategies will be developed through research and networking that actively engages beneficiary communities, practitioners, local authorities, and other relevant actors in their planning, design, assessment, implementation, monitoring, validation, and diffusion. Our transdisciplinary approach is predicated on a close interaction with non-academic actors in the production and validation of knowledge, among other things to underpin policy and behavioural transformations. We have selected a number of case studies that will cover a range of situations and characteristics, from informal settlements in the urban periphery of world megacities (Rio de Janeiro, Brazil) and in peri-urban areas of provincial capitals (Cali, Colombia), favelas located in the heart of booming mid-range urban centres (Recife, Brazil), to small rural villages (Mondomo, Colombia) and communities in semi-arid areas (Ceará and Minas Gerais, Brazil and Santa Fe, Argentina). We will endeavour to draw lessons and develop recommendations that are applicable to other socio-cultural and economic contexts across the developing world.;1326374,72;999972,8;FP7-SSH-2012-2;/CP-FP-SICA;UNIVERSITY OF NEWCASTLE UPON TYNE;UK;"UNIVERSIDADE FEDERAL DE MINAS GERAIS;UNIVERSIDADE FEDERAL DO RIO DE JANEIRO;UNIVERSIDADE FEDERAL DE PERNAMBUCO;IMAR- INSTITUTO DO MAR;COMPANHIA DE AGUA E ESGOTO DE CEARA SEM CAGECE;UNIVERSIDAD DEL VALLE;UNIVERSIDAD NACIONAL DE ROSARIO - UNR";"BR;PT;CO;AR";/SCI;0;1;0;0;0;1 87747;210680;BIOSTRUCT;ONG;FP7-IDEAS-ERC;ERC-SG-PE1;FP7;Multiscale mathematical modelling of dynamics of structure formation in cell systems;2008-09-01;2013-08-31;;"The aim of this transdisciplinary project is to develop and analyse multiscale mathematical models of pattern formation in multicellular systems controlled by the dynamics of intracellular signalling pathways and cell-to-cell communication and to develop new mathematical methods for the modelling of such complex processes. This aim will be achieved through a close collaboration with experimental groups and comprehensive analytical investigations of the mathematical problems arising in the modelling of these biological processes. The mathematical methods and techniques to be employed will be the analysis of systems of partial differential equations, asymptotic analysis, as well as methods of dynamical systems. These techniques will be used to formulate the models and to study the spatio-temporal behaviour of solutions, especially stability and dependence on characteristic scales, geometry, initial data and key parameters. Advanced numerical methods will be applied to simulate the models. This comprehensive methodology goes beyond the state-of-the-art, since usually the analyses are limited to a single aspect of model behaviour. Groundbreaking impacts envisioned are threefold: (i) The project will contribute to the understanding of mechanisms of structure formation in the developmental process, in the context of recently discovered signalling pathways. In addition, some of the factors and mechanisms playing a role in developmental processes, such as Wnt signalling, are implicated in carcinogenesis, for instance colon and lung cancer. (ii) Accurate quantitative and predictive mathematical models of cell proliferation and differentiation are important for the control of tumour growth and tissue egeneration; (iii) Qualitative analysis of multiscale mathematical models of biological phenomena generates challenging mathematical problems and, therefore, the project will lead to the development of new mathematical theories and tools.";750000;750000;ERC-2007-StG;/ERC-SG;RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG;DE;;;"/PSE;/MST";0;1;0;0;0;1 109757;612615;KNOWHOW;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IRSES;FP7;Knowledge production, communication and negotiation for coastal governance under climate change;2014-01-01;2016-12-31;;"The overall objective of KnowHow is to improve the capacities of participant institutions and researchers in producing, translating and effectively delivering scientific knowledge to decision makers, with an emphasis on local governments on the coastal zone as key actors in adaptation to global environmental change, particularly climate change. Its specific objectives are: 1) Promote exchange of expertise and experience between partners in modes of research oriented towards the needs of decision makers in the domain of environmental governance. These include all spheres of government from national to local with a specific focus on municipal government; 2) Develop and test a methodological approach to assess local governments’ knowledge needs for coastal adaptation to climate change which is transposable between Europe and Africa; 3) Improve existing capacity of partners to conceptualise and communicate research and research uncertainties in ways that enhance its usability, comprehension and impact; 4) Develop a joint stakeholder-oriented transdisciplinary research proposal for a next FP call that will contribute to more effective management of coastal zones in a changing climate. KnowHow involves one organisation from South Africa (S&T Agreement Country), the Council for Scientific and Industrial Research (CSIR); and three European Partners: the Faculty of Social Sciences and Humanities of Nova University of Lisbon (FCSH), Portugal; the Climate Service Centre (CSC) of the Helmholtz-Zentrum Geesthacht, Germany; Delft University of Technology (TUDelft), Netherlands; and University of Bergen, Norway (UiB).";281400;281400;FP7-PEOPLE-2013-IRSES;/MC-IRSES;FACULDADE DE CIENCIAS SOCIAIS E HUMANAS DA UNIVERSIDADE NOVA DE LISBOA;PT;"HELMHOLTZ-ZENTRUM GEESTHACHT ZENTRUM FUR MATERIAL- UND KUSTENFORSCHUNG GMBH;UNIVERSITETET I BERGEN;TECHNISCHE UNIVERSITEIT DELFT";"DE;NO;NL";/LIF;0;1;0;0;0;1 107938;330057;Local Turn;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IEF;FP7;A local turn in migrant integration policies? Local citizenship and integration policy appraches in the context of multi-level governance in Europe;2013-06-01;2015-05-31;;"This project proposal aims to analyse the existing scope for European cities to develop policies for migrant integration in multi-level governance systems. The role of lower tiers of governance, and that of cities in particular, is receiving growing attention from both researchers and policy-makers as the potential of cities to influence social inclusion and the weakening force of national citizenship models are recognised. Much-needed, systematic comparisons of local approaches to migrant integration remain scarce. Addressing this issue, this project will look at the scope left to the local level to develop integration policies within multi-level governance frameworks, and explore the convergence of local approaches in Europe. It will do so by 1) mapping policy developments regarding the multi-level governance of migrant integration in the EU; 2) conducting an in-depth comparison of integration policy approaches of pairs of cities in three different national contexts; and 3) analysing the degree of convergence of integration policies in cities towards measures for fostering local forms of citizenship in Europe. The project uses a transdisciplinary (or intersectoral) approach by closely involving an existing working group of integration policy makers from big European cities in the research process.";166336,2;166336,2;FP7-PEOPLE-2012-IEF;/MC-IEF;UNIVERSIDAD POMPEU FABRA;ES;;;/SCI;0;1;0;0;0;1 107226;327538;SCECI;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IEF;FP7;Scientific Concepts of Emotion and Cultural Identities;2013-07-01;2015-06-30;;"This project will investigate (a) the scientific concepts of emotion that psycho-medical research has produced between 1950 and 2000, and (b) if and how these concepts have informed emotional culture and identity in post-industrial societies in Western Europe—assessed through cultural productions such as film. The innovative character of this proposal lies in its subject and in its transdisciplinary approach that integrates expertise in psycho-medical research into current historical and cultural debate. It will develop a new frame for analysis that seeks to bridge the remaining conceptual gap in scholarship on emotion. In the first year, the researcher will join the project “Emotional Culture and Identity” (CEMID) of the Institute for Culture and Society (ICS) at the Universidad de Navarra. During this phase the applicant will receive excellent training in cultural analysis at the ICS that currently hosts nearly 60 researchers of various academic disciplines (philosophy, sociology, economics, political science, communication, medicine, biology, etc.) and of 16 different nationalities. The knowledge and experience that is obtained in Navarra will be put to use in the writing phase to be carried out in the second year, partly at the researcher’s home institution, the Max Planck Institute for Human Development, in order to create lasting synergies in the cultural analysis of emotion. By facilitating future collaborations between Spanish and German social science research centers on emotion research the proposed project will greatly contribute to EU excellence and competitiveness, and enable the researcher to pursue her goals of completing her postdoctoral academic training and becoming a successful tenure track professor.";230036,6;230036,6;FP7-PEOPLE-2012-IEF;/MC-IEF;UNIVERSIDAD DE NAVARRA;ES;;;/SCI;0;1;0;0;0;1 108791;603941;SEFIRA;ONG;FP7-ENVIRONMENT;ENV.2013.6.5-2;FP7;Socio-economic implications for individual responses to Air Pollution Policies in EU +27;2013-06-01;2016-05-31;http://www.sefira-project.eu/;"SEFIRA has the objective of creating a European coordination of transdisciplinary scientific and socio-economic resources in order to support the review and implementation of air quality legislation by the European Commission (EC) led by DG Environment. The EC has now given increased attention to the socio-economic dimension of air quality policies in order to improve their effectiveness and acceptability. SEFIRA will coordinate some of the best scientific and socio-economic resources and will review air quality policies and legislation at the interface between environmental, economic and social sciences in order to achieve a deeper understanding of these complex issues. Individual behaviours and choices will be analysed in a socio-economic context ranging from the local to the European level. The main fields involved in the action will be atmospheric sciences, environmental and legal sociology, anthropology, geography and economics. The integration of disciplines, the relationship with the most relevant stakeholders and an effective coordination between the SEFIRA consortium and other European projects in the same field will be a priority. The project strategy will support the development of a new European appraisal of problems and resources in the field, will deploy a pilot survey and a test of policy implementation by innovative models of individual choices analysis and ecosystem services valuation. Stakeholders will be involved from the beginning of the project in a process of dialogue and cooperative problem solving in order to ensure relevance and robustness as the work progresses from local to European level.";1196467,88;998000;FP7-ENV-2013-one-stage;/CSA-CA;Universita' degli Studi di Urbino Carlo Bo;IT;"UNIVERSITAT WIEN;SZKOLA GLOWNA HANDLOWA W WARSZAWIE;PRAGMA SRL;CONSIGLIO NAZIONALE DELLE RICERCHE;INTERNATIONALES INSTITUT FUER ANGEWANDTE SYSTEMANALYSE;LUNDS UNIVERSITET;KATHOLIEKE UNIVERSITEIT LEUVEN;KING'S COLLEGE LONDON";"AT;PL;IT;SE;BE;UK";/ENV;0;1;0;0;0;1 103918;290976;SCIENCEFORE;ONG;FP7-IDEAS-ERC;ERC-AG-ID1;FP7;The Science of Forecasting: Probabilistic Foundations, Statistical Methodology and Applications;2012-06-01;2018-02-28;;"The future being uncertain, forecasts ought to be probabilistic in nature, taking the form of probability distributions over future quantities or events. Accordingly, a transdisciplinary transition from point forecasts to probabilistic forecasts is well under way. The ScienceFore project seeks to provide guidance and leadership in this transition, by developing the theoretical foundations of the science of forecasting, as well as cutting-edge statistical methodology, along with applications in meteorology and economics. Theoretically, we will focus on the study of aggregation methods for the combination of multiple probabilistic forecasts for the same quantity or event, and on the design and structure of performance measures that encourage truthful predictions, including but not limited to proper scoring rules. In applications, we will develop statistical postprocessing techniques for the THORPEX Interactive Grand Global Ensemble (TIGGE), which comprises the world's leading global numerical weather prediction models. The key challenge is to retain physically realistic and coherent joint dependence structures across meteorological variables, continents and oceans, and look-ahead times. Furthermore, we will investigate the use of statistical postprocessing techniques in macroeconomic surveys, and aim to resolve a long-standing puzzle in the evaluation of economic and financial forecasts. Theory and applications will intertwine closely, to result in a project that constitutes much more than the sum of its parts. For example, the study of the properties of aggregation methods will inform the development of postprocessing methods for ensemble weather forecasts, and decision theoretically principled approaches to the design of performance measures call for a change of paradigms in the practice of the generation and evaluation of point forecasts, to be demonstrated in case studies.";1726793,89;1726793,89;ERC-2011-ADG_20110209;/ERC-AG;HITS GGMBH;DE;RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG;DE;/SCI;0;1;0;0;0;1 107192;327173;DISPUTING GENDER;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IOF;FP7;Disputing gender. Understanding how psychological gender research is used in public scientific controversies on gender in US-American media;2013-05-01;2016-04-30;;The proposed transdisciplinary project analyzes socioscientific controversies on gender in US-American media. The notion socioscientific controversy entails public debates in which social questions are debated with the help of science. This project focuses on public debates about gender relations in which participants draw on psychological gender research. The analysis starts with a controversy sparked when in 2005, the president of Harvard University suggested that the lack of woman scientists in higher scientific positions might be due to innate cognitive gender differences. The following public debate included psychologists who used psychological gender research to either confirm or reject this position. The project will draw on discourse analysis to analyze this public debate and similar socioscientific controversies in selected US-American media. Research questions are directed at the ways in which psychological gender research shapes what can be publicly said about gender. Context information is drawn on to clarify the relation between public scientific discourse on gender and factual gender inequalities. Results will be discussed in the light of the critical historiography of psychology, science studies approaches on public scientific controversies, and feminist reflections on the interpenetration of science and gender inequalities. The project aims to contribute both theoretically and empirically to a critical historiography of psychology by analyzing and defining the relation between psychology and social inequalities, to science studies approaches on socioscientific controversies by clarifying how socioscientific controversies mediate between scientific and public discourse, and to feminist studies on the relation between science and social inequalities with an exemplary analysis and a detailed reflection of the interpenetration between psychological gender research and gender inequalities.;227592;227592;FP7-PEOPLE-2012-IOF;/MC-IOF;Sigmund Freud Privatuniversitat Wien GmbH;AT;;;/LIF;0;1;0;0;0;1 108493;330709;RDM;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IEF;FP7;Risky Decision-Making: Opening the Human Black Box to Document Decision-Making;2014-02-03;2016-07-04;;"How can we analyse real decision-making (DM) processes in organizations to prevent or mitigate industrial risks? The main purpose of the proposal is to acquire a better understanding of DM’s psycho-social mechanisms in organizations to improve them and so that, mitigate and/or prevent risks. Managing risk is a priority for ensuring safety and continuous performance. Reason (Reason, 2000) shows how accidents happen when a series of ‘threats’ to safety occur and pass unnoticed through ‘gaps’ in an organization protective system. The actual sequence of actions and decisions in hazardous operations can help to understand, and therefore prevent or mitigate such propagation of failures. However, this needs to document it, and gathering such data is a gap in many organizations. Our research and operational question is therefore: “How can we gather and study real-world data on decision-making in risky situations?” Following the flight recorders’ example, this research project proposes to develop a method to collect DM in hazardous situations, based on a human-centered “cognitive black box”. It will develop an in situ collect and analysis kit for experts’ DM and thinking process by combining a wearable first-person perspective video capture device, called subcam, and protocol for on-the-fly capture of workers’ mental processes. This technique will be used to investigate some real-world cases (in LSE ethics committees and EDF managers’ meetings). The main decision-makers will be equipped with the subcam, then debriefed. The proposed research is a breakthrough in psychology and decision science. Our approach is radically innovative in terms of risks prevention and mitigation in that it not only provides a new path for scientific investigation, but opens the way to industrial applications in many industries, through an innovative and transdisciplinary approach in social sciences.";221606,4;221606,4;FP7-PEOPLE-2012-IEF;/MC-IEF;LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE;UK;;;/SCI;0;1;0;0;0;1 95336;252079;EU NETWORKS;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IEF;FP7;Networks in European Law;2010-09-01;2012-08-31;;The proposed research aims to examine the way in which ‘networks’, resulting from the cooperation of public and/or private actors, are increasingly established under European Law. The research project analyzes the networks from both the institutional and the functional perspectives and, specifically, considers the networks established for the enforcement and the harmonization of European Law. This goal will be pursued by adopting a methodology that relies on a transdisciplinary approach to the study of Law (e.g. an approach that crossed over the traditional boundaries of private and public laws), and the suggestions coming from other disciplines (e.g. political sciences, sociology), especially with respect to the possibility to apply methods for research (e.g. the interviews) well known in certain disciplines, but not so often used in approaching EU Law. In particular, this research will concentrate on the following two case-studies. The first case-study regards the networks of public authorities and courts adopted to enforce Consumer Law and Competition Law (i.e. the Consumer Cooperation Regulation Network and the European Competition Network, “CPC” and “ECN”). The second case-study concerns the private-based networks that have been introduced to harmonize product safety standards and that are now under development within the ‘New Legislative Framework’ (i.e. the European Standardization Organizations, “ESOs”). The research project will also examine the role played by these European networks in the ‘international arena’, and, precisely, the role of the CPC and the ECN in the transnational enforcement of Consumer Law and Competition Law as well as the tasks of the ESOs in the processes managed by the International Standardization Organization (“ISO”). The goals of this research consist in framing the emerging European experience in ‘network governance’ within the wider theoretical framework provided for by the “network theory”.;158945,6;158945,6;FP7-PEOPLE-2009-IEF;/MC-IEF;UNIVERSITE PARIS II PANTHEON ASSAS;FR;;;"/SCI;/EDU;/ITT";0;1;0;0;0;1 95940;244618;IMPACT;ONG;FP7-SSH;SSH-2009-2.1.3.;FP7;Impact Measurement and Performance Analysis of CSR;2010-03-01;2013-07-31;http://www.csr-impact.eu;Corporate Social Responsibility (CSR) assumes greater practical significance and political relevance in the EU. A central concern is the extent to which CSR delivers benefits for economies, societies and the environment, providing a business contribution to the EU’s policies for growth, competitiveness, better jobs (Lisbon Strategy) and sustainable development (Gothenburg strategy). By contrast there is little empirical evidence on the impacts of CSR practices on company performance and the wider economy, or the social and environmental fabric of Europe, its nations and regions. There are no widely applied tools and methods that provide valid and representative assessments of the impacts of CSR. The IMPACT project addresses these gaps in knowledge. The project uses a common conceptual framework to develop and apply tools that enable assessment and comparison of CSR impacts – at micro (company), meso (sectoral and regional) and macro levels (nations states and EU). Indicators will be developed to assess the contribution of CSR impacts on EU policy objectives, for growth, competitiveness (including innovation), quality of jobs and environmental sustainability. A large-scale inter- and transdisciplinary empirical investigation will be carried out using four complementary methods: econometric analysis, company case studies, an analysis of different company and industrial networks and a Delphi study. All studies focus on five sectors important across the EU-27. The results will be synthesised and triangulated with each other. A foresight study will estimate ex ante future impacts of CSR. Recommendations will be addressed to policy-makers, especially those dealing with the CSR and the Lisbon and Gothenburg Strategies, also business leaders, CSR practitioners, civil society and the research and education community. Outputs include a handbook on CSR impact assessment tools, a comprehensive description of European CSR impacts to date and policy recommendations.;3328791,98;2599974;FP7-SSH-2009-A;/CP-FP;OEKO-INSTITUT E.V. - INSTITUT FUER ANGEWANDTE OEKOLOGIE;DE;"STICHTING CENTERDATA;CEU Uzleti Kar Kozhasznu Nonprofit Korlatolt Felelossegu Tarsasag;ABIS - THE ACADEMY OF BUSINESS IN SOCIETY;KOZEP-EUROPAI EGYETEM;AALTO KORKEAKOULUSAATIO SR;ZENTRUM FUER EUROPAEISCHE WIRTSCHAFTSFORSCHUNG GmbH;INSTITUT FUR SOZIAL OKOLOGISCHE FORSCHUNG GMBH;COPENHAGEN BUSINESS SCHOOL;UNIVERSIDAD DE NAVARRA;THE UNIVERSITY OF NOTTINGHAM;STICHTING KATHOLIEKE UNIVERSITEIT BRABANT;WIRTSCHAFTSUNIVERSITAT WIEN;VLERICK BUSINESS SCHOOL;KATHOLIEKE UNIVERSITEIT LEUVEN;MIP - CONSORZIO PER L'INNOVAZIONE NELLA GESTIONE DELLE IMPRESE E DELLA PUBBLICA AMMINISTRAZIONE;INSTITUT EUROPEEN D ADMINISTRATION DES AFFAIRES;Akademia Leona Kozminskiego";"NL;HU;BE;FI;DE;DK;ES;UK;AT;IT;FR;PL";"/SOC;/BUS";0;1;0;0;0;1 97005;249488;ENTCHILD;ONG;FP7-IDEAS-ERC;ERC-AG-SH2;FP7;The Entertainization of Childhood: An Etiology of Risks and Opportunities;2010-12-01;2016-08-31;;Never before has media entertainment been so abundantly accessible to children. In this project, I propose an entirely new theoretical model to understand entertainment processing and effects. The model enables us to simultaneously investigate: (a) how and why certain types of media entertainment may influence certain children, (b) which children are particularly susceptible to positive, which to negative, and which to both positive and negative entertainment effects, and (c) how children s social environment can maximize positive and minimize negative entertainment effects on children. The project involves a longitudinal panel study among 900 Dutch families. To measure the variables in the model, we will use some well-established survey instruments and neuropsychological tests. We will also employ two less conventional methods (coded media-use diaries and experience sampling methods) that may enhance serendipity in the development of our theory-advancing insights. We will use state-of-the art data-analytic techniques (e.g., multi-level and latent-growth curve modelling) to analyse the data. Although adventurous, this transdisciplinary project, the first in its kind, has great theoretical significance. If the assumptions of my model are supported, it may lead to a fundamental re-evaluation of earlier media-effects theories and research on children. The project will also have tremendous social relevance, not only for parents, but also for programme makers, educators, and the society as a whole. After all, only if we truly understand why, how, and which children are influenced by certain types of media entertainment, are we able to adequately target prevention and intervention strategies at these children.;2500000;2500000;ERC-2009-AdG;/ERC-AG;UNIVERSITEIT VAN AMSTERDAM;NL;;;/SOC;0;1;0;0;0;1 104681;306708;FEMTOELEC;ONG;FP7-IDEAS-ERC;ERC-SG-PE2;FP7;Innovative Femtosecond laser-plasma based electron source for studying ultrafast structural dynamics;2013-01-01;2017-12-31;;"How do atoms move in a solid? How long does it take for a phase transition to occur or for a molecule to change its configuration? These are some of the fundamental questions that the field of ultrafast science asks and attempts to answer. Understanding these ultrafast processes in complex matter at the atomic scale requires advanced sources of radiation: X-rays or electrons with sub-angstrom wavelength and femtosecond duration. In the past decade, such sources have become available, allowing scientists to obtain a first glimpse into the ultrafast world, with the direct observation of atomic motion or structural changes in matter. Until now however, the time resolution has not allowed us to study the fastest processes and has limited our window of observation to processes slower than 100 femtoseconds. To overcome this limitation, this proposal introduces a new method based on laser-plasma interaction for producing an electron source with shorter duration. The project will explore laser-plasma interaction in a new regime: low energy, high-repetition, few-cycle laser pulses interacting with a plasma for producing femtosecond electron bunches with parameters relevant for probing matter with electron diffraction. It will take advantage of the very high accelerating gradients that plasmas can sustain for accelerating electrons to relativistic energies in micrometer lengths. This novel electron source will be implemented in diffraction experiments for probing structural dynamics in condensed matter with angstrom spatial resolution and unprecedented time resolution. This table-top innovative electron source has the potential to overcome the limitations of current ultrafast electron diffraction and could offer new insights for transdisciplinary applications in condensed matter physics, chemistry and biology.";1491350;1491350;ERC-2012-StG_20111012;/ERC-SG;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FR;;;"/PSE;/SCI";0;1;0;0;0;1 94028;244170;PEGASO;ONG;FP7-ENVIRONMENT;ENV.2009.2.2.1.4;FP7;People for Ecosystem Based Governance in Assessing Sustainable Development of Ocean and Coast;2010-02-01;2014-01-31;;"Many efforts have been deployed for developing Integrated Coastal Zone Management (ICZM) in the Mediterranean and the Black Sea. Both basins have, and continue to suffer severe environmental degradation. In many areas this has led to unsustainable trends, which have impacted, on economic activities and human well-being. An important progress has been made with the launch of the ICZM Protocol for the Mediterranean Sea in January 2008. The ICZM Protocol offers, for the first time in the Mediterranean, an opportunity to work in a new way, and a model that can be used as a basis for solving similar problems elsewhere, such as in the Back Sea. The aim of PEGASO is to build on existing capacities and develop common novel approaches to support integrated policies for the coastal, marine and maritime realms of the Mediterranean and Black Sea Basins in ways that are consistent with and relevant to the implementation of the ICZM Protocol for the Mediterranean. PEGASO will use the model of the existing ICZM Protocol for the Mediterranean and adjust it to the needs of the Black Sea through three innovative actions: - Constructing an ICZM governance platform as a bridge between scientist and end-user communities, going far beyond a conventional bridging. The building of a shared scientific and end users platform is at the heart of our proposal linked with new models of governance. -Refining and further developing efficient and easy to use tools for making sustainability assessments in the coastal zone (indicators, accounting methods and models, scenarios, socio-economic valuations, etc). They will be tested and validated in 10 sites (CASES) and by the ICZM Platform, using a multi-scale approach for integrated regional assessment. -Implementing a Spatial Data Infrastructure (SDI), following INSPIRE Directive, to organize local geonodes and standardize spatial data to support information sharing on an interactive visor, to make it available to the ICZM Platform, and to disseminate all results of the project to all interested parties and beyond. -Enhancing regional networks of scientists and stakeholders in ICPC countries, supported by capacity building, to implement the PEGASO tools and lessons learned, to assess the state and trends for coast and sea in both basins, identifying present and future main threats agreeing on responses to be done at different scales in an integrated approach, including transdisciplinary and transbondary long-term collaborations.";8827935,97;6999004,56;FP7-ENV-2009-1;/CP-IP-SICA;UNIVERSITAT AUTONOMA DE BARCELONA;ES;"ACRI ETUDES ET CONSEIL;UNIVERSIDAD PABLO DE OLAVIDE;MARINE HYDROPHYSICAL INSTITUTE - UKRAINIAN NATIONAL ACADEMY OF SCIENCES;INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE DELTA DUNARII;UNIVERSITE DE GENEVE;FONDATION TOUR DU VALAT;UNIVERSITE MOHAMMED V DE RABAT;UNITED NATIONS EDUCATIONAL, SCIENTIFIC AND CULTURAL ORGANIZATION -UNESCO;HELLENIC CENTRE FOR MARINE RESEARCH;UNIVERSITY OF BALAMAND;National Institute of Oceanography and Fisheries;THE COMMISSION ON THE PROTECTION OFTHE BLACK SEA AGAINST POLLUTION;UNION INTERNATIONALE POUR LA CONSERVATION DE LA NATURE ET DE SES RESSOURCES;UNIVERSITA CA' FOSCARI VENEZIA;PLAN BLEU POUR L'ENVIRONNEMENT ET LE DEVELOPPEMENT EN MEDITERRANNEE;National Authority for Remote Sensing and Space Sciences;INSTITUT FRANCAIS DE RECHERCHE POUR L'EXPLOITATION DE LA MER;THE UNIVERSITY OF NOTTINGHAM;University Mohammed V-Agdal;Association de Réflexion, d'Echanges et d'Actions pour l'Environnement et le Développement;AKDENIZ KIYI VAKFI;VLAAMS INSTITUUT VOOR DE ZEE VZW;Priority Actions Programme Regional Activity Centre;JRC -JOINT RESEARCH CENTRE- EUROPEAN COMMISSION";"MA;ES;UA;RO;CH;FR;EL;LB;EG;TR;IT;UK;DZ;BE;HR";"/WAT;/ENV";0;1;0;0;0;1 90609;236628;ILISENSE;ONG;FP7-PEOPLE;FP7-PEOPLE-IEF-2008;FP7;Ionic Liquids and Carbon Nanotubes for Sensors and Separations;2009-08-01;2011-07-31;;This project aims at exploring novel materials and their composites for significantly enhancing the performance of dedicated gas sensors as well as separation barriers. The focus will be on two emerging materials, namely carbon nanotubes and room-temperature ionic liquids, as well as composites consisting of both, with the aim of creating highly versatile and flexible affinity interfaces that exhibit drastically improved physico-chemical properties compared to conventional materials. During this truly multidisciplinary project, these materials and their composites are to be explored on one hand in combination with advanced gas sensor systems, in order to determine both the potential, possible windows of operation as well as the respective limitations. On the other hand, it is deliberately envisaged to study these materials and the respective composites for application in an apparently diverse area, namely gas/vapour separation barriers. The underlying aim of this approach is that both successful gas sensing and gas/vapour separation require high selectivities to target solutes, and transport phenomena naturally occurring in the latter can be a limiting factor in the former, although often neglected. This project will therefore exploit the application of carbon nanotubes and room-temperature ionic liquids, as well as their composites, in a strongly transdisciplinary manner in order to foster knowledge transfer between two of the priority areas of the NMP-programme for the benefit of significant advances in both.;;209799,48;FP7-PEOPLE-IEF-2008;/MC-IEF;UNIVERSITAT ROVIRA I VIRGILI;ES;;;"/SCI;/EMP";0;1;0;0;0;1 91988;220550;INTER-COM;ONG;FP7-PEOPLE;PEOPLE-2007-2-1.IEF;FP7;Integral leadership and communication in non-profit organisations;2009-09-23;2011-09-22;;Leadership and communication process become increasingly important in organisations. Specific developments like budget cutting, deregulation, marketisation or privatisation of non-profit services and changing public policies exert an increasing influence particularly on non-profit organisations. A large amount of studies has shown the impact of both leading and communicating in this context. However there exists no comprehensive integral model and corresponding empirical research on the linkage between leadership and communication in non-profit organisations. The objective of this project is to construct such a model and to investigate empirically the relationship between leadership and communication in non-profit organisations in Germany and Switzerland. To achieve this objective, the project will: (1) start from existing theories with an inter- and transdisciplinary approach, developing an integral framework and research design as well methodology, rendering describable key variables, and moderating factors as well as problem areas and barriers of leadership and communication practices. (2) deduce hypotheses from theoretical propositions and the integral framework, considering subjective, inter-subjective and objective levels, that are covering specifically the interconnected processes of intentional, emotional and behavioural as well as socio-cultural and structural domains of leadership and communication. (3) test the hypotheses and validity of the integral model empirically in concrete context of German and Swiss non-profit organisation, including a comparative analysis. (4) derive theoretical and practical implications as well as societal relevant policies for an effective leadership and communication as well as corresponding organisational learning. The implications include also suggestions for an European oriented leadership and communication development in non-profit organisations.;169998,76;169998,76;FP7-PEOPLE-2007-2-1-IEF;/MC-IEF;UNIVERSITA DELLA SVIZZERA ITALIANA;CH;;;"/SCI;/EDU";0;1;0;0;0;1 109885;605867;BATWOMAN;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-ITN;FP7;Basic Acoustics Training - & Workprogram On Methodologies for Acoustics - Network;2013-09-01;2017-08-31;http://www.batwoman.eu/;"The BATWOMAN ITN aims at structuring research training in basic and advanced acoustics and setting up a work program on methodologies for acoustics for skills development in a highly diverse research field offering multiple career options. The consortium consists of renowned public and private partners from musical acoustics, room acoustics and automotive acoustics who will merge their existing knowledge, extend it jointly and complement it with insights of recent sound perception research. This will exploit existing synergies and overcome obvious fragmentation in research, methodology and basic as well as advanced acoustics training. Providing interdisciplinary training and joining or exchanging methodology in research, is expected to have a strong impact on the skills of trained researchers as far as sound design capabilities, modelling accuracy, efficiency and applicable frequency range is concerned. Adding the understanding of human auditory perception will help to tackle the hard problem of sound quality parameters and to better understand stimulating effects on well-being and cognition of people exposed to sound, but also harmful effects, like annoyance or even deteriorating cognitive performance. The ITN will provide interdisciplinary and intersectoral research training for excellence. It will structure existing PhD-level training in acoustics setting up European curricula with compatible and recognised courses offered by Universities and private enterprises. Simultaneously it will push the state of the art in vibro-acoustic modelling and in interdisciplinary design optimisation by initiating a joint research effort increasing critical mass. The complementary structure of the network will make it not to break apart after the ITN project period. It is rather expected that the methodologies used to analyse, design and optimise transport vehicles, rooms and musical instruments will grow together and will be further developed in an interdisciplinary joint effort.";3811027,76;3811027,76;FP7-PEOPLE-2013-ITN;/MC-ITN;Kompetenzzentrum - Das Virtuelle Fahrzeug, Forschungsgesellschaft mbH;AT;"UNIVERSITAT FUR MUSIK UND DARSTELLENDE KUNST WIEN;HOCHSCHULE FUER MUSIK DETMOLD;SIEMENS INDUSTRY SOFTWARE NV;Ecole Nationale Superieure de Techniques Avancees;AVL LIST GMBH;PHILIPS ELECTRONICS NEDERLAND B.V.;MULLER-BBM GMBH;TECHNISCHE UNIVERSITEIT EINDHOVEN;KATHOLIEKE UNIVERSITEIT LEUVEN;THE UNIVERSITY OF EDINBURGH";"AT;DE;BE;FR;NL;UK";/LIF;1;0;0;4;0;0 187786;623645;GLASSTECH2013;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IEF;FP7;Continuity and change in the emergence of the Hellenistic Glass industry in Greece;2014-10-01;2016-09-30;;"This innovative interdisciplinary investigation of ancient Greek glass dating to between 1100BC and 300BC is designed to transform the knowledge base for the material so as to enhance in fundamental ways archaeological, art historical, socio-economic and technological interpretations. It will also simplify and prioritise the planning of appropriate conservation strategies for the glass. It will be the first such study to define the provenance of glass raw materials and glass within the region of Greece. A further research objective is to identify the locations where primary production of Greek glass occurred, clarifying the economic dynamics governing Hellenistic glass production and trade and enhancing the knowledge of the ancient Greek economy. The project will allow Dr. Oikonomou to work in a leading-edge interdisciplinary environment that will give him the best possible opportunity to move to other research and teaching institutions in Europe. He will be trained in a range of transferable skills including sample selection and preparation, in the use of innovative, advanced and state-of-the art chemical, isotopic and micro-structural scientific techniques and a range of interpretative interdisciplinary and statistical methods. The fellowship will allow him to enhance dramatically his knowledge base. The research project will provide a powerful contribution to the European Research Area and will generate other research that will contribute strongly to the study and conservation of European Heritage after the end of the fellowship. The interdisciplinary team that will train Dr. Oikonomou is formed from international experts in their fields, both in the University and industrial sectors. The support infrastructure at Nottingham University is geared to provide clear and groundbreaking opportunities for postdoctoral fellows. Outreach activities will make fundamental contributions including to secondary schools, the museum sector and a structured web page.";221606,4;221606,4;FP7-PEOPLE-2013-IEF;/MC-IEF;THE UNIVERSITY OF NOTTINGHAM;UK;;;;1;0;0;4;0;0 187870;624711;INTERNET PRIVACY;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IEF;FP7;The Privacy Policies of Internet Intermediaries: High-tech Responsibility in the Multi-stakeholder Nexus;2014-12-01;2016-11-30;;"This project advances and interrelates two new conceptual insights – i.e. the ‘high-tech responsibility’ and ‘multi-stakeholder nexus’ concepts – and uses these concepts to conduct an empirical analysis of the privacy policies, and broader political context, of the four internet intermediaries (IIs) that dominate the European search engine and social media market: i.e. Facebook, Google, Microsoft and Yahoo! The project employs inductive top down theorizing to construct the two concepts that provide a ‘sensegiving’ function to the project’s problem domain, and uses archival (internet) research, network analysis, and automated semantic network analysis, to empirically analyse the project’s problem domain. The project is at the cutting-edge of research in corporate social responsibility (CSR)/organization studies and internet governance/privacy, and addresses a problem domain of pressing importance to European Union states and citizens. The project contributes to Europe’s research excellence by strengthening ties between leading European scholars and research centres; by contributing to the development of a new field of interdisciplinary scholarship of broad societal importance; and by providing European researchers with ‘first mover’ advantage in this interdisciplinary field. The project will support the researcher’s career development through significantly advancing his long-term career plan to elaborate political understandings of CSR and multi-national corporations (MNCs). It will develop his research approach/methodology, and advance his interdisciplinary knowledge of internet governance/privacy and MNCs. Copenhagen Business School (CBS) – the host institution – has interdisciplinary expertise in CSR/organization studies, internet governance/privacy, and communicative research methods. Accordingly, and given CBS’s ‘business in society’ research strategy more generally, CBS provides the perfect work environment for the project.";308587,8;308587,8;FP7-PEOPLE-2013-IEF;/MC-IEF;COPENHAGEN BUSINESS SCHOOL;DK;;;;1;0;0;4;0;0 185634;616510;ENLIFE;ONG;FP7-IDEAS-ERC;ERC-CG-2013-SH2;FP7;Engineering life: ideas, practices and promises;2014-09-01;2019-02-28;;"The emerging field of synthetic biology promises to engineer the living world. This is potentially extremely contentious, so scholars from the social sciences and humanities have been incorporated into synthetic biology research programmes from the outset. The ENLIFE project’s distinctive contribution will be to study both the engineering of biology and the role of social scientists within this. Its two objectives are: to investigate the movement of ideas, practices and promises from engineering into the life sciences, and to examine the ways in which social scientists and other groups are being mobilised as part of this endeavour. We will carry out novel social scientific research into the engineering of living things, by collecting a rich body of empirical data. This will involve semi-structured qualitative interviews, participant observation at conferences, and ethnographic research in synthetic biology laboratories that are attempting to make biology easier to engineer. We will simultaneously address the interdisciplinary entanglements that arise in all these contexts, which involve scientists, engineers, social scientists, philosophers, lawyers and sometimes even artists and designers. We will also run four experimental interdisciplinary workshops, where we will explore the possibility of producing new knowledge together, across disciplinary divides. The project aims to provide a critical, empirically grounded analysis of a field that promises to drive the next industrial revolution and is currently the target of high levels of investment across the globe. It will also provide insights into the engineering imagination, how it is applied to living things, and how it is challenged and expanded in interdisciplinary interactions. The study of these interactions will build on our understanding of the role of the social sciences in interdisciplinary collaborations, and contribute to pressing debates about the future of Science and Technology Studies.";1559389;1559389;ERC-2013-CoG;/ERC-CG;THE UNIVERSITY OF EDINBURGH;UK;Arizona Board of Regents;US;"/SCI;/SOC";1;0;0;4;0;0 111453;336932;RATIMED;ONG;FP7-IDEAS-ERC;ERC-SG-SH2;FP7;Re-Assembling Tibetan Medicine: The formation of a transnational Sowa Rigpa industry in contemporary India, China, Mongolia and Bhutan;2014-04-01;2019-03-31;;"'“Traditional medicine” has recently emerged from a highly marginalized position in many parts of the world to become a rapidly expanding and highly innovative multi-billion dollar global industry. However, despite growing academic, economic and public interest in the “traditional” pharmaceutical industry, we know little about its larger dynamics, shape, and wider socio-economic and public health implications. The proposed 5-year interdisciplinary study of the emergent transnational Tibetan medicine (or “Sowa Rigpa”) industry in India, China, Mongolia and Bhutan aims to fill this gap. The Sowa Rigpa industry, in which Tibetan medicine is transformed into a mass-produced commodity for domestic and international markets, is a particularly illustrative and timely case of 'traditional' medicine's development. It is illustrative because it reflects the dynamics of the traditional pharma industry at large, and it is timely because Tibetan medicine’s industrialization and pharmaceuticalization has only begun during the last decade, enabling this study to investigate its formation in real time. Introducing the concept of the pharmaceutical assemblage,the proposed project will break new ground by being the first comprehensive, large-scale, interdisciplinary study of Sowa Rigpa in a transnational context. It will apply an innovative interdisciplinary approach to generate a 'big picture' of this industry and unprecedented insights into the global traditional pharma market, which despite its growing relevance and popularity remains poorly understood. This project will be based at the AAS’s Institute for Social Anthropology, carried out by an international team of 4 post-doctoral researchers, and involve 54 months of multi-sited field research. Besides numerous publications, 2 international workshops and 1 conference will be organized to present the results. While interdisciplinary, the research will be grounded in the field of medical and socio-cultural anthropology.'";1461138,8;1461138,8;ERC-2013-StG;/ERC-SG;OESTERREICHISCHE AKADEMIE DER WISSENSCHAFTEN;AT;;;/SOC;1;0;0;4;0;0 108310;330876;FORCONEPAL;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IOF;FP7;Forest Resource Conservation in Nepal;2014-03-01;2017-02-28;;Managing natural resources to sustain human livelihood needs while minimizing the loss of biodiversity and ecosystem services is, arguably, the greatest challenge facing our generation. Top-down approaches to preserve natural resources, e.g. protected areas, have had limited success in integrating local social needs with natural resource management. Local communities use and manage more than 10% of the world’s forests, which are key biomes for biodiversity. Governments and conservation initiatives are increasingly recognizing the role of local communities in natural resource conservation but there is little evidence of how local community needs interact with ecological processes. This fellowship will focus on community-managed forests and investigate, for the first time, how long-term environmental outcomes influence - and are influenced by - community management practices. To address this issue, the candidate fellow Dr. Johan Oldekop, will focus on a series of community-managed forests in Nepal and lead an interdisciplinary collaboration between Dr. Mark Whittingham at Newcastle University (UK), and Prof. Arun Agrawal and the International Forestry Resources and Institutions Programme (IFRI) at the University of Michigan (USA). Research outcomes will be highly relevant for forest management policies globally (including community management initiatives in European forests). By leading a high-impact interdisciplinary and policy relevant research programme, Dr. Oldekop will master a unique set of complementary skills and position himself at the lead of interdisciplinary socio-ecological research. Becoming one of Europe’s first uniquely trained interdisciplinary conservation scientists will allow Dr. Oldekop to establish new international collaborations and significantly expand European research excellence and competitiveness.;294693;294693;FP7-PEOPLE-2012-IOF;/MC-IOF;THE UNIVERSITY OF SHEFFIELD;UK;UNIVERSITY OF NEWCASTLE UPON TYNE;UK;/LIF;1;0;0;4;0;0 103926;302530;Ubicom Mental Health;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IOF;FP7;Ubiquitous mental health support systems for managing long-term mental health illness;2012-07-15;2015-07-14;;This fellowship is a significant step in Dr. Matthews’ career, bringing him back into full-time research leading an innovative project in e-mental health between Professor Gay’s lab in Cornell University and Dr. Doherty’s in Trinity College Dublin. The project will develop technologies to support individuals with bipolar disorder, an extremely challenging illness which has significant negative impacts on individuals, their families and societies. This project extends the EU’s E-Health initiative by applying ICT to the improvement of mental health.The candidate has an interdisciplinary background and his work to date in ubiquitous support systems provides a strong foundation to carry out the proposal and push this research area forward. Throughout Dr. Matthews’ career he has sought to identify areas for further personal development. His training objectives include establishing a full- time academic career, further developing interdisciplinary competencies and gaining commercialisation expertise. These goals will be met through formal courses and applied research. This fellowship represents Dr. Matthews’ 1st post-doctoral research position. At Cornell University, he will be able to work with world-class researchers in healthcare, social networks and bipolar disorder. Cornell and Trinity are among the best universities in the world and will provide the necessary materials, expertise and excellent support services to carry out this project. As an interdisciplinary project in a highly sensitive area, it will need experts in each field, all of whom have committed to this project.This fellowship is a vital step in establishing Dr. Matthews as a leading researcher in an emerging and increasingly important field. His ambition is to establish an interdisciplinary research centre for ICT & mental health. There is an opportunity to establish Europe as a world leader in this emerging area.;279149,7;279149,7;FP7-PEOPLE-2011-IOF;/MC-IOF;THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN;IE;;;/SCI;1;0;0;4;0;0 111267;608959;ImPuLSe;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-COFUND;FP7;CRG International Postdoctoral Fellowship Programme in Life Sciences;2014-01-01;2018-12-31;;"The proposed “CRG International Postdoctoral Fellowship Programme in Life Sciences” (ImPuLSe) builds on the existing Fellowship Programme “International Interdisciplinary Postdoctoral Programme (InterPod) running from 2010 to 2014, co-funded by the FP7 COFUND scheme. ImPuLSe aims at enabling outstanding junior scientists of all nationalities to develop a competitive research project in life sciences at the CRG, thus promoting the transnational mobility and career perspectives of young scientists in Europe. The CRG is an international biomedical research institute of excellence with strengths in Systems Biology, Cell Biology, Stem Cells and Cancer, Epigenetics, Reprogramming, Genetic Diseases and Bioinformatics. As a unique international research institute (76% of non-Spanish research staff), it draws on the organisational model similar to European Molecular Biology Laboratory (EMBL) and holds a strategic partnership with them. The proposed 5-year Programme offers a total of 12 fellowships to be announced in 2 competitive calls. The Programme fellows will benefit from an exciting international scientific environment and an integrated training programme, including access to state of the art infrastructure, mentoring, lectures and seminars, specialised scientific and technological courses, complementary skills training and career development activities, postdoctoral symposia and retreats, as well as social activities. In comparison to the previous Programme, the ImPuLSe Programme offers improved features (e.g. higher number of fellowships and participation of Sanofi as an industrial partner); while keeping the emphasis on interdisciplinarity, peer-review, as an added value. ImPuLSe will contribute to providing the highest quality scientific training, and improving the mobility of young scientists in Europe for a successful career in science, offering interdisciplinary, integrated training and attractive employment conditions.";2610108;1044043,2;FP7-PEOPLE-2013-COFUND;/MC-COFUND;FUNDACIO CENTRE DE REGULACIO GENOMICA;ES;;;/LIF;1;0;0;3;0;0 93573;244255;WASSERMED;ONG;FP7-ENVIRONMENT;ENV.2009.1.1.5.2;FP7;Water Availability and Security in Southern EuRope and the Mediterranean;2010-01-01;2013-03-31;;"The WASSERMed project will analyse, in a multi-disciplinary way, ongoing and future climate induced changes in hydrological budgets and extremes in southern Europe, North Africa and the Middle East under the frame of threats to national and human security. A climatic and hydrological component directly addresses the reduction of uncertainty and quantification of risk. This component will provide an interface to other climatologic projects and models, producing climate change scenarios for the Mediterranean and Southern Europe, with special emphasis on precipitation. Five case studies will be considered: 1) Syros Island (Greece), 2) Sardinia Island (Italy), 3) Merguellil watershed (Tunisia), 4) Jordan river basin, and 5) the Nile River system (Egypt). The case studies are illustrative and represent situations which deserve special attention, due to their relevance to national and human security. Furthermore, impacts on key strategic sectors, such as agriculture and tourism, will be considered, as well as macroeconomic implications of water availability in terms of regional income, consumption, investment, trade flows, industrial structure and competitiveness. WASSERMed is an interdisciplinary project, which overall aims at all three targets of the call, through the integration of climate change scenarios, holistic water system modelling and interdisciplinary impact assessment, with three main contributions: a) Integration of climate change scenarios, holistic water system modelling. This provides results for reduction of uncertainties of climate change impacts on hydrology in the identified regions; b) Interdisciplinary approach, coupling macroeconomic implications and technical indicators. This provides a better assessment of climate effects to water resources, water uses and expected security risks; c) Proposal of specific adaptation measures for key sectors of the Mediterranean economy. This provides better basis for achieving water security.";3669943,27;2933973,3;FP7-ENV-2009-1;/CP-FP-SICA;FONDAZIONE CENTRO EURO-MEDITERRANEO SUI CAMBIAMENTI CLIMATICI;IT;"THE UNIVERSITY OF EXETER;NATIONAL TECHNICAL UNIVERSITY OF ATHENS - NTUA;MINISTRY OF WATER RESOURCES AND IRRIGATION;POTSDAM INSTITUT FUER KLIMAFOLGENFORSCHUNG;UNIVERSITY OF JORDAN;NATIONAL CENTRE FOR AGRICULTURAL RESEARCH AND EXTENSION, MINISTRY OF AGRICULTURE;CENTRO INTERNAZIONALE DI ALTISTUDI AGRONOMICI MEDITERRANEI;CLU srl;INSTITUT DE RECHERCHE POUR LE DEVELOPPEMENT;UNIVERSIDAD POLITECNICA DE MADRID;Institut National Agronomique de Tunisie";"UK;EL;EG;DE;JO;IT;FR;ES;TN";"/WAT;/ENV;/SEC";1;0;0;3;0;0 108622;330354;AGE-FRIENDLY;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IEF;FP7;Promoting Active Ageing: Developing Age-Friendly Cities;2013-10-01;2015-09-30;;"Need for the research: Although the issues raised by the 'age-friendly city' movement are well-understood at the level of the World Health Organisation and European Union, awareness within relevant academic disciplines is still limited. This project will fill a major gap in the literature by providing a substantial research base for assisting the development of age-friendly cities. Host and researcher: The proposed fellowship is a collaboration between a world-class scientist working at the University of Manchester, UK (Prof. Chris Phillipson) and an ambitious post-doctoral researcher currently based in Belgium (Dr. Tine Buffel). The research fellow, Dr. Tine Buffel (Vrije Universiteit Brussel), is one of Belgium’s most accomplished young researchers in the field of ageing. The host, Prof. Chris Phillipson has been a key figure in the development of social gerontology, and is one of the world’s leading researchers with expertise in population ageing and urbanization. Interdisciplinary nature: A key objective of the fellowship includes the development of an interdisciplinary approach to studying age-friendly environments. An interdisciplinary project team and advisory board will be formed to support and develop the career progression of the fellow. Both will comprise leading international researchers working across a range of disciplines (including social geography, psychology, environmental gerontology, urban design, architecture, and epidemiology) relevant to developing age-friendly cities. Benefits to Europe: Promote healthy and active ageing in Europe; contribute to European excellence regarding research on population ageing; advance Europe’s competitiveness by involving older people in research and innovation; provide outreach activities which will be beneficial to the development of the European policy agenda on Active Ageing.";231283,2;231283,2;FP7-PEOPLE-2012-IEF;/MC-IEF;THE UNIVERSITY OF MANCHESTER;UK;;;/SCI;1;0;0;3;0;0 88962;227430;VIN;ONG;FP7-IDEAS-ERC;ERC-AG-PE4;FP7;Video-rate Scanning Probe Microscopy Imaging of Nanostructures on Surfaces;2008-12-01;2013-11-30;;The goal of this ERC proposal VIN is to develop the next generation of scanning probe microscopes (SPMs) The microscopes will set new standards in the field through their ability to acquire images at video-rate frequency, while retaining high (atomic) resolution capability. This new instrumental platform will be implemented both under ultra-high vacuum conditions, in a high-pressure gas cell, and under liquid-phase conditions. It will be utilized to create and explore novel research avenues for the study of physical, chemical, and biological surface processes at the single-atom/molecule level with the highest possible spatial and temporal resolution. In particular I will study dynamic phenomena in surface nanostructures, focusing on three mutually synergetic and interdisciplinary priority areas: i) Catalytic reactivity of nanostructures, ii) Self-organisation of organic molecules at surfaces, iii) Biomolecular structures, processes and interactions under physiological conditions. The adsorption, diffusion and interaction of molecules are the basic steps involved in reactions at surfaces. All of them are dynamic processes, where high temporal resolution can provide new groundbreaking insight into e.g. the mechanisms underlying catalysis. Video-rate SPMs will also facilitate investigations of the kinetic aspects of molecular self- organisation at surfaces such as diffusion, intra-molecular conformational dynamics, nucleation and growth of structures. The effort will build upon the world-leading expertise in design, construction and use of SPMs in my research group at the Interdisciplinary Nanoscience Center (iNANO) and the Department of Physics and Astronomy, University of Aarhus, Denmark. To achieve the ambitious research goals, I will bring together an interdisciplinary team of highly talented younger scientists.;1324983;1324983;ERC-2008-AdG;/ERC-AG;AARHUS UNIVERSITET;DK;;;/PSE;1;0;0;3;0;0 104382;287382;PIMMS;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-ITN;FP7;Proton Ionization Molecular Mass Spectrometry;2012-06-01;2016-05-31;;'The need for quantitative and fast identification of trace gaseous compounds in complex chemical matrices continuously pushes the limits of analytical chemistry in many areas of relevance to the EU, including food, health, the environment, and security. A relatively new broad-based and rapidly growing analytical technique, proton transfer reaction mass spectrometry (PTR-MS), combines excellent chemical specification with ultra high detection sensitivity in real-time, but is only partially exploited owing to the lack of a focused research programme in terms of its scientific fundamentals and applications, and owing to a lack of an intersectoral and interdisciplinary based forum for the exchange of ideas and best practice to further develop PTR-MS. The demand for PTR-MS is outstripping the supply of highly qualified chemists who cannot only use the technology, but who also have a broad background in analytical chemistry, and are capable of leading multidisciplinary research/commercial activities. There is an urgent need within Europe for the harmonized training of ESRs in analytical chemistry within many sectors and across many disparate scientific disciplines and applications. The overall goal of this multidisciplinary and interdisciplinary ITN is to train the next generation of analytical scientists in the skills necessary for the development and use of PTR-MS and other analytical technologies (including GC-MS, SIFT-MS and IMS) for the detection of trace gaseous compounds. Our vision is to enhance our understanding of the crucial role these chemicals play in many complex chemical environments and the underpinning science needed to develop techniques to address major analytical challenges. The network is intersectoral in nature combining commercial (both manufacturers and “end-users”), governmental and academic concerns using a range of state-of-the-art analytical techniques, to address a number of topical analytical issues in an interdisciplinary cooperative.';4134042;4134042;FP7-PEOPLE-2011-ITN;/MC-ITN;THE UNIVERSITY OF BIRMINGHAM;UK;"FORSCHUNGSZENTRUM JULICH GMBH;HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH;UNIVERSITA DEGLI STUDI DI NAPOLI FEDERICO II;FONDAZIONE EDMUND MACH;UNIVERSITAET ROSTOCK;UNIVERSITAET INNSBRUCK;THE OPEN UNIVERSITY;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;ZURCHER HOCHSCHULE FUR ANGEWANDTE WISSENSCHAFTEN;IONICON ANALYTIK GMBH;STICHTING WAGENINGEN RESEARCH";"DE;IT;AT;UK;FR;CH;NL";"/LIF;/SCI";1;0;0;3;0;0 105380;316889;FLOWTRANS;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-ITN;FP7;Flow in Transforming Porous Media;2013-01-01;2016-12-31;;The FlowTrans Initial Training Network is a unique environment for career development, built on joint challenges of Industry and University partners in a newly emerging supra-disciplinary field, spanning from Physics to Earth Sciences and aiming to understand Flow in Transforming Porous Media. Training will be hosted by 8 Universities in synergy with 2 full and 4 associated industry partners with the objective of delivering highly-trained mobile researchers to the European market. The objective of FlowTrans is the creation of a unique research training environment and a new inter-sectoral supra-interdisciplinary field to de-fragment European knowledge and combine industry and universities to harness understanding of basic scientific questions for tackling future challenges in Exploration of Geological Resources. Our research training objectives focus on teaching ESRs and ERs the necessary interdisciplinary skills needed to study Flow in Transforming Porous Media. The characterization and the understanding of flow of fluids within rocks and granular media has become an ever-increasing problem in Earth Sciences, Physics, and in many industrial applications, including CO2 sequestration, hydrocarbon migration, ore deposit development, and radioactive waste disposal. One of the main problems is the understanding of flows in transforming porous media (PM), where the rocks and fluid pathways evolve spatially and temporally, for example due to chemical interactions with the flow, or due to compaction of the solid matrix. We propose to study the feedback mechanisms and their impact on the porous media through an interdisciplinary approach between Earth Scientists and Physicists. State of the art analytical and experimental methods will be used on natural systems and rock analogues, and will be complemented by multi-scale dynamical simulations, to develop new basic understanding and new methods that can be directly used in industrial applications.;4159270,94;4159270,94;FP7-PEOPLE-2012-ITN;/MC-ITN;UNIVERSITY OF GLASGOW;UK;"UNIWERSYTET WARSZAWSKI;KOBENHAVNS UNIVERSITET;MAGNITUDE SAS;UNIVERSITE JOSEPH FOURIER GRENOBLE 1;UNIVERSITETET I OSLO;ORG ENGINEERING AS;UNIVERSITE GRENOBLE ALPES;THE HEBREW UNIVERSITY OF JERUSALEM;WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS";"PL;DK;FR;NO;IL;DE";/LIF;1;0;0;3;0;0 189978;630690;SMART;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-CIG;FP7;Sustainable Mobility and Robust Transportation;2014-05-01;2018-04-30;;"'Traffic Congestion has several effects on travelers, businesses, agencies, and cities. Congestion costs Europe about 1% of Gross Domestic Product (GDP) every year. Transportation networks are complex and large-scale dynamic systems with uncertainties. Efficient traffic control and management of large-scale transportation networks still remain a challenge both for traffic researchers and practitioners. Our main objective in this project is to develop smart transportation systems for large-scale traffic networks that aim at minimizing network delays and increasing sustainable mobility and accessibility, with the help of feeded data from advanced sensor and information technologies. To achieve this goal, we will develop a new interdisciplinary research approach that combines and fuses research areas developed in different fields in traffic theory, control theory, optimal control, optimization, big data mining and fusing, and estimation theory. The SMART project is unique in several aspects, as it is an interdisciplinary research and it is expected to make advances in the state of the art in different directions: (i) Developing a hierarchical scheme of integrated modeling and control for the intersection and network levels. (ii) Developing efficient control strategies that are robust under uncertainties. (iii) Developing implementable real time control based on feeded information for both levels including the monitoring and estimation procedures. (iv) A real field study implementation. We believe that the new interdisciplinary approach will result in a better understanding of complex and congested cities, and will allow integrating traffic control and management approaches to generate smart cities that are more livable and sustainable. The operational deployment of such smart networks would improve the life quality in Europe by improving traffic conditions in cities, reducing travel times and minimizing delays, and reducing pollution levels.'";100000;100000;FP7-PEOPLE-2013-CIG;/MC-CIG;TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY;IL;;;/LIF;1;0;0;3;0;0 102919;294397;MORPHODYNAMICS;ONG;FP7-IDEAS-ERC;ERC-AG-LS3;FP7;Morphodynamics in Plants: from gene to shape;2012-05-01;2018-04-30;;"Morphodynamics is aimed at understanding how shape in plants is controlled during development, a major issue in developmental biology.. So far, research in the field has been mainly based on qualitative observations of mutants, with little considerations for the physics of the cells and tissues leaving many questions unanswered or unexplored. Here, using recent technological advances, to which the applicant has largely contributed, we propose an interdisciplinary and quantitative analysis of molecular and biophysical growth parameters from the cell to the organ level. Because the mechanical properties of the cell wall are generally accepted to control local growth rates and directions, their contribution to morphogenesis will be the central focus. How the molecular regulatory networks, including cell identity genes, influence cell wall synthesis and structure to induce local growth rates and directions is largely unknown at present, mainly because our knowledge lacks integration at different levels of complexity. In addition to the quantitative and interdisciplinary character of this proposal, an original aspect of the project will address the multi-scale nature of a growing tissue, establishing a causality link between local wall properties and multi-cellular outputs. To address this issue, we will combine cutting edge live imaging tools and micromechanical approaches with modelling frameworks recently developed in our laboratory. This will be performed using the developing flower in Arabidopsis, one of the best studied systems in biology and which has the strong advantage to grow without cell migration or rearrangement, vastly facilitating the dialog between the observations and the predictions from the models. In summary, using different interdisciplinary concepts and methods, developed in our laboratory and coming from biology, physics and computer science, we will produce for the first time a mechanistic and multi-scale view of the growing flower bud.";2368004;2368004;ERC-2011-ADG_20110310;/ERC-AG;INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE;FR;;;"/BIO;/LIF";1;0;0;3;0;0 186941;631914;GeneMechMap;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-CIG;FP7;Mapping genetic information into physical space: shape growth in plants;2014-04-01;2018-03-31;;"This Marie Curie Career Integration Fellowship will enable me to establish my own research group aimed at understanding shape growth through the interdisciplinary combination of biology, genetics, physics, and engineering. This proposal aims to decipher and connect the molecular and mechanical mechanisms underlying a special developmental boundary found at the plant apex - the crease that forms between the meristem (stem cell niche) and the new growing organ; the crease boundary is essential for proper plant form and development of lateral branches. The crease represents a uniquely formed tissue exhibiting negative Gaussian curvature, a saddle shape. The growth of such a shape is of principal interest. This proposal also aims to develop and utilize new methodologies for studying cell mechanics in plants, and to use these tools to link molecular players with mechanical outputs required for the generation of meristem-organ boundaries. The information gathered here will contribute to an understanding of how the mechanics of cell growth, and its molecular regulation, contribute to shape generation in plants. This information will serve as a scientific springboard for my career and my group members. This is a truly interdisciplinary project combining molecular genetics, plant physiology, cell wall biochemistry, materials science, engineering, and bioinformatics. The project will help to cement my career path catapult me to the top of this emergent and exciting field, plant biomechanics. It will also serve to enhance the profile of the UK and the ERA as leaders in interdisciplinary and innovative science. This project will benefit the ERA by: the ERA has an edge in this field which I will help maintain, my current ERA collaborations and those within the host institution will help to amplify the field, and my exposure to world class researchers across the ERA will have immeasurable benefits.";100000;100000;FP7-PEOPLE-2013-CIG;/MC-CIG;THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;UK;;;/LIF;1;0;0;3;0;0 187004;631553;MULTI-ROBOT;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-CIG;FP7;Multi-Robot Systems;2014-03-01;2018-02-28;;"The study of multi-robot systems originated from work on distributed robotics in the 1980s and has since promised powerful applications that still have to come to their full realization. The impact that even current technology applied as a multi-robot system can have is aptly demonstrated by the innovations pushed forward by Kiva Systems. These are revolutionizing the automation of warehouses across the U.S. and were acquired by Amazon.com for $775M. This example merely scratches the surface of what is possible with multi-robot systems whose study greatly benefits from a rigorous interdisciplinary approach at the intersection of robotics, control theory, artificial intelligence, and human-robot interaction. The overarching objective of the proposed work is to provide a scientific and practical foundation for the design of multi-robot systems through an application-centric and interdisciplinary approach. The chosen application domains are search and logistics and contributions include the design of models, formal analysis, design and implementation of algorithms, as well as building, testing, and evaluating real systems with human operators. Innovations include multi-objective optimization for adaptive multi-robot coordination in complex environments and the application of crowd-sourcing in combination with cognitive modeling to multi-robot systems. The purpose of this grant application is to enable the realization of the applicant's overall research agenda and support the foundation of a new interdisciplinary research laboratory concerned with the design of multi-robot systems. This laboratory will enable the successful long-term integration of the applicant into the European research community and solidify his international network. The laboratory is anticipated to lead to practical systems but also to have profound impact on the study of cognition in complex systems consisting of the most powerful cognitive agents, robots and humans.";100000;100000;FP7-PEOPLE-2013-CIG;/MC-CIG;THE UNIVERSITY OF SHEFFIELD;UK;;;/LIF;1;0;0;3;0;0 99669;275103;SQuDET;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-IEF;FP7;Advanced Quantum Measurement and Detection for Superconducting Quantum Circuits;2011-08-01;2013-08-14;;"Over the last decade, astonishing progress in superconducting technology has lead to unprecedented control of macroscopic quantum effects in electronic circuits and a feasible route towards fully engineerable “on-chip” quantum systems. Recently, one specific area receiving great international interest and attention is the implementation of quantum optics in the microwave regime, eg, circuit quantum electrodynamics, where optical nonlinearities and light-atom couplings are orders of magnitude stronger than the near-visible equivalents. In this fellowship, we will address the limitations of current quantum detection techniques in this burgeoning, interdisciplinary field of circuit quantum optics. For example, single-photon detectors, which are invaluable off-the-shelf components in standard quantum optics, are not yet available at microwave frequencies, where photon energies are much lower (~200mK). We plan to build a single-photon detector using a novel cross-Kerr coupling, and use this system to develop quantum-nondemolition qubit readout, with a view to implementing quantum feedback and control. We will also explore other forms of nonlinearities accessible using similar devices, augmented by appropriately coupled qubits or SQUIDs. To achieve these goals, this interdisciplinary project will combine the candidate’s expertise in quantum optics & quantum information with the host’s extensive background in superconducting quantum devices. The candidate will be trained to carry out all aspects of superconducting circuit experiments, from design to fabrication & operation. Adding this complementary advanced research competence will provide him with the multidisciplinary expertise perfect for the interdisciplinary field of circuit quantum optics, thereby greatly enhancing his potential to contribute to its development. This fellowship will catalyse a significant development in the candidate’s career and enable him to attain a leading independent position in his new field.";209592,8;209592,8;FP7-PEOPLE-2010-IEF;/MC-IEF;ROYAL HOLLOWAY AND BEDFORD NEW COLLEGE;UK;;;"/EMP;/EDU;/NET";1;0;0;3;0;0 91823;221059;MESOMED;ONG;FP7-PEOPLE;PEOPLE-2007-4-2.IIF;FP7;Marine Environment and Sustainable-fisheries: Observation-Model in the Northern West Mediterranean Sea;2009-01-11;2010-01-10;;"Impacts of climate change and human fisheries on marine environment and resources are focused topics associated with our living environment and sustainability of economy. To protest marine resources, we are seeking to develop 1) quantitative estimates of distributions and production rates of biota, and 2) predictive models for changes by an interdisciplinary approach integrating physical–chemical–biological–socioeconomic processes, and sensor–model development. We are targeting the Gulf of Lions (GoL) in the Mediterranean Sea, and intend to reach the goals: 1) to understand the transport–retention and population dynamics of zooplankton and fish larvae in the GoL, 2) to synthesize our findings with climate change and fisheries, and 3) to apply our results to marine resource management and policy making. These studies will be conducted in both laboratories and field in the GoL by developing sensor packages and models including: 1) A towed physical and biological sensor package, 2) Size (biomass) spectrum mathematical models and theories, and 3) Ecosystem models. Drs. Zhou and Carlotti will form the team consisting of young Ph.D. students and post-doc scientists, and will cooperate with colleagues in LOB to ensure a long term cooperative relationship. The success of this project will significantly improve: 1) The capability to conduct surveys in multiple disciplines at high spatial and temporal scales for addressing interdisciplinary questions, and to model in situ rates and interdisciplinary processes; 2) The capacity to conduct surveys in larger areas, and more frequently, to respond to events, and to produce data products in shorter time because the automatic data acquisition, developed codes for data processing and analysis, and models for process studies; and 3) Integration between in situ observations and models link scientific results from laboratory and field with marine resource management and conservation, and with policy making.";116865,81;116865,81;FP7-PEOPLE-2007-4-2-IIF;/MC-IIF;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FR;;;"/SCI;/COO";1;0;0;3;0;0 89665;215148;IMAGE DDR;ONG;FP7-PEOPLE;PEOPLE-2007-1-1-ITN;FP7;High Resolution Microscopy in the DNA Damage Response;2008-11-01;2012-10-31;;Background: The DNA damage response (DDR) is a specialised stress response fundamental to maintaining genome integrity and suppressing tumour formation. Traditional molecular and cellular biology, combined with genetics and biochemistry, have led to an understanding of the architecture of the DDR in a variety of model organisms and in human cells. These studies have employed populations of cells/molecules and their results are of necessity an average of the response. High sensitivity imaging technologies make it feasible to study events in single cells and to do experiments with small numbers of molecules in vitro. These can now be applied to the DDR. Project Objectives: To provide an interdisciplinary training in single cell and single molecule studies to graduate students in Physics, Chemistry, LS, Maths and Computer sciences. The focus of the research will be the study of the DDR and genome stability. The main technologies to be developed concern high resolution molecular imaging methodologies. Specific aims: To train eight early stage researchers to doctoral level to utilize an interdisciplinary approach to address specific scientific questions and to communicate between disciplines. Study Design: We will achieve our objective by building a network comprising four “local” groups, each a collaboration between an imaging specialist and a cell biologist / molecular geneticists engaged in research on genome stability. The collaborating scientists will serve as co-advisors and will develop a personalised interdisciplinary research training programme for each recruit. Local training will be augmented by specially designed network-wide summer schools, workshops and meetings encompassing all network participants and invited experts. An industrial partner is integral to the network in order to share methods and provide secondments and input into workshops to train researchers in technology exploitation.;2160000;2160000;FP7-PEOPLE-2007-1-1-ITN;/MC-ITN;THE UNIVERSITY OF SUSSEX;UK;"Novartis Forschungsstiftung;GENOMIC VISION SA;BEN-GURION UNIVERSITY OF THE NEGEV;INSTITUT CURIE;UNIVERSITA' DEGLI STUDI DI MILANO-BICOCCA";"CH;FR;IL;IT";"/EMP;/SOC;/EDU";1;0;0;3;0;0 188034;626638;YSCHILLER;CAN;FP7-PEOPLE;FP7-PEOPLE-2013-IEF;FP7;The Philosophy of the Young Schiller (1773-1789). Education, Sources, and Issues;2015-01-01;2016-12-31;;"The proposed project is an interdisciplinary research on the philosophical development of Friedrich Schiller (1759–1805), one of the most prominent European intellectual figures between late Enlightenment and Idealism. The research considers the period from Schiller’s first attendance of philosophy classes in 1773 to his very first adoption of Kantian ideas in 1789, and will provide the first multi-faceted and comprehensive monograph on the young Schiller’s thought, as well as papers and presentations in Europe and the US. The main aim is to demolish the enduring myth of Schiller’s philosophical dilettantism and re-evaluate his philosophical stature independently of Kant. The method will be multi- and interdisciplinary, thus avoiding misinterpretations common to one-sided approaches, connecting the histories of philosophy, literature, ideas and universities. In particular, the research will focus on three aspects of the young Schiller’s commitment to philosophy: a) the curricula, dissertations, theses, speeches and lecture catalogues at the Stuttgart Karlsschule, where Schiller studied from 1773 until 1780; b) the impact of British moral/common sense theory, French Enlightenment and German philosophy on the making of Schiller’s thought; c) key issues in Schiller’s early philosophy such as, for instance, God, knowledge, virtue, beauty, and love. An important shortfall in current scholarship that requires urgent attention and has been repeatedly highlighted in recent times, will thus be addressed. Lastly, the proposal fits closely with the Work Programme and its training objectives in terms of strengthened individual maturity, deepened interdisciplinary consciousness, new (transferable) skill acquisition, and wide dissemination. As a result, the appeal of the European Research Area for scholars in this field will be significantly enhanced.";299558,4;299558,4;FP7-PEOPLE-2013-IEF;/MC-IEF;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;UK;;;;1;0;0;3;0;0 187696;622631;CESINE;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IEF;FP7;Conservation and Ecosystem Services In the New biodiversity Economy;2014-03-15;2016-08-02;;"The overarching project aim is to analyse how biodiversity conservation in the EU is being reconstructed around the measurement of the economic values of nature using the UK as a case study. The project will address three key research gaps: a) the limited amount of interdisciplinary research on recent trends in market environmentalism to recognize and describe the values of ecosystems and biodiversity, (b) the fact that the UK’s global lead in the application of a market-based approach to conservation is under-researched, and (c) the limited amount of critical empirical research in the developed world and especially the EU. The project will describe the regulatory framework and science underpinning the establishment of an ecosystem services framework and biodiversity offsets in the UK and identify their social and conservation outcomes. It will explain how the establishment of these policies is interlinked with governance rescaling processes influencing the distribution of conservation costs and benefits while analyzing how different actors are enrolled into these policy developments. The result will be evidence-based recommendations for the preconditions and sustainability of the biodiversity economy creating insights into the development of social-ecologically resilient policies. The theoretical approach involves biological and social sciences drawing on the interdisciplinary field of political ecology. The methodological approach is based on social science research methods. This project is innovative with potential to transform interdisciplinary scholarship and policy at what may well be a critical point of cultural transformation in conceptions about relationships between humans and the non-human world, their value, management and governance. The variety and quality of the competencies that the Researcher will acquire will have a major impact on reaching a position of professional maturity and research independence inside and outside academia.";299558,4;299558,4;FP7-PEOPLE-2013-IEF;/MC-IEF;THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;UK;;;;1;0;0;3;0;0 100442;286154;SYLICA;ONG;FP7-REGPOT;REGPOT-2011-1;FP7;Synergies of Life and Material Sciences to Create a New Future;2011-10-01;2015-03-31;;"SYLICA – Synergies of Life and Material Sciences to Create a New Future concentrates on unlocking and developing research potential of CEITEC – Central European Institute of Technology located in Brno, Czech Republic. The SYLICA project applicant is Masaryk University, the main beneficiary of CEITEC, and the second largest Czech university. CEITEC concentrates the best teams (51 research groups and 7 scientific programmes) in life sciences and advanced materials research, including interdisciplinary interactions with a promising scientific potential. It is both interdisciplinary and international scope, which create the major added value of SYLICA, and which also need further endeavour based on an international evaluation. SYLICA creates important synergies with the EU Structural Funds; CEITEC expects a large investment worth € 163 mil. from the ERDF into the state-of-the-art infrastructure with national and international significance. By combining ERDF and FP7, the EU added value is created, and a strict complementary approach is followed. SYLICA principally concentrates on the missing expertise for the new core facilities of CEITEC. Through a series of workshops, seminars, postdoctoral and expert inter-ships and visits, and reintegration of experienced nationals, the project will strengthen our research potential on one hand in methodologies and techniques needed for the infrastructure, and on the other hand in the interdisciplinary research fields including studies of novel biomaterials and composites with enhanced biological and mechanical properties. SYLICA will foster strategic partnerships with prestigious EU research institutions and attract external users of the infrastructure and research results including industry. It will contribute to the vision of CEITEC as a flourishing research centre well-networked and integrated in the ERA, training a new generation of researchers, and delivering research results of top level European quality and significance.";4402376;3928918;FP7-REGPOT-2011-1;/CSA-SA;Masarykova univerzita;CZ;;;/REG;1;0;0;3;0;0 111166;329926;STAMUS;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IOF;FP7;Statistical models for musical signal processing;2014-03-15;2017-03-14;;"This project lies in the interdisciplinary field of Music Information Retrieval (MIR). The objective of the project is the development of innovative technologies for enabling access to the immense amount of audio music collections that are available on the Web. Bringing together efforts from speech and signal processing, statistical modeling, musicology and machine learning, we seek to build efficient models that allow the automatic extraction of musical content information from audio signals. We will develop innovative statistical approaches capable of processing information on multiple semantic levels. We will develop a fully-probabilistic model that consists of a single, multi-faceted hierarchical musical structure that is jointly estimated from the music, and that is capable of directly describing the epistemic uncertainty that arises from the effects of the adverse environment in audio music. Concepts from the missing feature theory, which have been applied in robust automatic speech recognition technology, will be integrated to improve the robustness of the MIR algorithms. The objectives and methodologies match the interdisciplinary research profile of the experienced researcher. The high degree of expertise of the two host organizations, both in MIR and Signal and Speech Processing, makes this ambitious project highly feasible. It will also ensure that the experienced researcher will acquire high-level complementary skills that will be fruitful for her research career development in Europe. This interdisciplinary project is a very exciting challenge, and, as the work is disseminated, we expect that it will place European MIR research in a leading position for years to come.";187034,55;187034,55;FP7-PEOPLE-2012-IOF;/MC-IOF;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FR;;;/LIF;1;0;0;3;0;0 105339;316427;ACCLIPHOT;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-ITN;FP7;Environmental Acclimation of Photosynthesis;2012-10-01;2016-09-30;;"AccliPhot is an interdisciplinary, intersectorial research and training network devoted to study photosynthetic acclimation processes in plants and algae. We will train 13 early-stage researchers (ESRs) and 1 experienced researcher (ER) in cutting-edge experimental technologies, modern modelling approaches, industrial applications and a wide spectrum of complementary and industry-relevant skills. In the frame of our research goal to obtain a systems-wide understanding of photosynthetic acclimation processes and their consequences at the organism and population levels, individual research projects and targeted secondments will expose the ESRs to intense interdisciplinary collaborations wielding complementary experimental and theoretical approaches to study photosynthetic acclimation across various scales of biological organisation. Projects will investigate signalling pathways that respond to environmental changes, electron transport chain activity, photosynthetic metabolism and growth of plants and algal populations using four organisms. Fundamental research uncovering novel mechanisms will be performed in Arabidopsis and Chlamydomonas. New knowledge will be applied to the diatom Phaeodactylum tricornutum, which will be subject to industrial research for the biotechnological production of biofuels. With complementary competences acquired in specialised workshops, the ESRs trained in our network will emerge as highly qualified scientists experienced in interdisciplinary collaborations. Exposure to research in the private sector and training in an industrial environment will stimulate their creativity and enhance their entrepreneurial spirit, thus optimising their perspectives on the European job market in academia, industry and beyond. Our research activities will have a long-term impact supporting the optimisation of crop productivity and the development of cost-effective strategies for algal biofuel production.";4028607,56;4028607,56;FP7-PEOPLE-2012-ITN;/MC-ITN;HEINRICH-HEINE-UNIVERSITAET DUESSELDORF;DE;"THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN;UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6;UNIVERSITA DEGLI STUDI DI VERONA;MARTIN-LUTHER-UNIVERSITAET HALLE-WITTENBERG;UNIVERSITE DE GENEVE;CELLECTIS SA;FERMENTALG SA;EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH;OXFORD BROOKES UNIVERSITY;UNIVERSITE DE NANTES;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;DAITHI O'MURCHU MARINE RESEARCH STATION LTD";"UK;FR;IT;DE;CH;IE";/LIF;1;0;0;3;0;0 109140;605162;BERTI;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-ITN;FP7;Biomedical Imaging & Informatics – European Research and Training Initiative;2013-10-01;2017-09-30;;"'Current research in Biomedical Imaging & Informatics (BI&I) is driven by the interaction of the natural sciences, informatics & engineering, and medicine. Education and training of early stage researchers (ESR) is, however, often still centred within only one of these domains, resulting in researchers often neither acquiring necessary knowledge of clinical needs, nor sufficient understanding of disciplines beyond BI&I. Furthermore, ESR working in BI&I still face a ‘cultural gap’ between natural sciences and informatics & engineering with the natural sciences achieving innovation by basic research and informatics & engineering approaching this through technological applications. However, the traditional separation into disciplines and cultures breaks up once the researcher is faced with biomedical questions. An interdisciplinary education, solid knowledge of areas adjacent to the core research field, as well as business competences are therefore the keys to successful, innovative research and excellent science. The proposed IDP BERTI aims to meet all these new requirements. BERTI will establish an interdisciplinary and intersectoral European network of computer scientists, natural scientists, engineers, clinicians, and partners from industry, hence meeting the objectives of the EU Innovation Union “to attract and train young people to become researchers and offer internationally competitive research careers to keep them in Europe and attract the best from abroad.” Each ESR will be assigned one academic, one medical supervisor, as well as a mentor from our industry partner GE Global Research, ensuring perfect training for both an academic and industry career. Due to the truly interdisciplinary nature of BERTI, we feel that an evaluation on a solely natural science/engineering basis will not suffice to grasp the full extent of BERTI. Therefore, we kindly ask that the life science and medical aspects of our proposal be given due attention during the evaluation process.'";3094708,1;3094708,1;FP7-PEOPLE-2013-ITN;/MC-ITN;TECHNISCHE UNIVERSITAET MUENCHEN;DE;;;/LIF;1;0;0;3;0;0 104697;316422;eLiQuiD;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-ITN;FP7;Best Engineering Training in Electric, Lightweight and Quiet Driving;2012-10-01;2016-09-30;;"Engineering for future mobility must be inspired by ecology and economy to enable green and silent vehicles. Current university based education is focusing on classical fields like mechanical engineering on one side with some aspects of Noise, Vibration & Harshness (NVH) and LightWeight Design (LWD) or like electrical engineering covering aspects of “Electrification” & “Hybridisation” on the other side. The proposed eLiQuiD project (Best Engineering Training in Electric, Lightweight and Quiet Driving) aims to bring together early stage researchers and experienced specialists from key players in academia and industry across Europe covering NVH, LWD and H/E disciplines to form a broad range of backgrounds. Recent research underlines the strong interaction and shows the often conflicting demands of these 3 topics. Consequently, an optimum for future vehicle development requires an interdisciplinary education in this triangle of topics. eLiQuiD’s focus is to motivate and encourage early stage researchers for scientific work in the new interdisciplinary research fields NVH\LWD, LDW\H/E and H/E\NVH. The fellows will be trained and supported in their phase of doctoral thesis to find innovative PhD topics as well as to receive specific education in theoretical and practical trainings. The education will comprise existing lectures in the partner network as well as training specifically developed for the interdisciplinary needs. eLiQuiD is formed by two participating hosts, combining leading education and research institutions as well as an associated partner, well established in European automotive R&D, to assist in the dissemination and outreach or eLiQuiD results. Thus the engineers will participate in both the scientific research work and the practical application of new methods of testing and simulation. They will profit from extended international knowledge after their academic education when starting to work in the industry.";950610,82;950610,82;FP7-PEOPLE-2012-ITN;/MC-ITN;KATHOLIEKE UNIVERSITEIT LEUVEN;BE;Kompetenzzentrum - Das Virtuelle Fahrzeug, Forschungsgesellschaft mbH;AT;/LIF;1;0;0;3;0;0 100426;290050;GRESIMO;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-ITN;FP7;Best Training for Green and Silent Mobility (GRESIMO);2011-10-01;2015-09-30;;"Engineering for future mobility must be inspired by ecology and economy to enable green and silent vehicles. Current university based education is focusing on classical fields like mechanical engineering on one side with some aspects of Noise, Vibration & Harshness (NVH) and Light Weight Design (LWD) or like electrical engineering covering aspects of “Electrification” & “Hybridisation” on the other side. The proposed GRESIMO project (Best Training for Green and Silent Mobility) aims to bring together early stage researchers and experienced specialists from across industry and academia in Europe covering NVH, LWD and H/E disciplines to form a broad range of professional background. Recent research underlines the strong interaction and shows the often conflicting demands of these 3 topics. Consequently, an optimum for future vehicle development requires an interdisciplinary education in this triangle of topics. GRESIMO focus is to motivate and encourage early stage researchers for scientific work in the new interdisciplinary research fields NVH\LWD, LDW\H/E and H/E\NVH. The fellows will be trained and supported in their phase of doctoral thesis to find innovative PhD topics as well as to receive specific education in theoretical and practical trainings. The education will comprise existing lectures in the partner network as well as training specifically developed for the interdisciplinary needs. GRESIMO is formed by a group of participating hosts, combining leading education and research institutions as well as industrial enterprises in 6 countries of the EC. Thus the engineers will participate in both the scientific research work and the practical application of new methods of testing and simulation. They will profit from extended international knowledge after their academic education when starting to work in the industry. Furthermore, the industry will gain from the specific training of the young researchers for the requirements to develop green and silent vehicle.";3418118;3418118;FP7-PEOPLE-2011-ITN;/MC-ITN;Kompetenzzentrum - Das Virtuelle Fahrzeug, Forschungsgesellschaft mbH;AT;"FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.;UNIVERSITA DEGLI STUDI DI FIRENZE;DAIMLER AG;SIEMENS INDUSTRY SOFTWARE NV;PSA AUTOMOBILES SA;AVL LIST GMBH;KATHOLIEKE UNIVERSITEIT LEUVEN;UNIVERZA V LJUBLJANI";"DE;IT;BE;FR;AT;SI";"/LIF;/SCI";1;0;0;3;0;0 95023;253756;EIW3R;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IEF;FP7;The Ethics of Information Warfare: Risks, Rights and Responsibilities;2010-06-01;2012-05-31;;This is a two-year research project on the ethical implications of information warfare. Information warfare is a new form of conflict characterised by strategies designed to strike at communication nodes and infrastructures, and by the deployment of artificial agents as tools of offence (robotic weapons). It has its roots in the military use of intelligence as a strategic means, but has developed thanks to the revolutionary transformations caused by the pervasive use of Information and Communication Technologies (ICT) and Artificial Intelligence (AI) artefacts on the battlefield. The overall research objective is to provide an ethical analysis of information warfare, which will seek to solve three ethical problems: 1. How can the risks of increasing the number of ICT-based conflicts in the world and hence of civilian casualties be avoided? 2. How can the erosion of individual rights of privacy, anonymity and personal liberty be balanced against the right of a community to be safe from cyber-attacks? 3. How can the levels of responsibilities for the actions performed by robotic weapons be fairly evaluated? The objective will be achieved by developing an interdisciplinary ethical study, combining research in Information and Computer Ethics (ICE) with the acquisition of relevant expertise in ICT and AI. The project will be developed in collaboration with leading European experts, and fully supported by the UNESCO Chair of Information and Computer Ethics, held by Prof. Floridi at the University of Hertfordshire, UK. The novelty and importance of the problems tackled by the project and its interdisciplinarity will enable the researcher to acquire new skills and advanced expertise and to stand as an independent and mature scholar. The project will benefit the Work Programme by enhancing long lasting interdisciplinary cooperation among leading European experts in ICE, ICT, and AI and by promoting a European approach to the ethics of information warfare.;166040,8;166040,8;FP7-PEOPLE-2009-IEF;/MC-IEF;THE UNIVERSITY OF HERTFORDSHIRE HIGHER EDUCATION CORPORATION;UK;;;"/SCI;/EDU;/ITT";1;0;0;3;0;0 98630;267184;MULTIMOD;ONG;FP7-IDEAS-ERC;ERC-AG-PE1;FP7;Multi-Mathematics for Imaging and Optimal Design Under Uncertainty;2011-04-01;2016-03-31;;"The aim of this interdisciplinary project is to develop new mathematical and statistical tools, probabilistic approaches, and inversion and optimal design methods to address emerging modalities in medical imaging, nondestructive testing, and environmental inverse problems. It merges the complementary expertise of the investigators in order to make a breakthrough in the field of mathematical imaging and optimal design by solving the most challenging problems posed by new imaging modalities. The PI and Co-PI are leading experts in their respective fields (applied analysis and probability) and their researches have very strong interdisciplinary nature. The goal of this project is to synergize asymptotic imaging, stochastic modelling, and analysis of both deterministic and stochastic wave propagation phenomena. We want to throw a bridge across the deterministic and stochastic aspects and tools of mathematical imaging. This requires a deep understanding of the different scales in the physical problem, an accurate modelling of the noise sources, and fine mathematical analysis of complex phenomena. The emphasis of this project will be put on deriving for each of the challenging imaging problems that we will consider, the best possible imaging functionals in the sense of stability and resolution. For optimal design problems, we will evaluate the effect of uncertainties on the geometrical or physical parameters and design accurate optimal design methodologies. In this project, we will build an exceptional interdisciplinary research and an innovative approach to training in applied mathematics. We will train a new generation of applied mathematicians who will master both the probabilistic and analytical tools to best meet the challenges of emerging technologies.";1920000;1920000;ERC-2010-AdG_20100224;/ERC-AG;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FR;;;"/PSE;/MST";1;0;0;3;0;0 101167;290308;SHEMAT;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-ITN;FP7;Training Network for Self-Healing Materials: from Concepts to Market;2012-01-01;2015-12-31;;"The aim of the present Marie Curie project proposal is the development of self-healing materials, the market implementation for the most promising material concepts and developments as well as the training of young scientists and their knowledge transfer in mutual interaction programs due to the distinct interdisciplinary shape of the project. The partners intend to address both actual fundamental research in material development as well as the complementary aspects of conceptual process chain analysis from a more industrial perspective. We have chosen to restrict our research to self healing material concepts with an existing sizeable academic development base and a sufficient number of positive findings to ensure a significant possibility of successful conversion to industrial application. If we succeed in bridging the gaps in knowledge and understanding for these promising materials, industrial development of these concepts and technologies is to be expected. This can only be achieved if specific interdisciplinary training is provided to young researchers, to master the concepts, know how to quantify healing, and how to position these materials in the application fields. Finally, it should be made clear that, notwithstanding the industrial oriented approach in this proposal, the work to be undertaken will always be of the highest scientific/academic character and aims to set a new standard in the development of novel material concepts. The objects of the proposal are -training and education for junior researchers and a strong support for the interdisciplinarity of the project to ensure technology transfer from laboratory research to industrial application -promote actual self-healing strategies an concepts that address current materials or engineering limitations to application -exploit the existing scientific and technological leadership of the partners to deliver viable and advanced solutions for the commercial exploitation of self-healing materials.";3891406,66;3891406,66;FP7-PEOPLE-2011-ITN;/MC-ITN;FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.;DE;"AVECOM;ECOLE SUPERIEURE DE PHYSIQUE ET DECHIMIE INDUSTRIELLES DE LA VILLE DEPARIS;UNIVERSITEIT GENT;ALBERT-LUDWIGS-UNIVERSITAET FREIBURG;ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE;GKT GUMMI - UND KUNSTSTOFFTECHNIK FURSTENWALDE GMBH;UNIVERSITY OF BRISTOL;TECHNISCHE UNIVERSITEIT DELFT";"BE;FR;DE;CH;UK;NL";"/LIF;/SCI";1;0;0;3;0;0 108595;328010;ELTA;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IEF;FP7;ELTA Everyday Lives: (Re)Conceptualising Transitions to Adulthood for Young People in Care;2013-09-01;2014-08-31;;"'Across Europe, young people in public care are known to be at risk of poor outcomes in adult life, in relation to indicators including education, health, homelessness and crime. To address such disadvantage and support transitions from care to adulthood, research must attend to the complexity of young people’s everyday lives, located in social and cultural contexts and entwined with family and community. The IEF will address these critical concerns in a training-through-research project, focused on theoretical and methodological development. It aims to inform cross-national understandings of outcomes through a biographical (re)conceptualisation of ‘transitions’ that draws on cutting edge theory and methodology in youth and family studies. The project will make a substantive contribution to a critical knowledge gap, by: (a) developing a new theoretical and methodological framework for the study of everyday family lives and transitions to adulthood in research with young people in care; and (b) testing this framework in an exploratory cross-national comparative study that combines analysis of new data collected with young people in public care in France and England and archived general population data from young people who participated in the landmark UK Inventing Adulthoods study. This work will develop the fellow’s career in three core areas: (i) establishing new interdisciplinary and cross-national understandings; (ii) developing cutting edge methodological skills; and (iii) gaining a broad interdisciplinary and international social scientific experience and transferable skills, including experience of cross-national project leadership and the creation of future collaborative opportunities within and beyond the host research team. The fellow, scientist in charge and collaborator each bring distinctive disciplinary knowledge and cross-national experience, together building new interdisciplinary understandings across country contexts.'";115641,6;115641,6;FP7-PEOPLE-2012-IEF;/MC-IEF;THE UNIVERSITY OF SUSSEX;UK;;;/SCI;1;0;0;3;0;0 100674;290201;MEDGATE;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-ITN;FP7;Reconstructing Mediterranean-Atlantic exchange during the Miocene;2012-02-01;2016-01-31;;MEDGATE combines the expertise of 29 geoscientists from both the oil industry and academia in the training of 10 researchers. It aims to equip these researchers for successful careers in either sector through interdisciplinary projects focussing on an intriguing problem which has implications for both environmental change and hydrocarbon exploration. The research aim of MEDGATE is to reconstruct the evolution of the marine corridors that linked the Atlantic and Mediterranean prior to the formation of the Gibraltar Straits about five million years ago. Closure of these gateways led to catastrophic changes in Mediterranean sea-level and salinity and to the formation of hydrocarbon accummulations. Despite decades of research, the exact timing of closure, the geometry of the corridors and the pattern of exchange through them, remains uncertain. Previous work has been conducted mainly using single research methodologies. The MEDGATE project provides a unique opportunity to undertake a suite of ten interdisciplinary projects that integrate state-of-the-art technologies, surface and subsurface datasets and expertise supplied by both academic and industrial partners. These new data will clarify the environmental impact of gateway exchange and help assess the petroleum potential of the region. MEDGATE network-training programme will support the skill requirements of each project and foster interdisciplinary collaboration. It also emphasises training in advanced field geology and biostratigraphy, to address the declining skill levels in geoscience graduates reported by MEDGATE’s industrial partners. All eleven participating institutions will contribute substantially to network-wide technical and complementary skills training and each institution has committed to seconding one or more researchers. This will provide them with access to the expertise, facilities and experience they require to carryout their project and launch them on a successful geoscience career.;2692902;2692902;FP7-PEOPLE-2011-ITN;/MC-ITN;UNIVERSITY OF BRISTOL;UK;"REPSOL;UNIVERSITEIT UTRECHT;UNIVERSITY OF GLASGOW;UNIVERSIDAD DE SALAMANCA";"ES;NL;UK";"/LIF;/SCI";1;0;0;3;0;0 109601;612620;ILSES;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IRSES;FP7;Metal nanoparticle interactions with bioorganic molecules and their applications in biosensing;2013-08-01;2017-12-31;;"This project aims strengthening interdisciplinary and technological collaboration between the scientists working in the topical areas of nanooptics and nanoplasmonics. These subjects investigate unique optical properties of nanoparticles and nanostructured surfaces, which are amazingly useful for improving optical materials, sensing bioorganic molecules, progress in solving of biophysical and biochemical tasks. Exchange by knowledge in such subject matter as giant Raman scattering (SERS), Surface Enhanced Infrared Absorption (SEIRA), metal enhanced fluorescence et al. is planned to organize in form of International Laboratory of Surface Enhanced Spectroscopy(ILSES). It is proposed to organize such laboratory by means of collective access to existing scientific equipment and technological achievements of partners using a system of mutual scientific journeys, meetings and workshops. From the viewpoint of applied science, the proposed partnership contributes to the extremely important and innovatively attractive field: the development of the new complex nanoparticle/bioorganical molecules and development of cheap and effective SEIRA and SERS nanostructured substrates. Since each partner brings its unique and specific expertise to reach the project objectives, the proposed partnership is very important, both for the area of collaboration and for the ERA as a whole. The main expertise of the participating teams cover different areas of present-day physics, biology and chemistry. Thus, the consortium joins scientists from several scientific communities under the common roof of the interdisciplinary research on metal nanoparticle interactions with bioorganic molecules. In addition to the interdisciplinarity of the teams, young scientists are to be widely involved which will allow a sustainable dissemination of knowledge. Thus, besides the scientific results, the project is expected to bring new research experience for young participants unavailable at home institutions.";196100;196100;FP7-PEOPLE-2013-IRSES;/MC-IRSES;TARTU ULIKOOL;EE;"UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6;UNIVERSITAT LINZ;UNIVERSITA DEGLI STUDI DI TORINO;FREIE UNIVERSITAET BERLIN";"FR;AT;IT;DE";/LIF;1;0;0;3;0;0 95636;256439;YOGALOKACNTXT;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-RG;FP7;"""The Concept of """"World"""" (Sattva-bhAjana-loka) in Indian Early YogAcAra Buddhism: An Intellectual History""";2011-02-20;2015-11-22;;"Current scholarship on the philosophy of early Indian YogAcAra Buddhism (4th-5th centuries CE) has come under criticism for its de-contextualized understanding of the school's worldview. My research addresses this shortcoming through an intellectual history of the Yogacara's philosophical, cosmological and literary understanding of 'sattva-bhAjana-loka' (the sentient and insentient 'external world'), a fundamental concept that has not received adequate treatment in Scholarship to date. Understanding loka as a unique and pervasive social fact within the Yogacara worldview, this research will: (1). supply a genealogy of the Yogacara's understanding of loka by historically contextualizing it in the school's texts (Sanskrit, Tibetan, and Pali) and in the works of its Indian intellectual milieu. (2) Examine the ways in which the Yogacara's notion of loka - as an intersubjective, illusionary realm - is constructed by the imagery and metaphor of the school's shastric and sutra literature. Contextualizing philosophical analysis with cosmology and imagery, this interdisciplinary research aims to supply a more complete and nuanced picture of the Yogacara's worldview, which will in turn (1) contribute to the clarification of current debates over the schools core doctrines, and (2) contribute to an ongoing and increasingly influential interdisciplinary analysis of intersubjectivity, engaging Buddhist Studies, Philosophy of Mind and Phenomenology. Having recently returned from my doctoral studies at Columbia University in New York to assume a tenure-track position (starting in 2010) in Tel Aviv University’s East and South Asian Department, the IRG would enable me to conduct this research comprehensively (at two leading European research institutes, among other locations), leading to the delivery of a book manuscript and several peer review journal articles, as well as to the organizing of an international interdisciplinary conference";87500;87500;FP7-PEOPLE-2009-RG;/MC-IRG;TEL AVIV UNIVERSITY;IL;;;/SCI;1;0;0;3;0;0 108166;329121;EPICS;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IEF;FP7;"""Epistemology in psychological science, the heritage of Giambattista Vico and the cultural psychology.""";2013-04-01;2015-03-31;;"'The project is aimed at analyzing the basic historical and psychological roots of the EU civil societies over the past centuries. The analysis will shed light on the epistemological status of psychological knowledge, by reconstructing the influence of Giambattista Vico’s ideas (concepts of verum factum, historical situatedness of higher mental processes and sensus communis), using this study to define the epistemological challenges, and to understand how concepts in psychology are theoretically elaborated, empirically constructed and generalized. Candidate’s career objective is to integrate his scientific profile with theoretical and epistemological innovative competences at Aalborg University (Denmark) to successfully compete for a position of associate professor in psychology in Italy, Denmark, or other EU countries, within 3 years. The candidate will improve theoretical and research skills; acquire the linguistic and writing skills to work in Denmark and to achieve the national professorship habilitation in Italy; improve the candidate’s high quality international publication track, making the candidate’s profile competitive also for other ERA countries; strengthening the candidate’s international network and the interdisciplinary skills; improving his autonomy and management skills and preparing new research funding proposals at national and EU level. The research activity will also include teaching epistemology courses at Aalborg University and thesis supervision. Danish psychology has been influenced by Vico’s ideas. This historically documented sensitivity, combined with the specific interdisciplinary research focus on cultural psychology, makes Aalborg University the ideal location for developing the project. Dept. of Communication & Psychology is developing a long-term research, training and economic effort in its interdisciplinary program on cultural psychology that fits the best the candidate’s training and career development objectives'";230809,8;230809,8;FP7-PEOPLE-2012-IEF;/MC-IEF;AALBORG UNIVERSITET;DK;;;/SCI;1;0;0;3;0;0 97793;247551;INECHD;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IRSES;FP7;International Network for Early Childhood Health Development;2011-03-01;2015-02-28;;The general aim of the INECHD is to strengthen collaborative interdisciplinary research and knowledge transfer on early childhood health development and well-being. Recent research from numerous disciplines clearly highlights the importance of early childhood development (pregnancy to school entry) for the prevention of long term health and social adjustment problems. Large interdisciplinary-international research projects are needed to understand the interplay between bio-psycho-social mechanisms and to find effective preventive interventions. The network brings together partners from three continents: Europe (University College Dublin-Ireland and Inserm, France), North America (Laval and Montreal universities in Canada) and South America (Pontificia Universidade Catolica do Rio Grande do Sul in Brazil and Universidad Alberto Hurtado in Chile) to initiate, reinforce and extend research and knowledge transfer collaborations. Leaders of the program have extensive experience of longitudinal-experimental studies and international collaborations. Staff exchange will enable partners to share data banks from large population-based longitudinal studies and experimental interventions, plan new studies and develop a web-based tool to transfer best practice knowledge to service providers and policy makers in four of the European Community languages: English, French, Portuguese and Spanish. Over a four year period a total of 48 researchers will benefit from secondments. European researchers will spend a total of 200 months in North and South America, while South and North Americans will also spend a total of 200 months in Europe. An emphasis will be placed on training early career researchers for international and interdisciplinary longitudinal-experimental studies on early childhood development.;720000;619200;FP7-PEOPLE-2009-IRSES;/MC-IRSES;UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN;IE;INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE;FR;"/SCI;/EDU;/ITT";1;0;0;3;0;0 191261;628179;HIATUS LPLEIS IBERIA;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IEF;FP7;Testing population hiatuses in the Late Pleistocene of Central Iberia: a geoarchaeological approach;2015-01-01;2016-12-31;;"Our project focuses on the Late Pleistocene human settlement of the central area of the Iberian Peninsula. Namely, it deals with the time span between the Late Middle Palaeolithic and the Solutrean (around 60,000 – 20,000 years before present). For years, it has been assumed that a population hiatus existed in Central Iberia from the Late Middle Palaeolithic to the final stages of the Solutrean. This has been traditionally explained as a consequence of the harsh ecological conditions of the area during the Last Glaciation. However, recent data coming from the South-East foothills of the Iberian Central Range (Northwest of Guadalajara province) have questioned this model. According to these new data, still scarce and preliminary, we have devised a project aimed to investigate the temporal and geographic extent of the purported Late Pleistocene human hiatus in Central Iberia. We intend to know the nature of this hiatus in terms of human-environment interaction. In order to do that, we propose to conduct new field and laboratory works on three palaeolithic sites located in Northwest Guadalajara. Our methodology will be interdisciplinary, including high-resolution geoarchaeology, lithic technology, and chronometric dating. Results will be discussed both at the Iberian and European levels. We will investigate if population dynamics in Iberia can be explained in terms of European human mobility in the context of global Late Pleistocene climate change. The host institution will be the Neanderthal Museum (Germany). Researchers from this institution are currently involved in an interdisciplinary collaborative research project aimed to study human-environment interaction at the European level. Thus, integration of the proposed project within this wider research framework will provide the applicant with an outstanding context for discussing data and proposing new models at a European scale. It will also provide him with an excellent interdisciplinary training.";161968,8;161968,8;FP7-PEOPLE-2013-IEF;/MC-IEF;STIFTUNG NEANDERTHAL MUSEUM;DE;;;;1;0;0;3;0;0 94776;251950;SEMIP 2;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IEF;FP7;Subjectivity and Self-Effectivity. Investigating Self-Determination in Mentally Ill People from the First-Person-Perspective;2010-05-01;2012-02-29;;The fellowship improves Jann E. Schlimme’s scientific and complementary skills in the interdisciplinary field of philosophy and psychiatry. In this research project self-determination in mentally ill people will be investigated in terms of self-effectivity (SE) from the First-Person-Perspective. At first a detailed description of the experiential structure of the process of SE will be achieved by applying a phenomenological method. Then this structure of SE will be investigated more thoroughly in constant comparison with understandings of mental disorders (e.g. addiction, suicidality). It is expected that SE is a crucial process for self-determination and that therefore characteristics of self-determination and of its special impairments in mental disorders can be spelled out in terms of SE. The results will be published. Schlimme is a clinically excellently trained senior registrar and senior lecturer for psychiatry at Hannover Medical School with an interdisciplinary academic education. Though he is an experienced researcher in psychiatry applying methods rooted in humanities, he needs a profound (philosophical) training for reaching professional maturity in this interdisciplinary field. In this fellowship he will be trained under the supervision of Sonja Rinofner-Kreidl at the department of Philosophy (University of Graz) and integrated in her working group. The fellowship enables him to achieve the necessary skills for a professorship. The project’s topic is of principal importance for psychiatry, since regaining, stabilizing and improving the patient’s self-determination is the major goal of psychiatry and needs new attention due to radical changes in our understanding of subjectivity. The detailed description of the experiential structure of the process of SE opens the field of self-determination for further research and helps to improve psychiatric treatment in the EU via describing guidelines regarding the empowerment of mentally ill people.;218173,6;218173,6;FP7-PEOPLE-2009-IEF;/MC-IEF;UNIVERSITAET GRAZ;AT;;;"/SCI;/EDU;/ITT";1;0;0;3;0;0 89670;217453;ECOINNO2SME;ONG;FP7-SME;SME-3;FP7;Support SMEs in Disseminating and Exploiting Research Results of ECO-Innovation;2008-02-01;2010-03-31;;"ECOINNO2SME comprises 7 partners from 7 European countries (DE, EE; ES; HU, IT, SE, UK) all with long experiences in supporting SMEs in dissemination and exploitation of research results. The overall aim of the project is to reinforce the dissemination and explotation of project results of SMEs in the areas Eco-Innovation in such a way that they are supported to bridge the gap between research and exploitation, hence expand their businesses and, accordingly, raise their competitiveness in the world markets. As ECO-Innovation is of crucial importance for the economic development and of high actual public interest in Europe, ECOINNO2SME will concentrate on this cluster. The project will evaluate completed FP5/6-projects with the involvement of SMEs in view of identifying key success factors and good practices for dissemination and exploitation of results. By defining sub-clusters of ECO-Innovation (e.g. energy, waste, eco-products) the project will follow an interdisciplinary approach in order to support exploitation and dissemination of results in these clusters. Through different kinds of activities like interdisciplinary platform meetings (regional ,EU-level) as well as through specific road shows in partner countries, SMEs will be able to exchange good practices and to meet strategic exploitation partners. Project results will be constantly assessed and disseminated via the project’s website. A final assessment of the interdisciplinary approaches will be made and disseminated to other multipliers as well as to the EC in order to reach the outmost impact on reinforcing the exploitation activities of SMEs in Europe and to contribute positively to the creation of a lead market for ECO-Innovation in Europe, too.";741303,75;728742,5;FP7-SME-2007-3;/CSA-SA;STEINBEIS INNOVATION GGMBH;DE;"TUDOMANYOS ES TECHNOLOGIAI ALAPITVANY;INNOVA SRL;INSTITUTO TECNOLOGICO DE ARAGON;LANSTEKNIKCENTRUM I JONKOPINGS LAN AB;TARTU BIOTEHNOLOOGIA PARK AS;BETA TECHNOLOGY LTD";"HU;IT;ES;SE;EE;UK";"/ECO;/SCI;/COO";1;0;0;3;0;0 92332;235863;PROFOLANT;ONG;FP7-PEOPLE;FP7-PEOPLE-IEF-2008;FP7;PRODUCTION, TRADE AND CONSUMPTION OF FOOD IN LATE ANTIQUITY AND EARLY MIDDLE AGES;2009-11-01;2011-10-31;;"FOOD IS RELATED TO THE ENVIRONMENT, CULTURE AND HISTORY OF SOCIETIES AND IT IS AN IMPORTANT ASPECT OF CULTURAL IDENTITY. KNOWING THE HISTORY OF FOOD CAN HELP TO UNDERSTAND THE CONTEMPORARY FOOD PRACTICES AND PRESERVE THEM. THE PROJECT IS AIMED AT FILLING THE GAP OF KNOWLEDGE ON THE FOOD PRODUCED, TRADED AND CONSUMED IN LATE ANTIQUITY AND EARLY MIDDLE AGES. AN INTERDISCIPLINARY APPROACH IS PROPOSED TO STUDY THE ARCHAEOLOGICAL RECORD TO UNDERSTAND THE DIFFERENT TRACES OF FOOD, SUCH AS ANIMAL BONES, BOTANIC REMAINS, AND CERAMIC VESSELS USED IN THE DIFFERENT PHASES OF THE FOOD LIFE CYCLE (PRODUCTION, PREPARATION, STORAGE, TRANSPORT, CONSUMPTION AND DISCARD). IN PARTICULAR, DIFFERENT ARCHAEOMETRIC TECHNIQUES WILL BE USED TO STUDY CERAMICS, THAT ARE CONSIDERED GOOD MARKERS OF SOCIAL ORGANIZATION AND TRADE. ANALYSES WILL BE APPLIED TO UNDERSTAND THE FOOD STORED, PREPARED AND CONSUMED, AND THE WAY OF PREPARING IT. THIS WILL BE COMPLEMENTED WITH THE STUDY OF CERAMIC PROVENANCE, TO UNDERSTAND THE TRADE OF FOOD BETWEEN DIFFERENT SITES AND GROUPS OF PEOPLE. AMPHORAE AND COMMON CERAMICS (I.E. COOKING VESSELS) WILL BE ANALYSED. ALSO THE STRUCTURES WHERE FOOD WAS PRODUCED, PREPARED AND CONSUMED WILL BE STUDIED. THE SITES CHOSEN FOR THIS STUDY ARE SITUATED IN THE BALEARIC ISLANDS, THAT HAD A CENTRAL POSITION IN THE LATE ANTIQUE MEDITERRANEAN TRADE NETWORK AND SHARED A COMMON HISTORY IN THE PERIOD. EXPERIMENTS AND ETHNOARCHAEOLOGICAL INVESTIGATIONS OF FOOD PRODUCTION STRUCTURES (I.E. FOR THE TRADITIONAL PRODUCTION OF OILS) WILL BE DONE. THIS WILL GIVE DATA TO BE USED FOR THE INTERPRETATION OF THE ARCHAEOLOGICAL CONTEXTS. THE PROJECT WILL GIVE THE FELLOW THE POSSIBILITY OF GOING DEEP IN ALL THE ASPECTS OF THE INTERDISCIPLINARY RESEARCH, AND LEARNING NEW TECHNIQUES. IT WILL PROVIDE HER WITH THE POSSIBILITY TO BE FORMED IN COMMUNICATION SKILLS, MANAGEMENT OF PROJECTS; AND ALL WILL REINFORCE HER LEADERSHIP IN THE FIELD, LETTING HER GROWING IN HER CAREER.";;152968,04;FP7-PEOPLE-IEF-2008;/MC-IEF;UNIVERSITAT DE BARCELONA;ES;;;"/SCI;/EMP";1;0;0;2;0;0 99064;274032;hqsmcf;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-IOF;FP7;Homotopy quantum symmetries, monoidal categories and formality;2012-01-01;2014-12-31;;"This project will be hosted at the MIT (outgoing host) and at the University of Zurich (return host). Its main objectives are : (I) to develop a theory of homotopy quantum groups. This can be understood as the natural the- ory that should sit at the intersection of four important disciplines of mathematics and physics : monoidal categories, homotopy theory, quantum groups and higher categories. This fact gives a clear multidisciplinary aspect to the proposal. (II) to prove the formality of the homotopy Lie algebra governing simultaneous deformations of a Poisson manifold and its coisotropic submanifolds. This is the key step in solving the problem of quantization of symmetries from the point of view of deformation quantization, giving interdisciplinary applications. These two objectives organize themselves into subobjectives : I1 ) define homotopy braided monoidal categories (?-braided ?-monoidal category) I2 ) define homotopy quasi-triangular quasi-Hopf algebras (?-triangular ?-Hopf algebras) I3 ) define monodromy for higher connections I4 ) give examples of higher Drinfeld associators I5 ) define and give examples of homotopy quantum groups II1 ) construct the homotopy Lie algebra governing simultaneous deformations of a Poisson manifold and its coisotropic submanifolds II2 ) prove the formality of this homotopy Lie algebra. Interdisciplinary aspects come also from tools used which are borrowed from physics (higher holonomies, branes, quantization) or from new rewriting techniques in computer science and operads (Gröbner basis).";225233,6;225233,6;FP7-PEOPLE-2010-IOF;/MC-IOF;UNIVERSITAT ZURICH;CH;;;"/EMP;/SOC;/COO";1;0;0;2;0;0 97176;264772;CHEBANA;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-ITN;FP7;Chemical Bioanalysis;2010-12-01;2014-11-30;;"Chemical Bioanalysis aims for retrieving selective information out of complex biological systems. Sensors, probes and devices are the future tools of medicinal diagnostics, environmental monitoring, food analysis and molecular biology. The ITN CHEBANA provides interdisciplinary research training for early stage and experienced researchers and focuses on the most important techniques in the field. These are based on fluorescence, electrochemistry and mass spectrometry. Eleven excellently qualified academic partners (with well documented expertise) along with one of Europe’s leading industrial companies in the diagnostic area will provide a network of research activities, short courses and classes that are complemented by skill training and career development events. In fact, we believe that we have unified Europe's leading experts in these fields, many of which outperform their American and other colleagues. Moreover, joint research projects between the partners build the foundation of the training network. The research activities are divided into four overlapping areas: * sensor development for the detection of small analytes, * monitoring of biomolecular interactions, * analysis of cellular function, and * development of diagnostic tools. Interdisciplinary expertise and specialized techniques are mandatory in order to accomplish these challenges, and this cannot be provided at a single institution at the required level. Therefore, a European hub for research and training in the fast developing field of Chemical Bioanalysis is assembled by co-supervised PhD theses, postdoctoral training, workshops and summer schools bringing together the individual expertise of the partners from academia and industry. Eventually, this ITN will provide highly specialized experts that are urgently looked for by the respective European industry.";5757837;5757837;FP7-PEOPLE-2010-ITN;/MC-ITN;UNIVERSITAET REGENSBURG;DE;"TECHNISCHE UNIVERSITAET GRAZ;ROCHE DIAGNOSTICS GMBH;VILNIAUS UNIVERSITETAS;EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH;UNIVERSITA DELLA CALABRIA;UNIVERSITAT AUTONOMA DE BARCELONA;LUNDS UNIVERSITET;UNIVERSITY OF LEICESTER;CRANFIELD UNIVERSITY;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;TURUN YLIOPISTO;UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK";"AT;DE;LT;CH;IT;ES;SE;UK;FR;FI;IE";"/EDU;/NET";1;0;0;2;0;0 186937;631883;NULTIS;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-CIG;FP7;Next generation ultrafast continuously running imaging system for biomedical applications;2014-07-01;2018-06-30;;"'Ultrafast continuously running cameras are a vital tool in capturing and visualizing ultrafast non-repetitive events, such as chemical dynamics, microfluidics, and laser nuclear fusion. Following active involvement in the successful development of the world’s fastest continuously running camera over the last two years, the applicant proposes to develop the next generation ultrafast imaging systems and to apply the developed systems in interdisciplinary scientific research. This research has two main objectives: 1. To develop the next generation ultrafast (~100 Mfps) imaging systems with new capabilities, such as phase-contrast imaging, Raman scattering detection, on-chip integration and with significantly enhanced spatial resolution. 2. To apply the developed instruments in biomedical research. The proposed research builds on the applicant's extensive expertise in photonics and electronics with a good track record of collaboration with researchers from different disciplines. To develop the next generation ultrafast imaging system, original and innovative techniques will be utilized. For instance, by incorporating a Michelson interferometer into the imaging optics, phase-contrast imaging capability will be created. Real-time Raman-spectroscopy-based imaging will be achieved by mirroring the Raman spectrum to a temporal waveform and applying distributed Raman amplification. Photonic integrated circuits (PIC) technology will be used to develop an integrated on-chip imaging system. Physical implementation of the system in shorter wavelength region and applying a compressive sampling algorithm will greatly improve spatial resolution. Furthermore, combining with microfluidic chips, next generation flow microscope system will be developed for high-throughput screening of rare cancer cells in blood. The technique developed will provide an indispensable tool for significant advancements in interdisciplinary research where high-throughput imaging instruments are essential.'";100000;100000;FP7-PEOPLE-2013-CIG;/MC-CIG;UNIVERSITY OF KENT;UK;;;/LIF;1;0;0;2;0;0 95592;255961;QCS;CLO;FP7-ICT;ICT-2009.8.0;FP7;Quantum Computer Science;2010-09-01;2013-08-31;;"Quantum Information Science (QIS) is a young, highly interdisciplinary field touching on the foundations of both computer science and quantum physics It provides a new model of computation that is both physically feasible and more powerful than conventional computing. If a quantum computer is built, we will be able to solve computational problems that are hard for ordinary computers. Quantum information also enables communication and cryptography protocols that are impossible in the classical world. These facts have created enormous interest in QIS.
We propose research on computer science aspects of QIS, with a strong interdisciplinary collaboration between computer scientists and physicists that makes our consortium unique in Europe. We will apply ideas from computer science to solve problems in quantum information science and the ideas from quantum information and physics to solve problems in classical computer science.
Our goals include new methods for building quantum algorithms (e.g., by harnessing quantumwalks) and understanding the general structure of quantum algorithms (e.g., the interplay between their quantum and classical components). In quantum communication, we will integrate the computer science and physics perspectives, with implications for a variety of models: quantum games, communication complexity, interactive proofs and cryptographic protocols.
We will also study the mathematical structures that are common to classical and quantum computing, with applications to both fields.
We believe that our approach is the most timely answer to:A) the challenges presently facing the theory of QIS which needs both a strengthening of its foundations and the development of new applications; andB) the exciting but as yet barely explored opportunity of applying the new tools developpedwithin QIS to classical computer science.";2212227;1679870;FP7-ICT-2009-C;/CP;LATVIJAS UNIVERSITATE;LV;"THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;UNIVERSITE PARIS DIDEROT - PARIS 7;STICHTING CENTRUM VOOR WISKUNDE EN INFORMATICA;FUNDACIO INSTITUT DE CIENCIES FOTONIQUES;UNIVERSITE PARIS-SUD;UNIVERSITE LIBRE DE BRUXELLES;TEL AVIV UNIVERSITY;UNIVERSITY OF BRISTOL ROYAL CHARTER;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS";"UK;FR;NL;ES;BE;IL";"/SCI;/ITT";1;0;0;2;0;0 95593;257626;ACROPOLIS;CLO;FP7-ICT;ICT-2009.1.1;FP7;Advanced coexistence technologies for radio optimisation in licensed and unlicensed spectrum;2010-10-01;2013-12-31;;"Wireless communications, perpetually a source of innovation, is entering new and uncharted territory. In order to enhance system performance and cater for the services and applications of the future, there is the need for cooperative and cognitive communications paradigms that support advanced coexistence technologies for radio optimization. In short, wireless communications is moving towards a disruptive phase, where the speed and capability of interdisciplinary knowledge integration, for systems cooperation and coexistence, becomes a requirement for survival. This needs new thinking, and the development of architectures and facilitators for novel flexible radio technologies. To account for this paradigm shift and position Europe to benefit most from it, experts in areas of cooperation and coexistence, comprising but not limited to realms such as cognitive radio, cognitive networking and flexible networking, must integrate and harmonize their agendas. Through this approach, to paraphrase a common adage, 'the whole will become stronger than the sum of the parts'. Moreover, there is the need to produce a next generation of European researchers, with the right skills-sets to solve the challenges of optimisation for cooperative and coexisting wireless systems. The ACROPOLIS NoE is specifically designed to meet these challenges; it has a strong, interdisciplinary, joint-research agenda, fostering rapid innovation that is of the highest quality and is able to bridge the gaps in European research. Its structure allows it to react rapidly to changes in the research landscape, where integration of research activities to achieve critical mass, and spreading of excellence throughout industry, other research organisations and elsewhere, are at the very heart of its formulation and ideals. To summarise, ACROPOLIS fosters relevant European excellence in research and education, and through the amalgamation of this strives to achieve new heights that would otherwise be impossible.";4147062;3000000;FP7-ICT-2009-5;/NoE;KING'S COLLEGE LONDON;UK;"POLITECHNIKA POZNANSKA;KUNGLIGA TEKNISKA HOEGSKOLAN;WROCLAWSKIE CENTRUM BADAN EIT+ SPZOO;CENTRE TECNOLOGIC DE TELECOMUNICACIONS DE CATALUNYA;RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN;INSTITUTE OF ACCELERATING SYSTEMS AND APPLICATIONS;AIRBUS DEFENCE AND SPACE GMBH;UNIVERSITY OF LEEDS;UNIVERSITY OF PIRAEUS RESEARCH CENTER;EURECOM;UNIVERSITY OF SURREY;UNIVERSITA DEGLI STUDI DI ROMA LA SAPIENZA;Ss. CYRIL AND METHODIUS UNIVERSITY IN SKOPJE;TECHNISCHE UNIVERSITAET DRESDEN;JRC -JOINT RESEARCH CENTRE- EUROPEAN COMMISSION";"PL;SE;ES;DE;EL;UK;FR;IT;MK;BE";/NET;1;0;0;2;0;0 95512;258063;HC2;CLO;FP7-ICT;ICT-2009.8.9;FP7;Human Computer Confluence Research in Action;2010-10-01;2013-09-30;;HCC, Human-Computer Confluence, is an ambitious research program studying how the emerging symbiotic relation between humans and computing devices can enable radically new forms of sensing, perception, interaction, and understanding. The horizontal character of HCC makes it a fascinating and fertile interdisciplinary field, but it can also compromise its growth, with researchers scattered across disciplines and groups worldwide. A coordination activity promoting discipline connect, identity building and integration while defining future research, education and policy directions is needed at the regional, national, European and international level. The goals of HC2 are: 1) to stimulate, structure and support the research community, promoting identity building, 2) to consolidate research agendas with special attention to the interdisciplinary aspects of HCC, producing useful visions and roadmaps to support future research 3) enhance the Public Understanding of HCC and foster the early contact of researchers with high-tech SMEs and other industry players 4) establish guidelines for the definition of new educational curricula to prepare the next generation of HCC researchers.;577561;490000;FP7-ICT-2009-5;/CSA;STARLAB BARCELONA SL;ES;"INSTITUT DE RECHERCHE ET DE COORDINATION ACOUSTIQUE MUSIQUE - IRCAM;UNIVERSITAT LINZ;UNIVERSITA CATTOLICA DEL SACRO CUORE";"FR;AT;IT";/ICT;1;0;0;2;0;0 85727;214668;ITALK;CLO;FP7-ICT;ICT-2007.2.1;FP7;Integration and Transfer of Action and Language Knowledge in Robots;2008-03-01;2012-02-29;;The ITALK project aims to develop artificial embodied agents able to acquire complex behavioural, cognitive, and linguistic skills through individual and social learning. This will be achieved through the development of cognitive robotic agents, such as the iCub humanoid platform, that learn to handle and manipulate objects and tools autonomously, to cooperate and communicate with other robots and humans, and to adapt their abilities to changing internal, environmental, and social conditions.
The main theoretical hypothesis behind the project is that the parallel development of action, conceptualisation and social interaction permits the bootstrapping of language capabilities, which on their part enhance cognitive development. This is possible through the integration and transfer of knowledge and cognitive processes involved in sensorimotor learning and the construction of action categories, imitation and other forms of social learning, the acquisition of grounded conceptual representations and the development of the grammatical structure of language.
The project will lead to the development of: (a) new theoretical insights, models and scientific explanations of the integration of action, social and linguistic skills and in particular on the hypothesis that action, social and linguistic knowledge co-develop and further bootstrap cognitive development, (b) new interdisciplinary sets of methods for analysing the interaction of language, action and cognition in humans and artificial cognitive agents, (c) new cognitively-plausible engineering principles and approaches for the design of robots with behavioural, cognitive, social and linguistic skills.
Overall, the project proposes visionary research that will provide a new standard in embodied cognitive science and will demonstrate the effectiveness of the method proposed by integrating interdisciplinary theoretical and experimental research on a single advanced robotic platform.;8163635;6250000;FP7-ICT-2007-1;/CP;UNIVERSITY OF PLYMOUTH;UK;"THE UNIVERSITY OF HERTFORDSHIRE HIGHER EDUCATION CORPORATION;RIKEN THE INSTITUTE OF PHYSICAL AND CHEMICAL RESEARCH;FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA;CONSIGLIO NAZIONALE DELLE RICERCHE;SYDDANSK UNIVERSITET;UNIVERSITAET BIELEFELD";"UK;JP;IT;DK;DE";"/ROB;/ELM;/ICT;/IPS;/TEL";1;0;0;2;0;0 111195;619241;EYE;CLO;FP7-ICT;ICT-2013.9.1;FP7;Empowering Young Explorers;2013-11-01;2014-10-31;;"Young researchers working in future and emerging technologies (FET) are critical to the success of strategically important areas of science and technology in Europe. However, to realise their full potential as individuals and as a collective resource, they need to optimise their capacity and capability to generate and realise breakthrough ideas and research. The aim of the EYE project is to build a lasting European community of high potential young researchers (YRs) that are able to generate radical new ideas and build research collaborations in interdisciplinary areas, EYE will help them to develop their research potential and their ability to develop new curricula for FET. Specifically, EYE focuses on (a) S&T ideas of higher risk nature that can be generated through ideation and brainstorming and (b) collaboration between YRs across various disciplines and from different parts of Europe, and (c) on the YRs themselves, by developing their leadership potential through networking and training in the specific methods used in European collaborative projects.EYE will achieve its goal by implementing an integrated programme of complementary regional and European events:(a) 'Lab Surfing' workshops in 6 regions of Europe that inform YRs about the most advanced FET research across various disciplines, brainstorm future paradigms and enhance YRs' scientific administration skills;(b) Europe-wide 'Blue Sky' Conferences for YRs in 38 countries in Europe (EU members states and selected countries associated with FP7) to enable further consolidation of ideas at a European level and wider networking with academia, industry and policy makers;(c) 'Science Incubator' Summer Schools to assist selected YRs in bringing their ideas to a position where they might form the basis of future FET project proposals.EYE will conduct two rounds of these events over 2 years in order to reach a wider group of YRs in Europe and to ensure the sustainability of the EYE action after the end of the project. The EYE activities are supported with an online platform (NOVA-Networking for Outstanding Visionaries & Academics) which serves as an operational tool to prepare the events and as a professional platform for ideation, networking, collaboration and discussion amongst YRs.The project's thematic scope is broadly defined by 9 multidisciplinary research areas identified in the recent public consultation on future FET, as well as Horizon 2020 societal challenges. In particular, EYE will seek areas where Information and Communication Technologies (ICT) can bring new interdisciplinary research opportunities and will support both curiosity- and agenda-driven research. The project brings together a broad representation of the multidisciplinary research community in Europe with 11 participants from 9 countries including 7 universities, 2 strong research institutions, and 2 SMEs.";1337150;1152960;FP7-ICT-2013-C;/CSA;TECHNISCHE UNIVERSITEIT DELFT;NL;"EUROPLAN UK LTD;UNIVERSITE DE LORRAINE;THE UNIVERSITY OF MANCHESTER;INSTITUTE OF INFORMATION AND COMMUNICATION TECHNOLOGIES;UNIVERSITAET LEIPZIG;ELEKTROTEHNICKI FAKULTET UNIVERZITET U BEOGRADU;INSTITUTO TECNOLOGICO DE INFORMATICA;ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA;PREDUZECE ZA TURISTICKE USLUGE I TRGOVINU OMEGA TRAVEL DOO;CHALMERS TEKNISKA HOEGSKOLA AB";"UK;FR;BG;DE;RS;ES;IT;SE";/INF;1;0;0;2;0;0 89967;230814;IMAPLA;ONG;FP7-PEOPLE;FP7-PEOPLE-IRSES-2008;FP7;Integrated Maintenance Planning;2009-01-01;2013-06-30;;"It is commonly recognized that maintenance management of industrial plants is an interdisciplinary topic. Design and improvement of maintenance management systems can be achieved only by considering all together different interconnected methodologies and technologies. When building a maintenance management system, one should deserve attention to multiple and heterogeneous issues, such as, e.g.: the ICT tools and platforms for maintenance and plant automation; machine diagnostics and prognostics; maintenance economics and planning, maintenance human resources, spare parts, etc… Due to the above mentioned situation, an international interdisciplinary working group, endorsed by well recognized scientific institutions, can be considered very important to overcome the “divide” situation among maintenance related disciplines and, in particular, to bring together, in the context of a collaborative scheme of research exchanges, the reciprocal knowledge. This project proposal is endorsed by four institutions, 3 EU partners and a Chilean partner, agreeing for a common exchange program built around the theme of Integrated Maintenance Planning (iMaPla). The exchange program aims to facilitate deployment of a collaborative scheme focused on the exchange of the knowledge required to develop methods, models, ICT tools for Integrated Maintenance Planning. The knowledge is provided complementarily by the members of the project consortium. The complementarities have been drawn out in accordance to a joint research vision, commonly shared by the partners at the moment of writing the proposal. The project will concern the exchange activities of PhD students, researchers and professors. The exchanges will enable the reciprocal transfer of knowledge between the members of the consortium and will be deployed by a set of various activities (integrated exchange programs, training in laboratories, lectures exchange program, workshops / seminars open also to external stakeholders).";163800;163800;FP7-PEOPLE-IRSES-2008;/MC-IRSES;POLITECNICO DI MILANO;IT;;;/EDU;1;0;0;2;0;0 109497;607139;ICARE;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-ITN;FP7;Improving Children's Auditory Rehabilitation;2014-01-01;2017-12-31;;"Improving Children’s Auditory REhabilitation (iCARE) Communication through language is vital to develop and maintain everything around us. By 15 years of age, about 5 out of 1000 children suffer from a moderate, severe or profound hearing impairment that can potentially affect communication, learning, psychosocial development and academic achievement if not appropriately handled. The EU promotes the active inclusion and full participation of disabled people in society. However, full active inclusion in an oral society can only be achieved through cooperation and involvement across disciplines (language, psychology, audiology, engineering, special education,…). It is therefore of fundamental importance to approach the inclusion of children with hearing impairment in an interdisciplinary manner, and to train future experts to adopt such principles in their research and practice. The objectives of improving Children’s Auditory REhabilitation (iCARE) are twofold: 1) to provide training create a new generation of researchers capable of exploiting the synergies between different disciplines to optimize spoken communication in children with hearing impairment, and 2) to combine research across disciplines to develop novel methods, training skills and procedures for improving auditory rehabilitation. iCARE is an international and interdisciplinary consortium from academia, industry and socio-economic agencies. The proposed training consortium is unique because the partners are specialized in a variety of disciplines, both technical and non-technical, all of utmost importance to the core issue: optimizing inclusion of children with hearing impairment in an oral society through evidence-based research. The consortium will provide comprehensive training of fellows to become ‘communication experts’, and enable the development of novel methods, tools and evaluation material that will suit the evolving needs of children with hearing impairment in a holistic manner.";4085629,23;4085629,23;FP7-PEOPLE-2013-ITN;/MC-ITN;KATHOLIEKE UNIVERSITEIT LEUVEN;BE;"UNIVERSITY OF MACEDONIA;LINKOPINGS UNIVERSITET;NOLDUS INFORMATION TECHNOLOGY BV;STICHTING KATHOLIEKE UNIVERSITEIT;RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN;Centre for Musculoskeletal Research - University of Gävle;UNIVERSITY COLLEGE LONDON;COCHLEAR RESEARCH AND DEVELOPMENT LIMITED";"EL;SE;NL;DE;UK";/LIF;1;0;0;2;0;0 100568;274580;OnCoA;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-IOF;FP7;Online Communication Analysis: Methods for Multimodal, Networked Communication;2011-09-01;2013-08-31;;"The overarching objective of the proposed project “Online Communication Analysis: Methods for Multimodal, Networked Communication” (OnCoA) is to develop an interdisciplinary methodological and theoretical approach to online communication in the field of media and communication studies that aims to provide applicable solutions for current and future demands in digital media and communication analysis. The term ‘online communication’ comprises here any communicative interaction/action on and by means of the Internet. Therefore, the project focuses on methods and underlying theories/paradigms regarding the analysis of multimodal, networked online communication where text, audio, pictures and video represent different albeit joined linguistic modes that build coherent content. Hyperlinks represent another linguistic mode that turns static and linear text into dynamic networked communication where both the text producers and readers become interchangeable actors. The innovative nature of the project lies in its interdisciplinarity, aiming at an integration of both social sciences-driven and media informatics-driven approaches in online communication research. The methodological, theoretical, and technological challenges of this research arise out of the multimodal nature of digital communication (e.g. websites or weblogs with text, audio, and video content). Additionally, the multitude and networked (i.e. hyperlinked) nature of online communication demand a revision and amplification of existing approaches to online communication analysis, specifically regarding the traditional methods in social sciences, such as content analysis.";141148,4;141148,4;FP7-PEOPLE-2010-IOF;/MC-IOF;UNIVERSITY COLLEGE LONDON;UK;TECHNISCHE UNIVERSITAET ILMENAU;DE;"/EMP;/SOC;/COO";1;0;0;2;0;0 92340;236950;TSPAASPMPG;ONG;FP7-PEOPLE;FP7-PEOPLE-IEF-2008;FP7;The slide of Punishment. An anthropological study of Post-Modern prison governance;2010-02-01;2012-01-31;;Developing an interdisciplinary approach between Criminology, Social control theories and Anthropology, the project contributes a new theoretical framework for the analysis of punitive transformation in Europe. It analyses mechanisms and devices of a new model of penal management in the spanish prison system and compares it to relevant data from german and european research projects. The new penal management model has been conceptualized by the researcher as Therapeutic governance. This concept serves to describe the institutional strategies, disciplinary actions and rhetoric orders through which the prison allows to legitimate a new punitive era. Assuming that prison governance is significant for society as a whole the research will analyse control technologies exerted in the prison spaces and how they slide into public dynamics through different agencies. Consecuently another new concept, the Punitive Agora, will be developed. This concept puts under discussion and theorizes three current tendencies of postmodern penality: the download of responsibility for crime control into the community, the emergence of a penal populism rhetoric and the discriminatory criminalization of specific groups. Comparing its findings with studies produced in Germany, Europe and beyond, the project will enable to take up important questions of contemporary governance. Thus, it will allow to consolidate the researcher’s career as an international specialist in the field of Anthropology and Criminology. He will develop and apply new tools for interdisciplinary and comparative analysis and increase his competitiveness in academia. The researcher’s capacity to stimulate collaborations between international departments and research groups will be reinforced. Finally, the project will allow to enhance collaborations between european research partners and to produce high-level european scientific synergies.;;161119,38;FP7-PEOPLE-IEF-2008;/MC-IEF;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;DE;;;"/SCI;/EMP";1;0;0;2;0;0 92472;235065;ROBOT-DOC;ONG;FP7-PEOPLE;FP7-PEOPLE-ITN-2008;FP7;ROBOTics for Development Of Cognition;2009-09-15;2014-09-14;;"The ROBOT-DOC proposal aims at the establishment of a multi-national doctoral training network for the interdisciplinary training on developmental cognitive robotics. Developmental robotics is a novel approach to the design of robots that takes direct inspiration from the developmental mechanisms studied in children by psychologists and cognitive neuroscientists. The Fellows will develop advanced expertise of domain-specific robotics research skills and of complementary transferable skills for careers in academia and industry. They will acquire hands-on experience through experiments with the open-source humanoid robot iCub, complemented by other existing robots available in the network’s laboratories. The hardware and software of iCub is just becoming available, so ROBOT-DOC provides an excellent one-off timely opportunity to make real international progress in Europe by training a critical mass of researchers. Research training will be centred on a series of training milestones such as two summer schools, international conferences and interdisciplinary research methods workshops. Fellows will also be directly involved and closely supervised for research in novel projects on embodied cognition, motivational and affective mechanisms, neuro-robotics modelling, developmental psychology, sensorimotor learning, social interaction and higher-order cognitive modelling. An individual coaching programme will support each Fellow’s training progress as well as professional and personal enhancement through individualised skill development plans. The ROBOT-DOC network consists of an excellent balance of academic and industrial partners, and of European and international laboratory leaders in developmental cognitive robotics. The network activities will have a significant impact on the career perspectives of the Fellows through training opportunities on industrial and academic research projects and skills. The network will contribute to the enhancement of the European R&D interd";3492830;3492830;FP7-PEOPLE-ITN-2008;/MC-ITN;UNIVERSITY OF PLYMOUTH;UK;"UNIVERSITAET HAMBURG;UPPSALA UNIVERSITET;UNIVERSITAT ZURICH;FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA;HOGSKOLAN I SKOVDE;TELEROBOT OCEM;UNIVERSITAET BIELEFELD;TELEROBOT SPA";"DE;SE;CH;IT";"/SCI;/EDU";1;0;0;2;0;0 89667;215503;NSINK;ONG;FP7-PEOPLE;PEOPLE-2007-1-1-ITN;FP7;Training in sources, sinks and impacts of atmospheric nitrogen deposition in the Arctic;2008-11-01;2012-10-31;;The NSINK Initial Stage Network training network targets one of the most vital, interdisciplinary problems facing future Arctic environmental management: namely the enrichment of Arctic terrestrial and aquatic ecosystems by reactive atmospheric nitrogen from low latitude emission centres. This problem will greatly exacerbate ecosystem response to climate change, and urgently requires holistic, sources to sinks type studies of nitrogen dynamics. Thus training in atmospheric sciences, snow physics, hydrology, biogeochemistry and aquatic/terrestrial ecology is necessary, bringing UK, Norwegian, Swedish, Austrian and German expertise (already operative in Svalbard) into a single interdisciplinary project at Ny ?lesund, the site of Europe’s most significant high Arctic environmental monitoring infrastructure. Further, in order to constrain recent change in the nitrogen accumulation in this environment, training in the interpretation of ice core and lake sediment archives will also be offered, and a reanalysis of instrumental observations collected over the last 15 years will be undertaken. NSINK will therefore prepare talented researchers for careers as independent scientists/practitioners across a range of environmental sciences (e.g. biogeochemistry, atmospheric sciences, hydrology) and related sectors either in academia or in industry. The scale of the NSINK ITN is significant (nine Early Stage Researchers, three Experienced Researchers, four training partners and 9 associated or industrial partners) because it addresses the demand for training in this area resulting from the urgent science problem and a major growth in public interest in the environmental sciences that is being experienced by universities across the entire EU.;2656767;2656767;FP7-PEOPLE-2007-1-1-ITN;/MC-ITN;UNIVERSITY OF SHEFFIELD ROYAL CHARTER;UK;"UPPSALA UNIVERSITET;NORSK POLARINSTITUTT;UNIVERSITAET INNSBRUCK;NATURAL ENVIRONMENT RESEARCH COUNCIL";"SE;NO;AT;UK";"/EMP;/SOC;/EDU";1;0;0;2;0;0 104873;316746;PRISM;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-ITN;FP7;"""Perceptual Representation of Illumination, Shape and Material""";2013-01-01;2016-12-31;;'Visual perception provides us with a richly detailed representation of the surrounding world, enabling us to make subtle judgements of 1) 3D shape, 2) the material properties of objects, and 3) the flow of illumination within a scene. Together, these three factors determine the intensity of a surface in the image. Estimating scene properties is crucial for guiding action and making decisions like whether food is edible. Visual ‘look and feel’ also plays a key role in industrial design, computer graphics and other industries. Despite this, little is known about how we visually estimate the physical properties of objects and illumination. Previous research has mainly focussed on one or two of the three causal factors independently, and from the viewpoint of a specific discipline. By contrast, in PRISM we take an integrative approach, to understand how the brain creates a richly detailed representation of the world by looking at how all three factors interact simultaneously. PRISM is radically interdisciplinary, uniting experts from psychology, neuroscience, computer science and physics to understand both the analysis and synthesis of shape, shading and materials. PRISM is intersectoral by uniting researchers from seven leading Universities and two industrial partners, enabling impact in basic research, technology and the creative industries. Through research projects, cross-discipline visits, and structured Course Modules delivered through local and network-wide training events, we will endow PRISM fellows with an unusually broad overview and the cross-sector skills they need to become future leaders in European research and development. Thus, by delivering early-career training embedded in a cutting-edge research programme, we aim to 1) springboard the next generation of interdisciplinary researchers on perceptual representations of 3D scenes and 2) cement long-term collaborations between sectors to enhance European perception research and its applications.';3014865,92;3014865,92;FP7-PEOPLE-2012-ITN;/MC-ITN;JUSTUS-LIEBIG-UNIVERSITAET GIESSEN;DE;"INSTITUT NATIONAL DE RECHERCHE ENINFORMATIQUE ET AUTOMATIQUE;THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;THE UNIVERSITY OF BIRMINGHAM;NEXT LIMIT SL;BILKENT UNIVERSITESI VAKIF;KATHOLIEKE UNIVERSITEIT LEUVEN;UNIVERSITE PARIS DESCARTES;TECHNISCHE UNIVERSITEIT DELFT";"FR;UK;ES;TR;BE;NL";/LIF;1;0;0;2;0;0 98149;267352;TERAUNIVERSE;ONG;FP7-IDEAS-ERC;ERC-AG-PE2;FP7;Exploring the Terauniverse with the LHC, Astrophysics and Cosmology;2011-04-01;2016-03-31;;The visible matter in the Universe is well described by the Standard Model, but this leaves open major questions in both particle physics and cosmology that may be answered by new physics at the Tera-electron-Volt range: the Terascale. The Large Hadron Collider (LHC) will soon open a new stage in humanity’s direct exploration of the fundamental physical laws at Terascale energies, which governed the evolution of the Universe a fraction of a second after the Big Bang, and are essential for understanding high-energy astrophysics. In addition to unraveling the intimate structure of matter at the Terascale, e.g., by discovering the source of particle masses and exploring matter-antimatter asymmetry, the LHC will address key cosmological issues such as how dark and conventional matter originated, which may well have been at the Terascale, and the nature of the primordial plasma that filled the Universe. This proposal will lead the understanding whatever new physics the LHC may reveal, incorporating insights from cosmology, high-energy astrophysics and speculative ideas such as string theory. This interdisciplinary approach will also facilitate the application of knowledge acquired from the LHC to fundamental cosmological and astrophysical problems, as well as illuminate future collider priorities, e.g., for LHC upgrades and/or a linear collider. This proposal will bring together particle theorists, experimentalists, astroparticle physicists and experts on field and string theory in the framework of a new ‘London Centre for Terauniverse Studies’. This will provide new opportunities for students and other young researchers to get directly involved in making LHC discoveries and exploring their implications for the Universe, and provide a mechanism for transferring to them interdisciplinary skills.;1928700;1928700;ERC-2010-AdG_20100224;/ERC-AG;EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH;CH;"IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE;UNIVERSITY COLLEGE LONDON;KING'S COLLEGE LONDON";UK;"/PSE;/SCI";1;0;0;2;0;0 100631;290100;EDA-EMERGE;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-ITN;FP7;Innovative biodiagnosis meets chemical structure elucidation – Novel tools in effect directed analysis to support the identification and monitoring of emerging toxicants on a European scale;2011-10-01;2015-09-30;;EDA-EMERGE aims to train a new generation of young scientists in the interdisciplinary techniques required to meet the major challenges in the monitoring, assessment and management of toxic pollution in European river basins considering the enormous complexity of contamination, effects and cause-effect relationships. By integrating innovative mode-of-action based biodiagnostic tools including in vitro tests, transgenic organisms and “omics” techniques with powerful fractionation and cutting edge analytical and computational structure elucidation tools, a new generation of effect directed analysis (EDA) approaches will be developed for the identification of toxicants in European surface and drinking waters. Innovative method development by young researchers at major universities, research centres and private companies will be closely interlinked with a joint European demonstration program and higher tier EDA and extensive training courses. EDA-EMERGE ESRs will learn to organise and run international and interdisciplinary sampling and monitoring campaigns and benefit from the expertise of one of the most experienced private companies in this field. Strong networking between academia, the private sector and leading regulators in the field of river basin management and pollution management ensures the relevance of the research for practice and excellent employment opportunities for EDA-EMERGE ESRs. The combination of cutting edge science with training in multiple complementary (soft) skills offered with a strong emphasis on commercial exploitation and media competence will further enhance employability of well-trained ESRs not only in research and academia but far beyond. An internationally composed advisory board will introduce new perspectives of monitoring, assessment and management of emerging pollutants within and outside of Europe.;3751910,8;3751910,8;FP7-PEOPLE-2011-ITN;/MC-ITN;HELMHOLTZ-ZENTRUM FUER UMWELTFORSCHUNG GMBH - UFZ;DE;"KWR WATER B.V.;STICHTING VU;RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN;INSTITUT NATIONAL DE L ENVIRONNEMENT ET DES RISQUES INERIS;VERENIGING VOOR CHRISTELIJK HOGER ONDERWIJS WETENSCHAPPELIJK ONDERZOEK EN PATIENTENZORG;EIDGENOESSISCHE ANSTALT FUER WASSERVERSORGUNG ABWASSERREINIGUNG UND GEWAESSERSCHUTZ;NORSK INSTITUTT FOR VANNFORSKNING;WATCHFROG;ENVIRONMENTAL INSTITUTE s.r.o.;RUDER BOSKOVIC INSTITUTE";"NL;DE;FR;CH;NO;SK;HR";"/LIF;/SCI";1;0;0;2;0;0 99016;269484;INTERACT;ONG;FP7-IDEAS-ERC;ERC-AG-SH4;FP7;The Interaction Engine: Interactive foundations for communication;2011-06-01;2016-09-30;;"This project addresses a serious gap at the heart of the social and cognitive sciences. The proposal is to fast-start an interdisciplinary science of human communicative interaction focused on sequences of contingent actions. The research will be guided by a novel hypothesis, the ‘interaction engine’, which holds that human interactive abilities are distinct from and phylogenetically older than our language capacity. Inverting the usual assumptions, the hypothesis suggests that the human interaction system is fundamentally universal, while the language system lacks substantial universals and is diversified by cultural evolution. The interaction system and language system therefore do not mesh neatly, and this can be detected in the domain of contingent action sequences – the crucial characteristic of human interaction. Two specific areas, (a) the timing of turn-taking and (b) the ascription of speech acts or intentions, will be examined from three distinct disciplinary perspectives: (i) cross-cultural corpus and experimental studies in a dozen languages, (ii) developmental studies (corpus and experiment based) from early infancy up to middle childhood, (iii) cognitive studies employing both behavioural measures (reaction time, eye tracking), and neurocognitive methods (EEG, fMRI). The ‘interaction engine’ hypothesis makes detailed predictions about cross-cultural universals, developmental trajectories, and processing complexities in both turn-taking and action ascription. The project aims to build an integrated, interdisciplinary science of communicative interaction. New developments (multi-media corpora, dual eye-tracking, EEG, fMRI, baby-lab techniques) now make this feasible. The PI and host institution are uniquely equipped to undertake this project.";2495400;2495400;ERC-2010-AdG_20100407;/ERC-AG;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;DE;;;/MED;1;0;0;2;0;0 92709;238214;C7;ONG;FP7-PEOPLE;FP7-PEOPLE-ITN-2008;FP7;Cerebellar-Cortical Control: Cells, Circuits, Computation, and Clinic;2009-11-01;2013-10-31;;A functional understanding of the cerebellum, the structure of the human brain with the most neurons, requires the combined effort of scientists working from the cellular level up to the behavioural level, and it requires scientists trained to cross these levels. The C7 network brings together 9 research groups to form a European institute for the interdisciplinary study of the cerebellum. The network will provide a unique multi-disciplinary training experience for young researchers in systems neuroscience. We are joined by 5 industrial partners who will help to realize important technological innovations and the commercial potential by developing cutting-edge technology for research and clinical applications. With a combination of electrophysiology, behavioural and clinical research, computational modelling and neuroimaging we will aim to answer three important questions: a) What is the computation performed in cerebellar networks? We will provide a multi-level description of the basic cerebellar computational unit, the micro-column. b) How do distributed synaptic changes lead to learning? We link structure to function through an intense program of experimentation and modelling on the fast adaptation of motor behaviour thought by many to be the main function of the cerebellum. c) How do the closed loops between the cerebellum and neocortex generate motor control and cognition? Multi-site recordings, TMS and clinical studies will reveal the previously unexplored interaction between cerebellum and related structures. C7 includes two clinical research centres and two patient organizations, promoting the transfer of insights from basic science to clinical practice. In particular, we will explore brain compensation following cerebellar dysfunction using genetic mouse models and TMS. In sum, C7 will provide the interdisciplinary training environment necessary for a new understanding of the cerebellum.;3662669,5;3662669,5;FP7-PEOPLE-ITN-2008;/MC-ITN;UNIVERSITY COLLEGE LONDON;UK;"UNIVERSITEIT ANTWERPEN;Alpha Omega Engineering Ltd.;KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW;THE UNIVERSITY OF BIRMINGHAM;BEN-GURION UNIVERSITY OF THE NEGEV;UNIVERSITAETSKLINIKUM ESSEN;ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM;EBERHARD KARLS UNIVERSITAET TUEBINGEN";"BE;IL;NL;UK;DE";"/SCI;/EDU";1;0;0;2;0;0 105058;317205;SEWPROF;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-ITN;FP7;A new paradigm in drug use and human health risk assessment: Sewage profiling at the community level;2012-10-01;2016-09-30;;SEWPROF aims to develop inter-disciplinary and cross-sectoral research capability for the next generation of scientists working in the newly-emerging field of sewage epidemiology. It will provide an integrated approach towards public health monitoring at a community level based on innovative sewage epidemiology techniques. The approach will deliver real-time profiling of community-wide health and lifestyle through the analysis of human biomarkers in sewage using a wide-range of methods including hyphenated mass spectrometry techniques, bioanalytical techniques and real-time sensing. The innovative research strategy of obtaining epidemiological information from sewage has been pioneered by members of the SEWPROF team, and, although still in its infancy, is currently used to determine illicit drug use trends at community level via the analysis of urinary biomarkers in sewage. SEWPROF aims to advance knowledge of the epidemiology of (illicit) drug use and to bridge gaps in the available expertise with the ultimate goal of applying this cutting edge interdisciplinary approach within epidemiological studies of societal health. This conceptually simple but methodologically sophisticated epidemiological approach could become an early warning system for outbreaks of disease and a unique tool for the identification of hot-spots for pandemics. This will be achieved through bringing together leaders in the field across Europe in academia, research institutes and the private sector and utilising their expertise and commitment in training a highly employable cohort of researchers who will acquire advanced knowledge in the field through an interdisciplinary and cross-sectoral training programme delivered by world class research-led organisations and industrial partners.;4178231,27;4178231,27;FP7-PEOPLE-2012-ITN;/MC-ITN;UNIVERSITY OF BATH;UK;"KWR WATER B.V.;UNIVERSITAT JAUME I DE CASTELLON;UNIVERSITEIT ANTWERPEN;ISTITUTO DI RICERCHE FARMACOLOGICHE MARIO NEGRI;EIDGENOESSISCHE ANSTALT FUER WASSERVERSORGUNG ABWASSERREINIGUNG UND GEWAESSERSCHUTZ;UNIVERSITETET I OSLO;DANMARKS TEKNISKE UNIVERSITET;NORSK INSTITUTT FOR VANNFORSKNING;TICTAC COMMUNICATIONS LIMITED;UNIVERSITAT DES SAARLANDES";"NL;ES;BE;IT;CH;NO;DK;UK;DE";/LIF;1;0;0;2;0;0 86619;224460;WISEBED;CLO;FP7-ICT;ICT-2007.1.6;FP7;Wireless Sensor Network Testbeds;2008-06-01;2011-05-31;;"The aim of this project is to provide a multi-level infrastracture of interconnected testbeds of large-scale wireless sensor networks for research purposes, pursuing an interdisciplinary
approach that integrates the aspects of hardware, software, algorithms, and data. This will demonstrate how heterogeneous small-scale devices and testbeds can be brought together to form well-organized, large-scale structures, rather than just some large network; it will allow research not only at a much larger scale, but also in different quality, due to heterogeneous structure and the ability to deal with dynamic scenarios, both in membership and location.
For the interdisciplinary area of wireless sensor networks, establishing the foundations of distributed, interconnected testbeds for an integrated approach to hardware, software, algorithms, and data will allow a new quality of practical and theoretical collaboration, possibly marking a turning point from individual, hand-tailored solutions to large-scale, integrated ones.
For this end, we will engage in implementing recent theoretical results on algorithms, mechanisms and protocols and transform them into software. We will apply the resulting code to the scrutiny of large-scale simulations and experiments, from which we expect to obtain valuable feedback and derive further requirements, orientations and inputs for the long-term research. We intend to make these distributed laboratories available to the European scientific community, so that other research groups will take advantage of the federated infrastructure.
Overall, this means pushing the new paradigm of distributed, self-organizing structures to a different level.";3629188;2769890;FP7-ICT-2007-2;/CP;UNIVERSITAT ZU LUBECK;DE;"UNIVERSITE DE GENEVE;UNIVERSITAET BERN;TECHNISCHE UNIVERSITAET BRAUNSCHWEIG;UNIVERSITAT POLITECNICA DE CATALUNYA;LANCASTER UNIVERSITY;FREIE UNIVERSITAET BERLIN;INSTITOUTO TECHNOLOGIAS YPOLOGISTONKAI EKDOSEON DIOFANTOS;TECHNISCHE UNIVERSITEIT DELFT";"CH;DE;ES;UK;EL;NL";"/ELM;/IPS;/TEL";1;0;0;2;0;0 88974;215851;HIERARCHY;ONG;FP7-PEOPLE;PEOPLE-2007-1-1-ITN;FP7;Hierarchical Assembly in Controllable Matrices;2008-11-01;2012-10-31;;The mission of HIERARCHY is to train and educate young scientist in the rapidly developing field of nanosciences, in particular hierarchical self-assembly. The training programme educates early stage and experienced researches in many aspects of this highly interdisciplinary field, such as theory, materials chemistry and biochemistry, advanced characterisation techniques, physics and commercial device development. In addition, the training programme will address non-scientific issues, important for the career development of young scientists, e.g. communication and presentation skills, IPR and entrepreneurial skills, ethical issues, language enhancement and cultural awareness. The training takes place on a Network level and also locally at the host institutions. HIERARCHY’s training programme will deliver versatile individuals with a broad scientific knowledge, ready to pursue a successful career in the European industry or academia. The interdisciplinary research training is centralised around the novel concept of hierarchical assembly in controllable matrices. This concept exploits liquid crystalline media as controllable matrices for programmed self-organisation, which goes far beyond the possibilities of currently employed techniques. A liquid crystal matrix in combination with a variety of simultaneously or sequentially applied external stimuli will yield a unique toolbox to build functional macroscopic structures with nanometer control. Leading European laboratories in soft condensed matter and solid state matter will work towards new paradigms in nanosciences. HIERARCHY’s intention towards application of the designed structures, illustrated by the presence of three industrial partners in the consortium, is an important step towards commercialisation of nanosciences in Europe. With Europe’s desire to become the major player in the area of nanosciences, valorisation of developed technology is a key lesson for Europe’s new generation of nanoscientists.;4648957;4648957;FP7-PEOPLE-2007-1-1-ITN;/MC-ITN;STICHTING KATHOLIEKE UNIVERSITEIT;NL;"MERCK CHEMICALS LTD;INSTITUT JOZEF STEFAN;RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;BALDER OPTOELEKTRONSKI ELEMENTI INMERILNA TEHNIKA DOO;PHILIPS ELECTRONICS NEDERLAND B.V.;TECHNISCHE UNIVERSITEIT EINDHOVEN;UNIVERZA V LJUBLJANI;STICHTING WAGENINGEN RESEARCH";"UK;SI;DE;NL";"/EMP;/SOC;/EDU";1;0;0;2;0;0 92980;238157;EBRAMUS;ONG;FP7-PEOPLE;FP7-PEOPLE-ITN-2008;FP7;Europe, Brain and Music: New perspectives for stimulating cognitive and sensory processes;2009-12-01;2013-11-30;;EBRAMUS investigates an attractive, promising new research avenue at the intersection of neuroscience, the human sciences and new technologies: can music boost sensory, cognitive and motor development in normal and impaired children and adults? The project will assess this issue in an integrative way by combining behavioural, neurophysiological, neuropsychological and computational methods. Three research topics will cover both basic and clinical research using music in the rehabilitation of various patient populations and the elderly. The 1st topic focuses on the rehabilitation of auditory functions and language deficits, the 2nd focuses on the benefits of music for more general cognitive functions (learning, memory) and the 3d on timing behaviour and the use of music in motor rehabilitation. The overall project will increase our understanding of brain functioning and will have a tremendous impact on clinical and educational applications (developing new diagnostic tools, training and rehabilitation techniques, also leading to industrial developments) and for new music technology for the general public. EBRAMUS will foster strong links among partners at the forefront of this interdisciplinary research area. It provides an invaluable opportunity for young researches to gain state-of-the art knowledge in the field of cognitive neurosciences and interdisciplinary research by benefiting from exchanges within the network, from the offered training program (e.g., topical summer schools/workshops) and the project’s good balance between basic research and clinical approaches. The training will ultimately increase students’ career opportunities, thanks to the network’s academic and industrial partners. EBRAMUS partners present a strong network with common and complementary expertise, thus providing ideal multi-site and multidisciplinary training for young researchers and, more generally, providing the opportunity to considerably strengthen Europe’s position in the field.;2341796;2341796;FP7-PEOPLE-ITN-2008;/MC-ITN;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FR;"UNIVERSITEIT GENT;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;Hanover University of Music & Drama;University of Finance and Managment;UNIVERSITE CHARLES DE GAULLE LILLE3;UNIVERSITE D'AIX MARSEILLE;THE UNIVERSITY OF EDINBURGH";"BE;DE;PL;FR;UK";"/SCI;/EDU";1;0;0;2;0;0 93255;247687;AQUTE;CLO;FP7-ICT;ICT-2009.8.2;FP7;Atomic QUantum TEchnologies;2010-02-01;2013-04-30;;"The overall objectives of the AQUTE project areA) To develop quantum technologies based on atomic, molecular and optical (AMO) systems for* scalable quantum computation;* entanglement-enabled technologies like metrology and sensing.B) To establish and exploit new interdisciplinary connections, coming from AMO physics, but also including concepts and experimental settings of solid state systems, in order to* reinforce interdisciplinary links at the frontiers of quantum information science, and other fields of physics or science in general;* conceive and realize novel hybrid systems that couple in a coherent way physically different quantum degrees of freedom.Obj. A will be pursued along two complementary directions:* a bottom-up approach, where individually trapped atomic particles are combined into elementary general-purpose quantum processors including qubit interconnects;* a top-down approach, where many-particle atomic systems are employed to realize special-purpose quantum processors, for instance quantum simulators.Groundbreaking work in qualitatively new directions is also needed to lay the foundations for the future attainment of scalable fault-tolerant architectures. AQUTE will thus also* investigate new experimental systems that have become available in the laboratory and are of direct relevance for QIFT;* optimize existing and develop novel theoretical concepts for quantum processing.Obj. B connects atomic quantum technologies for QIFT to a wider context, by* exploring hybrid approaches to QIFT beyond AMO physics;* improving connections between QIFT and science in general, following the emergence of a new quantum paradigm at the frontier of nanosciences and information sciences.These research lines determine the structuring of the AQUTE workplan into four deeply interrelated Sub-Projects: Entangling gates and quantum processors, Hybrid quantum systems and interconnects, Quantum Simulators and Quantum Technologies.";9142561;5575000;FP7-ICT-2009-4;/CP;UNIVERSITAET ULM;DE;"AARHUS UNIVERSITET;UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6;TECHNISCHE UNIVERSITAET WIEN;COLLEGE DE FRANCE;LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN;THE UNIVERSITY SYSTEM OF MARYLAND FOUNDATION, INC.;THE UNIVERSITY OF QUEENSLAND;JOHANNES GUTENBERG-UNIVERSITAT MAINZ;IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE;UNIVERSITAT BASEL;PRESIDENT AND FELLOWS OF HARVARD COLLEGE;FUNDACIO INSTITUT DE CIENCIES FOTONIQUES;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;UNIVERSITE PARIS-SUD;INSTITUT D'OPTIQUE THEORIQUE ET APPLIQUEE IOTA - SUPOPTIQUE;ECOLE NORMALE SUPERIEURE;RHEINISCHE FRIEDRICH-WILHELMS-UNIVERSITAT BONN;MACQUARIE UNIVERSITY;EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH;NATIONAL UNIVERSITY OF SINGAPORE PUBLIC COMPANY LIMITED BY GUARANTEE;HARVARD GLOBAL RESEARCH AND SUPPORT SERVICES INC.;OESTERREICHISCHE AKADEMIE DER WISSENSCHAFTEN;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;LABORATORIO EUROPEO DI SPETTROSCOPIE NON LINEARI;UNIVERSITAT DES SAARLANDES";"DK;FR;AT;DE;US;AU;UK;CH;ES;SG;IT";/ICT;1;0;0;2;0;0 187744;623183;SMITH;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IEF;FP7;SOCIETY, METALLURGY AND INNOVATION: THE IBERIAN HYPOTHESIS;2014-09-01;2016-08-31;;"The SMITH project seeks to develop our understanding of the origins of metallurgy in Western Europe and its social impact as a starting point to facilitate comparisons on a Eurasian scale It capitalises on unprecedented access to key archaeological materials, availability of synergic projects and infrastructures at UCL, and a wholly interdisciplinary approach that amalgamates cutting edge archaeological science with sophisticated theorisation on the role of technology in society The main questions addressed are: -Whether metallurgy was independently developed in Western Europe -Its actual impact in social stratification processes A wide range of archaeological materials from key sites in Western Europe will be analysed by a myriad of techniques–XRF, SEM, ICP, Metallography, etc–involving interdisciplinary collaboration.The data will be interpreted in the light of the evidence known from Eurasia and especially of the current UCL-lead project on the origins of metallurgy in the Balkans SMITH brings an original perspective as it will refocus the debate on the origins of metallurgy, and because of its comprehensive dual concern: on the one hand it includes all the steps of the metallurgical process (mining, smelting and shaping but also consumption); on the other hand, it approaches metallurgy as part of a myriad of dynamic human activities and relationships in specific and changing social contexts The study of the whole diversity of the archaeometallurgical and archaeological record is anchored in a concern with how societies assimilated metallurgy and developed different metallurgical traditions, and to what extent those processes were influenced by social contacts As a whole, SMITH aims to be on the cutting-edge of existing efforts to produce reliable data and original interpretations on the origins of metallurgy, the transfer of this knowledge and its social impact It will bring to light a wealth of key materials which are likely to challenge current paradigms";221606,4;221606,4;FP7-PEOPLE-2013-IEF;/MC-IEF;UNIVERSITY COLLEGE LONDON;UK;;;;1;0;0;2;0;0 186759;630732;UnZe-IB-DigiHum;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-CIG;FP7;Information Behaviour in Digital Humanities;2014-10-01;2018-09-30;;"This project will provide a unique opportunity for the researcher to return from Australia in his native country, and simultaneously steer his career in a new direction - the emerging research field of digital humanities (DH). DH tools are becoming common components of university environments, promising advanced cyber-infrastructure for future research and teaching in the humanities. However, in order to align DH activities to everyday university settings, we need a better understanding of information behaviour (IB) of scholars and students in these digital environments. The aim of this project is to bring together insights from the fields of IB and DH. The final outcome of the project will be a new model for design of DH applications, informed by an alternative interdisciplinary approach to IB and DH, based on actor-network theory, and by the empirical results of the two in-depth case studies. This will be achieved through a combination of empirical, theoretical, and action research, integrated into the main objectives of the study: 1) to investigate information behaviour in digital humanities activities of scholars and students at the host university; 2) to build a theoretical model for design and management of digital humanities applications, based on theoretical insights from several research fields, and the empirical knowledge gained by the objective 1; and 3) to transfer knowledge to the host through an action research (development of a new DH course and a prototype of a digital textbook for the course) which will also enable an evaluation of the outcomes of the objectives 1 and 2. The project is thus timely and relevant to the efforts of FP7 and the Horizon 2020 to build digital research infrastructure for the humanities, enabling new interdisciplinary ways of research that were not possible in the analogue world.";100000;100000;FP7-PEOPLE-2013-CIG;/MC-CIG;JAVNA USTANOVA UNIVERZITET U ZENICI UNIVERSITAS STUDIORUM ZENICAENSIS;BA;;;/LIF;1;0;0;2;0;0 92269;236020;RECIPROCITY;ONG;FP7-PEOPLE;FP7-PEOPLE-IIF-2008;FP7;Modeling reciprocity in games;2009-09-01;2011-08-31;;"Reciprocity plays an important role in socio-economic interactions as recognized by social scientists in all fields. However, there is no interdisciplinary consensus over the definitions of scientific terms, models, and experimental practices to study it. This project will be an attempt to bring together the best findings and techniques from different fields and create a framework that would allow the possibility to systematically study reciprocal behavior. In the first part of the project the game theoretic model will be constructed. The agents in the model will explicitly take the intentions of others as well as the ownership of the payoffs into account. This is a novel approach never attempted in the existing literature. In the second part, we will define the class of strategic situations to which the model can be sensibly applied. These situations should be naturally understood by people as reciprocal and not competitive. The third part will be dedicated to behavioral experiments intended to demonstrate the validity of the model. The mathematical framework will combine the tools of non-cooperative and cooperative game theory and model agents in the way consistent with the knowledge from psychology and neuroscience. This is an important step towards a single model of human behavior in social sciences, an ultimate goal of interdisciplinary research. The experimental part of the project will show new ways of understanding framing effects, which can influence many applied areas from writing contracts to conducting international politics. The results of the project can provide experimental tests for people's attitudes towards private property, which is a main factor in economic growth. This can contribute to the understanding of, for example, the economic processes in the developing countries. The results can also influence economic policy, for instance, by showing novel ways of testing the strength of preferences over wage inequality.";;151296,49;FP7-PEOPLE-IIF-2008;/MC-IIF;UNIVERSITEIT MAASTRICHT;NL;;;"/SCI;/EMP";1;0;0;2;0;0 109582;607350;LAPASO;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-ITN;FP7;Label Free Particle Sorting;2013-10-01;2017-09-30;;"'LAPASO will provide a unique training opportunity for 15 fellows in a highly interdisciplinary and intersectorial environment with the overarching scientific objective of advancing diagnostics in a wide range of critical medical conditions using advanced microfluidics and nanobiotechnology integration. Microfluidic particle fractionation based on the inherent properties of e.g. cells, microorganisms, organelles offers significant improvements over conventional techniques in terms of ease of handling and usage, speed and reductions in cost. We will consolidate the field at the European level and create a unique comprehensive training program that rests on solid experimental and theoretical foundations. Three leading experimental groups will provide the technological development of microfluidic label-free sorting based on dielectrophoresis, deterministic lateral displacement and acoustophoresis with strong support from leading theorists. The technology will be used to address key medical questions defined by our biomedical collaborators and partners in parasitology, bacteriology and oncology. Three companies are engaged to provide an industrial perspective on our work, specifically from a technological point of view with respect to treatment of infectious disease, advanced fluidics handling and DNA analysis and mass production of devices. To ensure an efficient transfer of knowledge across disciplines and across sectors the work will take place in close collaboration through frequent ESR/ER exchange between the partners. The training of a next generation of researchers will ensure the implementation and dissemination of these powerful novel key techniques to industry and end-users. Through the strong interdisciplinary and intersectorial character of the network, the ESR and ER will receive a uniquely comprehensive training above what a traditional postgraduate training would offer that in turn gives them a strong competitive advantage in both academia and industry.'";4228418,92;4228418,92;FP7-PEOPLE-2013-ITN;/MC-ITN;LUNDS UNIVERSITET;SE;"FORSCHUNGSZENTRUM JULICH GMBH;ELVESYS SAS;MICRONIT MICROTECHNOLOGIES BV;UNIVERSITY OF SOUTHAMPTON;KAROLINSKA INSTITUTET;UNIVERSITY OF GLASGOW;TECHNISCHE UNIVERSITAET DRESDEN";"DE;FR;NL;UK;SE";/LIF;1;0;0;2;0;0 105103;311876;PATHWAY-27;ONG;FP7-KBBE;KBBE.2012.2.2-01;FP7;PIVOTAL ASSESSMENT OF THE EFFECTS OF BIOACTIVES ON HEALTH AND WELLBEING. FROM HUMAN GENOMA TO FOOD INDUSTRY - PATHWAY;2013-02-01;2018-01-31;http://pathway27.eu/;"Scientific understanding of the role and mechanisms of bioactives is fragmented. Research often addresses the theoretical possibility of health improvement effects rather than their real, practical use for everyday diets. Bioactives cannot be considered as discrete chemical compounds and research must focus on bioactive-enriched foods (BEF), if consumer demands for foods delivering appropriate health and wellbeing benefits are to be fulfilled. PATHWAY, a pan-European interdisciplinary team of 16 life/social scientists and 10 high tech/ food processing SMEs, uniquely addresses the role and mechanisms of action of 3 bioactives (docosahexaenoic acid, ?-glucan, anthocyanins, chosen for known/claimed effectiveness in reducing some risk factors of Metabolic Syndrome (MS), enriching 3 different widely-consumed food matrices (dairy-, bakery-, egg products). Critical evaluation of bioactive-food matrix interactions and determining the extent of synergies between the 3 bioactives are key elements of PATHWAY. PATHWAY will determine the impact of BEF on physiologically-relevant MS (a risk factor for many diseases) endpoints and deliver a better understanding of the role and mechanisms of action of the 3 bioactives and BEF. Parallel in vitro/in vivo studies will enable selection of robust biomarkers by advanced omics techniques. Deliverables will include BEF and generic protocols, best practices and guidelines for planning dietary interventions, and guidance to SMEs for producing health-promoting BEF and for submitting convincing health claim dossiers to EFSA; the latter will be greatly facilitated by one SME partner who has submitted 3 successful dossiers. PATHWAY guidelines will be generic and will apply to a wide range of bioactives and BEF. Impact will be optimised across Europe by targeted dissemination to industry (especially SME), consumer and S&T stakeholders. Young people will be trained in a stimulating interdisciplinary, trans-sectoral environment.";7915110,32;5999231;FP7-KBBE-2012-6-singlestage;/CP-TP;ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA;IT;"MAX RUBNER INSTITUT BUNDESFORSCHUNGSINSTITUT FUR ERNAHRUNG UND LEBENSMITTEL;INTERNATIONAL FOOD NETWORK;INTERNATIONAL LIFE SCIENCES INSTITUTE EUROPEAN BRANCH AISBL;Teknologian tutkimuskeskus VTT Oy;ABRO BIOTEC SL;LEBENSMITTELVERSUCHANSTALT;Campden BRI Magyarorszag Nonprofit Korlatolt Felelossegu Tarsasag;THE LEEDS TEACHING HOSPITALS NATIONAL HEALTH SERVICE TRUST;DEUTSCHES KREBSFORSCHUNGSZENTRUM HEIDELBERG;APPLICATIONS SANTE DES LIPIDES SARL;UNIVERSITY OF LEEDS;GIOTTO BIOTECH SRL;EGE UNIVERSITY;SYDDANSK UNIVERSITET;KAROLINSKA INSTITUTET;NGB GENETICS;SWEDISH OAT FIBER AB;DESARROLLOS PANADEROS LEVANTINOS SLL;CENTRE DE RECHERCHE EN NUTRITION HUMAINE D'AUVERGNE;ADEXGO IPARI, KERESKEDELMI ES SZOLGALTATO KFT;INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE;ADWARE RESEARCH FEJLESZTO ES TANACSADO KFT;AINIA;TEKNOLOGIAN TUTKIMUSKESKUS VTT;JRC -JOINT RESEARCH CENTRE- EUROPEAN COMMISSION";"DE;UK;BE;FI;ES;AT;HU;FR;IT;TR;DK;SE";/SCI;1;0;0;2;0;0 104154;291784;ZIF-MARIE-CURIE;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-COFUND;FP7;Zukunftskolleg Incoming Fellowship Programme;2012-05-15;2018-05-14;https://www.uni-konstanz.de/zukunftskolleg/;"The Zukunftskolleg is an Institute of Advanced Study at the University of Konstanz, which offers postdoctoral researchers a creative space for pursuing frontier research, gaining academic independence and launching their careers at the finest research institutions in Germany and the ERA. For the continuation of the Zukunftskolleg from 2012 onwards, the fellowship format will be opened up to a larger transnational dimension. For this reason, the previous fellowship scheme ends and will be substituted by two new types of incoming fellowships: • 5-year fellowships = ZIF-MC research fellowships • 2-year fellowships = ZIF-MC postdoctoral fellowships Since these two fellowship schemes are significantly different from the previous fellowship scheme, which has ended with the last call for proposals in May 2010, the ZIF-Marie-Curie programme can be considered a completely new scheme. In addition, the Zukunftskolleg will offer 5-year fellowships that are not funded through COFUND. The main objectives of the programme are (1) to attract top-level experienced researchers from outside Germany and develop mutually-beneficial long-term research cooperations; (2) to support the career development of young postdoctoral researchers from across the world by offering a creative environment for innovative research; (3) to foster dialogue and cooperation across disciplines and generations of researchers by creating a productive and supportive community among the fellows; (4) to prepare young academics to continue their careers with the best possible curriculum and research experience; and (5) to reinforce equal opportunities for all researchers. To achieve these objectives, the Zukunftskolleg offers 48 2-year postdoctoral fellowships and 26 5-year research fellowships to excellent postdoctoral scholars who are selected on the basis of their academic track record, the quality and topicality of their research project outline, and their personal aptitude and interdisciplinary interest. During their stay at the Zukunftskolleg, they will gain academic independence and develop the disciplinary, interdisciplinary and professional skills needed to become leading experts in the international research community and decisively shape the research of the future. Thus, the Zukunftskolleg will train researchers who will advance their research fields and take up principal positions in academia and society. Fellowship-years that exceed the timeframe of the COFUND programme will be financed from the university’s own budget.";15605856,6;6242342,64;FP7-PEOPLE-2011-COFUND;/MC-COFUND;UNIVERSITAT KONSTANZ;DE;;;/SCI;1;0;0;2;0;0 95244;254009;FUNSURF;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IEF;FP7;Functional Supramolecular Networks on Surfaces;2010-09-01;2012-08-31;;FUNSURF is an interdisciplinary research project which lies at a natural meeting point between chemistry, physics, materials science and nanotechnology. The project will enable a bright young scientist with an impressive track record to gain a high level of cross-disciplinary training in diverse new aspects of supramolecular self-assembly and reactivity, scanning probe microscopy, photochemistry and optical spectroscopy. The training-through-research basis of FUNSURF focuses on the design, synthesis and characterisation of functional supramolecular networks on surfaces. Many of the structures produced by supramolecular self-assembly display high levels of spatial order making it an ideal method for producing the next generation of functional nanostructured devices. In addition to producing novel, high impact science this project gives the researcher the opportunity to work in an internationally recognised group at a host organisation which provides excellent postgraduate training in both scientific and complementary professional skills. FUNSURF will produce molecular architectures which can be activated by external stimuli to perform specific functions. These include, switching on or off adsorption sites in a network via optically induced changes in molecular configuration and initiating localised chemical reactions. Alongside this the development of Tip-Enhanced Raman Spectroscopy (TERS) will provide a chemically specific characterisation tool with nanoscale resolution. The researcher’s background makes him perfectly suited to achieving these objectives, while the experience of new research disciplines will allow him to cultivate the broad range of skills key to driving new scientific developments in this area. This combination of training and interdisciplinary experience is essential in assuring the researcher attains an independent position at the forefront of future research efforts.;159100;159100;FP7-PEOPLE-2009-IEF;/MC-IEF;KATHOLIEKE UNIVERSITEIT LEUVEN;BE;;;"/SCI;/EDU;/ITT";1;0;0;2;0;0 102080;290077;ENTICE;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-ITN;FP7;Engineering Tribochemistry and Interfaces with a Focus on the Internal Combustion Engine;2012-02-01;2016-01-31;;"The main aim of the ENTICE proposal is to provide professional development in the multidisciplinary field of ENgineering Tribochemistry and Interfaces for IC Engines, capable to develop the new generation of clean and energy-efficient engines. It aims to train the next generation of researchers to work in diverse teams, to cross disciplinary and sectoral boundaries and apply advanced communication and information technologies to work across many scales of time and space. Detailed project objectives are: 1. To provide scientific and professional development to a highly motivated group of early stage researchers (ESRs) to address a number of key interdisciplinary research issues of great importance to the future of transport industries. 2. To facilitate and support scientific and professional development of two experienced researchers (ERs) to enable them to become the research leaders in two challenging interdisciplinary research areas. 3. To disseminate the knowledge and products developed through scientific research to industry, policy makers and the wider academic community for maximum impact of the research. 4. To initiate a sustainable long-term research, training and educational collaboration between the partners involved. Here we propose the development of a training network that brings together some of the key active research groups in Europe, with a leading international reputation, in complementary areas relevant to the fields of tribochemistry and interface design. A number of leading industrial companies, comprising of SMEs and LEs, will engage in training and facilitate the Transfer of Knowledge (ToK) to and from the industrial partner through research programmes for 12 ESRs and 2 ERs. The training programme proposed comprises two key elements; generic training to cover aspects of training required for future research leaders in academia and industry and on-the-job training which will include specialised project-specific skills and development.";3369190;3369190;FP7-PEOPLE-2011-ITN;/MC-ITN;UNIVERSITY OF LEEDS;UK;"WALLWORK CAMBRIDGE LIMITED;SKF BV;SULZER SOREVI;AC2T RESEARCH GMBH;TOTAL MARKETING SERVICES;ECOLE CENTRALE DE LYON;MERCEDES AMG HIGH PERFORMANCE POWERTRAINS LTD;UNIVERZA V LJUBLJANI";"UK;NL;FR;AT;SI";"/LIF;/SCI";1;0;0;2;0;0 105276;911616;CULTURAL ENCOUNTERS;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IIF;FP7;Cross-cultural Encounters – the Travels of Gender Theory and Practice to China and the Nordic Countries;2015-09-01;2016-08-31;;"This interdisciplinary project is concerned with the cross-cultural translation of knowledge and practices that may or may not take place when different cultures interact, and the resulting production of new knowledge. Taking the travelling routes of gender theory and practice to, and also between, China and the Nordic countries as the empirical object of study, the project will focus on the crucial questions of why and how knowledge travels or fails to travel. The project will explore in which forms and by whom knowledge is sent, received, understood, translated, or even refused. The project then seeks to assess the impact of these travels. The main objective is to develop an interdisciplinary framework in the form of an alternative travelling theory to facilitate an improved understanding of the cross-cultural translation of knowledge and practices. The project is significant for the European Research Area, as well as for governments, civil society and public opinion in light of increased cross-cultural interaction between Europe and Asia.";15000;15000;FP7-PEOPLE-2011-IIF;/MC-IIFR;Shanghai University;CN;;;/SCI;1;0;0;2;0;0 109882;612308;AIROPICO;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IAPP;FP7;Academia-Industry Research and Development Opportunities for Picornaviruses;2014-01-01;2018-04-30;;"Viruses belonging to the large family of Picornaviridae such as enteroviruses, rhinoviruses and parechoviruses represent the most commonly encountered infectious agents in mankind. Several research groups in Europe are active on different aspects of picornavirus research. Nevertheless, prevalence, transmission, and pathogenesis are still largely unknown and no therapy is available for picorna infections. Within the present AIROPico project, the partners now are teaming up to combine the disciplines of pathogenesis, diagnostics and therapy development in order to understand disease and to develop effective antiviral treatments.The present AIROPico project will provide interdisciplinary education and training to university scientists and company researchers, through intersectoral staff exchange and collaboration in the context of a highly innovative research and development project on picornavirus biology, diagnostics and therapy. The general aim of this project is to build up a sustainable, interdisciplinary, integrated academia-industry consortium to explore and unravel mechanisms of human picornavirus pathogenesis and to develop fast diagnostics, novel treatment options and additional therapy strategies. The project partners (all active in the field of picornaviruses from different perspectives) will work closely together on biological characterization of virus types, diagnostics and therapy development. The project will concentrate on combining knowledge, experiences and new research techniques (through secondments, recruitment and training) in a focused and joint collaborative effort, needed to tackle the health problems due to picornaviruses, but also needed to tackle the challenges faced in the development and marketing of new diagnostics and treatments.";2542340,99;2542340,99;FP7-PEOPLE-2013-IAPP;/MC-IAPP;Academisch Medisch Centrum bij de Universiteit van Amsterdam;NL;"ARCDIA INTERNATIONAL OY LTD;AB BCN S.L.;HELSINGIN YLIOPISTO;TIB MOLBIOL SYNTHESELABOR GMBH;TURUN AMMATTIKORKEAKOULU;TURUN AMMATTIKORKEAKOULU OY;KATHOLIEKE UNIVERSITEIT LEUVEN;PROTOBIOS OU;TURUN YLIOPISTO";"FI;ES;DE;BE;EE";/LIF;1;0;0;2;0;0 109285;608407;CYCLON HIT;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-ITN;FP7;NANOCARRIERS FOR THE DELIVERY OF ANTIMICROBIAL AGENTS TO FIGHT RESISTANCE MECHANISMS;2014-03-01;2018-02-28;;"The worldwide spread of antibiotic-resistant microorganisms can be viewed as an ecological consequence of the systematic use of antimicrobial agents. Resistant bacteria prevail in healthcare environments where antibiotic selective pressure is intensive. Novel therapeutic approaches are urgently required to deliver the well-documented existing drugs in an optimized fashion to: i) protect them toward degradation; ii) increase their bioavailability; iii) reduce toxic side effects; iv) increase patient compliance and iv) reduce treatment duration and related costs. In this sense, nanocarriers based on cyclodextrins (CDs) are particularly appealing for the delivery of antibiotics. This approach is of main interest for tuberculosis (TB), infections related to Salmonella Typhimurium, Staphyloccocus aureus and for species most frequently implicated in hospital infections such as enteric gram-negative rods. We will design and characterize CD-based nanocarriers, test their ability to encapsulate drugs, study their efficacy in vitro on bacteria and infected cells. The best formulation will be tested in vivo and scaled up. The objectives of the CycloN Hit project are to take full advantage of nanotechnology and of the high level interdisciplinary expertise of the partners to efficiently encapsulate and protect antibiotics in nanocarriers to combat resistant bacteria, and study the mechanisms in biological systems using state-of-the art techniques. This will be accomplished through a strong and demanding training program for 11 Early Stage and 5 young Experienced Researchers which will gather interdisciplinary expertise of 11 Full partners and 6 Associated partners, of which 7 are SMEs. Using the most recent advances in the nanomedicine field, the final goal of the CycloN Hit project is to bring to the preclinical studies an antibiotic formulation for the treatment of TB and more tailored alternative therapeutic approaches for other resistant microorganisms.";3894894,02;3894894,02;FP7-PEOPLE-2013-ITN;/MC-ITN;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FR;"CYCLOLAB CIKLODEXTRIN KUTATO-FEJLES;UNIVERSITA DEGLI STUDI DI CATANIA;NANOLOGICA AB;HELLENIC PASTEUR INSTITUTE;CONSIGLIO NAZIONALE DELLE RICERCHE;""NATIONAL CENTER FOR SCIENTIFIC RESEARCH """"DEMOKRITOS"""""";UNIVERSIDAD DE ALMERIA;UNIVERSIDAD DE CASTILLA - LA MANCHA;GOETEBORGS UNIVERSITET;HASKOLI ISLANDS";"HU;IT;SE;EL;ES;IS";/LIF;1;0;0;2;0;0 102436;303716;MICROBES-2-MODEL;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-CIG;FP7;Marine microbial interactions – physiology, genomics and ecological modeling;2012-03-01;2016-02-29;;"Interactions between marine microorganisms such as symbiosis, competition, and allelopathy determine the structure and function of microbial communities, yet are relatively unstudied. We must understand these interactions at multiple levels in order to predict how marine microbial communities will evolve in a changing world. Here, I propose to study interactions between Prochlorococcus, the most abundant photosynthetic organism in the oceans, and heterotrophic marine bacteria, utilizing a cross-scale approach combining physiology, chemical ecology, functional genomics and ecological modeling. We will: 1) Determine the general mechanism of interaction and the physiological response of two Prochlorococcus and five heterotrophic strains to liquid batch co-culture; 2) Elucidate genes and pathways responding to and mediating these interactions through comparative transcriptomic experiments; 3) Formulate, constrain and test mathematical models of these co-cultures, utilizing the physiological and genomic observations to explore the complexity needed to mathematically represent microbial interactions. The proposed interdisciplinary study will, for the first time, link multiple mechanisms of interaction between marine microorganisms to the genes and pathways involved. The experimentally-informed and tested mathematical models will provide a critical stepping stone towards explicitly representing microbial interactions in global biogeochemical models. Our results will be of special interest given the dominance of Prochlorococcus as a primary producer in the open ocean, and may shed light on the paradox of how microbial interactions can occur in such a diffuse environment. This interdisciplinary study will promote my integration into the EU research community and facilitate ongoing and future collaborations with EU and American scientists studying microbial communities and their dynamics in the changing oceans.";100000;100000;FP7-PEOPLE-2011-CIG;/MC-CIG;UNIVERSITY OF HAIFA;IL;;;/SCI;1;0;0;2;0;0 89965;230802;NANOBIOSENS;ONG;FP7-PEOPLE;FP7-PEOPLE-IRSES-2008;FP7;NANOSENSORS BASED ON NANOMATERIALS;2009-01-01;2011-12-31;;The primary objective of this proposal is to bring together an international and interdisciplinary group of research teams who have different expertise areas to share the knowledge of different elements for building nano-biosensors. The development of future devices requires controlled assembly and placement of individual and/or multiple nano building blocks into the desired locations. By the accomplishment of this research proposal, the advantages of integration of nanomaterials into the structure of biosensors will be feasible. It is expected that the nanomaterial assembled biosensor structures will show an enhanced sensitivity due to the high surface area, higher porosity, and adjusted surface energy. In this research proposal, there are six participants from six countries with different expertise areas in the field of chemical engineering, biomedical engineering, materials science, physics, chemistry, and biology. Different pieces of work will thus be constructed into each other to first of all study their “separate” roles in that assembled piece of work. The international and interdisciplinary group of research team who came together is composed of Turkey, France, Ukraine, Canada, United States and (Rep. of) Korea. The estimated time of the project is 36 months. The proposed programme consists of three stages. STAGE 1 consists of shortly “synthesis of nanomaterials and their controlled assembly and organization of Si wafer substrates”. STAGE 2 is composed of the “biofunctionalization” of these materials built in STAGE 1 and the building a biosensor out of the assembled materials. STAGE 3 will focus on the “field tests” to see how affective these biosensors are working. Six trainings, three general meetings and three workshops are being planned for this research proposal in order to share all the knowledge and information gained throughout the work and to form the basis of long lasting collaborations.;;333000;FP7-PEOPLE-IRSES-2008;/MC-IRSES;MIDDLE EAST TECHNICAL UNIVERSITY;TR;;;/EDU;1;0;0;2;0;0 109149;607996;ALErT;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-ITN;FP7;Anatolian pLateau climatE and Tectonic hazards;2013-10-01;2017-09-30;;"ALErT: Anatolian pLateau climatE and Tectonic hazards, is a virtual campus of 10 European academic and 5 industry partners in the fields of applied Earth sciences, natural hazard monitoring, and knowledge transfer. Our research focus is on the tectonic and climatic boundary conditions along the densely populated margins of the Central Anatolian Plateau, Turkey and associated natural hazards. Due to the international scale of the challenges associated with Global Change and active tectonics in plateau-margin environments worldwide, students with international experience and an interdisciplinary background will be best poised to take future leadership roles in academic, industry or policy realms. We combine the resources and training structures of universities, extramural research departments, and industry partners to equip the next generation of geoscientists with the skill sets they need to meet the challenges of dealing with natural hazards in rapidly changing environments and societies. Our efforts are rooted in (1) research-based learning using a fully interdisciplinary, network-wide approach; (2) state-of-the-art field-based method training and courses on data analysis; (3) interoperability of instructors and students; (4) secondments in industry; and (5) teaching communication skills, ultimately needed for knowledge transfer to industry, administration, and the public.";3338802,52;3338802,52;FP7-PEOPLE-2013-ITN;/MC-ITN;UNIVERSITAET POTSDAM;DE;"BSF SWISSPHOTO GMBH;DOKUZ EYLUL UNIVERSITESI;ORACLE Deutschland B.V. & Co. KG;UNIVERSITY OF PLYMOUTH;ISTANBUL TEKNIK UNIVERSITESI;UNIVERSITA DEGLI STUDI ROMA TRE;INSTITUT DE PHYSIQUE DU GLOBE DE PARIS;UNIVERZITA KOMENSKEHO V BRATISLAVE";"DE;TR;UK;IT;FR;SK";/LIF;1;0;0;2;0;0 109883;612415;PROAIR;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IAPP;FP7;Active PROtection of multi-material assemblies for AIRcrafts;2014-01-01;2017-12-31;;"'The proposal is devoted to development of the novel active corrosion protection systems for multi-material combinations used in the aircraft design. The development of such new approaches is only possible via deep mechanistic investigation of the degradation processes in confined environments formed at multi-material joints. The second essential stage is finding the synergistic inhibiting combinations which can provide effective suppression of corrosion processes in the case of galvanically coupled dissimilar materials. The ultimate step is introduction of inhibiting compounds to the protective layers, adhesives and sealants used in multi-material design of aircrafts. The proposal also aims in creation of stimulating and interdisciplinary R&D and training partnership, with actors from the academia and private sector, promoting the exchange of ideas, methods, techniques as well as enabling an accelerated technology transfer from science to industrial scale and of course a continuous collaborations between the stakeholders. The topic demands strongly innovation and interdisciplinary skills, since there is a lot of pressure from the private sector to develop more sustainable solutions for light-weight design of “green aircrafts”. The developed protection solutions must be compliant with environmental regulations, must present reduced thickness/weight, and must promote energy saves, with longer lifetime. Moreover it has to be considered that the related processing and assembly steps have to be economically competitive. Thus, the actual times are very challenging for this field and new skills and trained people are an acknowledged need.'";891711,43;891711,43;FP7-PEOPLE-2013-IAPP;/MC-IAPP;HELMHOLTZ-ZENTRUM GEESTHACHT ZENTRUM FUR MATERIAL- UND KUSTENFORSCHUNG GMBH;DE;"AIRBUS DEFENCE AND SPACE GMBH;UNIVERSIDADE DE AVEIRO;TEHNOLABOR OU";"DE;PT;EE";/LIF;1;0;0;2;0;0 92148;235199;WOPINS;ONG;FP7-PEOPLE;FP7-PEOPLE-IEF-2008;FP7;Walking Old Paths in New Shoes: Individual Trajectories to Retirement and the Welfare State in Austria and Germany;2010-09-01;2012-08-31;;"This project carries out a comparative investigation of retirement behaviour in Austria and Germany. Drawing on the theoretical concept of ‘pathways to retirement’ (Kohli & Rein 1991) it examines individual trajectories leading to labour market exit both through policy-analysis as well as empirically. The project proposes an interdisciplinary analytical approach and mix of methods. The empirical bases are process-produced work history data spanning over 30 years (linked employer-employee data). A novel sequence-based statistical technique is used to identify empirical typologies of common ‘pathways to retirement’, subsequently used as input in explanatory models of retirement behaviour. The scientific objective is to contribute to our knowledge about the determinants of different retirement behaviours, taking account of a wide, interdisciplinary array of mechanisms through which people allocate to different ‘pathways to retirement’. The project is tailored as to allow the postdoctoral research fellow to reach well-defined objectives in terms of skill acquisition and career advancement. It will allow her to obtain the practical skills necessary for the use of administrative data in applied labour market research and to further advance her skills in econometric evaluation research. Both of these skills have become crucial assets for labour market researchers in public and private institutions.";;156043,51;FP7-PEOPLE-IEF-2008;/MC-IEF;EUROPEAN UNIVERSITY INSTITUTE;IT;;;"/SCI;/EMP";1;0;0;2;0;0 102785;295181;INTERBONE;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IRSES;FP7;The interplay among bone cells, matrices and systems;2012-04-01;2015-06-30;;It is now clear that there are multiple regulatory pathways that orchestrate the interplay between the skeleton and other organs to maintain the correct homeostasis of the body. INTERBONE is an interdisciplinary network for international exchange of scientists which will study the central role of the skeleton in three areas of health. INTERBONE will coordinate research and training activities between 5 institutions in Italy, Netherlands, Brazil, India and USA each with highly complementary and distinctive expertise. Work on energy metabolism will build on previous research findings that suggest a link between bone derived signals, glucose metabolism and insulin sensitivity. The network will also investigate the role of candidate secreted factors in the disruption of hematopoiesis in the development of leukemia. These activities will utilize new conditional knockout mouse models. Research on fracture repair and tissue regeneration will address biomaterials interactions with cells, and stimulation of angiogenesis in fracture repair with biophysical approaches. The planned research collaboration is supported by a programme of staff exchanges, training and networking activities. The network will involve regular meetings integrated with established international conferences in bone-related research, which will support networking and dissemination, a workshop on tissue regeneration and angiogenesis, and a programme of webinars. The staff to be exchanged will comprise 13 ESRs and 7 ERs who will benefit greatly from the transfer of knowledge and international experience. INTERBONE also makes a contribution to the opening of the European Research Area to international cooperation, and interaction with three of Europe’s strategic global partners in this emerging interdisciplinary area of research.;254100;233100;FP7-PEOPLE-2011-IRSES;/MC-IRSES;UNIVERSITA DEGLI STUDI DELL'AQUILA;IT;ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM;NL;/SCI;1;0;0;2;0;0 187941;625508;ESNETNARR;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IEF;FP7;Networks and Narratives: The Transnational Community of European Studies 1957-2004;2014-09-01;2016-08-31;;"Challenges to elite accounts of European integration are central to the current EU crisis. It is therefore vital to understand how European elites construct these ‘narratives’. The proposed research will examine the transnational community of European Studies (ES) since 1957, as it had a crucial role in shaping these narratives. It will ask how the position of scholars within this network affected what they said or implied about the spatial reach and extent of integration. The project will integrate multilingual discourse analysis of narratives in canonical scholarly texts about enlargement, spatial differentiation and culture, with social network analysis (SNA) of this scholarly community’s transnational organisation. This SNA will use institutional, citation, CV and interview data. To de-centre Anglophone scholarship, and to examine the effects of transnational integration and relations between prestigious core locations (Germany and France) and less developed scholarly sites, the project will focus on the disciplines of political science, sociology and contemporary history in three case studies. These are the EC/EU accessions of the UK (1957-73), Spain (1975-86) and Poland (1990-2004). The applicant proposes an ambitious, original contribution to research on integration. He will publish several high-quality works, extend his transnational network of contacts and acquire crucial skills in postgraduate teaching, PhD supervision, management and research. New SNA and research interviewing skills will be vital for his innovative interdisciplinary combination of qualitative and quantitative methods. He will be based at Portsmouth University’s Centre for European and International Studies Research, which has excellent training facilities for early career researchers. He will work with Professor Wolfram Kaiser, a leading contemporary historian and interdisciplinary ES scholar with a research background in transnational networks, narratives and other relevant areas.";309235,2;309235,2;FP7-PEOPLE-2013-IEF;/MC-IEF;UNIVERSITY OF PORTSMOUTH HIGHER EDUCATION CORPORATION;UK;;;;1;0;0;2;0;0 109978;323343;DIRTPOL;ONG;FP7-IDEAS-ERC;ERC-AG-SH5;FP7;The Cultural Politics of Dirt in Africa, 1880 - present;2013-09-01;2018-08-31;;Dirt permeates everyday life in urban Africa, but it is more than an empirical substance: dirt is also an idea—or a complex set of representations—that shapes local perceptions of sexuality and the body, and influences people’s attitudes towards waste, recycling, urbanisation, ethnicity and migration. Dirt is a vital category for understanding urban cultures in Africa, and it has a history that has yet to be examined in detail. Besides the work of epidemiologists and occasional anthropological accounts, however, there have been no sustained studies of locally situated understandings of dirt in Africa. This project will identify and reflect on African representations and understandings of dirt in a comparative historical perspective for the first time. With reference to four key themes—colonialism, the environment, sexuality and ethnicity—everyday cultural practices will be addressed in Nairobi (Kenya) and Lagos (Nigeria). In examining particular African locations and historical contexts, the project will evaluate not only the social and political histories of specific ‘dirty’ discourses, but also the theoretical and methodological directions that the concept of dirt generates as a starting point for comparative interdisciplinary case-studies. Employing a range of methodologies, the two teams of researchers at the Participating Institutions (Kenyatta University, Nairobi, and University of Lagos) in Years 1-5, and the doctoral and postdoctoral researchers at the Host Institution (University of Sussex) in Years 3-5, will identify local African representations and understandings of dirt. In addition to other major outputs, the PI will build a website that addresses political, methodological, theoretical and ethical issues, as well as providing an archive of primary resources. Key objectives include: to learn from positive and negative valuations of words connoting dirt in Africa, and to develop a paradigm for interdisciplinary work in African cultural studies.;2209800;2209800;ERC-2012-ADG_20120411;/ERC-AG;THE UNIVERSITY OF SUSSEX;UK;"KENYATTA UNIVERSITY;UNIVERSITY OF LAGOS-UNILAG";"KE;NG";/SOC;1;0;0;2;0;0 109272;606728;MOLESCO;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-ITN;FP7;"""MOLECULAR-SCALE ELECTRONICS: Concepts, Contacts and Stability """"MOLESCO""""""";2014-01-01;2017-12-31;;"'The MOLESCO network will create a unique training and research environment to develop a pool of young researchers capable of achieving breakthroughs aimed at realising the immense potential of molecular electronics. In part this will involve the major challenges of design and fabrication of molecular-scale devices. To deliver this step-change in capability, MOLESCO will coordinate the activities of internationally-leading scientists from six different countries. MOLESCO has secured the participation of nine private sector partners, including one of Europe’s leading industrial electronics-research laboratories (IBM Research–Zurich) as a full partner. A highly-integrated approach to the experimental and theoretical aspects of molecular-scale electronics will deliver the fundamental knowledge and new fabrication strategies needed to underpin future nanotechnologies targeted for electronics applications. MOLESCO represents a highly interdisciplinary and intersectoral collaboration between teams with an extensive portfolio of skills, including molecular synthesis, fabrication of molecular junctions, imaging of molecular junctions with atomic resolution, measurements of charge transport, and electronic structure and transport calculations. Training will be delivered in a series of high-priority actions primarily aimed at providing the researchers with an outstanding career development platform. The network has a strong focus on interdisciplinary training; it is built on several well-established and fruitful collaborations between the partners and seeks to bridge an existing educational gap in the European Research Arena. The development of complementary skills (presentation, management, technology transfer, IP protection, outreach and intersectoral training) will be implemented throughout the lifetime of the project. Specialist professional training in dissemination and outreach will be delivered by our Associate Partner BLP, a professional media production company.'";3985376;3985376;FP7-PEOPLE-2013-ITN;/MC-ITN;UNIVERSITY OF DURHAM;UK;"UNIVERSITAET REGENSBURG;FRIEDRICH-ALEXANDER-UNIVERSITAET ERLANGEN NUERNBERG;UNIVERSITAT BASEL;IBM RESEARCH GMBH;UNIVERSITAET BERN;SYDDANSK UNIVERSITET;LANCASTER UNIVERSITY;FUNDACION IMDEA NANOCIENCIA;TECHNISCHE UNIVERSITEIT DELFT";"DE;CH;DK;UK;ES;NL";/LIF;1;0;0;2;0;0 88937;229460;RATIONALISM;ONG;FP7-IDEAS-ERC;ERC-AG-SH5;FP7;Rediscovering Theological Rationalism in the Medieval World of Islam;2008-12-01;2013-11-30;;The project is frontier research in several respects. It aims at crossing the boundaries between 3 main disciplines of academia, viz. Islamic and Jewish Studies and Studies of Eastern Christianity. The followers of the 3 denominations constituted a unique cultural commonality in the medieval world of Islam. They shared Arabic as their common language and often read the same books, so that a continuous exchange of ideas, texts, and forms of discourse was the norm. This widely accepted historical reality notwithstanding, scholars usually opt for a one-dimensional approach with a focus on either Muslim, Jewish or Christian authors. The project aims at radically breaking away from this pattern replacing it with a multi-dimensional interdisciplinarity that is justified by the historical reality of the periods and regions under investigation. Yet it goes beyond mere interdisciplinarity in that the applicant seeks to connect between the leading researchers in the field who are also separated by political boundaries. Close cooperation will be sought with researchers from the West and the Islamic world and an attempt will be made to bring them together during the two int nal workshops scheduled for Years 2 and 4. The primary purpose in bringing scholars from such diverse disciplines and worlds together is to create a new quality within research. As such, the project also serves a wider political purpose: In a world in which borders increasingly gain significance, the project is meant to demonstrate that intellectual history characteristically disregard any such borders and that intellectual symbiosis was often the norm rather than the exception, and that this holds particularly true in one of today s hottest conflict areas, the Middle East.;1864760;1864760;ERC-2008-AdG;/ERC-AG;FREIE UNIVERSITAET BERLIN;DE;;;/SOC;1;0;0;2;0;0 90197;230267;ALREG;ONG;FP7-IDEAS-ERC;ERC-AG-SH2;FP7;Analysing Learning in Regulatory Governance;2009-09-01;2013-09-30;;This four-year interdisciplinary project addresses the question what has been learned through the use of better regulation ? Better regulation is a flagship policy on the Lisbon agenda for growth and jobs. Its aims are to provide new governance architectures for law-making, to increase the competitiveness of the regulatory environment, and to secure wide social legitimacy for multi-level systems of rules. Whilst most of the research has looked at how better regulation is changing, this project will produce findings on what has changed because of better regulation. Theoretically, the project will use (and significantly improve on) theories of policy learning. Empirically, it will cover Denmark, Italy, the Netherlands, Poland, the UK and the EU including multi-level analysis and analysis by sector of regulation. Methodologically, the project will draw on comparative analysis of types of learning, experiments with regulatory policy-makers in six countries and the European Commission, large-n analysis of impact assessments, backward-mapping of legislation (to appraise the role played by better regulation in the formulation or laws in the UK and the EU), meta-analysis of case-studies and co-production of knowledge with better regulation officers. Dissemination will target both stakeholders (i.e., policy officers, civil society organizations, and business federations) and academic conferences in political science, law, and risk analysis, with a major research monograph to be completed in year 4 and a final interdisciplinary conference.;948448;948448;ERC-2008-AdG;/ERC-AG;THE UNIVERSITY OF EXETER;UK;;;/SOC;1;0;0;2;0;0 105265;316866;SOMATAI;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-ITN;FP7;Soft Matter at Aqueous Interfaces;2012-10-01;2016-09-30;;Soft nanotechnology is generally considered as a field that will have a major impact on technological developments in near future. However, the fundamental understanding of the wealth of new structures lacks far behind, despite supporting activity from material science. Such an understanding is indispensable for sustainable growth of this important research domain and its applications. A physics-oriented interdisciplinary education is urgently needed to guide young researchers to the point where they can tackle the relevant fundamental questions. SOMATAI is set up to provide just such training by combining two distinct scientific fields: Soft matter science is a well established interdisciplinary field for the bulk investigation of polymers, colloids, and liquid crystals with response amplitude and time to external stimuli as a function of soft matter structure being of special interest. The second highly relevant field is interface science, since nano-structured materials contain a huge area of internal interfaces which have an essential impact on material properties. The application of the soft matter approach to interfaces promises new and deeper understanding of interfacial phenomena. Interfaces of a water phase to a solid, liquid or gaseous second phase are of special interest and a focal point of SOMATAI. Such interfaces are highly relevant to products from European industry (food, cosmetics, paints) and processes (washing, coating, water purification). They have an outstanding importance from a scientific point of view due to specific interactions at such interfaces. This carefully planned teaching and research programme in a network of 10 leading academic partners, 1 large scale companies, 2 SMEs, and 4 top-level associated partners from Germany, Taiwan and the USA will ensure that young researchers are given an excellent training in a pioneering research domain of high scientific and technological relevance, where Europe can take a leading position.;3562776,87;3562776,87;FP7-PEOPLE-2012-ITN;/MC-ITN;FORSCHUNGSZENTRUM JULICH GMBH;DE;"GERMAN UNIVERSITY IN CAIRO;NIZO FOOD RESEARCH BV;MAX PLANCK INSTITUT FUR EISENFORSCHUNG GMBH;COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES;FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS;DSM Innovation Center B.V.;EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH;UNIVERSITEIT UTRECHT;TECHNISCHE UNIVERSITEIT EINDHOVEN;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;KATHOLIEKE UNIVERSITEIT LEUVEN;LEIBNIZ-INSTITUT FUR POLYMERFORSCHUNG DRESDEN EV;LS INSTRUMENTS AG";"EG;NL;DE;FR;EL;CH;BE";/LIF;1;0;0;2;0;0 101576;284544;PARM-2;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IAPP;FP7;"VIBRO-IMPACT MACHINES BASED ON PARAMETRIC RESONANCE: Concepts, mathematical modelling, experimental verification and implementation";2012-01-01;2015-12-31;http://fp7.imaps.aber.ac.uk/parm2.html;"The aim of the project is to enhance the potential and output of vibrating machines and decrease their ecological footprint by implementation of parametric resonance (PR). Compared with the regular resonance, the PR is characterized by a much higher intensity within a wide range of frequencies. The advantage of a PR-based machine was demonstrated with a prototype PR screener (PRS) developed and produced by the project partners. The PRS demonstrated large amplitudes of high-frequency lateral oscillations and self-vibro-insulation and could process a naturally wet fine granular material. However, the PR is instable, and its use as an effective operating mode assumes, among others, creation of a ‘stabilized instability’ regime. This is an inspiring and challenging high-tech task for combined efforts of applied mathematicians and engineers. The extraordinary PR features together with open nontrivial theoretical and engineering problems provide a motivation to undertake this interdisciplinary research. The main objectives are: to develop a technically sound control of PR amplitude; to develop mathematical models for the process of material separation with a PRS; to design PRS-related screens with given stiffness and minimal bending stresses, and to design other types of PR-based separators and crushers. The enhancement of vibro-cutting/drilling tools via the development of the underpinning theory and application of the PR principle will also be an objective. An exchange of fundamentals and technical concepts between the large-scale research and the micro/nano PR studies is assumed. The project activities will be based on close cooperation and targeted secondments between academia and industry. As a result, a large number of ESRs will have a unique opportunity to be trained through research, working on all interdisciplinary aspects, starting from the conceptual design and modelling and finishing with prototypes/demonstrators of new PR-based machines and tools.";1775354;1775354;FP7-PEOPLE-2011-IAPP;/MC-IAPP;ABERYSTWYTH UNIVERSITY;UK;"MINING COMPANY LOGINOV AND PARTNERS;POLITECHNIKA RZESZOWSKA IM IGNACEGO LUKASIEWICZA PRZ;ISOTOP LTD;TEL AVIV UNIVERSITY;LOUGHBOROUGH UNIVERSITY;THE UNIVERSITY OF LIVERPOOL;Eurotech Sp. z o.o.";"UA;PL;IL;UK";/IND;1;0;0;2;0;0 92531;236642;VRSURGICALSIMULATION;ONG;FP7-PEOPLE;FP7-PEOPLE-IEF-2008;FP7;VR Surgical Simulation for training: simulator design, optimisation and assessment;2009-09-07;2010-09-06;;"The better surgeons are trained, the safer surgery procedures will be. Virtual reality (VR) surgical simulators offer new possibilities for surgeon learning, training and assessment, but they are complex to design, requiring contributions from different disciplines, such as engineering, medicine and psychology. Unfortunately, it is difficult to achieve a proper interdisciplinary communication. Most projects in surgical simulation are strongly influenced by the engineering point of view, with weak contributions from the rest. This unbalance and the lack of industry support often lead to a premature end of the project. The fellowship aim at the Imperial Robotics and Imaging Research Group, in the Faculty of Medicine, is to evolve to a professional maturity and to reach a multidisciplinary view to improve the way simulators are applied to minimally invasive surgery (MIS). The training objectives are focused on enhancing my research skills and strengthening my interdisciplinary knowledge by acquiring medical complementary skills. This will allow to apply my previous background on computer science, VR and simulation techniques (see the commercial insightARTHROVR® simulator) to satisfy surgeons’ needs. The main research objectives are: 1. To develop education and training programs for surgeons based on learning theory, using the potential of virtual reality resources. 2. To research which algorithms and simulation techniques need to be improved in order to make surgical simulators a more valid tool; and to design VR surgical simulators adapted to the surgeons’ needs. 3. To perform surgical simulator assessment and to research on the evaluation of surgical competencies. A Personal Review and Development Plan in conjunction with Dr. F. Bello and the Staff Development Unit at the Imperial will be compiled. They will mentor me, supervising the attainment of the fellowship aims for relevant contribution to European excellence and competitiveness.";;87067,84;FP7-PEOPLE-IEF-2008;/MC-IEF;IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE;UK;;;"/SCI;/EMP";1;0;0;2;0;0 95725;253316;X-RAY PUMP-PROBE;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IOF;FP7;X-ray pump-probe spectroscopies - new tools to study ultrafast surface dynamics -;2010-04-01;2012-03-31;;Recent progress in laser science allows the creation of femto- to attosecond X-ray light pulses and paves the way for a completely new generation of experiments investigating ultrafast processes in biology, chemistry and physics. Intensive research efforts worldwide are pursuing the implementation of “pilot” experiments that demonstrate the scientific potential of this area. However, the challenging nature of femtosecond X-ray sources requires experts with interdisciplinary training in X-ray laser-science and in the research areas that can benefit from its use. The goal of the proposed project is to develop and establish X-ray pump-probe spectroscopies using high-harmonic light sources to study femtosecond surface dynamics. Three ultrafast surface science areas will be addressed: surface magnetism, chemical reactions and phase transitions. The proposed interdisciplinary experiments will yield new insight in femtosecond quasiparticle interactions and will also impact possible applications in magnetic memory production, catalysis and organic materials. The applicant is an expert in surface science, who will complement his skills in organic materials, femtochemistry and high-harmonic X-ray generation with the Kapteyn-Murnane Group at JILA (USA), who are leading scientists in the field. The proposed project is at the cutting edge of ultrafast surface science and will promote EU research in this field during the return phase with Prof. Aeschlimann (GER) at the University of Kaiserslautern, who is one of the global key opinion leaders for ultrafast phenomena. The proposed project will help the fellow researcher gain professional maturity and to actively participate in shaping the next generation of ultrafast research with X-ray pulses, an area that is rapidly expanding with increasing worldwide availability of high harmonic and free electron laser light sources.;159381,8;159381,8;FP7-PEOPLE-2009-IOF;/MC-IOF;TECHNISCHE UNIVERSITAET KAISERSLAUTERN;DE;;;"/LIF;/EDU";1;0;0;2;0;0 93306;239171;DUS;ONG;FP7-PEOPLE;FP7-PEOPLE-IRG-2008;FP7;Dissent and Urban Spaces;2009-10-01;2014-04-02;;"What makes citizens choose a particular form of protest and how does space function as mediator between these citizens and their political acts? These questions address the international social contentions of this century. This research offers an interdisciplinary analysis of urban spaces and protests, with a focus on the late 20th and early 21st centuries. The research’s goal is to enrich the discourse about the relationships between dissent and public space. Addressing these relationships, this research offers a window into how people use, manipulate, claim, and appropriate urban space while advocating for their own values. Thus far, we have no coherent theory explaining the relationship between space and contentious politics. We do have significant empirical and theoretical accounts of how prevailing forms of popular struggle vary and change from one political regime to another, but there is little written about the spatial physicality of these struggles. This research seeks to further understand the phenomena of dissent. It contributes to this goal by setting the rather abstract notions of citizenship and democracy into a concrete framework of time, place and meaning. The research aims are: 1.Building an analytical, interdisciplinary framework for the spatial physicality of dissent. 2.Advancing a comparative display of forms of citizenship and cultural identities. 3.Offering significant new perspectives on how different and changing notions and practices of citizenship relate to issues in our multicultural society. The project is based on empirical analysis in 10 cities, with the aide of translators and research assistances.";100000;100000;FP7-PEOPLE-IRG-2008;/MC-IRG;TEL AVIV UNIVERSITY;IL;;;"/SCI;/EMP;/COO";1;0;0;2;0;0 92977;237955;FACETS-ITN;ONG;FP7-PEOPLE;FP7-PEOPLE-ITN-2008;FP7;Fast Analog Computing with Emergent Transient States - Initial Training Network (FACETS-ITN);2009-09-01;2013-08-31;;FACETS-ITN is a research and training network involving partners from 11 universities and research centres, 3 industrial companies and 1 semi-industrial research centre from 6 European countries. It combines competencies in neurobiology, computational neuroscience, information science, physics and electrical engineering. The scientific goal is to experimentally and theoretically explore the structure and the computational principles of biological neural circuits using in-vitro and in-vivo neurobiological experiments as well as analytical approaches, model building and simulation techniques. The concepts of learning and plasticity will be of particular importance. Based on the input from biology and modelling it is expected to prepare the grounds for novel hardware based computing devices that make use of such principles. Such devices will be built and operated in the form of large scale demonstrators as part of the research plan. Within the training network 21 selected Ph.D. students will be integrated into an existing international research environment and receive a strongly interdisciplinary training. The training comprises an intense exchange and visiting programme, specific training workshops for all scientific areas covered as well as in non-scientific key competencies.. This training concept will enhance their original academic education in order to cope with the challenges of this diverse international research environment. The proposed training programme will be closely coupled to existing research projects as well as graduate programmes of participating universities. It will create a sustained infrastructure based on web-based learning as well as on scientific interdisciplinary networks and the intersectional exchange with industry. The community building among Ph.D. students from different disciplines will include students from other projects, in particular the current FACETS integrated project and its planned successor.;4677779;4677779;FP7-PEOPLE-ITN-2008;/MC-ITN;RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG;DE;"INSTITUT NATIONAL DE RECHERCHE ENINFORMATIQUE ET AUTOMATIQUE;TECHNISCHE UNIVERSITAET GRAZ;KUNGLIGA TEKNISKA HOEGSKOLAN;FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.;IDT EUROPE GMBH;DEBRECENI EGYETEM;ALBERT-LUDWIGS-UNIVERSITAET FREIBURG;Silicann Technologies GmbH;ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE;Honda Research Institute Europe GmbH;INSTITUT POLYTECHNIQUE DE BORDEAUX;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;TECHNISCHE UNIVERSITAET DRESDEN";"FR;AT;SE;DE;HU;CH";"/SCI;/EDU";1;0;0;2;0;0 91265;227138;BRIGHTANIMAL;ONG;FP7-KBBE;KBBE-2008-1-2-02;FP7;Multidisciplinary Approach to Practical and Acceptable Precision Livestock Farming for SMEs in Europe and world-wide;2009-05-01;2011-04-30;;BrightAnimal will contribute to economically, socially and environmentally sustainable development by outlining a practical and acceptable methodology for precision livestock farming. To achieve this goal, BrightAnimal has the following mission: To produce a framework for European and non-European small and medium enterprises on effective and acceptable precision livestock farming and to create an international, interdisciplinary network for further development and dissemination. The main activity and achievement of BrightAnimal will be the elaboration of a book on effective Precision Livestock Farming in Europe and world-wide with special consideration of small and medium enterprises. The book aims at describing current and near-future techniques in PLF, especially taking into account both the practicality for SMEs as well as their acceptability (in the broader sense). The book will also try to set the scene for future developments. As the second component of the framework, BrightAnimal will produce best precision livestock farming practices (BPLFP) in a series of “problematic” areas such as aquaculture, beef, sheep and chicken. These best practice guides will be released to the public domain in the form of booklets. A third deliverable of the project will be a practical showcase activity showing the Good Practices in action in the European Centre of Excellence of Automatic Identification and Data Capture in the UK. BrightAnimal will organise interdisciplinary conferences for opinion exchange and cross-disciplinary discussions. It is of great importance to include opinions from outside Europe. We have been pleased to accept partners from the following ICPC countries: Thailand, Malaysia, South Africa, Brazil and China and from Australia as a third country. Other non-funded partners from third countries will also join the project.;1146362,39;997425;FP7-KBBE-2008-2B;/CSA-CA;FOODREG TECHNOLOGY SL;ES;"KASETSART UNIVERSITY;SMART IDENTIFICATION LIMITED;NOFIMA AS;MINISTRY OF AGRICULTURE AND AGRO-BASED INDUSTRY;CONSUMER GOODS COUNCIL OF SOUTH AFRICA;EESTI MAAULIKOOL;DEPARTMENT OF PRIMARY INDUSTRIES AND RESOURCES SOUTH AUSTRALIA;DANMARKS TEKNISKE UNIVERSITET;AIDC UK LTD;BITLAND ENTERPRISE APS;Institute of Quality standards & Testing Technology for Agro-products, CHINESE ACADEMY OF AGRICULTURAL SCIENCES;EMPRESA BRASILEIRA DE PESQUISA AGROPECUARIA EMBRAPA;AALBORG UNIVERSITET";"TH;UK;NO;MY;ZA;EE;AU;DK;CN;BR";/VAS;1;0;0;2;0;0 98955;273072;ECOSTPOLITIK;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-IEF;FP7;"""Explaining EU's External Relations. Origins and consolidation of EU's policy towards Eastern Europe and Russia, 1969-1985""";2011-04-04;2013-04-03;;'The research project deals with the European Community’s (EC) relations with Eastern Europe in the period 1970-1985. It explores the attempts of the EC and its member states to shape, implement, and further develop an autonomous and collective Eastern policy (Ostpolitik) as part of a more general effort at asserting a distinct political role for the EC in the international arena. Focusing on the multilateral and pan-European level, and taking into consideration the broader international context, the project will offer a historical analysis of the development of the EU’s Common Foreign and Security Policy in general, and of the determinants of EU’s enlargement towards Eastern Europe and EU policy towards Russia in particular. The project will contribute to improve our knowledge of the Cold War, of the integration process, and of Europe as a continent. It also aims at appealing to scholars of law, European politics, and International Relations, in the conviction that knowledge of the past serves a better understanding of the present and helps scholars and decision-makers respond to current challenges. The ECOSTPOLITIK is a truly interdisciplinary project. First, it will merge different historical sub-disciplines, i.e. Cold War, European integration, economic history. Second, it will discuss interpretations and theories developed by jurists dealing with the matter. Third, it will make use of theories and concepts of political and social sciences as heuristic tools to appreciate more comprehensively both the EU polity and international negotiations. I will base my research on secondary literature, memoirs, archival sources (documents), and contemporary journals, periodicals and media sources. As I conceive of this project as a truly interdisciplinary research, I will also make targeted use of law and political science literature on matters such as the use of economic means in international relations, governance, decision-making, and external relations of the EC.';193349,6;193349,6;FP7-PEOPLE-2010-IEF;/MC-IEF;LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE;UK;;;"/EMP;/EDU;/NET";1;0;0;2;0;0 98605;274035;ACOLA;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-IIF;FP7;Analysis of controllability and control landscapes for quantum systems;2011-06-12;2013-06-11;;"The proposed research program is in the field of quantum control. This is a vibrant, actively-growing and highly interdisciplinary branch of science of broad interest to the physics and chemistry communities, with many researchers involved in Europe, the US and worldwide. The project addresses two fundamental topics in quantum control. The first is controllability of Markovian and non-Markovian open quantum systems (i. e., systems interacting with the environment). While controllability properties of Markovian systems have been studied, controllability of non-Markovian systems and of Markovian systems with controls addressing both the system and its local environment remain largely unexplored. The second topic is the analysis of control landscapes for both closed and open quantum systems. The quantum control landscape is defined as the objective as a function of the control field (e.g., a shaped laser pulse). The landscape structure, particularly the existence of traps, determines the difficulty of finding the optimal solutions to the underlying control problem and is therefore of great practical significance. Preliminary results of the researcher A. Pechen and the host D. Tannor show that, in contrast to recent claims in the literature, traps may exist in the dynamical landscape. The project is interdisciplinary and will apply analytical and numerical tools to quantum control problems that are at the forefront of research in physics and chemistry. The project will be performed in the research group of Prof. Tannor at the Weizmann Institute of Science. It will contribute significantly to European excellence and competition in the field of quantum control through transferring knowledge and research expertise of Dr. A. Pechen (Princeton University) from the US to Europe. The major project goals are to advance the field of quantum control as well as to establish a mutually beneficial cooperation between the US and European researchers.";184362,4;184362,4;FP7-PEOPLE-2010-IIF;/MC-IIF;WEIZMANN INSTITUTE OF SCIENCE;IL;;;"/SOC;/COO";1;0;0;2;0;0 88863;231010;EUKNOW;ONG;FP7-PEOPLE;FP7-PEOPLE-ERG-2008;FP7;European Universities in the area of Knowledge. Collaboration and networks in teaching and research;2009-01-01;2013-12-30;;"The overall fellowship objectives are twofold: • First to consolidate the outcomes of the EIF research project through: - the organisation of workshops in which results will be disseminated and future collaboration possibilities will be discussed. Organised at the University of Sheffield, where the fellow has been offered a permanent appointment as lecturer in Higher Education and Lifelong Learning, these workshops will involve a number of participants in the EIF EUROTAC project, researchers in the field, representatives from policy bodies operating in the higher education (HE) policy sector and colleagues from the EIF host institution (i.e. University of Oxford). It is hoped that the workshop will be instrumental in providing fieldwork sites for the two projects to initiate during the three-year fellowship; • Second to build on the EUROTAC project which mainly focused on the topic of Joint Masters programmes as a collaborative response to the Bologna Process and other convergence agendas in Europe by: a- using part of the ERG grant as seed-corn funding to initiate a research project on interdisciplinary collaboration, with a particular focus on international capacity building initiatives in interdisciplinary fields involving the social sciences; b- exploring the feasibility of a comparative and longitudinal project on inter-institutional academic and research collaboration in Europe and prepare research proposals for substantial funding (i.e. ERC Starting Independent Researcher Grants).";45000;45000;FP7-PEOPLE-ERG-2008;/MC-ERG;THE UNIVERSITY OF SHEFFIELD;UK;;;"/SCI;/SOC";1;0;0;2;0;0 91927;237673;RETHINK LEARNING;ONG;FP7-PEOPLE;FP7-PEOPLE-IOF-2008;FP7;An Alternative Model of Learning: Implications of Learning Sciences Research for the Creation of Effective Technology-Enhanced Learning Environments;2009-08-01;2013-05-31;;"The European Commission stresses the importance of innovation, research, high-quality education and lifelong learning as Europe develops as a knowledge-based society and economy. In order to enhance the scientific knowledge on innovative pedagogies and accelerate new forms of learning and teaching, more interdisciplinary learning sciences research is required, to inspire a faster and more progressive change with regard to Europe’s education and training systems. Consequently, the overall goal of this research project is to gain a refined knowledge on how students come to understand and how faculty can support learning with understanding, creating effective technology-enhanced learning environments. The objectives tackled are as follows: (1) In order to refine the scientific knowledge on how students come to understand, cognition will be studied in its physical, social and cultural context, conducting an interdisciplinary literature review and outlining a sensitizing framework; (2) Explorative case study research on how expert instructors in the field of education design effective technology-enhanced learning environments that engage students in deep learning will be conducted. In this respect, three selected courses at Harvard Graduate School of Education will be investigated to inform the theory-building process of the study; (3) Characteristics of effective technology-enhanced learning environments will be derived from learning sciences research (see 1 and 2) to guide the development of a new learning model. In addition, a questionnaire will be designed to survey the outlined characteristics of the developed model against a broader audience of students at Harvard Graduate School of Education and further develop and enhance the generalizability of the theory. (4) Implications for curriculum development as well as learning and teaching in higher education will be drawn from the American context to transfer and implement the insights gained to the European context.";238095,57;238095,57;FP7-PEOPLE-IOF-2008;/MC-IOF;UNIVERSITAET ST. GALLEN;CH;;;"/COO;/EDU";1;0;0;2;0;0 87947;215118;BRAVISSIMO;ONG;FP7-PEOPLE;PEOPLE-2007-1-1-ITN;FP7;BRAssinosteroid Venture Increasing StudentS' International MObility;2008-09-01;2012-08-31;;A future challenge for the European agriculture is to satisfy the growing demands for food in a sustainable manner. Understanding the basic mechanics of plant growth will ultimately lead to our ability to increase yield, while decreasing the need for fertilizer and pesticides. Plant growth is regulated by developmental programmes that can be modified by environmental cues acting through endogenous signalling molecules such as plant hormones. Brassinosteroids (BRs) are the growth-promoting polyhydroxylated steroid hormones of plants. BRs are implicated in multiple developmental processes and as such they determine important agronomic traits including biomass, crop yield, and stress and pathogen adaptation. In addition to the well-elucidated BR biosynthetic pathway, during the past decade a significant progress led to the identification of multiple BR signalling components. Despite this key issues remained unsolved. It is still unclear how BRs control growth, how the levels of BRs change throughout development and in response to environment and how different hormonal pathways interact within cells. It is still unknown if different signaling pathways mediated other non BRs effects and how the redundancy in BR signaling components fine tunes the pleiotropic action of those hormones. The BRAVISSIMO network will created a training programme which will guarantee the comprehensive education needed in future to establish a competitive and leading European science in the interdisciplinary field of plant signaling. BRAVISSIMO will strengthen the BR field of research in Europe and will increase its ability to compete effectively with non-EU researchers via coordination, integration and introduction of more interdisciplinary approaches.;1950000;1950000;FP7-PEOPLE-2007-1-1-ITN;/MC-ITN;VIB;BE;"CROPDESIGN NV;UNIVERSITE DE LAUSANNE;IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE;MAGYAR TUDOMANYOS AKADEMIA SZEGEDIBIOLOGIAI KUTATOKOZPONT;CENTRE DE RECERCA EN AGRIGENOMICA CSIC-IRTA-UAB-UB;WAGENINGEN UNIVERSITY;EBERHARD KARLS UNIVERSITAET TUEBINGEN";"BE;CH;UK;HU;ES;NL;DE";"/EMP;/SOC;/EDU";1;0;0;2;0;0 103505;297925;N-LINK;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IEF;FP7;"""Normannitas: Landscape, Identity and Norman Kingdoms.""";2012-05-07;2014-05-06;;"'The main aim of N-LINK is to compare England and Italy before and after the Norman Conquest, exploring specific European case studies of historic landscape evolution. The research questions are whether, how and why the Normans changed the settlement patterns within their Kingdoms, specifying similarities and differences between both countries by applying and developing new interdisciplinary landscape-focussed methods and tools (especially GIS and HLC). I will investigate the role of the Normans in shaping and exploiting two border lands in their Kingdoms of England and Sicily (in the former kingdom of Northumbria, northern England, and the medieval Principality of Capua, Italy, both border lands which were controlled by Norman conquerors). The hypothesis I seek to investigate in my research proposal is whether a specific Norman Identity (‘Normannitas’) was expressed in the ‘building’ of conquered landscapes. Thus, I have chosen to compare two Norman territories, scientifically selected, analysing the effects of the conquest on both landscapes, using a multidisciplinary and interdisciplinary approach integrating archive research and archaeological data through GIS. Research objectives are: to analyse: geomorphologic conditions and previous use of natural resources; pre-existing settlement organization and land exploitation; results from archaeological excavations and surveys; to identify Norman settlements and features, reconstructing their networks and defining Norman development phases in medieval settlements; to test and apply GIS-based HLC in this analysis. This is the first time that the same project has ever expressly aimed to tie together British and Italian landscapes, sharing methodologies and historiographical issues in order to develop a new method of research. Therefore, N-LINK has to bridge two different European academic approaches, building new links across ‘cultural European borders’.'";200371,8;200371,8;FP7-PEOPLE-2011-IEF;/MC-IEF;UNIVERSITY OF NEWCASTLE UPON TYNE;UK;;;/SCI;1;0;0;2;0;0 90414;229750;IMPACTG;ONG;FP7-REGPOT;REGPOT-2008-1-01;FP7;Improvement of the research competitiveness in neuroscience at the Ernst Moritz Arndt University of Greifswald;2009-05-01;2012-04-30;;"Neuroscience is the fastest growing area in basic scientific research. Neuroscience is an interdisciplinary field designed to improve our understanding of neural communication mechanisms in health and disease. Treatments, cures, and, above all, knowledge are the possibilities that continue to be discovered through neuroscientific research. The Neuroscience Group at the Medical Faculty of the University of Greifswald promotes interdisciplinary investigations from the level of gene expression in single neurons to imaging of localized regions of the human brain and neurorehabilitation. The Neuroscience Group at the Ernst-Moritz-Arndt University is located in a convergence region, and the paucity of high-tech, expensive equipment for research, the lack of a critical mass of experienced researchers, a reduced level of experience and knowledge of researchers as well as fewer international collaborations with highly competitive groups put severe limitations on the impact of our publications and our capacity to attract research funds from EU programs. Therefore the major aim of this proposal is to redress this balance by (i) stimulating the realization of the full research potential of our Neuroscience Group by acquisition of cutting-edge technology and equipment; (ii) increasing the quality and international impact of our research by cooperation with high profile institutions and recruitment of experienced researchers; (iii) improving S&T experience and knowledge of researchers by short term and long term trainings with our Strategic Partners and exchange of know-how and experience with the scientific experts; (iv) organization of workshops to facilitate knowledge transfer at international level; (v) plenary meetings; (vi) dissemination and promotional activities. These measures should allow the Neuroscience Group in Greifswald to successfully participate and contribute to the EU Framework Program projects.";1339185,2;1042530;FP7-REGPOT-2008-1;/CSA-SA;UNIVERSITAET GREIFSWALD;DE;;;/SCI;1;0;0;2;0;0 88459;214699;AUDIS;ONG;FP7-PEOPLE;PEOPLE-2007-1-1-ITN;FP7;Digital Signal Processing in Audiology;2008-10-01;2012-09-30;;The rapid advance in embedded digital signal processing technology has recently led to significantly enhanced hearing devices. Besides the very basic task of restoring loudness, modern hearing aids and cochlear implants feature a range of advanced processing capabilities such as beamforming microphone arrays, noise reduction and automatic controls. While some of these features have already resulted in improved performance, advanced approaches to signal enhancement, to auditory scene analysis and to signal reproduction strategies promise much improved user benefits. The application of advanced signal processing schemes in hearing instruments for the improved rehabilitation of hearing impaired users, however, requires close collaboration of researchers in digital signal processing, audiology and psychoacoustics. The ITN AUDIS will perform research and training in digital signal processing for applications in hearing instruments. The unique approach lies in the research and development of advanced statistical signal processing algorithms in the interdisciplinary area of audiology. This network thus reacts to the strong demand of hearing aid and cochlear implant companies for highly qualified researchers who are proficient in both the advanced signal processing methodologies and their application in the context of hearing instruments, and who are thoroughly familiar with user requirements in this domain. This network consists of 4 university and 2 industrial partners and associated partners. A key characteristic of this network is that all partners have substantial experience in interdisciplinary work and can thus provide exciting research opportunities to network fellows.;2953467;2953467;FP7-PEOPLE-2007-1-1-ITN;/MC-ITN;RUHR-UNIVERSITAET BOCHUM;DE;"KUNGLIGA TEKNISKA HOEGSKOLAN;SIEMENS AUDIOLOGISCHE TECHNIK GMBH;UNIVERSITY OF SOUTHAMPTON;COCHLEAR EUROPE LIMITED;KATHOLIEKE UNIVERSITEIT LEUVEN";"SE;DE;UK;BE";"/EMP;/SOC;/EDU";1;0;0;2;0;0 92914;245751;PROFICIENCY;ONG;FP7-REGPOT;REGPOT-2009-1;FP7;Strengthen IUNG’s proficiency on “Managing the Production of Food and feedstuff, their safety and quality under global Climatic Change”;2009-12-01;2014-05-31;;"The Institute of Soil Science and Plant Cultivation (IUNG) is a brilliant Polish Research Institute. ProFiCiency aims at strengthening IUNG’s excellence, through technological, human and partnership capacities fostering, and most of all through a complete reshaping of its internal organisation. IUNG ambitions to adopt a totally integrated interdisciplinary approach around four interdisciplinary priority research areas (Soil Quality; Land Use; Production Systems and Techniques; and Plant Products Quality and Safety) to converge towards excellence on a crucial topic: “Managing the Production of Food and feedstuff, their safety and quality under global Climatic Change”. This ambition is the red line of the whole Action Plan, derived from the SWOT analysis. Measurables objectives are the acquisition of 17 pieces of equipment; the reorganisation of laboratories, a new HR policy, the hiring of 5 experienced researchers, intense mobility trainings (56 outgoing, 30 incoming), a sustainable agriculture platform, 2 international conferences, 8 workshops, 3 trainings, 1 open day and 2 farmers days, 1 website, 8 newsletters. The ProFiCienCy project will rely on 16 partners all across the EU. It has raised wide support reactions from official bodies (Polish Ministry of Agriculture, Agricultural Chamber of Lublin, Foundation for Polish Science, Regional Agrochemical Stations, Association of Tobacco Growers, National Council of Individual Farmers Union “Solidarity”). The main expected project outcomes are a better penetration within the ERA and IUNG’s recognition as the most promising research centre in Poland on the interaction between climate changes and the production of food and feedstuff of quality and high safety. ProFiCienCy also corresponds to a complementary funding of IUNG from cohesion funds and the FP7, since IUNG benefited from €3M funding from the European Regional Development Fund.";3133504,67;2800000;FP7-REGPOT-2009-1;/CSA-SA;INSTYTUT UPRAWY NAWOZENIA I GLEBOZNAWSTWA, PANSTWOWY INSTYTUT BADAWCZY;PL;;;"/REG;/LEG";1;0;0;2;0;0 188196;627593;NEXSUS;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IEF;FP7;Network-based Expert-Stakeholder Framework for Sustainable Remediation;2014-10-10;2016-02-08;;The management of contaminated land has moved through different stages over the last few decades, each stage being characterized by a specific approach. The most recent stage is that of sustainable remediation, whereby decisions on the management of contaminated sites have to be sustainable across all the three pillars of sustainable development (environmental, economic and social). In particular, ensuring the social acceptability and support of remediation strategies and actions is currently regarded as being of high importance. The proposed research project aims to improve the development and assessment of sustainability in contaminated land management processes, through the development of an interdisciplinary framework for the integration of new social sustainability indicators with existing indicators of environmental and economic sustainability applicable to remediation projects. The development of this framework requires first the integration of expert and stakeholder-based assessments of social sustainability and the subsequent integration of the social assessments with environmental and economic indicators of sustainability. To achieve these ends, the project advances an original interdisciplinary approach that draws on social network analysis (from sociology), project ecologies (from economic geography) and multi-criteria decision analysis and sustainable remediation (from environmental science). The expected results are relevant for researchers interested in sustainable remediation, to policy makers, experts and consultants involved in contaminated site management as well as for site owners, local authorities, site neighbors and the interested public.;124621,4;124621,4;FP7-PEOPLE-2013-IEF;/MC-IEF;UNIVERSITA CA' FOSCARI VENEZIA;IT;;;;1;0;0;2;0;0 188153;628982;TEACH-IN;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IEF;FP7;Teacher leadership for school improvement: community capacity building towards effective leadership, educational success and social cohesion;2014-04-22;2016-04-21;;The applicant, Dr. Gisela Redondo Sama is associate professor at the Department of Sociological Theory, Philosophy of Law and Methodology of the Social Sciences at the University of Barcelona since 2009. She is also researcher at CREA (Centre for Research in Theories and Practices that Overcome Inequalities). She earned her PhD in Sociology in 2011 and she is an expert in democratic education and school improvement. The host organisation is the Faculty of Education at the University of Cambridge, UK, with Dr. David Frost supervising the activities of the fellow. The main aim of the fellowship is to help the applicant advance on her career in education and social sciences research, under the guidance of world renowned experts. The research will focus on developing a comprehensive understanding of teacher leadership and its effectiveness for school improvement and how to implement it in schools and communities in successful ways. The interdisciplinary analysis across teacher leadership, successful actions and learning communities can provide an innovative and powerful framework to combat early school leaving and promote social cohesion. It will also provide the applicant with research training related to the methodology and concepts of education in the particular area to be developed, as well as in complementary skills like project management and academic leadership, thus enabling her to manage interdisciplinary research in the future. The 24 months of fellowship will provide the fellow with the opportunity to gain knowledge and skills which will contribute to the development of her career. The results of the research that she will conduct will mean a relevant impact for educational policies at national and EU-level.;299558,4;299558,4;FP7-PEOPLE-2013-IEF;/MC-IEF;THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;UK;;;;1;0;0;2;0;0 188173;629517;EXTREMISM;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IEF;FP7;Interactive extremism. A comparative psychosocial study of the emotional dynamics of far 'right' extremisms in Germany and Great Britain;2015-06-01;2016-05-31;;"This project will focus on an international comparison of the interaction of extremist groups with the general public, an area where very little research has been done despite the ambitious European targets related to the intervention of and prevention of extremism. Due to the rise of Islamist and right-wing extremism in European countries, interventions are needed urgently. The primary objective is to analyse the psychosocial underpinnings of extremism in relation to the societies of Great Britain and Germany as a precondition to develop better means to deal with threats to democracy in the EU. We propose the psychosocial concept of 'interactive extremism' to grasp the relationship between the extremist groups and the population in Great Britain and in Germany, especially in the emotional public sphere. This notion of interactive extremism will firstly be applied to explore the interactions between the right-wing- extremist groups and the violent jihadist movement. Secondly, it will be applied to the interactions between the right-wing-extremist groups and the so-called centre of society. In a first phase, media analysis will be applied in the field of offline and online communications of right-wing-extremist and Islamist groups. In a second phase, we will conduct 16 focus groups in Germany and in GB. To analyse the data, we will follow a psychosocial and interdisciplinary approach in order to grasp the interaction of societal and psychological processes, including emotional and unconscious processes. This will result in mapping the psychosocial conditions under which escalation and de-escalation of extremisms are most likely to occur in order to develop counterstrategies to address extremism. We will follow a psychosocial approach in order to grasp the interaction of societal and psychological processes, including emotional and unconscious processes. Our approach is interdisciplinary, as it combines theories and methods of the disciplines of psychology, especially psychoanalysis, sociology, media studies and political science. With our new approach additional insights as follows will be gained: •Understanding of the extremist interactions between extremist groups and between extremist groups and the general public •Understanding of the internationalization of extremism";110803,2;110803,2;FP7-PEOPLE-2013-IEF;/MC-IEF;BOURNEMOUTH UNIVERSITY;UK;;;;1;0;0;2;0;0 188161;629256;RHAK;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IEF;FP7;Networks of Trade and Religion in Richard Hakluyt's 'Principal Navigations';2014-08-04;2016-08-03;;This proposal will enhance the career development of the IEF through a research project that engages with Richard Hakluyt’s 'Principal Navigations' the most important collection of early modern English travel writing. The project will introduce a more sophisticated understanding of religious identity into the discussion of Hakluyt and his sources. In light of recent research on religious identity formation, we can no longer label Hakluyt as simply a staunch Protestant when he featured material from those of other faiths and his anti-Catholic rhetoric simply reflected state policy. The second objective is to re-establish the centrality of global trade to Hakluyt’s vision. Scholars have devoted disproportionate attention to the material relating to the Americas despite the fact that it comprises just one third of the Principal Navigations. The majority of the text is devoted to trading ventures. These overlooked voyages to Russia, Turkey and Persia will form the heart of this project. The project will be interdisciplinary in engaging with aspects of early modern trade, religion, culture and literature. It will also be interdisciplinary in blending methodologies of textual analysis with prosopography and social network theory. Outputs will be a monograph alongside open access digital resources in the form of a prosopographical database and collection of biographies. Research will be disseminated also through conference organization and participation. An outreach programme in schools will help to create lasting dialogue between the university and local community, whilst helping students become proficient in the use of digital resources and creating a future generation of researchers equipped with transferable skills. It will enable the IEF to enhance their contribution to the European knowledge economy and help them to attain a senior academic position within the EU.;191359,8;191359,8;FP7-PEOPLE-2013-IEF;/MC-IEF;NATIONAL UNIVERSITY OF IRELAND GALWAY;IE;;;;1;0;0;2;0;0 187983;626055;HAVIX;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IEF;FP7;Harmonic Analysis for optimal coding and the design principles of brain's Visual corteX;2014-04-01;2016-03-31;;"HAViX is an interdisciplinary project on the interplay between frame theory, nonlinear approximation and group theory, aimed to obtain results relevant to the understanding of the functional architecture of brain's visual cortex and to applications to artificial vision. The objectives are highly relevant mathematical results with respect to deep current problems in harmonic analysis, and concern the characterization of noncommutative shift-invariant systems, the study of geometric properties of continuous wavelet transforms and the introduction of new techniques in nonlinear approximation. New approaches will be developed to address such topics, involving techniques from different areas of mathematical analysis such as abstract harmonic analysis and noncommutative Fourier duality, complex analysis, geometric and nonlinear analysis on groups. The expected results will permit to severely improve the present models of the functional architecture of the visual cortex and provide solid instruments for geometric data encoding and compression. The proposed mobility is from France, research center CAMS, mixed unit CNRS - EHESS, to Spain, Autonoma University of Madrid, Mathematics Department, and is motivated by the complementarity of competencies between the applicant, D. Barbieri, whose research activity in Italy and France allowed him to develop a strong interdisciplinary experience on different techniques of Analysis on Groups and on Modeling of the Visual Cortex, and the Scientist in Charge, E. Hernandez, who has an extremely high research expertise in Wavelet Theory, Nonlinear Approximation and Function Spaces, and belongs to a Host Institution that is a world excellence in Harmonic Analysis.";166336,2;166336,2;FP7-PEOPLE-2013-IEF;/MC-IEF;UNIVERSIDAD AUTONOMA DE MADRID;ES;;;;1;0;0;2;0;0 187848;624428;JERICHO;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IEF;FP7;Understanding and Preserving Early Islamic Jericho: Towards a Management Plan for the Site of Khirbet el-Mafjar (Palestine);2014-08-01;2016-07-31;;"Khirbet al-Mafjar is the most outstanding and best preserved Umayyad palace in the Near East and represents the first steps in the development of early Islamic architecture. It was built by the Umayyad Caliphs in their pursuit of a new visual culture and a theatre for their protocol apparatus, reinforcing their political identity, while establishing an instrument for territorial control in the making of the newly established Caliphate. It stands nowadays as an essential component of the Palestinian identity, and a basic landmark of their Cultural Heritage. The main objective of the project is to conduct interdisciplinary research on this complex, assessing its present condition and reviewing previous research, in order to draft a Management Plan which will guarantee its preservation and public enjoyment. The project involves researching how Cultural Heritage can become an engine of socio-economic development, a tool to reinforce the cultural identity of the local population and in the establishment of intercommunity dialogue that might help in the resolution of the current conflict.The fragmentary character of previous research was due mainly to approaches applied, as well as to political vicissitudes related to its location. This proposal intends to make an important step forward by building up an analytical strategy based on the methodological principles of Archaeology of Architecture, using the monument as a document, a stratified repository of material and social information about its transformation and change of use, gathering all sources of information into interdisciplinary interpretative models. This integration of archaeological, technological and historical research of the built heritage with its preservation and management provides the chance of finding in the material culture sources of historical and technological information which offer simultaneously the choice to understand its History and to provide technical knowledge required for its preservation.";308587,8;308587,8;FP7-PEOPLE-2013-IEF;/MC-IEF;KOBENHAVNS UNIVERSITET;DK;;;;1;0;0;2;0;0 185568;614960;PALEOPLANT;ONG;FP7-IDEAS-ERC;ERC-CG-2013-SH6;FP7;Palaeolithic Plant Use in the Western Mediterranean;2014-07-01;2015-12-31;;This project deals with one of the big gaps of knowledge in prehistory, how plant foods and resources were used by preagrarian societies. Plants have been fundamental for human societies across the planet. However, it is a blank when it comes to archaeological evidence of humans eating and exploiting them during most part of Prehistory. This work aims at changing the meat/hunting centred paradigm of Palaeolithic subsistence by readdressing human plant exploitation through a novel interdisciplinary approach. The main objectives are: 1) To assess wild plant exploitation among Palaeolithic-Epipalaeolithic societies, 2) To appraise resilience and change in Palaeolithic-Epipalaeolithic plant use, and 3) To improve archaeological methodology and fieldwork. The chronology of analysis –from the Late Middle Palaeolithic to the Epipalaeolithic- includes two extremely interesting periods: a) the transition from the middle to the upper Palaeolithic with neanderthal extinction and early presence of modern humans which gives us the opportunity to explore and compare whether these groups exploit plant resources in a different way, and b) the climatic change from the Late Pleistocene to the early Holocene which allows to evaluate how last hunter-gatherers from the region adapt to climatic change and new ecological conditions. The challenge of the work is to obtain archaeological visibility of plant use through and interdisciplinary approach that combines: pollen analysis, the study of plant macroremains including underground storage organs (USOs), micromorphology, analysis of microremains such as phytoliths and starch, ethnobotany and use-wear analyses on tools. The different types of evidence to be analysed come from relevant archaeological sites from Spain, Portugal and Morocco. Because a project at this scale has not been developed before, major scientific developments and impact in archaeological science can be safely expected.;384345;384345;ERC-2013-CoG;/ERC-CG;UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA;ES;;;"/SCI;/SOC";1;0;0;2;0;0 103356;299998;CulturalGeosemantics;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IEF;FP7;Geosemantics for Cultural Heritage Documentation – Domain specific ontological modelling and implementation of a Cultural Geosemantic Information System based on ISO specifications;2012-09-01;2015-01-28;;"The goal of this project is the integration of semantic Cultural Heritage applications with professional Geoinformation. Based on recent developments in both disciplines it will now be possible to create the conceptual basis and to implement systems that have the advantages of the two worlds and are in their combination more powerfull than just the simply addition of the two. The result will be a Cultural Geosemantic Information System, based on ISO standards for both disciplines. The implementation of this new approach will provide institutions and scientific projects of this domain with a methodology and a tool to present the history of cultural digital objects in their geographic context with state of the art geoinformation technologies. State of the art semantic tools will be available to perform spatial queries and integrate the data in the Linked Open Data Cloud to become part of the Semantic Web. Results can be applied to portals like ‘Europeana’, the European initiative with the goal to make Europe's cultural and scientific heritage accessible to the public or to Research Infrastructures for interdisciplinary reseach in the humanities, just to name two. The domain of Cultural Heritage Ducumentation is extremly interdisciplinary and therefore a system like this will bridge the gaps between various discipline specific conceptualisations. Methodological and conceptual base for the project is the ISO certified ontology of the CIDOC CRM (Conceptual Reference Model) for Cultural Heritage Documentation which was developped at the Institute of Computer Science of the Foundation of Research and Technology-Hellas (FORTH-ICS). For Geographic Information exists the extensive ISO 19100 Series as standard. The implementation research will be executed at the FORTH-ICS laboratory with its unique semantic infrastructure for Cultural Informatics. Part of it was just realized last year in the course of the EU funded 3D-COFORM project related to 3D collection formation.";167847,6;167847,6;FP7-PEOPLE-2011-IEF;/MC-IEF;FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS;EL;;;/SCI;1;0;0;2;0;0 109386;612546;ENRICH;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IRSES;FP7;ENRICH: EC-ChiNa Research Network on Integrated Container Supply CHains;2013-10-01;2017-09-30;;The overall aim of this proposed exchange programme “ENRICH” is to bring together an international team of researchers to establish a research network, with a wide variety of skills in operations research, safety and security studies, green logistics, economic modelling, ICT, and intermodal management to develop a container supply chain (CSC) integration methodology, aimed at addressing long-lasting changes in operational, environmental, economic, technical and managerial practices in different segments of the rail, road, air and sea transport industries from an overall supply chain perspective. The network is a physical and virtual grouping of academics and researchers designed to create an interdisciplinary think-tank and knowledge exchange platform for enhancing CSC resilience and sustainability in today’s and tomorrow's operational environments, in which a high level of uncertainty exists due to economic crisis, security risks, climate change, and every changing technologies. The proposal is for a project of eight partners (5 EU members, 1 AC member and 2 Third Country members) with extensive exchange of both experienced researchers (ERs) and early stage researchers (ESRs) during four years to fully explore the complementary strengths and synergies within the consortium. This project will support and reinforce the collaborations amongst the participants and help establish a long-term research co-operation. The research will increase the European research capacity in this vital and rapidly developing container transportation field, and also maintain and enhance the EU’s leading position in the areas of supply chain resilience and sustainability. Moreover, the interdisciplinary nature of the proposed exchange programme offers a link for research and training of the involved ERs and ESRs in a collaborative academic environment.;592200;592200;FP7-PEOPLE-2013-IRSES;/MC-IRSES;LIVERPOOL JOHN MOORES UNIVERSITY;UK;"UNIVERSITEIT ANTWERPEN;HOGSKOLEN I MOLDE;EDINBURGH NAPIER UNIVERSITY;THE UNIVERSITY OF LIVERPOOL;GOETEBORGS UNIVERSITET";"BE;NO;UK;SE";/LIF;1;0;0;2;0;0 108045;328605;Quantum control;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IEF;FP7;"Tailoring decoherence for controlling spin systems: Deepening foundations; expanding applications";2013-05-01;2015-04-30;;During the last decades quantum control methods have developed into a central research subject in Physics. Improvements in the understanding of these quantum phenomena are also enabling the use of these effects in a growing number of applications. In particular new control methods have been emerging for extending the life of quantum states and manipulating their targeted transfers, which can influence numerous areas of application ranging from spin-based quantum computers to biological applications. This project is directed to expand this combination of basic principles and applications: starting from hitherto unexplored foundations of quantum control methods for tailoring spin evolutions, I seek to gain a better understanding of these and tailor them to applications in the areas of nuclear magnetic resonance spectroscopy and imaging. These dual goals, involving quantum-mechanical basic developments and spectroscopically-aimed applications for chemistry, biophysics and medicine, will be explored in the ideal interdisciplinary environment that the Weizmann Institute offers for these purposes. Towards this end I have established a series of collaborations with both Prof. L. Frydman, an expert on the development of magnetic resonance principles and technologies, and with Prof. G. Kurizki, an expert on the foundations of quantum control. To further enhance the prospects of this interdisciplinary connection, my Humboldt-supported training in the field of quantum control at Dortmund University in Germany under the supervision of Prof. D. Suter, and at the National University of Cordoba in Argentina under the supervision of magnetic resonance experts Profs. P. Levstein and H. Pastawski, put me in a privileged position to get the maximum out of this experience. I trust that with this research stage, I will be able to fulfill my strategic long-term goal to develop novel Physics-based strategies to control spins, that can find new specific purposes in Chemistry and Biology.;220290,4;220290,4;FP7-PEOPLE-2012-IEF;/MC-IEF;WEIZMANN INSTITUTE OF SCIENCE;IL;;;/SCI;1;0;0;2;0;0 105032;318908;POREEN;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IRSES;FP7;Partnering Opportunities between Europe and China in the Renewable Energies and Environmental industries;2013-01-01;2016-12-31;;"The research project aims at integrating and combining economic, legal and engineering competencies to analyze the level of economic cooperation reached so far between China and Europe in the renewable energy and the environment industries and to identify specific areas to boost partnership opportunities. Using a multi disciplinary approach, the exchanged staff will work on three main research areas. The first one is focused on trade and investment flows and aims at identifying critical issues, gaps, and potentials in Europe-China relationships. Major effects of Europe-China agreements on foreign direct investments (FDI) and trade flows are examined. Problems encountered and opportunities to be seized at firm level will also be analyzed. The economic perspective is supported and enriched by the engineering and legal perspectives. Engineering knowledge is fundamental to defining concretely the sectors, products and processes which have high deployment potential. Engineering research activity is focused on two main research areas, both related with energy efficiency and carbon dioxide reduction: mobility and the transportation sector and low carbon buildings. The legal knowledge is relevant to understanding obstacles due to the regulatory environment, as well as to identifying appropriate solutions to enhance collaboration. Main investigation areas will be: offshore oil and gas and renewable energy; anti-dumping; environmental and social standards and corporate social responsibility. POREEN aims at increasing the availability of interdisciplinary studies, with a comprehensive overview of Europe-China relations. Developing integrated knowledge is fundamental to provide useful and reliable information to support EU and local policymakers, as well as companies working in/with China. POREEN should lay the ground for further related studies on this topic and establish integrated and interdisciplinary research links between European and Chinese centres of excellence.";718200;718200;FP7-PEOPLE-2012-IRSES;/MC-IRSES;UNIVERSITA DEGLI STUDI DI MACERATA;IT;"GLAWCAL LIMITED;ASSOCIAZIONE ISTITUTO UNIVERSITARIODI STUDI EUROPEI;CHAMBRE DE COMMERCE ET D'INDUSTRIE DE TOULOUSE;UNIVERSITA POLITECNICA DELLE MARCHE;UNIVERSITY OF ULSTER";"UK;IT;FR";/SCI;1;0;0;2;0;0 100495;264362;TOPBIO;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-ITN;FP7;Two Photon Absorbers for Biomedical Applications;2010-12-01;2015-03-31;;Two-photon absorption is a photophysical process with diverse applications in medicine (photodynamic therapy), neurophysiology, cell biology (microscopy, photo-activated drugs) and biomedical engineering (fabrication of micro-needle arrays and tissue scaffolds). Many of these applications will only have a major impact when better dyes become available with stronger two-photon absorption, as well as improved secondary properties (photostability, biocompatibility, etc). Advances in optical engineering will also be critical. Two-photon absorption is an important newly emerging supra-discipline at the intersection of Biology, Chemistry, Physics and Engineering. This network will be the first initiative of its kind in this area. TOPBIO will train young researchers in many different aspects of the field, by coupling together research groups with internationally recognized expertise in synthesis, molecular design, theory, photophysics, photobiology, cell biology, engineering, nanotechnology, microscopy and laser physics. We aim not only to train ESR and ER in an interdisciplinary manner but also (by developing new generations of functional dyes and applying them in real biomedical applications) to improve the quality of life in Europe and to strengthen the EU economy. TOPBIO will provide an excellent mechanism for promoting interdisciplinary training, by exchanging PhD students on secondments between collaborating laboratories, through regular progress meetings, workshops and tutorial schools. TOPBIO brings together leading experts from universities and private sector organizations across Europe. It has an exceptional ratio of private to academic partners (1:2). The perfect match of complementary expertise, multidisciplinarity, high involvement of companies and focus on the real needs of society will enable us to deliver high quality training in skills which are perfectly matched to the needs of future employers, thus producing a workforce which will be in high demand.;3232751,34;3232751,34;FP7-PEOPLE-2010-ITN;/MC-ITN;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FR;"AARHUS UNIVERSITET;KEEMILISE JA BIOLOOGILISE FUUSIKA INSTITUUT;FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS;AMPLITUDE SYSTEMES SA;CONSIGLIO NAZIONALE DELLE RICERCHE;POLITECHNIKA WARSZAWSKA;UZDAROJI AKCINE BENDROVE STANDA;CIS BIO INTERNATIONAL SAS;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;LZH LASER ZENTRUM HANNOVER E.V.";"DK;EE;EL;FR;IT;PL;LT;UK;DE";"/EDU;/NET";1;0;0;2;0;0 94711;252369;NEGEOP;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IEF;FP7;"""Neighboring and the Geopolitics of Ethnically """"Mixed Cities""""""";2010-07-12;2012-07-11;;This proposal is an extension of my intellectual development and research experience towards my attempt to establish an interdisciplinary centre for the study of urban politics. My previous work was widely acknowledged and explored in Israel and the US, but so far it has had no visibility in the EU due to lack of resources. Academically, this research proposal aims to fill the empirical and theoretical lacunae in the existing body of knowledge that deal with contested cities in Europe and elsewhere by offering a new interdisciplinary perspective about how people and communities use, appropriate, and claim the everyday space of their neighbourhoods while advocating their own values and rights. Beyond the empirical input of this research, its intention is to contribute to the existing knowledge in urban studies and to the formulation of a theoretical basis concerning the relevance of geopolitics to the study of cities. Additionally, this project intends to add to the growing literature on cities such as Belfast, Berlin, and Brussels by contextualizing the very specific—and perhaps exceptional—case of Israel within the existing experience, academic knowledge, and research on other cities.;174903,2;174903,2;FP7-PEOPLE-2009-IEF;/MC-IEF;THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;UK;;;"/SCI;/EDU;/ITT";1;0;0;2;0;0 103434;294901;PEPTIDE NANOSENSORS;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IRSES;FP7;"Development of Electrochemical Peptide Nanosensors for protein and antibody detection";2012-05-01;2015-04-30;;"The overriding goal of the proposed research program is the development of novel reagentless, electrochemical peptide based sensors for the detection of multiple diagnostic proteins. The approach, which will utilize electrochemistry to monitor the binding-induced folding of peptide/polypeptide used as recognition elements, will be rapid, specific, convenient, and critically, selective enough to be employed directly in blood serum and –we propose- whole blood. This goal will be achieved bringing together an international and interdisciplinary group of research teams and building a collaborative environment for research, innovation and technology transfer in the field of electrochemical nanosensors. This program will allow the exchange of knowledge and expertises through training visiting periods of early stage and experienced researchers. The training will involve each single aspect of sensor development. For this reason, the research teams selected encompass all of the requisite expertises and each of them has a particular focus on a single step of sensor production and testing. The outcome of the fellowship will be crucial for the early stage researchers involved. This in fact will strengthen their scientific knowledge through a focused training at the host institutions and will facilitate the acquisition of experience in new, interdisciplinary fields at the interface of analytical chemistry, electrochemistry, molecular biology and clinical chemistry. The program will also allow the exchange of experienced researchers. This will give the possibility to build a strong net of collaboration, which will be very important for future careers of the involved scientists. The laboratories involved have similar objectives but with completely different scientific approaches and expertise, this program will help the integration and collaboration among the research teams and the establishment of a long-term collaboration between Europe and key Third Countries.";218700;191400;FP7-PEOPLE-2011-IRSES;/MC-IRSES;UNIVERSITA DEGLI STUDI DI ROMA TORVERGATA;IT;"FUNDACIO INSTITUT CATALA DE NANOCIENCIA I NANOTECNOLOGIA;UNIVERSITY OF KENT";"ES;UK";/SCI;1;0;0;2;0;0 96994;264738;ICARENET;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-ITN;FP7;Intelligent Context-Aware Systems for Healthcare, Wellness, and Assisted Living;2011-01-01;2014-12-31;;"Context awareness has the potential to revolutionise the way people interact with information technology. Whereas conventional computers merely interpret explicit user input, context-aware systems analyse and automatically respond upon users’ behaviour and situation he/she is in. This enables electronic systems to assist users in situations in which the use of conventional computers and mobile devices is out of question. A particularly relevant field are healthcare, wellness, and assisted living (HWA) applications, which is at the focus of the proposed network. Research on context awareness has continued to intensify in the last decade due to the availability of cheap sensing technologies and mobile systems. Still, building reliable context-aware systems that can deal with complex real-life situations and environments remains an open research challenge and requires a multi-disciplinary effort. iCareNet will make a decisive contribution towards solutions, leveraged through an interdisciplinary perspective ranging from sensing and sensor integration, to human-computer interaction and social factors involved in the deployment of context-aware applications. Robust and scalable system architectures and design methodologies are the principal objective of all iCareNet efforts. iCareNet unites efforts of an interdisciplinary network of leading European research groups and a strong industrial participation. Researchers will receive comprehensive inter-domain training through a series of network-wide training events on topics including signal processing, behaviour inference techniques, privacy and security, and social aspects. A number of measures including the establishment ERASUMS partnerships, formal recognition of lectures, and the design of long-term joint Ph.D. programs will ensure that the network leads to long-lasting collaborations and benefits for the involved institutions.";4995608;4995608;FP7-PEOPLE-2010-ITN;/MC-ITN;TECHNISCHE UNIVERSITEIT EINDHOVEN;NL;"IT-UNIVERSITETET I KOBENHAVN;IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE;NOLDUS INFORMATION TECHNOLOGY BV;Teknologian tutkimuskeskus VTT Oy;DEUTSCHES FORSCHUNGSZENTRUM FUR KUNSTLICHE INTELLIGENZ GMBH;EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH;LANCASTER UNIVERSITY;PHILIPS ELECTRONICS NEDERLAND B.V.;Future Shape GmbH;EDNA PASHER PHD AND ASSOCIATES MANAGEMENT CONSULTANTS LTD;UNIVERSITAT PASSAU;TEKNOLOGIAN TUTKIMUSKESKUS VTT";"DK;UK;NL;FI;DE;CH;IL";"/EDU;/NET";1;0;0;2;0;0 94449;249658;LIVEDIFFERENCE;ONG;FP7-IDEAS-ERC;ERC-AG-SH3;FP7;Living with Difference in Europe - Making Communities out of Strangers in an era of super-mobility and super-diversity;2010-06-01;2014-05-31;;"We are witnessing unprecedented levels of mobility (within and beyond the European Union) and population change. In this context, how we develop the capacity to live with difference is the key question of the 21st century. It is this fundamental research question which this proposal addresses (an issue that is particularly pertinent given rising levels of insecurity generated by post 9/11 terrorism and the current global financial crisis). This will be achieved by the generation of a new body of information and understanding about the extent and nature of everyday encounters with difference through five inter-linked projects, each collecting original empirical data in the UK and Poland. My vision is to advance the theorization of meaningful contact by using this data about spatial practices of encounter and intersectionality to shed new light on mostly unevidenced interdisciplinary theories of cosmopolitanism; and to develop further an innovative social topographic approach for transcending conventional comparative research perspectives by producing a sophisticated model of the complex webs of connection across the research locations, integrating the findings from a post-colonial and post-communist state. I will develop new horizons in methodological practice through the development of biographical timelines, and audio diaries to capture qualitative longitudinal data; video-elicitation of encounters with difference; and radical spatial experiments to create meaningful contact. The findings will provide an integrated evidence base about everyday understandings of difference and spatial practices of encounter that will inform, and nuance, European policies and strategies for living with difference. This programme will be unique internationally and will open up new directions in the interdisciplinary study of cosmopolitanism.";2181400;2181400;ERC-2009-AdG;/ERC-AG;THE UNIVERSITY OF SHEFFIELD;UK;UNIVERSITY OF LEEDS;UK;"/REG;/ENV;/SOC";1;0;0;2;0;0 109507;608133;PHOQUS;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-ITN;FP7;PHOtonic tools for Quantitative imaging in tissUeS;2013-11-01;2017-10-31;;'The PHOtonic tools for Quantitative imaging in Cells and tissUeS IDP (PHOQUS) will seed a revolution in the development and application of novel imaging modalities and multimodalities to enable the quantitative investigation of biological processes at multiple size regimes from the molecular and cellular to the tissue and organ level scale , by training graduate Physicists and Biologists for the first time to integrate seamlessly photonics, nanotechnology, advanced spectroscopy and novel spectral regions with the latest advances in imaging and diagnostics technology. The photonics focus on new tools and sources will open up opportunities to investigate the mechanisms and nuclear dynamics that control spindle formation and chromosome separation during mitosis as well as cell migration dynamics and mechanics during early embryonic development and the development of cancer in the gut. This will provide a strong interdisciplinary component to the training programme, linking Dundee’s extensive and world-class expertise in Life Science and pioneering work in the Medical School. The training programme will lead automatically to advances and new knowledge on how to harness these new technologies, and new strategies. PHOQUS is strongly intersectoral, with close involvement of 10 Associated Industrial Partners and 9 Academic distributed over 7 European countries. Imaging science is key for the success of any fundamental or applied research programme aiming to uncover the complexities of the life at multiple scales and to finding new solutions to diseases and conditions. By developing ESRs as a cohort they will avoid becoming isolated in between physics and biology, developing a true identity as interdisciplinary scientists: essentially 'problem oriented physicists” or 'solution oriented biologists'. PHOQUS aims to develop researchers with the correct mindset to discover and address the big problems in biology from an early stage in their research careers.';3816691,12;3816691,12;FP7-PEOPLE-2013-ITN;/MC-ITN;UNIVERSITY OF DUNDEE;UK;;;/LIF;1;0;0;2;0;0 185429;340331;EGO-MEDIA;ONG;FP7-IDEAS-ERC;ERC-AG-SH5;FP7;Ego-media: The impact of new media on forms and practices of self-presentation;2014-05-01;2019-04-30;;"Ego-media: The impact of new media on forms and practices of self-presentation This project aims to study the impact of new media on autobiographical narratives: an impact increasing as habits and practices of self-presentation evolve rapidly in response to constantly fast-changing technology. It will analyse the range of ways in which autobiographical forms and discursive practices are being transformed at the frontier of technological change; then consider the implications of the new forms and practices for such notions as autobiography, selfhood, subjectivity, individuality, self-intelligibility, agency, creativity, privacy, and sociability. Based in the interdisciplinary Centre for Life-Writing Research in the School of Arts and Humanities at King’s College London, it will combine a humanistic, life-writing theory approach with an interdisciplinary methodology, in collaboration with researchers from Sociolinguistics, Culture Media and Creative Industries, Digital Humanities, Medical Humanities, Psychiatry, War Studies, and Education. Keywords: Life-writing, Self-Presentation, Autobiography, Subjectivity, Agency, New Media, Social Media, Immediacy, Discourse, Digital Narratives, Internet, Web 2.0";2206994;2206994;ERC-2013-ADG;/ERC-AG;KING'S COLLEGE LONDON;UK;;;/SOC;1;0;0;2;0;0 107986;328967;THEORY/BODY/POST;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IOF;FP7;"The Post-Theory Moment of Body: Re-materializing the Corporeal, Bridging Critical Idioms, Conceptualizing Art";2014-01-02;2017-11-15;;"This project seeks to study the role, uses and transformations of the body within the contemporary reflection on post-Theory. It builds on contemporary work on post-Theory and on body-related issues in Anglo-American academic context, and it opens up to the French post-Theory movement, the German Kulturwissenschaft, philosophical life-narratives, body-oriented art discourses, and theoretical reflection on the senses. The project examines the body as a perpetually re-theorized political entity, as a common denominator of different types of literary and cultural criticism, and as a way of overcoming the divide not only among academic discourses, artistic practices and textual genres, but also between different intellectual traditions. The issues the project investigates range among the following: How is the body construed in the current post-theoretical phase of the humanities? Is reflection on the body a strategy shared by different post-theories? What does post-Theory gain or lose through its preoccupation with the body? To what extent does the body facilitate post-Theory’s mingling with explicitly political issues? Is this a convenient way to interdisciplinarity? How does the theorized body relate to the biological body and its senses? And in what ways is it reminiscent of its continued remodeling through art? In order to grapple with such issues, the project reads across a number of corpora: fundamental theoretical texts, as well as the vulgate of body studies, Readers, Histories and Introductions to Cultural Studies; texts “parasitic” to artworks’; philosophical life-narratives; seminal texts about the senses from the philosophy and the hard sciences. The analysis is based on systematic close readings, as well as on combined approaches and contextualized interpretations in an interdisciplinary and meta-theoretical perspective. It aims to address the specificity of each corpus, historicize it, and propose a narrative of the post-Theory moment of the body.";327410,9;327410,9;FP7-PEOPLE-2012-IOF;/MC-IOF;UNIVERSITY OF CYPRUS;CY;;;/LIF;1;0;0;2;0;0 97707;265970;ARCADE HSSR;ONG;FP7-HEALTH;HEALTH.2010.3.4-3;FP7;African Regional Capacity Development for Health Systems and Services Research;2011-04-01;2015-03-31;;"This project will add new research training capacity at Sub Saharan African (SSA) universities, for health systems and services strengthening. The focus is doctoral and post doctoral training, institutional strengthening for education, financial and administrative research management, and South-South network building. Novel capacity building approaches will reduce brain-drain, be more climate friendly and encourage gender equity with south based training. Internet mounted downloadable modules in quantitative (e.g., epidemiology), qualitative (e.g., anthropology) and economic methods will support excellent interdisciplinary courses. Our EU and African partners have many successful previous collaborations, e.g., web based training modules; joint PhD degree with Uganda. Health systems strengthening is research intensive, incremental improvement to service delivery, implementation and evaluation. Therefore SSA countries need to grow their own health services and systems research (HSSR) capacity: interdisciplinary, rigorous and relevant. ARCADE-HSSR will support evidence informed service delivery by producing a stream of well trained young HSSR scientists, the next generation of health system leaders and researchers in SSA. Activities will be aimed at individuals, institutions and at the network. Makerere University(MU) and Stellenbosch University (SU) are two strong SSA universities with HSSR focus. They will act as hubs in a South-South network including MU, SU, and initially, Muhimbili (MUH) and Malawi (MA). Working with strong northern HSSR institutions (Karolinska Institute KI, Sussex University Institute for development Studies, IDS, and Norwegian Knowledge Centre for Health Services KS) this region-wide approach will draw skills, resources and students to a new south-south HSSR capacity development network. We will expand our unique north-south joint PhD degree programme (KI-MU: 20 Ugandan graduates), to south-south joint PhD degrees (MU-SU).";2193184,2;1978424;FP7-AFRICA-2010;/CSA-CA;KAROLINSKA INSTITUTET;SE;"UNIVERSITY OF MALAWI;INSTITUTE OF DEVELOPMENT STUDIES;MUHIMBILI UNIVERSITY OF HEALTH AND ALLIED SCIENCES;MAKERERE UNIVERSITY;NASJONALT KUNNSKAPSSENTER FOR HELSETJENESTEN;STELLENBOSCH UNIVERSITY";"MW;UK;TZ;UG;NO;ZA";"/REG;/MED;/MBI";1;0;0;2;0;0 111134;327060;MEREDITH HANMER;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IEF;FP7;Meredith Hanmer;2014-11-17;2016-11-16;;The project studies the life and works of Meredith Hanmer (1543-1604), a historian of Welsh descent whose fascinating track record as a clergyman, controversialist, scholar and converter of Turks still awaits investigation. Through (a) archival research and the assessment of documentary evidence, (b) historical and biographical enquiry and (c) the textual analysis and critical appraisal of his written production, I intend to fill a research vacuum by producing an accurate and historically timely biography of this interesting figure thus contributing to the reconstruction of the intellectual panorama of early modern Britain. The complexity of Hanmer's figure makes the research inherently interdisciplinary and the heterogeneity of primary sources – manuscript and print, historical and literary, comprising translations, history writing, pamphlets and sermons – will require the combination of differing research methodologies, thus making the project an ideal gateway for the exploration of new interdisciplinary linkages between research fields. Further, Meredith Hanmer’s colourful career is particularly well-suited to engage an audience beyond academia with scholarly research and with the study of the cultural, social and political implications of the activity of a learned figure of the past. Finally, the focus on the work and life of an early modern English intellectual will provide an avenue for collaboration between European scholarly communities devoted to the study of the early modern English language, literature and culture, and undertaking such a project within the mobility experience of a IEF fellowship will foster international networks of excellence towards the development of collaborative linkages for research dissemination.;221606,4;221606,4;FP7-PEOPLE-2012-IEF;/MC-IEF;THE UNIVERSITY OF SUSSEX;UK;;;/SCI;1;0;0;2;0;0 97686;255082;EARLY SHAKESPEARE;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IIF;FP7;Shakespeare and the 1590s Style;2011-01-01;2012-12-31;;"The project explores how the early style of Shakespeare's dramatic and non-dramatic works written before 1595, which remains one of the least explored areas in Shakespeare studies, was shaped through a range of influences that came from withing England, European tradition of rhetoric, and classical sources. Critics have often thought of that style in terms of form (language) only, not as a product of a complex interplay of historical, political, ideological, and artistic influences brining 'modernity' England. However, a comparative analysis of the style of Shakespeare's early works within the historical context, modern literary and critical theories, especially an interdisciplinary research involving rhetoric (language and style), history, religion, and visual arts (sculptures and paintings), and the contemporary theories of identity, performance, and nation formation will show that Shakespeare's early style was far more 'European' and 'humanist' in origin than it has been hitherto assumed because he relied heavily on two traditions available to him: one was the persistent influence of the classical and European humanist literature on the English tradition in the 1590s (the most important decade in the emergence in the formation of English literature) and the growing import of European style in the visual arts and architecture in England, which became apparent in London, when Shakespeare arrived there. I propose to write a monograph on this topic, and a major academic publisher in the UK has already expressed an interest in it, and I plan to organize an international conference at UC Cork and publish a volume of essays based on that conference. The study aims to develop a comparative and European approach to interpreting Shakespeare's early style as well as the idea of 'early' style in the aesthetics of the 1590s. One key aspect will be to use interdisciplinary and comparative approach to explore the differing European appraoches to stylistic formation.";232082,8;232082,8;FP7-PEOPLE-2009-IIF;/MC-IIF;UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK;IE;;;"/SCI;/EDU;/ITT";1;0;0;2;0;0 110124;618511;ARTIAC;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-CIG;FP7;The Affective Role of the Teachers in the Information Age Classroom;2013-10-01;2017-09-30;;'The suggested project (ARTIAC) will be carried out under the interdisciplinary field of the Learning Sciences, and will use various research methodologies, including state-of-the-art Learning Analytics and Educational Data Mining approaches. Its main purpose is to empirically study the changing role of the teacher in an era where software used in class might be capable of recognizing not only a pupil’s academic level and needs, but also the pupil’s emotional regularities and irregularities. With this kind of information – and as teachers have crucial role in promoting an affective investment on the part of their pupils – it should be examined if teachers are to change the focus of their attention in computer-based classes towards supporting their pupils with meaningful and timely affective support. The project will explore this change of focus, and will supply teachers with efficient technological tools to support them in their affective decision-making in real-time. By its nature – combining concepts, models, and methods from Education, Psychology, Computer Science, Engineering, and others – this project is truly interdisciplinary.';100000;100000;FP7-PEOPLE-2013-CIG;/MC-CIG;TEL AVIV UNIVERSITY;IL;;;/LIF;1;0;0;2;0;0 110118;618277;JUDGEPOL;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-CIG;FP7;"""Judging Political Violence: Histories, Norms and Contestations""";2013-10-01;2017-09-30;;'This research project aims to advance Political Theory’s contribution to the interdisciplinary study of political violence. The 21st century presents us with new forms of political violence that challenge our moral and cognitive capacities. Faced with controversies over genocide, terrorism, and torture, scholars must both reflect on what is actually happening and offer guidelines about how to alleviate the harm. Yet, the academic field in Political Theory appears to be at a standstill. Torn between an intransigent moralism and a complacent realism, it does not offer useful tools for grasping the fluid nature of violence and for re-imagining our world as a better place. While moralists overemphasize the binding force of ethical principles in political decision-making, realists state that no definition of genocide, terrorism and torture can be shielded from abuse and manipulation. And whereas moralists lose sight of what actually motivates people to engage in politics, realists insist that there are no evaluative standards external to politics. Building on insights from the philosophy of judgment and the pragmatist tradition, I will sketch a normative middle position between moralism and realism. The project’s main goal is to work towards a reinvigorated Political Theory, one that recognizes the guidance of ethical principles without disregarding real politics. This goal will be reached through a pragmatically grounded account of judgment. A set of case studies from a variety of contexts will supplement the theoretical work. While the project aims to contribute primarily to Political Theory, its approach is interdisciplinary in nature. The project will also benefit from a variety of dissemination measures, which will creatively combine academic knowledge production, institutional recommendations and outreach activities. These measures will deepen the project’s impact on civil society and decision-makers.';100000;100000;FP7-PEOPLE-2013-CIG;/MC-CIG;THE UNIVERSITY OF EDINBURGH;UK;;;/LIF;1;0;0;2;0;0 93015;235741;NLNET-DYN;ONG;FP7-PEOPLE;FP7-PEOPLE-IOF-2008;FP7;Towards a comprehensive mathematical description of the Dynamics of Nonlinear Networks. Applications in System Biology;2009-09-01;2011-08-31;;A strong demand has been recently expressed in many disciplines of the European scientific area for the interdisciplinary development of modelling approaches to complex systems. A system is said to be complex when the knowledge of every individual is not enough to apprehend its global behaviour, and the effects of collective interactions need to be incorporated. Modelling approaches consist in establishing models and in studying their behaviours by various techniques. Mathematical techniques offer a rigorous way to describe robust phenomena and identify essential characteristics. Nonlinear networks are the generic models of complex systems. A central issue in their theory is to mathematically address the dynamics in arbitrary regimes of individual and collective factor strengths. So far, this problem has only been partly solved, in extreme regimes. Our project aims to provide a comprehensive mathematical picture. The main training objective is to gain expertise and to develop the necessary techniques, especially the abstract theory of non-uniform hyperbolic dynamical systems. The return phase also includes applications to concrete examples of regulatory networks in System Biology. The outgoing host group has been chosen according to its excellence in the field, especially its expertise in bridging theory and applications. The research experience in US will bring the complementary skills (project management, mentoring, etc) needed to attain a leading independent position in the return host. By proving new conceptual functioning schemes in original situations, the project will contribute to the European endeavour on complex systems which has recently been fostered by the creation of interdisciplinary institutes in EU. As to System Biology, the project will contribute to theoretical foundations of clinical gene therapy as a new approach to the treatment of diseases. In particular, this is relevant to Human Health theme of FP7 collaboration programme.;119180,76;119180,76;FP7-PEOPLE-IOF-2008;/MC-IOF;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FR;;;"/COO;/EDU";1;0;0;2;0;0 104620;318944;CONTESTED_CITIES;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IRSES;FP7;Contested Spatialities of Urban Neoliberalism: Dialogues between Emerging Spaces of Citizenship in Europe and Latin America;2012-10-01;2016-09-30;;Neoliberal ideologies applied in city politics can be portrayed as key aspects for the progressive and often conflictive transformations of urban space today. Such transformations do not exclusively apply to the political sphere – neoliberalism has also affected the habits of how people imagine, perceive and appropriate urban spaces in their daily life. Cities play a strategic role in the variegated geographies of neoliberalism, but relatively little research critically assessed the challenges citizenship faces in neoliberal societies. The interdisciplinary exchange programme CONTESTED_CITIES will tackle this gap – it investigates the discourses and practices of contest and re-appropriation of urban space, thus providing a novel understanding of how opposition against neoliberal urban development is being re-framed in the course of the current financial and economic crisis. It will bring together scientists from European and Latin American universities to discuss some of the striking consequences of urban neoliberalism and the resistance originated in different geographical backgrounds. By applying innovative qualitative methodologies such as reflexive photography and other visual accounts, the project aims at providing theoretical advances within citizenship studies and urban geography as well as at producing new empirical insights to the consequences of recent urban policies. Within an interdisciplinary network to analyse and compare urban policies, gentrification and contestation in Europe and Latin America, the exchange programme creates additionally the conditions to introduce policy transfer by learning from Latin American cities - which have experienced for decades urban conflict and highly innovative urban solutions - as laboratories of social change, and to create a theoretical background that overcomes existing lacunas between urban debates in the English, and the Spanish and Portuguese-speaking literature.;793800;793800;FP7-PEOPLE-2012-IRSES;/MC-IRSES;UNIVERSIDAD AUTONOMA DE MADRID;ES;UNIVERSITY OF LEEDS;UK;/SCI;1;0;0;2;0;0 104698;316488;KESTCELLS;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-ITN;FP7;Training for sustainable low cost PV technologies: development of kesterite based efficient solar cells;2012-09-01;2016-08-31;http://kestcells.eu/;"The overall objective of this project is the creation of an ITN network for the structured interdisciplinary training of researchers in advanced thin film photovoltaic (PV) technologies. The project proposes the development of new technologies compatible with the cost, efficiency, sustainability and mass production requirements that are needed to become a reliable and future alternative to conventional non renewable energy sources. With this objective in mind, the project will focus on the development of kesterite based solar cells. Kesterites are quaternary compounds with a crystalline structure very similar to that of chalcopyrites (CIGS: Cu(In,Ga)(S,Se)2). They have a strong potential for thin film low cost PV technologies, related to their direct bandgap and high optical absorption. In contrast with CIGS -where the potential for high mass production is compromised by the scarcity of In- they are constituted by abundant elements. For this, a consortium formed by research institutes, universities and companies with strongly complementary expertises has been formed. This includes groups that are leaders on the development of kesterite cells (Univ. Northumbria, HZB, Univ. Luxembourg) with groups with strong expertise on CIGS technologies (that are the parent technologies for kesterite solar cells) (EMPA, UU-ASC, NEXCIS, IREC, Free Univ. Berlin, Univ. d'Aix-Marseille, Autonomous Univ. Madrid). Free Univ. Berlin has also significant experience in the crystalline analysis of kesterites. Involvement of private companies (NEXCIS, Abengoa) devoted to the production and exploitation of PV technologies provides with complementary training aspects related to transferability of processes to industrial production and exploitation issues. All these aspects are relevant for the definition of a structured interdisciplinary training programme for the formation of high level researchers that will be required in Europe for the development of competitive PV technologies.";3705320,08;3705320,08;FP7-PEOPLE-2012-ITN;/MC-ITN;FUNDACIO INSTITUT DE RECERCA DE L'ENERGIA DE CATALUNYA;ES;"UPPSALA UNIVERSITET;UNIVERSITY OF NORTHUMBRIA AT NEWCASTLE;UNIVERSITE DU LUXEMBOURG;HELMHOLTZ-ZENTRUM BERLIN FUR MATERIALIEN UND ENERGIE GMBH;ABENGOA SOLAR NEW TECHNOLOGIES SA;UNIVERSITE D'AIX MARSEILLE;UNIVERSIDAD AUTONOMA DE MADRID;NEXCIS;FREIE UNIVERSITAET BERLIN;EIDGENOSSISCHE MATERIALPRUFUNGS- UND FORSCHUNGSANSTALT";"SE;UK;LU;DE;ES;FR;CH";/LIF;1;0;0;2;0;0 102934;303848;MECPATH;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-CIG;FP7;Mechanical pathways in cells: from molecular mechanisms to cell function;2012-09-01;2016-08-31;;How cells detect and respond to mechanical stimuli from their surroundings determines key processes in development, tumor formation and wound healing. However, while some molecules have been identified to possess mechanosensing capabilities, the molecular mechanical links by which cells withstand, transmit and detect forces remain unknown. In an analogy to the well-known concept of molecular biochemical pathways, we define this biophysical network of mechanical links as “molecular mechanical pathways”. We hypothesize that the molecules most likely to be directly experiencing forces applied from the extracellular matrix, which are the proteins that link extracellular matrix (ECM) receptors (integrins) to the actin cytoskeleton, are key components of these pathways. To our knowledge, only four such proteins, possessing binding sites to both integrins and actin, have been identified. These are talin, alpha-actinin, filamin, and tensin. I thus propose an interdisciplinary project aimed at identifying how talin, alpha-actinin, filamin, and tensin form the dynamic molecular pathways that communicate cells mechanically with their environment. In objective 1, a novel magnetic tweezers device and Atomic Force Microscopy will be employed study the role of these proteins in detecting, withstanding, and transmitting forces from the ECM. In objective 2 dynamic force protocols will be employed to determine the impact of real-life constantly changing cellular forces on these mechanical pathways. In objective 3, the molecular mechanisms behind these pathways will be elucidated by combining Fluorescence Resonance Energy Transfer (FRET) microscopy with AFM and observing how mechanical stimuli regulate protein stretching and binding. While the methods proposed and scientific questions addressed present important challenges, a robust interdisciplinary expertise in the techniques involved and a solid achievement record in the field support the feasibility of the project.;100000;100000;FP7-PEOPLE-2011-CIG;/MC-CIG;UNIVERSITAT DE BARCELONA;ES;;;/SCI;1;0;0;2;0;0 103666;297855;QUANTUM4BIO;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IIF;FP7;Quantum Optics Tools for Biomedical Imaging;2012-06-01;2014-05-31;;"'Two-photon fluorescence microscopy has evolved to one of the most powerful tools in biological imaging, especially in the field of neuroscience. It provides improved depth penetration and reduced photo-bleaching of fluorophores and has thus enabled three dimensional structural and functional imaging of biological samples. However, in typical media and with uncorrelated (classical) photons, the two-photon absorption (TPA) process has small interaction strengths and therefore requires large optical intensities, which can lead to photo-damage in the media or prohibit its use with highly light sensitive biological samples. In this fellowship, we will address this shortcoming by using the process of entangled two-photon absorption (ETPA). Due to the energy-time correlation of entangled photon pairs, the effective cross-section, and therefore the efficiency of the absorption, can be increased by many orders of magnitude. This represents a fundamentally new approach to microscopy and if successful, will have a significant impact on fundamental and applied biology, as it allows for imaging and probing biological processes in a highly non-invasive fashion. For this project, we aim to design and build an entangled photon source engineered for optimal ETPA and identify ideal molecules that can function as labels and fluorescent proteins in biological samples. This highly interdisciplinary project will combine and exploit advantages of quantum optics and two-photon fluorescence microscopy and pave the way for novel, entanglement-based biological imaging and spectroscopy tools. This highly interdisciplinary project will combine the candidate’s expertise in quantum optics and quantum information with the host’s extensive background in bio-medical imaging. This fellowship will catalyze a significant development in the candidate’s career and enable him to attain a leading independent position in this new field at the interface of quantum physics and biology.'";180191,4;180191,4;FP7-PEOPLE-2011-IIF;/MC-IIF;UNIVERSITAT WIEN;AT;;;/SCI;1;0;0;2;0;0 101684;291728;ERASYNBIO;ONG;FP7-KBBE;KBBE.2011.3.6-06;FP7;Development and Coordination of Synthetic Biology in the European Research Area;2012-01-01;2014-12-31;http://www.erasynbio.eu/;"Synthetic biology is an emerging and promising research area with the potential to have a strong impact on innovation and technological progress that is beneficial for the economy and for society as a whole. It is an area at the intersection of engineering, bioscience, chemistry, and information technology. The central idea of ERASynBio is to promote the robust development of synthetic biology by structuring and coordinating national efforts and investment. ERASynBio will develop a white paper (WP1), which will support the emergence of national synthetic biology programmes and which will lay the ground for transnational funding activities via joint calls in the project (WP6). ERASynBio will stimulate and tackle the interdisciplinary nature and immaturity by offering training and educational possibilities (WP4), establishing an interdisciplinary advisory board and inviting observers of other funding organisations. It will further provide extensive dialogue options (WP1-5) and exchange fora (WP3) for the scientific community. Close collaboration between academia and industry aiming to fertilize the innovation process will occur on several levels (WP1, WP3, WP6). To adhere to ethical, legal and societal aspects as well as to technical issues like standardisation and infrastructure development ERASynBio will trace and integrate the ongoing work and research on these framework conditions and integrate them in the white paper (WP2 and WP5). It is a challenge for the ERA-Net to successfully coordinate the newly emerging activities in this field as only a few partners have fully developed national programmes for synthetic biology. Thus it is the aim to create the ERA of synthetic biology in parallel with the development of the scientific community. It is the first time a truly European research community can be build almost from the beginning of its development.";2350282,6;1997022;FP7-ERANET-2011-RTD;/CSA-CA;FORSCHUNGSZENTRUM JULICH GMBH;DE;"NEDERLANDSE ORGANISATIE VOOR WETENSCHAPPELIJK ONDERZOEK;STYRELSEN FOR FORSKNING OG UDDANNELSE;GENIKI GRAMMATIA EREVNAS KAI TECHNOLOGIAS;EIDGENOESSISCHES DEPARTEMENT FUER WIRTSCHAFT, BILDUNG UND FORSCHUNG;MINISTERIO DE CIENCIA E INNOVACION;LATVIJAS ZINATNU AKADEMIJA;BUNDESMINISTERIUM FUER BILDUNG UND FORSCHUNG;MINISTERIO DE ECONOMIA, INDUSTRIA Y COMPETITIVIDAD;SUOMEN AKATEMIA;NORGES FORSKNINGSRAD;BIOTECHNOLOGY AND BIOLOGICAL SCIENCES RESEARCH COUNCIL;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;MINISTRSTVO ZA VISOKO SOLSTVO, ZNANOST IN TEHNOLOGIJO;AGENCE NATIONALE DE LA RECHERCHE;OESTERREICHISCHE FORSCHUNGSFOERDERUNGSGESELLSCHAFT MBH;FUNDACAO PARA A CIENCIA E A TECNOLOGIA";"NL;DK;EL;CH;ES;LV;DE;FI;NO;UK;FR;SI;AT;PT";/LIF;1;0;0;2;0;0 102132;269256;MSLIFE;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-IRSES;FP7;Integrating high performance mass spectrometry tools with application in life science;2011-11-01;2014-10-31;;"Recent advances of biopolymer mass spectrometry - first highlighted by the Nobel Prize-awarded “soft ionization” methods - have opened new applications in life sciences, such as the identification of proteins from complex biological material (proteomics). A number of high performance mass spectrometry technologies and hyphenated separation methods have become amenable; however, their efficient exploration and integration in interdisciplinary biochemical and biomedical applications is still in the initial phase. In this project an effective exchange scheme of staff will be established between European laboratories of different application areas, and leading American Centers of high performance biopolymer mass spectrometry. Joint research projects through exchange of coworkers will focus on the determination of protein structures and pathophysiological structure modifications; the identification of the assembly and topology of large protein complexes; development and application of disease-related quantitative proteome analysis; characterization of protein conformations and misfolding/aggregating proteins; applications to elucidate protein-biopolymer interactions and molecular recognition structures using new tools of bioaffinity-mass spectrometry. The principal goals of this project are (i), to establish new technologies of mass spectrometry in important life science applications such as the identification of biomarkers for disease diagnostics; and (ii), to provide a basis, through exchange of coworkers, for the integration of mass spectrometry tools with biochemical and biomedical technologies. This project will contribute to (i), integrate interdisciplinary applications of biopolymer mass spectrometry in life sciences; (ii), enhance exchange and collaboration between European and North-American academic laboratories; (ii) the graduate and postgraduate education of young researchers in mass spectrometry in life sciences.";319200;319200;FP7-PEOPLE-2010-IRSES;/MC-IRSES;UNIVERSITAT KONSTANZ;DE;"SYDDANSK UNIVERSITET;UNIVERSITAET ROSTOCK;UNIVERSITEIT UTRECHT;UNIVERSITATEA AUREL VLAICU DIN ARAD";"DK;DE;NL;RO";"/EMP;/SOC";1;0;0;2;0;0 97644;263747;CROSSROADS;ONG;FP7-IDEAS-ERC;ERC-SG-SH6;FP7;Crossroads of empires: archaeology, material culture and socio-political relationships in West Africa;2011-01-01;2015-12-31;;"Knowledge of the last 1000 years in the West African Sahel comes largely from historical sources, which say that many regions were ruled by vast polities. The aim of my archaeological project is to seize how, in fact, lhe 'empires' of this region structured the landscape, and the movemenl of peoples, ideas, and things, with a focus on the period AD 1200-1850. Is 'empire' really a useful term? I will confront historical evidence with archaeological data from one area at the intersection of several polities: the dallols in Niger. This area is rich in remains, said to result from population movements and processes of religious and political change, but these remains have been only briefly described so far. As this region is a key area of migrations and cross-influences, it is the ideal 'laboratory' for exploring the materialisation of contacts and boundaries, through a mapping of material culture distributions. My project will approach these sites holistically, carrying out archaeological regional survey and prospection. Excavation will indicate chronology and cultural affiliation. At lhe same time, I will take an interdisciplinary approach, using anthropological and oral-historical enquiries to obtain background information to test hypotheses generated by the archaeological data. Enquiries will assess how material culture can show group belonging and population shifts, and examine the role of individuals called 'technical specialists'. This will help solve the current impasse in our understanding of vast empires which, though they are historically known, remain poorly understood. My project will not just improve our knowledge of an almost-unknown part of the world, but thanks to its geographical location, interdisciplinary nature and strong thematic framework, open up avenues of thinking about the relalion between archaeological and historical data, the mediation of relations through artefacts, and the archaeology of empires, all widely-relevant research issues";893161;893161;ERC-2010-StG_20091209;/ERC-SG;UNIVERSITY OF EAST ANGLIA;UK;"UNIVERSITE D ABOMEY CALAVI UAC;University Abdou Moumouni;UNIVERSITE LIBRE DE BRUXELLES;MUSEE ROYAL DE L'AFRIQUE CENTRALE;THE UNIVERSITY OF STIRLING";"BJ;NE;BE;UK";"/SCI;/SOC";1;0;0;2;0;0 102704;304099;LARGEFLOWVIS;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-CIG;FP7;Large Scale Flow Visualization and Analysis;2012-04-01;2016-03-31;;"Scientific visualization of large-scale vector fields with modern, so-called integration-based methods that rely on the analysis of particle trajectories is not feasible with current methods, since existing algorithms cannot make efficient use of parallel architectures such as clusters and supercomputers. This status leaves researchers in science and industry unable to visualize, analyze and understand the processes described by large vector field data from simulation or measurement. The proposed CIG project aims at developing a novel methodological framework for integration-based visualization that will provide visualization of largest-scale vector fields in current scientific applications. The novel methodology will allow the efficient use of parallel architectures for fast and interactive visualization of very large vector field data sets, which is not possible with current methods. The project’s approaches will combine techniques from scientific visualization, parallel algorithms, applied mathematics, and software design. The resulting increased ability to study large vector fields will strongly impact fundamental scientific research in a large and interdisciplinary setting of scientific and industrial application areas that rely on vector field visualization. This includes research on technologies related to timely problems such as combustion, fusion, and aerodynamics, where technological improvements due to an increased understanding of vector field processes will benefit to the “Resource Efficient Europe” flagship initiative of the Europe 2020 strategy.. The novelty, interdisciplinary nature and expected impact of the proposed research will increase the EU’s excellence, and the applicants teaching activities will train young researchers exposing them to cutting-edge research. Thus, the proposed project leads to knowledge transfer into the ERA, long-term re-integration of a European researcher, and introduction of a promising new research field in Europe.";100000;100000;FP7-PEOPLE-2011-CIG;/MC-CIG;TECHNISCHE UNIVERSITAET KAISERSLAUTERN;DE;;;/SCI;1;0;0;2;0;0 94747;254139;ICARUS;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IEF;FP7;Ionospheric threats and suitable Countermeasures Applicable to satellite Radio systems Under next Solar maximum;2010-06-01;2012-05-31;;The fellow is Assistant Professor in Physics at the the Centre for Atmospheric Research, University of Nova Gorica, Slovenia. He specialises in physics of the upper ionised atmosphere, radio wave propagation and remote sensing of the atmosphere. The scientific training focuses on the study of the upper ionised atmosphere (ionosphere) and its effects on Global Navigation Satellite Systems (GNSS), such as GPS and the new European Galileo, during next solar maximum. This will also benefit the reliable operation of the European Space Situational Awareness service. The fellowship will provide specific training in Geodesy, GNSS techniques and services, not available in Slovenia but inherent to the expertise of the Institute of Engineering Surveying and Space Geodesy (IESSG) at the University of Nottingham. The candidate’s background is entirely disparate and complementary to the existing expertise at the IESSG, making this a truly interdisciplinary and collaborative venture. The fellowship will advance the scientific and academic career of the fellow once he is back at UNG, enhancing his ability to train future students and scientists in GNSS related sciences and ultimately his career prospects. He aims to establish an international centre of excellence in Slovenia. The training is by nature interdisciplinary and achieving its scientific goals will depend on a solid understanding of fields that are mastered either by the fellow or the host institution. Very importantly, the advancement of the candidate’s career will be also underpinned by additional training in areas such as management of large projects, interaction with high calibre scientists and with industry, and international cooperation, The fellowship will possibly lead to patents and technological solutions to make European systems and services more robust and efficient, bringing economic advantages for companies in Europe involved in the design and commercialisation/provision of related GNSS receivers/services.;231927,2;231927,2;FP7-PEOPLE-2009-IEF;/MC-IEF;THE UNIVERSITY OF NOTTINGHAM;UK;;;"/SCI;/EDU;/ITT";1;0;0;2;0;0 96294;247503;EUJOINT;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IRSES;FP7;European Japanese Ontology Interaction;2010-03-15;2012-03-14;;"Uniting together four most prominent research centers acting at the intersection between engineering design, knowledge engineering, and philosophy of technology, EUJOINT will offer to Japanese and European researchers a unique opportunity for scientific exchange and focused cooperation on highly strategic, interdisciplinary projects. The four centres will exchange and integrate their knowledge with the goal of creating general engineering ontologies for technical products, accounting for functionality notions in a systematic, detailed, and cognitively transparent way. This goal is sought by focusing on four distinct yet interdependent objectives: (1) adoption of a common methodology for ontological analysis aiming at unifying core elements of the ontologies independently developed by members; (2) comparison and formalization of the various notions of role, action and agent exploited by members to capture product functionality; (3) clarification and formalization of the notions of artefact, device and product as employed in philosophy and in engineering design; (4) systematic study of the notion of engineering function (functionality), especially as used in engineering design, including the proper characterization of malfunctioning, and exchange of experiences on these and related notions in industry cases. EuJoint is unique since its members are internationally well known in their specialization areas and all embrace an interdisciplinary attitude that promotes interactions and synergies with groups in other disciplines. This shared attitude and the record of previous collaborations/meetings indicate the sincere commitment of each center to the programme and to an effective interaction. The centers are complementary concerning the knowledge needed and the objectives are of crucial importance for future generation product management systems, integrating CAD/CAM and life-cycle management with the early phases of engineering design.";21600;21600;FP7-PEOPLE-2009-IRSES;/MC-IRSES;CONSIGLIO NAZIONALE DELLE RICERCHE;IT;"KATOLICKI UNIWERSYTET LUBELSKI*CATHOLIC UNIVERSITY OF LUBLIN KVL;TECHNISCHE UNIVERSITEIT DELFT";"PL;NL";"/SCI;/EDU;/ITT";1;0;0;2;0;0 99981;293901;POEM;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-CIG;FP7;Perceptual Organization and Eye Movements;2011-09-01;2015-08-31;;"The process by which the brain transforms visual input into coherent objects is called perceptual organization. State-of-art research in this domain does not offer much insight into the bridge between the realm of perceptual organization and information acquired by eye movements, which consist of fixations that are discrete and serial. The project proposed here, “POEM”, is designed to bridge this research gap by investigating the connection between Perceptual Organization (PO) and Eye Movements (EM) at three levels of processing: explicit (ePOEM), implicit (iPOEM) and functional (fPOEM). Regarding the methodology POEM will record the eye-movement pattern while the participants perform tasks based on perceptual organization of the carefully constructed stimuli shown in experimental settings in the lab. The information gathered will be analyzed by correlation analyses followed by modelling of the behavioural and eye-movement data. POEM will result in - information metrics at fixation points that are used by our visual system for PO, - an implicit measure for the strength of grouping factors based on EM data and - the description of the relationship between spatial aesthetics and the ease of navigation of EM to various “preferred” positions in a visual display. POEM is interdisciplinary- it deals with important open issues in perceptual psychology by using tools of the engineering domain. Additionally, its outcome will have tremendous interdisciplinary impact, especially in the domains of user-interface design, data-visualization and consumer psychology. Networking within POEM illustrates how the researcher will integrate, intensify and expand her collaborations with the USA and within the EU advancing the EU’s scientific excellence as well as her research career. In a nutshell, POEM comprises knowledge transfer into the EU, the introduction of a novel research approach and the long-term integration of an international renowned researcher in perceptual science.";100000;100000;FP7-PEOPLE-2011-CIG;/MC-CIG;TECHNISCHE UNIVERSITAET KAISERSLAUTERN;DE;;;/SCI;1;0;0;2;0;0 99631;264633;DISSETTLE;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-ITN;FP7;Dispute Settlement in Trade: Training in Law and Economics;2011-05-01;2015-04-30;http://www.dissettle.org/;"DISSETTLE will train a cohort of economists and lawyers to work together on dispute resolution. It will focus on the disputes under the WTO Agreements, but will also deal with regional and bilateral trade agreements. It will bring together the European institutions that have pioneered interdisciplinary work on economics and law, and benefit from the experience of competition law, where collaboration between economists and legal experts is well-established. Training of ESRs and ERs will be carried out through a mix of activities at individual nodes and network-wide activities, including internships in private sector companies and international organisations, conferences, summer schools, workshops and complementary skills training. Participation of the WTO, law firms and consultancies will guarantee that research and the training are practical and interdisciplinary. Together the institutions and experts in the network will train a new cohort of legal and economic experts on economics in international trade law. The resolution of international trade disputes is of particular importance to the EU. 37% of the complaints filed at the WTO have involved the EU as the complaining or defending party, and the EU is now negotiating more bilateral, regional and multilateral trade agreements than ever before. America has already recognized the growing importance of international trade law. The American Law Institute has launched an ambitious project bringing together economists and lawyers to develop proposals to reform the WTO Agreement. Europe does not have such a critical mass of expertise, even though this area is vital to its economic interests. The proposed network, anchored by strong nodes in Brussels and Geneva, will help create the expertise that Europe needs.";2852687;2852687;FP7-PEOPLE-2010-ITN;/MC-ITN;FONDATION POUR L INSTITUT DE HAUTES ETUDES INTERNATIONALES ET DU DEVELOPPEMENT;CH;"UNIWERSYTET WARSZAWSKI;UNIVERSITA COMMERCIALE LUIGI BOCCONI;UNIVERSITE LIBRE DE BRUXELLES;UNIVERSITAET ST. GALLEN";"PL;IT;BE;CH";"/EDU;/NET";1;0;0;2;0;0 95284;255386;HUMANWOLFDOG;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IEF;FP7;Redefining wild-domestic boundaries in a changing landscape through the human-wolf-dog relationships;2010-05-15;2012-05-14;;"The political and economic changes of recent decades are having an impact on the European rural environment, resulting in conflicting situations around the recovery of habitats and wildlife species (often symbolised by the wolf) and rural communities. These conflicts are being addressed by the EU through technical and economical measures but there is a general failure to recognise the importance of their social and cultural aspects. Anthropology can contribute by highlighting the overall context and the complexity of factors affecting people's perceptions of wildlife and the rural landscape. Using a multi-disciplinary approach we will examine how the domestic dog, as a victim or as a mean of protection, modulates the man – wolf conflict. This will link anthropological conceptual models and concrete attempts to address material aspects of this conflict, and to use this case study as a lens to examine wider issues associated with how rural people perceive their relationship with the various elements of the landscape they inhabit. We will conduct fieldwork using innovative methodology, crossing the traditional anthropological qualitative approach with quantitative, spatial and visual ones borrowed from other disciplines. Moreover, a cross comparison between different landscape users coming from different regions (Poland, Norway and FYROM) will help illuminate the influence of the specific set of environmental and social / cultural circumstances. The combination between 1) the scientific quality of the host institution, focused on multi-disciplinary and applied research within the fields of biodiversity conservation, natural resource management and rural development and 2) the interdisciplinary profile of the applicant, experienced in anthropological theories and fieldwork, is relevant to develop multidisciplinary conflict research in Europe and advance the career of a competitive interdisciplinary researcher in more applied anthropology.";214072;214072;FP7-PEOPLE-2009-IEF;/MC-IEF;STIFTELSEN NORSK INSTITUTT FOR NATURFORSKNING NINA;NO;;;"/SCI;/EDU;/ITT";1;0;0;2;0;0 101260;289447;LINC;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-ITN;FP7;Learning about Interacting Networks in Climate;2011-12-01;2015-11-30;http://climatelinc.eu/;"Improving our understanding of the Earth’s climate phenomena, such as El Ni?o, has a huge economic and social impact for present and future generations, and can underpin advances in areas as diverse as energy, environment, agricultural, etc. There is a great shortage of qualified workforce to perform this task and a major challenge is the training of qualified researchers that can approach climate phenomena from a complex systems point of view. The ITN proposed here, ‘Learning about Interacting Networks in Climate’ (LINC) aims to address these issues by training 12 ESRs and 3 ERs in the complete set of skills required to undertake a career in physics and geosciences with expertise in climatology, networks and complex systems. We will combine recent advances in network methodologies with state-of-the-art climate understanding. The consortium, comprising of 6 academic partners, 3 SMEs and one associate partner (also an SME) is in an excellent position to impart these skills, with expertise ranging from complex systems (network construction, nonlinear time series analysis), and environment and geosciences (nonlinear processes in the oceans and atmosphere) up to commercial applications (climate risk analysis, using climate networks to predict extreme events). The skills to be imparted in each of the 5 WPs (Network Construction and Analysis, Interacting Networks, Natural Climate Variability, Future Climate Change, and Tipping Points in the Climate System) can be applied across a wide range of interdisciplinary fields. In LINC the training of researchers will be aided by secondments at the commercial partners’ premises, a series of workshops, schools and a conference. The strong commitment towards training and research of the partners will guarantee graduates with full interdisciplinary capabilities, that will allow them to significantly advance the present knowledge of climate phenomena, and which will provide them a wide-range of career opportunities.";3715523,97;3715523,97;FP7-PEOPLE-2011-ITN;/MC-ITN;UNIVERSITAT POLITECNICA DE CATALUNYA;ES;"Climate Risk Analysis - Manfred Mudelsee;UNIVERSIDAD DE LA REPUBLICA;POTSDAM INSTITUT FUER KLIMAFOLGENFORSCHUNG;BAR ILAN UNIVERSITY;VORTECH BV;AMBROSYS GMBH GESELLSCHAFT FUR MANAGEMENT KOMPLEXER SYSTEME;UNIVERSITAT DE LES ILLES BALEARS;UNIVERSITEIT UTRECHT";"DE;UY;IL;NL;ES";"/LIF;/SCI";1;0;0;2;0;0 98975;269295;EDUMEMS;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-IRSES;FP7;Developing Multidomain MEMS Models for Educational Purposes;2011-07-01;2016-06-30;;"Micro-electro-mechanical systems (MEMS) represents a modern field in engineering with a significant impact on industrial applications. By combining together electrical, mechanical, thermal and optical elements, MEMS revolutionize the market of sensors and actuators. Clearly, each discipline mentioned above is a long-established and thoroughly researched field. However, there are still many MEMS phenomena left to be explored. The reason is twofold: - MEMS are fabricated in the micrometer scale and microscale-related phenomena have not yet been fully researched - MEMS allow merging many disciplines together and, therefore, mutual dependencies in the microscale between previously unrelated domains are created. Thus, it leads to appearing new research areas when two or more domains meet. The complexity, multi-domain character and diversity of MEMS devices require the designers to specialize in several interdisciplinary domains in order to create a successful design. Currently, there are many research groups across Europe involved in one particular discipline. However, only few of them may have researchers specializing in all of them, which may limit or even impede MEMS research in Europe. Therefore, the primary objective of the project is to combine efforts of European research teams for the purpose of forming an international interdisciplinary group working on a project of a MEMS device (EduMEMS), which incorporates multi-domain phenomena. Each partner involved in the project specializes in at least one research field related to MEMS. The researchers from each domain will be sent to other partners to work on the project and organize courses and lectures related to their specialization. Each partner will then gain knowledge about the domain, which previously he has not specialized in. As a result, each partner should expand their narrowly-specialized research to other disciplines and become capable of performing multi-domain MEMS research independently.";279300;279300;FP7-PEOPLE-2010-IRSES;/MC-IRSES;POLITECHNIKA LODZKA;PL;"UNIVERSITEIT GENT;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;POLITECHNIKA WROCLAWSKA";"BE;FR;PL";"/EMP;/SOC";1;0;0;2;0;0 92990;241125;MOM;ONG;FP7-IDEAS-ERC;ERC-SG-SH6;FP7;The medicine of the mind and natural philosophy in early modern England: A new interpretation of Francis Bacon;2009-12-01;2014-11-30;;"The aim of the project is to provide a groundbreaking new interpretation of Francis Bacon's natural philosophy. The original aspect of this project will consist in a new contextualisation of Bacon's philosophy. We argue that his work can be seen as one of the most characteristic products of what we have decided to call, for reasons of heuristic and exegetical convenience, the medicine of the mind. This project is interdisciplinary in both the method we are going to apply and the object we are going to study, for this investigation represents a study on early-modern interdisciplinarity. The movement known as Renaissance Neostoicism, especially in its French version, will be a key element in our argument. The objectives of the project are, first, to provide an unconventional interpretative angle to the study of the transmission of Stoic ideas; second, to show their intertwinement with religious models of self-analysis and, most of all, to highlight the combined influence of Stoic and Reformed models of introspection on Bacon's natural philosophy. We argue that Stoic materialism, from its inception, entailed the view that human appetites could not be explained and tamed without connecting them to the very appetites of nature. Our reconstruction of varieties of British medicine of the mind, permeated by Stoic ideas, will throw much needed light on the way in which Bacon looked for a new method that could allow man to master both the appetites of matter and the appetites of society. In more general terms, our reconstruction of the British contexts of the medicine of the mind will provide a crucial missing link in the contemporary narratives of the scientific revolution.";899886;899886;ERC-2009-StG;/ERC-SG;UNIVERSITY OF LONDON;UK;FUNDATIA NOUA EUROPA;RO;"/SCI;/SOC";1;0;0;2;0;0 100690;281930;ARCADE RSDH;ONG;FP7-HEALTH;HEALTH.2011.3.4-2;FP7;Asian Regional Capacity Development for Research on Social Determinants of Health;2011-12-01;2015-11-30;http://www.arcade-project.org/rsdh/;"This project will add new research training capacity at low and middle-income countries (LMICs) in Asia, for promoting research on social determinants of health (RSDH). The focus is doctoral and post doctoral training, institutional strengthening for education, financial and administrative research management, and LMICs-based network building. Novel capacity building approaches will reduce brain drain, be more climate friendly and encourage gender equity with LMICs-based training. Internet mounted downloadable modules in related disciplines, like epidemiology, anthropology, economic methods, etc., will support excellent interdisciplinary courses. Addressing social determinants of health and tackling health inequity are research intensive, incremental improvement to measurement and understanding, implementation and evaluation. Therefore LMICs need to grow their own capacity to strengthen RSDH: interdisciplinary, rigorous and relevant. ARCADE-RSDH will support evidence informed decision making by producing a stream of well-trained young RSDH scientists, the next generation of health system leaders and researchers in LMICs. Activities will be aimed at individuals, institutions and the network. Tongji Medical College of HUST (TJMC, China), CBCI Society of Medical Education (SJNAHS, India) and Public Health Foundation of India (PHFI, India) are strong Asian Universities with RSDH focus. They will act as hubs in a network including TJMC, SJNAHS, PHFI, Beijing Normal University (BNU, China), Zhejiang University (ZJU, China), Indian Institute of Health Management Research (IIHMR, India), Ruxmaniben Deepchand Gardi Medical College (UCTH, India) and initially Sultan Qaboos University (SQU, Oman), Hanoi Medical University (HMU, Vietnam), working with strong European RSDH institutions (Karolinska Institutet KI, Sussex University Institutet for Development Studies IDS and University of Tampere UTA). This region-wide approach will draw skills, resources and students to a new LMICs-based RSDH capacity development network.";2201583,9;1996595;FP7-HEALTH-2011-single-stage;/CSA-CA;KAROLINSKA INSTITUTET;SE;"Hanoi Medical University;STIFTELSEN GAPMINDER;INSTITUTE OF DEVELOPMENT STUDIES;SULTAN QABOOS UNIVERSITY;TAMPEREEN YLIOPISTO;HUAZHONG UNIVERSITY OF SCIENCE ANDTECHNOLOGY;Zhejiang University;INDIAN INSTITUTE OF HEALTH MANAGEMENT RESEARCH SOCIETY;BEIJING NORMAL UNIVERSITY;UJJAIN CHARITABLE TRUST HOSPITAL & RESEARCH CENTRE;PUBLIC HEALTH FOUNDATION OF INDIA;CBCI Society for Medical Education;STELLENBOSCH UNIVERSITY";"VN;SE;UK;OM;FI;CN;IN;ZA";/LIF;1;0;0;2;0;0 97879;267700;INVPROB;ONG;FP7-IDEAS-ERC;ERC-AG-PE1;FP7;Inverse Problems;2011-03-01;2016-02-29;;"Inverse problems constitute an interdisciplinary field of science concentrating on the mathematical theory and practical interpretation of indirect measurements. Their applications include medical imaging, atmospheric remote sensing, industrial process monitoring, and astronomical imaging. The common feature is extreme sensitivity to measurement noise. Computerized tomography, MRI, and exploration of the interior of earth by using earthquake data are typical inverse problems where mathematics has played an important role. By using the methods of inverse problems it is possible to bring modern mathematics to a vast number of applied fields. Genuine scientific innovations that are found in mathematical research, say in geometry, stochastics, or analysis, can be brought to real life applications through modelling. The solutions are often found by combining recent theoretical and computational advances. The study of inverse problems is one of the most active and fastest growing areas of modern applied mathematics, and the most interdisciplinary field of mathematics or even science in general. The exciting but high risk problems in the research plan of the PI include mathematics of invisibility cloaking, invisible patterns, practical algorithms for imaging, and random quantum systems. Progress in these problems could have a considerable impact in applications such as construction of metamaterials for invisible optic fibre cables, scopes for MRI devices, and early screening for breast cancer. The progress here necessitates international collaboration. This will be realized in upcoming programs on inverse problems. The PI is involved in organizing semester programs in inverse problems at MSRI in 2010, Isaac Newton Institute in 2011, and Mittag-Leffler -institute in 2012.";1800000;1800000;ERC-2010-AdG_20100224;/ERC-AG;TALLINNA TEHNIKAULIKOOL;EE;HELSINGIN YLIOPISTO;FI;"/PSE;/MST";1;0;0;2;0;0 92575;238808;SCALUS;ONG;FP7-PEOPLE;FP7-PEOPLE-ITN-2008;FP7;SCALing by means of Ubiquitous Storage;2009-12-01;2013-11-30;;Storage research increasingly gains importance based on the tremendous need for storage capacity and I/O performance. Over the past years, several trends have considerably changed the design of storage systems, starting from new storage media over the widespread use of storage area networks, up to grid and cloud storage concepts. Furthermore, to achieve cost efficiency, storage systems are increasingly assembled from commodity components. Thus, we are in the middle of an evolution towards a new storage architecture made of many decentralized commodity components with increased processing and communication capabilities, which requires the introduction of new concepts to benefit from the resulting architectural opportunities. The consortium of this Marie Curie Initial Training Network (MCITN) „SCALing by means of Ubiquitous Storage (SCALUS)“ aims at elevating education, research, and development inside this exciting area with a focus on cluster, grid, and cloud storage. The vision of this MCITN is to deliver the foundation for ubiquitous storage systems, which can be scaled in arbitrary directions (capacity, performance, distance, security) Providing ubiquitous storage will become a major demand for future IT systems and leadership in this area can have significant impact on European competitiveness in IT technology. To get this leadership, it is necessary to invest into storage education and research and to bridge the current gap between local storage, cluster storage, grid storage, and cloud storage. The consortium will proceed into the direction by building the first interdisciplinary teaching and research network on storage issues. It consists of top European institutes and companies in storage and cluster technology, building a demanding but rewarding interdisciplinary environment for young researchers.;3298114;3298114;FP7-PEOPLE-ITN-2008;/MC-ITN;UNIVERSITAET PADERBORN;DE;"INSTITUT NATIONAL DE RECHERCHE ENINFORMATIQUE ET AUTOMATIQUE;FUJITSU TECHNOLOGY SOLUTIONS GMBH;XLAB RAZVOJ PROGRAMSKE OPREME IN SVETOVANJE DOO;UNIVERSITAET HAMBURG;SEAGATE SYSTEMS UK LIMITED;UNIVERSITY OF DURHAM;FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS;ASSOCIATION POUR LA RECHERCHE ET LE DEVELOPPEMENT DES METHODES ET PROCESSUS INDUSTRIELS;JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN;UNIVERSIDAD POLITECNICA DE MADRID;BARCELONA SUPERCOMPUTING CENTER - CENTRO NACIONAL DE SUPERCOMPUTACION";"FR;DE;SI;UK;EL;ES";"/SCI;/EDU";1;0;0;2;0;0 105589;300616;INTERSECTINGCONTRACT;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IEF;FP7;Intersectional Contract. Understanding the Intersection of Gender and “Race”/Ethnic Inequalities in the Care-Domestic Sector in the UK by Means of Racial-Sexual Contract Analysis;2013-10-01;2015-11-12;;The 2007 EC Report “Tackling Multiple Discrimination” addressed for the first time at the EU level the issue of intersectionality, an approach that seeks to understand several forms of discrimination (based on gender, “race”/ethnicity, class and so forth) as the results of intersecting biases rather than of single sources of inequality. This represents a significant step towards increasing awareness of the interrelation of different types of discrimination, enabling policy makers to tackle it in a more effective manner. This research project, using an interdisciplinary approach that combines intersectionality theory and “racial-sexual contract” analysis, aims to contribute to this debate by focusing on gender and “race”/ethnicity biases in the care-domestic labour sector in the UK. It is of the greatest importance to consider the combined impact of gender and “racial”/ethnic factors on a labour market that has witnessed dramatic growth in the participation of women of ethnic minority background across all EU Member States in recent years. The study of the care-domestic sector in the UK is of particular interest due to the more advanced and articulated character of this phenomenon in the UK, and the responses it has elicited on both the policy and theoretical level. The research project introduces the new concept of “intersectional contract” and operationalizes it for empirical research. A mixed-method approach is employed, including the gathering of quantitative data, qualitative in-depth interviews with key actors (domestic placement agencies’ owners, employers, employees and policy makers), and critical discourse analysis of regulations and policy documents. This research project will consolidate the researcher’s profile as an expert sociologist of gender and migration, enable the acquisition of new competencies and interdisciplinary skills and position the researcher as a leading scholar of themes of current dramatic socio-economic relevance.;209033,4;209033,4;FP7-PEOPLE-2011-IEF;/MC-IEF;GOLDSMITHS' COLLEGE;UK;THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;UK;/SCI;1;0;0;2;0;0 92273;237907;ITN-LCG;ONG;FP7-PEOPLE;FP7-PEOPLE-ITN-2008;FP7;Language, Cognition, and Gender;2009-10-01;2013-09-30;;The Initial Training Network - Language, Cognition, and Gender (ITN LCG) investigates European languages from an interdisciplinary perspective to expand current knowledge of how language influences and forms the cognitive representations of women and men. The diversity of Europe offers a unique opportunity to investigate the impact of language and culture in establishing and maintaining gender inequality. This issue has not yet been systematically addressed on a large scale, although the reduction of gender inequality is generally considered an important issue within Europe. Therefore, ITN LCG will provide a structured interdisciplinary research training programme for young researchers in the emerging supra-disciplinary field of language, cognition, and gender to enhance the scientific understanding of this topic and improve the quality of initial research training in Europe. For the first time, these lines of research will be investigated from cross-language and cross-cultural perspectives by bringing together 10 complementary providers of research-training and 12 associated partners from public and private sectors. ITN LCG has four interrelated research objectives: a) deriving indices for selected European languages that reflect the extent to which the features of a language result in gender related representations in speakers/listeners, b) investigating to what extent gender equality in formal standards of language and the use of gender-fair language correlates with higher levels of socio-economic gender equality, c) analysing the impact of language on gender stereotyping in social judgement and decision making, and d) developing and evaluating scientifically-based prototypes of guidelines and training tools for gender-fair communication in European languages. ITN LCG will strengthen the capability of its young fellows to contribute effectively to our knowledge-based economy and society, and will add to their intersectoral and transnational employability.;4106379;4106379;FP7-PEOPLE-ITN-2008;/MC-ITN;UNIVERSITAET BERN;CH;"BCBL BASQUE CENTER ON COGNITION BRAIN AND LANGUAGE;JIHOCESKA UNIVERZITA V CESKYCH BUDEJOVICICH;RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG;UNIVERSITAET DUISBURG-ESSEN;UNIVERSITA DEGLI STUDI DI PADOVA;THE UNIVERSITY OF SUSSEX;FREIE UNIVERSITAET BERLIN;UNIVERSITE DE FRIBOURG;UNIVERSITA DEGLI STUDI DI MODENA E REGGIO EMILIA;NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU";"ES;CZ;DE;IT;UK;CH;NO";"/SCI;/EDU";1;0;0;2;0;0 93504;238438;INCOOP;ONG;FP7-PEOPLE;FP7-PEOPLE-ITN-2008;FP7;DYNAMICS OF INSTITUTIONAL COOPERATION IN THE EUROPEAN UNION;2010-01-01;2014-05-31;;"This ITN brings together Universities, think-tanks and high-level officials that all share a long-term interest in a better understanding of the functioning of institutions in the European system of Multi-level governance (MLG) and who have extensive academic and practical expertise in this field. Their interdisciplinary knowledge and experience is pooled with the main objective of improving the European career opportunities of young researchers by offering them a coherent academic training programme complemented with a professional skills training programme and by exposing them to experience on the work-floor through an internship at a think-tank or consultancy. The research focus is the rapidly-evolving field of European inter-institutional cooperation. The comprehensive study of cooperative forms of decision- and policymaking is of interest in the light of the current political and academic debate on institutional reform. Moreover it also contributes to our broader understanding of the origins, evolution and effects of institutions. Training ojectives: To instil researchers with a sound knowledge of quantitative and qualitative Research Methods and to get them acquaint to interdisciplinary research; To provide researchers with insights into Theories and Concepts of institutional cooperation; To equip young researchers with practical Skills that prepare them for the job market. Research objectives: To develop and arrive at theory-based explanations of the impact of institutional cooperation on policy-making in the widest sense; To collect a rich pool of empirical data and produce comparative evidence on conditions for and effects of cooperative governance in the EU; To derive comprehensive and comparative explanations of cooperation by adopting an inter-disciplinary approach.";3093003;3093003;FP7-PEOPLE-ITN-2008;/MC-ITN;UNIVERSITEIT MAASTRICHT;NL;"THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;FONDATION NATIONALE DES SCIENCES POLITIQUES;UNIVERSITAET MANNHEIM;UNIVERSITE DU LUXEMBOURG;ACADEMIA DE STUDII ECONOMICE DIN BUCURESTI;LOUGHBOROUGH UNIVERSITY;UNIVERSITAET OSNABRUECK";"UK;FR;DE;LU;RO";"/SCI;/EDU";1;0;0;2;0;0 92722;240750;ARCHGLASS;ONG;FP7-IDEAS-ERC;ERC-SG-ID1;FP7;Archaeometry and Archaeology of Ancient Glass Production as a Source for Ancient Technology and Trade of Raw Materials;2009-11-01;2014-10-31;;In this project, innovative techniques to reconstruct ancient economies are developed and new insights in the trade and processing of mineral raw materials are gained based on interdisciplinary archaeological and archaeometrical research. An innovative methodology for and a practical provenance database of the primary origin of natron glass from the Hellenistic-Roman world will be established. The project investigates both production and consumer sites of glass raw materials using both typo-chronological and archaeometrical (isotope geochemical) study of finished glass artefacts at consumer sites as well as mineralogical and chemical characterisation of raw glass and mineral resources at primary production sites. Suitable sand resources in the locations described by ancient authors will be identified through geological prospecting on the basis of literature review and field work. Sand and flux (natron) deposits will be mineralogically and geochemically characterised and compared to the results of the archaeological and geochemical investigations of the glass. Through integrated typo-chronological and archaeometrical analysis, the possible occurrence of primary production centres of raw glass outside the known locations in Syro-Palestine and Egypt, particularly in North-Africa, Italy, Spain and Gaul will be critically studied. In this way, historical, archaeological and archaeometrical data are combined, developing new interdisciplinary techniques for innovative archaeological interpretation of glass trade in the Hellenistic-Roman world.;954960;954960;ERC-2009-StG;/ERC-SG;KATHOLIEKE UNIVERSITEIT LEUVEN;BE;;;/SCI;1;0;0;2;0;0 97197;262348;ESMI;ONG;FP7-INFRASTRUCTURES;INFRA-2010-1.1.30;FP7;European Soft Matter Infrastructure;2011-01-01;2015-12-31;;"The central objective of this ESMI proposal is to create a top-level interdisciplinary research infrastructure available to a broad European materials research community. This is of crucial importance to the EU in view of the European strategy for nanosciences and nanotechnology and its implementation report that identifies “a lack of leading interdisciplinary infrastructures”. ESMI offers the most important experimental and synthesis techniques and combines world-class infrastructures with cutting edge scientific expertise through a sophisticated networking programme. The anticipated JRA will further improve the existing infrastructure. Computer simulations being of increasing importance for the understanding and prediction of complex materials, ESMI offers access to simulation groups and their advanced tools. The availability of such an infrastructure will provide soft matter scientists with a broad choice of techniques to address their scientific objectives. It will result in a quantum leap in research opportunities and assure that European scientists have a world-class collaborative capability for their frontier research. ESMI will strongly contribute to a fundamental understanding, allowing the development of new, tailored smart materials. ESMI follows the FP6 experience of the NoE SoftComp. A key feature developed within SoftComp is the highly successful Research Platforms offered to its members, anticipating the spirit of the EU Integrated Infrastructure Initiative. ESMI will promote the SoftComp experience to the European materials community, reflecting the EU recommendations that FP6 collaborative projects “may well lead to new European infrastructures”. Together with a platform for disseminating the results and educating a new generation of young soft matter scientists, ESMI represents an important added value to the European Research Area in nanoscience, nanotechnology and materials science";9702154,71;7800000;FP7-INFRASTRUCTURES-2010-1;/CP-CSA-Infra;FORSCHUNGSZENTRUM JULICH GMBH;DE;"ASOCIACION CENTRO DE INVESTIGACION COOPERATIVA EN BIOMATERIALES- CIC biomaGUNE;UNIVERSITEIT ANTWERPEN;BIOLIN SCIENTIFIC OY;UNIVERSITAET HAMBURG;UNIWERSYTET IM. ADAMA MICKIEWICZA W POZNANIU;VISITECH INTERNATIONAL LIMITED;UNIVERSITEIT TWENTE;FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS;UNIVERSITY OF LEEDS;MALVERN INSTRUMENTS LTD;PAUL SCHERRER INSTITUT;LUNDS UNIVERSITET;KATHOLIEKE UNIVERSITEIT LEUVEN;LS INSTRUMENTS AG;UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA;THE UNIVERSITY OF EDINBURGH;UNIVERSIDAD DE VIGO";"ES;BE;FI;DE;PL;UK;NL;EL;CH;SE";/SCI;1;0;0;2;0;0 192250;607290;SPARTAN;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-ITN;FP7;Sparse Representations and Compressed Sensing Training Network;2014-10-01;2018-09-30;;The aim of this Initial Training Network is to train a new generation of interdisciplinary researchers in sparse representations and compressed sensing, contributing to Europe’s leading role in scientific innovation. By bringing together leading academic and industry groups with expertise in sparse representations, compressed sensing, machine learning and optimization, and with an interest in applications such as hyperspectral imaging, audio signal processing and video analytics, this project will create an interdisciplinary, trans-national and inter-sectorial training network to enhance mobility and training of researchers in this area.;2812782,73;2812782,73;FP7-PEOPLE-2013-ITN;/MC-ITN;UNIVERSITY OF SURREY;UK;"INSTITUT NATIONAL DE RECHERCHE ENINFORMATIQUE ET AUTOMATIQUE;Instituto de Telecomunicaç?es;NOISELESS IMAGING OY;ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE;VISIOSAFE SA;THE UNIVERSITY OF EDINBURGH";"FR;PT;FI;CH;UK";/LIF;1;0;0;2;0;0 108318;328530;EUENDOLIGHT;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IOF;FP7;Mineral excavation by photosynthetic microbes, a geochemical survey of a biological paradox;2013-09-16;2017-01-05;;"This interdisciplinary proposal aims to make important contributions in the field of microbes-mineral interactions using as model system the boring process of endolithic cyanobacteria. Cyanobacteria are photosynthetic bacteria which count among the most common, widespread and environmentally significant agents of bio-erosion, boring microscopic galleries as they grow within carbonate substrates. The mechanisms by which they achieve this against chemical equilibrium are poorly known. This project objective is to better understand mechanisms involved in cyanobacteria boring activity, detail, its phylogenetic distribution and to characterize the mineral and geochemical signatures of this process, so as to be able to apply it in the interpretation of paleobiological records. This will be achieved by studying laboratory cultures of cyanobacteria, performing boring assays in various substrates, and monitoring the boring activity. Diverse tools from molecular biology, microbiology and geochemistry will be used including confocal laser scanning microscopy, electron microscopy and secondary ion mass spectroscopy. That all together will allow in-situ survey of intracellular and extracellular chemistry variations, the identification of molecular bases of the process as well as the nature and distribution of mineral phases and organic. This will help to refine microbial and mineralogical models for the mechanisms involved, and to assess the quantitative importance of boring cyanobacteria in present and past ecosystem. My goal with this proposal is to establish a truly interdisciplinary expertise in the study of endolithic cyanobacteria by joining the skills and tools of the Garcia-Pichel lab (ASU-USA) and Biogéosciences lab (uB-France). This project will be a unique opportunity to become an accomplished researcher in geomicrobiology able to collaborate with people from both research fields and to apply this unique dual toolbox to the development of my own project in the future.";268781,1;268781,1;FP7-PEOPLE-2012-IOF;/MC-IOF;UNIVERSITE DIJON BOURGOGNE;FR;;;/LIF;1;0;0;2;0;0 90416;230113;MDCEE;ONG;FP7-IDEAS-ERC;ERC-AG-ID1;FP7;Media and Democracy in Central and Eastern Europe: Qualities of Democracy, Qualities of Media;2009-10-01;2013-09-30;;The relationship between democracy and the media in Central and Eastern Europe (CEE) is poorly understood. Not only have western media models been unhelpful in understanding these transitions but there has also been a notable lack of attention given to media within the transitions literature. This project intends to address this by taking a novel and interdisciplinary approach to this question. The traditional orientation of academic studies to this question is strictly limited to whether media are good or bad for democracy. This rests on the assumptions that both democratic institutions have pre-dated the rise of media and that core qualities of democratic governance exist (i.e. rule of law, political pluralism, freedom of speech and information, etc.). Unfortunately for the countries of CEE, these are problematic assumptions to make. Thus, this project asks: What kind of democracy is needed for media to perform its agreed-upon normative functions? That is, we are interested in the quality of the media as a function of the quality of democracy. The principal investigators are leading academic authorities in the field of European Politics and of Media and Communications. They have expertise in the study of Eastern Europe and experience in managing large interdisciplinary research projects. The Department of Politics and International Relations at the University of Oxford, its Reuters Institute for the Study of Journalism and the Department of Media and Communications at the London School of Economics offer a unique academic and journalistic environment of the highest possible quality for this proposed study. The expected results and outputs will not only help us to understand democracy and the media in the new member states of the European Union but will also be more broadly applicable to the study of the relationship between democracy and the media in other consolidating democracies, including the Balkans, Latin America, Asia, the Middle East, and Africa.;2056276;2056276;ERC-2008-AdG;/ERC-AG;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;UK;LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE;UK;/SCI;1;0;0;2;0;0 92783;227845;MASC;ONG;FP7-IDEAS-ERC;ERC-AG-ID1;FP7;MASC: Materials that Impose Architecture within Stem Cell Populations;2010-01-01;2014-12-31;;This proposal aims to harness breakthroughs in polymer science, nanotechnology and materials processing to create new classes of materials that mimic the architecture of the human body. The materials will be exploited to tackle grand challenges in stem cell science and in the development of new biomaterials that promote regeneration. The human body uses materials to impose architecture on populations of cells within developing or regenerating tissues. Architectural components of these tissues include three-dimensional spatial and temporal patterns of growth factors, spatial arrangements of multiple cell types and modulation of local elasticity. Orchestration of these architectural features is essential in the precise control of stem cell differentiation and tissue morphogenesis in vivo. This ERC Grant will create new classes of biomaterials that bridge the gap between the exquisite control of architecture in the developing human body and the crude structure imposed on cell populations in vitro during cell culture and biomaterials-assisted tissue repair. The research programme is organised into 2 major strands: TOOLS and DEMONSTRATORS. Within TOOLS, new materials and techniques will be invented that represent a step-change in our ability to impose architecture on stem cell populations in vitro. Within DEMONSTRATORS, 3 grand challenges in healthcare and stem cell science will be addressed through demonstrations that synthetic materials can be designed to match the architecture of our developing bodies. This interdisciplinary project will be undertaken by a team of interdisciplinary scientists within the Wolfson Centre for Stem Cells Tissue Engineering and Modelling (STEM). To undertake this research project help from collaborators across Europe is required. Existing and new collaborations will ensure that the most advanced materials science and stem cell biology is exploited to create world leading tools that radically change regenerative medicine.;2290856,8;2290856,8;ERC-2008-AdG;/ERC-AG;THE UNIVERSITY OF NOTTINGHAM;UK;;;/SCI;1;0;0;2;0;0 99374;273992;FUNALGPDE;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-IOF;FP7;Functorial and algebraic methods in the study of systems of linear partial differential equations;2011-10-01;2013-09-30;;"'A first aim of the research project FUNALGPDE is to let the applicant get in a long contact with the Research Institute for Mathematical Sciences, Kyoto, Japan. At RIMS Dr Morando will learn new interdisciplinary methods in the algebraic study of differential equations and their applications to other fields of mathematics (representation theory, differential geometry, Hodge theory, algebraic geometry and mirror symmetry) from many internationally acknowledged mathematicians. In a second period, the project aims to reintegrate Dr Morando in the European scientific community letting him to develop his research in Europe. Moreover, the Universit? degli Studi di Padova will benefit of all the knowledge Dr Morando would have acquired in Japan. In particular, Dr Morando will be able to connect different research groups at the Universit? di Padova coming from algebra, geometry, analysis and physics. These groups seems to be heterogeneous and slightly related at a first sight but recent advances in mirror symmetry, algebraic geometry and differential equations have deepened the interconnections between them, linking very different problems and methods in mathematics and physics. Such recent techniques and results have been developed mainly in Japan and by mathematicians of the RIMS. Dr Morando is the perfect candidate for this project. He developed very good abilities in the processes of learning, teaching and cooperating in many different countries. He already established very good cooperations with Japanese or other foreign researchers which led to important scientific achievements. He will be able to pass the acquired knowledge to various research groups inside the Universit? di Padova even of different scientific nature. This project allows Dr Morando to highly increase his value inside the Universit? di Padova and the international scientific world in general as an expert in new interdisciplinary methods and areas at the forefront of the scientific research.'";160592;160592;FP7-PEOPLE-2010-IOF;/MC-IOF;UNIVERSITA DEGLI STUDI DI PADOVA;IT;;;"/EMP;/SOC;/COO";1;0;0;2;0;0 105413;317297;GLYCOPHARM;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-ITN;FP7;The Sugar Code: from (bio)chemical concept to clinics;2012-11-01;2016-10-31;http://www.glycopharm.eu/;Coding of biochemical information is commonly described to be based solely on nucleotides and amino acids, whereas carbohydrates, the most abundant type of molecule in Nature, appear sidelined in this respect. That carbohydrates, as part of cellular glycoconjugates, have exceptional talents for building biochemical signals is an emerging insight, at the heart of the concept of the Sugar Code. Intuitively, emergence of recognition partners for information transfer is expected, and this is the case. Thus, coding of bioinformation in glycans and information transfer via lectins is key to a wealth of medically relevant processes, e.g. infection, immune regulation and malignancy, now awaiting its full exploitation pharmaceutically. To do so, training in this exceptionally interdisciplinary field needs to be provided. With this aim, scientific and country/gender issues are strategically combined in this network. Its composition assures a continuous chain of research expertise, from computational and synthetic chemistry to state of the art biophysical chemistry and structural biology, then to biochemistry, molecular cell biology and pharmaceutical/biomedical sciences, generating innovative clinical approaches. Notably, academia is linked with industry, bringing in the essence of business acumen into the training programme. This activity and the research deliberately planned as interdisciplinary projects ensure an optimal training for young researchers in a dynamically developing area of conspicuous biopharmaceutical potential. Equally important, it lays the foundation to inspire novel strategies for the design of potent and selective inhibitors against lectins and the development of lectins (or suitably engineered variant(s)) as therapeuticals. As a boon for the success of the network, cooperations between several partners have already proven successful, especially increasing the core in Madrid and partners in Dublin, Munich and Prague.;3005458,3;3005458,3;FP7-PEOPLE-2012-ITN;/MC-ITN;AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS;ES;"UNIVERSIDADE DO MINHO;LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN;UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN;INSTITUTE OF APPLIED BIOTECHNOLOGIES AS;ROCHE DIAGNOSTICS GMBH;FUNDACION UNIVERSITARIA SAN PABLO-CEU;UNIVERSITAETSKLINIKUM HEIDELBERG;UNIVERZITA KARLOVA;TOSCANA BIOMARKERS S.R.L;ISOSEP AKTIEBOLAG";"PT;DE;IE;CZ;ES;IT;SE";/LIF;1;0;0;2;0;0 98009;263760;FAMMAT;ONG;FP7-IDEAS-ERC;ERC-SG-SH3;FP7;Family Matters: Intergenerational Influences on Fertility;2011-03-01;2015-08-31;;Why do people have children? Why do they have the number of children they do? These questions are of fundamental importance, but we do not yet have satisfactory answers. I propose to bring an interdisciplinary perspective, involving demography, evolutionary biology, anthropology and psychology, to bear on this topic. The aim is to test the hypothesis that intergenerational influences are important determinants of fertility, from fertility intentions to timing of births to number of children. The theoretical rationale derives from a hypothesis emerging from evolutionary biology that humans are cooperative breeders : mothers need help from others to raise children, because human children are too costly for mothers to raise alone. The support of relatives, particularly intergenerational support, is thus vital to women in determining how many children they have. If so, there is a major gap in our understanding of fertility, since such influences have not been systematically studied. This aim will be achieved using rigorous, empirical methods to analyse data from all world regions, and to use novel methods for collecting new data on fertility. The key to this project is its holistic comparative nature. The ultimate goal will be a novel comparative analysis of data from the full gamut of human societies, from small-scale traditional societies through historical populations to contemporary nations surveyed through large-scale surveys. This will allow us to go beyond simply documenting kin influences, and to understand why particular kin matter under which circumstances. Such a comparative approach has not been used before but is vital if we are to fully understand why fertility varies. This will significantly advance understanding of fertility, and promote interdisciplinary research.;799998;799998;ERC-2010-StG_20091209;/ERC-SG;LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE;UK;UNIVERSITY OF DURHAM;UK;/SOC;1;0;0;2;0;0 103856;300828;CrossLingMind;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IEF;FP7;Automated analysis of opinions in a multilingual context;2012-10-01;2014-09-30;;"In the recent years, massive amounts of personal opinions have been posted on the Internet. This allows the companies and institutions to get feedback about their services, provided that they are able to analyse this mass of information.Given that most people prefer to write and read information in their own language, it is clearly relevant to be able to analyse in one language opinions expressed in another language. This is an interdisciplinary topic, called cross-lingual opinion analysis, which involves opinion analysis and machine translation. Although both topics involved have reached a high maturity level, cross-lingual opinion analysis has been little explored. Most of the work done in this field aimed at leveraging resources in English to perform monolingual opinion analysis in another language. The objective of this project is to develop a cross-lingual opinion analysis system. To achieve this goal, the fellow will apply his knowledge in machine translation to adapt the monolingual opinion analysis system existing at the host institution. The fellow will develop a novel approach to map across languages concepts such as the opinion target entity, the corresponding attribute and its polarity. This approach consists of enriching the machine translation system with relevant contextual information. Furthermore several possible architectures of the system will be evaluated and finally a demonstrator will be developed. The underlying technology will eventually be transferred to the industrial sector, since this is one of the missions of the host institution. Thus the fellow will gain interdisciplinary and inter-sectoral competences. In addition, European companies will be able to improve their competitiveness. The citizens will be the final beneficiary since companies and public institutions will be able to better take their opinions into account.";233705,2;233705,2;FP7-PEOPLE-2011-IEF;/MC-IEF;UNIVERSIDAD POMPEU FABRA;ES;FUNDACIO BARCELONA MEDIA;ES;/SCI;1;0;0;2;0;0 94345;249982;FORCEFULACTIN;ONG;FP7-IDEAS-ERC;ERC-AG-ID1;FP7;Coordinated regulation of actin dynamics in cell motility and morphogenesis : from molecules to reconstituted biomimetic assays;2010-05-01;2015-10-31;;An impressive variety of motile and morphogenetic processes are driven by site-directed polarized asssembly of actin filaments. In the past ten years, breathtaking advances coming from cell biology, cell biophysics, and biochemistry have brought insight into the molecular bases for production of force and movement by site-directed actin polymerization. Yet, we do not know, with the detail sufficient to understand how force is produced, by which molecular mechanisms the filaments are nucleated or created by branching. We do not know by which elementary steps insertional polymerization of barbed ends of filaments against the membrane is performed by different protein machineries, nor how these machineries work in a coordinated fashion. Here we propose a multiscale and interdisciplinary approach of the mechanisms used by the major actin nucleators to organize the motile response of actin. The elementary reactions involved in the processive walk of formin at the growing barbed ends of filaments and the role of ATP hydrolysis in force production will be analyzed by a combination of biochemical solution studies and physical methods using functionalized GUVs and optical tweezers. The multifunctionality of WH2 domains involved in actin sequestration, filament nucleation severing and processive elongation will be similarly examined in an interdisciplinary perspective from structural biology at atomic resolution to physics at the mesoscopic scale. Biochemical and structural methods and single molecule measurements (TIRFM) will shed light into the elementary steps and structural mechanism of filament branching. Biomimetic assays with functionalized GUVs associated with biophysical methods like FRAP or fluorescence correlation spectroscopy will elucidate how different filament initiating machineries segregate in the membrane as a consequence of their interactions with growing filaments and function in a coordinated fashion during actin-based motility.;2434195;2434195;ERC-2009-AdG;/ERC-AG;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FR;"TECHNISCHE UNIVERSITAET BRAUNSCHWEIG;RHEINISCHE FRIEDRICH-WILHELMS-UNIVERSITAT BONN";DE;/SCI;1;0;0;2;0;0 97078;264719;PUREFOOD;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-ITN;FP7;Urban, peri-urban and regional food dynamics: toward an integrated and territorial approach to food;2010-12-01;2014-11-30;;"Increasing urban food-related health and environmental problems are raising an urgent need for action. Current agrifood studies tend to neglect the broader societal and spatial impacts of food. PUREFOOD will reduce the high knowledge and skills deficit that negatively affects the capacity to deliver political and developmental solutions related to food security, public procurement, health and sustainable regional development. Through its innovative methodology, the interdisciplinary courses, private and public sector involvement, the holistic conceptualization of sustainable food and the formation of Communities of Practice (CoPs) that include actors at all stages of the food chain, PUREFOOD contributes to Commission’s aim to deal with economic, social and environmental policies in mutually reinforcing ways. We study an alternative geography of food, based upon three emerging trends; sustainable food supply chains, public sector food procurement practices and (peri-)urban food strategies. Each is topic of a scientific WP with 4 ESRs in individual research projects using case study methodology. The related training aims to transfer disciplinary scientific knowledge and skills between complementary groups, leading to a coherent frame of basic and advanced scientific, professional and host institute training modules, and to interactively develop scientific and professional knowledge and skills through ‘learning-by-doing’ in CoPs for each WP. PUREFOOD consists of 7 full academic partners and 8 associated partners (private sector and socio-economic partners). PUREFOOD’s coordinator has ample experience in managing international interdisciplinary research and training projects. The commitment of private and public organisations and NGOs as associated partners illustrate the timeliness of our proposal and impact to the career perspectives of the ESRs. Completed CDPs give access to a PhD degree at every partner university.";2886380;2886380;FP7-PEOPLE-2010-ITN;/MC-ITN;WAGENINGEN UNIVERSITY;NL;"MAKERERE UNIVERSITY;UNIVERSITA DI PISA;CITY UNIVERSITY OF LONDON;UNIVERSIDADE FEDERAL DO RIO GRANDE DO SUL;LATVIJAS UNIVERSITATE;CARDIFF UNIVERSITY";"UG;IT;UK;BR;LV";"/EDU;/NET";1;0;0;2;0;0 104678;299195;IceDISC;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IEF;FP7;Ice Dynamic Investigations with Seismological Components;2012-10-01;2014-09-30;;"Glacier ice mass loss presently contributes 1.8 mm per year to global sea level rise. The cause of this loss can be divided into two primary categories: negative surface mass balance and increases in ice discharge into the ocean. The latter is also known as dynamic mass loss. Predicting global sea level changes is primarily limited by gaps in our understanding of glacier sliding and iceberg calving inhibiting the inclusion of dynamic mass loss in ice sheet models. The main issue is the inaccessibility of a glacier’s base and its calving front, which significantly limits the amount of conclusive data on physical processes in these regions. To get around this problem, I propose to implement an interdisciplinary approach that investigates glacier sliding and iceberg calving using new seismological techniques. The main component focuses on the linkages between changes in glacier surface melt and basal sliding, by investigating the subglacial drainage system with a seismic noise analysis technique. In the second part of this study, I propose to analyze regional seismograms and satellite images to develop and refine quantitative monitoring tools of iceberg calving. The Institute des Sciences de la Terre (ISTerre) at the University Joseph Fourier in Grenoble will serve as a host institution, contributing their extensive experiences and resources in the field of seismic noise analysis. For the first time, such an analysis will be applied to glacier seismograms, which will extend my scientific skill set in interdisciplinary research of glacier seismology. As an integral part of ISTerre's scientific community, I will have the opportunity to extend my professional network, continue to supervise students and dovetail my previously developed outreach activities into the institute's programs. Overall, this project will help me flourish in my career as an independent researcher with a strong record of international mobility.";193594,8;193594,8;FP7-PEOPLE-2011-IEF;/MC-IEF;UNIVERSITE JOSEPH FOURIER GRENOBLE 1;FR;;;/SCI;1;0;0;2;0;0 92348;237890;INTRAMIF;ONG;FP7-PEOPLE;FP7-PEOPLE-ITN-2008;FP7;INitial TRAining network on Mass Independent Fractionation;2009-09-01;2013-08-31;;Molecules containing the element oxygen can be further characterized by the distributions of the stable oxygen isotopes. In some cases, these isotopes have an anomalous distribution, which is evidence of Mass Independent Fractionation (MIF). MIF has become a powerful research tool in earth system science and its use is expected to spread from the core science disciplines to industrial applications. With INTRAMIF, we bring together experts from atmospheric and climate research, hydrology, oceanography and molecular physics. 13 ESR projects from these disciplines are connected by the common theme of MIF. Sharing expertise and world-class facilities will allow the individual groups to do research that would otherwise be impossible. This will create a center of excellence for MIF research in Europe. The associated industrial partners of INTRAMIF will integrate the research and training programs with ‘real-world’ opportunities, including commercialization of new techniques and the application of MIF to solve questions on water supplies and food authentication. The broad scientific program allows us to combine specialized training at the host institutions with a unique interdisciplinary and intra-sector network training program on the climate system involving associated partners from the industrial, political and economic sectors. The strong interest from our associated partners documents the need for highly qualified scientists with a wide interdisciplinary background. INTRAMIF will educate the next generation of scientists that can tackle new challenges to society in a changing climate.;3036392;3036392;FP7-PEOPLE-ITN-2008;/MC-ITN;UNIVERSITEIT UTRECHT;NL;"UNIVERSITY OF EAST ANGLIA;COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES;UNIVERSITAET BERN;KOBENHAVNS UNIVERSITET;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS";"UK;FR;CH;DK";"/SCI;/EDU";1;0;0;2;0;0 109629;618522;LIFESPAN DMC;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-CIG;FP7;Improving decision-making competence and associated quality of life across the lifespan;2013-09-01;2017-08-31;;"Across the life span, people face decisions about their health, finances and well-being. People of all ages therefore need good decision-making competence, referring to the ability to avoid decision biases and to obtain desired life outcomes. Reviews suggest that relatively little is known about how decision-making competence changes with age. However, well-documented aging-related declines in fluid cognitive abilities such as working memory start around age 20, threatening the quality of older adults’ decisions and associated quality of life. Because population age is increasing in the EU and the US, the European Commission sees maintaining older adults’ quality of life as a main policy challenge, and aims for Europe to be a leader in innovative strategies for improving quality of life across the lifespan. To address these pressing concerns, the 3 objectives of the planned research are: (1) Understanding the relationship between aging and decision-making competence across decision tasks, using validated measures of individual differences with EU samples; (2) Applying interdisciplinary insights from lifespan developmental theories to identify non-cognitive skills that facilitate better decision-making competence across the lifespan; (3) Designing and evaluating programs to build those skills that promote decision-making competence across the lifespan. The proposed work will build on new interdisciplinary insights from lifespan developmental theories and behavioral decision research, benefiting from the research program of Professor Bruine de Bruin (the applicant) who recently moved from the University of Leeds (UK) after 10 years at Carnegie Mellon University (US). Requested funds will help to move her research program to the EU, train affiliated junior EU colleagues, raise the team’s EU profile, and inform EU policy on aging. Findings will inform theories of decision making and aging, while promoting better decision making across the adult lifespan.";100000;100000;FP7-PEOPLE-2013-CIG;/MC-CIG;UNIVERSITY OF LEEDS;UK;;;/LIF;1;0;0;2;0;0 92964;228821;QUARISMA;ONG;FP7-PEOPLE;FP7-PEOPLE-IAPP-2008;FP7;Quality and Risk Management in Meat Chains;2009-09-01;2013-08-31;;The EU meat industry is in the process of adapting itself more strongly than previously to the demands and needs for quality products. From the scientific view there are three parallel innovation challenges: 1. the chain inversion, that means the transition from a supply to a demand driven supply chain and self-regulation, 2. the support of new sustainable technologies in food safety control systems, 3. the establishment of a knowledge infrastructure for the development and implementation of technologies and new structures as an integral part of the transition. QUARISMAs goal is to stimulate more sustainable development in the European meat sector, and simultaneous, to mobilise the scientific knowledge needed to bring this about. This will be achieved mainly by collaborating in interdisciplinary cross-boarder research teams to develop a new knowledge infrastructure to translate knowledge questions from practice projects into research questions and vice versa. Collaborations between two universities and two private organisations in the meat sector supported by a public-private-partnership organisation will be established to come to grips with this complex of problems. The join intersectoral program will synthesize and place into perspective the seemingly wide divergent topics of Chain Management, Quality and Information Management, as well as Food Safety and Risk Management into a cohesive focus to maintain the highest food safety and quality for the consumers benefit. The transfer of knowledge will be further enhanced by the research fellowships of staff members and researchers in five partner institutions from Germany and the Netherlands. This novel interdisciplinary research team will lead this proposal to achieve scientific as well as social goals and will potentially set new trends to establish European research in quality and risk management as having a world-leading role in this field with reference of the meat sector.;2435063;2435063;FP7-PEOPLE-IAPP-2008;/MC-IAPP;Grenzüberschreitende integrierte Qualitätssicherung e.V.;DE;"AGRI-Q SERVICE GMBH;ERSEUGERGEMEINSCHAFT SUDOSTBAYERN EG;DEUTSCHER RAIFFEISENVERBAND EV;RHEINISCHE FRIEDRICH-WILHELMS-UNIVERSITAT BONN;VION Fresh Meat North GmbH;WAGENINGEN UNIVERSITY;ERZEUGERGEMEINSCHAFT FÜR SCHLACHTVIEH IM RAUM OSNABRÜCK EG;GEZONDHEIDSDIENST VOOR DIEREN BV";"DE;NL";/EDU;1;0;0;2;0;0 109775;618558;VisualTransport;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-CIG;FP7;Visualizing Functional Structural Dynamics of Membrane Protein Transporters;2013-09-01;2017-08-31;;Membrane protein transporters catalyze fundamental physiological processes in all kingdoms of life. A schematic view of membrane transport is emerging from a growing number of crystal structures. However, several fundamental features of membrane protein transport are still evasive, such as how the protein transition between states, what triggers these structural rearrangements, and how the release of energy is coupled to the transport event. The proposed research will build an interdisciplinary platform, which uses molecular biology, biophysical and computational techniques, to characterize membrane protein transport over the full spatio-temporal scale. Molecular dynamics (MD) simulations will capture high-resolution dynamics on the nano-to-microsecond timescale, which will identify communicative salt-bridge/H-bond networks, putative transport pathways, and the energetics involved in substrate transport. Predictions from the simulations will be verified by in vitro characterization of mutagenic phenotypes. Time-resolved wide-angle X-ray scattering (TR-WAXS) will monitor the micro-to-millisecond, large-scale structural rearrangements, which are out of reach for the MD simulations. The proposed platform for characterization of membrane protein transporters will be developed using a copper-transporting P-type ATPase (CopA) as the initial model system. The P-type ATPase family is divided into types I-V, depending on the transported substrate. CopA is the first crystal structure from the type-I ATPases, making it a particularly exciting model system. The applicants’ preliminary molecular dynamics (MD) simulations and the CopA transmembrane architecture strongly indicate a unique mode of transport in type-I ATPases. Hence, by means of visualization of copper transport, this proposal enables the development of an interdisciplinary European platform for multifaceted characterization of membrane transport that will be extendable to a range of membrane protein targets.;100000;100000;FP7-PEOPLE-2013-CIG;/MC-CIG;KUNGLIGA TEKNISKA HOEGSKOLAN;SE;;;/LIF;1;0;0;2;0;0 108486;327403;WATER AND TRANSITION;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IOF;FP7;River Basin and Water Circulation in the Transition to an Urban-Industrial Society: the Po Drainage Basin, 1860-2000;2013-08-16;2016-08-15;;"The research proposed aims at retracing the historical transformation of river basins and water circulation in the urban-industrial age, by integrating social and environmental sciences. The empirical case study will be the Po river basin, which hosts one of the most developed urban-industrial region in the EU, and which is surprisingly lacking of a comprehensive historical reconstruction. I will fill that void, retracing the genealogy of the present condition by looking at the interplays of social and environmental processes over the last two centuries. I will achieve this goal by: 1. retracing the historical development of agricultural, urban, and industrial uses of Po basin water; as well as the main actors, projects, and phases of the transformation; 2. mapping the changing geographies of water metabolic circulation in the Po river basin, related to the historical transformation of water uses in the transition to the urban-industrial society; 3. studying the impact of the transformation in water uses and circulation on the river basin hydro-ecosystem, and the consequences of this on the various set of human activities over time; 4. identifying the most relevant characteristics that can qualify the transformation in water socio-ecological metabolism in the transition to the urban-industrial society. This research will provide a comprehensive historical account of the Po river basin transformation from an environmental point of view. It will also implement an interdisciplinary analytical framework on river systems transformations and metabolic exchanges with urban-industrial societies: a crucial issue for European research and policies. The project will be carried out in the US and in Austria, under the guidance of the leading scholars Craig E. Colten (LSU), Fridolin Krausmann (AAU-SEC) and Verena Winiwarter (AAU-ZUG), ensuring a high-profile international and interdisciplinary career development for the fellow.";261326,4;261326,4;FP7-PEOPLE-2012-IOF;/MC-IOF;UNIVERSITAET KLAGENFURT;AT;;;/LIF;1;0;0;2;0;0 98329;267557;MODSIMCONMP;ONG;FP7-IDEAS-ERC;ERC-AG-ID1;FP7;Modeling, Simulation and Control of Multi-Physics Systems;2011-04-01;2016-03-31;;"This proposal is aimed at developing and analyzing a fundamentally new interdisciplinary approach for the modeling, simulation, control and optimization of multi-physics, multi-scale dynamical systems. The new innovative feature is to generate models via a network of modularized uni-physics components, where each component incorporates a mathematical model for the dynamical behavior as well as a model for the uncertainties, e.g. due to modeling, discretization or finite precision computation errors. Based on this new modeling concept also new numerical simulation, control, and optimization techniques will be developed and incorporated, that allow a systematic adaptive error control (including the appropriate treatment of different scales,and the uncertainties) for the components as well as for the whole multi-physics model. In order to cope with the differential-algebraic and multi-scale character of the systems we will develop and analyze remodeling techniques for the components as well as for the whole network including the uncertainties and special structures. The new remodeled systems will be designed such that they allow an efficient and accurate dynamical simulation with high order numerical integration techniques as well as efficient methods for model reduction and open and closed loop control. In an interdisciplinary corporation with colleagues from computer science and engineering we will extend the modeling language MODELICA to be able to incorporate the new features (in particular the uncertainties and modeling errors) and we also plan to implement the complete approach as a new software platform.";1899923,6;1899923,6;ERC-2010-AdG_20100224;/ERC-AG;TECHNISCHE UNIVERSITAET BERLIN;DE;;;/SCI;1;0;0;2;0;0 102097;267264;INVEST;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-COFUND;FP7;INternational VEnue for poSTgraduate education;2011-11-01;2017-04-30;;"The Universit? Vita-Salute San Raffaele (USR) is a vibrant and acclaimed private University in Milan, Italy, registered by the Italian Ministry of Research. Together with the San Raffaele Research Institute and the San Raffaele Hospital, both controlled by the San Raffaele Foundation hereafter referred to as HSR, it is part of the San Raffaele Biomedical Science Park, hereafter referred to as SRBSP. A specific agreement rules the interactions between the USR and HSR. All the USR Professors within the Faculties of Medicine, Psychology and Philosophy, and with the School of Biotechnology have an exclusive relationship with the San Raffaele Foundation in the aim of collaborative teaching and shared research strategies and clinical programs. All academic, research and clinical activities take place on the SRBSP campus. The SRBSP is renown as a leading research structure in the field of Molecular Medicine in Italy and worldwide. The mission of the SRBSP is integration and interdisciplinarity for excellence in teaching, innovation in research, and optimal patients care. SRBSP launched recently an International Postdoctoral Programme devoted to the development and support of an international community of postdocs, both national and non-nationals, recruited according to excellence standards. Through INVEST, USR is committed to further develop such program and to promote mobility by fostering the enrolment of both incoming postdocs (non-residents who have not resided in the country of the host organization for more than 12 months in the 3 years immediately prior to the deadline of the call) and Member State postdocs having carried out research in a third country for at least 3 years (reintegration scheme). The USR, given its position within SRBSP, offers a unique opportunity to be trained in cutting-edge research topics and state-of-the art techniques in a highly supportive, intensely collaborative and interdisciplinary environment. Postdocs will be recruited through merit-based transparent selection procedures and have the chance to freely choose the research topic of interest among those present within the Institute (see B1, page 5). As the SRBSP hosts both academic and corporate settlements, postdocs will have the opportunity to be trained in fields that span the domains of basic, applied, clinical and industrial research. In line with the commitment of USR to a life-long training of the future generation of EU-based scientists and science-related professionals, assigned projects will provide postdocs with new research skills also reaching out beyond research and into the worlds or scientific writing, communication, report preparation, grant writing, patent applications and project management. Funding by the European Union will thus increase the competitiveness of promising young scientists and will provide them with life-long career development opportunities and, by that, contribute to the growth of the Eu Higher Education Area.";2323060;929224;FP7-PEOPLE-2010-COFUND;/MC-COFUND;Universit? Vita-Salute San Raffaele;IT;;;"/SOC;/COO;/NET";1;0;0;2;0;0 104729;316975;SO2S;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-ITN;FP7;"""The Singlet Oxygen Strategy: sustainable oxidation procedures for applications in material science, synthesis, wastewater treatment, diagnostics and therapeutics""";2013-01-01;2016-12-31;;"'The SO2S network seeks to exploit Singlet Oxygen (1O2) as a green and benign oxidant for use in novel synthetic methodologies, crosslinking strategies, bioconjugation procedures and materials production. The chemistry described herein generates the means to both understand and influence biological systems by providing probes and reagents – from analytical methods to new drugs - and to modulate materials towards optimal properties. Training in this area is highly interdisciplinary in nature requiring the joint efforts and contributions of chemists, physicists, biologists and material scientists. Ultimately our understanding and further development of singlet oxygen mediated oxidations should lead to useful applications in the fields of organic chemistry (improved routes towards natural products), medicinal chemistry (targeted delivery and novel diagnostics), physical chemistry (controlled singlet oxygen generation), and materials science (novel materials for water treatment and new arrays for improved diagnostics). The global objective of this network is to train young researchers to become skilled individuals that meet the current challenges of working in an interdisciplinary industrial environment wherein chemistry often forms the basis, but where it is utilized in a truly diverse range of applications.'";3382553,02;3382553,02;FP7-PEOPLE-2012-ITN;/MC-ITN;UNIVERSITEIT GENT;BE;"BIOTEZ BERLIN-BUCH GMBH BIOCHEMISCH-TECHNOLOGISCHES ZENTRUM;ECOSYNTH;PANEPISTIMIO KRITIS;UNIVERSIDADE DE AVEIRO;BUNDESANSTALT FUER MATERIALFORSCHUNG UND -PRUEFUNG;BIOSENSOR S.R.L.;UNIVERSIDAD AUTONOMA DE MADRID;INOVAPOTEK, PHARMACEUTICAL RESEARCH AND DEVELOPMENT LDA";"DE;BE;EL;PT;IT;ES";/LIF;1;0;0;2;0;0 105175;299957;DISCANT;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IIF;FP7;High-energy dissipative soliton dispersion-managed fibre laser based on carbon nanotubes;2013-04-18;2015-04-17;;"'The proposed research program aims at knowledge transfer from a Fellow with strong expertise in mode-locking fibre lasers using carbon nanotubes to the EU host who can combine this knowledge with own expertise in soliton theory and dispersion management for advancing the fast growing field of fibre lasers. The overall research objective is to develop new concepts, techniques and approaches to the new design of high-energy fibre lasers based on a transfer of the methods of nonlinear science into the field of optical engineering. The proposed interdisciplinary project will link optical engineering laser research to applied mathematics, nonlinear wave physics and nano-material physics. The academic profile of the applicant ideally matches the proposed research project. Dr. Webb as a host will supervise the experimental research in the project and Prof. Turitsyn as a co-supervisor will coordinate theoretical studies on dispersion-managed dissipative soliton fibre lasers. The project is split into four distinct work packages (WPs) targeting four types of research goals and corresponding knowledge transfer. • WP1 targets fundamental properties of fibre laser systems. • WP2 will create a platform for fabrication of carbon nanotube saturable absorbers for photonic applications. • WP3 will focus on demonstration of advanced practical high-energy fibre laser systems. • WP4 will aim to optimize noise performance of the laser systems and broaden their operating wavelength range. The proposed interdisciplinary program will make important contributions both to science and technology and European excellence and competitiveness, namely, the project: • will enhance EU research in laser science, optical communications and nonlinear photonics; • will establish an internationally leading position for EU in the science, application and production technologies of fibre lasers; • will lead to a new level of high-brilliance laser sources important for a range of applications.'";209033,4;209033,4;FP7-PEOPLE-2011-IIF;/MC-IIF;ASTON UNIVERSITY;UK;;;/SCI;1;0;0;2;0;0 109211;604063;HEALTHPAC;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-ITN;FP7;Perception and Action in Health and Disease;2014-01-01;2017-12-31;;"With the strong growth of the aging population, sensory-motor loss and neurodegenerative disorders will affect an increasing number of Europeans, which will have huge impact on society. HealthPAC is an integrated, international and interdisciplinary network of renowned perception-action (PAC) research labs, clinical departments, and industry. Its mission is to understand the neural mechanisms of sensory-motor control and its disorders, and to utilize this knowledge to enhance the quality of life. Our network trains ESRs to become excellent PAC-scientists who: (i) set up and perform high-quality research in sensory-motor neuroscience, (ii) can translate and apply their knowledge to clinics and rehabilitation centers, and (iii) understand the processes to develop innovative products that improve the quality of life in health and disease. Students participate in research training programs, tailored to their individual interests, and are brought in intensive contact with European companies and institutes to improve and extend their future career prospects. The PAC team of the Donders Institute (DI) is particularly suited to organize this training program. It studies sensory-motor integration in an interdisciplinary setting with unique state-of-the-art methodologies in research labs and clinical departments of eleven established neuroscientists. Moreover, the DI has a dedicated Graduate Program in which ESRs are trained in advanced research and analysis techniques, and acquire an academic and ethical attitude towards applying systems neuroscience. Associate Partners contribute relevant knowledge from the private sector by teaching HealthPAC students about sensory-motor related product development, legal issues, management and marketing, and offer well-defined research secondments. Students are intensively mentored and prepared for their future careers, either as a PAC-scientist in an academic or clinical setting, or as innovative researcher in the private sector.";3325547,5;3325547,5;FP7-PEOPLE-2013-ITN;/MC-ITN;STICHTING KATHOLIEKE UNIVERSITEIT;NL;;;/LIF;1;0;0;2;0;0 108970;329837;NEUCOD;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IEF;FP7;Information-theoretic approach to infer encoding patterns in a decision making process;2013-09-01;2015-08-31;;The question of how stimuli and actions are encoded in the neuronal signals of the brain is at the central core of neuroscience research. In particular, very little is known about the mechanism for which a given decision posterior to a stimulus is manifested in the brain activity. Nowadays, simultaneous recordings of neurons in different brain regions bring an exceptional dataset to investigate the complex encoding mechanisms that underlie a decision making process. In the present project, the candidate will have exclusive access to one of these datasets which consists of brain recordings in primates during a decision making task. The candidate will employ his expertise in some areas of information theory and coding to formulate a novel hypothesis to be tested on these available data. This hypothesis states that causal interactions between neurons in a population encode information about decisions. This interdisciplinary line of investigation represents a changing point in the candidate’s career. On the one hand, the candidate will be trained in the neurophysiological aspects of the problem. On the other, he will develop emerging methods to capture causal interactions between neuronal responses and then represent the hypothesized “encoding patterns”. From a scientific point of view, this project will provide one of the key tools to understand information processing in a decision-making process and study sources of brain disorder based on the dynamics of encoding patterns. More generally, the present project will launch the candidate’s career in an interdisciplinary field that has potential application in academia and industry research, as well as will foster the collaboration between the information theory and the computational neuroscience communities, thus making this research area in Europe more competitive and attractive for future students and researchers.;166336,2;166336,2;FP7-PEOPLE-2012-IEF;/MC-IEF;UNIVERSIDAD POMPEU FABRA;ES;;;/SCI;1;0;0;2;0;0 108623;331051;Credit and Republic;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IEF;FP7;Public Debt and the Republic: Florentine Political Thought and Public Finance from 1470 to 1537;2013-06-01;2015-05-31;;"The need to develop tools for the understanding of public finance has been highlighted by the financial crisis that broke in 2008. The research ambition of this project on the origins of political economy is to show that the intellectual history of public finance can generate such tools. Its main objective is to produce a monograph entitled *Public Debt and the Republic: Florentine Political Thought and Public Finance from 1470 to 1537*, which takes financial thought back to its roots, at a moment when the development of democratic institutions came to contradict the development of public credit. As such it also illuminates an understudied aspect of the political thought of the ‘Machiavellian Moment’, which redirected the tradition of classical Republicanism, thus defining one of the cornerstones of European modernity. This objective is achieved through: • exploitation of the Florentine archives. These preserve unique and unexplored materials which render feasible the in-depth reconstruction of the foundation of modern financial thought and practice • collaboration with the host institute. The Centre for the Study of the History of Political Thought (Queen Mary, University of London) hosts one of the largest concentrations of specialists in this field. The proposed investigation contributes to a central interdisciplinary research project of the Centre, on ‘Popular Sovereignty’. Undertaking the proposed project at the host institute allows the applicant to: • resume his European academic career after a five-semester hiatus researching and teaching in the USA and South Africa • further his career options in order to attain an academic position at a leading European institute • enhance his interdisciplinary skills, intertwining the history of ideas and the study of systems of administration • optimize his theoretical reflection, adept at both transnational and transhistorical analysis • acquire systematic knowledge of the financial culture of early modern Florence.";309235,2;309235,2;FP7-PEOPLE-2012-IEF;/MC-IEF;QUEEN MARY UNIVERSITY OF LONDON;UK;;;/SCI;1;0;0;2;0;0 92354;239844;QOM;ONG;FP7-IDEAS-ERC;ERC-SG-PE2;FP7;Quantum Optomechanics: quantum foundations and quantum information on the micro- and nanoscale;2009-11-01;2014-10-31;;Quantum states of mechanical resonators promise access to completely new experimental regimes of physics: from unprecedented levels of force sensitivity to the generation of macroscopic quantum superpositions of massive objects containing up to 10^20 atoms. This opens up not only exciting possibilities for novel applications but also allows to (re)address fundamental questions of quantum physics, in particular its relation to the classical world. For this reason the preparation and control of mechanical quantum states has long been an enticing but far fetched goal of breakthrough character. With the advent of micro- and nano-mechanics this goal is at the verge of becoming an experimental reality. The last few years have witnessed unprecedented global progress in pushing mechanical systems towards the quantum regime. A thriving interdisciplinary field has emerged that aims to exploit the tremendous potential that lies in the control of mechanical quantum states. The main idea of this proposal is to combine the tools and concepts of quantum optics with micro- and nano-mechanical systems. Such combination provides a unique and powerful approach that allows, with a minimal set of experimental interactions, universal quantum control over mechanical systems via opto-mechanical interactions. The feasibility of the approach has recently been verified by us and by several other groups worldwide in a series of experimental demonstrations of mechanical laser cooling. The main objective of the proposed research is to go significantly beyond the current state-of-the-art and to develop the field of quantum-opto-mechanics to its full extent, both in experiment and theory. This will also increase the European visibility in this highly topical area of research. My professional background in both solid-state physics and quantum optics and quantum information will be of additional help in this highly interdisciplinary endeavour.;1670904;1670904;ERC-2009-StG;/ERC-SG;UNIVERSITAT WIEN;AT;;;"/PSE;/SCI";1;0;0;2;0;0 105492;316472;NORA;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-ITN;FP7;NORA - Nitrous Oxide Research Alliance Training Network;2013-01-01;2016-12-31;;"The fate of anthropogenic nitrogen is at the core of our environmental predicament. Human activities have more than doubled the annual input of reactive nitrogen to the biosphere compared to prehistoric levels, causing escalating emissions of nitrous oxide (N2O) which contributes to global warming and depletion of stratospheric ozone. Ultimately, anthropogenic nitrogen will return to the atmosphere, either as N2, N2O or NO, which are the gaseous products of microbial red/ox-transformations of mineral nitrogen. The N2/N2O/NO product ratio of these transformations is controlled by the ecology and regulatory biology of the organisms involved, modulated by environmental factors. We need better understanding and quantification of these processes to improve our chances to reduce N2O emissions from managed ecosystems (agriculture and waste treatment systems). Such progress requires interdisciplinary scientific approaches in collaboration with the fertilizer and waste-industries. NORA comprises the strongest research groups in Europe regarding the biochemistry, biotechnology, physiology and ecology of N-transforming microbes in soils and wastewater systems, the R&D of leading fertilizer-, waste treatment- and robot- industry. Major goals are to • improve our understanding and predictive ability regarding the ecology and regulatory biology of microbes involved in oxidation and reduction of mineral N species affecting atmospheric N2O. • produce a new generation of nitrogen researchers, within both academic and private sectors, with inter- and cross-disciplinary skills and understanding and appreciation of both fundament science and its direct application to environmental, industrial and societal issues. • exploit the power of fundamental scientific understanding, developed through interdisciplinary research and close interactions between academia, industry and policy makers, to generate specific recommendations, strategies and solutions to reduce nitrous oxide emissions.";3365699,78;3365699,78;FP7-PEOPLE-2012-ITN;/MC-ITN;NORGES MILJO-OG BIOVITENSKAPLIGE UNIVERSITET;NO;"THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN;UNIVERSITY OF EAST ANGLIA;STICHTING VU;YARA GMBH & CO. KG;BIOCLEAR BV;SVERIGES LANTBRUKSUNIVERSITET;ECOLE CENTRALE DE LYON;INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE;GOETEBORGS UNIVERSITET;TECHNISCHE UNIVERSITEIT DELFT";"UK;NL;DE;SE;FR";/LIF;1;0;0;2;0;0 99111;276062;4CB;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-IEF;FP7;Cognitive Common Currency or Contextual Bargaining ? A new model for food preferences;2011-06-01;2013-05-31;;"'Research has for long focused on what people choose, not how they choose. In the domain of food choices, like elsewhere, the dominant model is that preferences are comparative judgments between quantities of sensory pleasure. Significant development lately in the cognitive neurosciences on the many roles of hedonic systems in choices and behavior have put pressures on this classical ‘common currency’ (Cabanac,1992) model of decisions. They stress the variety of low-level, automatic, sub-personal influences bearing on food choices, and show that behaviour can be ‘nudged’ in context (Thaler & Susstein, 2008). This still doesn’t address the nature and the role played by food preferences at the conscious, personal level. The objective is to provide such a model. The timely interdisciplinary methodology draws on cognitive sciences and philosophical models of the mind, advancing bridging the gap between the study of evaluative and perceptual processes. Guided by recent models in multi-modal flavour perception (Auvray &Spence, 2007), 4CB defends a model of contextual bargaining for food choices. It combines conceptual and experimental approaches, and is set up in the interdisciplinary Center for the Study of the Senses. It defends and puts to test two key proposals by distinguishing different kinds of preferences (contextual/automatic/reflective) and contextual influences on them (multisensory context and cognitive context of consumption). Consequences for the wider concept of ‘preferences’ and impact on heath and food policies are integral to the project.'";192349,6;192349,6;FP7-PEOPLE-2010-IEF;/MC-IEF;UNIVERSITY OF LONDON;UK;;;"/EMP;/EDU;/NET";1;0;0;2;0;0 108689;315997;INTEGRA-LIFE;ONG;FP7-REGPOT;REGPOT-2012-2013-1;FP7;Integrating research in molecular life sciences at the University of Zagreb;2013-06-01;2016-11-30;;"INTEGRA-LIFE will functionally integrate and reinforce the most promising research groups in glycoproteomics, epigenetics, genetic engineering, biochemistry and bioinformatics through collaboration with 13 eminent European partnering organisations. By fostering collaboration between different Faculties and scientists working in different disciplines we will promote multidisciplinary research that can enable significant progress from current state of the art. The procurement of new generation of instruments for the analysis of DNA (next generation sequencer), glycans (mass spectrometer) and macromolecular interactions (thermophoresis), as well as advanced computer cluster for data analysis will enable our participating researchers. Our main strength is the already demonstrated excellence of our participating researchers in several complementary areas of molecular life sciences (glycoproteomics, epigenetics, genetic engineering, biochemistry and bioinformatics). Significant investments in both equipment and human resources in the past years enabled creation of a considerable research potential which will be further increased. The proposed integration of research efforts of 24 participating principal investigators into four strategic research priorities creates the opportunity to form a respectable critical mass of researchers and infrastructural capacity which would enable the most ambitious interdisciplinary research projects. Specific opportunity for rapid progress exists in the field of glycome analysis where we are currently one of the leading laboratories in the world. Through the proposed integration of researchers working in glycoproteomics, bioinformatics and epigenetics we have the chance to form interdisciplinary team with unique set of competences and become world leaders in the field of complex genetics and epigenetics of protein glycosylation. This would significant increase the visibility of UNI-Zagreb in the ERA and enable us to take leading roles in large international consortia and FP projects.";3615011,2;3224464;FP7-REGPOT-2012-2013-1;/CSA-SA;SVEUCILISTE U ZAGREBU;HR;;;/SCI;1;0;0;2;0;0 109153;319130;BIOQ;ONG;FP7-IDEAS-ERC;ERC-2012-SyG;FP7;Diamond Quantum Devices and Biology;2013-07-01;2019-06-30;;"Many of the most remarkable contributions of modern science to society have arisen from interdisciplinary work of scientists enabling novel imaging and sensing technologies (NMR, X-ray diffraction, electron microscopy). BioQ will revolutionize the state of the art to create novel sensing technologies for the broad field of life sciences research that provide unprecedented access and insight into structure and function of individual bio-molecules under physiological conditions and apply these to the observation of biological processes down to the quantum level and with atomic resolution. At this level quantum properties are predicted to play an important role for the function of biological systems subject to environmental noise. BioQ will unravel the interplay of quantum coherent dynamics, molecular vibrations and environmental noise due to molecular vibrations in biological processes and design and carry out experimental tests of its predictions. BioQ will achieve new levels of understanding and control of biological systems, culminating in new ways to interface biological systems with quantum devices. To this end BioQ will exploit the ability of biological systems to arrange themselves into highly ordered structures to form novel hybrid materials of functionalized nano-diamonds that are capable of harnessing complex quantum dynamics at room temperature. A deeper understanding of biological processes will open new roads towards drug design and bio-imaging. The elucidation of energy transport processes and dynamics may pave the way towards the design of more efficient light harvesting systems. Self-assembled hybrid bio-quantum devices provide a novel perspective towards quantum nanotechnology. The broad challenges that this ambitious programme present will be solved by an interdisciplinary team led by three PIs from experimental solid-state physics, theoretical quantum physics and bio-chemistry whose combination of expertise is essential for the success of BioQ.";10293309;10293309;ERC-2012-SyG;/ERC-SyG;UNIVERSITAET ULM;DE;;;/SCI;1;0;0;2;0;0 90262;226528;THIRDWAVEHCI;ONG;FP7-IDEAS-ERC;ERC-AG-PE6;FP7;Third Wave HCI: Methods, Domains and Concepts;2009-04-01;2014-12-31;;This proposal is for interdisciplinary research that will help bring to maturity the emerging paradigm of third-wave HCI , which addresses interaction as situated meaning-making in everyday life. With my established interdisciplinary research team, I will design prototypes that show how third-wave thinking is relevant for domains of recognised importance to help bring this paradigm to the centre of HCI. We will develop an integrated set of tactics and orienting concepts based on our practice to elucidate and support research and design in third-wave HCI. Crucially, we will develop a new methodology for this research, based on the deployment and study of 50 100 batch-produced prototypes in real-world situations. This will mark a significant leap forward, allowing prototype technologies to be studied using social scientific and design-led methods in field trials several orders of magnitude larger than normal a development from which third-wave HCI, with its commitment to multiple, local appropriations, will benefit enormously. The project will be centred around two Case Studies in which we will develop robust and highly finished prototypes, batch produce them in large numbers, deploy them in large-scale field studies with members of the general public as well as specialist commentators, and use a variety of traditional and experimental methods to capture their experiences. The first Case Study will produce a suite of electromechanically extended sensors that provide resources for environmental awareness in the home without being judgmental or didactic. The second Case Study will develop mobile devices that display readymade, location-based information to provide a behind the scenes view of local neighbourhoods. When dozens of these prototypes are in use simultaneously, we will be able to observe as communities of practice form, and a hundred different stories emerge, leading to a transformative coming-of-age for third-wave HCI.;2439757;2439757;ERC-2008-AdG;/ERC-AG;GOLDSMITHS' COLLEGE;UK;;;"/PSE;/ICT;/TEL;/NET";1;0;0;2;0;0 98922;272563;P4-MEDICINE@EU;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-IEF;FP7;Evaluation of a Best Practice Model for Personalized Health Care within Public Health Genomics;2011-05-01;2014-02-11;;"'The research area of the applicant is on personalized health care in complex diseases, their underlying genomic basis and its interaction with other contributing factors including life style. The personal career goal of the applicant is to become a leading researcher in Europe by developing an innovative, effective and interdisciplinary model to prevent diseases and improve health status of European citizens. Within this goal, the researcher developed a personalized health care model at GENAR Institute for Public Health and Genomics Research, Ankara, Turkey. It is based on the use of public health genomics (PHG) tools and concepts to stratify individuals according to risk groups, prevent diseases and detect them early. It has been piloted as a health service to 500 individuals since 2008. The European challenges of the project are twofold: There is a need for policy research to analyze how to adapt the model for the implementation in European health systems. There is also the need to prepare policymaking in Europe for the implementation of personalized interventions. The GENAR model, which had been identified as a best practice model in this field in Europe, will be used as an example to develop the methodologies needed to close these gaps in Europe in a timely manner. By contributing to the valorisation in PHG for the benefit of population health, this interdisciplinary project is of high European added value and will increase European competiveness. Research and training will be carried out at the European Center for Public Health Genomics(ECPHG) at Maastricht University, which is a European Centre of Excellence in PHG. It provides hands-on training for the researcher to develop unique knowledge and skills on the evaluation of a practice model in personalized health care and policy research methodologies in PHG. This will complement her current skill set on R&D in complex diseases and enable her to reach professional maturity as a competent scientist in Europe.'";178340,8;178340,8;FP7-PEOPLE-2010-IEF;/MC-IEF;UNIVERSITEIT MAASTRICHT;NL;;;"/EMP;/EDU;/NET";1;0;0;2;0;0 99573;274922;W&S;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-IEF;FP7;Writing & Statues. Palaeographic Analysis and Historical Perspectives on Greek and Latin Honorary Inscriptions from Ancient Sicily (I BC - VII AD);2012-09-24;2014-09-23;;"'The main purpose of this research is the realization of a corpus of Greek and Latin epigraphic documents carved on stone in Sicily under the Roman Empire (post 27 BC – 650 AD), making use of a new interdisciplinary approach. The target of this study is twofold; it will allow me to interpret and evaluate the meaning(s) of Sicilian inscriptions. A) The first need is to collect and study inscriptions on stone, paying attention to their style and content. I shall outline the palaeographic evolution during the imperial age, and then I shall pinpoint the chronology also for those that have not yet been dated. B) The second need arises from the first: the largest part of Sicilian documents on stone were carved on the bases of statues erected in public area to honour emperors, dignitaries and benefactors. In order to understand the correct meaning of these inscribed monuments it is necessary to extend my research to the bases of statues themselves and to the contexts in which they once stood. At the same time, I will have to interact the ways in wich word and image interact in the language of honorary statues during the Roman Imperial period. All this will be the topic of a specific thematic study. This project is original in several ways: 1) It permits to go beyond existing palaeographic studies and to sketch an evolution of letter-forms during the Imperial age, taking as a case study Sicily and a particular class of epigraphs (those carved on stone), in order to suggest a chronology for the inscriptions that have not yet been dated. 2) It investigate the inscriptions carved on the statue-bases and their original context, making use of literary sources and archaeological data. 3) It permits to answer questions about the relationship between word and image in the statuary of the Roman Imperial age. A full understanding of honorary inscriptions would be impossible without an interdisciplinary approach.'";202392,8;202392,8;FP7-PEOPLE-2010-IEF;/MC-IEF;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;UK;;;"/EMP;/EDU;/NET";1;0;0;2;0;0 96214;268463;CONTACT AND CHANGE;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-RG;FP7;The Irony of Harmony: Examining how Experiences of Intergroup Contact can Undermine Potential for Social Change toward Equality;2010-10-01;2014-09-30;;Conflict and tensions between members of different groups are critical problems facing societies today. One of the most important contributions of social psychology for improving intergroup relations has been contact theory, which offers that cooperative and friendly intergroup encounters can improve attitudes between groups. The theory stimulated a vast amount of research and generated widespread optimism about the potential of creating more tolerant societies through contact interventions. Recently, however, prominent scholars have argued that while contact may be a successful tool for prejudice reduction, it may contribute little toward increasing social justice and group equality. These views, bringing together insights from social psychology, political science and sociology, drew attention to a disjuncture between the effects of contact and psychological foundations of social change. Although theorized about, these processes received sparse, and mainly correlational empirical support. The proposed research is the most detailed and most rigorous investigation yet of the consequences of intergroup contact for social change. It will be led by the applicant in close collaboration with a European collaborator and will involve a fully controlled laboratory study conducted in Israel, a longitudinal study in the U.S., and two cross-sectional studies in both India and Israel. Findings from this research, which would generalize across a variety of intergroup settings, are likely to have important theoretical as well as practical implications for interventions aimed at creating long-term social justice in societies marked by social inequality. The collaborative nature of the project involving experts residing in the US, the UK and India along with its interdisciplinary elements, is consistent with the aim of creating internationally competitive knowledge and developing ‘state of the art’, interdisciplinary research capacity within the EU.;100000;100000;FP7-PEOPLE-2010-RG;/MC-IRG;INTERDISCIPLINARY CENTER (IDC) HERZLIYA;IL;;;/SCI;1;0;0;2;0;0 107722;330418;GRAPHITE4MED;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IEF;FP7;Aerographite as scaffold material for regenerative medicine;2013-04-01;2015-03-31;;We propose an interdisciplinary project with the objective to explore the feasibility of aerographite as scaffold material for tissue engineering in regenerative medicine with special focus on directed cell growth. Aerographite is a novel carbon based material that consists of a seamless interconnected network of microtubes. The project is motivated by promising developments of related carbon materials (carbon nanotubes and graphene) in biomedical applications. Aerographite is a potential candidate for tissue engineering, as it can be fabricated in a highly controllable manner to create various macroscopic 3-D shapes. Tailored microarchitectures can be realized that offer penetrability and accessibility of surfaces. These features are key factors for 3-D tissue growth. The 2-year project will be realized in three stages: 1. Material characterization and chemical surface modification to impart aqueous compatibility, 2. Biofunctionalization for specific cell adhesion, and 3. Quantification of cell adhesion and growth on functionalized scaffolds. All tasks are highly interdisciplinary and combine aspects of materials science, chemistry, biology and biophysics and medicine as evident in the variety of analytical techniques that will be employed. Aerographite structures and their functionalization will be investigates with Raman spectroscopy, scanning electron microscopy (SEM), scanning probe microscopy (SPM), and contact angle measurements. SPM, confocal fluorescence microscopy and environmental SEM will be used to assess cell growth on aerographite. Biological assays will be applied to evaluate biocompatibility and cytotoxicity. For the success of the project the applicant can profit from her previous collaborations with European research groups and the excellent research environment at the host university. New collaborations and acquisition of new skills and knowledge will complement her scientific profile and enable her to start a junior group in the near future;161968,8;161968,8;FP7-PEOPLE-2012-IEF;/MC-IEF;CHRISTIAN-ALBRECHTS-UNIVERSITAET ZU KIEL;DE;;;/SCI;1;0;0;2;0;0 97546;264873;FUNEA;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-ITN;FP7;FUnctional Nitrides for Energy Applications;2011-02-01;2015-01-31;http://www.funea.tu-darmstadt.de;The FUNEA vision is to develop an integrated and multidisciplinary research and training programme in the field of inorganic nitrides for energy applications. In terms of fundamental research, the FUNEA aims to advance the state-of-the-art knowledge and understanding of inorganic nitrides and mixed nitride-anion systems by achieving the ability to synthesise, manipulate, characterize, understand and model binary and ternary nitrides and oxonitrides with functional properties. By this a breakthrough in the nitride chemistry will be achieved steering in a new era for materials with advanced functionality and exceptional levels of performance. In terms of technological applications, the FUNEA focuses on the energetic applications of novel nitride-based materials with this addressing the main needs of the 21st century. To meet this vision, eight European academic research groups with complementary expertise in the synthesis, processing and characterization of materials and five industrial partners, each of whom have made a commitment to study these new functional nitrides, have decided to create a network of scientific cooperation with the following goals: (i) to create an interdisciplinary approach to the synthesis, processing and characterization of novel nitrides for energy applications, (ii) to train high-quality young researchers, experienced in the interdisciplinary science of the nitrides. These young professionals will lead the field forward and onward to its bright future in the European science and technology. Specifically, FUNEA aims to train 11 ESRs and 2 ERs with an overall target of 40% women researchers, and (iii) to establish a European network of scientists in academic institutes and industry in the field of inorganic nitrides, that will continue to grow and enhance European competitiveness over the next years.;3057346,58;3057346,58;FP7-PEOPLE-2010-ITN;/MC-ITN;TECHNISCHE UNIVERSITAT DARMSTADT;DE;"UNIVERSITE DE MONTPELLIER;USTAV ANORGANICKEJ CHEMIE SLOVENSKA AKADEMIA VIED (Institute of Inorganic Chemistry, Slovak Academy of Sciences);UNIVERSITA DEGLI STUDI DI PADOVA;MDA ILERI TEKNOLOJI SERAMIKLERI SANAYI TICARET LIMITED SIRKETI;FAURECIA EMISSIONS CONTROL TECHNOLOGIES GERMANY GMBH;UNIVERSITA DEGLI STUDI DI TRENTO;UNIVERSITAET BAYREUTH;UNIVERSITE MONTPELLIER 2 SCIENCES ET TECHNIQUES;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;AZ ELECTRONIC MATERIALS (GERMANY) GMBH;STOCKHOLMS UNIVERSITET";"FR;SK;IT;TR;DE;SE";"/EDU;/NET";1;0;0;2;0;0 103484;298656;CETH;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IEF;FP7;COMPARATIVE EDUCATION THEORY;2013-04-01;2015-03-31;;"'The proposed project is an interdisciplinary theoretical investigation in the field of comparative education studies. The main purpose is to create a knowledge base intended to contribute to our understanding of education systems across cultures, under the conditions created by the Europeanisation and globalisation of education policy. These novel conditions indicate that it is time to improve our theoretical and methodological tools in Comparative Education, and allow for the production of new knowledge in this field. In attempting to do so, the project sets three main objectives: to generate a new theoretical understanding of education systems as social institutions; to produce an original account of the epistemological background of educational comparison; to propose a theoretical approach with regard to the comparability of education systems, now increasingly subject to transnational forms of policy making. To achieve these objectives the project will: theorise on the instituting of education systems, drawing on a variety of disciplines; engage with cross-historical and cross-cultural inquiry into the genesis and expansion of education systems and of educational comparison in Europe; apply its theoretical approach and develop it further through this inquiry. The proposal coordinator has considerable research and teaching experience in this field. The IEF, as outlined in 2011 Work Programme, will give him the opportunity for competence development in theoretical and interdisciplinary research which will enable him later on to make original contributions to the field. Moreover, the IEF will assist him to achieve a senior position at his home institution and establish his own research centre in Comparative Education. The researcher will be hosted by Humboldt University, which, due to the cutting-edge theoretical work of Jürgen Schriewer in the field, is perhaps the best and certainly the most appropriate place to carry out this project.'";231547,2;231547,2;FP7-PEOPLE-2011-IEF;/MC-IEF;HUMBOLDT-UNIVERSITAET ZU BERLIN;DE;;;/SCI;1;0;0;2;0;0 88285;215446;DESIRE;ONG;FP7-PEOPLE;PEOPLE-2007-1-1-ITN;FP7;Creative Design for Innovation in Science and Technology;2008-09-01;2012-08-31;;"Today’s economic environment is characterised by a high level of competitiveness emphasised by globalisation which enables access to low cost skills and services. Competing in a global economy and facing the challenges of tomorrow requires a movement towards innovation that recognises the key importance of creativity and design. The proposed project aims to establish an interdisciplinary network of researchers investigating creative design in various applied domains including interaction design, industrial design and arts design. The goal is to create an internationally recognised programme of research that will expand the current state-of-the-art in creative design. This research proposal aims to strengthen the dialogue among the different disciplines contributing to creative design and to provide a basis for interdisciplinary investigation of technological creativity and innovation. This network seeks to provide new researchers with knowledge and skills needed to investigate and support creative design, as well as apply it in practice in technological fields such as human–computer interaction and ubiquitous computing. The research programme will focus on the following topics: Creative problem solving in design; Studying creative design process; Supporting creativity; Modelling creativity; and Innovation in teaching/learning design.";3243287,69;3243287,69;FP7-PEOPLE-2007-1-1-ITN;/MC-ITN;LANCASTER UNIVERSITY;UK;"UNIVERSIDADE CATOLICA PORTUGUESA;UNIVERSIDADE DE AVEIRO;COPENHAGEN BUSINESS SCHOOL;PHILIPS ELECTRONICS NEDERLAND B.V.;UNIVERSITA DEGLI STUDI DI MILANO;TECHNISCHE UNIVERSITEIT EINDHOVEN";"PT;DK;NL;IT";"/EMP;/SOC;/EDU";1;0;0;2;0;0 92108;235461;LEGAPOLIS;ONG;FP7-PEOPLE;FP7-PEOPLE-IEF-2008;FP7;Civil society and the mobilization of European human rights: Minorities and Immigrants in the Strasbourg Court;2010-09-01;2012-08-31;;LEGAPOLIS seeks to understand and explain how by interpreting the Convention the European Court of Human Rights has over time expanded and transformed from a primarily political and institutionally weak international regime into a binding legal system of transnational rights review. It explores in a systematic way the causes and consequences of its expansion by specifically focusing on the Court’s burgeoning case law pertaining to minorities, immigrants and asylum seekers. Through a series of case studies and comparative analyses, LEGAPOLIS explores the proposition that the Court’s expansion and institutionalization has been spanned by processes of social mobilization and repeat litigation on the one hand, and progressively more expansive interpretations by the Strasbourg Court. LEGAPOLIS employs a fundamentally interdisciplinary approach that extensively draws from legal studies but employs a political science and political sociology perspective with insights from European integration studies. In taking a bottom-up approach centring on the role of civil society, it shall make a distinct contribution to existing research on human rights and European integration, particularly from an interdisciplinary and contextual approach to law and rights that is highly undeveloped in Europe.;;227541,01;FP7-PEOPLE-IEF-2008;/MC-IEF;EUROPEAN UNIVERSITY INSTITUTE;IT;;;"/SCI;/EMP";1;0;0;2;0;0 103678;302290;LUCES;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IOF;FP7;Land Use Change, Environment and Society: a integrated framework for economic assessment;2013-01-10;2016-01-09;;"This highly interdisciplinary research project examines one of the most fundamental problems in natural resource and environmental economics: the optimal use of land. Land management raises major trade-offs between public and private interests. Agriculture provides the paramount illustration of these trade-offs. Ownership belongs to the private sector, but has significant implications for the society, generating external costs, (such as changes in wildlife habitats and deforestation), as well as external benefits (like the provision of recreational opportunities and the storage of greenhouse gases, GHG). The central objective of this research is to develop an integrated framework for the economic analysis of decisions concerning agriculture, land use change and associated environmental impacts. It will be based on a novel methodology for economic analyses, including joint models of: a) agricultural production, land use and incomes; b) GHG emissions and c) open-access recreation demand and values. These econometric models will be integrated in a spatially-explicit framework which will encompass both private and social values arising from agricultural land use change. The approach will be demonstrated via policy-relevant scenarios, generated as changes in the main determinants of land use, including market, policy and environmental drivers. The project will contribute to the objectives of the FP7 People Programme by: 1) producing innovative and interdisciplinary research with high policy-relevance, which will be effectively disseminated with a series of outreach activities; 2) allowing the fellow to gain new skills and additional training in advanced econometrics and environmental economics and become one of the EU leading experts in a fast-growing field of research; and 3) establishing a long-term collaboration between two centres of excellence such as UCSD (San Diego, USA) and UEA (Norwich, UK) enhancing the European quality of research.";271943,7;271943,7;FP7-PEOPLE-2011-IOF;/MC-IOF;UNIVERSITY OF EAST ANGLIA;UK;;;/SCI;1;0;0;2;0;0 101224;272962;Sparks of Reason;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-IOF;FP7;Sparks of Reason. Urban Culture, Vernacular Rationalism and New Perspectives on the Enlightenment;2012-08-01;2015-01-31;;"Current debates on the Enlightenment and its influence on present-day society call for an informed scholarly response. What exactly is the Enlightenment? What are its historical roots and how is it being used in current public debate? This project aims to contribute to such a response by introducing a specific tradition of urban lay philosophy—namely ‘vernacular rationalism’ in the Netherlands—as a new factor in our understanding of the rise and meaning of Enlightenment. As a secondary objective, the project aims to assess the relevance of lay philosophy generally for the understanding of early modern society and culture. This is achieved by (1) examining the philosophical and socio-cultural legacy of 16th-century vernacular rationalism and its function in the Dutch Golden Age, (2) using this to enhance our understanding of the Enlightenment as a historical phenomenon and as a historiographic notion, and (3) turning the case of vernacular rationalism into an informed illustration of the relevance of lay philosophy generally for early modern studies. Underpinning these research objectives is the strong conviction that it should be natural for intellectual historians to see philosophical ideas as responses to social, religious, political and other issues. The project will therefore reflect an interdisciplinary approach, seeking to integrate—under close monitoring of highly experienced multi/interdisciplinary supervisors—knowledge and methods from various fields of study. As such, it stands at the crossroads of philosophy, culture history and literary studies. By assessing, refining and correcting our knowledge of the foundations of present-day European society and culture, the project will enhance excellence and increase understanding on a subject directly relevant to the ERA and the EU at large. The mobility is genuine, as its aim is my training in a first-rate US environment and my re-integration into an outstanding multidisciplinary environment in Europe.";188239,6;188239,6;FP7-PEOPLE-2010-IOF;/MC-IOF;UNIVERSITEIT UTRECHT;NL;;;"/EMP;/SOC;/COO";1;0;0;2;0;0 92160;237230;EPIDEMICS;ONG;FP7-PEOPLE;FP7-PEOPLE-IOF-2008;FP7;Epistemology and Democracy in Complex Societies (EPIDEMICS);2010-01-01;2012-12-31;;It is often said that the sciences should be brought into democracy (EC 2000), but conceptual frameworks for making sense of that aspiration are surprisingly underdeveloped. There is a now a wealth of middle-range theoretical and empirical research on new democratic institutional innovations addressing themes such as genetic modification, biosecurity, reproductive technologies and genetic testing, but there has been little synthesis and comparative analysis of these contributions in terms of democratic theory. This project will fulfil the need for a richer theoretical account of democratic theory in the context of scientific governance, drawing on sociology of knowledge and political theory. Such interdisciplinary conceptual work is important because the prosperity and competitiveness of the EU depends not only on technological developments and commercial innovation, but also on the cultivation of stable, reflective and responsible governmental practices and public spheres. Project Aims: • Theoretical: To develop an interdisciplinary framework that clarifies the philosophical commitments behind studies of what Mark Warren calls ‘governance-driven democratization’. • Applied: This project will begin from and relate back to the wide range of policy innovations associated with ‘democratization’ of scientific governance in both the EU and North America. • Organisational: The project will develop mechanisms to transfer the knowledge and research networks acquired in the overseas phase to EU researchers across disciplines and sectors. Professor Mark Warren leads a global center of excellence in democracy studies at the University of British Columbia. I am uniquely placed to benefit from this fellowship in terms of skills and career development, to bring this project to successful and productive conclusion, and to benefit the EU through a clear plan for the dissemination of the knowledge and networks acquired during the projec;221678,58;221678,58;FP7-PEOPLE-IOF-2008;/MC-IOF;UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK;IE;;;"/COO;/EDU";1;0;0;2;0;0 95987;252618;ADAPTING2UNCERTAINTY;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IOF;FP7;Adaptive strategies for mate choice and aggression in the face of uncertainty;2010-06-01;2012-11-30;;BACKGROUND In interactive contexts (e.g. mate choice, aggression), individuals face a great deal of uncertainty over the behaviour of others. This makes decision-making difficult, because the best thing to do depends critically on the make-up of the social environment and the strategies others adopt. Current theory is poorly equipped to deal with these decisions because it typically assumes that individuals have perfect knowledge of the situation in which they find themselves, including the states of others with whom they interact. OBJECTIVES My project will investigate the evolution of behavioural strategies for dealing with uncertainty, focusing on aggression and mate choice. This will require an interdisciplinary approach, integrating economic concepts traditionally used in behavioural ecology with a more psychological perspective. STRATEGY To achieve this goal I will combine theory with empirical work and collaborate with world-leading researchers with the relevant expertise. In the outgoing phase, I will study aggressive behaviour in real animals to test novel predictions of my earlier models on uncertainty, running tests on captive zebra finches and examining patterns of aggression in data from humans. In the return phase, I will develop new models of mating behaviour that explicitly consider the uncertainty inherent in systems of mutual choice, using a Bayesian approach. RELEVANCE The project will considerably enhance my international, interdisciplinary research experience and train me specifically in the use of longitudinal databases for understanding behavioural development. With expert mentoring and a Personal Career Development Plan, this new knowledge and training will boost my professional development as an independent research scientist. At the same time, by testing key predictions from recent theory and developing new models of behaviour under uncertainty, the project has the potential to make an important contribution to EU scientific excellence.;199047,75;199047,75;FP7-PEOPLE-2009-IOF;/MC-IOF;UNIVERSITY OF BRISTOL;UK;;;"/LIF;/EDU";1;0;0;2;0;0 107839;330530;Changing Glaciers;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IIF;FP7;Changing Glaciers: Enhancing International Research Capacity and Learning Collaboration in Reconstructing the Impacts of Glacier Responses to Climate Change;2013-07-26;2014-07-25;;Climate change over both geological and human timescales has an immense impact on Earth environments. Changes in mountain glaciers provide both a particularly sensitive indicator of local-to-regional patterns of climate change and are crucial for water resources and natural hazards in mountainous regions and adjacent lowlands. An international research project, led by Professor Stroeven at Stockholm University, is focused on reconstructing changes in mountain glaciers across Central Asia. As a MCIIF, Professor Jon Harbor, a recognized senior leader in interdisciplinary research and education in glacial studies, will play a central role in this international research project. Professor Harbor will co-lead the fieldwork, be a primary collaborator in analyzing results and writing journal publications with faculty and students in member states and ICPCs, and will co-lead and evaluate collaborative online international educational modules involving students in the member states and the US. His work will enhance and reinforce research excellence in both the lead member state (Sweden), and five other member states and ICPCs (Germany, Kyrgyz Republic, Mongolia, Russia, and China). Professor Harbor’s unique areas of expertise for the MCIIF include terrestrial cosmogenic nuclide methods for glacial research, and development and evaluation of novel online collaborative learning. Outcomes of the MCIIF will include a significant broadening of the competences of the host and collaborating organisations, in particular in interdisciplinary expertise and in building long-term, mutually beneficial cooperation between Europe, the USA and Asian ICPCs.;137569,4;137569,4;FP7-PEOPLE-2012-IIF;/MC-IIF;STOCKHOLMS UNIVERSITET;SE;;;/SCI;1;0;0;2;0;0 103865;303031;POPREP;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IEF;FP7;Eurosceptic Populist Party Organization and Representation: A Comparative Study;2012-09-01;2014-08-31;;"'This proposal can be summed up under the following two headings 'Project' and 'Training'. While separate here for clarity, the conduct and success of each is essentially intertwined with - and dependent on - the other: (1) PROJECT: The project analyzes party organization and representation in six Eurosceptic populist parties: the Northern League (Italy), Sinn Féin (Ireland), the Swiss People's Party (Switzerland), Front National (France), the Danish People's Party (Denmark) and the Socialist Party (Netherlands). No comparative indepth study of this type, depth and breadth currently exists. The approach taken is conceptually innovative, methodologically interdisciplinary and theoretically ambitious. It answers calls for empirical research on populism by scholars and by the European Union itself (Work Programme, 2010). The research aims to provide the first comparative empirical study to date of Eurosceptic populist organization and representation, in a monograph with a top international publishing house, thus helping me achieve a leading independent academic position and an international profile as a key comparative European politics scholar. (2) TRAINING: Given the ambitions both of this project and my own career goals, high quality training in applied interdisciplinary methods, data analysis and project management are all essential prerequisites. With advice and support from renowned scholars and colleagues at the EUI, the overall aim of this fellowship is to build on my prior research career, but take it now to a far greater level of comparative and theoretical breadth, sophistication and originality thanks to the quality of mentorship, training and international research environment offered by the EUI. Through the skills acquired - and applied in the project - I will mature enormously as a scholar.'";193726,8;193726,8;FP7-PEOPLE-2011-IEF;/MC-IEF;EUROPEAN UNIVERSITY INSTITUTE;IT;;;/SCI;1;0;0;2;0;0 100847;283626;ARABCOMMAPH;ONG;FP7-IDEAS-ERC;ERC-SG-SH6;FP7;Arabic Commentaries on the Hippocratic Aphorisms;2012-02-01;2017-07-31;;"The Hippocratic Aphorisms have exerted a singular influence over generations of physicians both in the East and in the West. Galen (d. c. 216) produced an extensive commentary on this text, as did other medical authors writing in Greek, Latin, Arabic, and Hebrew. The Arabic tradition is particularly rich, with more than a dozen commentaries extant in over a hundred manuscripts. These Arabic commentaries did not merely contain scholastic debates, but constituted important venues for innovation and change. Moreover, they impacted on medical practice, as the Aphorisms were so popular that both doctors and their patients knew them by heart. Despite their importance for medical theory and practice, previous scholarship on them has barely scratched the surface. Put succinctly, the present project breaks new ground by conducting an in-depth study of this tradition through a highly innovative methodology: it approaches the available evidence as a corpus, to be constituted electronically, and to be analysed in an interdisciplinary way. We propose to survey the manuscript tradition of the Arabic commentaries on the Hippocratic Aphorisms, beginning with ?unayn ibn ?Is??q’s Arabic translation of Galen’s commentary. On the basis of this philological survey that will employ a new approach to stemmatics, we shall produce provisional electronic XML editions of the commentaries. These texts will constitute the corpus, some 600,000 words long, that we shall investigate through the latest IT tools to address a set of interdisciplinary problems: textual criticism of the Greek sources; Graeco-Arabic translation technique; methods of quotation; hermeneutic procedures; development of medical theory; medical practice; and social history of medicine. Both in approach and scope, the project will bring about a paradigm shift in our study of exegetical cultures in Arabic, and the role that commentaries played in the transmission and transformation of scientific knowledge.";1499968;1499968;ERC-2011-StG_20101124;/ERC-SG;THE UNIVERSITY OF MANCHESTER;UK;THE UNIVERSITY OF WARWICK;UK;"/SCI;/SOC";1;0;0;2;0;0 108034;318982;SPRINGARAB;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IRSES;FP7;Social movements and mobilisation typologies in the arab spring;2013-02-28;2016-06-27;;"The present proposal aims to revitalize and to reinforce the Europe-Arab World exchange in the field of research and training in Social Sciences, during a peculiar historical moment, characterized by the socio-political changes that have taken place in the last year in the Southern Mediterranean Arabic societies. Paying attention to the new context, the proposal will especially focus research on social and political movements in the frame of change dynamics and applying a comparative approach, taking particularly into account the experience of Eastern European countries. The proposal objectives are to contribute to the enrichment of the analytical interpretation and to the monitoring of the social, political ans cultural processes that have taken and are taking place in the arabic World, through the collection of new empirical materials and the development of innovative analytical tools from different disciplines (political science, sociology, anthropology, cultural studies, religious studies, media) in an interdisciplinary and comparative approach. These tools will be developped through the active participation of early researchers in the implementation of the proposal, articulating fields surveys and conceptual appoach: structuring exchanges through interdisciplinary training sessions to be followed by mixed groups of junior researchers from the Arab and European universities; implementing a joint doctoral program; organizing conferences, workshops and managerial meetings in different universities of Europe and Maghreb. Consequently, the outcomes of the proposal will contribute to the ongoing international academic and political debate on social and political change to reach a best governance. It will also contribute to bring fresh knowledge in the study of concepts and theories concerning political mobilisation, social movements, youth movements; democracy, citizenship, identity policy. Finaly the proposal will support critical and autonomous social sciences";879700;879700;FP7-PEOPLE-2012-IRSES;/MC-IRSES;UNIVERSITE PARIS 8 VINCENNES SAINT-DENIS;FR;"UNIVERSITAT ROVIRA I VIRGILI;UNIVERSITA DEGLI STUDI DI FIRENZE;UNIWERSYTET JAGIELLONSKI";"ES;IT;PL";/SCI;1;0;0;2;0;0 101173;295152;NH-MCDM;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IRSES;FP7;New Horizons for Multi Criteria Decision Making;2012-01-01;2015-12-31;;"Complex problems usually require the simultaneous consideration of multiple performance criteria within multidisciplinary environments. Multi-objective optimization (MOO) and, especially, evolutionary multi-objective optimization (EMO), is now recognized as possessing the potential to have a major impact in such problems. This is evidenced by the rapidly growing number of research publications and by the availability of a number of related software tools and users (academia and industry). As part of this development, Multi Criteria Decision Making (MCDM), based on the results obtained through EMO/MOO, is an important challenge. The Consortium suggested here, has identified a number of very novel research directions within EMO/MOO, which promise a major step-change in the way that decision-making in complex interdisciplinary problems may be successfully realised. These directions not only will attract the research community but will also enhance its uptake by industry and other businesses. The Consortium consists of an interdisciplinary group of EMO pioneers and world-class researchers together with enthusiastic early-career researchers who are excited by this research field and it's potential. The Consortium, possess remarkable complementarity with regard to theoretical and practical aspects of the research, and the fact that some pairings have already generated important results reinforces our conviction that Consortium research will make outstanding contributions to the field of MCDM. Our research will be underpinned by a strong programme of knowledge exchange, involving such activities as seminars, workshops, demonstrators and e-learning tools, aimed at both research institutions, industry and related businesses. The Consortium will strive to enhance science by providing a supporting environment for experienced as well as early stage researchers. This will be realised through the free exchange of knowledge across organizations, nations and continents.";287700;287700;FP7-PEOPLE-2011-IRSES;/MC-IRSES;ORT BRAUDE COLLEGE;IL;THE UNIVERSITY OF SHEFFIELD;UK;/SCI;1;0;0;2;0;0 101600;284995;SMART-NEST;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IAPP;FP7;Smart Technologies for Transport Safety - Innovation Cluster Nesting;2012-01-01;2015-12-31;http://smart.ippt.pan.pl/smart-nest/;"The main objective of the proposed project is to establish a European-level vibrant training environment in a rapidly emerging research field at the crossroads of structural engineering and smart technologies. The participants link up their cross-sectoral expertise to support their researchers in pursuing an interdisciplinary career and to provide them with a cohesive training environment. The proposed project: --- in terms of the end product investigates, designs and develops a new class of semi-actively controlled smart structures, which are impact- or vibration-resistant, capable of preserving integrity in critical conditions under unpredictable loads and of post-accident self-diagnosis; --- in terms of the methodology, aims at investigating new, semi-active strategies for optimum structural adaptation, which requires exploring techniques for system identification, model updating and load identification; --- in terms of the technology, explores and applies promising smart technologies for (i) semi-active structural control and adaptation and (ii) robust self-diagnosis. Strong interdisciplinarity of the research and training programme is implied by the need for integration and implementation of knowledge, techniques and technologies scattered among various disciplines. The project is based on in-depth studies in system identification and model updating, proceeds to identification of dynamic loads, a prerequisite for optimum strategies for semi-active structural adaptation to unknowns loads. In parallel, relevant smart sensors/actuators, driving electronics and self-diagnosis techniques will be pursued. Finally, respective hardware and model demonstrators will be implemented and evaluated. An important intended effect is fostering inter-sectoral Academia-Industry skills and mobility of the involved researchers. This will lead to a cross-sectoral transfer of knowledge between the participant institutions and increase their success prospects in both sectors.";1755362;1755362;FP7-PEOPLE-2011-IAPP;/MC-IAPP;INSTYTUT PODSTAWOWYCH PROBLEMOW TECHNIKI POLSKIEJ AKADEMII NAUK;PL;"CEDRAT TECHNOLOGIES SA;ECOLE CENTRALE DE LYON;I-Deal Technologies GmbH;ADAPTRONICA ZOO SP;UNIVERSITAT DES SAARLANDES";"FR;DE;PL";/IND;1;0;0;2;0;0 87751;210934;19TH-CENTURY_EUCLID;ONG;FP7-IDEAS-ERC;ERC-SG-SH4;FP7;Nineteenth-Century Euclid: Geometry and the Literary Imagination from Wordsworth to Wells;2009-01-01;2011-10-31;;This radically interdisciplinary project aims to bring a substantially new field of research – literature and mathematics studies – to prominence as a tool for investigating the culture of nineteenth-century Britain. It will result in three kinds of outcome: a monograph, two interdisciplinary and international colloquia, and a collection of essays. The project focuses on Euclidean geometry as a key element of nineteenth-century literary and scientific culture, showing that it was part of the shared knowledge flowing through elite and popular Romantic and Victorian writing, and figuring notably in the work of very many of the century’s best-known writers. Despite its traditional cultural prestige and educational centrality, geometry has been almost wholly neglected by literary history. This project shows how literature and mathematics studies can draw a new map of nineteenth-century British culture, revitalising our understanding of the Romantic and Victorian imagination through its writing about geometry.;323118;323118;ERC-2007-StG;/ERC-SG;UNIVERSITY OF GLASGOW;UK;;;/SOC;1;0;0;2;0;0 89111;232997;TICE;ONG;FP7-IDEAS-ERC;ERC-AG-LS7;FP7;TRANSCRIPTOMICS IN CANCER EPIDEMIOLOGY;2009-01-01;2014-06-30;;NOWAC is the first prospective study with a globolomic design. This is an extension of the current cohort study with its questionnaire information and biological material for analysis of biomarkers, proteomics and single nucleotide polymorphisms (SNPs). The design of NOWAC adds biological material for analysis of the transcriptome in prospectively collected buffered peripheral blood samples, the postgenome biobank. Further, both peripheral blood and tumor tissue are collected from breast cancer patients diagnosed within the cohort together with matched controls. The latter biological material gives a new multidimensional design with a unique biological material at the end-point. The transcriptomic analysis will include both mRNA and miRNA as new technology (microarray and massive parallel sequencing) allows large scale studies. miRNAs could be promising markers for pathways analysis related to the carcinogenic process and for diagnosis and screening tests of breast cancer. These high-troughput technologies have analyses challenges both in bioinformatics and biostatistics therefore success depends on the development of new analytical strategies.This novel design is the observational counterpart to systems biology, or systems epidemiology. Systems epidemiology will seek to understand biological processes by integrating observational derived pathways information into the current prospective design. A true interdisciplinary approach has been implemented. The upside is the potential for an improved understanding of causality in epidemiology by opening up for quantification of traditional criteria of biological plausibility in a more complete biological model. The postgenome biobank with 50 000 participants out of the 172 000 participants in NOWAC and its unique national design and richness of biological material makes it a very strong case for interdisciplinary collaboration based on a population-based study representative of the real and complex lifestyle environment.;2428965,73;2300000;ERC-2008-AdG;/ERC-AG;UNIVERSITETET I TROMSOE;NO;;;"/HCS;/LIF;/MED";1;0;0;2;0;0 92714;240891;EMOTER;ONG;FP7-IDEAS-ERC;ERC-SG-SH4;FP7;Emoting the Embodied Mind;2010-01-01;2014-12-31;;This project aims to develop a theoretical account of the mind that acknowledges its embodied as well as emotional character, thus cutting across traditional dichotomies such as head/body, reason/passion, intellect/instinct, and nurture/nature. This goal involves bringing together two research fields that have paid relatively little attention to each other the embodied approach in the philosophy of mind and cognitive science, and the emerging field of affective science . Both fields have undergone considerable developments in the last years, and both represent thriving interdisciplinary research areas. The proposed framework will detail the various ways in which the embodied and emotional features of the mind relate to one another, including the implications that an embodied-emotional view of the mind will have for our concepts of consciousness, value, and rationality. The project is divided into four interrelated yet distinct self-contained subprojects that will be completed over a period of five years. Subproject 1 will address the question of the nature of emotion experience and its relation to the body through an analysis of accounts of lived experience found in philosophical phenomenology, psychology and neuroscience. Subproject 2 will discuss the possibility to extend emotions beyond the boundary of the organism. Subproject 3 will develop an embodied account of value, from simple to more complex organisms. Subproject 4 will elaborate the implications of an embodied-emotional view of the mind for philosophical conceptions of control, rationality, and normativity. Overall, these themes outline a project which is philosophical in its aims (the development of a theoretical framework, and the philosophical implications of such a framework), and interdisciplinary in its methodology. Part of it will in fact examine and discuss various psychological and neuroscientific studies in detail, and recommend new avenues for empirical research in these disciplines.;685301;685301;ERC-2009-StG;/ERC-SG;THE UNIVERSITY OF EXETER;UK;;;/SOC;1;0;0;2;0;0 92700;235886;ADHCEM;ONG;FP7-PEOPLE;FP7-PEOPLE-IIF-2008;FP7;ADHESION AS A TOOL FOR IN-BUILT NANOTECHNOLOGY IN CEMENT-BASED MATERIALS;2010-01-01;2011-12-31;;The global cement industry produces 2.8 billion tones of product plus 1bn tones of CO2 and is increasing at 5% per annum, especially in developing nations. This is one of the largest CO2 producing industries which needs to improve the efficiency of its product to reduce global impact. Yet the understanding of the fundamental binding forces in cement is not clear. This project aims to study the nano-scale forces operating between the cement gel particles in order to produce more effective cement products, provided there is much of interest in linking phenomena occurring at the nano-scale with engineering performance at the macro-scale. The fellow’s expertise on the forces involved between nanoparticles with structured water on their surface will give an important insight in how to use the adhesive potential of water in cement-based materials. This should allow the designing of suitable cementitious microstructures containing nanometric particles, at present a very difficult task. Indeed, this is the first time that these interdisciplinary ideas of adhesion by confined water will be systematically explored in cement-based materials, including those used as biomaterials. To do so, this project will bring together the interdisciplinary concepts and techniques from nanoscience with examples from bioadhesion to define radical changes and applications. Ultimately, this project is timely and relevant because the European leading companies (cement-based service providers or manufacturers – four out of the world top five cement producers are European) are being pushed to offer sustainable materials as well as best mechanically tailored ones. The scientific benefit will be defined by the high quality papers submitted to leading academic adhesion and nanoscience journals. In turn, societal benefit will be gained by exporting the results to emerging countries where the economic development model needs urgently to respect the sustainability.;;181350,76;FP7-PEOPLE-IIF-2008;/MC-IIF;THE UNIVERSITY OF BIRMINGHAM;UK;;;"/SCI;/EMP";1;0;0;2;0;0 95840;254671;SMAT;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IEF;FP7;Structure and function of SMAT: a putative cellular decision-maker for transcription factor assembly;2010-04-01;2012-03-31;;Transcription factor IID (TFIID) is a key player in regulated transcription of eukaryotic genes by RNA polymerase II. The scaffold of TFIID is composed of a number of TATA-box binding protein-associated factors (TAFs), which are also found in other multimeric transcription factors (e.g. SAGA). An elaborate system of decision-making therefore must occur that directs the assembly of TAFs into either TFIID or SAGA or other TAF containing complexes. Recently, a multimeric 400 kDa small TAF-containing complex, SMAT, was discovered. SMAT is proposed to be a potent regulator of committed TFIID and SAGA assembly. The objective of this proposal is to elucidate the role of SMAT in eukaryotic gene regulation by means of an integrated, interdisciplinary approach combining structural, biochemical and in vivo cell biology methods. SMAT and its subcomplexes will be produced recombinantly by state-of-the-art eukaryotic expression techniques. Stable variants of SMAT core-complexes will be identified by a novel limited proteolysis/mass spectrometric approach and translated into expression experiments by utilizing an automated cloning platform technology. Intensive screening for growth of single, well diffracting crystals will be performed at the high-throughput crystallization facility at EMBL. By combining synchrotron X-ray crystallography, electron microscopy and small angle X-ray scattering experiments, a molecular model of SMAT will be obtained. Based on this model, point mutations will be designed, which specifically destabilize SMAT. Effects of the mutant proteins and of posttranslational modifications on the cellular decision-making process of TFIID or SAGA assembly, as well as SMAT integrity, will be assessed by in vivo functional assays in HeLa cells. The interdisciplinary nature of this project promises to contribute to the applicant’s career development by diversifying his competences and refining his skills ultimately guiding him towards an independent leading position.;165645,6;165645,6;FP7-PEOPLE-2009-IEF;/MC-IEF;EUROPEAN MOLECULAR BIOLOGY LABORATORY;DE;;;"/SCI;/EDU;/ITT";1;0;0;2;0;0 88248;205509;BIOCERENG;ONG;FP7-IDEAS-ERC;ERC-SG-PE6;FP7;Bioceramics: Multiscale Engineering of Advanced Ceramics at the Biology Interface;2009-01-01;2013-12-31;;In the last decades, Materials Sciences and Life Sciences, two highly dynamically evolving and interdisciplinary research areas, have been influencing natural and engineering sciences significantly, creating new challenges and opportunities. A prime example for an increasing synergetic overlap of Materials and Life Sciences is provided by biomedical and bioengineering applications, which are of great academic, but also of steadily increasing societal and commercial interest. Bridging the traditional borders of disciplinary thinking in these areas has become one of today’s most challenging tasks for scientists. One group of key materials that are of great importance to biomedical engineering and bioengineering are advanced oxide and non-oxide ceramics with specific functionalities towards biological environments, so-called Bioceramics. The interplay at the interface of ceramics-protein-cells/bacteria is very complex and requires multiscale and interdisciplinary approaches. This expertise, that is under continuous development in my Bioceramics group, encompasses materials processing, shaping, surface functionalisation and cells/bacteria evaluation at the same time. The comprehensive research environment and expertise provides a unique opportunity to engineer materials/surfaces with immediate subsequent biological evaluation in order to achieve an extremely short development time. A centre of focus is the contribution of electrostatic and hydrophilic/hydrophobic interactions to the overall biocompatibility and -activity. The proposed research project includes four closely interrelated subprojects, addressing the following topics: “Interaction of surface functionalised ceramic particles with proteins”, “Cytotoxicity of functionalised oxide particles”, “Fabrication and testing of functionalised porous Al2O3 as filters for water cleaning and bioengineering applications” and “Novel functional scaffold composites for bone tissue engineering”.;1536120;1536120;ERC-2007-StG;/ERC-SG;UNIVERSITAET BREMEN;DE;;;"/PSE;/IPS";1;0;0;2;0;0 95358;253090;CLIMATEGOV;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IEF;FP7;Managing Interactions between International Agreements: Dealing with Diversity in Global Climate Governance;2010-06-07;2011-12-06;;"The proposal seeks to support the career development of an experienced researcher, by completing an interdisciplinary research project on dealing with interactions in global climate governance, and enabling the fellow to acquire new knowledge and academic skills at a renowned university. The scientific objectives of the research are to analyse how the diversity in global climate governance, and interactions between different international agreements have affected the normative development of these agreements; to assess legal techniques and political mechanisms for dealing with the diversity in global climate governance; and to provide policy and research recommendations, and disseminate the findings of the research project. Three cases are used to illustrate the interactions, and to assess the legal and political options to manage interactions. These cases allow for a comprehensive analysis of the various forms of fragmentation in global climate governance, while at the same time providing broader insights for other areas of international law and global governance studies. The host institution for the fellow is the Environmental Change Institute (ECI) at the University of Oxford. ECI hosts many experienced scholars relevant to the proposed research, and has an excellent reputation in interdisciplinary climate change research. The Institute also has an outstanding track record of training researchers. The research training objectives are to contribute to the fellow’s writing and publication skills, through significant progress in completing his doctoral thesis and the publication of peer-reviewed articles; to enhance the fellow’s knowledge on interactions in global environmental governance; to participate in postgraduate courses, lectures, seminars and other events held at the University of Oxford; and to collaborate and interact with scholars at ECI on research areas of mutual interest.";124030,6;124030,6;FP7-PEOPLE-2009-IEF;/MC-IEF;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;UK;;;"/SCI;/EDU;/ITT";1;0;0;2;0;0 88284;215414;WAVETRAIN 2;ONG;FP7-PEOPLE;PEOPLE-2007-1-1-ITN;FP7;Initial Training Network for Wave Energy Research Professionals;2008-10-01;2012-06-30;;"The proposed action builds strongly up on the logics of its predecessor with the same name. The overall objective is to create a pool of specialised wave energy research professionals to support an emerging industry in a field with a very strong anticipated growth and no dedicated existing training curriculum. Although most jobs can be done being a trained engineer in one of the adjacent fields, the existance of interdisciplinary skilled researchers trained in direct connection to the technology development is vital for successful development. In the predecessor, almost all fellows where immediatley absorbed by industrial players in the field or continued research in the host institution. The work plan for WAVETRAIN 2 fellows is specifically directed towards a wide range of challenges that industrial-scale wave energy implementation faces in the present situation, with some bias towards technical issues, from hydrodynamic and PTO (Power-Take-Off) design, to instrumentation issues and energy storage and cost reduction show to be critical for successful deployment. On the other hand, also non-technical “barriers”, typically less tangible difficulties related to legal issues (licensing, conflicts of use, EIA procedures, grid connection, regional differences) and the non-sufficient representation of socio-economic benefits of the sector, will be dealt with, as they are seen as a major obstacel for fast implementation on a European scale. The methodology to achieve the desired results is to provide (i) in-depth training in one applied research topic (host institution), (ii) good interdisciplinary background and understanding of industry environment (short courses and secondments), and (iii) active participation in wave power plant testing in the sea (some of the profiles; others: site visits). The in-depth training at the host institution will be incorporated in relevant research topics, where typically an advance the state-of-the-art is expected.";3579635;3579635;FP7-PEOPLE-2007-1-1-ITN;/MC-ITN;WAVEC/OFFSHORE RENEWABLES - CENTRO DE ENERGIA OFFSHORE ASSOCIACAO;PT;"SPOK APS;FUNDACION TECNALIA RESEARCH & INNOVATION;ECOLE CENTRALE DE NANTES;Wave Dragon Ltd;THE QUEEN'S UNIVERSITY OF BELFAST;AWS OCEAN ENERGY LTD;NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU;UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK;AALBORG UNIVERSITET;THE UNIVERSITY OF EDINBURGH;INSTITUTO SUPERIOR TECNICO;TECHNISCHE UNIVERSITEIT DELFT";"DK;ES;FR;UK;NO;IE;PT;NL";"/EMP;/SOC;/EDU";1;0;0;2;0;0 100229;288734;SMARD;CLO;FP7-ICT;ICT-2011.1.5;FP7;European Support Framework on Networked Media R&D for SMEs;2011-09-01;2013-03-31;;The EU-Project SMARD - European Support Framework on networked Media R&D for SMEs - has been designed to fill the existing gap within the exploitation chain between successful Networked Media Research and the commercialisation by SMEs.
The SMARD Consortium is led by MFG Baden-Württemberg and comprises European partners from Salzburg Region (Salzburg Research), Flanders (Interdisciplinary Institute for Broadband Technology (IBBT) and Piemonte (CSP innovazione nelle ICT).
The vision is to put advanced digital media technologies in the focus of future markets for SMEs from the digital media industries as well as web-economy and beyond. Therefore the project tackles two core questions: On the one hand the degree of the responsiveness of FP7 projects to SME needs and requirements and on the other hand on the needs of R&D at the stage for successful market introduction. The project aims to identify fields of action and to develop hands on processes and service packages for Networked Media R&D commercialization.
A Survey with at least 400 SMEs from all over Europe on needs of SMEs in the Digital Media industries and web economy regarding Networked Media R&D and an analysis of FP7 projects reading their responsiveness to SME needs and requirements will be conducted. The project will deliver approaches for practitioners in the field of technology transfer, summarized in a guideline.Recommendations towards a future European support framework for Networked Media R&D will reflect valuable lessons from the SMARD project.
SMARD puts a particular focus on ensuring sustainability and European impact of the project through targeted involvement of regional and international stakeholders throughout the project duration.;603296;551000;FP7-ICT-2011-7;/CSA;MGF MEDIEN-UND FILMGESELLSCHAFT BADEN-WUERTTEMBERG MBH;DE;"CSP INNOVAZIONE NELLE ICT SCARL;SALZBURG RESEARCH FORSCHUNGSGESELLSCHAFT M.B.H.;IMINDS";"IT;AT;BE";/INF;1;0;0;1;0;0 96844;254889;EUROTEXTBOOKSCIENCE;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IEF;FP7;The Rise and Fall of Textbook Science: Technoscientific and Pedagogical Expertise in the Making of Physics in Europe (1802-1902);2010-12-01;2012-11-30;;"This project is a history of the making of physics as a discipline in Europe, built upon a multidisciplinary and cross-national analysis of the status of the physics textbook in education and research. The project spans the period between the pioneering establishment of secondary education in France (1802), and the simultaneous implementation of major educational reforms in France, Britain and Spain (1902), with repercussions lasting to the present day. Current knowledge suggests that textbooks had a major role in the establishment of science education, and the making of disciplines such as physics. However, their status and characteristics changed over time, in tune with dramatic changes in pedagogical and research practices. This project addresses this question through an approach which is innovative on four major grounds: a) Internationality, b) Interdisciplinary approach, c) Textbook and Pedagogy focus, d) Attention to the Material Culture of science and education. By means of six case-studies focused on the work of six major teachers and textbook authors, this project studies the production, distribution and use of physics textbooks and their changing status, through four combined aims: Mapping the pedagogical cultures of physics, and establishing the role of textbooks, the book trade and instrument making, respectively, in the making of physics as a discipline in Europe. Through synchronic and diachronic analysis, this project seeks to yield strong results in global perspective. Its objectives are to produce: 1) A new history of the emergence of physics in Europe based on an original approach and innovative focus. 2) A major contribution to the boost of the study of science pedagogy within history of science, history of education and book history, through the publication of a monograph on "Writing the History of Nineteenth-Century Science Education". 3) A strong historical case able to inform reflection on the design of current science & education policy.";158945,6;158945,6;FP7-PEOPLE-2009-IEF;/MC-IEF;UNIVERSITE PARIS NANTERRE;FR;;;"/SCI;/EDU;/ITT";1;0;0;1;0;0 87288;221560;DEMOS-ACT;ONG;FP7-PEOPLE;PEOPLE-2007-2-1.IEF;FP7;Democratic Innovations and Citizens in the EU;2008-04-01;2009-03-31;;Representative democracies are currently challenged by an increasing decline of political satisfaction and trust. Many European governments have tested diverse democratic innovations with the aim of enhancing political contentment as well as increasing citizens’ understanding of political matters. However, do democratic innovations, for example direct democracy or deliberative procedures, fulfil the hopes? This question remains unanswered, because currently no comprehensive data pool, no theoretical framework, and no systematic evaluation of democratic innovations in Europe exist. The applying fellow, Brigitte Geissel, and the applying institution, the Interdisciplinary Centre of Excellence “Democracy: A Citizen Perspective” at ?bo Akademi University (Finland), will address this gap and meet the demand of political scientists and politicians alike for valid expertise regarding the advantages and disadvantages of democratic innovations. The objectives of the research project are, in short, (1) to pool the theoretical and empirical knowledge on different innovations, (2) to develop a theoretical framework with criteria for the evaluation of democratic innovations, and (3) to explore the advantages and disadvantages of democratic innovations by secondary analysis in comparative perspective. The project will focus on democratic innovations in European states, with an emphasis on the Nordic countries, which are especially advanced in that field. The objectives of the applicant are to develop further professional, methodological and management skills, to establish international research networks, especially with the Nordic countries, and to open up as well as to establish a new research topic.;116611,34;116611,34;FP7-PEOPLE-2007-2-1-IEF;/MC-IEF;ABO AKADEMI;FI;;;"/SCI;/EDU";1;0;0;1;0;0 95605;242212;DORIS;ONG;FP7-SPACE;SPA.2009.1.1.01;FP7;Ground Deformations Risk Scenarios: an Advanced Assessment Service;2010-10-01;2013-09-30;http://www.doris-project.eu/;"DORIS is an advanced downstream service for the detection, mapping, monitoring and forecasting of ground deformations, that integrates traditional and innovative Earth Observation (EO) and ground based (non-EO) data and technologies. The service delivers innovative products tailored for Civil Defense authorities. DORIS integrates state-of-the-art technological and scientific capabilities with existing European upstream services, complies with guidelines provided by the Emergency Response Core Services Interdisciplinary Group, and is linked to existing Core Services, including SAFER and GMES EMERGENCY. DORIS goes beyond the state-of-the-art technologies used to detect, map, monitor and forecast ground deformations. DORIS uses the unique ERS-1/2 and ENVISAT C-band SAR archives to provide unprecedented, very long time-series of ground deformations. DORIS evaluates new SAR sensors, including ALOS, COSMO-SkyMed and TERRASAR-X, exploiting the different bands (L/X), the significantly reduced revisiting time, and the higher spatial resolution offered by these sensors. DORIS moves forward the integration of satellite and ground-based SAR interferometry, coupled with GPS measurements and geophysical probing. DORIS exploits multi-spectral images to map ground deformations, to identify the elements at risk, and for dynamic risk scenarios design. Finally, DORIS investigates the possibility of using thermal images for the assessment of landslide susceptibility and hazard. DORIS will be tested in six study areas in Europe. Successful application of the service in these areas guarantees that the downstream service will work in Europe. DORIS will provide a business model for long term self-sustainability of the service; the project is proposed by a unique team of public administrations, research institutes, and enterprises with experience in EO technologies for Civil Defence applications. DORIS favors knowledge and technology transfer, and will stimulate European competitiveness.";4710404,12;3395865,98;FP7-SPACE-2009-1;/CP;CONSIGLIO NAZIONALE DELLE RICERCHE;IT;"TRE ALTAMIRA SLU;PRESIDENZA DEL CONSIGLIO DEI MINISTRI - DIPARTIMENTO DELLA PROTEZIONE CIVILE;AGENZIA SPAZIALE ITALIANA;FEDERAL DEPARTMENT FOR ENVIRONMENT TRANSPORTS ENERGY AND COMMUNICATION;GAMMA REMOTE SENSING RESEARCH AND CONSULTING AG;UNIVERSITA DEGLI STUDI DI FIRENZE;Tele-Rilevamento Europa - T.R.E. s.r.l.;BOOZ & COMPANY BV;MAGYAR FOLDTANI ES GEOFIZIKAI INTEZET;INSTITUTO GEOLÓGICO Y MINERO DE ESPA?A;PANSTWOWY INSTYTUT GEOLOGICZNY - PANSTWOWY INSTYTUT BADAWCZY;BOOZ & COMPANY GMBH;Tecnologie per le Osservazioni della Terra ed i Rischi Naturali";"ES;IT;CH;NL;HU;PL;DE";/SPA;1;0;0;1;0;0 96164;270525;LIN10;ONG;FP7-SIS;SiS;FP7;60th Nobel Laureate Meeting at Lindau - Interdiscinplinarity, Internationalisation, and Excellence;2010-05-01;2011-04-30;;"Since 1951, Nobel Laureates meet in Lindau during the summer for a week of open-minded exchange, exploration of new horizons and connecting to the world’s most promising young academic researchers. In 2010, the 60th Nobel Laureate Meeting will take place from June 27th to July 2nd at Lake Constance, bringing together Laureates and Best Talents from all disciplines in natural sciences. This 3rd Interdisciplinary Meeting (after 2000 and 2005) will connect, inspire and educate almost 70 Laureates and over 650 young researchers. Based on a globally unique approach, this international forum of excellence perfectly embodies the four goals of the 7th Framework Programme: • To gain leadership in key scientific and technology areas • To stimulate the creativity and excellence of European research • To develop and strengthen the human potential of European research • To enhance research and innovation capacity throughout Europe In combination with its outreach activities such as the exhibition on the Isle of Mainau “Discoveries: Energy”, focusing on the topics of environment and sustainability, the Tiny Tots Center and the Mediatheque with scientific lectures from six generations, the Lindau meetings serve as one of the most successful brain gain initiatives for Europe.";2283000;55000;FP7-Adhoc-2007-13;/CSA-SA;Foundation Lindau Nobelprizewinners Meetings at Lake Constance;DE;;;"/SCI;/SOC";1;0;0;1;0;0 99469;275214;Mapping the mind;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-IOF;FP7;The psychological construction of mental states: How the mind is realized by distributed networks in the brain;2011-08-01;2014-01-31;;Psychology studies the mind by investigating the basic processes that underlie experiences such as ‘thinking’, ‘feeling’ and ‘perceiving’. The dominant approach presumes that these mental states can be distinguished into separate psychological processes (e.g. ‘cognition’, ‘emotion’, ‘perception’) supported by functionally specific areas in the brain. The present proposal takes an innovative stance on how the brain creates the mind by proposing that mental states are constructed out of a common set of basic psychological ingredients associated with distributed networks in the brain. We hypothesize that all mental states, including emotional states (e.g. anger or fear) and cognitive states (e.g. a state of concentration or an experience of beauty), are ‘constructed’ out of a pantry of basic ingredients. The present proposal will investigate how the brain realizes mental states in two imaging experiments. In the outgoing phase we will investigate the active brain networks that underlie the construction of mental states following the manipulation of interoceptive sensations. This phase will consist of a visit to the Interdisciplinary Affective Science Laboratory located at Northeastern University, Boston, United States. During this phase the applicant will receive excellent training in functional brain imaging techniques at the Martinos Center for Biomedical Imaging. The knowledge and experience that is obtained in this phase will be implemented in a second imaging experiment that will investigate the active brain networks that underlie the construction of mental states following the manipulation of exteroceptive sensations. This experiment will be executed at the Department of Social Psychology at the University of Amsterdam (UvA), The Netherlands. The present project will contribute to the ambitions of the UvA to become one of the leading imaging centers in Europe, and to the career goals of the applicant to become a successful neuroimaging scientist.;192471,4;192471,4;FP7-PEOPLE-2010-IOF;/MC-IOF;UNIVERSITEIT VAN AMSTERDAM;NL;;;"/EMP;/SOC;/COO";1;0;0;1;0;0 90883;235123;GALAPAGOS;ONG;FP7-PEOPLE;FP7-PEOPLE-IEF-2008;FP7;Cophylogeography of ecological replicates: the coevolution and biogeography of Galapagos mockingbirds and their ectoparasites;2009-06-08;2011-05-07;;Evolutionary radiations of colonists on archipelagos provide valuable insight into the mechanisms and modes of speciation. Using both morphological and molecular genetic techniques this study will examine the coevolutionary history of multiple ectoparasite lineages parasitizing the endemic mockingbirds of the Galapagos. Using 3000\ samples collected by a recent EU funded project this study will compare and contrast the genetic structure of mockingbird ectoparasites at six different scales (between and within host species, islands, and parasite groups) for the parasitic lice and mites infecting mockingbirds on the 16 islands of the Galapagos. Each widespread parasite lineage forms an ecological replicate to test the relative contributions of host diversification and geography to patterns of parasite genetic differentiation and speciation. This system provides a framework to understand the correlates of parasite diversification, their mode of speciation and the evolution of host specialization. These data will make an important contribution to our understanding of how louse-vectored diseases may be spread, and help inform conservation plans due to the higher rates of genetic evolution in parasite groups, relative to their avian hosts. The region is a UNESCO World Heritage Site and Biosphere Reserve, and the host group played a now famous role in triggering Charles Darwin’s initial insights into natural selection. Key outputs include a genetic study of the parasite lineages, biogeographic and coevolutionary analyses of the host-parasite relationships, and a database of host-parasite associations, images, and related data. These will be collated on a project website using an EU funded EDIT “Scratchpad”. Interdisciplinary training in molecular and morphological systematics and biodiversity informatics will be provided by the project coordinator, coupled with a structured postdoctoral course run by the host institution to develop the applicant’s transferable skills.;;173416,47;FP7-PEOPLE-IEF-2008;/MC-IEF;NATURAL HISTORY MUSEUM;UK;;;"/SCI;/EMP";1;0;0;1;0;0 101721;295345;EURAXESS T.O.P II;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-EURAXESS-II;FP7;Enhancing The Outreach and Effectiveness of the EURAXESS Network Partners. EURAXESS T.O.P II;2012-01-01;2014-12-31;;"Advanced research and knowledge-based innovation are keys to develop sustainable and globally competitive high-tech industry in high-cost Europe. Early access to front-line research results demands recruitment of, and collaboration between, world-class researchers. Reduction of legal and practical barriers to transnational mobility is then imperative. Interdisciplinary, intersectorial and geographical mobility must be facilitated by providing key practical information and qualified hands-on assistance to mobile researchers within a European Research Area (ERA) open to the world – in line with the Lisbon Agenda (2000), the Researchers’ Charter & Code (2005), Scientific VISA (2005), the ERA Green Paper (2007), the Ljubljana process (2008), the Europe 2020 Strategy (2009), the Europe 2020 Flagship Initiative – Innovation Union (2010), and the process towards the new Common Strategic Framework (2011). The EURAXESS network is a pan-European initiative in 37 countries with national web portals and over 200 Service Centers (ESCs) and Local Contact Points (LoCPs) at research institutions, established to facilitate researcher mobility by providing key practical information and qualified hands-on assistance to mobile researchers. In EURAXESS TOP2, which builds from EURAXESS TOP and other related EU- projects, key people from 17 Partners and 13 Associate Partners join forces to enhance the overall performance, quality, effectiveness and coherence of the information and services delivered by the network by exchange of best practices achieved over the years, training sessions and updating of portals. The interlinked Work Packages and Tasks include Charter & Code, Social Security & Pensions, Open Recruitment, Industry/Innovation, Skills, Portals, Capacity Building, Electronic Handbook updating, Promotion, and Strategic Dialogue with key stakeholders. Expected impacts: improved services \ enhanced recruitment and mobility of researchers.";3488799,6;2999983;FP7-PEOPLE-2011-EURAXESS-II;/CSA-CA;FUNDACION ESPANOLA PARA LA CIENCIA Y LA TECNOLOGIA;ES;"CONFERENCE DES PRESIDENTS D'UNIVERSITE;SIHTASUTUS EESTI TEADUSAGENTUUR;TUDOMANYOS ES TECHNOLOGIAI ALAPITVANY;ETHNIKO KENTRO EREVNAS KAI TECHNOLOGIKIS ANAPTYXIS;MACEDONIAN ACADEMY OF SCIENCES AND ARTS;THE BRITISH COUNCIL;BAY ZOLTAN ALKALMAZOTT KUTATASI KOZHASZNU NONPROFIT KFT.;STREDISKO SPOLECNYCH CINNOSTI AV CR v.v.i.;MASINSKI FAKULTET - UNIVERZITETA U NISU;INSTITUTE OF TECHNOLOGY AND DEVELOPMENT FOUNDATION;IRISH UNIVERSITIES ASSOCIATION;BAR ILAN UNIVERSITY;SAIA, n. o.;NORGES FORSKNINGSRAD;EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH;FONDAZIONE CRUI PER LE UNIVERSITA ITALIANE;AGENCIJA ZA MOBILNOST I PROGRAME EUROPSKE UNIJE;SIHTASUTUS ARCHIMEDES";"FR;EE;HU;EL;MK;UK;CZ;RS;BG;IE;IL;SK;NO;CH;IT;HR";/ITT;1;0;0;1;0;0 103581;298927;PFMS;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IEF;FP7;Pattern Formation in Microorganism Suspensions: Shear and Confinement;2012-09-04;2014-09-03;;"'Microorganisms are present in almost every part of temperate aqueous environments, and they are heavily involved in pathoenic infection, digestion, reproduction and carbon dioxide capture and mixing in the oceans. Therefore, understanding their motility, collective dynamics and interaction with the environment is a key issue to overcome important challenges of our time such as collapse of ecological systems, global warming, and environmental pollution. The objective of this proposal is to contribute to our understanding of the behavior of swimming microorganisms, focusing particularly on their collective dynamics caused by interaction with surrounding hydrodynamic conditions, flow shear and confinement. Two state-of-the-art collective behaviors of microorganisms are considered: bioconvection and particle-stress-driven instability, and interaction of the collective dyanamics with shear flows and confinement will be analyzed using the-state-of-the-art linear and nonlinear stability theories, which are the candidate's particular expertise. A part of the theoretical prediction, particularly for particle-stress-driven instability, will also be verified by conducting a laboratory experiment. The work program in this proposal is designed to complete post doctoral training of the candidate, who has been trained within the European network. Interdisciplinary nature of the project will greatly improve the candidate's future mobility cutting across fluid mechanics, biophysics and applied mathematics. The results of this project is expected to provide a solid basis for understanding and predicting the collective dynamics of swimming microorganisms, and it will significantly contribute to the European excellence of environmental and energy science.'";209033,4;209033,4;FP7-PEOPLE-2011-IEF;/MC-IEF;THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;UK;;;/SCI;1;0;0;1;0;0 96990;263954;TIME;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-ITN;FP7;Translation Research Training: An integrated and intersectoral model for Europe;2011-01-01;2014-12-31;;"Faced with important social, professional and technological developments, research training in translation and multilingual/multimedia communication must meet new needs and develop common strategies between private/public institutions and academia. TIME will create a unique training platform to meet these needs. General objectives 1. To train four ESRs and one ER to become experts in translation and multilingual/multimedia communication, making them conscious of Europe’s needs for linguistic diversity and fit to meet the new market requirements of the European knowledge-based society; 2. To create a network that is able to produce a new generation of doctoral graduates that meet the profile mentioned above; 3. To increase the involvement of private/public institutions in research training in Translation Studies by kick-starting joint research training, which will lead to sustainable cooperation; 4. To raise the awareness of industry of the scope and relevance of translation research and, conversely, to raise awareness within academia of the needs of private and public institutions; 5. To establish the foundations for an academic/private sector joint PhD training and a joint doctoral degree. Specific objectives 1. To provide insight into the state and evolution of the European translation market, i.e. knowledge about the future demand and supply for translation services other than from a purely economic viewpoint; 2. To provide insight into the benefits for private/public institutions of a long-term strategic approach to translation and multilingual/multimedia communication, which will facilitate all forms of exchange and integration and promote linguistic diversity in Europe; 3. To formulate best practices for this long-term strategic approach. Interdisciplinary objectives 1. To use the insights generated by private/public sector-driven research for PhD training and vice versa; 2. To become partner in the industry of language technology.";1228978;1228978;FP7-PEOPLE-2010-ITN;/MC-ITN;KATHOLIEKE UNIVERSITEIT LEUVEN;BE;"UNIVERSITAT ROVIRA I VIRGILI;TURUN YLIOPISTO;ASTON UNIVERSITY";"ES;FI;UK";"/EDU;/NET";1;0;0;1;0;0 99896;293402;IF INTERACTIONS;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-CIG;FP7;Self-Assembly, Structures and Interactions of Cell Specific Cytoskeleton;2011-08-01;2015-07-31;;"Cell specificity plays a critical role in the complexity high-order organism can achieve. The cascade of signals and events leading embryonic stem-cells to differentiate has been a major research topic in the last century. During differentiation, cell-specific proteins are expressed in order to accommodate the necessary specific functions. Among other cell/tissue specific modulations, the cytoskeleton is altered during differentiation and at different developmental stages of a specific cell type. This is presumably to account for the constantly-changing mechanical strains and stresses, as well as interactions with the environment, intracellular transport and cell motility. We propose to study a class of cytoskeleton proteins, named intermediate filaments, which are expressed at various developmental stages and cell/tissue types of neuro-muscular origin. Interdisciplinary studies will include protein purification, biochemical characterization, high-resolution microscopy, as well as structural studies in hydrated state using small-angle x-ray scattering. Combining these multiple techniques, we aim to model and reveal how minor molecular differences between proteins from the intermediate filament family are translated into supramolecular forces that, in turn, alter the cytoskeleton elastic and mechanical properties.";100000;100000;FP7-PEOPLE-2011-CIG;/MC-CIG;TEL AVIV UNIVERSITY;IL;;;/SCI;1;0;0;1;0;0 103985;304255;SRCD-IP;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-CIG;FP7;Self-regulation and cognitive development of infants facing poverty;2012-07-01;2016-06-30;;Children raised in families experiencing poverty face significant adversity early in life that puts them at much greater risk of developing learning difficulties. There is a pressing need to develop early screening and intervention strategies that will be cost-effective and easy to deliver in the community. This proposal brings together research in two fields: cognitive neuroscience and the study of infant-parent interaction, aiming to investigate how the socio-economic status of a family and poor cognitive outcomes later in life are mediated by infant’s emerging self-regulation strategies during interactions with parents in the first 12 months of life and follows up their language and communication outcomes at age 18 months. A better understanding of both social and cognitive basis of developmental difficulties those children face will lead to new early screening and possibly intervention strategies. Interdisciplinary, cutting edge eye-tracking and microanalysis of infant-parent interaction methods will be used to study the subject and to delineate the predictors of emerging problems in infant speech, language and communication development. Application work leading to the development of new screening tools and eye-tracking technology will be undertaken in partnership with academics and industry partners.;100000;100000;FP7-PEOPLE-2011-CIG;/MC-CIG;UNIWERSYTET WARSZAWSKI;PL;;;/SCI;1;0;0;1;0;0 108641;334470;REPROAB;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-CIG;FP7;Controlling Reproduction in Post-communist Romania: The Abortion Issue;2013-10-01;2017-09-30;;"'The abortion ban (1966-1989) during Ceausescu’s regime is considered one of the most repressive reproduction policies of the twentieth century. Immediately after the fall of the communist regime, the new Romanian government legalized abortion on request. Studies have documented the demographic consequences of the communist pronatalism in the early 1990s, but very little research has focused specifically on controlling reproduction in postcommunist Romania between the State and the individual. Based on long-term ethnography of the abortion issue in post-communist Romania, this research project seeks to understand the legacy of the former abortion ban in terms of institutional norms and individual practices. Interdisciplinary in nature, and primarily qualitative, it combines a social anthropology and Memory Studies approach in order to (1) inventory the public policies concerning abortion after 1989, as well as associated debates, and (2) analyze the individual practices of the medical profession, and their evaluation by the patients, both in a synchronic (participatory observation in abortion- providing facilities) and diachronic perspective (in-depth interviews, following a social memory approach). The associated fieldwork will be situated in south-central contemporary Romania (Bucharest and Prahova jurisdiction) and will involve several case studies in urban and rural settings. The overall scientific goal of the project is to provide, from a social anthropology point of view, a comprehensive understanding of the relations between past and present when dealing with biopolitics in a post-totalitarian regime. In this sense, postcommunist Romanian realities will be taken as a case-study, but insights will be made in the nature, the scope and the practice of biopower at the European level after 1989, between national agendas and international norms.'";100000;100000;FP7-PEOPLE-2012-CIG;/MC-CIG;UNIVERSITATEA DIN BUCURESTI;RO;;;/LIF;1;0;0;1;0;0 109672;610307;MONTENIGHT2013;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-NIGHT;FP7;MONTENIGT2012;2013-05-01;2013-11-30;;The project Researchers’ Night in Montenegro 2013 will be a successful continuance of its precedents Researchers’ Nights 2009-2012, organized by the same consortium, Montenegrin Science Promotion Foundation – PRONA, Natural History Museum and Ministry of Science, and strengthen efforts put in bridging the gap between the researchers and wider public. All events will take place on Friday, 27 September, from 12:00 – 24:00, with the central events (Hands-on-experiments, Science and Art installations, Gala opening, Movie projections, Interdisciplinary and inter-generational workshops, ‘Open science Show and Quiz’, Astronomical workshop, Science kindergarten, Concert) happening at the main Square in Podgorica and a series of smaller scale activities in Podgorica (University of Montenegro, Natural History Museum of Montenegro and “Delta” and “Gintas” Shopping Malls) and five other towns in Montenegro (Kotor, Tivat, Danilovgrad, NIksic and Bijelo Polje). Target groups of the projects are: high school students, university students, young people in general, preschool children, elementary school pupils, parents, school authorities and teachers, media and general public. The implementation plan implies having at least 10000 of direct participants, and to cover at 44% of Montenegrin population or 290000 people with awareness campaign. At least 250 people, from which 50 researchers coming from different sectors and fields of research, will implement the Researchers’ Night’s activities. Researchers’ Night will have a higher regional and international character. The main aim of 2013 project is to upgrade the role of researchers within the society. Project Researchers’ Night is fun, educational and unique event that gathers general population and researchers from academic institutions, the business sector, schools, young-talent programs, various NGOs, governmental institutions, international agencies, and guests - researchers from around the region and world, including diaspora.;38199,5;35000;FP7-PEOPLE-2013-NIGHT;/CSA-SA;"""Fondacija za promovisanje nauke """"PRONA""""""";ME;"J.U. PRIRODNJACKI MUZEJ CRNE GORE PODGORICA;MINISTARSTVO NAUKE";ME;/LIF;1;0;0;1;0;0 106420;301816;ETHICAL RISK;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IEF;FP7;An ethical framework for the risk-based regulation of biomedical research;2013-09-15;2015-09-14;;"Background: Biomedical research has important social and economic value. It helps to promote individual and population health, boosts competitiveness and innovative capacity, and thereby contributes to economic growth. Yet, biomedical research exposes study participants to risks. Research also poses risks to public health when the science is poor. The ethical acceptability of research therefore critically depends on protecting participants’ rights and safety, while promoting the scientific and social value of the research. Research regulations are designed to ensure that these requirements are met. -- Patient organizations, investigators, sponsors, and others are increasingly dissatisfied with the existing regulatory framework. Many call for a “risk-based” system of research oversight that matches various safeguards – including independent ethical review and safety monitoring and reporting – to the level of risk posed by the research (e.g., revision of the EU Clinical Trials Directive). However, it remains unclear what such a system should look like. Objectives: 1) To address the ethical questions raised by risk-based research regulations, including the stratification of research risks and the relation between risk, consent, and the scientific and social value of the research. 2) To develop an ethical framework for risk-based research regulations. Methods: Interdisciplinary study that combines conceptual and normative analysis, policy analysis, and expert consultation. Target audience: Policymakers, research regulators, research ethicists, and others interested in the ethics and regulation of risk. Impact: By calibrating safeguards and protections to the level of risk posed by a study, the envisioned framework will help to promote valuable research consistent with adequate subject protection. This is a prerequisite for responsible progress in health. The project will inform current policy and ethical debates both on a national and international level.";209033,4;209033,4;FP7-PEOPLE-2011-IEF;/MC-IEF;KING'S COLLEGE LONDON;UK;;;/SCI;1;0;0;1;0;0 106806;297921;TOMOMECH;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IEF;FP7;Nanomechanics of natural materials from combining tomography and finite element modelling;2013-07-01;2015-06-30;;'Porous sedimentary rocks compose a large part of the European coastline and are major oil reservoirs in Europe, yet little is not known about their nanoscale structure and mechanical properties even though these parameters are linked to macroscale behaviour. The aim of TOMOMECH is to combine X-ray tomography and finite elements modelling (FE) on the nanoscale to make predictions about the stability of e.g. chalk cliffs and the remaining oil in depleting reservoirs. My model for determining stability will be versatile, which I will demonstrate by applying it to biomineralised shells as well, to elucidate nature's design strategies. The combination of tomography and FE has been employed successfully before to examine the structure and functionality in trabecular human bone on the microscale. A main objective of TOMOMECH is to transfer this approach to the nanoscale and adapt it for determining pore structure in sedimentary rocks. The results will be applicable to coastal protection, oil production and biomimetic materials. Through a direct connection to industrial partners, a focus on applicability is ensured. My background in Physics, combining X-ray techniques and modelling from the molecular to the continuum scale will underpin this project but I will also benefit from the training in new nanoscale characterisation techniques that I will receive. Interdisciplinary research has been a major topic in my career and TOMOMECH will give me the opportunity to further broaden my scientific background. The approach I will develop and the chance to run my own project will give a good push in my future career. Mentoring by my host, Prof. Stipp, who is an expert in nanoscale characterisation, and interaction with the Nano-Science Center, Copenhagen, will ensure progress, help increase my network and provide tremendous benefit.';228082,2;228082,2;FP7-PEOPLE-2011-IEF;/MC-IEF;KOBENHAVNS UNIVERSITET;DK;;;/SCI;1;0;0;1;0;0 86770;201917;PREDICT;ONG;FP7-HEALTH;HEALTH-2007-2.2.2-4;FP7;Increasing the PaRticipation of the ElDerly in Clinical Trials;2008-02-01;2010-07-31;http://www.predicteu.org/;AIM. To investigate the reasons for the exclusion of the elderly in clinical trials and to provide solutions for this problem. INTRODUCTION. Although the elderly account for high drug consumption, they are underrepresented in clinical trials. With an increasingly ageing European population it is essential to demonstrate the efficacy and safety of drugs. Clinical trials need to take into account the relevant issues of this population, i.e. changed metabolism, multiple chronic conditions and poly-pharmacy. To examine this issue and effect a paradigm shift it is necessary to target gatekeepers and stakeholders of clinical trials. METHODS. The project will be coordinated by the Medical Economics and Research Centre, Sheffield, with guidance from the Centre for Interdisciplinary Research on Ageing at Keele University, UK. The 5 work packages (WP) will be carried out by a multi-disciplinary team of highly qualified experts in Geriatrics, Gerontology and social sciences. WP1 will involve a systematic review of the literature and review of ongoing clinical trials to assess the extent of exclusion of the elderly. Based on these findings WP2 and WP 3 will investigate why the elderly are underrepresented in clinical trials and what can be done to improve their participation. This will be carried out in 9 countries: UK, Spain, Holland, Italy, Poland, Lithuania, Romania, Israel and the Czech Republic. WP2 will research the views of health professionals and ethicists using structured questionnaires. WP3 will explore the perceptions of older patients and carers using a focus group methodology. For WP4, the recommendations from WP2 and WP3 will be used to develop a charter for the elderly in clinical trials. WP5 will disseminate and implement the findings. CONCLUSION. PREDICT will promote the inclusion of the elderly in clinical trials in Europe. This project will facilitate the improvement of the rights of older people and the quality of health care for the ageing population.;840612,62;750047;FP7-HEALTH-2007-A;/CSA-SA;MEDICAL ECONOMICS AND RESEARCH CENTRE, SHEFFIELD;UK;"UNIVERSITY OF KEELE;ANA ASLAN INSTITUTE OF GERONTOLOGY AND GERIATRICS;BEN-GURION UNIVERSITY OF THE NEGEV;KAUNO MEDICINOS UNIVERSITETAS;CORPORACIO SANITARIA PARC TAULI DE SABADELL;VERENIGING VOOR CHRISTELIJK HOGER ONDERWIJS WETENSCHAPPELIJK ONDERZOEK EN PATIENTENZORG;UNIWERSYTET JAGIELLONSKI;UNIVERZITA KARLOVA;UNIVERSITA DEGLI STUDI DI PERUGIA;MEDICAL RESEARCH COUNCIL";"UK;RO;IL;LT;ES;NL;PL;CZ;IT";"/LIF;/SOC;/MED";1;0;0;1;0;0 103882;301731;JOBS TO RENT;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IEF;FP7;"""Migration and Temporary Agency Work in the EU welfare, tourist and agricultural sectors""";2012-10-01;2014-09-30;;"'Migrants constitute the most significant pool of workers at the disposal of the EU member states that wish to expand flexible forms of labour in order to meet the demands of their increasingly ageing and diverse population. They usually fit best the profile of the poor and vulnerable segments of society that would readily take the low status, low pay jobs, yet their freedom of movement towards (and within) the EU labour markets is restricted by inflexible migration policy regimes leaving the space open to a wide array of social networks to construct pathways of entry. Interdisciplinary research touching on the issue of the migrants’ integration in host societies has indicated so far that the ways migrants enter the host country are somehow related with the work opportunities and conditions they experience. This project aims to systematically investigate the factors determining the forms of temporary agency work in specific economic sectors. The key contribution of the proposed study from a conceptual perspective is that it tackles issues having to do with the socioeconomic context of work and its organisation as well as questions related to the socio-political framing of the (migrant) worker’s mobility. From an empirical and policy-related perspective, the significance of this research project consists in addressing the question of temporary agency work in a comparative setting across labour markets with different settings of work and across two EU countries experiencing different and managing differently migration flows.'";209033,4;209033,4;FP7-PEOPLE-2011-IEF;/MC-IEF;UNIVERSITY OF BATH;UK;;;/SCI;1;0;0;1;0;0 106640;324292;BIOFUR;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IAPP;FP7;BIOpolymers and BIOfuels from FURan based building blocks;2013-01-01;2016-12-31;;"'The BIOFUR project consists of three partners. The SME Avantium Chemicals (AVT - NL), selected as one of the Cleantech top 100 companies in 2011 and the Centre National de la Recherche Scientifique (CNRS - FR) and the University of Messina (UNIME - IT), both leaders in their respective fields. This multi-sectorial research work will contribute to breakthrough knowledge on the catalytic furanic conversion fundamentals and will be necessary for a sustainable technological development of these novel polyester materials and fuels based on renewable resources. The project consist of three workpackages: WP1: Production, Characterization, Optimisation and Environmental Impact of the Production of Polyesters; WP2: Development of Nanostructured Catalysts to improve the Performances and Sustainability of the Catalytic Conversion and Upgrading of Furanics, and; WP3: Managerial, Interdisciplinarity, Intersectoral and Dissemination aspects. The BIOFUR project shows that the proposed knowledge transfer for the three host organizations through the secondment of their own staff and the recruitment of researchers from outside the partnership is very beneficial for the host organizations by significantly increasing their research quality and overall RTD capabilities and competitiveness. The proposed dissemination and outreach activities will make sure that also to the greater European community will benefit from this project. The Coordinator of the BIOFUR project is Dr. Ed de Jong of AVT and the other lead researchers are Prof. Gabriele Centi of UNIME and Prof. Nicolas Sbirrazzuoli of CNRS.'";920563,04;920563,04;FP7-PEOPLE-2012-IAPP;/MC-IAPP;AVANTIUM CHEMICALS BV;NL;"UNIVERSITA DEGLI STUDI DI MESSINA;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS";"IT;FR";/LIF;1;0;0;1;0;0 111102;335890;STATORG;ONG;FP7-IDEAS-ERC;ERC-SG-SH2;FP7;State Encroachment on Civil Society? A Comparative Study of Parties, Interest Groups and Welfare-Providing Organizations in Contemporary Democracies;2013-12-01;2019-11-30;;This interdisciplinary project compares the regulatory frameworks governing membership-based, voluntary organizations (VOs) in long-lived democracies and assesses how these frameworks affect VOs’ operations. It studies interest groups, parties and welfare-providers as three VO types interacting with the state at different stages of the political process. State control over organized civil society is at odds with pluralist values and supposed to weaken VOs’ linkages to citizens. Simultaneously, specialist literatures in political science and sociology point to ‘their’ VOs’ entanglement with the state, while comparative legal and public policy scholars note that governments, in recent reforms, increased their control over which VOs receive funds and how funds can be used. In times of austerity, welfare state retrenchment and declining trust in elected institutions the regulatory frameworks governing VOs are changing, deeply affecting organizational life in a democracy. Only an up-to-date overview of current frameworks allows us to examine whether close state-voluntary relations compromise VO autonomy and reduce VOs’ beneficial effects for democracy. This project tackles these important issues through two modules integrated through a mixed methods design. Module 1 develops an analytical framework to compare the regulation of VOs cross-nationally and applies it to 19 long-lived democracies. Based on this mapping, it specifies and theorizes distinct normative conceptions of state-voluntary relations underpinning democracies. Offering a new approach to VO development, Module 2 studies qualitatively (through in-depth interviews and document analysis) how individual VOs adapt to ‘most different’ regimes - each regime representative of one state-voluntary conception identified in Module 1-, while testing quantitatively (through event history analysis) how far the features that VOs acquire in this process affect their likelihood to survive under varying regulatory conditions.;864972;864972;ERC-2013-StG;/ERC-SG;THE UNIVERSITY OF EXETER;UK;;;/SOC;1;0;0;1;0;0 188564;606988;SIMDALEE2;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-ITN;FP7;"""Sources, Interaction with Matter, Detection and Analysis of Low Energy Electrons 2""";2014-09-01;2018-08-31;;"'The purpose of the SIMDALEE2 (Sources, Interaction with Matter, Detection and Analysis of Low Energy Electrons) network is to establish a world-class research training platform for the science and technology of nanoscale manipulation and analysis using low energy electrons. Apart from an effective and well-structured training programme, the network will pursue the following scientific goals: (1) optimizing beam size by correlating contemporary field emission (FE) theory with high resolution holographic measurements of magnetic and electric fields of FE tips with different shapes, both with and without primary electron optics; (2) putting the understanding of the contrast mechanism of electron beam techniques on a sound footing by comparing physical models with novel benchmark spectra acquired using a coincidence technique; (3) improving detection as well as understanding of emitted energy-, angular-, and spin-dependent spectra. This issue will be addressed for the common case of detectors in the a field-free environment, and for the special case when the emitted electrons encounter an electric field prior to detection; (4) Electron beam modification of nanostructured surfaces; (5) Progress in the aforementioned fields will lead to the development of an innovative prototypical methodology for nanoscale characterization with electron beams in the form of a compact desktop-type Near-Field-Emission Scanning Electron Microscope (NFESEM). Finally, (6) the economic impact and feasibility of low energy electron beam methodology will be investigated within the project. Accordingly, the ESRs and ERs will develop and acquire experience on a comprehensive methodology beneficial for any industrial or academic laboratory employing or developing electron beam techniques for natural science studies, as well as for biology and engineering. Their participation in this interdisciplinary and intersectoral network will greatly further their career opprtunities in S&T in Europe.'";3399600,45;3399600,45;FP7-PEOPLE-2013-ITN;/MC-ITN;TECHNISCHE UNIVERSITAET WIEN;AT;"THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;FORSCHUNGSZENTRUM JULICH GMBH;INSTITUT JOZEF STEFAN;NATIONAL TECHNICAL UNIVERSITY OF ATHENS - NTUA;UNIVERSITA DEGLI STUDI ROMA TRE;USTAV PRISTROJOVE TECHNIKY AVCR VVI;UNIVERSITY OF YORK;EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH;FEI ELECTRON OPTICS BV;A.P.E. RESEARCH SRL;ROENTDEK - HANDELS GMBH";"UK;DE;SI;EL;IT;CZ;CH;NL";/LIF;1;0;0;1;0;0 105262;312603;PROCON;ONG;FP7-IDEAS-ERC;ERC-SG-SH6;FP7;PROduction and CONsumption: Textile Economy and Urbanisation in Mediterranean Europe 1000-500 BCE;2013-04-01;2018-09-30;;A textile is not simply a system of spun, twisted, or spliced fibres, but first and foremost a result of complex interactions between resources, technology, and society. Textile production and consumption is both ubiquitous and multi-faceted since, after food and shelter, textiles constitute the next most important necessity for people in all societies. Far from being a minor material, the production and consumption of textiles is at the heart of fundamental shifts in economy, trade and social relationships. In the ancient past, textile production was an economic necessity which has confronted all societies and carried particular importance in the growth of urbanism and state formation. The aim of the project PROCON is to investigate the role of textiles in the urbanisation and state formation of Mediterranean Europe (Greece, Italy, Spain) from 1000 to 500 BC and to demonstrate that textile production and consumption were a significant driving force of the economy and in the creation and perception of wealth. The focus is on the importance of the production and consumption of textiles for the development of city-states (as clothing, elite regalia, trade and exchange items, utilitarian textiles such as sails) and the implications of this for other aspects of the economy, such as the use of farm land, labour resources and the development of urban lifestyles. This interdisciplinary project is unique in that it takes developments in a relatively specialist research field (textile archaeology) and applies them towards modelling the dynamics behind a broader question of urbanisation in Mediterranean Europe. Using established and novel approaches, the project results will transform the landscape of Early Iron Age European research by providing new data sets, demonstrating textile production and consumption as major economic and social factors behind urbanism. In historical context, the PROCON project continues the European excellence in the field of textile research.;1499877;1499877;ERC-2012-StG_20111124;/ERC-SG;THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;UK;UNIVERSITY COLLEGE LONDON;UK;"/SCI;/SOC";1;0;0;1;0;0 101650;286264;ANISTEM;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IAPP;FP7;"""Induced pluripotent stem cells in rabbit, pig""";2011-11-01;2015-10-31;;"'The ANISTEM project is aimed at creating a 4-years training and transfer of knowledge program between a Hungarian SME and a Dutch and a Hungarian University in the field of stem cell research in mammalians (rabbit, pig), which will open opportunities for a mutually beneficial long term partnership of veterinary and medical research and for applications between the industrial and academic participants. The scientific and industrial aim of ANISTEM is to generate new comparative information on the generation, maintenance and characteristics of induced Pluripotent Stem (iPS) cells in rabbit and pig and on their differentiation towards the cardiac lineage. The physiology of cardiomyocytes from iPS cells from rabbit and pig will be compared and their ability to report drug responses faithfully will be investigated. The ANISTEM project links intersectorial research activities in SME and Academia in different mammalian and cellular systems. An interdisciplinary approach is needed using methods from cell biology, structural cell biology, developmental biology, molecular biology and finally bioinformatics. Training and transfer of knowledge activities are structured to ensure maximum efficiency in developing and exchanging new standards between industry and academia and to expose the participating researchers to different environments and schools of thoughts. The main impact of the project is expected to be in integrating efforts in stem cell biology, biomedical models and cell therapy between industry and academia for long term collaboration. Better stem cell differentiation protocols in mammalians will potentially allow for validation and development of iPS cells as highly desirable alternatives for live animals for drug testing, disease modeling and research on regenerative medicine.'";1561753;1561753;FP7-PEOPLE-2011-IAPP;/MC-IAPP;SZENT ISTVAN UNIVERSITY;HU;"BIOTALENTUM TUDASFEJLESZTO KFT;UNIVERSITEIT UTRECHT";"HU;NL";/IND;1;0;0;1;0;0 110750;340538;UNIQDS;ONG;FP7-IDEAS-ERC;ERC-AG-PE7;FP7;"Universal Framework for Charge Transport in Quantum Dot Systems";2013-11-01;2018-10-31;;The field of quantum dots (QDs) is one of the major growth areas in interdisciplinary field of physics, materials, chemistry, and engineering for the exploration of fundamental physical properties and potential/new functionalities. This will serve as a basis for creation of unique applications such as new display/lighting, photovoltaic device, TFTs and image sensors. However, there are serious impediments to the device performance such as high efficiency and longer life time due to the lack of understanding in charge transport and light-matter interaction mechanism in QD networks. Therefore, the proposed work is a comprehensive and fundamental understanding of underlying physics for charge transport in i) a single QD and surface, ii) QD/QD, iii) QD/interface/matrix, iv) QD/layer and /electrode, and v) bulk QD network systems and the creation of any real devices with new functionality. Enormous opportunities will arise from many unanswered questions of general nature/fundamental physical aspects of QDs related to charge transport that have still to be addressed. Thus, we will highlight and focus on strongly linked key themes and challenges that are at the heart of our proposed work. The main emphasis of proposed work will be on the understanding and control of charge transport dynamics in various QD systems, even though we explore the development of meaningful technologies and new devices based on QDs in the proposal. Our most intriguing issue is to expand the basic understanding of QDs for their potential applications. We will study interface dipole design/control, computational engineering for charge transport, analysis of the above five subsets, and will realise them into a full system with QD networks. Another challenge lies in integrating new QD materials with flexible/large-area substrates by monolayer-level control. We also propose the development of new synthetic routes for QDs with stable surface for supporting the above charge transport. This work will be underpinning research aimed at the development of the charge transport based QD devices with high efficiency and longer lifetime. These provide enormous opportunities to enable us not only to broaden and deepen our knowledge/experience in this area, but also to make rational predictions and open new device/system concepts unique to QD networks.;2454650;2454650;ERC-2013-ADG;/ERC-AG;THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;UK;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;UK;"/PSE;/ICT;/TEL;/NET";1;0;0;1;0;0 110402;335814;JAGEUROPE;ONG;FP7-IDEAS-ERC;ERC-SG-SH6;FP7;"""The Jagiellonians: Dynasty, Identity and Memory in Central Europe""";2013-10-01;2018-09-30;;"'This ERC Starter Grant project will fund an interdisciplinary, transnational and groundbreaking study of the Jagiellonian dynasty (c.1386-1596) and its role, and legacy, in the development of identity in what we now call Central Europe. One of the most spectacularly successful of early modern dynasties, comparable only to the Habsburgs, in 1500 the Jagiellonians ruled a third of continental Europe, an area comprising no fewer than 14 present-day states. Uniquely among European dynasties in this period, the Jagiellonians created a dynastic regional hegemony, a geographical ‘bloc’ of neighbouring monarchies. Our knowledge of the Jagiellonians is, however, limited and highly fragmented along both national and disciplinary lines. The project will provide the first treatment of this leading Renaissance-era dynasty as a supra-national entity; it will offer a major new investigation of Renaissance dynasty itself as a political and cultural institution; explore the part played by the Jagiellonians in the evolution of pre-modern local or 'national' and regional identities, and investigate the ways in which divergent memories of their rule have, from 1596 onwards, shaped modern national identities in Central Europe. The project will transcend scholarly divisions – between disciplines (e.g. art history, anthropology, political history), between period specialisations (late medieval, early modern, modern) and between individual national historiographies (Polish, German, Czech etc.), to offer a metahistory of the meanings attributed to this landmark European dynasty, from the founder Jogaila (d.1434) to Radek Sikorski, Poland’s current foreign minister. The research will be undertaken by a multi-lingual team of 5 post-doctoral researchers, led by the PI, drawing on a range of written and visual sources produced by and about the Jagiellonians over six centuries.'";1407037;1407037;ERC-2013-StG;/ERC-SG;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;UK;;;"/SCI;/SOC";1;0;0;1;0;0 111449;313082;RISIS;ONG;FP7-INFRASTRUCTURES;INFRA-2012-1.1.2.;FP7;Research infrastructure for research and innovation policy studies;2014-01-01;2018-06-30;;"The RISIS project aims at creating a distributed research infrastructure to support and advance science and innovation studies. This will give the field a strong scientific push forward, and at the same time, provide a radically improved evidence base for research and innovation policies, for research evaluation, and for the quality of policy relevant indicators. The field of science and innovation studies is interdisciplinary, and is related to political sciences, sociology, management and economics. It has a strong quantitative core - with specialties such as scientometrics, technometrics and more widely indicators design - but for many important questions data were lacking or small scale only. This has made the field too much dependent on a few pre-existing datasets. However, during the last decade important efforts have been undertaken to develop new datasets on burning issues such as industrial R&D globalisation, patenting activities of firms, university performance, Europeanisation through joint programming, or the dynamics of nano S&T. Another new characteristic of the field is the development– together with computer scientists – of software platforms for collecting, integrating and analysing ever more data. Data and platforms are currently owned and/or located at many different organizations, such as individual research groups, companies, and public organizations – with very restricted access to others. Through deploying various networking and access strategies, and through joint research, RISIS will decisively open, harmonize, integrate, improve, and extend their availability, quality and use.";7157673,2;4999184;FP7-INFRASTRUCTURES-2012-1-RTD;/CP-CSA-Infra;UNIVERSITE DE MARNE LA VALLEE;FR;"JOANNEUM RESEARCH FORSCHUNGSGESELLSCHAFT MBH;NORDISK INSTITUTT FOR STUDIER AV INNOVASJON, FORSKNING OG UTDANNING;Institut für Forschungsinformation und Qualitätssicherung;AIT AUSTRIAN INSTITUTE OF TECHNOLOGY GMBH;UNIVERSITEIT LEIDEN;THE SAMUEL NEAMAN INSTITUTE FOR ADVANCED STUDIES IN SCIENCE AND TECHNOLOGY OF THE TECHNION LTD (PSC);THE UNIVERSITY OF MANCHESTER;STICHTING VU;DEUTSCHES ZENTRUM FUR HOCHSCHUL- UND WISSENSCHAFTSFORSCHUNG GMBH;AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS;THE UNIVERSITY OF SUSSEX;UNIVERSITA DELLA SVIZZERA ITALIANA;CONSIGLIO NAZIONALE DELLE RICERCHE;POLITECNICO DI MILANO;UNIVERSITA DEGLI STUDI DI ROMA LA SAPIENZA";"AT;NO;DE;NL;IL;UK;ES;CH;IT";/SCI;1;0;0;1;0;0 109822;337183;AEROBIC;ONG;FP7-IDEAS-ERC;ERC-SG-PE10;FP7;Assessing the Effects of Rising O2 on Biogeochemical Cycles: Integrated Laboratory Experiments and Numerical Simulations;2013-09-01;2018-08-31;;"The rise of atmospheric O2 ~2,500 million years ago is one of the most profound transitions in Earth's history. Yet, despite its central role in shaping Earth's surface environment, the cause for the rise of O2 remains poorly understood. Tight coupling between the O2 cycle and the biogeochemical cycles of redox-active elements, such as C, Fe and S, implies radical changes in these cycles before, during and after the rise of O2. These changes, too, are incompletely understood, but have left valuable information encoded in the geological record. This information has been qualitatively interpreted, leaving many aspects of the rise of O2, including its causes and constraints on ocean chemistry before and after it, topics of ongoing research and debate. Here, I outline a research program to address this fundamental question in geochemical Earth systems evolution. The inherently interdisciplinary program uniquely integrates laboratory experiments, numerical models, geological observations, and geochemical analyses. Laboratory experiments and geological observations will constrain unknown parameters of the early biogeochemical cycles, and, in combination with field studies, will validate and refine the use of paleoenvironmental proxies. The insight gained will be used to develop detailed models of the coupled biogeochemical cycles, which will themselves be used to quantitatively understand the events surrounding the rise of O2, and to illuminate the dynamics of elemental cycles in the early oceans. This program is expected to yield novel, quantitative insight into these important events in Earth history and to have a major impact on our understanding of early ocean chemistry and the rise of O2. An ERC Starting Grant will enable me to use the excellent experimental and computational facilities at my disposal, to access the outstanding human resource at the Weizmann Institute of Science, and to address one of the major open questions in modern geochemistry.";1472690;1472690;ERC-2013-StG;/ERC-SG;WEIZMANN INSTITUTE OF SCIENCE LTD;IL;;;"/PSE;/ENV;/EAR";1;0;0;1;0;0 100538;295552;CEREBRAD;ONG;FP7-EURATOM-FISSION;Fission-2011-3.1.1;FP7;Cognitive and Cerebrovascular Effects Induced by Low Dose Ionising Radiation;2011-10-01;2015-03-31;http://www.cerebrad-fp7.eu/;"The major elements of scientific uncertainty in the context of radiation protection policy and of risk assessment for cerebrovascular diseases, set the following key topics (1) the direct assessment of health effects through epidemiological studies of groups exposed to low doses, (2) doses-response and biological effects from different types of radiation and (3) the biological processes in cells and tissues mediating the cerebrovascular effects of low-dose radiation. These 3 topics have been identified as priorities by the HLEG, the MELODI Strategic Agenda and ARCH (Agenda for Research on Chernobyl Health), and will be covered in the CEREBRAD (Cognitive and Cerebrovascular Effects Induced by Low Dose Ionising Radiation) project. CEREBRAD will address the problem of cerebrovascular effects in humans: in individuals that were exposed in utero, in cohorts of adults from the Chernobyl liquidators, and in children receiving low doses to the brain during cancer radiotherapy. We will study cognitive effects in animal models exposed to radiation at different stages of brain development, with special emphasis on early postnatal exposures, and will examine the initial and late effects induced in brain by irradiation at the cellular and molecular levels. The main concern of CEREBRAD is to identify the potential risk of doses below 100 mGy delivered to a young child. To inform on risk estimates of the effect from internal and external exposures, as well as synergistic effect with other environmental pollutants, all these different conditions will be evaluated. The consortium is an interdisciplinary team of radiobiologists, epidemiologists, experts in neurodegenerative diseases, genomics, proteomics and bioinformatics, paediatricians and dosimetrists. Special attention will be paid to efficient project management, training, dissemination and communication with stakeholders and the general public.";4905635,4;2999516,8;FP7-Fission-2011;/CP-FP;STUDIECENTRUM VOOR KERNENERGIE / CENTRE D'ETUDE DE L'ENERGIE NUCLEAIRE;BE;"UNIVERSITAT ROVIRA I VIRGILI;INSTITUT GUSTAVE ROUSSY;HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH;ARISTOTELIO PANEPISTIMIO THESSALONIKIS - EIDIKOS LOGARIASMOS KONDILION EREVNAS;STATE INSTITUTION RESEARCH CENTER FOR RADIATION MEDICINE OF THE ACADEMY OF MEDICAL SCIENCES OF UKRAINE;NEMZETI NEPEGESZSEGUGYI KOZPONT;THE UNIVERSITY OF BIRMINGHAM;UPPSALA UNIVERSITET;AGENZIA NAZIONALE PER LE NUOVE TECNOLOGIE, L'ENERGIA E LO SVILUPPO ECONOMICO SOSTENIBILE;ORSZAGOS FREDERIC JOLIOT-CURIE SUGARBIOLOGIAI ES SUGAREGESZSEGUGYI KUTATO INTEZET;ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM";"ES;FR;DE;EL;UA;HU;UK;SE;IT;NL";/FIS;1;0;0;1;0;0 197825;609019;SINFONIA;ONG;FP7-ENERGY;ENERGY.2013.8.8.1;FP7;Smart INitiative of cities Fully cOmmitted to iNvest In Advanced large-scaled energy solutions;2014-06-01;2019-05-31;;"'SINFONIA utilizes EU funds to bolster public/private resources and provide European added value to already committed district refurbishment master plans of two middle sized European cities (Bolzano, Italy and Innsbruck, Austria), the targeted performances of which combine three key features thanks to industry involvement: i) unique cooperation between the cities belonging to the same climate zone in Europe, but working under different regulatory regimes (Austria, Italy), ii) single collective ambition in reducing energy needs to meet human activity requirements, and the related CO2 emissions (40 to 50 % primary energy savings per district, 20 % increase of the share of renewable energy uses), iii) several innovations in network infrastructures and technology interfaces that enable smarter use of energy at district level, a stepping stone to guarantee a reliable and progressive transition toward low carbon cities. Moreover, SINFONIA aims at validating a comprehensive, interdisciplinary, refurbished city district model where the potential for scalability and replication by middle-sized European cities is built and validated during demonstration, based on energy technologies deployed by the two pioneer cities. This model emphasizes the role of an innovative integrated energy system approach, linking energy efficiency and CO2 abatement. The model robustness is reinforced by five “early adopter” cities which are full project partners in Cyprus (Pafos), France (La Rochelle), Germany (Rosenheim), Spain (Sevilla) and Sweden (Bor?s). They use the tested scalability and replication rules to reinforce their impacts on the five future city district refurbishment processes, thus showing that district renovation can be prepared under different sizes, climate and regulatory conditions (Scandinavia, Central Europe, Atlantic, and Mediterranean). A robust exploitation plan with a complete European perspective is then designed involving replication cluster cities and industry. '";43147381;27451972;FP7-SMARTCITIES-2013;/CP-SoU;RISE RESEARCH INSTITUTES OF SWEDEN AB;SE;"SOCIETA ELETTRICA ALTOATESINA PER AZIONI;BORAS KOMMUN;ZABALA INNOVATION CONSULTING, S.A.;TIROLER ZUKUNFTSSTIFTUNG;COMMUNE DE LA ROCHELLE;LIEBHERR-HAUSGERAETE LIENZ GMBH;COMUNE DI BOLZANO;ISTITUTO PER L'EDILIZIA SOCIALE DELLA PROVINCIA AUTONOMA DI BOLZANO;ALFA LAVAL CORPORATE AB;ACCADEMIA EUROPEA DI BOLZANO;MUNICIPALITY OF PAFOS;CORPORACION DE EMPRESAS MUNICIPALES DE SEVILLA AIE;NEUE HEIMAT TIROL GEMEINNUTZIGE WOHNUNGSGMBH;INNSBRUCKER KOMMUNALBETRIEBE AG;AGENZIA PER L'ENERGIA ALTO ADIGE -CASACLIMA;TIGAS-ERDGAS TIROL GMBH;UNIVERSITAET INNSBRUCK;DOWEL MANAGEMENT;LANDESHAUPTSTADT INNSBRUCK;STADT ROSENHEIM;INNSBRUCKER IMMOBILIEN GMBH & CO KG;WOLFGANG FEIST;CENTRE NATIONAL D EXPERTISE DE L ENVELOPPE ET DE LA STRUCTURE ASSOCIATION;GREENOVATE ! EUROPE";"IT;SE;ES;AT;FR;CY;DE;BE";"/ESV;/EST";1;0;0;1;0;0 108681;316310;CELIM;ONG;FP7-REGPOT;REGPOT-2012-2013-1;FP7;Fostering Excellence in Multiscale Cell Imaging;2013-06-01;2016-05-31;;The project (Fostering Excellence in Multiscale Cell Imaging - CELIM) is designed to energize the research potential of the University of P. J. Safarik in Kosice, Slovakia, by the enhancement of the existing network of collaborators with the selected excellent European Partners, centered around the theme of cell imaging and by the acquisition of a new technical infrastructure. The main goals and activities of the project can be summarized as follow: i) to integrate scientists with complementary research skills into a coherent interdisciplinary research entity, ii) to reinforce excellence and creativity of the scientists in consortium by the knowledge and know-how transfer from leading research European organizations, iii) to upgrade existing infrastructure for up-to-date experiments, iv) to identify and reintegrate skillful and experienced Slovak scientists. The realization of the project will result to the improvement of the research environment, substantial increase of competitiveness in the ERA, and ensure leadership of the consortium in the field of cell imaging in the region. The CELIM consortium is fully dedicated to promote application of the knowledge obtained in basic research into practice. The realization of the project will accelerate our research activities in the most promising areas of cell imaging (e.g. involvement of the consortium in the research program of the European XFEL experimental stations). The benefits of the foreseen progress in cell imaging will expand our current impact towards new horizons in oncology (selective drug targeting and effective cancer treatment), stem cells research (novel insights into human and animal morphogenesis), reproduction and animal breeding (development of non-invasive techniques for single-cell diagnosis). Thus, broad implications for not only the basic biomedical research, but also directly to practical sphere (e.g. cancer therapy and diagnosis, regenerative medicine and agriculture) can be expected.;2927874;2613937;FP7-REGPOT-2012-2013-1;/CSA-SA;UNIVERZITA PAVLA JOZEFA SAFARIKA V KOSICIACH;SK;;;/SCI;1;0;0;1;0;0 110663;335122;LIVHET;ONG;FP7-IDEAS-ERC;ERC-SG-LS2;FP7;Single cell heterogeneity in the mammalian liver;2013-11-01;2018-10-31;;"The mammalian liver performs critical functions for maintaining metabolic homeostasis. It regulates the body’s glucose and lipid stores, detoxifies blood, and produces bile among a host of other functions. The liver achieves this diversity through the collective behaviour of heterogeneous hepatocytes operating in highly structured microenvironments. Understanding the design principles of the liver is an open challenge requiring analysis of single cells within the intact tissue. Liver heterogeneity appears at two length scales. At the liver lobule level centripetal blood flow creates gradients of oxygen, nutrients and hormones. The consumption of hepatocytes along the lobule axis determines the inputs available for more centrally located hepatocytes. The resulting spatial division of labor, termed ‘liver zonation’ could enable optimal tissue function in face of these long-range constraints. At the cellular level most hepatocytes are polyploid cells, having either one or two nuclei and a corresponding variability in cell sizes. The functional advantage of liver polyploidy remains unclear. In this proposal we aim to combine single molecule transcript imaging in the intact liver with theory from systems biology to uncover the design principles of liver heterogeneity. We will examine the hypothesis that spatial zonation and hepatocyte polyploidy evolved to enable the liver to optimally operate. We will characterize the spatial co-expression patterns of key liver genes and theoretically compare the ability of these patterns to excel over alternative patterns. We will also characterize the differential resource allocation of hepatocytes of different ploidy classes. This interdisciplinary project stands at the forefront of research in mammalian biology, addressing fundamental properties of a major organ at unprecedented single-cell resolution. It will open new avenues for extending the field of systems biology to the analysis of complex tissues in mammalian organisms.";1500000;1500000;ERC-2013-StG;/ERC-SG;WEIZMANN INSTITUTE OF SCIENCE;IL;;;"/BIO;/LIF";1;0;0;1;0;0 111554;617337;QITBOX;ONG;FP7-IDEAS-ERC;ERC-CG-2013-PE2;FP7;Quantum Information Theory with black BOXes;2014-01-01;2018-12-31;;"'With QITBOX we aim to develop a novel device-independent framework for quantum information processing. In this framework, devices are seen as black boxes that only receive inputs and produce outputs. Our main objective is to understand what can and cannot be done for information processing using only the observed correlations among the devices. We will structure our effort along three main research lines: (i) Characterization of quantum correlations: the general objective will be to characterize those correlations that are possible among quantum devices; (ii) Protocols based on correlations: the general objective will be to understand how quantum correlations can be exploited in order to construct relevant information protocols and (iii) Applications to physical setups: here the previous results to concrete physical setups will be applied, such as the quantum-optical realizations of the protocols or the study of the non-local properties of many-body systems. The expected results of QITBOX are: (i) Novel methods for the characterization of quantum correlations, (ii) Improved or novel device-independent protocols, (iii) Proposals for feasible experimental implementations of these protocols and (iv) Novel methods for the study of many-body systems based on correlations. QITBOX is a highly-interdisciplinary project with implications in Physics, Mathematics, Computer Science and Engineering. The execution of the planned research work will provide a unifying framework for a Quantum Information Theory with black BOXes (hence the acronym). Such a framework will bring quantum information processing to an unprecedented level of abstraction, in which information protocols and primitives are defined without any reference to the internal physical working of the devices. This, in turn, will lead to much more robust practical implementations of quantum information protocols, closing the mismatch between theoretical requirements and experimental realisations.'";1487505;1487505;ERC-2013-CoG;/ERC-CG;FUNDACIO INSTITUT DE CIENCIES FOTONIQUES;ES;;;"/PSE;/SCI";1;0;0;1;0;0 110818;603502;DACCIWA;ONG;FP7-ENVIRONMENT;ENV.2013.6.1-2;FP7;Dynamics-aerosol-chemistry-cloud interactions in West Africa;2013-12-01;2018-11-30;;Massive economic and population growth and urbanisation are expected to lead to a tripling of anthropogenic emissions in southern West Africa (SWA) between 2000 and 2030, the impacts of which on human health, ecosystems, food security and the regional climate are largely unknown. An assessment of these impacts is complicated by (a) a superposition with effects of global climate change, (b) the strong dependence of SWA on the sensitive West African monsoon, (c) incomplete scientific understanding of interactions between emissions, clouds, radiation, precipitation and regional circulations and (d) by a lack of observations to advance our understanding and improve predictions. The DACCIWA project will conduct extensive fieldwork in SWA to collect high-quality observations, spanning the entire process chain from surface-based natural and anthropogenic emissions to impacts on health, ecosystems and climate. Combining the resulting benchmark dataset with a wide range of modelling activities will allow (a) to assess all relevant physical and chemical processes, (b) to improve the monitoring of climate and compositional parameters from space and (c) to develop the next generation of weather and climate models capable of representing coupled cloud-aerosol interactions, which will ultimately lead to reduced uncertainties in climate predictions. SWA with its rich mix of emissions and diverse clouds is ideal for such a study and many findings and technical developments will be applicable to other monsoon regions. Using a targeted dissemination strategy, DACCIWA will deliver a comprehensive scientific assessment and actively guide sustainable future planning and policy-making for West Africa and beyond. The interdisciplinary and experienced DACCIWA team will build on the scientific and logistical foundations established by AMMA (EU FP6) and collaborate closely with operational centres, international programs (e.g. WCRP, IGBP), policy-makers and users to maximise impact.;11508227,29;8746951,77;FP7-ENV-2013-two-stage;/CP;KARLSRUHER INSTITUT FUER TECHNOLOGIE;DE;"UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6;UNIVERSITE PARIS DIDEROT - PARIS 7;THE UNIVERSITY OF MANCHESTER;UNIVERSITE CLERMONT AUVERGNE;THE UNIVERSITY OF READING;MET OFFICE;Kwame Nkrumah University of Science and Technology Kumasi;OBAFEMI AWOLOWO UNIVERSITY;UNIVERSITY OF LEEDS;UNIVERSITE BLAISE PASCAL CLERMONT-FERRAND II;DEUTSCHES ZENTRUM FUER LUFT - UND RAUMFAHRT EV;UNIVERSITY OF YORK;EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH;EUROPEAN CENTRE FOR MEDIUM-RANGE WEATHER FORECASTS;UNIVERSITE PAUL SABATIER TOULOUSE III;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS";"FR;UK;GH;NG;DE;CH";/ENV;1;0;0;1;0;0 110072;602805;AGGRESSOTYPE;ONG;FP7-HEALTH;HEALTH.2013.2.2.1-3;FP7;Aggression subtyping for improved insight and treatment innovation in psychiatric disorders;2013-11-01;2018-10-31;https://www.aggressotype.eu/;"Aggression is a basic physiological trait with important roles throughout evolution, both in defence and predation. When expressed in humans in the wrong context, aggression leads to maladjustment, social impairment and crime. Despite this, knowledge about aggression aetiology is limited and current treatment strategies are insufficient. Contingent to a subdivision into impulsive and instrumental subtypes, we investigate the aetiology of maladaptive aggression in paediatric conduct disorders most strongly predisposing to pathological aggression, ADHD and conduct disorder, and in the general population. We employ highly innovative approaches in humans and animal models and maximize the output from the project by optimally balancing the use of large, existing data sets with new data acquisition. Through this, we build a knowledge chain from molecule to behaviour, investigating known and novel genes, gene-networks and their epigenetic interactions, and mapping their mode of action from the molecular via the cellular to the brain-circuit level. This is accompanied by highly powered analyses of the neural substrates of the aggression subtypes. Based on innovative bioinformatic multimodal data integration, our interdisciplinary research will lead to novel, accurate algorithms for reliable aggression prediction, which will be validated in existing longitudinal studies in children and tested for their predictive value in adult outcome. In addition to this approach towards prevention, we test promising non-pharmacological biofeedback for personalised treatment and prevention of overt aggression. For the identification of novel pharmacological compounds in aggression treatment, we introduce a new animal model, the zebrafish. The Aggressotype consortium is based on successful existing collaborations. It includes experts in childhood and adult psychiatry and research-intensive SMEs ensuring maximal dissemination, clinical implementation and business development opportunities.";7863780,82;6000000;FP7-HEALTH-2013-INNOVATION-1;/CP-FP;STICHTING KATHOLIEKE UNIVERSITEIT;NL;"AARHUS UNIVERSITET;GENOWAY S.A.;GENALICE BV;TARTU ULIKOOL;UNIVERSITAETSKLINIKUM WUERZBURG - KLINIKUM DER BAYERISCHEN JULIUS-MAXIMILIANS-UNIVERSITAT;STATENS SERUM INSTITUT;UNIVERSITAET ULM;UNIVERSITY OF DUNDEE;ACADEMISCH ZIEKENHUIS GRONINGEN;UNIVERSITEIT MAASTRICHT;ISLENSK ERFDAGREINING EHF;SERVICIO MADRILENO DE SALUD;UNIVERSITAT ZURICH;CONSORCI INSTITUT D'INVESTIGACIONS BIOMEDIQUES AUGUST PI I SUNYER;UNIVERSITAT DE BARCELONA;JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN;THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK;UNIVERSITY OF LEICESTER;ZENTRALINSTITUT FUER SEELISCHE GESUNDHEIT;FUNDACIO HOSPITAL UNIVERSITARI VALL D'HEBRON - INSTITUT DE RECERCA;Concentris Research Management GmbH;OSPEDALE PEDIATRICO BAMBINO GESU;UNIVERSITETET I BERGEN;VIEW POINT SA;KING'S COLLEGE LONDON";"DK;FR;NL;EE;DE;UK;IS;ES;CH;US;IT;NO";/LIF;1;0;0;1;0;0 111441;609412;DIFeREns2;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-COFUND;FP7;Durham International Fellowships for Research and Enterprise;2014-10-01;2019-09-30;;"The Durham International Fellowships for Research and Enterprise (DIFeREns2) will greatly expand and enhance a successful COFUNDed fellowship scheme at Durham University. DIFeREns2 will provide fellowships across all areas of the natural sciences, social sciences and the humanities for both early-career and established researchers seeking to address challenging problems in the 10 interdisciplinary Research Institutes and more than 50 Research Centres within the University. The Colleges of Durham University will accommodate the Senior Fellows and enrol the Junior Fellows into their welcoming intellectual community. The renowned Institute of Advanced Study (IAS), situated within the World Heritage Site around Durham Cathedral, will administer the Fellowship Scheme and act as a focus for cohort-building activities and a locus for Fellows to meet and interact. The IAS hosts the University’s signature IAS Fellowship Scheme, which brings together 20 Fellows each year from across all academic disciplines and the creative arts to work together on an annual theme. The Junior Research Fellowship scheme aims to attract early-career researchers of the highest calibre from around the world, who wish to undertake a substantial research project for a period of 1-3 years. JRFs are full employees of Durham University. DIFeREns2 will enhance our existing JRF scheme by including an outgoing phase for up to 25% of the Fellowship to stimulate network building and trans-national mobility, as well as generous research expenses and new personal development opportunities in the Colleges. There will be two types of Senior Fellowships: Senior Research Fellowships for leading international researchers, and Policy and Enterprise Fellowships for practitioners in industry, government, NGOs or cultural organisations, who will engage with the application of research in Durham. Intersectoral mobility is a central theme of both the Policy and Enterprise Fellowships and the IAS Fellowships.";19214382;7685752,8;FP7-PEOPLE-2013-COFUND;/MC-COFUND;UNIVERSITY OF DURHAM;UK;;;/LIF;1;0;0;1;0;0 111555;617472;SLIDEQUAKE;ONG;FP7-IDEAS-ERC;ERC-CG-2013-PE10;FP7;Detection and understanding of landslides by observing and modelling gravitational flows and generated earthquakes;2014-05-01;2019-04-30;;"The goal of the project is to take a major step in improving the detection and understanding of landslides and their modelling at the field scale through the analysis of generated seismic waves. The seismic signal generated by landslides (i. e. landquakes) provides a unique tool to estimate the properties of the flow and its dynamics. Indeed, the stress applied by the landslide to the ground, which generates seismic waves, is highly sensitive to the flow history and therefore to the physical properties during mass emplacement. The strategy will be to combine a very accurate description of the landslide source, and the simulation and measurements of landquakes from the laboratory to the natural scale, by leading an ambitious interdisciplinary project involving numerical modelling, laboratory experiments and observation. The methodology will be to (1) develop thin layer models for granular flows over a complex 3D topography to alleviate the high computational costs related to the description of the real topography, taking into account the static/flowing transition and the fluid/grains mixture, both playing a key role in natural flows; (2) simulate the generated seismic waves by coupling landslide models to state-of-the-art wave propagation models. An ambitious objective will be to develop efficient coupling methods; (3) develop laboratory experiments of seismic emissions generated by granular flows to test the models and understand the physical processes at work; (4) analyse, simulate and invert natural landquakes making use of underexploited high-quality seismic and geomorphological data, in particular on volcanoes. An ultimate objective will be to design a new generation of landslides models, reliable methods and operational tools for detection of gravitational flows, and interpretation of seismic data in terms of landslide properties. This tools will be transferred to the scientific community and to the observatories in charge of monitoring landslide activity.";1999240,8;1999240,8;ERC-2013-CoG;/ERC-CG;INSTITUT DE PHYSIQUE DU GLOBE DE PARIS;FR;;;"/PSE;/SCI;/EAR";1;0;0;1;0;0 105651;313642;LASI;ONG;FP7-IDEAS-ERC;ERC-SG-SH2;FP7;Law, science and interests in European policy-making;2013-01-01;2018-06-30;;"This project provides a detailed analysis of how European law structures the use of different types of expertise in European policy-making, and assesses whether and to what extent objectives such as ensuring scientific expertise, sound evidence and interest representation overlap or are in tension with each other. However, European law constitutes a particular social subsystem, a cognitive framework and a form of expertise. While law is expected to deliver the regulatory framework through which different types of expertise are incorporated into European policy-making, it is itself framed through a process in which different types of expertise play a role. This research project has therefore two objectives. Objective 1: Mapping and critically assessing the European legal framework that structures different types of expertise in European policy-making. Objective 2: Analysing how European law functions as a social subsystem and assessing how legal expertise functions in relation to other forms of expertise in European policy-making. While the project is inspired by legal theory, and in particular systems theory and reflexive law theory, it employs an interdisciplinary methodology ensuring a detailed empirical enquiry based on legal analysis, semi-structured elite interviews, process tracing of adopted policy measures, and network analysis. The project focuses on three policy areas that feature very different modes of European governance, namely nano-technology, employment, and competition policy.";1453748;1453748;ERC-2012-StG_20111124;/ERC-SG;CARDIFF UNIVERSITY;UK;;;/SOC;1;0;0;1;0;0 109308;323861;BRONZEAGETIN;ONG;FP7-IDEAS-ERC;ERC-AG-SH6;FP7;Tin Isotopes and the Sources of Bronze Age Tin in the Old World;2013-08-01;2018-07-31;;"'This multidisciplinary project comprising archaeology, history, geochemistry, and geology aims at the decipherment of the enigma of the origin of a material that emerged in the third millennium BCE and gave an entire cultural epoch its name, namely the alloy of copper and tin called bronze. While copper deposits are relatively widely distributed there are only very few tin deposits known in the Old World (Europe, the Mediterranean basin and southwest Asia). Since the late 19th century archaeologists have discussed the question of the provenance of tin for the production of the earliest bronzes without any definite answer. The enigma has even grown over the past decades, because it turned out that the earliest bronzes appear in a wide area stretching from the Aegean to the Persian Gulf that is geologically devoid of any tin deposits. There is tin in western and central Europe and there is also tin in central Asia. Thus, tin or bronze seems to have been traded over large distances but it is unknown in which direction. Now a new method has become available that offers the chance to trace ancient tin via tin isotope signatures. It was found that the isotope ratios of tin exhibit small but measurable variations in nature making different tin deposits identifiable so that bronze objects can in principle be related to specific ore deposits. It is proposed to apply for the first time this new technology to characterize all known tin deposits in the Old World and relate them to bronze and tin artefacts of the third and second millennia BCE. This groundbreaking interdisciplinary study will increase our understanding of Bronze Age metal trade beyond surmise and speculation with vast implications for the reconstruction of socio-economic relations within and between Bronze Age societies. The impact will be a major advance in our understanding of the earliest complex societies with craft specialization and the formation of cities and empires.'";2340800;2340800;ERC-2012-ADG_20120411;/ERC-AG;RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG;DE;CURT-ENGELHORN ZENTRUM ARCHAOMETRIEGGMBH-CEZA;DE;/SOC;1;0;0;1;0;0 105366;306488;SLIM;ONG;FP7-IDEAS-ERC;ERC-SG-PE10;FP7;Strain Localisation in Magma;2012-10-01;2018-06-30;;"The tendency of geomaterials to localise deformation is a measure of “the fragility of the Earth” – a threshold to the occurrence of geological hazards. At volcanoes, the remarkable, unpredictable and alarming occurrence of eruptions, switching from low-risk effusive to high-risk explosive eruptive behaviour is a direct consequence of strain localisation in magma (SLiM). A deformation mechanism map of magma subjected to strain localisation will allow numerical models with higher accuracy, which, coupled to an understanding of the mechanics driving the monitored geophysical signals precursor to failure, will enhance eruption forecasts. We propose a truly innovative and interdisciplinary approach to a description of SLiM. This collaborative study will pioneer in the integration of efforts from field geologists, experimentalist, mineralogists, petrologists, seismologists, and numerical modellers to underline the effects of microscopic processes responsible for the large-scale impacts of strain localisation in magma during transport and eruption.";1908000;1908000;ERC-2012-StG_20111012;/ERC-SG;THE UNIVERSITY OF LIVERPOOL;UK;;;"/PSE;/ENV;/EAR";1;0;0;1;0;0 101616;291141;CHEMPLAN;ONG;FP7-IDEAS-ERC;ERC-AG-PE9;FP7;Astrochemistry and the Origin of Planetary Systems;2012-07-01;2018-06-30;;"When interstellar clouds collapse to form new stars and planets, the surrounding gas and dust become part of the infalling envelopes and rotating disks, thus providing the basic material from which new solar systems are made. Instrumentation to probe the physics and chemistry in low-mass star-forming regions has so far lacked spatial resolution. I propose here an integrated observational-modeling-laboratory program to survey protostars and disks on the relevant scales of 1-50 AU where planet formation takes place. The observations are centered on new data coming from the Atacama Large Millimeter / submillimeter Array (ALMA), and the analysis includes unique new data from key programs on Herschel, Spitzer and VLT that I am (co-)leading. The combination of millimeter and infrared data allows the full range of temperatures from 10-2000 K in star- and planet- forming regions to be probed, for both gas and solids. The molecular line data are used as diagnostics of physical parameters (such as UV field, cosmic ray ionization rate, kinematics, mixing, shock strength, grain growth, gas/dust ratios) as well as to follow the chemistry of water and complex organic molecules from cores to disks, which ultimately may be delivered to terrestrial planets. The implications for the history of volatile material in our own solar systen and exo-planetary atmospheres will be assessed by comparing models and data with cometary taxonomy and, ultimately, feeding them into planet population synthesis models. Altogether, this program will bring the link between interstellar chemistry and solar system and exo-planetary research to a new level. The project will train four PhD students in a truly interdisciplinary environment in which they are exposed to all aspects of molecular astrophysics and have access to ample ALMA expertise, and it will prepare two postdocs for future faculty positions.";2499150;2499150;ERC-2011-ADG_20110209;/ERC-AG;UNIVERSITEIT LEIDEN;NL;;;"/PSE;/AER;/SPA";1;0;0;1;0;0 99806;288263;NANO-VISTA;ONG;FP7-ICT;ICT-2011.3.5;FP7;Advanced photonic antenna tools for biosensing and cellular nanoimaging;2011-11-01;2016-10-31;;"Advances in the fields of molecular and cell biology are strongly coupled to the implementation of photonic tools that allow highly-sensitive measurements in living cells at high molecular concentrations and at the nanometre scale. The goal of NANO-VISTA is to exploit novel concepts of photonic antennas to develop a new generation of bionanophotonic tools for ultrasensitive detection, nanoimaging and nanospectroscopy of biomolecules, both in-vitro and in living cells. By taking advantage of the extraordinary field enhancement, directionality and nanofocusing of photonic antennas, our approach will allow single biomolecule detection in ultra-reduced detection volumes, including living cells. The project focuses on three main objectives: a) to pioneer the development of novel photonic antennas for ultrasensitive detection in fluids and simultaneous spatio-temporal superresolution in living cells; b) to develop high-throughput large-scale nanofabrication of photonic antennas fully compatible with life science applications; c) to demonstrate the functionality of the technology for biosensing and transferability into potential market products, and for nanoimaging and nanospectroscopy on living cells. Thus, NANO-VISTA is fully targeted to the development of disruptive photonic technologies fundamental in strategic applications such as medicine and biology. To maximise the chances of success we have chosen for an interdisciplinary, trans-national and multi-institutional partnership (including a SME and a Medical Centre). True European specialists, with long standing expertise in the fields of nanophotonics, photonic antennas, large-scale nanofabrication approaches and nanoimmunologists are concentrated in this proposal strengthening European research cohesion. In the mid-long term we expect that both, cell biologists as well as industrial sectors (biophotonic, microscopy and biotechnology enterprises) will benefit from this new technology";4049511;3020000;FP7-ICT-2011-7;/CP;FUNDACIO INSTITUT DE CIENCIES FOTONIQUES;ES;"STICHTING KATHOLIEKE UNIVERSITEIT;PIXINBIO SAS;FUNDACIO INSTITUT DE BIOENGINYERIA DE CATALUNYA;ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;Imagine Optic Spain S.L.";"NL;FR;ES;CH";"/FUS;/FIS;/EST";1;0;0;1;0;0 99306;284953;SMARTV2G;CLO;FP7-ICT;GC-ICT-2011.6.8;FP7;Smart Vehicle to Grid Interface;2011-06-01;2014-05-31;;In a context of an obliged continuous optimisation of the energy consumption rates in developed societies, embedded systems and solutions can perform a significant role in the transition process towards a Sustainable Urban Life concept in European countries. One of the main and most promising technological areas that are expected to be able to contribute in a most relevant way to that overall target is the one constituted by the electric vehicles.
In that sense, the main objective targeted by the SMARTV2G Project aims at connecting the electric vehicle to the grid by enabling controlled flow of energy and power through safe, secure, energy efficient and convenient transfer of electricity and data.
This will entail, among other specific objectives, the development of a new generation of technologies allowing the seamless and user-friendly energy load of electric vehicles in urban environments in the frame of an intelligent energy supply network managed by an embedded control system.
In order to be able to achieve the exposed objectives, the project Consortium is comprised of a well-balanced group of 7 partners from 4 European countries with complementary skills and expertise, including all the necessary profiles to deal with the scheduled project work plan. Furthermore, key industrial companies in the field of electro-mobility have shown their interest and commitment to the project.
This interdisciplinary group of the energy industry, alternative energy components developers, software & embedded systems developers, and technological R&D centres are strongly committed to efficiently coordinate their resources over the 36 months duration of the project in order to be able to reach all expected project outcomes.;3279368;2520000;FP7-2011-ICT-GC;/CP;ASOCIACION INSTITUTO TECNOLOGICO DE LA ENERGIA;ES;"ETREL SVETOVANJE IN DRUGE STORITVE DOO;TECHNOMAR GMBH;ELEKTRO LJUBLJANA PODJETJE ZADISTRIBUCIJO ELEKTRICNE ENERGIJE D.D.;FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.;CIT DEVELOPMENT S.L.;UNIVERSITA DEGLI STUDI DI ROMA LA SAPIENZA";"SI;DE;ES;IT";/ESV;1;0;0;1;0;0 97732;270108;Goal-Leaders;CLO;FP7-ICT;ICT-2009.2.1;FP7;Goal-directed, Adaptive Builder Robots;2011-03-01;2014-02-28;;"The Goal-Leaders project aims at developing biologically-constrained architectures for the next generation of adaptive service robots, with unprecedented levels of goal-directedness and proactivity. Goal-Leaders will realize builder robots able to realize externally assigned tasks (e.g., fetching objects, composing building parts) and, at the same time, keeping their homeostatic drives within a safe range (e.g., never end up without energy or get hurt), by operating autonomously and for prolonged periods of time in open-ended environments. To this aim, Goal-Leaders will pursue a combined neuroscientific, computational and robotic study of three key sets of competences:-the biological and computational mechanisms behind an agent's goal system, which integrates somatic, affective, and cognitive elements, and realizes the setting and selection of the agent's goals;-the biological and computational mechanisms that support the assignment of situation-dependent value to an agent's state and action representations, and therefore realize the link between the agent's goal system and perceptual-motor processes;-the biological and computational mechanisms behind an agent's anticipatory and mental simulation abilities.The Goal-Leaders achievements beyond the state of the art will be assessed against behavioral and neuroscientific data, and by realizing three demonstrators in which robots will perform autonomous navigation and construction tasks, and will readapt without reprogramming to novel task allocations or changes in their environment.The project consortium includes a highly complementary, interdisciplinary team of top European researchers who focus on neuroscience, cognitive science, and robotics. Our robotic design methodology will have a significant impact both for the understanding of goal-directed action in living organisms, and for the realization of goal-directed service robots by combining navigation and manipulation within an unconstrained environment.";2357421;1800000;FP7-ICT-2009-6;/CP;CONSIGLIO NAZIONALE DELLE RICERCHE;IT;"UNIVERSIDAD POMPEU FABRA;LUNDS UNIVERSITET;UNIVERSITEIT VAN AMSTERDAM";"ES;SE;NL";"/ROB;/NET";1;0;0;1;0;0 97676;270019;SpaceBook;CLO;FP7-ICT;ICT-2009.2.1;FP7;Spatial & Personal Adaptive Communication Environment: Behaviors & Objects & Operations & Knowledge;2011-03-01;2014-04-30;;The SpaceBook project will prototype a speech-driven, hands-free, eyes-free device for pedestrian navigation and exploration. SpaceBook will be developed as open source and progress will be bench marked through controlled task-based experiments with real users in central Edinburgh. The SpaceBook project will generate concrete technical and scientific advances for eyes-free, hands-free navigation and exploration systems which will support applications in tourism, elderly care and tools for urban workers.
In addition to advances in navigation and exploration systems, SpaceBook provides a task environment in which more fundamental scientific and technical knowledge will be generated. Specifically we seek to advance the state of the art in model-based approaches to plan generation and recognition, statistical learning techniques for interaction management and machine learning of semantic analysis components.
The interdisciplinary SpaceBook team brings a wealth of complementary expertise necessary to realize the SpaceBoook vision. Ume? University (Sweden), the project's overall coordinator, brings expertise in natural language interfaces to database systems and spatial databases. The University of Edinburgh (UK) brings expertise in location-based services, dynamic 3D modelling, geographical information systems, system evaluation methodology, discourse processing, and information access and delivery (including question answering). Heriot Watt University (UK) brings experience in machine learning, spoken dialogue systems, data-collection, and evaluation of interactive systems. KTH (Sweden) brings expertise in dialogue management and the design and development of spoken dialogue systems. Our industrial partner, Liquid Media (Sweden), brings software engineering and commercial exploitation expertise and experience. Cambridge University (UK) brings expertise in the combination of linguistic theory and machine learning and the development of real-world language processing applications. Finally, the AI group from the Universitat Pompeu Fabra (Spain) brings expertise in the areas of autonomous behavior, and in particular, model-based methods for plan generation and plan recognition.;3674051;2799551;FP7-ICT-2009-6;/CP;UMEA UNIVERSITET;SE;"UNIVERSIDAD POMPEU FABRA;THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;KUNGLIGA TEKNISKA HOEGSKOLAN;HERIOT-WATT UNIVERSITY;LIQUID MEDIA AB;THE UNIVERSITY OF EDINBURGH";"ES;UK;SE";"/ROB;/NET";1;0;0;1;0;0 97574;270483;FOCUS;CLO;FP7-ICT;ICT-2009.8.7;FP7;Single Molecule Activation and Computing;2011-01-01;2014-03-31;;"The present project, FOCUS, will build a novel generation of biologically inspired molecular devices (MDs) based on the developments of new photonic tools. These photonic tools will use Plasmon Polariton and two-photon technology, enabling focused light spots with a diameter around 10 nm. FOCUS will also develop new light sensitive molecules that will be selectively activated by our new photonic tools. These new technological innovations will provide a way to control activation of single light sensitive molecules and will allow the investigation of molecular computation in a biological environment and with an unprecedented resolution. On the basis of these investigations and by using the developed new tools, FOCUS will design and test new MDs for amplification and information processing. FOCUS will: i - provide new photonic devices to control single molecules; ii – lay out the basis for understanding molecular computation in biological systems; iii - provide proofs of concept and suggestions for designing new molecular artificial computing systems; iv- build prototypes of these new MDs. FOCUS has formed a highly interdisciplinary consortium composed of nanotechnologists able to fabricate the new photonic devices - i.e. Enzo Di Fabrizio (IIT), Alpan Bek (METU) and Marco Lazzarino (CBM), chemists able to develop the photoswitches and assemble the MDs – i.e. Pau Gorostiza (IBEC) and Ljiljana Fruk (KIT) and biologists able to understand molecular mechanisms – i.e. Vincent Torre (SISSA) and Fabio Benfenati (IIT). The two companies RappOptoElectronic and NT-MDT Europe BV will transform the new tools and devices into marketable products.";4322845;3174259;FP7-ICT-2009-6;/CP;SCUOLA INTERNAZIONALE SUPERIORE DI STUDI AVANZATI DI TRIESTE;IT;"NT-MDT Europe BV;FUNDACIO INSTITUT DE BIOENGINYERIA DE CATALUNYA;FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA;KARLSRUHER INSTITUT FUER TECHNOLOGIE;CONSORZIO PER IL CENTRO DI BIOMEDICINA MOLECOLARE SCARL;MIDDLE EAST TECHNICAL UNIVERSITY;RAPP OPTOELECTRONIC GMBH";"NL;ES;IT;DE;TR";/TEC;1;0;0;1;0;0 97182;270198;CHESS;CLO;FP7-ICT;ICT-2009.4.1;FP7;Cultural Heritage Experiences through Socio-personal interactions and Storytelling;2011-02-01;2014-03-31;;"Cultural heritage institutions nowadays face the important challenge of making their collections more engaging to visitors, especially the young 'digital natives', while exploiting, in new forms of cultural interactive experiences, the recently developed digital libraries. An approach for cultural heritage institutions (e.g. museums) would be to capitalize on the pervasive use of interactive digital content and systems in order to offer experiences that connect to their visitors' interests, needs, dreams, familiar faces or places; in other words, to the personal narratives they carry with them and, implicitly or explicitly, build when visiting a cultural site.
The principal objective of CHESS is to research, implement and evaluate an innovative conceptual and technological framework that will enable both the experiencing of personalised interactive stories for visitors of cultural sites and their authoring by the cultural content experts. Essentially, CHESS proposes to create narrative-driven cultural 'adventures' through hybrid structures, which adapt continuously to their visitors, extend over space and time, and involve multiple users with different interfaces. To achieve this, CHESS will integrate interdisciplinary research in personalization and adaptivity, digital storytelling, interaction methodologies, and narrative-oriented mobile and mixed reality technologies, with a sound theoretical basis in the museological, cognitive, and learning sciences. This tightly integrated framework will be applied and tested in different types of cultural heritage sites; most notably two world-renowned museums, the New Acropolis Museum, and the Cité de l'Espace in France. Access to end-users will be further enhanced through the international User Group, a diverse body of cultural institutions and organisations.";4240041;2859712;FP7-ICT-2009-6;/CP;DIGINEXT;FR;"MOUSEIO AKROPOLIS;SOCIETE D'ECONOMIE MIXTE D'EXPLOITATION DE CENTRES CULTUREL EDUCATIF ET DE LOISIRS SEM;ETHNIKO KAI KAPODISTRIAKO PANEPISTIMIO ATHINON;FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.;REAL FUSIO FRANCE SAS;THE UNIVERSITY OF NOTTINGHAM";"EL;FR;DE;UK";"/INF;/ITT";1;0;0;1;0;0 95597;257886;ARISTOTELE;CLO;FP7-ICT;ICT-2009.4.2;FP7;Personalised Learning & Collaborative Working Environments Fostering Social Creativity and Innovations Inside the Organisations;2010-07-01;2013-12-31;;ARISTOTELE will enhance learning and training of the workers within their organisations defining and developing models, methodologies, technologies and tools to support the emergence of competences and creativity by self-organizing acquisition, processing and sharing of new information and knowledge with peers.To achieve this ARISTOTELE will design and develop a prototype platform presenting, as key differentiators, capabilities to support: i) creation and execution of personalised learning activities supporting an hybrid (adaptive and non-adaptive) strategy, ii) innovation building and management processes and iii) collaborative knowledge exploitation and acquisition during the daily worker activities. Human factors such as motivation to collaborate and share knowledge and innovative ideas within organisations will be considered and addressed in the designing and developing of the ARISTOTELE platform, including adoption inside organisations.The core of the solution starts from an already existing platform for the on-demand creation of personalised and adaptive Learning Experiences, based on suitable domains, learner models and didactical strategies, that will be extended in terms of models, methodology and functionalities towards the organisation, together with the integration, cooperation and covering of other related organisational issues like Knowledge Management, Human Resource Management and innovation management.Several challenging and interdisciplinary research themes are concerned with the project such as didactic modelling, collaborative innovation and working environments, knowledge management and discovery, collective intelligence, adaptive and non adaptive learning strategies.The project enables substantial improvements with respect to the state-of-the-art in the specific areas mentioned before, taking into account the results in the area of adaptive learning, organisational learning considering also the main EC projects on TEL approved.;6358202;4549600;FP7-ICT-2009-5;/CP;CENTRO DI RICERCA IN MATEMATICA PURA ED APPLICATA - CONSORZIO;IT;"MO.M.A. S.R.L. - MODELLI MATEMATICI ED APPLICAZIONI - MOMA;PUBLICIS HEALTHCARE COMMUNICATIONS GROUP SRL;AMIS DRUZBA ZA TELEKOMUNIKACIJE D.O.O.;UNIVERSITAET DUISBURG-ESSEN;HEALTHWARE SPA - PHI;MOMA SPA;UNIVERSITA DEGLI STUDI DI MILANO;ENGINEERING - INGEGNERIA INFORMATICA SPA;UNIVERSITAET INNSBRUCK";"IT;SI;DE;AT";"/EDU;/ITT";1;0;0;1;0;0 94730;257695;VERE;CLO;FP7-ICT;ICT-2009.8.4;FP7;Virtual Embodiment and Robotic Re-Embodiment;2010-06-01;2015-12-31;;VERE aims to carry out research on the fusion of the human body with virtual or physical surrogates. By fuse we mean that human participants would operate under the illusion that the virtual body is their own, or that they are actually in the physical space of the real world in a robotic body that they perceive as their own. As well as providing a radical extension of traditional virtual reality through the notion of virtual body ownership, VERE would pioneer remote body ownership, that is where the participant stays in a reclining and immobile position but operates a virtual or physical remote body via a brain and body computer interface (BBCI). This BBCI uses real-time EEG and other physiological data to infer participant intentions, and exploits machine learning to drive the virtual or robotic body. Two exemplary applications would be developed during the research: one in the context of gender-based domestic violence and the other to give physically impaired people such as tetraplegics the ability to operate again in the physical world through their surrogate. Both applications will be with domain professionals. There would be up to two further applications during the course of the project, managed by external groups who would submit proposals to the VERE consortium to exploit the technology for other unforeseen applications. The proposal is organised as eight scientific workpackages underpinned by one on the science of body ownership led by a team of cognitive neuroscientists. The work is informed by consideration of its ethical implications, and provides a testing ground for experiments in neuroethics. Moreover the work clearly has implications for the notion of self and consciousness, and one WP will be devoted to these issues. The proposal has been formed by a highly interdisciplinary group. It also draws on earlier FET projects IMMERSENCE and PRESENCCIA but opens the door to a radically new form of human-computer confluence with beneficial applications.;12429481;9498000;FP7-ICT-2009-5;/CP;UNIVERSITAT DE BARCELONA;ES;"Instituto de Telecomunicaç?es;Institute of Mechanics, Bulgarian Academy of Sciences;JOHANNES GUTENBERG-UNIVERSITAT MAINZ;GUGER TECHNOLOGIES OG;WEIZMANN INSTITUTE OF SCIENCE;TECHNISCHE UNIVERSITAET MUENCHEN;GUGER TECHNOLOGIES OEG;ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE;SCUOLA SUPERIORE DI STUDI UNIVERSITARI E DI PERFEZIONAMENTO SANT'ANNA;UNIVERSITY OF THE WEST OF ENGLAND, BRISTOL;CONSORCI INSTITUT D'INVESTIGACIONS BIOMEDIQUES AUGUST PI I SUNYER;UNIVERSITE MONTPELLIER 2 SCIENCES ET TECHNIQUES;UNIVERSITY COLLEGE LONDON;INTERDISCIPLINARY CENTER (IDC) HERZLIYA;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FONDAZIONE SANTA LUCIA";"PT;BG;DE;AT;IL;CH;IT;UK;ES;FR";"/LIF;/ICT;/IPS;/INF";1;0;0;1;0;0 93753;248828;ADVANCE;CLO;FP7-ICT;ICT-2009.3.6;FP7;Asynchronous and Dynamic Virtualisation through performance ANalysis \nto support Concurrency Engineering;2010-02-01;2013-09-30;;Multi-core/many-core systems offer potential both for cheap, scalable high-performance computing and also for significant reductions in power consumption compared with conventional processor technologies. At the same time, cores are becoming increasingly complex and heterogeneous. While current programming technologies are (just) coping with thesmall-scale homogeneous dual-core and quad-core processors available today, new programming paradigms are needed to deal with the massivenumbers of heterogeneous cores that will become available in future.
The ADVANCE project will tackle this important problem by developing a new and advancedcost-directed \\emph{hardware virtualisation} technology to map programs onto emerging hardware architectures in a way that is both flexible and transparent to the programmer, but which, nevertheless, respects the programmers' expectations and requirements on extra-functional properties, such as resource utilisation or power consumption. This interdisciplinary project will exploit leading work on computer architecture, probabilistic resource usage analysis, heuristic placement and mapping, programming languages and compilation methods to develop new cost-directed stream-processing models for parallel execution,and to apply these to commercial problems taken from a range of sectors: enterprise business software, image/voice/video processing, computational healthcare, etc.;4528988;3106998;FP7-ICT-2009-4;/CP;THE UNIVERSITY OF HERTFORDSHIRE HIGHER EDUCATION CORPORATION;UK;"SAP SE;UNIVERSITEIT TWENTE;THE UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS;SOFTWARE COMPETENCE CENTER HAGENBERG GMBH;HERIOT-WATT UNIVERSITY;TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY;BioID GmbH;PHILIPS MEDICAL SYSTEMS NEDERLAND BV;UNIVERSITEIT VAN AMSTERDAM";"DE;NL;UK;AT;IL";/IPS;1;0;0;1;0;0 93065;243914;BRAIN-I-NETS;CLO;FP7-ICT;ICT-2007.8.0;FP7;Novel Brain-Inspired Learning Paradigms for Large-Scale Neuronal Networks;2010-01-01;2012-12-31;;Current designs of neurally inspired computing systems rely on learning rules that appear to be insufficient to port the superior adaptive and computational capabilities of biological neural systems into large-scale recurrent neural hardware system. This is not surprising, since most of these learning rules had to be extrapolated from results of neurobiological experiments in vitro. New experimental techniques in neurobiology - such as 2-photon laser-scanning microscopy, optogenetic cell activation, and dynamic clamp techniques - make it now possible to record the changes that really take place in the intact brain during learning. First results indicate that the rules for synaptic plasticity have in fact to be rewritten. In particular, it appears that local synaptic plasticity is gated in multiple ways by global factors such as neuromodulators and network states. One primary goal of this project is to apply and extend new cutting-edge experimental techniques to produce a set of rules for synaptic plasticity and network reorganisation that describe the actual adaptive processes that take place in the living brain during learning.These new rules will be analysed by computational neuroscience experts and their consequences for learning in simulated large-scale networks of neurons and neurally inspired computing systems will be ascertained. The goal of this project is to port essential aspects of learning in the intact brain into current and next-generation neuromorphic hardware. New interchangeable software tools, that have recently been developed in the FP6 project FACETS, will be employed to carry out these investigations. Open questions that arise in these modelling studies will be addressed by changes in experimental protocols of the neuroscientists, building on long standing interdisciplinary collaborations among the partners.;2629554;1998408;FP7-ICT-2009-C;/CP;TECHNISCHE UNIVERSITAET GRAZ;AT;"RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG;ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE;UNIVERSITAT ZURICH;UNIVERSITY COLLEGE LONDON;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING MCGILL UNIVERSITY";"DE;CH;UK;FR;CA";"/ELM;/IPS;/TEL";1;0;0;1;0;0 91507;245410;MODAP;CLO;FP7-ICT;ICT-2009.8.0;FP7;Mobility, Data Mining, and Privacy;2009-09-01;2013-02-28;;With the advance and wide usage of GPS enabled devices and other positioning systems, mobility behaviour of individuals can now be captured and streamed into a data warehouse for online or historical data analysis. We refer to such data as mobility data. Mobility data mining comes into picture as an emerging field which aims to extract knowledge from mobility data with a lot of opportunities as well as risks. The risks arise from the fact that, the mobility data is mostly about people, where they have been, at what times, how often, and with whom. Therefore privacy is a major concern, and needs to be addressed before the opportunities of mobility data mining can be harvested. MODAP aims to stimulate an interdisciplinary research area combining a variety of disciplines such as data mining, geography, visualization, data/knowledge representation, and transforming them into a new context of mobility while considering privacy which is the social aspect of this project. The high impact of MODAP is mainly due to the two related facets of its area of interest, i.e., people's movement behaviour, and the associated privacy implications. Privacy is often associated with the negative impact of technology, especially with recent scandals in the US such as AOL's data release which had a lot of media coverage. MODAP aims to turn this negative impact into positive impact by showing that privacy technology can be integrated into mobility data mining which is a challenging task. This very aim of MODAP also imposes a high risk, since nobody knows what kinds of privacy threats exist due to mobility data and how such data can be linked to other data sources.;1101707;975266;FP7-ICT-2009-C;/CSA;SABANCI UNIVERSITESI;TR;"UNIVERSITEIT HASSELT;WIND TELECOMUNICAZIONI S.P.A.;UNIVERSITE DE LAUSANNE;ETHNIKO KAI KAPODISTRIAKO PANEPISTIMIO ATHINON;FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.;ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE;ALTERRA B.V.;CONSIGLIO NAZIONALE DELLE RICERCHE;UNIVERSITY OF PIRAEUS RESEARCH CENTER;UNIVERSITA DEGLI STUDI DI MILANO;WAGENINGEN UNIVERSITY;STICHTING WAGENINGEN RESEARCH";"BE;IT;CH;EL;DE;NL";"/SCI;/ITT";1;0;0;1;0;0 92306;248804;ComplexEnergy;CLO;FP7-ICT;ICT-2009.8.10;FP7;Complex Systems for an ICT-enabled Energy System;2009-11-01;2011-02-28;;"The European Energy Policy aims at achieving three core objectives: sustainability, competitiveness and security of supply. The achievement of these objectives requires a profound transformation of the energy system that will imply a huge and coordinated effort across several areas. This effort must rely on a sound analysis of different policy approaches, regulatory measures and technological choices. ICT must play a key role as one of the enablers of the energy system transformation, but also as an enabler of new advances in the modeling, analysis and governance of the system.The energy system is a clear example of a large-scale sociotechnical system composed by a myriad of heterogeneous elements working at different scales. The complex behaviour that emerges from these interactions drives classical modeling methods to their limits. Complex Systems Science is emerging as a discipline capable of offering new methods for a realistic, robust and flexible modeling of such kind of systems. New tools such as Agent-Based Simulation or Complex Networks have led to valuable results in several fields, but their application to the energy system still faces a number of open issues that require further research.ComplexEnergy is a support action whose purpose is to bridge the ICT, Energy and Complex Systems research communities in order to:- build the foundations for a new, EC-scale, interdisciplinary research community able to formulate innovative approaches to energy system modeling, design and governance;- carry out a well-defined and systematic consultation of these three research communities, as well as of policy makers and other relevant stakeholders, with the aim to identify the main strategic areas, the emerging research avenues and the major research challenges at the junction of ICT, Energy and Complex Systems; and- define a roadmap for the development of these research trends, including recommendations on research topics for FP7 calls in 2011 and beyond.";193200;170500;FP7-ICT-2009-4;/CSA;FUNDACION INSTITUTO DE INVESTIGACION INNAXIS;ES;CREATE-NET (CENTER FOR RESEARCH AND TELECOMMUNICATION EXPERIMENTATION FOR NETWORKED COMMUNITIES);IT;"/EVA;/INF;/COO;/ITT";1;0;0;1;0;0 89252;231722;IM-CLeVeR;CLO;FP7-ICT;ICT-2007.2.2;FP7;Intrinsically Motivated Cumulative Learning Versatile Robots;2009-01-01;2013-04-30;;"IM-CLeVeR aims to develop a new methodology for designing robots controllers that can: (1) cumulatively learn new efficient skills through autonomous development based on intrinsic motivations, and (2) reuse such skills for accomplishing multiple, complex, and externally-assigned tasks. During skill-acquisition, the robots will behave like children at play which acquire skills autonomously on the basis of 'intrinsic motivations'. During skill-exploitation, the robots will exhibit fast learning capabilities and a high versatility in solving tasks defined by external users due to their capacity of flexibly re-using, composing and re-adapting previously acquired skills.This overall goal will be pursued investigating three fundamental scientific and technological issues: (1) the mechanisms of abstraction of sensory information; (2) the mechanisms underlying intrinsic motivations, e.g. 'curiosity drives' that learn to focus attention and learning capabilities on 'zones of proximal development'; (3) hierarchical recursive architectures which permit cumulative learning. The study of these issues will also be fuelled by a reverse-engineering effort aiming at reproducing with bio-mimetic models the results of empirical experiments run with monkeys, children, and human adults. The controllers proposed will be validated with challenging demonstrators based on a single humanoid robotic platform (iCub).As a main outcome, the project will significantly advance the scientific and technological state of the art, both in terms of theory and implementations, in autonomous learning systems and robots. This overall goal will be achieved on the basis of the integrated work of a highly interdisciplinary Consortium involving leading international neuroscientists, psychologists, roboticists and machine-learning researchers.";7726783;5899884;FP7-ICT-2007-3;/CP;CONSIGLIO NAZIONALE DELLE RICERCHE;IT;"STIFTUNG FRANKFURT INSTITUTE FOR ADVANCED STUDIES;THE UNIVERSITY OF SHEFFIELD;UNIVERSITA CAMPUS BIO MEDICO DI ROMA;ABERYSTWYTH UNIVERSITY;SCUOLA UNIVERSITARIA PROFESSIONALE DELLA SVIZZERA ITALIANA;UNIVERSITY OF ULSTER";"DE;UK;IT;CH";"/ELM;/IPS;/TEL";1;0;0;1;0;0 89036;231608;OCTOPUS;CLO;FP7-ICT;ICT-2007.8.5;FP7;Novel Design Principles and Technologies for a New Generation of High Dexterity Soft-bodied Robots Inspired by the Morphology and Behaviour of the Octopus;2009-02-01;2013-07-31;;"The octopus is a marine invertebrate with amazing motor capabilities and intelligent behaviour. Its body has no rigid structures and has interesting characteristics, from an engineering viewpoint: infinite number of degrees of freedom (dof), bending in many different directions, variable and controllable stiffness, high dexterity, fine manipulation, highly distributed control. The octopus represents a biological demonstration of how effective behaviour in the real world is tightly related to the morphology of the body.The grand challenge of the OCTOPUS IP is investigating and understanding the principles that give rise to the octopus sensory-motor capabilities and at incorporating them in new design approaches and ICT and robotics technologies to build an embodied artefact, based broadly on the anatomy of the 8-arm body of an octopus, and with similar performance in water, in terms of dexterity, speed, control, flexibility, and applicability.The new technologies expected to result from the IP concern actuation (soft actuators), sensing (distributed flexible tactile sensors), control and robot architectures (distributed control, coordination of many dof), materials (variable stiffness), mechanisms (soft-bodied hydrostat structures), kinematics models.The final robotic octopus prototype will be capable of locomotion on different substrates, of squeezing into small apertures, of dextrous manipulation by coordinating the eight arms, of anchoring in order to exert forces on external environment; of controlling a flexible structure with virtually infinite dof.This IP is expected to achieve new science and new technology, demonstrated by joint publications and patents, through a truly interdisciplinary research work programme, by a consortium of engineering and biology groups, each involving diverse disciplines and all experienced in biomimetics, possessing, as a consortium, the best expertise available in Europe for pursuing the objectives of the IP.";9762763;7600000;FP7-ICT-2007-3;/CP;SCUOLA SUPERIORE DI STUDI UNIVERSITARI E DI PERFEZIONAMENTO SANT'ANNA;IT;"THE UNIVERSITY OF READING;WEIZMANN INSTITUTE OF SCIENCE;FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS;UNIVERSITAT ZURICH;FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA;BRUNEL UNIVERSITY LONDON;THE HEBREW UNIVERSITY OF JERUSALEM";"UK;IL;EL;CH;IT";"/ELM;/IPS;/TEL;/IND";1;0;0;1;0;0 86625;223920;VPH NoE;CLO;FP7-ICT;ICT-2007.5.3;FP7;Virtual Physiological Human Network of Excellence;2008-06-01;2013-05-31;;"The Virtual Physiological Human Network of Excellence (VPH NoE) proposal has been designed with 'service to the community' of VPH researchers as its primary purpose. Its aims range from the development of a VPH ToolKit and associated infrastructural resources, through integration of models and data across the various relevant levels of physiological structure and functional organisation, to VPH community building and support. The VPH NoE aims to foster the development of new and sustainable educational, training and career structures for those involved in VPH related science, technology and medicine, and will lay the foundations for a future Virtual Physiological Human Institute.
The VPH NoE constitutes a leading group of universities, institutes and organisations who will, by integrating their experience and ongoing activities in VPH research, promote the creation of an environment that actively supports and nurtures interdisciplinary research, education, training and strategic development. The VPH NoE will lead the coordination of diverse activities within the VPH initiative to deliver: new environments for predictive, patient-specific, evidence-based, more effective and safer healthcare; improved semantic interoperability of biomedical information and contribution to a common health information infrastructure; facile, on-demand access to distributed European computational infrastructure to support clinical decision making; and increased European multidisciplinary research excellence in biomedical informatics and molecular medicine by fostering closer cooperation between ICT, medical device, medical imaging, pharmaceutical and biotech companies.
The VPH NoE will connect the diverse VPH projects, including not only those funded as part of the VPH initiative but also those of previous EC frameworks and national funding schemes, together with industry, healthcare providers, and international organisations, thereby ensuring that these impacts will be realised.";9595662;7999367;FP7-ICT-2007-2;/NoE;UNIVERSITY COLLEGE LONDON;UK;"CONSORCIO MAR PARC DE SALUT DE BARCELONA;UNIVERSIDAD POMPEU FABRA;INSTITUT NATIONAL DE RECHERCHE ENINFORMATIQUE ET AUTOMATIQUE;INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE;UNIVERSITE LYON 1 CLAUDE BERNARD;THE UNIVERSITY OF SHEFFIELD;EUROPEAN MOLECULAR BIOLOGY LABORATORY;INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE LYON;ISTITUTO ORTOPEDICO RIZZOLI;FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS;UNIVERSITE LIBRE DE BRUXELLES;INSTITUT MUNICIPAL D'ASSISTENCIA SANITARIA;CONSIGLIO NAZIONALE DELLE RICERCHE;THE UNIVERSITY OF AUCKLAND;UNIVERSITE JOSEPH FOURIER GRENOBLE 1;THE UNIVERSITY OF NOTTINGHAM;KAROLINSKA INSTITUTET;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;GEIE ERCIM;UNIVERSITE D'EVRY-VAL D'ESSONNE;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;Sheffield Teaching Hospitals NHS Trust";"ES;FR;UK;DE;IT;EL;BE;NZ;SE";"/ELM;/IPS;/MED;/TEL";1;0;0;1;0;0 85556;216676;ECRYPT II;CLO;FP7-ICT;ICT-2007.1.4;FP7;European Network of Excellence in Cryptology - Phase II;2008-08-01;2013-01-31;;ECRYPT II is a NoE in the area of cryptology with a duration of 54 months. Cryptology is the science that studies mathematical techniques in order to provide secrecy, authenticity and related properties for digital information including the secure implementations of these techniques. It is an interdisciplinary research area with a high strategic impact for European industry and for the society as a whole. It is a fundamental enabler for secure, dependable and trusted infrastructures. The ECRYPT II research roadmap is motivated by the changing environment and threat models in which cryptology is deployed, by the gradual erosion of the computational difficulty of the mathematical problems on which cryptology is based, and by the requirements of new applications and cryptographic implementations. Its main objective is to ensure a durable integration of European research in both academia and industry and to maintain and strengthen the European excellence in these areas. In order to reach this goal, 11 leading players propose to integrate their research capabilities within three virtual labs focusing on symmetric key algorithms, public key algorithms and protocols, and hardware and software implementation. They will be joined by more than 20 adjoint members to the network who will closely collaborate with the core partners. ECRYPT II plans to build on an expand the integration activities developed within ECRYPT that include joint workshops, exchange of researchers and students, development of common tools and benchmarks and a website and forum which will be a focal point for the network and the wider cryptographic community. Spreading activities will include a training program, a substantial contribution towards standardization, bodies and an active publication policy. The project team has the critical mass and breadth to address the key questions in these areas.;4081216;3000000;FP7-ICT-2007-1;/NoE;KATHOLIEKE UNIVERSITEIT LEUVEN;BE;"INSTITUT NATIONAL DE RECHERCHE ENINFORMATIQUE ET AUTOMATIQUE;UNIVERSITA DEGLI STUDI DI SALERNO;TECHNISCHE UNIVERSITAET GRAZ;ORANGE SA;IBM RESEARCH GMBH;ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE;ECOLE NORMALE SUPERIEURE;RUHR-UNIVERSITAET BOCHUM;UNIVERSITY OF BRISTOL ROYAL CHARTER;TECHNISCHE UNIVERSITEIT EINDHOVEN;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;ROYAL HOLLOWAY AND BEDFORD NEW COLLEGE";"FR;IT;AT;CH;DE;UK;NL";"/ELM;/IPS;/TEL";1;0;0;1;0;0 85465;216710;VALUE-IT;CLO;FP7-ICT;ICT-2007.4.2;FP7;Adding Value to RTD: Accelerating Take-up of Semantic Technologies for the Enterprise;2008-03-01;2010-04-30;;"VALUE-IT will address the challenge to promote market driven alignment of EU RTD and Innovation efforts towards fostering Take-up of Semantic Technologies (ST) in business environments.

VALUE-IT will address this challenge and contribute to a faster and widespread adoption of ST within mainstream enterprise marketplace by: a) Providing a clear definition of benefits and opportunities of ST; i.e.: producing thorough technology markets assessments; identifying and understanding drivers and inhibitors for the uptake and deployment of new solutions; outlining new business and revenue models and highlighting opportunities for co-operation and new challenges for demand driven future RTD projects; b) Facilitating community building in the ST applied research arena, promoting interdisciplinary exchange of knowledge as well as shared visions for future coordination and alliances to develop, e.g. common approaches, standards and architectures and c) Fostering industry / ICT suppliers / applied researchers dialogue to promote awareness on ST, investigate potential exploitation channels and finally contribute to pave the way for market transformation.

To achieve project objectives, the VALUE-IT consortium will implement a Support Mechanism structured by four closely interlinked sets of activities: a) Business demand driven roadmapping; b) ST Innovation roadmapping; c) Roadmapping Integration and Outreach (matchmaking) activities and d) Awareness raising support activities.

Successful completion of the project will be measurable through more European companies offering semantic solutions, and more organizations progressively adopting those technologies. In particular, it will significantly help to move ST from Pioneers and Early Adopters to Mainstream Market.";1928316;1928316;FP7-ICT-2007-1;/CSA;INMARK ESTUDIOS Y ESTRATEGIAS SA;ES;"INTELLIGENT SOFTWARE COMPONENTS S.A.;DEUTSCHES FORSCHUNGSZENTRUM FUR KUNSTLICHE INTELLIGENZ GMBH;TELEFONICA INVESTIGACION Y DESARROLLO SA;OVUM EUROPE LIMITED";"ES;DE;UK";"/IPS;/INF;/TEL";1;0;0;1;0;0 85428;215918;80Days;CLO;FP7-ICT;ICT-2007.4.1;FP7;Around an inspiring virtual learning world in eighty days;2008-04-01;2010-09-30;;Recreational computer games are overwhelmingly popular. Hence, there is no doubt that educational games, which combine effective learning with fun and pleasure, are a desirable vision. Still, educational games, which can compete with their non-educational counterparts in terms of narrative and gaming quality, have not yet entered the market – especially those for children who are used to the quality of computer games. The main reason is the difficulty in merging both game and educational environments. To cross today's horizon of educational games, a scientifically sound and valid methodological and technological foundation is required. Grounding on this mission, 80Days is a RTD project concerned with theories, methodologies, and technologies for game-based learning. To accomplish a significant step towards successful and effective educational games, 80Days is addressing the following two main objectives: First, integrating models of adaptive personalised learning with those of adaptive interactive storytelling, and second, merging virtual game environments with existing learning resources, thus reducing development costs and time. These fusions will result in an adaptive and responsive system, enabling the understanding of active learning processes within a virtual learning environment, adapting to individual needs and abilities, and therefore fully exploiting the learners' capabilities. The quality of this approach will be assured by evaluation activities based on theoretically and empirically sound methods. 80Days entails the smooth integration of interdisciplinary work (learning science, storytelling, game and didactic design, game development, and human-computer interaction). 80Days delivers an innovative and advanced methodological and technological framework for effectively developing successful educational games to be demonstrated by a geography game prototype realising gaming/learning scenarios inspired by Jules Verne's 'Around the world in eighty days'.;4207281;3263839;FP7-ICT-2007-1;/CP;UNIVERSITAET GRAZ;AT;"ZENTRUM FUER GRAPHISCHE DATENVERARBEITUNG E.V.;TAKOMAT GmbH;THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN;TESTALUNA SRL;TAKOMAT JOHNE, SCHNATMANN, SCHWARZ GBR;EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH;TECHNISCHE UNIVERSITAT DARMSTADT;UNIVERSITY OF LEICESTER";"DE;IE;IT;CH;UK";"/ICT;/IPS;/INF;/TEL;/EDU";1;0;0;1;0;0 85416;215535;LarKC;CLO;FP7-ICT;ICT-2007.4.2;FP7;Large Scale Semantic Computing\nSemantic Web technologies\ndistributed reasoning\nprobabilistic reasoning\nweb-scale inference\ninformation retrieval;2008-04-01;2011-09-30;;Current Semantic Web reasoning systems do not scale to the requirements of their hottestapplications, such as analyzing data from millions of mobile devices, dealing with terabytes ofscientific data, and content management in enterprises with thousands of knowledge workers.We will build the Large Knowledge Collider (LarKC, for short, pronounced 'lark'), a platformfor massive distributed incomplete reasoning that will remove these scalability barriers. Thiswill be achieved by:- Enriching the current logic-based Semantic Web reasoning methods with methodsfrom information retrieval, machine learning, information theory, databases andprobabilistic reasoning,- Employing cognitively inspired approaches and techniques such as spreading activation,focus of attention, reinforcement, habituation, relevance reasoning, and boundedrationality.- Building a distributed reasoning platform and realising it both on a high-performancecomputing cluster and via 'computing at home'.The consortium is an interdisciplinary team of engineers and researchers in Computing Science,Web Science and Cognitive Science, well qualified to realize this ambitious vision. The LargeKnowledge Collider will be an open architecture. Researchers and practitioners from outside theconsortium will be encouraged to develop and plug in their own components to drive parts of thesystem. This will make the Large Knowledge Collider a generic platform, and not just a singlereasoning engine.The success of the Large Knowledge Collider will be demonstrated in three end-user casestudies. The first case study is from the telecom sector. It aims at real-time aggregation andanalysis of location data obtained from mobile phones carried by the population of a city, in orderto regulate city infrastructure functions such as public transport and to provide context-sensitivenavigation information. The other two case studies are in the life-sciences domain, relatedrespectively to dr;10680634;7703293;FP7-ICT-2007-1;/CP;UNIVERSITAET INNSBRUCK;AT;"ONTOTEXT AD;Information Retrieval Facility Society;THE UNIVERSITY OF SHEFFIELD;CYCORP, RAZISKOVANJE IN EKSPERIMENTALNI RAZVOJ D.O.O.;BEIJING UNIVERSITY OF TECHNOLOGY;CEFRIEL SOCIETA CONSORTILE A RESPONSABILITA LIMITATA;ASTRAZENECA AB;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;SOFTGRESS S.R.L.;UNIVERSITATEA TEHNICA CLUJ-NAPOCA;VERENIGING VOOR CHRISTELIJK HOGER ONDERWIJS WETENSCHAPPELIJK ONDERZOEK EN PATIENTENZORG;Cycorp Inc.;POLITECNICO DI MILANO;UNIVERSITAET STUTTGART;SEMANTIC TECHNOLOGY INSTITUTE INTERNATIONAL;CENTRE INTERNATIONAL DE RECHERCHE SUR LE CANCER;SIRMA SOLUTIONS JSC;SALTLUX INCORPORATED;SIEMENS AKTIENGESELLSCHAFT";"BG;AT;UK;SI;CN;IT;SE;DE;RO;NL;US;FR;KR";"/IPS;/INF;/TEL";1;0;0;1;0;0 85370;217141;SOCIALNETS;CLO;FP7-ICT;ICT-2007.8.2;FP7;Social Networking for Pervasive Adaptation;2008-02-01;2011-04-30;;The emerging information society is widely expected to experience massive embedding of both fixed and portable devices into our local physical spaces, with more and more devices having the capacity to initiate, store and communicate information and content in all aspects of life. This results in significant challenges for communication and information provision, based on required scalability, heterogeneity, re-configurability and dynamicity. The 'Social Networking for Pervasive Adaptation' project (SOCIALNETS) proposes a radical re-think for this ICT challenge by significantly departing from the traditional engineering notion of communication network. Instead, SOCIALNETS seeks to embed in devices the key characteristics that enable humans to adapt and exhibit agility beyond any other species. A human-centric approach to communication is developed by establishing social network of relations between fixed and mobile devices, as defined by the human user and their particular actions and behaviour with respect to each other and technology in the environment. Social networks are intimately connected with the human and are the basis for the SOCIALNETS paradigm. The project seeks to understand, model and exploit these structures using an interdisciplinary approach involving social anthropology, complex systems, network engineering and computer science. Relations between devices can be inherently flexible, based on casual interactions, using social models of trust and security, and without the need for 'always-on' connectivity. Furthermore, such relations build into social networks with desirable and inclusive properties that can be exploited for communication and knowledge acquisition for large numbers of devices.;2821230;2149999;FP7-ICT-2007-1;/CP;CARDIFF UNIVERSITY;UK;"THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;ETHNIKO KAI KAPODISTRIAKO PANEPISTIMIO ATHINON;UNIVERSIDADE DE AVEIRO;CONSIGLIO NAZIONALE DELLE RICERCHE;EURECOM;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD";"UK;EL;PT;IT;FR";"/ELM;/IPS;/TEL";1;0;0;1;0;0 85353;216715;NEWCOM++;CLO;FP7-ICT;ICT-2007.1.1;FP7;NEtwork of Excellence in Wireless COMmunications++ (NEWCOM++);2008-01-01;2011-04-30;;NEWCOM\\ is the acronym of a proposed Network of Excellence in Wireless COMmunications, submitted to Call 1 of the VII Framework Programme under the Objective ICT-2007.1.1: The Network of the Future, mainly in its target direction 'Ubiquitous network infrastructure and architectures'. The current proposal draws inspiration, shape/form, and substantive direction from its successful predecessor, the NoE NEWCOM, which was approved and funded by the EC for 36 months starting March 1st, 2004 and ending February 28, 2007. At the same time, NEWCOM\\ aspires to inject new vision, expanded roles, ever-higher degrees of research integration, and a definitive roadmap to financial security for the long-term life of this undertaking in the European research and higher-learning space. The core concept of NEWCOM\\ is that of an NoE of medium size, greatly reduced from the initial NEWCOM Consortium, formed by keeping the most committed and performing partners, exploiting the successful integration tools that NEWCOM designed and activated, and which is created for the purpose of scientifically addressing medium/long term, complex, interdisciplinary, fundamental research problems in the field of wireless networks, focused towards identifying, posing in the right modelling perspective, and at least partially characterizing the information-communication theoretical limits. Its main objectives are: Identify a selective set of scenarios, Define suitable performance measures that take into account the wireless channel nature, Perform a detailed analysis of the main theoretical results available, Evaluate information-theoretical bounds on the achievable performance, Design and analyze transmitting/receiving algorithms and protocols in order to approach those limits, Analyze implementation aspects of the above algorithms in flexible, energy-aware user terminals, Output the major findings into an integrated simulation library, Enhance the already good cooperation level among research;9170059;4964199;FP7-ICT-2007-1;/NoE;ISTITUTO SUPERIORE MARIO BOELLA SULLE TECNOLOGIE DELL'INFORMAZIONE E DELLE TELECOMUNICAZIONI ASSOCIAZIONE;IT;"INSTITUT NATIONAL DE RECHERCHE ENINFORMATIQUE ET AUTOMATIQUE;FTW FORSCHUNGSZENTRUM TELEKOMMUNIKATION WIEN GMBH;POLITECHNIKA POZNANSKA;UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6;TECHNISCHE UNIVERSITAET WIEN;THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;UNIVERSITEIT GENT;ETHNIKO KAI KAPODISTRIAKO PANEPISTIMIO ATHINON;CENTRE TECNOLOGIC DE TELECOMUNICACIONS DE CATALUNYA;RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN;INSTITUTE OF ACCELERATING SYSTEMS AND APPLICATIONS;INSTITUT SUPERIEUR DE L'AERONAUTIQUE ET DE L'ESPACE;TECHNISCHE UNIVERSITAET MUENCHEN;COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES;UNIVERSITE DE MARNE LA VALLEE;UNIVERSITE PARIS-SUD;UNIVERSITE CATHOLIQUE DE LOUVAIN;UNIVERSITE PARIS NANTERRE;ECOLE NATIONALE SUPERIEURE DE L'ELECTRONIQUE ET DE SES APPLICATIONS;INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE RENNES;Ecole Superieure D'Eiectricite;INSTITUT MINES-TELECOM;UNIVERSITAT POLITECNICA DE CATALUNYA;BILKENT UNIVERSITESI VAKIF;EURECOM;ECOLE NORMALE SUPERIEURE DE CACHAN;TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY;INSTITUT NATIONAL POLYTECHNIQUE DE TOULOUSE;CONSORZIO NAZIONALE INTERUNIVERSITARIO PER LE TELECOMUNICAZIONI;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;AALBORG UNIVERSITET;UNIVERSITE DE RENNES I;INSTITUTO SUPERIOR TECNICO;KARLSTADS UNIVERSITET;CHALMERS TEKNISKA HOEGSKOLA AB";"FR;AT;PL;UK;BE;EL;ES;DE;TR;IL;IT;DK;PT;SE";"/ELM;/IPS;/TEL";1;0;0;1;0;0 85271;213311;Omega;CLO;FP7-ICT;ICT-2007.1.1;FP7;Home Gigabit Access;2008-01-01;2011-03-31;;Gigabit Home Access Networks are a pivotal technology to be developed if the EU Vision of the Future Internet is to be realised. Consumers will require such HANs to be simple to install, without any new wires, and easy enough to use so that information services running on the HAN will be just another utility, as, for instance, electricity, water and gas are today. The OMEGA HAN is centred round the needs of the user: gigabit RF and optical links, combined with more robust wide-area RF and visible-light communications will provide wireless connectivity within and the home and its surroundings. Combined with power-line communications this provides a home backbone without new wires. A technology-independent MAC layer will control this network and provide services as well as connectivity to any number of devices the user wishes to connect to it in any room in a house/apartment, and further, this MAC layer will allow the service to follow the user from device to device. In order to make this vision come true, substantial progress is required in the fields of optical-wireless and RF physical layers, in protocol design, and in systems architectures. For OMEGA, an interdisciplinary team from leading institutes and companies in this broad range of technologies has been assembled. OMEGA will provide a substantial consumer pull for next-generation broadband by enabling the sharing of large-date user-generated content, which will, in turn, raise the expectation for higher data rates. Also, at the same time, a push from service providers will take place, as they see the possibility of delivering new high-bandwidth services to the user throughout the home. OMEGA will present significant market opportunities for all the EU actors in the communications industry, but most importantly empower citizens by offering access to novel emotional experiences while addressing ageing, isolation, and health challenges, and thus making an important contribution to the vision of FP7.;19057275;12413427;FP7-ICT-2007-1;/CP;ORANGE SA;FR;"SPIDCOM TECHNOLOGIES;INFINEON TECHNOLOGIES AUSTRIA AG;IHP GMBH - INNOVATIONS FOR HIGH PERFORMANCE MICROELECTRONICS/LEIBNIZ-INSTITUT FUER INNOVATIVE MIKROELEKTRONIK;ETHNIKO KAI KAPODISTRIAKO PANEPISTIMIO ATHINON;RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN;UNIVERSITA DEGLI STUDI DI UDINE;FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.;INFINEON TECHNOLOGIES AG;APSIDE S.A;Thyia Tehnologije d.o.o;CONSORZIO PER LA RICERCA NELL' AUTOMATICA E NELLE TELECOMUNICAZIONI C.R.A.T.;INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE RENNES;TECHNISCHE UNIVERSITAT DORTMUND;TELEFONICA INVESTIGACION Y DESARROLLO SA;EURESCOM-EUROPEAN INSTITUTE FOR RESEARCH AND STRATEGIC STUDIES IN TELECOMMUNICATIONS GMBH;TECHNISCHE UNIVERSITAET ILMENAU;TECHNIKON FORSCHUNGS- UND PLANUNGSGESELLSCHAFT MBH;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;Lantiq A GmbH;LANTIQ Deutschland GmbH;SIEMENS AKTIENGESELLSCHAFT;TECHNICOLOR R&D FRANCE SNC;ISKRA ZASCITE D.O.O. PODJETJE ZA IZVAJANJE ZASCIT , INZENIRING IN KOOPERACIJE";"FR;AT;DE;EL;IT;SI;ES;UK";"/ELM;/IPS;/TEL";1;0;0;1;0;0 110630;618091;SAGE;ONG;FP7-ICT;ICT-2013.9.3;FP7;Speed of Adaptation in Population Genetics and Evolutionary Computation;2014-01-01;2016-12-31;;Biological evolution has produced an extraordinary diversity of organisms, even the simplest of which is highly adapted, with multiple complex structures. Evolutionary computation has found that many innovative solutions to optimisation and design problems can be achieved by artificial evolution via random variation and selection.
Despite the centrality of evolution to biology and the usefulness of evolutionary algorithms in optimisation, the dynamics of evolution are not well understood. Consequently, population genetics theory can only make quantitative predictions about short-term, simple biological evolution, and the design and parameter tuning of evolutionary algorithms is mostly done ad-hoc in a laborious and cost-intensive process.
Both fields have studied the speed of adaptation independently, and with orthogonal approaches. Our project brings together an interdisciplinary consortium of ambitious researchers from the theory of evolutionary computation and theoretical population genetics to synergise these complementary approaches and to create the foundation of a unified quantitative theory describing the speed of adaptation in both biological and artificial evolution.
The transformative impact of this unified theory will lie in enabling long-term predictions about the efficiency of evolution in settings that are highly relevant for both fields and related sciences. Our approach will reveal how this efficiency is fundamentally determined by evolutionary and environmental parameters. Tuning these parameters will allow researchers from biology and computation to increase the efficiency of evolutionary processes, revolutionising applications ranging from evolutionary algorithms to experimental evolution and synthetic biology.;2041400;1578080;FP7-ICT-2013-C;/CP;THE UNIVERSITY OF NOTTINGHAM;UK;"Institute of Science and Technology Austria;THE UNIVERSITY OF SHEFFIELD;FRIEDRICH-SCHILLER-UNIVERSITAT JENA;HASSO-PLATTNER-INSTITUT FOR DIGITAL ENGINEERING GGMBH";"AT;UK;DE";/INF;1;0;0;1;0;0 110509;618082;ACMOL;ONG;FP7-ICT;ICT-2011.9.3;FP7;Electrical spin manipulation in electroACtive MOLecules;2014-01-01;2016-12-31;;The project 'Electrical spin manipulation in electroACtive MOLecules' (ACMOL) has the ambitious goal of fabricating a switchable, room-temperature spin-polarizer employing electro-active and magnetic molecules, which are integrated into graphene-type electrodes modified with ferromagnetic materials. The combination of these molecules with ferromagnetic electrodes is a new route in spintronics. Exploiting the high stability of graphene, we aim to demonstrate for the first time good performance of the device at room temperature. The outstanding devices can be applied to a broad number of different technological and societal fields, such as high-density data storage, microelectronics, (bio)sensors, quantum computing and medical technologies. An external electric field will be applied to read and manipulate the state of the device, as well as its charge transport properties. The characterization of the electrical response will be carried out in a 3-terminal configuration composed of source, drain and gate. The charge transport properties of the molecular junctions will be investigated in a solid-state back-gate configuration, as well as in solution, employing an 'electrolyte gate'. In this way, the devices will operate as switches that can be exploited to read and write information, which is stored in the oxidation and magnetic state of each molecule. The project involves the synthesis of the functional moieties, the device fabrication and characterization, as well as DFT modelling, which will be based on a fully quantitative description of the electronic structure at non-equilibrium. To accomplish the objectives of the project, we have chosen an interdisciplinary approach with four young research teams representing expertise in synthetic chemistry, molecular self-assembly, molecular-scale surface electrochemistry, device engineering, and DFT-based mesoscopic spin-transport calculations.;1619083;1187431;FP7-ICT-2013-C;/CP;AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS;ES;"NPL MANAGEMENT LIMITED;THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN;UNIVERSITAET BERN;UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA;TECHNISCHE UNIVERSITEIT DELFT";"UK;IE;CH;ES;NL";/ICT;1;0;0;1;0;0 107358;304886;NANOQUESTFIT;CLO;FP7-ICT;ICT-2011.9.1;FP7;Nanoparticles in Quantum Experiments: Exploring the scientific basis of future innovative quantum technologies;2013-01-01;2015-12-31;;Quantum phenomena are an important basis for future information processing and information acquisition technologies. They will become particularly relevant for quantum-enhanced metrology and advanced sensors, which exploit the quantum superposition principle at a mesoscopic scale.
NANOQUESTFIT will prepare nanoparticles in highly non-classical quantum states and utilize them to test the linearity of quantum physics over mesoscopic distances and time scales in a mass range that has remained hitherto unexplored. This goal will be realized in an interdisciplinary effort of European experts in quantum optics, nanotechnology, chemistry, and cluster physics.
NANOQUESTFIT will realize novel quantum optical elements, such as optical depletion and phase gratings, atomically thin transmission gratings, as well as doped substrates in ultra-flat silicon. This will enable quantum coherence and interference studies with objects up to and beyond 10^5 atomic mass units for the first time.
For that purpose new beam methods will be explored for tailor-made nanoparticles between 10^4 and 10^7 atomic mass units. This includes the efficient volatilization and detection of chemically functionalized nanoparticles, of pure and doped nanodroplets, as well as of cold slow cluster ions.
Decoherence is the enemy of all future quantum-based technologies. The consortium will therefore investigate environmental decoherence with objects in a complexity class that is expected to become relevant in future quantum devices.
Advanced experiments in NANOQUESTFIT will allow defining new constraints on unconventional extensions of quantum theory, which will be explored and elaborated on with regard to their conceptional consistency. Since the linearity of the Schrödinger equation is the very basis for the majority of current quantum information concepts this has direct implications for QIPC.
NANOQUESTFIT works at the cutting edge of modern science to lay the scientific ground for a better understanding of practical and fundamental limits of future quantum technologies. It will also generate spin-offs for new quantum-enhanced sensing devices: in particular the beam splitter technologies developed in NANOQUESTFIT will be applicable to a wide range of matter waves composed of atoms, molecules and genuine nanoparticles.;2629612;1994883;FP7-ICT-2011-C;/CP;UNIVERSITAT WIEN;AT;"UNIVERSITA DEGLI STUDI DI TRIESTE;UNIVERSITAT BASEL;UNIVERSITAET DUISBURG-ESSEN;TEL AVIV UNIVERSITY";"IT;CH;DE;IL";/ICT;1;0;0;1;0;0 107031;601215;Si elegans;ONG;FP7-ICT;ICT-2011.9.11;FP7;Emulating the C. elegans nervous system: A blueprint for brain-inspired computational architectures;2013-04-01;2016-09-30;;Biological neural systems are powerful, robust and highly adaptive computational entities that outperform conventional computers in almost all aspects of sensory-motor integration. Despite dramatic progress in information technology, there is a big performance discrepancy between artificial systems and brains in seemingly simple orientation and navigation tasks. In fact, no system exists that can faithfully reproduce the rich behavioural repertoire of the tiny worm Caenorhabditis elegans which features one of the simplest nervous systems in nature made of 302 neurons and about 8000 connections. Si elegans aims at providing this missing link. We propose to develop a computing framework that accurately mimics C. elegans and let complex and realistic behaviour emerge through its interaction with a rich, dynamic simulation of a natural environment. We will replicate the nervous system of C. elegans on a highly parallel, modular, arbitrarily programmable, reconfigurable and scalable hardware architecture, virtually embody it for behavioural studies in a realistic virtual environment and provide the resulting computational platform through an open-access web portal to the scientific community for its peer-validation and use. Si elegans will constitute a generalizable framework from which the universal working principles of nervous system function can be induced, and new scientific knowledge on higher brain function and behaviour can be generated. More importantly, it will lay the foundation for exploring and refining new neuromimetic computational concepts and will provide a blueprint for the design of brain-like hardware architectures that are orthogonal to current von Neumann-type machines. The 3-year project brings together a highly interdisciplinary, experienced and focused research team from leading European institutions with well-balanced complementary skills and will reach out to the world-wide scientific community in a peer-contribution and validation approach.;3570605;2727000;FP7-ICT-2011-9;/CP;FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA;IT;"NATIONAL UNIVERSITY OF IRELAND GALWAY;FUNDACION CENTRO DE TECNOLOGIAS DE INTERACCION VISUAL Y COMUNICACIONES VICOMTECH;THE NOTTINGHAM TRENT UNIVERSITY;UNIVERSITY OF ULSTER";"IE;ES;UK";/INF;1;0;0;1;0;0 106962;600610;AlterEgo;ONG;FP7-ICT;ICT-2011.2.1;FP7;Enhancing Social Interaction with an AlterEgo Artificial Agent;2013-02-01;2016-07-31;http://www.euromov.eu/alterego;The objective of AlterEgo is the creation of an interactive cognitive architecture, implementable in various artificial agents, allowing a continuous interaction with patients suffering from social disorders, by virtue of changes in behavioural (robot-based) as well as morphological (avatar-based) properties of that agent. The AlterEgo architecture is rooted in complex systems, machine learning, and computer vision. The project includes research in fundamental and clinical neurosciences, interaction modeling, development of new computer-vision techniques and human-robot interfaces, as well as evaluation of the scenarios with patients before, during, and after training sessions. At the end of the project, we will produce a new robotic-based clinical method able to enhance social interaction of patients. This new method will change existing therapies, will be applied to a variety of pathologies, and will be individualized to each patient. The first challenge of this project is to create an avatar and a robot alter ego of a patient. Based on recent work in social robotics and neurosciences, we hypothesize that if patients face artificial agents morphologically and behaviourally similar to them, they will increase their social interaction. The second challenge is to transform the morphology and the behaviour of the similar artificial agent into that of a healthy and different agent. We assume that the smooth and continuous behavioural shift from similar/unhealthy to complementary/healthy social behaviour will lead to a better social rehabilitation. AlterEgo opens the door to a new generation of social artificial agents in service robotics. AlterEgo is an interdisciplinary project composed of 7 workpackages, at the interaction of Social Motor Neurosciences (UM1), Robotics (EPFL), Complex Systems Dynamics (UOB and UNEXE), Computer Vision (DFKI), and Psychiatry (CHU).;3834912;2920000;FP7-ICT-2011-9;/CP;UNIVERSITE DE MONTPELLIER;FR;"THE UNIVERSITY OF EXETER;UNIVERSITE MONTPELLIER I.;ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE;DEUTSCHES FORSCHUNGSZENTRUM FUR KUNSTLICHE INTELLIGENZ GMBH;CENTRE HOSPITALIER UNIVERSITAIRE MONTPELLIER;UNIVERSITY OF BRISTOL ROYAL CHARTER";"UK;FR;CH;DE";/INF;1;0;0;1;0;0 106844;600826;ForgetIT;CLO;FP7-ICT;ICT-2011.4.3;FP7;Concise Preservation by combining Managed Forgetting and Contextualized Remembering;2013-02-01;2016-01-31;;"While preservation of digital content is now well established in memory institutions such as national libraries and archives, it is still in its infancy in most other organizations, and even more so for personal content. ForgetIT combines three new concepts to ease the adoption of preservation in the personal and organizational context, each overcoming major obstacles:
First, Managed Forgetting models resource selection as a function of attention and significance dynamics. It is inspired by the important role of forgetting in human memory and focuses on characteristic signals of reduction in salience. For this purpose it relies on multi-faceted information assessment and offers customizable preservation options such as full preservation, removing of redundancy, resource condensation, and also complete digital forgetting.
Secondly, Synergetic Preservation crosses the chasm that exists between active information use and preservation management by making intelligent preservation processes an integral part of the content lifecycle in information management and by developing solutions for smooth bi-directional transitions.
Thirdly, Contextualized Remembering targets keeping preserved content meaningful and useful. It will be based on a process of dynamic evolution-aware contextualization, which combines context extraction and packaging with evolution detection and intelligent re-contextualization.
To achieve these goals ForgetIT brings together an interdisciplinary team of experts in preservation, information management, information extraction, multimedia analysis, personal information management, storage computing, and cloud computing, as well as in cognitive psychology, law, and economics, who together will develop the innovative methods for realizing the ForgetIT approach.
The main expected outcomes are the flexible Preserve-or-Forget Framework for intelligent preservation management and, on top of it, two application pilots: one for personal preservation focussing on multimedia coverage of personal events and one for organizational preservation targeted at smooth preservation in organizational content management.
The ForgetIT project is expected to have different forms of socio-economic impact: a) The ForgetIT technology increases organizational productivity by enabling more concise forms of organizational memory, thus reducing the risk of work duplication and easing knowledge digestion; b) In addition, the project creates new economic opportunities for actors in technology development and consultation by opening up new application domains for preservation technology such as personal preservation as a service; c) The ForgetIT technology is an important building block for managing and preserving new bottom up forms of community memory and cultural history; and d) the managed forgetting approach provides the first step towards a promising alternative to the prevailing 'keep it all' approach in our digital society.";9085190;6590000;FP7-ICT-2011-9;/CP;GOTTFRIED WILHELM LEIBNIZ UNIVERSITAET HANNOVER;DE;"LULEA TEKNISKA UNIVERSITET;ETHNIKO KENTRO EREVNAS KAI TECHNOLOGIKIS ANAPTYXIS;THE UNIVERSITY OF SHEFFIELD;DEUTSCHES FORSCHUNGSZENTRUM FUR KUNSTLICHE INTELLIGENZ GMBH;DKD INTERNET SERVICE GMBH;TURK TELEKOMUNIKASYON AS;ARGELA YAZILIM VE BILISIM TEKNOLOJILERI SANAYI VE TICARET AS;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;EURIX SRL;IBM ISRAEL - SCIENCE AND TECHNOLOGY LTD;THE UNIVERSITY OF EDINBURGH";"SE;EL;UK;DE;TR;IT;IL";/ICT;1;0;0;1;0;0 106648;323687;UrbanIxD;CLO;FP7-ICT;ICT-2011.9.1;FP7;UrbanIxD: Designing Human Interactions in the Networked City;2013-01-01;2014-12-31;;"The UrbanIxD Coordination Action project will define and consolidate a coherent research community working in the domain of technologically augmented, data-rich urban environments; with particular focus on the human activities, experiences and behaviours that occur within them. The Coordination Action will employ a 'Critical Design' methodology to explore social and technological issues that will be important to future FET research agendas. This Critical Design methodology will act as a catalyst for reflection and examination, leading to a high-profile public outreach programme, including an exhibition, and will enable the production of an informed Research Agenda output. This Agenda document will use the exploratory design activities carried out across the duration of the project to reflect upon emergent issues, and synthesise these into a focussed statement on future research directions.
Interaction Design, in an urban context, is an increasingly important field of research. City populations are currently in a state of rapid flux. Conurbations are fast becoming a hybrid of the physical environment and the digital datasphere. How we, as physical beings, will connect with, interpret and adapt this increasing dataflow residing in our cities is already becoming a significant research question. The UrbanIxD Coordination Action will take a human-centred view of the concerns, experiences and behaviours that may occur in cities of the future. In order for advances in ICT to make the progression into real, transformative benefits for Europe's citizens, industry and society, there is a need to investigate the real, embodied and situated nature of interaction with these networked, and essentially heterogeneous, city environments. This is a challenge that can only be addressed through increasing interdisciplinary understanding and collaboration.";538457;453150;FP7-ICT-2011-C;/CSA;EDINBURGH NAPIER UNIVERSITY;UK;"AARHUS UNIVERSITET;SVEUCILISTE U SPLITU;TELECOM ITALIA SPA";"DK;HR;IT";/ICT;1;0;0;1;0;0 105872;318051;iTalk2Learn;CLO;FP7-ICT;ICT-2011.8.1;FP7;Talk, Tutor, Explore, Learn: Intelligent Tutoring and Exploration for Robust Learning;2012-11-01;2015-10-31;;In the aftermath of the PISA studies, which identified weaknesses of students in many European countries, especially in mathematics, the education of children in the elementary school grades has received a lot of attention. Yet, most learning systems that have been developed for mathematics education have two significant limitations: first, they are usually constrained to text-based interactions and are thus hard to use by young learners (6 to 11-year-olds) who are still perfecting their basic literacy skills. Second, support is rarely tailored to the children's needs in an adaptive fashion, even though depending on the current stage of the learning process, the support that children need varies between structured practice and more exploratory, conceptually-oriented learning.
The Intelligent Tutoring and Exploration for Robust Learning project aims to facilitate robust learning by creating a platform for intelligent support that combines structured learning with exploratory learning activities and applies cognitive models of the learning behaviour of students in elementary education. Relying on state-of-the-art machine learning methods, intelligent components will be able to provide adaptive feedback -- e.g., praise or hints --and suggest subsequent tasks. The platform will enable learners to communicate and interact more naturally via rich intuitive user interfaces leveraging direct manipulation and, in particular, natural language user interfaces. The pedagogical and technological outcomes of the project will be evaluated in two proven application scenarios in two European languages.
The project proposes to perform interdisciplinary, cutting-edge research in a multidisciplinary team with members from fields as diverse as artificial intelligence/machine learning, user modelling, intelligent tutoring systems, and natural language processing, as well as educational psychology and mathematics education.;3060744;2400000;FP7-ICT-2011-8;/CP;STIFTUNG UNIVERSITAT HILDESHEIM;DE;"SAIL LABS TECHNOLOGY GMBH;TESTALUNA SRL;INSTITUTE OF EDUCATION, UNIVERSITY OF LONDON;BIRKBECK COLLEGE - UNIVERSITY OF LONDON;RUHR-UNIVERSITAET BOCHUM;WHIZZ EDUCATION LIMITED;UNIVERSITY COLLEGE LONDON";"AT;IT;UK;DE";"/ICT;/EDU";1;0;0;1;0;0 105162;317681;Social-IST;CLO;FP7-ICT;ICT-2011.9.12;FP7;Social Collective Intelligence;2012-10-01;2013-10-31;;The Social-IST Support Action aims at catalysing interdisciplinary collaborations and at organising consultations of multidisciplinary research communities on the theme of Social Collective Intelligence. The term is used to denote a class of socio-technical systems that combine, in a coordinated way, the strenghts of humans and groups in terms of competences, knowledge and problem solving capabilities with the communication, computing and storage capabilities of advanced information and communication technologies. Social Collective Intelligence systems have the potential to radically change the way we approach and tackle global societal challenges.The Social-IST project will deliver a White Paper on research challenges in Social Collective Intelligence and a Roadmap document for possible future FET initiatives in the field. The proposed Support Action will leverage on a multidisciplinary Scientific Panel with leading scientists in the respective fields, that will be brought together in two highly interactive workshops. Online consultations will be run to gather inputs from the scientific community at large.The results of the Support Action will be presented in a final public event, that will target high-profile representatives from academia and industry, together with European Commission delegates.;276576;231993;FP7-ICT-2011-8;/CSA;CREATE-NET (CENTER FOR RESEARCH AND TELECOMMUNICATION EXPERIMENTATION FOR NETWORKED COMMUNITIES);IT;"SIGMA ORIONIS SA;THE UNIVERSITY OF EDINBURGH";"FR;UK";/LIF;1;0;0;1;0;0 104931;318804;SNM;ONG;FP7-ICT;ICT-2011.3.1;FP7;Single Nanometer Manufacturing for beyond CMOS devices;2013-01-01;2017-03-31;;"To extend beyond existing limits in nanodevice fabrication, new and unconventional lithographic technologies are necessary to reach Single Nanometer Manufacturing (SNM) for novel 'Beyond CMOS devices'. Two approaches are considered: scanning probe lithography (SPL) and focused electron beam induced processing (FEBIP). Our project tackles this challenge by employing SPL and FEBIP with novel small molecule resist materials. The goal is to work from slow direct-write methods to high speed step-and-repeat manufacturing by Nano Imprint Lithography (NIL), developing methods for precise generation, placement, metrology and integration of functional features at 3 - 5 nm by direct write and sub-10nm into a NIL-template. The project will first produce a SPL-tool prototype and will then develop and demonstrate an integrated process flow to establish proof-of-concept 'Beyond CMOS devices' employing developments in industrial manufacturing processes (NIL, plasma etching) and new materials (Graphene, MoS2). By the end of the project: (a) SNM technology will be used to demonstrate novel room temperature single electron and quantum effect devices; (b) a SNM technology platform will be demonstrated, showing an integrated process flow, based on SPL prototype tools, electron beam induced processing, and finally pattern transfer at industrial partner sites. An interdisciplinary team (7 Industry and 8 Research/University partners) from experienced scientists will be established to cover specific fields of expertise: chemical synthesis, scanning probe lithography, FEBIP-Litho, sub-3nm design and device fabrication, single nanometer etching, and Step-and-Repeat NIL- and novel alignment system design. The project coordinator is a University with great experience in nanostructuring and European project management where the executive board includes European industry leaders such as IBM, IMEC, EVG, and Oxford Instruments.";17556768;12012000;FP7-ICT-2011-8;/CP;TECHNISCHE UNIVERSITAET ILMENAU;DE;"MICROSYSTEMS LTD;IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE;EV GROUP E. THALLNER GMBH;INTERUNIVERSITAIR MICRO-ELECTRONICA CENTRUM;IBM RESEARCH GMBH;VSL B.V.;OXFORD SCIENTIFIC CONSULTANTS LTD;ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE;AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS;OXFORD INSTRUMENTS NANOTECHNOLOGY TOOLS LIMITED;THE UNIVERSITY OF LIVERPOOL;UNIVERSITAET BAYREUTH;SWISSLITHO AG;THE OPEN UNIVERSITY;TECHNISCHE UNIVERSITEIT DELFT";"BG;UK;AT;BE;CH;NL;ES;DE";/NNT;1;0;0;1;0;0 104365;296162;BIOPOOL;CLO;FP7-ICT;ICT-2011.4.1;FP7;SERVICES ASSOCIATED TO DIGITALISED CONTENTS OF TISSUES IN BIOBANKS ACROSS EUROPE;2012-09-01;2014-08-31;;Biobanks are facilities that provide archived human biological samples for their use in health research. They are pools of biologic material and associated health information such as pathologies and treatments, and the materials stored and their associated information are very relevant for research purposes, among others. Biobanks are increasingly digitalising their biologic material (digital images and associated textual information), but ICT power is still underused. Currently, the digital images are usually spread all over different systems stored in different formats, databases and facilities belonging to different institutions. These image collections own a very valuable knowledge in several fields, but the exploitation of this potential requires mechanisms to gather, access, visualize, process, understand and exploit large image collections. BIOPOOL objective is to build a system able to link pools of digital data managed by biobanks (comprised by histological digital images of the biologic material and the data associated to these images) and to develop added value services for the exploitation of this information (data sharing, image visualization, text and image based search queries and advanced functions such as region-of-interest extraction or automated pathology information extraction in certain cancer types). BIOPOOL aims to establish an intelligent biobank network, demonstrating the potential of this data pool for medical research, diagnosis and educational activities. BIOPOOL consortium is composed of an interdisciplinary group of experienced partners with complementary roles, including 3 innovative SMEs, being the main beneficiaries of the project results commercialization. BIOPOOL has a clear route for exploitation and will not only allow SMEs and biobanks to increase their offer of products and services but also will improve their current business, and will enhance the pathology research efficiency by reducing the diagnosis time and related cost.;2441629;1966000;FP7-ICT-2011-SME-DCL;/CP;FUNDACION VASCA DE INNOVACION E INVESTIGACION SANITARIAS;ES;"FUNDACION TECNALIA RESEARCH & INNOVATION;PERTIMM DEVELOPPEMENT;Servicio Vasco de Salud Osakidetza;FUNDACION CENTRO DE TECNOLOGIAS DE INTERACCION VISUAL Y COMUNICACIONES VICOMTECH;PERTIMM (PERTINENT ET IMMEDIAT) SAS;EMEDICA SL;CULTEK SL;BRUNEL UNIVERSITY LONDON;ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM";"ES;FR;UK;NL";"/ICT;/BUS";1;0;0;1;0;0 103889;293431;PLANTOID;CLO;FP7-ICT;ICT-2011.9.1;FP7;Innovative Robotic Artefacts Inspired by Plant Roots for Soil Monitoring;2012-05-01;2015-04-30;;"We aim at designing, prototyping, and validating a new generation of ICT hardware and software technologies inspired from plant roots, called PLANTOIDS, endowed with distributed sensing, actuation, and intelligence for tasks of environmental exploration and monitoring. PLANTOIDS take inspiration from, and aim at reproducing, the amazing penetration, exploration, and adaptation capabilities of plant roots. Plants have evolved very robust growth behaviours to respond to changes in their environment and a network of highly sensorized branching roots to efficiently explore the soil volume, mining minerals and up-taking water. PLANTOID has two major goals: 1) to abstract and synthesize with robotic artefacts the principles that enable plant roots to effectively and efficiently explore and adapt to underground environments; 2) to formulate scientifically testable hypotheses and models of some unknown aspects of plant roots, such as the role of local communication among root apices during adaptive growth and the combination of rich sensory information to produce collective decisions. The PLANTOID artefact will be composed of a network of sensorized and actuated roots, displaying rich sensing and coordination capabilities as well as energy-efficient actuation and high sustainability, typical of the Plant Kingdom. Each PLANTOID root will consist of an apex that comprises sensors, actuators, control units, and by an elongation zone that mechanically connects the apex and the trunk of the robot. The new technologies expected to result from PLANTOID concern energy-efficient actuation systems, chemical and physical micro-sensors, sensor fusion techniques, kinematics models, and distributed, adaptive control in networked structures with local information and communication capabilities. The foundational research program of PLANTOID will be carried out by a consortium of engineers, plant biologists, and computer scientists with demonstrated experience in interdisciplinary work.";2091887;1619924;FP7-ICT-2011-C;/CP;FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA;IT;"UNIVERSITA DEGLI STUDI DI FIRENZE;FUNDACIO INSTITUT DE BIOENGINYERIA DE CATALUNYA;ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE";"IT;ES;CH";/ICT;1;0;0;1;0;0 103707;295293;QuILMI;CLO;FP7-ICT;ICT-2011.9.3;FP7;Quantum Integrated Light Matter Interface;2012-10-01;2016-03-31;;This project brings together an interdisciplinary team of young, ambitious and internationally recognized researchers. The aim of the proposed research is to create a highly integrated device, which permits to manipulate, store and control light on a single-photon level using tailored quantum matter. Specifically, we will implement a three-dimensional optical lattice on an atom chip together with sophisticated waveguides for single-photon manipulation and detection, all integrated on the very same chip. Our vision is that this device becomes the centerpiece of novel hybrid light-matter networks, with which quantum information processing can be approached from a highly modularized standpoint. Our objective is to develop a far-reaching theoretical framework for light-matter interaction on an atom chip and to conduct experiments that, for the first time, demonstrate both coherent light-matter coupling and single-photon detection in an integrated device. This proof-of-principle demonstration will push quantum technology and methods beyond the current state-of-the-art. To achieve this ambitious goal we will exploit the combined expertise of our team in theoretical and experimental quantum optics, atomic physics and many-body physics. The proposed project promises high benefit for the European Research Area, as its prospective achievements will advance applications in quantum technology, and strongly enhance the competitive edge of European Research. The envisioned program will promote young researchers from different European countries and will allow them to forge a new international research alliance. This contributes to the exploitation of synergies in the European science scene, thereby building and securing leadership of Europe in ICT research.;1624571;1228876;FP7-ICT-2011-C;/CP;THE UNIVERSITY OF NOTTINGHAM;UK;"UNIVERSITAT WIEN;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;FRIEDRICH-SCHILLER-UNIVERSITAT JENA";"AT;DE";/ICT;1;0;0;1;0;0 102378;284553;SI-CODE;CLO;FP7-ICT;ICT-2011.9.1;FP7;Towards new Brain-Machine Interfaces: state-dependent information coding;2012-03-01;2015-08-31;;"Brain Machine Interfaces (BMIs) are devices mediating communication between a brain and the external world, and hold the potential for a) restoring motor or sensory functions to people who lost them due to illness or injury, and b) understanding neural information processing through controlled interactions between neurons and external devices. However, the success of BMIs is hampered by the problem that neural responses to external correlates are highly variable because they depend on the internal state of the neural network. We propose to remove this obstacle by developing a radically new generation of 'bidirectional BMIs' (which decode information from the recorded neural activity and provide information to the brain by stimulation) employing neural computational strategies and neuromorphic VLSI devices that i) understand how network states influence neural responses to stimuli; ii) use this know-how to discount variability induced by state changes in real time and thus operate with increased bandwidth and performance. We gather a highly interdisciplinary team composed of both mathematical and experimental neuroscientists and of VLSI engineers. We will study the interplay between ongoing network states and stimulus-evoked responses in various nervous systems of different complexity. We will develop advanced algorithms and models of network dynamics to determine the network state variables best predicting and discounting neural variability, and to construct optimal state-dependent rules to decode neural activity. We will implement these algorithms in a new 'state-dependent bidirectional BMI' prototype using low-power neuromorphic VLSI circuits that extract in real time network state information and use it to produce outputs optimally suited for both decoding of recorded signals and delivering electrical stimulation to a neural tissue in a given state. This BMI will be tested in a benchmark experiment in rats to guide an external device with closed loop control.";3271041;2471230;FP7-ICT-2011-C;/CP;FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA;IT;"MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;SCUOLA INTERNAZIONALE SUPERIORE DI STUDI AVANZATI DI TRIESTE;UNIVERSITAT ZURICH;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS";"DE;IT;CH;FR";/ICT;1;0;0;1;0;0 102483;284566;PROMISCE;CLO;FP7-ICT;ICT-2011.9.1;FP7;Quantum Propagating Microwaves in Strongly Coupled Environments;2012-04-01;2015-09-30;;The aim of PROMISCE is to provide the foundations for a novel research field: propagating quantum microwave technologies in strongly and ultrastrongly coupled environments. In particular, its potential for scalable quantum information and communication technology (Q-ICT) applications will be demonstrated. PROMISCE is born from a challenging and controversial idea, which is that microwave photons can interact strongly among each other and with their environment even in the absence of confining cavities.PROMISCE combines two major innovative and interdisciplinary components. The first one, propagating quantum microwave photonics, focuses on the generation, control, and detection of quantum microwave beams and photons using superconducting quantum circuits. The second component aims at exploring propagating quantum microwave interactions. Novel paths in engineering strong and ultrastrong controlled interactions between propagating microwave photons and their environment, and among photons themselves, will be pursued. To this end, we will employ superconducting quantum circuits and develop sophisticated quantum metamaterials. We note that both components are intimately connected: technological and conceptual achievements in one component will immediately trigger progress in the other one. Together they will provide, integrated on a chip, the equivalent of optical Q-ICT experiments in the microwave regime.PROMISCE represents a complete paradigm shift beyond the common interest in superconducting qubits for Q-ICT to the concept of encoding quantum information in propagating microwave photons and using an (ultra-)strongly coupled environment as the basic tool for their manipulation. In this context, PROMISCE also introduces a new understanding of the term 'environment'. Instead of being seen as a source of decoherence or noise, it is converted into a powerful tool for control, communication and information processing.;2869083;2168921;FP7-ICT-2011-C;/CP;AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS;ES;"BAYERISCHE AKADEMIE DER WISSENSCHAFTEN;UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA;CHALMERS TEKNISKA HOEGSKOLA AB";"DE;ES;SE";/ICT;1;0;0;1;0;0 102149;288587;MASELTOV;CLO;FP7-ICT;ICT-2011.5.5;FP7;Mobile Assistance for Social Inclusion and Empowerment of Immigrants with Persuasive Learning Technologies and Social Network Services;2012-01-01;2015-03-31;;MASELTOV recognises the major risks for social exclusion of immigrants from the European information society and identifies the huge potential of mobile services for promoting integration and cultural diversity in Europe. Mobile – everywhere/everytime - persuasive assistance is crucial for more efficient and sustainable support of immigrants. MASELTOV researches and develops novel ICT instruments in an interdisciplinary consortium with the key objective to facilitate and foster local community building, raising consciousness and knowledge for the bridging of cultural differences.MASELTOV realises this project goal via the development of innovative social computing services that motivate and support informal learning for the appropriation of highly relevant daily skills. A mobile assistant embeds these novel services that address activities towards the social inclusion of immigrants in a persuasive and most intuitive manner which is highlighted in MASELTOV with a representative application of most essential / beneficial information and learning services – such as ubiquitous language translation, navigation, administrative and emergency health services.MASELTOV researches for and develops enabling technologies with the industrial potential to easily exploit and scale up the prototypical user shares within the embedment of already existing successful services with worldwide user coverage. The project with its scientifically, technically and socially relevant results will enable a massive social impact on the future with respect to more cooperative – more successful - integration of millions of (im)migrants living together with hundreds of millions cohabitating European citizens.;5098326;3751000;FP7-ICT-2011-7;/CP;JOANNEUM RESEARCH FORSCHUNGSGESELLSCHAFT MBH;AT;"VEREIN DANAIDA;COVENTRY UNIVERSITY;AIT AUSTRIAN INSTITUTE OF TECHNOLOGY GMBH;FUNDACIO PER A LA UNIVERSITAT OBERTA DE CATALUNYA;RESEARCH AND EDUCATION LABORATORY IN INFORMATION TECHNOLOGIES;FUNDACION DESARROLLO SOSTENIDO;THE MIGRANTS' RESOURCE CENTRE;CURE CENTRUM FUR DIE UNTERSUCHUNG UND REALISIERUNG ENDBENUTZERORIENTIERTER INTERAKTIVER SYSTEME;CESKE VYSOKE UCENI TECHNICKE V PRAZE;FH JOANNEUM GESELLSCHAFT MBH;BUSUU ONLINE S.L;THE OPEN UNIVERSITY;TELECOM ITALIA SPA;FLUIDTIME DATA SERVICES GMBH;BUSUU LIMITED;PEARSON PUBLISHING LIMITED";"AT;UK;ES;EL;CZ;IT";/INF;1;0;0;1;0;0 102147;288382;POETICON++;CLO;FP7-ICT;ICT-2011.2.1;FP7;Robots need Language: A computational mechanism for generalisation and generation of new behaviours in robots;2012-01-01;2015-12-31;;Handling novel situations beyond learned schemas or set behaviours is still a quest in engineering cognitive and embodied systems. Simply put, sensorimotor experiences in real world are non-finite and therefore powerful generalisation mechanisms are necessary for any agent to operate effectively in real-world environments.POETICON\\ suggests that natural language can be used as a learning tool for:(a) generalisation of learned behaviours and perceptual experiences, and(b) generation of new behaviours and experiences (creativity).This is a new approach to behaviour and perception generalisation for artificial agents that capitalises on the use of a hierarchical and generative symbolic system for 'indexing' (labelling) sensorimotor experiences at different levels of abstraction. Motivated by experimental findings on a common neurological basis between language, perception and action (a common syntax), POETICON\\ suggests the use of natural language for generalisation and generation of sensorimotor 'syntactic structures'.The main objective of POETICON\\ is the development of a computational mechanism for such generalisation of motor programs and visual experiences for robots. To this end, it will integrate natural language and visual action/object recognition tools with motor skills and learning abilities, in the iCub humanoid. Tools and skills will engage in a cognitive dialogue for novel action generalisation and creativity experiments in two scenarios of 'everyday activities', comprising of (a) behaviour generation through verbal instruction, and (b) visual scene understanding.POETICON\\ views natural language as a necessary tool for endowing artificial agents with generalisation and creativity in real world environments. Building on results from the POETICON project, it brings together an extended interdisciplinary group of experts for developing the first ever computational mechanism that will use language as a behaviour/experience generalisation tool.;5123166;3880000;FP7-ICT-2011-7;/CP;FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA;IT;"COGNITIVE SYSTEMS RESEARCH INSTITUTE;THE UNIVERSITY SYSTEM OF MARYLAND FOUNDATION, INC.;ATHINA-EREVNITIKO KENTRO KAINOTOMIAS STIS TECHNOLOGIES TIS PLIROFORIAS, TON EPIKOINONION KAI TIS GNOSIS;UNIVERSITY OF PLYMOUTH;INSTITUTO SUPERIOR TECNICO";"EL;US;UK;PT";/INF;1;0;0;1;0;0 100728;283686;GLOBAL excursion;CLO;FP7-INFRASTRUCTURES;INFRA-2011-3.4.;FP7;GLOBAL excursion - Extended Curriculum for Science Infrastructure Online;2011-09-01;2014-02-28;;GLOBAL excursion will introduce e infrastructures to educators and pupils. It provides scientists, policy makers, pupils and their teachers a package of activities, materials and tools for enabling the integration of e infrastructures into school curricula. Main access point is the GLOBAL Virtual Science Hub – 'ViSH'. It contains a selection of e Infrastructures, and a social network where scientists, teachers and pupils will be able to exchange and establish collaborations, and a virtual excursion room, where pupils will be able to experience real e-science applications in areas of high relevance for the future, such as nano- and biotechnologies.The technological basis of the Virtual Science Hub is the VCC, a communication platform developed in the GLOBAL project, which has already proven to successfully link distant researchers and to integrate remote regions.To allow for closer links between stakeholder communities, the hub will include a pedagogical framework that tailors science content to the needs of schools preconditions. With this aim, teachers and scientists will be involved in a user-centred design process and collaboratively elaborate generic tools and methods, offering joyful formats attractive to young people. With the ViSH portal as a hub, virtual excursions are possible through existing e-infrastructures and together with pedagogical concepts, a more efficient use of e infrastructures will be ensured. Teachers will have access to guided and compact materials, easy to implement and adapt in their teaching activities.
Together with end-users, GLOBAL excursion will develop a common understanding, teaching use cases, as well as pedagogical and technical artefacts. The aim of this project proposal is to provide young citizens and their educators (teachers, parents, etc.) across Europe with a range of e-Infrastructures and access to expert knowledge on its usage for a joyful exploration of e-Science through e-Infrastructure. Based on the experience from previous projects, we intend to target pupils between 14-18 years of age (upper stage school). Participating schools and science communicators will elaborate communication and teaching activities. The driving themes will be nano- and biotechnologies, as well as volunteer computing and life sciences with an interdisciplinary focus especially including ethical, legal and social aspects (ELSA).
The main purpose of the GLOBAL excursion project is to enable students and teachers access to the experimental laboratories and resources of selected e-Infrastructures in order to improve science curricula by enriching school's existing teaching and learning materials. By connecting e Infrastructures, resources and tools with schools, pupils can experience challenging and authentic learning scenarios. Thus, students gain insights in scientific real work and relive interest in natural science education.;912695;800000;FP7-INFRASTRUCTURES-2011-2;/CSA;ZENTRUM FUER SOZIALE INNOVATION;AT;"THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;UNIVERSIDAD DE ZARAGOZA;EUN PARTNERSHIP AISBL;MAGYAR TUDOMANYOS AKADEMIA SZAMITASTECHNIKAI ES AUTOMATIZALASI KUTATOINTEZET;AGORA SYSTEMS, S.A.;UNIVERSIDAD POLITECNICA DE MADRID";"UK;ES;BE;HU";/COO;1;0;0;1;0;0 91756;235973;LAG;ONG;FP7-PEOPLE;FP7-PEOPLE-IEF-2008;FP7;Learning Across Games;2009-08-15;2011-08-14;;In this proposal we aim to study the twin questions of a) how agents categorize decision problems (and in particular games) according to their similarity and b) how this categorization affects standard predictions in Game Theory. The most important contribution to the literature is that we endogenize the question of categorization, assuming that categorizations can be learned. Existing literature is characterized by making sometimes ad hoc assumptions on categorizations. Initial results have already shown that some of the key concepts used in Game Theory appear to be very fragile once the problem of categorization is introduced. We have also shown that many recent experimental results have a natural explanation in terms of learned categorizations. Possibly because of these results the research has already had quite some impact, reflected for example in a large number of seminar invitations. My personal background allows me to approach this issue in an interdisciplinary manner. Many cognitive scientists have been interested in the question of categorization and there are interesting applications even to Biology, in particular to the problem of genomic imprinting. Other applications in Economics concern bidding of firms in search or procurement auctions. Data from such applications can be used to test the theory. The project is executed at the Department of Economics at Maastricht University, in cooperation with an international group of top researchers working on closely related issues.;;152430,52;FP7-PEOPLE-IEF-2008;/MC-IEF;UNIVERSITEIT MAASTRICHT;NL;;;"/SCI;/EMP";1;0;0;1;0;0 88044;221002;METAGENOGRIDS;ONG;FP7-PEOPLE;PEOPLE-2007-4-1.IOF;FP7;Algorithmics for Metagenomics on Grids;2008-07-17;2010-07-16;;"Numerous critical problems in bioinformatics and computational biology are computationally intensive and could benefit from being solved on a computational Grid, that is a network of geographically distributed computers. Most works that combine bioinformatics and Grids focus on biological problems that can be trivially adapted to Grids, staying clear of more complex problems. In this fellowship we propose to address, in an interdisciplinary research, the resolution on Grids of two complex and demanding problems: metagenomics assembly and metagenomics annotation. Metagenomics is the study of the genomes of an entire community of microbes; metagenomics assembly is the problem of assembling the genome of each of the microbial species in the studied community. The applicant, a Grid computing expert, proposes to work with experts in bioinformatics and experts in Grid computing to design new algorithmic solutions to solve these two metagenomics problems. In this proposal, the applicant would simultaneously visit for a year, and work with, Prof. Guylaine Poisson's Bioinformatics Lab (BiL) and Prof. Henri Casanova's Concurrent Research Group (CoRG), both located at the University of Hawai`i at Manoa, USA.";118572,06;118572,06;FP7-PEOPLE-2007-4-1-IOF;/MC-IOF;INSTITUT NATIONAL DE RECHERCHE ENINFORMATIQUE ET AUTOMATIQUE;FR;;;"/SCI;/COO";1;0;0;1;0;0 91143;237725;ALCH;ONG;FP7-PEOPLE;FP7-PEOPLE-IEF-2008;FP7;Early Arabic Literature in Context: the Hellenistic Continuum;2009-07-01;2011-06-30;;This proposal addresses the inter-cultural exchanges in Egypt during the 11th century, as embedded in an Arabic compilation of ancient sources on the Greek, Egyptian and Semitic sages (prophets, heroes, philosophers and famous physicians). Written by Ibn Fatik and misleadingly entitled Choicest Maxims and Best Sayings, the work was read as early as the middle of the 13th century in Spain, and thereafter translated into the main European languages. The circulation of the text on both the Eastern and Western sides of the Mediterranean during the medieval times reflects the complexity of the late antique/early medieval societies. Figures such as Hermes, Pythagoras, Hippocrates, Alexander the Great, and Galen, receive the rank of Hellenistic semi-gods. Written in an Islamic Shi’i context (the Fatimid court in Cairo), the work, based on earlier compilations and translations, and widely circulating in later Arabic literature, calls for a re-appraisal of the Greek and Hellenistic roots of both the Judaeo-Christian and Islamic civilizations. The project will focus on the historical context and the linguistic aspects of the text, as the work belongs to a well-represented genre of early Arabic literature using both Greek and Syriac translated materials. A study of the network behind the text will help to re-assess the ‘translation movement’ in Baghdad and surrounding area during the 9th-10th centuries. This literature of ‘Tales and Legends of Greece and the Ancient Near East’ can only be studied within an interdisciplinary framework. My project, at the crossroads of Arabic literature, Greek philosophy and history, and religious studies, aims to study the corpus of the Greek and Syriac literature translated into Arabic during the 8th-13th centuries from new angles. This approach will bring out the role of Egypt as a centre of intellectual exchanges between multifarious communities in the pre-Crusades period, and uncover unknown sources on the ancient Greek philophers.;;151863,51;FP7-PEOPLE-IEF-2008;/MC-IEF;UNIVERSITEIT LEIDEN;NL;;;"/SCI;/EMP";1;0;0;1;0;0 88024;220644;OGPLIE;ONG;FP7-PEOPLE;PEOPLE-2007-2-1.IEF;FP7;“Ortega y Gasset’s Philosophy of Life and His Idea of Europe”;2008-06-04;2010-06-03;;Abstract: “Ortega y Gasset’s Philosophy of Life and His Idea of Europe” The aim of the philosophical research project “Ortega y Gasset’s Philosophy of Life and His Idea of Europe” is to enable a twofold synthesis under a systematic perspective: The first stage consists in developing a philosophical notion of culture as well as a notion of cultural consciousness within an interdisciplinary bridging of Philosophy and Spanish Studies. The second stage will be marked by a shift from cultural philosophy to European Studies. Europe will be examined as a paradigmatic example of a historically growing, self-contained cultural reality with a specific mode of consciousness and awareness of life manifested in local customs. From a historical perspective the thought of José Ortega y Gasset constitutes the core of the project. José Ortega y Gasset is considered to be the most significant Spanish thinker of the twentieth century. The project aims not only to examine his work as an original conception of a philosophy of life and culture, but also to outline Ortega’s importance as a pioneer in European integration. It is my intention to combine through this project the two subjects I have studied, Philosophy and Spanish Studies, in order to improve my skills in intercultural academic dialogue. At the same time I hope to carve out a research profile in European Studies through the application of various theoretical approaches to a number of research areas, thus improving my qualifications and broadening my academic prospects throughout Europe. The internationally renowned host organisation I am working with in this research project - Instituto de Filosofia (CSIC) in Madrid – is an excellent starting point to develop this new perspective. The project “Ortega y Gasset’s Philosophy of Life and His Idea of Europe” was conceived as a contribution to the further development of a European identity and consciousness and a significant bridge between German and Spanish European research.;207884,12;207884,12;FP7-PEOPLE-2007-2-1-IEF;/MC-IEF;AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS;ES;;;"/SCI;/EDU";1;0;0;1;0;0 109292;618439;BSMEXPLORE;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-CIG;FP7;Looking for physics beyond the standard model in unexplored regions at the LHC and flavour experiments;2013-08-01;2018-10-09;;This project is about the search for physics beyond the standard model in contemporary experiments, both the ones at the Large Hadron Collider (LHC) and the ones looking for flavour violating processes. It is a highly interdisciplinary project, since it located at the borders between experimental and theoretical physics. One of the main goals of my proposal is to provide the experimentalists the tools they need in order to search for new physics in their data looking at yet unexplored signatures. As a first step I intend to simulate the expected signals in the framework of a recently proposed supersymmetric model with R-parity violation, using important simulation programs like FeynRules and MadGraph. Then a more general analysis of possible forgotten signatures will be realised, as well as a theoretical investigation following the experimental results. In parallel to this LHC-oriented program, I propose to tackle the flavour experiments in an original model-independent way, by looking at all the simplest possibilities (1 or 2 new particles, of any kind) able to give a signal in MEG. Then I will calculate the correlations with other indirect experiments and the possibility of testing the corresponding new physics in the LHC. This project is very timely, since these experiments are running now and there is the need of exploiting to the maximum their capability of looking for new physics.;100000;100000;FP7-PEOPLE-2013-CIG;/MC-CIG;UNIVERSITA DEGLI STUDI DI GENOVA;IT;;;/LIF;1;0;0;1;0;0 109144;606889;RAPID;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-ITN;FP7;Reactive Atmospheric Plasma processIng - eDucation network;2013-10-01;2017-09-30;;'The goal of the Multi-Partner ITN-RAPID (Reactive Atmospheric Plasma processIng - eDucation network) is the realization of an interdisciplinary training involving the disciplines physics, chemistry and engineering. As a result, RAPID will create the platform for a truly European PhD in plasma technology. The scientific goal is the development of non-equilibrium reactive processes in atmospheric pressure plasmas. Thereby, the great success of low pressure plasmas enabling a multitude of applications ranging from material synthesis, automotive and microelectronics can be repeated. In addition, even more applications become possible due to the easy integration of atmospheric pressure plasmas in current industrial processes. Hot topics such as large area solar cells, barrier coatings to improve the permeation properties of polymers and plasma chemical gas conversion are selected. The research success requires a specific training covering diverse aspects such as modeling and simulation of plasmas and surfaces, diagnostic to validate these models and the implications for industrial scale-up. This will be trained in a coordinated effort involving 10 academic and 10 industrial partners from 8 European countries.';3896422,09;3896422,09;FP7-PEOPLE-2013-ITN;/MC-ITN;RUHR-UNIVERSITAET BOCHUM;DE;"VLAAMSE INSTELLING VOOR TECHNOLOGISCH ONDERZOEK N.V.;UNIVERSITEIT ANTWERPEN;THE UNIVERSITY OF MANCHESTER;Fraunhofer EMFT;FUJIFILM MANUFACTURING EUROPE BV;TECHNISCHE UNIVERSITEIT EINDHOVEN;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK;UNIVERSITY OF ULSTER";"BE;UK;DE;NL;FR;IE";/LIF;1;0;0;1;0;0 110361;607616;IN-SENS;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-ITN;FP7;Deciphering inter- and intracellular signalling in schizophrenia;2013-10-01;2017-09-30;;"IN-SENS is an interdisciplinary, cutting-edge European industry-academia collaborative effort for a novel training of scientists in molecular psychiatry with the prospect of discovering the biology of schizophrenia and actively promote drug discovery. Mental illnesses are a major burden to patients, relatives, and public health worldwide. IN-SENS therefore aims to profoundly change the academic-industry research landscape in European psychiatry by an unprecedented, innovative strategy. The extended intra- and intercellular signalling pathway of disrupted-in-schizophrenia 1 (DISC1), the best characterized gene known to cause schizophrenia and other chronic mental illnesses (CMI), will be used as a molecular Rosetta stone for this purpose. Expected results of IN-SENS include profound training, including clinical psychiatry, industrial, and translational medicine exposure, of a new generation of European ESRs capable of understanding the molecular underpinnings of CMI in academia, industry and other non-academic sectors. ESRs will explore how molecules related to the extended DISC1 pathway translate to the different biochemical, genetic, and neurodevelopmental hypotheses and data proposed so far as being important players in the molecular pathology of CMI. Further, they will play an active role in the generation of new analytical tools and therapeutic agents for the diagnosis and treatment of CMI in close collaboration with the industrial sector. IN-SENS will have immediate and longterm benefits for the European academic-industry research landscape in psychiatry by fostering scientific creativity and entrepreneurial skills of ESRs, generating novel research networks in Europe, enhancing mutual recognition and introducing novel models and of public-private cooperations. At the end of IN-SENS, exceptionally trained ESRs will be ready to extend these studies in academia and/or the private sector, and be able to move confidently to a fruitful professional career.";3918138;3918138;FP7-PEOPLE-2013-ITN;/MC-ITN;HEINRICH-HEINE-UNIVERSITAET DUESSELDORF;DE;"Institute of Science and Technology Austria;LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN;HELSINGIN YLIOPISTO;KUNGLIGA TEKNISKA HOEGSKOLAN;STICHTING VU;IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE;ASTRAZENECA AB;F. HOFFMANN-LA ROCHE AG;UNIVERSITEIT MAASTRICHT;UNIVERSIDAD DE SANTIAGO DE COMPOSTELA;SYNAPTOLOGICS BV;THE UNIVERSITY OF EDINBURGH";"AT;DE;FI;SE;NL;UK;CH;ES";/LIF;1;0;0;1;0;0 191150;609102;PRESTIGE;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-COFUND;FP7;PRES Towards International Gain of Excellence;2014-09-01;2019-08-31;;"The programme PRESTIGE stands for PRES Towards International Gain of Excellence. It is a grant programme which main aim is to attract foreign researchers to do research work and undertake training in various institutions of the Clusters (PRES) of the two participating French Regions: Region Rhône-Alpes and Region Midi-Pyrénées. Its goal is also to send abroad some of the promising young researchers, from the two Regions, so that they participate in international research activities at the highest level. PRESTIGE is based on incoming and outgoing mobility initiatives that already exist in the Regions, participating in the proposal, but combines them into an innovative programme of much larger size covering a very broad range of research fields. It helps to create a network enabling the research fellow to choose freely the research topic, destination and research group and favours with cross-fertilization exchanges between researchers. PRESTIGE has the following main objectives of: • Promoting interdisciplinary research cooperation with young talents; • Boosting employment in R&D; • Increasing the competitiveness of the participating Regions; • Increasing the visibility at international level of regional initiatives so as to structure the European Research Area (ERA). PRESTIGE is composed of the following partners: • Campus France, the Coordinator; • CPU, the Conference of French Rectors; • The Region Rhône-Alpes and its Clusters of Higher Education and Research (PRES) called “Université de Grenoble” and “Université de Lyon”; • The Région Midi-Pyrénées and its Cluster of Higher Education and Research (PRES) named “Université de Toulouse”. PRESTIGE is planned for 5 years (4th quarter 2013 – 4th quarter 2018) and is based on an academic duration of four years (four main calls for fellows will be launched). The programme has an overall budget of 24 944 000 €, 60% of which will be financed by regional sources, public bodies and private companies.";15086620;6034648;FP7-PEOPLE-2013-COFUND;/MC-COFUND;CAMPUS FRANCE;FR;;;/LIF;1;0;0;1;0;0 109117;334322;ACLACL;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-CIG;FP7;Anchoring the Consumer: Legitimacy and Accountability in Competition Law;2013-11-01;2018-10-31;;This proposal offers interdisciplinary, empirical and comparative research into the legitimacy and accountability problems facing EU competition law. EU competition law has gone through a significant reform process orchestrated by the European Commission. The Commission’s overarching goal in this process was to place ‘consumer welfare’ at the centre of the enforcement of competition rules. In contrast to the strong consumer focus in the design of substantive rules, consumers play a very limited role in the process of the making and enforcement of EU competition rules. Firstly, institutions representing consumer/citizen interests, such as the European Parliament and civil society, have been largely absent in the process leading to reforms. Secondly, the reforms increased economic technicality and the Commission’s administrative discretion in the enforcement of competition rules at the expense of judicial and parliamentary oversight. The limited ex ante consumer participation jeopardises the legitimacy of EU competition law, whereas the limited ex post judicial and parliamentary control impedes accountability. The voluminous law and economics literature of competition law focuses almost exclusively on substantive questions, turning a blind eye to legitimacy and accountability problems. Against this background, the proposed project will study the legitimacy and accountability problems in EU competition law and potential solutions for these problems using delegation theory as the main analytical framework. For methodology, the project will use empirical research of the role of consumer organisations and parliamentary committees, legal analysis of judicial review standards, and comparative research of the US antitrust regime that provided the main inspiration for the reform agenda. By filling an important gap in the literature, the project will contribute to developing mechanisms for firmly anchoring consumers in the making and enforcement of EU competition rules.;100000;100000;FP7-PEOPLE-2012-CIG;/MC-CIG;THE UNIVERSITY OF LIVERPOOL;UK;;;/LIF;1;0;0;1;0;0 108054;600377;CERN-COFUND-2012;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-COFUND;FP7;COFUNDing of the CERN Fellowship Programme 2012;2013-10-01;2018-09-30;;"For many years, CERN has operated a trans-national Fellowship programme, offering scientists and engineers challenging opportunities in particle physics research, and in related fields of physics and technology. CERN secured COFUND grants in 2008, 2010 and 2011. They offer CERN a timely opportunity to enhance the mobility element of this programme without nationality limitations. The 2012 Call comes at a time when the start-up of the Large Hadron Collider has made CERN one of the most exciting places to work for the global physics and technology community. Applicants will propose their own research projects. Selection will be based on the scientific potential of the proposal, and on the demonstrated excellence of the candidate. Working on frontier research and technology projects and profiting from the unique facilities available at CERN, the co-funded Fellows will deepen their knowledge in their own field and acquire international visibility and reputation. They will broaden their skills using the numerous training opportunities and through their exposure to an interdisciplinary and multi-national environment. Inter-sectoral skills will be fostered through CERN’s industrial collaborations and technology transfer projects. Employment conditions will be improved by offering three-year appointments rather than the standard two-year terms of CERN Fellows. At least two of these three years will be spent at CERN. We consider this provision to be justified by the size of the Laboratory, the diversity of the research and training opportunities, and by the uniqueness of CERN’s facilities. However, mobility will be enhanced through the opportunity to spend up to one third of the Fellowship in external institutions, including industrial laboratories, on secondment from CERN under the conditions of the full employment contract. These improvements, enabled by the COFUND action, will further increase the competitiveness of CERN’s Fellowship Programme.";20000014,32;8000005,73;FP7-PEOPLE-2012-COFUND;/MC-COFUND;EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH;CH;;;/LIF;1;0;0;1;0;0 89032;231323;CYBEREMOTIONS;CLO;FP7-ICT;ICT-2007.8.4;FP7;Collective Emotions in Cyberspace;2009-02-01;2013-05-31;;The main aims of the project are:- to understand the process of collective emotions formation in e-communities as a spontaneous emergent behaviour occurring at complex techno-social networks- to create decentralized adaptive tools to amplify positive or suppress negative collective emotions in e-societies and will take into account heterogeneity of interacting humans- to create theoretical background for the development of the next generation emotionally-intelligent ICT services using models of self-organized active agents models, and sociophysics methods.
The project focuses on the role of collective emotions in creating, forming and breaking-up of e-communities. Understanding these phenomena is important in view of the growing role of ICT-mediated social interactions and specific features of e-communities.
The challenge of this interdisciplinary project is to combine both: psychological models of emotional interactions and algorithmic methods for detection and classification of human emotions in the Internet with probabilistic models of complex systems and data driven simulations based on heterogeneous emotionally reacting agents approach. Theoretical foundations will mainly base on statistical physics applied for study of emergent properties of many-object systems interacting in self-organized evolving networks.Empirically, we concentrate on the issue of how to support and maintain emotional climates of security, trust, hope, and freedom in future techno-social communities and how to prevent and resolve conflicts in them. Data on human emotions as well as on their influence on the structure of sustainable cooperative communities will be received from Blogoshere, newsgroups and Internet discussion forums and compared to computer simulations based on active agents models. Finally, we plan to develop artificial agents that can help to influence emotional states of the members of e-communities and can act as cyber-advisers.;4636660;3600000;FP7-ICT-2007-3;/CP;POLITECHNIKA WARSZAWSKA;PL;"GEMIUS SPOLKA AKCYJNA;UNIVERSITY OF WOLVERHAMPTON;INSTITUT JOZEF STEFAN;JACOBS UNIVERSITY BREMEN GGMBH;ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE;TECHNISCHE UNIVERSITAT BERLIN;EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH;OSTERREICHISCHE STUDIENGESELLSCHAFTFUR KYBERNETIK VEREIN";"PL;UK;SI;DE;CH;AT";"/ELM;/IPS;/SOC;/TEL";1;0;0;1;0;0 88971;231167;CONNECT;CLO;FP7-ICT;ICT-2007.8.6;FP7;Emergent Connectors for Eternal Software Intensive Networked Systems;2009-02-01;2012-11-30;;"The CONNECT Integrated Project aims at enabling continuous composition of networked systems to respond to the evolution of functionalities provided to and required from the networked environment. At present the efficacy of integrating and composing networked systems depends on the level of interoperability of the systems' underlying technologies. However, interoperable middleware cannot cover the ever growing heterogeneity dimensions of the networked environment. CONNECT aims at dropping the interoperability barrier by adopting a revolutionary approach to the seamless networking of digital systems, that is, synthesizing on the fly the connectors via which networked systems communicate. The resulting emergent connectors are effectively synthesized according to the behavioral semantics of application- down to middleware-layer protocols run by the interacting parties. The synthesis process is based on a formal foundation for connectors, which allows learning, reasoning about and adapting the interaction behavior of networked systems at run-time. Synthesized connectors are concrete emergent system entities that are dependable, unobtrusive, and evolvable, while not compromising the quality of software applications. To reach these objectives the CONNECT project undertakes interdisciplinary research in the areas of behavior learning, formal methods, semantic services, software engineering, dependability, and middleware. Specifically, CONNECT will investigate the following issues and related challenges: (i) Modeling and reasoning about peer system functionalities, (ii) Modeling and reasoning about connector behaviors, (iii) Runtime synthesis of connectors, (iv) Learning connector behaviors,(v) Dependability assurance, and (vi) System architecture. The effectiveness of CONNECT research will be assessed by experimenting in the field of wide area, highly heterogeneous systems where today's solutions to interoperability already fall short (e.g., systems of systems of systems).";6438956;4819875;FP7-ICT-2007-3;/CP;INSTITUT NATIONAL DE RECHERCHE ENINFORMATIQUE ET AUTOMATIQUE;FR;"DOCOMO COMMUNICATIONS LABORATORIES EUROPE GMBH;THALES SIX GTS FRANCE SAS;UPPSALA UNIVERSITET;TECHNISCHE UNIVERSITAT DORTMUND;UNIVERSITA DEGLI STUDI DELL'AQUILA;CONSIGLIO NAZIONALE DELLE RICERCHE;LANCASTER UNIVERSITY;AMBIENTIC SAS;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;PEKING UNIVERSITY";"DE;FR;SE;IT;UK;CN";"/ELM;/IPS;/SOC;/TEL";1;0;0;1;0;0 91502;238597;ICTeCollective;CLO;FP7-ICT;ICT-2007.8.0;FP7;Harnessing ICT-enabled collective social behaviour;2009-10-01;2012-09-30;;The last decades have seen a tremendous change of society as a whole, driven by Information and Communication Technologies (ICT). The dynamics of building and strengthening social relationships have evolved through the use of ICT, and new ICT-mediated groups and communities have emerged. Individuals, communities, society, and ICT have become deeply intertwined in a dynamic feedback process. The fundamental challenge for future social ICT is overcoming the acute lack of understanding of the driving forces and mechanisms of this complex system of interactions. The project aims to develop systematic exploration, understanding, and modelling of systems where ICT is entangled with social structures. Currently, there is no general understanding, either at the individual or collective level, of how ICT-mediated social interactions and patterns of influence work. In particular, there is a critical gap in our understanding of how different levels of social behaviour are related to each other. Moreover, the existing knowledge in this area is highly fragmented between different scientific disciplines such as social psychology, computer science, and complexity science. A major goal of ICTeCollective is to bridge this gap, by using multi-level and multi-scale approaches to understand ICT mediated social dynamics at a societal level in relation to micro- and meso-scale processes. This goal will be achieved by carrying out original experiments on the impact of ICT on human behaviour, analysing ICT-generated large, unique, and time-stamped datasets, constructing and investigating models and building up a more general theoretical framework. This interdisciplinary approach of ICTeCollective will produce new insight and integrate the fragmented knowledge of different scientific disciplines concerning social aspects and consequences of ICT into a coherent form, which is amenable to be used in policy-making decisions and of benefit to the industry.;2565237;1946214;FP7-ICT-2009-C;/CP;AALTO KORKEAKOULUSAATIO SR;FI;"UNIWERSYTET WARSZAWSKI;BUDAPESTI MUSZAKI ES GAZDASAGTUDOMANYI EGYETEM;Teknillinen korkeakoulu;ISTITUTO PER L'INTERSCAMBIO SCIENTIFICO;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD";"PL;HU;FI;IT;UK";"/ELM;/IPS;/TEL";1;0;0;1;0;0 185726;621329;ISO-FOOD;ONG;FP7-REGPOT;ERACHAIRS-2013-1;FP7;ERA CHAIR FOR ISOTOPE TECHNIQUES IN FOOD QUALITY, SAFETY AND TRACEABILITY;2014-07-01;2019-06-30;;The “ISO-FOOD” ERA Chair for isotope techniques in food quality, safety and traceability will act as an independent Centre hosted by the Jožef Stefan institute (JSI), which will be a sustainable and leading research and educational institution in the field of food (including fodder and forage) analysis in the region, embedded into the national and European research area through collaboration with international partner organizations and stakeholders. To advance the knowledge of food quality, safety and traceability, the research activities of the ERA Chair will focus on interdisciplinary topics combining the expertise in radiochemistry, stable isotope biogeochemistry, electron microscopy and microanalysis and combined analytical techniques (e.g. organic compound profiling, NMR chemical profiling), as well as multivariate statistics and data management, to develop universally available analytical strategies to verify the origin (provenance) of agricultural produces and foodstuffs, agricultural practices, food contamination, contamination sources and their safety. Nuclear and nuclear-related techniques for food traceability, which are tailored for fingerprinting of food provenance and authenticity, will be developed and combined with elemental markers and biomarkers. Existing databases of authentic food products will be upgraded and extended. The ERA Chair will harvest the knowledge and excellence of four JSI Departments, two centres of Excellence coordinated by the JSI and capacities of the Jožef Stefan International Postgraduate School, which will perform the new doctoral study programme on Food Science, developed by the ERA Chair, in collaboration with international academic institutions. ISO-FOOD will collaborate with national stakeholders and decision makers, providing knowledge and means for bridging the gap between the fields of economic and spatial development, and, on the other side, environmental and national health.;2624710,64;1842818;FP7-ERAChairs-PilotCall-2013;/CSA-SA;INSTITUT JOZEF STEFAN;SI;;;;1;0;0;1;0;0 186087;624739;PlantMYCcellWall;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IOF;FP7;Plant genetic determinants controlling arbuscular mycorrhizal fungal growth through the plant cell wall;2015-01-01;2018-04-22;;Arbuscular mycorrhizal (AM) symbiosis has great potential in agriculture for the development of food and energy crops better equipped to cope with extreme environmental conditions and with less fertilizers requirement. PlantMYCcellWall intends, through an interdisciplinary research project using a combination of genetics, molecular, cell biology and biochemical approaches, a better understanding of the plant molecular basis regulating the AM symbiosis development. Despite significant advances in understanding the mechanism controlling the mycorrhizal symbiosis, we still do not really understand how plants influence the fungal growth through the plant cell wall, and how the AM fungus is able to cross the plant cell wall. Accordingly, the principles aims of PlantMYCcellWall, are to address a previously unexplored but timely area on plant cell wall modifications during AM symbiosis and on the plant genetic determinants and hormonal signaling that regulate the AM fungus growth through the plant cell wall. The recently described Brachypodium mycorrhizal plant interaction, presents an exclusively intracellular growth being crucial to aboard this research. In our endangered plant productivity environment, deciphering these mechanisms in Brachypodium plants will allow us to know if important European cereals crops as wheat and barley will benefit from the AM symbiosis in a more sustainable agriculture. Results obtained in PlantMYCcellWall will enhance the actual knowledge in AM symbiosis allowing a better use of soil resources with a better crop performance and will also provide valuable knowledge for the pathogenic community. By combining the different approaches proposed, PlantMYCcellWall will generate new knowledge that will open new avenues for the understanding of mechanisms controlling plants symbiosis and opening up new interesting fields of study of plant-microbe interactions.;265263,3;265263,3;FP7-PEOPLE-2013-IOF;/MC-IOF;CENTRE DE RECERCA EN AGRIGENOMICA CSIC-IRTA-UAB-UB;ES;;;/LIF;1;0;0;1;0;0 109279;607400;TRAX;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-ITN;FP7;Training network on tRAcking in compleX sensor systems;2013-10-01;2017-09-30;;"In today’s society, massive amounts of electronic sensors surround us that are tracking objects for the purpose of healthcare, surveillance, retail oriented commercial purposes and many others. Modern sensors generate very large amounts of data, however, due to current technical limitations, it is nearly impossible to integrate large scale data from many different and complex sensors to track very large groups of objects and people. Major advancements in various important areas in our society, such as traffic and crowd management, movement science in healthcare, smart surveillance, security and defense are hindered by this limitation, slowing down European industrial growth. The Training programme on Tracking in Complex Sensor Systems (TRAX) project aims to investigate and design innovative algorithms and techniques for dealing with raw data from complex and advanced tracking systems. This will be achieved through the establishment of a novel research training programme on Tracking in Complex Sensor Systems, covering interdisciplinary and intersectoral aspects in this newly emerging supra-disciplinary field. The TRAX consortium comprises two large companies (Thales Nederland B.V., Ericsson A.B.); two SMEs (Rinicom Limited, Xsens Technologies B.V.); a research institute ( Fraunhofer) and three universities (University of Lancaster, Linköping University and University of Twente); and is supported by two associated partners: SME SenionLab A.B. and University of Bonn. 12 early stage researches and 3 experienced researchers get the opportunity to work on the state-of-the-art complex tracking field. The uniqueness of TRAX is that while all research is being performed under one umbrella, it is being exploited by different branches of industry and implemented in various applications, resulting in significant benefits for EU industry and society and delivering highly wanted, currently scarcely available, young researchers in the multidisciplinary field of complex tracking.";4127431,67;4127431,67;FP7-PEOPLE-2013-ITN;/MC-ITN;THALES NEDERLAND BV;NL;"LINKOPINGS UNIVERSITET;XSENS TECHNOLOGIES B.V.;UNIVERSITY OF SHEFFIELD ROYAL CHARTER;FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.;UNIVERSITEIT TWENTE;RINICOM LIMITED;ERICSSON AB";"SE;NL;UK;DE";/LIF;1;0;0;1;0;0 102369;290568;ACCRETE;ONG;FP7-IDEAS-ERC;ERC-AG-PE10;FP7;Accretion and Early Differentiation of the Earth and Terrestrial Planets;2012-05-01;2018-04-30;;Formation of the Earth and the other terrestrial planets of our Solar System (Mercury, Venus and Mars) commenced 4.568 billion years ago and occurred on a time scale of about 100 million years. These planets grew by the process of accretion, which involved numerous collisions with smaller (Moon- to Mars-size) bodies. Impacts with such bodies released sufficient energy to cause large-scale melting and the formation of deep “magma oceans”. Such magma oceans enabled liquid metal to separate from liquid silicate, sink and accumulate to form the metallic cores of the planets. Thus core formation in terrestrial planets was a multistage process, intimately related to the major impacts during accretion, that determined the chemistry of planetary mantles. However, until now, accretion, as modelled by astrophysicists, and core formation, as modelled by geochemists, have been treated as completely independent processes. The fundamental and crucial aim of this ambitious interdisciplinary proposal is to integrate astrophysical models of planetary accretion with geochemical models of planetary differentiation together with cosmochemical constraints obtained from meteorites. The research will involve integrating new models of planetary accretion with core formation models based on the partitioning of a large number of elements between liquid metal and liquid silicate that we will determine experimentally at pressures up to about 100 gigapascals (equivalent to 2400 km deep in the Earth). By comparing our results with the known physical and chemical characteristics of the terrestrial planets, we will obtain a comprehensive understanding of how these planets formed, grew and evolved, both physically and chemically, with time. The integration of chemistry and planetary differentiation with accretion models is a new ground-breaking concept that will lead, through synergies and feedback, to major new advances in the Earth and planetary sciences.;1826200;1826200;ERC-2011-ADG_20110209;/ERC-AG;UNIVERSITAET BAYREUTH;DE;;;"/PSE;/ENV;/EAR";1;0;0;1;0;0 107368;323943;HUMVOL;ONG;FP7-IDEAS-ERC;ERC-AG-SH4;FP7;Human Volition, Agency and Responsibility;2013-06-01;2018-05-31;;"At the heart of human nature lies the idea of a free agent, whose conscious thoughts and decisions motivate their voluntary actions, and who is therefore responsible for what they do. Voluntary actions can be defined as actions that an individual agent generates internally, rather than in response to any environmental event. However, the concept of voluntary action remains controversial, and lacks a scientific evidence base. Neuroscience rejects dualistic notions of ‘conscious free will’, and instead views actions as products of mechanistic brain processes, which are often unconscious. Thus, volition is often eliminated from psychology, or replaced with alternative, more behaviourist formulations such as ‘executive function’, or ‘reward-directed action’. However, the generative quality of human action, and the strong subjective experience of agency and responsibility for one’s own actions, still require scientific investigation. Even if we may not have conscious free will as envisaged, cognitive neuroscience has acquired appropriate methods to investigate and measure what we do have, and to explore implications for society. HUMVOL therefore aims to investigate scientifically the neural bases of human volition (Work Package WP1), agency (WP2) and responsibility (WP3). Subjective aspects are not neglected, because they may offer powerful cues to the mechanisms and functions of voluntary action. The core methods are behavioural, psychophysical and neural experiments with healthy volunteers. EEG and fMRI will allow direct measures of brain processes associated with volition, while subliminal priming and non-invasive brain stimulation will allow their direct manipulation. Mental chronometry and explicit agency judgements allow the impact of these processes on subjective experience to be assessed. Finally, interdisciplinary engagements will focus on how neuroscientific evidence could influence societal concepts of voluntary action, particularly in the Law.";1984927;1984927;ERC-2012-ADG_20120411;/ERC-AG;UNIVERSITY COLLEGE LONDON;UK;;;/MED;1;0;0;1;0;0 85533;215056;PICOS;CLO;FP7-ICT;ICT-2007.1.4;FP7;Privacy and Identity Management for Community Services;2008-02-01;2011-06-30;;"With the emergence of services for professional and private on-line collaboration via the Internet, many European citizens spend work and leisure time in on-line communities. Users consciously leave private information; they may also leave personalized traces they are unaware of. PICOS will develop and build a state-of-the-art platform for providing the trust, privacy and identity management aspects of community services and applications on the Internet and in mobile communication networks. The PICOS approach to trustworthy on-line community collaboration addresses these four questions: What are the Trust, Privacy and Identity issues in new context-rich mobile communication services, especially community-supporting services? How can information flows and privacy requirements be balanced in complex distributed service architectures (e.g., mash-ups)? How can these issues be solved in an acceptable, trustworthy, open, scalable, manner? Which supporting services and infrastructures do the stakeholders need?The PICOS consortium includes European industry and research communities. The project will first review contemporary research in relevant disciplines. Its platform design and prototype development work will then create interoperable, open, privacy-respecting identity and trust management tools that can be demonstrated to the public. These will be used to construct community application prototypes by leading industry partners; those will be trialled with selected on-line communities. PICOS will self-evaluate usability, ergonomics, legal issues, trust and privacy. Expected PICOS results are:•A set of interdisciplinary requirements for trustworthy, privacy-friendly community transactions,•A platform prototype that demonstrates the provision of state-of-the-art privacy and trust technology to community applications,•User-centric trials that validate its applicability,Publications and a final report will disseminate the PICOS results to the public.";5957801;3999995;FP7-ICT-2007-1;/CP;JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN;DE;"T-MOBILE INTERNATIONAL AG;IT-OBJECTS GMBH;Masarykova univerzita;HEWLETT PACKARD CENTRE DE COMPETENCES FRANCE;ATOS SPAIN SA;HEWLETT-PACKARD LIMITED;CURE CENTRUM FUR DIE UNTERSUCHUNG UND REALISIERUNG ENDBENUTZERORIENTIERTER INTERAKTIVER SYSTEME;LEIBNIZ-INSTITUT FUER MEERESWISSENSCHAFTEN AN DER UNIVERSITAET KIEL;UNIVERSIDAD DE MALAGA;KATHOLIEKE UNIVERSITEIT LEUVEN;DEUTSCHE TELEKOM AG";"DE;CZ;FR;ES;UK;AT;BE";"/ELM;/IPS;/TEL";1;0;0;1;0;0 87854;217751;CARBOSCHOOLS+;ONG;FP7-SIS;"SiS.2007-2.2.1.2;SiS-2007-2.2.1.1";FP7;European network of regional projects for school partnerships on climate change research;2008-01-01;2010-12-31;;"CarboSchools\ proposes to link carbon science laboratories with secondary schools to develop partnerships where young Europeans learn and conduct experiments about climate research and reduction of greenhouse gas emissions. In partnership projects, scientists and teachers co-operate over several months to give young people a practical experience of research through real-time experiments, site visits, debates etc. A final output (article, exhibition) shares the findings with parents, friends, community etc. Nine research institutes in 7 countries will explore how they can best motivate and support such partnerships at the regional level in a wide variety of contexts, approaches, topics and age-groups. European co-operation will allow a comparison of results, learn from each other and develop replicable good practice. Pupils will gain European experience by doing comparative measurements through a common “school CO2-web”. An in-depth study of impacts on attitudes, beliefs and skills will allow a better understanding of the projects' level of effectiveness. Over 2 school years, partnerships will involve about 90 scientists, 140 teachers and more than 3000 students. Their direct interaction will support teachers in the highly complex, interdisciplinary and socially relevant field of global change, and improve the communication skills of scientists. Methods and materials will be jointly developed and shared with a broad range of players in science education via the internet, a European conference and regional dissemination activities. CarboSchools\ is proposed by institutes firmly rooted in two FP6 research projects on climate change on the basis of outstanding results from educational projects piloted since 2005. A field-tested concept, a first set of resources and an enthusiastic human network provides us with confidence and institutional support to make science learning more engaging and challenging for young people as future workers, consumers and citizens.";1426197,91;981553;FP7-SCIENCE-IN-SOCIETY-2007-1;/CSA-CA;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;DE;"TEACHER SCIENTIST NETWORK LBG;FUNDACIO PARC CIENTIFIC DE BARCELONA;COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES;CONSIGLIO NAZIONALE DELLE RICERCHE;LEIBNIZ-INSTITUT FUER MEERESWISSENSCHAFTEN AN DER UNIVERSITAET KIEL;RIJKSUNIVERSITEIT GRONINGEN;INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;UNIVERSITETET I BERGEN";"UK;ES;FR;IT;DE;NL;NO";"/SCI;/EDU";1;0;0;1;0;0 90821;221073;LAND CRAB OLFACTION;ONG;FP7-PEOPLE;PEOPLE-2007-2-1.IEF;FP7;Transition from sea to land: Olfactory function and adaptations in terrestrial crustaceans;2009-07-01;2011-06-30;;Within adult anomuran land crabs (Coenobitidae: Anomura) there are various degrees of terrestrialization, but all species have retained marine larval stages. The ability to recognize and discriminate chemical cues in the environment is essential for most animals, and thus a successful transition from sea to land calls for dramatically new demands on the chemosensory system, where stimulus changes from mainly water-soluble molecules to hydrophobic, volatile chemical cues carried by the air. Hence, these land crabs represent an excellent opportunity to investigate the effects of the transition from sea to land on the olfactory system. The olfactory organs of Coenobitidae show structural similarities with the insects, indicating an adaptation for function in air and both field and laboratory studies show that land crabs do make use of their olfactory system on land and seem to have quite sophisticated olfactory abilities for distant chemoreception. Also new neuroanatomical studies indicate that the coenobitids have superb olfactory processing and discrimination capacities. The main objective of this research project is to explore the seemingly extraordinary olfactory abilities of the Coenobitidae and to understand how they have evolved as adaptations to the terrestrial environment. In a highly interdisciplinary approach, behavioural investigations will be integrated with modern neurophysiological and optical imaging techniques, to identify which chemical substances induce biological activity and to study olfactory processing and discrimination capabilities. The project will generate new knowledge about how environmental and evolutionary forces dictate specific adaptations in olfactory systems, which will contribute to our general understanding of the olfactory sense. The high complementarity of the research training will strongly reinforce my scientific career by broadening my research perspective while at the same time adding cutting edge focus.;166982,27;166982,27;FP7-PEOPLE-2007-2-1-IEF;/MC-IEF;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;DE;;;"/SCI;/EDU";1;0;0;1;0;0 107484;330699;INNOVANTI;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IEF;FP7;Innovative tools to examine the development of antisocial behaviour from early childhood to adolescence: Genetically informative designs and propensity score matching;2013-10-15;2015-10-14;;"Antisocial behaviour is a substantial problem in Europe: detrimental to victims, the youth, families and society as a whole. Among promising research avenues are the use of genetically informative longitudinal studies, as well as research designs aimed to determine which predictors of antisocial behaviour are causative. Using such innovative designs, my primary purpose is to provide a better understanding of the development of antisocial behaviour from early childhood to adolescence and its predictors, which will help to identify important targets for intervention and will provide an indication of when best to intervene. I will use the Twins Early Development Study (TEDS), a unique data set of 10000 pairs of twins born between 1994 and 1996 and followed from 2 to 16 years. The present project comprises 3 complementary objectives: (1) identify childhood disorder symptoms uniquely predicting adolescent delinquency and identify the genetic and environmental contribution in the prediction; (2) verify whether harsh parental discipline and peer victimization play a causal role in the prediction of antisocial behaviour; (3) determine at which age and for which populations (e.g. disadvantaged populations) heritable or environmental components play a greater role in antisocial behaviour. I will use advanced statistical modelling, namely by combining twin modelling with propensity score matching. The present project will generate new knowledge with both innovative techniques and a data set of unique quality. As such, the project is both innovative and timely. So far, I have received interdisciplinary training in a world leading research team specialising in antisocial behaviour, which has resulted in high impact publications. With the proposed fellowship, I will benefit from outstanding specialised training and mentoring, which will be crucial to establish myself as an independent researcher and contribute to the excellence of the European Research Area.";221606,4;221606,4;FP7-PEOPLE-2012-IEF;/MC-IEF;UNIVERSITY COLLEGE LONDON;UK;;;/SCI;1;0;0;1;0;0 101761;290344;EUROTAST;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-ITN;FP7;A European Initial Training Network on the History, Archaeology, and New Genetics of the Trans-Atlantic Slave Trade;2011-11-01;2015-10-31;;The principal aim of this ITN is to examine the history of the transatlantic slave trade and its legacies from a variety of different angles. The idea is to hire thirteen Early Stage Researchers (ESRs) and two Experienced Researchers (ERs) across Europe and a wide range of disciplines, including history, archaeology, sociology, heritage studies and genetics, to investigate various aspects of the slave trade and its legacies today. By bringing in experts from these various fields, including some that are not traditionally associated with slave trade research, such as genetics, we hope to contribute new data that will add to our knowledge of how the slave trade operated and how it impacted on the lives of millions of people. Furthermore, we believe that this setup presents a unique opportunity to deliver a training package that will encourage interdisciplinary thinking and help us to bridge the gap between what C.P. Snow called the “two cultures” of modern society - the sciences and the humanities.2 Working together on a common theme, a team of historians, archaeologists, sociologists and ge- neticists will examine various aspects of the slave trade that will increase our understanding of this horrific period in our history and, thus, help us to come to terms with it. Last but not least, we aim to disseminate the results of our various projects as widely as possible and we believe that the unique combination of history and science will en- able us to reach a much broader spectrum of the general public than hitherto possible.;4304064;4304064;FP7-PEOPLE-2011-ITN;/MC-ITN;KOBENHAVNS UNIVERSITET;DK;"UNIVERSITEIT LEIDEN;IPATIMUP - INSTITUTO DE PATOLOGIA E IMUNOLOGIA MOLECULAR DA UNIVERSIDADE DO PORTO PCUP;ISLENSK ERFDAGREINING EHF;UNIVERSIDAD DE SANTIAGO DE COMPOSTELA;UNIVERSITY OF YORK;UNIVERSITY OF HULL;UNIVERSITY OF BRISTOL;UNIVERSITE PAUL SABATIER TOULOUSE III;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS";"NL;PT;IS;ES;UK;FR";"/LIF;/SCI";1;0;0;1;0;0 92668;237909;SYSFLO;ONG;FP7-PEOPLE;FP7-PEOPLE-ITN-2008;FP7;Training in Systems Biology Applied to Flowering;2009-12-01;2013-11-30;;We will educate and train young scientists to apply an interdisciplinary systems-based approach to complex biological questions using plant reproduction as a model system. Systems approaches are not routinely taught, have been identified as an area requiring urgent PhD-level training in some European countries and require network-scale working practices. We have assembled a team with International research reputations in two key areas for the success of this project: half are experimental and half are computational/mathematical scientists. We will place 9 PhD students under the supervision of this team, focussed on this single biological problem. Students assigned to experimental groups will use advanced techniques to generate data for the computational groups. The computational students will inform, analyse, interpret and model the data and their models will be validated by the experimental groups. A series of laboratory placements will ensure a wide range of subject-specific training and exchanges between the experimental and computational groups will lead to a greater understanding at the interface of these disciplines. The integration of a team of PhD students into this project, so that they each see their contributions as essential and integral parts of the success of the strategy, combined with the supervison and co-ordinated discipline-specific and generic training schedule will produce a cohort of young scientists trained in systems biology. The core skills and approaches that will be instilled into the young scientists and the integration of industry into the project, will equip them to take a systems approach to any biological question and prepare them for a career in an academic or industrial environment. Scientific outcomes will include the use of advanced techniques to provide the quantity and quality of data required to model floral regulation, the use of computational approaches to generate predictive models and their experimental validation.;1905648;1905648;FP7-PEOPLE-ITN-2008;/MC-ITN;UNIVERSITY OF LEEDS;UK;"MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;BIOBASE GMBH;JOHN INNES CENTRE;VIB;UNIVERSITA DEGLI STUDI DI MILANO;INSTYTUT GENETYKI ROSLIN POLSKIEJ AKADEMI NAUK;STICHTING WAGENINGEN RESEARCH";"DE;UK;BE;IT;PL;NL";"/SCI;/EDU";1;0;0;1;0;0 94888;255624;THECOSINT;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IEF;FP7;Theory of Quantum Computation and Many-Body Simulation with Novel Quantum Technologies;2011-01-31;2013-01-30;;The recently emerged discipline of quantum information promises to have a profound impact on the information technologies that so deeply permeate our society. The search for an actual quantum information processor involves different physical systems, thus motivating an exciting interdisciplinary research ground. In this framework the present project will involve contributions from various branches of quantum science, with emphasis to cutting-edge quantum technologies in condensed matter and quantum optical systems. The project -besides enhancing the competence diversification of the candidate- is properly tailored for his scientific trajectory which, starting from investigations on quantum information and quantum optics, aims at progressively acquire expertise in the field of many-body systems. This, in turn, is expected to strongly support the candidate in attaining a leading independent position. Specifically, the main objective of the project is to investigate theoretically novel approaches to quantum simulators (QS) and quantum computation (QC) properly tailored for new quantum technologies. The two major quantum information paradigms will be considered: discrete and continuous variables. The first goal is to individuate the benefits offered by novel technologies such as circuitQED, microcavities, and nano-elecromechanical oscillators. Then these technologies will be exploited to find novel proposals for QS of strongly interacting many-body systems (both spin and bosonic systems). The presence of thermal noise will be addressed by using new ideas emerged in the field of quantum thermodynamics. Finally, the last goal is the search for new continuous variable schemes for QC. We will focus on measurement based QC, a new computation paradigm which exploits the synergies between quantum information and many-body systems. To face the drawbacks that historically affect continuous variable QC the benefits offered by the above mentioned technologies will be harnessed.;165540,8;165540,8;FP7-PEOPLE-2009-IEF;/MC-IEF;UNIVERSITY COLLEGE LONDON;UK;;;"/SCI;/EDU;/ITT";1;0;0;1;0;0 101714;289966;BEAN;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-ITN;FP7;BEAN – Bridging the European and Anatolian Neolithic: Demography, Migration, and Lifestyle at the Advent of Civilization;2012-02-01;2016-01-31;http://beanproject.eu/;"One of the most interesting questions in prehistory is that of the origins of European peoples following the introduction of settled farming life to the continent some 8,000 years ago. The interdisciplinary BEAN network will address this by combining teaching and research in three different fields: i) Anthropology and genetics, ii) computer simulation and modelling, and iii) prehistoric archaeology. Particularly, it will provide state of the art training in palaeo-genomics, mathematical modelling of prehistoric culture change and statistical demographic inference methods. The network includes one industrial and seven academic participants and five associates and will incorporate an integrated educational system that combines intensive specialized training in each subject and rotation of early stage and advanced researchers. This research has wider impact, for example within the multibillion-euro cultural heritage industry, and BEAN will include internships at three private sector partners; a biotech company, a tourist company and a publisher, as well as the German national statistics office. Thus, participants will engage with cutting edge scientific methods, will combine diverse disciplines and schools of thought and will be guaranteed contact with private companies and state organisations for further career development. Additionally, there will be a special focus on translational skills, particularly media relations and scientific writing, both of which will feed into the final “BEAN-book”, which will be co-authored by ESRs, ERs and PIs, and published by Springer.";2535750,54;2535750,54;FP7-PEOPLE-2011-ITN;/MC-ITN;JOHANNES GUTENBERG-UNIVERSITAT MAINZ;DE;"THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN;UNIVERSITE DE GENEVE;EUROFINS GATC BIOTECH GMBH;Istanbul University;UNIVERZITET U BEOGRADU - Filozofski fakultet;UNIVERSITY COLLEGE LONDON;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS";"IE;CH;DE;TR;RS;UK;FR";"/LIF;/SCI";1;0;0;1;0;0 93508;238702;FIRST;ONG;FP7-PEOPLE;FP7-PEOPLE-ITN-2008;FP7;Fronts and Interfaces in Science and Technology;2010-01-01;2013-12-31;;Space-time phenomena giving rise to fronts and interfaces are central issues in many contexts of Science and Technology. A selection of some of the most challenging ones, most often of multi-disciplinary character, will be pursued by a team of 10 Full Partner Members (8 universities of different countries and two industries, Guigues Environnement (France) and Siemens (Germany)) with the help of 4 Associate Partners. The project is divided into three general Work Packages A: Image Processing, B: Patterns in Complex Reaction-Diffusion Systems and C: Interfaces, Control and Inverse Methods in Technology Problems. The training of 42 ESR is proposed with a interdisciplinar orientation: besides the presence of the two mentioned industries with special interest in work packages B and C, respectively, most of the mathematicians implied in this ITN in the field of image processing are collaborating with researchers from other fields as in the case of the Technion Computer Sciences and Electrical Engineering departments. The presence of two industrial partners will also broaden the range of applications of the training techniques used in the FIRST. The Guigues and Simens partners, are in the supervisory board of the ITN, and are involved in the training programme through complementary skills seminars. Most of the ESRs will be trained in at least two different universities. The list of structured training courses refers not only to a set of postgraduate courses available in the PhD programmes but to some specialized courses which will be organized for the FIRST ITN. The benefit to the European scientific community will be significant: the training will not only produce researchers with broad backgrounds qualified for academic careers. It will also produce individuals with an understanding of science and with an excellent perspective for a career outside academia.;3974552;3974552;FP7-PEOPLE-ITN-2008;/MC-ITN;UNIVERSIDAD COMPLUTENSE DE MADRID;ES;"UNIVERSITY OF BATH;FRIEDRICH-ALEXANDER-UNIVERSITAET ERLANGEN NUERNBERG;GUIGUES ENVIRONNEMENT SAS;UNIVERSITE PARIS-SUD;UNIVERSITAT ZURICH;TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY;TECHNISCHE UNIVERSITEIT EINDHOVEN;SIEMENS AKTIENGESELLSCHAFT;UNIVERSITA DEGLI STUDI DI ROMA LA SAPIENZA;EGIS STRUCTURES ET ENVIRONNEMENT SA";"UK;DE;FR;CH;IL;NL;IT";"/SCI;/EDU";1;0;0;1;0;0 110412;339116;ANOBEST;ONG;FP7-IDEAS-ERC;ERC-AG-LS1;FP7;Structure function and pharmacology of calcium-activated chloride channels: Anoctamins and Bestrophins;2014-02-01;2020-01-31;;Calcium-activated chloride channels (CaCCs) play key roles in a range of physiological processes such as the control of membrane excitability, photoreception and epithelial secretion. Although the importance of these channels has been recognized for more than 30 years their molecular identity remained obscure. The recent discovery of two protein families encoding for CaCCs, Anoctamins and Bestrophins, was a scientific breakthrough that has provided first insight into two novel ion channel architectures. Within this proposal we aim to determine the first high resolution structures of members of both families and study their functional behavior by an interdisciplinary approach combining biochemistry, X-ray crystallography and electrophysiology. The structural investigation of eukaryotic membrane proteins is extremely challenging and will require us to investigate large numbers of candidates to single out family members with superior biochemical properties. During the last year we have made large progress in this direction. By screening numerous eukaryotic Anoctamins and prokaryotic Bestrophins we have identified well-behaved proteins for both families, which were successfully scaled-up and purified. Additional family members will be identified within the course of the project. For these stable proteins we plan to grow crystals diffracting to high resolution and to proceed with structure determination. With first structural information in hand we will perform detailed functional studies using electrophysiology and complementary biophysical techniques to gain mechanistic insight into ion permeation and gating. As the pharmacology of both families is still in its infancy we will in later stages also engage in the identification and characterization of inhibitors and activators of Anoctamins and Bestrophins to open up a field that may ultimately lead to the discovery of novel therapeutic strategies targeting calcium-activated chloride channels.;2176000;2176000;ERC-2013-ADG;/ERC-AG;UNIVERSITAT ZURICH;CH;;;"/BIO;/LIF";1;0;0;1;0;0 185581;615216;LIFEINVERSE;ONG;FP7-IDEAS-ERC;ERC-CG-2013-PE1;FP7;Variational Methods for Dynamic Inverse Problems in the Life Sciences;2014-03-01;2019-02-28;;"This project will develop novel techniques for solving inverse problems in life sciences, in particular related to dynamic imaging. Major challenges in this area are efficient four- dimensional image reconstruction under low SNR conditions and further the quantification of image series as obtained from molecular imaging or life microscopy techniques. We will tackle both of them in a rather unified framework as inverse problems for time-dependent (systems of) partial differential equations. In the solution of these inverse problems we will investigate novel approaches for the following aspects specific to the above-mentioned problems in the life sciences: 1. Solution of inverse problems for PDEs in complex time-varying geometries 2. Development of appropriate variational regularization models for dynamic images, including noise and motion models 3. Improved forward and inverse modelling of cellular and intracellular dynamics leading to novel inverse problems for nonlinear partial differential equations 4. Construction and implementation of efficient iterative solution methods for the arising 4D inverse problems and their variational formulation All tasks will be driven by concrete applications in biology and medicine and their success will be evaluated in applications to real problems and data. This is based on interdisciplinary work related to electrocardiology and developmental biology. The overall development of methods will however be carried out in a flexible and modular way, so that they become accessible for larger problem classes.";966400;966400;ERC-2013-CoG;/ERC-CG;WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER;DE;;;"/PSE;/MST";1;0;0;1;0;0 102881;291826;M-ERA.NET;ONG;FP7-NMP;NMP.2011.2.3-2;FP7;From materials science and engineering to innovation for Europe;2012-02-01;2016-01-31;https://www.m-era.net/;"M-ERA.NET will be a real tool for developing a strong European RTD community on materials science and engineering and for supporting the European economy with respect to the challenges of the 21st century. M-ERA.NET will be a highly ambitious network involving a majority of European key players in national funding of materials science and engineering. M-ERA.NET will replace a number of smaller previous ERA-NETs and cover the materials domain with an innovative and flexible umbrella concept for one single ERA-NET contract. M-ERA.NET will set up a multi-annual policy for joint programming targeted at the whole innovation cycle. Cooperation at an international level will enable the European RTD community to access world leading knowledge. It is our mission to - strengthen the status of the European RTD community and economy in materials sciences and engineering; - mobilise critical mass of national and regional funding for transnational RTD cooperation in materials science and engineering, thereby achieving a very large leverage effect of the requested FP7 funding; - set up a novel umberlla concept for cooperation to react to emerging needs and to allow coverage of future topics in related thematic areas; - establish strategic programming of joint activities, addressing societal and technological challenges in an interdisciplinary approach; - support the exploitation of created knowledge along the whole innovation chain; - enable enlarged research cooperation within the EU member states and associated states; - establish international cooperation with partners outside Europe; - exploit the novel developments in a durable, long term cooperation between funding organisations.";3490613,42;3000000;FP7-ERANET-2011-RTD;/CSA-CA;OESTERREICHISCHE FORSCHUNGSFOERDERUNGSGESELLSCHAFT MBH;AT;"INSTITUTO DE DESARROLLO ECONOMICO DEL PRINCIPADO DE ASTURIAS;NEDERLANDSE ORGANISATIE VOOR WETENSCHAPPELIJK ONDERZOEK;NEMZETI KUTATASI FEJLESZTESI ES INNOVACIOS HIVATAL;INNOBASQUE AGENCIA VASCA DE LA INNOVACION / INNOBASQUE BERRIKUNTZARENEUSKAL AGENTZIA;FONDS ZUR FÖRDERUNG DER WISSENSCHAFTLICHEN FORSCHUNG;SIHTASUTUS EESTI TEADUSAGENTUUR;RANNSOKNAMIDSTOD ISLANDS;AGENCIA DE INNOVACION Y DESARROLLODE ANDALUCIA;FORSCHUNGSZENTRUM JULICH GMBH;FUNDACION PARA EL CONOCIMIENTO MADRIMASD;IDRYMA PROOTHISIS EREVNAS;Lietuvos mokslo taryba;Unitatea Executiva pentru Finantarea Invatamantului Superior, a Cercetarii, Dezvoltarii si Inovarii;CONSEIL REGIONAL MIDI-PYRENEES;BUNDESMINISTERIUM FUER VERKEHR, INNOVATION UND TECHNOLOGIE;TURKIYE BILIMSEL VE TEKNOLOJIK ARASTIRMA KURUMU;MINISTERO DELL'ISTRUZIONE, DELL'UNIVERSITA' E DELLA RICERCA;DEUTSCHE FORSCHUNGSGEMEINSCHAFT;INNOVAATIORAHOITUSKESKUS BUSINESS FINLAND;LATVIJAS ZINATNU AKADEMIJA;SERVICE PUBLIC DE WALLONIE;BUNDESMINISTERIUM FUER BILDUNG UND FORSCHUNG;ORSZAGOS TUDOMANYOS KUTATASI ALAPPROGRAMOK IRODA;VERKET FÖR INNOVATIONSSYSTEM;AGENTSCHAP VOOR INNOVATIE DOOR WETENSCHAP EN TECHNOLOGIE;MATIMOP, ISRAELI INDUSTRY CENTER FOR RESEARCH & DEVELOPMENT;KARLSRUHER INSTITUT FUER TECHNOLOGIE;NORGES FORSKNINGSRAD;The Technology Strategy Board;VLAAMSE GEWEST;FONDS NATIONAL DE LA RECHERCHE;SLOVENSKA AKADEMIA VIED;MINISTRSTVO ZA VISOKO SOLSTVO, ZNANOST IN TEHNOLOGIJO;REGIONE PIEMONTE;AGENCE NATIONALE DE LA RECHERCHE;Ministrstvo za izobrazevanje, znanost in sport;NARODOWE CENTRUM BADAN I ROZWOJU;FONDS VOOR WETENSCHAPPELIJK ONDERZOEK-VLAANDEREN;FUNDACAO PARA A CIENCIA E A TECNOLOGIA";"ES;NL;HU;AT;EE;IS;DE;CY;LT;RO;FR;TR;IT;FI;LV;BE;SE;IL;NO;UK;LU;SK;SI;PL;PT";/MAT;1;0;0;1;0;0 97543;264666;CCQED;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-ITN;FP7;Circuit and Cavity Quantum Electrodynamics;2011-01-01;2014-12-31;;"This network will bridge two very active disciplines in physics, namely the quantum electrodynamics of atoms or ions strongly interacting with light in resonators, and the emerging field of solid-state superconducting circuit quantum electrodynamics. Advanced techniques will be developed jointly with industry partners for the manipulation of a deterministic number of particles - atoms, ions or artificial atoms - with electromagnetic fields covering the microwave and the optical frequency spectrum. The interdisciplinary training of a new generation of young researchers will strengthen the European expertise in those fields, and will allow for a new discipline to emerge that combines single-atom control methods with superconductor micro-chip fabrication. The use of high-quality resonators, whether superconducting transmission lines or highly-reflecting mirrors, coupled to a controlled number of particles will open novel avenues to explore quantum dynamics via hitherto inaccessible physical mechanisms. These new control scenarii will be strengthened by the development of potentially marketable technologies of great multidisciplinary interest. The network groups 10 research centres and 3 companies representing the cutting edge of research in the quantum electrodynamics of fundamental systems in Europe. The network will train 12 ESRs and 2 ERs, with focus on (i) establishing bonds between solid-state and quantum optics physics, (ii) strengthening the communication between theory and experiment, and, (iii) concretizing links between fundamental and applied research. Prominent scientists and industry leaders will contribute to the schools and workshops. Special attention will be given on developing complementary skills, such as communication, presentation, project planning and management.";3513617,44;3513617,44;FP7-PEOPLE-2010-ITN;/MC-ITN;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;DE;"AARHUS UNIVERSITET;COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES;NATIONAL INSTRUMENTS GERMANY GMBH;Menlo Systems GmbH;BAYERISCHE AKADEMIE DER WISSENSCHAFTEN;RHEINISCHE FRIEDRICH-WILHELMS-UNIVERSITAT BONN;EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH;MAGYAR TUDOMANYOS AKADEMIA WIGNER FIZIKAI KUTATOKOZPONT;SZILARDTESTFIZIKAI ES OPTIKAI KUTATOINTEZETE - MAGYAR TUDOMANYOS AKADEMIA;UNIVERSITAET INNSBRUCK;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA";"DK;FR;DE;CH;HU;AT;ES";"/EDU;/NET";1;0;0;1;0;0 92454;238017;HARVEST;ONG;FP7-PEOPLE;FP7-PEOPLE-ITN-2008;FP7;Control of Light Use Efficiency in Plants and Algae - From Light to Harvest;2009-10-01;2013-09-30;;Photoprotection against excess absorbed light energy is an essential and universal attribute of oxygenic photosynthetic organisms. This requirement has been a strong force in the evolution of plants and micro-organisms, and a diverse range of solutions have arisen. It has determined survival, productivity and habitat preference, and it determines the ceiling on the efficiency of energy conversion in photosynthesis in natural environment. Its investigation also provides insights into unique nanoscale switching processes. Understanding the molecular mechanisms of biological light adaptation will therefore have implication for many aspects of life, such as agriculture and food security, biodiversity and global climate change, biosolar energy and biofuels. This network brings together major high-quality EU centres with expertise in a wide range of disciplines – from plant physiology to molecular biology, structural biology and photophysics – and with great interest in interdisciplinary collaborative research. The network will thus provide a unique training opportunity for young researchers in key aspects of molecular biosciences and biophysical sciences in the context of practical applications in instrument development, agronomy, ecology and biotechnology. Researchers from within and outside this network will receive key research skills from several disciplines combined in a high-level and intrinsically collaborative research project, key transferable skills on information technology, written and oral communication and critical assessment, and key business and commercial skills on commercial exploitation and product development.;4683560;4683560;FP7-PEOPLE-ITN-2008;/MC-ITN;STICHTING VU;NL;"UNIVERSITA DEGLI STUDI DI VERONA;THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;MAGYAR TUDOMANYOS AKADEMIA SZEGEDIBIOLOGIAI KUTATOKOZPONT;VERENIGING VOOR CHRISTELIJK HOGER ONDERWIJS WETENSCHAPPELIJK ONDERZOEK EN PATIENTENZORG;UMEA UNIVERSITET;JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN;PHOTON SYSTEMS INSTRUMENTS SPOL SRO;Plant Dynamics BV;WAGENINGEN UNIVERSITY;RIJKSUNIVERSITEIT GRONINGEN;QUEEN MARY UNIVERSITY OF LONDON;TURUN YLIOPISTO";"IT;UK;FR;DE;HU;NL;SE;CZ;FI";"/SCI;/EDU";1;0;0;1;0;0 104156;295673;EMOBODIES;ONG;FP7-IDEAS-ERC;ERC-AG-SH4;FP7;Bodies express emotions and actions in sociocultural context;2012-07-01;2018-03-31;;Emotions are adaptive actions that take place in the real world and involve the whole body. In contrast with an overwhelming number of studies on facial expressions, very little research has been devoted to how emotions are expressed by the whole body and its actions in the real world. This proposal combines neuropsychology and emotion research with normal and unique patient populations. It will apply innovative combinations of physiological and multimodal imaging methods (EEG/MEG and fMRI, EMG and TMS) and novel technologies like IVR and contribute to adapting immersive virtual reality tools for research and application. The proposal is highly interdisciplinary linking different methodological approaches and combining basic with application-oriented research. Novel findings on how the whole body expresses and communicates emotion and action are of major scientific interest and have direct societal, clinical, information technological and practical payoffs. The results will contribute a novel and far reaching understanding of nonverbal communication, of gender –related and cultural differences, and of affective communication deficits. Applications also include a novel body communication test and we will provide to the community at large a set of stimuli for measuring bodily expressions in action.;2499541;2499541;ERC-2011-ADG_20110406;/ERC-AG;UNIVERSITEIT MAASTRICHT;NL;UNIVERSITY COLLEGE LONDON;UK;/MED;1;0;0;1;0;0 90214;223744;DOPAMINET;ONG;FP7-HEALTH;HEALTH-2007-2.1.2-5;FP7;Molecular Networks of Dopaminergic Neurons in Chordates;2009-02-01;2012-07-31;http://www.dopaminet.eu/;Background. Parkinson Disease is the second most common progressive neurodegenerative disorder. The selective degeneration of subsets of midbrain dopaminergic neurons is believed to be the primary cause for disruption of the ability to control movements. Objective. We propose to apply a highly interdisciplinary approach to construct complex networks consisting of protein coding genes, non-protein-coding genes and cis-regulatory elements within dopaminergic neurons in the brain across three chordate organisms (Mouse, Zebrafish and Ciona) to identify and compare gene regulatory networks in these neurons. This will be achieved by: • Expression profiling of genes on single dopaminergic neurons via laser microdissection and transgenic lines in Mouse, Ciona and Zebrafish • HT-Sequencing of microCAGE assays on dopaminergic neurons, providing TSS usage and transcript discovery • Microscopy HTS of cis-regulatory elements • siRNA and morpholino network perturbation experiments • Innovative systems biology approaches to decipher and define molecular networks Data generated by microCAGE and microarray will define a set of key genes in dopaminergic neurons, in which cis-regulatory elements will be predicted and screened utilizing HTS in zebrafish. The data will aid network reconstruction, which will be validated by perturbation experiments. This project relies also on the availability of data produced through the many existing collaborations among consortium partners such as FP6 funded TRANSCODE project as well as the international Fantom3 consortium. Potential impact: The prevalence of PD in Europe today is ~2 million people. Within the next 50 years, the number is expected to rise to 5 million. Thus, the burden placed by dementia on the working-age population will rise dramatically. No treatments are known to slow the progression of the disease. Deciphering the basic networks of dopaminergic neurons will generate novel diagnostic and therapeutic candidates.;3831030;2967180;FP7-HEALTH-2007-B;/CP-FP;SCUOLA INTERNAZIONALE SUPERIORE DI STUDI AVANZATI DI TRIESTE;IT;"YH YOUHEALTH AB;RIKEN THE INSTITUTE OF PHYSICAL AND CHEMICAL RESEARCH;ALBERT-LUDWIGS-UNIVERSITAET FREIBURG;THE UNIVERSITY OF BIRMINGHAM;KARLSRUHER INSTITUT FUER TECHNOLOGIE;CLINICAL GENE NETWORKS AB;UNIVERSITY COLLEGE LONDON;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;CONSORZIO PER IL CENTRO DI BIOMEDICINA MOLECOLARE SCARL";"SE;JP;DE;UK;FR;IT";"/BIO;/SCI;/MED";1;0;0;1;0;0 97041;264508;TREATPOLYQ;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-ITN;FP7;TreatPolyQ – Industrial Academic Initial Training Network towards treatment of Polyglutamine Diseases;2011-03-01;2015-02-28;http://www.treatpolyq.eu/;Protein aggregation is a hallmark of many late onset neurodegenerative disorders including Parkinson’s Disease (PD), Alzheimer’s Disease (AD), amyotrophic lateral sclerosis (ALS), prion diseases as well as the group of polyglutamine diseases (polyQ). The aim of this proposal is to create a network of European partners bridging important basic mechanisms involved in proteinopathies, research of model diseases and treatment approaches. The “TreatPolyQ” network will focus on two main representatives of the polyQ diseases: Huntington’s disease as the most common polyQ disease as well as spinocerebellar ataxia type 3 (SCA3) as the most frequent autosomal-dominantly inherited ataxia. Patients suffer from a multitude of neurological symptoms including movement abnormalities with late onset and in a progressive manner. Up to now, no treatment or cure is available. The network will be consisting of a rare combination of experts from basic and translational research, including a Nobel prize laureate, four industrial partners (two medium, and two small companies, all incorporated as full participants) and academic leaders of the field. The network not only focuses on one special aspect of a disease but spans several important disease-associated mechanism as well as promising treatment strategies for HD and SCA3 (protein transport, protein folding, protein degradation via both the ubiquitin-proteasome system and autophagy), likely to be important across a range of neurodegenerative diseases. In order to implement these research projects, extensive collaborations and temporarily personnel secondments of the involved researchers will take place, enhancing interdisciplinary transfer of knowledge. Beyond the personalized local training plan for each employed researcher within the Network, there will be 4 structured courses covering aspects ranging from structural biology to protein degradation to model organisms and drug development, including soft skill training.;3757318;3757318;FP7-PEOPLE-2010-ITN;/MC-ITN;EBERHARD KARLS UNIVERSITAET TUEBINGEN;DE;"SIENA BIOTECH SPA;THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;UNIVERSITE PARIS DIDEROT - PARIS 7;NSGENE AS;AC Immune SA;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;ENKAM PHARMACEUTICALS A/S;CENTRO DE NEUROCIENCIAS E BIOLOGIACELULAR ASSOCIACAO;INSTITUT CURIE;H. LUNDBECK AS;KAROLINSKA INSTITUTET;TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY;LUNDS UNIVERSITET;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;KING'S COLLEGE LONDON";"IT;UK;FR;DK;CH;DE;PT;SE;IL";"/EDU;/NET";1;0;0;1;0;0 99677;282510;BLUEPRINT;ONG;FP7-HEALTH;HEALTH.2011.2.1.1-1;FP7;A BLUEPRINT of Haematopoietic Epigenomes;2011-10-01;2016-09-30;http://www.blueprint-epigenome.eu/;In response to the call for a high impact initiative on the human epigenome, the BLUEPRINT Consortium has been formed with the aim of generating at least 100 reference epigenomes and studying them to advance and exploit knowledge of the underlying biological processes and mechanisms in health and disease. BLUEPRINT will focus on distinct types of haematopoietic cells from healthy individuals and on their malignant leukaemic counterparts. Reference epigenomes will be generated by state-of-the-art technologies from highly purified cells for a comprehensive set of epigenetic marks in accordance with quality standards set by IHEC. This resource-generating activity will be conducted at dedicated centres to be complemented by confederated hypothesis-driven research into blood-based diseases, including common leukaemias and autoimmune disease (T1D), by epigenetic targets and compound identification, and by discovery and validation of epigenetic markers for diagnostic use. By focussing on 100 samples of known genetic variation BLUEPRINT will complete an epigenome-wide association study, maximizing the biomedical relevance of the reference epigenomes. Key to the success of BLUEPRINT will be the integration with other data sources (i.e. ICGC, 1000 genomes and ENCODE), comprehensive bioinformatic analysis, and user-friendly dissemination to the wider scientific community. The involvement of innovative companies will energize epigenomic research in the private sector by creating new targets for compounds and the development of smart technologies for better diagnostic tests. BLUEPRINT will outreach through a network of associated members and form critical alliances with leading networks in genomics and epigenomics within Europe and worldwide. Through its interdisciplinarity and scientific excellence combined with its strong commitment to networking, training and communication BLUEPRINT strives to become the cornerstone of the EU contribution to IHEC.;39664716,88;29996664;FP7-HEALTH-2011-single-stage;/CP-IP;STICHTING KATHOLIEKE UNIVERSITEIT;NL;"CELLZOME GMBH;FUNDACION CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III;SIENA BIOTECH SPA;Novartis Forschungsstiftung;THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;ISTITUTO EUROPEO DI ONCOLOGIA SRL;INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE;AGILENT TECHNOLOGIES SWEDEN AB;UNIVERSITE DE GENEVE;OXFORD NANOPORE TECHNOLOGIES LTD;GENOME RESEARCH LIMITED;WEIZMANN INSTITUTE OF SCIENCE;EUROPEAN MOLECULAR BIOLOGY LABORATORY;FUNDACIO PARC CIENTIFIC DE BARCELONA;UNIVERSITAET ULM;FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION;DIAGENODE;VIVIA BIOTECH S.L.;EURICE EUROPEAN RESEARCH AND PROJECT OFFICE GMBH;ACADEMISCH ZIEKENHUIS GRONINGEN;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;KOBENHAVNS UNIVERSITET;CHRISTIAN-ALBRECHTS-UNIVERSITAET ZU KIEL;UNIVERSITAET LEIPZIG;CELLZOME AG;THE BABRAHAM INSTITUTE;CONSORCI INSTITUT D'INVESTIGACIONS BIOMEDIQUES AUGUST PI I SUNYER;UNIVERSITAETSKLINIKUM ESSEN;CEMM - FORSCHUNGSZENTRUM FUER MOLEKULARE MEDIZIN GMBH;Genomatix Software GmbH;SIGOLIS AB;UNIVERSITA DEGLI STUDI DELLA CAMPANIA LUIGI VANVITELLI;ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM;LUNDS UNIVERSITET;UNIVERSITY COLLEGE LONDON;QUEEN MARY UNIVERSITY OF LONDON;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FUNDACIO INSTITUT D'INVESTIGACIO BIOMEDICA DE BELLVITGE;FUNDACIO CENTRE DE REGULACIO GENOMICA;THE UNIVERSITY OF EDINBURGH;UNIVERSITA DEGLI STUDI DI ROMA LA SAPIENZA;HALO GENOMICS AB;BARCELONA SUPERCOMPUTING CENTER - CENTRO NACIONAL DE SUPERCOMPUTACION;UNIVERSITAT DES SAARLANDES";"DE;ES;IT;CH;UK;FR;SE;IL;BE;NL;DK;AT";/MED;1;0;0;1;0;0 92183;236110;GPCRS;ONG;FP7-PEOPLE;FP7-PEOPLE-IEF-2008;FP7;Conversion of integral membrane receptors into soluble forms;2009-09-01;2011-08-31;;G-protein coupled receptors (GPCRs) are cell surface receptors that mediate the cellular responses to an enormous diversity of endogenous signaling molecules as well as environmental signals. GPCRs are a major target for the pharmaceutical industry as is reflected by the fact that more than 50% of all medicines available today act on a GPCR and represent about a quarter of the top-selling drugs worldwide. However, effective drug design and functional characterization of these receptors is strongly limited by the absence of high-resolution structural information because of the many practical problems of working with membrane proteins. Here, we propose to replace the lipid-exposed hydrophobic residues within the transmembrane domains of GPCRs with more hydrophilic residues to engineer water-soluble variants of GPCRs capable of folding in aqueous solutions. Moreover, detailed comparison of membrane proteins and soluble proteins by protein engineering will also lead to a deeper insight into membrane protein folding and stability with important consequences for the handling of drug targets. Redesigning a GPCR by substituting the hydrophobic amino acids of the protein/lipid interface with suitable polar or charged residues to produce a molecule that is able to fold and function in aqueous solution represents an ambitious protein-engineering problem of high combinatorial complexity. It is improbable that we will reach the desired result in a single step by rational design. Instead, we have chosen a highly interdisciplinary approach that combines the strengths of computational and experimental tools, of design, selection and in vitro evolution. The strategy, we propose to use, relies on the proven expertise of the Plückthun group in the rational design of protein libraries. From these libraries, functional molecules can efficiently be selected by ribosome display methods. Selected sequences can be further optimized using the techniques of directed in vitro evolution.;;263599,24;FP7-PEOPLE-IEF-2008;/MC-IEF;UNIVERSITAT ZURICH;CH;;;"/SCI;/EMP";1;0;0;1;0;0 106542;309846;PCATDES;ONG;FP7-NMP;NMP.2012.2.2-6;FP7;Photocatalytic Materials for the Destruction of Recalcitrant Organic Industrial Waste;2013-02-01;2017-01-31;http://www.pcatdes.eu/;The project brings together a consortium of EU and ASEAN researchers with the aim of developing a solar powered photocatalytic waste-water treatment system capable of mineralising the recalcitrant organic matter that is not removed by current biological methods. With an emphasis on generating novel materials and new understandings of photocatalytic materials and processes, the interdisciplinary team aims to develop cost effective prototype photocatalytic reactors capable of deployment in remote areas and of treating contaminated water from small scale industrial producers at rates of up to 500 m3 of a day.;5148336,61;3954395;FP7-NMP-2012-SMALL-6;/CP-SICA;CARDIFF UNIVERSITY;UK;"UNIVERSITY OF BATH;NATIONAL SCIENCE & TECHNOLOGY DEVELOPMENT AGENCY;UNIVERSIDAD REY JUAN CARLOS;UNIVERSITAET ROSTOCK;UNIVERSITY COLLEGE LONDON;SIRIM BERHAD;VIEN KHOA HOC VAT LIEU;VIEN CONG NGHE HOA HOC - VIEN KHOA HOC VA CONG NGHE VIETNAM;SAMPAS NANOTEKNOLOJI ARASTIRMA GELISTIRME VE PAZARLAMA LIMITED SIRKETI;ASTON UNIVERSITY";"UK;TH;ES;DE;MY;VN;TR";/SCI;1;0;0;1;0;0 109829;607962;NEUROINFLAMMATION;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-ITN;FP7;nEUROinflammation;2013-10-01;2017-09-30;;Neuroinflammation is a hallmark of multiple sclerosis and ischemic stroke. Investigating neuroinflammation as a common theme in neurological disorders, this ITN will focus in particular on myeloid cells, microglia, and endothelial cells. Sixteen partners from the academic and private sector with complementary scientific background join forces to train 13 ESRs in neuroinflammatory concepts and technologies that are valid across specific disease entities. Using an interdisciplinary and intersectorial approach the training will promote technical expertise, insight into entrepreneurship, as well as leadership and communication skills and lay the foundation for a successful career of ESRs either in the academic or private sector.;3446289,88;3446289,88;FP7-PEOPLE-2013-ITN;/MC-ITN;UNIVERSITAT ZU LUBECK;DE;"STICHTING VU;UNIVERSITAET BERN;MEDEIA THERAPEUTHICS OY;AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS;STICHTING VUMC;UNIVERSITE DE CAEN NORMANDIE;INSTYTUT BIOLOGII DOSWIADCZALNEJ IM. M. NENCKIEGO POLSKIEJ AKADEMII NAUK;Chiesi Farmaceutici S.p.A;WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER;UNIVERSITAETSKLINIKUM FREIBURG;ITA-SUOMEN YLIOPISTO;EUROIMMUN MEDIZINISCHE LABORDIAGNOSTIKA AG;UNIVERSITA DEGLI STUDI DI BRESCIA";"NL;CH;FI;ES;FR;PL;IT;DE";/LIF;1;0;0;1;0;0 109878;607896;ORGBIO;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-ITN;FP7;Organic Bioelectronics;2013-10-01;2017-09-30;http://orgbio.eu/;"Organic Bioelectonics is a new discipline which holds promise to shape, direct, and change future medical treatments in a revolutionary manner over the next decades. At the moment Europe has a unique leading position in this area, being almost all the world-leading groups in this field located in Europe and constituting the core of this international training network. However, realizing the promise of “Organic bioelectronics” requires research and training not only crossing disciplines, such as electrical engineering, biology, chemistry, physics, and materials science, but also crossing our European countries. “The EU will add value on the global scene only if it acts jointly”. OrgBIO is at the core of European technological innovation and will become an indispensable part of the educational canon. It will establish a world-class training platform spreading around the highly interdisciplinary / intersectorial European-led area of organic bioelectronics. Education along with science and entrepreneurial mindsets and attitudes is the core of the OrgBIO training programme, which aims at excellence and innovation, at all level. Excellence in science is guaranteed by the world-leading groups which founded this research area. Innovation in education is guaranteed by the involvement of researchers on education, business experts. Using different sensors, actuators, electronic and interconnect technologies the network will develop multifunctional systems based on organic devices and materials with high sensitivity that are also flexible, conformable and present over large areas for various biomedical / biological applications in the life science. Multi-analyte and disposable analytical systems manufactured by large-area printing methods will provide services to the individuals and healthcare community. Targeted implemented interactions with a wide network of venture capitals and business actors will immediately transfer the research outcome to the European Industry.";3784176,88;3784176,88;FP7-PEOPLE-2013-ITN;/MC-ITN;INSTITUT MINES-TELECOM;FR;"LINKOPINGS UNIVERSITET;IBIDI GMBH;IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE;DUBLIN CITY UNIVERSITY;HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH;TECHNISCHE UNIVERSITAET MUENCHEN;NANION TECHNOLOGIES GMBH;PLASMA SOLUTION SRL;UNIVERSITA DEGLI STUDI DI BARI ALDO MORO;STMICROELECTRONICS SRL;ECOLE NATIONALE SUPERIEURE DES MINES DE SAINT-ETIENNE;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA;SVEUCILISTE U RIJECI";"SE;DE;UK;IE;IT;FR;ES;HR";/LIF;1;0;0;1;0;0 109611;607817;INTERAQCT;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-ITN;FP7;International Network for the Training of Early stage Researchers on Advanced Quality control by Computed Tomography;2013-10-01;2017-09-30;https://www.interaqct.eu/;"'The non-destructive quality control of a wide variety of high-added value products, produced by innovative manufacturing techniques, remains a challenge. Examples include additive manufacturing parts, micro parts, and fibre reinforced composite parts. Common to these workpieces is the dependency of their performance on internal and inaccessible elements. Nevertheless, customers in multiple sectors are requesting certified quality and reliability. For the last few years industrial Computed Tomography (CT) has been regarded as a promising technology, which can evolve towards integrated quality control of complex workpieces combining dimensional metrology and material defect analysis. However, major challenges remain in order to exploit its full potential. Meeting these requires a broad range of expertise, including physics, dimensional metrology, non-destructive testing, material sciences, precision engineering, and manufacturing engineering. Due to the distinct interdisciplinary character, there is a strong need for young researchers with a broad range of competences to achieve the envisaged innovation breakthrough in the EU industry. The INTERAQCT project has been conceived as a pan-European industrial-academic initiative that will provide the unique and encompassing training environment required, by bringing together expertise from industry and academia in each of these domains (CT-equipment, CT-software, NDT, dimensional metrology, additive manufacturing, micro-manufacturing, composite manufacturing). The research will develop procedures for fast and accurate CT model acquisition, with special emphasis on multi-material parts. Furthermore, INTERAQCT targets quantification and improvement of the reliability of CT measurement results, by determining the probability of detection of material defects as well as by achieving metrological traceability. In addition, CT based quality improvement loops will be targeted for key emerging manufacturing technologies.'";3850553,52;3850553,52;FP7-PEOPLE-2013-ITN;/MC-ITN;KATHOLIEKE UNIVERSITEIT LEUVEN;BE;"MATERIALISE NV;NPL MANAGEMENT LIMITED;VOLUME GRAPHICS GMBH;FH OO FORSCHUNGS & ENTWICKLUNGS GMBH;PHYSIKALISCH-TECHNISCHE BUNDESANSTALT;RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN;FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.;UNIVERSITA DEGLI STUDI DI PADOVA;X-TEK SYSTEMS LTD;DANMARKS TEKNISKE UNIVERSITET";"BE;UK;DE;AT;IT;DK";/LIF;1;0;0;1;0;0 104191;286334;PSYCH-AID;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IAPP;FP7;Advanced Immuno-neuro-endocrine Diagnostics in Psychiatry;2012-06-01;2016-05-31;;"'The current diagnosis of psychiatric disorders such as schizophrenia and mood disorders, is highly subjective, due to the lack of empirical markers or objective tests specific for these diseases. PSYCH-AID searchers to fill the gap thrpugh the in-parallel study of schizophrenia and mood disorder patients combining, validating and registering 4 sets of biomarker tests already in advanced stage of development in two other EU-FP7 projects of partners (MOODINFLAME and SchizDX). Biomarkers are based on activated immune response system in conjunction with an abnormal neuro-endocrine set point. PSYCH-AID aims at the developm,ent of clinically applicable blood assays identifying pateints/individuals with such activated set points by combining the efforts of academia and industry. PSYCH-AID unites 9 European partners excelling in this field: 5 academia and 5 SMEs. The intersectoral and interdisciplinary collaboration and exchange of researchers will foster the translation of fundamental clinical research into practical solutions for the diagnosis and treatment of people affected by schizophrenia or mood disorders. This fit perfectly with the IAPP scheme. PSYCH-AID contributes to building a long lasting collaboration between the partners, the first consortium in the world to put objective diagnostic and prognostic tests for psychiatric disorders into practice. European industry will benefit from this competitive lead. Since the disorders have a serious impact on the quality of life of the individuals affected, an improved diagnosis and prognosis will substantially contribute to improving their quality of life. Furthermore, PSYCH-AID gives the researchers involved a platform to acquire complementary skills, thus ameliorating their professional career opportunities.'";3649514;3649514;FP7-PEOPLE-2011-IAPP;/MC-IAPP;ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM;NL;"GENEURO INNOVATION SAS;EDI Experimentelle Diagnostische Immunologie GmbH;PSYNOVA NEUROTECH LTD;LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN;ACADEMISCH ZIEKENHUIS GRONINGEN;RADIOLOGY MORPHOLOGICAL SOLUTIONS BV;Foundation Biological Psychiatry;ADVANCED PRACTICAL DIAGNOSTICS;WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER;CROSSLINKS BV";"FR;DE;UK;NL;BG;BE";/IND;1;0;0;1;0;0 100523;269186;KRAB-ZNF;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-IRSES;FP7;KRAB zinc finger gene biology in evolution and disease;2011-07-01;2015-06-30;;The „KRAB-ZNF“ initiative is driven by recent observations that KRAB-ZNF genes, an evolutionarily conserved gene family of more than 350 transcriptional repressors encoded in the human genome, are predominantly expressed in testis and fetal brain. To elucidate functions of KRAB ZNF genes in evolution and diseases, experts in KRAB ZNF gene biology (B1/P1), proteomics (B1/P2), systems biology and aging (B2/P3), interspecies brain life histories (B3/P4), primate socioecology (B3/P5), human pathology (B3/P6) and in any aspect of computational biology (B4/P7-B6/P11) have established a well-coordinated interdisciplinary exchange program between German (B1,B2/P1-P3), Swiss (B3,P4-P6) and Chinese (B4/P7-B6/P11) institutions. Bioinformatic expertise encompasses network analysis (B4/P7 and B6/P10), molecular structure modeling (B5/P9), database design (B4/P8), and deep sequencing bioinformatics (B6/P11). Workpackages with defined topics are focused on the toponome analysis of KRAB ZNF protein expression (WP1), studying KRAB-ZNF interactions with TRIM28 (WP2), relating KRAB-ZNF gene functions to longevity (WP3), comparing brain sizes, fertility, cognitive behaviours and other aspects of life histories from birds to mammals (WP4), correlating SNPs of brain-related genes with social behaviour of e.g. primates (WP5), and on studying KRAB ZNF protein and related target proteins thereof in human pathology (WP6). The experimental data (B1/P1-B3/P6) will be analyzed in conjunction with experts in bioinformatics (B4/P7-B6/P11), compared to existing world-wide-knowledge (WP7), upon perturbation by small molecules (WP8), modeled upon protein interaction data (WP9), assembled in comprehensive databases (WP10), and finally analyzed phylogenomically (WP11). Within the requested funding period of 48 months, the “KRAB-ZNF” initiative is expected to achieve major contributions in elucidating KRAB ZNF gene functions in primate evolution, ontogenesis, neural development, longevity and disease.;243600;243600;FP7-PEOPLE-2010-IRSES;/MC-IRSES;UNIVERSITAET ROSTOCK;DE;"UNIVERSITAETSKLINIKUM BONN;UNIVERSITAT ZURICH;LEIBNIZ-INSTITUT FUR NATURSTOFF-FORSCHUNG UND INFEKTIONSBIOLOGIE EV HANS-KNOLL-ISTITUT";"DE;CH";"/EMP;/SOC";1;0;0;1;0;0 111068;339105;MORPHOGEN;ONG;FP7-IDEAS-ERC;ERC-AG-LS3;FP7;Morphogenetic growth control by time derivatives of signaling;2014-05-01;2019-04-30;;"How do na?ve cells in a developing tissue know when to divide and when to stop dividing when the tissue reaches its final size? How do they acquire information about their position to generate morphological patterns? Morphogen gradients have been shown to control pattern formation and growth. While the mechanisms of patterning are starting to be understood, the mechanism of growth by morphogens is not yet deciphered. In a few recent reports, we studied the biophysics and cell biology of the Dpp morphogen gradient during growth of Drosophila imaginal discs. We showed that the Dpp gradient expands and scales with the size of the growing tissue. Scaling occurs by the regulation of Dpp lysosomal degradation as a function of tissue size. We also showed that any cell in the developing tissue (no matter the developmental stage, the position of the cell in the gradient or the imaginal disc considered) divides when it sees an increase of Dpp signaling by ?=50% from the beginning of the cell cycle. The proliferation rate g of cells is proportional to the relative time derivative of signaling (i.e. C ?/C, the time derivative of Dpp signaling level C ? (Cdot) normalized to the actual signaling level C): g=(ln2/?)*(Cdot/C). We will study the molecular cell-biology of growth control by morphogens in an interdisciplinary combination of physical theory, biophysics and biochemistry in the context of development.";2499509;2499509;ERC-2013-ADG;/ERC-AG;UNIVERSITE DE GENEVE;CH;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;DE;"/BIO;/LIF";1;0;0;1;0;0 90120;220387;PROMET;ONG;FP7-PEOPLE;PEOPLE-2007-2-1.IEF;FP7;PP2C phosphatases as regulators in development and stress-pathways: Identification of protein complexes and molecular pathways by (phospho)proteomics/metabolomics;2009-03-01;2011-02-28;;Protein phosphorylation has been recognized as one of the most versatile mechanisms that underpin several critical adaptive and developmental processes in plants serving as fast and accurate process to message signals within the cells to generate nuclear responses. Advances in functional dissection of canonical signalling pathways demonstrate that protein phosphatases and their substrate kinases are key determinants in developmental decisions and plant stress tolerance. Plant protein phosphatases of PP2C-type are essential components opening new approaches for deciphering the very early events in cell signalling. This project, aided by the combinations of multidisciplinary cutting-edge technologies, such as proteomics, phosphoproteomics, bioinformatics, molecular biology and metabolomics, is expected to precisely identify the protein associations assembled upon stress conditions and developmental processes through PP2Cs in the model plant Arabidopsis. Research and training in highly developed technologies are expected to stimulate European competitiveness in resolution of cell signalling mechanisms by proteomic tools, uncover the links to metabolic pathways and reinforce further innovations with significant scientific impacts. “ProMet” is introducing EU priority research directions and topics, providing the advanced excellence in molecular biology, proteomics and metabolomics to carry out interdisciplinary technical developments important not only for plants but for life sciences in general. Uncovering the functions and targets of signalling components phosphatases that control key developmental and stress signalling pathways is an essential task that finally affects the environmental issues, future innovations and socio-economic impacts.;166982,27;166982,27;FP7-PEOPLE-2007-2-1-IEF;/MC-IEF;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;DE;;;"/SCI;/EDU";1;0;0;1;0;0 87289;211252;INSTRUCT;ONG;FP7-INFRASTRUCTURES;INFRA-2007-2.2-01;FP7;Integrated Structural Biology Infrastructure;2008-04-01;2011-03-31;;"Structural biology in the next two decades aims to integrate structural knowledge at different resolution levels into specific cellular contexts, with a temporal component, to underpin biomedical sciences. This challenge requires the seamless integration of techniques providing information in different resolution ranges. INSTRUCT will link the information obtained by the major structural biology methods with state-of-the art cell biology techniques to provide a dynamic picture of key cellular processes at all scales. Major technology advances, from high throughput methods in protein production, though NMR and X-ray crystallography to electron microscopy mean that major investment in infrastructure is required to maintain European competitiveness. The preparatory phase of INSTRUCT will forge a pan-European structure comprising a number of Core Centres, with broad infrastructure provision, an appropriate number of Associate Centres, with complimentary expertise and establish the mechanisms for establishing National Access Holder Communities of users and rules for access. The development of cutting-edge infrastructure will be energised by a focus on a few key biomedical questions and environment problems. There will be strong involvement of European industry and SMEs, by both direct collaboration on feasibility studies and by consultation; this will arise naturally as the requirements for high precision innovative instrumentation will challenge European industry to improve their capabilities and the use of the facilities for industrial research will strengthen Europe’s industrial competitiveness in particular in bio-pharma companies. The project will include a training program based on relevant interdisciplinary expertise. A major aim of the preparatory phase will be to establish the mechanisms, financial and legal, by which major funding bodies can work together to provide a coherent European infrastructure with wide European access.";7543170,8;4499988;FP7-INFRASTRUCTURES-2007-1;/CP-CSA-Infra;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;UK;"WEIZMANN INSTITUTE OF SCIENCE;EUROPEAN MOLECULAR BIOLOGY LABORATORY;COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;BUNDESMINISTERIUM FUER BILDUNG UND FORSCHUNG;CONSORZIO INTERUNIVERSITARIO RISONANZE MAGNETICHE DI METALLO PROTEINE;UNIVERSITY OF YORK;BRUKER BIOSPIN GMBH;THE ISRAELI MINISTRY OF SCIENCE, CULTURE AND SPORT;CENTRE EUROPEEN DE RECHERCHE EN BIOLOGIE ET MEDECINE;CONSIGLIO NAZIONALE DELLE RICERCHE;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;MEDICAL RESEARCH COUNCIL";"IL;DE;FR;IT;UK";/SCI;1;0;0;1;0;0 101171;293741;ERAS;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-CIG;FP7;Enhanced Research Activities in Stratigraphy;2011-11-01;2017-08-20;;Robust stratigraphic correlations are essential in deciphering Earth History, yet there are crucial gaps and limitations in the current status of Cenozoic planktonic foraminiferal biochronology. Previous records are hampered by low resolution analysis, incomplete cores and/or lack of magnetostratigraphic age control. As such there is a critical need for high resolution biochronology to improve the accuracy of existing age calibrations. The applicant is in an ideal position to address these issues and contribute substantially to the development of the Cenozoic integrated time scale. Though “Enhanced Research Activities in Stratigraphy (ERAS)” I propose to significantly advance Cenozoic biochronology by producing detailed calibrations of planktonic foraminiferal bioevents. The proposed project is original and innovative, with finer scale stratigraphic analysis than any previous research in this field. The investigation utilizes new deep sea cores in the Pacific Ocean with expanded and complete sedimentary successions and well defined magneto- and cyclo-stratigraphies, which allow direct and accurate calibration of planktonic foraminiferal bioevents to the Geomagnetic Polarity Time Scale and Astronomical Time Scale. The proposed research is the cutting edge in Cenozoic biochronology and will set new standards by pushing forward the temporal resolution of biostratigraphic studies. The expected results will contribute to EU excellence by significantly advancing the understanding of the chronology of biotic evolution during the Cenozoic and will actively contribute to the EARTHTIME-EU Research Network Programme. It is envisaged that the Marie Curie Career Integration Grant will facilitate the reintegration of the researcher into the European research area by enabling interdisciplinary collaborations between the applicant and renowned researchers in other EU Member States.;100000;100000;FP7-PEOPLE-2011-CIG;/MC-CIG;UNIVERSITY COLLEGE LONDON;UK;UNIVERSITY OF LEEDS;UK;/SCI;1;0;0;1;0;0 111069;339129;LIPIDARRAY;ONG;FP7-IDEAS-ERC;ERC-AG-LS4;FP7;Development and application of global lipidomic arrays to inflammatory vascular disease;2014-02-01;2019-01-31;;"How lipids are regulated on a global scale during vascular inflammation is not known. Thus, a major challenge exists to describe and catalog the total lipidome, in particular enabling the identification of new biologically active lipids, and description of changes. This is analogous to ‘omics’ of DNA, RNA and protein, but instead describing diversity of lipids in tissue samples. Importantly, this would encompass not only knowns, but also the vast number of unknowns that have not yet been catalogued in any study so far. Here, new systems biology approaches that can be applied to many other diseases or samples, and integrated with transcriptomic or proteomic analyses will be developed. These would be used to characterize the global lipidome during differentiation of immune cells, and in ex vivo samples from genomically-characterized inflammatory vascular disease. I hypothesize that development and application of “global lipidomic arrays” will define how lipids are regulated during vascular cell differentiation and inflammation, will identify new markers, and open up new therapeutic strategies. These aims go beyond the current state of the art, and will be achieved by the following objectives that include novel interdisciplinary concepts and approaches: 1. Develop analytical methodologies using Fourier transform mass spectrometry and bioinformatics. 2. Develop approaches for structural identification, using high resolution MSn, high sensitivity NMR, and new computational methodologies. 3. Define the size and diversity of the mammalian cellular lipidome in human platelets (validation). 4. Characterize the global lipidome in (i) monocytes during differentiation from stem /yolk cells to resident, inflammatory or foam cells, (ii) plasma from samples genomically characterized for 14 separate risk alleles for cardiovascular and Alzheimer’s disease. 5. Develop an open access web-based resource for storage and curation of the results to allow others to mine the data.";2969345,4;2969345,4;ERC-2013-ADG;/ERC-AG;CARDIFF UNIVERSITY;UK;UNIVERSITY COLLEGE LONDON;UK;"/LIF;/MED;/MBI";1;0;0;1;0;0 107849;313755;BODILY SELF;ONG;FP7-IDEAS-ERC;ERC-SG-SH4;FP7;Embodied Minds and Mentalised Bodies;2013-04-01;2018-09-30;;"How does our acting, sensing and feeling body shape our mind? The mechanisms by which bodily signals are integrated and re-represented in the brain, as well as the relation between these processes and body awareness remain unknown. To this date, neuropsychological disorders of body awareness represent an indispensible window of insight into phenomenally rich states of body unawareness. Unfortunately, only few experimental studies have been conducted in these disorders. The BODILY SELF will aim to apply methods from cognitive neuroscience to experimental and neuroimaging studies in healthy volunteers, as well as in patients with neuropsychological disorders of body awareness. A first subproject will assess which combination of deficits in sensorimotor afferent and efferent signals leads to unawareness. The second subproject will attempt to use experimental, psychophysical interventions to treat unawareness and measure the corresponding, dynamic changes in the brain. The third subproject will assess how some bodily signals and their integration is influenced by social mechanisms. The planned studies surpass the existing state-of-the-art in the relevant fields in five ground-breaking ways, ultimately allowing us to (1) acquire an unprecedented ‘on-line’ experimental ‘handle’ over dynamic changes in body awareness; (2) restore awareness and improve health outcomes (3) understand the brain’s potential for reorganisation and plasticity in relation to higher-order processes such as awareness; (4) understand how our own body experience is modulated by our interactions and relations with others; (5) address in a genuinely interdisciplinary manner some of the oldest questions in psychology, philosophy and medicine; how embodiment influences the mind, how others influence the self and how mind–body processes affect healing.";1453284;1453284;ERC-2012-StG_20111124;/ERC-SG;UNIVERSITY COLLEGE LONDON;UK;;;/SOC;1;0;0;1;0;0 87411;205557;EMPATHICBRAIN;ONG;FP7-IDEAS-ERC;ERC-SG-LS4;FP7;Plasticity of the Empathic Brain: Structural and Functional MRI Studies on the Effect of Empathy Training on the Human Brain and Prosocial Behaviour;2008-09-01;2014-08-31;;Social neuroscientists study the neural mechanisms underlying our capacity to understand our own and other people’s feelings. Despite neuroscientists’ advances in plasticity research and empathy research, little is known about cortical and behavioural plasticity in emotion understanding and empathy. Clearly, in today’s world, acquiring the capacity to effectively enhance empathy and prosocial behaviour is of the utmost importance. In the present project, we will investigate the malleability of empathy via training. We will adopt a multimethod and interdisciplinary approach, combining techniques and paradigms from the fields of neuroscience, (bio-)psychology, and economics. Studies 1-3 will provide a cross-sectional look at structural and functional differences in the brains of individuals scoring high vs. low on empathy, of those with pathological deficits in empathy (psychopaths, alexithymics), and of individuals starting vs. finishing a three-year training program in Carl Rogers’ person-centred therapy, which aims to increase emotional capacity and empathy. Study 4 will examine brain plasticity using real-time fMRI: Participants will learn to self-regulate brain activity through the use of immediate feedback from emotion-related brain areas while practicing certain mental techniques. In Study 5, a small-scale longitudinal study, healthy individuals will receive extensive training by professional instructors in either empathy- or memory-enhancing techniques previously developed in the East and the West. We will measure training-related changes in brain structure and functioning, in hormone levels, and in behaviour. Evidence for emotional brain plasticity in adults and children would not only have important implications for the implementation of scientifically validated, effective training programs for schools and for economic and political organizations, but also for the treatment of the marked social deficits in autistic and psychopathic populations.;1499821;1499821;ERC-2007-StG;/ERC-SG;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;DE;UNIVERSITAT ZURICH;CH;"/BIO;/LIF;/MED";1;0;0;1;0;0 97540;264564;LHCPHENONET;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-ITN;FP7;Advanced Particle Phenomenology in the LHC era;2011-01-01;2014-12-31;http://www.lhcphenonet.eu/;The Large Hadron Collider (LHC) at CERN is the largest and most complex single experiment ever performed in the history of mankind. The physics program of the LHC is motivated by fundamental questions about the laws of nature, such as explaining the origin of mass, understanding the early universe and the structure of space and time, unravelling the nature of dark matter and providing glimpses of extra spatial dimensions or grand unification of forces. Any of these insights would definitely constitute a revolution in our view on the world. The LHCPhenoNet unites throughout Europe young and energetic leadership in theoretical particle physics with emphasis on LHC phenomenology. Most of its team and task leaders have made highly significant and innovative contributions in the last years within the theory of strong interactions, Quantum Chromodynamics (QCD), or the electroweak sector of the SM by addressing key issues at the interface to the experiments. The network members are poised to lead the theoretical particle physics community to meet the new challenges presented by LHC physics and to provide in a unified European effort excellent training for young theoretical physicists in this field, at both the doctoral and post-doctoral level. With the challenges of the machine operation driving the LHC start-up, the proposed timeline of the initial training network matches the currently foreseen LHC running schedule and thus allows full exploitation and interpretation of the early data. The field of theoretical particle physics is also currently driven by the development of customized open-source software as well as by applications of products from commercial enterprises especially in the field of symbolic manipulation and computer algebra, such as Maple and Mathematica from our private sector partners. The proposed network LHCPhenoNet is designed to provide optimal training conditions for early stage researchers in an interdisciplinary environment.;4491085,87;4491085,87;FP7-PEOPLE-2010-ITN;/MC-ITN;AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS;ES;"UNIWERSYTET SLASKI;DEBRECENI EGYETEM;UNIVERSITY OF DURHAM;UNIVERSITAT ZURICH;UNIVERSIDAD DE BUENOS AIRES;RISC SOFTWARE GMBH;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;STIFTUNG DEUTSCHES ELEKTRONEN-SYNCHROTRON DESY;STICHTING NEDERLANDSE WETENSCHAPPELIJK ONDERZOEK INSTITUTEN;ISTITUTO NAZIONALE DI FISICA NUCLEARE";"PL;HU;UK;CH;AR;AT;FR;DE;NL;IT";"/EDU;/NET";1;0;0;1;0;0 108094;313797;COEVOLVE;ONG;FP7-IDEAS-ERC;ERC-SG-SH3;FP7;From Forest to Farmland and Meadow to Metropolis: What Role for Humans in Explaining the Enigma of Holocene CO2 and Methane Concentrations?;2013-05-01;2018-04-30;;"The Holocene record of atmospheric CO2 and methane concentrations is an enigma. Concentrations of both gases increased from the beginning of the epoch 11,700 years ago to about 10,000 BP, then declined for several thousand years, but by 6000 BP, concentrations of both gases were steadily increasing again. This mid-late Holocene rise in greenhouse gases is unusual; similar patterns are not observed during previous interglacials. While various mechanisms have been proposed to explain these changes in Holocene CO2 and methane, there is one undisputed feature of this epoch that we know is different from the rest of Earth history: the existence of behaviorally modern humans. How humanity could have influenced the Holocene increase in CO2 and methane concentrations is the subject of the COEVOLVE project. In an interdisciplinary study that combines the social and natural sciences, we will reconstruct anthropogenic CO2 and methane emissions over the Holocene using a state-of-the-art model of terrestrial biogeochemistry and earth surface processes. The novelty of our approach is to develop a geodatabase of anthropogenic activities derived from historical and archaeological observations to drive our model, and to evaluate our simulations against a new, comprehensive global reconstruction of past land cover. COEVOLVE is organized around three activities: 1) synthesis of observations of past land cover change from paleoecological archives, 2) development of a spatial database of the spread of technology, industry, culture, and trade that influenced global land use and resource consumption patterns and 3) informed by parts 1 and 2, modeling of terrestrial biogeochemical cycles and land surface processes including deforestation, soil erosion, and fire. With a new perspective on preindustrial environmental impact, the COEVOLVE project will make a breakthrough in our understanding of the influence of humans on greenhouse gas concentrations and global climate during the Holocene.";1500000;1500000;ERC-2012-StG_20111124;/ERC-SG;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;DE;"UNIVERSITE DE LAUSANNE;UNIVERSITE DE GENEVE";CH;/SOC;1;0;0;1;0;0 105344;317382;NITIMESR;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-ITN;FP7;A Networked and IT-enabled Firm's Perspective on Crisis Management;2012-10-01;2016-09-30;;"By the middle of the year, experts announced 2011 to be the most expensive year in counts of global disaster damages ever. The EU has articulated its ambition to become an effective player in crisis management as part of the European Security Strategy (Stockholm Programme 2010-2014, Lisbon Treaty). The Hyogo Framework stipulates that a substantial reduction of disaster losses is only possible through advanced governance and management. NITIMesr has been designed as a practice-inspired research initiative that addresses • research and conceptualization of new modes and competencies for coordination and collaboration in heterogeneous actor networks including involvement of individuals, • advanced practices of vertically integrating governance of crisis management, strategic and operative management, with a special focus on • involvement and engagement of self-motivated individuals - actors, agents, volunteer, citizens or, as we call them - entrepreneurs. NITIMesr brings together an interdisciplinary group of researchers and industry partners including the two leading European security clusters around the international court of justice in Den Haag and the Bavarian Security Cluster around the International Campus Aerospace and Security, BICAS, at the German EADS headquarters in Munich. The aim is to explore new frontiers of safety and security with the institutional, governance, organizational and managerial challenges of crisis networks, to develop and test innovative approaches for coordination in real world settings and to build Europe-wide connected clusters for crisis management and implement integrated solutions. Both clusters expect universities to provide the key success factor “talent” through leadership for joint research, education, development and career development. The role of this ITN is to provide initial resources to establish European-level leadership to build research and training capacities in the security clusters on advanced crises management.";3655652,2;3655652,2;FP7-PEOPLE-2012-ITN;/MC-ITN;Stichting CETIM - CENTER FOR TECHNOLOGY AND INNOVATION MANAGEMENT;NL;"UNIVERSITEIT LEIDEN;UNTERNEHMENSBERATUNG H&D GMBH;AON GROEP NEDERLAND BV;FUNDACIO PRIVADA UNIVERSITAT I TECNOLOGIA;WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER;UNIVERSITAET DER BUNDESWEHR MUENCHEN";"NL;DE;ES";/LIF;1;0;0;1;0;0 186366;626775;OCEANDATAMODELS;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IOF;FP7;Statistical modelling and estimation for spatiotemporal data with oceanographic applications;2014-04-01;2017-03-31;;"This fellowship is concerned with building new statistical modelling and estimation procedures that are appropriate for Big Data challenges with high-dimensional dependent data. The new methods will be applied to large oceanographic spatiotemporal datasets leading to important application benefits in global climate modelling. The methodological contribution centres on building physically-motivated stochastic processes that capture multivariate dependence structure from complex high-dimensional data sets. Estimation procedures are then developed to capture heterogeneity in spatiotemporal data, while properly accounting for practical issues such as irregularly-sampled data in space and time. Such modelling and estimation procedures provide great interpretability and meaningful summaries from the complex data sets we observe. The societal benefits include improved global climate modelling and improved responses to environmental disasters such as oil spills. These advances will be achieved through interdisciplinary collaboration, with the fellow working closely with world-leading experts in oceanographic data in the US during the outgoing phase, and then consolidating these developments at the UCL Department of Statistical Sciences in the return phase. The fellow will therefore gain experience in developing relevant new statistical methods for a pressing Big Data challenge, and will then return to Europe where this training will significantly develop the fellow’s ability to produce cutting-edge research at the frontier of statistics and numerous applications involving complex high-dimensional data.";294219,6;294219,6;FP7-PEOPLE-2013-IOF;/MC-IOF;UNIVERSITY COLLEGE LONDON;UK;;;/LIF;1;0;0;1;0;0 88400;211911;EFRAIM;ONG;FP7-KBBE;KBBE-2007-2-2-06;FP7;Mechanisms of early protective exposures on allergy development;2008-02-01;2012-01-31;http://www.efraim-online.com;Allergy has developed into a major health concern in Europe. Allergic diseases can currently be managed effectively but not cured. The onset of allergies stars early in life and there is increasing evidence that exogenous factors affecting the incidence of these illnesses exert their effect early in life, in part even prenatally. The highly interdisciplinary EFRAIM project will prospectively investigate the main protective factors in early life influencing the development of allergies in birth cohorts conducted in allergy protective environments in five European countries. These birth cohorts have been enrolling over 1,000 children and have collected detailed information on the onset of allergic illnesses, objective measures of allergies and a vast amount of information about a number of environmental exposures. Large biobanks with a variety of biological samples have been established. In the EFRAIM project particular attention will be given to the potential role of dietary exposures, lifestyle and other environmental (e.g. microbial) exposures early in life which are causal determinants rather than triggers of the illness. The mechanisms mediating these protective exposures such as the maturation of immune responses, gut colonisation, the mucosal barrier function and the genetic and epigenetic factors interacting with the environmental exposures will be investigated. The knowledge about protective exposures early in life can be turned into the development of preventive strategies. The EFRAIM project will actively address two routes of preventive interventions in animal models and in vitro studies: the development of an allergy protective milk formula and the development of an allergy vaccine. Both approaches are based on knowledge gained in the human studies. The EFRAIM project is expected to produce ground-breaking new insights on protective agents and their mechanisms that can be used to prevent the further development of allergies.;3915718;2988000;FP7-KBBE-2007-1;/CP-FP;LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN;DE;"PHILIPPS UNIVERSITAET MARBURG;UNIVERSITAT BASEL;UNIVERSITAET ULM;UNIVERSITE DE FRANCHE-COMTE;TECHNISCHE UNIVERSITAET MUENCHEN;COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES;UNIVERSITAET BERN;MEDIZINISCHE HOCHSCHULE HANNOVER;TERVEYDEN JA HYVINVOINNIN LAITOS;UNIVERSITAT ZURICH;KARDINAL SCHWARZENBERG'SCHES KRANKENHAUS BETRIEBSGESELLSCHAFT MBH;Protectimmun GmbH;UNIVERSITEIT UTRECHT;TEAGASC - AGRICULTURE AND FOOD DEVELOPMENT AUTHORITY";"DE;CH;FR;FI;AT;NL;IE";"/ABI;/ENV;/MED;/MBI";1;0;0;1;0;0 95664;260821;PROTOBRAIN;ONG;FP7-IDEAS-ERC;ERC-SG-LS8;FP7;Sensory-motor circuits in marine zooplankton and early evolution of the nervous system;2010-10-01;2015-09-30;;"Animal nervous systems evolved in a marine environment at the dawn of animal life, and diversified during the Cambrian explosion', one of the most spectacular events in the history of life. Remarkably little is known about early stages of the evolution of neuronal circuits and nervous systems. Simple marine planktonic organisms, in particular ciliated larvae of various marine invertebrates, can give us insights into how simple nervous circuits of marine organism function and may have evolved. The proposed project aims at investigating the nervous system of ciliated animal larvae using an integrative approach combining the fields of molecular biology, neurobiology, behaviour, marine ecology and evolution. As such, the project aims at pioneering an entirely new field of interdisciplinary investigations, the neurobiology of marine zooplankton. We will use a cultured marine annelid as our main model species, and several 'satellite' species to give a comparative perspective to our investigations. Our objective is to understand the anatomy and function of neuronal circuits that regulate the planktonic migration of ciliated zooplankton larvae. We will be able to address this at various levels, linking molecules to neuron types, neurons to larval behaviours and behaviours to marine ecology. Our aim is to get the first detailed systems level understanding of the nervous system of a marine ciliated larva.";1270800;1270800;ERC-2010-StG_20091118;/ERC-SG;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;DE;;;"/BIO;/LIF";1;0;0;1;0;0 94306;249247;PFERLS;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-RG;FP7;Role of the Pollen-expressed FERONIA-like Receptor-like Kinases during Plant Fertilization;2010-04-08;2013-04-07;;Fertilization relies on complex and specialized mechanisms that achieve the precise delivery of the male gamete to the female gamete and their subsequent union. In plants, the molecular mechanisms that mediate the discharge of sperm cells by the male gametophyte (pollen tube) into the female gametophyte are still a mystery although they are of great interest for the manipulation of breeding barriers in wide-crosses and the production of hybrids. Recently, it was shown that a molecular dialogue between the male and female gametophytes must occur for successful sperm discharge. A receptor-like kinase called FERONIA has been shown by U. Grossniklaus’s group (UZH, Switzerland), the Host Laboratory, to be required for this dialogue in the female gametophyte. The French Research Fellow Aurélien Boisson-Dernier initiated this project in his former laboratory (J. Schroeder’s group, UCSD, USA) and recently (November 16th 2008) joined U. Grossniklaus’s group to characterize PFERL-RLKs (pollen-expressed FERONIA-like receptor-like kinases), which are excellent candidates to assume the role of the FER counterpart in the male gametophyte. The project and the Research Fellow’s career will greatly benefit from the training and expertise offered by the Host Lab, as well as from its on-going in-depth characterization of FER-dependent signaling. This highly interdisciplinary proposal that includes molecular and cell biological, cytological, genetic, biochemical, and interactome approaches should result in the identification of the first components of the FER signaling counterpart in the pollen tube, essential for male-female gametophytic interactions and fertilization. Consequently, this project will allow the Research Fellow to establish himself as an independent leading scientist in Europe exploiting (i) this novel niche in the plant fertilization field, (ii) the new skills he will acquired in the Host Lab, and (iii) the scientific network he will develop during at the Host Lab.;75000;75000;FP7-PEOPLE-2009-RG;/MC-IRG;UNIVERSITAT ZURICH;CH;;;/SCI;1;0;0;1;0;0 98109;264296;BIONUT;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-ITN;FP7;BIOchemical and genetic dissection of control of plant mineral NUTrition;2011-01-01;2014-12-31;;The main objective of BIONUT-ITN is to provide state-of-the-art training for young researchers in the highly strategic field of plant nutrition and productivity through an international programme of research, training and transfer of knowledge. The interdisciplinary training will include biochemical and genetic technology in the laboratory with field agronomy and high throughput phenotyping technologies, combining inputs from academia and industry. The training will be based around a research project which will address important biological questions using model plants and the major crop species, wheat and rice, with the overall goal of increasing the understanding of genetic control of nutrient use efficiency of plants and thus addressing one of the major challenges of European society, global food security. The overarching and long term scientific questions of BIONUT-ITN are: what controls nutrient use efficiency of plants and how can we use this knowledge to generate crop plants with optimised yields without increasing inputs? BIONUT-ITN addresses this by bringing together a group of world class researchers to adopt a multidisciplinary approach and to provide the necessary breadth of academic as well as industrial expertise essential to training and transfer of knowledge. The scientific themes providing the backbone of our training activities are (1) Genetic control of nutrient use efficiency, (2) Function of new genes affecting plant mineral nutrition, and (3) From the laboratory to the field. By bringing complementary intersectoral providers of research training together into a cohesive network, BIONUT-ITN will move the biologists working in the field of plant nutrition closer to the end-users of the research achievements including agroindustry, breeders and farmers and as a consequence, enhance the career prospects of the trainees.;2422034;2422034;FP7-PEOPLE-2010-ITN;/MC-ITN;JOHN INNES CENTRE;UK;"CROPDESIGN NV;INSTYTUT BIOCHEMII I BIOFIZYKI POLSKIEJ AKADEMII NAUK;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG;UNIVERSITA DEGLI STUDI DI MILANO;ROTHAMSTED RESEARCH LIMITED;RIJKSUNIVERSITEIT GRONINGEN;INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE";"BE;PL;DE;IT;UK;NL;FR";"/EDU;/NET";1;0;0;1;0;0 192367;337977;FFP;ONG;FP7-IDEAS-ERC;ERC-SG-SH2;FP7;Families and food poverty in three European Countries in an Age of Austerity;2014-05-01;2019-04-30;;Food poverty in the global North is emerging as an urgent social and moral concern, increasingly recognized as a central issue in the field of health inequalities in industrialized countries. With widening income disparity in Austerity Europe and ‘the end of cheap food’, these effects are being exacerbated. International media report an increase in the number of children arriving at school hungry, a dramatic rise in the number of food banks handing out food parcels to families and parents forced to choose between ‘heating and eating’. However, little is known about how food practices are negotiated in low-income families, children’s and young people’s perspectives of food poverty and how it affects their lives, or how food poverty manifests and is addressed in different places. The proposed interdisciplinary, ambitious and innovative study will answer such questions, breaking new ground by: a) applying a mixed method international comparative case study design to the study of household food poverty b) including the experiences of children and young people using both extensive and intensive data and c) drawing on methodological developments in the sociology of food and consumption to elucidate habitual behaviour. Providing for ‘a contrast of contexts’ in relation to conditions of austerity, the study focuses on Portugal, where poor families with children have been most affected by economic retrenchment, the UK, which is experiencing substantial cuts in benefits to poor families, and Norway which, in comparison with most societies, is highly egalitarian and has not been subject to austerity measures. Building on the Principal Investigator’s (PI’s) current mixed-methods UK research on families, food and paid work, the project will develop the PI’s research skills, publication record and international reputation. Engaging academic and non-academic beneficiaries at various stages of analysis and dissemination the study will achieve societal as well as scientific impact.;1370937,49;1370937,49;ERC-2013-StG;/ERC-SG;UNIVERSITY COLLEGE LONDON;UK;"INSTITUTE OF EDUCATION, UNIVERSITY OF LONDON;Associaç?o para Investigaç?o e Desenvolvimento da Faculdade de Medicina;OSLOMET - STORBYUNIVERSITETET;STATENS INSTITUTT FOR FORBRUKSFORSKNING;INSTITUTO DE CIENCIAS SOCIAIS";"UK;PT;NO";/SOC;1;0;0;1;0;0 99166;273195;ICPAL;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-IOF;FP7;Investigation of Cooperative Phenomena on the Atomistic Level;2012-01-01;2016-05-24;;"'Cooperative phenomena are ubiquitous in science. They occur when a sufficient number of particles interact and lead to phenomena that can only be explained by taking into account the whole ensemble. It is a fundamental, but still open, question how these cooperative phenomena begin and how the transition from single particle movement to hydrodynamics takes place. This question becomes increasingly relevant with nanotechnological applications reaching smaller and smaller scales. The proposed project puts forward an investigation of cooperative phenomena on the atomistic level. The proposed fellow will use an interdisciplinary approach to employ both computer simulations (outgoing host: University of California, Berkeley) and experiments (return host: Max-Planck-Institute for Extraterrestrial Physics, Germany). The experiments will be conducted using 'complex plasmas', which consist of micrometer-sized particles suspended in a weakly ionized gas. The particles can be visualized individually, allowing an investigation of their movement on the atomistic level. The fellow has already conducted experiments with mesoscopic complex plasmas on fluid effects and hydrodynamic instabilities. She will first build upon these studies and complement them with MD simulations of the particle movement. Then the fellow will use the expertise gained in the first simulations to numerically study the transition to hydrodynamics and the onset of cooperative phenomena. Finally, these simulations will be used to make predictions for additional experimental studies. This will make possible a comprehensive view of the underlying phenomena. This multidisciplinary project will add to the scientific and complementary skills of the fellow and significantly broaden the understanding of fluid physics on small scales. This way, the fellow will increase the knowledge in this interesting topic, transfer know-how to Europe and help Europe remain at the cutting edge of this fundamental research area.'";221920;221920;FP7-PEOPLE-2010-IOF;/MC-IOF;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;DE;;;"/EMP;/SOC;/COO";1;0;0;1;0;0 93452;236792;SACP;ONG;FP7-PEOPLE;FP7-PEOPLE-IEF-2008;FP7;Role of Senescence-associated Cysteine Proteases;2010-03-01;2010-11-30;;Despite the importance of senescence in world food production and safety, the proteases responsible for the massive protein degradation during senescence have not been identified. Strong candidates for senescence-associated proteases are members of various cysteine protease families that localize in lytic vacuoles that presumably engulf the chloroplast during senescence. This project aims at identifying the proteases that degrade chloroplasts in the model plant Arabidopsis thaliana. To detect and identify the active proteases during senescence the Activity-based Protease Profiling (ABPP) will be applied. ABPP is a novel functional proteomics technology based on the use of labeled small molecule inhibitors that label proteases in an activity-dependent manner. This technology can be used to show where, when and which proteases are active during senescence, and will reveal proteases that act redundantly. The role of these proteases in senescence will be further studied using reverse genetics and cell biological approaches. This project extends on the expertise and interest of the applicant in senescence and provides an excellent interdisciplinary training in cell biology, molecular cloning and state-of-the-art chemical biology. By performing this work in the Plant Chemetics lab at the Max Planck institute for Plant Breeding Research in Cologne, the applicant will have access to one of the best research and training facilities in Europe and leave at the end of the project with the knowledge and materials to establish an independent scientific career.;160996,91;160996,91;FP7-PEOPLE-IEF-2008;/MC-IEF;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;DE;;;"/SCI;/EMP";1;0;0;1;0;0 92418;242933;NANOTRANS;ONG;FP7-IDEAS-ERC;ERC-SG-LS3;FP7;Biomolecular Motor Systems: From Cellular Function to Nanotechnological Applications;2009-11-01;2015-10-31;;"This interdisciplinary project aims (i) to understand intracellular transport processes on a molecular level using novel nano-optical imaging tools and (ii) to use the insight from cellular systems to operate biomolecular motor systems in engineered environments for the fulfillment of complex nanotechnological tasks. Building on experience in optical microscopy and single molecule biophysics the research group will develop and apply nanotechnology-based tools to study the dynamical functioning of microtubule-based motor proteins in vitro and in vivo with nanometer resolution in three dimensions. These studies are expected to broaden the general knowledge about the design principles of molecular machines as well as the principles by which they interact with each other. This knowledge will - in return - pave the road for applications of these highly evolved transport machineries for a wide range of self-organizing nanofunctions in engineered environments. In contrast to conventional "macroscopic" top-down or "atomic" bottom-up approaches, a driving factor for this research is the capability of cellular machines to work in parallel, thus enabling the efficient fabrication and detection of nanostructures. The project will be strongly focussing on the interface between molecular cell biology and nanotechnology. With respect to the applied ERC funding, the project goals can be described by: Goal 1: Single-molecule studies on motor proteins using optical 3D-nanometer imaging, Goal 2: Investigation of cooperative effects in multi-motor transport, Goal 3: External control over transport systems in engineered environments, and Goal 4: Application of motor systems for nano-manipulation and nano-detection. Regarding the long-term goal, it is envisioned to let smart nanomaterials fulfill biological functions in cellular systems and to efficiently operate biomolecular machines in engineered environments.";1956000;1956000;ERC-2009-StG;/ERC-SG;TECHNISCHE UNIVERSITAET DRESDEN;DE;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;DE;"/BIO;/LIF";1;0;0;1;0;0 98593;268782;ARCID;ONG;FP7-IDEAS-ERC;ERC-AG-LS1;FP7;The Role of Arl Proteins in Retinal and other Ciliary Diseases;2011-04-01;2016-03-31;;"Arl (Arf-like) proteins, GTP-binding proteins of the Ras superfamily, are molecular switches that cycle between a GDP-bound inactive and GTP-bound active state. There are 16 members of the Arl subfamily in the human genome whose basic mechanistic function is unknown. The interactome of Arl2/3 includes proteins involved in retinopathies and other ciliary diseases such as Leber?s Congenital Amaurosis (LCA) and kidney diseases such as nephronophthisis. Arl6 has been found mutated in Bardet Biedl Syndrome, another pleiotropic ciliary disease. In the proposed interdisciplinary project I want to explore the function of the protein network of Arl2/3 and Arl6 by a combination of biochemical, biophysical and structural methods and use the knowledge obtained to probe their function in live cells. As with other subfamily proteins of the Ras superfamily which have been found to mediate similar biological functions I want to derive a basic understanding of the function of Arl proteins and how it relates to the development and function of the ciliary organelle and how they contribute to ciliary diseases. The molecules in the focus of the project are: the GTP-binding proteins Arl2, 3, 6; RP2, an Arl3GAP mutated in Retinitis pigmentosa; Regulators of Arl2 and 3; PDE? and HRG4, effectors of Arl2/3, which bind lipidated proteins; RPGR, mutated in Retinitis pigmentosa, an interactor of PDE?; RPGRIP and RPGRIPL, interactors of RPGR mutated in LCA and other ciliopathies; Nephrocystin, mutated in nephronophthisis, an interactor of RPGRIP and Arl6, mutated in Bardet Biedl Syndrome, and the BBS complex. The working hypothesis is that Arl protein network(s) mediate ciliary transport processes and that the GTP switch cycle of Arl proteins is an important element of regulation of these processes.";2434400;2434400;ERC-2010-AdG_20100317;/ERC-AG;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;DE;;;"/BIO;/LIF";1;0;0;1;0;0 97659;258677;CURELUNG;ONG;FP7-HEALTH;HEALTH.2010.2.4.1-6;FP7;Determining (epi)genetic therapeutic signatures for improving lung cancer prognosis;2011-01-01;2014-06-30;http://www.curelung.eu/;Lung cancer (LC) is still the most lethal type of cancer worldwide. The extremely poor prognosis for LC patients is partly due to the lack of effective therapies. At present, most patients with pulmonary carcinomas are treated with chemotherapy. This essentially consists of classic cytotoxic drugs which only improve survival in small cohorts in few cases. In spite of the rapidly growing understanding of the epigenetic and genetic profile of LC, such knowledge has contributed little to improving therapeutics. This scenario, however, is likely to change soon because several specific cancer therapies, targeting molecules that are altered in cancer, are being developed or are already undergoing clinical trials. Thinking ahead, our proposal focuses, on the one hand, on validating novel and specific therapeutic strategies, with particular emphasis on discovering (epi)genetic alterations that could act as novel targets for therapies, and, on the other, on defining the (epi)genetic markers that could determine the efficacy response or resistance to targeted therapies as well as the acquired resistance of the tumours to therapy. To reach our goals, we have designed an integrative and interdisciplinary approach involving leading European clinical scientists of international renown with prominent preclinical and basic research groups using high throughput and state-of-the art platforms for genomics and gene expression analysis. To date, no such comprehensive information exists. The results will be of great value for the stratification of lung tumours according to their genetic background for tailored treatments. The development of an (epi)genetic-based therapeutic prediction model will hopefully set the basis for future tailored treatment of LC as well as of other epithelial cancers.;3849117,33;2965749;FP7-HEALTH-2010-two-stage;/CP-FP;FUNDACIO INSTITUT D'INVESTIGACIO BIOMEDICA DE BELLVITGE;ES;"INSTITUT GUSTAVE ROUSSY;KLINIKUM DER UNIVERSITAET ZU KOELN;FUNDACION PARA LA INVESTIGACION MEDICA APLICADA FIMA;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;UNIVERSITA DEGLI STUDI DI TORINO;MRC HOLLAND B.V.;Krzysztof Kucharczyk Techniki Elektroforetyczne Spzoo;UNIVERSITE JOSEPH FOURIER GRENOBLE 1;THE UNIVERSITY OF LIVERPOOL;FONDAZIONE IRCCS ISTITUTO NAZIONALE DEI TUMORI";"FR;DE;ES;IT;NL;PL;UK";"/MED;/MBI";1;0;0;1;0;0 98704;268543;WEBOFLIFE;ONG;FP7-IDEAS-ERC;ERC-AG-LS8;FP7;Robustness of The Web of Life in the Face of Global Change;2011-05-01;2017-04-30;;Recent work on complex networks has provided a theoretical framework to unravel the structure of the Web of Life. Yet, we still know little on the implications of network architecture for the robustness of beneficial network services such as pollination of crop plants. In this proposal, I intend to move beyond current studies of global environmental change that have mainly focused on its consequences for the abundance, phenology, and geographic distributions of independent species, to embrace effects for the network of interactions among species. My strategy to tackle this overall goal is through a synthetic and interdisciplinary approach that combines theory, meta-analysis, and experiment. First, I will integrate a large dataset of ecological networks with phylogenies and life-history traits to simulate the rate and shape of loss of functional groups. Second, I will set up an experimental design to address how two important ecosystem services, pollination and control of insect pests, decline with network disassembly. Third, I will explore early-warning signals of network collapse that may predict the proximity of a critical threshold in the driving forces of global change. My approach can provide a starting point for assessing the community-wide consequences of the current biodiversity crisis.;1700000;1700000;ERC-2010-AdG_20100317;/ERC-AG;UNIVERSITAT ZURICH;CH;AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS;ES;"/BIO;/LIF";1;0;0;1;0;0 87726;212683;GOODWATER;ONG;FP7-PEOPLE;PEOPLE-2007-1-1-ITN;FP7;RESEARCH TRAINING FOR GOOD EUROPEAN GROUND WATER RESOURCES;2008-09-01;2012-08-31;;On 1st January 2007 the Ground Water sub-directive (COM/2003/550) complementing the European Water Framework Directive (COM/2000/60/EC) came into force. These two directives enforce the protection, maintenance and sustainable use of groundwater resources in the European Union. However, today around 750 000 sites are contaminated with substances including hydrocarbons, chlorinated solvents, and diffuse organic contaminants throughout Europe. Microbial processes can play an important role in the remediation and protection of groundwater resources and there is an urgent need for a better integration of microbial process understanding in current management schemes. Groundwater management must take into account different characteristics and degradation capacities for pollutants and sites, and requires a comprehensive understanding of contaminant fate, degradation pathways, and remediation potentials. Today, in Europe there is a shortage of scientists and environmental engineers with the interdisciplinary understanding of groundwater contaminant behaviour required when embarking on the tasks of protecting and sustainably managing groundwater resources, remediating existing contaminations, and performing risk assessment. The aim of the GOODWATER ITN is to educate a new generation of groundwater professionals with targeted multidisciplinary expertise and process understanding, including microbiological, hydrogeological, chemical, and stable isotope aspects. For this purpose, some of Europe’s most esteemed groundwater experts from the different fields join forces to guarantee a cutting-edge scientific research training platform. The network will offer individual expert training by research, and network-wide training by workshops, summer schools, and laboratory exchange. Moreover, stakeholders from industry and authorities will be involved as associated partners to steer the project towards socio-economic relevance and tutor relevant complementary skills.;3616822,8;3616822,8;FP7-PEOPLE-2007-1-1-ITN;/MC-ITN;HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH;DE;"VLAAMSE INSTELLING VOOR TECHNOLOGISCH ONDERZOEK N.V.;UNIVERSITEIT GENT;UNIVERSITE CATHOLIQUE DE LOUVAIN;Geological Survey of Denmark and Greenland;DANMARKS TEKNISKE UNIVERSITET;KATHOLIEKE UNIVERSITEIT LEUVEN";"BE;DK";"/EMP;/SOC;/EDU";1;0;0;1;0;0 105343;317235;CO2-REACT;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-ITN;FP7;Geologic Carbon Storage;2013-03-01;2017-02-28;http://www.see.leeds.ac.uk/co2react/;"The CO2-REACT ITN has been created to address twin objectives: (1) to provide urgently needed training in CO2 storage preparing candidates for critical roles in the coming years and (2) to significantly advance our understanding of the fate and consequences of CO2 injection into the subsurface during carbon storage efforts. The CO2-REACT ITN addresses these objectives through a balanced combination of 6 academic and 6 industrial teams. The academic partners have been selected for their unique and diverse expertise in the reactivity of carbonate phases at scales ranging from the atomic to the field scale. The six industry partners were selected to represent a spectrum of the largest stakeholders in CO2 storage. By formally joining these teams, we are creating a training/research platform that is unique in the world in its ability to understand the fate and consequences of CO2 injected into subsurface reservoirs using an impressive array of experimental and modeling techniques. CO2-REACT aims to train 13 ESRs and 1 ER, through an integrated and coherent set of research and training activities that will significantly improve our understanding of the consequences of injecting CO2 into the subsurface. We chose this technical focus because: (1) new knowledge is essential for solving a critical societal problem, (2) the problem is interdisciplinary, requiring input from chemistry, geology, physics, chemistry, hydrology and engineering, (3) producing solutions that industry can implement will promote tight academia-industry collaboration, a true plus for the trainees and and 4) by focusing on a single theme, close interaction and collaboration among the CO2-REACT teams is fostered. An additional societal objective of CO2-REACT is help to raise public awareness to the needs, challenges and safety issues in subsurface CO2 storage through public outreach efforts.";3900802,18;3900802,18;FP7-PEOPLE-2012-ITN;/MC-ITN;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FR;"MAERSK OLIE OG GAS AS;KOBENHAVNS UNIVERSITET;WEST SYSTEMS SRL;LAFARGE CENTRE DE RECHERCHE SAS;AMPHOS 21 CONSULTING SL;UNIVERSITY OF LEEDS;UNIVERSIDAD DE OVIEDO;ORKUVEITA REYKJAVIKUR SF;WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER;HASKOLI ISLANDS";"DK;IT;FR;ES;UK;IS;DE";/LIF;1;0;0;1;0;0 90617;239164;MRNA DECAY;ONG;FP7-PEOPLE;PEOPLE-2007-4-3.IRG;FP7;Molecular mechanisms of mRNA decay;2009-07-01;2013-06-30;;"All organisms require a reliable mechanism to turn genes on and off. This regulation of gene expression underlies cellular processes ranging from the response to environmental signals to the development of multi-cellular organisms and cell-cell communication. Understandably, the cell tightly controls gene expression at every step from DNA to protein. Recent work has given new insights into these control mechanisms and revealed dedicated pathways (including non sense mediated decay) that target mRNA for degradation, thereby efficiently turning genes off. Here, we propose to study the molecular mechanism that underlies the degradation of mRNA. Although many of the proteins involved have been identified, little is know about how the activity of the degradation machinery is regulated on an atomic level. We will study one of the core components, the DCP1:DCP2 decapping complex, that removes the protecting 5' cap structure from the mRNA. Specific question we will address range from the structure of the complex in solution, the catalytically important molecular motions and the way protein-protein or protein-RNA interactions can either activate or inhibit the activity of the decapping complex. We will use of nuclear magnetic resonance spectroscopy, to study these structure, motions and interactions. As these complexes involved can be of high molecular weight, we will exploit recently developed NMR methodology in concert with novel sample preparation techniques. In addition, we will extend our structural studies with in-vivo studies, where we can study the effect of mutations in residues that were found to be important for function. The interdisciplinary nature of this project and the use of a state-of-the-art structural approach promises to provide unique insights into the way cells regulate gene expression by removing mRNA from the transcriptional pool.";100000;100000;FP7-PEOPLE-IRG-2008;/MC-IRG;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;DE;;;"/SCI;/COO";1;0;0;1;0;0 100178;282008;DYNAMOM;ONG;FP7-IDEAS-ERC;ERC-SG-LS1;FP7;New magnetic resonance techniques to determine the dynamic structure of mitochondrial outer membrane proteins and their complexes;2011-11-01;2017-10-31;;Membrane proteins are coded by about 30% of the genes in the human genome and are primary targets for the action of drugs. I propose an interdisciplinary approach that will provide insight into the dynamic structure of membrane proteins of the outer mitochondrial membrane at unprecedented detail with respect to spatial resolution and time scale separation. Analysis of the dynamics and structure of membrane proteins is one of the biggest challenges in structural biology. I propose several new techniques mainly for solution NMR spectroscopy but also for solid-state NMR and electron paramagnetic resonance that go far beyond the state of art and enrich the sparse information from each of the individual techniques. The integration of complementary experimental information together with molecular dynamics simulations will push the description of the dynamic structure of membrane proteins to a new level. This new level is characterized by the possibility to determine structural ensembles of higher structural complexity and by access to dynamic time scales ranging from picoseconds to milliseconds. The characterization of motion is expected to establish the essential link between structure and function. The chosen outer mitochondrial membrane proteins are linked to several human pathologies that cannot be treated because structural and dynamic information at atomic resolution is missing. I expect that the novel insight into the dynamic structure of mitochondrial proteins will be critical to lay the basis for the development of novel, selective and improved therapies for cancer and age-related neurodegeneration.;1496200;1496200;ERC-2011-StG_20101109;/ERC-SG;DEUTSCHES ZENTRUM FUR NEURODEGENERATIVE ERKRANKUNGEN EV;DE;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;DE;"/BIO;/LIF";1;0;0;1;0;0 92069;235711;SMART;ONG;FP7-PEOPLE;FP7-PEOPLE-ITN-2008;FP7;Small Artery Remodelling;2009-10-01;2013-09-30;;Cardiovascular diseases are the leading cause of death and disability in the European population and represent a great burden of suffering and costs. Their complex etiology originates from different pathological stimuli and involves different cell types, resident in the vascular wall or infiltrating from the blood. The adaptation of the vasculature to physiological and pathophysiological forces depends on both the communication between its cellular components and their interaction with the extracellular matrix (ECM). When subjected to enhanced stretch, cyclic mechanical strain, or shear stress, blood vessels undergo typical transformations in wall shape that are always associated with alterations of the ECM and cellular composition, collectively described as vascular remodelling. Remodelling processes occur specifically in small arteries and arterioles, which show extreme changes in their size and function (microvascular remodelling). This is especially the case in hypertensive or diabetic patients, and contributes to a vicious cycle resulting in organ dysfunction and progression of vascular disease. A multidisciplinary approach is required to better understand vascular remodelling processes. We propose an interdisciplinary ITN to promote excellence in vascular biology, with focus on small vessels/arteries and their ECM. This will enhance the interaction between 8 academic groups and one SME in 7 European countries, specialized in physiology, signalling mechanisms, cell-cell and cell-matrix interactions in vascular endothelium and smooth muscle, as well as in drug discovery and development. The ITN will provide a specialized training ground by connecting investigations of the biology of vascular cells and their surrounding ECM in an innovative manner. It will therefore promote the careers of young investigators by specialising them in a field of vascular biology with a great potential for the future.;3096503;3096503;FP7-PEOPLE-ITN-2008;/MC-ITN;LUNDS UNIVERSITET;SE;"AARHUS UNIVERSITET;LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN;UNIVERSITAETSKLINIKUM HEIDELBERG;WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER;Academisch Medisch Centrum bij de Universiteit van Amsterdam;UNIVERSITE DE FRIBOURG;FONDATION DU CENTRE PLURIDISCIPLINAIRE D'ONCOLOGIE;KING'S COLLEGE LONDON;PECSI TUDOMANYEGYETEM - UNIVERSITY OF PECS;NEUROSEARCH AS";"DK;DE;NL;CH;UK;HU";"/SCI;/EDU";1;0;0;1;0;0 109585;607842;FINON;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-ITN;FP7;Female Investigators in Nonlinear Optical Nanoscopy - FINON;2013-10-01;2017-09-30;;The aim of this ITN is to take the category of Nonlinear Optical Microscopy (NOM) techniques into the nano-dimension, allowing for label-free three-dimensional (3D), dynamic imaging of macromolecular arrangements and nanostructures by probing inherent higher-order electronic and molecular vibrations with novel detection concepts. Specific S&T objectives are to (A) explore the use of nano-sized scanning probes, polarization or phase resolved detection schemes to enable nano-scale imaging, (B) benchmark their capabilities by fundamental studies and computations of molecular suprastructures and metallic nanostructures, and to (C) apply them in live-cell and fuel cell studies in order to introduce them as attractive instruments for the pharmaceutical-, nanotechnology-, and biosciences/industry. In particular, we will study (i) the formation of hierarchical structures of beta-amyloid, (ii) nonlinear emission by metallic nanoparticles/holes/antennas as potential nano-photonic devises, (iii) stem cell differentiation and metabolic expression in a 3D tissue model for drug screening and (iv) physic-chemical processes in fuel cell membranes. This sets requirements on a highly interdisciplinary and intersectoral working process. Consequently, the FINON ITN constitutes of partners from, and active interaction between, a wide range of disciplines spanning from front-line technology developers of laser instrumentation, microscopy, and nanophotonics to users of microscopy with extended experience and challenging requirements within the life-, chemical-, pharmaceutical- and material sciences. This forms an attractive training environment, with particular emphasis on early-stage and experienced researchers, offering unique networking opportunities and a vast variety of career paths.;3470652,02;3470652,02;FP7-PEOPLE-2013-ITN;/MC-ITN;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;DE;"ASTRAZENECA AB;ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;CARDIFF UNIVERSITY;CHALMERS TEKNISKA HOEGSKOLA AB";"SE;CH;FR;UK";/LIF;1;0;0;1;0;0 99901;293847;GLYCOPROTEOMICS;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-CIG;FP7;Quantitative Glycomics and Glycoproteomics for Biomarker Discovery;2011-08-01;2015-07-31;;"In the proposed project new, integrated technologies for quantitative and high throughput glycomics, glycoproteomics and the related bioinformatics will be developed. Glycoproteins are important cell-cell communication molecules: primarily located on the membrane, glycoproteins mediate inter-cell interaction, while secreted glycoproteins can distribute throughout the whole organism via the bloodstream. The structures of the glycans attached to these glycoproteins are known to change in response to disease. With more than 50% of all human proteins being predicted to be glycosylated, there is a dearth of reproducible and quantitative analytical technologies to determine the extensive micro- and macro-heterogeneity of these molecules. In this proposal, we aim to develop novel interdisciplinary approaches to provide hitherto unknown, accurate and detailed information on the identity and quantity of glycoproteins, AND their glycosylation, simultaneously and in a high throughput manner. The lack of any template or prediction tools that allow deduction of this information makes it crucial to develop new technologies in this area. This capacity will enable the acquisition of in-depth knowledge of protein glycosylation and the investigation of the biological role of these molecules in the context of Inflammatory Bowel Diseases (IBD) such as ulcerative colitis and Crohn’s disease. The prevalence of IBD has risen in the past 10 years with every fifth IBD patient being a child or adolescent. In Germany alone more than 300 000 patients suffer from IBD. To date a cure of IBD is still not possible and IBD are suspected to increase the risk of developing colorectal cancer, which itself is already the third most common cancer in developed countries. The findings produced by this study will provide the first steps for understanding IBD onset and improving diagnostic tests and treatments.";100000;100000;FP7-PEOPLE-2011-CIG;/MC-CIG;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;DE;;;/SCI;1;0;0;1;0;0 107830;327581;PHOTOSTM;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IOF;FP7;Investigating Photo Catalytic Reactions at the Molecular Scale;2013-06-01;2016-05-31;;"Understanding the mechanism of photo catalytic reactions is a key to systematically improve their efficiency and therewith enhance substantially the impact of green chemistry. Photo catalytic reactions are determined by the electronic level alignment between a catalyst and the reactant. This energy level alignment depends strongly on the local morphology of the catalyst and the absorption site of the reactant but is only poorly understood due to the difficulty to study photo catalytic reactions at the molecular length scale – the critical length scale for photo-catalytic processes. This project focuses on understanding the local electronic structure of catalyst and adsorbed reactant spectroscopically with molecular scale resolution and compare it to the local photo catalytic reactivity using state of the art Near Field Optical Microscopy and Ultra High Vacuum and Low Temperature Scanning Tunneling Microscopy. Semiconducting iron oxide nano wires will be studied as catalyst since this system is specifically promising for photo catalysis in combination with molybdenum hexa carbonyl as reactant model system. This challenging work will be realized by leveraging the unique expertise in surface catalytic reactions and nano scale electronic structure characterization at the Lawrence Berkeley National Laboratory and the Max Planck Institute for Nanoscale Science in Stuttgart respectively. The fast paste, inspiring and highly interdisciplinary environment at both institutions together with their career development programs for PostDoctoral fellows, and the challenging aspect of combining the expertise from varies fields to succeed with the proposed project will inevitably allow the applicant to develop as an independent and emerging researcher in the field of photo catalysis, creating the base for a highly successful scientific career.";252742,2;252742,2;FP7-PEOPLE-2012-IOF;/MC-IOF;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;DE;;;/LIF;1;0;0;1;0;0 88855;212236;POPP;ONG;FP7-ENVIRONMENT;ENV.2007.4.2.3.1.;FP7;Policies to promote sustainable consumption patterns (POPP);2008-08-01;2011-07-31;;"The project aims at increasing knowledge about the impact of sustainable consumption (SC) policies on consumption patterns and on sustainability. This objective will be achieved by the following steps: A conceptual model will be developed as a framework for the whole project. Embedded in a broader overview of general SC strategies and instruments, research will focus on the need areas of food and housing. For these areas, sustainability potentials will be quantified in order to identify the potential that SC policies may tap. Impacts will then be explored at macro and micro-level that food and housing related SC instruments throughout Europe have on consumption patterns (Impact Assessment). Instruments to be looked at encompass regulatory and economic instruments, including fiscal and procurement policies, as well as communicative instruments, procedural regulation and societal self-regulation. Conditions of success and failure of these instruments will be identified. The instrument impact assessment is based on the analysis of statistical data, expert interviews, focus groups with consumers and workshops with public procurers. Having explored the impact of SC instruments on consumption patterns, a material flow analysis will be carried out to assess their impact on sustainability, including at international level. Options to enhance sustainable consumption patterns will be explored, especially with regard to designing, implementing and transferring effective SC instruments. On the basis of the project results, policy recommendations will be developed to be fed into the Marrakech process. The project is relevant to the Work Programme by identifying the impact of different types of policy instruments at disaggregated level; by evaluating the conditions of success and failure of SC strategies in an interdisciplinary effort; by developing links between the economy, environment and society and presenting innovative policies to make consumption more sustainable.";1847815;1437078;FP7-ENV-2007-1;/CP-FP;OEKO-INSTITUT E.V. - INSTITUT FUER ANGEWANDTE OEKOLOGIE;DE;"KULUTTAJATUTKIMUSKESKUS;ASSOCIACIO ECOINSTITUT D'ECOLOGIA APLICADA;INSTITUT FUR SOZIAL OKOLOGISCHE FORSCHUNG GMBH;BALTIJAS VIDES FORUMS;ICLEI EUROPEAN SECRETARIAT GMBH (ICLEI EUROPASEKRETARIAT GMBH)*;UNIVERSITY COLLEGE LONDON";"FI;ES;DE;LV;UK";"/ECO;/ENV;/POL";1;0;0;1;0;0 92707;238176;NUCLEOSOME4D;ONG;FP7-PEOPLE;FP7-PEOPLE-ITN-2008;FP7;Nucleosome Structure & Function across Biological Scales and Biological Function;2009-11-01;2013-10-31;;"Chromatin packages a few meters of DNA into a nucleus measuring a few microns. This tight folding occurs by assembling DNA with histones into so-called nucleosomes, thus ensuring the mechanical stability of our genome. On the flipside, this makes nucleosomes a formidable obstacle to the machines that read, copy or repair its DNA message. One of the fundamental questions in biology is to understand how nucleosome structure is established, maintained and manipulated. Our Marie Curie Initial Training Network will carry out multidisciplinary, collaborative research projects focused on deciphering nucleosome structure and function in space and time (Nucleosome4D). Our main objective is to provide our young researchers with world-class research & training in nucleosome biology. We will use cutting-edge, interdisciplinary methods and collaborative projects to determine how nucleosomes are remodeled during transcription, when genes are silenced, as cell divide, as stem cells differentiate, during organismal development and in human disease. We utilize state-of-the-art approaches in structural biology, biophysics, cell biology, live-cell imaging, biochemistry, genetics, genomics and bioinformatics. We will implement a comprehensive training plan for scientific and career development using the best local approaches to research & training, by promoting exchanges, using the advise of our industrial partners and three Visiting Scientists, by sharing reagents and expertise, as well as through a structured set of scientific workshops and complementary skills training courses. Together, our effort will ensure the multidisciplinary and intersectorial training of a new cohort of young European researchers. This will allow our trainees to take the opportunities and meet the challenges of a successful career in the life science sector through excellent training, effective communication, great teamwork and proven project management skills.";4609511;4609511;FP7-PEOPLE-ITN-2008;/MC-ITN;LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN;DE;"FUNDACION CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III;HMGBiotech s.r.l.;Novartis Forschungsstiftung;EUROPEAN MOLECULAR BIOLOGY LABORATORY;UNIVERSITY OF DUNDEE;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;KOBENHAVNS UNIVERSITET;MEDIZINISCHE UNIVERSITAT INNSBRUCK;CENTRE EUROPEEN DE RECHERCHE EN BIOLOGIE ET MEDECINE;INSTITUT CURIE;JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN;Cambridge Cell Networks Ltd;THE HEBREW UNIVERSITY OF JERUSALEM;MEDICAL RESEARCH COUNCIL;SZEGEDI TUDOMANYEGYETEM;UNIVERSITETET I BERGEN";"ES;IT;CH;DE;UK;DK;AT;FR;IL;HU;NO";"/SCI;/EDU";1;0;0;1;0;0 108982;329700;HumanRib;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IEF;FP7;HumanRib: metal ion binding - stucture - function relations of the human CPEB3 ribozyme;2013-10-01;2015-03-31;;"Until recently, ribozymes (enzymes composed of folded RNA) were found only in lower organisms. The discovery of the human CPEB3 ribozyme, related to the Hepatitis Delta Virus one, was an enormous breakthrough, which gave rise to numerous scientific questions. In the scope of this project, I want to answer the most emerging ones; I aim to solve the NMR structure of the whole CPEB3 ribozyme (we already have some promising preliminary results), as well as to crystallize it (in collaboration with another group) and compare the solution NMR and solid state X-ray structure. To understand changes in dynamics and folding of the ribozyme in the presence of Mg(II) (the natural cofactor), and also in the presence of other metal ions, single-molecule FRET (Förster Resonance Energy Transfer) experiments will be performed. As a long–term goal (after the repatriation to my home University), I will use NMR to characterize specific metal binding sites, structural and thermodynamic changes within the ribozyme upon the addition of metal ions. A big advantage of this project is that the ribozyme will be studied as a whole unit and not cut down into smaller parts. Although much more challenging, this will give a complete and clear view on the metal ion binding - structure - function relations. I am convinced that the proposed interdisciplinary project, which combines structural biology with coordination chemistry, is an exciting and necessary field of study, crucial for understanding not only the complicated structure and pathway of metal – mediated cleavage of the only known human ribozyme, but also for providing insight into its evolutional background, after being compared to the mechanism in which the viral HDV ribozyme functions.";144466,65;144466,65;FP7-PEOPLE-2012-IEF;/MC-IEF;UNIVERSITAT ZURICH;CH;;;/SCI;1;0;0;1;0;0 87359;221661;NONLIN;ONG;FP7-PEOPLE;PEOPLE-2007-2-1.IEF;FP7;Nonlinear Pricing in Vertically Related Industries;2008-06-01;2010-05-31;;Instances of nonlinear pricing in vertical industries typically involves discount schemes where higher volume purchases or those that involve a larger selection of the supplier’s products lead to lower prices. Some of these discount schemes can generate incentive effects that are often associated with exclusive dealing. In absence of efficiency rationale these are often seen as potential mechanisms to exclude competitors and therefore carry a negative connotation in competition law. Disentangling the underlying motivations for loyalty discount schemes is essential for the capability of competition policy enforcement to separate anticompetitive instances from benign ones. This project aims to generate output that serves this end. Its benefits are likely to diffuse into competition law and policymaking. The applicant has received her PhD at Universitat Autonoma de Barcelona, and holds an assistant professorship at the University of Alicante. She conducts research on industrial economics, and is a dynamic researcher with numerous achievements. To accomplish the project the applicant would spend two academic years in the Economics Department at University College London, a research department in economics. UCL has vast scientific expertise and facilities required for conducting top quality academic research. In addition, its active involvement in interdisciplinary collaborations is valuable for this project. The proposal would contribute to applicant’s academic career. It would help improve her analytical skills and research training, diversify her knowledge, deepen her project management skills, create opportunities for long-lasting collaborations and get in touch with timely antitrust issues. Through the accomplishment of this project, the applicant aims to build a sound publication record, to make relevant research contributions, to advance knowledge, and to achieve professional independence.;170142,1;170142,1;FP7-PEOPLE-2007-2-1-IEF;/MC-IEF;UNIVERSITY COLLEGE LONDON;UK;;;"/SCI;/EDU";1;0;0;1;0;0 108328;319278;UQUAM;ONG;FP7-IDEAS-ERC;ERC-2012-SyG;FP7;Ultracold Quantum Matter;2013-07-01;2019-06-30;http://www.uquam.eu;"Quantum mechanics is the basis of our understanding of the microscopic world. It is also central to the collective behaviour of matter at low temperatures, leading to unique properties that defy our classical intuition. The comprehension of such ‘quantum matter’ and the ability to master it using a newly developing set of ‘quantum technologies’ is not only of fundamental interest but holds the promise of revolutionizing material and information science as well as metrology. Our aim is to take this interdisciplinary research field to a qualitatively new level, by taking advantage of the most recent spectacular advances in the control of ultracold atomic and molecular systems. To this end, we have gathered a team of PIs with well-recognized and complementary expertise in the domains of quantum optics, atomic and condensed matter physics, and information science. Our project is structured around three grand challenges: (i) Produce, understand and classify novel states of matter, including strongly correlated and topological quantum phases, and establish connections with simulation of field theories; (ii) Explore novel aspects of many-body dynamics, identify its universal regimes, and implement new classes of dissipative evolution; (iii) Engineer quantum matter to propose and implement new paradigms for information processing. We believe that only a joint effort, combining experimental tools beyond the state-of-the-art and novel theoretical approaches, will allow us to reach these outstanding goals. An essential element of the project, which will embody the synergy between the different perspectives brought by the PIs, will be the joint construction of an experiment employing transformative technologies. Our overall research program will allow us to address key questions on the nature of quantum matter and its potential high impact applications.";9827280;9827280;ERC-2012-SyG;/ERC-SyG;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;DE;"WEIZMANN INSTITUTE OF SCIENCE;THE REGENTS OF THE UNIVERSITY OF CALIFORNIA;UNIVERSITAET INNSBRUCK;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS";"IL;US;AT;FR";/SCI;1;0;0;1;0;0 100917;276217;Dynein Coordination;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-IIF;FP7;Mechanical basis for motor protein coordination in axenomes leading to the beating of cilia and flagella;2011-11-01;2013-10-31;;Cilia and flagella are highly conserved cell organelles that exhibit regular, serpentine beating motions. Each cilium and flagellum contains a motile organelle called an axoneme, which is comprised of an array of microtubules, dynein motor proteins, and accessory proteins. Recent studies have led to the hypothesis that intrinsic mechanical and mechanochemical properties of the dyneins provide the feedback and coordination necessary for the regular beating pattern of cilia and flagella. The objective of this project is to test this mechanical coordination hypothesis. The proposal takes an interdisciplinary approach, bringing together experiments and theory and using analytical tools from informatics, biochemistry, biomechanics, and mechanical engineering. Specifically, the proposal aims to measure the motor properties of individual molecules and small ensembles of dyneins using optical tweezers. These measurements will be used to evaluate the state of the art models of axoneme beating, confirming or rejecting the dynein coordination hypotheses on which they are based. The measured motor properties of dynein will be used to build a new model of the axoneme from the “bottom-up.” The principle advantage of this model over the existing models is that, rather than showing that a set of theoretical molecular properties can fit experimental data on whole flagella, it will specifically account for the measured molecular details of the axoneme. The ability of the “bottom up” model to predict experimentally acquired flagellar beat patterns will be compared to models from the literature. This project will be part of an increasing number of studies on the role mechanics and forces have on biology at the cell level. It will not only further our understanding of dynein coordination and flagellar motion, but also biological coordination in general, a phenomenon that has allowed for the evolution of complex organisms, but has remained largely unexplained.;225945;225945;FP7-PEOPLE-2010-IIF;/MC-IIF;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;DE;;;"/SOC;/COO";1;0;0;1;0;0 105536;317079;NANOMEM;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-ITN;FP7;Membrane Protein Nanocrystallography;2013-01-01;2016-12-31;;"Modern structural biology builds upon synergies between lab-bench scale science on the one hand and large scale research infrastructure on the other. NanoMem recognises the transformative opportunities that are created by current X-ray source and detector developments to impact strongly on membrane protein structure, a challenging sub-field of structural biology. We will exploit synchrotron based micro-focus X-ray beams to address challenging diffraction studies from small membrane protein crystals; and embrace the revolutionary possibilities created by X-ray Free Electron Lasers to deliver an entirely new regime of high-resolution serial femtosecond crystallography of membrane proteins. These developments will place heavy demands on motivated and highly-trained talent. The time is ripe for bringing young scientists into the loop. Nanomem will train the nucleus of a new community spread across Europe that widens the access and use of non-conventional methods to capture membrane protein structures at high resolution. Our interdisciplinary and intersectorial research training work programme incorporates membrane protein production, purification and crystallisation, micro and nano-crystal manipulation, micro-focus diffraction at synchrotron sources, nano-focus diffraction at X-ray free electron lasers, serial femtosecond crystallography, software development, drug design, and commercialisation of the most helpful innovations. On-site scientific training of nine ESRs and one ER with seamless industrial participation will be complemented with training in areas such as intellectual property, communication skills and scientific mentoring. The current major European effort in the construction of new brilliant X-ray sources has to be matched by an investment in nurturing the birth of a scientific community for its exploitation, pushing the limits of our understanding of membrane protein structural biology.";2814628,53;2814628,53;FP7-PEOPLE-2012-ITN;/MC-ITN;GOETEBORGS UNIVERSITET;SE;"IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE;MOLECULAR DIMENSIONS LIMITED;UNIVERSITAET HAMBURG;EUROPEAN SYNCHROTRON RADIATION FACILITY;ASTRAZENECA AB;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;PAUL SCHERRER INSTITUT;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;SWISSCI AG";"UK;DE;FR;SE;CH";/LIF;1;0;0;1;0;0 107340;329908;OFB-SCI;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IEF;FP7;Orthogonally Functionalized Binary Nanopatterned Polymeric Substrates for T cell activation and proliferation in Cancer Immunotherapy;2013-04-01;2015-03-31;;'Harnessing the power of the immune system to fight malignancies remains a challenging goal although important progress has recently been achieved. For example, cancer remission of terminal leukemia patients was accomplished with genetically modified autologous T cells (Dr. June, University of Pennsylvania, 2011). However, these adoptive T cell therapies are limited by the availability of target specific T cells that are extracted from each patient, expanded ex vivo, and transferred back to the patient. To extend cancer immunotherapies to clinics, the current T cell expansion technologies need to be improved to efficiently produce the large amounts of T cells that are required. To overcome this problem we propose the development of orthogonally functionalized binary nanopatterned polymeric substrates that will act as efficient artificial ‘T cell proliferation machines’. These binary nanopatterns will consist of gold and oxide nanoparticles that will be orthogonally functionalized with either anti-CD3 or anti-CD28, which are the biomolecules that trigger T cells and activate their expansion. These substrates will introduce an unprecedented fine control in the nanoscale that will certainly contribute to the understanding of the immune processes that remain enigmatic in spite of their fundamental role in the survival of species. The OFB-SCI project proposes a truly multidisciplinary and intersectorial research in the field of Cancer Nanotechnology with a clear ambition to transfer the knowledge acquired to the industry in the near-future facilitating the introduction of novel cancer immunotherapies in clinics. Overall, this project will offer a first class training experience to a promising young European researcher, Dr. Guasch, based on a broad and challenging yet feasible program carefully embedded in a genuine interdisciplinary environment such as Prof. Spatz’s group at the Max Planck Institute for Intelligent Systems and the University of Heidelberg (Germany).';161968,8;161968,8;FP7-PEOPLE-2012-IEF;/MC-IEF;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;DE;;;/SCI;1;0;0;1;0;0 100140;293567;SOLAR-PLUS;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-CIG;FP7;Maximizing the Efficiency of Luminescent Solar Concentrators by Implanting Resonant Plasmonic Nanostructures (SOLAR-PLUS);2011-09-01;2015-12-01;;Maximizing the Efficiency of Luminescent SOLAR Concentrators by Implanting Resonant PLASmonic Nanostructures(SOLAR-PLUS) is a four-year interdisciplinary research project in optical electromagnetic modeling, material engineering and nanotechnology fabrication, whose aim is to reduce the cost of harvesting solar energy by exploiting advanced nanophotonic concepts. The main technical objective of the proposed work is to double the energy conversion efficiency of a typical monolayer luminescent solar concentrator (LSC) system, currently standing at <4% to >8%, by harnessing the interplay phenomena between fluorescence and localized surface Plasmon resonances. The deliverables of the project are: i) To understand the fundamental interactions between plasmonics and fluorescent molecules and through the gained physical insight to derive a set of design rules for metallic nanoparticles tailored to LSC applications, ii) to develop a generic simulation platform that combines nanoscale and macroscale modeling, to allow for rapid prototype performance assessment before proceeding to expensive fabrication, iii) to fabricate highly efficient prototype plasmonic-LSCs and, iv) to explore completely new research avenues that can bring about radical improvements to LSC efficiency. Improving the energy conversion efficiency of LSCs and reducing their cost are important steps towards the commercial viability of this technology, which will assist in the EUs efforts to limit its dependence on fosil fuels. In addition, the project will serve to ensure the long term professional stability of the fellow by assisting him in securing a permanent position in the department of Electrical and Electronic Engineering at University College London.;100000;100000;FP7-PEOPLE-2011-CIG;/MC-CIG;UNIVERSITY COLLEGE LONDON;UK;;;/SCI;1;0;0;1;0;0 88976;212749;GGP;ONG;FP7-INFRASTRUCTURES;INFRA-2007-2.1-01;FP7;Generations and Gender Programme: A European Research Infrastructure on the Causes and Consequences of Demographic Developments;2009-01-01;2013-03-31;;The proposed project aims at improving the ability of the social sciences to explain the causes and consequences of demographic developments, and in particular of the changing relationships between genders and generations, in a manner that would allow working out sustainable responses to policy challenges. The project develops an infrastructure that provides for a breakthrough towards better understanding of the forces that lie behind demographic developments by integrated analyses of the micro-level demographic choices of individuals and households and the various contexts in which they act. It develops and refines a multi-disciplinary population survey and a macro-level contextual database that cover the wide range of topics relevant for explaining demographic trends and behaviour, as well as their consequences. The project integrates the approaches from different disciplinary perspectives, such as demography, sociology, economics, political science, statistics, survey methodology, psychology and social psychology, and epidemiology. The work mainly builds on the platform of the Generations and Gender Programme (GGP), including the Generations and Gender Survey and the GGP contextual database. The resulting European research infrastructure will provide a standardized and comparative approach to interdisciplinary analyses of demographic phenomena, which covers the wide range of different European societies, is oriented towards the needs of policy-making and relies on up-to-date data sources designed to meet these analytic needs.;2489617,6;2000000;FP7-INFRASTRUCTURES-2007-1;/CP;KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW;NL;"HUNGARIAN CENTRAL STATISTICAL OFFICE DEMOGRAPHIC RESEARCH INSTITUTE;INSTITUT NATIONAL D'ETUDES DEMOGRAPHIQUES;UNIVERSITA COMMERCIALE LUIGI BOCCONI;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;OSLOMET - STORBYUNIVERSITETET;STATISTISK SENTRALBYRAA;UNIVERSITY OF YORK;NORSK INSTITTUT FOR FORSKNING OM OP PVEKST VELFERD OG ALDRING;ERASMUS UNIVERSITEIT ROTTERDAM;UNIVERSITEIT UTRECHT;UNIVERZA V LJUBLJANI";"HU;FR;IT;DE;NO;UK;NL;SI";"/SCI;/MED";1;0;0;1;0;0 92798;240853;HSSLU;ONG;FP7-IDEAS-ERC;ERC-SG-ID1;FP7;Human Sociality and Systems of Language Use;2010-01-01;2014-12-31;;Informal conversation is the primary context for all central processes of language. Yet it is the least studied. The many advances of traditional linguistic typology the systematic comparison of the world s languages have been based on 'isolated sentences' as data. This project will meet the challenge of working with rich conversational data. This stands to permanently remedy our skewed linguistic understanding by pioneering a systematic approach to the comparison of *language use*, to complement the comparison of language structure. This not only forges a new field of comparative linguistics, it opens up new questions of language and mind. Within mind , we include the high-order social intelligence that defines being human: our human sociality . This project will use data from social interaction to show that language is a window onto the *social mind*. A team of 6 will work on 7 languages (English, and 2 languages of Asia, Africa, and S. America), toward 3 project objectives. Objective 1 is collection of corpora of video-recorded conversation in the field. Objective 2, drawing on these corpora, is a systematic description of three defined systems in each language: (1) *repair* (of problems in speaking and understanding), (2) *reference*, and (3) *requests* (using language to get others to do things). Each system provides a window onto core aspects of human sociality: The project will focus on the relation between informational imperatives (common knowledge and perspectives) and affiliational imperatives (matters of face and social manipulation). Objective 3, drawing on Objective 2, is a detailed coding and quantitative comparison of the 3 systems across the 7 languages. This systematic comparison of systems of language use will do two things: 1. set the agenda for a new tradition in linguistics a *typology of language use* and 2. bring new evidence to bear upon interdisciplinary questions of the nature and cultural variability of human sociality.;1999800;1999800;ERC-2009-StG;/ERC-SG;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;DE;;;/SCI;1;0;0;1;0;0 91025;226248;ATP;ONG;FP7-ENVIRONMENT;ENV.2008.1.1.5.2.;FP7;Arctic Tipping Points;2009-02-01;2012-01-31;;The broad interdisciplinary consortia assembled in the Arctic Tipping Points (ATP) project will be managed (WP1) to identify the elements of the Arctic marine ecosystem likely to show abrupt changes in response to climate change, and establish the levels of the corresponding climate drivers inducing the regime shift for these tipping elements. ATP will evaluate the consequences of crossing those tipping points, and the associated risks and opportunities for economic activities dependent on the Arctic marine ecosystem. Historical records of Arctic climate change and projections of future changes in Arctic sea climate and ice systems are compiled (WP2), and time series of Arctic ecosystem components analysed using novel statistical tools to detect regime shifts and ecological thresholds and tipping points, and evaluate their sensitivity to climatic forcing (WP3). Experimental manipulations and comparative analyses across broad climatic ranges will be used to detect climatic thresholds and tipping points of Arctic organisms and ecosystems, using genome-wide analyses to develop genomic markers of climate-driven stress useful as early-warning indicators of the proximity of tipping points (WP4). A biological-physical coupled 3 D model will be used to generate future trajectories of Arctic ecosystems under projected climate change scenarios and to identify their consequences for the Arctic ecosystem (WP5). The impacts of abrupt changes in the Arctic ecosystems for activities of strategic importance for the European Arctic and the associated impacts on employment and income will be elucidated, and policies and legislative frameworks to adapt and mitigate these impacts will be analysed (WP 6). The effectiveness of possible alternative, post-Kyoto policies and stabilization targets in avoiding climate-driven thresholds in the Arctic ecosystem will be examined, and the results and projections will be conveyed to policy makers, economic sectors and the public in general (WP7).;6545776,09;4998098,1;FP7-ENV-2008-1;/CP-IP;UNIVERSITETET I TROMSOE;NO;"AARHUS UNIVERSITET;UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6;KUNGLIGA VETENSKAPSAKADEMIEN;THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;SINTEF FISKERI OG HAVBRUK AS;AKVAPLAN-NIVA AS;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS;INSTYTUT OCEANOLOGII POLSKIEJ AKADEMII NAUK;CENTRO DE CIENCIAS DO MAR DO ALGARVE;P.P. SHIRSHOV INSTITUTE OF OCEANOLOGY OF RUSSIAN ACADEMY OF SCIENCES;GRONLANDS NATURINSTITUT";"DK;FR;SE;UK;NO;DE;ES;PL;PT;RU;GL";/ENV;1;0;0;1;0;0 96905;264774;SYMBIOMICS;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-ITN;FP7;Symbiomics: Molecular Ecology and Evolution of Bacterial Symbionts;2011-01-01;2014-12-31;;Symbiosis research is currently in the midst of a revolution as molecular techniques are leading to major breakthroughs in our understanding of interactions between animals and microbes. There is an emerging recognition that all animals are intimately associated with a complex community of beneficial microbes that are essential for their development, nutrition, and health. Thus, modern symbiosis research has become a newly emerging supra-disciplinary field with novel and innovative methods for examining microbial symbionts, the vast majority of which remain as yet uncultivable. As so often when novel technologies open up new areas of research, training for students lags behind. We propose to close this gap by offering a comprehensive and innovative training in the microbial ecology and evolution of animal symbionts. The proposed ITN Symbiomics will include 14 leading research groups as well as 4 top-tier participants from the private sector to provide 14 early stage researchers (ESRs) and 1 experienced research (ER) with an interdisciplinary and synergistic training. Cutting edge methods in molecular biology and image analysis will be used to analyze a broad range of hosts from protozoan and invertebrate animal groups. Symbiomics will provide training through a combination of local and network-wide activities that will include research, secondments, workshops and courses including soft skills training, networking and meetings, regular thesis committee meetings, and mentoring. By pooling the scientific, technological, and entrepreneurial expertise of the Symbiomics partners, this ITN will provide a synergistic research environment and training that extends far beyond what each partner would be able to offer with local training alone. At the end of their training, the early stage researchers will have the skills they need for successful careers in academia and industry in a broad range of disciplines in the fields of environmental, applied, and medical microbiology.;3782465,5;3782465,5;FP7-PEOPLE-2010-ITN;/MC-ITN;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;DE;"AARHUS UNIVERSITET;UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6;Ribocon GmbH;UNIVERSITAT WIEN;UNIVERSITAT DE VALENCIA;UNIVERSITY OF NEWCASTLE UPON TYNE;UPPSALA UNIVERSITET;UNIVERSITAET GREIFSWALD";"DK;FR;DE;AT;ES;UK;SE";"/EDU;/NET";1;0;0;1;0;0 100128;265031;COHERENCE;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-ITN;FP7;Cooperativity in Highly Excited Rydberg Ensembles - Control and Entanglement;2011-09-01;2015-08-31;;"'The central goal of the 'COHERENCE' network is the training of Early Stage Researchers (ESRs) and Experienced Researchers (ERs) to the highest level of international excellence within the rapidly growing field of electronically highly excited (Rydberg) gases and aggregates. The systems range from single atoms to large mesoscopic ensembles with full control over motional and internal degrees of freedom. Recent scientific progress has primarily been made by a number of European experimental and theoretical groups which are all assembled within the network. The field of Rydberg gases is at the crossroads between various scientific areas, including condensed matter physics, biophysics, molecular physics, quantum optics and quantum information, surface science, plasma physics, and laser technology. As perspective applications of Rydberg systems are already in sight, two optics and laser development companies have joined the network delivering technological expertise and in-depth training in business matters. The elaborate and well-structured training programme includes a schedule of workshops, schools, and conferences. The training will be strongly focused on the individual researchers by assigning each of them an international Thesis Advisory Board and by designing Individual Career Development Plans. Based on the interdisciplinary character of the research, the training content will include a blend of broad scientific, technological, and complimentary skills providing excellent perspectives for successful careers in both academia and industry. ESRs will also profit from the extensive exchage programme among the participating teams based on cotutelles, short- and long-term secondments. The 'COHERENCE' network will thus ensure that Europe maintains the leading role within an important area of research and will stimulate transformation of the generated knowledge into new technologies.'";4570942;4570942;FP7-PEOPLE-2010-ITN;/MC-ITN;RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG;DE;"AARHUS UNIVERSITET;UNIVERSITY OF DURHAM;UNIVERSIDAD DE GRANADA;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;CONSIGLIO NAZIONALE DELLE RICERCHE;EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;UNIVERSITAET STUTTGART;UNIVERSITAET INNSBRUCK;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;TOPTICA PHOTONICS AG;UNIVERSITEIT VAN AMSTERDAM";"DK;UK;ES;DE;IT;CH;AT;FR;NL";"/EDU;/NET";1;0;0;1;0;0 109363;607585;OSNIRO;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-ITN;FP7;Organic Semiconductors for NIR Optoelectronics;2013-10-01;2017-09-30;;"Scientific targets of the planned project are synthesis, characterization and application of NIR absorbing and emitting organic materials for Organic Electronics. NIR sensitive absorbers show a great potential for the development of a new generation of printable photodetectors with tuneable sensitivity windows that may be integrated into multifunctional devices for chemical/biological sensing or optical communication. The novel devices may result in lower costs, and they could be used for the construction of large, flexible sensors. NIR emitting OLEDs also gained growing attention because of potential applications in information processing and night-vision readable displays. The consortium can look back to very promising exploratory work on the generation of novel NIR absorbing “low bandgap” copolymers and their application in organic solar cells of the bulk heterojunction type, bulk heterojunction-type organic solar cells containing “low bandgap” organic materials as sensitizing components and on NIR OLEDs based on “low bandgap” copolymers or oligomers. The consortium aims to train PhD students in this very interdisciplinary field (chemistry, physics, materials science) in a close and fruitful collaboration between academic institutions and industry. The consortium is well-placed around leading academic groups in materials science (please see: http://www.sciencewatch.com/dr/sci/misc/Top100MatSci2000-10/) and important industrial players/manufacturers (ADVENT, Siemens, NikkoIA) and will condition young European scientists for the needs of the next decades.";3631857,68;3631857,68;FP7-PEOPLE-2013-ITN;/MC-ITN;BERGISCHE UNIVERSITAET WUPPERTAL;DE;"FRIEDRICH-ALEXANDER-UNIVERSITAET ERLANGEN NUERNBERG;NIKKOIA SAS;ADVANCED ENERGY TECHNOLOGIES AE EREUNAS & ANAPTYXIS YLIKON & PROIONTONANANEOSIMON PIGON ENERGEIAS & SYNAFON SYMVOULEFTIKON Y PIRESION*ADVEN;SIEMENS HEALTHCARE GMBH;UNIVERSITY COLLEGE LONDON;TECHNISCHE UNIVERSITEIT EINDHOVEN;SIEMENS AKTIENGESELLSCHAFT;CHALMERS TEKNISKA HOEGSKOLA AB";"DE;FR;EL;UK;NL;SE";/LIF;1;0;0;1;0;0 92329;235502;OXICELLCYCLE;ONG;FP7-PEOPLE;FP7-PEOPLE-IEF-2008;FP7;Coordination of Oxidative Stress Signalling with Forkhead-Regulated Transcription during the Fission Yeast Cell Cycle;2009-10-01;2011-09-30;;Cellular proliferation and environmental factors in general, and cell cycle-regulated transcription and oxidative stress in particular, are of vital importance for aging and accompanying complex diseases. The overall goal of this project is to gain systems-level insight into the intriguing relationship between oxidative stress signalling and cell cycle regulation. Oxidative stress causes widespread cellular damage by increased concentrations of reactive oxygen species. Available data indicate that specific clusters of cell cycle-regulated genes, whose expression depends on members of the conserved forkhead family of transcription factors, are repressed during oxidative stress, and this repression then promotes cell survival. Using fission yeast as a powerful model system, we plan to use a wide range of genome-wide methodologies combined with genetics to elucidate two major questions regarding the connection between oxidative stress and cell cycle control: 1) how stress-activated signalling pathways regulate forkhead-mediated transcription, and 2) how repression of forkhead-mediated transcription in turn leads to oxidative damage protection. This project, which takes advantage of the use of a simple model organism and multiple high-throughput and integrative approaches, will promote a systems-level understanding of the complex interplay between cell cycle control and oxidative stress signalling. To get the most from the proposed research will require interdisciplinary interactions with colleagues both within the host laboratory and with outside experts. The proposed research should result in valuable fundamental information to help tackle aging-related diseases. Importantly, this fellowship would also provide a rich training opportunity, by diversifying research skills and promoting complementary competencies, which would be a crucial step for the motivated and talented candidate towards an independent research career.;;171867,63;FP7-PEOPLE-IEF-2008;/MC-IEF;UNIVERSITY COLLEGE LONDON;UK;;;"/SCI;/EMP";1;0;0;1;0;0 185905;623380;GW ASAP;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IOF;FP7;Gravitational Wave Astrophysics and Analysis with Pulsars;2014-07-14;2017-07-13;;"'Gravitational waves, ripples of space-time from accelerating masses, are the most elusive prediction of Einstein’s theory of General Relativity; So elusive in fact, that they have yet to be directly detected, although indirect evidence from binary pulsars (e.g. Taylor and Weisberg, 1982) supports their existence. This project implements new and novel techniques to search for direct evidence of gravitational waves from supermassive black holes using Pulsar Timing Arrays by means of a new interdisciplinary collaboration in radio and infrared astronomy, data analysis and astrophysics. I will lead an international team of experts to simulate an astrophysically motivated gravitational wave background using candidate supermassive black hole binaries from galaxy catalogues. We will then assess the expected level of anisotropy in the gravitational wave background and use this information as a prior in a new and novel data analysis project which implements anisotropy in GW search algorithms. Finally, we extend the anisotropic search method to gravitational waves from single sources using a new 'hybridized' technique which may prove to be an invaluable tool in the search for, and first detection of, gravitational waves.'";262975,2;262975,2;FP7-PEOPLE-2013-IOF;/MC-IOF;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;DE;;;/LIF;1;0;0;1;0;0 111184;602891;NEUROPAIN;ONG;FP7-HEALTH;HEALTH.2013.2.2.1-5;FP7;Neuropathic pain: biomarkers and druggable targets within the endogenous analgesia system;2014-01-01;2018-12-31;;Neuropathic pain has a high incidence in Europe and often affects the patient’s emotional balance and quality of life. Recent meta-analyses have shown that conventional analgesic drugs are not sufficiently effective in these patients and are limited by serious side effects. The search for new analgesics is extremely difficult despite identification of several new potential targets and enormous investment by the pharmaceutical industry. Important reasons for this failure are the poor predictive validity of currently available animal models of chronic pain, that do not simulate multidimensional clinical pain, and the high inter-individual variability of neuropathic pain manifestations and treatment responses. We will overcome these obstacles by an interdisciplinary collaboration between basic science groups, clinicians and leading private companies. This consortium will validate new animal models to evaluate the electrophysiological, behavioural, emotional and cognitive manifestations of neuropathic pain and the effectiveness of novel compounds. The use of these models in combination with other behavioural paradigms and new conditional knockout mouse lines for specific components of the endogenous opioid and cannabinoid system will permit the identification of novel druggable targets and biomarkers for neuropathic pain. Novel analgesic compounds acting on these endogenous systems developed by the private companies of the consortium will be tested in these new paradigms. Clinical studies will identify novel biomarkers for neuropathic pain using powerful genetics approaches and investigate treatment effectiveness with a translational focus based on cross validation of the findings in animals and humans.;8540388,46;5992577;FP7-HEALTH-2013-INNOVATION-1;/CP-FP;UNIVERSIDAD POMPEU FABRA;ES;"HELSINGIN JA UUDENMAAN SAIRAANHOITOPIIRIN KUNTAYHTYMÄ;IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE;UNIVERSITAETSKLINIKUM BONN;INSTYTUT FARMAKOLOGII POLSKIEJ AKADEMII NAUK;ISLENSK ERFDAGREINING EHF;GW PHARMA LIMITED;CENTRE EUROPEEN DE RECHERCHE EN BIOLOGIE ET MEDECINE;CHARITE - UNIVERSITAETSMEDIZIN BERLIN;UNIVERSITY COLLEGE LONDON;Laboratorios del Dr Esteve, SA";"FI;UK;DE;PL;IS;FR;ES";/LIF;1;0;0;1;0;0 106241;305522;COBRA;ONG;FP7-HEALTH;HEALTH.2012.2.3.2-2;FP7;Co-morbidity in relation to Aids;2013-03-01;2017-02-28;http://fp7-cobra.eu/;"Persons with HIV on combination antiretroviral therapy (cART) are at increased risk of the premature development of age-associated non-communicable comorbidities (AANCC), including cardiovascular, chronic kidney, liver and pulmonary disease, diabetes mellitus, osteoporosis, non-AIDS associated malignancies, and neurocognitive impairment. It has therefore been hypothesised that such individuals, despite effective cART, may be prone to accelerated ageing. The underlying pathogenesis is likely to be multifactorial and include sustained immune activation, both systemically and within the central nervous system. By building on an established infrastructure for conducting longitudinal HIV cohort studies in Amsterdam and London, we will provide a detailed, prospective evaluation of AANCC among HIV-infected patients suppressed on cART and appropriately chosen and comparable non-infected controls. In this way, we will provide a robust estimate of the effect of treated HIV infection on the prevalence, incidence and age of onset of AANCC, thus clearly establishing a link between HIV and AANCC. Through the “Human Immune System” (HIS) mouse model, experimental studies will permit us to differentiate the effects of HIV and cART on metabolic outcomes when applied under controlled conditions, thereby further elucidating the causative nature of the link between HIV and AANCC. To further clarify potential pathogenic mechanisms underlying this causative link, including the possible induction of an inflammation-associated accelerated ageing phenotype, biomarkers which reflect each of these mechanisms will be investigated in biomaterial obtained from HIS mice and humans, and subsequently validated in patients with HIV on cART. The successful execution of the experimental and clinical research outlined in this proposal will be ensured through a strong interdisciplinary collaboration between clinical, basic and translational scientists bridging the fields of HIV, AANCC and ageing.";7800514,21;5998758,1;FP7-HEALTH-2012-INNOVATION-1;/CP-FP;Academisch Medisch Centrum bij de Universiteit van Amsterdam;NL;"IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE;STICHTING KATHOLIEKE UNIVERSITEIT;GEMEENTE AMSTERDAM;VIB;ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA;UNIVERSITAT KONSTANZ;STICHTING HIV MONITORING;ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM;UNIVERSITY COLLEGE LONDON;UNIVERSITA DEGLI STUDI DI MODENA E REGGIO EMILIA;GOETEBORGS UNIVERSITET";"UK;NL;BE;IT;DE;SE";/SCI;1;0;0;1;0;0 185421;340077;RUN;ONG;FP7-IDEAS-ERC;ERC-AG-SH3;FP7;Rethinking Urban Nature;2014-05-01;2019-04-30;;This ground-breaking project will challenge existing understandings of urban nature using an innovative interdisciplinary framework in a comparative international context. The project provides a new theoretical approach that moves beyond existing approaches to provide a novel synthesis between advances in urban ecology and original insights into cultural and political dimensions to the production of urban space. My core hypothesis is that in order to understand the dynamics of urban nature we must link the independent agency of nature with a renewed urban environmental history that takes full account of changing conceptions of human subjectivity, the ideological dimensions to scientific metaphors, and the need to develop new critical engagements with the global South. Using four cities as case studies — London, Berlin, Tallinn, and Chennai — the project will show that a theoretically nuanced and historically grounded exploration of the intersections between critical urban discourses and recent advances in urban ecology provides a vital counterpoint to narrowly utilitarian approaches to urban nature. In addition to a series of academic outputs the project will also create a documentary film, an exhibition, a website, and a series of workshops and public events.;2384238;2384238;ERC-2013-ADG;/ERC-AG;THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;UK;UNIVERSITY COLLEGE LONDON;UK;"/REG;/ENV;/SOC";1;0;0;1;0;0 203704;115363;COMPACT;ONG;FP7-JTI;IMI-JU-04-2011-03;FP7;Collaboration on the Optimisation of Macromolecular Pharmaceutical Access to Cellular Targets;2012-11-01;2017-10-31;;Most biopharmaceuticals (BP) currently on the market are recombinant proteins which are parenterally administered. These would benefit from more patient-friendly routes of administration. Moreover, new classes of BP (e.g. siRNA, miRNA, DARPins) with specificity for intracellular targets hold promise but await the advent of efficient delivery systems before their potential can be realised into therapeutic products. Solving the bottleneck of BP delivery is one of the main incentives of the pharmaceutical industry as this would allow a broadening of the spectrum of potential targets for therapeutic intervention needed to fill their drug pipelines. COMPACT represents Europe’s frontrunners in pharmaceutics, nanotechnology, biology, chemistry, engineering and imaging who will work in close collaboration with EFPIA on the delivery issues with BP. The main objectives are (1) to identify and understand transport pathways across biological barriers and cell membranes that can be utilized for delivery of BP, (2) to construct, characterise and preclincally validate BP formulations for non-invasive delivery of BP, with an emphasis on oral, airway and (trans)dermal delivery and for transport over the BBB. This will be achieved by setting up sophisticated in vitro models of biological barriers and appropriate animal models to find pathways that can be used for effective delivery of BP. In parallel, we will alter the BP either by chemical or biological engineering or by nano-formulations to enhance their uptake or transport over biological barriers.To be able to follow the transport,advanced imaging techniques will be utilised. The unique feature of this consortium is the alliance of experts in different research fields that complement each other in this challenging task. It is only the concerted action of such an interdisciplinary consortium that can make a difference in finding constructive solutions to the problem of poor bioavailability and target accessibility of BP.;29983543;10184909;IMI-JU-04-2011;/JTI-CP-IMI;SANOFI-AVENTIS DEUTSCHLAND GMBH;DE;"PFIZER LIMITED;ABBVIE DEUTSCHLAND GMBH & CO KG;LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN;UNIVERSITEIT LEIDEN;HELSINGIN YLIOPISTO;GLAXOSMITHKLINE RESEARCH AND DEVELOPMENT LTD.;BIONEER A/S;UNIVERSITEIT GENT;UNIVERSITAT WIEN;KOBENHAVNS UNIVERSITET;UNIVERSITAT ZURICH;HELMHOLTZ-ZENTRUM FUER INFEKTIONSFORSCHUNG GMBH;BOEHRINGER INGELHEIM INTERNATIONALGMBH;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;UNIVERSITEIT UTRECHT;NOVO NORDISK A/S;PHARMACOIDEA FEJLESZTO ES SZOLGALTATO KFT.;NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU;CARDIFF UNIVERSITY;STOCKHOLMS UNIVERSITET;Merck KGaA";"UK;DE;NL;FI;DK;BE;AT;CH;HU;NO;SE";;1;0;0;1;0;0 97919;231126;LivingKnowledge;CLO;FP7-ICT;ICT-2007.8.6;FP7;LivingKnowledge – Facts, Opinions and Bias in Time;2009-02-01;2012-01-31;;Knowledge and its articulations are strongly influenced by diversity in, e.g., cultural backgrounds, schools of thought, geographical contexts. Judgements, assessments and opinions, which play a crucial role in many areas of democratic societies, including politics and economics, reflect this diversity in perspective and goals. For the information on the Web (including, e.g., news and blogs) diversity - implied by the ever increasing multitude of information providers - is the reason for diverging viewpoints and conflicts. Time and evolution add a further dimension making diversity an intrinsic and unavoidable property of knowledge.
The vision inspiring LivingKnowledge is to consider diversity an asset and to make it traceable, understandable and exploitable, with the goal to improve navigation and search in very large multimodal datasets (e.g., the Web itself). LivingKnowledge will study the effect of diversity and time on opinions and bias, a topic with high potential for social and economic exploitation. We envisage a future where search and navigation tools (e.g., search engines) will automatically classify and organize opinions and bias (about, e.g., global warming or the Olympic games in China) and, therefore, will produce more insightful, better organized, easier-to-understand output.
LivingKnowledge employs interdisciplinary competences from, e.g., philosophy of science, cognitive science, library science and semiotics. The proposed solution is based on the foundational notions of context and its ability to localize meaning, and the notion of facet, as from library science, and its ability to organize knowledge as a set of interoperable components (i.e., facets). The project will construct a very large testbed, integrating many years of Web history and value-added knowledge, state-of-the-art search technology and the results of the project. The testbed will be made available for experimentation, dissemination, and exploitation.;6204717;4809461;FP7-ICT-2007-3;/CP;UNIVERSITA DEGLI STUDI DI TRENTO;IT;"FUNDACIO BARCELONA MEDIA;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;SORA OGRIS & HOFINGER GMBH;STICHTING INTERNET MEMORY FOUNDATION;UNIVERSITA DEGLI STUDI DI PAVIA;Indian Statistical Institute;UNIVERSITY OF SOUTHAMPTON;CONSORZIO NAZIONALE INTERUNIVERSITARIO PER LE TELECOMUNICAZIONI;GOTTFRIED WILHELM LEIBNIZ UNIVERSITAET HANNOVER";"ES;DE;AT;NL;IT;IN;UK";"/ELM;/IPS;/SOC;/TEL";1;0;0;1;0;0 86704;211601;ELIXIR;ONG;FP7-INFRASTRUCTURES;INFRA-2007-2.2-01;FP7;European Life-science Infrastructure for Biological Information;2007-11-01;2012-12-31;;"The objective of the ELIXIR preparatory phase is to produce a memorandum or memoranda of understanding between organisations (government agencies, research councils, funding bodies and scientific organisations) within the member states, with the purpose of constructing a world class and globally positioned European infrastructure for the management and integration of information in the life sciences. To achieve this, we will address the following tasks and issues: 1 Define the scope of the infrastructure, its role and benefits 2 Define an appropriate governance and legal structure 3 Define a long term funding structure to provide a sustainable infrastructure 4 Define the requirements for the European Data Centre in the next 5-10 years and makes plans to meet these needs 5 Involve all relevant stakeholders, including users, data providers, tools providers to ensure that the infrastructure meets their needs 6 Explore integration and interoperability between core and specialised data resources and the development of standards in newly emerging fields 7 Define the critical interdisciplinary links that need to be forged between the ‘biological’ and related scientific disciplines, including medicine, agriculture and the environment 8 Define the needs of related European industries 9 Define a training strategy to ensure that Europe effectively exploits all the available information The specific activities of the preparatory phase will include: A Holding stakeholder meetings to bring together national representatives, key scientific opinion and funding organisations. B Establishing working parties, supported by technical feasibility studies where appropriate, to address the tasks and issues above with final reports at month 18. C Consolidating these reports into a management and funding proposal to be sent to member states and funding agencies with draft MoU by month 38 and to seek agreement on the MoU and establish an Interim ELIXIR Board by month 50. D To establish the detailed organization of ELIXIR; and to draft and work toward the signing of the ELIXIR International Consortium Agreement";5868924,92;4500000;FP7-INFRASTRUCTURES-2007-1;/CP-CSA-Infra;EUROPEAN MOLECULAR BIOLOGY LABORATORY;DE;"FUNDACION CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III;NEDERLANDSE ORGANISATIE VOOR WETENSCHAPPELIJK ONDERZOEK;INSTITUT NATIONAL DE RECHERCHE ENINFORMATIQUE ET AUTOMATIQUE;LINKOPINGS UNIVERSITET;FUNDACION PARA EL DESAROLLO DE LA INVESTIGACION EN GENOMICA Y PROTEOMICA;CENTRO DI RECERCA SVILUPPO E STUDI SUPRIORI IN SARDEGNA SOCIETA A RESPONSABILITA LIMITADA;INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE;RANNSOKNAMIDSTOD ISLANDS;GENOME RESEARCH LIMITED;STICHTING KATHOLIEKE UNIVERSITEIT;HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH;DEUTSCHE FORSCHUNGSGEMEINSCHAFT;VETENSKAPSRADET - SWEDISH RESEARCH COUNCIL;BUNDESMINISTERIUM FUER BILDUNG UND FORSCHUNG;SIB INSTITUT SUISSE DE BIOINFORMATIQUE;UNIVERSITE VICTOR SEGALEN BORDEAUX II;TECHNISCHE UNIVERSITAET BRAUNSCHWEIG;SARDEGNA RICERCHE;MAGYAR TUDOMANYOS AKADEMIA TERMESZETTUDOMANYI KUTATOKOZPONT;THE ISRAELI MINISTRY OF SCIENCE, CULTURE AND SPORT;CONSIGLIO NAZIONALE DELLE RICERCHE;DANMARKS TEKNISKE UNIVERSITET;BIOTECHNOLOGY AND BIOLOGICAL SCIENCES RESEARCH COUNCIL;SYNGENTA LIMITED;ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM;INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE;THE WELLCOME TRUST LIMITED;MEDICAL RESEARCH COUNCIL;BARCELONA SUPERCOMPUTING CENTER - CENTRO NACIONAL DE SUPERCOMPUTACION;CSC-TIETEEN TIETOTEKNIIKAN KESKUS OY;MAGYAR TUDOMANYOS AKADEMIA SZEGEDI BIOLOGIAI KOZPONT ENZIMOLOGIAI INTEZET;NATURAL ENVIRONMENT RESEARCH COUNCIL";"ES;NL;FR;SE;IT;IS;UK;DE;CH;HU;IL;DK;FI";/SCI;1;0;0;1;0;0 99005;273475;REXPIRE;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-IEF;FP7;RFID EXPERIENCE AND PRIVACY IN THE RETAIL ENVIRONMENT. INDICATIONS FOR IN-STORE CONSUMER RESEARCH;2011-12-01;2014-01-31;;"'This two years research project adopts an interdisciplinary approach by merging social-psychology research with computer technologies developments in the built environment to reach three main goals: 1) understanding the impact of social-psychological factors on issues of ‘privacy concerns’ for ubiquitous technologies within the context of consumption; 2) exploring how the adoption of ubiquitous technologies (such as RFID-enabled services) affects consumers’ perception of the in-store environment and influences consumer experience; 3) the test of mobile devices for in-store consumer research. The first two research goals draw on emerging questions in the ICTs and consumer psychology literatures whereas with the third one indications for a business application of technology are sought. The first research objective is pursued by means of two studies: 1) qualitative in-store interviews to verify consumers’ needs for privacy in different behavioural contexts of RFID-enabled information services. Data will explain the relations between consumers’ profiles, goal orientations, products, information provided by technology, and privacy needs. 2) an experimental study on the impact of perceived control/empowerment on privacy concerns and trust as dependent variables. The second research goal is pursued by examining consumers’ narratives of their experience in the shopping context. Phenomenic Qualitative Interviews are conducted after consumers use of RFID-enabled services within the in-store space. A novel approach to qualitative interviewing for the study of experience is attempted by prompting consumers introspection and self-reports via mobile devices. Data analyses account for age differences in order to identify special key issues for the elderly segment and formulate possible guidelines. Finally, data from the above studies are merged with usability testing to develop a new device for in-store consumer research.'";279680;279680;FP7-PEOPLE-2010-IEF;/MC-IEF;UNIVERSITY COLLEGE LONDON;UK;;;"/EMP;/EDU;/NET";1;0;0;1;0;0 97086;260162;3ENCULT;ONG;FP7-ENVIRONMENT;EeB.ENV.2010.3.2.4-1;FP7;Efficient ENergy for EU Cultural Heritage;2010-10-01;2014-03-31;;"The project 3ENCULT bridges the gap between conservation of historic buildings and climate protection, which is not an antagonism at all: historic buildings will only survive if maintained as living space. Energy efficient retrofit is useful for structural protection as well as for comfort reasons - comfort for users and “comfort” for heritage collections. The joint task of conservation and energy efficient retrofit is highly interdisciplinary. The 3ENCULT consortium consists of scientists and stakeholders, especially on the level of SMEs, from the fields of diagnostics, conservation, building physics, sustainability, architecture and lighting up to cybernetics, thus guaranteeing both, the development of sustainable solutions and the impact on European economy. Eight case studies will demonstrate and verify solutions that are applicable to the majority of European built heritage in urban areas. Building owners and local historic preservation agencies are integrated in local case study teams. 3ENCULT will demonstrate the feasibility of “Factor 4” to “Factor 10” reduction in energy demand, depending on the case and the heritage value. The main objectives are the development of passive and active solutions for conservation and energy efficient retrofit including available products as well as new developments by involved SMEs, the definition of diagnosis and monitoring instruments, the long term monitoring (also for IEQ controlling) and the planning and evaluation tools and concepts supporting the implementation, the quality assurance and control of success of the energy retrofit measures. Guidelines will be disseminated to the scientific and public community. Finally, position papers will be issued suggesting possible integrations and/or implementations of the present regulation framework for improving energy efficiency of historic buildings in urban areas and in particular EPBD and Environmental Impact Assessment as well as Aalborg Commitments and Leipzig Charter.";6704955,74;4990475;FP7-2010-NMP-ENV-ENERGY-ICT-EeB;/CP;ACCADEMIA EUROPEA DI BOLZANO;IT;"YOURIS.COM;COMUNE DI BOLOGNA;ARTEMIS SRL;NEDERLANDSE ORGANISATIE VOOR TOEGEPAST NATUURWETENSCHAPPELIJK ONDERZOEK TNO;GELBISON ELECTRONICS S.R.L.;REMMERS BAUSTOFFTECHNIK GMBH;OVE ARUP & PARTNERS INTERNATIONAL LIMITED;GRUPO UNISOLAR S.A.;BARTENBACH GMBH;INSTITUT FUR DIAGNOSTIK UND KONSERVIERUNG VON DENKMALEN IN SACHSEN UNDSACHSEN-ANHALT EV;ATREA SRO;ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA;TECHNISCHE UNIVERSITAT DARMSTADT;FUNDACION CARTIF;UNIVERSITAET STUTTGART;ICLEI EUROPEAN SECRETARIAT GMBH (ICLEI EUROPASEKRETARIAT GMBH)*;UNIVERSITAET INNSBRUCK;MENUISERIE ANDRE SARL;DET KONGELIGE DANSKE KUNSTAKADEMIS SKOLER FOR ARKITEKTUR, DESIGN OG KONSERVERING.;FEDERATIE VAN VERENIGINGEN VOOR VERWARMING EN LUCHTBEHANDELING IN EUROPA VERENIGING;WOLFGANG FEIST;TECHNISCHE UNIVERSITAET DRESDEN";"BE;IT;NL;DE;UK;ES;AT;CZ;FR;DK";/ENV;1;0;0;1;0;0 96504;253649;ADSCFT MUNICH;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IEF;FP7;The gauge gravity duality and its applications to real world strongly coupled systems;2011-01-01;2012-12-31;;"The fellow’s research area is high energy theoretical physics. Specifically, in using methods from string theory to understand some of the most complex, and least understood areas of elementary particle physics. Through a profound observation into the link between theories of gravity, described by string theory, and the fundamental forces of particle physics, we have access to tools which allow insight into some of the most complicated areas of fundamental physics. Not only is this allowing us to answer questions about these forces which would previously have been impossible, but it is also giving us a deeper understanding into the very nature of space and time. In addition to this, advances in the field over the last few years have meant that we are now able to use these same methods from string theory to look at condensed matter phenomena, which can be studied in the laboratory but where an understanding of their underlying mechanisms is still lacking. In this proposal an outline is given of the ways in which the fellow will be able to answer some of the remaining questions in this fascinating area. From the ideas set out in this proposal a series of important results over the two year period of the fellowship can be delivered. The areas of application which will be discussed in detail are: 1) String theory methods for understanding thermodynamic and hydrodynamic properties of the strong force at high temperature. 2) String theory methods for understanding mesonic and baryonic physics in cold nuclear matter and in the high temperature phase. 3) String theory methods for understanding superconductivity and superfluidity. The interdisciplinary aspects of this proposal linking string theory, heavy ion physics, high energy experimental physics, lattice and condensed matter";155461;155461;FP7-PEOPLE-2009-IEF;/MC-IEF;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;DE;;;"/SCI;/EDU;/ITT";1;0;0;1;0;0 99759;259842;ANTIFLU;ONG;FP7-HEALTH;HEALTH.2010.2.3.3-4;FP7;Innovative anti-influenza drugs excluding viral escape;2011-06-01;2016-11-30;;"ANTIFLU is to develop innovative drugs against influenza virus infections based on a novel concept that precludes the development of viral resistance and ensures efficacy against upcoming pandemic influenza strains. Viral replication is known to depend on multiple host factors. Whilst traditional anti-influenza treatments usually target viral factors, ANTIFLU will aim at drugs interfering with host-response pathways. The concept of drugs targeting human factors, established in treatment of other diseases, has yet not been sufficiently explored for treatment of viral infections, although it bears compelling advantages over conventional antiviral therapies: (i) the avoidance of viral escape mutants and (ii) the broad coverage against unprecedented viral variants. ANTIFLU aims to fully exploit this potent approach to fill critical gaps in our current treatment and prevention options against seasonal and pandemic influenza virus infections. By building upon an existing panel of potent human targets and firm knowledge derived from FP6 project RIGHT, an interdisciplinary consortium will pursue the identification and validation of small molecule ligands and inhibitory RNA molecules effective against influenza infection. Promising modulators will form the basis to generate lead molecules that will be further refined to yield clinically applicable therapeutics. Initial preclinical studies will aim at providing proof of concept in animal models, safety and toxicology profiles. They will allow initiating complete clinical trials immediately after the phase of FP7 support, thanks to the commitment already taken by investors from the private sector. The consortium includes several SMEs, internationally renowned research groups and clinical institutions with extensive experience in anti-influenza treatment and clinical trials. An already agreed common exploitation model will provide a smooth route to market and optimal use of the project results.";7821685,4;5999998;FP7-INFLUENZA-2010;/CP-FP;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;DE;"AARHUS UNIVERSITET;IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE;FORSCHUNGSVERBUND BERLIN EV;LEAD DISCOVERY CENTER GMBH;VICHEM CHEMIE KUTATO KFT;RiboTask ApS;INSTITUT PASTEUR;ARTTIC;MEDITOX S.R.O;THE HEBREW UNIVERSITY OF JERUSALEM";"DK;UK;DE;HU;FR;CZ;IL";"/MED;/MBI";1;0;0;1;0;0 109789;607394;SEDITRANS;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-ITN;FP7;Sediment transport in fluvial, estuarine and coastal environment;2013-09-01;2017-08-31;;Sediment transport in the fluvial, estuarine and coastal environment causes significant morphological changes and results in the amplification of floods, storm surges and other inundation hazards. This increases considerably the risk of failure of structures, disruption of function of networks (water, energy), destruction of ecosystems and natural resources, as well as property and human loss. The impact of sediment transport is expected to be incremented due to climate change. Thus, it is very important to advance knowledge and train future engineers in this field. Herein we propose the formation of a Network for the training of young researchers in all application areas of sediment transport. The Network consists of six academic and four industrial partners and provides an elaborate and interdisciplinary training-through-research program to 12 early stage and 4 experienced researchers. It includes a comprehensive academic program, secondments at industrial partners, workshops, winter and summer schools, thematic conferences, production of guidelines and complementary activities. The proposed research focuses on: i) modeling and algorithm development for sediment transport in river and coastal flows and for inland and offshore turbidity currents or debris flows, and ii) experiments and simulations of sediment transport in river and coastal flows, and sediment-laden density underflows in reservoirs and submarine canyons. The experiments will allow for crucial phenomenological advances in the conceptual models upon which simulation tools are built. The latter, compatible with high performance computing, will be explored jointly by academic an industrial partners in real engineering applications during and after the duration of the project. This network is structured to help the coordination of research and educational activities in sediment transport in a European level and increase the European competitiveness in this important field of S&T.;3734061,89;3734061,89;FP7-PEOPLE-2013-ITN;/MC-ITN;PANEPISTIMIO PATRON;EL;"UNIVERSITA DEGLI STUDI DI TRIESTE;STUCKY SA;UNIVERSITE CATHOLIQUE DE LOUVAIN;ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE;LABORATORIO NACIONAL DE ENGENHARIA CIVIL;IDROSTUDI SRL;FUGRO BELGIQUE SA;UNIVERSITY OF CYPRUS;INSTITUTO SUPERIOR TECNICO";"IT;CH;BE;PT;CY";/LIF;1;0;0;1;0;0 90657;237149;FAR-QUAD;ONG;FP7-PEOPLE;FP7-PEOPLE-IIF-2008;FP7;FoldAmeRs : a new family of G-QUADruplex ligands;2009-03-01;2011-02-28;;"This proposal focuses on the formation of complex between DNA G-quadruplexes and a new family of synthetic ligands, which might be relevant for cancer therapy. The enzymatic acitivity of telomerase is critical to the immortality of most human cancer cell lines. However, telomeric DNA may fold into guanine quadruplex structures which are not competent substrates for telomerase. Therefore, the use of small molecule ligands to induce quadruplex stabilisation in telomeric DNA has potential as an anti-cancer strategy. A European collaboration recently engaged between I. Huc (Bordeaux, France) and S. Balasubramanian (Cambridge, UK) groups already led to the identification of a very promising compound, with exceptionnal potential for stabilising human G-quadruplex telomer. In addition a three dimensionnal helical compound (foldamer) has shown interesting activity. This project, involving chemistry, biology and biophysic, aims i) to systematically design and develop new analogues of this promising candidate, based on aromatic delta-peptide chemistry; ii) to evaluate their G-quadruplex binding affinity in telomere and others systems; iii) to establish structure-activity relationships; iv) to determine the key elements necessary for specific G-quadruplex recognition by solving the structure of the first ligand complexed with G-quadruplex. This original interdisciplinary proposal involves two international leading groups in their respective field, to develop new tools and knowledge on the growing interest on natural G-quadruplexes as new target for anti-cancer strategy. The applicant will have a crucial role in the development of this collaboration and will become an active and efficient third partner, when returning back to China at the end of the fellowship.";;174535,75;FP7-PEOPLE-IIF-2008;/MC-IIF;UNIVERSITE DE BORDEAUX I;FR;;;"/SCI;/EMP";1;0;0;1;0;0 93096;238778;ATTRACT;ONG;FP7-PEOPLE;FP7-PEOPLE-ITN-2008;FP7;Advanced Teaching and TRaining for Adoptive Cell Therapy;2009-10-01;2013-09-30;;Considerable resources are devoted to fighting cancer throughout Europe, yet these efforts are not producing the results that health practitioners and citizens might expect. This is partly due to the fragmentation and duplication of research efforts within Member states and the lack of co-ordination at European level. However it can also be attributed to the need to retain and most importantly develop researchers within the EU who have the research skills required to make a real contribution to cancer treatment. The need for quality researchers is particularly acute within the emerging interdisciplinary field of Adoptive Cell Therapy. This promising advance in cancer treatment is based on the exploitation of tumour immunology and genetic technology and built on the specific ideas and techniques originally proposed by the European and Israeli scientists who are members of the ATTRACT network. To facilitate further development within the field of adoptive cell therapy, it is crucial that a co-ordinated and intersectoral approach (combining both the research community and industry) is taken, an approach that broadens the portfolio of skills currently retained within the EU research community. Through the integration Europe’s undisputed leaders in the field of adoptive cell therapy established in the 2005 FP6 ATTACK project, the ATTRACT network aims to foster the development of a pool of ESR’s and ER’s by equipping them with the multidisciplinary and complementary skills needed to not only initiate further advances in the field but to become future leaders within the field of adoptive cell therapy for cancer treatment. Such skills are global in demand making each researcher a highly desirable candidate for employment and very mobile across the different career domains.;2838539,06;2838539,06;FP7-PEOPLE-ITN-2008;/MC-ITN;THE UNIVERSITY OF MANCHESTER;UK;"KLINIKUM DER UNIVERSITAET ZU KOELN;THE CHRISTIE NHS FOUNDATION TRUST;WEIZMANN INSTITUTE OF SCIENCE;Fondazione Centro San Raffaele;MILTENYI BIOTEC GMBH;MAX-DELBRUCK-CENTRUM FUR MOLEKULAREMEDIZIN;FONDAZIONE CENTRO SAN RAFFAELE;STICHTING HET NEDERLANDS KANKER INSTITUUT-ANTONI VAN LEEUWENHOEK ZIEKENHUIS;OSPEDALE SAN RAFFAELE SRL;HUMANITAS MIRASOLE SPA;ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM;UNIVERSITY COLLEGE LONDON;MOLECULAR MEDICINE SPA;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS";"DE;UK;IL;IT;NL;FR";"/SCI;/EDU";1;0;0;1;0;0 92403;235596;HHG-NANOTOMOGRAPHY;ONG;FP7-PEOPLE;FP7-PEOPLE-IOF-2008;FP7;High-Harmonic tomography and characterization of Nano-structures;2009-05-01;2012-10-31;;Progress in nanoscience and nanotechnology depends not only on examining the surfaces of nanostructures but on looking deep inside to identify what electronic, magnetic, optical, and chemical processes are of importance. For characterizing internal variations in shape, organization, or chemical composition over distances of hundred of nanometers, usage of XUV and soft X-ray electromagnetic radiation not only complements electron microscopy but also offers important advantages. Unfortunately the relevant sources in this spectral region (Synchrotrons and Free Electron Lasers) are extremely large, prohibitedly expensive, and not accessible to most of the scientific community. We propose to use XUV and soft X-rays produced by High Harmonic Generation (HHG), as the source for exploring most advanced multidimensional (3D spatial\1D frequency\1D time) imaging modalities for nanostructures and nanomaterials, and studying their fundamental physical properties and dynamics. Specifically, we propose to research the combination of multicolor nano-tomography and optical coherence tomography with high harmonic generated light, making particular emphasis on three-dimensional volumetric structural and property analysis. We will also use the HHG to study fundamental optical properties of nano-materials in XUV and soft X-ray region of spectrum - very important and largely unexplored area so far. We believe that such an interdisciplinary approach (attoscience techniques applied into nanoscience) can result in qualitatively new advances in the field.;324540,48;324540,48;FP7-PEOPLE-IOF-2008;/MC-IOF;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;DE;;;"/COO;/EDU";1;0;0;1;0;0 96225;261224;DNAMETRY;ONG;FP7-IDEAS-ERC;ERC-SG-LS1;FP7;DNA based nanometry: Exploring chromatin structure and molecular motors;2011-01-01;2016-10-31;;DNA metabolism is governed by a delicate balance between compacting the stored genetic information while simultaneously ensuring a highly dynamically access to it. This interdisciplinary project aims (i) to understand the mechanics and dynamics of chromatin as well as the mechanism of enzymes involved in DNA metabolism on a molecular level and (ii) to develop new nanometric tools based on optical methods and 3D DNA nanostructures that allow addressing new experimental questions. Within the research project novel nanoscopic detection assays based on the combination of magnetic tweezers and optical methods shall be developed, such as ultra-fast torque spectroscopy and combined FRET-force spectroscopy. Our single-molecule assays shall be applied to study the material properties of self-assembled 3D DNA nanostructures, which shall then be used to set up improved high resolution single-molecule assays. These technological improvements will become key to obtain insight into structure and dynamics of in vitro reconstituted chromatin as response to external mechanical stress but also into the operation of molecular motors that themselves generate forces and torques on DNA and chromatin. The main goal of the project is to use nanotechnological tools to understand design principles of biomolecules, biomaterials and biological motors, which in turn shall be used to develop smarter nanotools and functional elements.;1500000;1500000;ERC-2010-StG_20091118;/ERC-SG;UNIVERSITAET LEIPZIG;DE;"WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER;TECHNISCHE UNIVERSITAET DRESDEN";DE;"/BIO;/LIF";1;0;0;1;0;0 100286;282551;EPOCAN;ONG;FP7-HEALTH;HEALTH.2011.4.2-2;FP7;Gaining sage on the Epoetins' saga: assessing long term risks and advancing towards better Epoetin driven treatment modalities;2011-10-01;2014-09-30;;"EpoCan aims to develop and implement a comprehensive interdisciplinary strategy to assess the long-term risks of erythropoietin (EPO) and its derivatives (epoetins) on tumour growth progression and thromboembolic events in cancer patients, cardiovascular events, and the development of cancer in chronic kidney disease. Approximately 400,000 patients across Europe receive epoetins treatment each year. Recent meta-analysis data have raised concerns over increased mortality in some patient groups. Hence the urgent need to evaluate the risk-benefit ratio of epoetin treatment and its potential long-term effects. EpoCan brings together a multidisciplinary consortium of 12 world leading academic, industrial and medical partners, with long-standing, complementary expertise in haemostasis, oncology and EPO biology. EpoCan aims to (1) Identify, detect and measure possible long-term hazards of epoetin treatment; (2) Develop novel prognostic tools and new complementary therapeutic reagents: (3) Evaluate the risk-benefit ratio to pave the way for new safety and efficacy criteria. EpoCan will: (a) Utilize a wide array of cellular models to thoroughly analyze EPO/EPO receptor(EPO-R)interaction and signalling, to define the relationship between EPO-R expression in tumour samples and the clinical outcome in cancer patients; (b) Establish and test new, personalized, predictive tools (EPO-R peptide antagonists, novel specific anti-EPO-R monoclonal antibodies, thromboembolic tests); (c) Create new murine models as hosts for tumour implantation subjected to EPO and derivatives established above; (d) Screen and analyze clinical databases; (e) Define models to predict hazardous versus safe/beneficial roles of epoetins in the treatment of cancer and kidney failure associated anaemia. Data obtained will be integrated into coherent models using novel computational algorithms developed for EpoCan. Results are expected to have broad ramifications, with special relevance for clinical oncology.";3927556,8;2995103,6;FP7-HEALTH-2011-single-stage;/CP-FP;TEL AVIV UNIVERSITY;IL;"ACADEMISCH ZIEKENHUIS LEIDEN;DEUTSCHES HERZZENTRUM MUNCHEN;ALDEVRON FREIBURG GMBH;UNIVERSITAET DUISBURG-ESSEN;OSM-DAN LTD;THE QUEEN'S UNIVERSITY OF BELFAST;MEDIZINISCHE UNIVERSITAT INNSBRUCK;UNIVERSITAT ZURICH;UNIVERSITAIR MEDISCH CENTRUM UTRECHT;VETERINAERMEDIZINISCHE UNIVERSITAET WIEN;UNIVERSIDAD AUTONOMA DE MADRID;WINZSOFT (ISRAEL) LTD";"NL;DE;IL;UK;AT;CH;ES";/LIF;1;0;0;1;0;0 103035;302902;QUANTUM METROLOGY;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IOF;FP7;Measuring Magnetic Monopoles Using Quantum Metrology in Diamond;2012-09-01;2015-08-31;;This proposal seeks to develop state of the art quantum metrology in diamond to probe a magnetic monopoles in spin ice. It will accomplish this by establishing an interdisciplinary collaboration between two world-leading groups, the Yacoby group at Harvard and the Bramwell group at the London Centre for Nanotechnology at University College London. Since the Harvard group purchases the diamond samples commercially, and this fellowship will allow the transfer of their expertise, it offers a particularly sustainable route to the permanent integration of the knowledge in the EU. The results of this fellowship promise to be extremely intersting from both a fundamental and technological perspective, and it is expected to lead to several high profile publications.;271943,7;271943,7;FP7-PEOPLE-2011-IOF;/MC-IOF;UNIVERSITY COLLEGE LONDON;UK;;;/SCI;1;0;0;1;0;0 90608;236605;HELICAL TRANSPORTERS;ONG;FP7-PEOPLE;FP7-PEOPLE-IEF-2008;FP7;AROMATIC FOLDAMERS AS DRUG DELIVERY CARRIERS;2009-04-01;2011-03-31;;The Huc group is a world leading research team in the fields of Biomimetic and Bioorganic Chemistry. One of group’s main contributions is focused on the synthesis, structural elucidation and biological application of aromatic oligoamides. These compounds adopt exceptionally stable folded conformations, helices, stabilised by intramolecular hydrogen bonds and - interactions. The high structural predictability, tunability, ease of synthesis and resistance to hydrolysis of such foldamers has led to an increasing attention towards those oligoamides. Very recently, Huc and co-workers have proven that despite the high hydrophobicity of those aromatic foldamers, they can be made highly hydrosoluble by inserting cationic side chains, providing important possibilities for their biological application as cell penetrating agents. This project focuses on the investigation of structural characteristics and the ability of aromatic oligoamides to cross the cellular membrane and deliver different cargoes efficiently. The qualitative and quantitative determination of uptake of the helices, intracellular trafficking and translocation of cargo will very importantly allow us to gain an insight into the kinetics and mechanism underlying the cellular translocation, areas that are currently being subject to a lot of controversy. The project is concerned with an emerging area of interdisciplinary chemical research in which the development of drug delivery technologies based on the new understanding of cross-membrane transport is expected to have a very strong impact on health and the design of novel therapeutic and diagnostic agents.;;164877,53;FP7-PEOPLE-IEF-2008;/MC-IEF;UNIVERSITE DE BORDEAUX I;FR;;;"/SCI;/EMP";1;0;0;1;0;0 87694;203475;PROTMOD;ONG;FP7-IDEAS-ERC;ERC-SG-LS2;FP7;Dynamics and stability of covalent protein modifications;2008-09-01;2014-08-31;;'One of the major goals of post-genomic biological research is to understand the molecular basis and physiological role of covalent protein modifications. Post-transcriptional modifications can regulate protein interactions and/or stability and thus trigger particular downstream responses. A major challenge is to understand how modifications of histone proteins are translated into changes in gene expression and chromatin structure and how they regulate genome function. However, the significance of studying protein modifications extends beyond the field of chromatin research, because changes in the modification pattern are likely to affect many -if not all- biological processes. This proposal is designed to study and functionally characterise modifications of histones. The goals of this proposal are: A) Determining the role of linker H1 modifications and variants in epigenetic regulation of gene expression. This will enable us to expand the 'histone' code to the next higher level of chromatin organisation. B) To identify yet uncharacterised sites or new types of histone modifications. This will be the basis for determining the biological function of these modifications. Altogether this will lead us to decipher the role of covalent protein modifications in regulation of gene expression and how they are linked into biological networks . These projects will significantly expand the scope of my ongoing research and will only be possible with additional funding, which will allow me to establish cutting edge technology, additional in vivo model systems and new interdisciplinary collaborations.';1239400;1239400;ERC-2007-StG;/ERC-SG;CENTRE EUROPEEN DE RECHERCHE EN BIOLOGIE ET MEDECINE;FR;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;DE;"/BIO;/LIF";1;0;0;1;0;0 106002;313369;TRANSFORMIG;ONG;FP7-IDEAS-ERC;ERC-SG-SH3;FP7;Transforming Migration: Transnational Transfer of Multicultural Habitus;2013-03-01;2018-02-28;;"How do migrants develop the competence to successfully operate within a new society, and will these newly acquired intercultural skills and attitudes transfer between individuals and geographical locations? Can migration, and to what extent, trigger a shift towards more tolerance and respect for ethnic and cultural diversity in the countries sending migrants? And how are these effects mediated by particular conditions? These are the questions the TRANSFORmIG project seeks to answer by investigating recent massive migration between Poland and Great Britain and Germany. The ‘Polish case’ is highly instructive because of diametrically opposed contexts between which the transnational migrants regularly ‘switch’: Britain and Germany are characterized by a level and kind of multi-cultural complexity that is unknown to immigrants from Poland which is recognized as one of the most ethnically homogeneous country in the world. The TRANSFORmIG project puts the hypothesis that contact with diversity – socializing with people of diverse backgrounds – leads to (a positive) change of attitudes both among migrants and their peer groups in the communities of origin, and that these effects are mediated by the particular configurations and representations of diversity. The TRANSFORmIG project entails interdisciplinary, multi-method research in selected localities in Great Britain, Germany and Poland. Spanning sociology, anthropology, history and media studies, the project investigates with the help of a longitudinal qualitative study, individual and group interviews, ethnography and discourse analysis how people’s attitudes and skills to act in diverse societies change over time and in dependence with historical and contemporary conditions. Findings will significantly advance social scientific understanding of the processes of transnational transfer of values and attitudes and the spread of intercultural competences under the condition of growing diversification of societies.";1349896;1349896;ERC-2012-StG_20111124;/ERC-SG;HUMBOLDT-UNIVERSITAET ZU BERLIN;DE;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;DE;/SOC;1;0;0;1;0;0 110645;610704;SIMPOL;ONG;FP7-ICT;ICT-2013.5.4;FP7;Financial Systems Simulation and Policy Modelling;2013-11-01;2017-02-28;;This project proceeds from the vision that fundamental advances of policy modelling in finance and climate finance can only stem from a genuinely interdisciplinary approach where network science, big data and ICT's meet economics and financial regulation. Accordingly, on the one hand we will develop new methods to assess the systemic importance of market players in (climate) financial networks and we will evaluate the effect of regulations in close collaborations with representatives of various regulatory bodies. The results will contribute to the discussion on how financial innovations could ignite a transition towards a greener economy and a more sustainable financial system. On the other hand, we will leverage on open data initiatives and semantic web to empower citizens with a more active role in relation to EU policies, by crowd-sourcing the mapping of the networks of influence involved in the policy making process.;2486334;1826000;FP7-ICT-2013-10;/CP;UNIVERSITAT ZURICH;CH;"INSTITUT JOZEF STEFAN;UNIVERSITE PARIS I PANTHEON-SORBONNE;GCF - GLOBAL CLIMATE FORUM EV;SCUOLA IMT (ISTITUZIONI, MERCATI, TECNOLOGIE) ALTI STUDI DI LUCCA;LONDON CENTRE FOR MATHEMATICAL SCIENCES LBG";"SI;FR;DE;IT;UK";/INF;1;0;0;1;0;0 185498;607775;E-CRIME;ONG;FP7-SECURITY;SEC-2013.2.5-2;FP7;Economic impacts of Cybercrime;2014-04-01;2017-03-31;;Some progress has been made in understanding and managing cyber crime as well assessing its economic impact. Yet much remains to be done. Lack of co-ordination in law enforcement and legislation, lack of common consensus on the nature of cyber crime and lack of knowledge sharing and trust are just some of the issues that both afflict cyber crime responses and cloud our understanding of cyber crime. E-CRIME addresses these well-known problems, while analysing the economic impact of cyber crime and developing concrete measures to manage risks and deter cyber criminals in non-ICT sectors. E-CRIME does so by adopting an interdisciplinary and multi-level-stakeholder focused approach that fully integrates a wide range of stakeholders’ knowledge and insights into the project. First, the project will create a detailed taxonomy and inventory of cyber crime in non-ICT sectors and analyse cyber criminal structures and economies by combining the best existing data sources with specialist new insights from key stakeholders and experts. Second, E-CRIME will assess existing counter-measures against cyber crime in non-ICT sectors in the form of current technology, best practices, policy and enforcement approaches, and awareness and trust initiatives. Third, having mapped the as-is of cyber crime, the project will use available information and new data to develop a multi-level model to measure the economic impact of cyber crime on non ICT-sectors. Fourth, E-CRIME will integrate all its previous findings to identify and develop diverse, concrete counter-measures, combined in portfolios of inter-sector and intra-sector solutions, including enhancement for crime-proofed applications, risk management tools, policy and best practices, and trust and confidence measures. The analysis will proceed in close co-operation with relevant and diverse stakeholders. This will be achieved through conducting interviews and survey, organising workshops and setting up an E-CRIME Stakeholder Forum.;3759113,44;3004180,07;FP7-SEC-2013-1;/CP-FP;TRILATERAL RESEARCH LTD;UK;"THE INTERNATIONAL CRIMINAL POLICE ORGANIZATION;UNIVERSITE DE LAUSANNE;TRILATERAL RESEARCH & CONSULTING LLP;IPSOS BELGIUM SA;THE UNIVERSITY OF WARWICK;RIJKSUNIVERSITEIT GRONINGEN;UNIVERSITAET INNSBRUCK;WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER;GLOBAL CYBER SECURITY CENTER;TALLINNA TEHNIKAULIKOOL;TECHNISCHE UNIVERSITEIT DELFT";"FR;CH;UK;BE;NL;AT;DE;IT;EE";/SAF;1;0;0;1;0;0 186982;314632;EU-GUGLE;;FP7-ENERGY;EEB.ENERGY.2012.8.8.3;FP7;European cities serving as Green Urban Gate towards Leadership in sustainable Energy;2013-04-01;2018-03-31;;"The EU-GUGLE project mobilises public / private resources to build showcases of totally around 226,000 m2 of cost-efficient urban Zero Carbon Building Renovation models in AT, FI, DE, IT, SK & ES - together with associated cities in SE&TR. EU-GUGLE is designed to respond to the needs of an effective take-off of the Smart City initiative within the EU SET-plan and in particular by demonstrating different sustainable energy technologies and techniques integrated in an intelligent way within lighthouse buildings. Although the individual demonstration projects are independent from each other, being designed to fulfil local building-user needs and utilising local resources perfectly integrated in these smart objects, there are many similarities between them. The foreseen implementation plan is a symbiosis of integrating activities, such as ? Sharing latest research results especially of retrofitting technologies & smart RES integration into buildings ? Demonstrating appropriate energy solutions in order to reach energy savings of 25.6 GWh/a for heating and DHW and 2.5 GWh/a for electricity in terms of primary energy ? Establishing adequate business environment favourable for Smart City demonstrations ? Serving as benchmark for sustainable buildings&districts and spreading best-practice ? Implementing innovative retrofitting technologies & techniques validated in six partner cities ? Developing a transparent EU-GUGLE model for immediate replication in three associated cities and abroad. ? Connecting social needs of building-users with innovative market actors. By deploying an interdisciplinary approach, an innovative / cost-efficient mix of actions, a set of sustainability oriented solutions will be pointed out and transferred to and among the identified target groups of EU-GUGLE. The outcomes and related benefits will be fully exploited by an effective range of actions generating local activities with high visibility character together with the major stakeholders. ";30140289,6;16785372;FP7-2012-NMP-ENV-ENERGY-ICT-EeB;/CP-SoU;FUNDACION CENER-CIEMAT;ES;"HEMMERS ROSA MARIA - SYNERGIEKOMM AGENTUR FUR NACHHALTIGKEIT UND INNOVATION;STADT AACHEN;HLAVNE MESTO SLOVENSKEJ REPUBLIKY BRATISLAVA;STADTWERKE AACHEN AKTIENGESELLSCHAFT;COMUNE DI MILANO;GAZIANTEP BUYUKSEHIR BELEDIYESI;TAMPEREEN KAUPUNKI;TECHNICKY A SKUSOBNY USTAV STAVEBNY n.o.;IC CONSULENTEN ZIVILTECHNIKER GESMBH;MAGISTRAT DER STADT WIEN;GOTEBORGS KOMMUN;UNIVERSITAET FUER BODENKULTUR WIEN;SESTAO BERRI 2010 SOCIEDAD ANONIMA;POLITECNICO DI MILANO;SLOVENSKA RADA PRE ZELENE BUDOVY;GEWOGE AG;AZIENDA LOMBARDA EDILIZIA RESIDENZIALE MILANO;TEKNOLOGIAN TUTKIMUSKESKUS VTT;ENTE VASCO DE LA ENERGIA;Greenovate! Europe";"DE;SK;IT;TR;FI;AT;SE;ES;BE";/SCI;1;0;0;1;0;0 89957;230662;FOLDAPPI;ONG;FP7-PEOPLE;FP7-PEOPLE-IAPP-2008;FP7;Foldamers against protein-protein interactions;2009-02-01;2014-01-31;;The Foldappi proposal aims to investigate the potential of aromatic amide Foldamers to disrupt protein-protein interactions. The scientific goals of the project include: 1. development of synthetic methods to build foldamers with different R-group chemistries 2. development of strategies to target foldamers to protein surfaces 3. measuring in vitro properties of foldamer(s) to assess ADME profiles of these molecules In this proposal we propose to explore the use of quinoline-derived aromatic amide foldamers developed at the University of Bordeaux to inhibit protein-protein interactions, namely the interaction between interleukin 4 (IL-4) and its receptor. These foldamers have a very well defined structure that lends itself to the rational design of substituents and the production of focused combinatorial libraries of foldamers capable of interacting with the IL4/IL-4R binding epitope. They are also large enough to block a protein-protein interaction, a feat that is not possible with small molecules. The cytokine IL-4 is a key regulator of the immune system determining the formation of immune cells and immunoglobulin class switching. IL-4 is critically involved in misguided immune reactions during atopic diseases as allergy and asthma. In spite of its importance as a drug target, no small molecule inhibitor of the Il-4/IL-4R has been reported so far, warranting the use of foldamers to do the same. The three partners involved in this cooperation, namely UCB Pharma, Université Bordeaux I and Universität Würzburg each have unique expertises necessary to bring this project to completion. This combination will produce breakthrough knowledge and insights into developing chemistries that can impact in health and medical fields. Moreover, this project will contribute to the personal development of the scientists involved by improving their interdisciplinary knowledge, as well as their communication and experimental skills.;1089570;1089570;FP7-PEOPLE-IAPP-2008;/MC-IAPP;UNIVERSITE DE BORDEAUX;FR;"UCB PHARMA SA;UNIVERSITE DE BORDEAUX I;JULIUS-MAXIMILIANS-UNIVERSITAT WURZBURG";"BE;FR;DE";/EDU;1;0;0;1;0;0 103087;298208;FALSEPOVERTY;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IEF;FP7;"""False Poverty: The Cultural, Political and Historical Implications of Literary Accounts of 'Social Passing'""";2012-10-01;2014-09-30;;"'This project aims to examine the genre of 'social passing' in British writing from the late 1800s onwards. These are accounts written by those faking poverty to report upon the poor. The most important literary examination is in Cunningham’s 1988 British Writers of the Thirties, limited to one decade and but one strand of a larger critical analysis; the most important historical-anthropological work is Freeman and Nelson’s introduction to Vicarious Vagabonds, focusing above all on texts 1860-1910. This project, however, proposes an approach both more diachronic and more specific, focusing not only on literary and cultural implications of passing, but also on the reality behind accounts, moving from a purely text-based literary approach towards an interdisciplinary historical study. This project’s ultimate aim is an analysis of the cultural, political and historical implications of these accounts, focusing on their cultural impact on the twentieth-century literary scene, political implications, impact on political debate of the time, and influence on the general public’s perception of poverty, as well as on their historical implications, including the role played as historical sources, and the credibility of data and events reported. The project aims to use a mixture of textual criticism and archival and on-site research. It will focus on historical and political contexts of the writing of primary texts, and on issues related to the condition of the poor discussed (reports, statistics, documents related to voluntary relief activities, the treatment of the subject in newspapers, specialized journals, illustrations and cartoons). In a period of financial crisis and governmental interest in the welfare of the poor, understanding how the poor have been represented over the last century is invaluable; it is also worth examining the mechanisms whereby those self-describing as non-proletariat have related to the working class and tried to change or hide that relationship.'";209033,4;209033,4;FP7-PEOPLE-2011-IEF;/MC-IEF;UNIVERSITY COLLEGE LONDON;UK;;;/SCI;1;0;0;1;0;0 101337;291329;TESTDE;ONG;FP7-IDEAS-ERC;ERC-AG-PE9;FP7;Testing the Dark Energy Paradigm and Measuring Neutrino Mass with the Dark Energy Survey;2012-05-01;2018-04-30;;"One of the greatest mysteries in the whole of science is that 75% of the Universe appears to be made of an enigmatic ‘Dark Energy’. A further 21% of the Universe is made from invisible ‘Cold Dark Matter’ that can only be detected through its gravitational effects, with the ordinary atomic matter making up only 4% of the total cosmic budget. These discoveries require a shift in our perception. I play leadership roles in several large surveys, in particular the $40M international Dark Energy Survey (DES), where I coordinate the entire science programme, with 200 scientists from 5 countries. DES will have its first light in October 2011, with observing from 2012 to 2017. I propose three Themes, which are interlinked: (1) Modelling the cross-talk of DES probes and a feasibility study for a spectroscopic follow-up (DESpec) which will allow testing modified General Relativity models as alternatives to Dark Energy; (2) Attempting for the first time to measure the as yet unknown neutrino mass from DES, including novel modelling of the non-linear power spectrum; and (3) Follow up of an intriguing excess in galaxy clustering on large scales we recently detected in our home-grown MegaZ-LRG sample, and developing new approaches to photometric redshifts. The research is interdisciplinary since it is connected to statistical methods as well as to High Energy Physics. The techniques developed will also be used for many other projects, including the ongoing Hubble Space Telescope CLASH survey of clusters and the planned ESA Euclid space mission. At this stage of my career, after founding the Cosmology area at University College London and playing a key role in setting up DES, I wish to focus on creative research to exploit DES with the help of four Post-docs. I believe this work will significantly influence the next paradigm shift in Cosmology, and it will make a major contribution to Cosmology in Europe.";2416388;2416388;ERC-2011-ADG_20110209;/ERC-AG;UNIVERSITY COLLEGE LONDON;UK;;;"/PSE;/AER;/SPA";1;0;0;1;0;0 89091;209321;SIMP;ONG;FP7-IDEAS-ERC;ERC-SG-PE2;FP7;Ultra-high-Q Physics: Towards single molecules and phonons;2008-09-01;2012-12-31;;The proposed research program builds on the previously developed ultra-high-Q monolithic micro-resonators by the applicant during his dissertation at the “California Institute of Technology”. These micro-resonators offer unprecedented confinement of light in micro-scale volumes for extended amounts of time and have opened many lab-on-chip applications ranging from nonlinear optics, quantum optics to biochemical sensing. This present proposal is concerned to use ultra-high-Q optical micro-cavities as vehicles to study two novel and emerging research opportunities. The first endeavor investigates the possibility to use radiation pressure to cool a mechanical oscillator to the quantum ground state. The significance of the research program lies in its attempt to exploit the opto-mechanical system as a paradigm for the investigation of quantum processes of mechanical objects – a field which has sparked widespread interest in contemporary physics for quiet some time, but which to date remains experimentally unexplored and which is intimately related to concepts used in fields such as gravitational wave detection or scanning probe techniques. From a conceptual point of view, this research could show how a mechanical, macroscopic object reveals quantum mechanical behavior. Ultra-sensitive measurements are also part of a second, interdisciplinary line of research. To date, only a few widely applied techniques in Biophysics are available for label free detection of ligand-receptor binding, which lack single to resolve single molecule binding events. Building on recent advances of the applicant, the proposed methodology will use membrane functionalized micro-resonators in aqueous solution as novel technique to resolve single binding events. By developing a methodology with which label free single molecule sensitivity in biomolecular recognition can be attained, this research could enable to open new frontiers to Biophysicists.;1332000;1332000;ERC-2007-StG;/ERC-SG;ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE;CH;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;DE;"/PSE;/SCI";1;0;0;1;0;0 103209;298127;GLASS;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IEF;FP7;GLASS: Glass in Late Antiquity: Science and Society;2012-11-01;2014-12-01;;"'The GLASS Project builds upon excavations at Tell Basta/Bubastis (Egypt) where a large amount of Late Antique glass (appr. 2500 fragments so far, mainly 2nd – 7th cent. AD) has been excavated. Using this glass corpus as a case study, GLASS seeks to address the lack of research about Late Antique to Early Islamic glass from Egypt and its trade by combining archaeological, chemical, and historical methods. Five key research questions (=Milestones) – namely 1. glass supply and consumption in Bubastis 2. trade patterns 3. recycling issues 4. the status of glass objects and 5. glass imitation – will be addressed and result in databases, catalogues and articles (Deliverables 1-4). The project will be based at the UCL Institute of Archaeology and include chemical analyses of glass from Bubastis on site with a portable XRF, and of contemporary and provenanced glass from relevant UK collections by electron microprobe and LA-ICPMS. Based on my good understanding of artefact typology, archaeological context and analytical methods, I will combine chemical analysis and typo-chronological studies on the basis of archaeological excavations in order to gain new knowledge about Egyptian glass production, working, distribution, usage and trade in the Late Antique world. I will integrate these results into a larger discussion and draw conclusions concerning various economic, cultural, social and historical aspects of Egypt's glass use and consumption in the context of the Mediterranean glass trade throughout the Late Antique and Early Islamic periods. The project will thus pioneer broader directions of inquiry and new, interdisciplinary approaches to the investigation of past cultures.'";200371,8;200371,8;FP7-PEOPLE-2011-IEF;/MC-IEF;UNIVERSITY COLLEGE LONDON;UK;;;/SCI;1;0;0;1;0;0 91275;228625;INLIVETOX;ONG;FP7-NMP;NMP-2008-1.3-2;FP7;Intestinal, Liver and Endothelial Nanoparticle Toxicity Development and evaluation of a novel tool for high-throughput data generation;2009-05-01;2012-07-31;http://www.inlivetox.eu;The InLiveTox project will form an interdisciplinary consortium at the European level, together with a key American research group to develop an improved in vitro model for the study of nanoparticle (NP) uptake, transport and cellular interaction, thus advancing our understanding of NP toxicity. Rather than repeat what has, or is being done in the field of aerosol NP and lung toxicology, InLiveTox will focus on the impact of NP exposure via ingestion, in the healthy and diseased gastrointestinal (GI) tract, vascular endothelium and liver. The key questions in this study are: (i) How do these tissues individually respond to NPs? (ii) How do the interactions between the different tissues modulate their responses? (iii) How does inflammation affect the toxicity of NPs and their ability cross the intestinal barrier? (iv) Which physico-chemical characteristics of NPs influence their uptake by intestinal epithelial cells and their subsequent interactions with endothelial and liver cells? The objective of InLiveTox will be to develop a novel modular microfluidics-based in vitro test system modelling the response of cells and tissues to the ingestion of NPs. Cell culture modules of target tissues such as the GI tract, the liver and the endothelium will be connected via a microfluidics system so that knock-on and cross talk effects between organs and tissues can be monitored. A major innovative aspect of the InLiveTox project pertains to the implementation of biological tissue models in a microfabricated compartmental cell culture system that allows multiple cell types to be addressed and investigated in combination. This system will be much easier, more convenient and ethically less questionable than animal testing, as well as more relevant than the in vitro single cell /co-culture models currently used. For this study, applications of the model will focus on NP toxicology, but the system could also be widely used in various applications of toxicology and pharmacology.;3420762,33;2399989;FP7-NMP-2008-SMALL-2;/CP-FP;CSEM CENTRE SUISSE D'ELECTRONIQUE ET DE MICROTECHNIQUE SA - RECHERCHE ET DEVELOPPEMENT;CH;"UNIVERSITY OF ROCHESTER;AYMING;HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH;KIRKSTALL LIMITED;UNIVERSITA DI PISA;HERIOT-WATT UNIVERSITY;EDINBURGH NAPIER UNIVERSITY;UNIVERSITAT DES SAARLANDES";"US;FR;DE;UK;IT";"/ENV;/MED;/NNT";1;0;0;1;0;0 98590;267219;EXOMOL;ONG;FP7-IDEAS-ERC;ERC-AG-PE9;FP7;ExoMol: molecular line lists for exoplanet atmospheres;2011-05-01;2016-04-30;;"The discovery of extrasolar planets was one of the major advances of the last two decades. Over 400 planets have now been detected and astronomers are beginning to characterise their composition and physical characteristics. To do this requires huge quantities of spectroscopic data most of which is not available from laboratory studies. The interdisciplinary ExoMol project will provide a comprehensive solution to this problem by providing spectroscopic data on all the molecular transitions of importance in the atmospheres of exoplanets. This data will be widely applicable to other problems and will be used for studies on cool stars, brown dwarfs and circumstellar environments. ExoMol will also be used by scientists who study spectra of hot molecules in a other situations such as combustions. A mixture of first principles and empirically tuned quantum mechanical methods will be used to compute comprehensive and huge (up to 100 billion transitions) line lists. Novel methodologies will be developed for treating larger molecules such as methane and nitric acid. The success of ExoMol will rely on these developments and the use of state-of-the-art computing. The ExoMol database will from part of the EU Virtual Atomic and Molecular Data Centre (VAMDC). A program to promote application of the data by a wide variety of users will be initiated.";2472032;2472032;ERC-2010-AdG_20100224;/ERC-AG;UNIVERSITY COLLEGE LONDON;UK;;;"/PSE;/AER;/SPA";1;0;0;1;0;0 95532;258360;uTRUSTit;CLO;FP7-ICT;ICT-2009.1.4;FP7;Usable TRUST in the Internet of Things;2010-09-01;2013-12-31;;The Internet of Things (IoT) will connect a large number of communication and information systems. These systems will be part of everyday life in the same way mobile phones have become part of our lives. The information security properties of the IoT are often difficult to understand for its users, because they are hidden in pervasive systems and small devices manufactured by a large number of vendors. Trustworthiness, security functions and privacy implications are vast, and must be assessable to users and consumers.
The main focus of the uTRUSTit project lies in its objective to integrate the user directly in the trust chain, guaranteeing transparency in the underlying security and reliability properties of the IoT. The results of uTRUSTit enable system manufacturers and system integrators to express the underlying security concepts to users in a comprehensible way, allowing them to make valid judgements on the trustworthiness of such systems. Further, uTRUSTit's design guidelines on trust help the industry to implement the trust-feedback toolkit developed by uTRUSTit in a secure, usable and accessible way.
The uTRUSTit project will develop a cognitive model of user trust perception, its requirements, and its complete evaluation in simulation and end user trials.
The problem area will be approached with interdisciplinary requirements engineering, the extension of usability methodology, simulation of IoT environments in virtual reality, and rapid prototyping of IoT environments for end-user testing in usability labs.
The uTRUSTit consortium is composed of experienced security researchers, practitioners, and simulation and usability laboratories from different parts of Europe. It provides the expertise and experience needed to successfully solve the challenges of trust in the IoT.;3289859;2399506;FP7-ICT-2009-5;/CP;CURE CENTRUM FUR DIE UNTERSUCHUNG UND REALISIERUNG ENDBENUTZERORIENTIERTER INTERAKTIVER SYSTEME;AT;"SWEDEN CONNECTIVITY AB;NORSK REGNESENTRAL;TECHNISCHE UNIVERSITAET CHEMNITZ;SEARCH-LAB BIZTONSAGI ERTEKELO ELEMZO ES KUTATO LABORATORIUM KORLATOLT FELELOSSEGU TARSASAG;KATHOLIEKE UNIVERSITEIT LEUVEN";"SE;NO;DE;HU;BE";"/ICT;/INF";1;0;0;1;0;0 102612;295719;PALAEODESERTS;ONG;FP7-IDEAS-ERC;ERC-AG-ID1;FP7;Climate Change and Hominin Evolution in the Arabian Desert: Life and Death at the Cross-roads of the Old World;2012-03-01;2017-02-28;;"The evolutionary success of humans can be attributed to our ability to adapt to ever-changing environments. This reproductive and adaptive success is demonstrated by the 7 billion living humans, occupying nearly every corner of the globe. However, the expansion of humans is an evolutionarily recent development; fossil, genetic and archaeological evidence indicates that humans and our hominin ancestors frequently failed to adapt to climatic fluctuations, leading to demographic contractions and regional extinctions. Remarkably little is known about the history of these evolutionary successes and failures across vast regions of the world, including in the Arabian Desert - a critical biogeographical landbridge for hominins and other animals. Although poorly known, the Arabian Desert preserves spectacular Pleistocene and Holocene records, with considerable potential for elucidating evolutionary patterns and processes on a variety of spatial and temporal scales. The PALAEODESERTS project sets forth a series of testable hypotheses to address the relations between humid and arid climatic periods and population expansions, contractions and extinctions. To address the hypotheses a bold interdisciplinary approach is taken, combining information from palaeoenvironmental studies, palaeontology, geography, geochronology, animal and human genetics, archaeology, rock art studies and linguistics. Examination of hominin and animal population histories provides a comparative framework to assess when, why and how novel cultural behaviours provided survival benefits to hominins. The PALAEODESERTS project will have a profound effect on our understanding of Arabia’s place in the story of human evolution and, more broadly, on the relationship between environmental change, population history, and cultural innovations. This project is uniquely placed to understand our past and contextualise the present at a time when climate change is of considerable public and academic interest and concern.";2244350;2244350;ERC-2011-ADG_20110406;/ERC-AG;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;DE;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;UK;/SCI;1;0;0;1;0;0 89158;213592;CARMUSYS;ONG;FP7-PEOPLE;PEOPLE-2007-1-1-ITN;FP7;Carbohydrate Multivalent Systems as tools to study Pathogen interaction with DC-SIGN;2009-01-01;2012-12-31;;The importance of glycosciences in the development of biology and medicine and the central role played by chemistry in this process have recently been pointed out by ESF. However, it appears that exposure of young scientists in their training phase to the chemical biology of carbohydrates is still lacking. This multidisciplinary project intends to approach the design and synthesis of carbohydrate multivalent systems to be used as tools to study the interaction between carbohydrates and DC-SIGN (Dendritic Cell-Specific ICAM-3 Grabbing Non-integrin), a C-type lectin implicated in the recognition of pathogens and in some of the earliest stages of the infection process. Targeting pathogens at the earliest stages of infection, before cell penetration, is of crucial importance because it can result in a significant decrease of pathogen titre in the organism and therefore will facilitate the efficiency of current therapies. The role that DC-SIGN plays in the immune response through the interaction and recognition of pathogens leads to a very complex pathway of signalling cascade that could be modulated using these carbohydrate multivalent systems as effectors. Thus the studies we propose could provide the background for the design, selection and preparation of better antiviral drugs and could afford new insights to unravel the complex mechanisms of the immune system, thus opening a strategy to develop vaccines through the modulation of dendritic cells activity. To reach these goals, a highly interdisciplinary group of scientists (synthetic chemists, computational chemists, biochemists, immunologists, etc.) has been assembled, some of whom are already collaborating on the topic. The planned flow of information between laboratories and the network-wide training activities described in this proposal will create an unrivalled environment for training of young scientists in glycosciences.;3123720,43;3123720,43;FP7-PEOPLE-2007-1-1-ITN;/MC-ITN;AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS;ES;"DC4U;INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE;""FUNDACION PARA LA INVESTIGACION BIOMEDICA DEL HOSPITAL UNIVERSITARIO """"DOCE DE OCTUBRE"""""";anterio consult & research GmbH;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;VYSOKA SKOLA CHEMICKO-TECHNOLOGICKA V PRAZE;VERENIGING VOOR CHRISTELIJK HOGER ONDERWIJS WETENSCHAPPELIJK ONDERZOEK EN PATIENTENZORG;UNIVERSITE JOSEPH FOURIER GRENOBLE 1;INSTITUT PASTEUR;UNIVERSITA DEGLI STUDI DI MILANO;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS";"NL;FR;ES;DE;CZ;IT;UK";"/EMP;/SOC;/EDU";1;0;0;1;0;0 101128;289278;SPHINGONET;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-ITN;FP7;Sphingolipid homeostasis: from basic biology to applications;2012-02-01;2016-01-31;http://www.sphingonet-itn.eu/;SPHINGONET was inspired by a common vision of its partners on the training of researchers in the field of sphingolipid homeostasis and body-wide sphingolipid signaling networks using innovative technological approaches. Dysregulation of sphingolipid balances contributes to a broad range of pathological processes, spanning neurodegeneration, asthma, autoimmune disease, insuline resistance, obesity and cancer progression. Key to defining proper sites for therapeutic intervention is a comprehensive understanding of the mechanisms of sphingolipid homeostasis and how sphingolipid-mediated signaling pathways are interconnected. In spite of its many clinical implications, progress in this field is curbed by a lack of appropriate tools to monitor, quantify and manipulate sphingolipid pools in live cells. SPHINGONET’S training program is designed to close these gaps in knowledge and technology by transferring the complementary expertise of its partners to a future generation of scientists who will take a leading role in decoding the full regulatory potential of the sphingolipid signaling network and maximize its therapeutic use. By merging seven academic partners working at the forefront of sphingolipid, chemical and systems biology with three (pro)drug discovery-oriented SMEs, SPHINGONET will create a challenging interdisciplinary and clinically-relevant research environment with ample opportunities for structuring industrial projects, commercial exploitation of results, entrepreneurship and complementary education adapted to the personal needs. Thus, SPHINGONET will provide its trainees with a rounded education that, besides enhancing their career perspectives, will enable them to choose a career path in Europe’s academia or industry, and be successful at it while retaining ties between both these bodies.;3336194,94;3336194,94;FP7-PEOPLE-2011-ITN;/MC-ITN;UNIVERSITAET OSNABRUECK;DE;"UNIVERSITE DE GENEVE;WEIZMANN INSTITUTE OF SCIENCE;EUROPEAN MOLECULAR BIOLOGY LABORATORY;ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;Dualsystems Biotech AG;UNIVERSITEIT UTRECHT;UNIVERSITY COLLEGE LONDON;INTANA BIOSCIENCE GMBH";"CH;IL;DE;UK;NL";"/LIF;/SCI";1;0;0;1;0;0 86756;220833;ANAVACO;ONG;FP7-PEOPLE;PEOPLE-2007-4-1.IOF;FP7;Analysis of natural variation for cold tolerance in the model plant species Arabidopsis thaliana;2008-05-22;2011-05-21;;The identification of the genetic variants underlying adaptive traits constitutes one of the major challenges for modern biology. In this proposal we focus on the ability of plants to tolerate low temperatures. The molecular basis of cold tolerance has been widely investigated in crop species since freezing temperatures can severely affect quality, yield and production. Through the use of the model plant species Arabidopsis thaliana a dramatic increase in the understanding of the genetic mechanisms underlying cold tolerance was achieved. However, many questions remain still open with regard to the nature of the genes involved in the response of plants to cold temperatures. In this project an original, interdisciplinary strategy will be adopted to address naturally occurring variation for cold tolerance in A. thaliana. First, with the aim of identifying the genes underlying variation for cold tolerance in A. thaliana, association mapping will be performed, making use of a set of 1300 A. thaliana accessions, genotyped for 250.000 Single Nucleotide Polymorphisms. In contrast to classical linkage mapping, association mapping has the potential to identify single or a few genes. However, it is affected by population structure, which can eventually lead to a high rate of false positives. Therefore, F2 and F3 progenies will be designed, and used in classical linkage mapping to confirm that associations are due to linkage with causative polymorphisms rather than being spurious correlations due to population structure. Second, to elucidate the selective forces to which the loci identified in the association study have been submitted nucleotide variation will be analyzed at the loci as well as at their surrounding genomic regions and compared to the genome-wide polymorphism pattern. Finally, the candidate loci for cold tolerance identified through association mapping will be submitted to functional analyses in order to confirm their implication in cold tolerance.;236443,3;236443,3;FP7-PEOPLE-2007-4-1-IOF;/MC-IOF;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;DE;;;"/SCI;/COO";1;0;0;1;0;0 107917;326780;Monetized justice;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IEF;FP7;Monetized justice. The new meaning of penal fines in consumer societies;2013-08-01;2014-08-31;;At the core of the project is the elaboration and presentation of one innovative concept: monetized justice. It aims to understand the social functions and consequences of the most important alternative to imprisonment in Western societies in times of the collapse of the Welfare state and the transformation of social control forms: the penal fine analysed within the most general context of financial penalties . In a monetized society, in which money is increasingly available and all objects can be exchanged for money, fine takes on a different meaning, which will be investigated in the context of this project, taking into account that fine is the only form of penal sanction where the burden need not be borne by the wrongdoer. In this respect, the concept monetized justice explores the view that contemporary penal governance is less concerned with disciplining individuals and more concerned with regulating distributions and flows of behaviours and the problems ands costs linked with these. To this end, the project will take an interdisciplinary approach between the doctrines for criminal justice, criminology and criminal policy, assigning a relevant role to sociology and offering a multidisciplinary perspective.;121213,3;121213,3;FP7-PEOPLE-2012-IEF;/MC-IEF;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;DE;;;/SCI;1;0;0;1;0;0 107159;310584;NANOREG;ONG;FP7-NMP;NMP.2012.1.3-3;FP7;A common European approach to the regulatory testing of nanomaterials;2013-03-01;2017-02-28;;"The innovative and economic potential of Manufactured Nano Materials (MNMs) is threatened by a limited understanding of the related EHS issues. While toxicity data is continuously becoming available, the relevance to regulators is often unclear or unproven. The shrinking time to market of new MNM drives the need for urgent action by regulators. NANoREG is the first FP7 project to deliver the answers needed by regulators and legislators on EHS by linking them to a scientific evaluation of data and test methods. Based on questions and requirements supplied by regulators and legislators, NANoREG will: (i) provide answers and solutions from existing data, complemented with new knowledge, (ii) Provide a tool box of relevant instruments for risk assessment, characterisation, toxicity testing and exposure measurements of MNMs, (iii) develop, for the long term, new testing strategies adapted to innovation requirements, (iv) Establish a close collaboration among authorities, industry and science leading to efficient and practically applicable risk management approaches for MNMs and products containing MNMs. The interdisciplinary approach involving the three main stakeholders (Regulation, Industry and Science) will significantly contribute to reducing the risks from MNMs in industrial and consumer products. NANoREG starts by analysing existing knowledge (from WPMN-, FP- and other projects). This is combined with a synthesis of the needs of the authorities and new knowledge covering the identified gaps, used to fill the validated NANoREG tool box and data base, conform with ECHA's IUCLID DB structure. To answer regulatory questions and needs NANoREG will set up the liaisons with the regulation and legislation authorities in the NANoREG partner countries, establish and intensify the liaisons with selected industries and new enterprises, and develop liaisons to global standardisation and regulation institutions in countries like USA, Canada, Australia, Japan, and Russia.";49586318,23;10000000;FP7-NMP-2012-LARGE-6;/CP-IP;MINISTERIE VAN INFRASTRUCTUUR EN WATERSTAAT;NL;"BUNDESINSTITUT FUER RISIKOBEWERTUNG;NPL MANAGEMENT LIMITED;VYSOKA SKOLA BANSKA - TECHNICKA UNIVERZITA OSTRAVA;INSTITUTO TECNOLOGICO DEL EMBALAJE, TRANSPORTE Y LOGISTICA;COVESTRO DEUTSCHLAND AG;VENETO NANOTECH SOCIETA CONSORTILEPER AZIONI;AIT AUSTRIAN INSTITUTE OF TECHNOLOGY GMBH;ASOCIACION DE INVESTIGACION DE LAS INDUSTRIAS DE LA CONSTRUCCION;TURVALLISUUS JA KEMIKAALIVIRASTO;ASSOCIATION SAINT YVES;FUNDACION TEKNIKER;THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN;NEDERLANDSE ORGANISATIE VOOR TOEGEPAST NATUURWETENSCHAPPELIJK ONDERZOEK TNO;STIFTELSEN SINTEF;BUNDESANSTALT FUER ARBEITSSCHUTZ UND ARBEITSMEDIZIN;COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES;INSTITUT NATIONAL DE L ENVIRONNEMENT ET DES RISQUES INERIS;TEMAS AG TECHNOLOGY AND MANAGEMENT SERVICES;ISTITUTO SUPERIORE DI SANITA;Public Health England an Executive Agency of the Dept of Health;GEOCHEM RESEARCH BV;ECAMRICERT SRL;FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS;NORSK INSTITUTT FOR LUFTFORSKNING STIFTELSE;INSTITUTE OF OCCUPATIONAL MEDICINE;USTAV EXPERIMENTALNI MEDICINY AKADEMIE VED CESKE REPUBLIKY VEREJNA VYZKUMNA INSTITUCE;RISE RESEARCH INSTITUTES OF SWEDEN AB;INSTITUTE OF PUBLIC HEALTH OSTRAVA;UNIVERSITAET LEIPZIG;FUNDACION GAIKER;UNIVERSITY OF LEEDS;AGENZIA NAZIONALE PER LE NUOVE TECNOLOGIE, L'ENERGIA E LO SVILUPPO ECONOMICO SOSTENIBILE;Department of Health;UNIVERSIDAD DE LLEIDA;NORGES MILJO-OG BIOVITENSKAPLIGE UNIVERSITET;FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA;COMET BIOTECH AS;RIJKSINSTITUUT VOOR VOLKSGEZONDHEID EN MILIEU;CONSIGLIO NAZIONALE DELLE RICERCHE;BASF SE;BIONANONET FORSCHUNGSGESELLSCHAFT MBH;HERIOT-WATT UNIVERSITY;""NATIONAL CENTER FOR SCIENTIFIC RESEARCH """"DEMOKRITOS"""""";CENTRUM VOOR ONDERZOEK IN DIERGENEESKUNDE EN AGROCHEMIE - CODA;STORA ENSO OYJ;LABORATOIRE NATIONAL DE METROLOGIE ET D'ESSAIS;ARKEMA FRANCE;EIDGENOESSISCHES DEPARTEMENT DES INNERN;KAROLINSKA INSTITUTET;INSTITUTO DE SOLDADURA E QUALIDADE;INSTITUT PASTEUR DE LILLE FONDATION;ACONDICIONAMIENTO TARRASENSE ASSOCIACION;ENVICAT CONSULTING SPRL;UNIVERSITAT AUTONOMA DE BARCELONA;LUNDS UNIVERSITET;NANOTECHNOLOGY INDUSTRIES ASSOCIATION;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;LABORATORIO IBERICO INTERNACIONAL DE NANOTECNOLOGIA;AGENCE NATIONALE DE LA SECURITE SANITAIRE DE L ALIMENTATION DE L ENVIRONNEMENT ET DU TRAVAIL;DET NATIONALE FORSKNINGSCENTER FORARBEJDSMILJO;GENOK - SENTER FOR BIOSIKKERHET;STATENS ARBEIDSMILJOINSTITUTT;UNIVERSITETET I BERGEN;TYOTERVEYSLAITOS;UNIVERSITE DE NAMUR ASBL;INSTITUT NATIONAL DE RECHERCHE ET DE SECURITE POUR LA PREVENTION DES ACCIDENTS DU TRAVAIL ET DES MALADIES PROFESSIONNELLES ASSOCIATION;UPM-KYMMENE OYJ;STICHTING WAGENINGEN RESEARCH;CHALMERS TEKNISKA HOEGSKOLA AB;JRC -JOINT RESEARCH CENTRE- EUROPEAN COMMISSION";"DE;UK;CZ;ES;IT;AT;FI;FR;IE;NL;NO;CH;EL;SE;BE;PT;DK";/SCI;1;0;0;1;0;0 100612;289941;FLIACT;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-ITN;FP7;Systems neuroscience of Drosophila: from genes to circuits to behaviour;2012-01-01;2015-12-31;;"Understanding how the brain works represents one of the greatest challenges in modern science. This question embraces mechanisms spanning multiple levels of description, from genes to biochemical pathways, from neurons to circuits, from circuit activities to adaptive behaviours. The goal of the FLiACT programme is to train young researchers in the concepts and techniques necessary to study integrated brain functions. FLiACT will create a unique pan-European training network interconnecting 8 academic partners and 3 SMEs specialised in complementary fields of research from molecular and behavioural neurogenetics to electrophysiology, bioengineering and applied biomedicine. To facilitate knowledge transfer across the network, FLiACT will focus on one model organism, the fruit fly Drosophila melanogaster. During the last decades, Drosophila has become a premier system to clarify the molecular and cellular logic of perception and cognition. It has also emerged as a powerful model to study the genetic bases of neurodegenerative diseases affecting humans. The fly community can now capitalize on an unprecedented toolkit to probe the function of neural circuits in vivo and to interfere with their functions in a highly controlled manner. We aim to provide a group of neuroscientists with enough momentum to combine all these tools in a unifying framework. In collaborative and personalised research projects, FLiACT fellows will seek to elucidate how neural circuit computation controls behaviour and how circuit-function relationships are genetically encoded. FLiACT will organise a series of interdisciplinary workshops on neurogenetics, neuroanatomy, neuroimaging and behavioural analysis and transferable skills. We will maximize the impact of our initiative by opening all workshops and conferences to the neuroscience community. FLiACT intends to have a timely structuring effect in a strategic area for European research and technology: systems neuroscience.";3152307,02;3152307,02;FP7-PEOPLE-2011-ITN;/MC-ITN;FUNDACIO CENTRE DE REGULACIO GENOMICA;ES;"JOHANNES GUTENBERG-UNIVERSITAT MAINZ;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;PEIRA;VIB;DIGITAL CELL IMAGING LABS BVBA;Brainwave-Discovery Limited;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;UNIVERSITE DE FRIBOURG;FUNDACAO D. ANNA SOMMER CHAMPALIMAUD E DR. CARLOS MONTEZ CHAMPALIMAUD;FORSCHUNGSINSTITUT FUR MOLEKULARE PATHOLOGIE GESELLSCHAFT MBH";"DE;BE;UK;FR;CH;PT;AT";"/LIF;/SCI";1;0;0;1;0;0 185997;623994;ProteinFED;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IOF;FP7;Towards Femtosecond Electron Diffraction of Proteins;2014-04-01;2017-03-31;;'Proteins are highly dynamic machines, perfectly engineered by nature to fulfil their dedicated function like e.g. catalysis of chemical reactions or signalling processes. Crystallography and ultrafast spectroscopy techniques gave fundamental insights to develop a time-resolved picture of biological function. However experimental tools to study ultrafast protein dynamics with atomic and ultrafast time resolution in the same experiment to fully access and describe the structure-function correlation of biochemical processes have been lacking so far. The ambitious goal of the proposed project is to explore sample preparation strategies for the test systems Bacteriorhodopsin and Myoglobin/Hemoglobin to extend the new technology 'Femtosecond electron diffraction' (FED) to studies of proteins. FED is a method complementary to ultrafast studies using new X-ray free electron laser sources. The main challenge for this study is sufficient sample preparation and development. For this the group of Oliver P. Ernst at University of Toronto, a world-known structural biologist specialized in rhodopsin research, acts as outgoing host. In the group of R. J. Dwayne Miller, acting as host, at Max-Planck-Institute for Structure and Dynamics of Matter, Hamburg, the femtosecond electron diffraction experiments will be carried out, grounded on their expertise as the world-leading group in developing ultrabright electron sources on par with the European XFEL and inventors of the FED technology. The researcher Henrike M. Müller-Werkmeister is the perfect candidate for this extremely interdisciplinary project, as biochemist by training and experienced in measurements of ultrafast biomolecular dynamics using multidimensional laser spectroscopy.';242049,6;242049,6;FP7-PEOPLE-2013-IOF;/MC-IOF;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;DE;;;/LIF;1;0;0;1;0;0 101336;290002;ADVANCE;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-ITN;FP7;ADenoViruses as novel clinical treatments;2012-04-01;2016-03-31;;ADVance is designed to integrate 8 leading academic centres and 4 private companies under a single umbrella to create an opportunity to train young scientists in adenovirus (AdV) research. Our full partners and industrial partners represent internationally leading academic centres of excellence in key facets of research into the basic biology of AdV and their application as vectors for clinical protocols in cancer, cardiovascular disease and vaccination that is unique as a training opportunity. Our academic and private sector full partners represent a key areas critical to improved understanding of adenovirus biology and development of key underpinning technology for translational AdV research at the highest level and will create a training opportunity of the highest calibre. The training components are further complemented by our associated partners EASCO that will integrate into ADVance a broad interdisciplinary training and dissemination program. This will ensure the very best training in scientific and key non-scientific skills for each recruited ESRs and ERs. We have also recruited Glen Nemerow as a visiting researcher for his depth of understanding and experience in AdV research over many years. ESR will benefit extensively from the complementarity between the host institutes and strength in depth in training for future careers as well as elevated long term research links for host institutes and companies in the longer term. The network research training is based on a group of well defined and highly innovative research projects applying state-of-the-art methodologies. ADVance will allow lasting collaborations between partners, with and extensive plan of inter-partners secondments of ESR/ERs, which will and create a critical mass of focused adenovirus biologists and translationnal scientists and allow our recruited young researchers to start an excellent career in this field;3861450;3861450;FP7-PEOPLE-2011-ITN;/MC-ITN;UNIVERSITY OF GLASGOW;UK;"PSIOXUS THERAPEUTICS;MAGYAR TUDOMANYOS AKADEMIA AGRARTUDOMANYI KUTATOKOZPONT;TARGOVAX OY;UMEA UNIVERSITET;UNIVERSITAT ZURICH;BATAVIA BIOSCIENCES BV;JANSSEN VACCINES & PREVENTION BV;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;ITA-SUOMEN YLIOPISTO;FUNDACIO INSTITUT D'INVESTIGACIO BIOMEDICA DE BELLVITGE;MAGYAR TUDOMANYOS AKADEMIA ALLATORVOS-TUDOMANYI KUTATOINTEZETE";"UK;HU;FI;SE;CH;NL;FR;ES";"/LIF;/SCI";1;0;0;1;0;0 187778;623543;GBMTARGET;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IEF;FP7;Targeting Glioblastoma Signalling;2014-03-01;2016-02-29;;"This project will establish a computational strategy which exploits polypharmacology to identify drug targets in biological systems implicated in cancer. The value of our polyphamacology platform will be tested by application to glioblastoma multiforme, a deadly brain cancer. The aim will be to identify multiple targets in protein networks linked to glioblastoma to thereby enable repositioning of drugs against that cancer. The novelty of the work will lie in its use of protein domain structure data to link known and putative drug compounds to biological networks. The project is proposed as an interdisciplinar and intersectoral research: (i) It will be developed on the basis of the domain structure resources and expertise in the host group of Prof. Orengo at University College London (UCL), and the compound-target libraries and drug discovery expertise within the pharmaceutical company GlaxoSmithKline, which will be a seconded host institution; (ii) it will benefit from the expertise in protein-ligand interactions developed in the group of Prof. Janet Thornton and the group of Prof. John Overington at the European Bioinformatics Institute; (iii) the experimental testing of putative drug compounds will be undertaken in collaboration with the group of Dr Matilda Katan-Muller at UCL and the group of Prof David Selwood at UCL.";309235,2;309235,2;FP7-PEOPLE-2013-IEF;/MC-IEF;UNIVERSITY COLLEGE LONDON;UK;;;;1;0;0;1;0;0 92899;226354;HERMIONE;ONG;FP7-ENVIRONMENT;ENV.2008.2.2.1.2.;FP7;Hotspot Ecosystem Research and Man's Impact on European seas;2009-04-01;2012-09-30;http://www.eu-hermione.net/;The HERMIONE project is designed to make a major advance in our knowledge of the functioning of deep-sea ecosystems and their contribution to the production of goods and services. This will be achieved through a highly interdisciplinary approach (including biologists, ecologists, microbiologists, biogeochemists, sedimentologists, physical oceanographers, modelers and socio-economists) that will integrate biodiversity, specific adaptions and biological capacity in the context of a wide range of highly vulnerable deep-sea habitats. Gaining this understanding is crucial, because these ecosystems are now being affected by climate change and impacted by man through fishing, resource extraction, seabed installations and pollution. To design and implement effective governance strategies and management plans we must understand the extent, natural dynamics and interconnection of ocean ecosystems and integrate socio-economic research with natural science. The study sites include the Arctic, North Atlantic and Mediterranean and cover a range of ecosystems including cold-water corals, canyons, cold and hot seeps, seamounts and open slopes and deep-basins. The project will make strong connections between deep-sea science and user needs. HERMIONE will enhance the education and public perception of the deep-ocean issues also through some of the major EU aquaria. These actions, together with GEOSS databases that will be made available, will create a platform for discussion between a range of stakeholders, and contribute to EU environmental policies.;10982142,33;7998955;FP7-ENV-2008-1;/CP-IP;NATURAL ENVIRONMENT RESEARCH COUNCIL;UK;"HAVFORSKNINGSINSTITUTTET;INSTITUTO HIDROGRAFICO;UNIVERSITETET I TROMSOE;THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN;SENCKENBERG GESELLSCHAFT FUR NATURFORSCHUNG;UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6;FRIEDRICH-ALEXANDER-UNIVERSITAET ERLANGEN NUERNBERG;NATIONAL UNIVERSITY OF IRELAND GALWAY;WCMC LBG;THE SCOTTISH ASSOCIATION FOR MARINESCIENCE LBG;KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW;UNIVERSITEIT GENT;Median SCP;HELLENIC CENTRE FOR MARINE RESEARCH;STICHTING NIOZ, KONINKLIJK NEDERLANDS INSTITUUT VOOR ONDERZOEK DER ZEE;COSTA EDUTAINMENT S.P.A;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;JACOBS UNIVERSITY BREMEN GGMBH;AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS;ALFRED-WEGENER-INSTITUT HELMHOLTZ-ZENTRUM FUR POLAR- UND MEERESFORSCHUNG;UNIVERSITAET BREMEN;UNIVERSIDADE DE AVEIRO;National Marine Aquarium Ltd.;CONSIGLIO NAZIONALE DELLE RICERCHE;HERIOT-WATT UNIVERSITY;UNIVERSITY OF SOUTHAMPTON;UNIVERSITAT DE BARCELONA;CONSORZIO NAZIONALE INTERUNIVERSITARIO PER LE SCIENZE DEL MARE ASSOCIAZIONE;LEIBNIZ-INSTITUT FUER MEERESWISSENSCHAFTEN AN DER UNIVERSITAET KIEL;INSTITUT FRANCAIS DE RECHERCHE POUR L'EXPLOITATION DE LA MER;THE UNIVERSITY OF LIVERPOOL;P.P. SHIRSHOV INSTITUTE OF OCEANOLOGY OF RUSSIAN ACADEMY OF SCIENCES;PANEPISTIMIO THESSALIAS;ArchimediX, Möckl & Munzel GbR;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK;GOETEBORGS UNIVERSITET;Universidade dos Açores;UNITED NATIONS ENVIRONMENT PROGRAMME;CARDIFF UNIVERSITY";"NO;PT;UK;DE;FR;IE;DK;NL;BE;ES;EL;IT;RU;SE;KE";/SEA;1;0;0;1;0;0 101555;287589;MICRO B3;ONG;FP7-KBBE;OCEAN.2011-2;FP7;Marine Microbial Biodiversity, Bioinformatics and Biotechnology;2012-01-01;2015-12-31;http://www.microb3.eu/;"Micro B3 will develop innovative bioinformatic approaches and a legal framework to make large-scale data on marine viral, bacteria; archaeal and protists genomes and metagenomes accessible for marine ecosystems biology and to define new targets for biotechnological applications. Micro B3 will build upon a highly interdisciplinary consortium of 32 academic and industrial partners comprising world-leading experts in bioinformatics, computer science, biology, ecology, oceanography, bioprospecting and biotechnology, as well as legal aspects. Micro B3 is based on a strong user- and data basis from ongoing European sampling campaigns to long-term ecological research sites. For the first time a strong link between oceanographic and molecular microbial research will be established to integrate global marine data with research on microbial biodiversity and functions. The Micro B3 Information System will provide innovative open source software for data-processing, -integration, -visualisation, and -accessibility. Interoperability will be the key for seamless data transfer of sequence and contextual data to public repositories. Micro B3 will allow taking full advantage of current sequencing technologies to efficiently exploit large-scale sequence data in an environmental context. Micro B3 will create integrated knowledge to inform marine ecosystems biology and modelling. Moreover, it will facilitate detecting candidate genes to be explored by targeted laboratory experiments for biotechnology and for assigning potential functions to unknown genes. Micro B3 will develop clear IP agreements for the protection and sustainable use of pre-competitive microbial genetic resources and their exploitation in high potential commercial applications. To underline the translational character of Micro B3, outreach and training activities for diverse stakeholders are planned as well as an Ocean Sampling Day to transparently make project results accessible and gain valuable user feedback.";11496409,35;8987491;FP7-OCEAN-2011;/CP-IP;JACOBS UNIVERSITY BREMEN GGMBH;DE;"BIOILIBERIS RESEARCH AND DEVELOPMENT SL;Ribocon GmbH;EUROPEAN MOLECULAR BIOLOGY LABORATORY;COMMISSION INTERNATIONALE POUR L'EXPLORATION SCIENTIFIQUE DE LA MER MEDITERRANEE (CIESM);HELLENIC CENTRE FOR MARINE RESEARCH;COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES;TURKIYE BILIMSEL VE TEKNOLOJIK ARASTIRMA KURUMU;STAZIONE ZOOLOGICA ANTON DOHRN;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;UNIVERSITE CATHOLIQUE DE LOUVAIN;MATIS OHF;WESNIGK JOHANNA B;UNION INTERNATIONALE POUR LA CONSERVATION DE LA NATURE ET DE SES RESSOURCES;AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS;PHARMAMAR, S.A.;ALFRED-WEGENER-INSTITUT HELMHOLTZ-ZENTRUM FUR POLAR- UND MEERESFORSCHUNG;INTERNATIONAL COUNCIL FOR THE EXPLORATION OF THE SEA;UNIVERSITAET BREMEN;DRUSTVO ZA USLUGI I TRGOVIJA INTERWORKS UVOZ-IZVOZ DOOEL BITOLA;CONSIGLIO NAZIONALE DELLE RICERCHE;VIB;INSTITUT FRANCAIS DE RECHERCHE POUR L'EXPLOITATION DE LA MER;RIJKSUNIVERSITEIT GRONINGEN;MARIENE INFORMATIE SERVICE MARIS BV;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;MARINE BIOLOGICAL ASSOCIATION OF THE UNITED KINGDOM;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;VLAAMS INSTITUUT VOOR DE ZEE VZW;BANGOR UNIVERSITY;UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK;BIO-PRODICT BV";"ES;DE;MC;EL;FR;TR;IT;BE;IS;CH;DK;MK;NL;UK;IE";/ENV;1;0;0;1;0;0 91769;241118;BABYLON;ONG;FP7-IDEAS-ERC;ERC-SG-SH6;FP7;By the Rivers of Babylon: New Perspectives on Second Temple Judaism from Cuneiform Texts;2009-09-01;2015-08-31;;"This project has the potential to radically change current understanding of cultic and social transformation in the post-exilic temple community of Jerusalem (c. 6th-4th centuries BCE), an important formative phase of ancient Judaism. “BABYLON” draws on recent, ground-breaking advances in the study of cuneiform texts to illuminate the Babylonian environment of the Judean exile, the socio-historical context which gave rise to the transformative era in Second Temple Judaism. In particular, these new data show that the parallels between Babylonian and post-exilic forms of cultic and social organization were substantially more far-reaching than presently recognized in Biblical scholarship. “BABYLON” will study the extent of these similarities and explore the question how Babylonian models could have influenced the restoration effort in Jerusalem. This goal will be achieved through four sub-projects. P1 will study the social dynamics and intellectual universe of the Babylonian priesthood. P2 will finalize the publication of cuneiform archives of Babylonian priests living in the time of the exile. P3 will identify the exact areas of change in the post-exilic temple community of Jerusalem. P4, the synthesis, will draw from each of these sub-projects to present a comparative study of the Second Temple and contemporary Babylonian models of cultic and social organization, and to propose a strategy of research into the possible routes of transmission between Babylonia and Jerusalem. The research will be carried out by three team members: the PI (P1 and P4), a PhD in Assyriology (P2) and a post-doctoral researcher in Biblical Studies specialized in the Second Temple period (P3 and P4). The participation of the wider academic community will be invited at two moments in the course of the project, in the form of a workshop and an international conference. “BABYLON” will adopt an interdisciplinary approach by bringing together Assyriologists and Biblical scholars for a much-needed dialogue, thereby exploding the artificial boundaries that currently exist in the academic landscape between these two fields.";1200000;1200000;ERC-2009-StG;/ERC-SG;UNIVERSITEIT LEIDEN;NL;"VERENIGING VOOR CHRISTELIJK HOGER ONDERWIJS WETENSCHAPPELIJK ONDERZOEK EN PATIENTENZORG;UNIVERSITY COLLEGE LONDON";"NL;UK";"/SCI;/SOC";1;0;0;1;0;0 105428;316716;HIMR;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-ITN;FP7;Ultra-High Field Magnetic Resonance Imaging;2012-11-01;2016-10-31;;The High field Magnetic Resonance (HiMR) Initial Training Network aims to train the future leaders of academic and industrial research in the fundamental science and novel applications of ultra-high field (UHF) in vivo magnetic resonance (MR), in order to address an increasing and currently unmet demand from academia and industry for such specialists. The highly complex and multi-faceted nature of UHF MR means that excellent training can only be provided by immersing ESRs in an environment that integrates different research areas, sectors and groups. The HiMR ITN is centred on a cutting edge, multidisciplinary research program that exploits the complementarities of the participants. This research programme is organised into four themes each focused on a crucial area of development of UHF. The first focuses on improved structural imaging, advancing our understanding of the origins of contrast in MRI scans and developing non-invasive biomarkers for multiple sclerosis. The second theme is centred upon exploiting UHF to develop ultra-high resolution functional MRI (fMRI) which will be very important in basic neuroscience research. It also aims to make fMRI more quantitative, thus encouraging its uptake in the clinic. The third theme aims to exploit the enhanced sensitivity of MR spectroscopy (MRS) at UHF in developing highly specific biomarkers. The final theme will develop novel hardware for both research and in the clinic, and methods of monitoring and correcting motion which limits in-vivo MR resolution. Finally the HiMR ITN will provide a unique opportunity to measure safety outcomes over a large group of workers. The proposed interdisciplinary and intersectoral training program, embedded in this research program, will provide a platform for training ESRs to become specialists in UHF MR, whilst also furnishing them with experience of a broad range of work environments, experimental techniques and theoretical knowledge relevant to the full range of in vivo MR.;3597440;3597440;FP7-PEOPLE-2012-ITN;/MC-ITN;THE UNIVERSITY OF NOTTINGHAM;UK;"OTTO-VON-GUERICKE-UNIVERSITAET MAGDEBURG;STICHTING KATHOLIEKE UNIVERSITEIT;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;UNIVERSITA DI PISA;UNIVERSITAIR MEDISCH CENTRUM UTRECHT;UNIVERSITAETSKLINIKUM ESSEN;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD";"DE;NL;IT;UK";/LIF;1;0;0;1;0;0 97261;261982;SHARE_M4;ONG;FP7-INFRASTRUCTURES;INFRA-2010-1.1.2;FP7;Multinational Advancement of Research Infrastructures on Ageing;2011-01-01;2014-12-31;;"This proposal includes all tasks that are essential to maintain the European added value of the Survey of Health, Ageing and Retirement in Europe (SHARE) and to keep the 16 national surveys well integrated. It complements the national financing mode of data collection as result of the ESFRI process by keeping its centrifugal forces in bounds. It will keep up our excellence in service provision as well as in science by: 1. Fostering the culture of cooperation between designers and users of SHARE by organizing user conferences, offering specialized training courses for users and interviewers, expanding web services and developing standards and procedures within the network that will make more efficient use of the research infrastructure. 2. Improving the multinational services for users in EU member countries, associated countries and third countries by a more efficient centralized data base management that will provide detailed synopses and concordances across member countries. We will coordinate this work with our sister surveys in the UK, US, China, India, Japan, Korea and Thailand, thereby providing a platform for global access to ageing data. 3. Pushing the state-of-the-art in interdisciplinary panel construction further such that SHARE will maintain its status as a leading edge research infrastructure. The project will leverage our research on response behaviour to minimize attrition; it will develop a multi-mode interviweing facility tailored to the 50\ in order to reduce survey costs; it will develop innovative questionnaire modules on biomarkers, physical health, social networks, pension claims, time use and nutrition that will keep SHARE at the forefront of empirical science; and, with the help of EUROMOD, it will harmonizes income concepts across EU-surveys, notably EU-SILC in order to facilitate the measurement of material well-being in times of rapid demographic change with its complex implications for old-age income provision.";7663671,88;5499991,81;FP7-INFRASTRUCTURES-2010-1;/CP-CSA-Infra;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;DE;"UNIVERSITE PARIS DAUPHINE;UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN;STICHTING CENTERDATA;UNIVERSITAET MANNHEIM;UNIVERSITA DEGLI STUDI DI PADOVA;UNIVERSITA CA' FOSCARI VENEZIA;UNIVERSITY OF ESSEX;INSTITUT DE RECHERCHE ET DOCUMENTATION EN ECONOMIE DE LA SANTE ASSOCIOATION;SYDDANSK UNIVERSITET;NARODOHOSPODARSKY USTAV AKADEMIE VED CESKE REPUBLIKY VEREJNA VYZKUMNA INSTITUCE;STICHTING KATHOLIEKE UNIVERSITEIT BRABANT;THE HEBREW UNIVERSITY OF JERUSALEM;ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM;FUNDACJA CENTRUM ANALIZ EKONOMICZNYCH";"FR;IE;NL;DE;IT;UK;DK;CZ;IL;PL";"/SCI;/SOC;/MED";1;0;0;1;0;0 106752;317221;MEDOW;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-ITN;FP7;Multi-terminal DC grid for offshore wind;2013-04-01;2017-03-31;http://www.medow.engineering.cf.ac.uk/;"A DC grid based on multi-terminal voltage-source converter is a newly emerging technology, which is particularly suitable for the connection of offshore wind farms. Multi-terminal DC grids will be the key technology for the European offshore SuperGrid. In this proposal, DC power flow, DC relaying protection, steady state operation, dynamic stability, fault-ride through capability, and impacts of DC grids on the operation of AC grids and power market will be studied. Systematic comparison of DC grid topologies and stability control strategies will be carried out. DC grids for offshore wind power transmission and onshore AC grid interconnection will be investigated. Operation and control will be evaluated using various simulation platforms and experimental test rigs. The achievements from the project will greatly contribute to integrating offshore wind power into the onshore AC grids in European countries and for the European Super Grid. The MEDOW consortium involves 11 partners (5 universities and 6 industrial organisations). Each institution in the consortium contributes various expertise on the manufacturing, design, operation, and control of multi-terminal DC grids. Three visiting scientists of outstanding international stature will be appointed to further strengthen the training capacity and quality of MEDOW. This project will recruit 12 early-stage researchers (ESRs) and 5 experienced researchers (ERs). These researchers will receive interdisciplinary and intersectoral trainings in different countries to improve career opportunities. Research results will be disseminated through publications, intellectual properties, and direct application in the industries. MEDOW offers a development path to researchers across Europe in the area of DC grids, in addition to fostering greater ties between industry and academia in this key development area.";3925537;3925537;FP7-PEOPLE-2012-ITN;/MC-ITN;CARDIFF UNIVERSITY;UK;"ALSTOM WIND S.L;EFACEC ENGENHARIA E SISTEMAS SA;UNIVERSITAT POLITECNICA DE CATALUNYA;ALSTOM RENOVABLES ESPA?A S.L.;ELIA SYSTEM OPERATOR;CHINA ELECTRIC POWER RESEARCH INSTITUTE (SEAL) SOE;EFACEC ENERGIA - MAQUINAS E EQUIPAMENTOS ELECTRICOS SA;DANMARKS TEKNISKE UNIVERSITET;UNIVERSIDADE DO PORTO;CONTROL INTEL-LIGENT DE L'ENERGIA SCCL;KATHOLIEKE UNIVERSITEIT LEUVEN";"ES;PT;BE;CN;DK";/LIF;1;0;0;1;0;0 92946;237956;EDU-GLIA;ONG;FP7-PEOPLE;FP7-PEOPLE-ITN-2008;FP7;Innovative Techniques and Models to Study Glia-Neuron Interactions;2009-09-15;2013-09-14;;It became evident over the last 20 years that glial cells are involved in virtually every aspect of nervous system function. Neurons and glia exchange chemical signals that are essential for the normal function of the nervous system, and are crucial in disease. Recently it was discovered that glial cells also act as neural stem cells both in early development and adulthood, and in synapse formation. This rapid progress in glia research generated not only many new insights but also numerous new questions, and it became obvious that to deal with the complexity of glia-neuron interactions and to formulate new concepts in the field, we need novel experimental paradigms and methodologies. The EdU-GLIA network is aimed at equipping young researchers with the most advanced skills knowledge in glial cell research, in order to generate a new generation of scientists dedicated to resolving open questions of glia-neuron interactions. We will offer young investigators high quality interdisciplinary projects that will be individually tailored and each will be supervised by two mentors. Our team of supervisors consists of leading experts in the field, including an industrial partner. EdU-GLIA is based upon current original and promising research models ranging from basic science to clinical application, and on the most advanced and sophisticated research techniques. To complement the research projects, we will offer the young scientists a rich selection of courses, workshops, guest lectures, and symposia. This program will not only provide insights into research techniques and paradigms complementary to the individual projects, but will also strengthen professional skills such as writing papers, presenting data, and ethical conduct, enhancing the career prospects of the fellows. In summary, the main objective of EdU-GLIA is to train promising young researchers for careers in basic as well as in translational research, including clinical application and industry.;3285553,81;3285553,81;FP7-PEOPLE-ITN-2008;/MC-ITN;EBERHARD KARLS UNIVERSITAET TUEBINGEN;DE;"TATAA BIOCENTER AB;UNIVERSITY OF PORTSMOUTH HIGHER EDUCATION CORPORATION;INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE;THE UNIVERSITY OF MANCHESTER;HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;USTAV EXPERIMENTALNI MEDICINY AKADEMIE VED CESKE REPUBLIKY VEREJNA VYZKUMNA INSTITUCE;UNIVERSITAET LEIPZIG;HADASSAH MEDICAL ORGANIZATION;GOETEBORGS UNIVERSITET;UNIVERZA V LJUBLJANI;UNIVERSITAT DES SAARLANDES";"SE;UK;FR;DE;CZ;IL;SI";"/SCI;/EDU";1;0;0;1;0;0 98950;268897;GENEMIT;ONG;FP7-IDEAS-ERC;ERC-AG-LS1;FP7;Regulation of gene expression in mammalian mitochondria;2011-05-01;2016-04-30;;The mitochondrial network produces the bulk part of the energy mammalian cells need through the oxidative phosphorylation process. The importance of mitochondria is underscored by the fact that deficient oxidative phosphorylation causes a wide number of genetic diseases. It is also heavily implicated in age-associated disease and ageing. Expression of mammalian mtDNA is of key importance for maintaining mitochondrial oxidative phosphorylation but studies of the poorly understood regulation of mammalian mitochondrial gene expression offer substantial experimental challenges. In the late 1990s, we felt that the challenges associated with understanding mammalian mtDNA gene expression could only be tackled by a broad interdisciplinary scientific approach. We therefore started collaboration between the Larsson (expertise in mouse genetics, in vivo physiology and cell biology) and Gustafsson laboratories (expertise in biochemistry, recombinant in vitro systems, structural biology) that has been ongoing for more than a decade. The success of this collaborative effort is documented by many joint publications in high-profile journals. Most importantly, we have together molecularly defined the basal mtDNA transcription initiation machinery and discovered a novel repressor, MTERF3, of mtDNA transcription. In this proposal, we present a series of unpublished results showing quite unexpected complexity in the regulation of mtDNA expression. An important part of our proposed work will be to establish how the different levels of regulation of mtDNA gene expression communicate to achieve a coordinated response to physiological stimuli.;3110000;3110000;ERC-2010-AdG_20100317;/ERC-AG;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;DE;GOETEBORGS UNIVERSITET;SE;"/BIO;/LIF";1;0;0;1;0;0 97582;247627;LIPAUGUS;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IRSES;FP7;Control of reproductive behaviors in an equatorial sub-oscine bird: Implication for biodiversity studies;2010-03-01;2014-02-28;;Although birds are the best studied vertebrate group, most studied species are endemic to the temperate zones while about half of all bird species life in the tropics. Further, among the tropical species many belong to the so-called sub-oscine passerines while the temperate zones are dominated by their sister group, the oscines or songbirds. The knowledge of the biodiversity of reproduction mechanisms of tropical species including the sub-oscines is essential to understand the generality of behavioral mechanisms derived from temperate zone species and required for conservation efforts. In an interdisciplinary longitudinal approach we study the reproductive behavior of a prominent tropical bird, the sub-oscine Lipaugus vociferans (screaming piha), the voice of the Amazon that inhabits most lowland forest of the Amazon basin. In the obstructed environment of the raining forest, reproductive success depends on vocalization. Male pihas sing in a chorus to achieve group precision required to attract females. Despite such complicated singing, the songs of the screaming piha are thought to be innate since this species belongs to the sub-oscines while the songs of related songbirds are learned. In relation, sub-oscines are thought to lack particular hormone-sensitive brain region that control vocal learning and control the seasonal singing of temperate songbirds. However, not only requires the chorus singing of the piha precision, their vocal performance is clearly seasonal. The study of reproductive behaviors such as vocalizations in a sub-oscine species near the equator delivers insights in (1) the environmental Zeitgeber(s) that synchronize reproductive behaviors in the tropics, (2) the endocrine factors that translate the external Zeitgeber into neuroendocrine mechanisms that facilitate vocal courtship and (3) the mechanisms of vocal learning of sub-oscines.;171000;171000;FP7-PEOPLE-2009-IRSES;/MC-IRSES;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;DE;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FR;"/SCI;/EDU;/ITT";1;0;0;1;0;0 110974;324400;HTP-GLYCOMET;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IAPP;FP7;Methods for high-throughput glycoproteomic analysis;2013-11-01;2017-10-31;;The main aim of the HTP-GlycoMet proposal is to develop technologies, which will enable high-throughput analysis of glycosylation of individual proteins from body fluids and cell membranes and apply them to understand some key processes in immunity and infections. Glycan analysis is extremely demanding from both technological and conceptual aspect and (beside one study performed by partners in this proposal) large-scale studies of glycosylation of individual proteins were not attempted previously. However, we are confident that by successfully combining complementary expertise in the (i) production of specialised monolithic chromatographic tools for high-throughput fractionation of complex biological fluids (BIA-SEP), (ii) purification of proteins from body fluids and membrane proteins (UNI-RI), (iii) high-throughput glycomic analysis by use of chromatography (Genos) and multiplexed capillary gel electrophoresis (MPI) and (iv) expertise in the field of viral immunology (MEDRI) we can achieve significant progress in this direction. All our partners are recognized leaders who already made significant progress beyond the state of the art in their respective fields. Through HTP-GlycoMet project we will organise secondments on all levels (MER, ER, ESR) to capitalize on synergistic effects of this interdisciplinary and transnational collaboration. In addition to the generation of new knowledge and the development of new innovative technologies, we will also achieve significant transfer of knowhow between academic and industrial partners. Our SME partners also expect to develop new lines of products and services through the HTP-GlycoMet programme, but also through future collaboration with HTP-GlycoMet partners beyond the lifetime of this project.;1818077,9;1818077,9;FP7-PEOPLE-2012-IAPP;/MC-IAPP;SVEUCILISTE U RIJECI;HR;"BIA SEPARATIONS DOO;GENOS DOO ZA VJESTACENJE I ANALIZU;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;SVEUCILISTE U RIJECI, MEDICINSKI FAKULTET";"SI;HR;DE";/LIF;1;0;0;1;0;0 110784;604182;FORMAMP;ONG;FP7-NMP;NMP.2013.1.2-2;FP7;Innovative Nanoformulation of Antimicrobial Peptides to Treat Bacterial Infectious Diseases;2013-12-01;2017-11-30;http://www.formampproject.com;Resistance to traditional antibiotics is a rapidly increasing problem that in a few years could make infections impossible to treat and bring the state of medical care back to the pre-antibiotic era from the beginning of the last century. Antimicrobial peptides (AMPs) have a huge potential as new therapeutics against infectious diseases as they are less prone to induce resistance due to their fast and non-specific mechanism of action. The aim of FORMAMP is to explore a number of innovative formulation and delivery strategies based on nanotechnology in order to improve the efficiency and stability of AMPs in clinical development. Functional delivery systems that can be applied directly on the infected site will be developed for treatment of infections in skin and burn wounds, as well as lung infections caused by Methicillin-resistant Staphylococcus aureus (MRSA), Pseudomonas aeruginosa and Mycobacterium tuberculosis (MTB). Formulation and delivery strategies to prevent and treat biofilm formation related to these conditions will be developed. Different nanoformulation platforms, particularly promising for peptide delivery, controlled release strategies and technologies against proteolytic degradation of peptides will be evaluated in the project. These include lipid-based systems such as lipidic nanocapsules, polymer-based structures such as dendrimers and microgels as well as nanostructured mesoporous silica. The possibility to formulate the nanostructured materials into efficient drug delivery systems such as a topical spray or gel and pulmonary aerosol will be evaluated. The effect of nanoformulated AMPs will be evaluated with state-of-the art in vitro models and in vivo models. The results of this interdisciplinary project will generate efficient treatment strategies combatting one of the largest threats to our health care system today, reducing healthcare costs and expand the growth of European enterprises within the field of pharmaceutics and nanomaterials.;10348954,9;7945494;FP7-NMP-2013-LARGE-7;/CP-IP;RISE RESEARCH INSTITUTES OF SWEDEN AB;SE;"INHALATION SCIENCES SWEDEN AB;KUNGLIGA TEKNISKA HOEGSKOLAN;Pergamum AB;UNIVERSITAET ULM;ADENIUM BIOTECH APS;UNIVERSITE D'ANGERS;ACADEMISCH ZIEKENHUIS GRONINGEN;UPPSALA UNIVERSITET;XSPRAY PHARMA AB (PUBL);Medical Products Agency;CENTRE HOSPITALIER UNIVERSITAIRE D'ANGERS;POLYMER FACTORY SWEDEN AB;LUNDS UNIVERSITET;SP PROCESS DEVELOPMENT AB;POLYPEPTIDE LABORATORIES (SWEDEN) AB";"SE;DE;DK;FR;NL";/SCI;1;0;0;1;0;0 90529;222628;POLYMODE;ONG;FP7-KBBE;KBBE-2007-3-2-07;FP7;Novel Polysaccharide Modifying Enzymes to Optimise the Potential of Hydrocolloids for Food and Medical Applications;2009-05-01;2013-04-30;http://www.polymode.eu/;The PolyModE project convenes an international, interdisciplinary, and intersectorial consortium to identify, characterise, and optimise novel polysaccharide modifying enzymes, and to develop robust fermentation strategies for their large-scale production, to exploit the potential of biopolymers for food, pharmaceutical, cosmetic, and technical applications. We have selected the six complex carbohydrates with the highest current market share or expected future market potential, namely alginate, carrageenan, chitosan, glycosaminoglycan, pectin, and xanthan gum. For each of these, the industrial partners have identified those enzymes which will answer to the most pressing needs or offer the most promising potential for improved production of polysaccharides with novel physico-chemical properties and biological functionalities. Primary targets will be alginate epimerases, carrageenan sulfatases, chitosan de-acetylases, glycosaminoglycan sulfatases, pectin de-acetylases, and xanthan gum de-acetylases. These enzymes together with secondary target enzymes, e.g. sequence specific lyases and hydrolases, will allow the generation and analysis of polymers and oligomers with novel, non-random patterns of modification. Two parallel approaches will be followed for each type of polysaccharide modifying enzyme, namely a knowledge-based genomic approach and a broad, un-biased metagenomic approach, e.g. using soil or sludge samples with a history of contact with the polysaccharide in question. A pipeline of three levels of fermentation systems will be established, ranging from lab-scale innovative expression systems with features shaped according to the specific characteristics of our target enzymes, through medium-scale, novel and unusual fermentation systems provided by a number of SME with highly specialised knowledge and expertise in developing and using such systems, to the established large-scale fermentation systems and facilities of market leaders in White Biotechnology.;8226733,87;5999948;FP7-KBBE-2007-2A;/CP-IP;WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER;DE;"LIBRAGEN;GENEART AG;LYON INGENIERIE PROJETS;GILLET CHITOSAN EURL;THE STEPHAN ANGELOFF INSTITUTE OF MICROBIOLOGY, BULGARIAN ACADEMY OF SCIENCES;SVERIGES LANTBRUKSUNIVERSITET;GTP TECHNOLOGY SA;WAGENINGEN UNIVERSITY;SANOFI-AVENTIS RECHERCHE & DEVELOPPEMENT;INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;DUPONT NUTRITION BIOSCIENCES APS;PETRA TEWES-SCHWARZER - CARE SENSE CONSULTING;ARTES BIOTECHNOLOGY GmbH";"FR;DE;BG;SE;NL;DK";/BIO;1;0;0;1;0;0 101702;283646;DASISH;ONG;FP7-INFRASTRUCTURES;INFRA-2011-2.3.1.;FP7;Data Service Infrastructure for the Social Sciences and Humanities;2012-01-01;2014-12-31;;"'DASISH provides solutions to a number of common issues relevant for the five ESFRI projects in social science and humanities, being CESSDA, CLARIN, DARIAH, ESS and SHARE and therefore is supporting infrastructure construction. These five infrastructures are presently at different stages in the process of establishing ERICs. DASISH has identified four major areas namely data quality, data archiving, data access and legal and ethics. The activities in these four major areas are based on a thorough analysis of the underlying architectures. The outcome forms the basis for educational activities and for outreach to the communities that are to benefit from the work. Through DASISH the participating infrastructures will not only obtain new solutions for specific problems and a consolidation of their infrastructure building, but will work out solutions facilitating interdisciplinary cross-walks of their researchers. This will be of mutual benefit for the five infrastructures and the communities they serve.'";8304039;5991052;FP7-INFRASTRUCTURES-2011-1;/CP-CSA-Infra;GOETEBORGS UNIVERSITET;SE;"UNIVERSIDAD POMPEU FABRA;TARTU ULIKOOL;GESIS-LEIBNIZ-INSTITUT FUR SOZIALWISSENSCHAFTEN EV;STICHTING CENTERDATA;KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW;TAMPEREEN YLIOPISTO;GEORG-AUGUST-UNIVERSITAT GOTTINGENSTIFTUNG OFFENTLICHEN RECHTS;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;NORSK SAMFUNNSVITENSKAPELIG DATATJENESTE AS;KOBENHAVNS UNIVERSITET;NATIONAL UNIVERSITY OF IRELAND MAYNOOTH;UNIVERSITA CA' FOSCARI VENEZIA;UNIVERSITY OF ESSEX;CITY UNIVERSITY OF LONDON;OESTERREICHISCHE AKADEMIE DER WISSENSCHAFTEN;UNIVERSITETET I BERGEN;KING'S COLLEGE LONDON";"ES;EE;DE;NL;FI;NO;DK;IE;IT;UK;AT";/SOC;1;0;0;1;0;0 94107;249390;EUROEVOL;ONG;FP7-IDEAS-ERC;ERC-AG-SH6;FP7;Cultural Evolution of Neolithic Europe;2010-05-01;2015-04-30;http://www.ucl.ac.uk/euroevol;The last 30 years have seen the rapid emergence and growth of a new high-profile interdisciplinary field, the study of cultural evolution, which has produced novel ways of understanding human cultural and socio-economic behaviour. In particular, it has produced mathematical models derived from evolutionary biology demonstrating the importance of culture and history in understanding human cultures and societies, while at the same time taking into account the adaptive dimension. The field has seen a great deal of theoretical development and some empirical work, not least by myself and colleagues at the UCL AHRC Centre for the Evolution of Cultural Diversity and its predecessor. However, there has been no substantive attempt to bring the different sub-fields of cultural evolutionary theory and method together in an integrated fashion and apply them to large-scale case-studies in history or prehistory to address specific questions concerning the links between demographic, economic, social and cultural patterns and processes. The aim of this proposal is to do that for the first time and in doing so to provide the basis for a new account of the role of farming in transforming early European farming societies, c.6000-2000 calBC, focussing on the western half of Europe, where the available data are best. The project will have a major impact on the field of cultural evolution by providing a model example for cultural evolutionary studies of early societies in other parts of the world. It will also provide important new insights into the history of European society and give a significant impetus to re-orienting the disciplinary field of archaeology, making it part of the broader inter-disciplinary endeavour of evolutionary social science, as other researchers follow its example.;2000000;2000000;ERC-2009-AdG;/ERC-AG;UNIVERSITY COLLEGE LONDON;UK;;;/SOC;1;0;0;1;0;0 105108;316682;INBIONET;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-ITN;FP7;Infection biology training network: shaping the future of infectious diseases treatments;2013-01-01;2016-12-31;;"'The increasing number of bacteria resistant to all antibiotics and antimicrobials and the virtual lack of antiviral drugs make necessary to develop therapeutics based on new targets/approaches. European-wide-acting sectors must permanently improve their capabilities and capacities to cope with these challenges. Thus, the demand for experts trained to understand infectious diseases in their whole complexity is rising. INBIONET is an initiative from seven academic groups internationally recognized in the fields of microbial pathogenesis, innate immunity and molecular recognition, an intensive research SME, Preclin Biosystems, a multinational pharmaceutical company, Sanofi-Aventis, and a technological park (ParcBit). INBIONET partners will embark on the analysis of bacteria, viruses and enteric parasites specified by various infection strategies to identify cellular pathways important for infection as well as pathogen determinants involved in disease progression. Therefore, trainees will receive a comprehensive overview of some key concepts that pathogens use to ensure their success. It is expected that this knowledge will lead to the development of innovative therapies based on the modulation of the host-pathogen interface. INBIONET training will also focus on key aspects dealing with know-how transfer between academia and industries, and entrepreneurship. The four-year INBIONET training programme, at the interface between microbiology, immunology and cellular biology, should help to train the next generation of European scientists in the competitive field of “microbial anti-immunology” and set the grounds for new preventatives and therapeutics. INBIONET academic and industrial partners do provide the necessary critical mass to offer a top level training not currently offered in such dimension by any European academic institution thereby giving trainees a thorough and truly interdisciplinary background to meet the demands of the European (scientific) labour market.'";3968982,54;3968982,54;FP7-PEOPLE-2012-ITN;/MC-ITN;THE QUEEN'S UNIVERSITY OF BELFAST;UK;"THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN;UNIVERSITAT WIEN;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;FUNDACIO D'INVESTIGACIO SANITARIA DE LES ILLES BALEARS RAMON LLULL;THE UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS;PRECLIN BIOSYSTEMS AG;ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE;INSTITUT PASTEUR;SANOFI-AVENTIS RECHERCHE & DEVELOPPEMENT";"IE;AT;DE;ES;UK;CH;FR";/LIF;1;0;0;1;0;0 109655;607602;SASSYPOL;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-ITN;FP7;Hierarchical Self Assembly of Polymeric Soft Systems;2013-09-01;2017-08-31;;'The production of the next generation of functional soft systems and materials capable of meeting the current and future demands of society in a sustainable manner will require both new technologies and highly trained scientists. Supramolecular chemistry provides a powerful approach to develop new self-assembled materials with emerging properties, such as healability, recyclability and facile processability. The SASSYPOL ITN will train the next generation of European scientists with the skills necessary to overcome such future demands and simultaneously develop new strategies for the preparation of hierarchically self-assembled polymeric soft systems, which greatly impact important fields such as biomedicine, energy, composite materials and sensing. The ITN unites many leading experts in the areas of supramolecular and polymer chemistry with partners from the industrial sector. Expertise of all partners encompasses the general areas of non-covalent chemistry, with individual research competencies focusing on a number of specific themes including liquid crystalline materials, hydrogen-bonded supramolecules, molecular systems based on host-guest interactions, and advanced modeling and characterisation techniques of complex polymeric and self-assembled materials. The complementarity and diversity realised in synthesis, analysis, and applications is crucial for successful research and training in this area. A number of partners from the private sector will extend the fellows’ training beyond that of traditional academic settings ?they will have the critical role of bridging fundamental science with application and commercialisation of the results. Indeed, SupraPolix (a SME), one of SASSYPOL’s industrial full partners is a perfect example of the commercialisation of cutting-edge science initially developed at an academic laboratory. Our activities will thus possess both breadth and quality that can only be achieved through an interdisciplinary pan-European effort.';3592910,2;3592910,2;FP7-PEOPLE-2013-ITN;/MC-ITN;THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;UK;"UNIVERSITA DEGLI STUDI DI PARMA;ELANTAS ITALIA SRL;THE UNIVERSITY OF MANCHESTER;ECOLE SUPERIEURE DE PHYSIQUE ET DECHIMIE INDUSTRIELLES DE LA VILLE DEPARIS;FORSCHUNGSZENTRUM JULICH GMBH;UNIVERSIDAD DE ZARAGOZA;SUPRAPOLIX BV;TECHNISCHE UNIVERSITEIT EINDHOVEN;UNIVERSITE DE FRIBOURG";"IT;UK;FR;DE;ES;NL;CH";/LIF;1;0;0;1;0;0 103365;301436;COGENT;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IOF;FP7;Control for Green Energy-Efficient Technologies;2012-12-01;2015-11-30;;The EU has set aggressive energy targets that will drive a significant increase in the use of renewable energy sources introducing large uncertainties in the power generation as well as the uptake of plug-in hybrid electric vehicles (PHEVs), offering a new source for balancing the power grid by providing large scale distributed storage capacity. The COGENT project will develop theoretical frameworks and practical tools for applying control and optimization to the energy management of PHEVs that are active participants in the Smart Grid in an interrelated way. Innovative control strategies are required that utilize variable loads and storages to ensure optimal performance and safety of the Smart Grid based on large amounts of data. The proposed project will address this problem by developing novel and sophisticated control and machine learning techniques, that are well suited for the increasingly complex, uncertain, high-speed and distributed characteristics of the Smart Grid. The success of this challenging and highly interdisciplinary program will be enabled by the collaboration with the host institutions, the Control, Intelligent Systems and Robotics group at UC Berkeley, a center of excellence in control and the Max-Planck-Institute for Intelligent Systems, a research group world famous for its work on machine learning. The fellow researcher provides an excellent background for the proposed project, which will be supported by the outstanding expertise of the host institutions, together providing the comprehensive knowledge required for the scientific and technological goals of the program. In addition to the development of high-quality and cutting edge research, the aim of this project is to promote the young outgoing researcher by boosting her skills, expertise and international network. The project will thereby equip the researcher with essential competences and prerequisites for an academic career in Europe and for contributing to European research excellence.;255453;255453;FP7-PEOPLE-2011-IOF;/MC-IOF;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;DE;;;/SCI;1;0;0;1;0;0 94896;256545;MTLE-HS;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-RG;FP7;Genomic sequence variants that correlate with gene expression and different epigenetic patterns modify risk for mTLE+HS;2010-04-01;2012-06-30;;"Epilepsy is the second most common neurological disorder after stroke and mesial temporal lobe epilepsy with hippocampal sclerosis (mTLE\HS) represents the most common epilepsy syndrome in adult patient with medically intractable partial epilepsy. Studies of genome-wide association (GWA) with epilepsy are critical to provide an unbiased assessment of genes contributing to disease risk and/or response to treatment. However the results of GWA studies give little information about the underlying disease mechanisms. The proposed research project will try to identify those genomic sequence variants that correlate with gene expression and different epigenetic patterns that could modify risk for mTLE\HS. Starting with an already established epilepsy GWA study, we propose to obtain gene expression and methylation data from 100 biopsy specimens obtained from well-characterized chronic pharmacoresistant mTLE\HS patients, who underwent resection of the temporal lobe at the National Hospital for Neurology and Neurosurgery (NHNN) and for whom we already have whole-genotyping data. Individuals will be matched for age, gender and ethnic background with healthy controls from two ongoing whole genome expression and methylation studies at UCL. The integration of gene expression with genetic variability will provide insights into the causal variants and how this may lead to mTLE\HS. In addition, we will investigate an additional biological mechanism, methylation that could alter an individual's susceptibility to mTLE\HS risk. Our interdisciplinary approach will contribute to the understanding of the molecular mechanisms underlying mTLE\HS pathology. In the long term, this understanding will lead to the preventative identification of high-risk patients and the development of novel therapies, aimed at the prevention of seizures and the cognitive impairment suffered by these patients.";56250;56250;FP7-PEOPLE-2009-RG;/MC-IRG;UNIVERSITY COLLEGE LONDON;UK;;;/SCI;1;0;0;1;0;0 98490;269271;TELASENS;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-IRSES;FP7;"Carbon Nanotubes Technologies in Pulsed Fibre Lasers for Telecom and Sensing Applications";2011-04-01;2015-03-31;;"Nanostructures such as carbon nanotubes (CNT), quantum dots, nanowires, are prime candidates as building blocks in nanotechnology, because they assemble themselves and have a combination of unique electronic, optical, thermal and mechanical properties. The optical properties of nanomaterials mainly depend on their size and shapes and can be optimized in a very broad spectral range. Importantly, such materials can display the resonant optical nonlinearities useful for generation of ultrashort pulse lasers, pulse shaping applications and noise suppression. Our goal is to create an ambitious research exchange program, with a strong interdisciplinary nature, crossing materials engineering, physics, chemistry and soft matter sciences to achieve a major breakthrough in the understanding of the optical properties of nanomaterials. This knowledge will be useful for development of efficient nonlinear optical (NLO) devices, using novel speciality fibres and waveguides. The final target of the program is implementation of a NLO device in fibre lasers in order to achieve ultrashort pulse generation in the optical range important for telecommunication, environmental and biological sensing. The exchange program will benefit from participation of leading experts in nanomaterials, optical spectroscopy, computation chemistry, fibre optics and lasers from both EU and Partner countries. Therefore it will be a very attractive and useful opportunity for training of early stage researchers.";201400;201400;FP7-PEOPLE-2010-IRSES;/MC-IRSES;ASTON UNIVERSITY;UK;"TTY-SAATIO;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV";"FI;DE";"/EMP;/SOC";1;0;0;1;0;0 102931;302684;PROLIFERA;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IEF;FP7;PROLIFERA - Proliferative Arrest and its Ecological Relevance as a Resource Allocation Strategy in Arabidopsis;2012-03-01;2014-04-29;;"'The study of heritable variation in ecologically relevant plant traits can lead to insights into evolutionary processes and to increased agricultural output. Resource allocation strategies in flowering plants are of great interest, from an ecological and agricultural point of view. As plants have a modular body plan, they often initiate reproductive organs sequentially and the maternal plant has to balance current and future expenditures on offspring to produce an optimal number of seeds. Control mechanisms exerted by reproductive structures over maternal growth have been observed in several plant species -amongst them important crops- and are termed “correlative controls”. Such mechanisms might represent offspring begging strategies in plants, whereby offspring influences maternal resource allocation patterns. The molecular bases and ecological relevance of these control mechanisms are, however, unclear. The applicant aims to i) use state-of-the art molecular techniques to investigate correlative controls in an annual plant ii) isolate genetic variation in the strength of controls that offspring exerts over maternal growth ii) apply recently developed methods in ecological competition experiments to compare fitness parameters amongst offspring from genetic variants and examine genotype-environment interactions. This will provide an ecological context to formulate an evolutionary hypothesis concerning the adaptive value of correlative controls in plants. The interdisciplinary project will be implemented at the University of Zurich under supervision of Prof. Schmid, a world-renowned ecologist located at the Institute of Evolutionary Biology and Environmental Sciences. It will be co-supervised by Prof. Grossniklaus (Institute of Plant Biology), expert in plant reproductive biology and genetics. The project will be a major step in the research career of the applicant Samuel Wuest, towards professional maturity and expertise at the intersection between disciplines.'";192622,2;192622,2;FP7-PEOPLE-2011-IEF;/MC-IEF;UNIVERSITAT ZURICH;CH;;;/SCI;1;0;0;1;0;0 92617;238551;MULTITERM;ONG;FP7-PEOPLE;FP7-PEOPLE-ITN-2008;FP7;Training Multidisciplinary scientists for Tissue Engineering and Regenerative Medicine;2009-10-01;2013-09-30;;MultiTERM is a training network providing multidisciplinary training for 13 early stage scientists in 5 host institutes that will deliver a number of excellently trained, highly employable scientists for companies and academia in the field of tissue engineering and regenerative medicine (TERM). The aging population of the EU requires the development of new treatment strategies for diseased, defective, or damaged tissues. Since donor material is often not available, artificial tissue needs to be developed for these purposes. Therefore, smart materials that can be used to replace and repair tissues should be developed. With better tissue engineering possibilities becoming available, improved methods to visualise the fate and effects of these implants are essential and need to be examined. TERM is a multidisciplinary field where scientists need to cut across traditional fields of study. They need to understand completely different aspects - ranging from material choice, cell biology, to clinical translation - to successfully design and clinically implement engineered tissue. Unfortunately, such scientists are scarce, because such TERM-specific interdisciplinary training is missing. To fill the gap that currently exists, the MultiTERM Network will provide early stage researchers with individual and centralized training in key elements of TERM: biomaterials, cell biology, bioreactors, animal modeling, clinical and industrial translation. The MultiTERM Partners, including the industrial partner, are recognized leaders in their fields - ensuring state-of-the-art training - with highly complementary, cross-sectorial skills, and have extensive prior FP experience, assuring achievement of this goal. During their training, the early stage scientists will develop new materials and implants for tissue engineering as well as state-of-the-art novel visualisation procedures to monitor the behaviour of the implanted tissues.;2879487;2879487;FP7-PEOPLE-ITN-2008;/MC-ITN;STICHTING KATHOLIEKE UNIVERSITEIT;NL;"EUROPEAN MEDICAL CONTRACT MANUFACTURING E.M.C.M. BV;UPPSALA UNIVERSITET;UNIVERSITAT ZURICH;UNIVERSITATSSPITAL BASEL";"NL;SE;CH";"/SCI;/EDU";1;0;0;1;0;0 92986;238804;SMALL;ONG;FP7-PEOPLE;FP7-PEOPLE-ITN-2008;FP7;Surfaces for molecular recognition at the atomic level;2010-01-01;2013-12-31;;The overarching aim of the SMALL ITN project is to train Early Stage Researchers in the field of ‘molecular recognition at surfaces’ from fundamental science to novel applications. For this task, SMALL combines European experts from surface science, nanotechnology, theory, chemical synthesis, physics, biology and industry, and thus takes a highly integrated approach to the training. The researchers will work within a well-structured scientific programme aimed at molecular recognition, underpinning the next generation of molecular sensors, catalysis, biomimetics, and molecular electronics. The programme of training will foster scientists who, in addition to being specialists in particular branches of molecular nanotechnology, have broad interdisciplinary experience in the experimental and theoretical techniques of molecular nanotechnology. Their hands-on training will be substantiated by a well-developed network training programme which will address both scientific and complementary skills. In their projects, the Early Stage Researcher will explore the nature of the interactions responsible for molecular and atomic recognition and the role that these play in the massively parallel self-assembly of supramolecular nanostructures, using a collaboration of cutting edge experimental and theoretical techniques. They will investigate how to achieve chemical selectivity at surfaces, including enantioselective recognition, by molecular and atomic surface modification as a route to novel catalysis and nanoscale sensors, drawing on expertise across different scientific disciplines and pioneering industrial partnerships.;4899085,18;4899085,18;FP7-PEOPLE-ITN-2008;/MC-ITN;THE UNIVERSITY OF NOTTINGHAM;UK;"AARHUS UNIVERSITET;THE UNIVERSITY OF READING;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;ECOLE NORMALE SUPERIEURE DE LYON;KARLSRUHER INSTITUT FUER TECHNOLOGIE;European Nano Invest AB;THE UNIVERSITY OF LIVERPOOL;LUNDS UNIVERSITET;UNIVERSIDAD AUTONOMA DE MADRID;UNIVERSITY COLLEGE LONDON";"DK;UK;DE;FR;SE;ES";"/SCI;/EDU";1;0;0;1;0;0 92470;243047;INCEL;ONG;FP7-IDEAS-ERC;ERC-SG-LS1;FP7;Revealing the molecular architecture of integrin mediated cell adhesion;2009-11-01;2015-10-31;;Cell adhesions play an important role in the organization, growth, maturation, and function of living cells. Interaction of cells with the extracellular matrix (ECM) plays an essential role in a variety of disease states , inflammation, and repair of damaged tissues. At the cellular level, many of the biological responses to external stimuli originate at adhesion loci, such as focal adhesions (FA), which link cells to the ECM . Cell adhesion is mediated by receptor proteins such as cadherins and integrins. The precise molecular composition, dynamics and signalling activity of these adhesion assemblies determine the specificity of adhesion-induced signals and their effects on the cell. However, characterization of the molecular architecture of FAs is highly challenging, and it thus remains unclear how these molecules function together, how they are recruited to the adhesion site, how they are turned over, and how they function in vivo. In this project, I aim to conduct an interdisciplinary study that will provide a quantum step forward in the understanding of the functional organization of FAs. We will analyze, for the first time, the three-dimensional structure of FAs in wild-type cells and in cells deficient in the specific proteins involved in the cell-adhesion machinery. We will study the effect of specific geometries on the functional architecture of focal adhesions in 3D. A combination of state-of-the-art technologies, such cryo-electron tomography of intact cells, gold cluster chemistry for in situ labeling, and modulation of the underlying matrix using micro- and nano-patterned adhesive surfaces, together with correlative light, atomic force and electron microscopy, will provide a hybrid approach for dissecting out the complex process of cell adhesion.In summary, this project addresses the properties of FAs across a wide range of complexities and dimensions, from macroscopic cellular phenomena to the physical nature of these molecular assemblies;1294000;1294000;ERC-2009-StG;/ERC-SG;UNIVERSITAT ZURICH;CH;BEN-GURION UNIVERSITY OF THE NEGEV;IL;"/BIO;/LIF";1;0;0;1;0;0 105902;309865;NEUROCODEC;ONG;FP7-IDEAS-ERC;ERC-SG-LS5;FP7;Neurobiological basis of collective decision making in the human brain;2013-01-01;2017-12-31;;We continually interact with each other & share information to make decisions together as friends, families, committees, juries, interest groups and institutions. The question of how collective decisions are made dates back many centuries and has been vigorously studied in social psychology and political economics, but the biological basis of collective decision making in human brain is almost entirely unknown. This question is arguably at the heart of human society’s urgent need to communicate effectively & find better ways of arriving at global collective decisions. My research has provided new and potentially important computational models of collective decision-making based on empirical data from visual psychophysics. I propose to characterize the neurobiological basis of joint decisions by combining recent advances in economics and social cognitive neuroscience in a novel interdisciplinary research program that will ask 4 questions: (1)How do we learn to make better collective decisions? (2)What are the brain mechanisms underlying the different psychological components of collective decision making? (3)What makes some people better & some others worse at joint decisions? (4)What is the role of the neuro-modulatory hormones oxytocin & testosterone in collective decisions? I plan to develop a formal theoretical model of collective decision-making (Q1) & use converging evidence from complementary methodologies e.g. behavioural experiments & fMRI (Q2), structural brain imaging (Q3) and neuro-pharmacology (Q4) to test & advance the model. My findings could help understand what physiological events underlie our ability to learn from experience to contribute effectively to group efforts and also disclose the biological basis that makes some of us better and some worse at working in groups . The results may provide a clearer picture of how hormonal interactions in the brain strike a balance between trusting ourselves vs accepting the opinion of others.;1486197;1486197;ERC-2012-StG_20111109;/ERC-SG;UNIVERSITY COLLEGE LONDON;UK;;;"/BIO;/LIF";1;0;0;1;0;0 92710;238316;NEURASYNC;ONG;FP7-PEOPLE;FP7-PEOPLE-ITN-2008;FP7;Academic-Industrial Training Network on Alpha-Synuclein-related Brain Diseases;2009-11-01;2013-10-31;;Parkinson’s Disease (PD) is the second most common neurodegenerative disorder. It is characterized pathologically by the accumulation of aggregated conformations of the presynaptic protein alpha-synuclein (ASYN) in cytoplasmic inclusions termed Lewy Bodies (LBs). Furthermore, aberrant aggregated species of ASYN accumulate in various disease states, such as Multiple System Atrophy, Diffuse LB Disease, LB Variant of Alzheimer’s Disease and others, collectively termed synucleinopathies. Point mutations and multiplications of the ASYN gene have been identified in PD, and there is also genetic evidence linking ASYN to sporadic PD. These data suggest that aberrant conformations of ASYN plays a central role in the pathogenesis of genetic and sporadic PD and likely of other devastating neurodegenerative conditions. The aim of this proposal is to create a network of European partners who will examine, using state of the art in vitro assays, and diverse cellular and animal models, including novel cellular and in vivo imaging modalities, ASYN conformations, regulation, and mechanisms of toxicity. Through this work, biomarkers and experimental therapeutics targeting ASYN will be tested. This network will create the opportunity for training of a number of early stage researchers in the diverse fields of protein chemistry, biochemistry, cell biology, neurobiology, and animal modeling of nervous system diseases, within an interdisciplinary setting, while exposing them to both Academic and Industrial environments.;2419227;2419227;FP7-PEOPLE-ITN-2008;/MC-ITN;EBERHARD KARLS UNIVERSITAET TUEBINGEN;DE;"AARHUS UNIVERSITET;Farfield Group Limited;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;BOEHRINGER INGELHEIM PHARMA GMBH &CO KG;IDRYMA IATROVIOLOGIKON EREUNON AKADEMIAS ATHINON;BIOALVO S.A.;LANCASTER UNIVERSITY;INSTITUTO DE MEDICINA MOLECULAR JOAO LOBO ANTUNES;LUNDS UNIVERSITET";"DK;UK;DE;EL;PT;SE";"/SCI;/EDU";1;0;0;1;0;0 108779;326408;XCULTDEVRESALL;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IEF;FP7;The cross-cultural development of resource allocation behaviour;2013-10-01;2015-09-30;;In human society, there is a need to regulate the allocation and distribution of goods to prevent conflicts over access to resources. The developmental trajectory of how children learn resource allocation rules has been established for children in Western cultures, but very little is known about the cross-cultural development of these behaviors. My project will thus investigate the cross-cultural development of resource allocation behavior (1) by designing a comprehensive battery of behavioral tests for 3- to 8-year-old children and (2) by using this test battery to study children in two different small-scale cultures in Kenya and Namibia, respectively, and in Germany. This project will be supervised by Prof Michael Tomasello at the Department of Comparative and Developmental Psychology (MPI for Evolutionary Anthropology, Germany), who is a world-leading authority on the development of social cognition and cultural learning and has successfully mentored more than 50 early career researchers. The Department offers a vibrant, highly prolific, interdisciplinary environment with about 40 researchers at different stages of their careers and unique research facilities in the ERA for conducting developmental, cross-cultural research (e.g., a developmental lab, field-sites in Kenya & Namibia, support staff). By conducting this project I will gain crucial postdoctoral experience and (1) acquire new scientific skills in cross-cultural methodology, anthropological knowledge and field-work experience in Africa, (2) gain new transferable skills e.g. regarding research management and the dissemination of research findings (scientific & general public), and (3) establish a network of collaborations with renowned experts – all of which will prepare me for a career as an independent researcher at a European institution. This timely project will be highly relevant for different disciplines in the behavioral sciences and has the potential to make a significant impact on the field.;161968,8;161968,8;FP7-PEOPLE-2012-IEF;/MC-IEF;MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV;DE;;;/SCI;1;0;0;1;0;0 105410;316832;OLIMPIA;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-ITN;FP7;TRAINING NETWORK ON ORGANIC OPTOELECTRONICS INTEGRATED WITH LIVING SYSTEMS FOR NEUROSCIENCE INVESTIGATIONS AND APPLICATIONS;2012-10-01;2016-09-30;;'OLIMPIA is a training network initiative built on research and development of innovative organic optoelectronic devices interfaced and integrated with living systems. The living systems of choice are neural cells (glia and neuron) that will be interfaced and integrated in vitro and in vivo with different organic electronic and optoelectronic devices (such as OLED, OFET/OLET, OECT, OPD). The major objective of OLIMPIA is to establish an innovative training program aimed at enabling and supporting the development of a novel supradisciplinary field that combines the worlds of organic optoelectronics and of neuroscience. Novel tools based on organic optoelectronic devices will be engineered and developed to stimulate and to record neuron bioelectrical activity, such as neuron excitability and membrane polarization, as well as to modulate cell proliferation and neurite outgrowth. The OLIMPIA research will provide radically new understanding of neural cell-cell communication processes and will impact a wide variety of fields, from biomedical research to neuro-regenerative medicine. The OLIMPIA consortium is both interdisciplinary and intersectorial. It includes key European players with long standing and internationally recognized research tradition in the field of organic electronics and optoelectronics, organic synthesis as well as neural cell biology and neurophysiology and, as such, is uniquely qualified to implement this ambitious supradisciplinary training program. Moreover, the consortium combines 10 partners belonging to 6 European countries from academia, public research centers and industrial labs thereby offering an exciting and broad training landscape to the new generation of researchers.';4011185,41;4011185,41;FP7-PEOPLE-2012-ITN;/MC-ITN;CONSIGLIO NAZIONALE DELLE RICERCHE;IT;"IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE;TECHNISCHE UNIVERSITAET MUENCHEN;FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA;HISTOCELL SL;UNIVERSITETET I OSLO;E.T.C. SRL;ECOLE NATIONALE SUPERIEURE DES MINES DE SAINT-ETIENNE;UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA";"UK;DE;IT;ES;NO;FR";/LIF;1;0;0;1;0;0 100451;273737;Grasp Control & BMI;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-IEF;FP7;Grasp-Related Neuronal Activity in Monkey and Human and Its Applicability in BMI;2012-06-01;2014-05-31;;"The complexity and precision of human hand control is staggering and unravelled, yet, its neuronal control is not well understood. Loss of this ability has devastating consequences for a human’s daily life. Restoring this ability and, thus, bringing relief to the patient’s condition should be an important aim of science. We propose an interdisciplinary investigation of both the neuronal activity controlling skilled hand movements and how this activity can be used in a Brain-Machine Interface (BMI) to control hand postures suitable for grasp of different everyday objects. For example, relevant patients rank the loss of skilled grasp as one of the most debilitating features of their injury (Anderson, 2004). Thus, grasp BMIs are of great importance, but not yet available. We will investigate grasp-related neuronal activity in monkeys and human volunteers based on recordings of (i) intracortical single-unit activity (SUA) and local field potentials (LFP) through multiple electrodes in monkey primary motor cortex (M1), ventral pre-motor cortex (PMv) and boundary areas between M1 and PMv, and (ii) non-invasive human magnetoencephalograms (MEG). Recent studies have shown grasp-specific neuronal activity in SUA and LFP recorded in monkey. We will record grasp-related activity simultaneously at various sites ranging from PMv to M1. Central points are the investigation of the spatial distribution of this activity across motor areas and different cortical laminae, the long-term stability and how this activity is modulated by novel motor tasks. We will also assess how these points affect the decoding of different grasps in a potential BMI and whether human MEG shows similar grasp specificity during execution and imagination of grasp, which is significant for patients controlling a BMI by imagining performance of different actions. The ultimate goal is precise, dexterous, real-time BMI grasp control of hand prostheses; our project represents a first step in this direction.";209092,8;209092,8;FP7-PEOPLE-2010-IEF;/MC-IEF;UNIVERSITY COLLEGE LONDON;UK;;;"/EMP;/EDU;/NET";1;0;0;1;0;0 92537;242008;LIFEVALVE;ONG;FP7-HEALTH;HEALTH-2009-1.4-2;FP7;Living autologous heart valves for minimally invasive implantable procedures;2009-11-01;2015-04-30;;Cardiovascular disease still represents the Killer No.1 in the EU accounting for substantial morbidity/mortality and health care cost. Heart valve replacement represents the most common surgical therapy for valvular heart disease with almost 200.000 annual implantations worldwide. Currently, heart valve prosthesis-associated problems occur in 30-35% of patients within 10 years, frequently necessitating risky re-operations. A particularly severe problem relates to children with congenital heart defects (1% of all newborns) who cannot be treated efficiently due to the lack of growths of the clinically available “artificial” valve prostheses. The principal objective of the LifeValve project is to develop a new therapeutic strategy to treat heart valve disease patients more efficiently. Two novel life science technologies will be combined: tissue engineering and minimally invasive implantation technology. In particular, the scientific and technological approach of the LifeValve project is to develop a clinically relevant tissue engineered living heart valve, with the capacity of regeneration and growths which can be implanted by minimally invasive catheter technology. First clinical trials will be enrolled in paediatric patients addressing the currently unmet dramatic medical need for growing implants. A highly interdisciplinary approach combines basic sciences, medical research, engineering and clinical practice. In addition, close industry-academia collaborations are integrated. It is expected that new knowledge applicable for a much broader field of cardiovascular diseases will be generated by the unique combination of consortium partners each representing opinion leaders in their fields. The consortium is compact comprising all the necessary expertise and skills to realize the precisely planned work in a short period of time.The close collaboration of the well interconnected LifeValve consortium will most efficiently contribute to an added value for the EU.;16062828,6;9876352;FP7-HEALTH-2009-single-stage;/CP-IP;UNIVERSITAT ZURICH;CH;"MEDIZINISCHE UNIVERSITAET WIEN;pfm Produkte fur die Medizin AG;DEBRECENI EGYETEM;DEUTSCHES HERZZENTRUM BERLIN;XELTIS AG;TECHNISCHE UNIVERSITEIT EINDHOVEN;XELTIS BV";"AT;DE;HU;CH;NL";"/MED;/MBI";1;0;0;1;0;0 107238;311637;MORPHOCORDIV;ONG;FP7-IDEAS-ERC;ERC-SG-LS3;FP7;The inherent morphological potential of the actin cortex and the mechanics of shape control during cell division;2013-03-01;2018-02-28;;The shape of animal cells is primarily determined by the cellular cortex, a cross-linked network of actin and myosin lying directly beneath the plasma membrane. Although it is increasingly clear that the study of cell mechanics is essential to understand cellular morphogenesis, the physical properties of the cortex are poorly understood. Our previous study on the mechanics of cytokinesis identified cortex tension, network turnover and cellular elasticity as key mechanical parameters controlling cell morphology. A physical description coupling cortex mechanics to cellular shape changes indicates that modulation of these three key parameters could be sufficient to induce a variety of morphological behaviors, including symmetric ingression of a contractile ring, cortex oscillations, and even asymmetric cell cleavage. The aim of this proposal is to reveal the intrinsic shape-generating potential of the cortex and to understand how this potential is used and controlled during cell division. To do so, we will first investigate how cortex tension, turnover and cell elasticity are controlled throughout division. We will test our understanding of cell shape mechanics by exploring how perturbing these properties affects the shape of the dividing cell. We will then explore whether cortical contractions can lead to asymmetric cytokinesis by attempting to induce differences in size between daughter cells by mechanical perturbations. Finally, we will use blebs separated from cells as model isolated cortices and investigate the control of shape dynamics in this simplified system. Our interdisciplinary approach will produce an integrated description of the mechanical function of the cortex in cell shape changes. More generally, I expect that this work will unveil some of the fundamental principles of cell morphogenesis by resolving how the coordinated regulation of a single set of physical parameters can unify seemingly disparate cellular morphogenetic events.;1500000;1500000;ERC-2012-StG_20111109;/ERC-SG;UNIVERSITY COLLEGE LONDON;UK;;;"/BIO;/LIF";1;0;0;1;0;0 85481;216837;ATRACO;CLO;FP7-ICT;ICT-2007.8.2;FP7;Adaptive and Trusted Ambient Ecologies;2008-01-01;2011-06-30;;ATRACO considers ambient ecologies consisting of people, context-aware artefacts and digital commodities (e.g., services and content). Members of the ecology are able to adapt to each other and form trusted ad hoc collaborations to achieve specific goals resulting from the need to serve specific human activities. The aim of this proposal is to research the factors and develop the technologies that will lead to the realisation of such ecologies (ATRACOs), following an interdisciplinary effort which involves Computer Science, HCI, AI, Control Theory and Sociology. Key factors of the ATRACO problem space that will be examined include adaptation, interoperability, context awareness, user interaction and dynamicity of trust. We will focus our efforts on seeking abstractions and mechanisms to mark the digital boundaries of ATRACOs for establishing trust relationships between its members, based on the concepts of digital territory and bubble, and to devise adaptation mechanisms based on supervisory control theory of discrete event systems and type-2 fuzzy logic. The project objectives are:
.To understand the structure, principles and dynamics of the ATRACO problem space and to develop a conceptual framework consisting of a set of concepts implemented as an ontology, a novel interaction metaphor, implemented as a language and a layered architecture implemented with a set of components.
. To research and implement the adaptation mechanisms and privacy policies, as part of the component platform. Adaptation will be provided in terms of artefact operation, ecology composition, network selection and man-machine interaction with respect to user context and behaviour.
. To validate the results of our research by developing an integrated application testbed. We will experiment with our proposed component platform both within a testbed (iDorm-2 of UEssex) as well as within a simulation environment.;2552080;1949992;FP7-ICT-2007-1;/CP;UNIVERSITAET ULM;DE;"UNIVERSITE PARIS 8 VINCENNES SAINT-DENIS;UNIVERSITE PARIS-SUD;UNIVERSITY OF ESSEX;INACCESS NETWORKS;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;INSTITOUTO TECHNOLOGIAS YPOLOGISTONKAI EKDOSEON DIOFANTOS";"FR;UK;EL";"/ELM;/IPS;/TEL";1;0;0;1;0;0 98571;274896;Action and Time;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-IIF;FP7;Perception of Time during Action Preparation;2012-03-08;2014-03-19;;"Expert baseball players commonly report that they feel the ball ‘slowing down’ when about to swing their bat. Their comments raise an interesting question of how humans perceive time prior to action, in other words, how motor preparatory activity effects on visual processing to change the subjective flow of time. Every daily event is associated with time, and we intuitively feel that we live on a constant and continuous time line. However, studies have revealed that physical temporal events and the perception of these events are not always matched. This counterintuitive nature of temporal perception has fascinated philosophers and scientists for centuries. Since humans are moving animals, perception of time must also be studied in an active situation. However, most studies relating temporal perception have, thus far, focused on static sensory processing and few studies have addressed how action can modulate an actor’s perception of time. The aim of this proposal is to understand the modulation of human temporal perception in an active context; focusing on the period when the brain is preparing for action. A series of behavioural and electrophysiological studies will be conducted to reveal the neuronal mechanism involved in this process. State-of-art machine learning algorithms will be used to analyze brain activity, and also a recently developed brain stimulation technique will be used to modulate brain activity, in order to elucidate the causal relationship between brain activity and temporal perception. The proposed research is expected to advance research in neurocognition of action, a distinctively European research field, by incorporating state-of-art research techniques. It will also facilitate interdisciplinary interaction between related fields (neuroscience, psychology, engineering and philosophy) within the European research community, and will contribute to building and maintaining connections between European and Japanese research communities.";210092,8;210092,8;FP7-PEOPLE-2010-IIF;/MC-IIF;UNIVERSITY COLLEGE LONDON;UK;;;"/SOC;/COO";1;0;0;1;0;0 107024;332622;EISRI II;ONG;FP7-SIS;SiS;FP7;"""European Intersectoral Summit on Research and Innovation -second edition- """"The Role of the Media in Responsible Research and Innovation""""""";2012-10-01;2013-07-31;;"Under the auspices of the Irish Presidency of the Council of the EU, the Permanent Platform of AC will hold the second edition of the European Intersectoral Summit on Research and Innovation in February 2013. The Summit will be organised with the participation of the Irish Ministry for Jobs, Enterprise and Innovation and the actors engaged in AC in Ireland (Trinity College Dublin, Irish Times). The EISRI 2013 edition will focus on the influence of communication and media on Responsible Research and Innovation (RRI) and is designed to create a unique opportunity for intersectoral and interdisciplinary discussions between leading stakeholders to: a. Continue the conversation initiated during the “Science in Dialogue” Conference held during the Danish presidency to develop a European model for Responsible Research and Innovation; b. Explore the role of media in the European model for Responsible Research and Innovation; c. Facilitate the formation of professional networks, knowledge sharing, and exchange of best practices. d. Come up with concrete recommendations on what has to be done in the short terms at a European level to reach the long term objectives; The conference will bring together leaders and key representatives of research institutions, businesses, media, NGOs, CSOs, policy makers and professional science communicators to discuss and reflect on the relationship between science and society. EISRI II will present high-level speakers including former heads of state and key representatives of the European institutions and national governments as well as leaders from leading research institutions, businesses and media. The dedicated workshops will be designed to reflect the key issues in this area and to promote “out of the box” thinking and participatory processes. The conference will take place at Trinity College Dublin, Ireland, from February 25 to February 26 2013.";594605;400000;FP7-Adhoc-2007-13;/CSA-SA;ATOMIUM CULTURE;BE;;;"/SCI;/SOC";1;0;0;1;0;0 98633;273295;SelfBioLogics;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-IOF;FP7;Mimicry of biology supramolecular logics towards self-assembly of artificial components for life;2011-04-01;2014-03-31;;"Whether a cell adheres to the extracellular matrix, or biological signals propagate within and between cells, highly selective interactions occur between the molecular ‘partners’ that materialize the process. Supramolecular chemistry studies the basic features of these interactions (knowledge) and their implementation for the design of non-natural systems (technology). This field bridges molecular chemistry and physics with biology, providing a interdisciplinary platform to understand biological structure (self-assembly) and function (recognition, reactivity and transport). Peptides that self-assemble in ordered nanostructures are a particular case of supramolecular chemistry. Peptides possess the biocompatibility and chemical diversity found in proteins, being particularly interesting for regenerative medicine and nanomedicine. Until now, peptide self-assembly systems have been studied individually. However, biological structures form in highly dense and heterogeneous molecular environments, such as the cytosol and extracellular matrix. The main scientific objective of this project is to recreate part of this complexity, by creating multi-component peptide self-assembly systems that form independent nano-assemblies in the same physical space. These systems will be used to provide technological solutions for the regeneration of ischemic neuronal tissues (artificial extracellular matrix) and the refined release of growth factors (capsules). These systems are also designed to be intermediate steps towards much more challenging future career objectives, namely cell-like bioreactors with the ability of protein production, self-maintenance or, even, self-replication. The beauty of this endeavor is that in the way towards such challenging scientific objectives, quite promising technological solutions can be derived, benefiting mankind health and welfare in ways that at the moment can just be painted with the faint colors of our imagination.";246360,8;246360,8;FP7-PEOPLE-2010-IOF;/MC-IOF;TECHNISCHE UNIVERSITEIT EINDHOVEN;NL;;;"/EMP;/SOC;/COO";1;0;0;1;0;0 95818;251304;REAL-SMART;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IAPP;FP7;Using real-time measurements for monitoring and management of power transmission dynamics for the Smart Grid;2010-09-01;2014-08-31;http://www.imperial.ac.uk/process-automation/research/wams/real-smart/;"Power transmission in Europe is entering a period of significant renewal and technological change because the electrical transmission grids face increases in new and variable energy sources, especially from large scale wind power generators. They therefore face future challenges of operation and control. Changes happening in the process industries will also have an impact on electrical supply because electric motors are taking over from traditional gas turbine drivers for large-scale process equipment such as compressors. On the other hand, new measurement and data acquisition methods such as phasor measurement units are allowing greatly improved observation of the transmission grid. In the light of these changes, there is a need for a new action to give Europe a significant lead in methods for enhanced power transmission system operation using emerging measurement technologies. The REAL-SMART proposal presents a balanced programme of applied R-and-D to address measurement-based monitoring and management of the high voltage transmission grid. It involves electrical transmission system operators, companies that supply technologies and components, and universities. The REAL-SMART consortium is interdisciplinary with experts in electrical power systems, modelling, instrumentation, signal analysis, equipment condition monitoring, and automation of oil & gas processes. The consortium will conduct research and undertake secondments to transfer experience and knowledge both ways between Academia and Industry. The project integrates in-depth understanding of the power system operational issues with analysis of state-of-the-art measurements and first-principles physical knowledge. It will invent and develop state-of-the-art tools that will be deployed by the transmission system operators, and will produce trained and experienced personnel. We aim to take a pivotal role in the creation of technology for intelligent operation of the wide-area transmission grids of the future";1085754;1085754;FP7-PEOPLE-2009-IAPP;/MC-IAPP;IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE;UK;"STATNETT SF;ABB SCHWEIZ AG;TECHNISCHE UNIVERSITAET GRAZ;FINGRID OYJ;AALTO KORKEAKOULUSAATIO SR;NATIONAL GRID ELECTRICITY TRANSMISSION PLC;ABB AS;ABB SPZOO;GENERAL ELECTRIC DEUTSCHLAND HOLDING GMBH";"NO;CH;AT;FI;UK;PL;DE";"/SCI;/EDU;/ITT";1;0;0;1;0;0 102988;290852;AIRSEA;ONG;FP7-IDEAS-ERC;ERC-AG-PE10;FP7;Air-Sea Exchanges driven by Light;2012-04-01;2017-03-31;;"The scientific motivation of this project is the significant presence of organic compounds at the surface of the ocean. They form the link between ocean biogeochemistry through the physico-chemical processes near the water-air interface with primary and secondary aerosol formation and evolution in the air aloft and finally to the climate impact of marine boundary layer aerosols. However, their photochemistry and photosensitizer properties have only been suggested and discussed but never fully addressed because they were beyond reach. This project suggests going significantly beyond this matter of fact by a combination of innovative tools and the development of new ideas. This project is therefore devoted to new laboratory investigations of processes occurring at the air sea interface to predict emission, formation and evolution of halogenated radicals and aerosols from this vast interface between oceans and atmosphere. It progresses from fundamental laboratory measurements, marine science, surface chemistry, photochemistry … and is therefore interdisciplinary in nature. It will lead to the development of innovative techniques for characterising chemical processing at the air sea interface (e.g., a multiphase atmospheric simulation chamber, a time-resolved fluorescence technique for characterising chemical processing at the air-sea interface). It will allow the assessment of new emerging ideas such as a quantitative description of the importance of photosensitized reactions in the visible at the air/sea interface as a major source of halogenated radicals and aerosols in the marine environment. This new understanding will impact on our ability to describe atmospheric chemistry in the marine environment which has strong impact on the urban air quality of coastal regions (which by the way represent highly populated regions ) but also on climate change by providing new input for global climate models.";2366276;2366276;ERC-2011-ADG_20110209;/ERC-AG;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FR;;;"/PSE;/ENV;/EAR";1;0;0;1;0;0 96174;247260;DPHOTOD;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IRSES;FP7;Dendrimers for photonic devices;2010-10-01;2013-09-30;;The goal of this interdisciplinary research project is to develop synthetic methods toward new types of dendrimers with tetrapyrrolic core and (indolo)carbazole dendrons, to reveal and analyse physical and chemical mechanisms of control of the luminescence response of dendrimers, and to create a basis for their resulting applications as molecular photonic devices. Combined efforts of synthetic chemists, spectroscopists and theoreticians from Western and Eastern Europe will be applied to achieve this aim. New types of dendrimers with tetrapyrrolic core possessing promising luminescent features, will be synthesized. Physical and chemical mechanisms of manipulation of their optical response will be revealed and analysed with using diverse spectroscopic approaches including steady-state and transient absorption, luminescence, fluorescence line narrowing, infra-red and Raman spectroscopies, luminescence microscopy and single molecule detection at ambient and low temperatures. The two-photon absorption spectroscopy will be applied for the design of infra-red light harvesting antennae and nonlinear optical devices. Theoretical methods will be applied to obtain the optimized molecular conformation of the dendrimers and to establish the pathways of the migration of excitation energy. The realization of this project will lead to the deeper understanding of fundamental processes of light energy transformation in supramolecular systems, which provides the basis for the design of efficient luminescent sensors and photonic devices that will be available for broad implementation.;228600;228600;FP7-PEOPLE-2009-IRSES;/MC-IRSES;LUNDS UNIVERSITET;SE;"TECHNISCHE UNIVERSITAET ILMENAU;KATHOLIEKE UNIVERSITEIT LEUVEN";"DE;BE";"/SCI;/EDU;/ITT";1;0;0;1;0;0 108041;323727;Fragsus;ONG;FP7-IDEAS-ERC;ERC-AG-SH6;FP7;Fragility and sustainability in restricted island environments: adaptation, cultural change and collapse in prehistory;2013-05-01;2018-04-30;;"Sustainability of societies in a restricted or fragile environment forms a perpetual question, past and present underpinning questions of the rise and fall of civilisation. Today, the eroded Maltese islands support one of the densest human populations in the world. When first colonised in the 6th millennium BC, pristine soil and forest covered the landscape, but within centuries the landscape was bare and under intensive cultivation. The Neolithic perpetrators of the original clearance developed a sophisticated if isolated island civilisation in the face of the precarious environment and limited natural resources. Their megalithic temples focused on ritual feasting whilst complex social organisation controlled food distribution. Over centuries, Malta maintained an intensive subsistence economy and a controlled population, but 2500 years after the first settlement that socio-economic system seems to have imploded resulting in the collapse of its island civilisation. What precise conditions led to this collapse, and was there complete or only partial economic and cultural failure? Did external factors - episodes of climatic instability, sea-level change, disease, invasion – impact irreversibly on the island inhabitants, or did over-intensification cause internal political and economic failure? Were the islands abandoned or was life sustained on them? Were other small islands affected in similar ways? These questions underpin my investigation which aims to extract eroding and fragile environmental and archaeological evidence from rapidly deteriorating landscapes. The goal is to understand the relationship between environmental change, stress and cultural continuity or collapse. I will address these questions through application of modern interdisciplinary environmental sciences (including palynology, climate studies, dating, dietary isotopes and landscape archaeology) to establish the impact of environmental change on island populations.";2491768;2491768;ERC-2012-ADG_20120411;/ERC-AG;THE QUEEN'S UNIVERSITY OF BELFAST;UK;"THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;UNIVERSITY OF PLYMOUTH;HERITAGE MALTA;SUPERINTENDENCE OF CULTURAL HERITAGE-SOVRINTENDENZA TAL PATRIMONJU KULTURALI SCH;UNIVERSITA TA MALTA";"UK;MT";/SOC;1;0;0;1;0;0 191238;618104;HERITAGE PLUS;ONG;FP7-ENVIRONMENT;ENV.2013.6.5-6;FP7;ERA-NET Plus on Cultural Heritage and Global Change Research;2013-10-01;2018-09-30;;"The main objective of the HERITAGE PLUS proposal is to pool the necessary financial resources from the participating national programmes and the European Community and to launch a single Joint Call for Proposals for research projects in the cultural heritage field that will be evaluated and managed jointly by the participating programmes. The 18 Partners have a strong background in designing, promoting and managing transnational, collaborative research programmes having participated to the Era Net Projects NET HERITAGE, HERA and DCNET and implemented the Joint Programming Initiative “Cultural Heritage and Global Change: a new challenge for Europe” (JPICH). Within JPICH, the launch of the first pilot call, actually open, represents the factual commitment of Partners to implement transnational research programming. The HERITAGE PLUS project is fully in line with the JPICH as part of the implementation of the Strategic Research Agenda (SRA) and of the Action Programme. Consequently the HERITAGE PLUS call will be focused in topics on tangible cultural heritage research, developing new methodologies, technologies and products for the assessment, protection and management of historical and modern artefacts, buildings and sites, while not excluding interlinked aspects of digital and intangible heritage, following the interdisciplinary basic criteria on which the JPICH SRA devolved. This collaborative approach will provide a better use of public resources, while the European Community contribution to the Joint Call budget will stress the high interest generated by this common action. This ERA NET PLUS action will support the JPICH by proposing concrete solutions for pooling national expertise and resources and establishing closer and robust collaboration among the participating States in the field of cultural heritage. The HERITAGE PLUS action will improve the coordination of national research activities and policies in the domain of cultural heritage research.";9286119;3064419;FP7-ERANET-2013-RTD;/CSA-ERA-Plus;MINISTERO PER I BENI E LE ATTIVITA CULTURALI;IT;"NEDERLANDSE ORGANISATIE VOOR WETENSCHAPPELIJK ONDERZOEK;MINISTERE DE LA CULTURE ET DE LA COMMUNICATION;STYRELSEN FOR FORSKNING OG UDDANNELSE;Ministry of Environmental Protection;IDRYMA PROOTHISIS EREVNAS;Lietuvos mokslo taryba;MINISTERO DELL'ISTRUZIONE, DELL'UNIVERSITA' E DELLA RICERCA;MINISTERIE VAN ONDERWIJS, CULTUUR EN WETENSCHAP;RIKSANTIKVARIEAMBETET;MINISTERIO DE ECONOMIA, INDUSTRIA Y COMPETITIVIDAD;Ministerul Educatiei Nationale;THE ARTS AND HUMANITIES RESEARCH COUNCIL;NORGES FORSKNINGSRAD;MINISTERSTWO KULTURY I DZIEDZICTWA NARODOWEGO;SERVICE PUBLIC FEDERAL DE PROGRAMMATION POLITIQUE SCIENTIFIQUE;AGENCE NATIONALE DE LA RECHERCHE;FUNDACAO PARA A CIENCIA E A TECNOLOGIA";"NL;FR;DK;IL;CY;LT;IT;SE;ES;RO;UK;NO;PL;BE;PT";/ENV;1;0;0;1;0;0 110579;607886;CLaSSiC;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-ITN;FP7;deviCes for Light impact on Skin Stem Cells;2013-10-01;2017-09-30;;CLaSSiC is an interdisciplinary, intersectoral research project, leveraging insights on molecular, cellular and biophysics impact of light on skin stem cells towards novel devices for regenerative therapy. The aging demographic means a growing need for effective therapeutic solutions addressing age-related and age-independent skin disorders, including failure of wound healing, hair loss or unwanted hair growth. All have negative psychological impact affecting millions and present significant personal and clinical cost burdens to society. Light therapy is known but has developed rather empirically, lacking basic research. CLaSSiC will unlock the potential for new light-based devices for management of skin and hair disorders. State-of-the art scientific solutions can only be found when complimentary partners work synergistically. CLaSSiC is a two-partner network comprising PHILIPS (Netherlands) and the Centre for Skin Sciences (University of Bradford UK). A board of 8 very experienced supervisors will team-up across disciplines and sectors to train and mentor 3 early stage researchers who will work at superb research facilities at both locations. The objectives of CLaSSiC combine scientific training in skin biology, biophysics of light interaction with skin stem cells, and device design. Students’ projects will deliver the science required for PHILIPS to develop devices to treat specific skin and hair disorders such as healing wounds and modulating hair growth. Students have an innovative training plan and will benefit from the entrepreneurial environs of the High Tech Campus and an ethos of excellence in basic and applied research at the University of Bradford. CLaSSiC will train the next generation of leaders in ‘physics and physiology’ towards opportunities in regenerative therapies. Future leaders from this project will possess both the competitive skills and experience required to establish a leading position for the EU in light-stem cell interactions.;795030,88;795030,88;FP7-PEOPLE-2013-ITN;/MC-ITN;UNIVERSITY OF BRADFORD;UK;PHILIPS ELECTRONICS NEDERLAND B.V.;NL;/LIF;1;0;0;1;0;0 109277;607114;RRD4E2;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-ITN;FP7;Rational Reactor Design for Enhanced Efficiency in the European Speciality Chemicals Industry;2013-10-01;2017-09-30;;"'This project aims at a significant increase in the ecological and economic efficiency of today’s chemical processes by means of rational reactor design. Increasing economic pressure of European speciality chemicals producers from competitors of emerging economies requires the implementation of the latest progress in model-based reactor design and optimization into industrial practice. For this, the proposed project entangles a leading European speciality chemicals producer, LONZA, Switzerland, with a prime research site in Chemical Reaction Engineering and Reactor Design, FAU Erlangen, Germany. Current industrial production processes for speciality chemicals are commonly improved incrementally in an iterative trial-and-error approach. In order to pave the way for real breakthroughs in chemical reactor technology, a novel model-based design approach is required, which enables the design of innovative tailor-made reactors. As examples of high industrial relevance, three processes from LONZA are chosen for a thorough evaluation and optimization. Based on fundamental thermodynamic and kinetic data, the ESRs will apply a rigorous optimization strategy to define the optimal reaction conditions and to derive the best suited reactor design for each of the selected processes. Innovative additive manufacturing techniques such as Selective Electron Beam Melting enable the manufacturing of the reactor components, even with complex geometries. The identified reactor concepts are then experimentally evaluated and optimized at the laboratory scale in order to demonstrate the optimization potential for the application on the industrial level. With the optimized processes and the methods and tools at hand the European speciality chemicals industry is strengthened and excellently prepared for future competition. Moreover, the ESRs are trained in a highly interdisciplinary environment which will qualify them in a unique way for the needs of the European speciality chemical industry.'";668456,97;668456,97;FP7-PEOPLE-2013-ITN;/MC-ITN;LONZA AG;CH;FRIEDRICH-ALEXANDER-UNIVERSITAET ERLANGEN NUERNBERG;DE;/LIF;1;0;0;1;0;0 109498;607417;CATSENSE;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-ITN;FP7;Design of novel high performance catalysts and biosensors based on deposited mass-selected clusters assisted by computational theoretical screening;2014-01-01;2017-12-31;;"'The main S&T objective of CATSENSE is to design novel high performance catalysts and biosensors by a new interactive approach combining i. the production of mono and bi-metallic gas-phase clusters of controlled homogeneity, ii. the extensive characterisation of their morphology, structure (ex and in situ) and optical properties, iii. theoretical modelling and screening, and iv. catalytic and biosensing laboratory tests. Prototypes of the most promising catalyst and biosensor will be tested in realistic operative conditions through intense collaboration with our industrial partners. Biosensing and Catalysis applications are of paramount importance in Europe nowadays and are directly related to core issues of the Renewed Lisbon strategy, i.e, Health and Environment, respectively. Combining these technologies in a new supra-discipline of cluster-based nanotechnology will allow CATSENSE to contribute to the challenges that nanotechnology is now facing in Europe: a poor commercialisation track record of new discoveries and a shortage of adequately trained professionals. The training program will deliver nanotechnology experts corresponding to the need of the job market through a multi-level interdisciplinary and intersectorial network. The balanced program combines local expert training by academia and industrial partners, a network-wide secondment scheme, and a dense seminar, workshop and school schedule.'";3938144,54;3938144,54;FP7-PEOPLE-2013-ITN;/MC-ITN;KATHOLIEKE UNIVERSITEIT LEUVEN;BE;"Teer Coatings Limited;THE UNIVERSITY OF BIRMINGHAM;TEL AVIV UNIVERSITY;DANMARKS TEKNISKE UNIVERSITET;UNIVERSITA DEGLI STUDI DI MILANO;UNIVERSITA' DEGLI STUDI DI MILANO-BICOCCA";"UK;IL;DK;IT";/LIF;1;0;0;1;0;0 110943;608184;SNAL;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-ITN;FP7;Smart Nano-objects for Alteration of Lipid-bilayers;2014-04-01;2018-03-31;;SNAL is a multidisciplinary programme specially designed to provide scientific and transferable skill training and career development for early stage researchers and experienced researchers in membrane research. Working in a multidisciplinary network will give the researchers a broad perspective on their research field as well as the basic ability of pursuing a research project from basic sciences to industrial applications. The broad aim is to train a new cohort of researchers with systemic thinking equipped with generic skills in combining experimental studies and computer simulations to prepare them for fruitful careers in academia and industry. One challenge for the project is the design and synthesis of novel biomaterials able to modify membrane properties. This requires deep understanding of the interactions of lipid membranes with nano-objects including functional biomimetic polymers, polymeric micelles, carbon nanotubes and polymer therapeutic complexes/conjugates to enable the intelligent design of novel materials with improved bilayer modifying properties. To achieve this goal we have assembled a highly interdisciplinary team of leading groups all having synergies in their established research interests in the field of lipid bilayer – nano-objects interactions. The project combines computer simulations, chemical synthesis, clinical and industrial expertise, physical and biological experiments. The industry involvement in the project is very high with full participation of Unilever and Biopharma, the companies from different sectors. Complementarity of partner skills provides a logical basis for a collective training programme. The full cycle of the design process, from theoretical models to synthesis and experimental and clinical validation, is of particular importance for training of ESRs and their future career development.;3645408,8;3645408,8;FP7-PEOPLE-2013-ITN;/MC-ITN;UNIVERSITAT ROVIRA I VIRGILI;ES;"BIOPHARMA TECHNOLOGY LTD;THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;THE UNIVERSITY OF MANCHESTER;IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE;JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;UNILEVER U.K. CENTRAL RESOURCES LIMITED;LEIBNIZ-INSTITUT FUR POLYMERFORSCHUNG DRESDEN EV";"UK;DE;FR";/LIF;1;0;0;1;0;0 110152;610897;GENFUEL;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IAPP;FP7;Addressing Fundamental Challenges in the Design of new generation fuels;2014-02-01;2018-01-31;;"There is a pressing need at the European and global levels to address challenges in the design of a new generation of fuels in order to achieve significant efficiency and emissions benefits in modern downsized boosted engines employing gasoline and ethanol blends. Abnormal combustion phenomena are a severe constraint to the use of much higher boosting pressures which are needed for significant gains in efficiency and reduction in emissions. These phenomena have to be better understood within the context of the different thermodynamic regimes that exist in these engines and addressed to enable the full benefit of modern downsized boosted engines to be realised. The area is vitally important for the reduction of GHG emissions and the resulting climate change impact of transportation. GENFUEL is an intersectoral collaboration that tackles fundamental challenges in understanding combustion mechanisms under highly boosted conditions that will be key to unlocking improvements in the design of a new generation of fuels. The project adopts a holistic approach with project components which study fuel engine behaviour along with safe handling technologies and life cycle analysis accounting for water use in fuel pathways. Long-term collaborative relationships will be established between Shell, the coordinator, and six partner universities. This will link their collective combustion, lifecycle and fuel handling expertise directly with Shell’s longstanding R&D fuel design capability. In the first two years, university researchers will participate via secondments to interdisciplinary R&D projects. Industry approaches to R&D will be conveyed to each university via the short term secondments of Shell researchers. To demonstrate commitment to a durable collaboration, Shell will pay for the cost of the researchers' reintegration year and the universities and Shell will jointly initiate follow-on or new projects. A lasting intersectoral collaboration will therefore be established.";1502213,34;1502213,34;FP7-PEOPLE-2013-IAPP;/MC-IAPP;SHELL RESEARCH LIMITED;UK;"NATIONAL UNIVERSITY OF IRELAND GALWAY;IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE;THE UNIVERSITY OF BIRMINGHAM;POLITECHNIKA WARSZAWSKA;WAGENINGEN UNIVERSITY;UNIVERSITEIT UTRECHT;UNIVERSITY OF ULSTER";"IE;UK;PL;NL";/LIF;1;0;0;1;0;0 188683;616179;PAST;ONG;FP7-IDEAS-ERC;ERC-CG-2013-SH6;FP7;Pre-Columbian Amazon-Scale Transformations;2014-07-01;2018-06-30;;'The protection of rainforests and the development of sustainable land-use practices in the humid tropics are of global significance because these forests represent a major reservoir of biodiversity and are of crucial importance for the regulation of Earth’s climate. A sound understanding of the historical role of humans in shaping Amazonian landscapes and to what extent Amazonian forests were resilient to historical disturbance is critical to make informed policy decisions about sustainable Amazonian futures. However, the nature and scale of pre-Columbian land use and its modern legacy on Amazonian landscapes are among the most debated topics in New World archaeology, palaeoecology and conservation. To resolve this debate, this project will investigate the influence of the late pre-Columbian (1000-1492 A.D.) land use on Amazonian landscapes, the impact of the 1492 Columbian Encounter (CE) and its modern legacy through the comparative study of pre-Columbian land uses in four different regions of Amazonia. It will apply, for the first time, an innovative interdisciplinary approach that integrates archaeology, ethnohistory, archaeobotany, paleoecology, soil science, landscape ecology and remote sensing (including the novel application of LIDAR survey) to the following study regions: (1) the Santarem Amazonian Dark Earth sites in the Lower Amazon, (2) the interfluvial areas of the Purus-Madeira Rivers in the Central Amazon, (3) the Acre geoglyphs of SW Amazonia and (4) the ring-ditches of the Baures forested areas of the Bolivian Amazon. The results of the project have broader implications not only for archaeology and geography but for conservation and sustainable Amazonian futures.';1723004,97;1723004,97;ERC-2013-CoG;/ERC-CG;THE UNIVERSITY OF EXETER;UK;;;"/SCI;/SOC";1;0;0;1;0;0 191260;618597;EMO;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-CIG;FP7;Happy or Sad? The Influence of Emotional Body Cues on Facial Expression Perception in Huntington’s Disease;2014-07-01;2018-06-30;;'Impaired emotion recognition is common in many neuro-psychiatric disorders, adding a devastating social toll to the already challenging symptoms. One such disorder is Huntington's disease (HD), a neurodegenerative progressive condition in which motor and cognitive symptoms are further complicated by impaired emotion recognition. Unfortunately, despite decades of research, the vast majority of work on HD studied emotion perception using artificially posed faces void of any context. Yet recent work has shown that subtle emotional body cues can completely overturn the perceived emotion in real life emotional faces. For example, in a recent report my colleagues and I demonstrated that without body context cues, perceivers cannot differentiate real-life highly intense positive and negative faces [Aviezer et al., Science, in press]. Thus, it is clear that traditional neuropsychological research on emotion perception in HD is dated and needs to be bridged with contemporary work in social psychology and social neuroscience. To this end, the current studies will take an interdisciplinary approach and examine the perceptual mechanisms of face-body interactions in HD. Study 1 will use eye scanning to examine how perceived emotional body cues alter the visual scanning of facial expressions in HD. Study 2 will use facial EMG to examine how the perceived emotional body cues influence the automatic motor mimicry to perceived facial expressions in HD. Finally, study 3, will use fMRI to examine the neural processes involved in face-body integration in HD. These ecological perceptual-emotional measures combined with genetic, neuroanatomical and functional imaging biomarkers of disease progression, will have the power to portray, for the first time, a deep understanding of the neuropsychological mechanisms underlying impaired facial expression recognition in HD.';100000;100000;FP7-PEOPLE-2013-CIG;/MC-CIG;THE HEBREW UNIVERSITY OF JERUSALEM;IL;;;/LIF;1;0;0;1;0;0 109185;608363;ABACUS;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-ITN;FP7;Advanced Integration of SDN and SDO for Future-Proof Networks;2013-09-01;2017-08-31;;"In the area of optical communications and networks, major research and development efforts are focused towards extending the flexibility and efficiency of optical networks; the main driver is to better adapt to new emerging bandwidth demanding services while catering the needs of end-users, while reducing the overall cost and complexity of the network. The goal of this project is to provide interdisciplinary training at the highest level in the area of optical communications and the novel areas of Software Defined Optics (SDO) and OpenFlow Software Defined Networking (SDN). In particular the training will contain the required new skills required to define novel, resilient, cost- and energy-efficient optical networks architectures achieving efficient flexible, reconfigurable, and dynamically-adaptive systems. At the end of this project, new concepts will be proposed and validated to achieve ultra high data rates (beyond 100 Gbps per wavelength), enhanced resource utilization and flexible bandwidth allocation at sub-wavelength granularities using SDO. Furthermore, new network management and networking solutions to flexibly control such network will be demonstrated using SDN. The three early stage researchers joining this European Industrial Doctorate program will hence become trained in a field of high importance within the roadmap of photonics development at industry level and vital importance for the strategic technology growth in Europe.";879166,87;879166,87;FP7-PEOPLE-2013-ITN;/MC-ITN;DANMARKS TEKNISKE UNIVERSITET;DK;ADVA OPTICAL NETWORKING SE;DE;/LIF;1;0;0;1;0;0 91890;235321;EMOTIONS IN INSOMNIA;ONG;FP7-PEOPLE;FP7-PEOPLE-IEF-2008;FP7;The neurobiological bases of emotion processing in Primary Insomnia;2009-04-04;2011-04-03;;We present an interdisciplinary project which aims to evaluate the neurobiological correlates of emotion processing in primary insomnia. The dimensional approach of emotions (e.g. Bradley, 2000) suggests that they can be described by referring to two dimensions: arousal and valence. In insomnia, while the role of arousal has been widely investigated, few studies have considered the valence. This study aims at evaluating both these dimensions, through a combination of psychological and neurobiological methods. Thirty people with primary insomnia (PI) and thirty good sleepers (GS) will watch neutral, negative and poor sleep-related pictures controlled for arousal and valence. During the task, brain activity will be recorded through functional magnetic resonance image (fMRI). Pictures will be presented within a blocked design. Cortisol levels will be measured to investigate differences between groups due to the quality of sleep. Increased cortisol release should be positively correlated with the severity of the symptoms of insomnia. With respect to the fMRI task, the PI should present an enhanced response to negative stimuli related and unrelated to sleep compared to GS. The innovative aspect of this project is the consideration of the valence dimension, and not only of the arousal dimension, when investigating the physiological correlates of emotions in people with insomnia. The aim is to investigate which neurobiological mechanisms intervene in the relation between the processing of the valence and of the arousal of the stimuli and the quality of sleep. This is expected to deepen the knowledge of insomnia and its relation with psychopathology. Results could have an impact on psychological treatment of insomnia, for example introducing strategies which aim at increasing the patient’s self-regulation of the emotional charge associated with sleep. Bradley (2000). In Cacioppo et al. (Eds.). Handbook of Psychophysiology, 2nd edition, Cambridge University Press.;;160996,91;FP7-PEOPLE-IEF-2008;/MC-IEF;UNIVERSITAETSKLINIKUM FREIBURG;DE;;;"/SCI;/EMP";1;0;0;1;0;0 109653;607415;RENESENG;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-ITN;FP7;RENESENG;2013-11-01;2018-03-31;;"RENESENG aims to prepare a new generation of highly-qualified researchers in Biorefinery and biobased chemicals Systems Engineering Sciences in Europe, expected to bear high impact in the design of newly establishing industrial complexes in biorefinering and more generally in eco-industries. The effort requires to bring together academic and industrial teams, with particularly interdisciplinary and high-quality expertise, embracing disciplines in agricultural sciences, chemistry and chemical eng., biology and biotechnology, computer science, process engineering, logistics and business economics, as well as social sciences with an emphasis on life cycle analysis skills. The principal scientific challenge of the network is to develop a program of inter-disciplinary research from expert groups with dedicated interests in biorenewables using a model-assisted systems approach as an integrating aspect, further capitalizing on its potential and role to address complex and large problems. The proposal brings state-of-the-art systems technologies mobilizing a critical mass in Europe that is already particularly active in this area but needs to coordinate the efforts and reduce fragmentation of knowledge. The aim is to develop and validate modelling, synthesis, integration and optimization technology addressing: 1)lignin-based and cellulosic processes2)water based paths to biomass production 3) waste treatment paths 4) combination of biorenewables processing with utilization of other renewable. In parallel RENESENG has developed a program of training activities including, development of communication, business, and social skills, visits and social events allowing to prepare a new profile of researchers able to transmit their knowledge in the next networking teams. RENESENG guaranties high quality careers perspective for all, through the active participation of 6 industrials, the creation of spin-offs and the sustainable implementation of a multicenter PhD training program.";4195076,17;4195076,17;FP7-PEOPLE-2013-ITN;/MC-ITN;NATIONAL TECHNICAL UNIVERSITY OF ATHENS - NTUA;EL;"ETHNIKO KENTRO EREVNAS KAI TECHNOLOGIKIS ANAPTYXIS;IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE;BIOPROCESS PILOT FACILITY BV;ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE;DANMARKS TEKNISKE UNIVERSITET;ARKEMA FRANCE SA;QUANTIS;COMPAGNIE INDUSTRIELLE DE LA MATIERE VEGETAL CIM V;UNIVERSITY OF SURREY;STICHTING WAGENINGEN RESEARCH";"EL;UK;NL;CH;DK;FR";/LIF;1;0;0;1;0;0 89713;221428;BOTRYTISGENOMICS;ONG;FP7-PEOPLE;PEOPLE-2007-2-1.IEF;FP7;Genomics of the Botrytis cinerea grapevine interaction;2009-01-01;2010-12-31;;The training objective of the proposed research is to complete the researcher’s existing knowledge in mycology and molecular biology by an interdisciplinary experience in infection physiology, genomics and modern bioinformatics, thus providing a boost for her career development and independence. The research objective of the project is to investigate fungal pathogenicity at the genomic level. The chosen model is the interaction between grapevine and grey mould because wine production plays an important role in European agriculture (several billion € market value), because grey mould is a major pathogen of this crop and because the high amounts of fungicides used to control the pathogen each year increase production cost and raise environmental issues. The genomes of the fungus B. cinerea and the plant V. vinifera have recently been sequenced, and the new available genomic tools should, for the first time, allow the drawing of an integrated view of the interaction between the pathogen and its host, and the deciphering of the largely unknown molecular mechanisms that support the fungus attack or the plant defence. As part of an effort to fully characterise the infection process, the aims of this project are 1) to identify the major fungal molecular players at work in the interaction between grapevine and B. cinerea and 2) the validation of these players in search of new targets for fungicides. Transcriptomic analyses of the infection will be performed using micro arrays, and a global profiling of the fungal genes will be obtained. Gene replacement will then be used to disrupt cellular functions highlighted by the genomics data, and analysis of the mutants will reveal the genes important in the infection process. This project should help develop control strategies that are novel, more efficient and/or environmentally safer. This project is lastly in harmony with the aims of the Community to structure EU research and to promote the participation of women in science.;224640,41;224640,41;FP7-PEOPLE-2007-2-1-IEF;/MC-IEF;UNIVERSITE LYON 1 CLAUDE BERNARD;FR;;;"/SCI;/EDU";1;0;0;1;0;0 90849;220108;SPIVOR;ONG;FP7-PEOPLE;PEOPLE-2007-4-2.IIF;FP7;Geometrical aspects of spin and vortex dynamics in electromagnetic and matter waves;2009-08-01;2011-07-31;;The project is intended to reveal a unifying nature and fundamental geometrical features of the spin and vortex dynamics of classical electromagnetic and quantum-mechanical matter waves. The Berry phase, Magnus effect, and spin-Hall effect are attracting ever-increasing interest of scientists because of their potential applications in nano-physics, spintronics, quantum computing, etc. Simultaneously, the modern optics (including nano-optics, photonics, and plasmonics) offers unique possibilities to test and apply fundamental quantum-mechanical ideas within classical systems. The striking similarities of the spin and vortex dynamics in electromagnetic and matter waves call for an in-depth theoretical analysis which will be given within the framework of the present project. We will carry out extensive theoretical investigations of the propagation and scattering of electromagnetic waves in inhomogeneous and anisotropic media. A special attention will be paid to dynamics related to spin (polarization) and orbital (optical vortices) angular momenta of light. The research will be concentrated on various manifestations of spin-orbit-type interactions between intrinsic and extrinsic degrees of freedom of electromagnetic waves and quantum particles. We aim to develop a unifying theoretical approach to be able to describe specific features of behaviour of spins and vortices evolving in external fields. The approach will include the fundamental geometro-dynamical effects: the Berry phase, spin-Hall effect, and Magnus effect. Using scope of the host laboratory, we are going to perform experimental test of fine manifestations of these effects in classical optics, with potential applications to fiber optics, metamaterials, and remote sensing of turbulent atmosphere. We anticipate that realization of the project will contribute to the ability to control complex wave fields of different nature and, thus, will have a profound interdisciplinary impact and applications.;183468,21;183468,21;FP7-PEOPLE-2007-4-2-IIF;/MC-IIF;NATIONAL UNIVERSITY OF IRELAND GALWAY;IE;;;"/SCI;/COO";1;0;0;1;0;0 106562;313014;ETAEARTH;ONG;FP7-SPACE;SPA.2012.2.1-01;FP7;Measuring Eta_Earth: Characterization of Terrestrial Planetary Systems with Kepler, HARPS-N, and Gaia;2013-01-01;2017-12-31;https://www.etaearth.eu/ETAearth/;We propose to carry out an FP7 collaborative project to provide the first ever quantitative answer to one fundamental age-old question of mankind: ‘How common are Earth analogs in our Galaxy?’. We will achieve our goal by combining the unprecedented photometric precision of NASA’s Kepler mission, the unrivalled precision of ground-based radial-velocities from the HARPS-N spectrograph, and ESA’s Gaia mission exquisitely accurate parallaxes. Ours is a transnational collaboration between European countries and the US setup to optimize the synergy between space- and ground-based data whose scientific potential can only be fully exploited when analyzed together. We ask for manpower and resources to carry out a GTO program with HARPS-N@TNG (80 nights/yr for 5 years) to measure dynamical masses of terrestrial planet candidates identified by the Kepler mission. With the unique combination of Kepler and HARPS-N data we will learn for the first time about the physics of their interiors. Some of these planets will have characteristics (masses, radii) similar to Earth, and they might be orbiting within the habitable zone of stars much like our Sun. We will search for planets similar to Earth orbiting a carefully selected sample of nearby bright solar-type stars and red M dwarfs, providing suitable candidates for spectroscopic characterization of their atmospheres with next-generation space observatories. We will combine Kepler, HARPS-N, and Gaia data products of stars in the Kepler field to underpin the occurrence rates of terrestrial planets (??) as a function of stellar properties with unprecedented accuracy. Our unique team expertise in observations and modelling of exoplanetary systems will allow us to fully exploit the potential for breakthrough science intrinsic to this cutting-edge, multi-techniques, interdisciplinary project, making the best use of data of the highest quality gathered from NASA and ESA space missions and ground-based instrumentation.;2957200;1994359;FP7-SPACE-2012-1;/CP-FP;ISTITUTO NAZIONALE DI ASTROFISICA;IT;"UNIVERSITE DE GENEVE;THE UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS;UNIVERSITA DEGLI STUDI DI PADOVA;THE QUEEN'S UNIVERSITY OF BELFAST;THE UNIVERSITY OF WARWICK;SMITHSONIAN INSTITUTION;THE UNIVERSITY OF EDINBURGH";"CH;UK;IT;US";/SCI;1;0;0;1;0;0 103162;295375;PERSIA;ONG;FP7-IDEAS-ERC;ERC-AG-SH6;FP7;Persia and its Neighbours: the Archaeology of Late Antique Imperial Power in Iran;2012-05-01;2018-04-30;;"The Sasanian Empire (3rd-7th c. AD) stretched from Mesopotamia to the west of the Indian Subcontinent. A pilot study has shown that major frontier walls and geometrical fortifications, whose scale and sophistication surpasses those in contemporary Europe, date to the Sasanian era, as do grand urban foundations and canal systems. Yet, excavations and surveys of Sasanian monuments have been far and few between and have mostly employed conventional approaches. Publications amount to a fraction of those on Roman studies. Our interdisciplinary project will provide unique insights into one of the great powers of the age, but the one that is most poorly understood. It will achieve this by bringing together a broad range of complementary methods. Satellite images will be analysed to examine the Empire’s frontier zones. Key sites will be selected for geophysical survey, targeted excavation, scientific dating and systematic analysis of artefacts, faunal and botanical remains. Combining large-scale survey with small-scale case studies promises to provide unrivalled insights into military infrastructure, urbanisation and rural settlement – intertwined phenomena, as agricultural surplus production enabled large-scale construction projects. Our in-depth study of Sasanian frontier territories promises to fill a major gap in our understanding of Late Antiquity and shed light on the reasons behind the longevity, economic and military dominance and dynamism of one of the largest empires of the ancient world, far beyond what has been achieved so far. The Empire’s capabilities challenge our traditional Eurocentric approach. While it is acknowledged that the later Caliphate’s military power and urban culture were unrivalled in Western Europe at the time, our project promises to show that some of these advances have their roots in the pre-Islamic era. Our project will open up new fields of research, and will have a major impact on archaeological studies and ancient and medieval history.";2488003;2488003;ERC-2011-ADG_20110406;/ERC-AG;THE UNIVERSITY OF EDINBURGH;UK;"UNIVERSITY OF DURHAM;THE UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS;UNIVERSITE D'AIX MARSEILLE;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;UNIVERSITY OF BRADFORD";"UK;FR";/SOC;1;0;0;1;0;0 109828;607690;UNIVACFLU;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-ITN;FP7;Universal Flu Vaccine;2013-11-01;2018-02-28;;"Currently licensed influenza vaccines promote an effective antibody response, but only against influenza virus strains that antigenically match the vaccine composition. Little protection is induced by these vaccines against antigenically drifted strains such as those emerging from an avian or swine reservoir. Hence there is a great need to develop broadly cross-reactive flu-vaccines. The aim is to establish a European training platform to integrate young researchers in a highly innovative interdisciplinary strategy to develop mucosal flu-vaccines. The Universal Influenza Vaccine (UNIFLUVAC) network is aimed at harnessing the expertise of the most accomplished vaccine researchers, developers and regulators in Europe in a timely and multidisciplinary training approach unparalleled in any single EU country. The training program is extensive and builds on the integrated added values of complementing expertise and the full access to state-of-the- art technologies and excellent training environments. This unique consortium has 2 SMEs as fully committed members to guarantee strong intersectoral cooperation between industry and academia. The partners represent 6 leading universities in 6 different member countries, securing excellent presence in Europe. The structure of UNIFLUVAC is specifically adapted to operate over the whole range of specialized expertise needed. Specifically, UNIFLUVAC provides vaccine antigen identification and expression, adjuvant design and formulation, testing in state-of-the-art preclinical animal models and finally clinical safety, immunogenicity and efficacy trials in excellent and for Europe unique medical centres. This is the strength and appeal of the UNIFLUVAC proposal. It will also establish a long-term European network based on a new cohort of young professionals with excellent employability and career opportunities in academic, clinical or industrial settings. UNIFLUVAC will have a major impact on human health in Europe and globally.";4116701;4116701;FP7-PEOPLE-2013-ITN;/MC-ITN;GOETEBORGS UNIVERSITET;SE;"MIVAC DEVELOPMENT AB;ISTITUTO EUROPEO DI ONCOLOGIA SRL;UNIVERSITE DE LILLE II - DROIT ET SANTE;VIB;UNIVERSITAETSKLINIKUM FREIBURG;RETROSCREEN VIROLOGY LTD;KING'S COLLEGE LONDON";"SE;IT;FR;BE;DE;UK";/LIF;1;0;0;1;0;0 106543;309962;HYDROZONES;ONG;FP7-NMP;NMP.2012.2.2-1;FP7;Bioactivated hierarchical hydrogels as zonal implants for articular cartilage regeneration;2013-01-01;2017-12-31;http://www.hydrozones.eu/;"Degeneration of cartilage is a major cause of chronic pain, lost mobility and reduced quality of life for millions of European citizens. From a clinical point of view treatment to achieve cartilage regeneration (hyaline) and not only repair (fibrous) remains a great challenge. No clinical therapy is available that leads to healing of cartilage defects. Current cartilage implants cannot establish the hierarchical tissue organisation that appears critical for normal cartilage function. We hypothesise that a biomimetic zonal organisation is critical for implants to achieve cartilage regeneration. HydroZONES represents an interdisciplinary consortium that adopts a strategy to regenerate, rather than repair, articular cartilage based on the tissues zonal structure and function. HydroZONES will use advanced bioprinting technology for fabrication of 3D biofunctional hydrogel constructs, eventually mechanically reinforced by degradable polymer scaffolds, as biomimetic reconstitution of the zonal organisation of natural cartilage. Constructs will be optimized for cell-free application and also for combination with chrondrogenic cells (chondrocytes and/or MSC). Stringent in vitro and long term in vivo testing of the constructs will be employed that will yield a new clinical standard for pre-clinical testing. Cutting edge 3D tissue models and bioreactor technology will be used together with in silico modelling to develop a predictive in vitro assay and test system that will be validated against the in vivo data. Installation of a quality and regulatory affair management system, GMP production, accredited in vitro testing and involvement of clinical partners and companies with experience in clinical trials ensures that the best performing construct will be brought into an optimal position for entering clinical trials at project end. HydroZONES will thus advance the European Union as world leader in the field of joint cartilage regeneration.";13243737,61;9749700;FP7-NMP-2012-LARGE-6;/CP-IP;UNIVERSITAETSKLINIKUM WUERZBURG - KLINIKUM DER BAYERISCHEN JULIUS-MAXIMILIANS-UNIVERSITAT;DE;"QUEENSLAND UNIVERSITY OF TECHNOLOGY - QLD QUT;INSTITUTO POLITECNICO DE LEIRIA;CELLCOTEC BV;LIFETEC GROUP BV;STICHTING PROTOSPACE;POLYVATION BV;UNIVERSITAIR MEDISCH CENTRUM UTRECHT;UNIVERSIDAD DE NAVARRA;GABO:MI GESELLSCHAFT FUR ABLAUFORGANISATION:MILLIARIUM MBH & CO KG;ARTTIC;MICHAEL HUBERT BARFUSS;UNIVERSITAETSKLINIKUM HEIDELBERG;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;UNIVERSITEIT UTRECHT;JULIUS-MAXIMILIANS-UNIVERSITAT WURZBURG;LEIBNIZ-INSTITUT FUR POLYMERFORSCHUNG DRESDEN EV";"AU;PT;NL;ES;DE;FR;UK";/SCI;1;0;0;1;0;0 104773;307998;SIREAL;ONG;FP7-IDEAS-ERC;ERC-SG-PE10;FP7;"Seismology in the ionosphere? This is REAL! Ionosphere as a natural indicator of numerous geophysical events";2012-10-01;2018-06-30;;"We propose to perform a wide spectrum of ionosphere-related research, from ionosphere seismology to ionospheric storms and GNSS/GPS performance during extreme ionospheric and space weather events. The main focus will be made on such rare subject as ionosphere seismology that aims to study ionosphere response to large earthquakes, to investigate the main properties of different kinds of ionospheric disturbances occurred due to seismic and seismic-like events, including tsunamis, volcano eruptions and explosions. The 11/03/2011 Tohoku megaquake has opened new challenges for modeling of co-seismic effects and has indicated new directions for further research. In particular, we found that the ionosphere is able of showing images of a seismic fault slip rupturing about ~8 minutes after an earthquake, which opens new opportunities for short-time tsunami warnings. In addition to the ionosphere seismology, the project includes fundamental multi-instrumental studies of the global dynamics of the ionosphere under geomagnetically disturbed and quiet conditions. Great attention will be paid on investigation of features of traveling ionospheric disturbances and on the ionosphere behavior during variations of interplanetary parameters such as magnetic field (IMF) and electric field (IEF). The latter is directly connected to the last subject of our proposal - solar- and ionosphere-induced GPS -failures. The main advantages for Europe coming with this project are: 1) a highly interdisciplinary project on a sufficiently new branch of the science and with rare applications; 2) extension of the fundamental ionosphere studies in Europe that will increase the competitiveness of Europe among other world-famous research schools on the Earth’s ionosphere; 3) the results of our work on GNSS operation quality will be useful for the future Galileo mission as well, and would help to improve the system.";858000;858000;ERC-2012-StG_20111012;/ERC-SG;INSTITUT DE PHYSIQUE DU GLOBE DE PARIS;FR;;;"/PSE;/ENV;/EAR";1;0;0;1;0;0 103919;291585;T-FORCES;ONG;FP7-IDEAS-ERC;ERC-AG-PE10;FP7;Tropical forests in the changing earth system;2012-07-01;2018-06-30;;"The ambition of this proposal is to determine, from the ground up, the changing role of tropical forests in the global carbon cycle. The scientific objectives are: (1) Determine the trajectory of change in remaining tropical forests, (2) Unravel the drivers of change, (3) Gauge the sensitivity of forests to the climate change threat, and (4) Scale the findings to the present and future earth system. The 5-yr interdisciplinary research project led by Oliver Phillips will construct a Pan-Tropical Observatory of Forest Function, using this to reveal the transient and long-term forest response to global change. In Asia, Africa, Australia, and South America, T-FORCES will direct long-term on-the-ground observations of forest dynamics, and integrate them with complementary approaches including high frequency measurement of the climate-sensitivities of different components of the carbon cycle, and full analysis of forest climate, landscape, and ecology. The huge scale of the tropical forest biome will be used to develop a series of natural experiments: *Within continents, gradients of climate, soil, and disturbance will be sampled to explore current, transient responses and to scale-up in space and time. *Six elevational gradients will provide replicates to reveal the equilibrium sensitivities of tropical carbon cycle processes to temperature. *By working across four tropical continents each provides independent tests to distinguish between change drivers that may be regional (eg Amazon drought) or global (eg CO2 fertilisation) in nature. T-FORCES will transform scientific understanding of tropical forests in the global carbon cycle, by revealing the key patterns, impacts and processes so far, the threat to forests from global change, and the risk that forests will magnify those changes. The Pan-Tropical Observatory of Forest Function will provide the global science community with the baseline and framework to investigate the processes involved throughout our century.";2500000;2500000;ERC-2011-ADG_20110209;/ERC-AG;UNIVERSITY OF LEEDS;UK;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;UK;"/PSE;/ENV;/EAR";1;0;0;1;0;0 108752;323677;KFI;ONG;FP7-IDEAS-ERC;ERC-AG-SH2;FP7;"""KNOWING FROM THE INSIDE: ANTHROPOLOGY, ART, ARCHITECTURE AND DESIGN""";2013-06-01;2018-05-31;;'This project promises to reconfigure the relation between the practice of academic inquiry in the human sciences and the knowledge to which it gives rise. Conventional research protocols expect the scholar to treat the world as reserve from which to draw empirical material for subsequent interpretation in light of appropriate theory. Against this, we will establish and trial an alternative procedure whereby theory is not applied after the fact, to a corpus of material already gathered, but rather grows from our direct, practical and observational engagements with the stuff of the dwelt-in world. Theoretical thinking, then, is embedded in observational practice, or knowing in being, rather than vice versa. This way of knowing, by studying with things or people instead of making studies of them, has long been key to anthropology. It is also, however, central to arts practice, as it is to the contingent disciplines of architecture and design. All four disciplines offer paths to knowing-in-being which challenge the division between data gathering and theory building that underwrites normal science. By bringing them together, this project will customise this general approach to knowing to specific contexts of practice including landscape management, craft heritage, environmental conservation, building and restoration, drawing and notation. Our method will be distinguished by observation and experiment, the outcomes of which will be not just written texts but works of art or craft, performances and installations. The project will contribute to both education and design for sustainable living through a renewed emphasis on the improvisational creativity and perceptual acuity of practitioners. It will promote the dissemination of knowledge through shared experience, and advance a new view of interdisciplinarity as an intertwining of lines of interest.';2434878,4;2434878,4;ERC-2012-ADG_20120411;/ERC-AG;THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN;UK;;;/SOC;1;0;0;1;0;0 106954;324247;Momentum;ONG;FP7-IDEAS-ERC;ERC-AG-SH2;FP7;"Modeling the Emergence of Social Complexity and Order: How Individual and Societal Complexity Co-Evolve";2013-06-01;2018-05-31;;This proposal develops a new perspective on social systems by combining analytical sociology with evolutionary game theory, agent-based modeling, computational social science, complexity science, and experimental research. Our focus on co-evolutionary processes will shed new light on emergent phenomena in social systems and elaborate a “social ecosystem” perspective. We will overcome problems of previous approaches by implementing social mechanisms, learning rules, and parameters in an evolutionary way. Our major goal is to show how a “homo socialis” can emerge as the result of an evolutionary competition. For this, we will demonstrate that strict payoff maximization or mechanistic, stimulus-response interactions may eventually be replaced by other-regarding behaviors. In particular, we will study how social cooperation and social norms emerge from repeated social interactions. We will furthermore equip agents with small virtual “brains” and simulate the co-evolution of individual and societal complexity. This will add cognitive complexity to our modeling approach and allow us to study origins and effects of subjectivity, but also early stages in human social evolution. We plan to demonstrate that, in a complex society, boundedly rational agents can perform equally well as a perfect “homo economicus”, and that both types of agents emerge and spread under different conditions. Our project is broad and highly interdisciplinary. It combines various methodologies and pursues an innovative complexity science approach to solve long-standing scientific puzzles. It has the potential to bridge previously incompatible research traditions by revealing unexpected and seemingly paradoxical relationships between them. Thereby, it will help to overcome existing controversies and the related fragmentation in the social sciences.;2498831;2498831;ERC-2012-ADG_20120411;/ERC-AG;EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH;CH;;;/SOC;1;0;0;1;0;0 108234;311335;SEQ-CYTOTOX;ONG;FP7-IDEAS-ERC;ERC-SG-LS6;FP7;Next generation sequencing for detection of human primary immunodeficiency syndromes characterized by impaired cytotoxic lymphocyte function;2013-05-01;2018-04-30;;Human primary immunodeficiencies affecting cytotoxic lymphocyte function are associated with high morbidity and mortality. They often present as hyperinflammatory syndromes triggered by viral infections, hematological malignancies, or systemic autoimmunity. Although recent advances have provided molecular diagnoses for some of the most severe cases, only a handful of genes have been identified and disease in a majority of patients cannot be explained by current insights. My work has elucidated fundamental mechanisms of lymphocyte cytotoxicity. Furthermore, my group is leading international efforts in developing sensitive assays of human lymphocyte cytotoxicity. Some of our assays have been implemented for clinical diagnostics world-wide. Recently, we have also identified new, widespread mutations that explain many cases of fatal immunodeficiencies early in life. We now seek support for taking such studies to yet a higher level. The outlined interdisciplinary approach presented here aims at evaluating cytotoxic lymphocyte development and function in large numbers of patients, in addition to healthy individuals in a complementary approach, using state-of-the-art methodology. We will employ next-generation sequencing to identify novel genes associated with disease. The significance of putative mutations for lymphocyte cytotoxicity will be assessed using cutting-edge experimental platforms. Together, such genotype-immunotype studies promise to reveal novel genes associated with disease and further provide understanding of human genetic diversity. Thus, these studies can directly benefit patients through improved diagnosis, aiding targeted treatments, and offer new insights into human cytotoxic lymphocyte development and function with relevance to health. Insights will also pave the way for prospective, population-based molecular epidemiology studies required to more accurately assess the panorama of diseases associated with congenital defects in lymphocyte cytotoxicity.;1499996;1499996;ERC-2012-StG_20111109;/ERC-SG;KAROLINSKA INSTITUTET;SE;;;"/BIO;/LIF;/MED";1;0;0;1;0;0 190002;631773;ImmunoTension;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-CIG;FP7;Inflammation and Immunity in Human Hypertension and Vascular Dysfunction;2014-05-01;2018-04-30;;Hypertension is a major cause of death and disability in Europe and in the rest of the World. It affects 30% of adults, and additional 30% are at very high risk of developing hypertension. This is an enormous health problem as it is a cause of subsequent renal failure, stroke, myocardial infarction and heart failure. Despite extensive research, the mechanisms of most cases of hypertension remain unclear. In spite of therapies available, over 40% of treated patients do not reach treatment goals and present with uncontrolled disease. Since the mid-1980s, no new classes of drugs have been successfully developed to treat hypertension. We and others have recently made observations providing a novel mechanism for hypertension involving activation of the immune system, with involvement of T lymphocytes, monocytes and dendritic cells. Mice lacking T cells or monocytes are protected from severe hypertension and renal/vascular dysfunction. Perivascular and renal infiltration of these cells producing cytokines such as IL-17 and TNF-alpha has been implicated. The exact mechanisms or relevance of these observations for human hypertension is unclear. Therefore, we propose to investigate the involvement of the immune system in human hypertension. First, we propose to analyse in depth the characteristics of leukocytes in hypertensive patients in comparison to normotensive controls. Subsequently we will focus on leukocytes infiltrating perivascular adipose tissue and cortex and medulla of the kidney in hypertension in relation to detailed clinical phenotypes of the disease such as ambulatory blood pressure monitoring or vascular dysfunction. Subsequently we will perform ex vivo functional studies by co-incubation of reporter vessels with hypertensive T cells (other leukocytes) to examine their role in vascular dysfunction. These interdisciplinary studies of hypertension have the potential of providing a new understanding and possibly treatment of this otherwise devastating disease.;100000;100000;FP7-PEOPLE-2013-CIG;/MC-CIG;UNIVERSITY OF GLASGOW;UK;;;/LIF;1;0;0;1;0;0 107427;320598;3D-E;ONG;FP7-IDEAS-ERC;ERC-AG-PE8;FP7;3D Engineered Environments for Regenerative Medicine;2013-04-01;2018-03-31;;"'This proposal develops a unified, underpinning technology to create novel, complex and biomimetic 3D environments for the control of tissue growth. As director of Cambridge Centre for Medical Materials, I have recently been approached by medical colleagues to help to solve important problems in the separate therapeutic areas of breast cancer, cardiac disease and blood disorders. In each case, the solution lies in complex 3D engineered environments for cell culture. These colleagues make it clear that existing 3D scaffolds fail to provide the required complex orientational and spatial anisotropy, and are limited in their ability to impart appropriate biochemical and mechanical cues. I have a strong track record in this area. A particular success has been the use of a freeze drying technology to make collagen based porous implants for the cartilage-bone interface in the knee, which has now been commercialised. The novelty of this proposal lies in the broadening of the established scientific base of this technology to enable biomacromolecular structures with: (A) controlled and complex pore orientation to mimic many normal multi-oriented tissue structures (B) compositional and positional control to match varying local biochemical environments, (C) the attachment of novel peptides designed to control cell behaviour, and (D) mechanical control at both a local and macroscopic level to provide mechanical cues for cells. These will be complemented by the development of (E) robust characterisation methodologies for the structures created. These advances will then be employed in each of the medical areas above. This approach is highly interdisciplinary. Existing working relationships with experts in each medical field will guarantee expertise and licensed facilities in the required biological disciplines. Funds for this proposal would therefore establish a rich hub of mutually beneficial research and opportunities for cross-disciplinary sharing of expertise.'";2486267;2486267;ERC-2012-ADG_20120216;/ERC-AG;THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;UK;;;"/PSE;/MAT;/IND;/CON";1;0;0;1;0;0 109993;612237;MHIVEC;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IAPP;FP7;Mid-High Frequency Modelling of Vehicle Noise and Vibration;2013-09-01;2017-08-31;http://www.inutech.de/mhivec/;"The control (and avoidance) of vehicle noise and vibration (NV) provides a crucial competitive advantage for car manufacturers due to the drive for lower noise pollution levels and enhanced driving comfort. NV issues can seriously detract from the reputation of a vehicle with a knock-on detrimental effect for the entire brand. As the automotive industry moves towards virtual prototyping, the simulation and modelling of vehicle NV is becoming increasingly important. Providing accurate numerical predictions in this area is an extremely challenging task. A detailed analysis of the structural vibrations on very fine scales is required, and small parameter changes can lead to large shifts in the frequency response function for a given vehicle. The wide range of materials and intricate couplings between different components provide enormous challenges for the NV simulation of a full vehicle, especially in the range of frequencies above 500Hz. Robust and efficient NV modelling techniques are, however, urgently needed by vehicle manufacturers for cutting costs by removing the need to develop expensive physical prototypes. The range of existing techniques addressing NV issues as part of the Computer Aided Engineering (CAE) toolkit is not adequate. The methods are not robust for frequencies over 500Hz and do not naturally fit into the simulation environment of CAE, where structural data are provided via mesh specifications. Only recently have these problems been overcome through new solution techniques developed and tested by the academic members of this project. Together with two specialized SMEs and the car manufacturer Jaguar Land Rover, this interdisciplinary and inter-sectoral consortium will develop the first black-box and mesh based tool for the vibro-acoustic analysis of a full vehicle body. This will catapult noise and vibration analysis from the research and development stage to a fast and reliable everyday tool for the engineering practitioner.";1944975,26;1944975,26;FP7-PEOPLE-2013-IAPP;/MC-IAPP;THE NOTTINGHAM TRENT UNIVERSITY;UK;"CDH AG;UNIVERSITY OF SOUTHAMPTON;inuTech GmbH;THE UNIVERSITY OF NOTTINGHAM";"DE;UK";/LIF;1;0;0;1;0;0 94205;237228;TRECC;ONG;FP7-PEOPLE;FP7-PEOPLE-IOF-2008;FP7;Tree Range Evolution under Climate Change;2010-02-01;2012-05-23;;"Ongoing global warming impacts species' biology, with some species showing population extinction, others displacing their distributional range and/or modify their phenology, either through phenotypic plasticity or genetic modifications. This two-year project aims at evaluating how changing climatic conditions will modify the distributional range of tree species, taking adaptation into account. More specifically, the following questions will be addressed: (1) under which conditions will distribution ranges move, and at what speed? (2) will populations at the low-latitude edge of the distribution survive, adapt or go extinct? This will be done through the combined use of two existing approaches: theoretical and process-based modelling. Theoretical approaches taking into account genetic and environmental variability, migration, gene flow and adaptation have been developed to predict the width of a species' range, but they remain hard to parameterize for use in the real world. Process-based models rely on biological observations, and can be used to predict species' ranges under given environmental conditions; however, they do not yet take evolution into account. The candidate will (1) develop a spatially explicit theoretical model of species' range evolution, including the effects of drift (stochasticity due to finite populations); (2) calibrate this model using existing data, and the fitness values predicted by the process-based model, on well-studied tree species in a first instance, and modify the process-based model so that it can take into account individual variability and trait evolution, for further use with other species. This work will enhance collaboration between two leading laboratories, and strengthen the links between ecologists and evolutionary biologists. Furthermore, the candidate will acquire competence in modelling, which will complete her interdisciplinary training and facilitate her integration as a researcher in the host country.";158133,51;158133,51;FP7-PEOPLE-IOF-2008;/MC-IOF;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FR;;;"/COO;/EDU";1;0;0;1;0;0 95457;254339;POMHYDCAT;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IOF;FP7;Coupled Polyoxometalate – Hydrogenase Catalysts for Photocatalytic Water Splitting;2010-09-15;2013-09-14;;"Alternatives to fossil fuels are of rapidly increasing importance, driven by concerns over energy security, cost, and global warming. In response to these concerns, the EU has set the target of obtaining 20% of all energy from renewable sources by 2020. A key challenge in renewable energy is finding an efficient way to convert plentiful solar energy into a source of chemical energy which can be stored, used for applications such as transportation, and consumed without releasing carbon dioxide – that is, a means of using solar energy to split water into molecular hydrogen and oxygen. This fellowship aims to develop a novel approach to complete water splitting, taking an interdisciplinary approach that combines recent breakthroughs in polyoxometalate-based water oxidation catalysts and enzymatic hydrogen evolution catalysts. The proposed hybrid systems will be among the first complementary polyoxometalate-enzyme catalysts; they also promise to become the first molecular catalytic systems to efficiently split water under visible light irradiation in mild conditions.";242927,8;242927,8;FP7-PEOPLE-2009-IOF;/MC-IOF;UNIVERSITY OF EAST ANGLIA;UK;UNIVERSITY OF GLASGOW;UK;"/LIF;/EDU";1;0;0;1;0;0 186793;630988;AMEMM;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-CIG;FP7;"""Assembly, Mechanism, and Evolution of Macromolecular Machinery""";2014-05-01;2018-04-30;;'Life has evolved many molecular machines to perform mechanical tasks. Studying these machines promises insights into how machinery can generate force, how they assemble themselves, and how they evolved from simpler components. Ultimately this knowledge may inform synthetic biology projects to redesign existing, or evolve novel, machinery. Yet these insights have been hindered by our inability to visualize these machines as they occur in situ. The emergent technique of electron cryo-tomography, however, offers the ability to image this molecular machinery in situ, and will likely form the basis of much research on these machines due to its ability to resolve individual proteins within frozen living cells in three dimensions. Here I describe interdisciplinary work to dissect macromolecular machinery and understand its function and evolution using as 'testing ground' one of the most striking examples of molecular machinery, the bacterial flagellar motor. The flagellar motor is attached to a long filament that it spins to form a helical propellor, pushing the bacterium in favourable directions. Yet although the motor's many components and cellular role are known, the molecular mechanism of rotation and self-assembly remain enigmatic, and while its ancestry is established, how additional proteins are recruited to form novel machinery is poorly understood. Pseudo-atomic models of motors in situ will be generated using electron cryo-tomography together with development of tagging techniques to locate proteins. These structures will next be related to their mechanical output using single-molecule biophysical methods to understand the mechanical contributions of components. Finally, fundamental principles of the evolution of macromolecular machinery will be explored, both by studying recent elaborations upon motors in some bacteria, and by studying convergent evolution by the unrelated – yet analogous – archeaellum.';100000;100000;FP7-PEOPLE-2013-CIG;/MC-CIG;IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE;UK;;;/LIF;1;0;0;1;0;0 105986;321580;ERANID;ONG;FP7-SSH;SSH.2012.3.2-4;FP7;"European Research Area Network on Illicit Drugs - Towards integrated European research in illicit drugs: cause and nature of drug problems; interventions and policies";2013-01-01;2017-06-30;http://www.eranid.eu/;"ERANID, the European Area Network on Illicit Drugs, aims to improve cooperation in drug research in order to allow well-founded policy decisions. ERANID works both in the demand field and in the supply field. ERANID will promote multidisciplinary research activities in the field of socio-economic sciences and humanities. This may cover e.g. emerging drugs, vulnerable groups, changing demographics of drug using populations, and the impact of drugs on health inequalities and social deprivation. It may also cover patterns in drug markets and the drug-crime nexus. Closer cooperation between researchers in different countries will also lead to a further development of research methodologies, which can be of special importance for the evaluation of policies and programmes. Overcoming fragmentation in drug research and developing a common Strategic Research Agenda (SRA) are key objectives of ERANID. To do this, ERANID will first take stock of research programmes and research projects. By making the results of this exercise easily accessible, ERANID will help researchers and policy makers to find information and avoid unnecessary duplication of research. ERANID will consult stakeholders (e.g. scientific community, treatment centre organisations, patient organisations, police and justice). Analysis of the results will help to find gaps and to set priorities for research that will profit most from an international and interdisciplinary approach. Bringing together funding bodies in EU Member States and other countries, involving policy makers and other stakeholders will help to create consensus about the research priorities. These issues will all inform the SRA, from which the priorities for two joint research calls will be selected. ERANID starts as a consortium of eleven partners from six EU Member States. Other organisations from a number of European and other countries will be kept closely informed and associated to this initiative. ERANID is meant as first step towards a longer term cooperation in the field of drugs research.";2221128,91;1999725;FP7-ERANET-2012-RTD;/CSA-CA;ZORGONDERZOEK NEDERLAND ZON;NL;"PRESIDENZA DEL CONSIGLIO DEI MINISTRI.;SERVICO DE INTERVENCAO NOS COMPORTAMENTOS ADITIVOS E NAS DEPENDENCIAS;INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE;MINISTERIE VAN VOLKSGEZONDHEID, WELZIJN EN SPORT;LIVERPOOL JOHN MOORES UNIVERSITY;Department of Health england;INSTITUTO DA DROGA E DA TOXICODEPENDENCIA;SERVICE PUBLIC FEDERAL DE PROGRAMMATION POLITIQUE SCIENTIFIQUE;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;OBSERVATOIRE FRANCAIS DES DROGUES ET DES TOXICOMANIES GIP*OFDT;HOME OFFICE";"IT;PT;FR;NL;UK;BE";/SCI;1;0;0;1;0;0 88851;223137;FUTURESYSBIO;ONG;FP7-HEALTH;HEALTH-2007-2.1.2-6;FP7;Tackling the future challenges in Systems Biology;2008-08-01;2012-01-31;;The emerging field of Systems Biology is anticipated to have a major impact on the biosciences, moving biology from a phenomenological to a predictive science. Such predictive ability should allow to accurately foresee the outcome of therapeutic interventions with individual patients or to optimise industrial bioprocesses more precisely than has been possible before. Therefore, the results of Systems Biology are expected to have major impact on treatment and diagnosing diseases, health care and the bio-industries. Developing the research field and ensuring exploitation of its results therefore is of major social and economic interest for the European Union. The overall objective of FutureSysBio is to spur and structure the discussion on the development of Systems Biology and thereby provide guidance to stakeholders and scientists. Specifically, the objectives of this project are: (1) To gather and update the research community on latest developments in Systems Biology. (2) To inform and guide funding organisations. (3) To inform and guide pharmaceutical and bio-industries in Europe on developments and opportunities in Systems Biology and thereby enable well-informed corporate decisions. (4) To inform and guide higher education and education funders of challenges and opportunities in interdisciplinary education and training. (5) To inform the media, policy makers and the general public of opportunities, challenges and facts in Systems Biology. To achieve these goals the consortium will organise the following highly visible events: (1) The International Conference on Systems Biology ICSB2008 in Gothenburg. (2) The International Conference on Systems Biology ICSB2010 in Edinburgh or Barcelona. (3) Six high-level expert workshops. (4) Two high-level topical conferences. Different types of dissemination activities tailored for the target audiences will ensure the significant impact that FutureBioSys plans to make on the future development of Systems Biology.;560748;500000;FP7-HEALTH-2007-B;/CSA-SA;GOETEBORGS UNIVERSITET;SE;CHALMERS TEKNISKA HOEGSKOLA AB;SE;"/BIO;/COO";1;0;0;1;0;0 95389;252926;SALINAME;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IEF;FP7;Self-assembly of magnetic core-shell nanoparticles at liquid-liquid interfaces for the fabrication of ultra-thin responsive membranes;2010-07-01;2012-06-30;;The goal of this project is to study and control the self-assembly of superparamagnetic iron oxide nanoparticles (NPs) stabilized by a shell of responsive polymers at liquid-liquid interfaces in order to crosslink them into ultra-thin, mechanically stable, responsive membranes. This novel “smart” material will have unique properties suitable for applications in miniaturized lab-on-chip and other microfluidics devices. The interdisciplinary nature of the project contributes to its scientific novelty and impact, and constitutes an extraordinary training experience for the applicant. In the first part of the project, the applicant will develop a novel combination of experimental techniques to characterize the fundamental aspects of core-shell NP adsorption at liquid-liquid interfaces. By means of advanced confocal microscopy and particle tracking, complemented by pendant-drop tensiometry, this project will yield an exhaustive characterization, both from a microscopic and macroscopic point of view, of such system, so far practically unexplored. The obtained understanding - of high scientific relevance in its own right - will be used to optimize the design and fabrication of crosslinked responsive NP monolayer membranes. Using superparamagnetic NPs stabilized by a shell of crosslinkable thermoresponsive polymers, the applicant will produce ultra-thin robust assemblies which can respond reversibly to external stimuli. Temperature changes and consequent responses can be imparted to the system locally by exploiting the magnetic functionality of the NP constituents (heat transfer in an AC magnetic field). Moreover the crosslinked membranes can be actuated in DC magnetic fields as envisaged for applications. The responsive properties of the resulting materials, which have no current equivalent, will be investigated by means of optical and atomic force microscopy (structural properties) and microrheology and colloid-AFM force spectroscopy (mechanical properties).;173065,2;173065,2;FP7-PEOPLE-2009-IEF;/MC-IEF;EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH;CH;;;"/SCI;/EDU;/ITT";1;0;0;1;0;0 95328;253532;RIANS;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IEF;FP7;Rydberg Interactions at Nanostructured Surfaces;2010-07-01;2012-06-30;;The applicant will move from France to the UK to carry out novel experimental studies of the interaction and ionization of laser-excited Rydberg atoms and molecules at a nanostructured metallic surface under UHV conditions. Of primary interest is to understand how the charge transfer process occurring is dependent on the spectroscopically selected quantum states of the Rydberg species, the electronic and geometrical structure of the surface, and on the relative sizes of the nanoparticles and the Rydberg orbital. The experimental work will be backed up with theoretical wavepacket calculations of the Rydberg electron dynamics. The Fellow will transfer his expertise and experience built up in atom-chip, ultracold atom and molecule experiments in Physics laboratories in France and China to the Oxford host research group and its collaborators, while gaining new experience and knowledge of surface science, molecular laser spectroscopy techniques and theory in the Chemistry department at Oxford. The objective is to prepare him for interdisciplinary experimentation in the future, and for an academic career. He will be enrolled on the Preparation for Academic Practice course at Oxford in support of his objective to obtain an academic career.;179603,2;179603,2;FP7-PEOPLE-2009-IEF;/MC-IEF;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;UK;;;"/SCI;/EDU;/ITT";1;0;0;1;0;0 92816;236296;IFLOW;ONG;FP7-PEOPLE;FP7-PEOPLE-IEF-2008;FP7;Intake Flow Simulation and Optimisation for Hydropower;2009-06-01;2011-05-31;;"The flow simulation and optimization in terms of the efficient water power utilization is the essential topic of the proposal. The main goals of the submitted project are: - To identify the negative influence of ill-designed intake structures at run-off river power plants on the water turbine efficiency and the rotor vibrations; - To find and prove the methodology of intake structure geometry optimization by means of the numerical flow simulation and the physical modelling, and to reach the best conditions for maximal turbine efficiency and its output. The project combines civil hydraulic engineering with mechanical hydraulic engineering. Turbine producers focus on the design of a runner and adjacent water passage, whereas civil engineers concentrate on a broader area of free surface. The project is going to solve the complex intake flow interdisciplinary concerning the entire intake section configuration. The fellow will thus utilize his recent expertise in both fields and to help bridging the existing gap between both civil and mechanical engineering. Undertaking of the project will also enable the fellow to acquire the better familiarity with CFD simulation methods and their implementation into hydropower and to deepen many other complementary skills. The excellent computation accessories of the host organization will be used for flow simulations. The computed results will be verified on a physical test model in the Hydraulic laboratory at the host institution too. Modern disturbance-free laser anemometry will be applied for measurements at physical model. Regarding the support of power renewable resources, the resolved problems are very current nowadays. There are lots of refurbishments of outdated low head run-off river power plants in order to increase higher efficiency of hydropower generation. That’s why it is important to deal with a question, to what extent the ill-shaped intake structures influence the turbine behaviour.";;168717,32;FP7-PEOPLE-IEF-2008;/MC-IEF;TECHNISCHE UNIVERSITAET DRESDEN;DE;;;"/SCI;/EMP";1;0;0;1;0;0 101760;290336;MetTrans;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-ITN;FP7;Metal Transport in the Environment;2012-02-01;2016-07-31;;Understanding the processes that control the transport of metals in the environment is essential for a wide range of fields, including environmental protection and remediation, mineral resources, climate change. Through recent analytical developments, it is possible, using natural variations in metal isotopes, to identify and quantify how metal concentrations in natural waters are controlled by interactions with mineral surfaces, microbially-mediated reactions, and release during mineral weathering, and so significantly advancing our understanding of the fate and consequences of metal transport in the environment However, such applications have not been extensively exploited. The proposed MetTrans scientific and training Network will address a range of critical societal and industrial applications. This includes the abiotic and microbial immobilization of contaminants, the role of metals in carbon sequestration, and the response of metal transport to climate change. This requires interdisciplinary input, from chemistry, geology, physics, biology, hydrology, and engineering, and the solution to many of these problems requires close academic-industrial collaboration – academia will provide the scientific expertise and state-of-the-art analytical techniques to the practical applications confronted by industry. Although the particular research questions considered are diverse, the underlying scientific principles and analytical techniques are similar. This therefore provides an excellent platform to train young scientists in using of isotopic methods, understanding metal behaviour, and utilizing skills broadly. The Network focuses on providing training on analytical skills, on understanding fundamental principles, and on modelling, and exposes young scientists to a wide range of opportunities for applying this training in research and industry.;3584452;3584452;FP7-PEOPLE-2011-ITN;/MC-ITN;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;UK;"LULEA TEKNISKA UNIVERSITET;NATURHISTORISKA RIKSMUSEET;UNIVERSITY OF DURHAM;ALS SCANDINAVIA AB;AMPHOS 21 CONSULTING SL;UNIVERSITAT AUTONOMA DE BARCELONA;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;LANDSVIRKJUN SAMEIGNARFELAG;SVENSK KARNBRANSLEHANTERING AKTIEBOLAG";"SE;UK;ES;FR;IS";"/LIF;/SCI";1;0;0;1;0;0 101498;268268;CIPTT;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-RG;FP7;ESTABLISHMENT OF A CENTER FOR INTELLECTUAL PROPERTY AND TECHNOLOGY TRANSFER (CIPTT) IN THE FORMER YUGOSLAV REPUBLIC OF MACEDONIA;2011-12-01;2016-07-02;;"'The purpose of the requested Marie Curie IRG is to assist Dr. Bratislav Stankovic in his permanent professional reintegration into his native country, the Former Yugoslav Republic of Macedonia (FYROM). Dr. Stankovic has spent 19 years in the USA as a researcher, scholar, educator, and law practitioner, acquiring professional experience in both the academic and private sectors. He recently accepted employment as a full-time faculty member at the University American College (UACS) in Skopje. The award of an IRG should assist Dr. Stankovic to share in his native country his knowledge and expertise in intellectual property (IP) rights, technology transfer (TT), science, and socio-economic development. He has already developed expertise and track record in IP law, technology and knowledge transfer, both as a scholar and as a law practitioner, working for one of the largest IP law firms in the USA. He is keenly aware of the global developments in IP law and TT. An award of an IRG would be instrumental in supporting his efforts to create an interdisciplinary Center (CIPTT) intended to promote a strategic focus on innovation in, and development of, various industries - and to enhance commercialization of research. The long-term goal of this effort relates to promotion and enablement of innovation, intellectual asset management, fostering the creation of new technologies, tools, SMEs, and paradigms in the FYROM. The CIPTT will have a strong intersectoral aspect, bringing together experts from diverse areas such as law, economics, science, business, and education, thus combining a unique set of partner skills. The establishment of the Center will be an incremental yet important step in the positioning of FYROM as a place of smart, sustainable and inclusive growth built upon an economy in which knowledge and innovation are the primary tools, where development stems from brains rather than brawn or materials (in line with EC’s 'Europe 2020: a new economic strategy').'";100000;100000;FP7-PEOPLE-2010-RG;/MC-IRG;REPUBLIC OF MACEDONIA - UNIVERSITY FOR INFORMATION SCIENCE AND TECHNOLOGY ST.PAUL THE APOSTLE OHRID;MK;PRIVATE HIGHER EDUCATION INSTITUTION - UNIVERSITY AMERICAN COLLEGE SKOPJE PRIVATNA USTANOVA;MK;/SCI;1;0;0;1;0;0 108497;600411;BREMEN TRAC;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-COFUND;FP7;COFUND Fellowships for Transnational Academic Careers;2013-02-01;2018-01-31;;"'The ‘BREMEN TRAC – COFUND Fellowships for TRansnational Academic Careers’ programme will enable incoming researchers to conduct an independent research project in a highly competitive and vibrant research landscape. With no thematic restrictions, research topics and hosting institutes at the University of Bremen can be freely chosen. BREMEN TRAC explicitly targets excellent researchers residing outside Germany and offers two-year fellowships with a standard salary and an additional research allowance to early stage postdocs. In addition, international TRAC fellows coming to Bremen will avail themselves of a broad range of support measures testifying to Bremens reputation as a talent incubator. BREMEN TRAC can capitalize on experiences with our own long-established and highly competitive postdoctoral programme: Selection committees and judgement criteria based on merit are already in place and administrative procedures will be easily adapted. External peer review already is a crucial element in the selection of the fellows. The existing programme has considerably been extended in scope two years ago. However, it has always been geared towards national applicants. BREMEN TRAC will offer nearly as much additional positions, but explictly to international researchers. This will contribute to fostering transnational mobility of highly promising researchers in the ERA at an early career stage. TRAC Fellows will greatly benefit from being integrated in a dense interdisciplinary research network with the University of Bremen at its center, offering stimulating research to connect to. Furthermore the university campus offers them ample opportunities for engaging in research cooperations with non-university institutes of excellence, e.g. including institutes of the Max Planck Society (MPG) or the Fraunhofer Society (FhG). The university’s close cooperation with the region’s private sector provides the chance to engage in R&D activities'";2982978;1193191,2;FP7-PEOPLE-2012-COFUND;/MC-COFUND;UNIVERSITAET BREMEN;DE;;;/LIF;1;0;0;1;0;0 191388;631149;TNBChemiRNet;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-CIG;FP7;Enhancing chemotherapy response in triple negative breast cancer (TNBC) by modulating miRNA-target network and identifying biomarkers of response;2014-07-01;2018-06-30;;Triple-negative breast cancer (TNBC) is the most aggressive type of breast cancer and therapies are primarily limited to conventional chemotherapy. TNBC patients who respond to neo-adjuvant chemotherapy with a pathological complete response (pCR) have excellent 5-year survival (up to 94%). However, this represents the minority of TNBC patients (25-40%). The remaining patients have less than 60% 5-year survival due to aggressive relapse. Therefore, increasing the pCR rate of chemotherapy in TNBC holds great promise for improving survival. Furthermore, it is important to identify biomarkers to predict/stratify TNBC patients with higher probability of response to chemotherapy. Recently, microRNAs (miRNAs), which are 20-22 nucleotide small RNAs, emerged as master regulators of several oncogenic processes including therapy resistance and have great potential to be used as therapeutics due to their ability to repress several oncogenic proteins simultaneously. Moreover, miRNAs have also been shown to be promising biomarkers for diagnosis, prognosis and therapy response in cancer. Herein I propose to study the potential for modulation of miRNAs/their target networks to enhance the response to chemotherapy and to identify biomarker of chemotherapy response in TNBC. In this line, I will develop in vivo chemoresistant models using both xenografts and tumor transplants from an established TNBC mouse model. Combining whole genome miRNA/mRNA sequencing, bioinformatics and network biology, miRNAs/their target network involved in chemoresistance will be identified, and targeted to enhance the chemoresponse of TNBC models. Finally, the biomarker potential of identified miRNAs/targets in TNBC patient tumors will be tested with inter-(national) collaborations from two different countries. Overall, this interdisciplinary study will provide pre-clinical data to enhance chemotherapy response in TNBC and identify biomarkers stratifying patients with higher response rate to chemotherapy.;100000;100000;FP7-PEOPLE-2013-CIG;/MC-CIG;BILKENT UNIVERSITESI VAKIF;TR;;;/LIF;1;0;0;1;0;0 187830;624170;SEAQUEST;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IEF;FP7;Meso and Sub-mesoscale Physico-biogeochemical Dynamics in a Coastal NW Mediterranean Sea: Quantifying and Understanding Ecosystem Structure and Transport;2015-04-01;2017-03-31;;"Shelf and coastal regions are at the interface between continents (impacted by human activities) and the open ocean (the main regulator of our planet’s climate and its biogeochemical cycles). The shelf-sea carbon pump largely relies on lateral transport to remove atmospheric CO2 from the ventilated surface waters and sequester it at depth. A good understanding of the physical transport processes in coastal regions and their impact on the ecosystem dynamics is therefore not only important for future climate predictions but also has a more immediate relevance (e.g., knowledge of local transport is necessary for the creation of marine protected areas, the management of spills, or the mitigation of harmful blooms events, etc.). SeaQUEST will study the horizontal transport and cross-shelf exchange processes including their effect on the biogeochemistry in the coastal zone around the Gulf of Lion (GoL) off the French Mediterranea coast, a highly productive area and important feeding ground for fish, birds, and mammals, both resident and migratory. The main goal of SeaQUEST is to examine the role of the Northern Current as a physical barrier to cross-shelf transport and the effect of its seasonal variability on the local biogeochemistry and plankton dynamics at meso- and sub-mesoscales. This will be achieved through a highly interdisciplinary approach employing a range of methods and data (numerical simulations, in situ and satellite observations). SeaQUEST will provide new insights into the ecosystem functioning and biological-physical interactions in a highly productive and economically important coastal area which is also one of the main tourist destinations worldwide. The results will therefore be of broad relevance to a variety of stakeholders including decision makers and local managers.";269743,8;269743,8;FP7-PEOPLE-2013-IEF;/MC-IEF;UNIVERSITE D'AIX MARSEILLE;FR;;;;1;0;0;1;0;0 185952;623673;Reproduction;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IOF;FP7;Historicizing Reproduction;2015-03-01;2018-02-28;;"The aim of this project is to historizise the shifts and moves reproduction underwent from a concept that described a pregiven capacity fixed in “life” and defining matter as “living” to a capacity apprehended through technoscience and open to transformation. It focuses on the 20th century as a central period when the “technoscientific turn” in reproduction took place. The project investigates reproduction as a dispersed phenomenon in time and space that transgresses bodies, disciplines, the boundaries of nature and society, a phenomenon which cannot be understood as an isolated problem of medicine and biology. Instead it resituates reproduction in a knot of multiple and surprising genealogies and as a multi-sited process which needs to be tackled by a constellation of methodological tools to do justice to its complexity. To historicize reproduction means not only to ask how genealogical and heteronormative arrangements of reproduction have been undone, rearranged, and even queered but also to investigate reproductive practices from a broad, interdisciplinary framework, such as history, anthropology, and science and technology studies (STS). This project’s historicization of reproduction will follow along the three main axis of transindividuality, temporalities and economy, themes that are pivotal to charting reproduction as a relational process . The project will foreground theses axis by focusing on three domains of reproductive sciences and their entanglements: reproductive medicine, agriculture and livestock breeding, and those fields that explore aggregate forms of life - collectives, societies, populations – like public health, the global health movement, and international feminism with a specific emphasis on non-western countries like South-Asia and Latin-America.";252244,8;252244,8;FP7-PEOPLE-2013-IOF;/MC-IOF;UNIVERSITAET BREMEN;DE;;;/LIF;1;0;0;1;0;0 186826;631186;NanoOrder;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-CIG;FP7;Nanoscale Organisation and Dynamics of Ionic Networks at Biological Interfaces;2014-06-01;2018-05-31;;In solution, ions tend to accumulate near charged surfaces and form an electrostatic double layer. The ionic density of the double layer is generally well understood, but little is known about the lateral organization of the ions at the surface. The existence of ordered ionic networks could have dramatic consequences for interfacial processes, for example in charges and molecules transfer. In biology and soft matter, ions networks would also affect the mechanical properties of interfaces and could help re-shape the cell. Recent developments in the field of atomic force microscopy have made it possible to image single ions on surfaces and study the formation of organized networks over tens of nanometres with molecular precision. NanoOrder investigates the formation of such structures at model bio-interfaces, in solution. The aim of this interdisciplinary project is to unravel the mechanisms that allow soft bio-membranes to control complex ionic networks through their molecular organization and physical properties.;100000;100000;FP7-PEOPLE-2013-CIG;/MC-CIG;UNIVERSITY OF DURHAM;UK;;;/LIF;1;0;0;1;0;0 104338;312184;PHARMASEA;ONG;FP7-KBBE;KBBE.2012.3.2-01;FP7;Increasing Value and Flow in the Marine Biodiscovery Pipeline;2012-10-01;2017-03-31;;The PharmaSea project focuses on obstacles in marine biodiscovery research, development and commercialization and brings together a broad interdisciplinary team of academic and industry researchers and specialists to address and overcome these. The partners are ideally placed to demonstrate how to widen the bottlenecks and increase the flow of ideas and products derived from the marine microbiome towards a greater number of successes in a larger number of application areas. Despite the tremendous potential of marine biodiscovery, exploitation, particularly at a commercial scale, has been hampered by a number of constraints. These relate to access (physical and legal), genetics of the organisms, compound isolation, structure elucidation, early reliable validation of biological activity and best mechanisms of flow-through into exploitation. PharmaSea will solve these chronic bottlenecks by developing essential actions beyond the state of the art and linking them with best practice and appropriate pragmatic approaches. The robust pipeline structure established within PharmaSea will process a wide genetic basis including marine microbial strain collections held by partners and new strain collections from extreme environments (deep, cold and hot vent habitats) to produce new products with desirable characteristics for development by the SME partners in three accessible market sectors, health (infection, inflammation, CNS diseases), personal care and nutrition. The global aim of PharmaSea is to produce two compounds at larger scale and advance them to pre-clinical evaluation. To address relevant challenges in marine biodiscovery related to policy and legal issues, PharmaSea will bring together practitioners, legal experts, policy advisors/makers and other stakeholders, focusing on the feasibility of harmonising, aligning and complementing current legal frameworks with recommendations and ready to use solutions tailored to marine biodiscovery.;13194699,8;9465907;FP7-KBBE-2012-6-singlestage;/CP-TP;KATHOLIEKE UNIVERSITEIT LEUVEN;BE;"UNIVERSITETET I TROMSOE;THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN;DEEP TEK LIMITED;THE ROYAL SOCIETY OF CHEMISTRY;ADVANCED CHEMISTRY DEVELOPMENT UK LIMITED;SEALIFE PHARMA GMBH;ASOCIACION INSTITUTO NACIONAL DE BIODIVERSIDAD;STAZIONE ZOOLOGICA ANTON DOHRN;BIOCOM;C-LECTA GMBH;UNIVERSIDAD DE SANTIAGO DE COMPOSTELA;UNION INTERNATIONALE POUR LA CONSERVATION DE LA NATURE ET DE SES RESSOURCES;WUHAN UNIVERSITY;UNIVERSITY OF THE WESTERN CAPE;CONSIGLIO NAZIONALE DELLE RICERCHE;AQUAPHARM BIODISCOVERY LIMITED;DANMARKS TEKNISKE UNIVERSITET;FUNDACION CENTRO DE EXCELENCIA EN INVESTIGACION DE MEDICAMENTOS INNOVADORES EN ANDALUCIA;ECOAST;UNIVERSITY OF WAIKATO;Instituto de Dinamica Celular y Biotecnologia;UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK;BIOBRIDGE LIMITED;Institute of Microbiology, Chinese Academy of Sciences";"NO;UK;AT;CR;IT;DE;ES;CH;CN;ZA;DK;BE;NZ;CL;IE";/SCI;1;0;0;1;0;0 110996;337128;AAREA;ONG;FP7-IDEAS-ERC;ERC-SG-SH6;FP7;The Archaeology of Agricultural Resilience in Eastern Africa;2014-02-01;2018-01-31;;"'The twin concepts of sustainability and conservation that are so pivotal within current debates regarding economic development and biodiversity protection both contain an inherent temporal dimension, since both refer to the need to balance short-term gains with long-term resource maintenance. Proponents of resilience theory and of development based on ‘indigenous knowledge’ have thus argued for the necessity of including archaeological, historical and palaeoenvironmental components within development project design. Indeed, some have argued that archaeology should lead these interdisciplinary projects on the grounds that it provides the necessary time depth and bridges the social and natural sciences. The project proposed here accepts this logic and endorses this renewed contemporary relevance of archaeological research. However, it also needs to be admitted that moving beyond critiques of the misuse of historical data presents significant hurdles. When presenting results outside the discipline, for example, archaeological projects tend to downplay the poor archaeological visibility of certain agricultural practices, and computer models designed to test sustainability struggle to adequately account for local cultural preferences. This field will therefore not progress unless there is a frank appraisal of archaeology’s strengths and weaknesses. This project will provide this assessment by employing a range of established and groundbreaking archaeological and modelling techniques to examine the development of two east Africa agricultural systems: one at the abandoned site of Engaruka in Tanzania, commonly seen as an example of resource mismanagement and ecological collapse; and another at the current agricultural landscape in Konso, Ethiopia, described by the UN FAO as one of a select few African “lessons from the past”. The project thus aims to assess the sustainability of these systems, but will also assess the role archaeology can play in such debates worldwide.'";1196701;1196701;ERC-2013-StG;/ERC-SG;UNIVERSITY OF YORK;UK;UNIVERSITY OF DURHAM;UK;"/SCI;/SOC";1;0;0;1;0;0 110139;602012;UNISEC;ONG;FP7-HEALTH;HEALTH.2013.2.3.0-1;FP7;Universal Influenza Vaccines Secured;2013-10-01;2018-03-31;;"UNISEC brings together a European consortium of 3 University partners, 5 National Health Institutes and 3 SMEs, all with leading expertise in influenza vaccine research and development, to work on promising recently developed concepts for a universal influenza vaccine. The consortium is exceptionally strong, interdisciplinary and intersectional in nature, and encompasses a unique combination of scientific and technological expertise from lead identification to clinical trial execution. UNISEC will bring a number of vaccine concepts together into a single study in order to identify, develop and clinically test the 3 most promising leads for a universal influenza vaccine, which must (1) demonstrate adequate (universal) protection, and (2) be technically suitable for development to a marketable product. Preclinical and clinical methodologies will be developed allowing a comparative evaluation of the vaccine concepts. Head-to-head comparisons in animal models will also be performed, with the most promising concepts to then be ready for clinical assessment. Independent comparative clinical studies will be executed and carried out by 5 established Clinical Trial Site partners. The expected impact of the UNISEC work programme will be the resolution of current problems of non-uniformity in the development and evaluation of universal influenza vaccines in Europe by a unified approach using an expert and sustainable vaccine expertise network. The UNISEC results will directly contribute to a timely, longer-term, broader, more effective and cost-effective universal influenza vaccine for the prevention of annual and pandemic influenza. The success of UNISEC will be based on the leading experience of its consortium partners; the proven track record of its clinical trial site partners; and a coherent and well-defined management structure and dissemination program, underpinned by the fact that several UNISEC partners were previously part of the successful EU FLUSECURE project.";7824984,91;5972180,5;FP7-HEALTH-2013-INNOVATION-1;/CP-FP;RIJKSUNIVERSITEIT GRONINGEN;NL;"FOLKEHELSEINSTITUTTET;Medicines and Healthcare products Regulatory Agency;ROBERT KOCH-INSTITUT;STATENS SERUM INSTITUT;ACADEMISCH ZIEKENHUIS GRONINGEN;Department of Health england;BIONDVAX PHARMACEUTICALS LTD;NOVAVAX AB;GOETEBORGS UNIVERSITET;RETROSCREEN VIROLOGY LTD;PEPTCELL LTD;ORSZAGOS EPIDEMIOLOGIAI KOZPONT";"NO;UK;DE;DK;NL;IL;SE;HU";/LIF;1;0;0;1;0;0 102474;294947;SWAN;ONG;FP7-INCO;INCO.2011-7.6;FP7;Sustainable Water ActioN: building research links between EU and US;2012-03-01;2016-02-29;http://swanproject.arizona.edu/;"The project promises to strengthen European research capacity in the USA, promote competitiveness of European research and industry while informing and involving policy-makers and the general public. Opening the UMI to European partners responds to the need for 21st Century interdisciplinary and multiregional collaboration regarding water sustainability. We have exhausted the 20th century paradigm of technocratic or institutional solutions and are compelled to apply multi-faceted approaches that combine physical, natural, and social sciences, along with governance perspectives. This extension of the UMI broadens its current activities from a bi-national focus to one that incorporates ideas, disciplines and methods from Europe. By connecting the UMI with Europe, scientific cooperation will enhance ongoing activities, bring new projects, establish a foundation for future collaboration in the framwork of a EU/USA Sustainable Water Centre (SWC). A Feasibility Study will fully explore how the UMI will achieve this major institutional step. To optimise the cooperation among partners, three major transverse themes will structure the work plan: Climate change and uncertainty, Risks and vulnerabilities and Participation. Work Packages are: 1)Water resources sustainability, 2) EU/USA issues in water governance, 3) Water demand and sustainability, 4) Urban water: EU/USA common models 5) Feasibility Study, 6) Management Strategy; 7) Dissemination/communication.";2356551;1999202;FP7-INCO-2011-7;/CSA-SA;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FR;"Arizona Board of Regents;UNITED NATIONS EDUCATIONAL, SCIENTIFIC AND CULTURAL ORGANIZATION -UNESCO;UNIVERSITY OF THE WEST OF ENGLAND, BRISTOL;NATIONAL INSTITUTE OF GEOPHYSICS GEODESY AND GEOGRAPHY - BULGARIAN ACADEMY OF SCIENCES;UNIVERSIDAD DE SEVILLA";"US;FR;UK;BG;ES";/REG;1;0;0;1;0;0 108563;306587;COMUNEM;ONG;FP7-IDEAS-ERC;ERC-SG-PE8;FP7;Computational Multiscale Neuron Mechanics;2013-05-01;2018-04-30;;'The last few years have seen a growing interest for computational cell mechanics. This field encompasses different scales ranging from individual monomers, cytoskeleton constituents, up to the full cell. Its focus, fueled by the development of interdisciplinary collaborative efforts between engineering, computer science and biology, until recently relatively isolated, has allowed for important breakthroughs in biomedicine, bioengineering or even neurology. However, the natural “knowledge barrier” between fields often leads to the use of one numerical tool for one bioengineering application with a limited understanding of either the tool or the field of application itself. Few groups, to date, have the knowledge and expertise to properly avoid both pits. Within the computational mechanics realm, new methods aim at bridging scale and modeling techniques ranging from density functional theory up to continuum modeling on very large scale parallel supercomputers. To the best of the knowledge of the author, a thorough and comprehensive research campaign aiming at bridging scales from proteins to the cell level while including its interaction with its surrounding media/stimulus is yet to be done. Among all cells, neurons are at the heart of tremendous medical challenges (TBI, Alzheimer, etc.). In nearly all of these challenges, the intrinsic coupling between mechanical and chemical mechanisms in neuron is of drastic relevance. I thus propose here the development of a neuron model constituted of length-scale dedicated numerical techniques, adequately bridged together. As an illustration of its usability, the model will be used for two specific applications: neurite growth and electrical-chemical-mechanical coupling in neurons. This multiscale computational framework will ultimately be made available to the bio- medical community to enhance their knowledge on neuron deformation, growth, electrosignaling and thus, Alzheimer’s disease, cancer or TBI.';1128960;1128960;ERC-2012-StG_20111012;/ERC-SG;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;UK;;;"/PSE;/EAR";1;0;0;1;0;0 92120;239481;PETALEVODEVO;ONG;FP7-PEOPLE;PEOPLE-2007-4-3.IRG;FP7;Resurrection of Developmental Pathways in the Evolution of the Petal;2009-10-01;2012-09-30;;Our project concerns the evolution of petal conical cells in a group of flowering plants, the Caryophyllales. The fellow has determined that following a loss of petals in the Caryophyllales, petals have subsequently re-evolved 9 times. Conical cells, which perform a vital role in interacting with pollinators, often occur on these re-evolved petals. The host has demonstrated that MIXTA-like R2R3 MYB genes specify conical cells in distant lineages of flowering plants. We hypothesise that recurrent evolution of these conical cells in separate occurrences of re-evolved petals is due to repeated recruitment of the MIXTA-like R2R3 MYB genes. We will test this hypothesis by isolating R2R3 MYB genes from 3 species representing distinct evolutions of the petal in the Caryophyllales. We will conduct phylogenetic analyses to determine if the same or distinct lineages of R2R3 MYB genes have been recruited to specify conical cells. We will assess if the genes are expressed in the conical cells. We will perform a transformation assay into tobacco to determine if the MIXTA-like R2R3 MYB genes are functioning as in other flowering plants. We will analyse the function of the genes in vivo, through RNAi and overexpresssion. The host’s collaborators demonstrated that MIXTA-like R2R3 MYB genes are directly activated by the transcription factors APETALA3 and PITILLATA, to induce conical cells. However, the fellow has shown that APETALA3 and PISTILLATA are often absent from these re-evolved petals. We ask how MIXTA-like R2R3 MYB genes are turned on if APETALA3 and PISTILLATA are absent. We will answer this by analyzing the promoters of the R2R3 MYB genes to identify novel regulatory elements. The fellow’s expertise on Caryophyllales petal evolution, combined with the host’s expertise on MIXTA-like R2R3 MYB genes enables an interdisciplinary approach. It is an important study for the emerging field of evolutionary developmental biology, and will enhance scientific research in the EU.;75000;75000;FP7-PEOPLE-IRG-2008;/MC-IRG;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;UK;;;"/SCI;/COO";1;0;0;1;0;0 108474;311460;DrugE3CRLs;ONG;FP7-IDEAS-ERC;ERC-SG-LS7;FP7;"Probing Druggability of Multisubunit Complexes: E3 Cullin RING Ligases";2013-05-01;2018-04-30;;This proposal is centred on the development and application of chemical tools to probe molecular recognition of multiprotein complexes. Although much effort has been devoted to targeting protein-protein interactions using small molecules, these have focused to date on individual gene products or truncated domains, which however do not reflect the physiological organization and activity of many functional proteins. Few successes have been achieved, yet many of the key physical determinants of druggability of surfaces within native protein complexes have remained elusive. The aim of this project is to shed light upon this problem by chemically interrogating biological systems that rely on several subunits working in concert rather than on single proteins working alone. As model system we will investigate the Cullin RING Ligases (CRLs), the largest superfamily of multisubunit E3 ligases in humans. These enzymatic machines are responsible for the recognition, poly-ubiquitination and targeting of substrate proteins to the proteasome for degradation. Many members of this family have crucial roles in cellular physiology and homeostatis, are implicated in a wide range of diseases and are attractive targets for drug discovery. Two interdependent lines of enquiry will be followed. First, we will screen for and elucidate the binding of small molecular fragments and short peptides to identify new druggable surfaces and interfaces on CRLs and their components. Second, we will exploit the nature of the interactions to develop novel chemical probes of CRLs. As the probes are selected and optimised for binding rather than for a particular functional outcome, diverse mechanisms of action are envisaged beyond conventional disruption of the interaction. The successes of this interdisciplinary research will provide a step change in how we interrogate protein-protein interactions of functional and pathological pathways with impact in many areas of chemical biology and drug discovery.;1499904;1499904;ERC-2012-StG_20111109;/ERC-SG;UNIVERSITY OF DUNDEE;UK;;;"/BIO;/LIF";1;0;0;1;0;0 108613;600407;BANDIERA;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-COFUND;FP7;Best Action for National Development of International Expert Researchers Activity;2013-03-01;2017-02-28;;"The BANDIERA (“Best Action for National Development of International Expert Researchers Activities”) COFUND Programme proposed by CNR is based on two national Flagship Projects (Progetti Bandiera), pluri-annual large national projects launched within the National Plan for Research 2011-2013, the Government’s formal planning of national priorities and strategies for research. Amongst those coordinated by CNR, the two Flagship Projects involved in this proposal are RITMARE, a national project for marine scientific and technological research and NanoMax, project aimed to establish a network of laboratories and in vitro diagnostic (IVD) companies in the fields of nanoscience and nanotechnology. The projects have officially started in early 2012 and will run for 5 and 3 years respectively. The BANDIERA Programme is aimed to attract incoming experienced researchers from EU Members States, Associated and Third Countries wishing to undertake interdisciplinary research and training in the fields covered by the Flagship Projects, in order to contribute to the further development and strengthening of their career prospects and also to facilitate cooperation with their institutions and countries of origin. The context of the proposed programme will offer fellows the opportunity to carry out research projects of their choice by means of individual personalised projects, in state of the art research facilities and to enhance their scientific and technical skills through a broad selection of training modules integrated with complementary skills development. In total 13 positions are envisaged (6 for RITMARE and 7 for NanoMax) for a duration of 24 months each. The fellows will be recruited by CNR to ensure homogeneous employment contracts and conditions, and will be hosted either at CNR Institutes or at any other institution participating in the 2 Flagship Projects, on the basis of specific agreements that will be stipulated on purpose, according to their research projects.";2016907,2;806762,88;FP7-PEOPLE-2012-COFUND;/MC-COFUND;CONSIGLIO NAZIONALE DELLE RICERCHE;IT;;;/LIF;1;0;0;1;0;0 107853;321381;ProNet;ONG;FP7-IDEAS-ERC;ERC-AG-LS9;FP7;ProNet - Prosthetic Transgene Networks for the Treatment of Metabolic Disorders;2013-05-01;2018-04-30;;Since living memory, the basic treatment strategies for the therapy of human diseases has not much changed conceptually. Although the molecular understanding of metabolic disorders continues to progress significantly the therapeutic strategy is still based on specific, often heterologous compounds which interfere with critical disease targets, trigger a metabolic bypass reaction or complement a molecular deficiency. As systems biology is revealing gene-function correlations and metabolic network dynamics at great pace and synthetic biology enables bottom-up de-novo design of genetic devices with predictable behaviour, time has now come to develop novel treatment strategies. Prosthetic genetic networks are expected to play a central part of such future treatment strategies. Prosthetic networks are synthetic sensor/effector devices or molecular prostheses which, upon integration into cells and functional connection to their metabolism, monitor disease-relevant metabolites, process off-level concentrations and coordinate adjusted diagnostic, preventive or therapeutic responses in a seamless, automatic and self-sufficient manner. Using a synthetic biology approach and capitalizing on our pioneering prosthetic network designed to control urate homeostasis and treat the tumour lysis syndrome as well as gouty arthritis, ProNet is a highly integrated, multiparallel and interdisciplinary effort to provide a series of prosthetic sensor/effector circuits for precise trigger-control of therapeutic transgenes. ProNet will focus on providing novel treatment opportunities for diabetes and obesity, two core pathologies of the metabolic syndrome, which is on its way to become the top epidemic of the 21st century. ProNet may provide new opportunities for the treatment strategies of the future thereby making the classic therapy of taking pills and getting injections in specified amounts and at particular times likely to become a thing of the past.;2498800;2498800;ERC-2012-ADG_20120314;/ERC-AG;EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH;CH;;;"/ABI;/BIO;/LIF;/MED;/MBI";1;0;0;1;0;0 102908;303713;ENIGMA;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-CIG;FP7;Engineering Network and Interference Geometry for the Analysis and Design of Next Generation Wireless Networks;2012-04-01;2016-03-31;;"Today, our society, industry and service sectors are increasingly becoming more dependent on information and communication technologies (ICT) in general and wireless telecommunication networks in particular. For example, fourth generation (4G) wireless networks has transformed mobile handsets into intelligent terminals for providing an easy anytime-anywhere access to all sorts of information and services in our daily lives such as location tracking, high-definition video streaming, and portfolio monitoring and management. ICT empowered with next generation wireless protocols for machine-to-machine communication is expected to decrease total greenhouse gas emissions from all industry sectors by 15%, and to advance current medical and public health practices significantly within the next decade. Such a wide range of application areas brings together new interoperability challenges for heterogeneous network architectures and requires innovative approaches for interference mitigation to support data rates as high as 1 Gbits/sec in low mobility and 100 Mbits/sec in high mobility environments. This project will engineer network and interference geometry to derive fundamental performance bounds and to mitigate interference for next generation heterogeneous wireless and complex networks. It will combine stochastic geometry and random geometric graphs with the theory of complex networks, nonlinear optimization and advanced distribution approximation techniques to discover hidden dynamics and underlying fundamental properties peculiar to these networks. Novel, distributed, practical and provably optimal or near-optimal algorithms will be devised to manage and control heterogeneous wireless and complex communication networks, as well as safeguarding them against unexpected failures, attacks and anomalies. Project outcomes are also expected to find interdisciplinary applications beyond wireless networks to other complex networks such as Internet and social networks.";100000;100000;FP7-PEOPLE-2011-CIG;/MC-CIG;ULUSLARARASI ANTALYA UNIVERSITESI;TR;;;/SCI;1;0;0;1;0;0 106632;308370;CLEANSEA;ONG;FP7-ENVIRONMENT;ENV.2012.6.2-4;FP7;Towards a Clean, Litter-Free European Marine Environment through Scientific Evidence, Innovative Tools and Good Governance;2013-01-01;2015-12-31;http://www.cleansea-project.eu;There is an urgent need for an improved knowledge base for the management of marine litter. CLEANSEA aims to generate new information on the impacts (biological, social and economic) of marine litter, develop novel tools needed to collect and monitor litter and protocols needed for monitoring data (litter composition and quantities) and evaluate the impact of mitigation strategies and measures in order to provide options to policy makers in the EU. This will be achieved through 7 work packages. WPs 2 and 3 cover biological impacts and technical aspects of marine monitoring, monitoring tools and applications. WP4 investigates multilevel socio-economic impact and barriers to Good Environmental Status, providing a justification for the development of management measures and policy options in WP5. This WP combines advanced institutional analysis with a participatory approach in order to identify and assess management measures, strategies and policy options in collaboration with stakeholders that reduce marine litter and alleviate diverse ecological and socio-economic impacts as identified in WPs 2-4. WP6 will integrate the outcomes of the project and hosts the CLEANSEA Stakeholder Platform. Management is dealt with under WP1 with a professional dissemination package, including a documentary film, website, publications, etc. covered in WP7. CLEANSEA includes top scientific groups from eleven European countries distributed over all marine regions. It also includes six SMEs, four of them focused on technological innovation of monitoring, mitigation and recycling tools. CLEANSEA will tackle the marine litter problem from a broad interdisciplinary perspective . Advancement is expected in the array of monitoring tools and systems, knowledge about impacts, and management measures and policy options. By searching for new paradigms and integrating knowledge and methods, CLEANSEA intends to contribute concrete elements to the road map towards strong reductions in marine litter.;3788527,71;2986570,99;FP7-ENV-2012-two-stage;/CP;STICHTING VU;NL;"INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE MARINA GRIGORE ANTIPA;CORPUS DATA MINING HANDELSBOLAG;THE UNIVERSITY OF EXETER;denkstatt Bulgaria OOD;CENTRO MEDITERRANEO DE ESTUDIOS PARA EL USO Y CONSERVACION DE LAS COSTAS;HELLENIC CENTRE FOR MARINE RESEARCH;NORSK INSTITUTT FOR LUFTFORSKNING STIFTELSE;EIGEN VERMOGEN VAN HET INSTITUUT VOOR LANDBOUW EN VISSERIJONDERZOEK;CALLISTO PRODUCTIONS LTD;KC DENMARK AS;STICHTING DELTARES;OREBRO UNIVERSITY;WOLTHUIS YVONNE BARBARA;PANEPISTIMIO AIGAIOU;CORPUS DATA & IMAGE ANALYSIS AB;ECOLOGIC INSTITUT gemeinnützige GmbH;KIMO NEDERLAND EN BELGIE";"RO;SE;UK;BG;ES;EL;NO;BE;DK;NL;DE";/SCI;1;0;0;1;0;0 103184;303685;GLOBEF;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-CIG;FP7;The impacts of global environmental change for marine biotic interactions and ecosystem functioning;2012-04-01;2017-01-18;;Oceans cover 70% of our planet, provide 90% by volume of its biosphere, support 50% of global primary production and provide vital ecosystem services, including climate regulation, carbon sequestration and the provision of protein, on which large proportions of the global population rely. The Earth’s oceans are, however, increasingly subject to multiple interacting anthropogenic stressors. At the global scale, ocean acidification and global warming, considered two of the 21st century’s grand challenges, potentially pose the greatest threat to ecosystems and the goods and services they provide. However, regional scale stressors, such as eutrophication and over-fishing, are interacting with these global scale stressors, leading to non-linear ecosystem responses. To date, there is little understanding of the combined impacts of these stressors on marine organisms or the processes that structure marine ecosystems. The proposed research seeks to directly address this knowledge gap by undertaking a series of novel, integrated, robust manipulative experiments, at a hierarchy of spatial (local to global) and temporal scales (short to medium term), to determine the combined impacts of multiple climate (global warming and ocean acidification) and non-climate (eutrophication) stressors on marine biodiversity, community interactions and ecosystem functioning. Outcomes from this research will provide the first quantitative evidence of how multiple, interacting global environmental change stressors will affect the strength and direction of biotic interactions, ecosystem functioning and through interdisciplinary collaborations, changes to food-web dynamics and the economic sustainability of our oceans. Without a multi-species, ecosystem-level understanding of marine biological responses to global environmental change, adaptive management policies that are so vitally needed to ensure the sustained use of the Earth’s marine resources, will not be fit-for-purpos;100000;100000;FP7-PEOPLE-2011-CIG;/MC-CIG;ABERYSTWYTH UNIVERSITY;UK;;;/SCI;1;0;0;1;0;0 106939;323404;Muslond;ONG;FP7-IDEAS-ERC;ERC-AG-SH5;FP7;Music in London, 1800-1851;2013-05-01;2018-04-30;;"This project aims to construct a wide-ranging interdisciplinary history of music in London in the first half of the nineteenth century. It will be original in method and scope, will generate a series of book-length publications, and is intended to serve as a model for a new kind of music historiography. Past histories of Western music-making have mostly focussed on elite culture, and have tended to write about music in relative isolation from the other arts and humanities. Our project will take as its focus musical activity in a period and a city which, for both material and aesthetic reasons, offers excellent opportunities for exploring a broader and more inclusive kind of history. Music-making in London functioned as a widely-based industry, providing much professional employment and featuring in the education of many an amateur; it also contributed to private and public enjoyment, became a source of boredom and occasional irritation, and fostered the creation of a host of cultural, political and imagined communities. A history that takes seriously all these functions could enable twenty-first-century scholars from many fields to understand better music’s affective presence in nineteenth-century society. It could also, by considering in detail an unprecedentedly wide range of genres and activities, find fresh relevance for musicology alongside work in other disciplines.";1977800;1977800;ERC-2012-ADG_20120411;/ERC-AG;KING'S COLLEGE LONDON;UK;;;/SOC;1;0;0;1;0;0 103803;303534;BIOWEB;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-CIG;FP7;Towards an Ecosystem-based Approach of Marine Resources: Linking BIOodiversity, Food WEBs, Ecosystem Services and Drivers;2012-06-01;2016-05-31;;Marine ecosystems have been and are subjected to various anthropogenic and environmental disturbances since historic times, which are cumulative and sometimes can act synergistically, additively or antagonistically. These are human activities such as fishing, pollution, eutrophication, invasion of species and the climate change, and changes due to environmental drivers related to changes in oceanographic dynamics, temperature, salinity and ultimately primary productivity. These ecosystem dynamics represent a scientific challenge although little is known about cumulative effects, and even less about their combined impacts. The objective of my research entitled “Towards an Ecosystem-based Approach of Marine Resources: Linking BIOodiversity, Food WEBs, Ecosystem Services and Drivers” (BIOWEB) is to quantify how the structure and functioning of marine food webs changes under these human and environmental cumulative and combined disturbances, and develop an understanding of how the changes in diversity and abundance of marine organism impact ecosystem functioning, and ultimately the services that marine ecosystems provide to humans (such as provisioning, regulating, supporting and cultural services) and to ecosystem health. In BIOWEB I will analyse the cumulative effects of different anthropogenic drivers together, and to include in the analysis the environmental factors in addition to anthropogenic disturbances. Until now, anthropogenic impacts have been assessed individually and environmental impacts tend to be included separately in the analysis. This will allow to progress towards a more complex and realistic analysis under the global change context, and evaluate the impact of human and environmental impacts on marine ecosystems. To accomplish my objective I will use an interdisciplinary approach combining meta-analysis of historical and recent biological data, with advanced ecosystem modelling, and laboratory experiments using microcosms.;100000;100000;FP7-PEOPLE-2011-CIG;/MC-CIG;INSTITUT DE RECHERCHE POUR LE DEVELOPPEMENT;FR;AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS;ES;/SCI;1;0;0;1;0;0 110354;607332;QuantFung;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-ITN;FP7;Quantitative Biology for Fungal Secondary Metabolite Producers;2013-10-01;2017-09-30;http://intern.mikrobiologie.tu-berlin.de/;"QuantFung represents the first European training platform for the production of novel bioactive compounds based on fungal synthetic biology. The ITN will train 11 early-stage (ESR) and 4 experienced researchers (ER) as new problem-solving, creative European scientists in interdisciplinary and intersectorial biotechnological research ranging from modelling, network analysis, systems biology (genomics, transcriptomics, proteomics and metabolomics), and molecular biology (fungal genetics and biochemistry) to synthetic biology methods. To bridge the gap between science education and industry, industrial partners provide secondments and training modules to share their industry experience with the trainees. The driving force is a collaboration of 8 academic and 5 industrial partners to expedite the application of new secondary metabolites in health, nutrition or agriculture. The objective is to find novel bioactive molecules by exploiting the wealth of fungal biodiversity and to translate these into useful products. Work packages structure training through research focussed on discovery of secondary metabolite gene clusters, targeted activation of gene clusters, quantification of secondary metabolites in industrial hosts, and bioactivity testing to identify their mode of action. These multidisciplinary projects require physical and intellectual mobility and are organised as a structured training program where ESRs/ERs work for defined periods in different QuantFung laboratories and attend local and network training events to broaden their technical knowledge and acquire transferable skills to optimize career options. 46 secondments representing 19 new collaborations between the public and private sector will lead to new avenues of research. The broad spectrum of expertises of QuantFung covers numerous cross sector elements leading to researchers with significant translational and entrepreneurial skills to strengthen European research.";3859189,53;3859189,53;FP7-PEOPLE-2013-ITN;/MC-ITN;TECHNISCHE UNIVERSITAT BERLIN;DE;"DSM FOOD SPECIALTIES BV;DEBRECENI EGYETEM;GEORG-AUGUST-UNIVERSITAT GOTTINGENSTIFTUNG OFFENTLICHEN RECHTS;CHRISTIAN-ALBRECHTS-UNIVERSITAET ZU KIEL;LEIBNIZ-INSTITUT FUR NATURSTOFF-FORSCHUNG UND INFEKTIONSBIOLOGIE EV HANS-KNOLL-ISTITUT;DANMARKS TEKNISKE UNIVERSITET;RIJKSUNIVERSITEIT GRONINGEN;CHALMERS TEKNISKA HOEGSKOLA AB";"NL;HU;DE;DK;SE";/LIF;1;0;0;1;0;0 105576;306277;SMART;ONG;FP7-IDEAS-ERC;ERC-SG-PE7;FP7;Shapeable Magnetoelectronics in Research and Technology;2013-01-01;2017-12-31;http://www.smartsensorics.eu/;"In our everyday life we are surrounded by sensing devices designed in a way to meet requirements of a certain application, which is determined primarily by their shape and size. What I propose here is to break this old vision in sensor engineering and to develop shapeable magnetoelectronics allowing to reshape sensors upon demand after fabrication. These devices are unique as the same initial sensor can be used for multiple purposes: an elastic magnetic sensor integrated in a fluidic tubing can be applied for therapeutic needs; namely, diagnostics of cancer diseases by examining magnetically tagged living cells. Alternatively the same sensor can be mounted on a curved surface of a stator in a tiny gap between rotor and stator in electrical machines to provide a regulation for the rotor position; these sensors can help to reduce energy consumption of electrical machines. European added value / Sustainability: My group is the first which produced shapeable magnetic sensors and pointed out industrial applications of this technology. Supporting this initiative gives advantage to the EU in development of a unique class of devices with important functionality being not only flexible and fast, but also with the ability to react and respond to a magnetic field. There are no alternatives for this technology; therefore as a long term perspective this project will provide a leading position to the EU in the field of shapeable (magnetic) sensorics. The project is in line with main initiatives of the EU: (i) reduction of energy consumption and (ii) development of novel concepts for disease diagnostics. The European principles of gender diversity management will be obeyed. To accomplish the goals of the project, I need to expand my team by 1 Postdoc and 3 PhDs working on this interdisciplinary project combining physics, engineering, fluidics, and biology. The grant requested is 1499.76 kEUR. The department of research funding (IFW Dresden) will support me to manage the project.";1499760;1499760;ERC-2012-StG_20111012;/ERC-SG;HELMHOLTZ-ZENTRUM DRESDEN-ROSSENDORF EV;DE;LEIBNIZ-INSTITUT FUER FESTKOERPER- UND WERKSTOFFFORSCHUNG DRESDEN E.V.;DE;"/PSE;/AER;/SPA";1;0;0;1;0;0 94754;252173;NABIO;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IEF;FP7;New bioactive agents based on natural products;2010-06-01;2012-05-31;;"More than 1 in 3 people in the EU will develop cancer during their lifetime. Despite huge investment, insufficient new bioactive molecules are emerging, and there is urgent need for a different approach to research in this area. Drawing inspiration from Nature, the Fellow will investigate natural products with anticancer potential. The objective of the IEF is to support the career development of a talented researcher, to improve and develop her skills in preparation for an independent scientific career. The research objectives are to exploit the medicinal activity in naturally occurring quinones in an interdisciplinary programme involving chemical synthesis of the natural compounds and analogues, and their biological evaluation, maximizing the synergy between the Fellow and the Host Laboratory. The objectives will be measured against: • development of innovative chemical routes to bioactive quinones, including natural products and analogues; • biological evaluation of novel compounds as potential therapeutic agents; • publication of high quality papers; • establishment of research collaborations between UK and Italian groups. The project brings together complementary scientific communities in research aimed at developing novel therapeutic agents, particularly for cancer. The substantial training element will be of huge benefit to the Fellow in establishing her independent academic career by complementing and reinforcing her medicinal chemistry background with synthetic organic chemistry.";173240,8;173240,8;FP7-PEOPLE-2009-IEF;/MC-IEF;THE UNIVERSITY OF NOTTINGHAM;UK;;;"/SCI;/EDU;/ITT";1;0;0;1;0;0 110702;612619;EUINDEPTH;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IRSES;FP7;European Identity, Cultural Diversity and Political Change;2014-01-01;2017-12-31;;"The strategic objective of the whole FP7 is to support research in all areas, including the Science in Society. The major goal of the Seventh Framework Programme for research and Technological Development is to keep the EU as a world leader. The European identity, cultural diversity and political changes could be the key issue in the encouragement of societal dialog on research policy, stimulating all players to be more active in research, promoting shared values among EU countries and the third countries. The proposed research project brings together 8 European universities and research centres from France, Germany, United Kingdom, Portugal, Italy, Belguim, Poland, Hungary ( EU MS coutries), Moldova (AC) and 7 participant institutions from Russian Federation (third country). It builds on existing cooperation in frame of international networks and associations of European Studies and will enhance the already active collaboration in the fields of European identity and cultural diversity. The establishment of this staff exchange program will in addition promote and strengthen the complementarity of the participants involved and will boost collaborative research activities. The primary objective of this international and interdisciplinary group of research team is to form an excellent center of synergy in research and knowledge transfer in the area of European studies. It is supposed to establish long lasting collaborations through exchange of people and realization of different activities, including meetings and workshops. The main aim of the proposal is to contribute to mutual understanding between nations, development of intercultural communications, identification of similarities and differences of views from European and Russian, Ukrainian sides and search for overcoming of contradictions on the issue of perception of what Europe is, its geographical and cultural borders, what people in project partner countries put into the words “being a European”.";735300;735300;FP7-PEOPLE-2013-IRSES;/MC-IRSES;INSTITUTUL DE ECONOMIE, FINANTE SI STATISTICA;MD;"UNIVERSITA' DEGLI STUDI DI SIENA;GEORG-AUGUST-UNIVERSITAT GOTTINGENSTIFTUNG OFFENTLICHEN RECHTS;THE UNIVERSITY OF BIRMINGHAM;UNIVERSIDADE DE COIMBRA;EOTVOS LORAND TUDOMANYEGYETEM;INSTITUT D'ETUDES POLITIQUES DE BORDEAUX;KATHOLIEKE UNIVERSITEIT LEUVEN";"IT;DE;UK;PT;HU;FR;BE";/LIF;1;0;0;1;0;0 103189;281691;MITOSIGAGE;ONG;FP7-IDEAS-ERC;ERC-SG-ID1;FP7;Mitochondrial crosstalk signalling in the regulation of ageing;2012-06-01;2018-05-31;;Mitochondrial defects are associated with aging and age-related pathology, but the molecular mechanisms regulating mitochondrial function during ageing are poorly understood. The most relevant genetic pathway regulating ageing is the insulin/IGF-1 signalling (IIS) pathway. The mitochondrial prohibitin (PHB) complex influences cellular metabolism and mitochondrial biogenesis, affecting ageing in opposite ways in wild-type animals and IIS-defective C. elegans mutants. The aim of the proposed research programme is to shed light on the intricate communication between mitochondria and cell-signalling networks in the regulation of ageing. Our specific objectives are: 1-Elucidate the cellular signalling pathways involved in the metabolic responses to mitochondrial dysfunction upon PHB depletion in wild type animals and IIS-defective mutants, using genome-wide RNAi screens, 2-Conduct a comprehensive metabolic profiling of wild type and IIS mutants in the presence and absence of prohibitins and 3-Identify genetic suppressors of prohibitins by performing forward genetic suppressor screens. As an ultimate goal, genes discovered in C. elegans will be tested in vertebrate assays for a conserved role in ageing. We will implement an interdisciplinary approach that combines the genetic power of C. elegans with state-of-the-art metabolomic approaches as well as automated sorting and optical imaging technologies to monitor fat content and mitochondrial biogenesis, in a genome-wide scale, in vivo. The fine-tuning of cellular metabolism, by integration of diverse signalling inputs is the molecular basis of longevity. This project represents a truly integrative and innovative approach to identify cellular signalling pathways involved in mediating lifespan-extending metabolism adjustments, and what these metabolic adjustments entail. These studies will provide fundamental insights to understand the ageing process and to combat ageing-related diseases.;1424640;1424640;ERC-2011-StG_20101109;/ERC-SG;UNIVERSIDAD PABLO DE OLAVIDE;ES;;;/SCI;1;0;0;1;0;0 108059;323035;Anti-Virome;ONG;FP7-IDEAS-ERC;ERC-AG-LS6;FP7;A combined evolutionary and proteomics approach to the discovery, induction and application of antiviral immunity factors;2013-04-01;2018-03-31;;'Humans are equipped with a variety of intrinsic immunity or host restriction factors. These evolved under positive selection pressure for diversification and represent a first line of defence against invading viruses. Unfortunately, however, many pathogens have evolved effective antagonists against our defences. For example, the capability of HIV-1 to counteract human restriction factors that interfere with reverse transcription, uncoating and virion release has been a prerequisite for the global spread of AIDS. We are just beginning to understand the diversity and induction of antiretroviral factors and how pandemic HIV-1 group M (major) strains evolved to counteract all of them. Here, I propose to use a genetics, proteomics and evolutionary approach to discover and define as-yet-unknown antiviral effectors and their inducers. To identify novel antiviral factors, we will examine the capability of all primate genes that are under strong positive selection pressure to inhibit HIV and its simian (SIV) precursors. This examination from the evolutionary perspective of the invading pathogen will also reveal which adaptations allowed HIV-1 to cause the AIDS pandemic. Furthermore, complex peptide-protein libraries representing essentially the entire human peptidome, will be utilized to identify novel specific inducers of antiviral restriction factors. My ultimate aim is to unravel the network of inducers and effectors of antiviral immunity - the 'Anti-Virome' - and to use this knowledge to develop novel effective preventive and therapeutic approaches based on the induction of combinations of antiviral factors targeting different steps of the viral life cycle. The results of this innovative and interdisciplinary program will provide fundamental new insights into intrinsic immunity and may offer alternatives to conventional vaccine and therapeutic approaches because most restriction factors have broad antiviral activity and are thus effective against various pathogens.';1915200;1915200;ERC-2012-ADG_20120314;/ERC-AG;UNIVERSITAET ULM;DE;;;"/BIO;/LIF";1;0;0;1;0;0 108816;321124;Tailor Graphene;ONG;FP7-IDEAS-ERC;ERC-AG-PE8;FP7;Tailoring Graphene to Withstand Large Deformations;2013-06-01;2018-05-31;;This proposal aims via a comprehensive and interdisciplinary programme of research to determine the full response of monolayer (atomic thickness) graphene to extreme axial tensional deformation up to failure and to measure directly its tensile strength, stiffness, strain-to-failure and, most importantly, the effect of orthogonal buckling to its overall tensile properties. Already our recent results have shown that graphene buckling of any form can be suppressed by embedding the flakes into polymer matrices. We have indeed quantified this effect for any flake geometry and have produced master curves relating geometrical aspects to compression strain-to-failure. In the proposed work, we will make good use of this finding by altering the geometry of the flakes and thus design graphene strips (micro-ribbons) of specific dimensions which when embedded to polymer matrices can be stretched to large deformation and even failure without simultaneous buckling in the other direction. This is indeed the only route possible for the exploitation of the potential of graphene as an efficient reinforcement in composites. Since orthogonal buckling during stretching is expected to alter- among other things- the Dirac spectrum and consequently the electronic properties of graphene, we intend to use the technique of Raman spectroscopy to produce stress/ strain maps in two dimensions in order to quantify fully this effect from the mechanical standpoint. Finally, another option for ironing out the wrinkles is to apply a simultaneous thermal field during tensile loading. This will give rise to a biaxial stretching of graphene which presents another interesting field of study particularly for already envisaged applications of graphene in flexible displays and coatings.;2025600;2025600;ERC-2012-ADG_20120216;/ERC-AG;FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS;EL;;;"/PSE;/MAT;/IND;/CON";1;0;0;1;0;0 106435;307596;OTEGS;ONG;FP7-IDEAS-ERC;ERC-SG-PE3;FP7;Organic Thermoelectric Generators;2013-04-01;2018-03-31;;"At the moment, there is no viable technology to produce electricity from natural heat sources (T<200°C) and from 50% of the waste heat (electricity production, industries, buildings and transports) stored in large volume of warm fluids (T<200°C). To extract heat from large volumes of fluids, the thermoelectric generators would need to cover large areas in new designed heat exchangers. To develop into a viable technology platform, thermoelectric devices must be fabricated on large areas via low-cost processes. But no thermoelectric material exists for this purpose. Recently, the applicant has discovered that the low-cost conducting polymer poly(ethylene dioxythiophene) possesses a figure-of-merit ZT=0.25 at room temperature. Conducting polymers can be processed from solution, they are flexible and possess an intrinsic low thermal conductivity. This combination of unique properties motivate further investigations to reveal the true potential of organic materials for thermoelectric applications: this is the essence of this project. My goal is to organize an interdisciplinary team of researchers focused on the characterization, understanding, design and fabrication of p- and n-doped organic-based thermoelectric materials; and the demonstration of those materials in organic thermoelectric generators (OTEGs). Firstly, we will create the first generation of efficient organic thermoelectric materials with ZT> 0.8 at room temperature: (i) by optimizing not only the power factor but also the thermal conductivity; (ii) by demonstrating that a large power factor is obtained in inorganic-organic nanocomposites. Secondly, we will optimize thermoelectrochemical cells by considering various types of electrolytes. The research activities proposed are at the cutting edge in material sciences and involve chemical synthesis, interface studies, thermal physics, electrical, electrochemical and structural characterization, device physics. The project is held at Linköping University holding a world leading research in polymer electronics.";1453689,6;1453689,6;ERC-2012-StG_20111012;/ERC-SG;LINKOPINGS UNIVERSITET;SE;;;"/PSE;/ELM;/NNT";1;0;0;1;0;0 108174;321323;NEOGAL;ONG;FP7-IDEAS-ERC;ERC-AG-PE9;FP7;New frOntiers in Galaxy spectrAl modeLing;2013-05-01;2018-04-30;;"'NEOGAL is an intensive, coordinated effort to explore uncharted territory in the early chemical evolution of galaxies through the development of an innovative set of spectral analysis tools. This will be achieved through the accomplishment of four interdisciplinary projects using state-of-the-art techniques: 1. The development of a new approach overcoming the limitations of existing methods, to measure the chemical composition of ionized gas with unknown heavy element abundance ratios in high-redshift galaxies; 2. The combination of this approach with sophisticated models of the ultraviolet emission from young stellar populations, to allow differentiated constraints on the chemical composition of stars and gas; 3. The combination of these models with cosmological simulations of galaxy formation, to identify the spectral signatures of competing scenarios of early chemical evolution in observations of statistical samples of high-redshift galaxies; 4. The development of an integrated web service to allow the astronomical community at large to exploit these models to interpret observations of distant galaxies. The spectral analysis tools developed in the framework of this project will open powerful new opportunities to probe the early star formation and chemical enrichment histories of galaxies. Moreover, by allowing the consistent interpretation of stellar and nebular emission, these tools will provide valuable constraints on parameters such as the escape fraction of ionizing photons and hence the contribution by galaxies to the ionizing background. These models therefore should have a profound impact on the optimal design of future surveys of primeval galaxies that will be carried out with the next generation of large facilities, such as the James Webb Space Telescope and the European Extremely Large Telescope.'";2400555,6;2400555,6;ERC-2012-ADG_20120216;/ERC-AG;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FR;;;"/PSE;/AER;/SPA";1;0;0;1;0;0 107401;313454;NEUROCOOPERATION;ONG;FP7-IDEAS-ERC;ERC-SG-SH4;FP7;Trust & Reciprocity: neural and psychological models of social cooperation;2013-03-01;2018-02-28;;Novel interdisciplinary approaches offer an exciting avenue to study interactive decision-making by combining the methods of behavioral experiments, functional neuroimaging, and formal economic models. This project employs this approach to explore decision-making related to trust, reciprocity, cooperation and fairness in social interactive scenarios. These processes are vital for the successful functioning of society, but there have been relatively few studies of the mechanisms involved. This proposal will examine in detail the psychological and neural mechanisms behind these processes. Project 1 will investigate how we place trust in others, by using behavioral, neuroimaging, and computational modeling. The aims are to explore the influence of both automatically processed cues as well as the cognitive processes of learning from experience. Project 2 will investigate how we reciprocate trust, in particular the role of positive and negative emotions in this decision. The aim is to construct detailed, neurally-inspired models of this process, and test competing theories of reciprocation. Project 3 will explore the factors underlying cooperation between individuals and groups, particularly with relevance to the roles of reward, punishment and agency. Finally, Project 4 will investigate how our expectations of the world shape our responses to social situations. Social norms can have a large impact on our decisions, and we will build models that incorporate expectations and explore their neural correlates. Overall, this project can greatly enhance our knowledge of decision-making in social interactive contexts, with both theoretical and practical relevance. The innovative approach has the potential to advance our knowledge of existing theoretical accounts by constraining models based on the underlying neurobiology, and the knowledge gleaned can have a real impact on questions of public policy.;1451927;1451927;ERC-2012-StG_20111124;/ERC-SG;STICHTING KATHOLIEKE UNIVERSITEIT;NL;;;/SOC;1;0;0;1;0;0 190983;913876;HDIMSM;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IIF;FP7;Self-Assembled Virus-Like Particles from Polyferrocenylsilane-Based Polymers and Viral Capsid Proteins: Fabrication, Surface Engineering and Applications;2017-02-01;2018-01-31;;The capsid proteins of viruses have been shown to organize around a variety of non-biological polyanions, in a similar way that proteins assemble around RNA genomes, to form virus-like particles (VLPs). Metal-containing polymers such as polyferrocenylsilane possess additional interesting physical and chemical properties and may yield VLPs possessing very different morphologies and more diverse functionalities on co-assembly with capsid proteins. In a similar manner to almost all nanoscale objects, VLPs generally exist in the solid state but not in the liquid phase, because the scales of these systems are typically larger than the range of attractive interactions between such nanostructures. This situation comes with limitations regarding both storage and product formulation. Due to the recent development of liquid proteins via the surface engineering techniques, interest in the phase behavior of bionanomaterials has grown rapidly. The proposed research focuses on the fabrication and surface engineering of responsive VLPs through the self-assembly of polyferrocenylsilane-based copolymers and viral capsid proteins. This project is highly interdisciplinary and the project objectives will be accomplished by the proposed award of a Marie Curie Fellowship to a highly talented young scientist from China, Dr. Hongjing Dou. She has considerable expertise in the area of bionanomaterials and in biomedical science. The proposal involves her working at the School of Chemistry at the University of Bristol in the UK together with Prof. Ian Manners, who has expertise in the field of synthetic metallopolymers such as polyferrocenylsilanes and also self-assembly, and cosupervisor Prof. Stephen Mann, an expert in bio-inspired chemically-derived routes to complex materials and a pioneer of solvent-free liquid proteins and viruses, to achieve the ambitious project goals.;15000;15000;FP7-PEOPLE-2013-IIF;/MC-IIFR;SHANGHAI JIAO TONG UNIVERSITY;CN;;;/LIF;1;0;0;1;0;0 186925;631792;INMA;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-CIG;FP7;Immune and Neuromodulation Mediated by Alphaherpesviruses;2014-04-01;2018-03-31;;"Despite the advances against infectious diseases, morbidity and mortality still pose a very high social and economic impact. Viruses have developed a plethora of strategies to modulate the host. The main goal of my research is to investigate these strategies in order to understand viral immunomodulation, neuromodulation and pathogenesis. This will permit us to develop better intervention approaches to combat viral infections and their role in neuropathies. Due to their high prevalence and adaptation to their hosts, I will focus on relevant human pathogens within the Herpesviridae family: herpes simplex virus type 1 and type 2 (HSV-1 and HSV-2, respectively) and varicella zoster virus (VZV). These viruses establish latency in sensory ganglia of the peripheral nervous system. The mechanisms that allow the colonization of the nervous system by these viruses are unknown. The interplay between the virus and the immune system is relevant for persistence and pathogenesis. Chemokines and neurotrophic factors play a relevant role in the crosstalk between the immune and nervous systems. We have recently discovered the first mechanism employed by a virus, HSV, to modulate both sets of proteins. This novel strategy may be relevant for HSV spread, colonization of the nervous system and pathogenesis. Other relevant human pathogens, such as VZV, may express modulators of chemokines and/or neurotrophic factors. These hypotheses will be addressed using molecular, cell biology, functional assays, and mouse models. My previous experience in viral modulation, the multidisciplinary approach of the project and the interdisciplinary environment of the host institution will ensure the feasibility of this proposal. We will discover novel viral mechanisms of immune, neuromodulation and pathogenesis providing relevant insights on the cellular processes involved. The results will permit developing better intervention approaches to combat viral infections and their role in neuropathies.";100000;100000;FP7-PEOPLE-2013-CIG;/MC-CIG;MEDIZINISCHE HOCHSCHULE HANNOVER;DE;;;/LIF;1;0;0;1;0;0 105954;313668;ACROSSBORDERS;ONG;FP7-IDEAS-ERC;ERC-SG-SH6;FP7;Across ancient borders and cultures: An Egyptian microcosm in Sudan during the 2nd millennium BC;2012-12-01;2018-04-30;;"Pharaonic Egypt is commonly known for its pyramids and tomb treasures. The present knowledge of Egyptian everyday life and social structures derives mostly from mortuary records associated with the upper classes, whereas traces of ordinary life from domestic sites are generally disregarded. Settlement archaeology in Egypt and Nubia (Ancient North Sudan) is still in its infancy; it is timely to strenghten this field. Responsible for the pottery at three major settlement sites (Abydos and Elephantine in Egypt; Sai Island in Sudan), the PI is in a unique position to co-ordinate a research project on settlement patterns in Northeast Africa of the 2nd millennium BC based on the detailed analysis of material remains. The selected case studies situated across ancient and modern borders and of diverse environmental and cultural preconditions, show very similar archaeological remains. Up to now, no attempt has been made to explain this situation in detail. The focus of the project is the well-preserved, only partially explored site of Sai Island, seemingly an Egyptian microcosm in New Kingdom Upper Nubia. Little time is left to conduct the requisite large-scale archaeology as Sai is endangered by the planned high dam of Dal. With the application of microarchaeology we will introduce an approach that is new in Egyptian settlement archaeology. Our interdisciplinary research will result in novel insights into (a) multifaceted lives on Sai at a micro-spatial level and (b) domestic life in 2nd millennium BC Egypt and Nubia from a macroscopic view. The present understanding of the political situation in Upper Nubia during the New Kingdom as based on written records will be significantly enlarged by the envisaged approach. Furthermore, in reconstructing Sai Island as “home away from home”, the project presents a showcase study of what we can learn about acculturation and adaptation from ancient cultures, in this case from the coexistence of Egyptians and Nubians";1497460;1497460;ERC-2012-StG_20111124;/ERC-SG;LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN;DE;OESTERREICHISCHE AKADEMIE DER WISSENSCHAFTEN;AT;"/SCI;/SOC";1;0;0;1;0;0 109957;607686;VAMPIRE;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-ITN;FP7;Vascular antibody-mediated pharmaceutically induced tumour resection;2013-09-01;2017-08-31;;'The most significant advance in cancer therapeutics in recent years has been the introduction of monoclonal antibodies into widespread clinical usage. A consequence of this rapid emergence of antibodies as therapeutics is a lack of trained scientists within the EU with the requisite skills to enable antibody development at a globally competitive pace. The University of Birmingham (UoB) together with the SME SomantiX (SOM) aims to address this need by training the next generation of scientists with the appropriate skills. Together with seven associated partners, we have created an intersectorial EID proposal titled “Vascular-Antibody Mediated Pharmaceutically Induced tumour REsection” or VAMPIRE. The primary aim of the proposal is to train 5 early stage researchers while conducting an internationally competitive oncology research project. VAMPIRE will provide training across a wide range of disciplines involved in the production of antibodies and in their evaluation as therapeutics in animal models of cancer. Training will be provided through an integrated partnership involving all of the partners in the consortium ensuring interdisciplinary and intersectoral experience for the ESRs. The antibodies that we aim to develop will target markers of the tumour vasculature that we have identified previously, including CLEC14A. The commercial partner SOM is a Dutch SME specialized in the development of tumour vascular targeting agents. The findings of this project will be of interest to cancer research and the wider public community. Intellectual property generated by the project is envisioned to be licensed to SOM. Pre-clinical development of the antibodies is envisioned to be carried out via strategic alliances with academic partners and other small biotechnology companies. We view pharmaceutical companies as future business and product development partners in clinical phases of antibody testing.';1467958,8;1467958,8;FP7-PEOPLE-2013-ITN;/MC-ITN;THE UNIVERSITY OF BIRMINGHAM;UK;SOMANTIX BV;NL;/LIF;1;0;0;1;0;0 109877;607022;REGPOL?;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-ITN;FP7;Socio-economic and Political Responses to Regional Polarisation in Central and Eastern Europe;2014-01-01;2017-12-31;;The ITN RegPol? - Socio-economic and Political Responses to Regional Polarisation in Central and Eastern Europe centers on new patterns of regional disparities between metropolised core regions and the remaining parts of Central and Eastern European countries (CEE). Such spatial patterns have become a striking feature of the current settlement system of these countries and have lately fuelled concerns about further polarisation and the peripheralisation of non-metropolitan regions. Patterns of regional polarisation, however, do not remain restricted to CEE, but can be found throughout the European Union, albeit at different degrees. As such, there is an EU-wide high demand for professionals able to deal with the spatial implications of these issues. This holds true all the more so as balancing spatial development has been a major goal of European Regional Policy. Against this background, RegPol? trains 16 young researchers for careers in academia, public administration, NGOs and the private sector. Research training is organised in 3 work packages which comprise individual, albeit strongly interconnected research projects. Each project includes intersectoral secondments providing trainees with occupational skills while at the same time strengthening the interface between academia and the private sector. Local trainings will be supplemented by network-wide events enabling strong collaboration between the partners. Training includes transferable skills as well as theoretical and methodological units. The network draws on expertise from academia and private sector specialists from 7 different countries and 8 scientific disciplines used to working in interdisciplinary and multi-national contexts. Next to new training capacities at European level and an increased employability of ITN fellows, the project aims at improving regional policy instruments by raising capacities of politicians, public and private sector policy makers related to issues of regional polarisation.;3165808,58;3165808,58;FP7-PEOPLE-2013-ITN;/MC-ITN;LEIBNIZ-INSTITUT FUR LANDERKUNDE EV;DE;"SLOVENSKA TECHNICKA UNIVERZITA V BRATISLAVE;TARTU ULIKOOL;UNIVERSITATEA BABES BOLYAI;SOCIAL IMPACT GGMBH;MEPCO, SRO;MAGYAR TUDOMANYOS AKADEMIA KOZGAZDASAG- ES REGIONALIS TUDOMANYI KUTATOKOZPONT;OSAUHING GEOMEDIA";"SK;EE;RO;DE;CZ;HU";/LIF;1;0;0;1;0;0 106362;320694;Probiotiqus;ONG;FP7-IDEAS-ERC;ERC-AG-PE2;FP7;Processing of biomolecular targets for interferometric quantum experiments;2013-04-01;2018-03-31;;"Recent studies in Vienna have shown that surprising quantum phenomena, such as matter-wave interferometry with molecules composed of hundreds of covalently bound atoms, are actually feasible. PROBIOTIQUS will now be the first project world-wide to develop experimental tools for matter-wave physics with large biomolecules from amino acid clusters up to proteins and self-replicating molecules. First, we shall exploit the full potential of coherent molecule metrology for biomolecules, and molecules in a biomimetic environment. This research connects quantum physics with chemistry and biophysics, since already a restricted number of precisely determined geometrical, electrical, magnetic or optical properties may provide tell-tale analytical information. Embedding the biomolecules in a hydrate layer will allow us to study their properties in a context that approaches the ‘natural’ environment. Second, we will develop molecular beam methods, optical manipulation tools and detection schemes to prepare proteins and other large biomolecules for advanced quantum experiments. This includes new laser-assisted acoustic and thermal volatilization methods, slowing and focusing in optical forces, diffraction at ionization and neutralization gratings as well as tagging of proteins with ionizable small biomolecules. Third, we will prepare a cryogenic biomolecular sample in a buffer-gas loaded ion trap, where optical ionization and neutralization will be optimized in order to enable optical diffraction gratings. The target temperature of 10 K will be the starting point for interference experiments with proteins and self-replicating RNA, on the way towards full viruses. Quantum interference with large biomolecules at the edge to life has remained an outstanding challenge throughout the last two decades. The ERC advanced grant will now focus on this goal with novel and interdisciplinary strategies, in world-wide unique experiments.";2266904;2266904;ERC-2012-ADG_20120216;/ERC-AG;UNIVERSITAT WIEN;AT;;;"/PSE;/SCI";1;0;0;1;0;0 107009;322586;V-RNA;ONG;FP7-IDEAS-ERC;ERC-AG-LS1;FP7;Two facets of viral RNA: mechanistic studies of transcription and replication by influenza-like viral polymerases and detection by the innate immune system;2013-05-01;2018-04-30;;RNA viruses infect cells to replicate and repackage their genomes in progeny virions. In response, the cellular innate immune system detects viral RNA and triggers powerful anti-viral countermeasures. This proposal aims to elucidate atomic resolution molecular mechanisms associated with these conflicting interests, and will address the following questions: firstly, how do RNA polymerases of segmented, negative sense, single-stranded RNA viruses such as influenza and bunyaviruses transcribe and replicate viral RNA and secondly, how do RIG-I like helicases, intracellular, innate immune, pattern recognition receptors, selectively detect RNA only of viral origin, thus triggering interferon production and induction of the anti-viral state? A third, more exploratory part of the proposal will use proteomics analysis to identify all host factors that are bound to viral mRNAs in influenza virus infected cells. The interdisciplinary project will combine state-of-the-art structural biology with cell-based functional assays and global analysis. Results will advance fundamental understanding of polymerases and helicases, both complex RNA-dependent molecular machines, give new insight into the regulation of innate immune receptor activation and signalling, and shed new light on RNA metabolism in the perturbed environment of the infected cell. They will also impact virology and public health by bringing new knowledge on RNA virus-host interactions, virus evolution and inter-species transmission. More pragmatically the project will boost structure-based anti-viral drug development targeting serious and/or emerging human pathogens such as influenza A, which poses the perennial threat of a devastating pandemic, and the many disease causing bunyaviruses, which in a globally warming world could spread unpredictably. The V-RNA project thus forms a coherent whole covering important protagonists in the virus-versus-host-versus-virus molecular warfare centered around viral RNA.;2371934;2371934;ERC-2012-ADG_20120314;/ERC-AG;EUROPEAN MOLECULAR BIOLOGY LABORATORY;DE;;;"/BIO;/LIF";1;0;0;1;0;0 107016;324246;EVOLAEMP;ONG;FP7-IDEAS-ERC;ERC-AG-SH4;FP7;Language Evolution: The Empirical Turn;2013-04-01;2018-03-31;;"'This proposal describes a highly interdisciplinary approach to the empirical study of cultural language evolution. It draws on ideas and methods from *historical linguistics and typology*, *natural language processing*, *biology*, *bioinformatics*, *computer science*, and *statistics*. The computer aided study of cultural language evolution has seen a tremendous upturn over the past fifteen years. This comprises both model-driven approaches - studying the consequences of design assumptions regarding language production, comprehension, and learning for their long-term population-wide consequences - and data-driven approaches that employ algorithmic techniques from bioinformatics to recover otherwise inaccessible information about language history. At the current junction, the field faces two challenges: - The specifics of language evolution - which includes parallels with but also key differences to biological evolution - require central attention. - Model-driven and data-driven approaches need to inform each other to achieve explanatory power and to assess the statistical significance of the findings. The project will establish a radically data-oriented framework for the study of language evolution. This includes three aspects: - replacing the off-the-shelf tools from bioinformatics that are currently in use in computational language classification by linguistically informed algorithms, esp.\ *multiple sequence alignment techniques*, - identifying characteristic traits of language evolution via *exploratory data analysis*, guided by the theory of *complex systems* and employing cutting-edge methods from *machine learning* such as *kernel methods* and *causal inference*, and - developing, implementing and testing models of language evolution that correctly predict the *statistical fingerprints of language evolution*, i.e. pay sufficient attention to the domain specific features of language evolution that have no counterpart in biological evolution.'";2003580;2003580;ERC-2012-ADG_20120411;/ERC-AG;EBERHARD KARLS UNIVERSITAET TUEBINGEN;DE;;;/MED;1;0;0;1;0;0 106039;308223;MAtrix;ONG;FP7-IDEAS-ERC;ERC-SG-PE8;FP7;In silico and in vitro Models of Angiogenesis: unravelling the role of the extracellular matrix;2013-04-01;2018-03-31;;"Angiogenesis, the formation of new blood vessels from the existing vasculature, is a process that is fundamental to normal tissue growth, wound repair and disease. The control of angiogenesis is of utmost importance for tissue regenerative therapies as well as cancer treatment, however this remains a challenge. The extracellular matrix (ECM) is a one of the key controlling factors of angiogenesis. The mechanisms through which the ECM exerts its influence are poorly understood. MAtrix will create unprecedented opportunities for unraveling the role of the ECM in angiogenesis. It will do so by creating a highly innovative, multiscale in silico model that provides quantitative, subcellular resolution on cell-matrix interaction, which is key to the understanding of cell migration. In this way, MAtrix goes substantially beyond the state of the art in terms of computational models of angiogenesis. It will integrate mechanisms of ECM-mediated cell migration and relate them to intracellular regulatory mechanisms of angiogenesis. Apart from its innovation in terms of computational modelling, MAtrix’ impact is related to its interdisciplinarity, involving computer simulations and in vitro experiments. This will enable to investigate research hypotheses on the role of the ECM in angiogenesis that are generated by the in silico model. State of the art technologies (fluorescence microscopy, cell and ECM mechanics, biomaterials design) will be applied –in conjunction with the in silico model- to quantity cell-ECM mechanical interaction at a subcellular level and the dynamics of cell migration. In vitro experiments will be performed for a broad range of biomaterials and their characteristics. In this way, MAtrix will deliver a proof-of-concept that an in silico model can help in identifying and prioritising biomaterials characteristics, relevant for angiogenesis. MAtrix’ findings can have a major impact on the development of therapies that want to control the angiogenic response.";1497400;1497400;ERC-2012-StG_20111012;/ERC-SG;KATHOLIEKE UNIVERSITEIT LEUVEN;BE;;;"/PSE;/EAR";1;0;0;1;0;0 98634;273837;See 2 Sense;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-IOF;FP7;Image supramolecular binding processes on the molecular level by STM for fundamental understanding sensor;2011-09-01;2014-11-03;;"The goal of the project is to image supramolecular binding processes on the molecular level with the purpose to gain fundamental understanding of how a sensor operates. This understanding will subsequently be applied as a basis for new sensor design. Scanning Tunneling Microscopy (STM) will be used to visualize single molecule binding events of analyte molecules to receptor molecules adsorbed at a surface. In addition to topography changes, STM will also give valuable information about changes in electronic properties of the receptor upon the binding. This information will be used in the design of new, extremely sensitive sensors based on carbon nanotubes and graphene. The highly interdisciplinary research will be carried out by a promising young European researcher at MIT (USA) under the supervision of Prof. T. M. Swager, and at the Eindhoven University of Technology (the Netherlands) in the group of Prof. R. A. J. Janssen.";234887,2;234887,2;FP7-PEOPLE-2010-IOF;/MC-IOF;TECHNISCHE UNIVERSITEIT EINDHOVEN;NL;;;"/EMP;/SOC;/COO";1;0;0;1;0;0 187874;624794;COMPACTABILITY;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IEF;FP7;Contribution of Compact Neighbourhoods to Social Sustainability;2014-12-01;2016-11-30;;"This research investigates how compact urban form can promote the social sustainability of intermediate neighbourhood areas in the major European cities which face socio-cultural challenges such as social segregation and cultural disintegration. Combining the three critical concepts of ‘neighbourhood development’, ‘compact urban form’, and ‘social sustainability’, the study sheds light on their interconnectivity, and thus provides practical recommendations to promote social sustainability for the neighbourhood level. Despite the fact that these concepts have been incorporated into European urban development policy, a remarkable gap in knowledge is observable: interdisciplinary comparative empirical surveys are needed to investigate their multifaceted aspects and discover the commonalities and differences between different contexts. The two cases of London and Berlin are considered as the case studies, due to the progressive initiatives they have developed with regard to the above-mentioned concepts. Employing a combined methodology including literature review, on-site investigations, interviews, and questionnaires, this research consists of four main stages. After studying the state of the art of the central questions, four neighbourhoods (two each) in intermediate urban areas of the case studies will be selected as field study areas (FSAs). A goal-oriented, multidisciplinary quantitative methodology will measure different indicators of ‘urban form’ and ‘social sustainability’ using progressive tools and indicator-indices (questionnaires). The findings will be scored and evaluated through statistical techniques to explore the interconnectivity of the indicators and their strengths and weaknesses. Ultimately, an Urban Form Enhancement Index will be provided for each FSA which includes recommendations and modifications the adoption of which will further the capacity of the given neighbourhood to serve as an effective structural unit and socially sustainable community.";309235,2;309235,2;FP7-PEOPLE-2013-IEF;/MC-IEF;OXFORD BROOKES UNIVERSITY;UK;;;;1;0;0;1;0;0 187741;623127;H4H;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IEF;FP7;Exploring the therapeutic potential of homoarginine in experimental models of ischemia reperfusion injury and chronic heart failure;2014-04-01;2016-03-31;;"Cardiovascular disease (CVD) remains the leading cause of death within the European Union and new, more effective forms of treatment are urgently needed. Recent studies have shown that patients with low plasma homoarginine are at increased risk of stroke, myocardial infarction and heart failure (HF). This project aims to explore the underlying mechanisms of this association and to determine the therapeutic potential of homoarginine supplementation. We have already shown that mice with homoarginine-deficiency exhibit increased brain injury following an experimental stroke, and further, that elevating homoarginine levels is protective in normal mice. We hypothesize that homoarginine is more a mediator than a mere biomarker for positive outcome in CVD. Specifically, we propose that increased homoarginine in mice will also be beneficial in experimental models of acute ischaemia and chronic HF. Our objectives are, 1) to study whether low homoarginine levels are detrimental in the ischaemic and failing heart and demonstrate rescue by homoarginine treatment; 2) to determine whether homoarginine supplementation is beneficial; and 3) to elucidate the mechanism for how homoarginine exerts its cardiac effects. This interdisciplinary project brings together the applicant’s (Germany) specific expertise in pharmacology and detailed knowledge of the homoarginine research field, with the opportunity to receive extensive in vivo training in an array of cutting-edge murine cardiac phenotyping techniques developed by the scientist in charge (UK). For example, LV catheterization, in vivo MRI, echocardiography, 31P-NMR and surgical models of ischaemia and HF in mice. In conclusion, by extensive training of the Fellow, this project will 1) pave the road to develop scientific independence, 2) foster intra-European collaboration, 3) provide a basis for further funding, and 4) give novel insights into CVD pathophysiology to the scientific community and to the general public.";221606,4;221606,4;FP7-PEOPLE-2013-IEF;/MC-IEF;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;UK;;;;1;0;0;1;0;0 187895;624969;AVATAR;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IEF;FP7;Animated 3D digital reconstructions of early European birds: a new window on the origin of avian flight using “state-of-the-art” techniques on exceptional fossils;2014-09-01;2016-08-31;;'The origin of avian flight is possibly the most spectacular example of an evolutionary transition and, consequently, has aroused passionate scientific debate and fired public attention. The fossil record indicates that birds emerged within theropods (a group of carnivorous dinosaurs that includes species such as Tyrannosaurus rex) in the Late Jurassic. Mesozoic birds are extremely rare. Their fossil remains are mostly known from exceptional sites such as that of Las Hoyas, in Spain. Four beautifully preserved bird specimens (one of them unpublished), representing at least three species, have been found at Las Hoyas. They are intermediate forms between the primeval bird Archaeopteryx and modern birds both in age and evolutionary stage. The recent advances in X-ray imaging technologies and computer modelling, together with the discoveries of these key specimens, make it possible to use digital reconstructions to study the origin and evolution of flight from a biomechanical perspective. This project aims at using various 'state-of-the-art' techniques to re-create digitally these early birds so as to study their preservation, chemistry, locomotion, and flight abilities. The fossil birds from Las Hoyas will be digitally brought back to life thanks to the prodigious possibilities offered by synchrotron imaging (both tomographic and chemical). The 3D musculoskeletal models will be animated according to the limitations dictated by their reconstructed anatomy, so that their flying performance can then be evaluated. The synchrotron-based imaging will also provide data to aid in the reconstruction of plumage patterns of the Las Hoyas birds. This ambitious project will bring together 'state-of-the-art', interdisciplinary science to elucidate and resurrect the biology and locomotor ability of these pivotal avian species.';309235,2;309235,2;FP7-PEOPLE-2013-IEF;/MC-IEF;THE UNIVERSITY OF MANCHESTER;UK;;;;1;0;0;1;0;0 187915;625174;CONSTANTIUS2;CAN;FP7-PEOPLE;FP7-PEOPLE-2013-IEF;FP7;Constantius in Context: Reshaping the Roman Empire;2015-01-01;2016-12-31;;"The reign of the Roman emperor Constantius II (337–361) was instrumental in shaping early models of a united Europe. Constantius presided over religious controversies regarding the definition of Christian orthodoxy and the role of the state in ecclesiastical affairs, and a substantial reorganization of the political, administrative and military aspects of the empire. His reign shaped the state which was to become the Carolingian empire in the west and the Byzantine empire in the east. In the absence of Constantius’ own writings, the literary source tradition for his reign, represented by secular and ecclesiastical writers, is the most complex and hostile towards a single emperor in Roman history. It is characterised by a range of traditional yet developing literary genres which articulate the religious and political anxieties of their age and have obscured Constantius’ role in this formative period of European history. Using theoretical approaches developed within the field of classical literary studies, this project will investigate: (1) how the presentation and reception of Constantius developed in the source tradition between his accession and the mid fifth century; (2) what the shifting critical framework within which these authors judge Constantius tells us about the changing nature and understanding of the imperial office in Late Antiquity; (3) to what extent the literary presentation of Constantius may be reconciled with information derived from laws, inscriptions and numismatic evidence, which illuminate his overhaul of the administrative and legalistic role of the emperor. The outcomes will contribute to several objectives of the ERA and Horizon 2020. Together with creating intra-European collaborations, the scientific outcomes will provide an enhanced interpretation of Constantius’ reign, an enriched understanding of the literary and cultural contextualization of each source author, and a new, interdisciplinary approach to assessing Late Antiquity.";183504,6;183504,6;FP7-PEOPLE-2013-IEF;/MC-IEF;UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN;IE;;;;1;0;0;1;0;0 187817;623995;FORMALBIO;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IEF;FP7;Protein Synthesis Control by Means of Formal Models;2014-10-01;2016-10-15;;"Many biological systems at cellular level consist of a high number of elements interacting in complex patterns. These systems often exhibit emergent behaviours that cannot be detected by reductionist approaches. Systems biology is the interdisciplinary methodology aiming at understanding the dynamics of life by determining how the elements of a biological system interact to form functional networks. This research proposal intends to make to advance the state-of-the-art in systems biology by making systematic use of formal models, and more precisely of the Petri nets formalism. The research will focus on the network of interactions involved in the protein synthesis in Saccharomyces cerevisiae, a species of yeast. The overall goal of the proposal is to optimize the recombinant protein synthesis in this organism. This goal is to be achieved by means of three primary objectives: 1) to formally model the recombinant protein synthesis mechanism; 2) to analyse the obtained model by using formal methods; 3) to control the system behaviour to maximize the recombinant protein synthesis. The Petri net to be designed will model the different events taking place in the protein synthesis mechanism: transcription, translation, modification, transportation, degradation and secretion. The analysis of the Petri net will consider structural and dynamical properties, and special attention will be paid to the computation of throughput bounds and bottleneck identification. As bottlenecks constrain the throughput of the whole system, any control action aiming at maximizing the protein synthesis will be performed on them. Overall, this proposal intends to improve our understanding of the cellular mechanism regulating protein synthesis by providing mathematical modelling and analysis tools. This understanding will eventually enable us to control and optimize the synthesis of recombinant proteins, which are broadly used for vaccines, diagnostic tools and therapeutic purposes.";309235,2;309235,2;FP7-PEOPLE-2013-IEF;/MC-IEF;THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;UK;;;;1;0;0;1;0;0 187738;623098;DryIR;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IEF;FP7;Bloom the Dry. The Creation of Traditional Mediterranean Irrigated Fields;2015-09-01;2017-08-31;;"The main target of the research proposal is to study the historical transformation of Mediterranean drylands into fertile and productive irrigated fields. The construction and maintenance of irrigated fields has been one of the most successful strategies adopted by past societies to cope with the uncertainty of the Mediterranean weather. Many irrigated fields were constructed in the past and are still in use today, being among the most productive agrarian areas in Europe. Irrigated fields have also been considered as a conspicuous feature of Mediterranean arid and semi-arid environments. Several researchers from the natural and the social sciences have studied these agrarian areas. However, most of the research carried out to date has followed a unidisciplinary approach to study fully established irrigated fields. No attention has been paid to their initial formation process, including the nature of the pre-existing dry soils before construction of the fields, the techniques involved in their construction or the edaphological changes brought about by irrigation. My research will tackle these issues through the study of four still-operative, sustainable and highly productive irrigated fields that were constructed for the first time during the Medieval expansion of Islam along the Mediterranean (from AD 632): Saddina (Morocco), and Huerta de Abarán, Horta de Val?ncia and Pla de la Vila (Spain). The integration of geoarchaeological methods with the techniques that will be acquired at the host institution, the Kimmel Center for Archaeological Research, Weizmann Institute of Science, Israel (infrared spectroscopy and phytolith concentration quantification analyses) will allow me to study the genesis of traditional irrigated fields from an interdisciplinary perspective. The proposed research will therefore acquire data of practical use for future european policies aiming at transforming rural Mediterranean drylands into intensive agrarian areas.";184558,8;184558,8;FP7-PEOPLE-2013-IEF;/MC-IEF;UNIVERSITY OF HAIFA;IL;WEIZMANN INSTITUTE OF SCIENCE;IL;;1;0;0;1;0;0 187729;622979;HUBIR;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IEF;FP7;Human-bird interactions from the Roman period to the end of the Middle Ages: Italy and England in their European context;2014-09-01;2016-10-30;;"The political and financial crisis that brought about the collapse of the Roman Empire caused important historical and cultural changes at the Roman-Middle Ages transition. Bird bones recovered from archaeological sites may contribute to our understanding of this important historical process as they are part of the wider material culture of past human societies. They are particularly suited to reflect the complex network of economic, social, religious, political and domestic circumstances and behaviours which characterise past human communities. The project will apply a much needed rigorous scientific approach to the study of bird remains from Italian and British archaeological sites dated to the Roman and Middle Ages periods. Questions such as the development of bird husbandry techniques, the relative importance of different species, their use in ritual activities and the association between birds, social status and environmental changes will be investigated. The research will expand the results of previous work using new zooarchaeological methods (diagnostic zone analysis, observation of butchery marks and biometric analysis), which, in conjunction with the written sources and historical components, will guarantee a holistic approach to the research questions. The project will be particularly innovative in applying such interest to the historical period, to a relative neglected but very important cultural transition (i.e. Roman-medieval) and also by placing its main case studies - Roman and medieval Italy - in their European context. The project will also represent an excellent example of how the barriers between research in humanities and science can be brought down to approach the evidence in a fully interdisciplinary mode. The project will provide evidence that is likely to be of long-lasting effect on research, both in terms of data and approaches, some of which will be entirely new for either or both the study areas.";221606,4;221606,4;FP7-PEOPLE-2013-IEF;/MC-IEF;THE UNIVERSITY OF SHEFFIELD;UK;;;;1;0;0;1;0;0 186921;631774;MagnesiumDIC;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-CIG;FP7;In-Situ Observation and Control of Microstructure and Surface Defect Evolution during Magnesium Sheet Forming;2014-03-01;2018-02-28;;"In recent years, the demand for sheet metal parts of lightweight aluminum and magnesium alloys have considerably increased in the automobile, aviation and mobile electronics sectors. The weight savings offered by these lightweight parts are expected to increase the fuel efficiency in aviation and automotive applications and the mobility of the consumer electronics. However, magnesium and aluminum sheets are more susceptible to defect formation during forming (pressing, stamping, deep drawing, piercing, etc.) operations compared to conventional steels. Microstructure induced defects must be precisely controlled in the automotive and aerospace panels and electronic cases where mechanical properties, physical features and surface quality are very critical. Indeed, innovation in lightweight metals and forming processes are identified as one of the priority areas in the NPM theme of FP7. This project aims to observe the in-situ formation and evolution of the surface defects during magnesium sheet forming through a novel test mechanism involving high-resolution photography and digital image correlation (DIC) techniques. At the end of the project, the mechanisms of the defect formation will be determined and the processing conditions for defect suppression will be established. These results will contribute to the widespread use of lightweight metal sheets in applications where surface properties and quality are critical. Moreover, the testing mechanism developed in this project will have applications in European manufacturing industry and interdisciplinary research, which will help researcher to reintegrate with the European Research Area.";100000;100000;FP7-PEOPLE-2013-CIG;/MC-CIG;MIDDLE EAST TECHNICAL UNIVERSITY;TR;;;/LIF;1;0;0;1;0;0 187865;624646;ACTAGREEN;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IEF;FP7;Aeroelasticity Control for Transportation And GREen ENergy;2014-03-01;2016-02-29;;"The project focuses on two closely related engineering topics of importance to the EU economy and its society. The unrelenting increase in the length of modern suspended-span bridges makes them increasingly vulnerable to wind-induced vibrations and instabilities known respectively as buffeting and flutter (several bridge-construction projects with central span in excess of 1000m are currently being built or planned). In much the same way large wind turbines with power outputs in excess of 10MW and blade length well in excess of 100m are currently being investigated. As the blades of these machines increase in length, while also being constructed from lighter and more flexible materials, they too become susceptible to flutter and buffeting. In the case of large offshore wind farms, which may be exposed to highly unsteady aerodynamic loading, buffet suppression is especially important if this power generation means is to become widespread and economically attractive. The central focus of the proposed work is to seek common techniques for the analysis and suppression of wind-induced oscillations in large flexible civil engineering structures. These apparently unrelated systems face similar challenges and a coordinated attack on both appears to be technically well motivated. The application of small aerodynamics devices will be investigated, in order to devise relatively high frequency and robust control systems, which will be both simulated and tested in wind tunnel. The research is highly interdisciplinary, as it combines mechanics, aerodynamics and control. The main beneficiaries of the work will be the bridge design and construction industry as well as the wind turbine industry. Secondary beneficiaries will include government and society at large, who will have access to cheaper mobility and cheaper wind energy. Additionally the work has important spin-off applications for the fluid-dynamic control of other flexible structures which operate in a turbulent flow field";231283,2;231283,2;FP7-PEOPLE-2013-IEF;/MC-IEF;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;UK;;;;1;0;0;1;0;0 187988;626158;FUNICIS;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IEF;FP7;Functional Ion Conductance and Sensing;2014-06-01;2016-05-31;;This proposal presents unique approaches for the functional characterization of charged interfaces and interfacial phenomena at the nanoscale, through the implementation of an innovative and quantitative ion flux imaging technique. The scientific scope of the project involves the development of a frontier high resolution electrochemical imaging technique, based on scanning ion conductance microscopy that will be capable of probing the nanoscale structure and charge heterogeneity at almost any kind of interface. This represents a major fundamental science aim, that will also open new horizons for the exploration of nanomaterials, including novel electrode materials (graphene and graphene oxide, carbon nanotubes), as well as for imaging self-assembled nanostructures of metallic nanoparticles (NPs). The methodology will allow us to determine the microscopic physicochemical characteristics of individual NPs and their assemblies at soft interfaces and reveal the reactivity of electrocatalytic substrates for fuel cell reactions. We will be able to identify active sites on catalysts and relate these directly to structure - of huge benefit for the understanding and rational design of future functional materials. The research proposal is highly interdisciplinary, and there is a natural fit between the Fellow’s profile and activities at the Host Warwick group. The proposal draws on Fellow’s strong multidisciplinary background in chemistry, mathematical modelling and microtechnology, especially in understanding charged interfaces and nanoscale ion flows, that will be married with the world-leading research on innovative imaging techniques being developed at Warwick. With considerable support and world-leading expertise from the Host group and its collaborators, this project will provide the applicant, Dr. Dmitry Momotenko, with an outstanding opportunity to develop personally and professionally, by pioneering a new area of research in a new geographic location.;221606,4;221606,4;FP7-PEOPLE-2013-IEF;/MC-IEF;THE UNIVERSITY OF WARWICK;UK;;;;1;0;0;1;0;0 187846;624421;WILD ARABIDOPSIS;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IEF;FP7;Pathways, ecological and genomic consequences of genome duplication in Arabidopsis arenosa, an overlooked diploid-polyploid member of the model genus Arabidopsis;2014-09-01;2016-08-31;;The project addresses critical gaps in our understanding of the role of genome duplication (polyploidy) in the genesis and maintenance of plant diversity. While polyploidization is widely acknowledged as a major speciation mechanism in land plants, little is still known about the performance, dynamics, and evolutionary potential of wild polyploid lineages. In my project I propose an interdisciplinary research at the interface between plant systematics, population genetics, and ecological and evolutionary genomics. I will use the novel rapidly developing high throughput sequencing (HTS) techniques which open previously unseen opportunities for studying complex evolutionary processes in plant populations. The potential of such methods in deciphering complex polyploid genomes is, however, still limited mainly due to insufficient knowledge of the genome of the wild plant under study. My project will overcome this gap as it focuses on Arabidopsis arenosa, an overlooked yet extremely promising species that represents the closest wild di-polyploid relative to the key plant model system A. thaliana. I intend to bring and analyze my unique comprehensive set of A arenosa samples (>120 populations) at University of Oslo – a renowned research institution with wide experience in HTS applications and data handling. I aim to examine the overall genetic structure of the species, reveal evolutionary history of the polyploid lineages, and assess the diversity of candidate loci under selection across the species’ range. The project will advance our understanding of evolution and diversity of plant systems, with practical implications in biodiversity conservation, agriculture, and pharmacology. In the course of the project I will significantly improve my skills of leading-edge scientific methods (analyses of high-throughput sequence data) and I will strengthen my position as an independent scientist by getting training in project management and international collaboration.;241066,8;241066,8;FP7-PEOPLE-2013-IEF;/MC-IEF;UNIVERSITETET I OSLO;NO;;;;1;0;0;1;0;0 187896;624974;MED-AFFOREST;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IEF;FP7;Afforestation management in Mediterranean mountain areas: Evaluating the environmental consequences;2014-04-01;2016-03-31;;"Human-induced afforestation has been one of the main policies for environmental management of forest landscapes in Mediterranean areas. Over the last decades, several studies have reviewed the impact of forests on soil properties, SOC dynamics and their geomorphological and hydrological response, although few of them have intensively studied the most relevant pedological and hydromorphological consequences of afforestation, particularly in the Mediterranean mountain areas. However, during the last century, extensive afforestation was conducted by national forest services all over the Mediterranean Region, causing a sudden change in land cover. Consequently, afforestation practices may have had significant effects on a variety of environmental aspects such as landscape structure, soil properties and water and sediment yield. To address this problem, an interdisciplinary approach is proposed for understanding the global effect of afforestation on landscape structure, soil properties and carbon sequestration, and hydrological and geomorphological dynamics. This objective includes a comparison with the consequences of naturally revegetated areas (shrubs and forests) using different experimental areas in Mediterranean mountain areas. The project deals with the urgent need to implement recommendations on afforestation management, proposing a new guideline for optimized afforestation scenarios in relation to water resources and carbon sequestration, including practices for local afforestation in relation to management and strategies for regional afforestation polices.";175974,6;175974,6;FP7-PEOPLE-2013-IEF;/MC-IEF;UNIVERSITEIT VAN AMSTERDAM;NL;;;;1;0;0;1;0;0 187847;624424;ROBOTASK;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IEF;FP7;Action words Learning in a Humanoid Robot by Discovering Tool Affordances via Statistical Inference;2014-11-01;2016-10-31;http://www.robotask.eu/;Recently, humanoids have started to be employed in linguistic investigations with the dual aim of endowing robots with the capability to communicate and interact with humans, and further understanding the mechanisms underlying language development. The proposed research aims at creating a developmental cognitive model for the iCub humanoid robot for grounding the meaning of language in tool affordances. Despite it is firmly clear that language has to be grounded in sensorimotor experience, recently it has became increasingly evident the importance of going beyond simple sensorimotor grounding. To this end, statistical inference provides an original and innovative methodology that can serve in grounded theories of meaning. Computational modeling, based on statistical inference over hierarchies of flexibly structured representations, can address important problems related to human intelligence and cognition, such as the learning of language and causal relations. This research will permit to endow the iCub robot with the ability to understand language during the interaction with a human tutor and provide an experimental framework for investigating how language interacts with other cognitive processes, such as motor control. Additionally, a human-robot interaction study will permit to analyze how people experience interaction through language with the iCub robot. On the one hand, the proposed artificial cognitive system can progress theories of language learning in robots, with consequent advances in the design of human-robot communication systems, which can lead to a new generation of interactive robots. On the other hand, experiments performed on the model, by generating new predictions, can have important implications in cognitive science. The grant of the fellowship will provide the Researcher with the opportunity to further develop interdisciplinary skills in developmental robotics methods, and transferable skills for R&D in academia and service robotics industry.;179739,6;179739,6;FP7-PEOPLE-2013-IEF;/MC-IEF;FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA;IT;;;;1;0;0;1;0;0 187882;624808;TRAKIMI;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IEF;FP7;Travelling knowledge in medieval Islam: the Ash‘arites of al-Andalus and North Africa;2015-02-01;2017-01-31;;"In the context of the intellectual life of Muslim societies, systematic rational theology was traditionally seen as a discipline in its own right. It was thereby clearly distinguished from other, in many respects, similar intellectual endeavours like, for example, Graeco-Arabic philosophy. One of the most influential theological schools in Muslim history was the Ash‘ariyya. According to its self-understanding, this school sought to reconcile a rational approach towards theological issues with the limitations set by revelation. The school’s historical importance notwithstanding, major desiderata in the investigation of its variegated history and internal diversity remain. The proposed project aims to study one of the widely neglected chapters of the intellectual history of the Ash‘ariyya, namely its transmission to the medieval Maghreb, i.e. the Iberian Peninsula and North Africa. The innovative nature of this project lies in its understudied subject and its interdisciplinary approach that combines philological methods and computational technologies for social network analysis.";166336,2;166336,2;FP7-PEOPLE-2013-IEF;/MC-IEF;AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS;ES;;;;1;0;0;1;0;0 187791;623708;SQUIRREL;CAN;FP7-PEOPLE;FP7-PEOPLE-2013-IEF;FP7;Sensing Quantum Information Correlations;2014-03-01;2015-02-28;;"'Quantum correlations are those supporting technologies such as quantum information processing. For realistic applications, one has to consider open quantum systems, that is, in contact with the classical world through lifetime and excitation. Quantum correlations are transferred through emitted photons, electrons, etc. and characterise the quantum structure of the system and its suitability as a quantum device. The state-of-the-art is the Hanbury Brown-Twiss two-photon counting, which is a particular case of the general problem. At the speed of technological progress, it is now becoming possible to measure higher order correlations of quanta characterised in all their attributes. For instance, cross-correlating photons with fixed frequencies and arrival times is now a routine practice in most laboratories worldwide. The correct interpretation and mastering of such techniques will allow a robust implementation of quantum protocols. Theoretically, the computation of such correlations is extremely complicated and tedious as it needs to keep in the calculation all the degrees of freedom for each carrier. I have recently developed a general formalism, called 'the sensing method', conceptually transparent and improving computations by several orders of magnitude as compared to the previous methods. This allows to deal for the first time with complicated quantum systems, with many degrees of freedom and particles, and to compute Nth-order correlations, with N>2, at arbitrary times and frequencies. The goal of the SQUIRELL project is to develop and disseminate this novel and interdisciplinary theoretical approach in a wide range of quantum systems (cavity QED, superconducting circuits, atomic and semiconductor systems, plasmonic, Bose-Einstein condensates, etc.), by analysing the physics made accessible by the sensing method, by supporting experiments on quantum correlations in a variety of fields and by exploiting correlations to improve and design new quantum devices.'";86685,3;86685,3;FP7-PEOPLE-2013-IEF;/MC-IEF;UNIVERSIDAD AUTONOMA DE MADRID;ES;;;;1;0;0;1;0;0 187781;623612;CDH2_NEUROMIGRATION;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IEF;FP7;The cytoskeleton and Cadherin-2 are tightly linked to coordinate nucleokinesis in migrating neurons;2015-02-01;2017-01-31;;"The cerebellum coordinates the body’s movements. It consists of distinct layers of neuronal populations, but during embryonic development, these neurons are generated distantly from their final locations. In zebrafish, this means that cerebellar neurons have to migrate from the upper rhombic lip to the midbrain-hindbrain boundary and further. While descriptions of the migratory pathways for the different neuronal populations have become available in recent years, fundamental questions of this process are still unanswered. Firstly, we currently do not know how guidance of these cells is achieved and translated into directional motility. Activity could be a guiding cue, as it creates intracellular Ca2\-transients which determine directionality in cerebellar neurons. Similarly, depletion of Cadherin-2, a cell-adhesion molecule and key regulator of cell migration, leads to loss of directionality. If activity works through Cadherin-2 to guide cells, it would present a novel way of transmitting information from outside to the inside of cells. We will test this notion using the latest genetic tools. Secondly, Cadherin-2 influences centrosome-positioning, yet we do not know the molecular mechanism of this. IQGAP1 could be the link between Caherin-2 and the microtubules, but this remains to be proven. Thirdly, in order to generate movement of the cells, the forces from the cytoskeleton need to be transmitted to the nucleus. Two models for such mechanisms are being debated, and we will test both in migrating cells in vivo. To address these questions, we will use an interdisciplinary approach combining techniques and knowledge from cell biology, developmental biology and genetics with advanced in vivo time-lapse imaging. Understanding how the cells’ migration is guided and regulated will improve the fundamental knowledge for the development of therapies for patients suffering from brain injuries or lissencephalies, and create a unique focus of cerebellar research in Europe.";161968,8;161968,8;FP7-PEOPLE-2013-IEF;/MC-IEF;TECHNISCHE UNIVERSITAET BRAUNSCHWEIG;DE;;;;1;0;0;1;0;0 186950;632071;RECONFIGURATIONS;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-CIG;FP7;Reconfigurations of Centre and Periphery in the European Union: a Discursive Political Study;2014-04-01;2017-04-13;;"'The project ‘Reconfigurations of Centre and Periphery in the European Union: a Discursive Political Study’ investigates the transformation and re-definition of centre and periphery in the European Union (EU) in the aftermath of the financial crisis. It starts from the observation that Eurozone crisis not only challenged the rationality of the European Economic and Monetary Union (EMU), but also damaged the project of developmental catch-up that was at the core of EU integration and expansion since the 1980s. While the crisis shattered the peripheral growth models linked to the appreciation of the Euro, the austerity-focussed crisis management overseen by the EU and the International Monetary Fund (IMF) rendered difficult any new strategy of development in the affected countries, trapping them in persistent recession, if not political and social-humanitarian crisis. This has given rise to movements that question not only the burden-placing of crisis management, but also the model of EU economic integration and the way national economies and polities are bound up with it. However, those political forces maintained office who complied with EU/IMF credit conditionality, while the reform of the EMU upholds the established approach to economic integration through enhanced central oversight. The project investigates the hypothesis that the EU’s looming legitimation crisis has partially been contained by the discursive-symbolic construction of hierarchies between debtor and creditor states and their constituent societies. Economic interdependencies may have limited the range of plausible alternatives of crisis management and EU/IMF conditionality the scope for their democratic negotiation. However, the construction of (creditor )centre and (debtor-)periphery in multilevel political communication is likely to have delimitated the discursive space in which Eurozone crisis management could be imagined and contested. For the investigation of these assumptions, a framework is developed that combines the discourse theory and analytics of linguistic Critical Discourse Analysis with insights in the political economy, governance and political communication of European integration. The project explores discourse practices that contributed to the construction of debtor-peripheries, including the symbolic performance of EU conditionality, mediatized crisis narratives and the ostracising (self )representation of marginalized groups. They are scrutinized in secondary and primary analyses of public statements by EU representatives; as well as by rival domestic camps and ordinary people in two countries, Greece and Ireland, who gained prominence as two different models of catch-up development. The discourse analysis is situated in an analysis of EU conditionality regimes and financial-economic interdependencies that emerged since the Maastricht Treaty. Insights will be used to consolidate an interdisciplinary research programme for the investigation of centre-periphery relations within the EU. They will also inform recommendations for trainings in ‘reflexive EU literacy’ that includes the ability to switch between an EU-centric perspective and the perspective of the ‘EU-subaltern’ that is subject to processes of EU integration with little capacity for co-determination.'";75000;75000;FP7-PEOPLE-2013-CIG;/MC-CIG;STIFTUNG EUROPA-UNIVERSITAT VIADRINA FRANKFURT (ODER);DE;;;/LIF;1;0;0;1;0;0 187733;623046;CompEnz;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IEF;FP7;Quantum Chemistry of Enzymatic Nucleophilic Substitution: Untangling the Role of Metal Ions and Protein Environment in Biochemical Nucleophilic Substitution at Phosphorus and Sulfur;2014-11-01;2016-10-31;;"Enzymatic nucleophilic substitution reactions are ubiquitous as key steps in biochemical processes of living cells. Despite their importance, they are poorly understood, in particular regarding the exact mechanism and involvement of the protein environment and the role and mechanistic involvement of metal ions. Through interpretative methods from chemical reactivity theory, I will tackle the missing links in this field of molecular life sciences. This project thus goes beyond transition state calculations, which are today’s state of the art in computational enzymology, by addressing the question why. The project’s goal is to build a new research protocol to give insight in enzymatic reactions. This is original and innovative, and will as such contribute to Europe’s excellence. Through the integrated scientific and complementary skills training, it will offer much to my career development. The role of metal ions and the protein environment in triphosphate hydrolysis and sulfur oxidation reactions, which are abundant and ubiquitous enzymatic reactions involved in e.g. signal and energy transduction will be untangled via quantitative molecular orbital (MO)-theory. The MO-model and its associated energy-decomposition approach, for which the host will offer a training, can make trends in reaction barriers transparent and is the current state of the art in explanatory chemistry. This approach is only marginally used to tackle the chemistry of enzymatic reactions and gives the project its originality and pioneering nature. Further, by studying the nature of the reaction barrier of sulfur oxidation reactions, I will pioneer the field of theoretical redox protein sulfur chemistry. Sulfur redox biology is being studied extensively by biochemists, but only marginally by theoreticians. In conclusion, by studying representative proteins, this project translates fundamental chemical insights into biological relevance, giving the project its interdisciplinary nature.";183469,8;183469,8;FP7-PEOPLE-2013-IEF;/MC-IEF;STICHTING VU;NL;;;;1;0;0;1;0;0 101585;289995;ISOLATE;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-ITN;FP7;Developing single cell technologies for systems biology;2012-01-01;2015-12-31;;"'Biological cells are entities with highly complex, non-linear control circuits. They can thus express intricate behavior, such as stochasticity-induced multistability, oscillations, responses at different time scales, hysteretic behavior, memory, etc. Biology is only about to start to investigate these phenomena, which all occur at single cell level and often result in phenotypic heterogeneity. It is required to experimentally probe single cells, as population-level analyses will mask most of the behaviors of individual cells. Development of single cell measurement techniques represents an area for exciting research and development, being the key enabling technique to ultimately understand important complex biological behaviors. The education of highly qualified specialists with multidisciplinary skills is a pivotal prerequisite for addressing these biological problems and, even more importantly, for transferring this knowledge into marketable products. This proposal seeks funding for a truly interdisciplinary European consortium to train researchers to develop and exploit novel technologies for single-cell analysis in the context of system-level metabolic cell behavior. The crucial importance of single cell analysis has been stressed in a recent Science News Focus and the area of metabolism was highlighted in Nature’s “New year, new science' outlook for 2011. ISOLATE represents an Initial Training Network involving eleven trainees. A range of methodologies will be included to provide unique training to fellows in single cell analyses and to investigate complex phenomena. A high degree of multidisciplinarity and the inclusion of key industrial stakeholders make ISOLATE especially suitable for a training program ranging from forefront microtechnology, bioengineering, biophysics, via analytical chemistry to biochemistry and systems biology.'";2994929,01;2994929,01;FP7-PEOPLE-2011-ITN;/MC-ITN;GOETEBORGS UNIVERSITET;SE;"LABORATORY IMAGING SRO;KINASEDETECT APS;UNIVERSITY OF YORK;EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH;SYDDANSK UNIVERSITET;RIJKSUNIVERSITEIT GRONINGEN;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD";"CZ;DK;UK;CH;NL";"/LIF;/SCI";1;0;0;1;0;0 98942;277110;MULTIPLE-ACCESS QKD;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-RG;FP7;Multiple-Access Quantum Key Distribution Networks;2011-05-01;2015-04-30;;I propose the theoretical study of multiple-access quantum key distribution (QKD) networks. Quantum cryptography is an emerging interdisciplinary field of science and engineering with developing commercial applications. It is one of the objectives of the work programme to provide European citizens with the security level that the quantum technology offers. Multiple-access QKD networks make us one step closer to this goal, and open up new marketing opportunities by introducing more flexible configurations as compared to the current point-to-point QKD links. In a multiple-access network, every two users can use a shared channel to exchange a secure key without trusting any other users. This shared channel can be used, possibly, at the same time, by other pairs of users who also wish to create secure keys. Such an advantage becomes possible by employing the well developed multiple-access techniques in classical optical communication networks. In particular, I intend to study the three schemes of wavelength, code, and time division multiple access, in which, respectively, each user is assigned a particular wavelength, code, or time slot. The main question to answer is how the interference caused by other users will affect the rate of secure key generation in a multiple-access QKD setup. It is also important to compare different network configurations in terms of their architecture and cost. Finally, I would like to investigate the possibility of extending the ideas relevant to local and metropolitan area networks, to wide area networks, where we need to employ quantum repeaters for the secure exchange of the key. Experimental demonstration of such networks will also be pursued via finding other sources of funding or in collaboration with other research groups.;100000;100000;FP7-PEOPLE-2010-RG;/MC-IRG;UNIVERSITY OF LEEDS;UK;;;/SCI;1;0;0;1;0;0 92563;239381;REALSYMPOPENMIRROR;ONG;FP7-PEOPLE;PEOPLE-2007-4-3.IRG;FP7;Open Gromov-Witten theory, real symplectic geometry and mirror symmetry;2009-11-01;2013-10-31;;"A great deal of research in symplectic geometry has revolved around Gromov-Witten invariants, a mathematical model of the physics of closed strings. Recent research in string-theory indicates that there should be an open-string analog of Gromov-Witten invariants, despite certain mathematical complications. In my thesis, I introduced a working definition of open Gromov-Witten invariants for real symplectic manifolds. I intend to study the properties of these new open Gromov-Witten invariants, and investigate how to extend the definition further. In my thesis, I established a connection between open Gromov-Witten theory and real enumerative geometry as developed in the recent seminal work of J. Y. Welschinger. Progress in open Gromov-Witten theory should shed light on a host of problems in real enumerative geometry, especially the connection with traditional complex enumerative geometry. The study of open Gromov-Witten theory in the context of real geometry has revealed a deep and little studied relationship between real geometry and mirror symmetry. Mirror symmetry is a striking collection of conjectures originating from string-theory that predict a comprehensive duality between symplectic geometry and complex geometry. Intuition and knowledge from symplectic geometry and complex geometry can thus be combined to solve otherwise intractable problems. In recent collaborative work with R. Pandharipande and string-theorist J.Walcher, we have verified an important example of mirror symmetry in the real open Gromov-Witten setting. I believe my research, which bridges a gap between geometry and string theory, as well as my ongoing collaboration with physicists will help build a culture of interdisciplinary interaction. Moreover, I plan to convey the knowledge I have acquired in ongoing collaborative work with leading researchers in the United States to students and researchers with whom I have already developed ties in Europe.";100000;100000;FP7-PEOPLE-IRG-2008;/MC-IRG;THE HEBREW UNIVERSITY OF JERUSALEM;IL;;;"/SCI;/COO";1;0;0;1;0;0 97634;259419;ESKIN;ONG;FP7-IDEAS-ERC;ERC-SG-PE7;FP7;Stretchable Electronic Skins;2011-03-01;2016-02-29;;"Future electronic systems will be soft and elastic. I propose to explore the materials, technology and integration of stretchable electronic systems, which will transform at will, evenly coat a spherical lens, or smoothly interface with a delicate biological organ. Electronics will be anywhere as well as everywhere. The proposed programme has the potential to emulate yet another revolution in the microelectronics industry and trigger transformations in the biomedical sector. The ESKIN programme is an ambitious and highly interdisciplinary endeavour requiring expertise at the frontier of engineering, material sciences, biotechnology and neuroscience. Stretchability in an electronic system is its ability to negotiate mechanical deformations without letting them interfere with its electrical functionality. This is a novel and challenging demand on electronic device technology, which has, to date, mainly pushed for smaller scale fabrication and increased performance. Furthermore the natural compliance of biological tissues and cells calls for softer electronic biomedical interfaces. Overcoming the hard to soft mechanical mismatch will, without doubt, open up new horizons in biomedical research and its related industries. The manufacture of stretchable electronic skins will then require working out the underlying science and technology for active device materials on soft, elastic substrates. This capability will further be implemented to demonstrate various soft and elastic electronic systems ranging from stretchable displays to long-term neural implants. My philosophy is to exploit as much as possible current micro/nanofabrication techniques available for hard surfaces but to tailor them to soft surfaces , optimizing and improving them where needed, in order to ensure rapid transition to worldwide distributed consumer and healthcare products.";1499737,6;1499737,6;ERC-2010-StG_20091028;/ERC-SG;ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE;CH;;;"/PSE;/AER;/SPA";1;0;0;1;0;0 102396;290647;WWWFOREUROPE;ONG;FP7-SSH;SSH.2011.1.2-1;FP7;Welfare, Wealth and Work for Europe;2012-04-01;2016-03-31;http://www.foreurope.eu/;"'The objective of this 4-year project is to provide the analytical basis for a socio-ecological transition in Europe: the change to a new growth path with smart, sustainable and inclusive growth as is envisaged in the EU 2020 strategy. In order to support the transition, we analyse the need, the feasibility and best practice for change, specifying the institutional changes needed at all policy levels to implement these options. The old and new challenges Europe is facing define the starting point: globalisation, new technologies and postindustrialisation, demographic change and ecology in the context of welfare systems that have come under stress due to high public deficits. The vision is that Europe will become a role model for a 'high road growth path' which actively incorporates social and ecological goals, employment, gender and cultural aspects in an ambitious, forward looking way while continuing to be competitive in a globalised world. To achieve these objectives, the consortium will carry out and synthesise robust research in research areas covering the challenges to the welfare system, the biophysical dimension of socio-economic development, the identification of drivers towards socio-ecological transition, the role of governance and institutions on the European as well as the regional level. The consortium will benefit from ongoing dialogue with international experts in the form of expert panels and sounding boards, taking into account their views on the direction and feasibility for this new growth path. The project will be carried out by a consortium of 34 partners from universities and research institutes with international and interdisciplinary expertise. It represents 12 member states. High level Scientific and Policy Boards will monitor the analysis and the policy conclusions to guarantee the impact and dissemination of the results.'";10374823,91;7999858,25;FP7-SSH-2011-1;/CP-IP;OSTERREICHISCHES INSTITUT FUR WIRTSCHAFTSFORSCHUNG VEREIN;AT;"UNIVERSITEIT HASSELT;TECHNISCHE UNIVERSITAET WIEN;COVENTRY UNIVERSITY;ERNST-ABBE-HOCHSCHULE JENA;PANNON EGYETEM;RATIO;UNIVERSITE DE NICE SOPHIA ANTIPOLIS;UNIVERSITY OF DUNDEE;INSTITUT FUR WELTWIRTSCHAFT;DR.UNTIEDT & DR.ALECKE GBR GEFRA;THE UNIVERSITY OF BIRMINGHAM;ZENTRUM FUER EUROPAEISCHE WIRTSCHAFTSFORSCHUNG GmbH;Institute for World Economics of the Hungarian Academy of Sciences;EKONOMICKA UNIVERZITA V BRATISLAVE;JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN;LIBERA UNIVERSITA DI BOLZANO;HUMBOLDT-UNIVERSITAET ZU BERLIN;BUDAPEST SZAKPOLITIKAI ELEMZO INTEZET KORLATOLT FELELOSSEGU TARSASAG;POLICY NETWORK AND COMMUNICATION LTD;UNIVERSITAET KLAGENFURT;EKONOMICKY USTAV SLOVENSKEJ AKADEMIE VIED;OIR GMBH;MAGYAR TUDOMANYOS AKADEMIA KOZGAZDASAG- ES REGIONALIS TUDOMANYI KUTATOKOZPONT;ICLEI EUROPEAN SECRETARIAT GMBH (ICLEI EUROPASEKRETARIAT GMBH)*;UNIVERSITAT AUTONOMA DE BARCELONA;UNIVERSITEIT UTRECHT;UNIVERSITA POLITECNICA DELLE MARCHE;WIRTSCHAFTSUNIVERSITAT WIEN;KATHOLIEKE UNIVERSITEIT LEUVEN;UNIVERSITY OF SURREY;ÖSTERREICHISCHES INSTITUT FUR RAUMPLANUNG;ECOLOGIC INSTITUT gemeinnützige GmbH;MENDELOVA UNIVERZITA V BRNE;ASTON UNIVERSITY;IVORY TOWER AKTIEBOLAG";"BE;AT;UK;DE;HU;SE;FR;SK;IT;ES;NL;CZ";"/ECO;/SOC";1;0;0;1;0;0 105510;316966;ITECC;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-ITN;FP7;Investigating Tectonism-Erosion-Climate-Couplings;2013-01-01;2017-06-30;;"Tectonics and climate are interdependent. The tectonics of orogens are moderated by climate through erosion. Exposure of rock by tectonics or erosion is critical to the feedback which governs changes in global climate, whilst topography influences rainfall. The principle objective of iTECC is to use the Himalaya as a natural laboratory to train young scientists in understanding such coupled processes. iTECC will integrate information from sedimentary archives with work on present-day tectonics, weathering, erosion and climate. Hereto, iTECC brings together and develops expertise in: observation and modeling of the active deformation of the lithosphere; processes of weathering and erosion; study of the geological records of the past evolution of these processes; and modeling of present and past climate change. The breadth of this research provides training in observational, analytical and mathematical methods applied in Earth and environmental sciences. The proposed interdisciplinary training will result in a cohort of Earth Scientists with the cross-disciplinary expertise to enable them to tackle the problems posed in understanding the complex earth processes which moderate our surface environment. iTECC's objectives are: • Training of scientists with the ability to contribute to multi-disciplinary research ranging from solid Earth processes to climate, and apply their skills in academia and industry. • Integration of research on present-day deformation with information from the geological record to understand how the lithosphere deforms. • Significant improvement in the recovery and exploitation of tectonic, erosive, weathering and climatic records from sedimentary sequences. • Evaluation of the impact of elevation and exhumation of the Himalayas on climate. • Evaluation of the impact of climate, through erosion, on the tectonic evolution of the Himalayan orogen. • Validation of climate models, using them to verify the interconnections between tectonics and climate";4018969,9;4018969,9;FP7-PEOPLE-2012-ITN;/MC-ITN;STICHTING VU;NL;"CAIRN INDIA LIMITED;THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES;UNIVERSITAET BREMEN;UNIVERSITAET POTSDAM;UNIVERSITE JOSEPH FOURIER GRENOBLE 1;THERMO FISHER SCIENTIFIC (BREMEN) GMBH;LANCASTER UNIVERSITY;UNIVERSITE GRENOBLE ALPES;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS";"IN;UK;FR;DE";/LIF;1;0;0;1;0;0 103351;299000;REBED;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IEF;FP7;The Representation of the 'Exotic' Body in 19th-Century English Drama;2012-10-01;2014-09-30;;'REBED aims at a mapping of the presence of the 'exotic' body, that is, the cultural and physical body of the non-European Other, in 19th-century English drama, with specific attention to melodramas, farces, burlesques, pantomimes and extravaganzas. REBED aims in particular to investigate what practices and devices are employed to represent the ‘exotic’ body, to what extent the cultural, political and scientific discourses of the British Empire have influenced the dramatic representation of the ‘exotic’ body, and whether 19th-century drama was a major conveyor of racial and political values. In addressing these questions, the project ultimately aims to verify whether 19th-century English drama contributed to the forging of a politically-oriented perception of the non-European Other, and, if so, how. It will thus provide a model for further investigation on other areas, centuries and/or genres that may be of use for the framing of contemporary perceptions of non-European minorities in Europe. Although the general frame for the project is that of Drama and Literary Studies, REBED will also widely refer to disciplines such as Visual Studies, Anthropology and History of Science. In previous work, the researcher focused on 20th-century drama in English both from Great Britain and its colonies, as well as on the cultural and political (but not literary) background of 19th-century England. This project will allow the researcher to extend her expertise, as well as to develop a full interdisciplinary approach. The opportunity to work in a highly international context, to profit from specialized archives and the expertise of renowned experts, as well as to be able to develop complementary skills such as the management of dissemination and outreach events, will help the researcher strengthen her position within the academic community both in the medium and in the long term.';209033,4;209033,4;FP7-PEOPLE-2011-IEF;/MC-IEF;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;UK;;;/SCI;1;0;0;1;0;0 109411;227057;INNOVASOL;ONG;FP7-NMP;"ENERGY.2008.10.1.2;NMP-2008-2.6-1";FP7;Innovative Materials for Future Generation Excitonic Solar Cells;2009-04-01;2012-03-31;;INNOVASOL aims to develop radically new nanostructured materials for photovoltaic (PV) excitonic solar cells (XSCs) really competitive with traditional energy sources. The main objective is to leapfrog current limitations of third-generation PV devices through a drastic improvement of the materials used for assembling XSCs. The first step is the substitution of the liquid electrolytes, currently used in dye-sensitised solar cells, with solid-state hole conductors. In parallel, semiconductor quantum dots (QDs) with tuned band gap, designed to enhance the photon capture efficiency, will replace the organic dyes as light absorbers. A striking improvement is expected from multi exciton generation (MEG) effects, overcoming the Shockley-Queisser efficiency limit of 31% for the PV conversion. In a second step, highly innovative QDs will be designed and synthesized: the QDs will be covered by self-assembled monolayers of amphiphilic dye molecules, mimicking the photosynthetic antenna system. The dye molecules will act as molecular relays (MRs), which connect the QDs to the transparent conductive oxide (TCO). Novel TCO architectures will be developed for efficient interface energy transfer and electron diffusion. Six academic institutions guarantee an interdisciplinary research, based on top level theoretical and experimental approaches. The high degree of knowledge of solid-state physics and chemistry, nanoscience and nanotechnology of the researchers assures that the new concepts and the objectives proposed will be successfully developed/pursued. Fiat research center and Solaronix, a SME leader in the XSCs production, will provide proof-of-concept prototypes to validate the innovative materials developed by the academic partners. Materials and technological solutions of INNOVASOL are original and will pave the way for future generation XSCs alternative to devices so far developed both inside and outside Europe.;4002760,02;2899510;FP7-ENERGY-NMP-2008-1;/CP;UNIVERSITA DEGLI STUDI DEL PIEMONTE ORIENTALE AMEDEO AVOGADRO;IT;"UNIVERSIDADE ESTADUAL DE CAMPINAS;THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;CENTRO RICERCHE FIAT SCPA;UNIVERSITA DEGLI STUDI DI TORINO;ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE;SOLARONIX SA;TECHNISCHE UNIVERSITAET DRESDEN";"BR;UK;IT;CH;DE";/OET;1;0;0;1;0;0 104437;306476;FIRST;ONG;FP7-IDEAS-ERC;ERC-SG-PE9;FP7;The first stars and galaxies;2012-10-01;2017-09-30;;"The FIRST proposal has the goal of investigating the nature and properties of the first stars and galaxies. The project will exploit synergies between observational cosmology, galaxy formation and stellar evolution. Observations made using large ground-based and space-borne telescopes have probed cosmic history all the way from the present-day to ~ 700 million years after the Big Bang. Earlier on lies the remaining frontier, where the first stars and galaxies formed. Data collected in the last decade have revealed that the Universe at redshift ~ 7-8 is already mature, with galaxies and quasars already formed, many with metal-rich and dust-rich signatures of even earlier generations of stars. Despite these remarkable progresses, the nature of the first stars and black holes, and the impact they had on their environment and on the properties of the first galaxies and quasars remain largely unknown. The proposed research program aims to address two main scientific objectives: (1) Understand the evolution of the first metals and dust and their role in setting the characteristic masses of stars and seed black holes; (2) Assess the properties of the first galaxies and quasars. These goals will be addressed following an interdisciplinary approach which involves theoretical models of stellar evolution and nucleosynthesis, semi-analytical and numerical models of galaxy evolution, and detailed comparison with observational data from surveys at low and high redshifts. New numerical techniques will be developed, with potential applications that go beyond the primary goals of FIRST. The results will provide new insights on the nature of the first stars and galaxies and will be of important guidance for interpreting data from ongoing surveys (HST, Spitzer, IRAM, ALMA) and for the preparation of key programs with future large telescopes (ELT, JWST).";882807,6;882807,6;ERC-2012-StG_20111012;/ERC-SG;ISTITUTO NAZIONALE DI ASTROFISICA;IT;;;"/PSE;/AER;/SPA";1;0;0;1;0;0 103243;302635;HyCode;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IEF;FP7;Atom chips on the submicron scale: Routes to hybrid cold atom-quantum electronics devices;2012-10-01;2014-09-30;;"This project merges two very successful branches of science, solid state and ultra cold atom physics. Although a combination of quantum systems from each of these fields is of great interest, interactions between the two fields remain rare. In this project we will develop a platform to cool and trap ultracold rubidium gases in the submicron vicinity of novel types of atom chips (current chips: 10-100 microns).Only at this distance scale, efficient, fast and sufficiently strong controlled coupling between the atomic and the solid state based quantum electronic system will be possible. The close surface limitations can be beaten by reducing influences of Casimir-Polder surface attraction, Johnson noise and trapping potential roughness due to fabrication imperfections.The project encompasses fabrication of thin membrane atom chips with two-dimensional electron gases (2DEG) and magnetic materials coupling to ultracold thermal and Bose-condensed atomic samples at submicron distances. As a first application we will map out and control the current and donor distribution of a 2DEG. This project is set within the Midlands Ultracold Atom Research Centre at the University of Nottingham interlinking scientists and research at the interface between atomic and condensed matter physics. The project brings a researcher who constructed a pioneering cryogenic cold atom apparatus at TU Vienna into the cold atom group of Scientist-in-Charge Prof. Peter Krüger with its experience in quantum gases and atom chips. In this thriving environment fast development of novel hybrid devices can be expected with quantum technology applications ranging from quantum information processing to metrology (Casimir forces, minute magnetic field patterns). Hence this project targets areas of national and European priority in an interdisciplinary area of leadership of science and technology within the European Research Area.";209033,4;209033,4;FP7-PEOPLE-2011-IEF;/MC-IEF;THE UNIVERSITY OF NOTTINGHAM;UK;;;/SCI;1;0;0;1;0;0 110103;612257;COMANDER;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IAPP;FP7;Converged Optical-Mobile Access Networks with Dynamic and Efficient Resource allocation;2013-10-01;2017-09-30;;"'Total 108 6 114 7 42 4 0 0 0 0 COMANDER aims at bringing together experts from the industry and academia with the long-term goal of delivering a state of the art, cutting-edge and cost-efficient approach to the problem of Next-Generation access Networks (NGN) design. The design of NGN has since long dictated the necessity to merge the currently distinct optical and wireless infrastructures into an amalgamated network capable of offering the best part of both worlds: the stability and ultra-high speeds of optical fiber networks with the agility and flexibility of wireless networks. To achieve this goal COMANDER employs a novel design that builds upon the Radio-over-Fiber paradigm, and proposes all the necessary solutions to overcome the existing limitations. Moreover COMANDER goes beyond the architectural convergence by addressing for the first time the matter of NGN intelligence that will unleash the full capabilities of the unified Fiber-Wireless architecture. The scale and diversity of the NGN vision calls for the cooperation of many interdisciplinary experts from the fields of optical communications, wireless engineering, protocol design, network coding and simulation that up to now operated independently. COMANDER achieves these objectives via the fruitful collaboration of four partners, two from academia, i.e., Aristotle University of Thessaloniki (AUTH) and Technical University Berlin (TUB), and two SMEs, i.e., PhoeniX Software B.V. (PHX) and iQuadrat (IQU). As a whole, the partners have consolidated and complementary expertise in the engineering, design, analysis, simulation and experimentation that are demanded to fulfill the project’s goals.'";2326807,12;2326807,12;FP7-PEOPLE-2013-IAPP;/MC-IAPP;ARISTOTELIO PANEPISTIMIO THESSALONIKIS;EL;"TECHNISCHE UNIVERSITAET BERLIN;IQUADRAT INFORMATICA SL;PHOENIX BV";"DE;ES;NL";/LIF;1;0;0;1;0;0 100302;286269;STAR-AGROENERGY;ONG;FP7-REGPOT;REGPOT-2011-1;FP7;Scientific & Technological Advancement in Research on Agro-Energy: an integrated approach to renewable energy generation according to sustainability criteria;2011-09-01;2015-08-31;http://www.star-agroenergy.eu/;"The project is aimed at developing the research potential of the University of Foggia (UFG); three parallel strategic pathways are planned: improving the research activities through an interdisciplinary approach (“bonding” by research integration inside UFG); consolidating a critical mass of researchers (“bridging” by recruitment outside UFG); expanding the research network through large and qualified scientific and non-scientific collaborations (“linking” through two-way secondment collaborations and institutional partnerships). Other, equally relevant, complementary actions are included: upgrading the R&D facilities; dissemination and promotional activities; research evaluation. One major strength of the proposal is its unusual, high level of integration between the two major drivers of scientific and technological innovation: “research community” and “local stakeholders”. The world energy economy is currently undergoing a critical period of transformation in technology, governance, social and economic values of energy. A new economics of energy is heralded by national and international negotiations and the assumption that economic growth can be supported largely by fossil fuels is fading rapidly. To face such challenges and exploit new opportunities it is imperative to develop novel, renewable sources of energy, be selected in dependence of cultural, social, economic and environmental conditions of the specific regions. “Agro-energy” is the topic addressed by the project: obtaining renewable energy through productive activities complementary to farming. The project aims at building up a methodology to reconcile energy production with the ecological harmony and the cultural heritage of the most relevant rural areas of Southern Europe. This project strives to work out models of sustainable dispersed bioenergy generation and proximal energy consumption. A passionate debate is raging around agro-energy. Someone maintains the position of fossil energy as more efficient than bioenergy and claims that “producing feedstock for energy rather than food is a crime against humanity”. In contrast, others support the ecological validity of agro-energy production. A trade-off can be found in order to secure a fully sustainable technological development which does not affects the cultural heritage, the territory and the landscape.";3748715,2;3370012;FP7-REGPOT-2011-1;/CSA-SA;UNIVERSITA DEGLI STUDI DI FOGGIA;IT;;;/REG;1;0;0;1;0;0 110095;607607;CALIPSO;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-ITN;FP7;Calcium- and light signals in photosynthetic organisms;2013-10-01;2017-09-30;;CALIPSO is a genuine interdisciplinary and intersectorial research network composed of nine academic research institutions and three industrial partners, thus presenting an example of true translational research and training of young researchers in communicating and transferring achievements from different model organisms directly to industrial partners. CALIPSO aims at identifying environmentally triggered regulatory calcium signals and protein phosphorylation events that control photosynthesis and metabolism. CALIPSO partners work with a wide range of different organisms covering the full phylogenetic spectrum from algae to higher plants including economically important crops. They combine a wide spectrum of newest technologies in molecular biology, biochemistry, proteomics, metabolomics, genetics, bioinformatics and systems biology to uncover how photosynthetic organisms acclimate to changing environmental conditions or stress. This novel combination of scientific expertise combined with industrial applications is one of the major strengths of CALIPSO, exposing the participating researchers to different “schools of thought”. The active participation of Bayer CropScience Gent and Ecoduna as full network partners, and Photon Systems Instruments as associated partner, will enable intersectorial industry-academia cooperation with the long term objectives of (i) improving yield and stress robustness of crops and (ii) developing microalgal-biotechnology. The integrated systematic training programme of CALIPSO will boost the future employability of the young researchers by acquisition of technical skills for their work in academia or the private sector and also essential complementary skills for their future career. The training programme comprises three workshops on state-of-the art techniques - and one on industrial-relevant skills. This is completed by secondments to partner laboratories and industry and network-wide training events in further complementary skills.;3408898,24;3408898,24;FP7-PEOPLE-2013-ITN;/MC-ITN;UNIVERSITAT WIEN;AT;"UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6;LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN;ECODUNA PRODUKTIONS-GMBH;UNIVERSITE DE GENEVE;UNIVERSITY OF DURHAM;RHEINISCHE FRIEDRICH-WILHELMS-UNIVERSITAT BONN;GREGOR-MENDEL-INSTITUT FÜR MOLEKULARE PFLANZENBIOLOGIE GMBH;BAYER CROPSCIENCE NV;UNIWERSYTET JAGIELLONSKI;JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN;TURUN YLIOPISTO";"FR;DE;AT;CH;UK;BE;PL;FI";/LIF;1;0;0;1;0;0 96320;253990;COMIC;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IOF;FP7;Cooperative Multipoint Transmission for Interference Coordination;2010-09-01;2013-08-31;;COMIC aims at defining Cooperative Multipoint (CoMP) techniques focused on interference mitigation based on efficient scheduling design and beamforming. These techniques will be divided into two groups. In a first phase a set of ideal techniques will be proposed assuming a perfect knowledge of the system state (users’ location, speed, bit error rates, etc.). A huge number of variables will be taken into account, thus increasing the complexity of these optimization problems. This group of techniques will be used as a reference to test the performance of a second group of more realistic techniques defined in a second phase. For these techniques, not all variables will be known and, moreover, there may be errors in measurements. Comparing the first and second group, the best realistic technique will be identified depending on their behaviour, errors impact and complexity. The design of all these algorithms will be carried out at Carleton University (CARLETON) during the first two years of fellowship. The mathematical requirements for completing this task compel to closely work with an expert group in telecommunications and applied mathematics like CARLETON. During the return phase at the Polytechnic University of Valencia (UPVLC), COMIC will focus on implementation aspects of the best algorithms. Therefore, COMIC not only aims at studying theory aspects but also at evaluating practical implementation problems. Hence, all conclusions arisen from the outgoing phase will be experimentally validated using the simulation and radio-over-fiber platforms available at UPVLC. The interdisciplinary aspects of the outgoing and return phases correspond with the expertise of each host. Thanks to the theoretical and practical aspects that will be studied in COMIC, the results of this project are expected to have a huge impact.;209248,3;209248,3;FP7-PEOPLE-2009-IOF;/MC-IOF;UNIVERSITAT POLITECNICA DE VALENCIA;ES;;;"/LIF;/EDU";1;0;0;1;0;0 95631;254402;ROSES;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IOF;FP7;Robust and Self-organizing Networks;2010-08-01;2012-07-31;;Networks in transport, logistics, and telecommunication are pivotal for European and similar modern societies. The networks are complex and of very large scale. They must be operated both efficiently and reliable. At the intersection of mathematics, computer science, economics and engineering a huge body of linear and discrete network optimization methods has been developed. Methods for robust optimization form a younger field, topically attracting a lot of attention both mathematically and from practice. Recently, the concept of Recoverable Robustness, which we developed in an FET project, has significantly enlarged the possibilities to combine robustness and network optimization. The concept is well understood and proved useful in practice when the recovery is a linear program. The case when the recovery is an integer linear program has far broader modeling power. This case is almost untreated. In many applications the networks are not controlled by a central optimizing authority. They are operated by selfish players. A market mechanism must guarantee that the players in pursuit of their own benefit achieve global efficiency and reliability. Mechanism design is a thriving field with high international and interdisciplinary visibility. While many mechanisms for optimization problems are known, mechanisms that instill robust solutions are untreated. Given a market mechanism to instill robustness in a network controlled by selfish players at minimum loss in efficiency, a different application stands to reason: the networks created by credit obligations. To design regulations yielding robust credit networks it seems reasonable to complement classical, stochastic techniques with robust network optimization and algorithmic game theory. Such a new approach will have huge impact both scientifically and on financial stability. MIT’s ORC offers leading experts to cooperatively extend robustness to integer recovery, mechanism design and financial risk management.;207628,4;207628,4;FP7-PEOPLE-2009-IOF;/MC-IOF;TECHNISCHE UNIVERSITAET BERLIN;DE;;;"/LIF;/EDU";1;0;0;1;0;0 95637;256547;CEREPEP;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-RG;FP7;Peptide Crystal Engineering with Lanthanide Complexes;2010-09-01;2013-08-31;;Crystal engineering will be used to combine rare earth complex chemistry with peptide synthesis in order to prepare new crystalline supramolecular and polymeric materials. Rare earth containing metallopeptides with luminescent and magnetic properties will be targeted as model compounds for applications in medical and biochemical research (e.g. biological imaging, contrast agents, etc). This approach will involve interdisciplinary collaborations to produce and analyse new materials for medicinal or biological chemistry. The preparation of peptides as molecular building blocks for the synthesis of supramolecular compounds will demand specialist expertise in different sectors of chemistry, biology and physics. The solvent-less green synthesis of coordination polymers, supramolecular frameworks and materials will also be developed as a new direction in existing projects, which the applicant initiated during the Marie Curie Fellowship. New molecular solid-state synthesis will present the potential to initiate local and international collaborations with academia and industry.;45000;45000;FP7-PEOPLE-2009-RG;/MC-ERG;UNIVERSITY OF NEWCASTLE UPON TYNE;UK;;;/SCI;1;0;0;1;0;0 109647;337752;DIRECTEDINFO;ONG;FP7-IDEAS-ERC;ERC-SG-PE7;FP7;Investigating Directed Information;2013-08-01;2019-07-31;;"This research investigates a new measure that arises in information theory called directed information. Recent advances, including our preliminary results, shows that directed information arises in communication as the maximum rate that can be transmitted reliably in channels with feedback. The directed information is multi-letter expression and therefore very hard to optimize or compute. Our plan is first of all to find an efficient methodology for optimizing the measure using the dynamic programming framework and convex optimization tools. As an important by-product of finding the fundamental limits is finding coding schemes that achieves the limits. Second, we plan to find new roles for directed information in communication, especially in networks with bi-directional communication and in data compression with causal conditions. Third, encouraged by a preliminary work on interpretation of directed information in economics and estimation theory, we plan to show that directed information has interpretation in additional fields such as statistical physics. We plan to show that there is duality relation between different fields with causal constraints. Due to the duality insights and breakthroughs in one problem will lead to new insights in other problems. Finally, we will apply directed information as a statistical inference of causal dependence. We will show how to estimate and use the directed information estimator to measure causal inference between two or more process. In particular, one of the questions we plan to answer is the influence of industrial activities (e.g., $\text{CO}_2$ volumes) on the global warming. Our main focus will be to develop a deeper understanding of the mathematical properties of directed information, a process that is instrumental to each problem. Due to their theoretical proximity and their interdisciplinary nature, progress in one problem will lead to new insights in other problems. A common set of mathematical tools developed in";1224600;1224600;ERC-2013-StG;/ERC-SG;BEN-GURION UNIVERSITY OF THE NEGEV;IL;;;"/PSE;/AER;/SPA";1;0;0;1;0;0 90787;237309;IRMA;ONG;FP7-PEOPLE;FP7-PEOPLE-IEF-2008;FP7;Information Role Models with Applications;2009-06-01;2011-11-30;;"Picking a role model is a natural way of deciding what to do by emulating a person we admire: children look up to superheroes; chemists and physicists follow Marie Curie. When faced with a difficult choice, solving the problem on our own may seem difficult. Instead, we seek shelter behind our role model and try to imagine what Superman or Marie Curie would have done. There is a parallel to this approach in statistical signal processing. Consider the design of an estimator based on low quality observations. Bayesian theory dictates rules for the optimal design of such an estimator. Suppose there exists a better estimator that has access to superior observations. We can use this better estimator as a role model, and train our estimator to imitate its outputs. Under certain conditions, we have proved that this role-model approach gives the same optimal solution as the Bayesian approach, albeit with a different design methodology that is easier to implement. The motivation for this approach is in adaptive receiver design for wireless communications. During the proposed fellowship, we plan to extend the theory for the role-model framework, to refine its application to receiver design, to study its connection with other problems in information theory, and to investigate possible interdisciplinary applications. For wireless communications, the project will result in optimized low-complexity receiver structures that can save power, increase radio coverage and data integrity, and reduce the cost of mobile handsets. Further applications of role models may include computer science, risk assessment, image processing, and others.";237684,37;237684,37;FP7-PEOPLE-IEF-2008;/MC-IEF;THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;UK;;;"/SCI;/EMP";1;0;0;1;0;0 91767;240332;UFO;ONG;FP7-IDEAS-ERC;ERC-SG-PE8;FP7;Uncovering the origins of friction;2009-09-01;2014-08-31;;Nanotechnology is a new frontier in research and new tools must be developed. As surface to volume ratios become large, engineering at the nanoscale will be dominated by surface science. The study of Contact Mechanics at nanoscales nanotribology- needs to fully account for adhesive forces, third-body interactions and deformation mechanisms at contacting asperities. Understanding these factors as well as the morphological evolution of contact clusters has the potential of explaining the origins of frictional forces and wear. This will guide us in the design of tailored-made lubricants and surface morphologies, which, in turn, will help reduce the high societal cost of wear damage. This ERCstg proposal describes a plan to establish a world-leading group in Contact Mechanics at length scales ranging from the atomic to macroscopic scales relevant to Civil or Mechanical Engineering structural applications. Our approach will have recourse to molecular dynamics coupled with the finite-element method for an accurate description of atomic interactions at the contact surface, and of long-range elastic forces. The project is interdisciplinary as the deepening of our understanding of Contact Mechanics will necessitate Computer Science developments. A central objective of the research will be the release of an open, 3D parallel, finite-element platform dedicated to contact applications. The PI will assemble a team of Engineers and Computer Scientists to ensure a successful and perennial diffusion in the European academic and industrial network. The research will therefore explore the origins of friction, a scientific quest of fundamental importance to many industrial applications, and will also create a stable base for sharing scientific-computing resources.;1773000;1773000;ERC-2009-StG;/ERC-SG;ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE;CH;;;"/PSE;/EAR";1;0;0;1;0;0 93342;238353;STRONGNET;ONG;FP7-PEOPLE;FP7-PEOPLE-ITN-2008;FP7;Strong Interaction Supercomputing Training Network;2010-01-01;2013-12-31;;The research aims at a deeper understanding of properties of strongly interacting matter. This is mainly done by means of numerical simulations of the underlying theory (QCD) on supercomputers (Lattice QCD). We wish to understand QCD for its own sake and as a prototype of a strongly interacting fundamental theory. Therefore we will calculate the spectrum of mesons, baryons and of exotic states, their decays and their internal structure. We will also address questions of a purely quantum field theoretical nature that are also of interest to string theorists. In order to forward our understanding of matter under extreme conditions, i.e. at high temperatures like in the early universe and at high densities such as those inside of neutron stars we will calculate the phase diagram of QCD with light sea quarks and the equation of state at high temperatures. A sound description of QCD is indispensable for identification of physics beyond the Standard Model. Accurate calculations of certain QCD matrix elements are required. We will e.g. contribute to improving the upper limit on the CP violating so-called QCD Theta-angle and to theoretical predictions of mixing in the neutral D-Meson system. State-of-the-art supercomputers will be pushed to their limits. Hence the project includes a strong interdisciplinary component. The improvement of numerical algorithms and the optimization of software play important roles in such calculations. The development of computer hardware represents an essential part of the network activity. Interested researchers will have the chance of getting involved into this. The research provides a solid training in the analytical skills needed in quantum field theory and in particle physics phenomenology. The researchers will receive training in high performance and grid computing and in software development. Such skills are needed in academia as well as in quantitative finance, IT, oil exploration etc.;4721441;4721441;FP7-PEOPLE-ITN-2008;/MC-ITN;UNIVERSITAET REGENSBURG;DE;"UNIVERSITA DEGLI STUDI DI PARMA;THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN;AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS;BERGISCHE UNIVERSITAET WUPPERTAL;THE UNIVERSITY OF LIVERPOOL;UNIVERSITAET GRAZ;UNIVERSITY OF CYPRUS;UNIVERSITAET BIELEFELD;THE UNIVERSITY OF EDINBURGH";"IT;IE;ES;DE;UK;AT;CY";"/SCI;/EDU";1;0;0;1;0;0 103039;303880;SCOPE;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-CIG;FP7;Stress and Coping among Portuguese Police Officers;2012-04-01;2016-03-31;;"Police work has been identified as one of society´s most stressful occupations. The exposure to stressors over time can lead to several problems to the individual (physical and psychological health) as well as to the police force and other citizens. It is therefore crucial to have a proactive, well trained, dedicated, and healthy police force that performs to the best of their ability or, in other words, engaged police officers. Despite previous research recommendations, few longitudinal studies have compared stress and coping among police officers in academy and one year later on duty. Furthermore, reduced number of studies has investigated acute stress among police officers in real world conditions in Europe. In this way, SCOPE shall fulfil these gaps in the literature by proposing a novel and interdisciplinary approach combining expertise in psychology, engineering and computer science from collaborators at the University of Porto (UP). The longitudinal method will assess stress and coping among recruit police officers in academy and one year later on duty. Furthermore, SCOPE shall leverage the fellow´s previous research experience and collaborations at UP to analyse the nature of acute stressors, stress reactivity and coping strategies in real world conditions using a real-life system combining non-intrusive, user friendly technology and a Virtual Reality environment. SCOPE is based on a protocol between PSP (Public Security Police, Portugal) and FPCEUP (Faculty of Psychology and Educational Sciences, UP) and has received ethical approval by both institutions. It is believed that the novel findings will assist in the development of practical interventions enhancing a better training and performing, healthier police force and impact the safeguard of the European community. SCOPE will add an outstanding contribution to the European Union research excellence, and further develops the fellow career and her potential professional integration at UP.";100000;100000;FP7-PEOPLE-2011-CIG;/MC-CIG;UNIVERSIDADE DO PORTO;PT;;;/SCI;1;0;0;1;0;0 88342;214810;FANTOMAS;ONG;FP7-PEOPLE;PEOPLE-2007-1-1-ITN;FP7;Femtosecond opto-magnetism and novel approaches to ultrafast magnetismat the nanoscale;2008-10-01;2012-09-30;;The aim of this proposal is to create a training network in the newly-emerging multidisciplinary field of “nano-opto-magnetism”, a new scientific area with novel technological opportunities at the junction of coherent nonlinear optics, nanoscience and magnetism. The impact on society of this newly emerging field is potentially very high, therefore it is decisive that now young researchers are trained and equipped, so that they can become future leaders. We aim at achieving this by an integrated combination of a high-quality training program and their direct involvement in front-line research. In the research program we want to investigate nonthermal effects of light on nanomagnets in order to obtain a comprehensive understanding of physical mechanisms leading to a highly efficient ultrafast (10-12 seconds and faster) optical control of magnetism at the nanoscale. Such scientific breakthroughs are expected to develop novel technology for unprecedented fast (THz) opto-magnetic recording. A high-level training program firmly embedded in a consortium of both academic and industrial partners is designed to create a unique training environment to educate a new generation of young researchers in this interdisciplinary, recently emerging area of nano-opto-magnetism. In order to advance the young researchers career development, the industrial relevance of this research as well as the involvement of industrial partners is fully exploited. In addition to the scientific and networking training, this offers unique opportunities for training of complementary skills of the fellows such as training in intellectual property rights, patent writing, commercial exploitation of the results and research-and-development policy.;3057350,88;3057350,88;FP7-PEOPLE-2007-1-1-ITN;/MC-ITN;STICHTING KATHOLIEKE UNIVERSITEIT;NL;"UNIVERSITAET REGENSBURG;FORSCHUNGSZENTRUM JULICH GMBH;Uniwersytet w Bia³ymstoku;UPPSALA UNIVERSITET;UNIVERSITY OF YORK;PAUL SCHERRER INSTITUT;JULIUS-MAXIMILIANS UNIVERSITAET WUERZBURG;SEAGATE TECHNOLOGY IRELAND;TECHNISCHE UNIVERSITEIT DELFT;BERLINER ELEKTRONENSPEICHERRING-GESELLSCHAFT FUER SYNCHROTRONSTRAHLUNG GMBH";"DE;PL;SE;UK;CH;NL";"/EMP;/SOC;/EDU";1;0;0;1;0;0 89699;220582;RESRUSENVHISTORY;ONG;FP7-PEOPLE;PEOPLE-2007-4-2.IIF;FP7;Changing attitudes towards living natural resources in the Russian/Soviet Empire and the exchange of knowledge with Europe: an environmental history perspective;2009-02-02;2010-03-01;;"This interdisciplinary project aims to provide new historical knowledge about both the patterns of use of living resources in Russia and the Soviet Union, and the exchange of resource use information with Europe. Based upon methods derived from environmental history and history of science, it addresses three key objectives: to analyze changes in attitude towards living resources by different social groups and institutions in Russian/Soviet society; to throw light upon the conflict between international scientific knowledge about resources deployed by the state, and local knowledges; and to consider exchanges of knowledge about resources, their use and users at international level, especially through international exhibitions and World Fairs. The process of changing attitudes towards resources, this being a manifestation of modernization all over the world, had a particular specificity in Russia, considered one of most important factors to have shaped Russia’s distinctive development path in historical perspective. The project will enhance understanding of this specificity, as well as the analysis of knowledge exchange between Russia and Europe, which was vital to both sides but also served to underline the different contexts in which knowledges and practices evolved in the two regions. This issue has never previously been analyzed using materials from several historical periods from the formation of the Russian Empire at the beginning of the 18th century to the high point of the Soviet “Empire” in the mid-20th century. The objectives of the project will be achieved through detailed studies against the rich historical context of particular historical cases, for which the archival materials and literature have already been identified.";127158,64;127158,64;FP7-PEOPLE-2007-4-2-IIF;/MC-IIF;THE UNIVERSITY OF BIRMINGHAM;UK;;;"/SCI;/COO";1;0;0;1;0;0 99630;287485;MONTENIGHT2011;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-NIGHT;FP7;Researchers' Night in Montenegro 2011;2011-05-01;2011-11-30;;'The Researchers Night in Montenegro 2011 project will continue the success story of the Nights 2009 and 2010, organized by the same consortium, Montenegrin Science Promotion Foundation – PRONA, Ministry of Science and Natural History Museum, in bridging the gap between the researchers and wider public. All events will take place on Friday, 23 September, from 12 – 24, with the central events (Hands-on-experiments, Science and Art installations, Gala opening, Movie projections, Presentation of interdisciplinary and inter-generational workshops, ‘Open science show’, Astronomical workshop, Science kindergarten, Concert) happening in Podgorica – Ribnica river bank and a series of smaller scale activities in Podgorica (University of Montenegro) and two other towns in Montenegro (Nikšiæ and Kotor). Target groups of the projects are: high school students, university students, young people in general, preschool children, elementary school pupils, parents, school authorities and teachers, media and general public. It is planned to have at least 3500 of direct participants, and to cover about 40% of Montenegrin population or 250000 people with awareness campaign. At least 200 people, from which 50 researchers coming from different sectors and fields of research, will implement the Researchers’ Night’s activities. The main aim of 2011 project is to fulfill the goal of this EU - Marie Curie action that is to enhance the role of researchers in the mainstream of the society. Project Researchers’ Night is fun, educational and unique event that gathers general population and researchers from academic institutions, the business sector, various NGOs, governmental institutions, international agencies, including guests from around the region and young-talent programs.';37349,5;35000;FP7-PEOPLE-2011-NIGHT;/CSA-SA;"""Fondacija za promovisanje nauke """"PRONA""""""";ME;"J.U. PRIRODNJACKI MUZEJ CRNE GORE PODGORICA;MINISTARSTVO NAUKE";ME;/SCI;1;0;0;1;0;0 87659;221441;OBJECTIVE SCIENCE;ONG;FP7-PEOPLE;PEOPLE-2007-2-1.IEF;FP7;Quantifying Objectivity in the Natural and Social Sciences;2008-05-01;2010-04-30;;Every year, over 1.4 million scientific articles are published worldwide. How many of them are objective and unbiased descriptions of real phenomena? Increasing evidence suggests that malpractice and publication bias are seriously affecting modern research. Their effects, combined with biased science communication, are potentially distorting scientific knowledge to an unprecedented degree. Research agendas and political agendas risk being misdirected, and human and financial resources risk being wasted on scientific questions that are based on false assumptions. The nature and gravity of this phenomenon, as well as its consequences, are only starting to be investigated. The project aims at assessing the level of bias in the natural and social sciences by focusing on three fundamental phases in the production of scientific knowledge: data collection, publication, and popularization of results. With interviews and a survey sent to thousands of European researchers in all scientific fields (astronomy, biology, chemistry, earth science, physics, sociology, economics, political science), the project will investigate research malpractice (e.g. data falsification, fabrication, plagiarism) in Europe. With advanced statistical techniques and a very broad data set, it will quantify publication bias in all scientific disciplines, producing the first comparative and interdisciplinary study of this phenomenon. By analysing discourse and narrative in popular science articles and in editorials of scientific journals, it will investigate public’s attitude towards research integrity and bias. The project will contribute to maintaining the reputation of excellence of European research, and it will be of great interest to decision makers and to scientists in all disciplines. In addition, it will allow the fellow to train in many techniques of social research, and to resume a scientific career addressing a largely unexplored field of study.;161792,99;161792,99;FP7-PEOPLE-2007-2-1-IEF;/MC-IEF;THE UNIVERSITY OF EDINBURGH;UK;;;"/SCI;/EDU";1;0;0;1;0;0 90584;235237;ACTIVOXY;ONG;FP7-PEOPLE;FP7-PEOPLE-IEF-2008;FP7;Oxygen Activation in Ribonucleotide Reductase and Multicopper Oxidases Proteins;2009-06-01;2011-05-31;;Boundaries among biological, chemical and physical domains are nowadays fading, and the complex phenomena observed in Nature as well as in artificial systems can only be tackled from a broader/interdisciplinary perspective. In this context, the biological activation of the molecular oxygen is a fascinating and yet complex process. The ability to store, transport and utilize this simple molecule gated evolution of life in our planet and led to growth and selection of a variety of organisms. Complex molecules selected by Nature as active in “key metabolic paths” of the oxygen in life often contain copper and/or iron metal ions as reactive centres. A wide variety of experimental results and theoretical investigations show that the metallo-oxygen interactions have dominant states that are not spatially homogeneous (anisotropy). These effects occur when a number of physical interactions such as spin, charge, lattice (crystal-field), and/or orbitals are simultaneously active. The result of these interlocked numbers of factors links biology to chemistry and molecular physic, and allow the oxygen to be used in different ways within metabolism. The research proposal presented herein aims to investigate the red/ox mechanism and the connected energetic of the oxygen activation process in a series of di-iron (Ribonucleotide Reductase, RNR, Class I R2) and copper protein (multicopper oxidases) through the use of spectroscopic methods (EPR X-Q, high field EPR, CD, MCD, rR resonance Raman), structural (X-ray) and kinetic analyses (stopped flow, cryoenzymology). The endeavour is directed towards a better understanding of the geometric and electronic structure of metal-oxygen interactions that contribute to define O2 reactivity. These studies will provide molecular level insight into oxygen and metal metabolism, disease states, bioremediation and possible the development of efficient drugs inhibitor.;;202542,89;FP7-PEOPLE-IEF-2008;/MC-IEF;UNIVERSITETET I OSLO;NO;;;"/SCI;/EMP";1;0;0;1;0;0 92114;237920;UNILHC;ONG;FP7-PEOPLE;FP7-PEOPLE-ITN-2008;FP7;UNIFICATION IN THE LHC ERA;2009-10-01;2013-09-30;;"The main research theme of the proposed network is the theoretical interpretation of results coming from the LHC and other experimental and observational sources. The aim is to identify the physics Beyond the Standard Model of strong, weak and electromagnetic forces and ultimately to provide a fully unified description of the fundamental states of matter and their interactions. We will investigate the nature of electroweak symmetry breaking, the origin of masses and their hierarchies and the quantization of the gravitational interaction. The methodology is based on three main ingredients: symmetry, including supersymmetry and symmetries related to flavor, string unification and new space dimensions. The research objectives are: (a) probing the origin of mass at the LHC; (b) search for supersymmetry; (c) the physics of flavor in the LHC era; (d) exploring extra dimensions; (e) cosmological and astrophysical challenges for physics beyond the Standard Model; (f) string theory, string phenomenology and Quantum Gravity. The network will enhance the current collaboration amongst the participating European institutions, which already plays a leading role across the whole spectrum of the physics involved, from theoretical aspects of string theory to the phenomenological analysis of experimental data, and it will stimulate interdisciplinary interactions. The main network goal is to offer excellent initial training to young researchers. We plan to appoint 456 person-months of early-stage and 108 months of experienced researchers, and develop a training program both at the individual and network-wide level. The network is structured to develop the research and complementary skills of the young researchers, to ensure their mobility and to widen their career prospects. In this way, we intend to increase the pool of European researchers at the highest level of scientific excellence, and to make a significant contribution to the development of European fundamental research.";3673966,6;3673966,6;FP7-PEOPLE-ITN-2008;/MC-ITN;ECOLE POLYTECHNIQUE;FR;"UNIWERSYTET WARSZAWSKI;ARISTOTELIO PANEPISTIMIO THESSALONIKIS;COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES;UNITED NATIONS EDUCATIONAL, SCIENTIFIC AND CULTURAL ORGANIZATION -UNESCO;UNIVERSITAT DE VALENCIA;RHEINISCHE FRIEDRICH-WILHELMS-UNIVERSITAT BONN;EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;UNIVERSIDAD AUTONOMA DE MADRID;INSTITUTO SUPERIOR TECNICO;ISTITUTO NAZIONALE DI FISICA NUCLEARE";"PL;EL;FR;ES;DE;CH;UK;PT;IT";"/SCI;/EDU";1;0;0;1;0;0 88289;216011;MINILUBES;ONG;FP7-PEOPLE;PEOPLE-2007-1-1-ITN;FP7;Mechanisms of interactions in nano-scale of novel ionic lubricants with functional surfaces;2008-10-01;2012-09-30;;Recently, ionic liquids (IL) are employed as substitute for traditional solvents in catalysis, synthesis and electrochemistry. But little research work or actual applications have been published until now concerning the utilization of IL as lubricants. Generally, IL show no or very low vapour pressures, satisfying viscosity-temperature behaviour, no inflammability and high thermal stabilities up to 250°C. The choice of cation and anion as well as the design of side chains determine fundamental IL properties. These properties desirable for lubricants and the possibility to create tailor-made compounds give rise to the demand of in-depth investigations of IL in tribology. To our best knowledge, the project will be the first extensive and integral approach of IL towards potential future applications as lubricants for metals, ceramics and polymers as well as base for wear and friction reducing nanoparticles. The investigations will involve molecular design and synthesis of new IL as well as preparation of advanced materials containing or based on IL. Evaluation of lubricant and material performance will range from determination of physico-chemical properties including artificial aging of IL and mechanical testing (e.g. tensile and impact strength) to tribometrical experiments. Wear and friction properties will be completed by thorough surface characterization, in particular towards tribochemical reaction layers. Parameters gained from these experiments will be used for modelling of triboprocesses in nanoscale and for molecular design of new ionic lubricants. Studies on biodegradability, toxicology and economical aspects will be studied in detail, too, to verify legal requirements and opportunities for highly potential applications. The overall objective of this interdisciplinary and intersectorial approach is the generation of unique and comprehensive knowledge about IL on a sustainable basis for future implementations as high performance lubricants.;2719525;2719525;FP7-PEOPLE-2007-1-1-ITN;/MC-ITN;AC2T RESEARCH GMBH;AT;"INSTITUTUL DE CHIMIE MACROMOLECULARA PETRU PONI;MARTIN-LUTHER-UNIVERSITAET HALLE-WITTENBERG;FUNDACION TEKNIKER;UNIWERSYTET GDANSKI;GKN Sintermetals S.p.A.;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;UNIVERSIDAD DE VIGO;UNIVERZA V LJUBLJANI;CARDIFF UNIVERSITY";"RO;DE;ES;PL;IT;FR;SI;UK";"/EMP;/SOC;/EDU";1;0;0;1;0;0 100113;268322;FORMI 4-SEG;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-RG;FP7;Forbidden Minor Characterizations For 4-Searchable Graphs;2011-09-01;2014-08-31;;"Edge searching is a pursuit evasion game played on graphs. In the past two decades there has been fundamental work devoted to this topic by scientists in many diverse fields due to its highly interdisciplinary nature. We consider the problem of constructing a search plan in order to find a person lost in a system of caves which can be represented as a graph G. Equivalently, we aim to clean a network of tunnels filled with noxious gas using as few cleaners as possible. This minimum number for a graph G is the edge search number of G, and it is denoted as s(G). The problem has wide range of applications from network security to VLSI chip design. One of the major problems of edge searching is to characterize the graphs G such that s(G) is at most k, for a fixed positive integer k. This problem is solved only for k=1, 2 and 3 (Megiddo et. al. 1976). The problem has been considered as an open problem that has high priority. In this project our objective is to characterize those graphs for which k=4 searchers suffice and to generalize this characterization to any k>4. Our main contribution will be deriving a constructive characterization which works more efficient than the previous results. During the project we aim to improve the existing European interest on the subject and to start new discussions.";75000;75000;FP7-PEOPLE-2010-RG;/MC-IRG;KADIR HAS UNIVERSITESI;TR;;;/SCI;1;0;0;1;0;0 87764;218068;IMETI;ONG;FP7-PEOPLE;PEOPLE-2007-3-1-IAPP;FP7;Implementation of Membrane Technology to Industry;2008-06-01;2012-05-31;;The IMeTI proposal aims to create a programme of applied research for implementation of membrane technology into industry based on experience and knowledge transfer between Academia and Industry. New membranes with improved chemical stability in a wide range of solvents, and better controlled cutoff properties and commercially viable membranes with high selectivity and flux for gas separations will be developed. The overall scientific and technical aim of the IMeTI project is to make important paradigm shifts in organic solvent nanofiltration and high temperature gas separation/purification, using cutting edge technologies based on membranes. The project involves the integration of the invention of new membranes and applications in the University/ Research Institute Partners with the subsequent development of the necessary membrane technology up to processing scale by the SMEs. A key feature of this project will be the interdisciplinary nature of the Partners, and the fact that they bring inter-sectorial competence to the network. We aim to create widely applicable, scalable, high performance process techniques and technologies. The knowledge transfer and training programme involves Early Stage Researchers (ESR), at both university and industrial partners, each of whom gain high quality experience through combination of local and network wide research experience. Experienced Researchers (ER) will provide in depth knowledge, and will assist in mentoring the ESR. Visiting scientists will provide expertise from outside the network. In addition to their individual research, ESR and ER will increase their research capacity and knowledge through attendance of high level research conferences and workshops. IMeTI seeks to contribute to improving the European knowledge supply chain through this industry-academia programme of applied research aimed at developing engineers and scientists who are academically excellent and industrially experienced.;1806477;1806477;FP7-PEOPLE-2007-3-1-IAPP;/MC-IAPP;IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE;UK;"GVS S.P.A.;EVONIK MEMBRANE EXTRACTION TECHNOLOGY LIMITED;CEPAration BV;CHIMIKOTECHNOLOGITCHEN I METALURGITCHEN UNIVERSITET;CONSIGLIO NAZIONALE DELLE RICERCHE;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS";"IT;UK;NL;BG;FR";/EDU;1;0;0;1;0;0 91839;237834;COME-IN-CARE;ONG;FP7-PEOPLE;FP7-PEOPLE-IEF-2008;FP7;COmpound 21 and MElatonin in CArdiovascular REmodeling;2009-08-01;2011-01-31;;Cardiovascular (CV) diseases are the major source of morbidity and mortality in the EU with annual costs of € 169 billion. The control of hypertension and prevention of left ventricular (LV) hypertrophy and fibrosis, which could interrupt the CV continuum, still remain insufficient world-wide. A substantial part of current therapies modulate the renin-angiotensin system (RAS) and decrease the unfavorable stimulation of angiotensin type 1 receptors (AT1R). Results of the host group indicate that many of AT1R effects are opposed by type 2 receptor (AT2R) activation. AT2R are up-regulated in several pathologies, making targeting of AT2R effective specifically in disease. The investigation of long-term effects of direct AT2R activation on hypertension and CV remodeling was allowed only recently by the discovery of AT2R agonist, compound 21. Fellows results suggest, that the pineal hormone and antioxidant, melatonin, prevents fibrosis and can be especially useful in combination with RAS modulation. We aim to investigate the effects of 5-week administration of compound 21, melatonin and their combination in L-NAME hypertensive rats on CV remodeling and relevant protein expression pattern. Advanced, interdisciplinary techniques from physiology to molecular biology will be implemented. The findings should indicate whether the exciting AT2R targeting is a promising approach to CV diseases and whether the use of a novel drug combination can preserve myocardial structural homogeneity. This project will yield important scientific and clinical implications and provide an outstanding training, guaranteed by excellent researcher in charge. Proposed training will unfold researcher’s creativity, networking and other complementary skills and promote his scientific maturity and independence necessary to create an own research group. Possible reintegration of the researcher with his enhanced scientific output will increase the competitiveness in his country of origin.;;121598,2;FP7-PEOPLE-IEF-2008;/MC-IEF;CHARITE - UNIVERSITAETSMEDIZIN BERLIN;DE;;;"/SCI;/EMP";1;0;0;1;0;0 88153;200820;CARS EXPLORER;ONG;FP7-HEALTH;HEALTH-2007-1.2-2;FP7;Innovative contrast imaging by non-linear optics (NLO) for the observation of biological tissues in vivo and in real time, at cellular and molecular levels;2008-03-01;2011-08-31;;The CARS EXPLORER seeks to demonstrate the concept of innovative light-based contrasting technologies for functional in situ imaging in life science and biomedical research. Our ultimate goal is to develop an endoscope based on non-linear optics (NLO) and laser pulse phase shaping. Non linear laser pulse interactions with living tissues provide unique possibilities, such as an absence of sample preparation, direct multiparametric visualization with molecular specificity and cellular resolution, and deep sample penetration. Nevertheless, the effective transfer of NLO to biomedical applications faces major technological challenges related to the delivery of ultra-short laser pulses, the weakness of the signal produced in biological samples and the difficulty in interpreting generated contrasts. Therefore, the CARS EXPLORER interdisciplinary consortium includes partners with expertise ranging from optical physics to the clinic. The work plan is split into 5 RTD workpackages: three are intended to overcome specific technological problems with (1) the development of dedicated methodology using phase shaping for NLO imaging of deep biological tissues, (2) the development of specific photonic crystal fibre optics for the excitation, delivery and collection of NLO signals, and (3) the extraction of relevant information from NLO signals generated in biological tissues. The two other workpackages will determine the assets and constraints in NLO imaging through appropriate experimental biological models. These models will also assess each technological improvement made on the microscope and endoscope prototypes. Last, to bring the concept to the diagnostic level, we will explore the molecular and morphological NLO signatures associated with tumor development in skin cancer. In addition to the challenge of developing pulse shaped NLO-based endoscope technology, this project will have strategic and economic impact by providing a non-invasive functional exploration method.;4701881;3091129;FP7-HEALTH-2007-A;/CP-FP;INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE;FR;"UNIVERSITY OF BATH;MAUNA KEA TECHNOLOGIES;INSERM TRANSFERT SA;DE DUVE INSTITUTE;UNIVERSITAET STUTTGART;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS";"UK;FR;BE;DE";"/HCS;/MED";1;0;0;1;0;0 92693;234810;COMPLOIDS;ONG;FP7-PEOPLE;FP7-PEOPLE-ITN-2008;FP7;Physics of Complex Colloids: Equilibrium and Driven;2009-11-01;2013-10-31;;With progress in nanotechnology, biophysics, and polymer synthesis, colloidal science has reached a new level of importance. A large variety of complex colloids of different shapes, with binding specificity, and variable softness has been synthesized, opening quite exciting ways for engineering materials at the nanoscale. The purpose of COMPLOIDS is to obtain a fundamental understanding of the Physics governing the self-organization and the dynamical behavior of complex colloidal particles in the bulk, under confinement and out of equilibrium. For this purpose, the partners will consider a variety of novel, experimentally accessible colloidal systems that share the common properties of anisotropy, associativity and softness of their constituent particles. A well-coordinated combination of experiment, theory and simulation will explore the fundamental Physics, define similarities and differences between the systems considered and search for common underlying mechanisms of self-organization that are distinct to these complex and highly versatile colloidal systems. The technical objective of COMPLOIDS is to apply the gained knowledge with the goal of engineering novel materials in close collaboration with participating high-technology EU-companies. Young researchers will also profit from COMPLOIDS in a variety of ways. They will be exposed in high-level research working, within a highly connected and interdisciplinary team of researchers and developing state-of-the art tools in the Statistical Physics of Soft Matter. Further, they will attend world-rate graduate programs and courses in the participating academic partners and they will obtain hands-on experience of the industry sector through the participation of industrial partners.;4714765;4714765;FP7-PEOPLE-ITN-2008;/MC-ITN;UNIVERSITAT WIEN;AT;"TECHNISCHE UNIVERSITAET WIEN;THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;Rhodia Laboratoire du Futur;INSTITUT JOZEF STEFAN;SCHLUMBERGER CAMBRIDGE RESEARCH LIMITED;FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS;UNIVERSITAET STUTTGART;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;THE UNIVERSITY OF EDINBURGH;UNIVERSITA DEGLI STUDI DI ROMA LA SAPIENZA;UNIVERZA V LJUBLJANI";"AT;UK;FR;SI;EL;DE;IT";"/SCI;/EDU";1;0;0;1;0;0 99331;275201;Water-Spotcheck;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-IEF;FP7;Multi Sensor Fusion for Real-time Monitoring of Waste Water Quality;2012-01-03;2014-01-02;;The Water-Spotcheck interdisciplinary project will create new competence on the interface of engineering and biology at Liverpool on Merseyside. The water industry is one of the major industrial sector in the EU, threatened by erosion of world markets and slowing growth. Continued wealth creation requires a strong scientific base for training, new knowledge and innovation to support the sector. The interface of engineering and biology is an important key to technologies to improve the safety and the quality of water. The Water-Spotcheck project will take place in the context of development of multisensors fusion combining micro fabrication of polymer composite sensors, optical fibres and electromagnetic wave sensors operating at various frequencies ranging from 1kHz-100MHz to foster new and unique form of real time monitoring sensors. In wastewater treatment, recent legislation from the EU requires the removal of nutrients, such as phosphorous, ammonia and volatile fatty acids from wastewater before discharging to water courses. The measurements of these nutrients are mostly based on off-line monitoring and imply low frequency data sampling and delay between sampling and availability of the results. Hence, the Water-Spotcheck will provide the on-line monitoring to improve the daily process management, as well as facilitate the real-time detection of abnormal situations and the implementation of new control strategies. Evaluation of microbiocidal activity is essential to guide the sensor design and fundamental new knowledge in engineering and microbiology will also be discovered. The final stage of the project will use facilities at local waste water treatment plant by United Utilities to test the prototype demonstrator. A programme of written documentation, protocols, and projects with students, seminars and Open Days will ensure transfer of knowledge to staff and students at the Liverpool John Moores University.;270136,8;270136,8;FP7-PEOPLE-2010-IEF;/MC-IEF;LIVERPOOL JOHN MOORES UNIVERSITY;UK;;;"/EMP;/EDU;/NET";1;0;0;1;0;0 95976;252284;ICIEMSET;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IOF;FP7;Innovative Control, Identification and Estimation Methodologies for Sustainable Energy Technologies;2010-09-01;2013-08-31;;The aim of this project is to boost the knowledge, expertise and international contact-network of the young outgoing researcher in the field of systems and control, in order to foster his career and to support him in the development of stable, high-quality research and technology transfer activities at the return host, thus contributing to strengthen the research and development system at local, national and European levels. This aim will be pursued primarily via a structured three-years long program involving both theoretical and applicative, interdisciplinary research at the outgoing and return host organizations. Innovative robust control methodologies, able to cope with constrained, distributed and highly nonlinear processes, will be investigated during the two-years stay at the Center for Control, Dynamical systems and Computation of the University of California Santa Barbara, widely recognized as one of the world best research groups in this field. Such advanced control design techniques will be coupled with the innovative data-driven identification and estimation methods that the Complex Systems Modeling and Control group of Politecnico di Torino, the return host organization, has been investigating during the past 30 years, thus becoming a center of excellence in these topics. The expected theoretical outcome will be an organized set of methodologies that encompasses and links identification, estimation and control for complex uncertain systems. Among the numerous fields where such innovative techniques could be employed, the application to renewable and sustainable energy technologies will be pursued because of their actual critical importance, their relevance in the EU research roadmap and the personal interest of the researcher. In particular, the challenging problem of control of electric power grids that connect diverse kinds of generators and the breakthrough technology of high-altitude wind power using controlled airfoils will be deeply investigated.;247027,9;247027,9;FP7-PEOPLE-2009-IOF;/MC-IOF;EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH;CH;POLITECNICO DI TORINO;IT;"/LIF;/EDU";1;0;0;1;0;0 103997;319454;MC2020;ONG;FP7-PEOPLE;PEOPLE;FP7;"""""""Marie Curie Actions in Horizon 2020: regional and international impact""""""";2012-06-01;2013-01-31;;'The proposal describes the planning, management and implementation of a two days conference dedicated to Marie Actions in Cyprus, under the Cypriot Presidency of the Council in November 2012. The project is submitted in response to the 2012 Work programme and the aim of the conference is to take stock of the European research training potential, and the importance of international, interdisciplinary, and cross-sectoral cooperation, providing a suitable forum for discussing the future challenges of mobility actions under Horizon 2020.';201898;150000;FP7-Adhoc-2007-13;/CSA-SA;UNIVERSITY OF CYPRUS;CY;;;/EDU;1;0;0;1;0;0 90688;220251;C2CR;ONG;FP7-PEOPLE;PEOPLE-2007-2-1.IEF;FP7;High Energy Interactions: From Colliders to Cosmic Rays;2008-06-01;2010-05-31;;The years 2007 and 2008 will mark the completion of the Pierre Auger observatory and the start of the Large Hadron Collider (LHC) at CERN, respectively. Whereas the former has been built to uncover the sources of ultra-high energy cosmic rays, the latter is designed to test the Standard Model of particle physics. In both experiments, the use of Monte Carlo (MC) models to describe hadronic interactions is essential. In CR experiments, the measured properties of extensive air showers can be connected to the properties of the primary particle only via hadronic MC models. At present, the poorly known interaction models prevent a reliable determination of the primary type and its energy. Thus, an improvement of present day CR interaction models is an important and urgent task. This improvement will become possible soon, since the LHC experiments will deliver for the first time a experimental data in the kinematical region important for CR experiments. This projects aims to use these data to test and to develop further the existing QGSJET simulation. It is planed to include into QGSJET nonlinear interaction effects, to generalize the model to photo- nuclear interactions, and to account for higher twist QCD effects. Apart from its importance for a reliable extrapolation towards the very high CR energies, such a development will have an interdisciplinary aspect, opening the way for numerous applications in the collider physics. A self-consistent model like QGSJET that allows one to calculate within the same scheme total and diffractive cross sections, and to treat various hadronic final states, can be applied in collider experiments both for the general studies of hadronic interactions, and for more dedicated as, e.g., diffractive jet production. Thus the aim is to develop QGSJET to a truly universal simulation, able to describe collider data from LHC as well as to contribute to a more reliable determination of the primary type and its energy in UHECR experiments.;279239,42;279239,42;FP7-PEOPLE-2007-2-1-IEF;/MC-IEF;NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU;NO;;;"/SCI;/EDU";1;0;0;1;0;0 87291;220150;PEPINEN;ONG;FP7-PEOPLE;PEOPLE-2007-2-1.IEF;FP7;Processing and Electron Probing Inorganic Nanostructures for Emerging Nanotechnologies;2008-03-17;2009-03-16;;Since their discovery carbon nanotubes have generated huge interest due to their one-dimensional nature and their unique physical properties. However, a number of serious obstacles stand in the way of using them as useful functional nanomaterials. They are in fact poorly dispersable in common solvents and generally produced in a wide range of electronic types, with separation by type proving difficult. In view of these issues attention is now moving towards inorganic alternatives. In this context nanowires made up of molybdenum, sulfur and iodine (MoSI) and WS2 nanotubes have been shown to be within the most promising. Easy fabrication readily scaled up for a range of compounds, uniformity in diameters and electronic type and functional properties very similar to carbon nanotubes are among their most important qualities. However, being new class of materials, they are yet to be extensively studied. A complete understanding indeed is crucially required for further exploitation in the numerous technological applications they have been proposed for. The project aims to address crucial problems such as dispersability, processability and manipulation of these objects. Finding the optimal dispersion conditions will powerfully bring these materials on the technological and applicative scene. Once unlocked the solution processing issues other innovative and intriguing aspects will be covered, using the most advanced electron microscopy technologies to intimately understand the role of punctual structural defects in the ultimate physical properties of the materials. Correlation between physical properties and structural modifications will be for the first time established. The success of this proposal will give an important and unique contribute to the field, leading to technological innovations, community relevance and to a significant launch of the researcher, Dr. V. Nicolosi, in her first appointment in an advanced career at interdisciplinary level.;168256,91;168256,91;FP7-PEOPLE-2007-2-1-IEF;/MC-IEF;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;UK;;;"/SCI;/EDU";1;0;0;1;0;0 88063;221543;INNATE;ONG;FP7-PEOPLE;PEOPLE-2007-2-1.IEF;FP7;Integrated Nanocrystal Tunnelling for Molecular Electronics;2008-04-01;2010-03-31;;The INNATE project focuses on noble metal nanocrystals in the quantum confinement size range as active elements in molecular electronic circuits. Supported by a successful proof-of-concept experiment, multistate switch and transistor function for these systems will be demonstrated, unparalleled in conventional electronics. This novel electronic function will be integrated with that of tailored redox molecules both in a vertical Scanning Probe Microscopy configuration and in a nanogap electrode set-up to form nanoelectronic circuits, thus bridging top-down and bottom-up approaches. Our strategy focuses on electrolyte gating at electrified solid/liquid interfaces, which can address physical gates down to 1 nm by achieving strong electronic coupling, and allows the target “device” to function under ambient conditions. In addition to its ambitious technical goals, the INNATE project will substantially contribute to prospects of professional maturity and independence of the applicant by adding crucial scientific competencies in the highly interdisciplinary area of nanoscale electrochemistry and molecular electronics, thus developing his research niche of organic–inorganic hybrid nanostructures towards a high-level molecular understanding of structure–functionality–reactivity relations. Research training objectives focus on advanced scanning probe and nanogap electrode techniques, together with complementary training in research management, high-level dissemination and networking activities, including links to industry. Fully integrated in the European Research Area, the project will significantly enhance visibility and attractiveness of European science and technology.;246177,73;246177,73;FP7-PEOPLE-2007-2-1-IEF;/MC-IEF;UNIVERSITAET BERN;CH;;;"/SCI;/EDU";1;0;0;1;0;0 89413;230886;AUTOMOTIVE INDUSTRY;ONG;FP7-PEOPLE;FP7-PEOPLE-IRG-2008;FP7;Industrial upgrading and regional development effects of the Czech and Slovak automotive industries;2008-11-03;2012-11-02;;"The proposed project aims to study the effects of automotive foreign direct investment (FDI) on industrial upgrading and regional economic development in the Czech Republic and Slovakia. The research project is designed to deliver policy recommendations contributing to the effective implementation of the EU Cohesion and Regional Policies; and allows the principal investigator to develop a personal network for future international research collaboration dealing with the effects of FDI, the automotive industry and regional development in the context of the EU. The knowledge will be transferred to the host institution, Charles University in Prague, in the form of teaching, training and supervising both pre- and post-doctoral students. As the automotive industry has become a leading industrial sector in both countries, the research project studies its effects on national and regional economic development. The research particularly focuses upon the evaluation of FDI effects on industrial upgrading, development of supply linkages with local small and medium sized enterprises, and the transfer of knowledge from foreign-owned to domestic companies. The research project also aims to evaluate regional assets and advantages for the automotive industry and to what extent they fit the strategic needs of transnational corporations. The project uses an interdisciplinary approach as it draws on research traditions in three different disciplines: research on regional development and production networks in economic geography, research on FDI, automotive industry and spillover effects in economics, and research on global value chains and economic embeddedness in industrial sociology. The financial support to the proposed project will allow the re-integration of the highly experienced US-based researcher back to his home institution in the Czech Republic and thus will further support the competitiveness and attractiveness of the European Research Area.";100000;100000;FP7-PEOPLE-IRG-2008;/MC-IRG;UNIVERZITA KARLOVA;CZ;;;"/SCI;/EMP;/COO";1;0;0;1;0;0 87669;213238;RAINBOW;ONG;FP7-PEOPLE;PEOPLE-2007-1-1-ITN;FP7;High quality Material and intrinsic Properties of InN and indium rich Nitride Alloys - (The RAINBOW ITN);2008-10-01;2012-09-30;;Indium nitride is a new narrow gap semiconductor (<0.7 eV), which alloys with GaN (3.5 eV) and AlN (6.2 eV) will allow the spectral range from telecom to hard UV wavelengths to be covered. This narrow band gap makes InN an exciting material from which to develop highest efficiency solar cells. Moreover, due to an electron mobility of around 4000 cm2/Vs and very high saturation velocities, InN is an ideal material for the development of high electron mobility devices capable of operating in the Terahertz range. To ensure the production of reliable commercial devices, rigorous fundamental research is required to understand the layer growth mechanisms and optimize material properties. In RAINBOW, academic and industrial consortium, the theoretical work will encompass modelling of the atomic structure and properties of the material from empirical potentials to ab initio techniques. Experiments will provide correlated structural, electronic, optical and chemical information from the nano to the macroscopic scale. In a closely concerted effort, we will determine the best conditions for the growth of highest quality InN and In rich (In,Ga,Al)N alloys by the main growth techniques (MOVPE, PAMBE,HVPE ). Under the supervision of world leading experts, numerous young researchers will directly benefit from this interdisciplinary and multisectorial research and training effort. The young researchers involved in this programme will also learn to manage research and industrial projects.;4778667;4778667;FP7-PEOPLE-2007-1-1-ITN;/MC-ITN;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FR;"OTTO-VON-GUERICKE-UNIVERSITAET MAGDEBURG;AALTO-KORKEAKOULUSAATIO;ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE;TECHNISCHE UNIVERSITAET BERLIN;FRIEDRICH-SCHILLER-UNIVERSITAT JENA;TECHNISCHE UNIVERSITAET ILMENAU;ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA;THE UNIVERSITY OF WARWICK;III-V LAB;INSTYTUT FIZYKI POLSKIEJ AKADEMII NAUK;UNIVERSIDAD POLITECNICA DE MADRID;AIXTRON AG;UNIVERSITY OF STRATHCLYDE";"DE;FI;CH;IT;UK;FR;PL;ES";"/EMP;/SOC;/EDU";1;0;0;1;0;0 88474;212214;CESSDA-PPP;ONG;FP7-INFRASTRUCTURES;INFRA-2007-2.2-01;FP7;PREPARATORY PHASE PROJECT FOR A MAJOR UPGRADE OF THE COUNCIL OF EUROPEAN SOCIAL SCIENCE DATA ARCHIVES (CESSDA) RESEARCH INFRASTRUCTURE;2008-01-01;2010-06-30;;"This proposal for a major upgrade to the CESSDA Research Infrastructure is a response to the general principles and vision set out in the 2004 Blueprint for the European Research Obsrvatory for the Humanities and Social Science and will meet the goals set out in that report to ‘strengthen interdisciplinary and cross-border collaboration and comparative research on a European dimension… enhance the building of research infrastructure capacity in the less resourced European countries of today [and]… it will increase the opportunity to improve knowledge on social processes and thus holds great potential in terms of advising European and national policy-makers on how to manage the challenges currently faced by the societies of Europe.’ Building on the existing operational structure of the Council of European Social Science Data Archives (CESSDA) network of data archives and its associated partners, this proposal for a major RI upgrade will seek to address the major gaps and deficiencies identified by the EROHS report on Research Infrastructures through the facilitation of access to and sharing of existing European and national data; the development of improved standards and documentation, and by enabling the linking of cross-national data and the generation of new and genuinely European data for the comparative researcher. Data are the single most important component necessary for a science based understanding of society and to promote and facilitate access to data is to promote research. Although there have been significant advances in recent years in making data available for scientific use, these advances have not bee European-wide. There still remains a large difference in both the actual availability of data as well as in the value that is attached to accessing data across Europe. This proposal will directly address these differences as a precursor to the implementation of an enhanced CESSDA Infrastructure.";4164974,28;2675250,94;FP7-INFRASTRUCTURES-2007-1;/CP-CSA-Infra;UNIVERSITY OF ESSEX;UK;"FONDATION SUISSE POUR LA RECHERCHE EN SCIENCES SOCIALES;GESIS-LEIBNIZ-INSTITUT FUR SOZIALWISSENSCHAFTEN EV;UNIVERSITATEA DIN BUCURESTI;STATENS ARKIVER;KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW;TARKI TARSADALOMKUTATASI INFORMATIKA EGYESULES;TAMPEREEN YLIOPISTO;NORSK SAMFUNNSVITENSKAPELIG DATATJENESTE AS;INSTITUTE OF SOCIOLOGY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC PUBLIC RESEARCH INSTITUTION;UNIVERSITA' DEGLI STUDI DI MILANO-BICOCCA;WIENER INSTITUT FUR SOCIALWISSENSCHAFTLICHE DOKUMENTATION UND METHODIK;ETHNIKO KENTRO KOINONIKON EREVNON;CENTRO DE INVESTIGACIONES SOCIOLOGICAS;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;GOETEBORGS UNIVERSITET;UNIVERZA V LJUBLJANI";"CH;DE;RO;DK;NL;HU;FI;NO;CZ;IT;AT;EL;ES;FR;SE;SI";/SCI;1;0;0;1;0;0 88791;231063;NAGOYA2BCN;ONG;FP7-PEOPLE;PEOPLE-2007-4-3.IRG;FP7;Characterization of membrane protein dynamics by hydrogen/deuterium exchange and time-resolved infrared spectroscopy, assisted by maximum entropy and Bayesian methods of analysis;2008-09-01;2010-08-31;;Protein dynamics is essentially linked to protein function, aggregation, and folding. Time-resolved spectroscopy is specially suited to reveal these dynamics, counterbalancing the static pure-structural information provided by X-ray crystallographic structures. In equilibrium, protein conformation fluctuates, eventually visiting all possible higher-energy states in equilibrium with the ground state conformation. For soluble proteins the dynamics of such fluctuations have been successfully detected and characterized by hydrogen/deuterium exchange (HDX) combined with NMR spectroscopy. However, experimental limitations of NMR spectroscopy have precluded a similar level of understanding of the dynamics of membrane proteins. Proteins dynamics manifest themselves also when a fast perturbation is applied, such as when a laser pulse is applied to proteins with photocycles. Both in HDX and in perturbation experiments the time-resolved response of the system is a multi-exponential relaxation process. However, the relevant information to characterize and understand the protein dynamics is not the relaxation process itself, but the number, value, and nature (discrete/distributed) of the rate constants of the relaxation process. In this project our first goal is the improvement, development and application of maximum entropy and Bayesian methods to analyze the multi-exponential data arising in the HDX of membrane proteins, and in the photocycles of membrane proteins. Simultaneously, we will implement new experimental approaches of HDX to obtain dynamics information of membrane proteins by infrared spectroscopy, and apply them to at least three membrane protein systems: the melibiose transporter, bacteriorhodopsin, and a G-protein coupled receptor chimera. The combined success of both interdisciplinary goals should provide unique and fundamental information for a better understanding of membrane protein dynamics.;50000;50000;FP7-PEOPLE-IRG-2008;/MC-IRG;UNIVERSITAT AUTONOMA DE BARCELONA;ES;;;"/SCI;/COO";1;0;0;1;0;0 89797;219667;FISHINUTRIGEN;ONG;FP7-PEOPLE;PEOPLE-2007-2-1.IEF;FP7;Fish intestinal nutrigenomics in response to fish oil replacement in Atlantic salmon diets;2008-07-10;2010-07-09;;There is an urgent need to replace fish oil (FO) and meal in aquaculture diets with sustainable alternatives, vegetable oils (VO) being the primary candidates. However, growth of fish on VO results in lower levels of n-3HUFA in their flesh, compromising their nutritional value to the human consumer. There is therefore a pressing need to identify strains of fish with reduced requirements for pre-formed dietary n-3HUFA. The intestine is the gateway of nutrients into the body and the enterocyte intracellular metabolic activity is much more important than initially thought. However, very little information exists on how the physiological functions of the intestine are affected by different dietary lipids. Additionally, the inclusion of VO in the diet of carnivorous fish commonly results in histological changes in the intestine. Identification of the genes and pathways involved in PUFA metabolism in salmon intestinal tissue is of direct relevance to these problems. This project will address this issue by the identification of salmon genes and metabolic pathways in intestinal tissue influencing traits that are important in terms of sustainability of farm production and nutritional quality for the consumer. The project will apply cutting edge molecular techniques for the analyses of fish transcriptomes (microarrays) and proteomes (proteomics), to determine differential expression patterns in intestine of salmon fed FO and VO and how they may be affected by genotype (fatty or lean families). Bioinformatic analyses will enable key pathways, genes and enzymes/proteins to be identified. The project is a groundbreaking example of an interdisciplinary approach combining traditional nutritional and biochemical studies with modern molecular analyses to address a problem which is not only of scientific interest but also of critical importance to the future development and continuing expansion of aquaculture and the delivery of safe and nutritious seafood for the people of the EU.;169957,94;169957,94;FP7-PEOPLE-2007-2-1-IEF;/MC-IEF;THE UNIVERSITY OF STIRLING;UK;;;"/SCI;/EDU";1;0;0;1;0;0 88131;220999;INEST;ONG;FP7-PEOPLE;PEOPLE-2007-2-1.IEF;FP7;Intuitive Ethics and Sensitive Technologies;2008-10-01;2010-10-31;;The broad objective of the Intuitive Ethics and Sensitive Technologies (INEST) project is to advance the understanding of factors underlying public perceptions of sensitive technologies – technologies whose implications intersect with social values and challenge presumptions about the natural order and life. It is intended to move the field beyond static descriptions of public opinion to the dynamics of intuitive (public) ethics, characterised by social values, moral dilemmas and competing world views. An interdisciplinary framework will be developed integrating findings from studies of technology perception with theories and concepts from moral psychology, social psychology, anthropology and sociology. This framework will guide a programme of empirical research that includes quantitative and qualitative analyses of intuitive ethics and a case study on synthetic biology. While it is assumed that every technology has some unique characteristics, it is also assumed that in the public mind there a ‘family resemblances’ between different technologies. Some such family resemblances are the result of challenges to widely accepted notions of the natural order and life, raising similar ethical concerns among the public – concerns that extend beyond utilities and risks. The research will identify the dimensions of sensitivity and explore their mutual interactions and conflicts. This will provide a better theoretical understanding of public perceptions of technologies, tools for the early identification of potentially controversial technologies and support for devising agendas for public engagement.;170142,1;170142,1;FP7-PEOPLE-2007-2-1-IEF;/MC-IEF;LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE;UK;;;"/SCI;/EDU";1;0;0;1;0;0 87988;219834;TBX5-NKX2;ONG;FP7-PEOPLE;PEOPLE-2007-2-1.IEF;FP7;Crystallographic and biochemical studies of the human TBX5-Nkx2-5-DNA complex;2009-01-01;2010-12-31;;Holt Oram syndrome (HOS) is a heart and limb syndrome, which manifests itself in 1 of 100000 live births. HOS syndrome is an autosomal-dominant disease, where forelimb and cardiac congenital abnormalities are observed. The syndrome is connected to mutations in the T-box transcription factor TBX5 gene. Similar symptoms are observed when mutations in the homeobox transcription factor human Nkx2-5 are present. TBX5 and Nkx2-5 interact with each other and synergistically activate the promoters of the cardiac-specific natriuretic peptide precursor type A (ANF) and connexin (cx40). The project goal is the biochemical characterization and crystal structure solution of the ternary TBX5-Nkx2-5-DNA complex. The crystal structure of the ternary complex will allow a comprehensive structural analysis of the interaction mechanism between TBX5 and Nkx2-5 and their DNA binding sites and will elucidate the synergistic promoter activation of TBX5 and Nkx2-5 on a molecular level. Such insight is of broad interest for cardiovascular biologist because it opens the ultimate perspective to use this knowledge for influencing cardiac growth and for cardiac regeneration. The results of this project will contribute to the European quality and competitiveness in cardio vascular research. The project uses the full portfolio of structural biological research and requires interdisciplinary knowledge in molecular biology, biochemistry, biophysics, protein crystallography and bioinformatical techniques. Thus, the researcher has the possibility to gain skills in all techniques necessary for doing successful research in structural biology. In addition, the multidisciplinary environment at the EMBL will give the researcher the possibility to interact and communicate with scientists in fields other than crystallography. All mentioned points will allow the scientist to gain professional maturity and to develop an independent research career.;158127,84;158127,84;FP7-PEOPLE-2007-2-1-IEF;/MC-IEF;EUROPEAN MOLECULAR BIOLOGY LABORATORY;DE;;;"/SCI;/EDU";1;0;0;1;0;0 90991;237876;BIOSEC;ONG;FP7-PEOPLE;FP7-PEOPLE-IOF-2008;FP7;BIOSEC: Security and Privacy in Life Sciences Data;2009-03-01;2012-02-29;;"Nowadays, there are over a thousand different life science databases with hundreds of gigabytes of content ranging from gene-property data for different organisms to brain image data. Such databases are distributed over the web and have high degrees of heterogeneity and different levels of quality. Research in life sciences requires the combination of various sources of data and processing by bioinformatics tools deployed on powerful and efficient platforms for patterns, similarities, and unusual occurrences to be observed. Therefore, sharing of data among institutions and researchers is essential for life sciences. However, this gives rise to many security and privacy issues that need to be addressed at the lowest level, that of data. This project has an interdisciplinary nature lying in the intersection of life sciences and data management. The common denominator is data and we use a security lens to observe them. The objectives of the project can be summarized as: (i) the critical review of state-of-the-art techniques for ensuring security and privacy in databases; (ii) the study of the data management requirements for life sciences applications; (iii) the analysis of security and privacy threats for life sciences; (iv) the proposal of novel, or the extension of existing, techniques for addressing all issues discovered; and (v) the application in real world applications. It is the scope of this project to provide methods for ensuring privacy and security custom-tailored to real-world life sciences applications. To achieve this, competence in both life sciences applications as well as data security and privacy methods must be attained. Upon conclusion of the project, the applicant will have acquired sufficient expertise in order to: (i) disseminate knowledge about the security and privacy implications to life sciences researchers; and (ii) provide with real-world case studies and detailed security and privacy requirements to data management researchers.";214655,36;214655,36;FP7-PEOPLE-IOF-2008;/MC-IOF;ATHINA-EREVNITIKO KENTRO KAINOTOMIAS STIS TECHNOLOGIES TIS PLIROFORIAS, TON EPIKOINONION KAI TIS GNOSIS;EL;;;"/COO;/EDU";1;0;0;1;0;0 87992;219944;GEOPAL;ONG;FP7-PEOPLE;PEOPLE-2007-4-1.IOF;FP7;GEOARCHAEOLOGY, PALEOENVIRONMENTS AND LUMINESCENCE GEOCHRONOLOGY IN THE EASTERN ALPINE REALM AND SOUTH AFRICA DURING THE LAST GLACIAL CYCLE (115-11 ka);2008-09-01;2011-10-31;;"The last glacial cycle included some of the coldest and most unstable moments of the last 2 million years of Earth history. Climate-driven environmental changes impacted on the landscape and also influenced human evolution, dispersal and culture; they may also have played a role in the extinction of the Neanderthals. Human/environment relations thus merit detailed research. Accurate chronologies for human activities and contemporaneous paleoenvironmental records are key requirements to sustain further progress in geoarchaeology and to improve our knowledge of the history of humankind. Optically stimulated luminescence (OSL) dating is currently one of the most dynamic fields in geochronology. The single-grain approach, in particular, opens up new opportunities for dating materials that have hitherto been ignored. Pioneering work has shown that archaeological sequences in cave-mouth deposits can be reliably dated using single sand-sized grains of quartz. The overseas host institution (U. Wollongong, Australia) is a world-renowned geochronology laboratory with recognised expertise in single-grain OSL dating. The applicant will join this group in an international and interdisciplinary project to examine the origin of modern human behaviour and the role of paleoenvironmental changes in landscape and human evolution in South Africa. A carefully designed research agenda will enable single-grain OSL dating to be applied to selected archaeological sites and related paleoenvironmental records in the eastern alpine realm as part of the follow-up phase. We will develop high-precision OSL chronologies for archaeological and loess sequences, and match these to the paleoclimatic record of U-Th dated alpine speleothems. The improved chronological control will greatly assist archaeological interpretations of when and how past environmental changes impacted on human societies.";237050,23;237050,23;FP7-PEOPLE-2007-4-1-IOF;/MC-IOF;UNIVERSITAET INNSBRUCK;AT;;;"/SCI;/COO";1;0;0;1;0;0 103498;302919;POGS;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IEF;FP7;Polymer Grating Sensors;2012-05-01;2014-04-30;;"'“POlymer Grating Sensors” (POGS) is a project that will significantly extend the range of application of silica optical fibre grating sensors by developing a mature version of the technology in polymer optical fibres, whilst at the same time forming a training environment for the fellow that is both interdisciplinary and intersectoral. Polymer fibres offer some significant potential advantages over silica, the two most important perhaps being the ability to sense much higher strains – as may be encountered in modern composite materials - and the considerably reduced stiffness of the plastic compared to the glass fibre. Polymers are however complex materials and the properties of a polymer grating sensor are dependent on the sensor fabrication process. This project places the fellow at the centre of a collaboration between two key groups in this field. The host, Dr. DJ Webb, heads a team who are the world leaders in polymer fibre grating fabrication. The fellow will also spend several months at the Technical University of Denmark, who are at the forefront of microstructured polymer fibre fabrication particularly relating to fibres based on TOPAS cyclic olefin copolymer. In 2011 this collaboration produced the first grating sensors in TOPAS fibre and have shown that these devices do not display the sensitivity to humidity that is a problem with the usual fibres based on poly(methyl methacrylate). This timely project gives the fellow the opportunity to explore and develop this brand new fibre technology for long term, high strain sensing, producing optimised, repeatable and reliable grating sensors and develop new applications whilst undertaking research with industrial collaborators (Dr. Peter Foote - BAe Systems, Dr. Kate Sugden – Astasense Ltd) who will provide an industrial perspective on the technology. The project incorporates both “on the job” and formal training in both scientific and “soft” skills to allow the fellow to develop as an independent researcher.'";200371,8;200371,8;FP7-PEOPLE-2011-IEF;/MC-IEF;ASTON UNIVERSITY;UK;;;/SCI;1;0;0;1;0;0 95039;256580;MONINTERFLUOPROT;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-RG;FP7;Monitoring of cell signaling pathways via interaction of fluorescently tagged proteins;2010-06-01;2013-05-31;;At present, fundamental questions in biomedical translational research require the use of non invasive nanometer resolution techniques that facilitate the study of cell structure and function in vivo. The proposed project is highly interdisciplinary: it encompasses advanced research techniques in biophysics, cell physiology, and molecular biology. The long term aim of the project is to establish a cutting-edge multidisciplinary program in biomedical and translational research at the Department of Biophysics at the P.J. Šafárik University in Košice, Slovakia. The foundation of this program is laid out within EU structural fund projects CEVA I and II and SEPO I and II. The applicant, Dr. Stroffekova has advanced knowledge of cell physiology and biophysics, and was therefore approached to participate in the design and planning of the infrastructure for above mentioned EU projects, and to carry on her further research at the Department of Biophysics. The specific objectives of the present project are to introduce new research methodologies that will be used within infrastructure and to expand the scientific potential at the Department of Biophysics. Specifically, the project will introduce and establish electrophysiological measurements by whole cell patch clamp, site-directed mutagenesis and creation of fluorescent fusion proteins (FFPs) for application in confocal microscopy and fluorescence resonance energy transfer (FRET) measurements, and immunocytochemistry. All these methodologies will be used in novel approach to quantify the onset and modulation of apoptosis by FFPs, which will expand research capabilities for a molecule targeted photodynamic therapy in malignant cells. The proposed project and its funding will greatly improve applicant’s abilities to establish a continuation and transfer of her research from USA to Slovakia, to introduce proposed methodologies in the Department of Biophysics, and to firmly anchor her long term career in Slovakia.;75000;75000;FP7-PEOPLE-2009-RG;/MC-IRG;UNIVERZITA PAVLA JOZEFA SAFARIKA V KOSICIACH;SK;;;/SCI;1;0;0;1;0;0 94071;242203;ECHOUTCOME;ONG;FP7-HEALTH;HEALTH-2009-3.2-2;FP7;European Consortium in Healthcare Outcomes and cost-benefit research;2010-02-01;2013-01-31;;ECHOUTCOME is an interdisciplinary European research platform with the aim of assessing methodological properties of Healthcare Outcome and Cost-Benefit studies. The ECHOUTCOME consortium is composed by eight partners from 4 countries including three academic international experts in Outcome Research from, the French Scientific Society in Health Economics, the European office of one Multinational BioPharma industry, two research organisations (SME) specialized in advanced statistics and modelling and one organization specialized in international research administration. The general objective of this consortium is to study European health systems in order to assess decision making criteria in the frame of national needs and expectations across member states concerning healthcare outcomes and cost-benefit analyses Using both the descriptive and the experimental approaches, the ECHOUTCOME consortium will be able to investigate the relationship between quality of care with costs, efficiency and accessibility by indentifying and assessing existing approaches, but with the capability to develop new approaches for Decision Making purpose. Considering the fact that some Health agencies in Europe such as the National Institute of Clinical Excellence in the UK has published a guidance recommending one specific outcome (Quality Adjusted Life Years) and one specific Cost Benefit approach (Cost per Quality Adjusted Life Years) as a requirement for population access to innovative health technologies, it is urgent that the European Union considers the properties and consequences to use one reference case, before spreading or recommending any specific approach in other member states. ECHOUTCOME will allow to make major advancements to improve the knowledge about Health Systems organizations and expectations, existing Health Outcomes and Cost-Benefit approaches and to develop new approaches for Health decision making.;1386984,2;1064143;FP7-HEALTH-2009-single-stage;/CP-FP;UNIVERSITE LYON 1 CLAUDE BERNARD;FR;"LYON INGENIERIE PROJETS;DATA MINING INTERNATIONAL SA;Société Française d'Economie de la Santé;UNIVERSITA COMMERCIALE LUIGI BOCCONI;UNIVERSITE LIBRE DE BRUXELLES;CYKLAD GROUP SAS;BRISTOL-MYERS SQUIBB COMPANY CORP";"FR;CH;IT;BE;US";"/ECO;/HCS";1;0;0;1;0;0 95437;253942;AMPT;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IEF;FP7;Ancient Maritime Pitch and Tar: a multi-disciplinary study of sources, technology and preservation;2010-10-05;2012-10-04;;This intra-European fellowship places the designated researcher at the hub of a collaborative interdisciplinary project combining chemistry, archaeology, maritime history and conservation to advance understanding of the technology and use of pitch/tar products in Medieval Europe and to evaluate their stability in archaeological and museum environments. Analytical chemistry techniques will be used to research the sources and technology of pitch/tar from a number of medieval shipwrecks. Material from the recently excavated Newport Ship will be a focus for the study. This unique assemblage offers scope for the investigation of ship building techniques and repair strategies alongside examination of differential preservation due to burial environment. Interpretation of the Newport material will be supported by co-investigation of pitch/tar from at least four further wreck sites with differing preservation conditions enabling the impact of both intra and inter-site variability in burial environment to be compared. Production and ageing of pitch/tar materials under laboratory conditions will aid interpretation of the archaeological material and allow the stability of the materials in different environments to be systematically evaluated. This research will provide vital knowledge for improving approaches to the care of pitch/tar materials in museum collections. The researcher’s background in resin chemistry and previous experience of maritime archaeological material provide an excellent match for the project’s skill and knowledge requirements while offering plenty of scope for the acquisition of new competencies and broadening of experience. The host organisation offers a completely new form of working environment for the researcher and a multitude of opportunities for forging of professional contacts and relationships. It also offers the potential for wide dissemination of the research maximising opportunities for international transfer of knowledge generated.;171740,8;171740,8;FP7-PEOPLE-2009-IEF;/MC-IEF;BRITISH MUSEUM;UK;;;"/SCI;/EDU;/ITT";1;0;0;1;0;0 99643;263924;NET4SOCIETY2;ONG;FP7-SSH;SSH.2010.8-1;FP7;Trans-national co-operation among National Contact Points for Socio-economic sciences and the Humanities (SSH NCPs);2011-02-01;2013-01-31;http://www.net4society.eu/;"'A strong and efficient Network of National Contact Points (NCPs) is not only elementary to the success of the Socioeconomic Sciences and the Humanities (SSH) Programme of the 7th EU Framework Programme but also to the realization of the European Research Area. The trans-national SSH NCP cooperation project NET4SOCIETY? strives to increase the awareness for and the visibility of the SSH Programme and its “new approach” while endorsing a strong NCP network dedicated to increasing the professionalism of its members. NET4SOCIETY? strengthens and enhances the existing SSH NCPs´ network NET4SOCIETY. NET4SOCIETY? offers web-based tools for easing SSH NCP work, specific high quality training sessions, expert exchanges and dedicated workshops. NET4SOCIETY? organizes large international SSH events to promote the relevance of SSH research in Europe and the FP7 SSH Programme. To support the specifications of the “new approach” these large events include interdisciplinary brokerage events. The project provides a dedicated SSH Research Directory for the specific area of Socioeconomics and the Humanities, and a refined partner-search support system. These tools will be published on the project’s dedicated Internet site. NET4SOCIETY? continues the work of the 2008-2011 SSH network NET4SOCIETY. The Network consists of a total of 60 NCPs representing 53 countries, including NCPs from International Cooperation Partner Countries (ICPCs). NET4SOCIETY? is open to all SSH-NCPs. A core group of Work Packages leaders, including the Third Country Contact Points, works closely together with the co-ordinator to implement the project’s objectives. All SSH NCPs are invited to be involved either as 'beneficiary' or as third parties ('national expert') and are thus entitled to access all network events and tools and share in the network's pool of information.'";2221550,4;1799739;FP7-SSH-2010-4;/CSA-SA;Deutsches Zentrum fur Luftund Raumfahrte.V;DE;"RANNSOKNAMIDSTOD ISLANDS;SDRUZHENIE ASOCIACIYA IKONOMIKAI DEMOKRACIYA;STARPTAUTISKA LIETISKAS OPTIKAS BIEDRIBA;BELARUSIAN STATE UNIVERSITY;IDRYMA PROOTHISIS EREVNAS;AGENZIA PER LA PROMOZIONE DELLA RICERCA EUROPEA;TURKIYE BILIMSEL VE TEKNOLOJIK ARASTIRMA KURUMU;AUTORITATEA NATIONALA PENTRU CERCETARE STIINTIFICA;Ministerul Educatiei Nationale si Cercetarii Stiintifice;INSTYTUT PODSTAWOWYCH PROBLEMOW TECHNIKI POLSKIEJ AKADEMII NAUK;MATIMOP, ISRAELI INDUSTRY CENTER FOR RESEARCH & DEVELOPMENT;NORGES FORSKNINGSRAD;GOVERNMENT INSTITUTION CENTRE FOR SCIENCE RESEARCH AND STATISTICS;AN TUDARAS UM ARD OIDEACHAS;OFFICE OF THE PRIME MINISTER;Irish Research Council for the Humanities and Social Sciences;VEREIN EURESEARCH;ETHNIKO IDRYMA EREVNON;OESTERREICHISCHE FORSCHUNGSFOERDERUNGSGESELLSCHAFT MBH";"IS;BG;LV;BY;CY;IT;TR;RO;PL;IL;NO;RU;IE;MT;CH;EL;AT";"/SOC;/NET";1;0;0;1;0;0 96884;264780;METAFLUX;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-ITN;FP7;Metabolic Flux Analysis and Cancer;2010-11-01;2014-10-31;;"The post-genomic era has been driven by the development of technologies that allow the function of cells and whole organisms to be explored at a molecular level. Metabolomics is concerned with the measurement of global sets of low-molecular-weight metabolites, which represent important indicators of physiological or pathological states of organisms. Such profiles provide a more comprehensive view of cellular control mechanisms in man and animals, and raise the possibility of identifying surrogate markers of disease. Metabolomic approaches use analytical different techniques to measure populations of low-molecular-weight metabolites in biological samples. To decipher large metabolic data sets advanced statistical and bioinformatic tools are commonly employed. Although metabolomics has only recently emerged, dynamic profiles generated in Metabolic Flux Analysis (MFA) are becoming increasingly important to analyse biological networks in a quantitative manner and as part of systems biology approaches. MFA allows us to probe hypotheses by incorporating a priori biological knowledge to provide practical descriptions of observed cell behaviours, and to characterise the outcome of network perturbations. Flux analysis is of particular value for the diagnosis, differentiation and elucidation of mechanisms in cancer. This was recognised as early as 1924 by the Nobel Prize winner Otto Warburg who attributed cancer to a change in cellular energy production. This theme has experienced a revival in recent years through research, which has established mitochondrial dysfunction as a major mechanism in cancer. This proposal seeks funding for a truly interdisciplinary European consortium to train researchers to exploit the gains of new technologies provided by metabolic flux analysis in the context of cancer with a mixed focus on new developments and applied end-points.";4384122,96;4384122,96;FP7-PEOPLE-2010-ITN;/MC-ITN;THE UNIVERSITY OF BIRMINGHAM;UK;"THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;WEIZMANN INSTITUTE OF SCIENCE;ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE;MAGYAR TUDOMANYOS AKADEMIA SZEGEDIBIOLOGIAI KUTATOKOZPONT;UNIVERSITAT DE BARCELONA;TEL AVIV UNIVERSITY;OXFORD INSTRUMENTS MOLECULAR BIOTOOLS LIMITED;BIOCRATES LIFE SCIENCES AG";"UK;IL;CH;HU;ES;AT";"/EDU;/NET";1;0;0;1;0;0 98234;273418;SOLiCOAPs;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-IEF;FP7;Self-Organising Liquid-Crystalline OligoAnilines for Photovoltaic Applications;2011-05-03;2013-05-02;;"Major interest exists and research activities have grown over the last decade to investigate the development of renewable energies generated from natural sources, especially in the area of solar cells (or photovoltaics, PV), a high priority area of research in the European Research Area (ERA). Central to addressing this challenge is the development of novel materials with tunable optoelectronic properties. However, one class of materials that has received almost no attention at all is the aniline-based materials (polyaniline and its lower oligomers). The proposed research focuses on the design and synthesis of Self-Organising Liquid-Crystalline OligoAnilines for Photovoltaic Applications, making use of newly developed synthetic approaches to produce such tunable materials. Several series of oligomers with new architectures, liquid-crystalline properties and varied conjugation architectures and lengths will be produced. These will be characteristed and combined with suitable inorganic semiconductors. The nanoscale morphology of such photoactive blends will be optmised, and utilised to produce proof-of-concept photovoltaic devices. This research will open unexplored avenues through its interdisciplinary and multidisciplinary approach, i.e., it will rely on modern synthetic organic chemistry, chemicophysical analyses of optoelectronic properties, morphologies and structure relationships, self-assembly in the solid state, device fabrication and testing. It is expected that the research and training outcomes of this proposed research will impact across the mentioned range of disciplines, and contribute highly trained researchers and knowledge to a high priority area for both society and research within the EU as well as on an international level.";208592,8;208592,8;FP7-PEOPLE-2010-IEF;/MC-IEF;UNIVERSITY OF BRISTOL;UK;;;"/EMP;/EDU;/NET";1;0;0;1;0;0 102558;908108;SPIVOR;ONG;FP7-PEOPLE;PEOPLE-2007-4-2.IIF;FP7;Geometrical aspects of spin and vortex dynamics in electromagnetic and matter waves;2012-01-31;2013-01-30;;'The project is intended to reveal a unifying nature and fundamental geometrical features of the spin and vortex dynamics of classical electromagnetic and quantum-mechanical matter waves. The Berry phase, Magnus effect, and spin-Hall effect are attracting ever-increasing interest of scientists because of their potential applications in nano-physics, spintronics, quantum computing, etc. Simultaneously, the modern optics (including nano-optics, photonics, and plasmonics) offers unique possibilities to test and apply fundamental quantum-mechanical ideas within classical systems. The striking similarities of the spin and vortex dynamics in electromagnetic and matter waves call for an in-depth theoretical analysis which will be given within the framework of the present project. We will carry out extensive theoretical investigations of the propagation and scattering of electromagnetic waves in inhomogeneous and anisotropic media. A special attention will be paid to dynamics related to spin (polarization) and orbital (optical vortices) angular momenta of light. The research will be concentrated on various manifestations of spin-orbit-type interactions between intrinsic and extrinsic degrees of freedom of electromagnetic waves and quantum particles. We aim to develop a unifying theoretical approach to be able to describe specific features of behaviour of spins and vortices evolving in external fields. The approach will include the fundamental geometro-dynamical effects: the Berry phase, spin-Hall effect, and Magnus effect. Using scope of the host laboratory, we are going to perform experimental test of fine manifestations of these effects in classical optics, with potential applications to fiber optics, metamaterials, and remote sensing of turbulent atmosphere. We anticipate that realization of the project will contribute to the ability to control complex wave fields of different nature and, thus, will have a profound interdisciplinary impact and applications.';15000;15000;FP7-PEOPLE-2007-4-2-IIF;/MC-IIFR;A. Usikov Institute of Radiophysics and Electronics, National Academy of Sciences of Ukraine;UA;;;"/SCI;/COO";1;0;0;1;0;0 93335;234324;2020 INTERFACE;ONG;FP7-TRANSPORT;SST.2008.1.1.1.;FP7;Tailoring of Tribological Interfaces for Clean and Energy-Efficient Diesel and Gasoline Power Trains;2009-12-01;2013-05-31;;"Durability and friction control in internal combustion engines is currently delivered from a complex package of lubricant additives in a fully formulated engine oil. These oil additives, through tribochemical interaction with the surface, produce nanostructured composite, self-healing and smart tribofilms at the surface. 2020 Interface involves the design of the complete system; functionalised Diamond-like Carbon (DLC) coating and future generation lubricant to enable the Europe’s stretching targets in fuel economy and durability to be met. There has been much emphasis in research on designing new coatings technology such that the degree of complexity of surface systems has increased dramatically over the last decade. In boundary lubricated contacts, it is the interfacial nanostructured film, which results from tribochemical interactions between the surface and the lubricant additives, which dictates the system performance. No attempts have been made to incorporate “design” strategies into optimizing this interface and 2020 Interface tackles this through an interdisciplinary integrated experimental and theoretical approach. The benefits of this approach are accrued from substantial improved fuel economy (protection of natural resources), reduced emissions (protection of the environment) and improved durability (lower waste and maintenance). As the number of vehicles in the globe increases year on year without showing signs of reaching a plateau and the internal combustion engine remains the major platform for powertrain for the foreseeable future, the impact of this project will be large and long lasting. 2020 Interface brings together a world class consortium of 4 Universities, 1 research institute and 4 leading multinational companies from 8 EU countries together in complete supply chain to deliver fast track radical innovation in nanoscience through to a full set of novel lubrication technology platforms, for commercial applications in diesel and";3867414,15;2591690;FP7-SST-2008-RTD-1;/CP-FP;UNIVERSITY OF LEEDS;UK;"VOLVO TECHNOLOGY AB;SKF BV;FACULDADE CIENCIAS E TECNOLOGIA DA UNIVERSIDADE DE COIMBRA;INSTITUT JOZEF STEFAN;SULZER SOREVI;UNIVERSIDADE DE COIMBRA;SOLERAS ADVANCED COATINGS NV;LUBRIZOL LIMITED;RIJKSUNIVERSITEIT GRONINGEN;UNIVERZA V LJUBLJANI";"SE;NL;PT;SI;FR;BE;UK";/TRA;1;0;0;1;0;0 87727;215193;NANO-HOST;ONG;FP7-PEOPLE;PEOPLE-2007-1-1-ITN;FP7;Homogeneous Supported Catalyst Technologies: the sustainable approach to highly-selective, fine chemicals production;2008-10-01;2012-09-30;;This proposal is aimed at generating new fundamental knowledge and fostering new prospects and frontiers, training and transfer of knowledge in the field of highly efficient, highly selective, supported, recyclable catalysts. Target of the research programme are strongly innovative methodologies for the preparation, recovery and reuse of single-site, multipurpose, nanostructured catalytic materials, and the engineering of reactors based on these catalysts, as this represents an essential part towards the elaboration of sustainable production processes of high-added value fine chemicals. The approach pursued will be the immobilization of homogeneous catalysts, and particularly transition metal complexes, onto preformed (in)soluble supports (heterogenised catalysts). Materials defined at the nanometric level obtained by surface organometallic chemistry will be also included. The focus will be thereupon on their applications on specific, selected reactions. In this project, we plan to use advanced catalyst design to develop catalysts in which the support allows improvements in terms of activity, selectivity, catalyst lifetime and versatility, compared to their homogeneous counterparts. This will be an interdisciplinary, jointly executed research project encompassing complementary, synthetic (inorganic supports, ligands, organometallic compounds, functionalized polymers, dendrimers, nanoparticles), reactivity (homo- and heterogeneous catalyst screening and recycle, product analysis), characterization (advanced techniques for materials and in situ investigations), engineering (continuous-flow / supercritical flow reactors) and modelling activities.;3385388;3385388;FP7-PEOPLE-2007-1-1-ITN;/MC-ITN;CONSIGLIO NAZIONALE DELLE RICERCHE;IT;"THE UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS;AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS;BASF NEDERLAND BV;TECHNISCHE UNIVERSITEIT EINDHOVEN;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;KATHOLIEKE UNIVERSITEIT LEUVEN";"UK;ES;NL;FR;BE";"/EMP;/SOC;/EDU";1;0;0;1;0;0 96013;253554;TRANS;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IEF;FP7;Translation and Gender;2010-09-15;2012-09-14;;"Research in the area of gender and translation is relatively recent in the field of Translation Studies. Feminist theory in translation has brought us the understanding that translation is conflictual in that it engages many of the same kinds of active identity-forming processes as other language activities. Translation can thus provide us with valuable information about practices of domination and subversion in society. In light of contemporary explorations of cultural difference in Western society and theoretical works that question the basic duality of gender, research perspectives about translation and gender are multiple and very promising since much of the terrain is yet uncharted. Reserach in the area of cultural difference and its translation is crucial in a globalized world, as we have come to understand the commerce between languages to be central to the process of communication and to achieving lasting peace. Contemporary cultures are increasingly plural and Western society, as a whole, has turned into what has been called a vast "contact zone" in which intercultural relations contribute to the fabric of national cultures. The inscription of translation within contemporary writing, poetra and fiction is a clear indication that translation has now moved to the center of Western intellectual, social and cultural preoccupations. The place of women is also a major concern today in society. The aim of this project is to further advance research on translation and gender and to address some of the questions at the heart of contemporary debates. I will critically examine major contemporary perspectives on gender, culture and translation and analyze, from an interdisciplinary perspective, the works of the feminist historian Joan Scott and of the philosopher Judith Butler from the viewpoint of translation theory and practice. I will then explore Nancy Huston's practice of self-translation and crossover in the context of feminist theory and translation.";214530,4;214530,4;FP7-PEOPLE-2009-IEF;/MC-IEF;UNIVERSITE PARIS III SORBONNE NOUVELLE;FR;;;"/SCI;/EDU;/ITT";1;0;0;1;0;0 98337;272612;NANOLEDS;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-IEF;FP7;A Novel Approach to the Fabrication of Nanoscale Light Emitting Diodes;2011-06-01;2013-05-31;;"'Research in Nanoscience and Nanotechnology will drive the scientific and technological development of future years with revolutionary perspectives in many aspects of our society. Future large-volume applications will require fast and flexible methods to fabricate and miniaturize electronic and photonic components. This proposal will develop a novel approach to the fabrication of nanoscale light emitting diode (LED) and single quantum dot (QD) LED devices that exploits the laser-driven diffusion of hydrogen in III-V and III-N-V semiconductors. This project will impact a wide community. In fact, nano-LEDs have potential for several applications and interdisciplinary research, i.e. intra- and inter-chip communication, ultrahigh-density information storage, bio-imaging, etc.; also, single-QD LEDs will provide opportunities for fundamental studies of low dimensional structures and their exploitation in nanophotonics. Therefore, this programme of research is well suited to tackle important challenges faced by our society and to generate the knowledge needed to ensure the leadership of Europe in a rapidly growing field. This fellowship will offer Dr. G. Pettinari opportunities to acquire complementary competencies and skills and to reach a position of professional maturity and independence. The fellow will work in an internationally leading institution, The University of Nottingham, with a strong tradition in condensed matter and semiconductors research. The host institution will benefit from hosting a promising researcher whose innovative proposal and previous experience in hydrogen studies and III-N-V alloys will complement an existing research activity at Nottingham on the fabrication of nanoscale LEDs. Of particular interest is the proposal of using hydrogen in the miniaturization of photonic components. This approach has the potential to be implemented in different semiconductor systems and devices, thus opening realistic prospects for a wide range of applications.'";199549,6;199549,6;FP7-PEOPLE-2010-IEF;/MC-IEF;THE UNIVERSITY OF NOTTINGHAM;UK;;;"/EMP;/EDU;/NET";1;0;0;1;0;0 88904;215781;EVONET;ONG;FP7-PEOPLE;PEOPLE-2007-1-1-ITN;FP7;Evolution of gene regulatory networks in animal development;2008-10-01;2012-09-30;;Genetic and mutant analyses in Drosophila and other standard model organisms have revealed hierarchical gene networks and identified some key regulatory genes acting in animal development. While surprising conservation exists on a broad scale between distant phyla, significant differences have also been detected. Systems biology approaches in the main model systems have now revealed more complex gene regulatory networks (GRNs). To understand the logics and evolution of GRNs more basal animal phyla need to be studied. The comparative analysis of GRNs has thus become a new major focus of systems biology. The key questions are: (1) Does the higher complexity of some species correlate with an increase in complexity in GRNs? (2) How do GRNs evolve to drive changes in body plans? The major challenge for the next generation of researchers will be to integrate knowledge of developmental biology, bioinformatics, functional genomics and evolutionary biology. This requires a new combination of interdisciplinary training to bridge the gap between what are currently quite separate disciplines. In this ITN we will gather and compare information on GRNs from diverse animal systems, representing all major animal lineages, with particular emphases on the mesoderm specification network and the head regionalization network. To this end, we will provide early researchers with the skills necessary to apply state of the art systems biology, genomics and bioinformatics tools to emerging model organisms. The early researchers will receive an in-depth introduction into the selected model systems and training in how to conduct and analyze genomic experiments by the members of this ITN, which includes a company specialized in array technology. We will organize joint ITN/EMBO training courses and summer schools attended by three visiting renowned scientist, an exchange program between the ITN labs and a professional seminar in complementary skills.;2650000;2650000;FP7-PEOPLE-2007-1-1-ITN;/MC-ITN;UNIVERSITAT WIEN;AT;"UNI RESEARCH AS;THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;EUROPEAN MOLECULAR BIOLOGY LABORATORY;MAX-DELBRUCK-CENTRUM FUR MOLEKULAREMEDIZIN;STAZIONE ZOOLOGICA ANTON DOHRN;MEDICAL RESEARCH COUNCIL";"NO;UK;DE;IT";"/EMP;/SOC;/EDU";1;0;0;1;0;0 88826;222980;BETAIMAGE;ONG;FP7-HEALTH;HEALTH-2007-2.4.3-9;FP7;Use of innovative strategies for beta-cell imaging in diabetes mellitus;2008-10-01;2013-03-31;http://www.betaimage.eu/index.php;The development of sensitive, non-invasive methods for the characterisation and quantification of beta-cell mass would greatly enhance our means for gaining understanding of the pathophysiology of diabetes and allow the development of novel therapies to prevent, halt and reverse the disease. The aim of this project is to develop and apply innovative approaches for beta-cell imaging, the emphasis being on beta-cell mass regulation (loss and neogenesis) with the perspective of entering initial clinical trials. For this purpose, our approach is to: (1) Focus on imaging technologies offering the potential to enter clinical trials during the runtime of the project. Since beta cells contribute only marginally (1-2%) to the total mass of the pancreas, a highly sensitive method for clinical imaging is required. BETA IMAGE will focus on positron emission tomography (PET) relying on chemical resolution, i.e. the specificity of a radiolabelled tracer molecule. The lead compound will be radiolabelled Exendin 4, developed in the consortium for GLP-1 receptor imaging. (2) Devise novel imaging strategies by generating labelled “design” molecules/peptides/nanobody molecules targeting newly identified beta-cell surface proteins. These targets will be identified using a Systems Biology approach. For high-throughput tracer development, a stream-lined methodology will be established based on in vitro model systems and micro-/macroscopic in vivo real time dynamic imaging of tracer distribution by optical coherence tomography and complementary small animal PET and MRI. (3) Build on European excellence in tracer development using peptides, peptide-like and organic molecules for different imaging modalities. To achieve these ambitious goals, we have established a highly interdisciplinary and interactive project combining leading European research groups. In this way, a unique expertise is achieved regarding tracer development and imaging, beta-cells/diabetes and target definition.;7086487,59;5447136;FP7-HEALTH-2007-B;/CP-FP;STICHTING KATHOLIEKE UNIVERSITEIT;NL;"PHILIPPS UNIVERSITAET MARBURG;UNIVERSITE DE GENEVE;VRIJE UNIVERSITEIT BRUSSEL;ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE;UNIVERSITE LIBRE DE BRUXELLES;GABO:MI GESELLSCHAFT FUR ABLAUFORGANISATION:MILLIARIUM MBH & CO KG;PAUL SCHERRER INSTITUT;UNIVERSITAETSKLINIKUM FREIBURG;TURUN YLIOPISTO";"DE;CH;BE;FI";/MBI;1;0;0;1;0;0 88343;215080;DITANET;ONG;FP7-PEOPLE;PEOPLE-2007-1-1-ITN;FP7;novel DIagnostic Techniques for future particle Accelerators: A Marie Curie Initial Training NETwork;2008-06-01;2012-05-31;;The Council of the European Union expressively welcomed the development of a first European roadmap for research infrastructures. The aim of this recently published roadmap was to identify vital new infrastructures that are crucial for the future European research area, in particular for capacity building. These multi-disciplinary projects require substantial investments, forty percent of which are directly linked to new infrastructures using particle accelerators. This drastically underlines the importance of this field to ensure long-term European competitiveness in the sciences. The future Facility for Antiproton and Ion Research (FAIR), the X-ray Free Electron Laser (FEL) and the Large Hadron Collider (LHC) at CERN will provide a new set of beams to a truly interdisciplinary community. In addition, smaller scale projects are emerging that aim for novel studies with merged molecular beams or experiments with cooled antiprotons at lowest energies to pave the way for fundamental studies in a number of different fields. The development of new particle accelerators with unprecedented beam characteristics drives the need for an intense R&D program in diagnostic techniques. The successful operation of these machines will only be possible with adequate beam instrumentation. The aim of the here-proposed Marie Curie Initial Training Network is to develop beyond-state-of-the-art diagnostic techniques for future accelerator facilities and to train students and young researchers within a European network between several major research centres, leading Universities, and partners from industry.;4163329,38;4163329,38;FP7-PEOPLE-2007-1-1-ITN;/MC-ITN;THE UNIVERSITY OF LIVERPOOL;UK;"COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES;RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG;GSI HELMHOLTZZENTRUM FUER SCHWERIONENFORSCHUNG Gmbh;EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH;STIFTUNG DEUTSCHES ELEKTRONEN-SYNCHROTRON DESY;Heidelberg IonBeam Therapy Center GMBH;STOCKHOLMS UNIVERSITET;ROYAL HOLLOWAY AND BEDFORD NEW COLLEGE;UNIVERSIDAD DE SEVILLA;""INSTITUTUL NATIONAL DE CERCETARE -DEZVOLTARE PENTRU FIZICA SI INGINERIE NUCLEARA """"HORIA HULUBEI"""" (IFIN-HH)""";"FR;DE;CH;SE;UK;ES;RO";"/EMP;/SOC;/EDU";1;0;0;1;0;0 105997;302010;ISOZOO;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IIF;FP7;Isotopes of Zooplankton to measure climate and human impacts on pelagic food webs;2012-06-15;2014-06-14;;"'In all pelagic marine food-webs, zooplankton are the critical link between the phytoplankton primary producers and higher trophic levels, including fish. On-going changes observed for zooplankton communities in the Mediterranean and other oceans around the world therefore have serious implications for food-web productivity, and their continued provision of ecosystem services (e.g., food security). Current gaps in our knowledge of how the zooplankton component of the food-web functions, limit our ability to sustainably manage our marine resources. The ISOZOO program is designed to make a significant contribution to our understanding of zooplankton food-web processes, and how climate change and anthropogenic impacts affect these. Facilitated by IIF mobility, this overarching goal will be achieved by a multi and interdisciplinary approach, combining stable isotope ecology, ocean biochemistry, physical and biological oceanography, and ecosystem modelling. Working with a set of collaborators at the LOPB in Marseille, we will define Phyto-Zooplankton relationships across a range of nutrient conditions, and estimate the impact of these relationships on zooplankton food-chain length and transfer efficiencies. Established relationships between zooplankton and phytoplankton-nutrients will be used to: 1. develop an Index of zooplankton food-web status that can be applied to monitor food-web response to changing ocean conditions (physics & nutrients) and, 2. parameterise the Eco3M bio-physical model for the Gulf of Lion, to simulate/predict the impacts of climate change and anthropogenic forcing on ecosystem function. Together objectives 1 and 2 should allow for better informed management of marine resources given future variability. Through collaboration beyond the time frame of this project we aim to develop world-wide application of the Food-Web Index (1) and model parameters (2) through networks of international collaborators for climate change monitoring and research.'";269096,4;269096,4;FP7-PEOPLE-2011-IIF;/MC-IIF;UNIVERSITE D'AIX MARSEILLE;FR;;;/SCI;1;0;0;1;0;0 90193;229712;CEMP;ONG;FP7-PEOPLE;PEOPLE-2007-2-3.COFUND;FP7;The NBIPI Career Enhancement Mobility Programme;2009-03-02;2012-06-01;;The aim of the NBIPI Career Enhancement and Mobility Programme (CEMP) is to support experienced fellows at various stages of their career in attaining and strengthening their career prospects to become independent investigators or senior scientists in education or industry. Within the remit of the National Biophotonics Imaging Platform Ireland (NBIPI), the CEMP will fund and support research fellows wishing to undertake interdisciplinary research and training programmes in biophotonics and imaging. The CEMP will offer a combination of incoming and outgoing fellowships. The fellowship duration will range from 6-24 months and outgoing fellowships will include a mandatory reintegration phase. A 24 month incoming fellowship can include a re-integration phase of max 12 months in the Institution of origin. Training activities will include not only training-through-research under supervision by means of an individual personalized project but also in the following skill areas: • Hands-on training activities for developing scientific and complementary skills (to include proposal preparation for grant funding, patent applications, project management, tasks coordination, technical staff supervision) • Management of the transfer of knowledge and intellectual property • Capacity to build collaborations • Scientific and financial management of the research project The programme will also address the training requirement in team leadership and management. The NBIPI context of the proposed fellowship programme will offer research fellows the opportunity to carry out the research project of their choice in state of the art research facilities and to enhance their scientific and technical skills through a broad selection of training modules.;2422260;968904;FP7-PEOPLE-2007-2-3-COFUND;/MC-COFUND;ROYAL COLLEGE OF SURGEONS IN IRELAND;IE;;;"/REG;/SCI";1;0;0;1;0;0 93930;249206;SA-WSN;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-RG;FP7;Spectrum-Aware and Reliable Wireless Sensor Networks for Europe’s Future Electricity Networks and Power Systems;2009-11-02;2013-11-01;;"In this proposal, a Spectrum-Aware and Cross-layer Communication framework is proposed to realize efficient wireless sensor networking for currently envisioned smart grid applications. The proposed framework is a complete cross-layering such that the functionalities of traditional communication layers are melted in a customized cross-layer communication module for resource-limited sensor nodes to decrease the overhead and improve performance of traditional layered approaches. It also uses spectrum-aware spectrum access techniques to achieve a more efficient spectrum utilization by adapting to the availability of communication resources in harsh power system environments, which varies greatly with location, time and frequency because of obstructions, node contentions, RF interference and extreme noise. The specific goals of this project are: 1) Development of accurate analytical models to capture the characteristics of the wireless channel in power system environments; 2) Design of cross-layer & cognitive communication solutions enabling efficient utilization of the wireless channel, thus providing researchers with building blocks to ensure QoS for the envisioned applications; 3) Experimental verification of models and protocols with field tests; 4) To bridge the performance gap between sensor networking theory and real-world smart grid deployments by using an interdisciplinary research approach and international collaborations. Overall, this project will enable the PI to advance the field of wireless sensor networking and smart electric power grid applications as well as educating and inspiring the next generation of engineers in Europe. To this end, it addresses research, educational,and community service goals of IRG FP7 Work Program. Also, this research grant will help the PI to contribute to the European utility industry’s competitiveness, success of the European host university, and to become an integral part of the European research community.";100000;100000;FP7-PEOPLE-2009-RG;/MC-IRG;BAHCESEHIR UNIVERSITESI FOUNDATION;TR;;;/SCI;1;0;0;1;0;0 100179;282574;UNCOVER;ONG;FP7-HEALTH;HEALTH.2011.4.1-2;FP7;Evaluation and development of measures to uncover and overcome bias due to non-publication of clinical trials;2011-09-01;2014-06-30;;"The UNCOVER project is a direct contribution to overcome non-publication of clinical studies that have been designed and executed as randomized controlled trials (RCTs). RCTs provide the best utility as input to systematic medicinal reviews, one cornerstone of evidence-based medicine. That is provided that, and only then, RCTs are both correctly registered and published at least once. Because non-publication, as well as publication with time delay of RTCs, can decisively reduce the advantage of such systematic reviews of drugs, medical devices or procedures, it affects the knowledge base, patient value, and level of public health. UNCOVER’s aim is three-fold: 1) to apply established and develop novel, solid, and useful methods for fact-finding and interventions into the socio-economic system defined by causes and sources of the publication bias; 2) to engage with stakeholders and identify strategies, barriers, and facilitating factors associated with the publication bias and its consequences; and 3) to synthesize lessons learned and recommend feasible measures to deal with the publication bias. In a perspective way, this project contributes pro better allocation of funds to sponsor studies and patient value, and contra duplication of work and patients risk. The issues of the publication bias are treated with quantitative, qualitative and participatory means (including tools such as stakeholder maps, institutional analysis, case studies, systematic reviews, interviews, bibliometric analysis and software) in an interdisciplinary approach in areas with little or no lines of evidence as to how they perform in practice. UNCOVER will thus both provide viable solutions for the publication bias, for better allocation efficiency of medicinal and health related research funds, and develop methodologies for future bias research efforts.";683804;498801,84;FP7-HEALTH-2011-single-stage;/CSA-SA;AIT AUSTRIAN INSTITUTE OF TECHNOLOGY GMBH;AT;"UNIVERSITAT FUR WEITERBILDUNG KREMS;THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL";"AT;US";/LIF;1;0;0;1;0;0 92442;227030;CONVERGE;ONG;FP7-ENVIRONMENT;ENV.2008.4.2.3.1.;FP7;Rethinking Globalisation in the light of Contraction and CONVERGEnce;2009-09-01;2013-08-31;;"'The CONVERGE project will build from the concept of 'contraction and convergence' that informed the Kyoto process. C&C linked the key social concept of equal rights to emissions with the key ecological need for reduced emissions to issue a challenge to economic systems to develop fair processes for emissions reduction. CONVERGE aims to re-think globalisation by developing our understanding of convergence beyond emissions-trading across wider social, economic and ecological dimensions of sustainability. CONVERGE will research, develop and test the processes of contraction, convergence and divergence in current forms of globalisation. The research will be based on systems science to integrate social, scientific and economic disciplines in order to create coherent solutions to complex problems. Key to the success of this study is the interdisciplinary approach and working with stakeholders from civil society, government and business. CONVERGE seeks to explore convergent sustainability relationships across different scales from local, national, global-regional to global. CONVERGE will research current examples of convergence in communities, policies and indicators moving towards sustainability. The project will develop a convergence frame for understanding and development in civil society and policy communities; accessible publications providing guidance and tools for the use of this framework; a set of Convergence indicators, quantitative and qualitative, that will be used to test and model the processes of convergence including development of a Computer Programme; and recommendations to assist policy makers to integrate C&C into the decision making process. CONVERGE will play a significant role in achieving the strategic objective of EUs global partnership: 'to promote sustainable development actively worldwide and ensure that the European Union's internal and external policies are consistent with global sustainable development and its international commitments.'";1745968,18;1398152;FP7-ENV-2008-1;/CP-FP;DR. E.F. SCHUMACHER SOCIETY LIMITED;UK;"GREENDEPENDENT INTEZET NONPROFIT KOZHASZNU KORLATOLT FELELOSSEGU TARSASAG;SOCIAL CHANGE AND DEVELOPMENT;GREENDEPENDENT - SUSTAINABLE SOLUTIONS ASSOCIATION;The Natural Step International;SZENT ISTVAN UNIVERSITY;THE SCHUMACHER CENTRE LTD;UNIVERSITY OF BRISTOL;LUNDS UNIVERSITET;HASKOLI ISLANDS";"HU;IN;SE;UK;IS";/SDT;1;0;0;1;0;0 93109;244909;WORKABLE;ONG;FP7-SSH;SSH-2009-1.1.1.;FP7;Making Capabilities Work;2009-11-01;2012-10-31;http://www.workable-eu.org/;"“Making Capabilities Work” (WorkAble) will scrutinise strategies to enhance the social sustainability and economic competitiveness of Europe by strengthening the capabilities of young people to actively shape their personal and work lives in knowledge societies and cope with today&amp;apos;s economic, cultural, demographic and technological challenges. Bridging quantitative and qualitative methods, WorkAble will assess the potential of innovative European strategies for dealing with local labour-market demands and regional inequalities. Adopting a comparative and interdisciplinary approach, it will systematically analyse whether and how young people are enabled to participate in working life and society. Applying the Capabilities Approach as a common heuristic framework, 12 partners from different disciplines (educational science, sociology, economics, philosophy, political studies and social work) in 10 European countries will collaborate closely in a multidimensional research process. WorkAble will survey whether and how the match between young people’s supply of skills and competencies and changing labour-market needs is sustained and secured, while simultaneously broadening their options for living in and actively shaping European knowledge societies. It will explore how educational strategies are implemented and assess whether they enable young people to convert knowledge, skills and competencies into capabilities to function as fully participating active citizens. This calls for a three-phase research design: 1) a comparative institutional mapping and analysis of vocational and labour-market policies in all educational regimes; 2) case studies to reconstruct the conceptions, aspirations and practices of local actors implementing educational and training programmes; and 3) quantitative secondary analyses of national and European longitudinal data revealing how effectively these strategies enhance economic performance and close the capability gap for young people.";2860441,6;2264789;FP7-SSH-2009-A;/CP-FP;UNIVERSITAET BIELEFELD;DE;"AARHUS UNIVERSITET;UNIWERSYTET WARSZAWSKI;UNIWERSYTET IM. ADAMA MICKIEWICZA W POZNANIU;BBJ CONSULT AG;UMEA UNIVERSITET;CENTRE D'ETUDES ET DE RECHERCHES SUR LES QUALIFICATIONS;UNIVERSITA DEGLI STUDI DI PAVIA;EDINBURGH NAPIER UNIVERSITY;UNIVERSITA' DEGLI STUDI DI MILANO-BICOCCA;Forschungs- und Beratungsstelle Arbeitswelt;HAUTE ECOLE SPECIALISEE DE SUISSE OCCIDENTALE;GOETEBORGS UNIVERSITET";"DK;PL;DE;SE;FR;IT;UK;AT;CH";"/SOC;/EDU";1;0;0;1;0;0 93617;241958;AXLR8;ONG;FP7-HEALTH;HEALTH-2009-1.3-1;FP7;Accelerating the transition to a toxicity pathway-based paradigm for chemical safety assessment through internationally coordinated research and technology development;2010-01-01;2013-10-31;;"Conventional approaches to toxicity testing and risk assessment are often decades old, costly and low-throughput, and of dubious relevance to humans. These factors have prompted leading scientific bodies to call for a transition to a 21st century paradigm, including a move away from apical outcomes at high doses in whole animals, and toward a mechanistic understanding of the source-to-outcome continuum between xenobiotic exposure and adverse health effects. Such a shift will require a robust understanding of the cellular response/toxicity pathways which that can lead to adverse effects when perturbed; appropriate in vitro systems to study chemical interactions at key targets along a pathway; and computational systems biology models to describe the “circuitry” underlying each pathway as a basis for creating biologically realistic dose-response models. The AXLR8 project aims to support the transition to a toxicity pathway-based paradigm for quantitative risk assessment, and to this end will: 1) Organise a series of scientific workshops and expert meetings to map and catalogue research progress, gaps and needs in the above areas. 2) Provide a range of tools and opportunities for enhanced interdisciplinary and international communication, coordination and collaboration in order to maximise the impact of available resources. 3) Work to streamline regulatory acceptance procedures to provide for the expeditious uptake of validated 3Rs methods, including a smooth transition to 21st century systems as they become available. 4) Produce an authoritative report on the state of the science, including a practical roadmap detailing priority research and funding targets, in order to ensure a prominent role for European science in this rapidly developing global research area.";612800;555223;FP7-HEALTH-2009-single-stage;/CSA-CA;FREIE UNIVERSITAET BERLIN;DE;"VLAAMSE INSTELLING VOOR TECHNOLOGISCH ONDERZOEK N.V.;THE HUMANE SOCIETY INTERNATIONAL (UK)";"BE;UK";"/MED;/MBI";1;0;0;1;0;0 98959;275855;CAPACITI;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-IEF;FP7;"""Carbon dynamics in Pyrenean grasslands: a first-time assessment with ecosystem fluxes, isotopic marking, and plant guilds""";2011-07-01;2013-06-30;;"'Given the vulnerability of mountain ecosystems and their importance as carbon storage systems, there is a pressing need to understand how mountain grassland ecosystems function –with the aim to asses the impact of global change and to determine the management mechanisms that can ameliorate its effects. This proposal focuses on the study of the annual C dynamics of semi-natural grazed grasslands in the Pyrenees. The central question will be to resolve how management and climate combine to regulate their productivity and carbon storage capacity. This will be pursued with multi-site analysis of ecosystem dynamics from eddy correlation towers data (description of annual cycles and main biotic and abiotic controlling factors, annual carbon balance, partition of ecosystem fluxes), process understanding (compartment functioning through stable isotope analyses and gas-exchange chambers), and exploration of process-based relationships to evaluate C balance in mountain pastures. Emphasis on the potential role of plant guild distribution as ecosystem regulators will be transversal to all activities. Dr Altimir will be hosted for a 24-month visit at the Technological Forestry Centre of Catalonia (Spain), where she will join the research at the Laboratory of Functional Ecology and Global Change. This group offers experience in grassland ecology as well as cooperation with isotope researchers. The groups coordinates the transnational and interdisciplinary project FLUXPYR and its unprecedented multi-site network for the integrated study of the carbon, energy and water cycles in the Pyrenean agro-ecosystems. Dr Altimir will receive training for an advance career level, emphasizing on project management and supervision skills. She will be also specifically trained for the use isotopic techniques, and guided in the characterization of plant guilds. Secondarily, she will be instructed in the application of remote sensing techniques as validation tools for ecosystem models'";232480;232480;FP7-PEOPLE-2010-IEF;/MC-IEF;CONSORCI CENTRE DE CIENCIA I TECNOLOGIA FORESTAL DE CATALUNYA;ES;;;"/EMP;/EDU;/NET";1;0;0;1;0;0 94244;228869;MATRANS;ONG;FP7-NMP;NMP-2008-2.5-1;FP7;Micro and Nanocrystalline Functionally Graded Materials for Transport Applications;2010-02-01;2013-01-31;http://www.matrans.kmm-vin.eu;MATRANS aims at development of novel metal-ceramic functionally graded materials (FGMs) for aerospace and automotive applications in: (i) exhaust and propulsion systems, (ii) power transmission systems, and (iii) braking systems, with the main objective to enhance the mechanical properties of these materials through spatial variations of material composition and microstructure. Specifically, MATRANS deals with two groups of bulk FGMs: (i) ceramics-copper/copper alloys, (ii) ceramics-intermetallics. These FGM systems have not yet been used in the transport sectors targeted. The MATRANS methodology is problem oriented and comprehensive combining interrelated activities of material processing (core activity of the project), characterisation, modelling and demonstration. The processing will encompass starting materials (e.g. nanopowders) and the resulting FGMs. Characterisation of the FGMs will include detailed description of microstructure, measurements of physical and mechanical properties and residual stresses. The modelling will be carried out at a design phase and for the material response to combined thermomechanical loading and extreme service conditions. Extensive use of multiscale approaches and numerical methods will be made. The project addresses the joint design of the FGM and the structural component it is intended for. Economical and ecological aspects of processing are included. Risks aspects of material non-performance will be tackled, too. MATRANS has mobilized a critical mass of interdisciplinary expertise and highly specialized equipment. The consortium includes leading groups from materials science, physics, chemistry, mechanical engineering and computer science. The industry and SME involvement in the project is substantial. As the exploitation measures, the industrial partners will define business plans and start pilot cases during the project, followed by upscaling activities after the project end.;4918660;3600000;FP7-NMP-2008-SMALL-2;/CP-FP;European Virtual Institute on Knowledge-based Multifunctional Materials AISBL;BE;"USTAV MATERIALOV A MECHANIKY STROJOV SLOVENSKEJ AKADEMIE;CENTRO RICERCHE FIAT SCPA;NATIONAL TECHNICAL UNIVERSITY OF ATHENS - NTUA;FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.;AIRBUS DEFENCE AND SPACE GMBH;TECHNISCHE UNIVERSITAET KAISERSLAUTERN;Steinbeis Advanced Risk Technologies GmbH;POLITECHNIKA WROCLAWSKA;CARDIFF UNIVERSITY";"SK;IT;EL;DE;PL;UK";/NNT;1;0;0;1;0;0 97235;262632;SOLVER;ONG;FP7-SME;SME-1;FP7;Solvent purification and recycling in the process industry using innovative membrane technology;2010-12-02;2012-12-01;;Solvents are widely used in process industries such as chemical, petrochemical, pharmaceutical, food, biotechnology and microelectronics. The recovery of spent solvents containing all types of impurities presents a vast market, targeting thousands of small to medium sized companies in Europe that are generating highly as well as marginally polluted solvent streams. Many current solvent purification and manufacturing practices utilise a traditional, energy-intensive distillation-based technology in the production and/or recovery of liquid chemicals. This method of processing is costly, inefficient and produces a significant volume of hazardous waste. This project, SOLVER, proposes to debottleneck the heating step as well as the thermal chemical reactions involved, and replace them with membrane separation techniques working at room temperatures and able to achieve separations at the molecular level, i.e. pervaporation (PV) and organic solvent nanofiltration (OSN). Such chemical process intensification in solvent recovery and purification is expected to lead to significant improvements in product cost, materials usage, energy and waste reduction, as well as a decrease in risk and hazards. Thanks to the interdisciplinary and complementary skills of the consortium members, SOLVER aims at demonstrating the potential of OSN/PV technology in solvent manufacturing through lab-scale and pilot testing, but also at more fundamentally understanding the processes and the behavior of the membranes during filtration. The latter will be pursued by advanced characterization and on-line process monitoring tools. SOLVER joins two types of innovative SME end-users building out new business lines to stay ahead of competition. Two SMEs are active in solvent recycling/manufacturing, the other two in OSN/PV membrane production. The SME partners form a strategic supply chain and are expected to continue to leverage on the technological head-start after the project, take the results of the RTD work directly to the market, find new applications for their products, and be the market leaders in their respective sectors.;959038,62;658734,62;FP7-SME-2010-1;/BSG-SME;VLAAMSE INSTELLING VOOR TECHNOLOGISCH ONDERZOEK N.V.;BE;"PERVATECH BV;SOLSEP BV;GKA Technologies Limited;FUNDACAO DA FACULDADE DE CIENCIAS E TECNOLOGIA DA UNIVERSIDADE NOVA DE LISBOA.;DE NEEF CHEMICAL PROCESSING NV;PACKO INOX NV";"NL;IE;PT;BE";"/ECO;/SCI";1;0;0;1;0;0 92378;239546;MCM;ONG;FP7-PEOPLE;PEOPLE-2007-4-3.IRG;FP7;Neural Mechanisms Underlying Mate Preference and selection in Mice;2009-10-01;2013-09-30;;"Mate choice is a behavior observed through all animal kingdom with deep evolutionary consequences, since only the genes of animals that can successfully mate will pass to the next generation. If not everybody has the ability of passing its genes, this means that each individual looks different at the eyes of choosers, which has classically been approached in terms of attractiveness. Mate selection implies 3 steps: 1) prospective mates have different attractiveness; 2) prospective mates broadcast signals that correlate with their attractiveness; 3) choosers can sense those signals and make a decision accordingly to their preferences. To influence animal´s decision, attractiveness cues must be picked up by the sensory systems of choosers and translated into electrical signals that can be used by higher brain structures to make a decision. A lot of effort has been dedicated to elucidate the nature of the cues utilized to broadcast attractiveness, but very little is known about the mechanistic basis for mate preference, how the decision to select a better mate based on the animal´s preferences is taken and how it is used to trigger the appropriate copulatory behavior. My long term goal is to obtain a mechanistic understanding of how the brain implements the necessary computations to achieve this goal. Using mice, my aims during the next 4 years are: 1) establish a behavioral paradigm to study mate preference and selection; 2) identify brain circuits involved in this behavior using immediate early genes as markers of neuronal activity; 3) using genetic tools, manipulate the activity of specific circuits to bias behavior. These studies will use an interdisciplinary approach to bridge evolutionary biology and neurobiology, and hopefully getter at a deeper understanding of this decision making process.";100000;100000;FP7-PEOPLE-IRG-2008;/MC-IRG;FUNDACAO CALOUSTE GULBENKIAN;PT;;;"/SCI;/COO";1;0;0;1;0;0 93197;249018;SHAPE;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-RG;FP7;Control of cell morphogenesis: Bacterial cell wall and actin-cytoskeleton;2009-10-01;2013-09-30;;A fundamental question in cell biology is how cells determine their shape. Each life form is surrounded by boundary layers that protect, communicate with the environment, and may confer shape and rigidity. However, little is known about the mechanisms determining cell shape, and the broader questions concerning morphogenesis are the same in prokaryotic and eukaryotic systems. How is cell shape regulated temporally and spatially? How is structural information acquired and maintained? In bacteria, the tough external peptidoglycan cell wall is known to be a primary determinant of cell shape. But despite decades of studies, both its ultra-structure and the molecular mechanisms that control wall morphogenesis are poorly understood. A radical change recently occurs with the discovery of a bacterial actin-like cytoskeleton as a primary determinant of cell wall biogenesis. Moreover, actin homologues (MreB family) are not only involved in cell morphogenesis but also in DNA segregation and cell polarity, suggesting a key function in cell development. However, the mechanistic details and the effectors used by MreB proteins to fulfil these roles remain to be elucidated. The general aims of this project are to elucidate the factors controlling bacterial cell wall morphogenesis and to determine the different functions of the bacterial cytoskeleton and the mechanisms underlying them. For this, an interdisciplinary approach combining the methods of genetic, microscopy, biochemistry, physico-chemistry and mathematical modelling will be used.;100000;100000;FP7-PEOPLE-2009-RG;/MC-IRG;INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE;FR;;;/SCI;1;0;0;1;0;0 93385;249235;EHCO & QOL;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-RG;FP7;EMERGENT HEALTH-CARE OCCUPATIONS & QUALITY OF LIFE: A STUDY OF THE USA, SPAIN & ITALY;2009-10-01;2013-09-30;;"This project aims to understand the dynamic structuring of emergent occupational and organizational forms in health care services. Employment growth in health related fields leads labor markets today. This growth results from a well known economic and demographic phenomenon affecting mostly Europe and North America, namely, the increasing demand for healthcare and social assistance because of an aging population and longer life expectancy. These social changes imply more than just a growing need for management of the expanding provision of health care and social services. They also mean profound transformations in the institutional and social settings where care is given, as the health care system moves away from large hospitals and centers around focused-care organizations and individuals’ homes. However, limited research exists concerning the effect of these changes on the emergence of new occupations and the need for multidisciplinary work approaches in caring for the aged. In addition, there is little in understanding the educational programs necessary to develop competencies in these jobs. Because these trends encompass large geographical regions (Europe and USA) and involve different disciplines such as health management, labor relations and sociology of work, the Researcher has built an international and interdisciplinary team of scholars from the USA, Italy and now Spain. Overall, the project aims to achieve: (a) an understanding of health caregivers’ jobs and the design of a corresponding educational program, that would permit employees to effectively deliver quality care; (b) an adequate definition of healthy elderly quality of life (QOL), departing from the multiple conceptualizations currently used in research; and (c) a theoretical framework that would help categorize the growing number and type of organizations and occupations in the health care sector.";100000;100000;FP7-PEOPLE-2009-RG;/MC-IRG;UNIVERSIDAD DE NAVARRA;ES;;;/SCI;1;0;0;1;0;0 99572;274914;POLMIN-1418;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-IEF;FP7;"""National Minorities at War: Integration, Identity and Combat Motivation among Poles in German and Austro-Hungarian Society, 1914-18""";2011-10-01;2013-09-30;;'The rise of globalisation since the Second World War has entailed not only large movements of goods and capital across European borders but also mass migration. By 2005, 8.6 per cent of the inhabitants in EU-25 countries were foreign-born. The issue of how best to integrate socially these often ethnically and religiously diverse peoples has become an important subject of debate both within individual nations and at the level of the Commission of the European Communities. Often forgotten, however, is the fact that this dilemma is not new. This project will provide original insights into minority integration through a comparative historical case study. It takes as its focus the Polish minorities living within German and Austro-Hungarian borders during the First World War. In the forty years before 1914, these two states had adopted diametrically opposed policies to win Poles’ loyalties: whereas German governments had pursued obtrusive campaigns of cultural and linguistic assimilation, Austria-Hungary had granted extensive political and cultural autonomy. By comparing Poles’ readiness to defend these states in 1914, as well as their subsequent commitment to their rulers’ war efforts, the study will assess which method of integration proved more successful. Two further outcomes, contributing to two interdisciplinary academic debates, are also expected from this research. Firstly, by examining Poles’ attitudes and conduct during the years 1914-18, the project will shed light on the growth of Polish national identity in the early twentieth century and engage with sociological and political scientific literature on the relationship between war and the rise of national consciousnesses. Secondly, by evaluating the performance of Polish troops fighting for Fatherlands which were not their own, the study will help to resolve the longstanding scholarly controversy about the importance of ideological beliefs, especially patriotism, for martial efficiency.';207790;207790;FP7-PEOPLE-2010-IEF;/MC-IEF;UNIWERSYTET WARSZAWSKI;PL;;;"/EMP;/EDU;/NET";1;0;0;1;0;0 89571;203376;ATTACHMENT AND OCD;ONG;FP7-PEOPLE;PEOPLE-2007-4-3.IRG;FP7;Attachment anxiety, Self Structures and Obsessive Compulsive Disorder (OCD);2007-10-01;2011-09-30;;We aim to investigate, via experimental tasks, the nature of the relationships between attachment anxiety, self structures and key phenomenological features of obsessive compulsive disorder (OCD) in order to inform conceptualisations and improve psychological treatment of this disorder. In Study 1, we aim to assess whether the triggering of attachment-anxiety is associated with lower implicit self esteem (ISE) and greater urge to act in response to scenarios previously shown to be OCD-relevant. It is hypothesized that triggering attachment-anxiety will decrease ISE and result in greater urge to act in response to OCD-related scenarios. Conversely, in Study 2, we aim to assess whether priming attachment security is associated with higher implicit self esteem (ISE) and lesser urge to act in response to scenarios previously shown to be OCD-relevant. It is hypothesized that enhancing attachment security will increase ISE and result in lesser urge to act in response to OCD-related scenarios. In Study 3, we will investigate whether suppressing intrusive thoughts rated as personally meaningful will lead to decreased ISE, particularly for individuals with high attachment-anxiety. We expect the suppression of intrusive thoughts considered indicative of hidden self-aspects will result in lower ISE, in particular for individuals with high attachment-anxiety. In Studies 4, 5 and 6, we aim to replicate the findings in a clinical OCD sample. The proposed research involving the integration of OCD, cognitive, attachment and self research is consistent with the aim of creating internationally competitive ‘state of the art’, interdisciplinary research capacity within the EU. Given the expertise of the host organization, collaborator (from the applicants’ previous residence) and applicant in the development and dissemination of evidence-based psychological research, the successful reintegration of the applicant into the EU research community is extremely high.;100000;100000;FP7-PEOPLE-2007-4-3-IRG;/MC-IRG;INTERDISCIPLINARY CENTER (IDC) HERZLIYA;IL;;;"/SCI;/COO";1;0;0;1;0;0 92492;231023;TIEM;ONG;FP7-PEOPLE;PEOPLE-2007-4-3.IRG;FP7;"TRACING IDENTITY IN THE EASTERN MEDITERRANEAN; A Digital Survey of Late Medieval Monuments in the Eastern Mediterranean Islands";2009-06-01;2013-05-31;;"This project proposes the interdisciplinary examination of the monumental heritage of the Medieval Mediterranean. Specifically, the program’s objective is the creation of a comprehensive digital repository of the late medieval monuments of the islands of the Eastern Mediterranean using state-of-the-art technological tools. Research will cover the eastern part of the Mediterranean basin beginning with Cyprus, Rhodes and Chios to be progressively extended to Crete and other Aegean islands. The program offers a novel methodology that adjusts to the complex socio-political realities of the Medieval Mediterranean. Research focuses on the understudied period that followed the collapse of the Latin kingdom of Jerusalem in 1187 until the capture of Crete by the Ottomans in 1669. In this volatile environment, Cyprus, Chios, Rhodes and Crete became Europe’s gateways to the East; as such, they will be the central examples of this study. These islands will not be isolated studies but the pivotal mirrors to explore the region. The proposed methodology offers three levels of analysis starting from the broader geographical bodies and their location in the region, then moving to the specific locales, to finally study individual monuments. The application of informatics, GIS technologies, the use of digital libraries, and the utilization of scanning and CAD technologies will offer an invaluable record of extant architectural and archaeological remains. The in-depth documentation of surviving monuments in the above islands will be followed by the comparative examination of physical evidence against textural sources and the historical background of the period. Hosted by the Cyprus Institute, the proposed program traces aspects of the formation and appropriation of social and religious identity in the Medieval Mediterranean. This is a topic of great contemporary relevance for the EU as it offers an enhanced understanding of the intricate cultural realities of the broader region.";100000;100000;FP7-PEOPLE-IRG-2008;/MC-IRG;THE CYPRUS RESEARCH AND EDUCATIONAL FOUNDATION;CY;;;"/SCI;/COO";1;0;0;1;0;0 98722;277115;NEOLIBERAL_CITI;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-RG;FP7;NEOLIBERAL_CITI: Re-framing urban neoliberalism and neo-liberal citizenship – Enactments of resistance and practices of protest;2011-04-01;2014-03-31;;"'The widespread proliferation of neoliberal ideology and the application of its central principles to urban development can be portrayed as key aspects that introduced major modifications in the ways urban politics are conceived today. Such transformations do not exclusively apply to the political sphere – neoliberalism has also affected the habits of how people imagine, perceive and appropriate urban spaces in their daily life. Cities play a strategic role in the variegated geographies of neoliberalism, but relatively little research critically assessed conceptually the challenges democracy faces in neoliberal societies. The interdisciplinary research project NEOLIBERAL_CITI will tackle this gap – it investigates the discourses and practices of contest and re-appropriation of urban space, thus providing a novel understanding of how opposition against neoliberal urban development and neo-liberal citizenship is being re-framed after the recent financial and economic crisis. Against the background of the application of innovative qualitative methodologies such as reflexive photography and biography-oriented narrative interviews, the project aims at advancing theoretical debates within citizenship studies and urban geography as well as at producing new empirical insights to the broader implications of urban neoliberalism. The design of the research project responds to the sound embedding the applicant has within areas such as critical urban research, social theory, citizenship studies and human geography. Additionally, he is a recognised expert for the implementation of qualitative empirical research. The development of NEOLIBERAL_CITI gives him the opportunity to constitute an independent research group about neoliberal urbanism and neo-liberal citizenship at his host institution. Such an aim responds both to the position of professional maturity and the long-lasting professional stability he was recently offered.'";45000;45000;FP7-PEOPLE-2010-RG;/MC-ERG;UNIVERSIDAD AUTONOMA DE MADRID;ES;;;/SCI;1;0;0;1;0;0 95766;250594;MENTALCAUSE;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IEF;FP7;The Ontology of Mental Causation;2010-09-01;2011-08-31;;"The proposal being submitted is an interdisciplinary project belonging to the area of ontology of mind. The long-term goal of the project is to find an answer to the question whether a consistent conception of events, properties and agents can be proposed and defended which would make it possible to speak about irreducible, causally potent, mental factors. Subsequent research stages of the project are: (1) The analysis of anti-dualistic arguments: the supervenience argument, the exclusion argument, the overdetermination argument; (2) The comparative and reductive analysis of causal relata; (3) The analysis of causal relation; (4) The analysis of dispositional properties; (5) The ontology of subjects of experience as rational selves and free agents. As a result of the research project, I expect: (i) preparing and developing an adequate terminology in which issues in mental causation can be framed; (ii) analysing the problem of causal relata and causal relation itself and formulating basic theses in otology of properties, events and agents; (iii) reconstructing and critically analysing anti-dualistic arguments; (iv) recognizing interconnections between various groups of metaphysical and scientific problems intertwined with such notions as overdetermination, causal closure of the physical domain, realization, determination, ontological dependence and emergence; (v) critically analysing some of the options within the mental causation debate such as anomalous monism, reductive and non-reductive physicalism and emergent dualism; (vi) developing a sufficiently rich ontology of the human person which will be in position to deliver persuasive answers to the most frequent questions that appear within the mental causation debate and the metaphysics of human being.";117544,8;117544,8;FP7-PEOPLE-2009-IEF;/MC-IEF;UNIVERSITY OF DURHAM;UK;;;"/SCI;/EDU;/ITT";1;0;0;1;0;0 95965;251816;GPSMB-PPSPLITTER;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IOF;FP7;A New Hybrid Solution for the Propane/Propylene Separation: the Gas-Phase Simulated Moving Bed PP Splitter;2010-09-08;2012-01-07;;"Propylene is one of the world’s more important commodities, and the propane/propylene separation, usually performed by means of cryogenic distillation, one of the most difficult as energy-consuming operations currently practiced. Consequently, extensive studies have been developed to provide more sustainable solutions (mainly Pressure Swing Adsorption (PSA) and membrane technology), but presenting low recovery values as high-energy gaps in de/compression necessities. Recently, the Laboratory of Separation and Reaction Engineering (LSRE-FEUP) researchers’ applied an continuous counter current chromatographic apparatus (Simulated Moving Bed, SMB) to this separation proving its feasibility with high purity propylene (>99.5%), high recovery (>99.0%) and quite promising productivity values >1000 kg of propylene/(m3zeolite.h) with less than half of distillation cooling as heating necessities. However, it is still necessary to prove its competitiveness. One will only have this point cleared if we simulate the complete process (SMB plus desorbent recovery units), optimize and consider different adsorbents, desorbents as the inclusion of different technologies: hybrid solutions. To accomplish it, an interdisciplinary approach must be employed: from the physical fundamentals (adsorption, distillation, membranes), thru optimization to the economic analysis. LSRE-FEUP will contribute with adsorption and membranes expertise, while one of the most rewarded groups in the field of chemical process design, simulation and optimization: Prof. Barton’s group at Department of Chemical Engineering-MIT, will support the distillation, dynamic modelling, simulation, optimization and economic evaluation. In this way, a European Researcher will be trained in a world ranked institute and reintegrate this knowledge back to Europe, raising further his career as the European research area and supporting a sustainable (energy efficient) and competitive solution for an important application.";149337,5;149337,5;FP7-PEOPLE-2009-IOF;/MC-IOF;UNIVERSIDADE DO PORTO;PT;;;"/LIF;/EDU";1;0;0;1;0;0 100061;273292;SOCIALCATH;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-IEF;FP7;Socialism and leftist Catholicism in France and Italy (1956-1972);2012-01-01;2013-12-31;;"'The SOCIALCATH research project deals with the intercultural connection between Socialism and Catholicism in two cases in which this meeting was very evident: the French 'Parti Socialiste Unifié' (PSU) and the Italian 'Partito Socialista Italiano di Unit? Proletaria' (PSIUP). PSU and PSIUP put together Socialists and Catholics who did not accept the main strategy of their respective political families. PSU and PSIUP wanted represent a radically democratic form of modernity, giving great attention to social ferments and to defend all discriminated or under-represented categories: workers, women and young people. PSU and PSIUP were libertarian and they refused the hierarchical structures of a mass party, adopting a fluid organisation totally open to different cultural models. The political relationship between PSU and PSIUP, their ideological exchanges and the contacts between their members have never been explored within a scientific context. The SOCIALCATH project aims to fill this scientific gap, bringing to light many unedited documents. The interdisciplinary approach, the multi-methodological analysis and the comparative nature of the SOCIALCATH project are all new instruments to be used in these arguments. The SOCIALCATH project aims to reach three main objectives: 1. to describe the meeting between opposite cultural areas such as Socialism and Catholicism, in order to support the policies for intercultural dialogue promoted by the EU and other international organisations such as UNESCO. 2. to highlight alternative aspects of Socialist and Catholic cultures, in order to discover the anti-dogmatic spirit of the 60s and its today's inheritance in the collective European conscience. 3. to explore the relationship between the PSU and PSIUP's political class and the new social issues of the 60s (feminism, 'the young' issue, etc.), in order to compare those events with the present attitude of the European leading class towards society and collective issues.'";179048;179048;FP7-PEOPLE-2010-IEF;/MC-IEF;FONDATION NATIONALE DES SCIENCES POLITIQUES;FR;;;"/EMP;/EDU;/NET";1;0;0;1;0;0 103051;299030;LCMVACC;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IEF;FP7;Prophylactic and therapeutic use of recombinant lymphocytic choriomeningitis virus against melanoma;2012-04-01;2014-03-31;;"'Cancer is one of the most common reasons for death of people living in the developed countries. There were an estimated 3.2 million new cases of cancer and 1.7 million deaths in the year 2008 in Europe. Melanoma is a form of skin cancer caused by mutation of melanocytes in the skin. Common cancer therapy is not effective in treatment of metastatic melanoma. The survival rate of patients with this form of the disease is very low, indicating the need for development of new therapeutic options. The proposed research aims towards developing vaccination strategies that can be used for prevention or therapy of melanoma. Recent work in the field of cancer vaccination indicates high potential to improve and prolong the life of the patients. In the proposed research, the use of a new and very safe vaccine vector based on the modified lymphocytic choriomeningitis virus (rLCMV) for fight against cancer will be elucidated. The roll of immune cells to break the normal tolerance of the organism to tumour cells will be investigated and characterised. By conducting this research, not only cancer vaccination will be brought closer to application in patients, but additional insight into the mechanisms underlying immune tolerance against cancer will be gained. Cancer vaccination is a very timely scientific field and progress in this area will be noticed by the general public worldwide. The research will be conducted in the Dermatology Department at the University Hospital of Lausanne, Switzerland. The researcher is from Germany and has been working in the Department of Virology at the Bernhard-Nocht-Institute for Tropical Medicine in Hamburg. By performing the proposed research, the applicant will get additional interdisciplinary training on immunological methods and vaccination strategies. By adding these competencies, he will afterwards be able to establish his own work group focussing on viral pathogenesis and vaccination at a European research institute or university.'";192622,2;192622,2;FP7-PEOPLE-2011-IEF;/MC-IEF;CENTRE HOSPITALIER UNIVERSITAIRE VAUDOIS;CH;;;/SCI;1;0;0;1;0;0 95885;254334;PRESS;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IEF;FP7;Precipitate Elastic Stress States;2010-09-01;2011-08-31;;"I am a Professor in the Department of Physics at the University of Oslo, and I am currently 1 of 6 full time professors at the Norwegian Research Centre of Excellence on the Physics of Geological Processes (PGP), where I am responsible for all its experimental activities. Although there is a wide range of expertise in PGP, there are still limitations to our knowledge, tools and research techniques which must be overcome. The Grenoble complex, where very strong university research teams work alongside leading CNRS laboratories, has most of the capabilities that we lack. I propose to launch an original research project that probes fundamental questions in Gibbs' thermodynamics and is interdisciplinary in it's application to Physics, Earth Science and Materials Science. Recent experimental results from my group contradict theoretical results from the group of Chaouqi Misbah (of Laboratoire de Spectrometrie Physique (LSP) of the University of Joseph Fourier (UJF) in Grenoble) and afford an original and innovative angle on 140 years of theoretical discussions on the thermodynamic theory of non-hydrostatically stressed solids. I propose a 12 month integrated theoretical and experimental project in Grenoble which will use state of the art continuum modeling techniques and high resolution optical and synchrotron X-ray techniques to test 5 bold hypotheses. The goal of the proposed project will be to combine the theoretical and experimental excellence in the Grenoble region with the unique physics/geoscience research at PGP in order to 1) publish two original research papers in top rated physics and geoscience journals, 2) train me in state of the art continuum mechanics modeling methods and high resolution optical and sychrotron X-ray methods, 3) enhance my ability to mange research projects, 4) forge new links between research communities in Grenoble and Oslo and 5) to develop a European research proposal between Oslo and Grenoble.";116373,6;116373,6;FP7-PEOPLE-2009-IEF;/MC-IEF;UNIVERSITE JOSEPH FOURIER GRENOBLE 1;FR;;;"/SCI;/EDU;/ITT";1;0;0;1;0;0 103603;302854;PICengineering;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IEF;FP7;Basal factor engineering and synthetic nucleosomal DNA super-template construction for pre-initiation complex assembly;2012-05-01;2014-04-30;;Initiation of RNA polymerase II (Pol II) transcription is activated by the assembly of preinitiation complex (PIC) onto gene promoters. PIC contains the largest general transcription factor (GTF), TFIID that comprises TATA box-binding protein (TBP). The binding of TBP to TATA promoter is rate-limiting step in PIC assembly and is stabilized by GTFs, TFIIA and TFIIB. TFIID also contains reader domains that recognize specific epigenetic marks in nucleosomes located upstream and downstream of transcription start site. Structural information on the architecture of nucleosomes, DNA, TFIIA, TFIIB and TFIID in this context remains elusive to date limiting our understanding of DNA architecture at promoter site and the interaction of TFIID with epigenetically modified nucleosomes in transcription initiation. The objective of this proposal is to explore this cross-talk by creating a synthetic DNA super-template for PIC assembly containing modified nucleosomes, promoter DNA, TFIIA, TFIIB and TBP. This will be attempted via an international collaborative effort, employing integrated multidisciplinary approach including protein and DNA engineering and their supramolecular assembly combined with chemical cross-linking. This template will be analyzed with and without highly purified, fully recombinant TFIID (sub)complexes through a multi-resolution structural approach with X-ray crystallography, electron microscopy and small angle X-ray scattering techniques. This methodology will be useful to explore interactions of similar complexity involving other chromatin regulatory factors, thereby extending the horizon of transcription research or general multi-protein complex research, which is at the forefront of contemporary molecular biology. The interdisciplinary nature of this project promises to contribute to the applicant’s career development by diversifying and advancing her competencies and refining her skills ultimately guiding her towards a position of independent leadership.;269096,4;269096,4;FP7-PEOPLE-2011-IEF;/MC-IEF;EUROPEAN MOLECULAR BIOLOGY LABORATORY;DE;;;/SCI;1;0;0;1;0;0 103237;301369;CHESS;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IEF;FP7;Block Copolymers for High Efficient Solar Cells with novel Structures;2012-04-01;2014-03-31;;'This IEF project aims to address both hurdles apparent in the fabrication of Bulk Heterojunction Organic Photovoltaics (OPVs), i.e. the tailoring of the domain size to be close to the excitonic diffusion length and the stability of the blend morphology, through a wise incorporation of block copolymers in the blend that forms the active layer of OPVs. My target is to fabricate highly efficient solar cells with enhanced morphological stability and prolonged lifetimes, applying process techniques that can be easily adopted by industry. The self-assembly properties of block copolymers as well as their ability to form well controlled nanostructures and to act as compatibilizers in the blends of the respective homopolymers will be exploited to form stable nanomorphologies with optimum domain size, according to the specifications required for OPV applications. An integrated study will be conducted, starting from fundamental research on the polymer physics of the ternary system: rod-like homopolymer A – homopolymer B – rod-coil copolymer A-B. Next, the blends which exhibit the desirable co-continuous morphological characteristics will be incorporated into OPVs and the device performance and stability will be studied and optimized. Finally, I am going to apply the concepts of graphoepitaxy, a novel technique applied for the fabrication of well-ordered arrays of block copolymers, in the construction of OPVs, in an effort to realize the ideal interpenetrating structure proposed and achieve even higher efficiencies through a precise control of the nanostructure. The scope of the proposed research lies on the cutting-edge field of organic electronics (OE), which is of strategic importance for the competitiveness and the advancement of the socio-economic conditions of the European Union. The skills acquired during my studies will be complemented by the extensive experience of the host institute on OE to assure a successful accomplishment of this fully interdisciplinary project.';193594,8;193594,8;FP7-PEOPLE-2011-IEF;/MC-IEF;INSTITUT POLYTECHNIQUE DE BORDEAUX;FR;;;/SCI;1;0;0;1;0;0 88309;219412;MICROPADS;ONG;FP7-PEOPLE;PEOPLE-2007-2-1.IEF;FP7;New Micro-Robotic Systems featuring Piezoelectric Adaptive MicroStructures for Sensing and Actuating, with Associated Embedded Control;2008-07-02;2010-07-01;;Adaptronics is a state of the art interdisciplinary area of research. It unites broad principles of structural mechanics, advanced material science (notably piezoelectric), actuation and sensing elements and embedded control technology. Adaptive systems are autonomous self-regulating mechanisms, able to adapt themselves over variations of environmental conditions. Innovative adaptronic systems intend to extend the framework of the possibilities with the development of new products within almost all ranges of the industry. The project focuses on one of the most promising applications of piezoelectric adaptive systems: microrobotics and micro-assembling systems for micrometric components. These systems require a very strict performance such as nanometer resolutions, millisecond response time etc. and the use of precise sensors is indispensable. But, until now, there does not exist a “perfect” sensor neither in industry nor in research, with convenient sizes, precision and dynamics for microrobotic applications. It appears very interesting and innovative to develop centi/millimeter active structures integrating on the same piezoelectric material both the actuating and the sensing functions with embedded control. Such smart systems could be designated as cost-effective, compact and multi-functional, since they handle carrying, sensory and actuating tasks at the same time. The subject of the proposed research is multi-disciplinary and seeks a series of specific approaches for improving the overall microrobotic performance. As described in the proposal, it touches several areas: mathematical modeling, multiphysics design, microtechnology, theory of automatic control and software development, according to host institution expertise and researcher career.;171600,91;171600,91;FP7-PEOPLE-2007-2-1-IEF;/MC-IEF;UNIVERSITE DE FRANCHE-COMTE;FR;;;"/SCI;/EDU";1;0;0;1;0;0 94354;244147;MEDIAACT;ONG;FP7-SSH;SSH-2009-5.1.1.;FP7;Media Accountability and Transparency in Europe;2010-02-01;2013-07-31;http://www.mediaact.eu/;In this proposal, we suggest a comparative European research project on media accountability systems in EU member states as indicators for media pluralism in Europe. The project will analyze the development and impact of established media accountability systems (i.e. press councils, ethics codes) as well as new media accountability systems emerging in the Internet (i.e. media criticism in blogs). The main goals of this research project are • to investigate the quantity and quality of media accountability systems as prerequisites for pluralistic debates about media independence in times of growing media concentration, • to compare the impact of established and innovative media accountability systems online on different media systems and journalism cultures in Europe and beyond, • to develop policy recommendation for EU media lawmakers, as well as incentives for media professionals and media users alike to actively engage in media accountability systems. The project will be a joint interdisciplinary effort of a team of 11 partners form Eastern and Western Europe as well as one partner from the Arab World (members of the European-Mediterranean partnership), using a multi-method approach (survey, desk studies and expert interviews) for the analysis. Since the project aims at analyzing the potential of media accountability systems for media accountability and transparency, it will carry the acronym MediaAcT.;1741566,4;1468811;FP7-SSH-2009-A;/CP-FP;ERICH-BROST INSTITUT FUR JOURNALISMUS IN EUROPA GEMEINNUTZIGE GESELLSCHAFT MIT BESCHRANKTER HAFTUNG EBI GMBH;DE;"TARTU ULIKOOL;UNIVERSITATEA DIN BUCURESTI;UNIWERSYTET WROCLAWSKI;STICHTING FONTYS;TAMPEREEN YLIOPISTO;UNIVERSITE PARIS II PANTHEON ASSAS;INSTITUT D'ETUDES POLITIQUES DE TOULOUSE;UNIVERSITY OF THE WEST OF ENGLAND, BRISTOL;UNIVERSITA DELLA SVIZZERA ITALIANA;MEDIENHAUS WIEN FORSCHUNG UND WEITERBILDUNG GmbH;UNIVERSITA DEGLI STUDI DI MILANO;THE MEDIAWISE TRUST";"EE;RO;PL;NL;FI;FR;UK;CH;AT;IT";"/ECO;/SOC;/INF";1;0;0;1;0;0 89340;212545;AEGOS;ONG;FP7-ENVIRONMENT;ENV.2007.4.1.4.1.;FP7;African-European Georesources Observation System;2008-12-01;2011-11-30;http://www.aegos-project.org;Africa, the largest single component of the African Caribbean Pacific (ACP) Group of States, despite its huge potential for development through both human and georesources, suffers in many places from poverty and underdevelopment. The sustainable use of its resources is a key issue, not only for development of the African countries, but also for the world’s future. Over the coming decades, these issues are likely to play an ever-increasing role due to the world’s growing population, rapid urban development and the rising demand for better infrastructure and services. The sustainable use of georesources requires a knowledge based on data, information and expertise. Thus, the availability, traceability, accessibility and processing using GIS technologies of heterogeneous data from multiple sources is essential. Such processing requires a qualified and experienced personnel and the definition of strategies for capacity building and training. In view of this situation, a recognised need has emerged for a shared, distributed, Internet-linked georesources observation system, based on open standards and interoperability developments, as a contribution to the sustainable development of African countries. The Support Action is the preparatory phase needed to design the African-European Georesource Observation System (AEGOS) capable of hosting and providing access to Africa’s geological resources, including groundwater, energy, raw materials and mineral resources. Its objectives are to define: i) operational procedures for data management (Spatial Data Infrastructure, metadata and data specification), ii) user-oriented products and services including the preparation of innovative spin off projects based on AEGOS and an evaluation of the input of Interoperability and interdisciplinary in support of GEOSS iii) the African- European partner network, iv) a geoscience contribution to GEOSS, in the context of INSPIRE;2422557,6;1930996;FP7-ENV-2007-1;/CSA-SA;BUREAU DE RECHERCHES GEOLOGIQUES ET MINIERES;FR;"GEOLOGIAN TUTKIMUSKESKUS;The Southern and Eastern African Mineral centre;INSTITUTO NACIONAL DE ENGENHARIA, TECNOLOGIA E INOVACAO;Geological Survey and Mines;Minist?re des Mines et de l'Industrie;NEDERLANDSE ORGANISATIE VOOR TOEGEPAST NATUURWETENSCHAPPELIJK ONDERZOEK TNO;Geological Survey of Ethiopia;UNIVERSITY OF DAR ES SALAAM;INSTITUT ROYAL DES SCIENCES NATURELLES DE BELGIQUE;BUNDESANSTALT FUER GEOWISSENSCHAFTEN UND ROHSTOFFE;Minist?re des Mines et de la Géologie;UNION ECONOMIQUE ET MONETAIRE OUEST AFRICAINE;CESKA GEOLOGICKA SLUZBA;PANSTWOWY INSTYTUT GEOLOGICZNY - PANSTWOWY INSTYTUT BADAWCZY;BEAK CONSULTANTS GMBH;UNIVERSITY OF ZAMBIA;INSTITUT DE RECHERCHE POUR LE DEVELOPPEMENT;Geological Survey Department;CENTRE INTERNATIONAL POUR LA FORMATION ET LES ECHANGES EN GEOSCIENCES;COUNCIL FOR GEOSCIENCE;NATURAL ENVIRONMENT RESEARCH COUNCIL;JRC -JOINT RESEARCH CENTRE- EUROPEAN COMMISSION";"FI;TZ;PT;UG;SN;NL;ET;BE;DE;GN;BF;CZ;PL;ZM;FR;GH;ZA;UK";/ENV;1;0;0;1;0;0 97081;265170;ERMITAGE;ONG;FP7-ENVIRONMENT;ENV.2010.4.2.1-1;FP7;Enhancing Robustness and Model Integration for The Assessment of Global Environmental Change;2010-12-01;2013-11-30;http://ermitage.cs.man.ac.uk/;The development of interdisciplinary modelling tools and platforms to address the interactions between natural and socio-economic systems is an active research area in Europe. Nevertheless, notable gaps still exist in modelling capabilities, in particular, very little progress has been made to date in the direct coupling of models that resolve the spatial distribution of climate change with sectorally and regionally resolved economic models. Interactive couplings between climate and impact models are relatively underdeveloped. Likewise, the coupling of detailed economic models with impact and adaptation models is still at a relatively early stage. Finally, a coherent assessment of uncertainty is completely lacking in overall integrated assessments. The sustainability of agriculture and land-use policies and practices including water availability and the sustainability of climate policies that rely on high shares of bioenergy are critical applications that demand a spatially resolved representation of global environmental change including feedbacks between natural and socio-economic forces. ERMITAGE proposes to improve and extend existing modular frameworks for the coupling of intermediate complexity models of the natural and socio-economic systems to address the issues cited above. The resulting integrated assessment framework models will be applied to the analysis of post-2012 climate initiatives taking into account uncertainties and regional conflicts of interest in a coordinated way, propagating the analysis of uncertainty from climate simulation through to policy analysis, focusing particularly on the sustainability of agriculture, bioenergy and water resources.;4355313,77;3383455,55;FP7-ENV-2010;/CP-FP;THE OPEN UNIVERSITY;UK;"UNIVERSITY OF EAST ANGLIA;THE UNIVERSITY OF MANCHESTER;ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE;POTSDAM INSTITUT FUER KLIMAFOLGENFORSCHUNG;SCIENCE AND TECHNOLOGY FACILITIES COUNCIL;ORDECSYS SARL;ENERIS Environment Energy Consultants S.L.";"UK;CH;DE;ES";/ENV;1;0;0;1;0;0 99403;273824;GenderMassCareer;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-IEF;FP7;Mass Career Customization -a flexible career approach : effects on women's career advancement and wellbeing;2011-10-01;2013-09-30;;During my IEF I will investigate on the effects of a new innovative career tool on the career advancement of women inside a multinational Accountancy firm. The overall objective is to examine how organisations by the use of more flexible career models can create inclusive organisational cultures that promote equal treatment and health and well-being among their female workforce. In this regard, I follow an important request of the EU – the promotion of gender equality and employability. To address this question I will apply an interdisciplinary approach using theories and methods from the field of organisational behaviour, applied psychology, sociology and management. Data originates from an existing dataset (n= 1043) that will be complemented by (1) a follow up employee survey and (2) a survey directed to employees’ supervisor. Data is obtained in two points of time in order to observe changes in objective and subjective careers success and other individual outcomes such as wellbeing, job satisfaction, career satisfaction, work-family conflict, stress, turnover intentions. Furthermore, objective data on career advancement of women in comparison to men will be derived from company data (e.g. entry assessments, performance ratings, promotions, salary level data, and turnover rates). The project will be carried out in cooperation with an industry-academic partnership between the Amsterdam Center for Career Research (ACCR), VU (Vrije Universiteit) Amsterdam and a multinational Accountancy firm in the Netherlands.;169485,6;169485,6;FP7-PEOPLE-2010-IEF;/MC-IEF;STICHTING VU;NL;VERENIGING VOOR CHRISTELIJK HOGER ONDERWIJS WETENSCHAPPELIJK ONDERZOEK EN PATIENTENZORG;NL;"/EMP;/EDU;/NET";1;0;0;1;0;0 92117;239318;LASERGLASS;ONG;FP7-PEOPLE;PEOPLE-2007-2-2.ERG;FP7;Laser technologies in the analysis, conservation and restoration of historic stained glass windows;2009-05-25;2012-05-24;;"Protection and conservation of historic stained glass windows is one of the most important, urging challenges for the European Cultural Heritage. Through many ages these valuable objects have been exposed to various atmospheric conditions: water, sunlight, wind, temperature changes; biological activity, human devastation and a deep air pollution. Those damaging factors caused irreversible changes in the glass structure and corroded the glass bulk. In the typical historic stained glasses the bulk glass is covered with a protective silica gel layer and with a superficial layers (corrosion crust, dirt, polymers and micro-organisms). Due to the lack of the homogeneity and the complexity of problems occurring on the corroded glass, the conservation of stained glass meets important difficulties in the chemical analysis of the bulk glass composition and in the removing of corrosion and dirt layers. The classical renovation methods employs chemical or mechanical treatments which present many disadvantages. As the alternative method, the laser cleaning was proposed. This project aims to realize the complex study on the interaction between laser irradiation and a corroded glass, followed by the construction of the laser cleaning station, dedicated to stained glass windows, equipped with LIBS and LIF. To prove the effectiveness of the developed system, the entire stained glass window panels from XVII century will be analyzed and cleaned. In the following, the obtained cleaning results will be compared with ones obtained by the traditional methods. Additionally the project will employ advanced, modern surface analysis techniques as SEM/EDX, AFM and Optical Coherence Tomography. In the evaluation step the physical, chemical, biological and climatic studies will be carry out to investigate whether laser cleaning is safe for the historical glass. In all parts of the research the stress will be put on the interdisciplinary cooperation between scientists and art conservators.";45000;45000;FP7-PEOPLE-ERG-2008;/MC-ERG;Academy of Fine Arts;PL;;;"/SCI;/EDU";1;0;0;1;0;0 102921;298603;Histone Demethylases;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IEF;FP7;A Chemical Genetics Approach towards Cancer Therapy Targeting Histone Demethylases;2012-03-01;2014-02-28;;"Cancer is one of the most common causes of death in the EU. The disease is characterized by aberrant gene activity in certain cells. Even today, cancer therapy is little focused, which is reflected by severe side effects. Consequently, there is a need for novel and better tolerated therapies. In this proposal an approach to validate a new class of enzymes as targets for cancer therapy is presented. In the cell nucleus, DNA is bound to special proteins, called histones, which play key roles in gene regulation. Histones can be dynamically modified with special marker groups, which allows the control of gene expression without alteration of the DNA itself. Specifically, it is intended to inhibit histone demethylases, specialized enzymes which remove certain marker groups (methyl groups) from histones, which results in gene silencing or activation. Histone demethylases are known to be upregulated in certain cancers and are therefore promising candidates for pharmacological cancer therapy. Ideally, small molecule inhibitors will inhibit cancer growth and might even be able to restore the normal genetic program of a cell. During the study specific small molecule-enzyme pairs will be created, which allows the study of a single enzyme among very similar ones. This chemical genetics approach encompasses the mutation of the enzyme and the synthesis of specifically tailored small molecules. The properties of the enzyme-inhibitor pairs will be evaluated by in vitro assays and crystallization. Afterwards the compounds will be used to decipher the role of the histone demethylase in cell culture models by microarray methods and RNA sequencing. The study will be very interdisciplinary and encompass chemical synthesis, biochemistry, cell biology and structural biology.";200371,8;200371,8;FP7-PEOPLE-2011-IEF;/MC-IEF;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;UK;;;/SCI;1;0;0;1;0;0 96489;252343;ARSEEDAS;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IOF;FP7;Alternative splicing of NADPH-Oxidases as a mechanism for seed dormancy regulation;2011-04-27;2014-04-26;;This project brings together a top-class, young researcher from Germany, Kerstin Müller with two world-leading experts on complementary aspects of seed biology: Prof. Mike Holdsworth at Nottingham University UK and Prof. Allison Kermode at Simon Fraser University, Burnaby, Canada. The project will work on the very active and timely field of alternative splicing during seed after-ripening and its connection with the plant hormone abscisic acid (ABA). Seeds can enter a state of dormancy in which they fail to germinate under ideal conditions. Dormancy can be broken by after-ripening (air-dry storage at room temperature). The mechanisms underlying this economically and environmentally important process are not understood. Alternative mRNA splicing might play a role in dormancy regulation in seeds: it would be a flexible and fast way of reacting to changes in the environment. The superoxide-producing NADPH-Oxidase AtrbohB is alternatively spliced in seeds depending on developmental status and the presence of ABA, and atrbohB mutants fail to after-ripen. The proposed interdisciplinary project will investigate mRNA-splice forms and superoxide production by rbohs in Arabidopsis and two other selected species during after-ripening and germination and focus on the the relation between ABA signalling, rbohs and alternative splicing in Arabidopsis seeds. This research will uncover novel findings on after-ripening and alternative splicing which will be published in international journals and at conferences. Long term collaboration will be set up between the Simon Fraser University and Nottingham University. Kerstin Müller will gain valuable experience in both state-of-the-art laboratory techniques as well as a range of complimentary skills whilst working in Canada, from which Nottingham University and the European Research Area in general will benefit both by transfer of knowledge and by promoting the Europe-based career of a promising young scientist.;235690,2;235690,2;FP7-PEOPLE-2009-IOF;/MC-IOF;THE UNIVERSITY OF NOTTINGHAM;UK;;;"/LIF;/EDU";1;0;0;1;0;0 95837;244035;SPIRAL;ONG;FP7-ENVIRONMENT;ENV.2009.4.2.3.2;FP7;SCIENCE-POLICY INTERFACES FOR BIODIVERSITY: RESEARCH, ACTION, AND LEARNING;2010-05-01;2013-11-30;;'SPIRAL aims to enhance the connectivity between biodiversity research and policy making. Although conservation and the sustainable use of biodiversity are fundamental requisites of human well-being, the biodiversity issue raises unprecedented challenges regarding science-policy interfaces. The project proposes state of the art interdisciplinary research on science-policy interfaces for sustainability governance at the theoretical, methodological and practical levels. This will support the design, implementation and operation of the 'real-life' institutional designs that are currently emerging to interface biodiversity research and sustainability policy. The project will also provide an opportunity for the main actual or potential policy actors and stakeholders in biodiversity science-policy interfaces to learn, share experiences and network. SPIRAL will deliver a series of practical products for the benefit of users involved in interfaces, including workshops, networking opportunities, handbooks, policy briefs, targeted synthetic reports, an internet pilot platform, and a dedicated website. Overall this will allow scientists, policy-makers and other stakeholders to capitalise on a better understanding of science-policy interfaces and implement better practices.';1737134;1349291,75;FP7-ENV-2009-1;/CP-FP;NATURAL ENVIRONMENT RESEARCH COUNCIL;UK;"HELSINGIN YLIOPISTO;UNIVERSITATEA DIN BUCURESTI;Median SCP;STICHTING NIOZ, KONINKLIJK NEDERLANDS INSTITUUT VOOR ONDERZOEK DER ZEE;HELMHOLTZ-ZENTRUM FUER UMWELTFORSCHUNG GMBH - UFZ;CENTRE DE COOPERATION INTERNATIONALE EN RECHERCHE AGRONOMIQUE POUR LEDEVELOPPEMENT - C.I.R.A.D. EPIC;THE MACAULAY LAND USE RESEARCH INSTITUTE;VLAAMS GEWEST";"FI;RO;ES;NL;DE;FR;UK;BE";"/ENV;/SDT;/POL";1;0;0;1;0;0 93038;235447;ERASYSBIO+;ONG;FP7-GA;ERANET.2008.2;FP7;The consolidation of systems biology research – stimulating the widespread adoption of systems approaches in biomedicine, biotechnology, and agri-food;2008-10-01;2013-09-30;;Systems biology is still considered a young discipline in the field of life sciences. It integrates mathematics, chemistry, physics, informatics, engineering and other fields in biological research. The fragmentation of the discipline concerns all levels of the field: (i) It confronts researchers with a new combination of knowledge, methods, skills and expertise from different disciplines. (ii) It challenges funders overcome obstacles hindering cross organisational funding - across national boarders. (iii) It dares policymakers set goals outside the limits of preconceived structures. It is the interdisciplinary that makes collaboration imperative - on all levels. Therefore the ERASysBio\ partners firmly believe that systems biology offers the ideal vehicle to implement pan-European collaboration in order to overcome the still success limiting fragmentation within systems biology. The aim of this proposal is to implement a large transnational call enabling transnational, collaborative research projects in systems biology research. The funding organisations represented by this consortium are aiming to i.) jointly pave the way for systems biology research to interact outside the boundaries set by national regulations, ii.) widen the landscape beyond that of well established groups and contribute to integrating groups from regions where the systems approach and its funding are only just emerging. The ERA-NET-Plus instrument is the only instrument to effectively combine national and European funding efforts in a efforts in a joint funding measure achieve the abovementioned ambitious goals. .;24004209,8;5500000;FP7-ERANET-2008-RTD;/CSA-ERA-Plus;FORSCHUNGSZENTRUM JULICH GMBH;DE;"MINISTERIO DE CIENCIA E INNOVACION;BUNDESMINISTERIUM FUER BILDUNG UND FORSCHUNG;ZORGONDERZOEK NEDERLAND ZON;MINISTERIO DE ECONOMIA, INDUSTRIA Y COMPETITIVIDAD;SUOMEN AKATEMIA;ISRAEL SCIENCE FOUNDATION;BIOTECHNOLOGY AND BIOLOGICAL SCIENCES RESEARCH COUNCIL;FONDS NATIONAL DE LA RECHERCHE;MINISTRSTVO ZA VISOKO SOLSTVO, ZNANOST IN TEHNOLOGIJO;AGENCE NATIONALE DE LA RECHERCHE;BUNDESMINISTERIUM FUER DIGITALISIERUNG UND WIRTSCHAFTSSTANDORT;Ministrstvo za izobrazevanje, znanost in sport";"ES;DE;NL;FI;IL;UK;LU;SI;FR;AT";"/SCI;/COO";1;0;0;1;0;0 92545;235649;VIRUS ENTRY;ONG;FP7-PEOPLE;FP7-PEOPLE-ITN-2008;FP7;Molecular Mechanisms of Cell Entry of Enveloped Viruses;2009-10-01;2013-09-30;;Virus infections are a major cause of diseases and death among men and animals. The recent outbreak of SARS and the danger that an avian influenza virus may become pandemic, have clearly shown that members of any virus family can potentially turn into a pathogen. To combat virus infection and propagation, systematic and comprehensive studies both on viral components mediating virus-cell interactions, and on the cell biology behind virus entry are necessary. Our network, teaming academic and industrial groups, is aimed at undertaking an interdisciplinary effort to reveal the diversity of pathways and associated molecular mechanisms of cell entry of enveloped viruses. Research by experimental and theoretical approaches will be directed towards the identification of cellular receptors and of viral fusion proteins responsible for interaction with host cells. Among topics are folding, three-dimensional structure and conformational changes of viral fusion proteins as well as virus triggered signalling cascades in cells. Biophysical approaches will unravel the relationship between energetics of conformational changes of viral proteins and membrane bending and fusion. Together with industrial partners the project will identify potential targets for designed drug development, and will develop virus protein coated nanoparticles as new biotechnological and medical tools. The groups have complementary expertise at the highest standard in all required techniques of virology, molecular and cellular biology, biochemistry, proteomics, structural biology, theoretical and experimental biophysics. A challenging research and training environment in an international setting will provide young scientists with a network wide research-oriented training devoted to the specific aspects of virus entry and to structuring of industry projects and commercial exploitation of results, and a local training in soft skills and basic complementary education adapted to the personal needs.;3844983;3844983;FP7-PEOPLE-ITN-2008;/MC-ITN;HUMBOLDT-UNIVERSITAET ZU BERLIN;DE;"INSTITUT PASTEUR;EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH;TEL AVIV UNIVERSITY;KAROLINSKA INSTITUTET;UNIVERSITEIT UTRECHT;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FREIE UNIVERSITAET BERLIN;Capsulution Pharma AG";"FR;CH;IL;SE;NL;DE";"/SCI;/EDU";1;0;0;1;0;0 104385;300444;PROAFRI;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IEF;FP7;Protests in Sub-Saharan African countries;2012-09-01;2014-12-15;;"'This project aims to study mobilization in sub-Saharan African countries -with a focus on Nigeria and Zimbabwe- by investigating protest activities between the year 1995 and 2010. By articulating the social movement literature with African studies, the research aims to analyze the impact of the political context and the organizational structure on mobilization in such countries. In addition, it proposes to study the impact of a repressive political context on the organizational structure sustaining mobilization. Empirically, the research will first explore mobilization in various sub-Saharan African countries by using existing public opinion surveys (Afrobarometer Survey Series Data) containing information on individual engagement in protests and public demonstrations. To understand the impact of a repressive context on the organizational structure, it will then analyze protest events and actors involved in protests in Nigeria and Zimbabwe, both classified as repressive countries by international indexes. By specifically focusing on mobilization around the oil-related issues in the Niger Delta, in-depth interviews with main organizational actors will clarify the specific organizational resources necessary for the development of protests in a repressive context. Analyses of these data will privilege a mixed-method approach and will be elaborated through classical inferential statistics and qualitative techniques. The project is relevant for the Work Programme as it proposes a genuine mobility within the ERA and it promotes interdisciplinarity and intersectoriality, thus strengthening exchanges and networks among scientific communities. In addition, it aims to attract the interests by non-specialists on issues relevant for European policies.'";192622,2;192622,2;FP7-PEOPLE-2011-IEF;/MC-IEF;UNIVERSITE DE GENEVE;CH;;;/SCI;1;0;0;1;0;0 102693;299280;HiPEP;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IEF;FP7;Highly Functional Polypeptides;2012-05-01;2014-04-30;;"Peptides are nature’s expression language and as such perform vital roles in living organisms. They are highly functional and produced naturally with a precision that is unprecedented in synthetic materials such as polymers. Synthetic polypeptides present a promising alternative as they combine the accessibility of synthetic polymers with functionality and biocompatibility of natural peptides. They are thus ideally suited as a new (commercial) renewable and sustainable polymer materials platform if some practical hurdles can be overcome. In this project, new routes for the synthesis of polypeptides will be explored that are inexpensive, scalable and reproducible and allow the tuning of polypeptide properties by copolymerisation. While the approach to be taken is generic, our efforts will focus on the synthesis of Glatiramer. Glatiramer is a commercial product that is currently synthesised by ring opening polymerisation in an uncontrolled fashion, yielding a random copolymer of four amino acids. By improving our understanding of the reaction kinetics, we are aiming to gain a better control over the polymerisation and prepare well-defined Glatiramer-like polypeptides. Subsequently a combinatorial library will be prepared and the various Glatiramer-like polypeptides will be screened for biologically activity towards multiple sclerosis. This is a highly interdisciplinary project at the interface of polymer chemistry, combinatorial chemistry and life science. The applicant’s diverse experience makes him an ideal match for this work. The project also brings together academics from world class institutions with complementary expertise that provides a unique environment for the applicant to develop his skills and accelerate his academic career.";191675,4;191675,4;FP7-PEOPLE-2011-IEF;/MC-IEF;TECHNISCHE UNIVERSITEIT EINDHOVEN;NL;;;/SCI;1;0;0;1;0;0 92455;238363;CONTACT;ONG;FP7-PEOPLE;FP7-PEOPLE-ITN-2008;FP7;Marie Curie Initial Training Network for the tailored supply-chain development of the mechanical and electrical properties of CNT-filled composites;2009-10-01;2014-03-31;;The EU is currently directing intensive research efforts into nanotechnology. Carbon Nanotubes (CNTs), with the electrical conductivity of copper and an E-modulus 10 times greater than steel, are one of the most promising developments, enabling the creation of materials with revolutionary characteristics. The commercial potential is huge, but only a fraction of the possible applications have reached the market. Collaboration is needed between academia and industry, so that processes developed on a laboratory scale can be upscaled for industrial application. This consortium, which achieves an optimal balance between academia and industry (50:50) in the field of CNTs, and which spans the entire value added chain from CNT synthesis to implementation in saleable products, is convinced that the 576 person-months spent on this project will achieve this aim. 18 researchers, in unique collaboration with cutting-edge teams, will work to overcome recognised limitations in the state of the art, including the adjustment of CNT surface properties, CNT dispersion in thermosets and thermoplastics, reliable analysis and characterisation. Carefully structured networking will ensure the efficient exchange of knowledge between researchers, the partners and society. Focus on 3 specific end-use applications (construction, wind blades, electrodes) will ensure quantifiable and tangible results. The predicted growth of nanotechnology can only be sustained through the education of scientists. The vast teaching experience of the partners will ensure a high-quality training program. Through mentoring by world-class researchers, conferences, courses ranging from leadership for women to presentation skills, interdisciplinary and intersectoral experience, the appointed researchers will gain scientific know-how and the complementary skills necessary to exploit it. The S&T and training elements will combine to form a structured program, adaptable to each researcher's needs.;3477181;3477181;FP7-PEOPLE-ITN-2008;/MC-ITN;FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.;DE;"UNIVERSIDADE DO MINHO;PROMOLDING BV;Polymaterials AG;TTY-SAATIO;AIMPLAS - ASOCIACION DE INVESTIGACION DE MATERIALES PLASTICOS Y CONEXAS;BAYER TECHNOLOGY SERVICES GMBH;MAGYAR TUDOMANYOS AKADEMIA TERMESZETTUDOMANYI KUTATOKOZPONT;Amroy Europe Oy;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;MUSZAKI FIZIKAI ES ANYAGTUDOMANYI KUTATOINTEZET - MAGYAR TUDOMANYOS AKADEMIA;ACCIONA CONSTRUCCION SA";"PT;NL;DE;FI;ES;HU;UK";"/SCI;/EDU";1;0;0;1;0;0 95882;253103;BRAIN IRON IN ADHD;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IOF;FP7;BRAIN IRON LEVELS IN CHILDREN WITH ATTENTION-DEFICIT/HYPERACTIVITY DISORDER: AN IMAGING AND NEUROPHYSIOLOGICAL STUDY;2010-09-01;2013-08-31;;The applicant is a child psychiatrist whose overall research objective is to understand the etiopathophysiology of common childhood mental disorders in order to identify more effective treatment and preventive strategies. The proposal is designed to provide the applicant with advanced interdisciplinary skills in brain imaging and neurophysiology. This will be necessary for the success of the proposed research as well as of future innovative projects, supporting the transition from mentored to independent researcher. The project aims to gain insight into the etiopathophysiology of Attention-Deficit/Hyperactivity Disorder (ADHD), one of the most common and impairing childhood mental disorders. Current ADHD treatment is symptomatic, not curative. Treatments targeting etiopathophysiological mechanisms may provide specific curative action. Preliminary data by the applicant’s group suggest that iron deficiency (ID) is a possible etiopathophysiological candidate in ADHD. The proposed research aims to extend these results comparing brain iron levels, estimated by a novel imaging approach (magnetic field correlation), in 20 children with ADHD and 20 healthy controls, and correlating them with measures of functional connectivity. Moreover, the unexplored correlation between brain iron and parameters from electroencephalogram, polysomnogram, and event-related potentials will be assessed in an additional sample of 20 children with ADHD. The project includes specific training in “Translational Developmental Neuroscience,” with a focus on brain imaging, at the Institute for Pediatric Neuroscience, New York University, NY, and training in neurophysiology at the Child Neuropsychiatry Unit, Verona University, Italy. The expected results have the potential to confirm the role of ID in ADHD, providing a strong rationale for large trials of iron supplementation. Considering the low cost of iron therapy and the high prevalence of ADHD, the proposal exhibits high public health relevance;239604,7;239604,7;FP7-PEOPLE-2009-IOF;/MC-IOF;UNIVERSITA DEGLI STUDI DI VERONA;IT;;;"/LIF;/EDU";1;0;0;1;0;0 102615;300718;CONOTOX;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IIF;FP7;Functional characterization of neuroactive toxins using an engineered bacterial type-III secretion system;2012-07-01;2014-06-30;;"Toxins occur in a broad diversity in nature and are produced by a wide array of organisms, including spiders, snails, or plants. Conotoxins are a class of toxins that are synthesized in the venom duct of the marine cone snail, genus Conus. The venom of each Conus species is composed of 100 different toxins that rapidly affect the prey organism at multiple targets. The majority of toxins target ligand-gated or voltage-gated ion channels. Each neuroactive peptide of the venom is highly specific for an individual channel isoform. The applicant proposes to develop in an interdisciplinary approach engineered bacteria that export neuroactive peptides and proteins into the surrounding media, readily available for subsequent characterization. The applicant will utilize the powerful flagellar type-III secretion system of Salmonella enterica for the expression and secretion of recombinant neuroactive peptides. The flagellar-specific type-III secretion apparatus selectively exports substrate proteins at a rate up to 10,000 amino acid residues per second and can be readily manipulated by genetic methods. The applicant will create a Salmonella peptide library based on cDNA isolated from the venom duct of cone snails and use the type-III secretion system as an export shuttle to transport non-flagellar peptides into the surrounding media. The media supernatant or (partially) purified peptides will be analyzed for neurotoxic activity by imaging cellular calcium levels of dorsal root ganglia cells. This innovative approach for the rapid purification of neuroactive compounds using secretion via the well-characterized flagellar type-III secretion apparatus will allow to identify and characterize novel toxins with distinct target specificity. Due to their unique mode of action and their ability to discriminate between different members of a large ion channel family, these toxins have an immense potential for neurobiological research and novel diagnostic or therapeutic applications.";184709,4;184709,4;FP7-PEOPLE-2011-IIF;/MC-IIF;UNIVERSITE DE FRIBOURG;CH;;;/SCI;1;0;0;1;0;0 95958;251173;VIOLEX;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IEF;FP7;Violence Expressed - a comparative study of testimonies of violence among Kurdish activists;2011-01-15;2013-01-14;;"Most people living in conflict areas have experienced armed incidents, poverty, displacement, as well as witnessed torture and killings. However, only certain forms of suffering are publicly acknowledged and may lead to prestige and a strengthened social position within a community, or grant political asylum in the country of refuge. Expressions of suffering and pain are therefore seldom the mere expressions of personal suffering as they are often integrated into a standardized discourse of victimhood and heroism. Taking the two decades of conflict between the Kurdish Workers Party PKK and the Turkish State as point of departure, this projects elaborates on the effects such standardization or silencing of violent experience have on the processing of violent experience – for the individual and the social community at large. Grounded in the anthropology of violence, and based on a two years comparative research in Turkey and Denmark, this multisited and interdisciplinary research aims at understanding how expressions of violence are determined and influenced by social processes such as nationalist discourses, ongoing conflict and migration. Suffering that has no place within a public discourse, is silenced, the body often being the last resort to express the unspeakable. How then do individuals cope with their pain that has been politicized, publicized and collectivized; what happens, when suffering is regarded illegitime, or a sign for weakness and shame? An understanding of these mechanisms is crucial to better understand the violent dynamics in post-conflict societies, as well as to assess difficulties in integration of traumatized refugees. Insight in how violence is understood, coped with and expressed is thus an essential part of assessing and preventing violence in the first place.";207541;207541;FP7-PEOPLE-2009-IEF;/MC-IEF;REHABILITERINGS-OG FORSKNINGSCENTRET FOR TORTUROFRE FORENING;DK;;;"/SCI;/EDU;/ITT";1;0;0;1;0;0 95834;263897;DYNOMIWAS;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-RG;FP7;DYNAMICS OF THE ORGANIC MATTER AND THE MICROBIAL COMMUNITY RELATED TO ITS CYCLING IN ARID AREAS. INVOLVEMENT OF AMENDMENTS BASED ON ORGANIC WASTES;2010-09-01;2013-08-31;;"Microorganisms are responsible for organic carbon mineralization and sequestration in soil, and these processes play a key role in ecosystem sustainability. However, despite the fact that several studies have shown how organic amendments can be used to recover desertified soils, the information regarding the microbial key players and carbon sequestration processes is limited for these areas. The general objective of this proposal is to study the dynamics of organic matter and the function of the microbial community associated with its turnover in desert areas. This proposal includes interdisciplinary aspects that will enrich the knowledge of the fellow and host institution with novel results. We will combine cut-off technologies based on chemical (C analysis), microbiological (microbial activity and biomass), biochemical (enzyme activity and catabolic potential), proteomic (native and non-native based proteomics from organic wastes and soils) and molecular methods (clone libraries, DGGE) to open the “black box” of the soil microbial community related to C transformation in arid and semiarid soils. Several activities are organized: i) Selection of soils with different levels of degradation, ii) evaluation of the addition of new organic materials (sludges, composts, charcoals) in soil microbiological quality; ii) identification of the main physical and chemical carbon sinks; iv) changes in the microbial community structure of soil organic amendment; v) transformations of organic molecules by the microbial community (mineralization of isotopic compounds); and vi) identification of enzymatic processes related to generation of stable organic matter. The experience of the candidate and the host institution (CEBAS-CSIC) is sufficient for the development of these activities.";45000;45000;FP7-PEOPLE-2010-RG;/MC-ERG;AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS;ES;;;/SCI;1;0;0;1;0;0 98427;261732;A4A;ONG;FP7-SECURITY;SEC-2010.4.3-1;FP7;Alert for All;2011-03-16;2013-12-15;http://www.alert4all.eu;"Alert4All focuses on improving the effectiveness of one element of the People-Centred Early Warning Systems paradigm, namely alert and communication towards the population in crises management. This improvement shall be measurable in terms of cost-benefit ratio, number of affected citizens timely reached by alerts, trust of citizens on alerts and intended vs. actual impact of alert strategies. Alert4All will provide solutions to align alert procedures and processes to contemporary crises (natural or man-made), available and emerging technologies, available information sources and trends in social behaviour. To achieve this goal the Alert4All Project will: -Develop a simulation tool that models the spreading of information and human behaviour according to key influencing factors such as crisis scenario, selected communications plans, social and cultural crowds; -Investigate the role of new media in the citizens’ perception of the crisis and develop new media screening tools to allow authorities completing their picture of the situation and adapt their strategies accordingly; -Develop an information management portal through which authorities and first responders can securely share and manage the available information about the crises by means of the aforementioned tools; -Propose new operational concepts (and training material) that allow cooperation between authorities and responders, overcoming regional and national barriers thanks to the tools developed in the project; -Design a communications system architecture and protocols allowing dissemination of alert messages over diverse communications means (terrestrial, satellite, new media) to increase alert penetration, reliability and resilience in front of major disasters. -Validate the concept in critical scenarios. The Alert4All project thus provides an extensive and interdisciplinary framework, covering all key enablers to improve the effectiveness of alert and communications towards the population.";4909483,6;3497469,45;FP7-SEC-2010-1;/CP;Deutsches Zentrum fur Luftund Raumfahrte.V;DE;"TOTALFORSVARETS FORSKNINGSINSTITUT;FUNDACION TECNALIA RESEARCH & INNOVATION;INSTITUT FUR RUNDFUNKTECHNIK GMBH;BAPCO LBG;Bundesamt für Bevölkerungsschutz und Katastrophenhilfe;TECNOSYLVA SL;AVANTI COMMUNICATIONS LTD;EUTELSAT S.A.;DEUTSCHES ROTES KREUZ EV;EDISOFT-EMPRESA DE SERVICOS E DESENVOLVIMENTO DE SOFTWARE SA;UNIVERSITAET STUTTGART";"SE;ES;DE;UK;FR;PT";"/INF;/TEL;/SEC";1;0;0;1;0;0 98178;276810;ARCHOSL;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-RG;FP7;Archives of Early Human Occupation in Western Europe: OSL Chronologies beyond the Middle Pleistocene in the Iberian Peninsula;2011-03-01;2014-02-28;;'A number of important archaeological sites within the Iberian Peninsula hold the key to answering fundamental questions about human evolution and migration out of Africa into Europe. However, the existence of chronologies that are either too ambiguous, imprecise, poorly described, or only based on non-numeric dating methods, prevents the development of well sustained hypotheses on the age of such early expansions, on hominin migratory patterns, and on the driving mechanism behind such migrations. This interdisciplinary project entails the application of newly developed techniques and protocols in the field of optically stimulated luminescence (OSL) dating to obtain robust absolute chronologies on key Lower Palaeolithic archaeological sites in Western Europe. The main aim of the research is to improve and expand on the current chronological framework of important late Early Pleistocene (1.2 Ma - 780 ka) and Middle Pleistocene (780 ka - 125 ka) archaeological records in the Iberian Peninsula in order to accurately reconstruct and interpret the earliest human expansions into Europe. An integral aspect of this research is the pursuit of methodological advancements and refinements of the latest protocols in OSL dating to push back the existing age range of the technique. This project will focus on several important early human occupation sites in the Iberian Peninsula, namely the Atapuerca karstic complex in northern Spain, Orce sites (Fuente Nueva III and Barranco León), Guadix-Baza Basin, southeast Spain, and La Boella, south Barcelona, northeast Spain. This work will help to confidently reconstruct the emergence and expansion of human species in Western Europe, and improve interpretations of when and how past environmental changes have impacted human populations and their evolution.';75000;75000;FP7-PEOPLE-2010-RG;/MC-IRG;CONSORCIO PARA LA CONSTRUCCION, EQUIPAMIENTO Y EXPLOTACION DEL CENTRO NACIONAL DE INVESTIGACION SOBRE LA EVOLUCION HUMANA;ES;;;/SCI;1;0;0;1;0;0 92238;238514;MITT;ONG;FP7-PEOPLE;FP7-PEOPLE-ITN-2008;FP7;Mobility of Ideas and Transmission of Texts Vernacular Literature and Learning in the Rhineland and the Low Countries (ca. 1300-1550);2009-09-01;2013-08-31;;Mobility of Ideas and Transmission of Texts is a joint PhD programme (2009-2013) that studies the medieval transmission of learning from the ecclesiastical and academic elites of the professional intellectuals to the wider readership that could be reached through the vernacular. The programme focuses on the medieval dynamics of intellectual life in the Rhineland and the Low Countries, nowadays divided over five countries (Switzerland, France, Germany, Belgium and the Netherlands) but one cultural region in the later Middle Ages. Here, the great fourteenth-century mystics Meister Eckhart, Johannes Tauler, Jan van Ruusbroec and their contemporaries produced a sophisticated vernacular literature on contemplative theology and religious practice, introducing new lay audiences to a personal relation with the Supreme Being. The project seeks to develop a new perspective on this literary culture by looking at the readership, appropriation and circulation of texts in the contemporary religious and intellectual contexts. The programme unites expertise in the fields of medieval philosophy, religious studies, manuscript studies and Dutch and German literature, to provide structural training for interdisciplinary and international research in one of the medieval aspects of European culture of lasting merit. The training programme is built on a number of current research projects in which all full partners (Antwerp, Freiburg, Lecce, Leiden and Oxford) participate simultaneously, thus offering an adequate international infrastructure for a series of coherent PhD projects on medieval literature and learning that require a broader academic framework than the national literatures and other concepts of the modern tradition of academic disciplines. The programme prepares a new generation of medievalists for international careers in academic research, education and the presentation of the medieval cultural heritage.;2372803,85;2372803,85;FP7-PEOPLE-ITN-2008;/MC-ITN;UNIVERSITEIT LEIDEN;NL;"UNIVERSITEIT ANTWERPEN;ALBERT-LUDWIGS-UNIVERSITAET FREIBURG;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;UNIVERSITA DEL SALENTO";"BE;DE;UK;IT";"/SCI;/EDU";1;0;0;1;0;0 90157;230778;TERACAN;ONG;FP7-PEOPLE;FP7-PEOPLE-IRSES-2008;FP7;Terahertz applications of carbon-based nanostructures;2009-01-01;2012-12-31;;Creating reliable portable devices working in the terahertz (THz) range of electromagnetic spectrum is one of the most formidable tasks of contemporary applied physics, with nanostructures being at the heart of the most promising proposals. This project aims at elaborating a general approach to the description of electromagnetic processes in various carbon-based nanostructures, investigating their electromagnetic properties, and developing a physical basis for utilizing these properties in novel THz nanodevices. The complementary characters of the two key factors inherent in solid-state nanostructures, the spatial confinement of charge carriers and intrinsic nanoscale inhomogeneity of electromagnetic fields, drastically modify their electronic and optical properties. Whereas the first factor lies in the focus of current research activity of the nanoscience community, the role of the second factor was underestimated before. The proposed research is focused to fill this knowledge gap for carbon-based nanostructures. As a whole, the project contributes to the novel interdisciplinary research field, the nanoelectromagnetics, which represents a synthesis of macroscopic electrodynamics of inhomogeneous media and microscopic theory of electronic properties of nanostructures. We will study carbon nanotubes (CNTs) and graphene representing latest trends in carbon-based nanotechnology. As shown in our proposal, unique physical properties of these nanostructures provide the basis for novel THz applications. To achieve the ambitious goals of this project, the consortium involves scientists from both electromagnetic and nanostructure communities. Intensive transfer of knowledge between them is essential for success of the project.;86400;86400;FP7-PEOPLE-IRSES-2008;/MC-IRSES;THE UNIVERSITY OF EXETER;UK;;;/EDU;1;0;0;1;0;0 99363;273312;Humvar;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-IIF;FP7;Human variation: causes, patterns and consequences;2011-12-01;2012-11-30;;Mutations are the source of genetic variation in natural populations, provide material for molecular evolution and, importantly, cause human genetic diseases. Yet the mechanisms of mutagenesis are, to date, not completely understood. Low mutation frequencies limit direct observations in wet-lab experiments. However, hundreds of resequenced human genomes (including cancerous samples) and hundreds of completely sequenced genomes of other species are accumulating at a growing pace. Thus, bioinformatic analyses of mutations are becoming feasible. It is known that mutation rates fluctuate greatly from locus to locus in mammalian genomes, and that the rates of some mutation types co-vary regionally. The causes of this variation and co-variation remain largely unexplored, and deciphering them computationally is expected to unravel the intricacies of mutagenesis. Compared with wet-lab experiments, computational analyses enable us to study mutations in their native genomic environment and on a whole-genome scale. Here we propose to utilize human resequencing data in conjunction with completely sequenced mammalian genomes in order to study regional (primarily intrachromosomal) variation and co-variation in rates of different mutation types. Additionally, we will perform comparisons between cancerous and non-cancerous mutations, highlighting the unique features of mutations associated with cancer. Several statistical multivariate and multi-scale techniques will be utilized. The proposed research will advance our understanding of mutagenesis, including the unique aspects of mutagenesis during cancer. Additionally, it will provide information vital for improving models of the evolutionary process, alignment algorithms, and algorithms for the prediction of functional elements. The tools developed here are expected to bridge interdisciplinary differences in concepts and data between biology and statistics, as well as between bioinformatics and experimental biochemistry.;126387,5;126387,5;FP7-PEOPLE-2010-IIF;/MC-IIF;UNIVERSITE LYON 1 CLAUDE BERNARD;FR;;;"/SOC;/COO";1;0;0;1;0;0 94757;252935;ASSAY FOR BIOMARKERS;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IEF;FP7;Magnetic Nanoparticles for Multiplexed Assays for Low and High Molecular Weight Biomarkers;2010-06-01;2012-03-31;;The application for the FP7-PEOPLE-2009-IEF is to support a move of a postdoctoral researcher to University College Dublin, UCD. The researcher to date has published in 16 peer reviewed journals and has a current h-index of 8. With the expert training and opportunities in place at UCD, the award of the fellowship will build upon the successful start of his academic career and deliver him to a full time academic position. This research proposal outlines a new technique capable of screening biomarkers with the capability of working directly in biological samples. The benefits of monitoring biomarkers lie in their ability to reveal signs of disease before the onset of major symptoms. The proposed technique will involve synthesizing nanoparticles to contain paramagnetic and optical properties, that will then be functionalized with aptamers/ or antibodies. These functionalized particles will capture the biomarkers directly from solution, and in conjunction with non-linear magnetophoretic separation, NLM, will allow the quick separation and detection by exploiting the particles superparamagnetic and optical properties, creating a new diagnostic technology. The experimental details will deliver a single process capable of capturing the analyte as well as performing the initial sample purification and pre-concentration stage that screens multiple biomarkers for several diseases across a wide range of molecular weights and functionalities. It will deliver benefits of being both a multiplexed technique that also offers a highly desirable tagless detection mechanism. The training that accompanies this will ensure the fellow has a broad scientific understanding, crossing several scientific fields delivering an interdisciplinary research approach. When combined with the support infrastructure in place at UCD, will deliver outstanding career enhancement prospects to the applicant, delivering a new diagnostic technique to enhance the European research portfolio.;177374,2;177374,2;FP7-PEOPLE-2009-IEF;/MC-IEF;UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN;IE;;;"/SCI;/EDU;/ITT";1;0;0;1;0;0 96566;253635;NEUGLIANET;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IOF;FP7;ROLE OF ASTROCYTES IN NEURONAL NETWORK FUNCTION IN VISUAL CORTEX;2010-08-01;2014-01-31;;The biology of astrocyte–neuron interaction has emerged as a rapidly expanding field and has become one of the most exciting topics in current neuroscience that is changing our understanding of the physiology of the nervous system. In the last few years, evidence obtained by many laboratories has established the existence of neuron-astrocyte communication in culture preparations and brain slices. However, the properties of astrocytes and their physiological role in vivo is largely unknown Numerous in vitro studies have focused on investigating the basic molecular mechanisms as well as the subcellular and cellular processes involved in astrocyte-neuron communication. Yet, to begin to understand the actual active role of astrocytes in the brain function, we need to analyze this communication and its effects at a higher level of complexity, such as during neural network function and information processing in vivo. The main objective of present project is to elucidate the impact of astrocytes in neural network function and sensory information processing in vivo. The achievement of the proposed objectives will increase our current knowledge of the role of astrocytes at a higher level of complexity, filling the gap currently existing on this area of neuroscience, and therefore, will significant extend our knowledge of the physiology and function of the nervous system. Using a conceptual interdisciplinary approach that will cover different levels of analysis (from molecules to cells and networks) to gain a comprehensive vision of the nervous system function, I propose to combine multidisciplinary techniques that include electrophysiology, Ca2\ imaging, two-photon microscopy in vitro and in vivo and genetic manipulation of animal models, to characterize the functional consequences of astrocyte activity in the sensory information processing by neural networks of the visual cortex.;234337,9;234337,9;FP7-PEOPLE-2009-IOF;/MC-IOF;AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS;ES;;;"/LIF;/EDU";1;0;0;1;0;0 93530;229239;RECATABI;ONG;FP7-NMP;NMP-2008-2.3-1;FP7;Regeneration of Cardiac Tissue Assisted by Bioactive Implants;2010-01-01;2012-12-31;http://www.recatabi.com/;Heart failure is the end-stage of many cardiovascular diseases, but the leading cause is the presence of a large scar due acute to myocardial infarction. Current therapeutic treatments under development consist in cellular cardiomyoplasty where myocardial cells or stem cells are implanted alone or encapsulated in natural scaffolds (collagens) and grafted onto infarcted ventricles with the hope that cells will contribute to the generation of new myocardial tissue. This approach seems to have a beneficial effect although it is not completely understood and optimized, yet. Thus, the urgent need of better therapeutic platforms is imminent. In view of this, we created a small interdisciplinary consortium (RECATABI) with experts in areas such as material sciences, tissue engineering, stem cell technologies and clinical cardiovascular research. RECATABI will integrate and synergise their capacities in order to obtain a novel clinical platform to regenerate necrotic ischemic tissues after cardiac infarct with a simple one-time patch technology application. The consortium will accomplish this by fabricating nanoscale engineered biomaterials and scaffolds that will match the exact biomechanical and biophysical requirements of the implanted tissue. In addition, the construct may induce rapid vascularization to ensure tissue remodelling and regeneration into a newly functional myocardium. The regenerative capacity of the implants loaded with pre-adapted cells (biomechanically and biophysically trained) will be assessed in small (rodents) and large (sheep) animal models.;2929560,87;2328302;FP7-NMP-2008-SMALL-2;/CP-FP;INSTITUT QUIMIC DE SARRIA;ES;"FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.;INSTITUT DE INVESTIGACIO EN CIENCIES DE LA SALUT GERMANS TRIAS I PUJOL;ASSOCIATION CARDIO-MONDE;FUNDACIO PRIVADA INSTITUT DE RECERCA DE L'HOSPITAL DE LA SANTA CREU I SANT PAU;UNIVERSITAT POLITECNICA DE VALENCIA;CREASPINE SAS";"DE;ES;FR";"/MED;/NNT";1;0;0;1;0;0 89925;217856;TELLIBOX;ONG;FP7-TRANSPORT;SST-2007-2.1-01;FP7;Intelligent MegaSwapBoxes for Advanced Intermodal Freight Transport;2008-04-01;2011-03-31;;Faced with a trend towards increasing freight transport, a global market that is constantly growing and the need for a resource-saving transport system, it is mandatory that European transport policy shifts the balance between all transport systems.`Intelligent MegaSwapBoxes for Advanced Intermodal Freight Transport’ (TelliBox) as an all-purpose loading unit will actively promote the EU’s objectives of achieving intermodal integration and operational optimisation. By drawing together the ideas and contributions of freight forwarders, manufacturers and scientists, the scientific aim is to achieve an all-purpose, intermodal loading unit that is applicable to transport via road, rail, short sea and inland shipping. The advantages of containers and semitrailers will be combined by a MegaSwapBox. Challenges facing the development are that the MegaSwapBox has to - be trimodal, - be stackable and applicable for handling from the top, - use existing low floor wagons for rail transport, - provide an adaptable chassis for road transport, - have an optimised cargo volume of 100m? with an internal height of 3m, - have loading facilities from three sides (completely openable doors), - offer improved safety features against pilferage. Within six decisive project steps, an interdisciplinary European consortium will realise three optimised and certified prototypes which will be tested on an intermodal European corridor (PL-D-NL-UK). TelliBox will achieve its objectives by combining new materials with innovative and intelligent constructions. A complementary bundle of scientific evaluation methods and profitability calculations will reduce project risk, and the integration of all interest groups will ensure that the MegaSwapBox is accepted. The project TelliBox seeks to successfully introduce the MegaSwapBox onto the market with a view to encouraging the standardisation of new loading units in the long run.;4366534;3099665;FP7-SST-2007-RTD-1;/CP-FP;RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN;DE;"Ewals Cargo Care B.V.;HRD Trailer-Engineering GmbH;WINCANTON GMBH;Wecon GmbH Nutzfahrzeuge-Container-Technik;CTL Logistics S.A.;Wesob Spolka z Ograniczona Odpowiedzialnoscia;ZILINSKA UNIVERZITA V ZILINE;EUROPEAN INTERMODAL ASSOCIATION;Intermodal Concepts & Management AG";"NL;DE;PL;SK;BE;CH";/TRA;1;0;0;1;0;0 103838;320130;ESOF2012;ONG;FP7-SIS;SiS;FP7;Euroscience Open Forum 2012;2012-02-02;2012-12-01;;"ESOF is an interdisciplinary, pan-European meeting, held under the auspices of Euroscience, which aims to: Showcase the latest advances in science and technology Promote a dialogue on the role of science and technology in society and public policy Stimulate and provoke public interest, excitement and debate about science and technology We will achieve this by bringing together 5,000 scientists, business leaders, government officials and international media to discuss the best European science and address all of the major global issues, including energy, climate change, food and health.";1099200;599000;FP7-Adhoc-2007-13;/CSA-SA;FORFAS;IE;;;"/SCI;/SOC";1;0;0;1;0;0 99410;275542;MUSTERMAN;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-IEF;FP7;"""Music, Terror and Manipulation under the Greek Junta""";2011-06-15;2014-06-20;;"'MUSTERMAN critically studies music’s role in manipulation and terror under the Greek military Junta (1967–1974). The cultural politics and musical culture of the Junta belong to a larger history of social control under repressive Cold War regimes. So far, musicological attention on the Greek case has focused exclusively on the music of resistance to the dictatorship; the music of the regime itself remains unstudied. MUSTERMAN aims to close this gap by investigating three aspects of the Junta’s musical culture: music as a medium of manipulation and propaganda; the gender aspects of the masculinized Greek national identity propagated by the regime; and the use of music as a weapon of torture. The analysis of these aspects will combine historical and empirical research with an appropriate critical and theoretical framework. It will reconstruct and document the Junta’s musical culture through archival and textual research, and interviews with torture survivors and torturers. An interdisciplinary framework for interpreting and assessing empirical findings will be developed from concepts and tools of critical musicology, psychoanalytical theory and trauma studies, and Critical Theory. MUSTERMAN aims to deliver a monograph to a major international academic publisher. This monograph will synthesize the research into an empirically rich and theoretically grounded critical account of the abuse of music under the Junta, moving beyond traditional musicology’s tendency to treat music as an invariably emancipatory and enlightening art-form. Intermediate project aims include the development of an online database archiving the reconstructed musical culture of the Junta and two articles for peer-reviewed journals. Plans for networking and knowledge transfer include research presentations, a conference, and a proposal for a training network. Results will also contribute to current international debates on human rights, international law and the ban on torture supported by the EU.'";156042,4;156042,4;FP7-PEOPLE-2010-IEF;/MC-IEF;GEORG-AUGUST-UNIVERSITAT GOTTINGENSTIFTUNG OFFENTLICHEN RECHTS;DE;;;"/EMP;/EDU;/NET";1;0;0;1;0;0 96750;261412;CONTRACT;ONG;FP7-HEALTH;HEALTH.2010.4.2-6;FP7;Consent in a Trial and Care environment;2010-10-01;2012-09-30;;"CONTRACT is about consent. The project focuses on analysing how the legal (and underlying ethical) concepts of informed consent in the European Data Protection Directive and in the Clinical Trials Directive have had and continue to have an impact on the success of translational research. The project predominantly deals with vulnerable patients as their consent is of utmost complexity. The concept of informed consent in the two mentioned Directives will be analysed from a legal, ethical, IT-related and clinical point of view. The European approach on the matter will be compared with national concepts of informed consent for care purposes in the Member States. CONTRACT will support the European Commission and other policymakers in achieving a clear Community framework by providing clarity on different concepts of informed consent on European and national level. CONTRACT’s approach will be based on facts and figures by delivering an empirical survey about the handling of consent in European and national translational trials. CONTRACT will identify good practices in obtaining and administering informed consent in translational research and will give recommendations on possible harmonization of and common approaches to the legal framework. CONTRACT has already built a target community for its services, the “partner projects”, which will be significantly enlarged after the project’s start. CONTRACT will offer a help desk for its target audience on consent issues and will constantly support partner projects and other relevant stakeholders in balancing patient’s and research interests by a proper management of consent. In achieving these objectives the project has put together an internationally recognised interdisciplinary team of individuals and organisations with significant expertise and know-how on all areas of relevance to the project, it has drawn-up a ambitious – yet achievable - workplan, and has made every effort to identify and minimize potential risks.";581792,4;499235;FP7-HEALTH-2010-single-stage;/CSA-SA;GOTTFRIED WILHELM LEIBNIZ UNIVERSITAET HANNOVER;DE;"KATHOLIEKE UNIVERSITEIT LEUVEN;TECHNOLOGICAL EDUCATIONAL INSTITUTE OF CRETE;Custodix NV;UNIVERSITAT DES SAARLANDES";"BE;EL;DE";"/LIF;/MED;/MBI";1;0;0;1;0;0 99723;273677;Overnight Volatility;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-IOF;FP7;Overnight Volatility in Financial Markets: Causes and Consequences;2011-07-22;2013-11-11;;"This project consists of four parts, each of which will analyze a different aspect of interbank overnight rate volatility (hereafter “OV”). In the first part of the project, the implications of OV on longer term interest rates will be investigated. The expectations hypothesis notes that longer-term rates should equal expected future short-term rates plus a term premium. We will look for evidence that OV can affect the term premium embedded in longer-term rates. The analysis will be conducted for the US, Euro Area, and the UK. Cross-country comparisons are essential to identify the impact of OV under different monetary policy frameworks. We expect to find that lower OV in the interbank market leads to a lower term premium by reducing uncertainty, and thus lower longer-term rates for a given setting of the overnight rate. In the second part of the project, we will focus on the sensitivity of OV to different reserve management regimes by utilizing a dynamic optimization model of daily reserve management. Using this model, we will investigate the implications of alternative reserve management strategies on OV including the reserve management practices at the Fed and the ECB. This way, we will check whether a particular reserve management strategy is preferable in terms of achieving lower OV. The third part of the project will utilize an interdisciplinary causal search algorithm to investigate the links between OV and broader macroeconomic variables such as the GDP, the price level, and the yield curve in a structural vector auturegression framework. The last part of the project will develop an intertemporal optimization model to estimate the demand for term deposit facilities and their implications on OV. Term deposit facilities are established by the central banks (Fed, ECB, RBA) during the recent financial crisis. Because of the current nature of these developments, there has not been any work done understanding the functioning of these deposit facilities.";179477,8;179477,8;FP7-PEOPLE-2010-IOF;/MC-IOF;KOC UNIVERSITY;TR;;;"/EMP;/SOC;/COO";1;0;0;1;0;0 94750;256475;GETWA;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-RG;FP7;Gender Equality Through Women's Agency in state socialist Poland and Georgia;2010-08-01;2014-04-03;;This projects links the state socialist conceptualizations of gender equality with current struggles for women’s rights at national, regional and supranational level proposes new conceptualization of women’s agency under the authoritarian regimes and with limited access to international networking. It employs concepts of “gender equality”, “ women’s agency”, “state feminism” and “transnational women’s movement” as the major categories for studying the development of state equality projects and the impact of state socialism on the gender regimes in Georgia between 1921-1990 and in Poland between 1945-1989. This cross-national study of the state-socialist project of gender equality will apply interdisciplinary research methods including oral history, institutional ethnography, textual analysis and archival work to: 1.) destabilize existing paradigm of understanding the relationship between state socialism and post-state socialist gender relationships in terms of disruption and discontinuity, 2.) reconceptualize the notion of women’s agency under state socialism by recognizing socialist states as site for development of supranational women’s agenda, before Beijing Conference in 1995, 3.) deliver more comprehensive understanding of state socialist “gender equality” by recognizing the role that local political and cultural forces, religion and nationalism played in shaping and altering state socialist project of gender equality in various locations.;75000;75000;FP7-PEOPLE-2009-RG;/MC-IRG;UNIWERSYTET WARSZAWSKI;PL;;;/SCI;1;0;0;1;0;0 95323;252379;THE COSMIC SOUL;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IEF;FP7;The Cosmic Soul: Renaissance Humanism and Natural Philosophy;2010-09-01;2012-08-31;;I am proposing to spend two years at the Center for the History of Philosophy and Science (CHPS) at the Faculty of Philosophy of Radboud University Nijmegen (the Netherlands). There, I propose to carry out a large research project and at the same time to acquire a number of new skills in the domains of teaching, editorship, organization and research methodology. I have good reasons for believing that my planned publications, together with my expanded curriculum, will allow me to compete successfully for a university position in Europe at the end of my fellowship. My research project, which will culminate in my third book-length monograph, aims to investigate the impact of Renaissance humanism on the development of natural philosophy (a traditional discipline that included physics, biology, astronomy, etc.) in the sixteenth and seventeenth centuries. In particular, I shall investigate Renaissance and early modern ideas concerning the provenance of life and their link to notions of universal animation, of the ‘world soul’, and of celestial as well as divine causation. Although the history of this ‘cosmic dimension of the soul’ is not only a fascinating subject, but also very central to our understanding of early modern thought, it has been strangely neglected in the available scholarship. My proposed research topic requires an interdisciplinary approach, as it involves the histories of philosophy, of science, of theology and of medicine. The CHPS at Nijmegen is, in Europe, probably the best place for such a project, because of the presence of eminent historians of both philosophy and science in its staff. My proposed sojourn at the CHPS will combine the research just sketched with the acquisition of skills that are strictly related to my research.;208399,2;208399,2;FP7-PEOPLE-2009-IEF;/MC-IEF;STICHTING KATHOLIEKE UNIVERSITEIT;NL;;;"/SCI;/EDU;/ITT";1;0;0;1;0;0 96412;253662;EU SEXUAL DIVERSITY;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IEF;FP7;A Comparative Study of LGBTQ Rights and Art in the UK and Poland within the Context of the EU Idea of Sexual Diversity;2011-01-10;2013-01-09;;My research focuses on the condition of LGBT rights and art in the UK and Poland within the context of the EU idea of sexual diversity. The state of LGBT rights as civil rights in the EU differs significantly between member countries. My intention is to research comparatively Poland and the United Kingdom. The Anglo-Polish perspective on sexual politics of human rights would let me analyze the status of LGBT rights, activism and art from the opposite poles within the European Union struggling for the democracy of sexual diversity. From the Polish perspective, with the implementation of the Same-Sex Civil Partnerships in Britain in 2005 , the success of LGBT rights has been almost reached. The Polish perspective (like other Eastern European new member states: Lithuania, Latvia, Slovakia, Bulgaria) is totally different where persistent homophobia defines state policy . The difference creates different contexts and conditions for human rights activists and contemporary artists dealing with LGBT subjects and expressing artistically their queer identities. My aim is to examine histories, policies and aesthetics of queer rights and arts in the UK and Poland. Thus in my research I combine social and humanist/artistic perspective on the subject. The fellowship would advance my teaching, curating and research into LGBT rights and art in the EU. My intention is to contribute comparative research on LGBT agency to the interdisciplinary Centre for the Study of Sexual Dissidence which specializes in advance research into LGBT issues. Because power in Poland and Eastern Europe still denies agency to LGBT members of the society (and there are also cases of censorship of contemporary queer art), one witnesses a radicalisation of the concept of sexual dissidence here. My research into the sexual dissidence in Britain and Poland can therefore enrich the activities of the Centre for the Study of Sexual Dissidence.;224727,2;224727,2;FP7-PEOPLE-2009-IEF;/MC-IEF;THE UNIVERSITY OF SUSSEX;UK;;;"/SCI;/EDU;/ITT";1;0;0;1;0;0 98991;268154;SOBONA;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-IRSES;FP7;Solar Cells Based on Nanowire Arrays;2011-06-01;2014-09-30;;"The area of photovoltaic devices is a very promising field for technological developments, with a very strong ecological and economic impact. The purpose of this exchange program is to create novel photovoltaic devices with record efficiencies using interdisciplinary expertise of the partners, and thereby to propose new concepts for solar cells. Joint experiments and training of researchers and PhD students will be carried out during the program. We plan to design and produce state-of-the-art prototypes of hybrid solar cells, which could include the best features from both thin-film and nanowire technologies. In particular, new promising routes for controlled engineering of CdTe/CdS junction interface in thin-film solar cells will be explored by growing CdTe nanowires at high temperature and under controlled ambient conditions. Other material interchanges will be performed using as platform recent advances in the growth of a wide range of III-V and II-VI nanowire arrays. To achieve the research goals of the project it is planned to carry out intensive exchange of research staff and PhD students. Five high rank international research groups will participate in the program, three of which are represented by the EU universities: • University of Durham, Department of Physics, Durham – UK (UDUR) • University Jaume I, Departament de Física, Castelló de la Plana - Spain (UJ-I) • University of Würzburg, Experimental Physics VI, Germany (UW) And the two third country groups are represented by the following Russian institutions: • Ioffe Physical-Technical Institute of the Russian Academy of Sciences (Ioffe PTI) • St. Petersburg Academic University of the Russian Academy of Sciences (SPb-AU) This project will allow the essential knowledge and material transfer between the partners, strengthening the collaborations and helping to establish a long-term research co-operation.";302100;302100;FP7-PEOPLE-2010-IRSES;/MC-IRSES;THE UNIVERSITY OF LIVERPOOL;UK;"UNIVERSITAT JAUME I DE CASTELLON;JULIUS-MAXIMILIANS-UNIVERSITAT WURZBURG";"ES;DE";"/EMP;/SOC";1;0;0;1;0;0 93643;241778;NEUROBID;ONG;FP7-HEALTH;HEALTH-2009-2.2.1-4;FP7;Neuroscience on Barriers in Development;2010-01-01;2013-12-31;http://www.neurobid.eu;"Brain diseases are one of the most prevalent groups of diseases in Europe with estimated annual costs amounting to €386 billion (1). Data collected by the WHO suggest that brain diseases are responsible for 35% of Europe’s total disease burden (1). In the treatment of neurological disease, the blood brain barrier (BBB) still represents an obstacle for the delivery of drugs to the brain and thus a major challenge for the development of therapeutic regimens. Understanding the molecular basis and functioning of the BBB in health and disease, including transport mechanisms across the BBB, therefore holds significant potential for future strategies to prevent and ameliorate neurological disease. Recent research indicates that some neurological disorders have a developmental etiologic component. The major goal of the NEUROBID project is thus to understand the molecular mechanisms and function of the BBB in health and disease both in the developing brain and the adult central nervous system. With an interdisciplinary consortium from the fields of developmental neurobiology and BBB research, NEUROBID aims to (i) understand the involvement of normal and disturbed BBB function in normal and abnormal brain development and (ii) to develop novel strategies for drug delivery to the brain. Unique transport mechanisms across the BBB will be used to target potential therapeutic macromolecular and cellular agents specifically to the brain barriers and transport them into the brain. The main target disorders of NEUROBID are non-inherited neurodevelopmental disorders arising from perinatal adverse exposure, such as cerebral palsy, and classic adult neurological disorders such as multiple sclerosis and stroke. In the long term, NEUROBID hopes to pave the way for new treatment strategies and thus reduce the economic and social burden of neurological disease. 1. Olesen J, et al. Consensus document on European brain research. J Neurol Neurosurg Psychiatry 2006;77 Suppl 1:i1-49.";4194375,47;2996324;FP7-HEALTH-2009-single-stage;/CP-FP;MEDIZINISCHE HOCHSCHULE HANNOVER;DE;"INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE;UNIVERSITAETSKLINIKUM WUERZBURG - KLINIKUM DER BAYERISCHEN JULIUS-MAXIMILIANS-UNIVERSITAT;CERTARA UK LIMITED;Nathalie Strazielle;UNIVERSITAIR MEDISCH CENTRUM UTRECHT;University of Melbourne;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;GOETEBORGS UNIVERSITET;Angewandte Biotechnologie GmbH";"FR;DE;UK;NL;AU;SE;AT";"/LIF;/MED";1;0;0;1;0;0 103348;298100;VALUES;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IEF;FP7;NORMATIVE PRACTICES IN THE PUBLIC SPHERE. A THEORETICAL MODELING OF FORMS OF CIVIC ENGAGEMENT;2012-07-01;2014-06-30;;'In this research project I propose an approach to normativity and to the functioning of norms in the coordination of social life that is based upon a theory of normativity as practice. The aim of this project is threefold. Firstly, to show that our understanding of normativity remains utterly opaque as long as we do not take into account the plurality of empirical practices through which normative regulations are effected. Secondly, to prove that sociality is one of the central sources of normativity and that the functioning of normativity cannot be fully understood unless the epistemic implications of the social dimension are considered. Thirdly, to develop a theoretical model and conceptual tools to be used in the analysis and resolution of moral disagreements and political controversies. A pragmatist epistemology of practices is the conceptual framework within which this project has been conceived, while the theory of rationality as a social institution is the conception of rationality that grounds it. Jointly, these approaches require and justify the thoroughly interdisciplinary approach to normativity that this project intends to pursue.';269096,4;269096,4;FP7-PEOPLE-2011-IEF;/MC-IEF;ECOLE DES HAUTES ETUDES EN SCIENCES SOCIALES;FR;;;/SCI;1;0;0;1;0;0 92206;238700;NANOPOLY;ONG;FP7-PEOPLE;FP7-PEOPLE-ITN-2008;FP7;Hybrid Models for Tailoring Nano-Architectures of polymers;2009-10-01;2013-09-30;;The large scale production of commodity polymers is increasingly shifting overseas. Europe still plays a major role in polymer processing and product development, but the competition with the US and Asia requires distinctive efforts to sustain this leadership. Thus, it is decisive for European researchers and companies to design innovative, specialised commodities and optimise current production strategies. NANOPOLY’s main scientific objective is to further create, exchange and spread-out such know-how systematically within a European network in order to make this progress available and exploitable for European industries and coming generations of researchers. NANOPOLY will be unique in combining the strengths of applied mathematics/software engineering on the one hand and macro-molecular chemistry/reaction engineering on the other hand. These two sets of competences are currently rather unrelated but represent an important source of innovation for creating new models and associated software tools that permit new rational designs of polymer materials. NANOPOLY’s main training objective is the education of a new generation of researchers who are able to bridge the still significant gap between the two mentioned sets of competences. The job market urgently calls for researchers with suchlike sophisticated knowledge and interdisciplinary training. These prospects will make participation in the network a rewarding career option. Through superior training, intense cooperation, and outreach the network will build-up an exeptional multi-disciplinary, European-based community that is able to achieve the crucial transfer of knowledge between the associated fields and thus permit major innovation in improving technological processes that allow tailoring nano-architectures of polymers to specific requirements.;2702706;2702706;FP7-PEOPLE-ITN-2008;/MC-ITN;FREIE UNIVERSITAET BERLIN;DE;"Dr. M. Wulkow Computing in Technology GmbH;STICHTING DUTCH POLYMER INSTITUTE;BASF SE;EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH;UNIVERSIDADE DO PORTO;USTAV MAKROMOLEKULARNI CHEMIE AV CRVVI;UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA;UNIVERSITEIT VAN AMSTERDAM";"DE;NL;CH;PT;CZ;ES";"/SCI;/EDU";1;0;0;1;0;0 102861;298337;AMORPH;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IEF;FP7;Analysis and Modelling of the Reactivity of Pozzolans during Cement Hydration;2012-06-01;2014-05-31;;"'Currently, the annual global cement production is estimated to be 3.3 billion tons1. Even though the CO2 emissions associated with the final product, concrete, are low, the massive scale of production, means that the cement industry accounts for 5-8 % of the global annual anthropogenic CO2 emissions3. One of the most effective ways to improve sustainability is the blending of Portland cement with supplementary cementitious materials (SCMs)2,3. However many local sources are fully exploited and a decline in production of blastfurnace slags and fly ash is expected due to future developments in steel and electricity production4. Therefore locally available alternatives to these traditional SCMs need to be found to achieve higher cement replacement levels and a more sustainable cement industry. Unravelling the impact of this expanding and diversified group of SCMs on the hydration reactions and performance of cement constitutes a major scientific challenge. The diversity of SCMs calls for novel generic approaches that will enable direct prediction and control of performance; compared to the current practice of case-by-case empirical testing. This project proposes a novel interdisciplinary approach, building on the geological background of the fellow combined with the materials science perspective of the host. Novel concepts of surface chemistry, recently developed in geochemistry, will be applied to the behaviour of SCMs in cement. The focus will be on investigating the effect of SCM and solution chemistry on the rate of the nanoscale surface processes of dissolution and precipitation. The impact of SCMs on the product assemblage and microstructure will be modelled and compared to experiment, exploiting recent breakthroughs in thermodynamic and microstructure modelling of cement systems. Finally, the results obtained will be transferred to practice through practical methodologies for testing SCM reactivity in a basic laboratory environment.'";192622,2;192622,2;FP7-PEOPLE-2011-IEF;/MC-IEF;ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE;CH;;;/SCI;1;0;0;1;0;0 95769;252981;HCSP IN BETA-CELLS;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IEF;FP7;The highly calcium-sensitive pool of granules in biphasic insulin secretion: Experimental and theoretical investigations;2010-06-01;2012-01-12;;"Insulin is released from the pancreatic beta-cells in a biphasic manner in response to a step in the ambient glucose concentration, and the loss of first-phase secretion is an early marker of diabetes. Studies have shown that there exist pools of insulin secretory granules with different calcium sensitivities. The project will study the nature, regulation and role of the highly calcium-sensitive pool (HCSP) in pancreatic beta-cells. Special focus will be on its relation to "newcomer granules", which fuse shortly after arriving to the membrane, during biphasic insulin secretion. We will apply a combination of well-established experimental methods such as patch-clamp techniques, life confocal and TIRF imaging, in novel combinations with knock-down of key exocytotic proteins, in particular Syntaxin and Synaptotagmin. The experimental part will be complemented and supported by modelling studies, building on our recently published model, which identified the HCSP with newcomer granules. This interdisciplinary project will test the model experimentally, and vice versa, use the model to suggest key experiments. The suggested work will complement the theoretical training of the fellow with hands-on experience.";136002,05;136002,05;FP7-PEOPLE-2009-IEF;/MC-IEF;LUNDS UNIVERSITET;SE;;;"/SCI;/EDU;/ITT";1;0;0;1;0;0 107274;331184;BENGRAS;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IIF;FP7;Bandgap engineering of graphene by molecular self-assembly;2013-06-16;2015-06-15;;'BENGRAS is a Marie Curie IIF project that focuses on multidisciplinary transfer of knowledge from a promising Australian early career researcher to KU Leuven towards the design and synthesis of novel functional nano-materials and the development of advanced analytical techniques for material analysis. The project will study bandgap engineering in graphene induced by physi- and chemi- sorption of self-assembled molecular monolayers, which is an interdisciplinary research topic centered at the interface between materials science, supramolecular chemistry, nanoscience and physics. Graphene, a material consisting of flat one-atom-thick sheets of carbon atoms has enormous potential for the use in electronic transistors because of the unique electronic properties and the reduced dimensionality. Graphene is a ‘zero-gap’ semiconductor and to unlock its electronic properties two basic requirements must be satisfied. Firstly, precise control over electronic band structure (bandgap) is needed. This can be achieved by adsorbing atoms and molecules (e.g. H, OH, K, NH3) on its surface thus generating local mid-gap states. Secondly, the means to control the degree of ordering and periodicity of modified graphene layers are to be derived. In other words, the regions where bandgap can be locally tuned have to be extended to a micron scale for practical applications. At present, this issue remains largely unexplored. This project will investigate the electronic structure of graphene the surface of which has been nano-patterned by physisorped (i.e. weak surface interactions) and covalent (i.e. strong surface interactions) molecular monolayers. Through BENGRAS the fellow will contribute extensive expertise in carbonaceous materials and spectroscopy towards controlled modification of electronic properties of graphene and, designing appropriate analytical methods for the study of low-dimensional materials using optical spectroscopy methods at the nanoscale.';177000;177000;FP7-PEOPLE-2012-IIF;/MC-IIF;KATHOLIEKE UNIVERSITEIT LEUVEN;BE;;;/SCI;1;0;0;1;0;0 86709;213803;ROC;ONG;FP7-NMP;NMP-2007-3.2-2;FP7;Radiochemistry on chip;2008-09-01;2011-08-31;http://www.roc-project.eu;"The aim of this project is the design, fabrication and implementation of a microdevice able to synthesise radiopharmaceuticals for Positron Emission Tomography (PET) analysis, a technique usually employed in medicine for its unsurpassed sensitivity and specificity. We propose to develop a modular microfluidic architecture which can be used for standard synthesis protocols as well as for R&D of new radiopharmaceuticals. In order to achieve this target, emerging technologies in the field of micro reactors and micro total analysis systems (?–TAS) have to be applied to the synthetic pathways typical for radiopharmaceuticals, thus improving the traditional approach in terms of efficiency and safety. A deep knowledge of the chemical processes and of the separation techniques involved in radiosynthesis is needed to define the features of the modules to be fabricated as well as state of art techniques in the field of micro fabrications and microfluidics for the implementation of high performance micro devices. Standard synthesis protocols and new radiopharmaceuticals will be carried into the micro devices thus evaluating their efficiency and versatility. The yields and the purity of the products produced into micro devices will be compared with those obtained with traditional methods and tested in vivo for Positron Emission Tomography (PET) analysis. To ensure the success of the overall project, we will take advantage of a strict collaboration between chemists, physics and engineers in an interdisciplinary approach. For this purpose, we built an international network collaboration between academic partners dealing with the technological side, an industrial partner for checking the system robustness and a physiological clinical institute able to evaluate the end-user outcome.";3845585,6;2699912;FP7-NMP-2007-SMALL-1;/CP-FP;CONSIGLIO NAZIONALE DELLE RICERCHE;IT;"EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH;UNIVERSITY OF HULL;LEIBNIZ-INSTITUT FUR ANALYTISCHE WISSENSCHAFTEN-ISAS-EV;UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK;SIEMENS AKTIENGESELLSCHAFT";"CH;UK;DE;IE";/IND;1;0;0;1;0;0 88819;222087;KESTCAP;ONG;FP7-INCO;INCO-2007-2.1;FP7;Korea-EU Science and Technology Cooperation Advancement Programme;2008-07-15;2012-01-14;;"KESTCAP, Korea EU Science and Technology Cooperation Advancement Programme, is based on the Science and Technology agreement signed between Korea and the EU, Nov 2006 and seeks to; provide a platform to strengthen the S&T agreement between Korea and the EU; improve this cooperation by identifying S&T fields of common interests of Korea and the EU; set up a website and information help desks to respond to specific inquiries on existing opportunities and available funding instruments; contribute to the Korea-EU policy dialogue on science, technology, and innovation. The specific objectives are to: Develop sustainable cooperation strategies; disseminate information and promote cooperation; and organise and support cooperative events between Korea and the EU. Work packages have been organized to ensure effective delivery of these objectives. They will create: a website portal to European-Korean S&T collaboration; an online database of researchers involved in interdisciplinary and collaborative EU-Korean research; information/help desk services for researchers seeking collaboration opportunities; networks of researchers involved in and interested in collaboration, and fora to share information and experiences; promotion of existing collaboration and opportunities for new collaboration; bilateral research networks to promote collaboration; and thematic networks in areas of mutual priority. KESTCAP is coordinated by KICOS located in Seoul, Korea. The implementation strategy will use 3 key instruments: study, website, and fora. Events such as fora shall be organised in a "top-down" manner and will be complemented by "bottom-up" fora. The Ministry of Education, Science and Technology, MEST, shall be funding approximately half of the total budget.";1022912;465000;FP7-INCO-2007-2;/CSA-SA;NATIONAL RESEARCH FOUNDATION OF KOREA;KR;"KIST EUROPE KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY EUROPE FORSCHUNGSGESELLSCHAFT MBH;Ministry of Education, Science and Technology";"DE;KR";"/SCI;/COO";1;0;0;1;0;0 92600;234359;EMAR2RES;ONG;FP7-TRANSPORT;SST.2008.6.0.6.;FP7;Support Action to initiate cooperation between the Communities of European MARine and MARitime REsearch and Science;2009-11-01;2012-05-31;;Nearly all significant developments in the marine/maritime area originate from Europe, a true maritime continent. Consequently, the Marine/Maritime Science and Research Communities are among the world leaders in their respective fields, disciplines and sectors. To maintain its leadership and competitiveness, Europe must take advantage of new market opportunities and address the global challenges by means of focused RDI. Unfortunately the complexity and intricacy of the marine/maritime area has lead to widespread fragmentation of research efforts and actors. It is therefore important to identify and establish appropriate mechanisms to strengthen the cross-sectoral and interdisciplinary cooperation, key ferment for innovation, between both research communities. To this effect, the ETP WATERBORNE and the informal Post Aberdeen Marine Interest Group came together as they would benefit from an appropriate and efficient cooperation framework to achieve the Lisbon agenda in a sustainable way. To tackle global issues such as Climate Change and Competitiveness, the different interests and elements affecting such matters need to be integrated in a consistent way. Building on the EU’s Maritime Policy and ERA, the key challenge for the EU Policies is to enable sustainable economic expansion, taking into account the environmental, economical and social aspects in a holistic way. This project will initiate the process for this holistic approach by identifying and generating a framework of cooperation for the two communities. It will focus on maritime transport but will form the basis for a wider reflection in the future. This framework would be build by identifying: the areas of common interest, of possible synergies and the most promising cooperation/integration structure. A Policy Interface Panel composed of representatives of the two Research Communities will be instrumental in reaching the largest possible consensus to ensure the best support and public awareness.;536045;498085;FP7-SST-2008-RTD-1;/CSA-SA;Community of European Shipyards Associations asbl;BE;"FONDATION EUROPEENNE DE LA SCIENCE;European Council for Maritime Applied R&D Association;European Marine Equipment Council/Conseil Europeen de l'equipment naval;FOUNDATION WEGEMT - A EUROPEAN ASSOCIATION OF UNIVERSITIES IN MARINE TECHNOLOGY AND RELATED SCIENCES";"FR;BE;NL";"/TRA;/SCI";1;0;0;1;0;0 96445;254783;SOMEART;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IOF;FP7;Sociological identification of the actors, practices, discourses and technologies involved in the conservation of media-art works;2010-07-01;2013-06-30;;The increasing engagement of artists with film, video, computers and the internet, has enabled the emergence of an unprecedented variety of ‘media-art’ forms, such as video-art, audio-visual installations, multimedia art, digital-art or net-art. However, the dependence of these media-art works on rapidly evolving technologies makes these works one of the most fragile parts of our contemporary artistic heritage. This research proposes a pioneering sociological investigation on media-art conservation practices. Its main objective is to identify the networks of technologies, practices, discourses and actors involved in the preservation of media-art works These objectives will be met by undertaking advanced training at New York University’s Sociology Department (USA) and by conducting an ethnographic study of media-art conservation practices at the Museum of Modern Art of New York (MoMA). This investigation will be transferred to the Centre for Research on Socio-Cultural Change (CRESC) at The Open University (UK), where it will contribute to establish a new line of research on the material dimensions of culture. The results of the study will be of great significance for both museum professionals in charge of the conservation of media-art collections and for cultural sociologists dealing with the processes of cultural preservation. This project will be instrumental to forge an international and interdisciplinary research network of academics, museum and cultural-policy professionals working on the intellectual and policy-related challenges facing contemporary art conservation and, more widely, culture in a digital age.;239551;239551;FP7-PEOPLE-2009-IOF;/MC-IOF;THE OPEN UNIVERSITY;UK;;;"/LIF;/EDU";1;0;0;1;0;0 98921;272389;CAMLC10;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-IEF;FP7;"""Fabrication of Large Loading Capacity, Stimuli-Responsive and Release-Controlled Drug Delivery Nanodevices""";2011-07-01;2013-06-30;;'The target of the present project is to fabricate large loading capacity, stimuli-responsive drug delivery nanodevices (DDNDs) with potential application in anticancer therapy. The proposed theme is central to People Programme for Career Development framed under FP7 within a research area which is truly at the cutting-edge and which is strongly interdisciplinary (materials, chemistry and nanoengineering). The proposed work falls directly under “The European Strategy for Nanotechnology and the Nanotechnology plan”. In particular, there are two themes under this Action Plan addressed by this proposal, e.g. Health and NMP (Nanosciences, nanotechnologies, materials and new production technologies). The proposal involves both materials preparation and drug loading/releasing processes. The DDNDs will be made in three steps. Firstly, magnetic Fe3O4 nanoparticles (NPs) are prepared. Then a decomposable FeOOH shell will be coated on the NPs. Finally, the above core-shell structures will again be coated by a layer of mesoporous silica forming core-double shell structure. The DDNDs with increased hollow volume will be obtained by the decomposition of the FeOOH inner shell. Thereafter, the drug loading and releasing will be done in two separated steps where the release can be triggered by a stimulus input, e.g. sharp pH change. All structures/devices obtained from these steps will be thoroughly characterised. The evaluation on the delivery efficiency and improvement on the fabrication process parameters will be made according to the characterisation results. In particular, the ‘zero-release’ before the stimuli input, the load maximization per DDND and the sustainability of the release once triggered will be the main aims to be achieved in the project. As fulfilled, all pre-set training objectives will be realised by the knowledge and competencies gained in the project and will definitely benefit to the candidate career development and mobility among the European Research Area.';209092,8;209092,8;FP7-PEOPLE-2010-IEF;/MC-IEF;THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;UK;;;"/EMP;/EDU;/NET";1;0;0;1;0;0 98497;273643;METOIL;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-IEF;FP7;METABOLOMICS OF TIDAL ORGANISMS TO INDICATE OIL POLLUTION;2011-06-01;2014-05-31;;'Metabolomics is a new research field that evaluates the changes in the metabolite profiles within organisms as a result of normal physiological processes, from onset of disease, or from exposure to environmental toxins or other stressors. The goal of the METOIL is to understand the metabolomic state of a subject by extracting, identifying and quantifying all the small molecule compounds (metabolites) to assess the toxicological risk and consequences of environmental pollution by polycyclic aromatic compounds (PACs) and other oil hydrocarbons. Metabolomic profiles of different marine organisms (seaweeds, polychaetes and mussels) will be studied to determine whether they can be used as pollution indicators and sentinel biosensors. The analytical methods implemented to characterise the metabolomes of the study organisms will be cutting-edge, powerful, reliable, and so far they are only possible in very few European laboratories. Advanced chemometric methods will be applied to develop a systematic methodology to ascertain how the metabolomes of the study species are affected and the metabolites that mostly determine that trends. METOIL is highly interdisciplinary as it involves analytical chemists, biologist, environmental metabolomics, ecotoxicological risk and chemometricians. METOIL implies cutting-edge, novel research with the ambition of building and applying a new approach for risk assessment related to contamination by spilled hydrocarbons. It is worth noting that METOIL can be applied to monitor the environmental situation of the Galician coast (NW Spain) and other affected areas strongly affected by chronic hydrocarbon spillages caused by the intense traffic of oil tankers navigating through the International Corridor for the Navigation of Special Goods. METOIL will, thus, be relevant to protect intertidal areas which are relevant for seafood and seaweed growing and collection which are intended for human consumption.';230627,2;230627,2;FP7-PEOPLE-2010-IEF;/MC-IEF;KOBENHAVNS UNIVERSITET;DK;;;"/EMP;/EDU;/NET";1;0;0;1;0;0 86652;203459;WOOD-NET;ONG;FP7-REGPOT;REGPOT-2007-1-01;FP7;The implementation of research potential of the Latvian State Institute of Wood Chemistry in the European Research Area;2008-06-01;2011-05-31;;"The project’s objective is to improve the research capacities and to reinforce the S&T potential of the Latvian State Institute of Wood Chemistry (LSIWC) in its scientific excellence with the aim of unlocking its capacity and make it accessible for ERA; to strengthen LSIWC as a central part, which ensures the smooth integration of researchers from convergence and outermost regions in a field vital for the social-economic development of Europe and Latvia such as Forestry and Forest Products. The project embraces thematic priorities such as the investigation of the structure and biodegradation of wood as a construction material and a cultural historical object to ensure its durability and competitiveness in the changing climate and biodiversity conditions; interdisciplinary theoretical wood studies on the molecular and nano-level, and development of technologies for chemical compounds, production of composite materials and energy from wood, its components and other types of biomass; rational utilization of woodworking and wood processing residues for the development of innovative multifunctional products for agriculture, forestry and environment protection. The project will promote the exchange of know-how and experience, formation of strategic co-operation partnership between the related leading European research centres. It will activate the dissemination of scientific information and joint results, will expand the involvement of young researchers in the scientific environment. The project envisages the acquisition of unique research equipment and upgrading of the existing one, which will extend the research potentialities, strengthen the Institute as an international research centre and make it attractive for the co-operation partners. 51 institutions as provisional cooperation partners from 24 countries will predicted: 41 from 20 ERA countries (between them 14 from 9 new EU countries); 10 from 4 ICPC (Eastern European and Mediterranean) countries.";1176200;1049320;FP7-REGPOT-2007-1;/CSA-SA;LATVIJAS VALSTS KOKSNES KIMIJAS INSTITUTS;LV;;;/POL;1;0;0;1;0;0 88875;212304;TESS;ONG;FP7-ENVIRONMENT;ENV.2007.4.2.1.1.;FP7;Transactional Environmental Support System;2008-10-01;2011-06-30;;TESS will assist policy makers to integrate knowledge from the EU, national, regional and local level into the decision making process while also encouraging local people to maintain and restore biodiversity ecosystem services. To achieve this, a transactional environmental decision support system will be designed, linking central policy planning to local livelihoods. To develop this system, TESS will first research the needs and capacities of central policy makers and local actors, identify paths and trajectories of cooperation, and model required transactions between the central and the local in relation to each one’s needs. A set of representative case studies from the whole EU (including the New Member States and pre-accession countries) will test the validity of the models and consolidate the project’s results into the design for a transactional environmental decision support system, named TESS. TESS will also include base-line information and predictive models for Strategic Environmental Assessment (SEA), Sustainability (Impact) Assessment (SIA) and Environmental Impact Assessment (EIA). TESS will be supplemented by a set of brief and memorable policy guidelines to ensure its usefulness and enable its application in a European context. The process of developing TESS will be facilitated by a large interdisciplinary consortium, in which participants include European associations with a strong network of support and influence not only in the Brussels milieu, but also at the grassroots.;2343455,24;1801111,47;FP7-ENV-2007-1;/CP-FP;ARISTOTELIO PANEPISTIMIO THESSALONIKIS;EL;"DOGAL HAYATI KORUMA VAKFI;CENTER ZA KARTOGRAFIJO FAVNE IN FLORE ZAVOD;INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE DELTA DUNARII;TERO MONOPROSOPI IKE;SZENT ISTVAN UNIVERSITY;ZENON FELIKS TEDERKO;ANATRACK LTD;Federation des Asssociations de Chasse et Conservation de la Faune Sauvage de l'Union Europeenne;BOURNEMOUTH UNIVERSITY;ERENA,ORDENAMENTO E GESTAO DE RECURSOS NATURAIS LIMITADA;EUROPEAN SUSTAINABLE USE SPECIALISTGROUP OF IUCN/SS;TALLINNA TEHNIKAULIKOOL;NATURAL ENVIRONMENT RESEARCH COUNCIL";"TR;SI;RO;EL;HU;PL;UK;BE;PT;EE";"/ECO;/ENV;/POL";1;0;0;1;0;0 93346;243860;NILTHERA;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-RG;FP7;Novel Interleukins for immunotherapy of Asthma;2010-01-01;2012-12-31;;Allergies are increasing in incidence at an alarming rate. One in three Europeans suffers from an allergy and one in ten children suffers from asthma. From the E.U. perspective, the cost from allergies in terms of health care and absenteeism from work is estimated at 45 billion euros a year. Despite prioritization of allergies and asthma in recent E.U. Framework Programme activities, there are major gaps of knowledge in this area that hamper the design of new therapeutic strategies. Recently, a new family of cytokines termed lambda IFNs, Type III IFNs or IL-28/29 (IFN?/IL-28s) was described. IFN?/IL-28s signal though a unique receptor complex (IL-28R?/IL 10R2) and possess antiviral and antitumour activity. However, their role in adaptive immunity and allergic diseases has not been explored. This is despite two reports linking the levels of expression of IFN?/IL-28s with reduced severity of asthma in humans. The host laboratory has therefore initiated a study to investigate the role of IFN?/IL-28s in allergic asthma and found that IFN?/IL-28s possess potent immunomodulatory activity that suppresses allergic airway disease in mice. The primary objective of this proposal is to further explore this observation through (i) the in-depth investigation of the role of IFN?/IL-28s in allergic airway disease, (ii) the unwinding of the cellular and molecular events involved, (iii) and the development of novel immunotherapeutic approaches for the treatment of allergic asthma. The secondary objective is to support reintegration and career development of the Marie Curie fellow by expanding her training to chronic inflammatory disease pathogenesis and to new technologies and interdisciplinary skills. The high quality research environment of the Host Organization, the international collaborations of the host laboratory which is a partner and coordinator of other FP7 Actions and the innovative and translational nature of the project guarantee the success of both aims of the proposal.;45000;45000;FP7-PEOPLE-2009-RG;/MC-ERG;IDRYMA IATROVIOLOGIKON EREUNON AKADEMIAS ATHINON;EL;;;/SCI;1;0;0;1;0;0 94137;244592;GINI;ONG;FP7-SSH;SSH-2009-2.2.1.;FP7;Growing Inequalities' Impacts;2010-02-01;2013-07-31;http://www.gini-research.org/articles/home;The project focus are inequalities in income/wealth and education and their social/political/cultural impacts. It combines an interdisciplinary approach, improved methodologies, wide country coverage, a clear policy dimension and broad dissemination. It exploits differences between and within countries in inequality levels and trends to understand impacts and tease out implications for policy and institutions. It highlights potential effects of individual distributional positions and increasing inequality for a host of ‘bad outcomes’ (societal and individual) and allows feedback from impacts to inequality in a frame of policy-oriented debate and comparison across 25 EU countries, USA, Japan, Canada and Australia. Social impacts include educational access and achievement, individual employment opportunities and labour market behaviour, household joblessness, living standards and deprivation, family and household formation/breakdown, housing and intergenerational social mobility, individual health and life expectancy, and social cohesion versus polarisation. Underlying long-term trends, the economic cycle and the current financial and economic crisis will be incorporated. Politico-cultural impacts investigated are: Do increasing income/educational inequalities widen cultural and political ‘distances’, alienating people from politics, globalisation and European integration? Do they affect individuals’ participation and general social trust? Is acceptance of inequality and policies of redistribution affected by inequality itself? What effects have political systems (coalitions/winner-takes-all)? Finally, it focuses on costs and benefits of limiting income inequality and its efficiency for mitigating other inequalities (health, housing, education and opportunity). A detailed flexible plan and support from an outstanding Advisory Board will allow the highly experienced research team to deliver important new answers to questions of great import to European societies.;3521250;2699795;FP7-SSH-2009-A;/CP-FP;UNIVERSITEIT VAN AMSTERDAM;NL;"UNIVERSITEIT ANTWERPEN;UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN;LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE;TARKI Tarsadalomkutatasi Intezet Zrt;UNIVERSITA DEGLI STUDI DI MILANO";"BE;IE;UK;HU;IT";"/SOC;/POL";1;0;0;1;0;0 91290;230318;ETICA;ONG;FP7-SIS;SiS-2008-1.1.2.1;FP7;Ethical Issues of Emerging ICT Applications;2009-04-01;2011-05-31;;The ETICA project will identify emerging Information and Communication Technologies (ICTs) and their potential application areas in order to analyse and evaluate ethical issues arising from these. By including a variety of stakeholders and disciplinary perspectives, it will grade and rank foreseeable ethical risks. Based on the study governance arrangements currently used to address ICT ethics in Europe, ETICA will recommend concrete governance structures to address the most salient ethical issues identified. These recommendations will form the basis of more general policy recommendations aimed at addressing ethical issues in emerging ICTs before or as they arise Taking an inclusive and interdisciplinary approach will ensure that ethical issues are identified early, recommendations will be viable and acceptable, and relevant policy suggestions will be developed. This will contribute to the larger aims of the Science in Society programme by developing democratic and open governance of ICT. Given the high importance of ICT to further a number of European policy goals, it is important that ethical issues are identified and addressed early. The provision of viable policy suggestions will have an impact well beyond the scientific community. Ethical issues have the potential to jeopardise the success of individual technical solutions. The acceptance of the scientific-technological basis of modern society requires that ethical questions are addressed openly and transparently. The ETICA project is therefore a contribution to the European Research Area and also to the quality of life of European citizens. Furthermore, ethical awareness can help the European ICT industry gain a competitive advantage over less sensitive competitors, thus contributing to the economic well-being of Europe.;1068773;828249;FP7-SCIENCE-IN-SOCIETY-2008-1;/CP;DE MONTFORT UNIVERSITY;UK;"EOTVOS KAROLY KOZPOLITIKAI KHT;FORSCHUNGSZENTRUM KARLSRUHE GMBH;STEINBEIS-HOCHSCHULE-BERLIN GMBH;Analytica Social and Economic Research Limited;TELEREGIONS NETWORK;EUREXCEL MEMBERSHIP PROJECTS LIMITED;UNIWERSYTET LODZKI;TEKNOLOGIAN TUTKIMUSKESKUS VTT;TECHNISCHE UNIVERSITEIT DELFT;EUROPEAN ELECTRONIC MESSAGING ASSOCIATION AISBL;UNIVERSITE DE NAMUR ASBL";"HU;DE;UK;BE;PL;FI;NL";"/ETH;/SCI";1;0;0;1;0;0 95117;254607;CMOIG;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IEF;FP7;Computational Modeling of Knowledge-Based Inference Generation during Reading Comprehension;2010-09-01;2012-08-31;;The proposed research project employs a pioneering interdisciplinary approach to study inference generation, a fundamental, essential cognitive process that underlies human discourse processing in general and reading comprehension in particular. By integrating linguistic computational modeling (Latent Semantic Analysis and the computational implementation of the Landscape model) with psycholinguistic theories and empirical methods (think-aloud procedures and probing techniques), I intend to explore the extent and types of knowledge-based inferences which are constructed on-line during reading. Although there is a broad consensus regarding the importance of world-knowledge in understanding discourse and achieving text coherence, there is considerable disagreement concerning this issue. Across the various theories of reading comprehension, three central views—Memory-based, Explanation-based, and Coherence-based—can be distinguished based on their conception about the content of the inferences that are activated on-line and about the nature of this process. An original theoretical framework is proposed and examined in an attempt to reconcile the conflicting findings and models under common principles. These principles concern the role of short-term working memory and long-term semantic (i.e., general knowledge) and episodic (i.e., specific text) memory associations between textual and inferred concepts. The theoretical contribution of this research to the understanding of human cognitive mechanisms and its important implications on the development of educational comprehension strategies and the design of intelligence machines that process human natural language are stressed throughout the proposal.;170535,2;170535,2;FP7-PEOPLE-2009-IEF;/MC-IEF;UNIVERSITEIT LEIDEN;NL;;;"/SCI;/EDU;/ITT";1;0;0;1;0;0 97950;263878;BISNANO;ONG;FP7-NMP;NMP.2010.1.2-4;FP7;Functionalities of Bismuth based nanostructures;2010-10-01;2013-12-31;http://www.bisnano.eu;"The aim of the present project is to explore the properties and possible applications of bismuth and bismuth based compounds when they are synthesized at the nanometric scale. This approach is motivated by the uncommon but advantageous properties of bismuth which, in part, have been exploited for many years. However, there are many unexplored possibilities and with the advent of nanotechnology new prospectives may be expected. We believe this approach will lead to new and high-tech applications of bismuth based materials, adding new value to one of the major mining products of Mexico (second most important world production) and boost the related economic benefits which at present are low. In the project, we have integrated complementary research groups from Mexico and Europe covering interdisciplinary fields. In the thematic work-packages, research groups working on the synthesis of the nanostructured materials will collaborate with others doing the physical-chemical materials characterization and the application development. The materials include Bi, Bi2O3 and Bi2S3 nanostructures, Bismuth metal oxide nanostructured ceramics and thin films, bismuth-based nanocomposites where Bi constitutes the nanoscale inclusion and the matrices varied from ceramics, polymers or glasses, and finally Bi superconductors. Extensive chemical and structural characterization will be required to correlate the synthesis parameters with the physical properties. Finally, the project includes the physical evaluation focused on the optical, electrical, magnetic, ferroelectric, etc. properties, according to the proposed applications. The time scale of the project is sufficient for the preparation of master’s degree students and the initial years of doctorate students. These students will work in a very academic-rich environment and at the same time have contact with the industrial partners in the project, some of which are leaders in the development of Bi-based commercial products.";5341196,77;1700000;FP7-NMP-2010-EU-Mexico;/CP-FP;UNIVERSITE DE PICARDIE JULES VERNE;FR;"CENTRO DE INVESTIGACIONES EN OPTICA A.C.;AVANZARE INNOVACION TECNOLOGICA SL;UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN;CENTRO NACIONAL DE METROLOGIA - CENAM;FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.;TECHNISCHE UNIVERSITAT HAMBURG-HARBURG;AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS;ISTITUTO NAZIONALE DI RICERCA METROLOGICA;SADOSA SA DE CV;UNIVERSIDADE DE COIMBRA;UNIVERSIDAD NACIONAL DE COLOMBIA;UNIVERSIDAD AUTONOMA METROPOLITANA;CENTRO DE INVESTIGACION Y DE ESTUDIOS AVANZADOS DEL INSTITUTO POLITECNICO NACIONAL;POLITECNICO DI TORINO;THE UNIVERSITY OF LIVERPOOL;INSTITUTO NACIONAL DE INVESTIGACIONES NUCLEARES;FARMAQUIMIA SA DE CV;UNIVERSIDAD NACIONAL AUTONOMA DE MEXICO";"MX;ES;IE;DE;IT;PT;CO;UK";/LIF;1;0;0;1;0;0 91151;230725;TACIT;ONG;FP7-PEOPLE;FP7-PEOPLE-IAPP-2008;FP7;Targeted Amphoteric Carriers in ImmunoTherapy;2009-08-01;2013-07-31;;"The past year has been exciting for oligonucleotide-based drug discovery and development. The Nobel Prize was awarded to Mello and Fire for discovering RNA interference. There was also big investment from the Pharmaceutical industry to Biotechnology companies-pioneers in oligonucleotide therapeutics such as Sirna, Alnylam and Isis, all US-based. High expectations were therefore raised but further progress is hampered by the issue of systemic delivery; siRNA oligonucleotides are ineffective in vivo whereas antisense DNA oligonucleotides can be effective for liver-specific targets only. Therefore, delivery systems are a matter of intense investigation with the most recent advances being cationic liposomes with PEGylation or diffusible PEGylation. However, these carriers face tolerability issues, non-specific immune stimulation or limited biodistribution. Novosom has developed a completely novel carrier system based on amphoteric liposomes. This incorporates structural features with unique charge-reversal properties which result into safety and performance advantages over the current best alternative carriers. The aim of this Consortium is to built on Novosom’s carrier technology to develop novel improved amphoteric liposomes with targeted delivery modalities to cells of the immune system, and to apply them for therapeutic oligonucleotide delivery to inflammatory diseases. Knowledge transfer between partners will facilitate the design of novel carriers, identification of targets and validation using in vivo models of inflammatory disease. The Consortium stems from two very successful one-to-one collaborations and proposes here a fully integrated program of translational, interdisciplinary research. Knowledge transfer between Novosom, a European leader in oligonucleotide delivery technologies, and two Academic Institutions of international standing in inflammatory disease therapeutics provides the competitiveness needed for a European team in this US-dominated field.";960985;960985;FP7-PEOPLE-IAPP-2008;/MC-IAPP;IDRYMA IATROVIOLOGIKON EREUNON AKADEMIAS ATHINON;EL;"PANEPISTIMIO KRITIS;NOVOSOM AG;CENIX BIOSCIENCE GMBH";"EL;DE";/EDU;1;0;0;1;0;0 99484;272976;PsySPOCUC;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-IEF;FP7;Meeting the healthcare needs of culturally diverse populations: A psycho-sociopolitical approach to cultural competence in health professionals;2011-07-01;2013-06-30;;"The main aim of this research project is to develop a model of cultural competence in health professionals, specifically based on the Portuguese context, emphasizing the complex interplay between the effects of culture and unequal power on health and healthcare with culturally diverse populations. Assuming that healthcare is often given in the context of asymmetrical power relations between professionals and users, a psycho-sociopolitical approach will be developed as a basis for the analysis and promotion of cultural competence. This approach will emphasize: (1) the underlying dynamics of power in health and healthcare in contexts of cultural and human diversity, and (2) a social-ecological approach to research and action in the field of health and healthcare with culturally diverse populations. Taking a participatory action-research approach, particular attention is paid to health needs assessment, good practices, and the empowerment of culturally diverse populations. A multi-method approach will be used, combining qualitative (focus groups with key informants, case studies based on in-depth interviews) and quantitative research techniques (mainly secondary sources and survey). Recommendations for developing interventions and policies will be put forward with the final aim of furthering the provision of adequate, accessible and quality healthcare to all the population, based on values of social justice, human development and equality. This research project is the central activity of a career development plan that will emphasize: (1) the interdisciplinary link between social psychology, community psychology and sociology; (2) the transfer of knowledge to practice; (3) a participatory community-based multi-method approach; and (4) a European perspective.";203582,6;203582,6;FP7-PEOPLE-2010-IEF;/MC-IEF;CENTRO DE INVESTIGACAO E ESTUDOS DE SOCIOLOGIA CRL;PT;;;"/EMP;/EDU;/NET";1;0;0;1;0;0 99000;272156;MDPTAR;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-IEF;FP7;Microtubule Dynamics and Protein Trafficking in Axon Regeneration;2011-07-01;2013-06-30;;'The overall aim of the proposal is to support the scientific career development of an experienced researcher, by completing an interdisciplinary research project on microtubule dynamics in axon regeneration, and enabling the fellow to acquire new knowledge and academic skills in order to attain a position of maturity and independence. The scientific objectives of the research are to analyse how the mechanisms regulating microtubule network dynamics and protein trafficking underlie the intrinsic ability of axons to regenerate after injury with the aim of improving treatment in neurological diseases such as spinal cord injury. The project will enhance the fellow’s scientific curriculum by providing advanced training in innovative and sophisticated techniques. The research training objectives are to contribute to the fellow's writing and publication skills, public presentation of her scientific results, establishment of collaborations and to learn to manage her own scientific project in a multidisciplinary environment. This will enable the fellow to compete for available funds thus, facilitating the possibility of establishing her own independent research line in Europe. The fellow’s mobility from the UK to a leading laboratory at the Erasmus Medical Center in Rotterdam, The Netherlands, will provide new points of view to perform research, scientific exchange and social interaction. This proposal is highly relevant to the 2010 Work Programme because: a) it entails genuine mobility strengthening scientific exchange between European members, b) it will increase the overall competitiveness and excellence of European science in the key field of axon regeneration and c) its innovative nature will further enhance the European Research Area making Europe more attractive to the most talented scientists from around world.';176185,6;176185,6;FP7-PEOPLE-2010-IEF;/MC-IEF;UNIVERSITEIT UTRECHT;NL;;;"/EMP;/EDU;/NET";1;0;0;1;0;0 94547;244012;MEDIATION;ONG;FP7-ENVIRONMENT;ENV.2009.1.1.6.1;FP7;Methodology for Effective Decision-making on Impacts and AdaptaTION (MEDIATION);2010-01-01;2013-06-30;;"Assessment of climate change impacts, vulnerability and adaptation requires a combination of generic and context-specific knowledge. Currently, the availability of such knowledge in Europe is fragmented and incomplete. MEDIATION addresses this challenge through six activities: (i) analysis of the decision-making context; (ii) inventory, review and improvement of methods and metrics for impacts and vulnerability analysis; (iii) likewise for costing of impacts and adaptation options; (iv) development of an overarching integrated methodology; (v) development of a flexible, interactive common platform for knowledge sharing; and (vi) dissemination of this knowledge and training. The components of the project will be connected in an iterative fashion, using case studies which combine selected regional, sectoral and cross-sectoral characteristics and policy questions. The consortium combines eleven top European scientific institutions with a high reputation and long experience in impacts, vulnerability and adaptation research and assessment. They represent different regions in Europe with contrasting vulnerabilities, cover the wide array of disciplinary and interdisciplinary knowledge required to assess sectoral and cross-sectoral vulnerabilities, already participate in numerous related European and national research programmes, and have extensive expertise in science-policy interactions. The project will establish an Advisory Group of key international scientific experts and climate change policy makers to strengthen the scientific basis of the project as well as the policy relevance. In addition to scientific innovation, MEDIATION aims at supporting national and international policy development through targeted interactions, including the UNFCCC process (notably the Nairobi Work Programme), and the EU White Paper process, the latter by systematically addressing the components of the 3rd pillar of the EU Green Paper related to knowledge development and sharing.";4050579,4;3142744;FP7-ENV-2009-1;/CP-FP;STICHTING WAGENINGEN RESEARCH;NL;"SEI OXFORD OFFICE LIMITED*STOCKHOLMENVIRONMENT INSTITUTE OXFORD OFFICE SEI LTD;SUOMEN YMPARISTOKESKUS;UNIVERSITA DEGLI STUDI DI FIRENZE;POTSDAM INSTITUT FUER KLIMAFOLGENFORSCHUNG;GCF - GLOBAL CLIMATE FORUM EV;INTERNATIONALES INSTITUT FUER ANGEWANDTE SYSTEMANALYSE;REGIONAL ENVIRONMENTAL CENTER FOR CENTRAL AND EASTERN EUROPE -REC;WAGENINGEN UNIVERSITY;UNIVERSIDAD POLITECNICA DE MADRID;JRC -JOINT RESEARCH CENTRE- EUROPEAN COMMISSION";"UK;FI;IT;DE;AT;HU;NL;ES;BE";/ENV;1;0;0;1;0;0 94633;256524;IDENTITY CODE;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-RG;FP7;Behavioural syndromes, division of labour and communication of identity in complex insect societies;2010-06-01;2013-05-31;;Animals, just like humans, differ consistently in behavioural traits such as aggressiveness, exploration, reactivity. The study of behavioural syndromes (animal personalities), defined as sets of correlated behaviours across situations, helps in explaining the evolutionary significance of individual variation. However, most studies have focussed on few model organisms with no, or relatively little, social structure. Social insects represent one of the pinnacles of social evolution. Their well-organized societies are based on an often extensive division of labour, which includes reproduction and is frequently accompanied by morphological differentiation. The extent to which this labour partitioning can be implemented depends on the efficiency of communication strategies: in particular, the communication of identity. In social insects, communication of identity involves multiple levels of recognition: inter-individual, within-colony and between-colony level. How effectively individual or group identity can be detected may depend on the behavioural type of the receiver, but this has never been explored in social insects. This project builds on the synergy between the expertise of the applicant and the host to investigate the evolutionary significance and the ontogeny of individual variation in stimulus response allowing recognition at different levels by using different species of ants, which are among the most advanced and ecologically successful animal societies. The project combines behavioural observations, chemical analysis, electrophysiology, quantitative genetics, neurobiology and cognitive studies to achieve an interdisciplinary understanding of the forces that have shaped individual behavioural variation and collective division of labour in ants. The project’s implementation will be facilitated by the applicant’s network of high-profile collaborators and will thus have a significant impact (co-operation, professional integration) and transfer of knowledge.;45000;45000;FP7-PEOPLE-2009-RG;/MC-ERG;UNIVERSITE PARIS 13;FR;;;/SCI;1;0;0;1;0;0 92568;226870;UMBRELLA;ONG;FP7-ENVIRONMENT;ENV.2008.3.1.2.1.;FP7;Using MicroBes for the REgulation of heavy metaL mobiLity at ecosystem and landscape scAle: an integrative approach for soil remediation by geobiological processes;2009-05-01;2012-04-30;;The overall goal of UMBRELLA is to use microorganisms to develop cost-efficient and sustainable measures for soil remediation at heavy metal contaminated sites throughout Europe. This will be facilitated by research in microbiology, plant uptake and (hydro)geochemistry centers on the study of microbial influence on metal biogeochemical cycles and their impact for use in soil and water protection. The technologies developed provide a speed-up of existing bioremediation techniques and will provide a tool-box to end-users with microbes for remediation actions in different European climatic, geological and biological setting which will allow low-cost, sustainable, on-site bioremediation of metal contaminations. At the same time, the introduction of a concerted, internationalized education of interdisciplinary trained PhD students across Europe will ascertain a long-lasting, sustainable education profile with relevance to soil remediation. The involvement of government agencies is focussing on the possibility to provide governments with fused guidelines for soil and water protection in a way that overcomes the practises of separated agencies by focussing on ecotoxicological risks resulting from metal contamination on-site as well as by transport through water paths in ground water and international water ways. Dissemination of results will be ensured by international congresses and publications. The management of an integrative, multi-partner consortium ensures the applicability by combination of eight sites across Europe in one modeling approach which will cover Northern, Southern, Middle and Eastern European sites to guarantee future applicability across Europe.;3136116;2337421;FP7-ENV-2008-1;/CP-FP;FRIEDRICH-SCHILLER-UNIVERSITAT JENA;DE;"LULEA TEKNISKA UNIVERSITET;UNIVERSIDAD DE VALLADOLID;UNIVERSITATEA DIN BUCURESTI;UNIVERSITAT WIEN;OSTERREICHISCHE AGENTUR FUR GESUNDHEIT UND ERNAHRUNGSSICHERHEIT GMBH;VIROTEC ITALIA SRL;UNIVERSITA DEGLI STUDI DI CAGLIARI;AGENZIA NAZIONALE PER LE NUOVE TECNOLOGIE, L'ENERGIA E LO SVILUPPO ECONOMICO SOSTENIBILE;Kwazar Corporation Sp.z o.o.;UNIWERSYTET JAGIELLONSKI;OREBRO UNIVERSITY;ABERYSTWYTH UNIVERSITY;BANGOR UNIVERSITY;HELMHOLTZ-ZENTRUM DRESDEN-ROSSENDORF EV";"SE;ES;RO;AT;IT;PL;UK;DE";"/ENV;/ESV";1;0;0;1;0;0 92317;228622;MAGNIFYCO;ONG;FP7-NMP;NMP-2008-1.1-1;FP7;MAGNETIC NANOCONTAINERS FOR COMBINED HYPERTHERMIA AND CONTROLLED DRUG RELEASE;2009-09-01;2013-02-28;http://www.magnifyco.eu;"The aim of this project is the assembly and the fabrication of a new generation of multifunctional nanostructures for performing combined hyperthermia and controlled drug release, specifically targeted to cancer cells. The “magnetic nanocontainers” we intend to develop can perform at the same time cell recognition, hyperthermia treatment, and, as a consequence of the heat and /or cell environment stimuli, the release of drug with high selectivity for ovarian carcinoma. These multifunctional tasks are made possible due to the inclusion of three main components: a) the magnetic nanoparticles, allowing detection by MRI, cancer treatment by hyperthermia and providing stimuli for drug release; b) the nanocontainers, which allow for drug encapsulation and protection from degradation, facilitate the release of the drug upon application of an external stimulus, such as heat, or an internal one, such as the acidic pH of the tumour cells; c) the antibody fragments attached to the surface of the magnetic nanocontainers to deliver them selectively to the ovarian cancer cells. The individual building blocks and their assemblies will be characterized with respect to physical, chemical, and biological features, followed by dissemination of the newly acquired knowledge. Cell culture experiments will allow to understand the performance of such nano-tools in vitro. Directed towards application in patients, in vivo animal studies will be carried out on the most successful magnetic nanocontainers. The objectives of this proposal cover a wide range of scientific fields, hence a truly interdisciplinary collaboration between chemists, physicists, and biologists is required. To this end, we propose a european network collaboration between academic partners, who will take care of the development of new solutions for nanofabrication, and industrial partners implied in the field of the proposed application who will evaluate/develop the materials and act as advisors for risks arising during the project.";4859982,14;3435956;FP7-NMP-2008-SMALL-2;/CP-FP;CONSIGLIO NAZIONALE DELLE RICERCHE;IT;"Asociacion - Centro de Investigacion Cooperativa en Nanociencias - CIC NANOGUNE;UNIVERSITEIT TWENTE;UNIVERSIDAD DE SANTIAGO DE COMPOSTELA;DOMPE SPA;UNIVERSIDAD COMPLUTENSE DE MADRID;FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA;MAGFORCE NANOTECHNOLOGIES AG;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FONDAZIONE IRCCS ISTITUTO NAZIONALE DEI TUMORI;NANOVECTOR SRL";"ES;NL;IT;DE;FR";"/BIO;/SCI;/NET;/NNT";1;0;0;1;0;0 91273;228455;NANOGOLD;ONG;FP7-NMP;"NMP-2008-2.2-2;NMP-2008-2.1-2";FP7;SELF-ORGANIZED NANOMATERIALS FOR TAILORED OPTICAL AND ELECTRICAL PROPERTIES;2009-08-01;2012-07-31;http://nanogold.epfl.ch;The NANOGOLD project aims at the fabrication and application of bulk electro-magnetic metamaterials. A promising new concept for the exploration of metamaterials is the use of periodic structures with periods considerably shorter than the wavelength of the operating electromagnetic radiation This concept allows to control the refractive properties. Making use of a bottom up approach in materials design, we will apply self-organization of organic-inorganic composite materials containing resonant entities. To tune electromagnetic properties, resonance and interference at different length scales will be implemented. In such a way we will obtain bulk optical metamaterials operating in spectral domains appropriate for photonics that can be used in applications. Our groundbreaking solution to form such artificial matter is interdisciplinary and combines inorganic chemistry, organic macromolecular synthesis, physics of electromagnetic resonances and liquid crystal technology. We start with resonant entities (metallic nanoparticles) and organize them via self-organization on the molecular scale. Systematic modular variation of the chemical entities gives access to libraries of materials which will be used to arrive at systems with desired properties. Simulation of optical properties and molecular ordering will guide the design of compounds and materials. Organization at molecular level leads to homogenous materials with optical, electronic or magnetic properties at elevated frequencies, in the visible and near infrared spectral range. The controlled utilization of the polymer physics of micro-segration, will allow for additional structuration at the nano-scale giving design freedoms to tune material properties optimally. NANOGOLD furthermore will make use of innovative fabrication techniques and processing known from liquid crystal displays by exploring new physical effects, which will result in novel devices.;4605987,98;3519235;FP7-NMP-2008-SMALL-2;/CP-FP;ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE;CH;"THE UNIVERSITY OF SHEFFIELD;UNIVERSITE DE GENEVE;RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG;VIRTUAL INSTITUTE FOR ARTIFICIAL ELECTROMAGNETIC MATERIALS AND METAMATERIALS - METAMORPHOSE VI AISBL;FRIEDRICH-SCHILLER-UNIVERSITAT JENA;UNIVERSITY OF HULL;PANEPISTIMIO PATRON;UNIVERSITA DELLA CALABRIA";"UK;CH;DE;BE;EL;IT";"/NNT;/MAT";1;0;0;1;0;0 87816;211779;SOILSERVICE;ONG;FP7-ENVIRONMENT;ENV.2007.2.1.4.1.;FP7;Conflicting demands of land use, soil biodiversity and the sustainable delivery of ecosystem goods and services in Europe;2008-09-01;2012-02-29;http://www.kem.ekol.lu.se/soilservice/index.html;European soil biodiversity is pivotal for delivering food, fiber and biofuels and carbon storage. However, the demand is greater than the amount of soil available, as production of biofuels competes with areas for food production and nature. Moreover, intensified land use reduces soil biodiversity and the resulting ecosystem services. SOILSERVICE will value soil biodiversity through the impact on ecosystem services and propose how these values can be granted through payments. SOILSERVICE will combine interdisciplinary empirical studies and soil biodiversity surveys to construct soil food web models and determine effects of changing soil biodiversity on stability and resilience of carbon, nitrogen and phosphorus cycling, as well as assess consequences for outbreaks of pests or invasive species. SOILSERVICE will link ecological and economic models to develop a system for valuing soil biodiversity in relation to ecosystem services. Objectives: • Develop methods to value soil ecosystem services during different pressure of land use and changes in soil biodiversity. • Field and modelling studies will determine to what spatial and temporal scales soil biodiversity and soil ecosystem services are vulnerable to disturbance. • Detecting processes that indicate when ecosystems are approaching the limits of their natural functioning or productive capacity. • Establishing methods to determine and predict sustainability of ecosystem services at different types of land use • Building scenarios to identify economical and social drivers of how land use such as biofuel production and land abandonment can influence soil biodiversity and ecosystem services over European scale. • Interacting with EU policies and strategies with results on which services are at threat and mitigating changes in soil biodiversity to achieve a sustainable use of soils. Our results contribute to a European knowledge-based competitive economy and to a future EU directive on soils.;4583766;3475774;FP7-ENV-2007-1;/CP-FP;LUNDS UNIVERSITET;SE;"Biologicke centrum AV CR, v. v. i.;HELSINGIN YLIOPISTO;THE UNIVERSITY OF READING;KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW;ARISTOTELIO PANEPISTIMIO THESSALONIKIS;KOBENHAVNS UNIVERSITET;SVERIGES LANTBRUKSUNIVERSITET;JUSTUS-LIEBIG-UNIVERSITAET GIESSEN;LANCASTER UNIVERSITY;WAGENINGEN UNIVERSITY";"CZ;FI;UK;NL;EL;DK;SE;DE";/ENV;1;0;0;1;0;0 95967;251978;EUPOLCON;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IEF;FP7;Conceptualizing representative democracy in the EU polity by re-thinking classical key conceptual clusters for the EU multi-level polity;2010-12-01;2014-03-24;;"Aims of the research project: The interdisciplinary project aims at a thematic set of post-Habilitation studies of the applicant in co-operation with senior scholars from the host institute. More specifically, the aims are 1) To sketch a conceptual framework for representative democracy in the European Union developed in a broad historical perspective of political thought and conceptual change through the analysis of key texts of classical and modern political thinking. The conceptual framework is constructed around three key conceptual clusters (state-government-policy-polity; parliament-representation-politicians; citizens-subjects) as thematic perspectives. There clusters are both challenged by European integration and discussed in the debates on the character of the EU. 2) To extend the methodological insights of conceptual history on the contingent and controversial character of political concepts to past and present debates on the EU as a changing polity 3) To establish a disciplinary link between conceptual history, Democratisation studies and European integration studies, supported by insights from constitutional law, philosophy, history and linguistics";177952;177952;FP7-PEOPLE-2009-IEF;/MC-IEF;JYVASKYLAN YLIOPISTO;FI;;;"/SCI;/EDU;/ITT";1;0;0;1;0;0 103249;311865;ICRI2012;ONG;FP7-INFRASTRUCTURES;INFRA;FP7;Copenhagen International Research Infrastructure Conference 2012;2011-11-15;2012-06-14;;"'The aim of the proposed activity is to support the organisation of the first International Conference on Research Infrastructure (ICRI2012), which will take place in Copenhagen on March 21-23, 2012, under the Danish Presidency of the European Council in collaboration with the European Commission (EC). The conference has its objectives in increasing international collaboration on research infrastructure in order to manage the grand challenges in today’s societies. Research infrastructures play a crucial role for the promotion of knowledge and technology and are of central importance to drive excellent science. Never before has there been a need to act globally to tackle the grand challenges before us such as climate change, health, energy supply etc.. In this new global context ICRI2012 address the following questions: Why do we need global research infrastructures? Which types of world-class infrastructures are best suited to a global approach? How to increase the use of these facilities and how to support access to them based on excellence? How to strengthen international cooperation in the implementation, governance, operation and use of research infrastructures? How to nurture synergies between research infrastructures from differing disciplines and promote interdisciplinary approach? How to manage large international Research Infrastructures focused on global challenges How to increase awareness of the education and training possibilities that Research Infrastructures offer? How to tackle data, in particular how to address the distributed nature of either the facilities themselves or the user communities? The purpose of the conference will be to make specific recommendations on how international cooperation for research infrastructures can be effective in the future. ICRI 2012 will also provide important input to the European Strategy and to the implementation of the next EU Framework Programme – 'Horizon 2020'.'";726967;220000;FP7-Adhoc-2007-13;/CSA-SA;STYRELSEN FOR FORSKNING OG UDDANNELSE;DK;;;/SCI;1;0;0;1;0;0 86444;224769;A20APOPTOSIS;ONG;FP7-PEOPLE;PEOPLE-2007-4-3.IRG;FP7;Molecular and structural analysis of A20 in the modulation of apoptosis: anti-inflammatory potential in vasculitis;2008-04-01;2012-03-31;;The ubiquitin editing protein A20, a novel 90kDa zinc-finger protein has an universal anti-inflammatory activity by inhibiting NF-kappaB activation. In endothelial cells, the induction of A20 by inflammatory stimuli renders cells resistant to apoptosis. However, A20 can have pro-apoptotic activities in other cell types. We will focus on the respective role of A20 in both endothelial cells and neutrophils, two cardinal cell players in inflammation associated with autoimmune vasculitis in which A20 could be a suitable therapeutic target and has never been investigated. We hypothesized that this differential effect of A20 in modulating apoptosis and inflammation is dependent on different molecular partner A20. Hence, we proposeto i) identify the A20 interactome by proteomic and modelisation approaches in both endothelial cells and neutrophils, ii) investigate the function of A20 in neutrophils, iii) study A20 modulation of neutrophil-mediated endothelial cell toxicity, iii) investigate A20 expression in patients with vasculitis. Through its interdisciplinary and integrative approaches combining molecular biology, cell biology, functional biology, molecular modeling and clinical investigations, this project directed by Dr Daniel, an expert of A20, constitutes a timely and novative approach to unravel the role of A20 and A20-binding proteins in modulating apoptosis and inflammation and identify novel therapeutic tools.;100000;100000;FP7-PEOPLE-2007-4-3-IRG;/MC-IRG;INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE;FR;;;"/SCI;/COO";1;0;0;1;0;0 96432;252126;MAPNE;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IEF;FP7;Mechanobiology of Aplysia neurons;2011-03-07;2013-03-06;;"Memory loss is a central symptom in different diseases such as Alzheimer’s disease, and represents a significant social and economic burden for a large percentage of European citizens. Neuronal cell adhesion molecules belonging to the immunoglobulin superfamily (IgCAMs) are known to be involved in brain development processes, and also contribute to the synaptic alterations connected with memory formation in adults. The goal of this project is to elucidate the molecular, biophysical and cellular mechanisms of directed movements of neuronal growth cones, and in particular how, upon binding to the extracellular matrix or to other cells, IgCAMs control cytoskeletal dynamics and therefore synaptic plasticity. The central hypothesis of this proposal is that adhesion-mediated growth cone guidance involves a force transduced by the cytoskeleton upon IgCAM adhesion, and that this mechanical signal further stimulates Src protein tyrosine kinase activation. In order to test this hypothesis, state-of-the-art techniques will be combined in a highly interdisciplinary manner. This project lies at the interface between mechanics, cell biology, biophysics and surface physics. The proposer will use a well-established cellular model system for growth cone studies (Aplysia), state-of-the-art molecular tools (recombinant IgCAM and Src biosensor) and a high-resolution force measurement system (Atomic Force Microscopy, AFM) coupled with FRET imaging. By applying the first molecule-specific AFM measurements to live neuronal growth cones, the proposer will measure the forces transduced by IgCAMs to the growth cone cytoskeleton and at correlating them with Src activity in real time, thereby proving the force-dependence of neuronal connectivity. This proposal is related to many of the FP7 research objectives, such as “Nanosciences, Nanotechnologies, Materials and New Production Technologies" and "Health”, specifically “Research on the Brain and Related Diseases, Human Development and Ageing”";178374,2;178374,2;FP7-PEOPLE-2009-IEF;/MC-IEF;UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN;IE;;;"/SCI;/EDU;/ITT";1;0;0;1;0;0 98936;273469;EMH;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-IEF;FP7;"""The rise and fall of military honour in Western Europe, 1789-1918""";2011-05-01;2013-10-31;;'The proposed project examines changing concepts of military honour in Western Europe between the end of the ancien régime culture of civility in the mid-eighteenth century and the advent of modern mass warfare in 1914/18. This period, as a is well known, marked an important political, economic, technological, and cultural watershed in European history. The ancillary transformation of normative codes of conduct in war on the other hand shows historiographical lacunae. Whereas a substantive corpus of literature has been written on the operationalisation of honour within nation-states, we know less about its transnational articulation from a longue durée perspective. The practice of parole d’honneur, which granted captured officers freedom of movement within or en route to their place of confinement in exchange for the promise not to escape, is a case in point. For long both sides imposed heavy social sanctions on non-conformists, but in the Napoleonic Wars and even more so the First World War there occurred partial breakdown of these practices, despite their codification in the Hague Conventions of 1899 and 1907. To address the complex reasons for the reconfiguration of military honour, my projects will develop an interdisciplinary analytical framework which draws on methodologies from history, sociology, and international relations.';170401,6;170401,6;FP7-PEOPLE-2010-IEF;/MC-IEF;UNIVERSITAET BERN;CH;;;"/EMP;/EDU;/NET";1;0;0;1;0;0 94621;256474;BACTERIAL COLONY SIM;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-RG;FP7;Multiscale modeling and simulation of bacterial colonies;2010-06-01;2014-05-31;;Some bacteria are known to grow in colonies that form complicated geometrical patterns. In order to develop such a colony, bacteria will sense and respond to their local environment by secreting and absorbing peptides, proteins, pheromones and other chemotactic or quorum sensing molecules. Furthermore, under adverse conditions, bacteria can sporulate, alternate its shape, or look for better DNA. Past work has focused mainly on the biological aspects involved in these processes. However, much less is known on the dynamics of the colony as a whole. In particular, the dynamics of the colony may be completely different than that of the single cell and it is not clear how the bacterial activity at the microscopic scale is related to the collective macroscopic behavior. A recent mathematical model that I developed explains an interesting experiment in which sibling bacterial colonies grown on low-nutrients plates mutually kill each other through secretions released to the media. Simulation results where compared with experimental data. The work was recently submitted to PNAS. The purpose of the proposed research is to develop new and improved models and innovative simulation methods for connecting between the microscopic behavior of individual bacteria and that of the colony as a whole. New algorithms are developed in order to solve the models numerically. Such an interdisciplinary research is crucial for understanding complex biological phenomena. There are many interesting and important directions for future research. For example, new experiments suggest that surface tension may play a key role in the dynamics of the colony. Another example is the addition of newly discovered knowledge on the mechanism bacteria use to decide between sporulation (going into a dormant phase) and competence (mutation into a different form of strand).;100000;100000;FP7-PEOPLE-2009-RG;/MC-IRG;BAR ILAN UNIVERSITY;IL;;;/SCI;1;0;0;1;0;0 103302;298811;EPOQUES;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IEF;FP7;Exciton-Polariton Optoelectronic and Quantum Employment in Semiconductors;2012-03-01;2014-02-28;;"'Both electrons and photons have emerged as essential particles in our information age. Electrons interact strongly with each other and form the basis for computational architectures, while photons interact weakly and are the ideal candidates for communication. While the strength of each particle can also be viewed as a weakness, an emerging research field has focused on the fundamental physics of hybrid particles between electrons and photons. Known as exciton-polaritons, such particles can be generated in solid-state nanostructures such as semiconductor microcavites. Naturally, exciton-polaritons exhibit a mix of properties of electrons and photons and recent fundamental studies have revealed their Bose-Einstein condensation, superfluidity and a rich spin dynamics. With a range of basic physical effects now known, the potential for constructing devices from these hybrid particles has appeared, yet remains largely unstudied. Optical or electrical spin control of exciton-polaritons has a perspective for information processing, where the strong non-linear interactions between excitons could be sufficient for a complete logical functionality. Going beyond classical effects, exciton-polaritons are quantum particles and seem to be realistic candidates for quantum information processing. Unfortunately the field of exciton-polariton physics has evolved rather separately from the field of quantum information science, likely due to the difficulty in applying the most basic ideas of quantum information theory to exciton-polaritons. Namely, it is not known how to isolate exciton-polaritons as qubits (since they are bosons) such that more advanced schemes based on continuous variables are required. The aim of this project is to design and study theoretically exciton-polariton based devices. To understand the promise and limitations of these particles an interdisciplinary project between condensed matter physics, quantum optics and quantum information theory is essential.'";185763,6;185763,6;FP7-PEOPLE-2011-IEF;/MC-IEF;MEDITERRANEAN INSTITUTE OF FOUNDAMENTAL PHYSICS ONLUS;IT;;;/SCI;1;0;0;1;0;0 91272;228346;LEARNFORM;ONG;FP7-NMP;NMP-2008-3.2-2;FP7;Self-Learning Sheet Metal Forming System;2009-04-01;2012-03-31;http://www.learnform.eu;The automotive and white goods market tends towards individual customer solutions with product variants in small batch production, for which the forming system needs special setups, parameter change in self-learning control systems and high skilled operators. The self-learning sheet metal forming system LearnForm aims at an innovative knowledge-based drawing process with integrated multi sensors and actuators for adapting the control system strategy to changed material properties and product variants. The concept of the project LearnForm bases on the following main ideas: 1) a self-learning sheet metal forming system based on work piece energy and thermal quality control, 2) intelligent drawing dies including multi-sensors, 3) multi die cushion axes with adaptronic force oscillation actuators and 4) an open architecture motion control system extended by self-learning control strategies. Three tasks of self-learning control are the sliding friction, forming and clamping tasks supervised by the energy level with thermo camera quality check. Demonstrators are intelligent drawing dies for automotive and white goods and self-learning process control software with multi criteria optimizing strategies. The industrial leadership is performed by 5 companies (3OEM, 2SME) with their market leader knowledge and product programme. RTD partners co-operate with outstanding applied and basic interdisciplinary research experience. The work packages include simulation, measuring, programming, training and testing tasks. The project consortium has estimated the high RTD risk and total project costs to 4.77M€. The total project exploitation from 8 partners is estimated to 25M€ in the third year. The impact from the LearnForm results in the European market of knowledge-based sheet forming presses and dies, industrial process control is characterized by an annual increased turnover of 57.4M€ and by annual reduced manufacturing costs in automotive and white goods of 49.9M€.;4766379,32;3410000;FP7-NMP-2008-SMALL-2;/CP-FP;FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.;DE;"Gorenje Orodjarna, d.o.o., Velenje, Partizanska 12;FUNDACION TECNALIA RESEARCH & INNOVATION;ERAS GESELLSCHAFT FUER ENTWICKLUNG UND REALISATION ADAPTIVER SYSTEME MBH;FUNDACION CIE I+D+i;CEDRAT TECHNOLOGIES SA;CESKE VYSOKE UCENI TECHNICKE V PRAZE;SIEMENS AKTIENGESELLSCHAFT";"SI;ES;DE;FR;CZ";"/SCI;/IND";1;0;0;1;0;0 102430;295211;MIGMEDCIS;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IRSES;FP7;"""The comparative analysis of the economic aspects of international migration: EU, Mediterranean, and CIS""";2012-02-01;2014-01-31;;"'The overall objective of the project is to bring together an international and interdisciplinary research teams for the purpose of forming a center for research and transfer of knowledge in the area of international migration. Migration is an international phenomenon that transcends national boundaries. It is no longer limited to only few areas of the world, with many new migration systems having established themselves over the last 20 years. The project will take predominantly economic and socio-economic perspective. The team will commence its work from a clear standpoint: migration phenomena are similar across the world and there are many tools to investigate them that can be used successfully in various geographic areas. Promoting universal scientific approach, the project is going to trespass geographical and political fragmentation of this study area. Instead it will focus on commonalities across three migration systems: ? European Union – Mediterranean countries ? Russian Federation – Commonwealth of Independent States ? European Union – Commonwealth of Independent States The exchange program will facilitate the following technical cooperation: 1. Exchange of expertise as regards measurement of various types of money transfers and their impact; 2. Exchange of expertise on researching criminal activities in labour market in various migration systems; 3. Exchange of experience in analyzing of the factors determining the formation of the centres of labour gravity and sharing the methodology of estimating the dynamics of human capital flows. In order to achieve these aims, the partners will engage in five work packages that will include both research collaboration and hands-on experience. The first will be achieved through interactive exchanges and structured seminars and workshops, as well as supporting lectures; the second will be achieved by focused field visits.'";38000;38000;FP7-PEOPLE-2011-IRSES;/MC-IRSES;EUROPEAN UNIVERSITY INSTITUTE;IT;UNIVERZITA KARLOVA;CZ;/SCI;1;0;0;1;0;0 96016;253694;EOS;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IEF;FP7;European Orientalisms;2010-09-20;2012-09-19;;"The overall aim of this project is a comparative study of German and English Orientalist discourses – Western modes and categories of thinking about the Orient – between 1500 and 1650. The central issue addressed here is whether the German and English experiences of the Orient in this period, more specifically encounters with the Ottoman Empire, differed and, in turn, produced other kinds of Orientalism. This is an important project for a number of reasons: firstly, it will examine the viability of the prevalent concept of Orientalism as it was first formulated by Edward Said; secondly, the project addresses a gap in the existing research by providing not only the first Anglo-German comparative study on the subject, but will also synthesise the different scholarly approaches to the field towards a poetics of Orientalism. The questions Orientalism addresses are, among other things, concerned with Europe’s understanding of Islamic cultures; thus, a third important reason for this study is that it will trace and analyse some of the earliest debates and experiences of these encounters. Such a historical narrative is crucial if we are to understand Europe’s relationships with its Islamic neighbours today. While my own research expertise is on early modern English Orientalism, this project depends substantially on further archival research in Germany, Austria and England. An interdisciplinary undertaking combining literary and historical approaches, the results of this project represent an innovative reappraisal of an established problem, by bringing to consciousness some of the finer, neglected strategies that inform geographically specific Orientalisms.";170174,2;170174,2;FP7-PEOPLE-2009-IEF;/MC-IEF;UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK;IE;;;"/SCI;/EDU;/ITT";1;0;0;1;0;0 103582;300038;UNIGEMS;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IEF;FP7;"""Synthetic Biology Resources for Universities: Research, development and implementation of resources for teaching synthetic biology""";2012-05-01;2014-04-30;;"'Synthetic biology is an emergent interdisciplinary field that brings chemists, geneticists and microbiologists together with designers of electronic circuits, researchers of digital signal transmission and complex system interactions. It applies engineering principles such as the standardisation of parts and their organisation into complex circuits to recombinant DNA techniques. Its goal is to create organisms with desirable characteristics. Synthetic biology is also a valuable research tool used to elucidate the function of biological systems and inform their modification. UNIGEMS aims to select and create a compatible and extensible set of curated synthetic biology resources, develop them into low-cost packages of equipment and materials to assist in synthetic biology training and deliver practical courses for university students. The materials will form an entry point to expansion, modification and generation of synthetic systems, open to students’ and lecturers’ ’ ideas. UNIGEMS’ core set of curated resources will advance the understanding of synthetic biology techniques, its limitations and advantages, the ethical consequences of its use and its impact on society. It will promote wider engagement in synthetic biology in universities across Europe. The project combines: 1) Laboratory research in a cutting-edge field, developing and testing synthetic biology parts and modules; 2) Product development in preparing low-cost, laboratory-ready kits; 3) Preparing, overseeing, conducting and analysing an inquiry-based practical synthetic biology course for undergraduate students. The UNIGEMS project will allow the Fellow to gain expertise both in new research fields (bacterial genomics and physiology and engineering principles) and new science education experiences (product development, preparing and providing educational content for undergraduates). All of these experiences will enable him to set up his own gorup in Poland after completion of the project.'";209033,4;209033,4;FP7-PEOPLE-2011-IEF;/MC-IEF;THE UNIVERSITY OF READING;UK;;;/SCI;1;0;0;1;0;0 89133;230683;ASIANPOPCULTURES;ONG;FP7-PEOPLE;PEOPLE-2007-4-3.IRG;FP7;Popular Culture and Regionalization in East and Southeast Asia;2008-10-01;2012-09-30;;Over the last two decades, Japanese, Chinese, and Korean popular culture products have been massively exported, marketed, and consumed throughout East and Southeast Asia. A wide variety of these products are especially accessible and readily apparent in the region’s big cities. Concurrently, regional collaborations in the production and marketing of movies, music, animation, and television programs are also having a strong impact on the local cultural markets. These productions are initiated by entrepreneurs in search of new business expansion opportunities in this region’s emerging consumer-driven markets. By employing an interdisciplinary approach that breaches the barriers that separate the social sciences from the humanities, this project will examine cultural aspects of regionalization in East and Southeast Asia. The research itself focuses on the process by which confluences of popular culture have diffused throughout markets in this region in the period surrounding the 1990s, the concurrent formation of what I call “regional media alliances”, and the corresponding policies initiated by the state toward the production and export of culture. The purpose of this study is to explore the connection between the commodification of culture and the dynamics of regionalization by examining the activities of the popular culture industries in East and Southeast Asia over the last two decades. An attempt is made to go beyond state-centric explanations of regionalization and develop a theoretically plausible account for the way commodified culture affects regional formation.;100000;100000;FP7-PEOPLE-IRG-2008;/MC-IRG;THE HEBREW UNIVERSITY OF JERUSALEM;IL;;;"/SCI;/COO";1;0;0;1;0;0 88220;200755;EUCAAD;ONG;FP7-HEALTH;HEALTH-2007-1.4-1;FP7;European Consortium for Anticancer Antibody Development;2008-05-01;2012-04-30;;Cancer is the second leading cause of death in European countries, and one of the most imminent health problems in the developed world. Innovative, so-called targeted therapies are urgently needed that aim specifically at cancer cells or to cells of the stroma that support tumor growth. The ultimate goal of a targeted therapy is to increase anti-tumor efficacy with lowest possible side effects. Rapid and efficient translation of basic scientific advances into reagents, and targeted molecular leads for preclinical and clinical research and development based on scientific rationales and state-of-the-art technologies, optimally requires an interdisciplinary, collaborative, team-oriented approach. EUCAAD represents a virtual research institute in Europe and consists of 9 research participants including 4 SMEs devoted to the discovery and evaluation of new antibodies for therapy of human cancers. The consortium consists of researchers from SMEs and scientific and clinical centres that have gained international acclaim in this area of research, many of who have worked together in previous EU funded applications e.g. ANGIOSTOP, EUCAPS, ESTDAB and ENACT. Within the consortium there is unique expertise regarding target discovery, target validation, antibody production and initiation of clinical trials. As part of its efforts to translate laboratory research into viable cancer therapies the individual partners has accumulated an extensive portfolio of intellectual property providing a competitive edge to this application. The focus of the grant is the development and evaluation of antibodies against new target structures on tumour cells and blood vessels supplying tumours which are responsible for tumour angiogenesis, progression and metastasis. Collectively, the activities of this consortium can improve the cancer treatment standards in Europe and provide economic benefit to European biotechnology and pharmaceutical research by providing novel immunopharmaceuticals.;7862359,53;5989862;FP7-HEALTH-2007-A;/CP-FP;KAROLINSKA INSTITUTET;SE;"THROMBOGENICS NV;MARTIN-LUTHER-UNIVERSITAET HALLE-WITTENBERG;PROTAGEN AG;UNIVERSITA DEGLI STUDI DI TORINO;UNIVERSITA DEGLI STUDI GABRIELE D'ANNUNZIO DI CHIETI-PESCARA;BIOINVENT INTERNATIONAL AB;UNIVERSITE D'AIX MARSEILLE;PHILOCHEM AG";"BE;DE;IT;SE;FR;CH";"/BIO;/MED";1;0;0;1;0;0 96240;252518;GRAWINAE;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IEF;FP7;GRANARIES AND WAREHOUSES IN NORTH AFRICA AND EGYPT DURING THE ROMAN AGE. TYPOLOGY, BUILDING TECHNIQUES, FUNCTION, PRODUCTIVE CONTEXT;2010-10-01;2012-09-30;;"The present project aims at presenting an interdisciplinary way of looking at the history of the African grain in Roman age, in particular from the 1st century BC to the 5th century AD, starting from the data that can be found at archaeological level. The project of starting a new research arises from the lack of a comprehensive study, sufficiently updated and complete, considered all noticeable evidence emerged from the excavations of the past forty years. The present study intends to develop and to deeply investigate grain provision in the Roman provinces of the Mediterranean coasts/shores in North Africa (actual Morocco, Algeria, Tunisia, Libya, Egypt), shifting the perspective to the study of granaries as containers, to their technological aspects and productive contexts. The matter of this project will be techniques of construction, interior arrangement/layout, storage system, evaluation of thermo-igrometric conditions, grain species, climatic conditions, lithology and pedology of the soils. Where were the store buildings located? Who built them and which were the architectures and techniques used? How were the seeds preserved? How was the production organized? Which were the best soils? Which were the cultivated species? The innovation of the project consists in using different methodologies: archaeological investigation; stratigraphic analysis and application technologies; geophysical prospection (magnetic method); use of the custom-made softwares to calculate storage capacity of the building and to evaluation of thermo-igrometric conditions. During the project will be carried out the geoarchaeological study (paleo-environmental conditions of the site, dynamics and the evolution of soils) and the anthropological investigation of traditional storage system. Another important aspect of this project is to understand the grain commerce that was developed at regional level and at a long distance level.";222230,4;222230,4;FP7-PEOPLE-2009-IEF;/MC-IEF;UNIVERSITE D'AIX MARSEILLE;FR;UNIVERSITE DE PROVENCE;FR;"/SCI;/EDU;/ITT";1;0;0;1;0;0 104179;291722;IFP TRANSCURE;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-COFUND;FP7;TransCure - International Fellowship Program on Translational Research;2012-05-01;2017-04-30;;"'The herein proposed International Fellowship Program will be integrated into the recently funded Swiss translational research program, the National Center of Competence in Research (NCCR) TransCure, a joint research effort of 28 academic research groups located in major Swiss universities. The aim of the NCCR TransCure is to improve prevention and treatment of chronic diseases such as cancer, osteoporosis, neurodegenerative diseases, heart diseases, etc. Recent progresses in biomedical research have revealed that the dysfunction of specific membrane proteins contributes to the pathogenesis of these diseases. NCCR TransCure aims at studying the function of implicated membrane proteins and developing innovative drugs that control them in the diseased state. Membrane transport proteins and ion channels are particularly important pharmaceutical targets as they are the gatekeepers of the membranes of cells and cell organelles. In particular, they control the uptake and efflux of vital substances such as sugars, vitamins, trace elements, signal molecules and drugs. Targeting these proteins has been rather neglected yet by the pharmaceutical industry due to their structural complexity and hydrophobic nature. Thus, these proteins represent a large and unexplored pharmaceutical wealth. The TransCure premise is that integration of medicine, structural biology and chemistry will be tremendously beneficial in accelerating the translational avenue from 'gene to drug'. The future success of translational research in Europe depends on well-trained and multidisciplinary-oriented young researchers. The Swiss interdisciplinary TransCure research network represents the ideal platform for the training of such researchers from Europe and all over the world. Therefore, an integration of this COFUND IFP into TransCure will provide Europe with the long-sought 'next generation biomedical scientists', necessary for the development of the 'next generation therapeutic drugs' in the future.'";6438522;2575408,8;FP7-PEOPLE-2011-COFUND;/MC-COFUND;UNIVERSITAET BERN;CH;;;/SCI;1;0;0;1;0;0 98523;274677;ECSOMS;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-IIF;FP7;Exploiting Chemical Self-Organisation in Materials Science;2012-01-01;2013-12-31;;"'From molecules and cells to whole organisms, self-organising behaviour emerges from the interaction of components. The most beautiful examples of self-organisation occur in biological systems, where the combination of non-equilibrium chemistry and physical processes in confined environments give rise to complex but ordered structures. A current challenge for physical scientists is to mimic biology for the creation of complex patterned materials that might act as functional catalytic surfaces, novel materials or devices for the healthcare industries such as synthetic tissue. The purpose of this project is to develop new technologies for the generation of patterned materials. For the creation of spatial order, a mechanism proposed by Alan Turing in 1952 as a chemical basis for morphogenesis will be exploited. In this seminal work, he demonstrated theoretically how reaction and diffusion combine to create a chemical pre-pattern for the growth of form in biological systems. Now the robust formation of microscale spots, stripes and labyrinth-type patterns has been reported in flow reactors containing gels/membranes. We design novel flow reactors to generate the first Turing patterns on curved surfaces using porous tubes or particles as support. The patterns will trigger polymerisation processes by using, for example, acid concentration patterns coupled with acid catalysed polymerisation to obtain micro-patterned tubes or spheres. Part of the research will also involve developing bio-compatible routes to micropatterned materials by use of enzyme-catalysed reactions. The project is highly interdisciplinary, combining the physical sciences and engineering. It will also provide insight to the role of curvature on biological pattern formation driven by reaction-diffusion mechanisms; an important area of exclusively theoretical research.'";201049,6;201049,6;FP7-PEOPLE-2010-IIF;/MC-IIF;UNIVERSITY OF LEEDS;UK;;;"/SOC;/COO";1;0;0;1;0;0 88631;212692;SPIRAL2PP;ONG;FP7-INFRASTRUCTURES;INFRA-2007-2.2-01;FP7;SPIRAL2 PREPARATORY PHASE;2007-11-01;2012-03-31;;The SPIRAL 2 Preparatory Phase project aims to achieve the development and signing of the consortium agreement allowing for the construction of the facility. The SPIRAL 2 project located at the GANIL facility (Caen, France) will deliver energetic rare (radioactive) isotope beams with intensities not yet available with presently running machines. The studies of the properties of nuclei forming these beams or their interaction with stable nuclei is a rapidly developing field of contemporary nuclear physics, astrophysics and interdisciplinary research. Although the Region Basse-Normandie and the French funding agencies (CNRS and CEA) are financing the investment to the extend of 80% of the cost of baseline project, SPIRAL 2 seeks new partners in order to balance the construction budget both of the baseline project and of the new instrumentation necessary for experiments. The Preparatory Phase will deal with the critical financial, legal and organisational issues related to the international character of the SPIRAL 2 facility during its construction and operation phases. Searching for new funding partners will be achieved by direct contacts and negotiations between international partners, their funding agencies and the European Commission as established through the official visits, meetings and workshops. Several critical technical issues have still to be addressed in order to construct the SPIRAL2 facility and associated instrumentation. The corresponding tasks were chosen in order solve remaining technical challenges as well as to attract efficiently European partners. In particular, the accent was put on the new instrumentation for SPIRAL 2. This topic, being the most attractive for scientists, is an excellent tool to convince the funding agencies of international partners to commit for the construction phase. The attractiveness of SPIRAL 2 for outside users will be improved by the construction of new infrastructures.;8767158,97;3900000;FP7-INFRASTRUCTURES-2007-1;/CP-CSA-Infra;GRAND ACCELERATEUR NATIONAL D'IONS LOURDS;FR;"SOREQ NUCLEAR RESEARCH CENTER;FRIEDRICH-ALEXANDER-UNIVERSITAET ERLANGEN NUERNBERG;WEIZMANN INSTITUTE OF SCIENCE;COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES;SOFIISKI UNIVERSITET SVETI KLIMENT OHRIDSKI;UNIVERSIDAD DE HUELVA;THE HENRYK NIEWODNICZANSKI INSTITUTE OF NUCLEAR PHYSICS, POLISH ACADEMY OF SCIENCES;GSI HELMHOLTZZENTRUM FUER SCHWERIONENFORSCHUNG Gmbh;INSTITUTE OF NUCLEAR RESEARCH AND NUCLEAR ENERGY - BULGARIAN ACADEMY OF SCIENCES;CENTRO DE INVESTIGACIONES ENERGETICAS, MEDIOAMBIENTALES Y TECNOLOGICAS-CIEMAT;Magyar Tudomanyos Akademia Atommagkutato Intezete;FORSTER BAU GMBH INGENIEURGESELLSCHAFT;SCIENCE AND TECHNOLOGY FACILITIES COUNCIL;UNIVERSITY OF YORK;USTAV JADERNE FYZIKY AV CR;KARLSRUHER INSTITUT FUER TECHNOLOGIE;COOPERATIVE METROPOLITAINE D ENTREPRISE GENERALE SA;THE UNIVERSITY OF LIVERPOOL;RIJKSUNIVERSITEIT GRONINGEN;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;KATHOLIEKE UNIVERSITEIT LEUVEN;UNIVERSITY OF SURREY;""INSTITUTUL NATIONAL DE CERCETARE -DEZVOLTARE PENTRU FIZICA SI INGINERIE NUCLEARA """"HORIA HULUBEI"""" (IFIN-HH)"";ISTITUTO NAZIONALE DI FISICA NUCLEARE";"IL;DE;FR;BG;ES;PL;HU;UK;CZ;NL;BE;RO;IT";/SCI;1;0;0;1;0;0 89012;214627;DYNACOP;ONG;FP7-PEOPLE;PEOPLE-2007-1-1-ITN;FP7;DYNamics of Architecturally COmplex Polymers;2009-02-01;2013-01-31;;"The scientific objective of DYNACOP is to obtain a fundamental understanding of the flow behaviour and the dynamics of blends of topologically complex macromolecular fluids and their role in processing and properties of blends. These materials exhibit complex dynamics and rheology and, in many cases, show hierarchical relaxation over many different timescales. This in turn affects the processing and properties of the final materials. In order to rationally design appropriate materials and processes for various technological applications, a rigorous, knowledge based approach is needed. This is especially urgent in the face of current opportunities offered by tailored molecular engineering of polymers at the industrial scale, and the proposed use of these materials in nano-structured composites for smart applications in devices, electronics ad high-performance applications. The training objective of the proposed action is to provide young post-doctoral researchers with the necessary interdisciplinary knowledge and experience in the field of soft materials properties, much needed throughout Europe, which will allow them to address some of the many scientific and technological challenges in the field. This will first and foremost be achieved through a collaborative research program and portfolio of training courses intimately linking industry and academia. To ensure fruitful collaborations, the participating research groups will work around a limited number of model systems; exchange the samples, and apply to them the techniques and/ or theoretical approaches developed in the different laboratories. The research groups are selected in order to obtain the needed synergy, as they have different backgrounds/expertise, in physics, chemical engineering, chemistry and materials science. 6 Very high profile international visiting scientists, bringing their uniques expertise to Europe, will participate in the training and research.";3493688,76;3493688,76;FP7-PEOPLE-2007-1-1-ITN;/MC-ITN;UNIVERSITY OF LEEDS;UK;"DOW BENELUX BV;FORSCHUNGSZENTRUM JULICH GMBH;ETHNIKO KAI KAPODISTRIAKO PANEPISTIMIO ATHINON;UNIVERSITY OF DURHAM;UNIVERSITEIT TWENTE;UNIVERSITA DEGLI STUDI DI NAPOLI FEDERICO II.;FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS;UNIVERSITE CATHOLIQUE DE LOUVAIN;BASF SE;DANMARKS TEKNISKE UNIVERSITET;UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA";"NL;DE;EL;UK;IT;BE;DK;ES";"/EMP;/SOC;/EDU";1;0;0;1;0;0 91052;225670;MEDEA;ONG;FP7-SSH;"SSH-2007-2.2-01;SSH-2007-4.1-02";FP7;Models and their Effects on Development paths: an Ethnographic and comparative Approach to knowledge transmission and livelilhood strategies;2009-07-01;2012-06-30;http://www.medeasteelproject.org/;The project interrogates the impact of development paths on the livelihoods and life projects of citizens. Starting from the premise that the analysis of (dominant or alternative) development paths must be situated within the complexities of historically unfolding links and realtionships, we shall explore how they are 'practiced' in specific environments. Central questions address: 1) How development models interact with specific socio-economic contexts 2) The effects of these interactions on transmissions and innovation of knowledge/skills 3) How specific development paths affect livelihood strategies. An interdisciplinary approach combines qualitative research and comparative methodologies with modelling to explore the dynamic effects of development models as they are implemented in specific contexts, at micro and macro levels. We hypothesise that: a) There is a lack of fit between the formal design of development models and their concrete applications. b) The transmission of knowledge/skills is central to effective development. c) Knowledge/skills (both tacit and explicit) are transmitted through formal and informal mechanisms, for example between gender and generations in families and neighbourhoods. d) Political and economic disruptions constitute situations of crisis in this transmission but at the same time afford opportunities for innovation. Focusing on connections between skills, work and unemployment in relation to heavy industry, the research will identify critical points in the shifts in demand for knowledge across generations, regions and economic spheres. An ethnographic approach enables a detailed account of social networks (encompassing those of solidarity and support) within and beyond work places, including strategic friendship, kinship and neighbourhood relations. The project will thus contribute to the comparative analysis of development models, and will generate recommendations for more complex and context-sensitive approaches.;1426692;1100322;FP7-SSH-2007-1;/CP-FP;GOLDSMITHS' COLLEGE;UK;"Instituto de Desarrollo Economico y Social;FUNDACAO UNIVERSIDADE DE BRASILIA;UNIVERZITA KOMENSKEHO V BRATISLAVE;UNIVERSITAT DE BARCELONA;ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA";"AR;BR;SK;ES;IT";"/REG;/SOC;/ECO";1;0;0;1;0;0 92506;230845;WARECALC;ONG;FP7-PEOPLE;FP7-PEOPLE-IRSES-2008;FP7;WATER RESOURCES VULNERABILITY TO CLIMATE AND ANTHROPOGENIC LANDSCAPE CHANGES;2009-04-15;2013-04-14;;Climate projections and trend analysis of historical data suggest that precipitation and temperature changes can dramatically alter the supply of and the demand for water in the human- and eco-systems. Moreover, anthropogenic landscape changes are occurring at unprecedented scales and rates given the societal needs for various (and often competing) ecosystem goods and services (food, energy, and water). How stable or resilient are the human- and eco- systems to climatic and anthropogenic perturbations remain a major societal concern. Of these concerns, hydrologic cycle changes, water resources availability and related management rank among the highest because of their importance in regulating human and ecological sustainability and climate feedbacks. A number of recent studies suggest that continental runoff increased throughout the 20th century despite a rapid increase in water consumption by humans and their activities. Scope of the project: The goal of this research program is on the overall impact of such changes on rainfall (the source of water) and concomitant replenishment of usable water supplies (e.g. ground- and stream- water) given their high priority to any future water resource planning. Even within this restricted scope, the barriers to scientific progress are numerous necessitating an inter-disciplinary approach that combines principles from eco-hydrology, hydraulics and fluid mechanics, soil physics, plant physiology, stochastic processes, dynamical systems theory, and water resources management. This project aims to build a network of researchers with complementary talents to begin progress on these fronts. Moreover, this network of researchers will be actively engaged in preparing the next generation of international scientists (via graduate student exchanges) who will be trained to approach such ‘interdisciplinary’ societal problems and progress on them by adopting ‘trans-disciplinary’ approaches now emerging from complex systems science, dynami;90000;90000;FP7-PEOPLE-IRSES-2008;/MC-IRSES;POLITECNICO DI TORINO;IT;;;/EDU;1;0;0;1;0;0 92449;236836;MAPBYADMIXTURECHL;ONG;FP7-PEOPLE;FP7-PEOPLE-IOF-2008;FP7;Mapping Genes involved in Psychiatric Disorders by Admixture Linkage Disequilibrium in Chilean populations;2009-08-01;2012-07-31;;Psychiatric disorders show a complex pattern of inheritance with genetic and environmental factors influencing disease risk. Despite the existence of numerous association studies aiming to identify genetic variants involved in these disorders, inconsistencies in replication studies are common and just a few examples of links between gene variants and psychiatric disorders have been accepted. Several factors may be underlying the failure on replication: difficulties on the definition of clinical phenotypes, existence of distinct disease incidences or disease susceptibility variants among populations and, finally, differences in Linkage Disequilibrium and allele frequencies because of diverse population history. Whole genome association studies (WGAS) are powerful methods to map disease genes, however, these expensive techniques have been unsuccessful for psychiatric disorders. An alternative approach could be the use of mapping by admixture linkage disequilibrium (MALD), an efficient and economical method to localize disease-causing variants between two historically separated populations. MALD has already been successful for identification of disease loci in African American populations and, similarly, it is hoped to be a powerful tool in Latin American populations. We propose the design of an admixture panel of SNPs to map susceptibility genes for psychiatric disorders, particularly substance use and attention-deficit hyperactivity disorders, by the analysis of native (Aymara) and recently admixed populations from Chile. Furthermore, we also plan to assess the repercussions that different genetic structures among populations may have on the interpretation of association studies and, finally, we will search for signals of natural selection and adaptation pinpointing potential genes affecting behavioural traits. This collaborative and interdisciplinary project will also focus on the anthropological and cultural implications of the research and results obtained.;272968,4;272968,4;FP7-PEOPLE-IOF-2008;/MC-IOF;UNIVERSIDAD POMPEU FABRA;ES;;;"/COO;/EDU";1;0;0;1;0;0 101541;275071;DIOGENES;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-IIF;FP7;Dust Impacts on Glaciated Environments;2012-03-01;2014-02-28;;'This interdisciplinary project addresses impacts of mineral aerosol (dust) on glaciers bringing together two major issues in climate change research: glacier shrinkage and impacts of mineral aerosol on climate system. The project is set in the Caucasus Mountains, Russia and will bring together models and observations of dust deposition and glacier melt using a variety of techniques. The project’s objectives can be grouped into three sets. The first set deals with characterisation of dust deposited on glaciers and its radiative properties. Detailed characterisation of dust including elemental composition and particle size distribution will be provided and sensitivity of glacier melt to dust deposition will be quantified discriminating between dust of different type and provenance (e.g. locally-produced (LPD) and long-travelled (LTD)) and using energy balance melt models. A novel methodology to derive reflectance and quantify the extent and density of dust deposited on glacier surface will be developed using hyperspectral remote sensing. The second set deals with LTD. A record of LTD deposition events will be established using samples collected from the Caucasus glaciers since 2008. The project will make use of samples from the deep ice-core extracted in the study region in 2009. Trends and key meteorological controls over LTD deposition will be quantified and dust provenance will be determined. The third set deals with representation of LTD deposition in HiGAM atmospheric general circulation model and its validation. Model data characterising LTD transportation and deposition in the Caucasus will be retrieved from the 20-year model runs and validated against observations generated by the project helping to improve model performance. The project will bring to the EU new observational data and expertise in glacier change in the region where environmental security depends on glacier runoff and will benefit from the advanced techniques which are unavailable in Russia.';209092,8;209092,8;FP7-PEOPLE-2010-IIF;/MC-IIF;THE UNIVERSITY OF READING;UK;;;"/SOC;/COO";1;0;0;1;0;0 89726;223692;CHERISH;ONG;FP7-HEALTH;HEALTH-2007-2.2.1-10;FP7;Improving Diagnoses of Mental Retardation in Children in Central Eastern Europe and Central Asia through Genetic Characterisation and Bioinformatics/-Statistics,;2009-02-01;2012-07-31;http://www.cherishproject.eu/;Mental retardation (MR) is a highly heterogeneous disorder and is of genetic origin in about 50% of the cases. Despite recent progress in research the causes and the pathophysiology of MR remains obscure. It is essential to investigate this in order to develop future diagnostic and therapeutic strategies. The overall goal of this proposal is to establish an interdisciplinary Eastern Europe and Central Asia (EECA) consortium of experts with a joint programme of activities to generate knowledge about MR and the structure and dynamics of the brain as such. This project will be the first to study in depth the prevalence and incidence of MR in EECA . The objectives of the CHERISH project are to: - to develop a standardized approach for MR diagnosis through clinical workshops and courses - to create a large data-base of patients with clinically well defined MR, both syndromic and non-syndromic - identify cryptic genomic rearrangements through molecular cytogenetic analysis - sequence MR genes and analyse the molecular epidemiology of MR in Eastern European populations - develop diagnostic tools for recurrent/common mutations - identify new MR genes in X-linked and autosomal recessive forms of the disorder - increase awareness on the possible genetic origin of MR and implications for novel therapeutic strategies The project partners will join forces to create a large collection of samples and a database from MR patients which will be become the reference. All institutions involved are the referral centres for MR in their respective countries. The molecular studies will be performed in technologically-advanced genetic laboratories. A straightforward outcome of CHERISH will lay the basis for a significant improvement of clinical, educational and industrial developments. The project will contribute to improve the management of MR with the potential to reduce the high health care costs and to improve quality of life of the concerned population.;3351582,42;2647211;FP7-HEALTH-2007-B;/CP-SICA;ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA;IT;"MOLECULAR STAMPING SRL;UNIWERSYTET MEDYCZNY IM KAROLA MARCINKOWSKIEGO W POZNANIU;TARTU ULIKOOL;NII MEDICINSKOY GENETIKI TOMSKOGO NAUCHNOGO CENTRA SIBIRSKOGO OTDELENIYA ROSSIYSKOY AKADEMII MEDICINSKIH NAUK;INSTYTUT MOLEKULYARNOI BIOLOGII I GENETYKY NAN UKRAINY;THE CYPRUS FOUNDATION FOR MUSCULAR DYSTROPHY RESEARCH;VILNIAUS UNIVERSITETAS;FONDAZIONE EUROPEA PER LA GENETICA;UNIVERZITA KARLOVA;Center of Medical Genetics and Primary Health Care";"IT;PL;EE;RU;UA;CY;LT;CZ;AM";/MED;1;0;0;1;0;0 88979;222992;BRAINCAV;ONG;FP7-HEALTH;HEALTH-2007-1.4-5;FP7;NONHUMAN ADENOVIRUS VECTORS FOR GENE TRANSFER TO THE BRAIN;2008-10-01;2013-03-31;;"Formidable challenges remain to prevent and treat successfully neurodegenerative diseases. Traditional pharmacological approaches, as well as those using stem cells, have made progress but their impact remain limited. As suggested by clinical results in Canavan and Parkinson’s disease, gene transfer offers substantial potential. However, this strategy of therapeutic intervention also brings unique obstacles - in particular the need to address feasibility, efficacy and safety. BrainCAV&apos;s foundation is the potential of canine adenovirus type 2 (CAV-2) vectors, which preferentially transduce neurons and undergo a very efficient long-distance targeting via axonal transport. Moreover, the episomal long-term expression leads to safe, efficient neuron-specific gene delivery. We proposed a structured translational approach that spans basic research through pre-clinical model feasibility, efficacy and safety. To provide a proof-of-principle of the effectiveness of CAV-2, we tackle mucopolysaccharidosis type VII, a global, orphan disease commonly affecting children, and Parkinson&apos;s disease, a focal degeneration of dopaminergic neurones commonly affecting aged population. To develop and execute this project, BrainCAV brings together an interdisciplinary combination of partners with unique expertise that will take CAV-2 vectors to the doorstep of clinical trials.";4325637,23;2984999;FP7-HEALTH-2007-B;/CP-FP;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FR;"CANCER RESEARCH UK;INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE;FUNDACION PARA LA INVESTIGACION MEDICA APLICADA FIMA;UNIVERSITAET LEIPZIG;INSERM - TRANSFERT SA;GENIBET - BIOPHARMACEUTICALS SA;UNIVERSITAT AUTONOMA DE BARCELONA;UNIVERSITY OF GLASGOW;UNIVERSITA DEGLI STUDI DI ROMA LA SAPIENZA;INSTITUTO DE BIOLOGIA EXPERIMENTAL E TECNOLOGICA";"UK;FR;ES;DE;PT;IT";"/MED;/MBI";1;0;0;1;0;0 89498;217180;REMEDIE;ONG;FP7-SSH;SSH-2007-8.0-01;FP7;Regenerative medicine in Europe: emerging needs and challenges in a global context;2008-05-01;2011-04-30;;The globalization of regenerative medicine is gathering pace yet has not been examined with respect to its medium and long term implications for European regulators, the corporate sector or patients located within different member states. Over the coming years it is hypothesised that the global pace of change in this field will be extensive and this needs to be both tracked and assessed for healthcare systems across Europe. But we also argue that it is a field that is characterized by complex dynamics across a range of scientific, clinical and industrial sectors, highly unstable, yet developing rapidly. Building on a platform of research experience, academic and policy networks, and data relevant to the field, this 3 year collaborative project will examine the economic, political and bioethical implications for Europe of near-term and future global developments in the field of regenerative medicine. It will adopt an interdisciplinary approach which brings together social science and humanities researchers to understand the emerging needs, expectations and challenges that Europe faces that is conceptually and methodologically innovative, empirically robust and policy relevant. The objectives of the project are to provide: • A detailed analysis of the competitive position of Europe within the globalisation of regenerative medicine, the requirements of successful innovation in this field and the EU policies that need to be developed to support Europe’s global advantage in the field. • An integrated series of workpackages organised around three inter-related streams of research that constitute the platform for this analysis (the economic, political and bioethical) • An integrated quantitative relational database on the geo-economic pattern of activity within the field of regenerative medicine derived from a) ongoing review of secondary data sources and b) primary data derived from partner projects • The use of novel techniques to interrogate results using geom;1772692;1305878;FP7-SSH-2007-1;/CP-FP;UNIVERSITY OF YORK;UK;"KOZEP-EUROPAI EGYETEM;LIFE SCIENCE GOVERNANCE INSTITUTE;UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA;KING'S COLLEGE LONDON;GOTTFRIED WILHELM LEIBNIZ UNIVERSITAET HANNOVER";"HU;AT;ES;UK;DE";/SOC;1;0;0;1;0;0 104018;300115;iMAPS;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IIF;FP7;The pluton-volcano connection: Integrating processes, volumes and time scales in magma plumbing systems;2012-06-01;2014-05-31;;"Volcanoes frequently affect our lives and thus have been studied since people started living and farming on their nutrient-rich, ash-covered flanks. The processes that cause eruptions also control the compositions and volumes of erupted material and ultimately the eruption styles. These processes and the time scales at which they operate are not well understood. Part of the reason is that many processes controlling eruptions occur in magma reservoirs deep below the volcano. These reservoirs are not easily accessible until they are solidified forming plutons and exposed millions of years later, when volcanic cover rocks are removed through uplift and erosion. The proposed study will, for the first time, integrate research on a fully exposed magma plumbing system in Colorado, USA. Here, volcanic materials are juxtaposed with their plutonic equivalents. The broadly educated applicant, who has carried out field, geochronology and geochemistry studies of plutons in the USA, is teaming up with the host, who has focused his research on volcanic rocks worldwide. The idea is to converge their respective expertise and conduct an interdisciplinary, multilevel analytical study on both volcanic and plutonic rocks. Research will commence with field work, petrographic studies and determination of relative ages. The main element of this study employs novel mineral-scale analyses of crystals from both rock types. The recovery of geochemical information from single crystals, in particular, will be used to provide a record of the processes and timescales operating during magma evolution. The host institution at Durham University has built a state-of-the-art geochemical laboratory for single mineral studies where such detailed crystal scale information recorded during crystal growth can be deciphered. This international study is designed to enhance scientific exchange between the UK and USA, the quality of research and results, and to improve mutual training in the respective fields.";209033,4;209033,4;FP7-PEOPLE-2011-IIF;/MC-IIF;UNIVERSITY OF DURHAM;UK;;;/SCI;1;0;0;1;0;0 89645;213436;NANOTOUGH;ONG;FP7-NMP;NMP-2007-2.1-1;FP7;Nanostructured Toughened Hybrid Nanocomposites for High Performance Applications;2008-10-01;2011-09-30;http://www.nanotough.aau.dk;Motivation: Nanocomposites are emerging new materials that promise improved properties. Their applicability, however, is presently limited by the cost of manufacture and product reproducibility. Literature shows that on the bench scale, dramatic improvement in polyolefin mechanical properties can be obtained by intercalation and exfoliation of nanoparticles in the matrix. However, when materials produced using conventional equipment are tested, their performance does not meet expectations nor live up to the claims (eg. the impact strength too low). Project Goals: To remove technical barriers to producing high performance polymer nanocomposites on the industrial scale, fundamental insight into the dispersion of particles within the matrix is needed. The goal of this project is to gain this insight through a series of carefully designed studies, using the most advanced experimental techniques, theoretical modeling, carried out by very experienced and skilled partners working together in a targeted and interdisciplinary fashion. The basic objective is to obtain a deeper understanding of the interfacial structure of nanocomposites within a polyolefin matrix. This knowledge will enable realization of the great performance potential of these materials through development of novel multiphase and hybrid nanocomposites. This knowledge will facilitate commercialization of polymer nanocomposite materials with superior properties that will lead to development of new products. To meet this objective, we aim to improve the stiffness of polyolefin nanocomposites while not only maintaining but also improving the toughness of the matrix considerably. The technological objective is to optimize and, through novel interface design, to develop new cost efficient hybrid (nanofiller–fiber) nanocomposites as an alternative to heavily filled polymers and expensive engineering polymers and fulfil industry requirements for high performance materials in high tech applications.;7189307;5089000;FP7-NMP-2007-LARGE-1;/CP-IP;AALBORG UNIVERSITET;DK;"LAVIOSA CHIMICA MINERARIA SPA;CENTRO RICERCHE FIAT SCPA;UNIVERSITAET HAMBURG;TEKNOLOGISK INSTITUT;ASSOCIATION POUR LA RECHERCHE ET LE DEVELOPPEMENT DES METHODES ET PROCESSUS INDUSTRIELS;INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU CHIMIE SI PETROCHIMIE ICECHIM;AVIOSPACE SRL;DANMARKS TEKNISKE UNIVERSITET;FPK, SA;UNIVERSITA DEGLI STUDI DI GENOVA";"IT;DE;DK;FR;RO;ES";/NNT;1;0;0;1;0;0 89664;214919;MULTIFLOW;ONG;FP7-PEOPLE;PEOPLE-2007-1-1-ITN;FP7;MULTI-SCALE COMPLEX FLUID FLOWS and INTERFACIAL PHENOMENA;2009-01-01;2012-12-31;;"Understanding and controlling of interfacial phenomena in multiphase fluid dynamics remains one of the main challenges at the crossroad of Mathematics, Physics, Chemistry and Engineering. Examples include film flows, spreading and dewetting of (complex) liquids including suspensions, polymer solutions, liquid crystals, colloids and biofluids. Such systems are central for technological advances in the chemical, pharmaceutical, environmental and food industries and are crucial for the development of Microfluidics and Nanostructuring. The level of detail required by multi-scale flows with interfacial phenomena renders full-scale analyses practically impossible. In fact, such approaches often fail to describe even the results of simple experiments. MULTIFLOW will develop low-dimensional models capable of describing complex interfacial flows coupling different time and length scales. Based on the nature of the dominant mechanism, the scientific program will examine three generic classes: from nano- to macroscale, these are dominated by surface forces, reaction-diffusion, and advection. They are also affected by phase transitions, capillarity, chemical reactions, complex rheology and self-structuring. The strength of the network is its integration of all scientific disciplines, technical skills and expertise necessary to support the multi-scale nature of the envisaged research topics. By fostering the mobility and interdisciplinarity of a strong group of early-stage researchers through a set of well-defined objectives and effective networking between different institutions, disciplines and industries, the ultimate goals of this network are: (i) to create a multi-disciplinary, highly innovative and intersectorial training pool in the field of multi-scale interfacial fluid dynamics; (ii) to generate new tools and techniques for the theoretical-numerical-experimental investigation of such flows, which will be made available to the wider European Community.";6205912;6205912;FP7-PEOPLE-2007-1-1-ITN;/MC-ITN;LOUGHBOROUGH UNIVERSITY;UK;"IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE;ASCOMP GmbH;GEORG-AUGUST-UNIVERSITAT GOTTINGENSTIFTUNG OFFENTLICHEN RECHTS;UNIVERSITE LIBRE DE BRUXELLES;UNIVERSIDAD COMPLUTENSE DE MADRID;TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY;PANEPISTIMIO THESSALIAS;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;Beckman Coulter Biomedical GmbH";"UK;CH;DE;BE;ES;IL;EL;FR";"/EMP;/SOC;/EDU";1;0;0;1;0;0 87853;214566;NANOSCALE;ONG;FP7-NMP;NMP-2007-1.1-1;FP7;Understanding interactions between cells and nanopatterned surfaces;2008-07-01;2011-06-30;http://www.nanoscale-fp7.eu/;"The study of biological processes occurring at the nanoscale is becoming a new discipline at the border between Physics and Biology with major scientific challenges and new technological applications. In fact, interactions at the nanoscale between cells/neurons and surfaces with specific nanopatterns appear to control several major biological processes, such as cell proliferation and differentiation. The aim of the present NanoScale proposal is therefore to explore interactions between stem cells, neurons, neuronal networks and surfaces with specific geometrical nanopatterns and nanoprints of specific proteins and molecules. In order to do so, we have formed an interdisciplinary consortium consisting of five major European research centres (SISSA, TASC-INFM, DTU, NMI and ENS) with two SMEs (MCS, Promoscience) gathering biological knowledge and expertise in the fabrication of nanostructures and of their manipulation. The NanoScale proposal will produce and develop a variety of nanodevices for growing, guiding, manipulating cells, neurons and neuronal cultures. It is composed of two major ingredients: i - the combination of a MicroElectrode Arrays (MEAs) with chemical and topographic micro/nanosubstrates controlling the network growth; ii – the coupling with external measuring and/or manipulating devices such as Electron Microscopes and Optical Tweezers. We expect to provide an answer to new scientific issues and therefore achieving major scientific breakthroughs. In addition, our proposal will produce new knowledge and know-how enabling the development of new marketable products that will be commercialised by MCS.";3960781;3030405;FP7-NMP-2007-SMALL-1;/CP-FP;SCUOLA INTERNAZIONALE SUPERIORE DI STUDI AVANZATI DI TRIESTE;IT;"MULTI CHANNEL SYSTEMS MCS GMBH;Naturwissenschaftliches und Medizinisches Institut an der Universität Tübingen;ECOLE NORMALE SUPERIEURE;CONSIGLIO NAZIONALE DELLE RICERCHE;DANMARKS TEKNISKE UNIVERSITET;Promoscience srl;Glance Vision Technologies s.r.l.";"DE;FR;IT;DK";"/BIO;/NNT";1;0;0;1;0;0 86654;221538;INTELSENS;ONG;FP7-PEOPLE;PEOPLE-2007-2-1.IEF;FP7;Integrated Laser Sensor for Exhaled Anaesthetic Agent Monitoring;2008-06-01;2010-05-31;;The application of a novel ultra-sensitive photoacoustic gas sensor is proposed to allow for online monitoring of an intravenously administered anaesthetic agent, which is exhaled at trace levels with the patient’s breath during surgery. We respond to a real and acute need for clinical online monitoring of anaesthetic concentrations in the patient’s blood stream during surgery. In the drafting of this proposal, the Applicant, himself from a physical sciences background, has extensively consulted with Prof. T. Absalom and Dr. D Wheeler, Division of Anaesthesia, School of Clinical Medicine, University of Cambridge, UK to define the clinical problem at the core of this application. The project focuses on the monitoring of propofol, one of the most widely used intravenous anaesthetics in general anaesthesia. Currently the effectiveness of propofol induced anaesthesia is only assessed symptomatically, based on highly subjective and unsophisticated scoring. A viable online capability to monitor exhaled trace levels of propofol in patients does not currently exist but would dramatically improve the level of control over its administration. It would both improve the quality of anaesthetic management by tailoring dosage to the individuals’ needs, reduce clinical recovery times and patient aftercare with associated cost benefits. The project is based on a unique interdisciplinary ensemble of physicists, chemical engineers, medical professionals and potential commercial manufacturers focusing on a high impact engineering challenge. The Applicant has an excellent academic background. He has already gained international recognition in terms of invited conference contributions. He has been one of the key players to develop the proposed sensor technology. The proposed high impact project in a multidisciplinary environment at the University of Cambridge, UK, would fully qualify the Applicant for an independent research post at an internationally recognised research institution.;178874,06;178874,06;FP7-PEOPLE-2007-2-1-IEF;/MC-IEF;THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;UK;;;"/SCI;/EDU";1;0;0;1;0;0 87817;211820;GMSAFOOD;ONG;FP7-KBBE;KBBE-2007-2-5-01;FP7;Biomarkers for post market monitoring of short and long-term effects of genetically modified organisms (GMOs) on animal and human health;2008-08-01;2012-03-31;http://www.gmsafoodproject.eu;The function of post market monitoring is to further assess possible nutritional and health effects of authorized GM foods on a mixed population of human and animal consumers. Currently, however, little is known about exposure levels, whether adverse effects are predictable, and the occurrence of any unexpected effects following market release of GM foods. Our objective is to identify a panel of anatomic, physiologic, biochemical, molecular, allergenic, and immunogenic biomarkers, which could be used to predict harmful GMO effects after product authorization. Using a prototype allergenic ?-amylase inhibitor GM-pea, we will extrapolate multiple biomarker databases that correlate GMO effects during gestation, growth, maturation in various animal models with humans. We will establish biomarkers in GMO-fed pigs, salmon, rats, and mice, in addition to indirect effects of GM feeding in the food chain and GMO influence during an underlying allergic disorder. These experiments will yield data on general health with a specific focus on allergy and immunology. To extrapolate our data to humans, we will establish a comparative database with antigenic epitopes and antibody crossreactivity in legume allergic patients and human-mouse chimera in which a human immune system is transplanted into a mouse lacking an immune system. Taken together, these results will yield databases from multiple biological systems that will be used in a mathematical modeling strategy for biomarker discovery and validation. Our consortium consists of partners from Austria, Turkey, Hungary, Ireland, Norway, and Australia and constitutes a diverse interdisciplinary team from veterinary medicine, nutrition, agriculture, immunology, and medicine that is dedicated to the development and validation of biomarkers to be used for post market monitoring of animals and humans consuming newly authorized GMOs.;3424810,58;2606622;FP7-KBBE-2007-1;/CP-FP;MEDIZINISCHE UNIVERSITAET WIEN;AT;"KOZPONTI ELELMISZER-TUDOMANYI KUTATOINTEZET;NORGES VETERNINAERHOGSKOLE;NEMZETI AGRARKUTATASI ES INNOVACIOSKOZPONT;NORGES MILJO-OG BIOVITENSKAPLIGE UNIVERSITET;TROYKA MAKINA GIDA INSAAT MUHENDISLIK ENERJI CEVRE BILISIM ARASTIRMA GELISTIRME DANISMANLIK SANAYI VE PAZARLAMA LIMITED SIRKETI;COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION;TEAGASC - AGRICULTURE AND FOOD DEVELOPMENT AUTHORITY";"HU;NO;TR;AU;IE";"/LIF;/VAS";1;0;0;1;0;0 88613;217488;JAD-PBP;ONG;FP7-SSH;"SSH-2007-4.2-02;SSH-2007-4.2-01";FP7;Just and durable peace by piece;2008-02-01;2011-01-31;;Peace is elusive and the quest for peace is perpetual. In Iraq, Afghanistan and the Middle East, peace and war exist in parallel and contemporary peace support operations simultaneously involve combat operations and building peace. Hence, the goal of establishing just and durable peace is a fundamental challenge to contemporary peacemakers and academics alike. In order to shed new theoretical and conceptual light on the problematique of building just and durable peace and to offer policy-relevant advice, the team JAD-PbP has identified three critical challenges, which constitute the core of the proposal. The first challenge focuses on the quest for justice in contemporary peace processes, which has become increasingly apparent as several violent conflicts and wars are distinguished by gross human rights violation and ethnic cleansing. The second challenge concerns the quest for durable peace. Several contemporary conflicts tend to resist negotiated settlement. Yet, the ones that do reach a peace agreement still have a poor track record on implementation. The third challenge relates to the quest for effective strategies, particularly concerning the involvement of international actors in peacebuilding. JAD-PbP is convinced that the only way to address these challenges is through an interdisciplinary approach, drawing on insights in peace and conflict research, international law, political science and international relations. JAD-PbP has four core scientific objectives: (1) Enhance theoretical and methodological conceptualisation of just and durable peace (2) Analyse legal and democratic accountability of peacebuilding strategies, including mapping international law and norms on the use of force for humanitarian reasons. (3) Examine the effectiveness of general peacebuilding strategies and evaluate to what extent they enhance just and durable peace (4) Examine and compare EU:s peacebuilding strategies in Western Balkans and the Middle East;1761312;1349934;FP7-SSH-2007-1;/CP-FP;LUNDS UNIVERSITET;SE;"Regional Centre on Conflict Prevention;UNIVERSITY OF BATH;UPPSALA UNIVERSITET;THE UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS;UNIVERSITY OF EAST LONDON;THE HEBREW UNIVERSITY OF JERUSALEM";"JO;UK;SE;IL";"/SOC;/LEG;/POL";1;0;0;1;0;0 95700;256354;REKSARD;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-RG;FP7;Receptor-like Kinase Signalling in Arabidopsis thaliana Root Development;2011-06-25;2014-06-24;;"The past decade researchers have mainly focused on the analyses of phytohormone gradients and mobile transcription factors to explain patterning. In Arabidopsis, model processes like primary and lateral root development are well understood on the level of transcriptional changes and hormonal control, but very little attention has been given to an alternative way of cell-cell communication using ligand-receptor-like kinase systems (De Smet et al., 2009, Nat Cell Biol, in press). Lately a number of receptor-like kinases and potential ligands have been described in root development (De Smet et al., 2008, Science 322:494-497; Müller et al., 2008, Plant Cell 20:934-946; Stahl et al., 2009, Curr Biol 19:909-14), making it a perfect time to start investigating how these receptor-like kinases and their respective ligands control the different developmental processes and what their targets are. More and more tools become available to study difficult membrane proteins on the level of 3D structure, phosphoproteomics, and in silico ligand identification. In brief, I will use different and interdisciplinary strategies, based on state of the art transcriptomics, proteomics, interactomics, associomics and more in depth analysis on the single gene/protein/ligand level to describe ligand-receptor-mediated cell-cell communication during root development, and, more specifically, to identify key components in ACR4-dependent signalling. The aspects this project plans to address would contribute extensively to the knowledge of membrane associated receptors-like kinases in general, have rarely been covered focusing on one receptor-like kinase, and will allow elucidating the mechanisms and structural aspects behind this crucial ACF4-dependent signaling pathway, such as: (1) identification of downstream genome-wide transcriptional changes, (2) identification of substrates on a proteome-wide scale, and (3) identification and physical interaction of ligands with the receptor domain.";45000;45000;FP7-PEOPLE-2009-RG;/MC-ERG;THE UNIVERSITY OF NOTTINGHAM;UK;VIB;BE;/SCI;1;0;0;1;0;0 90726;234782;3DZZI;ONG;FP7-PEOPLE;FP7-PEOPLE-IEF-2008;FP7;Three-dimensional structure of stratified turbulence;2009-06-01;2010-10-31;;A new flow instability, known as zig-zag instability, has been revealed to be at the origin of the spontaneous formation of decoupled horizontal layers in stably stratified fluids (density decreasing along the vertical). Such layered structure is widely observed in the atmosphere and oceans. It governs the vertical transport of pollutants and chemical components and the dissipation of momentum. A critical problem is, for example, the thermal inversion in urban areas that causes the stagnation of pollutants and small particles in the lower part of the atmosphere. The main goal of this research is to investigate the linear and nonlinear evolution of the zig-zag instability in complex stratified flows as previous work has been restricted to prototype flows. This will improve the fundamental understanding of stratified turbulence, a crucial step towards developing accurate parametrization of stratified turbulence in numerical models of the atmosphere and oceans. The research will be carried out through theoretical and numerical studies and with new designed laboratory experiments and measurement techniques which may result in the development of patents with the collaboration of the European industry. This project provides the opportunity to work on a highly interdisciplinary topic at an internationally renowned institution, the Laboratoire d'Hydrodynamique at Ecole Polytechnique, offering the possibility to translate research results into academic papers and patents, which can be used in both academic and practitioner contexts. Understanding the dynamics of stratified turbulence will be valuable to improve climate models and to support future predictions in forthcoming Intergovernmental Panel of Climate Change reports.;165444,54;165444,54;FP7-PEOPLE-IEF-2008;/MC-IEF;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FR;;;"/SCI;/EMP";1;0;0;1;0;0 90764;229600;COFUND-CERN;ONG;FP7-PEOPLE;PEOPLE-2007-2-3.COFUND;FP7;Cofunding of the CERN Fellowship Programme;2009-04-01;2013-03-31;;For many years, CERN has operated a trans-national Fellowship programme, offering scientists and engineers challenging opportunities in particle physics research, and in related fields of physics and technology. The COFUND action offers CERN a timely opportunity to enhance the mobility element of this programme, which is open to nationals of all countries. This opportunity comes at a time when the startup of the Large Hadron Collider makes CERN one of the most exciting places to work for the global physics and technology community. Mobility will be enhanced through the opportunity to spend up to one third of the Fellowship in external institutions, including industrial laboratories. The employment conditions will be improved by offering three-year appointments rather than the standard two-year terms of CERN Fellows. These improvements, enabled by the COFUND action, will further increase the competitiveness of CERN’s Fellowship Programme. In particular, they are expected to trigger a strong reintegration effect on European researchers presently based in the US. Applicants will propose their own research projects. Selection will be based on the scientific potential of the proposal, and on the demonstrated excellence of the candidate. Working on frontier research and technology projects and profiting from the unique facilities available at CERN, the co-funded Fellows will deepen their knowledge in their own field and acquire international visibility and reputation. They will broaden their skills using the numerous training opportunities and through their exposure to an interdisciplinary and multi-national environment. Inter-sectorial skills will be fostered through CERN’s industrial collaborations and technology transfer projects. Fellows will spend at least two thirds of their Fellowship at CERN. We consider this provision to be justified by the size of CERN, the diversity of the research and training opportunities, and by the uniqueness of CERN’s facilities.;;4996414;FP7-PEOPLE-2007-2-3-COFUND;/MC-COFUND;EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH;CH;;;"/REG;/SCI";1;0;0;1;0;0 91926;237365;SPIM;ONG;FP7-PEOPLE;FP7-PEOPLE-IIF-2008;FP7;Metallopolymers with Metal-Metal Bonds: The Synthesis, Characterization and Applications of Novel Molecular Wires;2009-09-01;2011-08-31;;In this project the synthesis of metal-metal bonded oligomeric or polymeric linear metal chain complexes from metal-metal bonded dimetallic units by various methods is proposed. Nanoscience applications of the newly synthesized materials, e.g. as molecular wires, will be investigated. The proposed research on Metallopolymers with Metal-Metal Bonds: The Synthesis, Characterization and Applications of Novel Molecular Wires is at the cutting edge of the advanced functional polymer field and is both highly interdisciplinary and multidisciplinary. The project involves synthetic inorganic and coordination chemistry, synthetic polymer chemistry and polymer materials science and nanoscience. The project described herein would thus have a substantial multidisciplinary impact that reaches beyond purely the chemical sciences into materials science and physics.;181350,76;181350,76;FP7-PEOPLE-IIF-2008;/MC-IIF;UNIVERSITY OF BRISTOL;UK;;;"/SCI;/EMP";1;0;0;1;0;0 86440;209938;TAMBO;ONG;FP7-PEOPLE;PEOPLE-2007-4-3.IRG;FP7;Societies of South Peru in the Context of Climatic and Environmental Change, Late Pleistocene to Modern Age – Rio Tambo Projekt;2008-04-01;2012-03-31;;"The project, Societies of South Peru in the Context of Climatic and Environmental Change, Late Pleistocene to Modern Age (Rio Tambo Project), is intended – basing on research made in the valley of Rio Tambo and the adjacent coastal zone– to present an analysis of climatic and environmental change at work in the region of S. Peru starting from late Pleistocene until present and the impact of these changes on the character of human settlement. Apart from tracing the process of adaptation of human groups inhabiting the region to gradual global shifts of climate and vegetation the project is expected to help in determining the impact of on smaller scale seasonal shifts in climate (short-lived from the perspective of climatology), only regional or local in impact. The main source of climatic impact on a regional scale has been El Ni?o which influenced processes of settling and withdrawal of human settlement in specific areas of the valley and the ocean coast. Local-scale impact (limited in range) is primarily associated with seismic and volcanic phenomena which are noted with special intensity in the southernmost part of Peru, ie, in the region of the proposed research. The proposed research is interdisciplinary in character and envisions close cooperation of a wide range of specialists from the fields of climatology, palaeogeography and volcanology, as well as archaeologists, ethnologists and specialists from other fields, eg photogrammetry, C14 analysis and palaeobotany. The project will document from a chronological perspective climatic and environmental change in the study area, defining their parameters and reconstructing the stages of colonisation by human settlement and its decline in individual ecological enclaves; a phenomenon which is observed in Andean valley areas also in modern times.";100000;100000;FP7-PEOPLE-2007-4-3-IRG;/MC-IRG;UNIWERSYTET WROCLAWSKI;PL;;;"/SCI;/COO";1;0;0;1;0;0 95038;256544;ND-ETCRYPTOUC;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-RG;FP7;New Directions in Efficient and Tamper-Resilient Public-Key Cryptography for Ubiquitous Computing;2010-07-01;2014-06-30;;"Emerging ubiquitous devices such as WSN nodes and RFID tags, which have extremely limited resources, require complex cryptographic algorithms for security & privacy. While widely used cryptographic algorithms are known to be strong against computational resources of an attacker, the real threat comes from fault and side-channel attacks which try to extract the cryptographic key by utilizing the flaws in the implementation of an algorithm rather than the algorithm itself, e.g. side-channel attacks exploit information such as timing, power dissipation or electromagnetic emanation. This threat becomes more significant for WSN nodes, or RFID tags, with limited cryptographic capabilities and air as the easily tappable communication medium. Hence, it is crucial that cryptographic algorithms for these devices are implemented targeting side-channel resistance and tamper-resilience as well as performance. This project has three main objectives: 1) Investigation of efficient frequency domain arithmetic algorithms for standard cryptographic schemes; 2) Investigation of the feasibility of area/power-efficient realization of these algorithms for constrained ubiquitous devices through proof-of-concept implementations; 3) Investigation of the potential inherent tamper-resilience and side-chanel resistance of frequency domain arithmetic for robust cryptographic implementations. This timely and interdisciplinary project will draw knowledge from diverse fields such as hardware engineering and applied mathematics to provide security to emerging ubiquitous devices. It will also help with the successful reintegration of Dr. Baktir into the European Research Area and give him the necessary resources to establish his research in Europe. Furthermore, it will significantly help transfer of knowledge to the host through cutting edge research, lasting co-operation with the third country and training of young researchers, and thus contribute to the European excellence in research.";100000;100000;FP7-PEOPLE-2009-RG;/MC-IRG;BAHCESEHIR UNIVERSITESI FOUNDATION;TR;TURKIYE BILIMSEL VE TEKNOLOJIK ARASTIRMA KURUMU;TR;/SCI;1;0;0;1;0;0 88869;223736;TRANSMALARIABLOC;ONG;FP7-HEALTH;HEALTH-2007-2.3.2-9;FP7;Malaria Transmission Blocking by Vaccines, Drugs and Immune Mosquitoes: Efficacy Assessment and Targets;2008-12-01;2013-05-31;;"Malaria is a complex disease, dependent on multiple host/parasite/vector interactions. This tripartite system offers numerous opportunities for disease-preventing interventions, but also creates robustness that undercuts ‘magic bullet’ expectations. Our interdisciplinary TransMalariaBloc will approach the challenge of malaria control in the field from this perspective. It utilizes the enormous recent advances in our molecular understanding of the three implicated organisms without prejudicing which targets or process will prove most suitable to transmission blocking (TB). In a feedback loop of experimentation and modeling, we will address the potential and actual impact of TB drugs and remedies which supplied to human hosts, can block transmission from an infected bloodmeal; TB vaccines which elicit human antibodies to antigens essential for transmission; and immune mosquitoes, genetically modified (GM) to achieve natural or synthetic refractoriness. Recent studies suggest that vector/parasite genotypic interactions determine the success or failure of Plasmodium falciparum to infect mosquitoes. In this perspective, we will assay genome-wide polymorphisms in both parasites and vectors to dissect important genotype*genotype interactions, thus guiding the development of effective TB vaccines, drugs and remedies, and GM mosquitoes. Effectiveness of TB interventions, especially via use of GM mosquitoes, depends on the balance of infection and resistance costs. Components of this balance will be explored, to foresee the dynamics of vectorial competence in mosquito populations and assess the efficacy of TB strategies, as well as guide the development of new targets. Again, interaction between modeling and experimentation will be a powerful combination. This proposal represents an ambitious, but feasible approach, spanning from molecular to population and environmental levels, to optimizing TB interventions for malaria control in endemic areas.";3973193,4;2993964;FP7-HEALTH-2007-B;/CP-FP;IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE;UK;"LIVERPOOL SCHOOL OF TROPICAL MEDICINE;UNIVERSITA DEGLI STUDI DI CAMERINO;FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS;MAKERERE UNIVERSITY;CENTRE NATIONAL DE RECHERCHE SCIENTIFIQUE ET TECHNOLOGIQUE*INSTITUT DE RECHERCHE EN SCIENCES DE LA SANTE;INSTITUT DE RECHERCHE POUR LE DEVELOPPEMENT";"UK;IT;EL;UG;BF;FR";/MED;1;0;0;1;0;0 93284;236283;SCIENCE ON TV;ONG;FP7-PEOPLE;FP7-PEOPLE-IOF-2008;FP7;Identifying best practices for successful facilitation of science learning through general interest television programming;2010-02-01;2012-01-31;;"Science communication is an almost non-existing field in the Israeli Academia and I see as my professional goal to spearhead its development. Therefore, the research proposed is aimed at identifying best practices for successful facilitation of science learning through general interest television programming, in order to increase the general publics' science literacy. This research proposal has a strong interdisciplinary aspect: it is situated at the crossroad of science education (specifically in free choice settings) and science communication (specifically science journalism). It is planned to enable me to take advantage of my existing skills, and at the same time gain knowledge of new research methodologies. So far, my research and training has been in the field of Science Education. This discipline does share similarities with the field of science communication, such as theoretical background and research methodologies in the area of informal science education. However, notwithstanding those similarities and my personal background as a science communicator (reporter, editor and TV presenter) it is clear to me that to meet my professional goals I need the superb formal science communication training that is available in Cornell under the guidance Prof. Lewenstein. As a junior faculty member it is important for me to develop my own niche in the academic environment and in order to further my academic position I am required by my University to complete a Post Doc in another country.";153377,42;153377,42;FP7-PEOPLE-IOF-2008;/MC-IOF;TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY;IL;;;"/COO;/EDU";1;0;0;1;0;0 92250;235482;SUPERANTIBODIES;ONG;FP7-PEOPLE;FP7-PEOPLE-IEF-2008;FP7;Synthetic Superantibodies – Bioinspired Engineering of Artificial Receptor Structures;2009-05-01;2011-04-30;;The project “Superantibodies” encompasses an interdisciplinary approach to accomplish the first instance of a biohybrid, yet fully synthetic three dimensional recognition element by converging the benefits of natural biorecognition with those of a synthetic approach. The bio-inspired concept is modelled on the antibody binding site whose binding capacity is the result of a defined three-dimensional structure in which loops of polypeptides cooperatively interact with the antigen through specific biomolecular interactions. The project implements a combination of modern biomolecular and bioanalytical techniques to identify peptides within these structures that are pivotal for the interaction with the antigen, and to use organic chemistry to synthetically mimic these peptides whilst maintaining their biological function. Affinity driven self-assembly between these peptides and their specific antigen is used to produce templates for a subsequent molecular imprinting process, resulting in a site-specific integration of peptides into the structural backbone of a molecularly imprinted polymer. It is hypothesised that it will be possible to rationally engineer recognition elements with tailored affinities by changing the number and the type of the embedded peptides to rationally create structures whose affinity can outperform that of naturally derived antibodies. This proposal is built on the expertises and scientific strengths of Dr Heiko Andresen while taking him in new directions. The multidisciplinary group of Dr Molly Stevens provides a fertile environment for the scientific and professional development of the applicant, and Imperial’s infrastructures and dedication to high-quality professional and personal career development strongly support Dr Andresen in reaching a position of professional maturity. The project proposal is in line with aims and policy objectives of the FP7, with particular high relevance for the theme-crossing FP7 initiative ‘NanoMedicine’.;;171300,62;FP7-PEOPLE-IEF-2008;/MC-IEF;IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE;UK;;;"/SCI;/EMP";1;0;0;1;0;0 92139;236567;DNA AND SOCIETY;ONG;FP7-PEOPLE;FP7-PEOPLE-IEF-2008;FP7;Science and Society: From a History of the “Emotional Images of DNA” to a Set of Multidisciplinary Actions for Disseminating Good Social Values in Europe;2009-10-01;2011-09-30;;"Joining Life Long Learning, Sociology of Science, contemporary Genetics, and the recommendations of the Science and Society European Action Plan published by the EU in 2002, this proposed project revolves around society’s image of DNA. Society has many ideas regarding the genetic code: DNA as guarantor of social positions; DNA as a mold from which cloning is possible; DNA as repository of human qualities, etc. Comparing those ideas with the recent advancements in the life sciences we find sometimes a gap between science and society’s convictions that can hinder the scientific progress and intercultural integration of Europe. The theoretical objectives of the proposal aim to outline an history of DNA ideas present in society through an analysis of cultural elements (scientific knowledge, emotions, evocations, etc.) and of channels (theater, literature, divulgation, etc.) that contribute to their formation and diffusion. The practical actions give rise to a permanent interdisciplinary workshop, aimed at creating “cultural objects” that use narrative languages to spread a realistic and positive idea of the relationship DNA/CULTURE. This experience will allow the applicant to advance in his career becoming the coordinator of the workshop and earn the professorship on themes discussed in this proposal at the Universit? di Catania (Italy).";165444,54;165444,54;FP7-PEOPLE-IEF-2008;/MC-IEF;ECOLE DES HAUTES ETUDES EN SCIENCES SOCIALES;FR;;;"/SCI;/EMP";1;0;0;1;0;0 91491;221813;LEGAL DISCURSIVITY;ONG;FP7-PEOPLE;PEOPLE-2007-2-1.IEF;FP7;DISCURSIVITY. A PHILOSOPHICAL INQUIRY INTO LEGAL THEORY;2008-09-01;2010-08-31;;The notion of legal discourse is used in many studies as a tool or a frame meant to understand various European legal issues. Yet, the fragmentation and multiplicity of the researches (semiotics, philosophy of language, linguistics, and legal theory) hinders a more comprehensive approach to the subject. Indeed, the logic of legal discourse raises problems that have been addressed so far only in a superficial and piecemeal manner, either by philosophy of law or legal theory. There lacks a systematic and pluridisciplinary study of legal language, capable of integrating all the different relevant remarks into a more general frame. This project is aimed precisely at giving a new, rigorous definition of legal discursivity. Its ambition and originality is to integrate various disciplines and authors of different national traditions in an interdisciplinary approach, in which philosophy plays a key role. Bringing together contemporary semiotics, linguistics and legal theory into a philosophical perspective, this research intends to help constitute a new frame of reflection for legal language and rationality. By excavating its philosophical basis, and unveiling its legal particularities, this investigation bestows the vague notion of legal discourse with the precise and operational dimension of a true concept. Such inquiry will in fact give an illuminating insight into most of the relevant logical remarks pervading contemporary legal theory. This research shall particularly focus on Ricoeur and Habermas’ works, whose disagreements have not been systematically explored by the literature so far. Since their respective reflections on justice and legal theory are logically related to a very consistent philosophy of language, confronting their work is indeed the best way to understand the current difficulties in discourse theory identified by contemporary legal philosophy.;164886,6;164886,6;FP7-PEOPLE-2007-2-1-IEF;/MC-IEF;UNIVERSITE LIBRE DE BRUXELLES;BE;;;"/SCI;/EDU";1;0;0;1;0;0 90586;236493;ELSAIDTCGT;ONG;FP7-PEOPLE;FP7-PEOPLE-IIF-2008;FP7;Ethical, Legal, and Social Aspects and Implications of Direct-to-Consumer Genetic Testing;2009-05-22;2011-05-21;;"With ongoing genetic discoveries and improvements in technology, more genetic tests are made available in a clinical context than ever before. Along with the increase in genetic tests offered there has been a recent rise in companies providing various genetic tests directly-to-consumers (DTC) bypassing the traditional face-to-face meeting with a health care professional. DTC genetic tests have generated various concerns with regard to tests’ analytical and clinical validity, as well as clinical utility; issues related to the quality of pre- and post-test counselling; and the lack of legal regulation. The overall objectives of this research project are to investigate the ethical, legal and social aspects and implications of the provision of genetic tests directly to consumers as is currently done by various companies. Five specific goals form the basis of this work: Firstly, a systematic and indepth review of the field of DTC companies will be performed using content analysis of company web sites. Secondly, this project aims to compare the existing regulatory framework of DTC genetic testing in Europe and North-America (US and Canada). Thirdly, the attitudes of European and North-American geneticists regarding the provision of direct-to-consumer genetic services will be surveyed and analyzed. Fourthly, as a case study of such services, companies offering tests for psychiatric diseases as well as the potential consequences of such services will be investigated. Finally, the last goal will be to disseminate the knowledge developed and to stimulate international and interdisciplinary collaboration by developing a website and organizing an international workshop, network, and conference. Dr. Heidi Howard, (Ph.D. Genetics 2003, MA Bioethics 2008) will, by her background in genetics and ethics, provide a complimentary approach to the multidisciplinary character of the Centre for Biomedical Ethics and Law (K.U.Leuven).";;220226,8;FP7-PEOPLE-IIF-2008;/MC-IIF;KATHOLIEKE UNIVERSITEIT LEUVEN;BE;;;"/SCI;/EMP";1;0;0;1;0;0 90423;236467;SYMBIS;CAN;FP7-PEOPLE;FP7-PEOPLE-IEF-2008;FP7;SYMBionts in Insect Societies: reproductive manipulation and the fitness effects of Wolbachia in leaf-cutting ants;2009-03-01;2010-03-31;;Social insects include some of the most ecologically dominant species in both temperate and tropical areas, and represent a major evolutionary transition in the development of complexity. Insect societies are consequently of considerable interest for biologists and the general public. One emergent field of special interest is the interaction between social insects and their parasites both because of the role these are likely to have played in the evolution of sociality in insects and the parallels with the challenges presented to our own societies by disease. However, most studies of social insect parasites have been limited to those that cause obvious symptoms of infection, whereas many are more cryptic. These include the ubiquitous bacterial parasite Wolbachia which has been the subject of an explosion of research in non-social insects in recent years. This project will use leaf-cutting ants as a model system to examine for the first time experimentally the fitness effects of Wolbachia infections in social insects. It will involve interdisciplinary collaboration and advanced training in key scientific skills (ecology and population genetics) that my molecular genetic PhD did not include. The fellowship will greatly enhance my potential for achieving a position of professional maturity and independence as a broadly trained biologist.;181350,76;181350,76;FP7-PEOPLE-IEF-2008;/MC-IEF;UNIVERSITY OF LEEDS;UK;;;"/SCI;/EMP";1;0;0;1;0;0 90492;237765;SIM-ON;ONG;FP7-PEOPLE;FP7-PEOPLE-IEF-2008;FP7;Single Cell Imaging of Gene Activation during Oxidative Neuron Death: Towards Quantitative Systems Approaches;2009-05-01;2011-04-30;;"Ischaemic stroke and neurodegenerative disorders are leading causes of death and disability and their incidence is rising rapidly due to increases in European life expectancy. Excessive apoptosis is pathogenic when it concerns post-mitotic cells such as neurons; for instance in stroke or neurodegenerative diseases. Oxidative stress is a major contributor to ischemic and neurodegenerative processes; however, the molecular mechanisms and biological switches that determine outcome, i.e. neuronal tolerance or neuronal apoptosis, in response to oxidative stress are not fully characterised. This aim of this project is to analyse these events at the single cell level. The applicant has an excellent track record in the molecular analysis of pro-apoptotic gene activation in response to oxidative stress. Here, we propose to monitor and quantify the activation of cytoprotective (ARE- and HSE-containing) vs. pro-apoptotic (BIM) gene expression in neurons and astrocytes in real-time using GFP-based reporter assays and employing quantitative confocal and epifluorescence microscopy approaches. The quantitative single-cell data obtained will be incorporated into mathematical models of apoptosis activation developed by the host laboratory. The suggested fellowship will advance our understanding of this critically important biological process by allowing for a quantitative analysis of this signalling/gene activation network. The fellow will strongly complement the research activities of the host laboratory, and most importantly, will acquire new skills and be exposed to a unique interdisciplinary training programme. Furthermore, this work could provide important information for the development of new therapeutic strategies for ischemic and neurodegenerative disorders.";;177354,02;FP7-PEOPLE-IEF-2008;/MC-IEF;ROYAL COLLEGE OF SURGEONS IN IRELAND;IE;;;"/SCI;/EMP";1;0;0;1;0;0 88415;213143;SARNISSA;ONG;FP7-KBBE;KBBE-2007-1-2-12;FP7;Sustainable Aquaculture Research Networks in Sub Saharan Africa;2008-02-01;2011-04-30;;"The project concept is to build a sustainable aquaculture research network based on academics and other professionals between Europe and Africa, with a focus on Sub-Saharan Africa. The three-year work plan will strengthen alliances among experienced and emergent players in the African and wider aquaculture scene that will build on an existing framework knowledge resource base and exchange platform - the ‘Aquaculture Compendium’. Project partners: Institute of Aquaculture, University of Stirling (coordinator; UK); CIRAD (France); WorldFish Center (Egypt), CABI (UK HQ); Asian Institute of Technology (Thailand), Bunda College of Agriculture (Malawi); IRAD (Cameroon); and ETC (Netherlands). This consortium has a balance of expertise in aquaculture research, development and policy information technology; ability to work in different linguistic areas; and a track record in the implementation of activities at local to international levels. The project will work across a wide range of stakeholders (researchers, SMEs, government agencies, NGOs, producers and others) throughout Sub-Saharan Africa; between anglophone and francophone regions in Africa; between Africa and Asia; and between Europe and Africa. In 6 Work Packages, the project will deliver (1) the comprehensive interdisciplinary knowledge base required for Sub-Saharan African aquaculture to develop in a sustainable way; (2) a sustainable process to identify and nurture new initiatives for Sub-Saharan African aquaculture research, with key involvement of European stakeholders; (3) learning and adaptation for Sub-Saharan Africa of the processes of aquaculture research–into-practice through multi-stakeholder collaboration of research-to-practice networks developed in Southeast Asia; (4) maximal dissemination of project outputs; and (5) tools to aid policy-making for aquaculture in Africa. Mechanisms will be in place by the project end to enable sustainability of the networks established during the project.";1216824,4;996036;FP7-KBBE-2007-1;/CSA-CA;THE UNIVERSITY OF STIRLING;UK;"STICHTING ETC;UNIVERSITY OF MALAWI;ASIAN INSTITUTE OF TECHNOLOGY;CENTRE DE COOPERATION INTERNATIONALE EN RECHERCHE AGRONOMIQUE POUR LEDEVELOPPEMENT - C.I.R.A.D. EPIC;INSTITUT DE RECHERCHE AGRICOLE POUR LE DEVELOPPEMENT;INTERNATIONAL CENTER FOR LIVING AQUATIC RESOURCES;CAB INTERNATIONAL";"NL;MW;TH;FR;CM;MY;UK";"/SEA;/REG;/COO";1;0;0;1;0;0 109652;607080;VITRIMETTECH;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-ITN;FP7;Vitrified Metals Technologies and Applications in Devices and Chemistry;2013-10-01;2018-01-31;;"VitriMetTech aims at educating a group of young researchers to implement methods for cutting edge research on new metallic glasses (e.g. Fe, Mg, Al, Ti-based), also in bulk form, and their amorphous/crystalline composites, for functional, bio-mechanical, chemical and structural micro-part applications. Transfer of results to industrial companies will boost innovation in a part of the Metal sector of the European manufacturing industry. This interdisciplinary proposal by ten of the best European academic research teams with six private sector companies will both improve the availability of materials and technologies in fields were metallic glasses are already in the production line (e. g. magnetic devices), and open up new fields of application in chemistry (e. g. in catalysis and spectroscopy) and electrical and electronic engineering (e. g. motor components and MEMS). VitriMetTech comprises five Research Projects which are designed to achieve the following objectives: 1) Soft magnets with low or zero-magnetostriction for use in inductors and toroid-shaped or flat transformers. 2) Highly magnetostrictive alloys to exploit magneto-mechanical coupling for energy harvesting and cantilever devices. 3) Bio-corrodable Mg-based bulk vitrified metals for implants free of toxic elements and with low elastic modulus. 4) Nano-porous metals made from metallic glass precursors for electro- and heterogeneous catalysis, enhanced Raman spectroscopy, flexible electrodes and actuators. 5) Improving the mechanical properties of vitrified metals for the above applications: suppression of shear banding and attain ductility as a function of sample size, composition, and temperature. The training programme overcomes barriers among traditional disciplines providing top level tuition to 16 fellows (10 ESRs and 6 ERs) on topics spanning from laboratory work for the synthesis and property characterization, to processing and device fabrication, and on a full set of complementary skills.";3465780,12;3465780,12;FP7-PEOPLE-2013-ITN;/MC-ITN;UNIVERSITA DEGLI STUDI DI TORINO;IT;"METALLGIESSEREI BREUCKMANN GMBH & CO KG;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;INSTITUT POLYTECHNIQUE DE GRENOBLE;UNIVERSITAET ULM;EUROPEAN SYNCHROTRON RADIATION FACILITY;GEORG-AUGUST-UNIVERSITAT GOTTINGENSTIFTUNG OFFENTLICHEN RECHTS;INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE PENTRU FIZICA TEHNICA-IFTRA;LEIBNIZ-INSTITUT FUER FESTKOERPER- UND WERKSTOFFFORSCHUNG DRESDEN E.V.;POLITECHNIKA WARSZAWSKA;EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH;PANEPISTIMIO IOANNINON";"DE;UK;FR;RO;PL;CH;EL";/LIF;1;0;0;1;0;0 106862;322581;NOVRIB;ONG;FP7-IDEAS-ERC;ERC-AG-LS1;FP7;Novel Insights into Multi-drug Resistance to Antibiotics and the Primordial Ribosome;2013-02-01;2018-01-31;;"Multi-drug resistant phenotype formation creates global severe clinical threat among the most important challenges facing medicine today, dictating an urgent need for novel approaches. We aim to reveal the scope and mechanisms of resistance in pathogens, by studies that have not been pursued so far worldwide. In parallel we initiated innovative research towards understanding the ribosome origin, aiming at illuminating the transition from the primordial RNA world to the contemporary coded translation era, alongside exploring new targets and providing useful clues for antibiotics design. We base our interdisciplinary objectives on our discoveries originating from the ribosomes high resolution structures, the results of our pioneering efforts and subsequent perseverance. By revealing unique properties of genuine pathogens that facilitate their exclusive resistance pathways,instead of depending solely on benign eubacterial models, we expect to gain matchless new insights. As no crystals of ribosomes from pathogens are available, we have initiated crystallographic studies, and present here preliminary results on two pathogenic life threatening bacteria, Staphylococcus aureus (associated with MRSA resistance) and Mycobacterium tuberculosis via Mycobacterium smegmatis that serve as its medical diagnostic tool. We also aim at experimentally defining the intra-ribosome region suggested by us to be a vestige of a prebiotic apparatus (proto-ribosome) by designing autonomous molecular entities with catalytic capabilities. Constructs the bind substrates have already been obtained. The expected enhancement in understanding peptide bond formation should lead to novel insights into this universal essential process. Our studies are designed to provide unprecedentedly powerful new tools for minimizing pathogens resistance thus should be of immense therapeutic relevance & will open up new horizons for researchers seeking response to challenges of the increasing antibiotic resistance.";2487989;2487989;ERC-2012-ADG_20120314;/ERC-AG;WEIZMANN INSTITUTE OF SCIENCE;IL;;;"/BIO;/LIF";1;0;0;1;0;0 192057;617451;RACEFACEID;ONG;FP7-IDEAS-ERC;ERC-CG-2013-SH2;FP7;Race Matter: On the Absent Presence of Race in Forensic Identification;2014-09-01;2019-08-31;;"This ethnographic project on race in forensic practice aims to study how technologies of identification shape race. The focus is on ‘face-making’ in forensic identification; i.e. the reconstruction of faces of unknown persons, a practice entwined with ‘race-making’. In five subprojects the study investigates: How technologies of facial identification in and outside laboratories enact race (subprojects 1-3); How versions of race change as knowledge moves across sites (subproject 4); The mechanism through which race becomes an absent present object, i.e. an object that appears to the surface, e.g. in discourse, to then go underground to hide in the routines and technologies of science, e.g. in genetic markers (subproject 5). The overall objective of this interdisciplinary project is to develop theoretical concepts and methods to grasp the absent present object race. The project goes beyond the social constructivist paradigm, by taking the biological into account. It attends to the materiality of race, i.e. the ways race is shaped as a set of relations between the biological, the social and the technical. This project is innovative in several ways. It is the first to comprehensively study race and forensics, a highly relevant field where knowledge circulates constantly between science and society. The ethnographic subprojects are innovative in the way they compare frontier science of genetics to every day practices, such as facial composite drawings and skull-based reconstructions. Because of its focus on race-in-practice, this project will make a major contribution to the social sciences by providing tools to theorize the materiality of race. Finally, this innovative project comprises a multi-sited ethnography that follows routes of knowledge into and out of the laboratory to various sites in society.";1999935;1999935;ERC-2013-CoG;/ERC-CG;UNIVERSITEIT VAN AMSTERDAM;NL;;;"/SCI;/SOC";1;0;0;1;0;0 189101;619488;CarrICool;ONG;FP7-ICT;ICT-2013.3.1;FP7;Modular interposer architecture providing scalable heat removal, power delivery, and communication;2014-01-01;2017-06-30;;Modular interposer architecture providing scalable heat removal, power delivery and communicationCarrICool will deliver a game-changing 3D packaging platform for scale-up of future, many-core, Exascale computing systems. The project will also develop a strategic supplier base in Europe for high-end HPC components and systems integration capabilities in the Exascale era. In CarrICool, advanced More-than-Moore components required to scale to energy efficient ExaFLOP computing performance will be developed and integrated into a modular and multifunctional interposer. Four critical packaging elements are implemented on the CarrICool interposer: i) Improved structural and electrical performance will be provided by expansion matching and high wiring density. ii) low thermal gradients for Beyond-CMOS and silicon photonic devices will be provided by integrated, single-phase, water-cooling cavities. iii) High granularity, distributed Buck-converters using integrated, high-quality power inductors will support energy-efficient power delivery to heterogeneous chip stacks. iv) Off-chip bandwidth will be enabled through low-cost and low-loss passive optical coupling to silicon photonic wave guides. CarrICool is targeting 2-fold improvement in heat removal, 10-fold higher voltage granularity and a 10-fold cost reduction in photonic packaging.Advanced characterization and simulation techniques will be implemented using physics-of-failure-based lifetime modelling to provide design-rules for improved system architecture. The performance of the four packaging elements of the modular interposer will be validated on three separate demonstrators and then integrated on the main CarrICool demonstrator. The CarrICool consortium pools interdisciplinary excellence, uniting ten partners from global companies (2), European SMEs (3), institutes (3) and academia (2) across seven European countries. An Advisory Board ensures the alignment of the project goals with user needs.;5848939;4042847;FP7-ICT-2013-11;/CP;IBM RESEARCH GMBH;CH;"AMIC ANGEWANDTE MICRO-MESSTECHNIK GMBH;INSTYTUT TECHNOLOGII ELEKTRONOWEJ;FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.;EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH;Optocap Ltd;TECHNISCHE UNIVERSITAET CHEMNITZ;MURATA INTEGRATED PASSIVE SOLUTIONS;UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK";"DE;PL;CH;UK;FR;IE";/INF;1;0;0;1;0;0 192031;609823;ASIA;ONG;FP7-IDEAS-ERC;ERC-2013-SyG;FP7;Beyond Boundaries: Religion, Region, Language and the State;2014-09-01;2020-08-31;;The Gupta dynasty dominated South Asia during the 4th and 5th centuries. Their period was marked by political stability and an astonishing florescence in every field of endeavor. The Gupta kingdom and its networks had an enduring impact on India and a profound reach across Central and Southeast Asia in a host of cultural, religious and socio-political spheres. Sometimes characterized as a ‘Golden Age’, this was a pivotal moment in Asian history. The Guptas have received considerable scholarly attention over the last century, as have, separately, the kingdoms of Central and Southeast Asia. Recent advances notwithstanding, knowledge and research activity are fragmented by entrenched disciplinary protocols, distorted by nationalist historiographies and constrained by regional languages and associated cultural and political agendas. Hemmed in by modern intellectual, geographical and political boundaries, the diverse cultures, complex polities and varied networks of the Gupta period remain specialist subjects, little-mentioned outside area studies and traditional disciplinary frameworks. The aim of this project is to work beyond these boundaries for the first time and so recover this profoundly influential dispensation, presenting it as a vibrant entity with connections across several regions and sub-continental areas. To address this aim, three PIs have formed an interdisciplinary team spanning linguistics, history, religious studies, geography, archaeology, Indology, Sinology and GIS/IT technologies. This team will establish a scientific laboratory in London that will generate the synergies needed to delineate and assess the significance of the Gupta Age and its pan-Asian impacts. The project's wider objective is to place Central,South and Southeast Asia on the global historical stage, significantly influence practices in Asian research and support EU leadership in Asian studies.;8053715,4;8053715,4;ERC-2013-SyG;/ERC-SyG;BRITISH MUSEUM;UK;"SCHOOL OF ORIENTAL AND AFRICAN STUDIES, UNIVERSITY OF LONDON;THE BRITISH LIBRARY BOARD";UK;/SCI;1;0;0;1;0;0 188652;614768;PROduCTS;ONG;FP7-IDEAS-ERC;ERC-CG-2013-LS9;FP7;Predicting environment-specific biotransformation of chemical contaminants;2014-06-01;2019-05-31;;The ability to predict rates and products of microbial biotransformation for a broad variety of chemical contaminants accurately is essential not only for chemical risk management but also in the context of contaminated site remediation or the development of green chemical alternatives. Existing prediction methods, however, fall short of fulfilling these needs mostly because they base predictions on chemical structure only, disregarding the microbial communities responsible for degradation and their actual metabolic potential as shaped by environmental conditions. The long-term goals of the proposed research are to develop the scientific basis and appropriate modeling algorithms for considering the metabolic potential of environmental microbial communities (i.e., the available pools of catalytic enzymes) in biotransformation prediction. It is proposed that enzyme-catalyzed biotransformation reactions are established as the explicit core elements of biotransformation prediction. The reactions so defined will serve as mechanistic basis to (i) experimentally explore the linkage between microbial community gene expression profiles and their observed potential for contaminant biotransformation, and (ii) use chemometrics and pattern analysis in high-dimensional space to mine environment-specific chemical biotransformation data for probabilities of biotransformation reactions. The resulting novel algorithms for the environment-specific prediction of biotransformation rates and products will be implemented into an existing, publically-accessible biotransformation prediction system (http://www.umbbd.ethz.ch/predict). The proposed research is highly interdisciplinary and will profit from the most recent technological and scientific advances in the fields of analytical chemistry, molecular biology and chemo-/bioinformatics to develop a ground-breaking approach for profiling the capacity of microbial communities for contaminant biotransformation.;1996352;1996352;ERC-2013-CoG;/ERC-CG;EIDGENOESSISCHE ANSTALT FUER WASSERVERSORGUNG ABWASSERREINIGUNG UND GEWAESSERSCHUTZ;CH;;;"/BIO;/LIF;/SCI";1;0;0;1;0;0 189914;625082;SPLICING IN MITOSIS;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IOF;FP7;Regulation of cell division by alternative splicing;2015-01-01;2017-12-31;;"The complexity of the mammalian proteome is far more extensive than can be explained by a simple one gene: one protein paradigm. The use of alternative splicing (AS) is emerging as a core regulatory mechanism, in a similar way to whether a specific gene is transcribed or repressed, or a protein is degraded or stabilised. Also like both transcriptional and post-translational control, it seems that almost every gene in the human genome undergoes AS. Despite this, the role of AS in a fundamental cellular process, such as cell division is still poorly understood. This proposal aims to tackle this problem by assessing the role of AS in cell division. The recent identification that the machinery involved in splicing, the spliceosome, is regulated by post-translational modifications (PTMs) during cell division strongly suggests AS, alongside PTMs, may have a core regulatory role in mitosis. This project proposal is therefore timely and will gain insights into this universal cellular process. I will use a multidisciplinary approach of combining next-generation mRNA sequencing in human cells to take snapshots of multiple stages of cell division with validation using proteomic datasets. Further validation of individual candidates will be done by high-throughput fluorescence microscopy to discover potential novel regulators of cell division. Furthermore, I will assess the segments removed by AS for functional modules known to modulate protein abundance and stability. A web-based relational database will be developed to disseminate our findings to the scientific community This proposal will assess the occurrence of splice variants during mitosis and aims to discover new regulators of cell division. The interdisciplinary approach and the data produced in this proposal will be highly beneficial for future research. More importantly, the research results will further our understanding a number of major diseases, such as cancer, which are a major socioeconomic concern in Europe.";271868,4;271868,4;FP7-PEOPLE-2013-IOF;/MC-IOF;MEDICAL RESEARCH COUNCIL;UK;;;/LIF;1;0;0;1;0;0 189912;624943;MIDGETRAP;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IEF;FP7;An innovative semiochemical based tool for monitoring and control of biting midge vectors of bluetongue and Schmallenberg disease;2014-08-18;2016-08-17;;"This proposal responds to an urgent need to increase agricultural production by improving monitoring and control of animal diseases. This will be achieved through development of a new tool for capturing biting midges: vectors of Bluetongue and Schmallenberg disease which threaten food production across Europe. The key deliverable will be a lure that uses odours isolated from manure and urine to attract midges to a non-powered trap. This represents a major advance from the state of the art, as there is currently no suitable tool for sustainable, wide-spread monitoring of biting midges. The project is an international collaboration between a highly-talented researcher (Dr Daniel Bray, Keele University, UK) and a world-class scientist (Prof. Rickard Ignell, SLU, Sweden), which will draw on the expertise of an SME to determine how this innovation can be marketed to achieve maximum benefit across Europe. Through training and research, the project will: (a) advance the fellow’s skills in entomology through engagement with an interdisciplinary project team (b) improve the fellow’s capacity to lead research projects targeting insect disease vectors (c) produce a cost-effective trap for sustainable monitoring of biting midges (d) foster collaboration between academia and industry through translational research (e) allow the fellow to carry out a placement in industry, to understand how to work in this sector and gain entrepreneurial skills and (f) implement outreach activities which will disseminate our results to those that need them. Greater interaction with SMEs and meeting the societal challenge of sustainable food production are key aims of the Europe 2020 programme addressed by this proposal. The training and networking opportunities will advance the researcher towards his career goal of obtaining an independent position in integrated pest management, and enhance the capacity of the ERA to conduct world-leading agricultural and entomological research.";266599,6;266599,6;FP7-PEOPLE-2013-IEF;/MC-IEF;SVERIGES LANTBRUKSUNIVERSITET;SE;;;;1;0;0;1;0;0 191274;617393;CAUSALPATH;ONG;FP7-IDEAS-ERC;ERC-CG-2013-PE6;FP7;Next Generation Causal Analysis: Inspired by the Induction of Biological Pathways from Cytometry Data;2015-01-01;2019-12-31;;"Discovering the causal mechanisms of a complex system of interacting components is necessary in order to control it. Computational Causal Discovery (CD) is a field that offers the potential to discover causal relations under certain conditions from observational data alone or with a limited number of interventions/manipulations. An important, challenging biological problem that may take decades of experimental work is the induction of biological cellular pathways; pathways are informal causal models indispensable in biological research and drug design. Recent exciting advances in flow/mass cytometry biotechnology allow the generation of large-sample datasets containing measurements on single cells, thus setting the problem of pathway learning suitable for CD methods. CAUSALPATH builds upon and further advances recent breakthrough developments in CD methods to enable the induction of biological pathways from cytometry and other omics data. As a testbed problem we focus on the differentiation of human T-cells; these are involved in autoimmune and inflammatory diseases, as well as cancer and thus, are targets of new drug development for a range of chronic diseases. The biological problem acts as our campus for general novel formalisms, practical algorithms, and useful tools development, pointing to fundamental CD problems: presence of feedback cycles, presence of latent confounding variables, CD from time-course data, Integrative Causal Analysis (INCA) of heterogeneous datasets and others. Three features complement CAUSALPATH’s approach: (A) methods development will co-evolve with biological wet-lab experiments periodically testing the algorithmic postulates, (B) Open-source tools will be developed for the non-expert, and (C) Commercial exploitation of the results will be sought out. CAUSALPATH brings together an interdisciplinary team, committed to this vision. It builds upon the PI’s group recent important results on INCA algorithms.";1724000;1724000;ERC-2013-CoG;/ERC-CG;PANEPISTIMIO KRITIS;EL;KAROLINSKA INSTITUTET;SE;"/PSE;/ICT;/TEL;/NET";1;0;0;1;0;0 192578;618731;THEATRICALITY;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-CIG;FP7;The Antitheatrical Prejudice: Roman Ban on Permanent Theater and the Triumph of Pompey;2015-01-01;2018-12-31;;This study examines the cultural and political processes leading to the institution and resolution of the (unwritten) ban on the permanent theater, effective in Rome, from 154 BCE until the construction of Pompey’s Theater-Portico Complex (61-55 BCE). Previously approached from the viewpoint provided through textual evidence, the crisis of the permanent theater has been interpreted as a power struggle between masses and the Roman elite. Building on my dissertation research, this work takes a new perspective. By situating the issue in an interdisciplinary Hellenistic context, my project presents the crisis of permanent theater as an inter-elite problem, a struggle between the Roman Senate and powerful political actors like Gnaeus Pompeius Magnus (“the Great”). To demonstrate this point, using historical and archaeological evidence, I analyze spatial development of Roman theater buildings in South Italy and Sicily parallel to the urban development in Rome in the period between the introduction of the Greek theater to Rome in 240 BCE and the construction of Pompey’s Theater-Portico Complex. I focus on the monuments alongside the triumphal path leading to Pompey’s monument. The exploration of theater and urban space is carried out together with narrative analysis of theatrical performances, processions and sacrifice, which occasionally take place in the context of a civic festival or triumphal celebration. An accompanying reconstruction of the theatrical events and triumphal procession in Rome concluding at Pompey’s Theater-Portico complex illuminates how Roman theater building and urban space worked politically before and during the First Triumvirate. The three dimensional images produced by the research team illustrate theatrical moments increasing the popular appeal of published results. This study establishes cultural connections between the Hellenistic East and the Republican Rome contributing to European history and recent debates on globalization.;100000;100000;FP7-PEOPLE-2013-CIG;/MC-CIG;ALTINBAS UNIVERSITESI;TR;;;/LIF;1;0;0;1;0;0 192454;643330;PIPERS;ONG;FP7-COH;FP7-CDRP-2013-EUR-CD;FP7;Policy into Practice: EURAXESS Researcher Skills for Career Development;2014-10-13;2017-02-12;;"The PIPERS project (Policy into Practice: EURAXESS Researcher Career Skills for Career Development) is led by the British Council along with 5 partners and 15 associated Third Parties from both the EURAXESS Service Network and other academic and non-academic stakeholders from across Europe and Israel. Its aim is to support researcher career development. To do so the project will identify and cascade existing good practice and training resources, develop new tools to support proactive management of researcher career paths and provide an efficient and sustainable way of disseminating these across the Network. The objectives of the project will be pursued over a 28 month period. Core activities will include policy dialogue with employer stakeholders and groups representing researchers’ interests; dissemination of good policy practice and training resources in researcher career development through the development of an e-platform and the delivery of nine “train the trainer” workshops for researcher career development staff and four demonstration workshops with researchers; and the development and testing of a self-assessment tool for researchers to enable them to be proactive in their professional and career development. By identifying existing best practice and resources from the EURAXESS Service Networks and the wider research community and bringing staff from these institutions together to learn how to best cascade the training, the project will both strengthen interaction between research institutions in the management of research careers and ensure the relevance of the resources. Researchers will be able to set personal targets and demonstrate evidence of achievements based on knowledge and behaviours which will help them to navigate often complex research careers, both within academia and industry as well as skills such as information literacy, leadership, interdisciplinary working and public engagement which will help them to maximise the impact of their research.";610650,07;569590,92;FP7-CDRP-2013-EUR-CD;/CSA-CA;THE BRITISH COUNCIL;UK;"ETHNIKO KENTRO EREVNAS KAI TECHNOLOGIKIS ANAPTYXIS;FUNDACION ESPANOLA PARA LA CIENCIA Y LA TECNOLOGIA;MASINSKI FAKULTET - UNIVERZITETA U NISU;UNIVERSITY OF DURHAM;SOFIISKI UNIVERSITET SVETI KLIMENT OHRIDSKI";"EL;ES;RS;UK;BG";;1;0;0;1;0;0 188672;615640;FOREFRONT;ONG;FP7-IDEAS-ERC;ERC-CG-2013-PE6;FP7;Frontiers of Extended Formulations;2014-09-01;2019-08-31;;"'Linear programming has proved to be an invaluable tool both in theory and practice. Semidefinite programming surpasses linear programming in terms of expressivity while remaining tractable. This project proposal investigates the modeling power of linear and semidefinite programming, in the context of combinatorial optimization. Within the emerging framework of extended formulations (EFs), I seek a decisive answer to the following question: Which problems can be modeled by a linear or semidefinite program, when the number of constraints and variables are limited? EFs are based on the idea that one should choose the 'right' variables to model a problem. By extending the set of variables of a problem by a few carefully chosen variables, the number of constraints can in some cases dramatically decrease, making the problem easier to solve. Despite previous high-quality research, the theory of EFs is still on square one. This project proposal aims at (i) transforming our current zero-dimensional state of knowledge to a truly three-dimensional state of knowledge by pushing the boundaries of EFs in three directions (models, types and problems); (ii) using EFs as a lens on complexity by proving strong consequences of important conjectures such as P != NP, and leveraging strong connections to geometry to make progress on the log-rank conjecture. The proposed methodology is: (i) experiment-aided; (ii) interdisciplinary; (iii) constructive.'";1455479;1455479;ERC-2013-CoG;/ERC-CG;UNIVERSITE LIBRE DE BRUXELLES;BE;;;"/PSE;/ICT;/TEL;/NET";1;0;0;1;0;0 189838;617107;O2SENSE;ONG;FP7-IDEAS-ERC;ERC-CG-2013-PE4;FP7;Oxygen Sensing with Multimodality Imaging Probes;2014-09-01;2019-08-31;;"'This programme will employ physical sciences and biomedicine techniques to develop a revolutionary approach to early cancer diagnosis and post-treatment monitoring aiming to address shortcomings in our current technology in oxygen sensing and imaging of hypoxic prostate tumours. This proposal represents a gearing process towards the biomedical implementation of metal complexes and functionalised nanoparticles as novel synthetic platform systems for personalised diagnosis and treatment of diseases such as cancer and which can also be extended to neurodegenerative disorders. The work programme is a meeting point for interdisciplinary science that goes well beyond state of the art. New chemical sensing devices will outstrip and supersede existing biopsy and imaging techniques used in diagnosis and treatment of diseases such as cancers. The key advances of this programme will be: (a) ‘smart’ all-in-one multimodal imaging probes, whose sensitivities to levels of oxygen in cells (pO2) will be tunable to respond to various levels of hypoxia in tumors as desired. Our ultra-sensitive probes will be effective at low O2 concentrations and respond to reduced levels of hypoxia and under anoxia. This will surpass the mainstay in cancer diagnosis and therapy and provide increased selectivity for a wider range of tumours. (b) new probes suitable for interlocked Positron Emission Tomography (PET), Single Photon Emission Tomography (SPECT), and optical imaging methodologies Simultaneous in vitro and in vivo diagnostic information from radioimaging techniques (PET, SPECT) and optical imaging will provide in depth understanding of biological processes and lead to personalised medicine. (c) new imaging tools for the first time will monitor the cellular biolocalisation of these probes by multiphoton optical imaging in nearIR regimes. These will drive the development of time-gated microscopy and multi-photon imaging with sensitivity for various levels of tumour hypoxia.'";1886876;1886876;ERC-2013-CoG;/ERC-CG;UNIVERSITY OF BATH;UK;;;"/PSE;/SCI";1;0;0;1;0;0 189972;629785;HTSCS IN PLACENTA;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IEF;FP7;Origin and lineage specification of trophoblast cells in early human placenta;2014-09-01;2016-08-31;;"My central question: how does the human placenta develop and how are specialized trophoblast sub-types generated? Despite advances in placental biology, pregnancy disorders occur frequently with few treatment options available, resulting in considerable maternal and/or infant mortality and morbidity. The cause of these disorders is abnormal early placental development but ethically and practically this is hard to investigate. Developing in vitro models that are truly representative of normal first trimester trophoblast will allow investigation of lineage specification and differentiation. I will take an interdisciplinary approach to characterize the first trimester villous cytotrophoblast (VCT) population. Specifically, I aim to: 1. Characterize the expression of trophoblast stem (TS) cell transcription factors and epigenetically regulated genes to identify the anatomical compartment(s) containing population(s) with stem cell characteristics 2. Isolate VCT using a specific cell surface marker and perform an in-depth molecular characterization at a single cell level to identify putative TS cells 3. Characterize cell signalling pathways in the VCT and in the putative TS cell population 4. Establish cell culture conditions for TS cells 5. Perform a detailed characterization of cells cultured in vitro This proposal has arisen from preliminary results obtained working in Centre for Trophoblast Research, University of Cambridge. Working in a lab with extensive experience of trophoblast isolation (Prof. A.Moffett) and input from our collaborators, Dr. M.Hemberger and Prof. G.Burton who have experience in mouse TS cells and human placental function in vivo, respectively has been pivotal. I am thus in an ideal position to capitalize on this expertise together with other stem cell labs in Cambridge to develop essential tools and knowledge to understand early developmental processes during placentation. It also has important translational impact for women and their babies.";231283,2;231283,2;FP7-PEOPLE-2013-IEF;/MC-IEF;THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;UK;;;;1;0;0;1;0;0 189860;618520;THUNDER;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-CIG;FP7;Through Understanding of Socioeconomic Metabolism towards Sustainability;2014-05-01;2017-04-30;;'The aim of this research project is to identify the link between environmental problems and their drivers. While production activities are responsible for most of the environmental impacts, they are ultimately driven by the final consumption of goods and services. This project will focus on further development of footprint indicators (indicators which assign environmental burden from the whole production chain to final consumers) by their integration into environmentally extended multiregional input-output analysis. Some indicators, such as human appropriation of net primary production, will be calculated from the consumer responsibility perspective for the first time and others, such as nitrogen footprint, will be for the first time integrated into a multi-regional input-output framework. A consolidated set of footprint indicators will be established for the most important environmental problems identified by other researchers. It will provide policy makers with evidence regarding environmental burdens abroad induced by domestic consumption. The set of footprint indicators will help them to measure progress in environmental areas and set up policy goals. A set of footprint indicators is necessary in order to avoid shifting environmental burden from one region to another and across environmental areas. This interdisciplinary project bridges economics and natural sciences and utilizes knowledge from both.';75000;75000;FP7-PEOPLE-2013-CIG;/MC-CIG;UNIVERZITA KARLOVA;CZ;;;/LIF;1;0;0;1;0;0 189050;619228;ISS-EWATUS;CLO;FP7-ICT;ICT-2013.6.3;FP7;Integrated Support System for Efficient Water Usage and Resources Management;2014-02-01;2017-01-31;;"The proposed project is an interdisciplinary effort of specialists from water management and ICT research respectively to develop an intelligent Integrated Support System for Efficient WATer USage and resources management (ISS-EWATUS). The project will develop several innovative ICT methods aiming to exploitthe untapped water-saving potential in EU. The overall goal will be achieved by developing an innovative, multi-factor system capable to optimise water management and reduce water usage.
At household level:a) an information system for gathering data about water usage is planned to increase the awareness of water consumption; the data will be interpreted and presented to household consumers in an understandable way using mobile devices (smartphones, tablets),b) a household Decision Support System (DSS) will be developed for mobile devices to reduce water consumption. Recommendations regarding water-saving devices and behaviour will be produced,c) a social-media platform will be developed to reinforce water-saving behaviour of consumers via the social interactions among users (and between consumers and experts of water-saving techniques).
At urban level:a) an innovative decision support system for reducing leaks in the water delivery system will be built based on the dynamic modifications of pumping schedules to reduce leakages at municipal level,b) an adaptive pricing policy will be developed as the economic instrument to induce water-saving behaviourand reduce peaks in water and energy distribution loads.
Being validated at two differently characterised locations, the ISS-EWATUS will be sufficiently flexible to be exploited in any EU location. Appropriate training, manuals and dissemination will give people across EU an efficient tool for water conservation. The solutions of ISS-EWATUS for households will be available on the mobile applications portals. The rest of solutions will be offered to water management companies in EU.";3346313;2427585;FP7-ICT-2013-11;/CP;UNIWERSYTET SLASKI;PL;"DIMOTIKI EPICHEIRISI YDREFSIS - APOCHETEFSIS SKIATHOU;REJONOWE PRZEDSIEBIORSTWO WODOCIAGOW I KANALIZACJI W SOSNOWCU SA;INSTYTUT EKOLOGII TERENOW UPRZEMYSLOWIONYCH;UNIVERSIDAD PABLO DE OLAVIDE;ETHNIKO KENTRO EREVNAS KAI TECHNOLOGIKIS ANAPTYXIS;STICHTING VU;DOTSOFT OLOKLIROMENES EFARMOGES DIADIKTIOY KAI VASEON DEDOMENON AE;LOUGHBOROUGH UNIVERSITY;BRUNEL UNIVERSITY LONDON";"EL;PL;ES;NL;UK";/INF;1;0;0;1;0;0 188202;627688;SICSAR;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IEF;FP7;Social Interaction Characteristics for Socially Accepted Robots;2014-09-15;2016-11-13;;"'Why robotic research, despite its advances, has not yet lead to the widespread use of robots in operative contexts treatable through human-robot cooperation? The SICSAR project proposes that the main reason resides not in intrinsic technical difficulties, but in the limits of the diffused expectation that, to collaborate with humans, robots need to be almost 'perfect' - faultless - in their actions. Humans are certainly not perfect agents, and, to achieve common goals during interactions, mutually correct their behaviors to increase their possibilities of success. Transferring this self-other corrective dynamics to human-robot cooperation could be the key to effectively renew the approach to implement this kind of collaboration: renouncing to build 'perfect' robots, and focusing on creating 'social' robots, that is, robots able to correct their behaviors on the basis of their capability to understand humans' signals. The proposed project aims at taking a fundamental step in this direction: developing robots able to coordinate their behaviors with those of their human partners. Today this represents a frontier issue also and specifically for HRI and social robotics, which see human-robot 'behavioral coordination' as a sine qua non condition to integrate robots in our social context(s). The project tackles this issue through a highly interdisciplinary approach, integrating HRI with experimental psychology, robotics and robot design research. It intends to develop hardware and software solutions providing iCub - one of the most sophisticated European robots – with a new ability: competently correlating and synchronizing its interactive movements with those of its human partners during dyadic interactions. As argued in the proposal, the project is expected to have an impact not only on European robotics' scientific, technological, industrial and commercial competitiveness, but also on some aspects of the current socio-economic setting of the industrialized world.'";187414,8;187414,8;FP7-PEOPLE-2013-IEF;/MC-IEF;FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA;IT;;;;1;0;0;1;0;0 188243;628273;GUT IMMUNITY GRNS;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IEF;FP7;Characterizing the Gene Regulatory Networks Mediating Gut Immunocompetence in Drosophila;2014-09-01;2016-08-31;;The emergence of a gastrointestinal tract within the body cavity is one of the major innovations in animal evolution allowing the transition from an intra- to an extracellular mode of digestion. With this emergence came the opportunity for infectious agents to exploit this intestinal ecosystem for their own transmission. Gut-bearing organisms therefore evolved complex mechanisms to defend themselves against these agents, making them “gut immunocompetent”. This involved a process of continuous adaptation and counter-adaptation in the two competing species, host and pathogen, rendering gut immunocompetence a complex trait with a large genetic component. Important progress has been made to elucidate the biological processes underlying gut immunocompetence, revealing an intricate interplay between immunological, stress, and neuronal signaling as well as gut regeneration and wound repair. However, how this multilayered regulatory network is encoded at the molecular level and how genetic variation of the host species contributes to this trait is still poorly understood. Here, we propose a global and interdisciplinary study, combining regulatory genomics and bioinformatics, to elucidate the genetic and molecular mechanisms underlying gut immunocompetence and its variation in Drosophila melanogaster. By determining the regulatory targets of transcription factors involved in the interplay between the immune response pathways, relating them to known physiological outputs, and computationally mining the genetic variants that may lie at the basis of the observed phenotypic variation, we expect to elucidate the regulatory networks mediating gut immunocompetence and how they are impacted by genomic variation. This would not only constitute a breakthrough in the field of innate immunity, but a sound foundation for understanding the molecular driving forces that impact genetic variation of a complex trait in general.;268685,6;268685,6;FP7-PEOPLE-2013-IEF;/MC-IEF;ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE;CH;;;;1;0;0;1;0;0 188485;339152;Speech Unit(e)s;ONG;FP7-IDEAS-ERC;ERC-AG-SH4;FP7;The multisensory-motor unity of speech;2014-09-01;2019-08-31;;"This project is focussed on the speech unification process associating the auditory, visual and motor streams in the human brain, in an interdisciplinary approach combining cognitive psychology, neurosciences, phonetics (both descriptive and developmental) and computational models. The framework is provided by the “Perception-for-Action-Control Theory (PACT)” developed by the PI. PACT is a perceptuo-motor theory of speech communication, which connects in a principled way perceptual shaping and motor procedural knowledge in speech multisensory processing. The communication unit in PACT is neither a sound nor a gesture but a perceptually shaped gesture, that is a perceptuo-motor unit. It is characterised by both articulatory coherence – provided by its gestural nature – and perceptual value – necessary for being functional. PACT considers two roles for the perceptuo-motor link in speech perception: online unification of the sensory and motor streams through audio-visuo-motor binding, and offline joint emergence of the perceptual and motor repertoires in speech development. This provides the basis for the two parts of the project. In the “Extracting Units” action, we shall study how audio-visuo-motor speech units are extracted online in the human brain. This involves analysis of the joint properties of audio, video and motor stimuli gathered in a multimodal corpus; behavioural and neurophysiological data on the extraction of coherent streams within a speech scene and on the segmentation of streams into coherent audiovisual units; and elaboration of neurocomputational models of the audio-visuo-motor binding process. In the “Developing Units” action, we shall gather phonetic data on the joint development of perception, action and phonology, and implement and test various kinds of computational models, to assess how perceptuo-motor speech units emerge and evolve in the course of acquisition, reacquisition, evolution or learning of a given phonological system.";2499249;2499249;ERC-2013-ADG;/ERC-AG;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FR;;;/MED;1;0;0;1;0;0 188241;628215;E-GNOSIS;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IEF;FP7;e-Gnosis: a novel platform technology for quantitative mobile diagnostics;2014-05-01;2016-07-30;;"The aim is to produce a platform technology that combines the price-point and ease-of–use of lateral flow immunoassays with high-sensitivity, quantitative measurements currently requiring capital intensive equipment. This could ultimately allow its use as a consumer-technology, to diagnose and monitor health. e-Gnosis is an interdisciplinary project combining the current state-of-the-art in recessed ring-disk nanoelectrode arrays with a novel signal amplification strategy in the form of ferrocene loaded pH sensitive polymer nanobeads. e-Gnosis will combine these technologies to produce a multiplexed biosensor chip capable of running several ultra-high sensitivity immunoassays without the need for complex or expensive read-out equipment. The use of nanostructured electrode arrays allows the local pH to be changed electrochemically, such that the pH sensitive beads bound to the analyte dissolve and release ferrocene, leading to a large, proportional signal amplification of each binding event. Amplification can be triggered without external reagent addition and, importantly, without necessitating a wash step to remove unbound labels (the rapid initial current peak is bound to originate from within the nanostructures). Performance characteristics will include low sample volume requirement, sensitivity, limit of detection, robustness to interferrents, dynamic range and speed to result. Fabrication is based on highly parallel semiconductor fabrication technology and standard methods for antibody immobilisation, allowing low cost production. The e-Gnosis platform can also be used for other affinity based recognition events. Apart from the potential commercial and societal benefits of such a sensing technology, the project will also produce two enabling methods within nanofabrication and surface functionalisation. The project feeds into key areas identified by EU and industry stakeholders within ETP Nanomedicine and Horizon 2020, amongst others.";230943,6;230943,6;FP7-PEOPLE-2013-IEF;/MC-IEF;NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU;NO;;;;1;0;0;1;0;0 188163;629304;SEPHARAB;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IEF;FP7;Sephardi Halakhic Literature and Ladino Rabbinic Language;2014-06-01;2016-05-31;;"The goal of this project is the study of practical halakhic guides for religious observance written by Sephardi rabbis in Judeo-Spanish between the 16th and 20th centuries, in their social and religious contexts. The Ladino rabbinic texts under discussion were printed in Hebrew letters and include elements of diverse linguistic origins, among them, elements from Hebrew and Aramaic. Researchers dealing with these texts need to have an interdisciplinary background combining both Jewish and Hispanic studies, in addition to other fields. The project description has three foci: 1) the intensive complementary training program of the researcher, who already has solid prior scholarly experience in the field of Ladino rabbinic language and literature; 2) the nature of the cooperation between the research trainee and the local authority in Jewish languages (Ladino, Yiddish), and the means the latter will use to supervise the trainee’s work; 3) the framework in which the training will take place, at the highest-level Ladino studies program in Israel, in its most prestigious faculty of humanities. The principal objectives for the researcher’s training, which are intended to have a significant impact on the furtherance of her scholarly career, are: bibliographical data gathering at the richest libraries of Ladino literature in Israel; a fine-tuning of the researcher’s training in Ladino linguistics and literature; the undertaking of a comparative Jewish interlinguistic study of Ladino and Yiddish rabbinical texts; the organization of an international conference on Ladino and Yiddish rabbinical literature; the assuming by the trainee of teaching responsibilities at the host institution; and the improvement of the researcher’s knowledge of Hebrew, as well as her acquisition of Yiddish linguistic skills and familiarity with Yiddish rabbinical literature. The expected results will include a survey of the most representative authors and works of halakhic literature in Ladino and Yiddish; a formulation of the salient characteristics and subgenres of these works; an analysis of the purposes the halakhic works were meant to serve; a study of their contents (laws, prayers and religious practices; moral teachings, rabbinic tales, folklore, popular culture; and private and public life of the Sephardic Jews scattered thorough the Mediterranean basin); and an analysis of the linguistic varieties of Ladino in which the works were written.";184558,8;184558,8;FP7-PEOPLE-2013-IEF;/MC-IEF;THE HEBREW UNIVERSITY OF JERUSALEM;IL;;;;1;0;0;1;0;0 188237;628151;IDPSF;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IEF;FP7;Professionals and Parenthood in the Twenty-first Century;2014-10-01;2016-09-30;;"This project aims to contribute to a better understanding of work-life conflict and the negotiation of parenthood in professional service firms (PSFs) from a cross-national comparative perspective (France, Romania and the UK). These countries provide very different cultural and institutional settings and as work and parenting norms are culturally and institutionally shaped, conducting cross-national research will allow a more nuanced understanding of the complex interactions between the two. PSFs provide particularly rich settings to study work-life conflict due to the long working hours and client availability requirements. As knowledge-intensive firms, the value of PSFs is based primarily on their professional workers. Developing and keeping their human resources is therefore fundamentally important to PSFs in terms of competitiveness, productivity, professional integrity and reputation. In-depth interviews will be used to examine how professional identities and parenthood are embedded within organizational policies and practices shaped by national contexts. This research is innovative as it takes a holistic view of parenting and work-life conflict by adopting a multilevel approach and by focusing on parenthood rather than motherhood. This project is very timely as it addresses directly two key issues currently on the agenda of the EU and its member states: (1) the matter of gender diversity in economic leadership positions; and (2) the impact of parental leave on professionals’ careers, as well as reinsertion upon return. In addition, my project is highly relevant to the ERA as: (1) it is interdisciplinary, (2) it provides me with excellent training and international collaborations which will significantly advance my future career. Against the backdrop of globalization and economic recession, my research will contribute to making Europe a more competitive and more dynamic knowledge-based economy.";231283,2;231283,2;FP7-PEOPLE-2013-IEF;/MC-IEF;CITY UNIVERSITY OF LONDON;UK;;;;1;0;0;1;0;0 188235;628138;STRONG NEUTRAL-ION;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IEF;FP7;Strong interactions of periodically-driven trapped ions, cold atoms and molecules;2014-10-01;2016-09-30;;"In the proposed project we will develop a theoretical framework for analyzing periodically-driven phases of ultracold matter in a nonperturbative way, focusing on a general understanding of the structure of solution sets in parameter space. This will enable us to present original ideas for reaching new regimes of quantum many-body physics. Cold, trapped, strongly interacting ionic and neutral atoms and molecules, subject to periodic electromagnetic fields, will be studied using novel analytical and numerical tools. We will investigate new ideas for sympathetic cooling of particles trapped in oscillating fields, and we will study soliton and vortex solutions nucleated about crystallized ions immersed in a BEC. The proposed theoretical research will be accompanied by exchange of ideas and close collaboration with leading experimental groups, aspiring to advance the scientific and technological fronts of the field with impact also in emerging interdisciplinary fields such as cold quantum chemistry. Moreover, the mathematical framework employed to describe the periodically trapped interacting atomic systems, will be applied to a deep and innovative analysis of Floquet topological insulators – yielding completely new results in a different field, yet one which has close connection and can be realized with cold atomic systems. As a unique outreach activity, the fellow will initiate a two-year project to guide high-school students in original research work, following a similar successful project that he has carried previously. The new project will be planned to involve a small-scale collaboration between students in his home country and the host country.";202405,8;202405,8;FP7-PEOPLE-2013-IEF;/MC-IEF;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FR;;;;1;0;0;1;0;0 188047;626740;PHENINST;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IEF;FP7;The phenomenological concept of institution: event, history, symbolic;2014-09-01;2016-08-31;;"The project aims at illustrating the specificity and fecundity of the phenomenological concept of Stiftung/“institution”. Thanks to its joint reference to the taking place of an event and the opening of a new dimension of meaning, the concept of institution allows us to map out a rich and articulated field of research, the potential of which still awaits to be fully fleshed out in the literature. The project also aims at filling this gap, in particular by writing some papers and a book on the theme. The concept of institution, originally introduced by Husserl, shall be analyzed with reference to several authors belonging to the phenomenological and post-phenomenological tradition: Heidegger, Merleau-Ponty, Derrida and Richir. The aim of the project is to analyze several theoretical issues which the concept of institution allows us to make emerge across the texts of these authors. The project is organized around four theoretical questions and thus structured into four corresponding phases: 1) a general theoretical analysis of the concept of institution as an event – its a-subjective nature, its empirical and transcendental status, its problematic connection to an Urstiftung, the relationship between the event of the institution and the thereby instituted field; 2) the study of the historical institution, with the aim of elaborating the conception of historicity implied by the very concept of institution; 3) the study of the relationship between institution and culture, with the aim of elaborating a conception of the different symbolic formations as “institutions”; 4) an investigation of the relationship between, on the one hand, symbolic and historical institutions, and, on the other, pre-linguistic and perceptual experience. The project also implies a series of interdisciplinary connections in the field of social and human sciences, that I will explore with particular regard to the theory of historiography and anthropology.";194046,6;194046,6;FP7-PEOPLE-2013-IEF;/MC-IEF;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FR;;;;1;0;0;1;0;0 188160;629254;QUANTUM VIBES;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IEF;FP7;Structured Vibrational Environments and Quantum-Coherent Transport in Chiral Systems;2014-11-01;2017-08-09;;"The last few years have seen a renewed and ever increasing interest into the mechanism of electronic energy transfer (EET) during the first steps of photosynthesis stimulated by surprising experimental findings that indicate that EET in natural light-harvesting complexes may involve long-lived quantum-coherent dynamics. EET is a fundamental process relevant not only for biology but also for many applications based on synthetic molecular aggregates. Thus, establishing design principles that support quantum coherent dynamics of electronic excitation in the noisy vibrational environment typical of supramolecular structures may bring paradigmatic changes to the development of quantum-enhanced technologies. This project is directed at investigating the largely unknown structure-to-function relation in coherent transport. The effect of structured environments, in particular discrete vibrations and the structural organisation of the light-harvesting molecules in sustaining quantum coherent dynamics and aiding EET will be studied in novel artificial systems. EET will be treated within the theoretical framework of open quantum systems in the well-known Quantum Mechanics Group at the University of Trieste under the supervision of Dr. A. Bassi. Despite the theoretical nature of the project, the research will have a strong experimental connection by focusing on experimentally relevant synthetic chiral systems that will be subject to spectroscopic studies in the group of Dr. E. Collini at the University of Padova. The IEF program will allow the fellow to be immersed in an international top-class research environment and carry out a truly interdisciplinary research. The competencies gained and collaborations established during the fellowship will strengthen the scientific career of the fellow and contribute towards the fellow’s aim of a long-term research career in Europe. It will thus be beneficial for the fellow and for Europe’s research excellence.";179739,6;179739,6;FP7-PEOPLE-2013-IEF;/MC-IEF;UNIVERSITA DEGLI STUDI DI TRIESTE;IT;;;;1;0;0;1;0;0 188254;628509;SYNTHETIC ECFDEVICES;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IEF;FP7;Extracytoplasmic Function (ECF) Sigma Factors: From Regulatory Specificity to Synthetic Switches;2014-07-01;2016-06-30;;Bacillus subtilis is a model organism for basic and applied research that has been intensively studied for more than two decades in the course of EU-funded research consortia and – with the FP7-project BaSynthec – has recently entered the age of Synthetic Biology (SynBio). This emerging interdisciplinary research area has a huge potential for biotechnological applications and is a major focus of upcoming EU-funded research initiatives, as reflected by the first transnational ERASynBio call this year and the focus of the EU-program Horizon 2020 on innovation and biotechnology. Based on the comprehensive knowledge of B. subtilis biology, its potential as an important chassis for future SynBio applications is unquestioned. But the lack of standardized tools for designing and implementing in vivo expression programs for metabolic engineering currently limits its use. It is the aim of this project to contribute to such a genetic toolbox by exploiting the enormous potential of Extracytoplasmic Function ? factors (ECFs). These transcriptional regulators provide a huge reservoir for developing SynBio switches. But since their diversity, specificity and ubiquitous distribution has only recently been discovered by the host group, ECFs have so far not been used for SynBio purposes. Using the comprehensive knowledge of the host group on B. subtilis genetics, ECF biology, and SynBio rationales, this project aims at developing innovative orthogonal ECF-based switches and devices for controlling complex expression programs in B. subtilis, based on novel actinobacterial ECF groups. The success of this project, set at the interface between basic molecular research and SynBio application, furthermore builds on the applicant’s strong expertise in bacterial genetics, the superb infrastructure of the research environment at the LMU Biocenter, and the support provided to the applicant by the host institution.;161968,8;161968,8;FP7-PEOPLE-2013-IEF;/MC-IEF;TECHNISCHE UNIVERSITAET DRESDEN;DE;LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN;DE;;1;0;0;1;0;0 188505;340528;CellMechanoControl;ONG;FP7-IDEAS-ERC;ERC-AG-PE3;FP7;"The physical basis of cellular mechanochemical control circuits";2014-06-01;2019-05-31;;"Biological cells possess a chemical “sense of smell” and a physical “sense of touch”. Structure, dynamics, development, differentiation and even apoptosis of cells are guided by physical stimuli feeding into a regulatory network integrating biochemical and mechanical signals. Cells are equipped with both, force-generating structures, and stress sensors including force-sensitive structural proteins or mechanosensitive ion channels. Pathways from force sensing to structural and transcriptional controls are not yet understood. The goal of the proposed interdisciplinary project is to quantitatively establish such pathways, connecting the statistical physics and the mechanics to the biochemistry. We will measure and model the complex non-equilibrium mechanical structures in cells, and we will study how external and cell-generated forces activate sensory processes that (i) act (back) on the morphology of the cell structures, and (ii) lead to cell-fate decisions, such as differentiation. The most prominent stress-bearing and -generating structures in cells are actin/myosin based, and the most prominent mechanoactive and -sensitive cell types are fibroblasts in connective tissue and myocytes in muscle. We will first focus on actin/myosin bundles in fibroblasts and in sarcomeres in developing heart muscle cells. We will observe cells under the influence of exactly controlled external stresses. Forces on suspended single cells or cell clusters will be exerted by laser trapping and sensitively detected by laser interferometry. We furthermore will monitor mechanically triggered transcriptional regulation by detecting mRNA in the nucleus of mouse stem cells differentiating to cardiomyocytes. We will develop fluorescent mRNA sensors that can be imaged in cells, based on near-IR fluorescent single-walled carbon nanotubes. Understanding mechanical cell regulation has far-ranging relevance for fundamental cell biophysics, developmental biology and for human health.";2425200;2425200;ERC-2013-ADG;/ERC-AG;GEORG-AUGUST-UNIVERSITAT GOTTINGENSTIFTUNG OFFENTLICHEN RECHTS;DE;;;"/PSE;/ELM;/NNT";1;0;0;1;0;0 188116;627936;FAIDA;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IEF;FP7;Feud and blood feud between customary law and legal process in medieval and early modern Europe. The case of the Upper-Adriatic area;2015-01-08;2017-12-08;;"Feud and blood feud are topics, which have been given a fair share of attention by researchers all over the world. The focus so far has been on anthropological research, based on collecting oral testimonies and less focus has been given to collecting various archival sources, which is a basic technique for interdisciplinary and interpretative studies of the social phenomenon mentioned and which should be correlated to general historical and civilizational development of society and law. The revenge itself is not merely protection of one's honor, which is also in contemporary society one of the pillars of the value of human dignity and represents a fundamental constitutional element of community as well as a social control and legal norm, which were developed and formed accordingly to development of society, culture and under the influence of the environment in which it was created. Therefore, the focus of the research project will be the area of Upper-Adriatic in the late Medieval and early Modern Age, due to area's unique intertwining of cultural, political and social impacts (influences of Greek, Roman, Slavic, Venetian, Habsburg and Ottoman culture), especially considering the interaction between urban and rural communities, their customs and legal norms. This signifies that the focus will be on comparative study of feud between customary law and (codified) legal process, i.e. the basis for the development of common law and civil law in countries under the influence of European justice culture. In this area, due to historical and environmental circumstances, customary law remained in practice and in the oral tradition, collected and recorded in the 19th and 20th century, which together with abundance of preserved archival material and legal documents, represents excellent starting point for the comparative studies of the development of law and general civilizational relations within this research field in Europe and in the World.";249242,8;249242,8;FP7-PEOPLE-2013-IEF;/MC-IEF;UNIVERSITA CA' FOSCARI VENEZIA;IT;;;;1;0;0;1;0;0 188130;628338;EMPTYSCAPES;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IEF;FP7;Filling ‘empty’ landscapes, mapping the archaeological continuum;2014-07-01;2016-06-30;;"The research proposal envisages a two-year interdisciplinary program designed to stimulate changes in the way in which archaeologists in Italy in particular but also more generally in the Mediterranean world study the archaeology of landscapes, moving from an essentially site-based approach to a truly landscape-scale perspective. The aim is to help in the development and wider application of new paradigms for landscape analysis based on the integration between ‘traditional’ approaches, multidisciplinary studies and new technologies in the form of large-scale geophysical survey and the collection and analysis of high-resolution LiDAR data. The geographical focus of the project will lie for the most part in central Italy (Tuscany and Lazio) where the candidate has been working on two sample areas. The objectives of the Marie Curie project can be summarized as follows: 1.To place the experience so far gained in Italy in a broader European and Mediterranean context through the review of information about relevant case studies elsewhere on the Continent and in the UK. 2.To continue and expand the fieldwork in central Italy, mainly filling gaps so as to achieve a more continuous picture of the areas under study by improving the size of the samples. 3.To confront and hopefully fill the gap between palaeo-environmental history and anthropic evidence by introducing environmental studies in the Italian context. 4.To focus on archaeological analysis and GIS-based interpretation in a multi-scale landscape context. 5.To improve understanding through the application of new technologies with particular regards to: a. Evaluating the influence on changing historical patterns across time. b. Improving understanding of the likely returns from different methodologies. c. Improving planning and conservation strategies and policies in Italy and in the Mediterranean area. 6.To learn from more advanced practice in the United Kingdom compared with the Mediterranean world.";309235,2;309235,2;FP7-PEOPLE-2013-IEF;/MC-IEF;THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;UK;;;;1;0;0;1;0;0 188066;626947;MOMEFAST;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IEF;FP7;Molecular Mechanisms Employed by the Newly Assigned RNA-binding Protein FASTKD2;2015-01-01;2016-12-31;;Posttranscriptional gene regulation is an essential process exerted by a multitude of RNA-binding proteins (RBPs) and allows for rapid adaptation of the cellular proteome to environmental perturbations. Previously, only in a limited number of instructive cases, the RNA networks targeted by individual RBPs had been elucidated. The recent proteome-wide unbiased identification of RBPs yielded a comprehensive catalogue of RBPs acting in human cells and has assigned an RNA-binding activity to over 300 orphan proteins, however without revealing their biological function. FASTKD (FAS-activated serine/threonine kinase domain-containing) proteins constitute an entire family of newly assigned RBPs with poorly defined functions and lack classical RNA binding domains. A loss of function mutation within FASTKD2 has been associated with a lethal form of infantile encephalomyopathy. FASTKD2 localizes to mitochondria and appears to regulate mitochondrial homeostasis by entirely undefined mechanisms. To address to which extent and how RNA binding contributes to the evidently vital functions of FASTKD2 I will extensively characterize the FASTKD2-RNA interface. I will determine the regions of FASTKD2 that interact with RNA making use of a novel and unprecedented technique termed RBDmap. The results of this analysis will guide systematic tests of RNA binding mutants of FASTKD2 in RNA interference based complementation assays. To obtain a comprehensive picture of the factors mediating the effects associated with a loss of function of FASTKD2 I will analyze the network of proteins and RNA motifs associating with FASTKD2 at the systems level. The models derived from the obtained data will be validated in cell-based assays. The required interdisciplinary approach is unique and will yield valuable insights into the molecular actions and interconnections of an entirely new type of RNA binding proteins in mitochondrial homeostasis in health and disease.;161968,8;161968,8;FP7-PEOPLE-2013-IEF;/MC-IEF;EUROPEAN MOLECULAR BIOLOGY LABORATORY;DE;;;;1;0;0;1;0;0 188119;628010;COLLABORATION;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IEF;FP7;Reducing the burden of offender mental illness in Europe: improving interorganisational collaboration between the mental health and criminal justice systems;2014-09-01;2016-08-31;;This fellowship enriches international research cooperation between Norway and UK with the long term goal of reducing the social and economic burden of offender mental ill health on the EU. High levels of mental illness in the offender population places financial and logistical burden on European prisons. This is attributable to professionals in mental health (MHS) and criminal justice systems (CJS) not collaborating effectively when offenders present with mental illness. Offender mental health would substantially improve if MHS/CJS professionals were better prepared for collaboration across organizational boundaries. There is currently no pedagogical framework available that supports this training need. The development of such a framework requires interdisciplinary approaches combining knowledge of interprofessional practice (IPP) with knowledge of interprofessional pedagogy. To date, research in interprofessional education (IPE) and IPP have coexisted with little overlap in their activity, meaning that there is a lack of IPE grounded in strong understanding of practice based issues, or substantiated by research into collaborative practice. Similarly, efforts to prepare a collaboratively ready workforce lacks understanding of sound interprofessional learning theory and education methods that better prepare staff for collaborative practice, This project addresses this by bringing together a talented researcher experienced in interprofessional pedagogy together with European leaders in interorganisational integration, collaborative practice and innovation. Their combined skills allow the development of a practice relevant and evidence based pedagogical framework to underpin training that prepares MHS and CJS professionals to work collaboratively in the interest of the mental health of the offender population. This pedagogical framework has transferability to other EU and clinical/welfare contexts where collaborative practice across organisations is required.;312491,6;312491,6;FP7-PEOPLE-2013-IEF;/MC-IEF;UNIVERSITETET I STAVANGER;NO;;;;1;0;0;1;0;0 188225;627769;BIOVALUE;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IEF;FP7;"Cultural and Bio - diversity Protection through Heritage Policies. Andean Potatoes’ Regimes of Value in Protected Areas and Beyond";2014-11-16;2017-03-08;;"Concerned by the global erosion of ecosystems, academic community and policy makers strive for implementing innovative policies towards a sustainable management of natural resources. These resources’ undervaluation is widely pointed out as a mayor hindrance to ecological conservation. It is therefore urgent to design accurate methods that acknowledge ecosystems’ pluridimensional value. The contribution of social scientists is necessary to take into account ecosystems’ symbolic and social values, along with economic and ecological ones. But, so far, anthropologists have not engaged with this urgent issue. The BIOVALUE project contributes to filling this gap in the scientific knowledge, by introducing a new methodological approach able to identify natural assets’ multiple valuation criteria. Heritage policies count among the more promising instruments for rising ecosystems’ multidimensional appraisal. The investigation also assesses heritage policies’ potential to effectively rise biodiversity’s value. On this purpose, the BIOVALUE project examines the FAO initiative for the conservation of Globally Important Agricultural Heritage Systems (GIAHS), focusing on the case of Andean potato farming (a fundamental bearer of the global agro-biodiversity). More precisely, ethnographic observation scrutinizes tubers’ “social biography” in order to reveal how their economic, ecological and social values vary as they travel through different economic spheres. Thereby, the research evaluates any production or destruction of values during heritagisation processes. At the crossroad of social and natural sciences, this investigation clusters an interdisciplinary team of scientists and articulates their expertise with international institutions involved in biodiversity and heritage preservation, thereby contributing to the development of participative global policies that safeguard both cultural and biological diversity.";183469,8;183469,8;FP7-PEOPLE-2013-IEF;/MC-IEF;WAGENINGEN UNIVERSITY;NL;;;;1;0;0;1;0;0 188171;629496;NEUROSTOCHSIM;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IEF;FP7;Neural Field Equations: Stochastic Approach and Numerical Simulations;2014-09-15;2015-09-14;http://www.math.tecnico.ulisboa.pt/~plima/neuro/;The aim of the present project is to provide the numerical modeling of neural processes, which can help to interpret the experimental data coming from EEG imaging. With this purpose we will use the Neural Field Equations (NFE), a widely used class of equations to model connected areas of neurons in the brain, in one to three dimensions. We emphasize on employing stochastic variants of NFEs to describe neural activity. We intend to develop new numerical methods and use them to carry out numerical simulations of the processes under investigation. We will test the results of our simulations by comparing them with the ones obtained by other methods in neuroscience, in particular data driven methods. The project includes in its final phase a collaboration with a research team working with medical data. The applicant, Pedro Lima (www.math.ist.utl.pt/~plima), is a member of the CEMAT (Center of Mathematics and Applications- www.cemat.ist.utl.pt), a research unit of the Instituto Superior Técnico (www.ist.utl.pt ), which is part of the Technical University of Lisbon (www.utl.pt). He will visit for one year the Johannes Kepler Univesity (JKU- www.jku.at ) at Linz, where he will work at the Institute of Stochastics ( www.jku.at/stochastik) , under the direction of Prof. Evelyn Buckwar (the leader of the Institute).The main training objective of the applicant is the development of expertise in Stochastic Numerical Analysis, Modelling with NFEs and Mathematical Neuroscience. He will benefit from the excellent experience of the research team of the Institute of Stochastics of the JKU, which is renowned for its interdisciplinary strengths and track record on applied mathematical modeling. This project will have a very significant impact in the career of the applicant, giving him skills that will enable him to participate in multidisciplinary projects in the field of neuroscience. In this way he will reinforce a position of professional maturity.;124189,8;124189,8;FP7-PEOPLE-2013-IEF;/MC-IEF;UNIVERSITAT LINZ;AT;;;;1;0;0;1;0;0 188170;629486;GOTH-NAR-HAITIAN-REV;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IEF;FP7;Transatlantic Politics of Horror and Terror in Gothic Narratives of the Haitian Revolution, 1791-2011;2014-04-01;2016-03-31;;"Silenced in hegemonic historiography, the Haitian Revolution (1791-1804) was one of the key transformations of the Age of Revolution. As the first & only successful slave revolution & one of the first anti-colonial revolutions in modern history, it has mounted multiple challenges to the transatlantic colonial economy and hegemonic North Atlantic ideologies which continue to assume the cultural superiority of Europe & the USA. Through their double act of revolutionary self-emancipation from slavery and colonialism, the Afro-Caribbean slaves radicalised both the French Revolution & the European Enlightenment. For they challenged & extended the limited scope of Rights of Man as they exposed & removed its race and class limitations: a milestone towards universal human rights. The interdisciplinary project aligns itself theoretically with (re)-appraisal of the centrality of the Haitian Revolution to transatlantic history and modernity, as it is displayed in the recent ‘Haitian Turn’ in transatlantic studies & by earlier radical black theorists and activist. It will trace the genealogy of the ‘Haitian Gothic’ in the transatlantic discourse from 1791 to the present. It understands it as a broader, powerful rhetorical-political mode that operates across a wide range of medial genres (literature, political articles, pamphlets, histories, visual representations e.g. caricatures & films). Its working hypothesis posits that the continuing ‘gothicisation’ of Haiti, its history & its people forms a reaction to the profound challenges that HR has posed to the hegemonic transatlantic political, economic and ideological (neo)-colonial order. It distinguishes between the ‘hegemonic Haitian Gothic’ that demonises Haiti & its revolution & the ‘radical Haitian Gothic’ that appropriates the Gothic to extol the radically emancipatory nature of the Haitian Revolution. UCLAN with its world-class researchers in transatlantic studies (e.g. Prof. Rice) provides an ideal host institution.";299558,4;299558,4;FP7-PEOPLE-2013-IEF;/MC-IEF;UNIVERSITY OF CENTRAL LANCASHIRE;UK;;;;1;0;0;1;0;0 188092;627200;PaGaNS;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IEF;FP7;Plotinus against Gnostics: a New Survey;2015-07-01;2017-06-30;;"The PaGaNS project aims to prepare, in 2 years, a new constitution of the text and a new thorough philological commentary to three Plotinian anti-Gnostic treatises (III.8 [30], V.8 [31], V.5 [32]). Since the philological research on Plotinus’ works has been neglected after Henry – Schwyzer’s ed. minor (1982), there is still much scope for philological analysis in the Enneads. It is unavoidable to examine the sources for the reconstruction of Gnostic thought and Plotinus’ polemic fight, e.g. the Nag-Hammadi Coptic texts. Moreover, these three treatises (together with tr. II.9 [33], the critical text and commentary of which have already been prepared) have often been considered part of a single essay (the so-called Großschrift), a suggestion that has found many opponents and certainly needs a fresh analysis. The PaGaNS project will be carried out this way: 1) new collation of the medieval manuscripts; 2) philological analysis of the text; 3) new examination of H.-S.’ textual choices; 4) preparation of a philological commentary explaining all editorial choices and proposing new solutions for all textual issues; 5) new examination of the Großschrift theory; 6) new examination of all Gnostic sources (e.g. the Nag-Hammadi rolls, Irenaeus). PaGaNS project’s outcomes will be two Belles Lettres volumes (Collection Budé, C.U.F), which are intended to be part of a new edition of the entire Plotinian corpus, an international project called Projet Plotin, conceived and led by Prof. J.-M. Narbonne (Univ. Laval, Québec, CA). This multidisciplinary/interdisciplinary project aims to create a research network including all Projet Plotin centers (located in Canada, USA, Brazil, Italy) and the CNRS (part., the Centre Jean Pépin/UPR 76), French host of the project. The PaGaNS project also aims to provide ERA with a deeper understanding of Plotinus’ thought and of the 3rd century cultural/religious background to the history of Christianity and to the birth of the idea of Europe itself.";202405,8;202405,8;FP7-PEOPLE-2013-IEF;/MC-IEF;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FR;;;;1;0;0;1;0;0 188038;626664;RECLAIM;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IEF;FP7;The Legitimacy of Mutual Recognition as a Regulatory Strategy for the Policy Area of Civil Justice in the EU;2014-09-01;2016-08-31;;The research will focus on the principle of mutual recognition and the therewith presumed mutual trust between courts in the policy area of EU civil justice. The principle of mutual recognition, held to be the cornerstone of civil justice, has been transposed from its traditional Internal Market context to this novel policy arena. This transposition raises the question of how the economic and other goals of free movement can be reconciled with due process and access to justice. The research will seek to explore this question in light of the growing body of enacted legislation and case law in the field of civil justice as well as other recent developments. The research will seek to assess whether the various underlying goals are compatible. The research will also seek to assess whether the various overarching measures, including networks and e-justice tools, sufficiently support mutual recognition or whether concerted action in the field of judicial training will come to be seen as necessary. Finally, the research will explore whether mutual recognition is sufficient or whether pressures for further harmonization of civil procedure are emerging. The ensuing responses will fundamentally impact on the perception of the legitimacy of civil justice. The research will be interdisciplinary. First, in exploring the challenges of mutual recognition relevant comparisons will be made to the traditional internal market context and theoretical framework but in particular to the developments in the EU criminal justice field. Secondly, the research will in the discussion on legitimacy seek a dialogue also with the political science debate on the legitimacy of European integration in the Area of Justice, Freedom and Security and on access to justice in an ever globalized world.;197811,6;197811,6;FP7-PEOPLE-2013-IEF;/MC-IEF;UPPSALA UNIVERSITET;SE;;;;1;0;0;1;0;0 188476;336355;MicroDE;ONG;FP7-IDEAS-ERC;ERC-SG-LS9;FP7;Interpreting the irrecoverable microbiota in digestive ecosystems;2014-02-01;2019-01-31;;"Currently available enzyme technology is insufficient to economically degrade plant biomass, and presumably will remain so whilst fundamental questions are inadequately answered, the most evident being: “how do microbes and their enzymes interact with plant cell walls?” Compounding these difficulties is the “cultivability bottleneck”. The microbes that harbor the answers to these questions are largely irrecoverable in isolate form, which restricts access to their genetic and metabolic machinery. The present project will address these issues by applying a progressive interdisciplinary approach to study and compare natural and engineered digestive ecosystems that are linked together via overlapping phenotypic and functional traits (i.e. biomass degradation). The project aims to generate insight into diverse uncultured microbial lineages and uncover core enzyme systems for biomass degradation that are present in multiple environments. To achieve its objectives the project will employ a combination of predictive genome-reconstruction technologies, as well as metagenome-directed isolation strategies to target dominant and novel saccharolytic species. Furthermore we will develop and take advantage of advanced software for enzyme annotation and phylogenetic binning as it is being developed. Relevant genes identified from reconstructed genomes and/or transcriptome data for isolates will be cloned, over-expressed and their gene products tested using state-of-the-art carbohydrate microarray technologies, prior to being characterized in detail. The project will complement existing activities at the PI’s university on (1) polysaccharide converting enzymes in a biorefining context, (2) the impact of intestinal fiber deconstruction on satiety and (3) enhanced production of biogas. We expect to unravel novel aspects of the microbial ecology within these systems/processes. Furthermore, it is envisaged that novel isolates and enzymes will enter into live bioenergy projects.";1467175,6;1467175,6;ERC-2013-StG;/ERC-SG;NORGES MILJO-OG BIOVITENSKAPLIGE UNIVERSITET;NO;;;"/ABI;/BIO;/LIF;/MED;/MBI";1;0;0;1;0;0 187970;625889;YOUTH ENTREPRENEURS;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IEF;FP7;Youth Entrepreneurship in Portugal and the UK;2014-11-01;2016-10-31;;"Promoting youth entrepreneurship has become a crucial EU strategy in addressing high unemployment rates. Statistics have indicated that, although young people show interest in starting up ventures, there is a big gap between intentions and concretization. Additionally, entrepreneurial intentions/activities seem to vary largely across European countries. Research on determinants of entrepreneurship has focused mainly in macro-economic and individual level factors. The analysis of entrepreneurship in cultural terms has remained elusive. Thus, the main aim of the Youth Entrepreneurs proposal is to also explore cultural/contextual factors associated with fostering/challenging youth entrepreneurship. More precisely, it is intended to: 1) analyse and compare the experiences and characteristics of youth entrepreneurship in two economically and culturally distinct European countries (Portugal and UK); 2) to apply a distinctive participatory approach that will engage young people and stakeholders in the research process; 3) implement outreach activities designed to maximise impact of the findings. Using an interdisciplinary team, this project aims to bring together insights from psychology, geography/sociology and business studies. It will be applied an innovative mixed and comparative methodology, combining quantitative, qualitative (e.g. focus-groups, semi-structured interviews and biographical narrative interviews), and participatory (e.g. workshops) approaches. The results of the project will provide comprehensive knowledge about different types of factors (e.g. familiar, financial) influencing entrepreneurship, and outline support policies that better match the real needs of young people in each country. This project will be carried out in Keele University, which has strong expertise in comparative and mixed method approaches. Prof. Clare Holdsworth is the scientist-in-charge. She is an internationally recognized scholar with particular expertise in youth transitions";299558,4;299558,4;FP7-PEOPLE-2013-IEF;/MC-IEF;UNIVERSITY OF KEELE;UK;;;;1;0;0;1;0;0 187867;624675;KMLIEGROUPS;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IEF;FP7;Infinite-dimensional Lie theory and Kac-Moody groups;2014-10-01;2016-09-30;;"'Lie theory was created at the end of the 19th century, and rapidly became a central chapter of contemporary mathematics. Finite-dimensional Lie groups and Lie algebras were extensively studied for more than a century, and are well understood. In attempting to generalise the finite-dimensional objects, one can roughly distinguish two general approaches, one 'analytic' (keeping the smooth manifold structure of Lie groups) and the other “algebraic” (which is best represented by the algebraic constructions of Kac-Moody groups). Although intensively studied, Kac–Moody groups and Lie groups beyond the affine case remain mysterious to a large extent, and many questions concerning their structure remain open. In my Ph.-D. thesis, I established several structure results concerning topological Kac–Moody groups of indefinite type, and part of this research project carries on this study further. The main goal of this research project is to get a better understanding of Kac–Moody groups beyond the affine case, from both the analytic and algebraic approaches, and to try to construct “concrete realisations” of these groups (at least for hyperbolic types), by studying the unitary representations of their Lie algebra. More precisely, my method would be to try to construct certain “concrete” representations of a distinguished class of Lie algebras that include all symmetrisable Kac–Moody algebras; it should then be possible to construct “concrete realisations” of the corresponding groups by integrating these representations, hopefully allowing for an in-depth study of these groups. This research project would allow me to significantly broaden and diversify my mathematical knowledge and experience, as I would study Kac-Moody groups and algebras from a wholly different perspective (the 'analytic' one) and investigate its applications to theoretical physics, thus placing my research in an interdisciplinary context.'";168794,4;168794,4;FP7-PEOPLE-2013-IEF;/MC-IEF;FRIEDRICH-ALEXANDER-UNIVERSITAET ERLANGEN NUERNBERG;DE;;;;1;0;0;1;0;0 188024;626519;UVTRANCYCLUM;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IEF;FP7;Molecular characterization of environmental stress responses in the marine diatom Phaeodactylum tricornutum;2015-01-01;2016-12-31;;Solar UV-B radiations can have a negative impact on photosynthetic organisms leading to a reduction of the uptake of atmospheric carbon dioxide. Aquatic ecosystems absorb a similar amount of atmospheric carbon dioxide as terrestrial ecosystems, are estimated to produce half of the biomass on our planet and are a major source for human food supply. At the base of these ecosystems, phytoplankton are the main primary producers. Among them, diatoms have colonized all types of aquatic environments and are thought to be responsible for as much as 20 % of global primary productivity. Although diatoms do not have the plant UV-B photoreceptor (UVR8), they are able to accumulate UV-B absorbing compounds when exposed to UV-B, suggesting adaptive responses. However, when exposed to chronic UV-B exposure, diatoms exhibit a decreased growth rate and increased cell volume reflecting a decoupling between cell division and cell growth. The proposed project aims at defining the genetic basis of systemic and specific signaling pathways in response to UV-B in the diatom Phaeodactylum tricornutum. A high throughput approach will be used to unveil the transcriptomic reprogramming happening upon UV-B stress. DNA stress checkpoint and DNA repair genes will be further characterized for their response to UV-B as the encoded proteins are essential actors at the interface of environmental stress and the controlling of cell cycle blockage and re-entrance. Promoters of the highly UV-B regulated genes will be dissected to identify cis-elements and further used to identify potential UV-B specific transcription factors. The project aims at integrating my knowledge on light signaling in the cell cycle research work on diatoms performed in the group of Prof. Lieven De Veylder. Exploration of this novel interdisciplinary scientific niche, together with the acquisition of new knowledge and additional skills, will help me in obtaining a position as an independent researcher in the near future.;177000;177000;FP7-PEOPLE-2013-IEF;/MC-IEF;VIB;BE;;;;1;0;0;1;0;0 187998;626248;YUGOSLAVIA REVISITED;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IEF;FP7;Yugoslavia Revisited: Post-Yugoslav Literature and Art as Curators of the Socialist Past;2015-02-01;2017-01-31;;"This interdisciplinary project aims to investigate how post-Yugoslav literature and art remembers the heydays of socialist Yugoslavia (1950s-1970s) and how these acts of remembrance critically intervene in the public sphere. Focusing on a number of selected cases from prose fiction, film, visual art and performance/theater, the project will not only scrutinize how the arts ‘archive’, ‘document’ or ‘recall’ the everyday life and memory of socialist Yugoslavia, but also examine how critical cultural practices and the memories they mediate help envision a better future and open up new avenues to cosmopolitanism. Utilizing a dynamic understanding of cultural memory as a performative engagement with the past, this project will center on the following questions: (1) How do post-Yugoslav artistic practices act as curators of the socialist past in opposition to the dominant ideologies of nationalism and neoliberalism? (2) How does post-Yugoslav literature and art acknowledge the mediated character of memory? (3) How do the ways in which the arts shape and circulate the cultural memory of Yugoslavia help transcend national and ethnic boundaries and imagine new forms of solidarity? (4) How do literature and art deal with the issue of Europe and transnational identity, and how is this reflected in their reception? The cultural memory of the multinational socialist Yugoslavia, of its utopian potential as well as of its violent breakdown, has broad repercussions that strongly resonates with the endeavor of the European Union to create a shared European identity based on a common understanding of the (European) past. By providing an analysis of post-Yugoslav artistic practices of cultural remembering, the project will produce new knowledge on this specific case, provide a theoretical contribution to cultural memory studies, and contribute to broader current debates on a common European cultural memory and transnational identity.";183469,8;183469,8;FP7-PEOPLE-2013-IEF;/MC-IEF;UNIVERSITEIT UTRECHT;NL;;;;1;0;0;1;0;0 187852;624453;ALPHA-BRAIN-IMAGING;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IEF;FP7;"Brain image processing with Alpha-Stable distributions. Applications to intensity normalization, segmentation and diagnosis of Parkinsonian syndrome and Alzheimer's disease";2014-07-16;2017-05-03;;"In this project, D. Salas-Gonzalez proposes to develop brain image processing with alpha-stable distributions with applications to intensity normalization, segmentation and diagnosis of Parkinsonian syndrome and Alzheimer's disease. The expected results of this interdisciplinary project will definitely have applications and impact in the European society and its health, which is an objective of the '2020 Vision for the European Research Area’. Specifically, Parkinson’s disease and Alzheimer type dementia are a research priority in developed countries, as their population is becoming older and, therefore, there will be more prevalence of these neurodegenerative diseases in the future. The main goal and overall objective of this project is to attract the attention of neuroimaging experts to the potentialities and wide range of applications of the alpha-stable distribution: a heavy-tailed, non-symmetric distribution with similar desirable properties to the Gaussian density. The Gaussian distribution is used ubiquitously in neuroimaging. For this reason, the alpha-stable density can be potentially used as an alternative to the Gaussian distribution. In addition, in order to show the wide range of application in neuroimaging of the alpha-stable distribution, four different research objectives are envisaged in this project. They include basic research, strategic research, applied research and transfer of knowledge: i) Intensity normalization of FP-CIT Single Photon Emission Computerized Tomography brain images. ii) Segmentation of Magnetic Resonance Images (MRI). iii) Feature extraction for Parkinsonian syndrome diagnosis. iv) Feature extraction for Alzheimer's disease diagnosis. v) Software implementation for real applications.";223778,4;223778,4;FP7-PEOPLE-2013-IEF;/MC-IEF;UNIVERSITAET REGENSBURG;DE;;;;1;0;0;1;0;0 187013;631610;GrabFast;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-CIG;FP7;Graphene Based Ultrafast Lasers;2014-03-01;2018-02-28;;"Manipulating structure and composition in the nanoscale allows the creation of novel materials with superior performance for new products and devices. The introduction of a wide range of new low-cost nanomaterials is expected to have a disruptive impact on a variety of conventional inorganic semiconductor devices, not only because of performance/cost advantages, but also because they can be manufactured in more flexible ways, suitable for a growing range of applications. Graphene, a single layer of carbon allotrope, exhibits extraordinary optical and optoelectronic properties for ultrafast broadband photonics, including ultrafast response, high mobility, broadband absorption, and gate-variable optical conductivity, in addition to flexibility, robustness and environmental stability. My proposal aims to use graphene to create a new range of ultrafast lasers, such as ultrafast fiber, solid-state, and waveguide lasers. These lasers will break the spectrum and speed bottleneck of existing devices, and thus can provide cost-effective, energy-saving and robust tools with unprecedented speed and bandwidth, ideally fitting a large range of growing and emerging applications, such as high-speed telecommunication, industrial material processing, metrology, medicine and sensing applications. This is an ambitious frontier research program, with a strong interdisciplinary nature, across Engineering, Physics, Chemistry and Matter sciences.";100000;100000;FP7-PEOPLE-2013-CIG;/MC-CIG;AALTO KORKEAKOULUSAATIO SR;FI;;;/LIF;1;0;0;1;0;0 189954;627630;PEROXIREDOXIN-CLOCK;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IEF;FP7;A new intracellular metabolic timer mechanism to induce cell death selectively in cancer cells;2014-08-04;2016-08-03;;"Peroxiredoxins (PRX) are at the heart of mechanisms gating the spatiotemporal distribution of ROS molecules within the cell and thereby deeply involved in the development or progression of disease. With the host group’s recent discovery on the circadian nature of PRX-hyperoxidation cycles, PRXs emerge to be tested for driving the physiological 24 h periodic fluctuations of the cellular redox state and ROS-signaling, both being critical in cell cycle control. The potential of the PRX-clock to robustly orchestrate cell cycle progression or apoptotic pathways will be analyzed in the proposed multidisciplinary study. The working hypothesis of the project is that this new timing mechanism operates even in rapidly proliferating cells and that it can be manipulated to deteriorate cancer cell survival selectively. Identification of new ROS-regulated targets promoting apoptosis specifically in transformed cells will have a huge impact on cancer therapy. At the host Institute in Cambridge, U.K., the Fellow will reveal post-transcriptionally regulated targets of PRX and their involvement in ROS-signaling and apoptosis induction in cancer. Through this project he will be able to address hot scientific issues and do important science in the future; furthermore, he will learn many new creative ways of thinking applied by world-renowned researchers in Cambridge. Know-how acquired during this training will open new intersectoral dimensions (Cell cycle biology, ROS biology) for the Fellow, and the evaluation of data obtained during the project will strengthen his interdisciplinary way of thinking.";231283,2;231283,2;FP7-PEOPLE-2013-IEF;/MC-IEF;THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;UK;;;;1;0;0;1;0;0 189899;623747;IRELLAS;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IEF;FP7;The Greek Connection: Irish Poets and Contemporary Greece;2015-02-20;2016-02-19;;"The project traces down the connections between two Irish poets – Seamus Heaney and Derek Mahon – and contemporary Greece. Its interdisciplinary and intersectoral character resides in its methodology and scope of themes. Methodology of the project involves: comparative literature (work of Irish and Greek Nobelists: Heaney, Seferis, Elytis; and Derek Mahon); ecocriticism (landscapes, environmental concerns); translation studies (comparative analysis of translation projects launched by Mahon, Seferis and Elytis, who incorporated these 'transcriptions' into their own literary output); postcolonial studies (status of language and culture in both countries historically and politically dominated by foreign powers); reception theory (fertile readings and misreadings of Greek literature by Irish poets). The scope of themes ranges from ecology (environment pollution, social and industrial ecology, including a new subject of pollution by tourism), social change and mobility (emigration, globalization, interethnic relations), cultural linguistics (historical traces in language, its politicization), cultural studies (memory, heritage, identities, ethics, diversity), through history (including colonial, military, cultural history of both countries), archaeology, to anthropology (myths, tropes). The objectives of the project will be achieved via research at the University of Athens, series of conferences, publications, repository articles, research visits to Ireland, and finally, a book. The results will be also spread online and via meetings with students and general public. Discussing the relations between Irish and Modern Greek literature is completely innovative; thus, through its originality, the project thus contributes to the development of the European research area. The project constitutes a stage in the progress of the researcher's career, leading to the achievement of an independent research position (professorship).";111889,2;111889,2;FP7-PEOPLE-2013-IEF;/MC-IEF;ETHNIKO KAI KAPODISTRIAKO PANEPISTIMIO ATHINON;EL;;;;1;0;0;1;0;0 192371;339239;REWARD;ONG;FP7-IDEAS-ERC;ERC-AG-SH2;FP7;Performance-based Innovation Rewards;2014-02-01;2019-01-31;;"REWARD will open up new horizons in complementing the international intellectual property rights (IPR) system. The project's ambitious output is an ethically and legally sound performance-based reward mechanism for pharmaceutical innovation, which complements the existing patent regime, yet mitigates its considerable disadvantages for the global poor. The current IPR system impedes access to life-saving medicines for the poor in two main ways. First, high prices for pharmaceutical innovations are required to recoup research and development costs through time-limited patent protection. Whilst high price levels maintain incentives for pharmaceutical innovation, they price new medicines beyond the range of the poor creating an accessibility problem. At the same time, diseases that burden the poor are often not worthy of investment for pharmaceutical innovators, creating an availability problem ('neglected diseases'). Many international research groups are working on IPR reform plans based on performance-based rewards for pharmaceutical innovation. However, their efforts are disparate and lacking a guiding vision. REWARD will use world-class ethics research as the steering force to determine which performance-based reward mechanism for pharmaceutical innovation is the most promising. In an interdisciplinary collaboration of ethicists, lawyers, economists, and statisticians, with experts in medicine, science and technology policy and gender studies the selected mechanism will be tested in a developed and a developing country.";1922338,4;1922338,4;ERC-2013-ADG;/ERC-AG;UNIVERSITY OF CENTRAL LANCASHIRE;UK;"RESEARCH AND INFORMATION SYSTEM FOR DEVELOPING COUNTRIES;University of Calgary";"IN;CA";/SOC;1;0;0;1;0;0 192380;340055;METBIOCAT;ONG;FP7-IDEAS-ERC;ERC-AG-PE5;FP7;Metal catalysis in biological habitats: New strategies for optical bio-sensing and targeted therapy;2014-02-01;2020-01-31;;"This proposal aims at the discovery of robust transition-metal catalyzed transformations that can take place in aqueous media and cellular lysates, and are susceptible of being exported to living cells. Specifically, we will exploit the special coordination and activation ability of different metal complexes towards pi-systems to induce chemo-selective reactions of designed, abiotic, unsaturated substrates. Moreover, and importantly, the metal catalysts will be conjugated to designed ligands or biopolymers so that the catalytic power of the metal complex can be transferred to specific “in vivo” locations. Initial designs in this latter “high risk” endeavor will be guided by the current knowledge on metal-catalyzed bio-orthogonal chemistry as well as by some precedents on catalysis-based metal-sensing tactics. Ultimately, we want to install catalytic power in specific cellular sites and/or endow catalytic properties to any selected bio-molecular target. The catalytic activity could then be used to trigger the amplified generation of fluorescent signals or boost the production of bioactive drugs from inert, non-toxic precursors. This will set the basis for the development of efficient bio-sensing and imaging tools, and “in cellulo” diagnosis tactics, and of novel target-directed therapeutic strategies. With the crescent identification of disease-related biomarkers, the development of biomarker-associated diagnosis and therapy protocols is becoming one of the more urgent challenges in modern life sciences. Advances in early diagnosis can have a profound impact in public health, and boost new technology developments. The transversal expertise of my group in synthesis, metal catalysis, molecular recognition and chemical biology (see PI profile) places us in a rather unique position to tackle this type of interdisciplinary project.";2356276;2356276;ERC-2013-ADG;/ERC-AG;UNIVERSIDAD DE SANTIAGO DE COMPOSTELA;ES;;;"/PSE;/MAT;/IND";1;0;0;1;0;0 192360;335607;Emotions in Conflict;ONG;FP7-IDEAS-ERC;ERC-SG-SH4;FP7;Direct and Indirect Emotion Regulation as a New Path of Conflict Resolution;2014-02-01;2019-01-31;;"Intractable conflicts are one of the gravest challenges to both humanity and science. These conflicts are initiated and perpetuated by people; therefore changing people's hearts and minds constitutes a huge step towards resolution. Research on emotions in conflicts has led to the realization that intergroup emotions are critical to conflict dynamics. This project’s intrinsic question is whether and how intergroup emotions can be regulated to alter attitudes and behavior towards peace. I offer an innovative path, using two strategies of emotion regulation. The first is Direct Emotion Regulation, where traditional, effective emotion regulation strategies can be used to change intergroup emotional experiences and subsequently political positions in conflict situations. The second, Indirect Emotion Regulation, serves to implicitly alter concrete cognitive appraisals, thus changing attitudes by changing discrete emotions. This is the first attempt ever to integrate psychological aggregated knowledge on emotion regulation with conflict resolution. I propose 16 studies, conducted in the context of the intractable Israeli-Palestinian conflict. Seven studies will focus on direct emotion regulation, reducing intergroup anger and hatred, while 9 studies will focus on indirect regulation, aspiring to reduce fear and despair. In both paths, correlational and in-lab experimental studies will be used to refine adequate strategies of down regulating destructive emotions, the results of which will be used to develop innovative, theory-driven education and media interventions that will be tested utilizing wide scale experience sampling methodology. This project aspires to bridge the gap between basic and applied science, creating a pioneering, interdisciplinary framework which contributes to existing knowledge on emotion regulation in conflict and implements ways to apply it in real-world circumstances.";1499343,6;1499343,6;ERC-2013-StG;/ERC-SG;INTERDISCIPLINARY CENTER (IDC) HERZLIYA;IL;;;/SOC;1;0;0;1;0;0 188510;340956;IOW;ONG;FP7-IDEAS-ERC;ERC-AG-SH2;FP7;"""The Individualisation of War: Reconfiguring the Ethics, Law, and Politics of Armed Conflict""";2014-05-01;2019-04-30;;"'This path-breaking interdisciplinary project critically analyses the impact of the increased prominence of the individual in the theory and practice of armed conflict. The ‘individualisation of war’, while based on powerful normative and technological developments, places enormous strain on the actors most actively engaged in contexts of conflict: the governments and armed forces of states, international security organisations, and humanitarian agencies. Individualisation has generated new kinds of ‘humanitarian’ wars and peacekeeping missions, as well as precision weapons which enable both the targeted killing of those individuals deemed most liable for acts of war or terror, and the protection of innocent civilians caught up in armed conflict or acts of state suppression. It has also facilitated the injection of human rights law into the law of armed conflict, and a new class of international crimes for which individuals can be held accountable. We hypothesise that efforts to operationalise protection, liability, and accountability are all underpinned by a tension between the newly privileged moral and legal claims of individuals and the more traditional ones of sovereign states. The ethical, legal, and political dilemmas raised by these efforts demonstrate just how contested the process of individualisation remains, and how uncertain is its eventual endpoint. The research of our distinguished inter-disciplinary team will produce two main outcomes: the first integrated conceptual framework for explaining and resolving the dilemmas raised by the individualisation of war; and concrete recommendations for policy actors - both on how to respond to particular ethical, legal, or political challenges and on how to shape the longer term trajectory of individualisation.'";2397577;2397577;ERC-2013-ADG;/ERC-AG;EUROPEAN UNIVERSITY INSTITUTE;IT;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;UK;/SOC;1;0;0;1;0;0 187654;621724;OPERADYNADUAL;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IEF;FP7;Operator algebras and single operators via dynamical properties of dual objects;2014-10-01;2016-09-30;;"The project lies at the intersection of operator algebras, operator theory and dynamical systems, with elements of experimental mathematics and applications to noncommutative structures, completely positive dynamics, spectral analysis of functional operators, and potentially to the theory of functional-differential equations and quantum physics. It is centered around a development of an innovative powerful mathematical apparatus based on a construction of objects (of both dynamical and combinatorial nature) dual to semigroups of C*-correspondences over generically noncommutative algebras. This will allow a detailed analysis, of vast class of objects defined in terms of generators and relations, inaccessible through the existing methods. This specifically concerns algebras arising recently in connection with number and ring theory, thermodynamical phenomena, quantum spaces, quantum field theory and many more. The envisaged applications are broadly related to the analysis of quantum structures and evolutions of systems modeling complicated physical processes containing both dynamical contributory factors and interaction with outer media, e.g. the process of motion and transformation of particles. The asymptotic and ergodic properties of such systems are described by spectral properties of the appropriate operators. A substantial contribution to the theory of the latter on the basis of the elaborated general results and scientific computing is expected to be achieved. The project will integrate the fellow with an excellent Scandinavian scientific network of world leaders in crossing the boundaries between operator algebras and other fields. It will also allow cooperation with a number of visiting experts from outside the ERA. The research outputs and developed innovative methods of analysis will bring to the ERA a unique expertise of great impact and scientific value, with a wide range of potential interdisciplinary applications.";308587,8;308587,8;FP7-PEOPLE-2013-IEF;/MC-IEF;SYDDANSK UNIVERSITET;DK;;;;1;0;0;1;0;0 187723;622882;VIFER;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IEF;FP7;The Visual Front-End of Reading;2014-10-01;2016-09-30;;This research proposal aims at deepening the understanding of one fundamental issue of human cognition – how the perceptual fluency associated with skilled word reading is learned – and in doing so will provide for the first time a comprehensive learned neurocomputational account of printed word perception. The issue is of extreme general interest because it regards the establishment of one ontogenetic humanity achievement, symbolic language communication, on the top of cortical structures evolved to support phylogenetic cognitive functions. The subject is highly interdisciplinary, encapsulating visual perception and lexical processing, typically addressed separately in computational modeling. Indeed, the lack of an integral account undermines established theoretical models and related research. Assuming raw visual input and self-organization in deep generative networks, our model will be the first to provide a comprehensive account of the development of the known gradient of visual-lexical processing along the left occipitotemporal cortex. With the help of a novel electrophysiological method, we will collect neural signatures of various processing stages and fit the emergent hierarchical structure. Importantly, the learned model will allow us to study typical and atypical developmental paths of reading. In sum, the project will deepen the understanding of a very broad range of language-specific and general cognitive phenomena, and will open the way for a comprehensive neurocomputational account of all aspects of language processing. The Experienced Researcher will deepen his theoretical knowledge, master his expertise in neurocomputational modeling and gain proficiency in electrophysiological methods at the Host institution, a top research institution in the field. The training-trough-research will boost the professional maturity and career development of the Experienced Researcher to the point of complete research independence translatable to a permanent position.;269743,8;269743,8;FP7-PEOPLE-2013-IEF;/MC-IEF;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FR;;;;1;0;0;1;0;0 187713;622786;PROVISIONE;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IEF;FP7;Quality of vision and subjective satisfaction in new non-spectacle systems for restoring accommodation in presbyopic people;2015-03-02;2017-03-01;;"ProVisione project offers to the Researcher an extraordinary opportunity to become an independent scientist in the field of vision sciences. The Researcher’s interest in studying the quality of vision in patient with different systems of optical correction finds in the project the perfect ground in which acquire new skills and knowledge. The topic of the project is the correction of presbyopia, that is the physiological, age-related loss in near visual function associated with the loss in accommodation. There is a huge interest in the field because presbyopia prevalence is extremely high with the number of presbyopes that in 2005 exceed one billion. Moreover there is increasing demand of presbyopia non-spectacle correction. ProVisionet will bring different, interdisciplinary expertise together in order to study the relationship between two new optical approaches to restore accommodation (the Scleral surgery and the Femtosecond Laser to treat the lens), the visual outcomes and patient satisfaction. Effectiveness will be evaluated longitudinally and compared to other non spectacle, pseudo-accommodative optical devices available for presbyiopic correction (monovision and multifocal Contact Lenses, multifocal and accommodative Intraocular Lenses). The objective of the project will have to cover different areas that represent research pillars: optical devices used in the project, optical quality of the eye and accommodative response, psychophysics of visual function, subjective quality of vision, perceptual factors that affect the quality of vision. This will be possible thanks to the expertise from 3 Universities (the Host University in UK, one in Italy and one in Germany respectively), 3 Clinical Structures (2 Private clinics in UK and Italy; 1 NHS clinic in UK), 2 private companies (Germany and Italy). ProVisione will involve a series of prospective and retrospective clinical studies that will be carried out on presbyopic patients from the clinical centres involved";231283,2;231283,2;FP7-PEOPLE-2013-IEF;/MC-IEF;ASTON UNIVERSITY;UK;;;;1;0;0;1;0;0 187720;622867;UCDVERITAS;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IEF;FP7;Indirect Search for Dark Matter Using the VERITAS Telescope Array;2015-02-09;2017-02-08;;Observations of the motions of stars and galaxies in large-scale structures have revealed that most (>80%) of the matter in the Universe is invisible. The nature of the “dark matter” is one of the outstanding puzzles in modern physics and experiments are underway to detect and characterize it. There are three main experimental approaches: direct detection of dark matter particles arriving from space, generation and detection of dark matter particles in particle accelerators, and indirect detection via observation of the gamma rays produced when dark matter particles decay or self-annihilate. Such gamma rays would travel from sites of dark matter density in the universe, and be observable on Earth with gamma-ray telescopes. My research proposal is to utilize very-high-energy (VHE) gamma-ray observations of candidate astrophysical dark matter sites to measure or constrain the dark matter annihilation rate, and to statistically combine the results with those from collider and other VHE telescope searches. The research will utilize VERITAS, one of the leading VHE gamma-ray observatories currently in operation, and will be conducted under the supervision of Dr. John Quinn at University College Dublin. A key component of the research will be to investigate improved analysis techniques to enhance the gamma-ray selection and background rejection image analysis techniques employed in the analysis of VERITAS data. I developed expertise with these methods during my graduate and post-doctoral work in particle physics, and am thus uniquely positioned to adapt and refine such techniques for use in astrophysics. I will also combine gamma-ray annihilation rate limits with complementary measurements from other telescopes and collider experiments to produce significantly improved constraints on dark matter. This project is highly interdisciplinary, bringing together particle physics and astrophysics with image processing, multivariate data analysis and statistical techniques.;191359,8;191359,8;FP7-PEOPLE-2013-IEF;/MC-IEF;UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN;IE;;;;1;0;0;1;0;0 187671;622114;CAND;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IEF;FP7;Collective Attitudes and Normative Disagreement;2014-10-01;2016-09-30;;"CAND - Collective Attitudes and Normative Disagreement concerns the perspectival nature of legal discourse. The main aim of the project is to increase our understanding of legal and normative discourse in light of contemporary accounts of the semantics and pragmatics of deontic modals, and of collective intentionality. This is a highly interdisciplinary project, connecting various philosophical disciplines with jurisprudence. The project will apply state-of-the-art theories and arguments of contextualist semantics about deontic modals and value predicates to the case of statements of law (i.e. statements of what, according to law, one ought to do). This will be achieved by a systematic exploration of the relationship between four debates in four different areas: first, the problem of the semantics and pragmatics of ought and might claims in philosophy of language; second, the debate on the perspectival nature of legal statements in legal philosophy; third, the debate on dispositional accounts of normative facts and values in metaphysics; and fourth the debate on collective intentionality in the philosophy of mind and action. Marques believes that there is a common set of issues underlying these seldom-connected debates. Her guiding research idea is that contextualist semantics is adequate for all normative statements, and difficult cases can be explained with a combination of (i) pragmatic accounts of the metalinguistic selection of appropriate standards, and (ii) proper accounts of collective intentionality. The project will pursue three objectives in particular: (O1) To develop the case for contextualism about deontic modals in the domain of normative legal statements and judgments. (O2) To investigate the role of joint commitments and collective intentionality in normative disputes, and the constitution of normative facts. (O3) To assess the relevance of the results achieved under O1 and O2 for the ongoing debate about legal positivism and the nature of law.";230036,6;230036,6;FP7-PEOPLE-2013-IEF;/MC-IEF;UNIVERSIDAD POMPEU FABRA;ES;;;;1;0;0;1;0;0 187664;622028;IITW;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IEF;FP7;Islands in the West;2014-10-01;2016-09-30;;"'The project 'Islands in the West' will present the first systematic study of the mythical islands of pre-Christian Europe: in a number of disciplines ranging from Scandinavian Studies to Classics, it has repeatedly been remarked that the mythological islands of Europe show striking similarities which might reflect far-reaching cultural contacts. Such remarks recur with great regularity, also in recent research contributions; this shows the widely interdisciplinary importance of the question. In spite of this, this topic has never been addressed by a dedicated study and the question is still not answered of whether these similarities in the mythical topography of Europe do indeed reflect processes of religious exchange. Nor has any attempt been made to determine what such processes could tell us about their social contexts and their importance in the life of people in early Europe. Recent methodological developments will now for the first time allow to address such questions on the basis of a methodology that is finding increasingly wide acceptance and which will make it possible to provide a methodologically well-founded and theoretically informed answer. The fellow is particularly suitable to tackle this task in the context of the IEF programme, as he has been a key contributor to the methodological developments which now permit to solve the question posed by the 'Islands in the West'. This topic has a particular importance for the ERA, as it addresses a prominent but so far neglected aspect of European cultural and religious history. It is of European-wide scale, reaching from Iceland to the Eastern Mediterranean, and should thus be addressed on a European level. It will have a scholarly impact both through its empirical results and through its methodological innovations. Beyond academia, the impact of its outreach activities will include the amendment of misconceptions about “Germanic” history created by the abuses of the term “Germanic” by NS-propaganda.'";161968,8;161968,8;FP7-PEOPLE-2013-IEF;/MC-IEF;LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN;DE;;;;1;0;0;1;0;0 187899;625032;DEMTUREUROPE;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IEF;FP7;Democratization and Transnational Human Rights Regimes: A Case Study of Turkey and the European Court of Human Rights;2014-10-06;2017-04-05;;"The proposed research project is concerned with the interaction between the European Court of Human Rights (ECtHR) and Turkey, and seeks to contribute to the understanding of the Turkish case by looking through the ECtHR lens and of the European human rights system through the Turkish lens. The project will be based on an empirical analysis of the impact of the ECtHR’s case law on democracy in Turkey based on the following typology of issues: 1) rights associated with ethno-linguistic group membership; and 2) rights associated with religious group membership. Each of these issues will be elaborated on the basis of: a) freedom of association and electoral rights (and freedoms of expression and assembly where relevant); and b) freedom of religion. The project will have a retrospective and a forward looking approach by examining the evolution of the case law over time, paying attention to critical junctures in: 1) the evolution of democracy in Turkey; and 2) the evolution of the European human rights regime. The methodology will be based on an examination of the case law (at the European and national level), interviews (in Turkey, Strasbourg and Brussels), secondary literature, review of official documents and media analysis. The project outputs will be: 1) a monograph published by an academic press, 2) peer-reviewed articles published in academic journals with open access, 3) a policy paper, and 4) an international conference in Turkey. Based on an interdisciplinary approach inspired from law, political science and sociology, the project aims to fill a gap in the literatures on Europeanization, transnational constitutional pluralism, legal mobilization and supranational human rights regimes, and to contribute to democracy and new governance studies.";223778,4;223778,4;FP7-PEOPLE-2013-IEF;/MC-IEF;HERTIE SCHOOL OF GOVERNANCE GGMBH;DE;;;;1;0;0;1;0;0 188029;626577;NARRATED INJUSTICE;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IEF;FP7;"Narrated Injustice Compensation Claims and Transgenerational Narratives of Injustice";2014-05-01;2016-04-30;;"Acknowledging historical injustice has become a major issue in a changing Europe since the End of the Cold War, but also worldwide, visible when the UN proclaimed 2009 the International Year of Reconciliation. Payments made by states to victims of historical injustice have become a common political practice, however, we still know little about how compensation desires are re-narrated across the generations, and how media and public debates shape those narratives of injustice. In the Netherlands one can study exemplarily how European post-war and post-colonial memories affected each other in the last decade and developed into a new form of claim culture. Therefore this project looks at two Dutch case studies, the payments made to Dutch Jewish victims since 2000 and how these payments became a reference-point for present (post-colonial) claims from descendants of former slaves, Surinamese and Dutch Antilleans. Analyzing both case studies in a comparative set-up will contribute to the understanding of the imaginations linked to such payments in the postmemory generation, to explore the multidirectionality of memory, and to specify the role of culture in such narratives of injustice. This project will be hosted in the research program on Understanding the Age of Transitional Justice: Narratives in a Historical Perspective at the NIOD, which will allow the Fellow to relate insights from Holocaust-research to present debates on post-colonial legacies, which will contribute to reflection upon Europe’s multiple identities. By getting involved in a vigorous network, discussing issues of transitional justice and memory from an interdisciplinary, transnational, and comparative approach, this fellowship will be of major importance for the Fellow’s development in terms of knowledge-transfer, creating new networks and leadership skills.";175974,6;175974,6;FP7-PEOPLE-2013-IEF;/MC-IEF;KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW;NL;;;;1;0;0;1;0;0 187888;624872;HEALTH ON THE MOVE;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IEF;FP7;Health on the move: Exploring the ethical, social, and political underpinnings of portable devices for healthcare and lifestyle;2014-09-08;2016-09-07;;"Portability of healthcare raises ethical issues that warrant attention: these include the relocation of health outside the clinic and attendant redistribution of roles and responsibilities; the blurring of established moral categories and distinctions; and value conflicts among stakeholders. While market and policy agendas invest in the vision of mobile technologies for healthcare, there is so far no systematic sociological and ethical analysis on this topic. This project aims to take the first steps to fill this gap in the literature through offering an assessment of how portable mobile health technologies (mHT) will shape and be shaped by the current system of values in healthcare. The project has the following objectives: 1) to map technologies, regulations and discourses around mHT; 2) to explore moral, social and political values in the practices of use and technology design of mHT; 3) to assess these values against the background of current normative and conceptual descriptions in regulations; and 4) to set an agenda for regulation at the policy, technology and user level. The approach relies on qualitative methods in order to explore the ethical and political dimensions of portability in healthcare and offer normative conclusions. This highly interdisciplinary project, conducted in a world-leading research institution in the areas of healthcare, policy, medicine and society, will enable me to reach three training and career objectives: 1) integrating my experience in ethics/philosophy of technology with a deeper understanding of sociology of medicine and health; 2) strengthening my skills in the analysis of healthcare policy documents and governance strategies; 3) complementing my philosophical training with robust qualitative methodological skills for research in the social science. The fulfilment of these objectives will furnish me with the competences required to conduct original academic research at the borders of philosophy and sociology of medicine.";221606,4;221606,4;FP7-PEOPLE-2013-IEF;/MC-IEF;KING'S COLLEGE LONDON;UK;;;;1;0;0;1;0;0 187771;623472;TEXTILESTUDIES;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IEF;FP7;Textile Studies: questions and issues between knowledge and knowhow;2014-08-01;2016-07-31;;'This research project explores the modern reconstruction processes of archaeological textiles and focuses on the intersection between Natural Sciences, Humanities, experimental methods and technical skilled practices. Taking an anthropological and an ethnographic approach, the project aims to highlight the topical concepts of “knowledge” and “know-how” as specific as well as complementary knowing processes and contributes to define the interdisciplinarity at work in the field of Textile Studies. The mobilization of several disciplines and methods leads to the establishment of a hybrid field of study that can be understood by taking into consideration the practices of knowledge, more than knowledge itself. How do the different methods at work, the specific research reference systems in the disciplines involved, and the knowing practices generated in the study of ancient archaeological textiles contribute to defining their objects and to creating a research field that is both unified and composite? How are the theoretical tools and technical skills available to the “experts” in all areas of Textile Studies coordinated and interconnected? Where and how is it possible to grasp their interaction, and ultimately to question it, first in its specificity and then within its broader epistemological implications? The ethnographic inquiry with the textile experts of the Danish National Research Foundation’s Center for Textile Research CTR (University of Copenhagen and National Museum of Denmark) and on their research programs will provide a description of Textile Studies 'in the making'. The objectives of this project are on four main axes: 1) Textile Studies, 2) Science and Technology Studies, 3) History and Anthropology of Knowledge, 4) Theoretical and Experimental Archaeology.';308587,8;308587,8;FP7-PEOPLE-2013-IEF;/MC-IEF;KOBENHAVNS UNIVERSITET;DK;;;;1;0;0;1;0;0 186125;624968;TPAB;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IOF;FP7;Toward a Phenomenology of the Anxious Body;2014-10-01;2017-09-30;;"The project, Toward a Phenomenology of the Anxious Body (TPAB), is a study of anxiety, which employs an interdisciplinary methodology involving philosophy, cognitive science, and psychoanalysis. Anxiety is the most common form of mental illness in the US and UK, affecting 18% of the population in the US and 13% in the UK. Despite this, a rigorous analysis of anxiety at both an experiential and conceptual level remains overlooked. The project attends to this oversight. To achieve this, the project uses an original and novel methodology that combines a first-person perspective with state-of-the-art research in cognitive science. The project involves spending two years during the outgoing phase at the University of Memphis, School of Philosophy where the applicant will gain technical and complementary skills by working with the leading figure in embodied cognition, Shaun Gallagher. Dr. Trigg will then return to University College Dublin, School of Philosophy for the final year, where he will transfer knowledge acquired in the outgoing phase under the mentorship of Dermot Moran, the leading specialist in phenomenology. The research findings are then implemented during the return phase at policy level through collaborative research with medical practitioners. The training objective for the project is to gain the necessary skills required to becoming an independent researcher at a leading research institution in the EU. This objective is possible thanks to several factors, such as the expertise of the host departments, the excellent infrastructure in place, and the existing synergy between the outgoing and return scientists-in-charge. The impact of the TPAB project on EU Excellence will be to position the issue of anxiety on the research horizon; to diversify the research horizon through the novel methodology; and to make an enduring contribution to the EU strategy for the future of mental health by tackling societal challenges such as stigma and exclusion.";263058,3;263058,3;FP7-PEOPLE-2013-IOF;/MC-IOF;UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN;IE;;;/LIF;1;0;0;1;0;0 186675;629341;SURROGARTS;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IOF;FP7;Assisted reproduction beyond the nation state and nuclear family? Transition to parenthood and negotiating relatedness in gay father families created through transnational surrogacy;2014-10-01;2017-03-31;;"The project aims to examine the experiences, meanings and practices of negotiating relatedness in European gay father families created through surrogacy and egg donation in the UK and, transnationally, in the US. The study of the under-researched and developing phenomenon of surrogacy seeks to identify how reproduction or subversion of mainstream family models by Assisted Reproduction Techniques (ARTs) is shaped by four factors: (a) genetic links between parents and children, (b) participation of more than two parents in the conception of the child, (c) intersected gender and sexuality of the parents, (d) social determinants such as class, race, nationality and bio-political institutions in the transnational context. The comparative framework of the US- and UK-based fieldwork enables comparison between the former free market of ARTs and the latter more regulated one. The theoretical relevance of the project lies in its objective to assess the implications of the current evolution of procreation and care relationships by evaluating the adequacy of the couple logic as opposed to networked-individual approaches. It thus responds, too, to the criticisms of closed adoption or donor anonymity within the framework of the debate on child commodification vs. the inclusion of minority families. The socially relevant and policy-related mobility problems of national register of children born through transnational and transcontinental reproductive tourism are tackled with a view to contributing to the debate on the possibility of a European framework for assisted reproduction. The candidate researcher’s training comprises the development of interdisciplinary methodology of sociological research that incorporates contemporary ethnographic approaches and thus better enables investigation into sensitive issues of intimate life. The skills transference envisages the candidate’s overall contribution into the development of the social study of reproduction at the return host centre.";239282,7;239282,7;FP7-PEOPLE-2013-IOF;/MC-IOF;THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;UK;;;/LIF;1;0;0;1;0;0 186748;630188;Wetland-EcoSysBiol;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-CIG;FP7;The hidden sulfur cycle in freshwater wetlands: an eco-systems biology approach to identify and characterize major microbial players;2014-03-01;2018-02-28;;Freshwater wetlands are a major source of the greenhouse gas methane but can also act as carbon sink, storing currently more than one third of the terrestrial organic carbon. Understanding their intertwined biogeochemistry and microbiology is therefore indispensable to foresee their influence to positive and negative climate feedback cycles. This proposal aims to elucidate the identity and ecophysiology of sulfate reducing microorganisms (SRM) driving a highly active but hidden sulfur cycle in wetlands, which is not apparent from the low standing pools of sulfate and thus has been severely understudied. Since sulfate reduction effectively competes with methanogenic degradation of organic matter, SRM have an important control function on methane production in wetlands. Little is known about wetland SRM. This stands in contrast to the high diversity of evolutionary deep-branching dsrAB genes, which are functional markers for SRM, indicating a large number of yet undiscovered SRM in wetlands. The expected scientific outcome of this proposal comprise: (i) identification of microorganisms involved in the hidden sulfur cycle with focus on SRM, (ii) elucidating their substrate preferences and preferred environmental conditions, (iii) identifying their interaction partners, and (iv) linking their function to their genome as well as their major transcripts and proteins. This will be achieved by an interdisciplinary approach, where (i) structure-function methods like stable isotope probing are linked to meta-genomics and -proteomics, (ii) high-throughput amplicon sequencing of phylogenetic markers and metatranscriptomics is combined with controlled experimental setups under monitored biogeochemical parameters, and (iii) by targeted cultivation of novel microorganisms. This proposal will be vital for me to build up an own research group, to strengthen my international collaborative network, and to maximize my integration in the European Research Area.;100000;100000;FP7-PEOPLE-2013-CIG;/MC-CIG;UNIVERSITAT KONSTANZ;DE;;;/LIF;1;0;0;1;0;0 185979;623876;HDIMSM;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IIF;FP7;Self-Assembled Virus-Like Particles from Polyferrocenylsilane-Based Polymers and Viral Capsid Proteins: Fabrication, Surface Engineering and Applications;2015-02-01;2017-01-31;;The capsid proteins of viruses have been shown to organize around a variety of non-biological polyanions, in a similar way that proteins assemble around RNA genomes, to form virus-like particles (VLPs). Metal-containing polymers such as polyferrocenylsilane possess additional interesting physical and chemical properties and may yield VLPs possessing very different morphologies and more diverse functionalities on co-assembly with capsid proteins. In a similar manner to almost all nanoscale objects, VLPs generally exist in the solid state but not in the liquid phase, because the scales of these systems are typically larger than the range of attractive interactions between such nanostructures. This situation comes with limitations regarding both storage and product formulation. Due to the recent development of liquid proteins via the surface engineering techniques, interest in the phase behavior of bionanomaterials has grown rapidly. The proposed research focuses on the fabrication and surface engineering of responsive VLPs through the self-assembly of polyferrocenylsilane-based copolymers and viral capsid proteins. This project is highly interdisciplinary and the project objectives will be accomplished by the proposed award of a Marie Curie Fellowship to a highly talented young scientist from China, Dr. Hongjing Dou. She has considerable expertise in the area of bionanomaterials and in biomedical science. The proposal involves her working at the School of Chemistry at the University of Bristol in the UK together with Prof. Ian Manners, who has expertise in the field of synthetic metallopolymers such as polyferrocenylsilanes and also self-assembly, and cosupervisor Prof. Stephen Mann, an expert in bio-inspired chemically-derived routes to complex materials and a pioneer of solvent-free liquid proteins and viruses, to achieve the ambitious project goals.;309235,2;309235,2;FP7-PEOPLE-2013-IIF;/MC-IIF;UNIVERSITY OF BRISTOL;UK;;;/LIF;1;0;0;1;0;0 186489;627740;MPPL;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IOF;FP7;Moral Progress and Political Limits. Liberal responsibilities in an age of shifting international power balances;2014-09-01;2016-08-31;;"The project will provide a better understanding of how the international responsibilities of the liberal state are constructed in an age of shifting power balances. It is an interdisciplinary study of the ethical reasoning of Australia, the UK and the US as it relates to R2P and the ICC. This is timely given speculation concerning the decline in the relative power of liberal states and the impact that may have on the ability and willingness of international society (including European states) to protect human rights, especially in the face of opposition from the emerging powers or “BRICS” (Brazil, Russia, India, China, and South Africa). This fault line widened during the 2011 Libya crisis and it is evident in the reaction to the ongoing crisis in Syria. It raises the question of whether and how this new context influences the pursuit of humanitarian ideals through the foreign policies of liberal states. The research questions to be answered are empirical and normative: do liberal states now conceive this diplomatic fault line as part of a ‘new reality’ that is forcing them to compromise on the moral ends / means of human protection?; is compromising on the ends / means of human protection an appropriate response? To answer these questions the project employs a ‘holistic’ approach to the study of ethical reasoning. This was set out by one of the project's supervisors, Christian Reus-Smit, with his collaborator Richard Price. It is at the cutting-edge of innovation in International Relations. Developing a competency in its application will elevate the fellow's career to a new level of maturity, enhance his international reputation and enable him to exercise leadership across the European Research Area. In addition he will receive complementary skills training from Tim Dunne and Edward Newman. This is to prepare the fellow for playing a leadership role in the creation of a European Centre on the Responsibility to Protect and Prosecute (EuroCoRPP).";280965,4;280965,4;FP7-PEOPLE-2013-IOF;/MC-IOF;UNIVERSITY OF LEEDS;UK;;;/LIF;1;0;0;1;0;0 186046;624433;EMIGRE;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IOF;FP7;European emigration governance - emigration and diaspora policies and discourses in the post-crisis era;2014-12-01;2017-10-10;;"The project breaks new ground in the study of migration governance by looking at the so-called immigration countries from the perspective of emigration governance. The main underlying theme of this research is that emigration and immigration are two sides of the same coin and thus European migration governance should be approached from two angles to understand its full dimension. European Union is in fact still a region of emigration, with majority of flows staying within its boundaries, but important numbers leaving EU every year. Following the current global trends emigrants should be perceived as a potential asset. ÉMIGRÉ analyses emigration and diaspora policies of four EU Member States (UK, France, Spain and Poland) as well as EU-level responses to emigration to understand what are the drivers of the emigration governance in Europe and how the policies actually work. Key objectives are: 1) To close the knowledge gap on migration from the EU. 2) To enrich international migration governance studies by providing comparative analysis of actions of EU States in regards to emigration management, over time. 3) To ask what is the relation between State identity formation/shifts and success of policy learning/policy transfer processes between levels of governance. 4) To contribute to evidence-based policy making at the EU level. The project focuses especially on EU emigration to other OECD countries and in particular Canada. It employs a wide range of interdisciplinary methods to collect and analyse data. It also offers an intensive training programme.";300754,25;300754,25;FP7-PEOPLE-2013-IOF;/MC-IOF;EUROPEAN UNIVERSITY INSTITUTE;IT;;;/LIF;1;0;0;1;0;0 185782;622358;HYBRIDSOLAR;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IIF;FP7;Morphology and Molecular Packing in Polymer-Nanocrystal Hybrid Solar Cells Revealed with Synchrotron X-ray Characterization and Other Techniques;2014-03-01;2016-02-29;;"Polymer-nanocrystal hybrid solar cells offer promise as a low-cost alternative to traditional solar cells due to their potential to combine the advantages of organic and inorganic materials to produce lightweight, flexible, and high-performance solar cells using low-cost solution processing. This project, which includes the first detailed synchrotron study of polymer-nanocrystal hybrid solar cells, will advance the understanding and performance of hybrid solar cells by demonstrating control of molecular packing and morphology in hybrid solar cells, correlating molecular packing and morphology with solar-cell properties and performance, and using the obtained knowledge to fabricate high-efficiency solar cells. The results will be of interest to researchers in a variety of fields and will be published in a series of high-impact journal articles and presented at materials science and chemistry conferences. The researcher will join the Solution-Processed Nanophotonic Devices (SPNP) group led by Professor Gerasimos Konstantatos at the Institute of Photonic Sciences (ICFO) in Castelldefels, Spain to complete this project. The SPNP group, an interdisciplinary team of physicists, chemists, and engineers, will share its knowledge of the design, synthesis, and modification of nanocrystals with the researcher. The researcher has extensive experience with organic solar cells and synchrotron characterization due to her research at the Stanford Synchrotron Radiation Lightsource (SSRL) as a PhD candidate at Stanford University and a postdoctoral researcher at Robert Bosch, LLC. The researcher will use her experience to perform the host group’s first synchrotron experiments and form lasting collaborations with SSRL and ALBA, a third generation synchrotron source less than 40 km from ICFO.";173370,6;173370,6;FP7-PEOPLE-2013-IIF;/MC-IIF;FUNDACIO INSTITUT DE CIENCIES FOTONIQUES;ES;;;/LIF;1;0;0;1;0;0 186082;624680;MANU;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IOF;FP7;Marine Aerosol NUcleations;2014-03-17;2017-03-01;;"The topic of this proposal is the natural marine aerosol, which is of paramount importance at the global scale and influences the Earth’s radiative budget and the biogeochemical cycles. New particle formation dominates the atmospheric aerosol number budgets and most of these particles are formed by nucleation of marine biogenic vapours. MANU (Marine Aerosol NUcleations) aims to directly identify the spontaneous creation of new nanometer-sized particles in the open ocean marine atmosphere and to understand the physical and chemical transformations occurring in them once formed. MANU will (1) obtain the spatial variability of new particle formation (NPF) events in different open ocean areas, (2) elucidate the chemical composition of NPF events, (3) associate NPF events with biological processes and (4) interpret how NPF events affect the existing aerosol and its overall Cloud Condensation Nuclei (CCN) population. The approach involves state-of-the-art mass spectrometry measurements including ATOFMS, HR-ToF-MS and Api-ToF/MS during a Southern Ocean research cruise (Hesperides, 2014) and at the Mace Head research station (Ireland, 2015). The expected outcome of this Marie Curie action is to contribute to a significant step in the career of the promising European researcher such as the candidate, specifically adding missing complementary research competencies at an advanced level of new particle formation events measurements. Additional benefits to the European knowledge-based economy and society will also come from the important return phase of the project, where the experience and the knowledge acquired as well as the contact-network built up outside Europe will be shared. This proposal is multidisciplinary because two institutions with different backgrounds (outgoing: atmospheric chemistry; return: marine biology) aims to tackle the interdisciplinary research topic of open ocean NPF events while transferring knowledge to the candidate and the public.";226444,1;226444,1;FP7-PEOPLE-2013-IOF;/MC-IOF;NATIONAL UNIVERSITY OF IRELAND GALWAY;IE;AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS;ES;/LIF;1;0;0;1;0;0 186849;631396;MEMOTUMCELLMACH;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-CIG;FP7;Metallodrugs to Modulate Tumour Cell Machinery;2015-01-01;2018-12-31;;"'The past decade has seen substantial advances in our understanding of cancer molecular biology and the technologies available to study it, emphasising the importance of the molecular mechanisms of carcinogenesis in cancer research. We now face having to therapeutically aim for many less common targets rather than a few all-cancer present targets. Effective single molecular targets therapies are generally not sufficient to elicit durable clinical responses and the development of drug resistance is an increasing problem. Consideration of only a single drug–target interaction in vivo has proven to be overly simplistic. The ultimate goal of this proposal is to generate metallodrugs whose mechanism of action is understood and whose targets are identified. These multitargeting drugs would be a more realistic option by leading rational co-extinction strategies for specific cancers. Current cross-discipline trainings make possible the alliance of inorganic chemistry with cell and molecular biology. The unprecedented potential for design of metallodrugs has not been overseen and medicinal bioinorganic chemistry is rapidly expanding. This interdisciplinary proposal involves chemistry, biology and physics, with potential not only for the discovery of novel medicines for cancer treatment, but also for the development of new methodologies to modulate and deconvolute the technology behind the tumour cell machinery. By uncovering the operating principles and mechanisms of action of our metallodrugs at the nanoscale (i.e. subcellular level) we aim to inform on what biological context its destruction would lead to cell death and also to tumour regression. These metallo-medicines will exploit the extraordinary features of transition metal complexes, in particular the capability for in tumour activation, and the possibility of being loaded into nanocarriers, conferring control on the drug reactivity, and thus minimising undesired side effects, often responsible for drug failure.'";100000;100000;FP7-PEOPLE-2013-CIG;/MC-CIG;FUNDACION IMDEA NANOCIENCIA;ES;;;/LIF;1;0;0;1;0;0 186786;630925;COHEAT;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-CIG;FP7;Coherent heat and energy transport in quantum systems;2014-03-01;2018-02-28;;"'We are nowadays capable of controlling and manipulating quantum systems as never before. Quantum technology is close to bringing IT devices to mass scale production. The improvement in the accuracy of fabrication and control of quantum systems starts to pay some results also in different fields of research and application, such as biology. Despite the successes already achieved, it is surprising that the problem of how quantum systems exchange energy is, from many points of view, still open. How to define work and heat at quantum level? Is it possible to design quantum devices that manage heat and energy transfer in an efficient way? Here we focus on a particularly promising way in which quantum systems can exchange energy and heat. Our experimental partners have shown that the heat transferred between two superconductors connected by a Josephson junction has a contribution that depends on the phase difference between the superconductors. As the phase difference can be controlled by a magnetic flux, this open a completely new way to manipulate and transfer heat at the quantum scale. We will study how to exploit this coherent heat transport. The objective of COHEAT is to develop techniques and design circuits aimed at controlling, measuring, distributing, storing and converting heat. COHEAT will lay the theoretical basis for what can be called “coherent caloritronics”. Similar analysis can be extended to other quantum systems as the Bose-Einstein condensates, which represent a test bench for more exotic cases, in which the systems are driven out of equilibrium. COHEAT will have a strong and interdisciplinary scientific and technological impact. The possibility to transfer heat at mesocopic scale, and to manipulate it fast, easily and locally, has countless applications: quantum computation, biology, nanoengineering to mention the most relevant ones.'";100000;100000;FP7-PEOPLE-2013-CIG;/MC-CIG;CONSIGLIO NAZIONALE DELLE RICERCHE;IT;;;/LIF;1;0;0;1;0;0 185733;621413;LEAPFROG M-ITI;ONG;FP7-REGPOT;ERACHAIRS-2013-1;FP7;Enhancing the Research and Innovation Potential of M-ITI through Human-Computer Interaction and Design Innovation;2014-05-01;2019-04-30;;"The goal of the project proposal is to seek funding in order to expand the research and innovation potential of the Madeira Interactive Technologies Institute (M-ITI) of the University of Madeira through the hiring of an ERA Chair in Human-Computer Interaction (HCI) and Design Innovation (DI). The LEAPFROG HCI-DI aims at unlocking the full potential of interdisciplinary research in interactive technologies, while strengthening innovation and knowledge transfer activities in close collaboration with local and global industrial partners and contributing to the smart specialization strategy of Madeira. To this end, funding this project proposal will support the following main activities: (i) Upgrade the RDT capacity and capability by expanding the human potential and fostering a critical mass of researchers with inter-disciplinary expertise in human-computer interaction (HCI); (ii) Improve M-ITI’s innovation potential and impact at the regional, national and European levels, through design-driven innovation. Such approach will unravel the impact of open innovation and crowdsourcing on education, training and knowledge transfer, and extend the creative research capabilities of individuals and organizations in the region and finallty (iii) Raise international awareness about the institute and connect M-ITI and its industry affiliates to the global knowledge networks. As a consequence of these activities we aim to better integrate M-ITI with the European Research Area (ERA) and, in particular, improve the participation of M-ITI and associated entities of the recently created regional system for R&D\I, thereby increasing the level of participation of the institute in the Horizon 2020 program.";2637190;2118781;FP7-ERAChairs-PilotCall-2013;/CSA-SA;MITI - MADEIRA INTERACTIVE TECHNOLOGIES INSTITUTE - ASSOCIACAO;PT;;;;1;0;0;1;0;0 185917;623436;GEOSINPO;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IOF;FP7;Geo-Spatial Modelling Informing Policy;2014-08-01;2017-07-31;http://shahumyan.org/project-geosinpo/;"The aim of this fellowship is for the applicant – Dr. Harutyun Shahumyan – to move from University College Dublin (UCD) in Ireland to University of Maryland (UMD) in US for two years and then return and build on his research at UCD for another year, for the purposes of enhancing his training in integrated modelling supporting smart and sustainable growth; and to provide complementary skills training that will assist the applicant in his career path in academia. The research training will be achieved through a project dedicated to emerging techniques centred on the development of Spatial Decision Support Systems (SDSS) and application of state of the art geospatial analytical tools, which are uniquely available within the scientific resource bases of the host institutions. This project will be delivered through practical application of different integrated modelling approaches in two study regions (1) Chesapeake Bay Watershed (CBW) in US during outgoing phase and (2) Greater Dublin Region (GDR) in Ireland during return phase. Strengths and weaknesses of each approach will be explored thoroughly; and the ways of complimenting each other will be suggested taking into consideration policy makers’ needs. The applicant has a remarkable academic track record with an Honour MS degree in Applied Mathematics, a PhD in Engineering followed by 8 years of Post-Doctoral research in statistical and spatial modelling. The applicant has co-authored 15 journal articles, 2 book chapters, 7 conference papers, 4 working papers and 5 research reports and has given poster and oral presentations at 17 international conferences. The outgoing host the National Center for Smart Growth Research and Education at UMD is one of the most prominent interdisciplinary centres of smart growth analysis and modelling with extensive practise in applications supporting policy makers. It has an excellent track record of training experienced researchers and engaging them with scientists & decision makers.";364476,9;364476,9;FP7-PEOPLE-2013-IOF;/MC-IOF;UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN;IE;;;/LIF;1;0;0;1;0;0 186010;624145;BUGS;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IOF;FP7;Biology of UnderGround Symbioses (BUGS): studies of a subterranean ant-aphid-microbe cooperative network;2015-01-01;2018-06-24;;"Mutualism, cooperative interaction between different species, is widespread in nature. Despite its ubiquity and recognised importance for ecological communities, how mutualism evolves and persists remain major unresolved questions in evolutionary biology. The reason for this is that mutualistic interactions can often be exploited by parasites, and high degrees of species interdependence can increase extinction risk. Applying established network theory to interpret biological details of mutualistic interaction networks has great potential to reveal crucial system properties such as enhanced network resilience through species interdependence. I propose an interdisciplinary study combining network theory with detailed empirical analyses of a so far uncharacterised mutualistic network of subterranean ants, aphids and microbes. The ants protect aphids from predators, and in turn harvest honeydew, processed plant sap excreted by the aphids. In addition, symbiotic gut bacteria in both ants and aphids synthesise essential amino acids and assimilate nitrogen. These bacteria are crucial for upgrading the sugar rich but otherwise nutritionally poor plant sap and honeydew. My project will improve our understanding of mutualisms by unravelling the metabolic and behavioural mechanisms underlying species interdependence in this specialised symbiotic network. To this end, I will (i) assess covariance between bacterial communities of associated ants and aphids, (ii) determine the functional roles of bacterial communities in honeydew composition, and (iii) assess ant behavioural specificity in choice of aphid partners. I will then (iv) further interpret my findings in a broader context by applying network theory to this focal network and other comparable mutualistic networks, thereby adding to our general understanding of the evolution and stability of mutualism.";270312,9;270312,9;FP7-PEOPLE-2013-IOF;/MC-IOF;STICHTING VU;NL;;;/LIF;1;0;0;1;0;0 185725;621321;BIO-TALENT;ONG;FP7-REGPOT;ERACHAIRS-2013-1;FP7;The creation of the Department of INTEGRATIVE PLANT BIOLOGY;2014-07-01;2019-06-30;;The superior idea of the BIO-TALENT project is to integrate staff members of the Institute of Plant Genetics, Polish Academy of Sciences with the European Research Area, enhance research competence and performance, generate an increase of knowledge, visibility and intensity of collaboration (existing and new) and establish long-lasting partnerships between academia and industry. High-quality research and industry will benefit from each other in two doctorates, with one being obligatory an industrial doctorate to our knowledge performed in Poland for the first time in plant genetics and related bio-sciences. Special attention will be paid to strengthening ties with high quality research institutions as well as with the end-users (farmers, agricultural advisers, industry and government). As primary business partners we forsee plant breeding stations as well as agrochemical companies. Funds allocated to this project will make possible to employ top-class experts with qualifications indispensable for the implementation of the long-term Institute's Development Strategy as well as to purchase the unique software and equipment contributing to better research performance. With the project accomplishment, the Institute will gain a competitive research potential to conduct interdisciplinary research on molecular genetics, genomics, resistance to stresses and bioinformatics at the Department of Integrative Plant Biology. The establishment of the BioTech unit will play a key role in this project coordinating cooperation with private sector and technology transfer. The project objectives will be achieved through a coherent set of the following actions: recruitment of the ERA Chair holder and the BIO TALENT team, collaboration, twinning and networking, knowledge transfer through workshops, seminars and lectures, industrial doctorates, participation in conferences, exchange of know-how and experience, study visits to transfer best practices, secondments to private sector as well as wide promotion of the project and various outreach activities.;2396248;1935839;FP7-ERAChairs-PilotCall-2013;/CSA-SA;INSTYTUT GENETYKI ROSLIN POLSKIEJ AKADEMI NAUK;PL;;;;1;0;0;1;0;0 185967;623783;STRATECHPOL;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IIF;FP7;Strategic Clean Technology Policies for Climate Change;2014-07-08;2016-12-07;;"Renewable energy targets and support programs form a major part of efforts to reduce greenhouse gas emissions in the E.U. and abroad—but not without controversy. Recent studies indicate that the implied abatement costs from European renewable energy policies are significantly higher than corresponding ETS allowance prices. Furthermore, the generators that benefit from these policies already operate in a market subject to the ETS cap, meaning that additional abatement via renewable energy can be offset by reduced effort among other covered units. Overlapping policy instruments can be justified by overlapping policy goals. In addition to domestic emissions abatement, stated rationales for renewable energy support include promoting technological innovation, exports, employment and energy security. One question is whether the extra cost of abatement from renewables over other alternatives is outweighed by these other benefits. Another is whether green industrial policy and trade promotion is consistent with WTO obligations. I propose to explore the value of clean technology programs above and beyond their emissions abatement potential, with a focus on innovation. The approach will blend economic theory, modeling, and empirical techniques and extend the literatures on environmental policy and induced innovation, directed technical change, and strategic trade policies. The methods will address key questions for interdisciplinary research in trade law and the environment. To what extent do clean energy technologies exhibit stronger external benefits than other innovating technologies, and to what extent do popular clean technology policies bring forth those benefits? Of particular interest is the potential role of international spillovers in clean energy technologies as a justification for aggressive renewable energy support, and whether the economics indicate that WTO law should make more room for green industrial policy.";241567,6;241567,6;FP7-PEOPLE-2013-IIF;/MC-IIF;FONDAZIONE ENI ENRICO MATTEI;IT;;;/LIF;1;0;0;1;0;0 186660;629202;ENERGIZING FUTURES;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IIF;FP7;Energizing Futures: Investigating the Infusion of IT and Design into Novel Foresight Practices;2014-05-19;2016-05-18;;"This project advances applied and theoretical research into novel foresight methods. Taking the governance of emerging energy technologies as a case, this research investigates scenarios mediated through cutting-edge gaming, visualization, simulation and design techniques. This project involves two phases of qualitative research to empirically investigate the make-up, impact and products of novel foresight methods employed in the energy sector. Drawing on perspectives of anticipation, materiality and governance in the field of Science, Technology and Society (STS), this project seeks to 1) create a taxonomy of mediated scenarios; 2) characterize the nature and workings of such innovative foresight practices; and 3) develop two in-depth case studies involving the use of such scenarios in the field of energy in order to reveal the varied configurations of agency, temporality and culture inscribed in the practice. Through these inquiries, this project builds up STS scholarship on anticipation and contributes to understanding best practices of foresight by elucidating the nature and workings of novel methods. Drawing on a strong existing research program and a well-developed international network of scenario practitioners and interdisciplinary scholars, this research is situated within the Technology and Innovation Management Division at the Danish Technological University’s Department for Management Engineering with Professor, Dr. Per Dannemand Anderson as the scientist in charge.";308587,8;308587,8;FP7-PEOPLE-2013-IIF;/MC-IIF;DANMARKS TEKNISKE UNIVERSITET;DK;;;/LIF;1;0;0;1;0;0 186716;629740;EHNS-RAP;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IIF;FP7;Energy Harvesting Networks - Resource Allocation and Performance Evaluation;2014-09-01;2017-01-30;;"The project will focus on the design and performance evaluation of algorithms for networks of energy harvesting wireless nodes. Recent advances in the areas of energy harvesting and ultra-low-power wireless communications will soon enable the realization of such networks. They will find applications in healthcare, manufacturing, public safety, and will serve as building blocks for the Internet of Things and Cyber Physical Systems. In a recent interdisciplinary project, the PI (with other co-PIs) developed prototypes of Energy Harvesting Active Networked Tags (EnHANTs – http://enhants.ee.columbia.edu ). Building on the success of EnHANTs, we will consider the theoretical design challenges related to wireless networking. We will focus on the design and performance evaluation of resource allocation and Medium Access Control (MAC) algorithms for wireless networks composed of energy harvesting nodes. The algorithms will take into account cross-layer considerations and will deal with various functionalities, including flow control, topology control, and routing and with various environment and technological constraints. The PI will visit Tel Aviv University (Israel), and hence, an important component of the project is transfer of knowledge to the European research community from Columbia University and the EnHANTs project. The project will expose European researchers and students to new problems, provide them access to the U.S. research infrastructure, and allow them to establish long-term collaborations with researchers in Columbia. We believe that the research and knowledge transfer activities will make an impact on the areas of Cyber-physical systems and Internet of Things, and will contribute to the European competitiveness in these emerging areas. Finally, an important component is outreach to school children and undergraduate students. We will expose them to science, engineering, and research concepts in order to motivate them to embrace research careers.";256148,4;256148,4;FP7-PEOPLE-2013-IIF;/MC-IIF;TEL AVIV UNIVERSITY;IL;;;/LIF;1;0;0;1;0;0 186237;625814;Risky Brains;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IOF;FP7;The Neurobiology of Aggression and Violent Behaviour and Its Social Implications;2015-02-01;2018-01-31;;"Since the 1990s, neuroscientists have made fundamental progress in the study of violence and aggression. Advances in the neurosciences and the development of new biotechnologies have helped to elucidate genetic variations and neural correlates of anti-social behaviour such as polymorphisms in the MAOA gene, alterations in serotonin activity, or dysfunctions in the neural circuitry of emotion regulation. This research may help to identify potentially risky individuals even before they show any anti-social behaviour and, therefore, promises to revolutionize prevention and intervention programmes. Despite the undeniable relevance and importance of this topic, there are only very few social science studies that investigate the neurobiology of aggression and violence. To date, no systematic, sociological analysis of neurobiological research on anti-social behaviour, its social framing, or its manifold social and political implications exists. This project will provide the first comprehensive overview and critical analysis of the neurobiology of violence and aggressive behaviour from a social science perspective. The general objective is to analyse how violence and aggression are studied in the neurosciences and to outline the social and political implications associated with this research. With its interdisciplinary focus at the intersection of the neurosciences and the social sciences, the project will open up new perspectives in the study of violent and aggressive behaviour that transgress traditional disciplinary boundaries. It will, thus, make an important contribution to the theoretical reflection of science and technology in society and also inform future neurobiological research.";262975,2;262975,2;FP7-PEOPLE-2013-IOF;/MC-IOF;UNIVERSITAET HAMBURG;DE;JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN;DE;/LIF;1;0;0;1;0;0 186413;627162;INTERSEXIONS;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IOF;FP7;The Sociological Aspects of the Management of Intersexuality;2014-09-01;2017-11-30;;"In June 2013, the Foreign Affairs Council of the European Union adopted guidelines to promote and protect the enjoyment of all human rights by sexual minorities, including, for the first time, intersex persons, those who are born with chromosomal, hormonal, and/or anatomic variations, that do not fit the typical definitions of female and male. In March, again for the first time, the United Nations Special Report on Torture recommended the member States to avoid unnecessary surgical and pharmacological interventions often used to “normalize” primary and secondary sexual characteristics in intersex children. The present project aims to investigate, in a comparative and diachronic way with an interdisciplinary approach, the medical, juridical, and social practices adopted in the management of intersexuality in Europe (focusing on the Italian case, where a conspicuous intersex movement does not exist yet) and in the U.S. (the cradle of the intersex movement). The goals of the research are: to investigate the socio-cultural changes in commonly adopted intersex protocols over time and their significance for the social actors involved; to analyze the intersex people’s (those medicalized and not) points of view; to inquire into how feminist movements and GLBTQ (Gay, Lesbian, Bisexual, Transgender, Queer) organizations, which focus on self-determination rights, deal with (or not) the intersex issue, and the links among them; to analyze the different strategies adopted by intersex associations, depending on their viewpoint (pathologizing or not); to identify the best practices vis-?-vis intersex issues in the U.S.,, Europe, and the rest of the world; to contribute to the debate on the power dynamics found within the gender binary structure, heteronormativity, and bioethics. The methodology is a combination of quantitative (using the few collective data available) and qualitative (in-depth interviews, autobiographical narratives, digital ethnography) sociological research.";350669,8;350669,8;FP7-PEOPLE-2013-IOF;/MC-IOF;UNIVERSITA DEGLI STUDI DI VERONA;IT;;;/LIF;1;0;0;1;0;0 186655;629114;STRUCTURED LIGHT;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IIF;FP7;Structured Light in Photonics Media;2014-03-01;2016-02-29;;"Over the last decade structured light in free space — light with a special shaped that endow it with unique propagation characteristics — has led to many exciting new applications, from microscopy and micromanipulation to micromachining. Also, these concepts have gone beyond optics and penetrated other fields, like electron beams. At the same time, researchers have demonstrated new kinds of “photonic media”, among them, photonic crystals, metamaterial, plasmonic materials and photonic lattices. In order to unfold the possible applications of these new photonic media it is essential to have control over the electromagnetic fields propagating within them. The objective of this proposal is to discover new structured electromagnetic waves and beams with unique propagation characteristics in photonic media. By finding how to control the light by just shaping its initial structure, this work will not only make fundamental theoretical contributions to optics and photonics, but will pave the way for new applications. Also, because some wave phenomena are universal, we anticipate that some of our result will contribute to control wave fields of different nature and therefore, it will have an interdisciplinary impact beyond optics. To achieve this, I will study of the Maxwell equations in order to find new solutions, new approximations and, new and better description of the electromagnetic waves and its propagation in photonic media. Also, I will implement simulation of the proposed electromagnetic beams and waves in order to verify, to characterize and to visualize the new physical phenomena. This project will take place at the Technion, under the supervision of Prof. Mordechai Segev. My research experience in structured light and my advanced mathematical knowledge and skills combined with the experience and physical intuition of Prof. Segev, are an ideal combination to trigger many new ideas and discoveries, at the forefront of current research.";256148,4;256148,4;FP7-PEOPLE-2013-IIF;/MC-IIF;TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY;IL;;;/LIF;1;0;0;1;0;0 186096;624803;COSMICMAG;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IOF;FP7;Evaluation of the Uncertainties of the Galactic Magnetic Field to Elucidate the Origin of Ultra-High Energy Cosmic Rays;2014-09-01;2017-08-31;;"'We propose to develop a new analysis approach for charged particle astronomy to find the astrophysical sources of cosmic particles with extreme energies. During the recent years, there has been a rapid progress in our understanding of Galactic magnetic field (GMF) and the collected statistics of ultra-high energy cosmic ray events. It should therefore be possible to correct the measured arrival directions of cosmic rays on Earth for deflections in the GMF and to significantly improve the search for their astrophysical sources in this way. The research objectives of this proposal are therefore: 1) A thorough evaluation of the uncertainties of the GMF with the aim of producing sky maps of the deflection uncertainty of cosmic rays given their arrival direction and rigidity (= energy divided by charge). 2) Development of an optimal analysis method for correlation studies that takes into account the deflection uncertainties originating from the uncertainties in both, GMF and the estimated rigidities. 3) Application of the optimal data analysis method to data of the Pierre Auger Observatory. During the outgoing phase, the fellow will join the astrophysics group of the New York University to acquire state-of-the art knowledge on the interpretation of astrophysical data relevant for the GMF. At the return host, the Karlsruher Institute of Technology, he will apply the obtained knowledge to data of the Pierre Auger Observatory. This project will allow the fellow to be trained in the theoretical foundations and computational tools needed to study the GMF. It will broaden his knowledge in astrophysics and therefore complement his current expertise of the particle physics of air showers. The interdisciplinary training and the possibility to gain teaching experience at both hosts, will contribute to the long-term development of the fellow’s career and make him eligible for a leading academic position in Europe.'";338362,4;338362,4;FP7-PEOPLE-2013-IOF;/MC-IOF;KARLSRUHER INSTITUT FUER TECHNOLOGIE;DE;;;/LIF;1;0;0;1;0;0 186234;625795;Smart-FiWi-HetNets;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IIF;FP7;Advanced Coordination Paradigms for FiWi Enhanced HetNets and Smart Grid Applications;2014-03-01;2015-02-28;;Converged fiber-wireless (FiWi) access networks may be viewed as the endgame of broadband access. Most of the past layer-2 and layer-3 FiWi research activities have been focusing on cascaded Ethernet passive optical network (EPON) and WLAN-mesh networks, or to a lesser extent also WiMAX. In this proposed research project, we explore new interdisciplinary possibilities and investigate novel ways of exploiting low-cost Ethernet based FiWi access networks to address key open research challenges of emerging 3GPP LTE-Advanced heterogeneous networks (HetNets). The objectives of the research project are threefold. First, we design and investigate high-capacity low-latency next-generation PON based mobile backhaul infrastructures with direct communications between collocated optical network units and base stations or WiFi access points as well as multi-failure recovery capabilities. Second, we develop and evaluate the performance of advanced traffic steering techniques based on cell association, biasing, re-selection, and dual-mode user equipment assisted base station/access point switching and combine them with real-time self-healing techniques to develop self-healing solutions for FiWi enhanced HetNets with multipath WiFi offloading capability of mobile data traffic. Third, we study the potential and involved technical challenges of enhancing FiWi access networks with wireless and passive fiber optic sensors to enable machine-to-machine (M2M) communications. We investigate the coexistence performance of event-driven M2M traffic and conventional human-to-human (H2H) traffic taking emerging low-power WiFi and Sub 1 GHz WLAN technologies into account and develop energy- and traffic-aware contention resolution and coordination techniques for event-driven M2M communications in FiWi-HetNet based smart grid communications infrastructures with reduced signaling overhead, decreased M2M access delay, and wide area situational awareness (WASA) for fast fault recovery in smart grids.;115018,3;115018,3;FP7-PEOPLE-2013-IIF;/MC-IIF;CENTRE TECNOLOGIC DE TELECOMUNICACIONS DE CATALUNYA;ES;;;/LIF;1;0;0;1;0;0 185861;622976;NETWORKEU8000;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IIF;FP7;Network of the first farmers - anticipation of European Union 8000 years ago;2014-05-01;2016-04-30;;"'The project is a migration study of a compact population group into a new natural-climatic zone and its existence in new cultural surroundings. As example will be given the Linear Pottery (LBK) and Starèevo Cultures. They were the first farmers in Central and South-East Europe, existed in neighbouring territories and were synchronous during 250 years from 5650 to 5400 BC. This research includes several aspects: • Economic/social reasons for migrations; • Adaptation of newcomers to the new environments; • Changes in the culture of the newcomers; • Formation of the new culture with syncretic traditions as a result of the coexistence of two cultural groups. This research is interdisciplinary: • Typology is applied for the analysis of archaeological materials. • Radiocarbon dates define a sequence of cultural changes and a scheme of cultural interactions. • The detailed scheme of climatic changes will be used to give an explanation of this Starèevo migration, the origins of the LBK and forms of adaptation of the first farmers. • The comparative-historical method with the use of ethnographical data will allow reconstructing the forms of human adaptation to climatic changes and different types of cultural contacts. Contacts between these cultures belonged to the non-directed type, when the innovations were integrated into another culture according to cultural interests. However the formation of LBK was associated with another type of contact, when during distribution of the new cultural group in local surroundings a merging of both cultures with a predominance of the intrusive culture took place. Our model of 'cultural transfer' will include an adaptation of new elements by separate individuals with their distribution among members of the society due to factors of prestige/practical significance, the modification of their shape and/or semantic content in the final integration into the cultural matrix.'";248379,6;248379,6;FP7-PEOPLE-2013-IIF;/MC-IIF;NATURHISTORISCHES MUSEUM;AT;;;/LIF;1;0;0;1;0;0 186298;626373;TCSTURKEY;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IIF;FP7;Analysis of Boolean Functions for Algorithms and Complexity;2014-03-31;2015-03-30;;"'The researcher, Dr. Ryan O'Donnell, received his Ph.D. from the Mathematics Department of the Massachusetts Institute of Technology (MIT) and is now an Associate Professor in the Computer Science Department of Carnegie Mellon University (CMU). Both departments are ranked #1 by the U.S. News & World Report. The host institution will be Bo?aziçi University in Istanbul, Turkey. Broadly speaking, Dr. O'Donnell's area of research expertise is Theoretical Computer Science ('TCS'), in the sense of Algorithms and Computational Complexity Theory. More precisely, Dr. O'Donnell's work takes an interdisciplinary approach, developing new tools and ideas in mathematics in order to understand the design, analysis, and limitations of basic computational algorithms. Dr. O'Donnell's mathematical research is primarily in the newly emerging area of Analysis of Boolean Functions (also known as Discrete Fourier Analysis), a subfield of of probability theory and real analysis. The overarching goal of the research proposed herein is to innovate new discrete-analytic tools for application in Theoretical Computer Science. Key research objectives: AAC: Prove the Aaronson-Ambainis Conjecture regarding influences of low-degree bounded polynomials. This conjecture has important consequences for Quantum Computation. FEI: Prove the Fourier Entropy-Influence Conjecture of Friedgut and Kalai. This conjecture has important consequences for Computational Learning Theory. SOS: Investigate the power and limitations of the Sum-of-Squares Method in combinatorial optimization. This is a very recently developed, extremely powerful optimization technique. NPH: Prove new NP-hardness-of-approximation results for the most basic CSPs like Max-Cut and 2Sat. This is plausible in light of recently developed Boolean analysis techniques due to Dr. O'Donnell and S.O. Chan. SSE: Explore the Small-Set Expansion Conjecture. The goal is to find new families of hard instances or to show that the SOS method succeeds.'";115773,6;115773,6;FP7-PEOPLE-2013-IIF;/MC-IIF;BOGAZICI UNIVERSITESI;TR;;;/LIF;1;0;0;1;0;0 185848;622890;MOLEGRO;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IOF;FP7;A stochastic model of eye lens growth with implications for cortical cataract formation;2014-09-01;2017-08-31;;"Humans have lenses in their eyes; to focus light on the retina. The lens must be precisely built, flexible, and remain transparent throughout life. If anything fails, our ability to see is seriously affected. Lack of flexibility affects practically everyone over the age of 50. Cataract affects transparency and is the most common cause of blindness in the world. The biological lens grows throughout life, via a complex, but still regular process. Starts with some 350 mitotically-active cells and reaches some 7 million cells in a 60 year old human. How to describe and understand such a remarkable process? What is its effect on pathological developments? Even data collection looks extremely difficult, while the sheer complexity of the problem requires truly interdisciplinary approach, including the help of advanced mathematics. Thanks to the unprecedented technological development, it is now possible to label single cells within the eye lens, and to follow the path of its daughter cells. The Bassnett lab at Washington Univ School of Medicine is the leader in this labelling technique and has a very ambitious program to answer questions above. Two years ago we joined Prof. Steven Bassnett in this fascinating endeavor. We bring more than 20 years of research experience in probability theory and mathematical analysis, leadership on several NSF grants, as well as more than 10 years of leading the Division of Prob. & Stats, Dept of Mathematics, Univ of Zagreb. We propose to develop mathematical models of various stages in the growth of the lens. Initial period of our collaboration is completed and we are now at the level where daily contact is needed. Our model is Markov in nature, and would involve branching processes with immigration and emigration. At the ultimate level we need to consider also measure-valued processes, technically a highly demanding topic. We plan to return to Zagreb and fully develop student program and research group in biomedical mathematics.";336315;336315;FP7-PEOPLE-2013-IOF;/MC-IOF;FACULTY OF SCIENCE UNIVERSITY OF ZAGREB;HR;;;/LIF;1;0;0;1;0;0 186427;627270;OHMWIT;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IOF;FP7;Online Health Monitoring of Wind Turbine Generators and Power Converters;2015-01-01;2016-12-31;;"This proposal is a 24-month Marie Curie IOF scheme which involves a British experienced researcher to undertake a training-through-research project on the development of cutting-edge wind turbine health monitoring technologies in liaison with Massachusetts Institute of Technology (MIT), USA. Dr Wenping Cao has been conducting original research into electrical machines and power electronics at QUB, and has established an excellent track record. MIT is a world-leading research institution in the field with an international reputation of technological innovation, enterprise participation, and knowledge transfer. This project will integrate a novel online condition monitoring system into the wind turbine drive train to detect incipient electrical winding and bearing faults in the generators (e.g. doubly-fed induction generators and permanent magnet synchronous generators), and to estimate failure/ageing conditions of power electronic devices (e.g. insulated-gate bipolar transistors, silicon carbide metal-oxide-semiconductor field-effect transistors and DC-link capacitors). It will help the EU to tackle climate change and contribute to the EU’s economy by developing next-generation resilient wind turbine systems and significantly widening the competences of the fellow to reach his professional maturity with interdisciplinary expertise and complementary skills unique to the ERA. It is timely because: (i) there is a pressing need for reliable and cost-effective condition monitoring technologies for wind turbines, especially for those large ones installed in offshore environments; (ii) the applicant is leading the development of QUB’s teaching and research activities in wind energy and the highest quality training under supervision of internationally leading scientists is indispensable for his career development which will in turn benefit the UK and the EU.";273196,6;273196,6;FP7-PEOPLE-2013-IOF;/MC-IOF;ASTON UNIVERSITY;UK;THE QUEEN'S UNIVERSITY OF BELFAST;UK;/LIF;1;0;0;1;0;0 186519;628012;EMOWELF;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IOF;FP7;Emotional Welfare: From Brotherly Love to Fraternity;2015-02-01;2017-01-31;;"The experienced researcher, Dr. David Lederer, seeks secondment to the Australian Research Council Centre of Excellence for the History of the Emotions (outgoing host) for one year. There he will join the Centre at the University of Adelaide, collaborating with the other four hubs in Brisbane, Melbourne, Sydney and Perth. His research on emotional welfare examines sixteenth-century utopian social reform based on brotherly love; its practical implementation by humane/lifesaving societies according to the enlightened doctrine of sympathy; institutionalization by modern nation states as the principle of fraternité (French Revolution); and effects of global transmission by missionaries (case study Australia). Emphasis is on historical development of public health and safety policies and mental health care. He then returns to Queen Mary's University, London (return host) for one year to affect knowledge transfer at the Wellcome Trust Centre of Excellence for the History of the Emotions under Prof. Colin Jones (scientist in charge), with collaborations in Germany and Holland. This transfer includes the experienced researcher’s knowledge of the Australian model for large-scale interdisciplinary project funding in the humanities with multifaceted attention to public impact (public history, museum exhibition and the performing arts). Upon completion, the experienced researcher will have organized one international conference, presenting at others, prepared two articles and co-edited a special issue for publication in peer-reviewed journals, drafted one synthetic monograph, designed a new undergraduate syllabus and a master class, and organized a touring public exhibition. Thereafter, the experienced research will organize an Irish research cluster as PI and prepare a major funding proposal for international collaboration. As career progression, these achievements represent significant milestones toward a posting as full professor at a European research institution.";280965,4;280965,4;FP7-PEOPLE-2013-IOF;/MC-IOF;QUEEN MARY UNIVERSITY OF LONDON;UK;;;/LIF;1;0;0;1;0;0 186318;626470;MPFP;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IIF;FP7;Membrane protein dynamics and interactions;2014-06-01;2016-05-31;;Many important protein families such as signaling receptors, ion channels, structural proteins and enzymes are embedded in the membrane of cells. Despite their importance, understanding of their structure, dynamics and interactions lacks behind that of soluble proteins due to their hydrophobic nature which makes them difficult to study experimentally. We propose to recruit and retain in the Division of Metabolic and Vascular Health at the University of Warwick, Judith Klein-Seetharaman, membrane protein expert from the University of Pittsburgh, USA. In an interdisciplinary approach combining computational and experimental studies, she looks at these proteins from both, structural and systems biology point of views. She proposes to study membrane protein folding by characterizing denatured states of the model system and G protein coupled receptor mammalian rhodopsin in molecular detail by predicting these states and experimentally validating them with biophysical approaches such as 19F NMR spectroscopy. She will extend these studies to mutant rhodopsins that cause the retinal degeneration disease Retinitis pigmentosa and that are known to misfold and to other membrane proteins, in particular carnitine palmitoyltransferase 1A, of particular interest to our division. She will also investigate interactions of proteins with lipids using coarse grained simulations and in a systems biology approach interactions with other proteins to define the human membrane receptor interactome by establishing new collaborations within the division and with the Chemistry department. In this approach, computational machine learning methods are used to integrate large –omics databases to predict what interactions are likely for any given membrane receptor and then test the predictions using surface plasmon resonance and the TOXCAT assay. She proposes to disseminate her results in lecture series, conferences, a website, journal publications and through implementation of a graduate course.;309235,2;309235,2;FP7-PEOPLE-2013-IIF;/MC-IIF;THE UNIVERSITY OF WARWICK;UK;;;/LIF;1;0;0;1;0;0 186852;631427;TECHDEM;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-CIG;FP7;Technocracy and Democracy: convergence, conflicts and negotiations. A comparative and global analysis of expert knowledge and political power (18th to 21th century);2014-06-15;2016-11-07;;The relationship between knowledge and power represents a widely discussed issue in several social sciences and humanities. The TECHDEM research project at the CSIC (Consejo Superior de Investigaciones Científicas, Madrid, Spain) explores the origins of technocracy, examining the ways in which special or expert knowledge has become a source of legitimacy in public debate and in political decision-making. It is an interdisciplinary research that combines approaches stemming from history, history of science and technology, philosophy and sociology of professions. Using the case of experts (mainly engineers and physicians) who have carried out their activity in the northern Mediterranean in the period from the eighteenth century until nowadays, the project pays attention to issues such as the emergence and transformations of the definition of expert knowledge and the ways in which expertise has been acquired and certified. The project also explores how expert arguments and controversies have been inscribed in public debate as well as the ways in which the notion of objective and useful knowledge interacts with key notions of a given period such as “common good”, “public will” or “legitimate search for private interest”. The project does not remain at the level of a discourse analysis, as it also focuses on institutionalisation of expert practices within the government, in the private sector and in the so-called civil society, including the study of the experts’ capacity to mobilise financial resources. In general, the aim is to trace the roots of the raison technique and explore its different forms and transformations in order to set a basis for a well-informed public debate about the relationship between technocracy and democracy, between expert and public opinion, in the society today.;50000;50000;FP7-PEOPLE-2013-CIG;/MC-CIG;UNIVERSIDAD AUTONOMA DE MADRID;ES;AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS;ES;/LIF;1;0;0;1;0;0 185790;622439;SICOMIN;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IOF;FP7;Silicon carbon oxide minerals at extreme pressure and temperature conditions;2015-02-23;2018-02-22;;"The objective of this research project is to synthesize Si-C-O-based minerals under extreme pressures and temperatures (several tens of GPa and thousands of degrees) and study in situ their structure stability and physical properties at Earth’s mantle conditions. Experiments will be performed using cutting-edge techniques such as diamond-anvil cells and high-power heating lasers together with concurrent complementary characterization techniques, such as Raman spectroscopy or x-ray diffraction in synchrotron radiation facilities. Recent results suggest that these two compounds, CO2 and SiO2, could react at high pressure-temperature. The model system SiO2-CO2 is, however, compositionally not representative of the Earth’s mantle. Thus, in a second stage we will undertake experiments in the more complex Mg-Si-C-O system. The resulting framework Si-C-O-based minerals could be potential candidates of major host of oxidized carbon in the Earth. The discovery of these compounds would give rise to a completely new class of oxides of great interest for Earth and materials sciences. The results will be compared with ab initio simulations, giving a detailed and consistent experimental and theoretical picture of HP-HT Si-C-O mineral physics. Our group has already performed a theoretical search finding two possible HP-HT thermodynamic stable polymorphs. The expected results will allow accurately determining the thermodynamic parameters at the carbonate-silicate stability boundaries which are crucial for understanding the nature of the carbonate-silicate geophysical cycle. In addition, the project seeks to setup a table-top mineral laser-heating facility in Valencia. Developments made could be later transferred to the high-pressure MSPD beamline at ALBA synchrotron. In summary, this Marie Curie IOF Fellowship will fund a high-risk/high benefit interdisciplinary project and will facilitate the definitive candidate’s transition to the high-quality European scientific workforce.";352176,3;352176,3;FP7-PEOPLE-2013-IOF;/MC-IOF;UNIVERSITAT DE VALENCIA;ES;;;/LIF;1;0;0;1;0;0 185496;607737;VASCO;ONG;FP7-SECURITY;SEC-2013.2.1-1;FP7;a Virtual Studio for Security Concepts and Operations;2014-03-01;2017-02-28;;"The concentration of government buildings within urban environments has become a source of serious security vulnerability. Administrators and security experts face a variety of evolving threats that are hard to anticipate. To secure a government building against multiple threats while maintaining a minimal level of transparency and accessibility requires an integral security approach. It demands interdisciplinary collaboration between different experts from different domains. Currently, there is no efficient method or tool that allows the experts of different stripes to efficiently design, evaluate and implement appropriate security concepts. Existing ones do not allow for the effective creation, analysis, assessment, and sharing of security concepts that will help government administrators provide a secure environment for personnel and citizens. The VASCO project addresses two important objectives. First, it will design, implement and evaluate an innovative IT tool that will enable security professionals and administrators to jointly formulate, test, and adjust security concepts and measures in a virtual environment. This provides a cost-effective and risk-free environment in which to devise an evidence-based, all-risk approach for the protection of government buildings. Second, it will produce a knowledge and best practice database, which captures dynamic and visual reference scenarios created with the VASCO system. To accomplish these aims, the project will adopt an iterative methodology that enables the constant involvement of its world-class security and crisis management experts, assisted by a solid and open user group, during the whole project. It makes use of the latest advances in interactive visualisation, simulation, crisis management, and artificial intelligence to provide end-users with a new tool that significantly improves the way in which they collaborate to secure critical government assets both at home and abroad.";4151940;3037341;FP7-SEC-2013-1;/CP-FP;DIGINEXT;FR;"CENTRO DI RICERCA SVILUPPO E STUDI SUPERIORI IN SARDEGNA SOCIETA' A RESPONSABILITA' LIMITATA;IMMERSION SAS;Crisisplan B.V.;Försvarshögskolan, Swedish National Defence College;CONSIGLIO NAZIONALE DELLE RICERCHE;KENTRO MELETON ASFALEIAS";"IT;FR;NL;SE;EL";/SAF;1;0;0;1;0;0 185536;612782;POWER2YOUTH;ONG;FP7-SSH;SSH.2013.4.1-2;FP7;‘Freedom, dignity and justice’: A comprehensive approach to the understanding of youth exclusion and the prospects for youth inclusion and overall change in the South and East Mediterranean;2014-03-01;2017-05-31;;"The 2010-2011 youth-led wave of protests in the South and East Mediterranean, could be described as the coming on the scene of a new generation united by a shared experience of marginalisation and by new ways to protest and act. Important as this phenomenon could be for the future of the SEM, it still escapes the main frames of analysis utilised by academic research. Youth studies in the SEM, while producing important findings and insights, have failed so far to give a multi-dimensional and comprehensive understanding of the economic, political and social disadvantages faced by youth in the region and of the possible evolution of young people’s role in national or regional developments. This project aims at filling this important gap in our knowledge of the SEM by offering a comprehensive multi-level, interdisciplinary and gender-sensitive approach to the understanding of youth in the region. By combining the economic, political and socio-cultural spheres and a macro (policy/institutional), meso (organisational) and micro (individual) level analysis, POWER2YOUTH will explore the root causes and complex dynamics of youth exclusion, while investigating the factors fostering youth inclusion. Building on a conceptualisation of youth that gives prominence to youth as potential agents of change, the project starts out from the assumption that youth exclusion is the result of unequal power relations in society, in as much as effective youth inclusion can only be fostered by a bottom-up process of transformation of the systemic inequalities that lead to exclusion in the first place. From this premise comes the project’s emphasis on the study of the potentially transformative impact of individual and collective youth agency searching for instances of empowerment leading to active youth participation in society and overall change. POWER2YOUTH will finally produce innovative and concrete policy recommendations.";3426112,61;2499975;FP7-SSH-2013-2;/CP-FP-SICA;ISTITUTO AFFARI INTERNAZIONALI;IT;"THE BOARD OF TRUSTEES OF THE BIR ZEIT UNIVERSITY;ISTANBUL BILGI UNIVERSITESI;UNIVERSITE DE GENEVE;UNIVERSITE MOHAMMED V DE RABAT;SCHOOL OF ORIENTAL AND AFRICAN STUDIES, UNIVERSITY OF LONDON;American University of Beirut;FORSKNINGSSTIFTELSEN FAFO;UNIVERSITY OF DURHAM;UNIVERSITY OF LEICESTER;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;OBSERVATOIRE NATIONAL DE LA JEUNESSE;THE AMERICAN UNIVERSITY IN CAIRO;UNIVERSITE MOHAMMED V-SOUISSI";"PS;TR;CH;MA;UK;LB;NO;FR;TN;EG";"/SOC;/POL";1;0;0;1;0;0 185601;615613;EXQUISITE;ONG;FP7-IDEAS-ERC;ERC-CG-2013-PE3;FP7;External Quantum Control of Photonic Semiconductor Nanostructures;2014-04-01;2019-03-31;;In this project, we will control photonic nanostructures by external feedback, optical injection and synchronization. This will allow us to study nonlinear dynamics in quantum systems and to externally manipulate and stabilize light-matter interaction in the regime of quantum electrodynamics (cQED). We will experimentally and theoretically address a) optical injection and feedback control of quantum dot (QD)–microlasers, b) quantum control cQED systems via delayed single photon feedback, and c) mutually coupled and synchronized chaotic microcavity systems. In a) we will advance the concepts of time-delayed coupling in standard semiconductor laser diodes to few photon states, where quantum fluctuations contribute to or even dominate over the usual classical dynamics. Feedback-coupling in microlasers will allow us to explore the limits of a classical description of chaotic laser dynamics via the Lang-Kobayashi rate equations and to develop an advanced model taking cQED- and QD-specific effects into account. This subject will be complemented by the study of optical injection of coherent light and non-classical light into microlasers to influence and study mode-locking, chaos and stimulated emission down to the quantum level. Single photon feedback in b) will be applied to stabilize coherent coupling of light and matter and to act against decoherence which constitutes a major bottleneck for application of semiconductor nanostructures in quantum information technology. In c) the mutual coupling of microlasers will be used to study synchronization of chaotic quantum devices at the single photon limit and to explore the underlying physics of isochronal synchronization. Our work will have important impact at an interdisciplinary level on the development of nonlinear dynamical systems towards the quantum limit and the understanding of fundamental light-matter interaction in the presence of time delayed single photon feedback.;1999800;1999800;ERC-2013-CoG;/ERC-CG;TECHNISCHE UNIVERSITAET BERLIN;DE;;;"/PSE;/SCI";1;0;0;1;0;0 185544;614278;SESyP;ONG;FP7-IDEAS-ERC;ERC-CG-2013-SH3;FP7;Identifying Social-Ecological System Properties Benefiting Biodiversity and Food Security;2014-06-01;2019-05-31;;Ensuring food security and halting biodiversity decline are urgent, interconnected challenges. Drawing on the natural and social sciences, I propose an interdisciplinary research agenda to address these challenges. My goal is to develop a global theory that explains which properties of social-ecological systems benefit both biodiversity conservation and food security (and which benefit one but not the other). This holistic, systems-oriented approach radically differs from existing work: The most high-profile framing at present focuses on the question how to increase agricultural yields without compromising biodiversity. By contrast, a systems-oriented approach recognizes yield as just one variable alongside others that also influence biodiversity and food security. I will use a multi-scale approach that balances the likely trade-offs between depth and generality. Using a specifically developed typology of social-ecological system properties, I will investigate rural landscapes as social-ecological systems at three levels of detail. First, drawing on expert knowledge, I will develop a global database of at least 50 relevant systems, relating general system properties to indicators of food security and biodiversity. Second, I will conduct in-depth workshops on 15-20 social-ecological systems worldwide to reveal in more detail the causal linkages between system properties, food security and biodiversity. Third, I will conduct an in-depth empirical case study on food security and biodiversity in Ethiopia. This will complement the other components by highlighting the nature of potentially important regional subtleties. My multi-scale approach effectively combines high ambition and high feasibility. SESyP will produce new tools and a holistic theory of relevance to researchers, policy makers, supra-national bodies and non-governmental organizations worldwide.;1788724;1788724;ERC-2013-CoG;/ERC-CG;LEUPHANA UNIVERSITAT LUNEBURG;DE;;;"/REG;/ENV;/SOC";1;0;0;1;0;0 185556;614623;MULTISCOPE;ONG;FP7-IDEAS-ERC;ERC-CG-2013-PE4;FP7;Multidimensional Ultrafast Time-Interferometric Spectroscopy of Coherent Phenomena in all Environments;2014-04-01;2019-03-31;;"'We propose to develop and apply novel methods of nonlinear spectroscopy to investigate the significance and consequences of coherent effects for a variety of photophysical and photochemical molecular processes. We will use coherent two-dimensional (2D) spectroscopy as an ideal tool to study electronic coherences. Quantum mechanics as described by the Schrödinger equation is fully coherent: The phase of a wavefunction evolves deterministically in the time-dependent case. However, observations are restricted to reduced “systems” coupled to an “environment.” The resulting transition from coherent to incoherent behavior on an ultrafast timescale has many yet unexplored consequences, e.g. for transport in photosynthesis, photovoltaics or other molecular “nanomaterials.” In contrast to conventional 2D spectroscopy, we will not measure the coherently emitted field within a four-wave mixing process but rather implement a range of incoherent observables (ion mass spectra, fluorescence, and photoelectrons). Yet we can still extract all the desired information using “phase cycling” with collinear pulse sequences from a femtosecond pulse shaper. This opens up a new range of interdisciplinary experiments and will allow for the first time a direct nonlinear-spectroscopic comparison of molecular systems in all states of matter. Specifically, we will realize 2D spectroscopy in molecular beams, liquids, low-temperature solids, and on surfaces including heterogeneous and nanostructured samples. Tuning the external couplings will help elucidating the role of the environment in electronic (de)coherence phenomena. Furthermore, we will combine 2D spectroscopy with subdiffraction spatial resolution using photoemission electron microscopy (PEEM). This enables us to map transport in molecular aggregates and other heterogeneous nanosystems in time and space on a nanometer length scale. Thus we access the intersection between the domains of electronics and nanophotonics.'";2669124;2669124;ERC-2013-CoG;/ERC-CG;JULIUS-MAXIMILIANS-UNIVERSITAT WURZBURG;DE;;;"/PSE;/SCI";1;0;0;1;0;0 185653;617233;DURACELL;ONG;FP7-IDEAS-ERC;ERC-CG-2013-PE3;FP7;Cell Migration under Mechanical Constraints;2014-06-01;2019-05-31;;"Control of cell migration is crucial for many biological processes. Cells sense mechanical cues to guide their migration. As opposed to passive materials, living cells actively respond to the mechanical stimuli of their environment through the transduction of mechanical information into biochemical signaling events. These responses, particularly to rigidity, include differentiation, migration and alterations in cell-matrix and cell-cell adhesion and thus occur over a wide range of time and length scales. I propose to address the effect of substrate mechanical properties on cell migration using quantitative in vitro methods based on micro-fabrication and micro-mechanical techniques. My main objectives are to: 1/ Discover specific mechanisms that guide single cells toward stiffer substrates (a process known as durotaxis), investigate the range of stiffness-sensitive responses and determine the molecular mechanisms based on actin dynamics and cell adhesion assembly. 2/ Characterize the emergence of coordinated cell movements and thus how cells move in concert under external mechanical constraints. In addition to cell-substrate interactions, the role of cell-cell junctions is crucial in the transmission of mechanical signals over the cell population. By analyzing tissue dynamics at both mesoscopic and molecular scales, we hope to unravel how epithelial cell sheets mechanically integrate multiple adhesive cues to drive collective cell migration.3/ Elucidate the role of 3D mechanical environments in collective cell migration. In contrast to migration in 2D, cells in 3D must overcome the biophysical resistance of their surrounding milieu. Based on optical and innovative micro-fabrication techniques to modify the stiffness of 3D scaffolds, we will study its influence on cell migration modes and invasion. The goal of this interdisciplinary project is to understand how cells integrate mechanical adhesive signals to adapt their internal organization and ensure tissue integrity";1762734;1762734;ERC-2013-CoG;/ERC-CG;UNIVERSITE PARIS DIDEROT - PARIS 7;FR;;;"/PSE;/SCI";1;0;0;1;0;0 185587;615307;QPROGRESS;ONG;FP7-IDEAS-ERC;ERC-CG-2013-PE6;FP7;"""Progress in quantum computing: Algorithms, communication, and applications""";2014-03-01;2019-02-28;;"'Quantum computing combines computer science, physics and mathematics to fundamentally speed up computation using effects from quantum physics. Starting in the early 1980s with Feynman and Deutsch, and gaining momentum in the 1990s with the algorithms of Shor and Grover, this very interdisciplinary area has potentially far reaching consequences. While a large-scale quantum computer has not been built yet, experimenters are getting more optimistic: a recent prediction is that it will take another 10-15 years. However, the tasks where such a quantum computer would be able to significantly outperform classical computers are still quite limited, which lends urgency to finding new applications. This proposal will find more such tasks, and produce new insights into the strengths and weaknesses of quantum computing. It is divided into three workpackages: 1. Algorithms & complexity. Find new quantum algorithms that are more efficient than the best classical algorithms, for example for matrix multiplication and graph problems. Extend our knowledge of the ultimate limitations of quantum algorithms, and possible parallelization (which has barely been studied so far). 2. Quantum communication. Communication complexity analyzes the amount of communication needed to solve distributed computational tasks, where separate parties each hold part of the input. Find new distributed problems where quantum communication outperforms classical communication, and explore links with fundamental physics issues like the role of entanglement and Bell-inequality violations. 3. Classical applications. Apply the newly developed mathematical tools of quantum computing to analyze problems in other areas, as we recently did for linear programs for the traveling salesman problem. This third workpackage will have impact regardless of progress in building a quantum computer. The PI is one of the world’s top researchers in each of these three areas.'";1453700;1453700;ERC-2013-CoG;/ERC-CG;STICHTING CENTRUM VOOR WISKUNDE EN INFORMATICA;NL;;;"/PSE;/ICT;/TEL;/NET";1;0;0;1;0;0 185588;615381;OptoRibo;ONG;FP7-IDEAS-ERC;ERC-CG-2013-LS9;FP7;Optogenetic control of cellular behaviour by allosteric ribonucleic acid assemblies;2014-05-01;2019-04-30;;"Light-sensitive channel proteins have attracted much attention as functional molecules, as they possess unique conformations and functions depending on their respective irradiation states. Embedding these proteins in heterogeneous cellular frameworks enabled to gain light-control of cellular and in particular neuronal behaviour. However to date, optogenetic solutions that address endogenous, intracellular biomolecules in a universal fashion remain elusive. The project will apply design and selection strategies aiming at nucleic acid molecules that can be controlled by irradiation with light and which we have developed in preliminary studies. This will now be taken significant steps forward by generating modular allosteric ribonucleic acid (RNA) assemblies that respond to light. These assemblies provide a generic solution and represent long-sought methods to complement the optogenetic toolbox. The aim of this project is the generation of allosteric molecules built from at least two RNA domains; one domain that binds to a soluble photoreceptor protein (PRP) in a light-dependent manner and a second RNA domain, whose protein inhibiting function in turn depends on the binding state of the PRP-recognizing part. We will construct light-responsive allosteric RNA assemblies that can be ubiquitously used in cells and in vivo, independent of specific model organisms, for optogenetic control and spatiotemporal analysis of endogenous, intracellular biomolecule function. The project is highly interdisciplinary and will open novel routes for biomolecule analysis in cells and in vivo. It has implications ranging from life sciences to optogenetics, and from combinatorial biochemistry to synthetic biology. As these new tools will be applicable by any scientist to analyse protein function at high spatiotemporal resolution, the project bears an enormous innovative potential.";1992438;1992438;ERC-2013-CoG;/ERC-CG;RHEINISCHE FRIEDRICH-WILHELMS-UNIVERSITAT BONN;DE;;;"/BIO;/LIF;/SCI";1;0;0;1;0;0 108063;327695;REAMOFUN;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IIF;FP7;Reactive Molecular Modelling of Multi-Functional Hybrid Graphene/CNT Nanocomposites;2013-10-15;2015-10-14;;'A key research area for composite materials is the addition of nanoscale constituents to provide multi-functionality, i.e. materials capable of meeting multiple demands, such as structural, electrical, thermal, and energy storage. Such materials are termed “multifunctional nanocomposites”. Over the past decade, much research has been performed on carbon nanotube (CNT)-based nanocomposites, and it has been demonstrated that CNTs can enhance the mechanical properties of composites, as well as form conductive networks. More recently, research on graphene-nanoplatelet (GNP) nanocomposites has been undertaken and indications are that GNPs are superior to CNTs for transferring mechanical load. Inspired by the capability of CNTs to form conductive networks and graphene to transfer load, this project will examine hybrid CNT/GNP-reinforced thermoset matrix nanocomposites by large-scale Molecular Dynamics simulations. The objective of this interdisciplinary project is to understand the synergistic mechanisms of GNPs and CNTs in improving mechanical, electrical and thermal properties of hybrid nanocomposites, as demonstrated by a few experiments to date, and to investigate how to design nanocomposites to get optimal performance. In the process, modelling of the in-situ polymerisation of hybrid nanocomposites will be carried out for the first time, and mechanical, electrical and thermal properties of resulting nanocomposites will be predicted. The applicant has published extensively on multi-functional composites and modelling of in-situ polymerisation of polymers, while the Host has 20 years’ experience in composites research in Europe, and is seeking to expand an existing highly-fruitful collaboration with EPFL, Switzerland, in this area. The EU composite community will benefit from the applicant’s unique knowledge and expertise, and the development of an extensible simulation tool for predictive modelling and optimisation of multifunctional thermoset nanocomposites.';254637,8;254637,8;FP7-PEOPLE-2012-IIF;/MC-IIF;UNIVERSITY OF LIMERICK;IE;;;/SCI;1;0;0;1;0;0 104767;306504;TopoMat;ONG;FP7-IDEAS-ERC;ERC-SG-PE5;FP7;Topological insulators: computational exploration of emerging electronic materials;2012-09-01;2017-08-31;;"'Topological insulators are the recently discovered class of materials that have a bulk electronic band gap, but also exhibit conducting surface states as a result of non-trivial band structure topology induced by strong spin-orbit interactions. These peculiar surface states are characterized by a number of novel properties such as graphene-like band dispersion and helical spin textures with no spin degeneracy which makes them immune to scattering. Due to these extraordinary properties, topological insulators are expected to find numerous technological applications, in particular in electronics and its next-day extensions - spintronics and quantum information processing. The project aims at exploring these novel electronic materials in silico; that is, by performing computer simulations using numerical methods of various levels of complexity. The global objective of the proposed research plan is to provide the theoretical support required to build a link between the fundamental physical properties of topological insulators and their prospective technological application by investigating materials science, chemistry and device-related aspects of these materials. In particular, the following three research directions will be explored: (i) understanding the structure-property relations and rational design of new materials with topologically non-trivial electronic structures, (ii) modeling realistic 'second generation' topological insulators (bismuth chalcogenides Bi2Se3, Bi2Te3, and related materials), and (iii) investigating magnetic and transport properties of topological insulators and their interfaces related to the device applications. The proposed interdisciplinary program intends to make a strong impact in basic research and future technologies, and will eventually promote the rapidly expanding field of topological insulators in European science.'";1643997,6;1643997,6;ERC-2012-StG_20111012;/ERC-SG;ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE;CH;;;"/PSE;/IPS;/TEL";1;0;0;1;0;0 107020;327579;G1_G2_NAINHIBIT;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IOF;FP7;Design, synthesis and evaluation of potential group-1 and group-2 neuraminidase inhibitors;2014-01-01;2016-12-31;;"Influenza neuraminidase (NA) is the enzyme that releases influenza virions from the infected cells, cleaving the sialic acid receptor on host cells. It has been recently demonstrated that influenza A has neuraminidase subtypes that belong to two distinct subgroups. The crystal structures of the three subtypes N1, N4 and N8 (group-1 enzymes) were found to be virtually identical in the shapes of their active sites. However they were found to be different when compared to N2 and N9 subtypes (group-2 enzymes). In the case of N1, N4 and N8 subtypes, a loop of amino acids which includes the active site catalytic residue Asp 151, was found to adopt an unusual open conformation compared to the N2 and N9 subtypes in which loop-150 was of a closed conformation. The observation of different active site conformations between certain subtypes of group-1 and group-2 enzymes suggests that these two groups are not only genetically distinct but are also structurally distinct. The main objective of our project is to develop new specific neuraminidase inhibitors with two distinctive important features: 1) a novel general scaffold which provides the correct ring distortion required to mimic both group-1 and group-2 neuraminidase transition-state; 2) further additional groups of suitable shape and size that extend the general structure and fill the cavity-150, with the aim of generate group-1 specific inhibitors. The objectives of the project will be achieved through the employment of multidisciplinary competences, in which the host institutions have enormous experience: design of carbohydrate mimics as inhibitors, libraries synthesis, virus like particles STD-NMR spectroscopy, biological evaluation and molecular modelling.This fellowship will ensure the opportunity for the applicant to be exposed to an international and interdisciplinary context, working on a timely scientific project resulting from the collaboration of two internationally recognized research leaders in glycoscience.";227893,2;227893,2;FP7-PEOPLE-2012-IOF;/MC-IOF;UNIVERSITA DEGLI STUDI DI MILANO;IT;;;/LIF;1;0;0;1;0;0 95993;252915;HISTONESTEM;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IEF;FP7;Histone arginine methylation and citrullination in stem cell maintenance and specification;2010-07-01;2012-06-30;;"Transcription in any given cell type is regulated at the level of chromatin, the complex where all nuclear DNA is packaged together with histones. Post-translational modifications at arginine and lysine residues of histones are key regulators of transcription. Furthermore, histone arginine methylation and citrullination appear to be important in the transcriptional control of several developmental processes. In this project, I intend to investigate the role of histone arginine methylation and citrullination in: (1) the maintenance of the pluri/multipotency status of mouse embryonic stem cells and neural stem cells; (2) the specification of neural stem cells, namely into the oligodendrocyte lineage. Increased understanding of the epigenetic regulation of stem cell fate and oligodendrocyte development is of uttermost importance for the development of cell therapies, in particular for demyelinating diseases. This interdisciplinary project will take advantage of my previously acquired expertise in stem cell biology and neural development, and of the host laboratory’s expertise in epigenetics, chromatin and transcription. I will be using leading-edge techniques such as chromatin immunoprecipitation (ChIP) – sequencing and Stable Isotope Labelling by Aminoacids in Cell culture (SILAC) technology, among others. Thus, this project will allow me to get research training in state-of-the-art techniques in the epigenetics field, which will be essential for my plans to become a principal investigator in the area of epigenetic regulation of neural development, with a focus on oligodendrogenesis.";240289,6;240289,6;FP7-PEOPLE-2009-IEF;/MC-IEF;THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;UK;;;"/SCI;/EDU;/ITT";1;0;0;1;0;0 100615;218108;DHRS-CIM;ONG;FP7-PEOPLE;PEOPLE-2007-3-1-IAPP;FP7;Distributed Human-Robot System for Chemical Incident Management;2008-10-01;2012-09-30;;The overall objective of this project is to combine forces of Europe’s leading industrial (Thales Nederland B.V., Space Application Services N.V., IdMind - Engenharia de Sistemas Lda) and academic organizations (Universities of Sheffield, Amsterdam and Örebro) in the field of ‘Disaster Management’, in order to deliver, through a strategic and intersectoral exchange of researchers, an intelligent decision support system for humans to manage chemical incidents (a Distributed Human-Robot System for Chemical Incident Management or DHRS-CIM). The proposed research deals with human and artificial sensing and sense-making to support human decision making in crisis management. The focus on both artificial- and human-system research in order to integrate both is one of the essential contributions of this research proposal: by doing so the artificial systems and humans together become an intelligent collaborative system. This is highly relevant for Europe as future deployment of such intelligent systems able to detect (potential) chemical incidents, helps crisis professionals take informed decisions to manage chemical incidents. Intersectoral exchange of knowledge will not only lead to (short term) development of innovative technological breakthroughs within this domain, but will also ensure the development of participating researchers towards interdisciplinary scientists needed for research in this (timely) relevant field. Various types of transfer of knowledge are envisioned, such as numerous visits resulting in joint research projects, integration sessions and meetings (e.g. yearly summer schools). Furthermore, structuring effects at the European level are expected by a more structural and strategic future collaboration between the project partners. Finally, the project will contribute to the involvement of two Small and Medium-Sized Enterprises.;1818833;1818833;FP7-PEOPLE-2007-3-1-IAPP;/MC-IAPP;THALES NEDERLAND BV;NL;"SPACE APPLICATIONS SERVICES NV;IDMIND - ENGENHARIA DE SISTEMAS LDA;SHEFFIELD HALLAM UNIVERSITY;OREBRO UNIVERSITY;UNIVERSITEIT VAN AMSTERDAM";"BE;PT;UK;SE;NL";/EDU;1;0;0;1;0;0 100831;269240;SMART-CEA;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-IRSES;FP7;Smart Controlled Environment Agriculture Systems;2011-10-01;2015-05-31;;Half of the European Union's land is farmed. This fact alone highlights the importance of farming for the EU's economy, employment, energy use and environment. In recent years several factors (climate change, unpredictably outside weather conditions, water shortage, energy crisis, environmental pollution) lead to an increase of agriculture production under controlled environments, (CEA) such as greenhouse and livestock buildings. In greenhouse and livestock production, growth practises, techniques, technologies and methodologies should be addressed to the achievement of stated objectives by modifying and improving the relationship of factors involved in the productive process. However the importance of certain objectives can change over time. Currently, several research groups in Europe are engaged in the areas related to the proposed action, but the information and knowledge obtained is dispersed. Moreover, considerable work was carried out in other countries outside from Europe which faced similar problems probably long time ago before the problems become evident in Europe. Many projects, currently being performed in isolation through national funding, will benefit significantly through the action, since it will eliminate overlaps, facilitate collaboration, and make more efficient use of resources, and thus amplify the value of the research for all European stakeholders. The proposed action brings together an international and interdisciplinary group of research teams from Europe, USA & Korea and relative SMEs for the purpose of forming an excellent centre of synergy in research, innovation and technology transfer in the area of agriculture production in greenhouse and livestock buildings aiming to remove the barriers that presently impede a fluent diffusion and actualization of the knowledge and know-how available in the field of new technologies applied to the CEA sector. Focus will be given on climate change, energy, environment and food safety and quality.;210000;210000;FP7-PEOPLE-2010-IRSES;/MC-IRSES;ETHNIKO KENTRO EREVNAS KAI TECHNOLOGIKIS ANAPTYXIS;EL;"AARHUS UNIVERSITET;KENTRO EREVNAS TECHNOLOGIAS KAI ANAPTYXIS THESSALIAS;INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE;STICHTING WAGENINGEN RESEARCH";"DK;EL;FR;NL";"/EMP;/SOC";1;0;0;1;0;0 109359;606795;YEASTCELL;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-ITN;FP7;"Yeast Cell Factories: Training Researchers to Apply Modern Post-Genomic Methods In Yeast Biotechnology";2013-09-01;2017-08-31;;'The YEASTCELL ITN will train 11 Early Stage Researchers for productive careers as research scientists and leaders in the public or private yeast biotechnology sectors. Yeast biotechnology spans fundamental and applied research and is an area with an immediate need for highly trained researchers to advance knowledge and to develop new applications. The training consortium comprises 9 Public Sector (6 Universities, 3 Research Institutes) and 4 Private Sector (2 large companies and 2 SME) partners. A research training programme embracing the philosophy of “use-inspired fundamental research” has been designed to provide all 11 ESRs with interdisciplinary research training in both the public and private sectors. The research themes include yeast physiology and metabolism, metabolic engineering, mathematical modeling, genomics and bioinformatics, fermentation, synthetic biology and systems biology. In addition to training via collaborative research projects, ESRs will participate in courses at local and network levels to enhance their technical and academic skills. All ESRs will register for PhD degrees and will also take a separate postgraduate certificate course in commercialisation and entrepreneurship. Industry-led workshops, research secondments and site visits will provide specific training that prepares ESRs for research in the private sector. A comprehensive programme of advanced training in complementary topics and skills of relevance to both the public and private sectors is provided at the network level. As well as directly training 11 ESRs, the network training activities will provide opportunities for ~40 additional researchers and will promote long-term interactions between research groups at the partner Institutions. The major impact of YEASTCELL will be a cohort of highly-trained ESRs with excellent career prospects in the yeast biotechnology sector and a lasting European training and research collaboration between public and private sector partners.';3066365,28;3066365,28;FP7-PEOPLE-2013-ITN;/MC-ITN;UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK;IE;"UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN;LEIBNIZ - INSTITUT FUER PFLANZENGENETIK UND KULTURPFLANZENFORSCHUNG;Teknologian tutkimuskeskus VTT Oy;EVOLVA BIOTECH A/S;JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN;LALLEMAND SAS;UNIVERSITA' DEGLI STUDI DI MILANO-BICOCCA;INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE;TEKNOLOGIAN TUTKIMUSKESKUS VTT;TECHNISCHE UNIVERSITEIT DELFT;CHALMERS TEKNISKA HOEGSKOLA AB";"IE;DE;FI;DK;FR;IT;NL;SE";/LIF;1;0;0;1;0;0 108546;327985;TRXTERMSIGN;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IEF;FP7;Genetic and epigenetic signature of transcription termination;2014-01-02;2016-07-24;;"Most eukaryotic genes are transcribed by RNA polymerase II (Pol II) in a cycle of initiation, elongation and termination. Transcription termination, defined as the cessation of RNA synthesis and release of Pol II from its DNA template, depends on a functional poly(A) sequence as well as downstream terminator sequences. Correct termination is important for the prevention of transcriptional interference, efficient protein production and Pol II recycling. Further on, aberrant poly(A) usage and alterations of 3' UTR length have been functionally linked to cancer. Despite its vital importance, transcription termination mechanisms have only been studied on a handful of genes, and the general principles ruling this process are unknown. In particular, the influence of the chromatin context on Pol II termination is an enigma. The objective of this proposal is to elucidate the genetic and epigenetic signature of transcription termination genome-wide using a combination of computational, genetic and biochemical approaches. First, a systematic in silico screening will be performed for chromatin modifications and transcription factors' occupancy, as well as DNA sequence elements in putative terminator regions. It will be based on the model genes and their termination pathways dissected in the host lab, as well as a wide range of publicly available and self-generated genome-wide data sets of chromatin-associated features. This unbiased screening will yield the first insight into the genome-wide characteristics (signature) of terminator elements, allowing for subsequent functional studies using hypothesis-driven experimental approaches. The implementation of this proposal will strongly enhance the researcher's competence by training in the field of RNA processing, complementary to her background in chromatin biology and bioinformatics, foster the development of her interdisciplinary skills and ultimately support her in attaining a future group leader position.";231283,2;231283,2;FP7-PEOPLE-2012-IEF;/MC-IEF;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;UK;;;/SCI;1;0;0;1;0;0 106871;318911;EU-PREACC;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IRSES;FP7;Possibilities and limits, challenges and obstacles of transferring CEE EU pre-accession best practices and experience to Moldova’s and Georgia's pre-accession process;2013-03-01;2017-02-28;;"The research will cover areas of the EU-Moldova and EU-Georgia cooperation, linked to both, the European Neighbourhood Policy Action Plan and the EU conditionality. It looks at Moldova’s and Georgia's economic, legal and political situation and development. The focus of the project and project-related research is structuring the CEE states' reform experience and analysing the possibilities and limits of transferring the best practices and experience to Moldova’s and Georgia's (possible) EU pre-accession process. It analyses the situation in Moldova and Georgia and suggests benchmarking opportunities best suitable for Moldova and Georgia. The results of the analysis and researchers/lecturers exchange are wrapped up via regular thematic workshops and publications. The output of the research results is also used in improving and developing the European Union-related curricula and courses in all participating universites: in Tartu, Vilnius, Moldova and Georgia. Work Packages are as follows: 1. Mapping CEE states' reform experience: environment of positive conditionality – mapping of success and failure of reforms in key policy areas related to EU accession criteria (Progress Report Chapters); 2. European Neighbourhood Policy and Europeanization (political, economic and legal aspects) – analysing which CEE states' pre-accession knowledge is transferable and needed; 3. Moldova and Georgia – the transition countries on the EU border and states between EU and Russia – analysing the specific circumstances and policy trends; 4. Teaching EU, EU-Russia relations and European Neighbourhood Policy in the context of interdisciplinary European Studies curricula.";589000;589000;FP7-PEOPLE-2012-IRSES;/MC-IRSES;TARTU ULIKOOL;EE;"UNIVERSITATEA DE STAT DIN MOLDOVA;VILNIAUS UNIVERSITETAS";"MD;LT";/SCI;1;0;0;1;0;0 102018;290098;NEWGENPAK;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-ITN;FP7;New Generation of Functional Cellulose Fibre Based Packaging Materials for Sustainability;2011-12-01;2015-11-30;http://www.newgenpak.eu/;"The NEWGENPAK ITN is an interdisciplinary research training network of 8 European universities, 3 research institutes and 6 enterprises, three of which are Full partners. Its primary aim is to create a European training network designed to improve the career prospects of its 10 ESRs and 2 ERs in both the public and private sector. The network will deliver a joint multidisciplinary research training programme which will encourage and foster the growth of the researchers’ skills in scientific expertise, technological knowledge and professional aptitude. The key vehicle in this strategy is a supervised personal, original research project in a critical aspect of sustainable packaging. The network has been designed to achieve the following objectives (i) to conduct top-level research and training and devise innovative solutions for specific EU needs in the area of sustainable packaging, (ii) to advance the state-of-the-art in wood cellulose based sustainable packaging in three specific areas (a) next generation packaging composites, (b) cellulose-fibre based active packaging and (c) environmental, economic and societal aspects of packaging production, (iii) to educate the next generation of researchers inside a broad European research training network which includes universities, research centres and industry, thereby accelerating the researchers’ advancement to team leader status, (iv) to improve the career prospects of ERs and ESRs through complementary training such as; writing and presentation skills; language, effective communication and collaboration; project management and finance; project/product cycles; entrepreneurship; IPR, (v) to create an integrated, long-term sustainable packaging research and training base in the EU by bringing together universities, research institutes and industrial players active in key research disciplines.";3190329,03;3190329,03;FP7-PEOPLE-2011-ITN;/MC-ITN;SHEFFIELD HALLAM UNIVERSITY;UK;"INSTITUTO TECNOLOGICO DEL EMBALAJE, TRANSPORTE Y LOGISTICA;AZIENDA SPECIALE INNOVHUB - STAZIONI SPERIMENTALI PER L'INDUSTRIA;INSTITUT POLYTECHNIQUE DE GRENOBLE;MULTI PACKAGING SOLUTIONS UK LIMITED;IMERYS MINERALS LTD;DANMARKS TEKNISKE UNIVERSITET;PAPIERTECHNISCHE STIFTUNG;ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA;BUMAGA BV;KARLSTADS UNIVERSITET;ZACHODNIOPOMORSKI UNIWERSYTET TECHNOLOGICZNY W SZCZECINIE";"ES;IT;FR;UK;DK;DE;NL;SE;PL";"/LIF;/SCI";1;0;0;1;0;0 104615;307036;SCADAPT;ONG;FP7-IDEAS-ERC;ERC-SG-PE6;FP7;"""Large-scale Adaptive Sensing, Learning and Decision Making: Theory and Applications""";2012-11-01;2017-10-31;;"'We address one of the fundamental challenges of our time: Acting effectively while facing a deluge of data. Massive volumes of data are generated from corporate and public sources every second, in social, scientific and commercial applications. In addition, more and more low level sensor devices are becoming available and accessible, potentially to the benefit of myriads of applications. However, access to the data is limited, due to computational, bandwidth, power and other limitations. Crucially, simply gathering data is not enough: we need to make decisions based on the information we obtain. Thus, one of the key problems is: How can we obtain most decision-relevant information at minimum cost? Most existing techniques are either heuristics with no guarantees, or do not scale to large problems. We recently showed that many information gathering problems satisfy submodularity, an intuitive diminishing returns condition. Its exploitation allowed us to develop algorithms with strong guarantees and empirical performance. However, existing algorithms are limited: they cannot cope with dynamic phenomena that change over time, are inherently centralized and thus do not scale with modern, distributed computing paradigms. Perhaps most crucially, they have been designed with the focus of gathering data, but not for making decisions based on this data. We seek to substantially advance large-scale adaptive decision making under partial observability, by grounding it in the novel computational framework of adaptive submodular optimization. We will develop fundamentally new scalable techniques bridging statistical learning, combinatorial optimization, probabilistic inference and decision theory to overcome the limitations of existing methods. In addition to developing novel theory and algorithms, we will demonstrate the performance of our methods on challenging real world interdisciplinary problems in community sensing, information retrieval and computational sustainability.'";1499900;1499900;ERC-2012-StG_20111012;/ERC-SG;EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH;CH;;;"/PSE;/IPS";1;0;0;1;0;0 92151;235418;SOLAIROS;ONG;FP7-PEOPLE;FP7-PEOPLE-IOF-2008;FP7;Solubility of Aerosol Iron in Open-ocean Seawater;2009-11-01;2012-10-31;;The distribution of iron in the oceans is known to have a significant impact on carbon and nitrogen biogeochemical cycles and climate variability due to its role as a growth limiting nutrient for phytoplankton. The principle mechanism for iron transport to remote open ocean surface water is via the atmospheric transport of aerosol material. Hence an accurate understanding of the controlling variables for dissolution of aerosol iron in seawater is required to advance and improve global biogeochemical models. The aim of the proposed work is to conduct a rigorous study of aerosol iron dissolution in seawater by mimicking the conditions and variables of the air/sea interface that will affect the process. The study will test the hypothesis that the physico-chemical nature of seawater controls this dissolution process rather than the nature of the aerosol deposited. To address this, ship-board and laboratory dissolution experiments will be conducted following the collection and characterisation of aerosol and seawater samples from the Bermuda Atlantic Time Series region. The project will be based at the Bermuda Institute of Ocean Sciences (BIOS) and at the University of Plymouth (UoP) host institutions. The collaborative work will benefit the EU scientific community and strengthen the researcher’s profile by offering high level training in atmospheric sampling and handling and a variety of analytical techniques for the determination of dissolved iron species in seawater. It will also allow continued and frequent access to open ocean seawater and aerosol samples as well as interdisciplinary training in meteorology, oceanography and remote sensing. The results from the study will further contribute to the international scientific community by better constraining iron transport for global biogeochemical models and improving predictions of the effects of climate change, ocean acidification, anthropogenic emissions and modifications to land use and vegetation.;244807,84;244807,84;FP7-PEOPLE-IOF-2008;/MC-IOF;UNIVERSITY OF PLYMOUTH;UK;;;"/COO;/EDU";1;0;0;1;0;0 98322;258813;COMPLEXDATA;ONG;FP7-IDEAS-ERC;ERC-SG-PE1;FP7;Statistics for Complex Data: Understanding Randomness, Geometry and Complexity with a view Towards Biophysics;2011-06-01;2016-05-31;;The ComplexData project aims at advancing our understanding of the statistical treatment of varied types of complex data by generating new theory and methods, and to obtain progress in concrete current biophysical problems through the implementation of the new tools developed. Complex Data constitute data where the basic object of observation cannot be described in the standard Euclidean context of statistics, but rather needs to be thought of as an element of an abstract mathematical space with special properties. Scientific progress has, in recent years, begun to generate an increasing number of new and complex types of data that require statistical understanding and analysis. Four such types of data that are arising in the context of current scientific research and that the project will be focusing on are: random integral transforms, random unlabelled shapes, random flows of functions, and random tensor fields. In these unconventional contexts for statistics, the strategy of the project will be to carefully exploit the special aspects involved due to geometry, dimension and randomness in order to be able to either adapt and synthesize existing statistical methods, or to generate new statistical ideas altogether. However, the project will not restrict itself to merely studying the theoretical aspects of complex data, but will be truly interdisciplinary. The connecting thread among all the above data types is that their study is motivated by, and will be applied to concrete practical problems arising in the study of biological structure, dynamics, and function: biophysics. For this reason, the programme will be in interaction with local and international contacts from this field. In particular, the theoretical/methodological output of the four programme research foci will be applied to gain insights in the following corresponding four application areas: electron microscopy, protein homology, DNA molecular dynamics, brain imaging.;681145,6;681145,6;ERC-2010-StG_20091028;/ERC-SG;ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE;CH;;;"/PSE;/MST";1;0;0;1;0;0 102030;267194;COFUND-CERN-2010;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-COFUND;FP7;COFUNDing of the CERN Fellowship Programme 2010;2011-10-01;2015-09-30;;"For many years, CERN has operated a trans-national Fellowship programme, offering scientists and engineers challenging opportunities in particle physics research, and in related fields of physics and technology. The COFUND action offers CERN a timely opportunity to enhance the mobility element of this programme, which is open to nationals of all countries. This opportunity comes at a time when the startup of the Large Hadron Collider makes CERN one of the most exciting places to work for the global physics and technology community. Mobility will be enhanced through the opportunity to spend up to one third of the Fellowship in external institutions, including industrial laboratories. The employment conditions will be improved by offering three-year appointments rather than the standard two-year terms of CERN Fellows. These improvements, enabled by the COFUND action, will further increase the competitiveness of CERN’s Fellowship Programme. In particular, they are expected to trigger a strong reintegration effect on European researchers presently based in the US. Applicants will propose their own research projects. Selection will be based on the scientific potential of the proposal, and on the demonstrated excellence of the candidate. Working on frontier research and technology projects and profiting from the unique facilities available at CERN, the co-funded Fellows will deepen their knowledge in their own field and acquire international visibility and reputation. They will broaden their skills using the numerous training opportunities and through their exposure to an interdisciplinary and multi-national environment. Inter-sectorial skills will be fostered through CERN’s industrial collaborations and technology transfer projects. Fellows will spend at least two thirds of their Fellowship at CERN. This provision is justified by the size of the Laboratory, the diversity of the research and training opportunities, and by the uniqueness of CERN’s facilities.";12499104;4999641,6;FP7-PEOPLE-2010-COFUND;/MC-COFUND;EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH;CH;;;"/SOC;/COO;/NET";1;0;0;1;0;0 106868;309064;VIR4ENV;ONG;FP7-IDEAS-ERC;ERC-SG-LS6;FP7;Virulence factors of facultative pathogens and their role outside the human host;2013-02-01;2018-01-31;;"'The etiologic agent of cholera, Vibrio cholerae, is an important cause of human morbidity and mortality, particularly in developing countries or following environmental disasters. The watery diarrhea characteristic of cholera results from the action of bacterial virulence determinants, notably cholera toxin, which gene has been acquired by horizontal gene transfer. V. cholerae as a facultative pathogen commonly occurs in aquatic ecosystems, its true habitat, where it intimately associates with phyto- and zooplankton. My proposal will investigate intensively the interaction between V. cholerae and non-vertebrate animals in marine environments and test the hypothesis that virulence determinants important in human disease are also critical for colonization of these environmental hosts. There are three interlinked specific aims: Aim 1: Establish microcosms involving V. cholerae and its environmental hosts. Aim 2: Identify factors that are beneficial for both lifestyles of V. cholerae. Aim 3: Determine the role of known virulence factors in nature. There is growing concern about the (re-)emergence of infectious agents and the threat this poses to human health particularly in the context of climate change. The sporadic and unpredictable nature of cholera epidemics has long puzzled environmental microbiologists. The interdisciplinary research proposed in this study will provide the missing link between the ecology and evolution of V. cholerae on the one hand and its pathogenesis on the other. Knowledge of how an innocuous microbe in an aquatic environment can become a major human pathogen and identification of the factors responsible are both of considerable importance.'";1698924;1698924;ERC-2012-StG_20111109;/ERC-SG;ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE;CH;;;"/BIO;/LIF;/MED";1;0;0;1;0;0 110153;612338;DNA-TRAP;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IAPP;FP7;DNA-TRAP – Delivery of Nucleic Acid-Based Therapeutics for the TReatment of Antibiotic-Resistant Pathogens;2013-10-01;2017-09-30;;"Antimicrobial agents, such as antibiotics, have dramatically reduced the number of deaths from infectious diseases over the last 70 years. However, through overuse and misuse of these agents, many micro-organisms have developed antimicrobial resistance. Oligonucleotide therapeutics have the potential to become the new class of antibacterials capable of treating a broad range of infections. By acting on novel targets, they circumvent current resistance mechanisms and with judicious use, can suppress the rise of future resistance. DNA-TRAP will build on a platform technology that uses proprietary nucleic acid-based Transcription Factor Decoys (TFDs) that act on novel genomic targets by capturing key regulatory proteins to block essential bacterial genes and defeat infection. Taking forward newly emerging insights and expertise that exists within each of the partners and through the mutual secondment of researchers, the project aims to develop a new class of nanoparticulate antibacterials capable of meeting the clinical challenge of drug-resistant infections such as Clostridium difficile and Pseudomonas aeruginosa. DNA-TRAP will establish a lasting, international partnership for transfer of knowledge between Industry and Academia in the field of nanomedicine. Exchange of knowledge and expertise between the partners is key to establishing the fundamental properties of nanostructured drug delivery systems to treat bacterial infections and through this, provide the basis for building a manufacturing platform to advance the experimental therapeutic into clinical trials. 17 researchers in the field of drug development and delivery from 2 commercial (SME) and 2 non-commercial partners across 2 member states, will have the opportunity to share and acquire new complementary and multidisciplinary knowledge, through inter-sectoral and interdisciplinary exchange, allowing for the development of new solutions and the establishment of further joint research projects.";2371031;2371031;FP7-PEOPLE-2013-IAPP;/MC-IAPP;UNIVERSITY OF EAST ANGLIA;UK;"KUECEPT LIMITED;TECREA LIMITED;PROCARTA BIOSYSTEMS LIMITED;CONSORZIO INTERUNIVERSITARIO PER LO SVILUPPO DEI SISTEMI A GRANDE INTERFASE;NANOVECTOR SRL";"UK;IT";/LIF;1;0;0;1;0;0 110763;340328;MECCA;ONG;FP7-IDEAS-ERC;ERC-AG-PE6;FP7;Meeting Challenges in Computer Architecture;2014-02-01;2019-01-31;;"'Computer technology has doubled computational performance every 24 months, over the past several decades. This performance growth rate has been an enabler for the dramatic innovation in information technology that now embraces our society. Before 2004, application developers could exploit this performance growth rate with no effort. However, since 2004 power consumption of computer chips exceeded the allowable limits and from that point and onwards, parallel computer architectures became the norm. Currently, parallelism is completely exposed to application developers and managing it is difficult and time-consuming. This has a serious impact on software productivity that may stall progress in information technology. Technology forecasts predict that by 2020 there will be hundreds of processors on a computer chip. Apart from managing parallelism, keeping power consumption within allowable limits will remain a key roadblock for maintaining historical performance growth rates. Power efficiency must increase by an order of magnitude in the next ten years to not limit the growth rate. Finally, computer chips are also key components in embedded controllers, where stringent timing responses are mandatory. Delivering predictable and tight response times using parallel architectures is a challenging and unsolved problem. MECCA takes a novel, interdisciplinary and unconventional approach to address three important challenges facing computer architecture – the three Ps: Parallelism, Power, and Predictability in a unified framework. Unlike earlier, predominantly disciplinary approaches, MECCA bridges layers in computing systems from the programming language/model, to the compiler, to the run-time/OS, down to the architecture layer. This opens up for exchanging information across layers to manage parallelism and architectural resources in a transparent way to application developers to meet challenging performance, power, and predictability requirements for future computers.'";2379822;2379822;ERC-2013-ADG;/ERC-AG;CHALMERS TEKNISKA HOEGSKOLA AB;SE;;;"/PSE;/ICT;/TEL;/NET";1;0;0;1;0;0 108320;329574;YXY FS;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IEF;FP7;Producing YXY FUELS from C6 carbohydrates using nanomaterials;2014-01-15;2016-01-14;;"'The urgency to identify and develop sustainable and timely solutions for our future society has become clearly demonstrated due to the alarming trends in global energy demand, the finite nature of fossil fuel reserves, the need to dramatically curb emissions of greenhouse gases to mitigate the devastating consequences of climate change, the damaging volatility of oil prices (in particular for the transport sector) and the geopolitical instability in supplier regions. In this regard, I started to work since my postgraduated studies in to find alternative and greener methodologies in terms of materials preparation, production of biofuels (which can partially meet the future expected needs of our society in terms of energy for transport), (photo)catalysis as a greener alternative for the production of chemicals and energy as well as biomass and waste valorisation. Biomass from plant is the most important feedstock for food, feed and non-food applications. In the processing of plant materials e.g. wood for paper, substantial amounts of potentially valuable by-products are produced. In this regard, the host organisation, Avantium Chemicals BV, explores unique bio-refinery concepts on novel routes for C6 carbohydrates conversion using nanomaterials. The main objectives are: 1)To develop a range of new multifunctional catalysts (e.g. based on mesoporous silica materials with controlled acidity and metal nanoparticles loading), through synthesis, using a combination of novel techniques 2)To screen their reactivity using model reactions 3)To develop an approach for testing selected catalysts using real feeds from e. g. the pilot plant 4)To optimise the reaction conditions (with emphasis on the reduction of energy consumption aand waste production), evaluation of the catalyst stability. 5)To integrate my knowledge and experience in heterogeneous catalysis into the Avantium R&D environment. In order to achieve these ambitious goals, I will use an interdisciplinary approach.'";183469,8;183469,8;FP7-PEOPLE-2012-IEF;/MC-IEF;AVANTIUM CHEMICALS BV;NL;;;/SCI;1;0;0;1;0;0 109855;606570;NANOFOOT;ONG;FP7-SME;SME-2013-1;FP7;Materials, Components and Footwear with enhanced comfort properties based on nanotechnologies;2013-09-01;2015-08-31;;"NANOFOOT main goal is to develop advanced and innovative nanotechnology based solutions for leathers and polymers components for footwear products, aiming a new sustainable and customer-driven production of consumer goods; where the health, environment, high quality of components, fair marketing communication and competitive sales price are combined to promote the competitiveness of the companies. NANOFOOT SMEs have the ambition of exploring the potentialities and the benefits of nanoparticles (NPs) available in the market on the development of new functional materials & products. The final objective is to get differentiated, high added value and marketable materials and footwear consumer goods; that satisfy the needs and expectations of the final consumers. The consortium is constituted by 9 members (5 SMEs and 4 RTD institutions). A balanced and interdisciplinary team is formed by combining the know-how of SMEs with the expertise of the University and Technology Research Centres. The consortium will provide an effective way to develop and transfer knowledge to the companies, a requisite needed to promote innovation and the results commercial exploitation. NANOFOOT RTD and technical activities include: Screening of commercially available cost-effective nanoparticles; • Investigation of the functionalization of processing products, coatings and leathers using nanoparticles. • Investigation and development of polymeric nanocomposites and footwear components. • Develop advanced antimicrobial thermal auto-regulated footwear. • Develop an integrated environmental approach to safeguard consumers, workers, workplace and environmental. • Perform prototype demonstrators and dissemination actions. • Prepare results exploitation by the SMEs and IPR protection.";846318,32;622000;FP7-SME-2013;/BSG-SME;CURTUMES AVENEDA LDA;PT;"TODO PARA SUS PIES SL;CAMMINALEGGERO DI PINI CAROLINA;CENTRO TECNOLOGICO DE CALCADO DE PORTUGAL;INDINOR-INDUSTRIAS QUIMICAS SA;INSTITUTO TECNOLOGICO DEL CALZADO Y CONEXAS;CONSIGLIO NAZIONALE DELLE RICERCHE;UNIVERSIDADE DO PORTO;EVATHINK S.L.";"ES;IT;PT";/REG;1;0;0;1;0;0 105909;314254;NEAR2;ONG;FP7-TRANSPORT;SST.2012.2.5-2.;FP7;Network of European – Asian Rail Research capacities;2012-12-01;2014-11-30;;"The rapid development of Asian economies, particularly China, India and Russia has dramatically increased the trade volumes between Europe and Asia, with the largest trading partners of Europe actually being located in Asia. Nowadays, the most important trade loads are being transported between the two continents by sea. Railway transport, using the existing and new land routes for the Trans-Eurasian land bridge presents a viable alternative to the maritime routes, which is gaining significant momentum. Due to the origins and current nature of this rail land bridge, numerous issues need to be resolved to bring the system to a modern state of infrastructure, services and operations. Furthermore, to build the capacity to fully exploit the systems potential adaptation of new technologies, interoperability solutions and optimized operations should be considered. To support this objective, NEAR2 proposed the development of a Rail Research Network, drawing knowledge and expertise form leading institutions and researchers from both continents. The project capitalizes upon the existing structure and leverages the achievements of the existing European Rail Research Network and builds upon the reservoir of expertise of the proposed project partners gleaned from the most relevant past and on going research projects and other activities. The Network aims to become the resource arm of the relevant industry. NEAR2 will establish a unique, international, interdisciplinary research capacity with the goal of contributing in advancing a major sector of the regions’ economy, as well as broaden the knowledge basis of the railway research and practice.";962831,9;887003;FP7-SST-2012-RTD-1;/CSA-CA;ETHNIKO KENTRO EREVNAS KAI TECHNOLOGIKIS ANAPTYXIS;EL;"INSTYTUT KOLEJNICTWA;EURNEX e. V.;TONGJI UNIVERSITY;A-TRANS LLC;TECHNISCHE UNIVERSITAET BERLIN;TRAINOSE METAFORES-METAFORIKES YPIRESIES EPIVATON KAI FORTIOU AE;CESKE VYSOKE UCENI TECHNICKE V PRAZE;EIRC Consulting Private Limited;Moscow State University of Railway Engineering;VILNIAUS GEDIMINO TECHNIKOS UNIVERSITETAS;STATE HIGHER EDUCATIONAL ESTABLISHMENT DONETSK RAILWAY TRANSPORT INSTITUTE OF UKRAINIAN STATE ACADEMY OF RAILWAY TRANSPORT;Petersburg State Transport University";"PL;DE;CN;RU;EL;CZ;IN;LT;UA";/SCI;1;0;0;1;0;0 109150;608062;PICQUE;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-ITN;FP7;Photonic Integrated Compound Quantum Encoding;2013-09-01;2017-08-31;;"'Quantum information was born from the merging of information science and quantum physics. Its main objective consists of harnessing the quantum nature of information and learning how to process it by using physical systems operating according quantum mechanics laws. Being supported by numerous proofs-of-principle, the field is now ready to proceed to move to the next level of applications, where several quantum bits are interfaced. This includes quantum simulation, quantum chemistry, to quantum cryptography and quantum sensing. For this purpose, integrated photonic circuits have a strong potential to implement quantum information processing in optical systems. Europe has built a unique world-wide leading position in this area, hosting almost all the world-leading groups in this field which constitute the core of this international training network. Realizing the promise of “Integrated Quantum Photonics” now requires research and training not only in quantum physics and quantum optics, but also in photonics engineering, and material science. PICQUE is at the core of European technological innovation. Excellence in science is guaranteed by the involvement of world-leading groups which founded this research area. All the basic components of a photonic quantum processor will be addressed: generation, manipulation and detection of photon states. Particular attention will be devoted to potential applications and on how to interface all the different components PICQUE will establish a world-class training platform spreading around the highly interdisciplinar y/inter-sectorial European-led area of quantum integrated photonics. By pushing the development of quantum optical technologies we foresee results of interest also for standard optical technologies. PICQUE will aims at forming the new generation of quantum information scientists, as well as figures being able to interact with the industry.'";3972237,5;3972237,5;FP7-PEOPLE-2013-ITN;/MC-ITN;UNIVERSITA DEGLI STUDI DI ROMA LA SAPIENZA;IT;"UNIVERSITAT WIEN;Friedrich Schiller University Jena;CONSIGLIO NAZIONALE DELLE RICERCHE;TOSHIBA RESEARCH EUROPE LIMITED;UNIVERSITY OF BRISTOL;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;TECHNISCHE UNIVERSITEIT EINDHOVEN;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;UNIVERSITAET PADERBORN";"AT;DE;IT;UK;NL;FR";/LIF;1;0;0;1;0;0 94524;234847;STRING MODELS;ONG;FP7-PEOPLE;FP7-PEOPLE-IIF-2008;FP7;Realistic Local Models in Moduli Stabilised String Compactifications;2010-04-01;2012-03-31;;"String theory has the promise to provide answers for many of the puzzles in our current understanding of particle physics and cosmology. In string theory, space time has ten dimensions; four of them corresponding to the dimensions we observe, the six extra dimensions are curled up at an unobservable scale (compactified). One of the long standing problems in string theory was that known solutions for the internal dimension had continuous degeneracies (size and shape of extra dimensions). This predicted massless scalars for our four dimensional universe; in contradiction with observations. Furthermore, this continuous degeneracy implied that the parameters of the standard model - gauge couplings, fermion masses etc., could not be determined. One of the important developments in recent years is the discovery of solutions in which the size and shape of the extra dimensions are fixed (moduli stabilization). Thus we are now in a position to construct and explicitly analyze models of particle physics and cosmology derived from string theory. The project will aim to construct phenomenologically realistic models in this setting. We shall focus on models in which the standard model of particle physics (SM) is localized at a certain singularity in the extra dimension. Many issues of the physics of the SM will be addressed by a local model at the singularity, we shall then attempt at consistent embedding of the local model in a compactification which also gives the ``correct" cosmology. We plan to take advantage of recent advances in numerical methods for algebaric geometry to answer various questions considered intractable in the past. The project shall involve interdisciplinary activity in the area of string theory, particle physics, cosmology, algebraic geometry and computational computer science. It will also receive guidance from state of art experiments, the large hadron collider (LHC) at CERN and the PLANCK satellite.";;164269,69;FP7-PEOPLE-IIF-2008;/MC-IIF;THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;UK;;;"/SCI;/EMP";1;0;0;1;0;0 96973;264474;MERIT;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-ITN;FP7;Metabolic Reprogramming by Induction of Transcription;2011-01-01;2014-12-31;;"Plants continually monitor the environment to modify physiology and development at the molecular level to ensure maximal fitness. Central in the signaling network is the SnRK1 kinases (homologous to AMPK and SNF1 in mammals and yeast respectively). These kinases are vital to the energy balance of the organism and regulate primary metabolism by controlling transcription factors, which control the expression of genes encoding key enzymes. SnRK1 signaling and reprogrammed metabolism have turned out to be crucial for establishments of tolerance and sustained growth during stress. This proposal suggests a multilevel approach to signaling in which all levels of the signal transduction pathway are addressed. The proposal is truly interdisciplinary and a wide range of methodology will be deployed ranging from classical physiology to state-of-the-art mass spectrometry based protein and metabolite profiling, massive sequencing of immuno-precipitated chromatin and whole genome expression profiling. This will be further supported by bioinformatic approaches, phylogenetical as well as network based. The aim is to understand the mechanisms regulating energy balance in plants and their impact on plant performance under stress. Improved stress tolerance of plants is of strategic importance in a world with rising population and changing climate. This strategic importance as well as future recruitment possibilities motivates the high involvement of industrial partners in the proposed activities. The proposed training activities will coach future top-performers for professional career in the biotech industry as well as in the academia. The training program includes network-wide workshops (methodology, industry relevant skills and more) as well as structured local training in the host institutions. Important is a rich schedule of secondments in witch the young researchers will learn new technologies, widen their scientific horizons and establish their academic networks.";2883270;2883270;FP7-PEOPLE-2010-ITN;/MC-ITN;UNIVERSITEIT UTRECHT;NL;"UNIVERSITAT WIEN;FUNDACAO CALOUSTE GULBENKIAN;BAYER CROPSCIENCE NV;BAYER BIOSCIENCE NV;EBERHARD KARLS UNIVERSITAET TUEBINGEN;JULIUS-MAXIMILIANS-UNIVERSITAT WURZBURG;UNIVERSIDAD POLITECNICA DE MADRID";"AT;PT;BE;DE;ES";"/EDU;/NET";1;0;0;1;0;0 109933;612547;FUEGO;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IRSES;FP7;Global Network of Excellence for Research on Adipose Tissue Plasticity and Human Thermogenesis;2013-09-01;2017-08-31;;'Our aim is to create a multiannual joint programme dedicated to exchanges of research staff between European (Sweden, Greece, UK) research entities and other third countries (Brazil, Belarus, and In-dia) to increase knowledge on adipose tissue plasticity and human thermogenesis. The proposal stems from recent reports suggesting that mammalian adipose tissue has the ability to alter its structure and phenotype depending on the environmental or physiological situation (e.g. cold exposure or exercise). If this is confirmed, it will have important implications regarding overall metabolic rate, body weight regulation, and cardio-metabolic disease in humans. The project is designed to exploit the complimentary expertise of EU and third country research or-ganisations through knowledge sharing and transfer between countries. This will be achieved by establishing a Network of Excellence (NoE) that will incorporate staff secondments for the purpose of networking, training activities, workshops, and joint research. Thus, this proposal will foster a mutual understanding of the different disciplines, encouraging entrepreneurship and long-term interdisciplinary collaboration regarding adipose tissue plasticity and human thermogenesis.';404400;404400;FP7-PEOPLE-2013-IRSES;/MC-IRSES;ETHNIKO KENTRO EREVNAS KAI TECHNOLOGIKIS ANAPTYXIS;EL;"UNIVERSITY OF WOLVERHAMPTON;GOETEBORGS UNIVERSITET";"UK;SE";/LIF;1;0;0;1;0;0 110932;335090;AGESPACE;ONG;FP7-IDEAS-ERC;ERC-SG-SH4;FP7;SPATIAL NAVIGATION – A UNIQUE WINDOW INTO MECHANISMS OF COGNITIVE AGEING;2014-01-01;2018-12-31;;"'By 2040, the European population aged over 60 will rise to 290 million, with those estimated to have dementia to 15.9 million. These dramatic demographic changes will pose huge challenges to health care systems, hence a detailed understanding of age-related cognitive and neurobiological changes is essential for helping elderly populations maintain independence. However, while existing research into cognitive ageing has carefully characterised developmental trajectories of functions such as memory and processing speed, one key cognitive ability that is particularly relevant to everyday functioning has received very little attention: In surveys, elderly people often report substantial declines in navigational abilities such as problems with finding one’s way in a novel environment. Such deficits severely restrict the mobility of elderly people and affect physical activity and social participation, but the underlying behavioural and neuronal mechanisms are poorly understood. In this proposal, I will take a new approach to cognitive ageing that will bridge the gap between animal neurobiology and human cognitive neuroscience. With support from the ERC, I will create a team that will characterise the mechanisms mediating age-related changes in navigational processing in humans. The project will focus on three structures that perform key computations for spatial navigation, form a closely interconnected triadic network, and are particularly sensitive to the ageing process. Crucially, the team will employ an interdisciplinary methodological approach that combines mathematical modelling, brain imaging and innovative data analysis techniques with novel virtual environment technology, which allows for rigorous testing of predictions derived from animal findings. Finally, the proposal also incorporates a translational project aimed at improving spatial mnemonic functioning with a behavioural intervention, which provides a direct test of functional relevance and societal impact.'";1318990;1318990;ERC-2013-StG;/ERC-SG;DEUTSCHES ZENTRUM FUR NEURODEGENERATIVE ERKRANKUNGEN EV;DE;;;/SOC;1;0;0;1;0;0 105496;319054;NANOEIS;ONG;FP7-NMP;NMP.2012.1.4-5;FP7;Nanotechnology Education for Industry and Society;2012-11-01;2015-10-31;http://www.nanoeis.eu/;Nanotechnology is an emerging area with strong implications for European society and industry. It is a challenge for the education system to integrate this interdisciplinary and transsectoral subject into curricula shaped mostly along classical disciplines. NanoEIS will evaluate how nanotechnology education has been integrated into secondary schools and universities, how cooperations between different partner institutions were implemented, and in which ways industrial and non-industrial (social) employers have been involved. NanoEIS will make, based on a thorough assessment of employer needs, recommendations for curriculum contents as well as for best practice strategies to implement them. This will help to resolve the problem that education contents are not always well matched with the needs of the job market. Improving this situation will benefit both graduates seeking jobs, and industrial / social employers who need specific skills in the professional environment. Nanotechnology education has to start at secondary schools, since nano is by now part of the daily environment and schools need to teach about relevant issues to allow informed consumers to take full advantage of nano-enabled products in a safe and sustainable way. NanoEIS will develop novel teaching and assessment tools for secondary schools. In addition, career choices start in school when decisions about study subjects are made, which should be based on full and relevant information, to achieve a good match between the interests of students and the contents of their studies and courses. A website based on the existing NANOfutures site will be set up, as one-stop shop for information on nanotechnology education for all stakeholders, including secondary school students, university students, educators and education administrators, and both industrial (large industry, SME, start-ups) and social employers (regulatory agencies, media, legal and IP services etc.).;571279,2;518176;FP7-NMP-2012-CSA-6;/CSA-SA;PARIS-LODRON-UNIVERSITAT SALZBURG;AT;"AKADEMIA GORNICZO-HUTNICZA IM. STANISLAWA STASZICA W KRAKOWIE;UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN;MALSCH NEELINA HERMINA;NANOFUTURES ASBL;INSTYTUT KATALIZY I FIZYKOCHEMII POWIERZCHNI, POLSKA AKADEMIA NAUK;NANOTECHNOLOGY INDUSTRIES ASSOCIATION;ORT ISRAEL";"PL;IE;NL;BE;IL";/SCI;1;0;0;1;0;0 109849;326551;WOLBACHIA_MOD;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IOF;FP7;The ecology and population dynamics of Wolbachia infections in Aedes aegypti and the development of new strategies for mosquito-borne disease control;2013-10-14;2016-10-13;;An exciting new strategy for biocontrol of mosquito-borne diseases involves the endosymbiotic bacteria Wolbachia that infect several insect species. In the mosquito Aedes aegypti, the major vector of the dengue virus, infection with Wolbachia has been shown to greatly reduce the transmission of human pathogens including the dengue, yellow fever and chikungunya viruses. The Eliminate Dengue project, an international collaboration, is currently developing strategies for releasing Wolbachia into wild A. aegypti populations to render them incapable of transmitting these viruses. The operational success of this strategy relies on the rapid spread of Wolbachia through the mosquito vector population following their initial release. However, the spread of Wolbachia depends on two main factors. Firstly, Wolbachia incur a fitness cost on A. aegypti, which can prevent the bacteria from spreading, particularly if there is a strong fitness cost. In order to design release strategies that will achieve spread, we need to understand the fitness effects of Wolbachia on A. aegypti and how changing environmental conditions influences these effects. Secondly, Wolbachia needs to achieve a threshold prevalence in the mosquito population before it can spread which depends on the fitness cost caused by the bacteria. We need to understand the dynamics of Wolbachia infection in the mosquito population in order to predict release strategies that will allow a sufficiently high prevalence of Wolbachia to be maintained. This fellowship aims to advance our understanding of these ‘individual-level’ and ‘population-level’ processes that determine Wolbachia spread in A. aegypti in order to assist the design of Wolbachia release strategies to successfully drive Wolbachia through wild mosquito populations. An interdisciplinary investigation will develop a new data-driven mathematical modelling approach to predict Wolbachia dynamics under realistic conditions of environmental variability.;376536,2;376536,2;FP7-PEOPLE-2012-IOF;/MC-IOF;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;UK;;;/LIF;1;0;0;1;0;0 109967;335910;VEWA;ONG;FP7-IDEAS-ERC;ERC-SG-PE10;FP7;Ve-Wa:Vegetation effects on water flow and mixing in high-latitude ecosystems–Capability of headwater catchments to mediate potential climate change;2013-10-01;2018-09-30;;'Our ability to predict consequences of climate change on the physical, chemical and biological characteristics of water resources in high-latitude uplands is a formidable challenge. These regions are highly sensitive to climate induced changes as small differences in temperature determine the status of frozen ground, the state of precipitation, and the magnitude and timing of snow accumulation and melt. Recent findings in mid-latitude regions suggest that there exist “two water worlds” – mobile water expressed in the stream and tightly bound water represented by plant water – which means that a substantial proportion of precipitation that infiltrates the soils becomes isolated from discharge to the streams, indicating that the composition of stream water alone is insufficient to understand routing and transit times of water in catchments. These findings challenge the core assumptions in our perceptual models of how we think biophysical systems work and how we make predictions of water partitioning of how inputs of water are evaporated, stored and reach the streams. High-latitude headwater catchments are characterised by lower evapotranspiration, consequent lower soil moisture deficits and different seasonality than mid-latitude sites. This interdisciplinary proposed project will address novel questions on vegetation-water linkages by using isotopic tracers in different waters as 'fingerprints' across different spatial scales along a climate gradient as a precursor to understand future response to change in high-latitude upland catchments. The proposed project will – for the first time - examine the mechanisms of water storage, transmission and release and possible implications of climate change in high-latitude ecosystems along a cross-regional transect. Such geographically extensive comparison has never been conducted in these environments. This allows the consistency of processes and drivers to be assessed across broad spatial scales.';1500000;1500000;ERC-2013-StG;/ERC-SG;THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN;UK;FORSCHUNGSVERBUND BERLIN EV;DE;"/PSE;/ENV;/EAR";1;0;0;1;0;0 105443;316955;OXIOSCR;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-ITN;FP7;Oxford Innovative Organic Synthesis in Cancer Research Doctoral Programme;2013-03-01;2017-05-31;;The Oxford Innovative Organic Synthesis for Cancer Research IDP (OxIOSCR) will seed a revolution in the practice of organic synthesis, by training graduate synthetic chemists for the first time to integrate seamlessly chemical, biocatalytic, and reagentless organic synthesis techniques with the latest advances in reaction technology. The synthetic chemistry will be shaped by a focus on target compounds with mechanism-based substantial anti-cancer activity. This will provide a strong interdisciplinary component to the training programme, by linking with Oxford’s extensive and world-class expertise in fundamental cancer biology and medicinal chemistry. The training programme will lead automatically to more sustainable synthetic routes, new strategies for organic synthesis, a more strongly connected network of chemists and cancer biologists, and will release a generation of fully trained synthesis innovators into the academic and chemical industrial workplace. OxIOSCR is strongly intersectoral, with close involvement of 7 Associated Partners distributed over 6 European countries, crossing academic/industrial, physical/medical science, and public/private sectors.;3816692,22;3816692,22;FP7-PEOPLE-2012-ITN;/MC-ITN;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;UK;;;/LIF;1;0;0;1;0;0 110798;335542;MARKETS;ONG;FP7-IDEAS-ERC;ERC-SG-LS8;FP7;The evolution of plant-fungal markets;2014-02-01;2019-01-31;;"Throughout the Earth’s history, the mutualism between plants and their fungal partners has mediated nutrient cycles and energy flow in ecosystems. Underground, mycorrhizal fungi and plant roots form vast networks of connected individuals, in which sugars from roots are exchanged for nutrients from fungi. How is cooperation maintained in plant-fungal networks? Selfish individuals can potentially exploit the collaboration, reaping nutrient benefits while paying no costs. So, why cooperate at all? I recently demonstrated that plant and fungal partners are able to detect variation in nutrient provisioning by the other, and adjust their own strategy accordingly (Kiers et al. Science 2011). We argued that the partnership functions like an economic market: partners compete by trading resources, and those offering the best rate of exchange are rewarded. While this work suggests that plants and fungi can successfully negotiate conditions of trade, we have yet to conclusively demonstrate what drives ‘fair’ trade dynamics. In particular, we do not know how partner performance is evaluated, nor how trade strategies respond to changes in resource levels. I present an interdisciplinary program of research to address this problem by investigating four aspects critical to market regulation in nature: (1) Responses to external resources, (2) Partner decisions, (3) Network formation, (4) Conflict resolution within networks. Using a combination of gene-level characterization, microscale manipulation of nutrient landscapes, experimental evolution, and game theory, I will test: (1) how plant and fungal trading strategies respond to changing resource levels; (2) how hosts control fungal ‘behavior’, stimulating them to collect specific nutrients; (3) the role of fungal fusion in network formation; (4) how genetic conflicts within a fungal network are resolved. This work opens up a new field of research into how markets evolve and are stabilized in non-animal systems.";1492438;1492438;ERC-2013-StG;/ERC-SG;STICHTING VU;NL;;;"/BIO;/LIF";1;0;0;1;0;0 100597;280271;SRMS4HESUS;ONG;FP7-IDEAS-ERC;ERC-SG-PE4;FP7;Super-resolution mass spectrometry for health and sustainability;2011-11-01;2016-10-31;;"Health and sustainability are the grand-challenges the world faces in the XXI century. The recent progress in science and technology allows now considering these prioritized directions of humanity development at the molecular level. Mass spectrometry is a key analytical technique in receiving the required molecular information from minute amounts of samples present in the gas, solid or liquid phase. The current state-of-the-art in MS applications confirms that investing into basic chemical and physical research is as essential as ever to come prepared for the growing applications challenges and overall for the Europe’s long-term competitiveness and well-being. Within the current proposal, we suggest an interdisciplinary research program to address the challenges in health and sustainability through the scientifical and technological developments in the analytical science. The current project specifically aims at developing the super-resolution mass spectrometry to achieve high resolving power in a short acquisition time period or ultra high resolving power in a long acquisition time period. The former one is crucial for a number of applications in life science and environmental science-oriented proteomics, petroleomics, metabolomics, and imaging. Whereas the latter one would contribute to the long term vision originating from the project’s objectives, specifically molecular isomer differentiation or weighing the chemical bonds in a molecule directly by mass spectrometry. The fundamental insights and knowledge gained during the proposed research can have a deep impact in physical, (bio)chemical and life sciences. The envisioned scientific achievements in the health and sustainability applications may translate into the improved drug discovery, early diagnosis and prognosis for preventive and personalized medicine. The planet and humanity should further benefit from an increase in the sustainability of the energy production and processing.";1425727,68;1425727,68;ERC-2011-StG_20101014;/ERC-SG;SPECTROSWISS SARL;CH;ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE;CH;"/PSE;/MAT";1;0;0;1;0;0 109898;611553;COINVENT;ONG;FP7-ICT;ICT-2013.8.1;FP7;Concept Invention Theory;2013-10-01;2016-09-30;;The capacity of combinational creativity---i.e., when novel ideas are produced through unfamiliar combinations of familiar ideas---is difficult to recreate computationally. In particular, it is a hard task for autonomous computational systems to tackle the combinatorial explosion of potential combinations, and to be capable of recognizing the value of newly created ideas (concepts, theories, solutions, etc.), particularly when they are not specifically sought ---this is the problem of creative serendipitous behaviour.
In this project, we aim to develop a computationally feasible, cognitively-inspired formal model of concept invention, drawing on Fauconnier and Turner's theory of conceptual blending, and grounding it on a sound mathematical theory of concepts. Conceptual blending, although successfully applied to describing combinational creativity in a varied number of fields, has hardly been used for implementing creative computational systems, mainly due to the lack of sufficiently precise mathematical characterizations thereof.
The model to be defined in the context of this project will be based on Goguen's proposal of a Unified Concept Theory, and will draw from interdisciplinary research results from cognitive science, artificial intelligence, formal methods and computational creativity. To validate our model, we will implement a proof of concept of an autonomous computational creative system that will be evaluated by humans in two testbed scenarios: mathematical reasoning and melodic harmonization.
We envisage that the results of this project will be highly significant for gaining a deeper scientific understanding of creativity, for fostering the synergy between understanding and enhancing human creativity, and for developing new technologies for autonomous creative systems.;2715786;2100000;FP7-ICT-2013-10;/CP;AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS;ES;"OTTO-VON-GUERICKE-UNIVERSITAET MAGDEBURG;ARISTOTELIO PANEPISTIMIO THESSALONIKIS;UNIVERSITY OF DUNDEE;GOLDSMITHS' COLLEGE;UNIVERSITAET BREMEN;LIBERA UNIVERSITA DI BOLZANO;UNIVERSITAET OSNABRUECK;THE UNIVERSITY OF EDINBURGH";"DE;EL;UK;IT";/INF;1;0;0;1;0;0 110851;336460;ChromHeritance;ONG;FP7-IDEAS-ERC;ERC-SG-LS3;FP7;Chromosome inheritance from mammalian oocytes to embryos;2014-02-01;2019-01-31;;"One of the most dramatic transitions in biology is the oocyte-to-zygote transition. This refers to the maturation of the female germ cell or oocyte, which undergoes two rounds of meiotic chromosome segregation and, following fertilization, is converted to a mitotically dividing embryo. We aim to establish an innovative research program that addresses fundamental questions about the molecular processes controlling the mammalian oocyte-to-zygote transition to ensure faithful inheritance of genomes from one generation to the next. We are taking an interdisciplinary approach combining germ cell and chromosome biology with cell cycle and epigenetic studies to understand how maternal factors regulate chromosome segregation in oocytes and chromatin organization in the zygote. A molecular understanding of key players regulating these processes is a requisite step for investigating how their deterioration contributes to maternal age-related aneuploidy and infertility. Aneuploidy is the leading cause of mental retardation and spontaneous miscarriage. The current trend towards advanced maternal age has increased the frequency of trisomic fetuses by 71% in the past ten years. A better understanding of mammalian meiosis is therefore relevant to human reproductive health. A special feature of the female germ line is that meiotic DNA replication occurs in the embryo but oocytes remain arrested until the first meiotic division is triggered months (mouse) or decades (human) later. The longevity of oocytes poses a challenge for the cohesin complex that must hold together sister chromatids from DNA synthesis until chromosome segregation. We specifically aim to: 1) elucidate how sister chromatid cohesion is maintained in mammalian oocytes, 2) identify mechanisms regulating cohesion in young and aged oocytes, and 3) investigate how the inheritance of genetic and resetting of epigenetic information is coordinated with cell cycle progression at the oocyte-to-zygote transition.";1499738;1499738;ERC-2013-StG;/ERC-SG;INSTITUT FUER MOLEKULARE BIOTECHNOLOGIE GMBH;AT;;;"/BIO;/LIF";1;0;0;1;0;0 107270;330309;LISCOMF;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IEF;FP7;Light-induced spatiotemporal control of membrane fusion for targeted therapy;2013-10-01;2015-09-30;;"Targeted therapy remains one of the greatest challenges in modern medicine. In response, I propose synthetic, liposomal vectors capable of delivering diverse and clinically relevant therapies to targeted sites in the body, whose therapeutic action is triggered exclusively by applied light. This approach challenges traditional approaches to targeted vector-based therapies and addresses the common failings of existing technologies. The use of light as a stimulus for therapy makes this technology ideally suited to the treatment of skin disorders, including melanoma and non-melanoma skin cancers, dominant negative genetic disorders, infection and inflammation. In execution, the interdisciplinary research program will be a logical and through progression from organic chemistry to cell culture lab and will be underpinned by foreseen pan-European collaboration. The 2-year program will validate the proposed vector as a viable technology for future animal studies and I expect to be in a strong position to apply for follow-up funding following the Fellowship. My 5-year career goal is to establish my own independent research group at one of Europe’s top university backed by long-term and prestigious funding. To achieve this, I must be able to demonstrate: 1) Practical experience across a wide range of disciplines spanning chemistry and biology, 2) Project leadership, 3) People management and mentoring skills, 4) Exposure to and experience of the relationship between academic and commercial sectors, 5) A strong track record of publication and grant applications, 6) Presentation skills, and 7) Demonstrated track record of working effectively in cross-discipline and international collaborations. This proposal has been carefully designed to provide me with all these attributes, putting me in the strongest possible position to achieve my future career ambitions.";175974,6;175974,6;FP7-PEOPLE-2012-IEF;/MC-IEF;UNIVERSITEIT LEIDEN;NL;;;/SCI;1;0;0;1;0;0 96935;265191;INCONTEXT;ONG;FP7-ENVIRONMENT;ENV.2010.4.2.3-1;FP7;InContext: Individuals in Context: Supportive Environments for Sustainable Living;2010-10-15;2013-10-14;;"InContext will investigate drivers and barriers for sustainability and their interplay on an individual and collective level. InContext assumes that both individual and collective behaviours respond to an external context (like social norms, policies, and infrastructure) and an internal context (like needs, values and priorities). So far, initiatives to further sustainable development have focused mainly on external contexts. InContext argues that it is essential to address both sides and include factors like individual needs or subconscious aspects to successfully bridge the gap between awareness and action at individual and collective levels. InContext will: • Study internal and external contexts and the way individuals respond to them to identify drivers and barriers to actions advancing sustainable development. • Conduct participatory scenario development and back-casting exercises in three local communities to generate findings on innovative mechanisms for co-operation and the identification of agents for change. • Improve the understanding of the interplay between internal factors and external factors to behaviour, thereby generating results with regard to the interaction between structural and agent-based factors. • Improve the understanding of how policies at EU and local levels (as part of the external context) can help address the internal context in a way that supports sustainability-driven action. • Identify a set of innovative policy mixes for sustainability-driven action considering the roles of actors on different levels such as policy and opinion makers, business and civil society. InContext attaches great importance to the applicability and distribution of its research results. This concern is reflected in the project design by the integration of a network of local governments and the setting up of an interdisciplinary advisory board allowing for a permanent communication and reality-check by political as well as business professionals.";1840174,6;1496726;FP7-ENV-2010;/CP-FP;ECOLOGIC INSTITUT gemeinnützige GmbH;DE;"HELMHOLTZ-ZENTRUM FUER UMWELTFORSCHUNG GMBH - UFZ;Institute for Agricultural and Forest Environment, Polish Academy of Science;UNIVERSITE LIBRE DE BRUXELLES;ERASMUS UNIVERSITEIT ROTTERDAM;ICLEI EUROPEAN SECRETARIAT GMBH (ICLEI EUROPASEKRETARIAT GMBH)*;SERI - NACHHALTIGKEITSFORSCHUNGS UND -KOMMUNIKATIONS GmbH;DUTCH RESEARCH INSTITUTE FOR TRANSITIONS BV;TECHNISCHE UNIVERSITEIT DELFT";"DE;PL;BE;NL;AT";"/ENV;/SOC";1;0;0;1;0;0 108584;326649;MYOII-DRIVEN FISSION;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IEF;FP7;Reconstitution of Myosin IIA-driven membrane fission in vitro;2014-03-01;2016-02-29;;"Eukaryotic cells contain a variety of membrane-enclosed compartments that are connected by dynamic transport processes facilitated by vesicles. The temporal and spatial regulation of these transport processes is essential for cellular function. After initial formation transport vesicles are separated from their donor membrane and this fission event seems to be coordinated with the elongation of tubular precursors pulled by motor proteins. Recent results from the host laboratory demonstrated a direct interaction of Rab6 (a Golgi-associated RabGTPase) and nonmuscle Myosin II A (MyoIIA) and showed an unexpected function of MyoIIA in the fission of Rab6 transport carriers at the trans-Golgi network. The aim of this project is the development of an in vitro system to mimic the MyoIIA-driven fission process. In this system, we will pull membrane nanotubes from Giant Unilamellar Vesicles (GUVs) using optical tweezers and we will monitor tube stability in the presence of Rab6, MyoIIA, actin and ATP. Two hypotheses will be tested: either MyoIIA induces phase separation in membrane tubes by the formation of actomyosin patches, which then leads to fission; or MyoIIA contracts short actin filaments around the membrane tubes in a manner similar to its role during the formation of the cleavage furrow in cytokinesis. If we do not observe fission in this minimal system, we will add additional factors that have been implicated in fission at the trans-Golgi network. In the past years the cell biology host laboratory of Bruno Goud and the experimental physicists from Patricia Bassereau’s group have collaborated extensively to develop new interdisciplinary methods to investigate intracellular transport processes. As I have so far focused on biophysical measurements with Rab proteins in the absence of membranes, the development of the in vitro system in these laboratories will give me the possibility to get exposure to a variety of new techniques that will expand my current expertise.";194046,6;194046,6;FP7-PEOPLE-2012-IEF;/MC-IEF;INSTITUT CURIE;FR;;;/SCI;1;0;0;1;0;0 101132;289454;NANODRUG;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-ITN;FP7;Novel nanoparticles for drug delivery to the skin;2011-11-01;2015-10-31;http://www.nanodrug.qmul.ac.uk/;The aim of the NANODRUG Network is to contribute to the defragmentation of the emerging field of nanomedicine by providing a unique training programme that will cover all different aspects ranging from NP synthesis and characterisation, drug delivery, molecular biology to nanotoxicology, preclinical studies, risk assessment and nanotechnology policy making. The NANODRUG training program is far superior to any training that individual partners can provide and will equip researchers with innovative and creative skills and enhance their career prospects in the public and private sectors. The scientific aim of this research training network is to develop and characterise a selected set of novel intelligent nanomaterials and to study their suitability as novel drug delivery systems targeting inflammatory skin diseases. The development and use of the NP described in this project aims to overcome the current difficulties that limit the applications of NP to skin drug delivery. The unique physico-chemical properties of these novel NP such as ultra small size, large surface to mass ratio, high reactivity and the capability to tailor them to applications will ensure that when complexed with drugs the pharmacokinetics and therapeutic index of the delivery systems can be significantly improved compared to the free molecules and the capability to pass the SC of the skin greatly enhanced. This project brings together 6 academic groups and 2 industrial teams as full partners, complemented by 3 associate partners, one of which is an industrial team, distributed over a total of 6 EU member states and 1 non-ICPC country. The consortium brings together groups with a very interdisciplinary expertise ranging from polymer synthesis and characterisation, computational modelling and physicochemical characterisation of materials to bioavailability, NP formulation, drug distribution and nanotoxicity, genetics, drug delivery and clinical dermatology.;3752752,62;3752752,62;FP7-PEOPLE-2011-ITN;/MC-ITN;QUEEN MARY UNIVERSITY OF LONDON;UK;"UNIVERSITE CATHOLIQUE DE LOUVAIN;CENTRO DE NEUROCIENCIAS E BIOLOGIACELULAR ASSOCIACAO;SANOFI-AVENTIS RECHERCHE & DEVELOPPEMENT;MJR PHARMJET GMBH;UNIVERSITAET INNSBRUCK;CRANFIELD UNIVERSITY;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS";"BE;PT;FR;DE;AT;UK";"/LIF;/SCI";1;0;0;1;0;0 101120;286409;QUANTATEC;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IAPP;FP7;Novel Short Wavelength Quantum Cascade Lasers for HIgh Sensitivity Gas Detection;2011-11-01;2015-10-31;;"The overall aim of the work described in this proposal is to create a long-term strategic partnership between Sheffield University, Radboud University, M-Squared Lasers and Sensor Sense in order to develop a new generation of instrumentation for ultra-high sensitivity trace gas detection based on novel, mid infrared quantum cascade lasers emitting in the 3-4 micron wavelength range. The 3-4 micron wavelength range is of key technological importance for a wide range of applications. Many important hydrocarbon species, for example ethane, methane, acetone, formaldehyde and butane and other molecules such as hydrogen halides have their strongest absorption features in this region, and detection sensitivities are therefore maximised. This leads to many potential applications in areas such as clinical diagnostics (breath analysis), process monitoring, control of outdoor and indoor pollution, remote detection of oil and gas deposits and explosives and concealed weapons detection. Consequently, there is very strong motivation for the development of compact, high performance sensing systems in this wavelength range, which will provide major opportunities for wealth creation and enhanced quality of life. This highly interdisciplinary project brings together leading groups with strongly complementary and synergistic expertise in semiconductor physics, infrared lasers, optoelectronics technology, molecular absorption spectroscopy and advanced gas detection technologies. The consortium is thus very strongly placed to make major contributions to EU competitiveness in this increasingly important technological area.";1021370;1021370;FP7-PEOPLE-2011-IAPP;/MC-IAPP;THE UNIVERSITY OF SHEFFIELD;UK;"STICHTING KATHOLIEKE UNIVERSITEIT;M-SQUARED LASERS LIMITED;Sensor Sense B.V.";"NL;UK";/IND;1;0;0;1;0;0 103616;298900;EUTRANSGOV;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IEF;FP7;Transferring Good Governance in the EU´s Neighbourhood;2012-09-01;2015-03-03;;"'EUTRANSGOV concentrates on the transfer of good governance / institution-building (‘soft’ norms) in the EU’s neighbourhood, a topic which has attracted further attention since the revolutions in North Africa. Policy transfer gained momentum in International Relations and EU Studies to highlight changes within and outside the EU. This project complements research on EU enlargement and the European Neighbourhood Policy (ENP) in establishing an interdisciplinary cartography of the various approaches in “Policy Transfer Studies”. Its analytical framework, combined with an original methodology, allows for the identification of unexplored empirical case studies and transferable knowledge on successful (or less successful) norm and policy transfers in EU external relations. Three objectives need to be fulfilled to accomplish the project: Objective 1: to clarify the concepts of policy transfer and related notions in EU external relations. Objective 2: to elaborate an analytical framework with a pluralist methodology. Objective 3: to enhance empirical knowledge on the transfer of good governance in the EU’s neighbourhood. As results, the applicant expects: - to contribute greatly to academic debates in clarifying the use of policy transfer and good governance in EU external relations; - to advance the knowledge on the concrete ('real world') functioning of EU foreign policy and on its impact in the EU’s direct neighbourhood and abroad; - to enhance the visibility of the applicant’s past and current research activities for the applicant’s own career advancement.'";269096,4;269096,4;FP7-PEOPLE-2011-IEF;/MC-IEF;FONDATION NATIONALE DES SCIENCES POLITIQUES;FR;;;/SCI;1;0;0;1;0;0 99503;277000;ANTIBACTBIODENTCOMP;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-RG;FP7;Development of novel bactericidal dental bioactive composites for prosthetic restorations;2011-07-01;2014-06-30;;"Secondary caries and cement dissolution represent two of the most common reasons of fixed prosthetic restorations failure which are caused by the marginal gap that exists between tooth and restoration, which is open to oral bacteria. The significant research objective of the present research is the prolongation of the lifetime of fixed ceramic restorations, which should be achieved by eliminating secondary caries, avoiding micropenetration of oral bacteria and by supporting healthy periodontal regeneration. To achieve this objective, the proposed research project will develop and introduce in dental clinical practice a new family of composite bioactive materials with antibacterial properties. The planed research work consists of three main tasks: a) development of two different processing protocols (incorporation of silver particles, sol-gel preparation method) for fabricating new bioactive Ag-doped silicate composite materials, b) complete characterization of microstructural properties, antibacterial effects and biological behavior of the newly developed products and c) establishment of the optimum implementation approach for the new dental composites in a clinical setting. With successful completion of the project, new dental materials will be available which are capable of creating a bacterial free environment with the marginal area being kept sealed through the healthy periodontal attachment to the biomaterial, intentionally placed in contact to periodontal ligament. The implementation of the project provides an innovative and interdisciplinary scientific and technological concept. The project results are expected to complement related themes of the FP7 research agenda, with particular impact on the fields; dental health, materials science, microbiology and cell biology. An additional impact will be the professional integration of the applicant to a European university, strengthening quantitatively and qualitatively the human potential in research in Europe.";45000;45000;FP7-PEOPLE-2010-RG;/MC-ERG;ARISTOTELIO PANEPISTIMIO THESSALONIKIS;EL;;;/SCI;1;0;0;1;0;0 99192;284558;GRAPHENE-CA;CLO;FP7-ICT;ICT-2011.9.5;FP7;Coordination Action for Graphene-Driven Revolutions in ICT and Beyond;2011-05-01;2012-04-30;;This Coordination Action aims to prepare a European Flagship project focussed on 'Graphene-Driven Revolutions in ICT and Beyond' (GRAPHENE). The overwhelming current focus on graphene, discovered by A.K. Geim and K. Novoselov in 2004, is driven by the considerable and tantalizing potential that this material offers in conventional as well as radically new fields of ICT applications.
Europe can play a key role in future graphene-based ICTs provided a long term strategy of transferring knowledge and intellectual property to technological applications is carried out in a coordinated, effective and organized fashion. GRAPHENE-CA will establish a comprehensive scientific and technological roadmap, by taking advantage of the activities of an existing nanoICT graphene working group, contributions of selected industrial partners and key scientists such as the Nobel Laureates A.K. Geim, K. Novoselov, A. Fert and K. von Klitzing. This roadmap will be the basis to develop the research agenda for the subsequent GRAPHENE flagship, which will cover electronics, spintronics, photonics, plasmonics and mechanics based on graphene, and supporting areas such as graphene production and graphene chemistry.
The CA will frame the development of a graphene flagship that is aimed to serve as a sustainable incubator of new branches of ICTs applications, rooted on European scientific excellence and interdisciplinarity (merging physics and chemistry with engineering communities), and providing Europe a strategic instrument and infrastructure for innovation in ICT-related science and applications.;1581333;1355000;FP7-ICT-2011-FET-F;/CSA;CHALMERS TEKNISKA HOEGSKOLA AB;SE;"THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;THE UNIVERSITY OF MANCHESTER;NOKIA OYJ;FUNDACIO INSTITUT CATALA DE NANOCIENCIA I NANOTECNOLOGIA;FONDATION EUROPEENNE DE LA SCIENCE;GESELLSCHAFT FUR ANGEWANDTE MIKRO UND OPTOELEKTRONIK MIT BESCHRANKTERHAFTUNG AMO GMBH;CONSIGLIO NAZIONALE DELLE RICERCHE;LANCASTER UNIVERSITY";"UK;FI;ES;FR;DE;IT";/ITT;1;0;0;1;0;0 102932;303559;IMANILBCAT;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-CIG;FP7;Interferometric Microscopy and Nanoscopy in Live Biological Cells and Tissues;2012-04-01;2016-03-31;;"The current research proposes new optical spectroscopic and interferometric microscopy and nanoscopy techniques for accurate measurements and visualization of biological cell structure, organization, stiffness and dynamics by recording the cell spatial, temporal, and refractive-index structure on sub-wavelength and sub-Hertz scales. The following objectives are proposed: (a) Novel optical-mechanical signatures of cancer cells measured by wide-field digital interferometry: I propose to establish multi-disciplinary cancer biomarker using the stiffness signatures of cancer cells measured in a noncontact, quantitative and label-free manner by wide-field digital interferometry (WFDI). (b) Interferometric and spectroscopic diagnosis of red blood cell diseases: I propose to measure mechanical and morphological properties of live red blood cells (RBCs) with extremely high sensitivity in a non-destructive, noncontact and label-free manner, as a mean to learn about the biomechanical properties of the RBC membrane and as a novel diagnosis tool for diseases that change morphology and mechanical properties of RBCs. (c) Developing plasmonic-nanoparticle-based interferometric methods for Alzheimer's disease research: I propose to develop new nano-sensing and imaging modalities as a means to monitor degradation of neuronal function due to Alzheimer's disease. I will use photothermal optical coherence tomography with nanoparticles bound to amyloid beta to detect the degeneration in neuronal activity. This system will be combined with a low-coherence WFDI system for quantitative phase imaging of rapid dynamic neuronal phenomena. The proposed objectives are highly interdisciplinary, involving optical engineering, sensing in biological systems, biophysics, nanoscience, neurobiology, and disease research, and have a great potential of providing new means for diagnosis and monitoring of diseases in the sub-cellular level, as well as aiding in identifying new avenues for therapy.";100000;100000;FP7-PEOPLE-2011-CIG;/MC-CIG;TEL AVIV UNIVERSITY;IL;;;/SCI;1;0;0;1;0;0 101717;290056;MMMPA;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-ITN;FP7;Training Network for Monitoring Mediterranean Marine Protected Areas;2012-01-01;2015-12-31;http://www.mmmpa.eu/;"The Initial Training Network for Monitoring Mediterranean Marine Protected Areas (MMMPA) aims to train the next generation of MPA scientists and managers, equipping them with a flexible set of skills essential within a wide range of professional environments, including public administration, local authorities, industry and academia. They will focus on the most important aspects that need adequate conservation. In particular, researchers will maturate the experience to: identify species listed in the Barcelona Convention (Protocol ASPIM, Annex II); monitor their distribution and health state; follow adequate experimental designs; evidence spill-over effects; develop fishery management at the local level, develop management guidelines, engage with stakeholders and the society at large. These experiences will stem from a highly interdisciplinary network, leading in taxonomy, ecology, biology conservation, bio-cartography, and socio-economy. Furthermore, they will be trained in a range of soft skills including science communication/outreach, as it is essential at the delicate interface between science, the management of natural assets and the public at large. Training and hands-on experiences will be delivered by a strong network of world-class experts in MPA management which will provide a highly focused learning environment. The consortium includes 7 Full (5 Universities, 1 Research centre, 1 SME) and 6 Associated partners (4MPAs, 2 SMEs), and will recruit 10 ESRs (360pm) and 4 ERs (24pm). Both Full and Associated partners have strong collaborative links with other (MPAs) scientists, professionals and managers and are, therefore, well placed to deliver a comprehensive training network. The planned rotation will expose ESR/ERs to each partner, enhancing intersectoral exchanges and strengthening the Mediterranean Research Area by developing an exciting programme that is attractive to the global research community.";2914070,44;2914070,44;FP7-PEOPLE-2011-ITN;/MC-ITN;UNIVERSITA POLITECNICA DELLE MARCHE;IT;"ETHNIKO KAI KAPODISTRIAKO PANEPISTIMIO ATHINON;HELLENIC CENTRE FOR MARINE RESEARCH;UNIVERSITE DE NICE SOPHIA ANTIPOLIS;UNIVERSIDAD DE MURCIA;ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA;UBICA SRL";"EL;FR;ES;IT";"/LIF;/SCI";1;0;0;1;0;0 103543;295362;BILITERACY;ONG;FP7-IDEAS-ERC;ERC-AG-SH4;FP7;Bi-literacy: Learning to read in L1 and in L2;2012-05-01;2017-04-30;;"Learning to read is probably one of the most exciting discoveries in our life. Using a longitudinal approach, the research proposed examines how the human brain responds to two major challenges: (a) the instantiation a complex cognitive function for which there is no genetic blueprint (learning to read in a first language, L1), and (b) the accommodation to new statistical regularities when learning to read in a second language (L2). The aim of the present research project is to identify the neural substrates of the reading process and its constituent cognitive components, with specific attention to individual differences and reading disabilities; as well as to investigate the relationship between specific cognitive functions and the changes in neural activity that take place in the course of learning to read in L1 and in L2. The project will employ a longitudinal design. We will recruit children before they learn to read in L1 and in L2 and track reading development with both cognitive and neuroimaging measures over 24 months. The findings from this project will provide a deeper understanding of (a) how general neurocognitive factors and language specific factors underlie individual differences – and reading disabilities– in reading acquisition in L1 and in L2; (b) how the neuro-cognitive circuitry changes and brain mechanisms synchronize while instantiating reading in L1 and in L2; (c) what the limitations and the extent of brain plasticity are in young readers. An interdisciplinary and multi-methodological approach is one of the keys to success of the present project, along with strong theory-driven investigation. By combining both we will generate breakthroughs to advance our understanding of how literacy in L1 and in L2 is acquired and mastered. The research proposed will also lay the foundations for more applied investigations of best practice in teaching reading in first and subsequent languages, and devising intervention methods for reading disabilities.";2487000;2487000;ERC-2011-ADG_20110406;/ERC-AG;BCBL BASQUE CENTER ON COGNITION BRAIN AND LANGUAGE;ES;;;/MED;1;0;0;1;0;0 103855;300596;COCONPRESS;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IOF;FP7;'Re-presenting the 'Black Legend': conflict, coalition and the press in early modern Europe';2012-09-14;2016-03-22;;"This innovative project, to be carried out at Harvard University plus other significant Portuguese collections in Europe, explores the oldest diplomatic alliance in Europe (the ‘Treaty of Windsor’, 1386), which is technically still in force. It explores issues of religious conflict, xenophobia and political propaganda that remain issues in contemporary Europe, providing a historical perspective on European cultural and political integration. Access to American archives and research expertise will bring new methods and materials to this neglected, but significant, alliance. The main output will be a monograph, and an international, interdisciplinary conference in Portugal will develop research networks to publicise research findings to the European academic community. Ratified as an ‘Anglo-Portuguese Alliance’, this pact formed, above all, an alliance against Spain. During the period c.1480-1680 both countries were seafaring empires on the rise, and both saw themselves as having much to fear: from Moorish invasion, from the Jews, but, most especially, from the threat of Spanish domination. The project argues that the rise of the ‘Black Legend’, the systematic demonizing of Spain via the press, was in fact an Anglo-Portuguese alliance. The fear of ‘the other’, of other races and creeds, increased as propaganda about neighbouring countries spread like a virus across the European press. The project will uncover the sources and personnel behind much of this printed literature. It will also uncover the espionage that raged behind the political machines. Newly discovered documents and printed sources in America prove how a Protestant and a Catholic regime united for a common cause: to prevent domination by another country. This will be the first major study to scrutinise their joint actions at home, rather than in the colonies. These complex political manoeuvrings have, for too long, sat in the wings of historical inquiry: this project places them centre stage.";271943,7;271943,7;FP7-PEOPLE-2011-IOF;/MC-IOF;BRUNEL UNIVERSITY LONDON;UK;;;/SCI;1;0;0;1;0;0 103831;302804;MicroEncapsDelivery;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IEF;FP7;MicroEncapsDelivery;2012-09-01;2014-08-31;;In this multidisciplinary research proposal we aim to develop a new therapeutic platform for hepatocellular carcinoma (HCC). HCC is the third leading cause of cancer death worldwide with a death rate greater than 600,000 persons annually. Currently the main curative treatments include resection, liver transplantation, or percutaneous local ablative treatment. However, all these approaches are primarily suitable for asymptomatic patients with very early and early HCCs. Transarterial chemoembolization (TACE) is the primarily indicated treatment for HCC. New evidence suggests that TACE with doxorubicin-eluting beads is superior to conventional TACE, in terms of reduced adverse event rates and improved survival. These beads are impregnated with doxorubicin, which is slowly released after being infused into the tumour vessels allowing a delivery of high intratumoral concentrations with a low serum doxorubicin level. Ideally, the injected chemotherapeutic should be retained in the tumor and be gradually released to avoid systemic toxicity. However, its selective injection is associated to significant passage into the systemic circulation. To improve drug delivery to the liver, the project “MicroEncapsDelivery” aims to develop a new therapeutic platform for the treatment of HCC that will deliver locally at the tumour the angiogenesis inhibitor hemopexin-like protein (PEX) and the immunostimulatory cytokine interleukin 12 (IL-12). This interdisciplinary therapeutic approach encompasses microencapsulation of genetically modified bone marrow derived mesenchymal stem cells, within biocompatible alginate beads, for the continuous and localised delivery of the therapeutic factors. Our goal is to develop the cell microcapsules and optimise and characterise the pharmacological profiles of PEX and IL-12 in vitro and their biodistribution in vivo in an established HCC rabbit animal model. The result will be dramatically reduced tumour in a manner that was unachievable until now.;161065,2;161065,2;FP7-PEOPLE-2011-IEF;/MC-IEF;IDRYMA IATROVIOLOGIKON EREUNON AKADEMIAS ATHINON;EL;;;/SCI;1;0;0;1;0;0 99147;267351;NEUROCMOS;ONG;FP7-IDEAS-ERC;ERC-AG-PE7;FP7;Seamless Integration of Neurons with CMOS Microelectronics;2011-06-01;2016-05-31;;"We propose to seamlessly integrate advanced microelectronics and living neuronal cells in a comprehensive and interdisciplinary approach to significantly advance the understanding of neuronal behaviour. The project includes (a) the development of a novel multifunctional microelectronics chip platform in complementary metal oxide semiconductor (CMOS) technology, which serves to enable (b) key neurobiological and neuromedical research on network dynamics and plasticity of rodent neuronal networks and visual encoding in retinae, and (c) the necessary concurrent development of algorithms and models to efficiently process and maximally harness the unprecedented quality of the obtained data. Neuronal or retinal preparations, such as acute and organotypic brain slices (retinae) or primary cultured, dissociated cells, will be directly placed or grown atop dedicated CMOS microelectronics chips. The chips will feature multiple functions, since neurons carry and pass signals to each other using electro-chemical mechanisms: electrophysiological recording & stimulation, in closed loop & real time, as well as highly spatially resolved impedance measurements and detection of neuroactive chemical compounds. The chips will be capable of delivering any of these functions to arbitrarily selectable individual cells or even subcellular units, and, at the same time, of interacting with a multitude of cells or complete neuronal networks. Along with imaging (light, fluorescence), pharmacological, and/or genetic methods, the developed chip platform will be used to study neuronal network dynamics, synaptic and axonal plasticity, relevant for many brain diseases, as well as visual encoding in the retina. Efficient data handling and spike sorting algorithms will be developed to facilitate these investigations. The multidimensional data will then be used to establish detailed models of neurons and neuronal networks.";2498000;2498000;ERC-2010-AdG_20100224;/ERC-AG;EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH;CH;;;"/PSE;/ICT;/TEL;/NET";1;0;0;1;0;0 85434;216025;BIND;CLO;FP7-ICT;ICT-2007.3.2;FP7;Biaxial Nematic Devices;2008-02-07;2012-02-06;http://bind.upatras.gr/;The recent experimental discovery of novel biaxial liquid crystal (LC) phases is a major breakthrough in functional materials and presents a challenge to develop the technology for a new generation of faster biaxial LC displays. These expectations are based on the existence of a secondary director that can be controlled by external fields. However, to be put in practice, this new possibility requires rethinking LC displays and materials as we know them now.
BIND, a collaborative research project on biaxial nematic electro-optic device systems and materials, aims to provide the basic know-how enabling the production of a new generation of fast LC displays. It comprises (i) deepening the fundamental understanding of structure-properties relationships in biaxial nematic materials, with a particular view to bring their range of stability down to room temperature, (ii) developing experimental protocols for the identification and quantification of biaxiality and (iii) investigating novel alignment methods and candidate display architectures. The technological objective is to demonstrate the first working device based on nematic biaxiality.
To go from basic understanding of materials properties to working devices, an interdisciplinary consortium of leading research teams has been assembled. Expertise in BIND encompasses state-of-the-art chemical synthesis and characterisation, physical measurement, molecular modelling, computer simulation and design of liquid crystal devices. A variety of liquid crystal types will be assessed, ranging from low-molar-mass nematics to oligomers, multipodes, linear polymers and elastomers.
Solving a scientific problem by leading European research groups, and taking this through from fundamental studies to applications, presents a unique opportunity for the EU to take a leading role in developing the know-how on biaxial displays and thereby to strengthen its position in a research area that is presently at the edge of emerging technologies.;3166915;2399999;FP7-ICT-2007-1;/CP;PANEPISTIMIO PATRON;EL;"MARTIN-LUTHER-UNIVERSITAET HALLE-WITTENBERG;THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN;ALBERT-LUDWIGS-UNIVERSITAET FREIBURG;UNIVERSITY OF HULL;ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD";"DE;IE;UK;IT";"/ELM;/ICT;/IPS;/TEL";1;0;0;1;0;0 102409;280020;ORANOS;ONG;FP7-IDEAS-ERC;ERC-SG-PE3;FP7;Organic Nanospintronics;2012-03-01;2017-02-28;;"Research on organic spintronics, which is especially promising due to the prospects of exceptionally long spin lifetimes in organic semiconductors, is currently in a critical phase. After a very successful starting period, progress is now being hampered, largely due to a limited understanding of the critical interfacial properties involved. The mechanisms behind the observed spin valve effects remain poorly understood, and unambiguous evidence of spin polarized transport (other than tunnelling) in organic semiconductors is still lacking. The properties of the hybrid inorganic/organic interfaces are of paramount importance for the device behaviour, and are key to solving the puzzle associated with the physics behind the observed magnetoresistance effects. So far a direct link between device characteristics and interfacial properties remains elusive. In this proposal, we pursue a reliable way to address these crucial issues and to guarantee the progress needed to take the field to the next level. As a first main objective, we will combine interface preparation and characterization with in-situ device fabrication and testing, using a single dedicated UHV setup equipped with all necessary tools, i.e. spin (and angle) resolved photoelectron spectroscopy, LEED and STM, and magnetotransport, to establish a direct link between interfacial properties and device characteristics. The second main objective is to develop new device architectures, optimized for electrical probing of spin polarization in organic semiconductors. These joined efforts form a highly challenging task, since they require a strongly interdisciplinary approach, combining different complementary expertises. The PI is in a truly unique position to carry out this timely project successfully, having a strong and well documented background in 1) electron spectroscopic characterization techniques of electronic and magnetic properties of hybrid interfaces and 2) spintronic devices and spin polarized transport.";1494640;1494640;ERC-2011-StG_20101014;/ERC-SG;UNIVERSITEIT TWENTE;NL;;;"/PSE;/ELM;/NNT";1;0;0;1;0;0 95731;256571;ELIOT;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-RG;FP7;Electronic and Ionic Transport in Functional Oxides;2010-10-01;2014-09-30;;Two of the main drivers of worldwide economic growth and scientific development are the semiconductor/IC industry and the need for new energy resources. The need for alternate renewable sources of energy such as sunlight and wind power which are inherently discontinuous, poses new challenges for energy transport and storage. Although many of the materials used in the IC industry and in energy storage are similar, the research in their properties has been separated in two fields with very little interdisciplinary interaction. This proposal aims to cross this barrier and evaluate physical and electrical properties of transition metal oxides in their nanostructured form for non-volatile memory and energy storage applications. For this we will investigate how material production and physical properties influence electronic and ionic transport properties in these oxides. We propose to evaluate transition metal oxides, starting with simple binary oxides such as vanadium oxides and assess how material production and physical properties influence electrical and/or ionic transport properties. A first objective is to identify materials where resistive switching can be ascribed to correlated electron effects rather than oxygen or oxygen vacancy rearrangement. It is interesting to determine how these effects are influenced by size and confinement. This is done keeping in mind possible applications as switch/ memory elements. Some oxides are expected to show relatively high ionic mobility making them good candidates for alternate battery materials. For this, screening of ionic mobility of the intrinsic oxide and of Li in the oxide is to be investigated. Correlating oxygen mobility in the lattice with Li mobility can help better engineer materials for highly performing batteries.;100000;100000;FP7-PEOPLE-2009-RG;/MC-IRG;INTERUNIVERSITAIR MICRO-ELECTRONICA CENTRUM;BE;;;/SCI;1;0;0;1;0;0 100823;286145;MICRO-THERAPY;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IAPP;FP7;Eco Friendly Tuneable Microwave continuous Flow Reactor for the Synthesis of Lecucettamines in Therapeutic Activity Against Alzheimer's Disease;2011-10-01;2015-09-30;;"The four-year MICRO-THERAPY is a fully integrated interdisciplinary proposal which will develop a new area of competence in the three partners, Liverpool John Moores University, University of Rennes1 and ManRos Therapeutics. It brings together a powerful set of partners covering fully the three key aspects - microwave engineering, chemistry and biology to create new technology and sustainable technical and scientific expertise applicable to the bio-pharmaceutical industry. The proposed research programme is unique in terms of generating a tuneable, multipurpose, microwave, continuous, atmospheric pressure, flow reactor for the efficient conduct of various chemical reactions for the synthesis of Leucettamines to be used against Alzheimer’s disease. Unlike the restricted batch reactors a continuous microwave reactor has the potential to operate at high production rates simply by virtue of offering continuous throughput and, more significantly, by being easy to replicate allowing scale up the process for bulk production at commercial rates. In addition the system will operate for the first time with tuneable frequency microwaves in the range 2.45 – 8GHz in order to optimise the process to produce higher yields with reduced separation costs. This is unlike current microwave synthesis where the source is only operated at one fixed frequency of 2.45GHz and is therefore not necessary have the optimum operating frequency to suit various chemicals reactions at different temperatures. The timeliness of MICRO-THERAPY is a response to demand for new ways to produce chemicals for the therapeutic activities against Alzheimer’s disease. However, such a reactor also has scope fore much wider application The main objectives of this project are to: 1. To use the project to develop new cross-disciplinary expertise through the recruitment of experienced researchers to work particularly at LJMU and UR1, but also incorporating expertise at MRT thereby providing new training and development opportunities for young and experienced researchers at the partners, blending an expanding knowledge base and unique skills to produce key proficiencies. 2. To specifically develop a multipurpose prototype reactor for the synthesis of bulk quantities of chemicals on a continuous basis by using novel atmospheric pressure, continuous microwave flow reactor. 3. To select the reaction time, flow rate, microwave power and frequency within the operating range 2.45 to 8GHz to produce chemicals with high yield, low waste and using low power in comparison with the conventional techniques.";653242;653242;FP7-PEOPLE-2011-IAPP;/MC-IAPP;LIVERPOOL JOHN MOORES UNIVERSITY;UK;"ManRos Therapeutics;UNIVERSITE DE RENNES I";FR;/IND;1;0;0;1;0;0 103135;303091;ODOR CONTEXT;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IIF;FP7;Neural mechanisms underlying the encoding of sensory and contextual information in primary olfactory cortex;2012-03-01;2014-02-28;;"I am interested in understanding how sensory percepts lead to behavior. Olfaction is one of the most dominant senses across many organisms. For rodents, the sense of smell is particularly crucial. The context in which odors are experienced is a not only a critical component in decoding the behavioral significance of the odors but also powerfully influences their perceptual qualities. The neural mechanism underlying the integration of contextual information and odor identity is unknown. This proposal aims to understand how the spatial context of an olfactory object is encoded in the olfactory cortex of mice. Taking an interdisciplinary approach, I will use a novel spatial context-dependent olfactory discrimination task, in combination with in vivo recordings and optogenetic manipulation to study the representation of odor and contextual information in populations of olfactory cortical neurons during behavior. I will also perform anatomical analysis and patch-clamp recordings from brain slices to understand the neural circuit mechanisms that underlie my findings in vivo. I will be hosted by the group of Dr. Zachary Mainen in the newly established Champalimaud Neuroscience Program in Portugal. The systems neuroscience focus of the CNP, my past research experience, scientific interest, and future career goals makes this proposal the perfect match for both the host and I. This project will not only provide data on fundamental and unanswered questions in sensory neuroscience, it will also allow me to develop a multidisciplinary approach to systems neuroscience. By combining sophisticated behavioral assays with cutting-edge techniques in optogenetics and neurophysiology, this project will put the host lab and I at the forefront of systems neuroscience research, and strengthen my potential for becoming a principal investigator. By funding this study, the Marie Curie Work Programme will secure its long-held leading role in supporting innovative neuroscience research.";151426,8;151426,8;FP7-PEOPLE-2011-IIF;/MC-IIF;FUNDACAO D. ANNA SOMMER CHAMPALIMAUD E DR. CARLOS MONTEZ CHAMPALIMAUD;PT;;;/SCI;1;0;0;1;0;0 109496;607062;ESSENCE;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-ITN;FP7;Evolution of Shared Semantics in Computational Environments;2013-11-01;2017-10-31;;"'In everyday life, humans exhibit strong skills in resolving communication problems by re-negotiating what they mean. Modern-day computational systems, however, are lacking in resilience and robustness in this respect. Whenever different components with different vocabularies and models of meaning interact within distributed, open enviroments, they have to rely on their human designers’ abilities to resolve problems of miscommunication. The aim of the ESSENCE network is to translate these abilities of natural communicating systems to computational systems in order to improve their resilience and robustness, and by doing so to also make these systems more comprehensible to human users. To this end, we will bring together research on phenomena observed in human communication with research from areas that investigate heterogeneous computational communicating systems. We will develop a transnational virtual research centre that brings together researchers from computational systems that take inspiration from human-based models and vice versa. Within this centre, we will generate new expertise through research on specific sub-topics, which will act as thematic focal points within the area of shared, evolving semantics. This will be achieved by training a new cadre of researchers in the state of the art of both fields, adopting a holistic approach that spans across existing disciplinary boundaries. Our programme of interdisciplinary and cross-sectorial training will involve a diverse range of non-academic and industrial partners, and will ground our research in appropriate application contexts to improve the employability of network participants. ESSENCE will build a sustainable European research base for future training, research collaboration and commercial exploitation of new techniques in the area. It will establish strong collaborative links with third parties, and promote interest in the broader area through targeted public engagement and outreach activities.'";3990183,57;3990183,57;FP7-PEOPLE-2013-ITN;/MC-ITN;THE UNIVERSITY OF EDINBURGH;UK;"TAIGER SPAIN SL;VRIJE UNIVERSITEIT BRUSSEL;AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS;SONY EUROPE LIMITED;UNIVERSITA DEGLI STUDI DI TRENTO;UNIVERSITEIT VAN AMSTERDAM";"ES;BE;UK;IT;NL";/LIF;1;0;0;1;0;0 96854;264600;INFLAME;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-ITN;FP7;Indoor Contamination with Flame Retardant Chemicals: Causes and Impacts;2011-01-01;2014-12-31;;"The main research goal is to further understanding of how and to what extent flame retardant (FR) chemicals used in every-day consumer goods and construction materials enter humans and of the risk to health that such exposure presents. Our vision is that this enhanced understanding will inform assessment of risk associated both with recent and current-use flame retardant chemicals, and of those under development, and ultimately lead to more sustainable approaches to meeting fire safety regulations. Our principal objectives are to discover: (1) the mechanisms via which FRs migrate from products within which they are incorporated; (2) how and to what extent such migration leads to human exposure; and (3) the effects of such exposure. To achieve our goal and objectives we will use a range of state-of-the-art techniques associated with analytical chemistry, electron microscopy, mathematical modelling, in vitro toxicology, and “omics”. The network is an interdisciplinary cooperative of chemists, biologists, physicists and toxicologists. Intersectoral aspects unite basic and applied scientists working in universities, two SMEs, a large (non-university) public sector research organisation and a government research institute. The project’s S&T objectives will be delivered through research in 3 Work Packages (WPs): viz. WP1- Migration pathways, WP2- Human exposure (pathways and monitoring), and WP3- Understanding effects of human exposure. The aim of the Training Programme is to increase the knowledge base and experience of trainees in the different research areas and to develop their transferable skills for future careers in the private sector, public sector, or the regulatory community. Six training objectives will be delivered through a suite of 6 Core Skills Areas (Research Project, Advanced Training Courses, Project Meetings, Career Development Plan, Generic Research Skills, Transferable Research Skills).";3631363;3631363;FP7-PEOPLE-2010-ITN;/MC-ITN;THE UNIVERSITY OF BIRMINGHAM;UK;"FOLKEHELSEINSTITUTTET;VLAAMSE INSTELLING VOOR TECHNOLOGISCH ONDERZOEK N.V.;UNIVERSITEIT ANTWERPEN;IVL SVENSKA MILJOEINSTITUTET AB;STICHTING VU;THE UNIVERSITY OF READING;VERENIGING VOOR CHRISTELIJK HOGER ONDERWIJS WETENSCHAPPELIJK ONDERZOEK EN PATIENTENZORG;Academisch Medisch Centrum bij de Universiteit van Amsterdam;STOCKHOLMS UNIVERSITET";"NO;BE;SE;NL;UK";"/EDU;/NET";1;0;0;1;0;0 192377;339778;RNAQUAD;ONG;FP7-IDEAS-ERC;ERC-AG-LS1;FP7;The chemical biology of RNA G-quadruplexes;2014-04-01;2019-03-31;;'For over a decade, our research programme has focused on the chemical biology of nucleic acids. The structure of nucleic acids is key to their biological functions, and the four-stranded guanine rich class of structures called G-quadruplexes constitute a particularly intriguing motif. Recent evidence suggests a role for G-quadruplex (G4) structures in RNA leaving their fundamental importance in biology open for exploration. Our central hypothesis is that the G4 structural motif, rather than its sequence per se, conveys important function(s) in RNA. We propose to directly address this hypothesis by the experimental identification of functional RNA G4 structures within the cellular transcriptome on a genome-wide scale. In particular, we intend to reveal detailed insights into their functional contributions to: a) translation and b) telomere biology. The proposed programme constitutes an integrated, interdisciplinary approach that combines chemical biology, synthetic chemistry, molecular and cell biology together with genomics.';2499107;2499107;ERC-2013-ADG;/ERC-AG;THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;UK;;;"/BIO;/LIF";1;0;0;1;0;0 109202;329044;MECHACOMPA;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IEF;FP7;Mechanics of compaction in the mouse pre-implantation embryo;2014-07-01;2016-06-30;;"Compaction is the earliest morphogenetic event in mouse embryonic development during which blastomeres increase the size of their cell-cell interfaces. This permits the establishment of apico-basal polarity and thereby the 1st fate specification of the blastomeres: trophectoderm derives from blastomeres with a large apical membrane at the cell-medium interface; whereas blastomeres composing the inner cell mass descend from cells with comparably larger basal cell-cell interfaces. Essential molecules regulating compaction were identified; among them are cell-cell adhesion and cytoskeletal components. However, the precise mechanism by which these molecules drive compaction is not yet understood. In particular, the forces and mechanical properties associated with adhesive and cytoskeletal components that are responsible for the embryo shape change remain uncharacterized. Combining biophysical methods and high-resolution microscopy, we aim to characterize cells mechanical properties and underlying molecules that control compaction. We will monitor, using micropipette aspiration techniques, the contractile and adhesive properties of mouse blastomeres during compaction. In addition, we will quantitatively track changes in cell shape and reorganization of key molecules. With this, we will build a spatio-temporal map of the mechanical properties during compaction. This interdisciplinary and quantitative approach will be key to build a comprehensive model of compaction in early mammalian development.";161968,8;161968,8;FP7-PEOPLE-2012-IEF;/MC-IEF;EUROPEAN MOLECULAR BIOLOGY LABORATORY;DE;;;/SCI;1;0;0;1;0;0 109796;609850;CHIMERA;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IRSES;FP7;Binding-activated fluorescent DNA/peptide chimeric probes for cancer imaging;2013-11-01;2016-10-31;;The overriding goal of this project is to mimic Nature in the design of novel nucleic acid/peptide chimera based nanodevices that can enable cancer imaging. We will design, engineer and optimize highly specific biomolecular nanodevices that undergo binding-induced conformational changes upon target binding and, in doing so, signal the presence of the cancer marker. This scientific goal of great relevance for the clinical implications will be achieved bringing together an international and interdisciplinary group of research teams and building a collaborative environment for research, innovation and technology transfer. This program will allow the exchange of knowledge and expertise through visiting training periods for participating early-stage and experienced researchers. The training will involve each single aspect of probe development and cancer imaging. The research teams involved in this project encompass the requisite expertise and each of them has a particular focus on a single step of optical probe development and testing on cancer cells. This program will help the integration and collaboration among the research teams and the establishment of a long-term collaboration between Europe and key Third Countries.;119700;119700;FP7-PEOPLE-2013-IRSES;/MC-IRSES;UNIVERSITA DEGLI STUDI DI ROMA TORVERGATA;IT;TARTU ULIKOOL;EE;/LIF;1;0;0;1;0;0 108549;328673;BLASTOHIT2012;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IEF;FP7;Clarifying the role of Blastocystis in human intestinal disease;2013-09-13;2016-03-12;;"It is now realised that the human intestinal microbiota is central to health and wellbeing. However, the vast amount of research into the human microbiome has focused primarily on the prokaryotic (bacterial) component of this complex microbial ecosystem and we understand virtually nothing of the eukaryotic species, such as the protists, that are known to play critical roles in structuring microbial communities in other natural ecosystems. Blastocystis is the most common protist in the human intestinal tract (IT); current estimates indicate that it colonises up to 1 billion people worldwide. Crucially, Blastocystis is considered to be an emerging pathogen, but its role in human illness and disease is both controversial and unclear. The key research goal of this project is to clarify the role of Blastocystis in human intestinal health and disease. For this project there will be a specific focus on Irritable Bowel Syndrome (IBS). We will analyse the prevalence and genetic diversity of Blastocystis in IBS together with healthy individuals and study the interactions between Blastocystis and specific intestinal bacteria. We will use an integrated series of state-of-the-art experiments encompassing both quantitative and qualitative analysis. These include a novel high-throughput PCR with high genetic resolution to assess Blastocystis variation in IBS and healthy groups, next-generation sequence analysis of IT bacteria, quantitative PCR, virulence assays, in vitro microcosm experiments and phenotypic assays. The novel interdisciplinary framework outlined in this proposal that combines molecular microbial surveys of the human IT with experimental microbial ecology and evolution, will allow us to address unresolved and original research questions. Data from this study also has the potential for commercialisation including the development of novel therapeutic treatments.";246782,6;246782,6;FP7-PEOPLE-2012-IEF;/MC-IEF;TEAGASC - AGRICULTURE AND FOOD DEVELOPMENT AUTHORITY;IE;;;/SCI;1;0;0;1;0;0 111219;613318;CARE;ONG;FP7-SSH;SSH.2013.3.2-2;FP7;Curriculum Quality Analysis and Impact Review of European ECEC;2014-01-01;2016-12-31;;"In line with the EU strategies for 2020 and the need for a systemic and integrated approach to Early Childhood education and Care (ECEC), the project identifies eight key issues and questions for which effective policy measures and instruments should be developed. They concern assessing the impact of ECEC, optimizing quality and curricula for ECEC to increase effectiveness, raising the professional competencies of staff, monitoring and assuring quality of ECEC, increasing the inclusiveness of ECEC, in particular for socioeconomically disadvantaged children, funding of ECEC, and the need for innovative European indicators of children’s wellbeing. The project will address these issues in an integrative way by combining state-of-the-art knowledge of factors determining personal, social and economic benefits of ECEC with knowledge of the mechanisms determining access to and use of ECEC. In developing a European knowledge base for ECEC, we will add to the existing knowledge in two ways. First, we will include recent and ongoing ECEC research from several European countries. Second, we will include the perspectives of important stakeholders and integrate cultural beliefs and values. The central aim is to develop an evidence-based and culture-sensitive framework of (a) Developmental goals, quality assessment, curriculum approaches and policy measures for improving the quality and effectiveness of ECEC; and (b) Effective strategies of organizing, funding and governing ECEC that increase the impact of ECEC. Our interdisciplinary research team will construct this framework, based on the competencies and skills that young children need to develop in current societies, identify the conditions that have to be fulfilled to promote child development and wellbeing, and identify strategies and policy measures that support access to high quality provisions, and likely to receive broad support of stakeholders, thereby enhancing the impact of ECEC.";3285284;2498607;FP7-SSH-2013-2;/CP-FP;UNIVERSITEIT UTRECHT;NL;"AARHUS UNIVERSITET;UNIWERSYTET WARSZAWSKI;HOGSKOLEN I SOROST-NORGE;HOGSKOLEN I BUSKERUD OG VESTFOLD;INSTITUTO UNIVERSITARIO DE LISBOA;JYVASKYLAN YLIOPISTO;HOGSKOLEN I VESTFOLD;UNIVERSITA' DEGLI STUDI DI MILANO-BICOCCA;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;KATHOLIEKE UNIVERSITEIT LEUVEN;FREIE UNIVERSITAET BERLIN;HELLENIC OPEN UNIVERSITY";"DK;PL;NO;PT;FI;IT;UK;BE;DE;EL";"/SOC;/POL";1;0;0;1;0;0 92674;238710;MC IMPULSE;ONG;FP7-PEOPLE;FP7-PEOPLE-ITN-2008;FP7;European Research Training in Monte Carlo based Innovative Management and Processing for an Unrivalled Leap in Sensor Exploitation;2009-12-01;2014-02-28;;Sensor technology has become ubiquitous in almost every area of our daily life. Its application has the potential to significantly improve our quality of life, for example through systems for independent living (ambient assisted living) or accident prevention in traffic. The MC IMPULSE consortium has identified sensor data processing as a key technological area where Europe can make a difference. Additional investment in research and technological development, training of researchers and networking the existing research capacities both in academia and industry are prerequisites for success. MC IMPULSE exactly aims at these strategic objectives. MC IMPULSE aims to develop and execute a multidisciplinary and networked European research training programme. To date no specific training programme in this field is available in Europe while well trained researchers and engineers are scarce. The MC IMPULSE consortium unites highly complementary partners from industry (including Thales, Saab and 2 SME’s) universities and a research institute, guaranteeing an interdisciplinary research and training programme. Within MC IMPULSE 13 early stage researchers and two experienced researchers will be trained. The MC IMPULSE consortium will build a durable cooperation in research and training in the field of sensor data processing. The research programme will focus on the development of novel methods for real-time signal and data processing, based on data collected form sensors or networks of sensors. Specific innovations expected to be achieved through MC IMPULSE are: • detecting and tracking objects by processing information from (a network of) sensors, • fusing information from multiple sensors and their efficient processing for on-line applications. Dissemination methods to realize optimal impact on the European academic community, industry and society include scientific publications, presentations at conferences and dissemination through websites.;3315000;3315000;FP7-PEOPLE-ITN-2008;/MC-ITN;THALES NEDERLAND BV;NL;"LINKOPINGS UNIVERSITET;SAAB AKTIEBOLAG;FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.;UNIVERSITEIT TWENTE;RINICOM LIMITED;XSENS HOLDING B.V.;LANCASTER UNIVERSITY";"SE;DE;NL;UK";"/SCI;/EDU";1;0;0;1;0;0 99280;277078;RETROMER;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-RG;FP7;The mechanism of retrograde trafficking by retromer;2011-03-01;2015-02-28;;"Transportation of proteins and lipids between membrane-enclosed organelles by vesicle formation is a fundamental task in eukaryote cells. The least understood protein complex involved in membrane remodelling for vesiculation, but with a wide range of medical implications, is the retromer complex. The objective of this proposal is: First, to identify the mechanistic principles of membrane bending and scission by retromer, and second to characterize temporal and morphological aspects of retromer and cargo molecules (Shiga toxin (STx) and Alzheimer’s amyloid-beta-cleaving enzyme (BACE)). I will exploit two approaches: First, in vitro reconstitution of the retromer complex using giant unilamellar vesicles to deploy biophysical methods. Second, I will provide a molecular choreography and anatomy of retrograde transport of STx, BACE and retromer by implementing a new imaging technique, structured-illumination microscopy combined with single particle tracking. The proposed interdisciplinary research will break new ground for membrane mechanics and trafficking of disease related cargo molecules.";100000;100000;FP7-PEOPLE-2010-RG;/MC-IRG;INSTITUT CURIE;FR;;;/SCI;1;0;0;1;0;0 111174;339828;DIGMEDTEXT;ONG;FP7-IDEAS-ERC;ERC-AG-SH5;FP7;Online Humanities Scholarship: A Digital Medical Library based on Ancient Texts;2014-01-01;2016-12-31;;'The project aims at providing electronic editions of ancient medical sources including texts, translations, commentary, metadata, and images of papyri, ostraca, and tablets. Greek medical papyri and related artifacts recovered in Egypt are a veritable treasure trove of information on crucial and otherwise poorly attested phases in the development of ancient Greek medicine, its penetration into regions of the Mediterranean world and its transformation through interaction with local medical traditions — a medicine that Romans spread throughout western Europe. The interdisciplinary approach makes possible cooperative interaction among classicists, information technicians, ancient historians, and especially historians of medicine. The goal is to make both texts and metadata accessible via a single interface and to publish texts online, combining philological rigour with technological flexibility, bibliographic control, and a critical apparatus for each text. Openness and dynamism will characterise our searchable database: it is not to be a synthesis of fixed data, but rather a constantly changing repertory of sources monitored by the scholarly community and maintained by those who wish to participate at a professional level. It will extend the Duke Data Bank, taking the latter in new directions by uniting documentary and literary papyri into a common technological framework — SoSOL within Digital Papyrology. The central feature is interaction by the worldwide community of coopted participants manipulating electronic means to produce new editions of previously unknown literary and paraliterary texts of medical content, as well as to improve existing editions. The Medical Library will share space with a dictionary of technical terms attested in the papyri that likewise survive into modern scientific discourse. The entire community of papyrologists, ancient historians, historians of science, philologists, and digital humanists will share in the results.';654836;654836;ERC-2013-ADG;/ERC-AG;UNIVERSITA DEGLI STUDI DI PARMA;IT;;;/SOC;1;0;0;1;0;0 110142;602262;IACT;ONG;FP7-HEALTH;HEALTH.2013.2.4.1-2;FP7;Immunostimulatory Agonist antibodies for Cancer Therapy;2013-11-01;2017-10-31;;"'This concerted action aims at providing new treatment options for cancer patients through boosting innovative drug development by European academia and industry. A wealth of preclinical data shows that the therapeutic impact of cytotoxic regimens is enhanced by simultaneous application of drugs that strengthen the immune system. The recent FDA-approval of Ipilimumab demonstrated that cancer immunotherapeutics constitute a clinically effective, marketable drug concept. Ipilimumab is an antagonist immunostimulatory antibody (IS-Ab) that removes the restraint on the immune response by blocking inhibitory receptors on immune cells. Potent immunity can also be elicited by means of agonist IS-Abs that engage activatory receptors. Our program will translate the agonist IS-Ab concept into clinical treatments. This is critical, because a repertoire of complementary drugs that act at different points in the immune regulatory network will be required to counter immune failure in different cancer (sub-)types. Our initiative is supported by longstanding experience as well as by the availability of clinical lead Abs. Pivotal are two clinical trials in which cancer type and treatment regimen have been selected to approximate pre-clinical settings in which striking therapeutic impact with agonist IS-Abs has been obtained. These studies will involve extensive analysis of efficacy-related biomarkers by means of validated assays, not only in blood samples, but also in the most relevant compartment: the tumor microenvironment. While our state-of-the-art agonist IS-Abs are being tested in the clinic, a parallel SME-driven effort will aim at the development of 2nd generation agonist IS-Abs with superior therapeutic index. This innovation is supported by proprietary technology and will result in intellectual property and marketable drugs. Taken together, our interdisciplinary platform is designed to yield maximal benefit for health care, academia and health-related industries in Europe.'";8227907,6;5995747;FP7-HEALTH-2013-INNOVATION-1;/CP-FP;DEUTSCHES KREBSFORSCHUNGSZENTRUM HEIDELBERG;DE;"BIONTECH RNA PHARMACEUTICALS GMBH;FUNDACION PARA LA INVESTIGACION MEDICA APLICADA FIMA;UNIVERSIDAD DE NAVARRA;UNIVERSITY OF SOUTHAMPTON;BIOINVENT INTERNATIONAL AB;GLYCOTOPE GMBH;UNIVERSITAETSKLINIKUM HEIDELBERG;FONDAZIONE IRCCS ISTITUTO NAZIONALE DEI TUMORI;LEADARTIS S.L.";"DE;ES;UK;SE;IT";/LIF;1;0;0;1;0;0 96287;268429;MAARITIME;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-RG;FP7;Marine Amino Acid Racemisation Investigation of the Mediterranean;2010-10-01;2013-09-30;;"mAARiTIME is a highly interdisciplinary project, which brings together the fields of Archaeology, Biology, Chemistry, Geochronology and Quaternary Sciences. Through protein geochronology (amino acid racemisation dating, AAR), it seeks to answer two specific but vital questions: when did early humans become “modern”, and is “modern” behaviour unique to our own species? Behavioural modernity has fortuitously left traces in the archaeological record as molluscan remains, one of the best substrates for AAR dating. Molluscs were exploited as a food resource and shells were used as personal ornaments, providing some of the earliest evidence of symbolic thinking displayed by early humans. These appear between 160-70 ka ago, a period which falls tantalisingly outside that of many commonly applied dating techniques. AAR is able to yield direct age information for mollusc shells, and its broad temporal span (the whole Quaternary, 0-2.6 Ma) makes it the ideal method for framing chronologically the debate over the origins of modern human behaviour. mAARiTIME will focus on the Mediterranean rim, which is key to the development of behavioural modernity. By applying a novel (closed-system) method of AAR dating, mAARiTIME will build chronological frameworks able to provide reliable dating control for this area. The method will be rigorously tested by laboratory experiments on different molluscan taxa as well as by comparing the AAR data with independent age information. A detailed investigation of protein breakdown will also be performed by applying state-of-the-art proteomics and imaging techniques. Other than producing important advances in geochronology and archaeological sciences, mAARiTIME will enable the development of long-lasting collaboration between a network of researchers in Northern and Southern Europe, coordinated by the applicant, and with the long-term goal of establishing a AAR dating facility in Southern Europe.";45000;45000;FP7-PEOPLE-2010-RG;/MC-ERG;UNIVERSITY OF YORK;UK;;;/SCI;1;0;0;1;0;0 109203;329423;TREPAPHEN;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IEF;FP7;Early treated patients with PKU: Exploring the association between measures of metabolic control, cognitive performance and neurological health;2013-09-16;2015-09-15;http://www.aston.ac.uk/lhs/staff/az-index/liana-palermo/trepaphen/;Phenylketonuria (PKU) is an inherited metabolic disease which, if left untreated, results in severe mental retardation. The main symptoms can be eliminated by following a restrictive and unpleasant diet, but it is unclear whether this diet should be maintained after childhood. The research team for TREPAPHEN is treating one of the largest cohorts of PKU patients in the UK with records of blood levels of Phe since infancy. These patients are the first generation to reach adulthood after treatment allowing, for the first time, assessment of whether, even in adulthood, high levels of Phe have a significant negative impact on brain functions and cognitive performance. TREPAPHEN will carry out an in-depth assessment of the cognitive performance of these patients in critical target areas and relate it not only to adult blood levels of Phe but also to measures of brain functions at different levels (structural, neurological and metabolic). The assessment of associations amongst cognitive, neurological and metabolic measures will enable an unprecedented level of understanding of this disorder, tracking the difficulties experienced by patients from the biological to the behavioural level. This will answer the question of whether or not adult patients should maintain a strict diet, a controversial policy issue across European Health Services. TREPAPHEN will bring together a talented young fellow, with a background in neuropsychology, an internationally excellent, interdisciplinary group with expertise in neuropsychological assessments, neuroimaging and clinical care of patients with metabolic disorders and a valuable cohort of patients with complete histories of Phe levels. Following this fellowship, the applicant will be an extremely sought after asset to European research with a unique set of skills in the theoretical understanding of cognitive impairments, their evaluation and the analysis of their biological correlates which can be used to study other patient groups.;221606,4;221606,4;FP7-PEOPLE-2012-IEF;/MC-IEF;ASTON UNIVERSITY;UK;;;/SCI;1;0;0;1;0;0 97994;263506;AFFECTS;ONG;FP7-SPACE;SPA.2010.2.3-1;FP7;Advanced Forecast For Ensuring Communications Through Space;2011-03-01;2014-02-28;http://www.affects-fp7.eu;In this call the EU supports activities strengthening space foundations reducing the vulnerability of space assets from space weather events. Solar activity affects the entire Earth environment from the magnetosphere down to the ionosphere and even to the lower atmosphere climate system. The natural hazards of space weather do not only modify the atmosphere but also can catastrophically disrupt the operations of many technological systems, thus causing disruption to people's lives and jobs. The AFFECTS collaborative project uniquely addresses these key topics through state of the art analysis and modeling of the Sun-Earth Chain of Effects on the Earth's ionosphere and their subsequent impacts on communication systems. Multipoint space observations enable world-leading experts at the highest level of interdisciplinary excellence to forecast the relevant space weather effects on the ionosphere quantitatively. The unique set of measurements from satellites in different orbits is complemented by dedicated ground-based monitoring of auroral electrojet and ionospheric activity. The AFFECTS team consists of key European space weather research teams and the US Space Weather Prediction Center of NOAA. To date no dedicated space weather forecast system for ionospheric applications exists in an operational manner, and thus this project would lead to an entirely new capability in Europe that is not only important for society but also does not exist elsewhere. AFFECTS is an unprecedented project which in time of the expected next solar maximum around 2012 will provide advanced prediction, assessment and early warning capabilities of disruptive space weather events that are expected to be particularly poignant to society and thereby meets the needs of Europe’s community of users. AFFECTS will provide Europe with the first advanced early warning and space weather forecast system to help European citizens mitigating the impact on its communication systems.;2550245;1999893;FP7-SPACE-2010-1;/CP;GEORG-AUGUST-UNIVERSITAT GOTTINGENSTIFTUNG OFFENTLICHEN RECHTS;DE;"UNIVERSITETET I TROMSOE;FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.;DEUTSCHES ZENTRUM FUER LUFT - UND RAUMFAHRT EV;KONINKLIJKE STERRENWACHT VAN BELGIE;SPACE RESEARCH INSTITUTE OF THE NATIONAL ACADEMY OF SCIENCES OF UKRAINE AND THE NATIONAL SPACE AGENCY OF UKRAINE;AIRBUS DS GMBH";"NO;DE;BE;UA";"/SPA;/SEC";1;0;0;1;0;0 93461;240816;QUANTHISTLING;ONG;FP7-IDEAS-ERC;ERC-SG-SH4;FP7;Quantitative modeling of historical-comparative linguistics: Unraveling the phylogeny of native South American languages;2010-01-01;2014-12-31;;This project aims to uncover and clarify phylogenetic relationships between native South American languages. Very little is known about the historical development of the linguistic diversity in this part of the world, and more detailed insights will have a major impact not only on linguistics, but also on genetics, archeology, and cultural anthropology. The approach taken is to digitize available lexical information about the languages in question, and to develop new and innovative computer-assisted methods to quantify the analysis of this information. This quantification will be based on the techniques and experiences of the traditional historical-comparative method, and not use the Swadesh-style approach using wordlists. This novel quantitative approach makes it possible to process more data in a more consistent and faster manner, and as a consequence uncover more evidence for genealogical relations. The availability of more evidence is essential to push back the phylogenetic time-depth beyond the few thousand years to which historical linguistics is traditionally limited. A second key objective of this project is to transform historical-comparative linguistics from a primarily handcrafted scholarly endeavor, performed by individual researchers, into a quantitative and collaborative field of research, involving linguists, mathematicians and computer scientists alike. The project will build a truly interdisciplinary team to improve the interaction between linguistics and mathematics. In this way, not just historical linguistics will profit from methods and insights previously developed in mathematics and computer science, but the special requirements posed by language variation and language change will also reframe and further extend current phylogenetic methods.;1938000;1938000;ERC-2009-StG;/ERC-SG;PHILIPPS UNIVERSITAET MARBURG;DE;LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN;DE;/SOC;1;0;0;1;0;0 89758;230268;MORPHOLOGY;ONG;FP7-IDEAS-ERC;ERC-AG-SH4;FP7;Morphological Complexity: Typology as a Tool for Delineating Cognitive Organization;2009-02-01;2015-01-31;;Charting the limits of linguistic complexity will open up new perspectives for researching both language and the human mind. We focus on inflectional morphology, which is the systematic manipulation of word forms to express grammatical meaning. As a uniquely linguistic and uniquely human component of communication, morphology stands to reveal otherwise inaccessible aspects of cognition. Morphological systems introduce an extra layer of structure in between meaning and its expression. This layer may operate at cross purposes to functional distinctions, attaining in some languages an astonishing degree of complexity. Such apparently arbitrary distinctions in form (inflection classes, irregularity and similar phenomena) are the particular focus of this project. They are a key resource for understanding mental processes as they represent an unconscious and yet highly structured autonomous system. The project core is a comprehensive typological and historical investigation of morphological complexity (surveying 200 languages), with input from psycholinguistic and computational methodology. Such an interdisciplinary approach has not been attempted before. A deeper understanding of morphological complexity, a component of language which is free of the functional, physiological and sociological constraints that normally shape other linguistic structures, promises to advance both linguistic theory in particular, and the cognitive sciences as a whole.;1712538;1712538;ERC-2008-AdG;/ERC-AG;UNIVERSITY OF SURREY;UK;UNIVERSITY OF YORK;UK;/MED;1;0;0;1;0;0 99207;267117;DARK;ONG;FP7-IDEAS-ERC;ERC-AG-PE9;FP7;Dark Matters;2011-06-01;2017-05-31;;This interdisciplinary proposal spans theoretical astrophysics and particle physics by addressing the need to provide astrophysical expertise to the particle astrophysics community in the area of dark matter and dark energy research. A new dialogue will be developed via collaborations involving expertise in astronomy, statistics and particle physics that centre on fundamental aspects of the nature of the contents of the universe. Theoretical predictions will be refined to pursue the quest for dark matter using novel experiments designed to detect the direct signatures of dark matter in our galactic halo via scattering and indirect via annihilations into high energy particles and photons. Dark matter and dark energy will be studied by cosmic microwave background temperature fluctuations and structure formation constraints. The former probe is contaminated by inadequately understood foregrounds that will be examined to extract clues to new physics in the very early universe, an especially timely research frontier in view of the anticipated data from the Planck satellite. The latter is rendered difficult by the highly complex interface of star and galaxy formation. This will be studied by emphasizing development of feedback prescriptions, an ingredient that plays a central role in the current paradigm for galaxy formation and complements ultradeep searches with the new generation of telescopes. The overall goal, namely to leverage via theory on the unprecedented experimental efforts that are underway to address dark sector issues in the emerging field of particle astrophysics, is achievable at relatively modest cost.;2499990;2499990;ERC-2010-AdG_20100224;/ERC-AG;UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6;FR;UNIVERSITY OF DURHAM;UK;"/PSE;/AER;/SPA";1;0;0;1;0;0 103170;299251;IMTRAP;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IOF;FP7;Integration of Machine Translation Paradigms;2012-12-07;2016-10-28;http://www.costa-jussa.com/projects/past/imtrap/;"Machine Translation (MT) is a highly interdisciplinary and multidisciplinary field since it is approached from the point of view of engineering, computer science, informatics, statistics and linguists. Unfortunately, the cooperation and interaction among these fields in relation to MT technologies is still very low. The goal of this research project is to approach the different profiles in the MT community by providing a new integrated MT paradigm which mainly includes linguistic technologies and statistical algorithms. Basically, our research will be focused on the problem of dynamically integrating the two most popular MT paradigms: the rule-based and the statistical-based. We will use linguistic technologies developed either for the rule-based MT systems or other natural language processing tasks into statistical MT systems. Linguistic technologies include: bilingual dictionaries, transfer rules, statistical parsing, word sense disambiguation, morphological and syntactic analysis. The new paradigm will provide solutions to current MT challenges such as unknown words, reordering and semantic ambiguities. The project will focus on the three most spoken languages in the world: Chinese, Spanish and English; and all translation combinations among them. These language pairs do not only involve many economical and cultural interests, but they also include some of the most relevant MT challenges such as morphological, syntactic and semantic variations.";173212,8;173212,8;FP7-PEOPLE-2011-IOF;/MC-IOF;UNIVERSITAT POLITECNICA DE CATALUNYA;ES;;;/SCI;1;0;0;1;0;0 98839;268930;RUBINET;ONG;FP7-IDEAS-ERC;ERC-AG-LS3;FP7;Regulation of cell growth and division by selective degradation mechanisms;2011-05-01;2016-04-30;;"Cell growth and division are tightly regulated by phosphorylation and selective degradation of cellular components. Whereas autophagy is mainly responsible to eliminate long-lived proteins and organelles, the ubiquitin-proteasome system (UPS) rapidly degrades proteins when fast adaptation is needed. Defects in these degradation systems accounts for numerous human diseases, including cancer, muscle dystrophies, viral and bacterial infections and neurodegeneration. While rapid progress has been made in the identification of UPS and autophagy components, little is known about their regulation and the molecular mechanisms that ensure substrate specificity. We therefore propose an interdisciplinary combination of biochemistry, cell and structural biology, genetics, RNAi-screening, quantitative microscopy and microfluidic technology to tackle these questions in yeast and mammalian cells. E3 ubiquitin ligase complexes are important UPS components that specifically bind substrates via dedicated adaptors. In particular, cullin-based E3-ligases control cell growth and division, but much needs to be learned about their regulation and the identity and function of their key substrates. Moreover, we uncovered a function of RING-H2 E3-ligases in MAP-kinase networks, providing a new link between phosphorylation and the UPS. Finally, while autophagy can selectively remove protein aggregates and damaged or excess organelles, the underlying mechanisms that provide specificity to this process are poorly understood. Recent evidence suggests that ubiquitin may also serve as a recognition signal for selective autophagy. We will thus investigate the roles of ubiquitin and specific autophagy substrate-adaptors, and focus on the molecular crosstalk between selective autophagy and the UPS.";2426976;2426976;ERC-2010-AdG_20100317;/ERC-AG;EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH;CH;;;"/BIO;/LIF";1;0;0;1;0;0 102455;297903;LimitGroups;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IIF;FP7;Limit Groups over Partially Commutative Groups;2013-02-01;2015-01-31;;"Klein proposed Group Theory as a means of formulating and understanding geometrical constructions. Geometric Group Theory embraces this approach and also reverses it by using geometrical ideas to give new insights into central problems in Group Theory. In the last decades, it has become a nexus between several branches of mathematics such as Geometry, Model Theory, Dynamical Systems and Algebraic Geometry over Groups. One of the most representative exponents of this interdisciplinary connection is the theory of limit groups. This theory played a crucial role in the recent solution of the famous Tarski problems and revealed a beautiful and deep relation with the theories of JSJ decompositions and very small actions on real trees. As the geometry of free groups is associated to trees, the geometry of partially commutative groups is associated to higher-dimensional analogues of trees. Partially commutative groups are not simply generalisations of free groups, they appear naturally in many different branches of mathematics as well as in computer science, robotics and theoretical physics. This project aims at developing a theory of limit groups over partially commutative groups from algebraic, geometric, algorithmic and model theoretic viewpoints. It intends to explore and strengthen the interconnection between the aforementioned branches of mathematics and to open up directions for further research in each of them.";200371,8;200371,8;FP7-PEOPLE-2011-IIF;/MC-IIF;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;UK;;;/SCI;1;0;0;1;0;0 108286;332276;FABRIC OF LIFE;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IOF;FP7;Power networks and fractured modernities: a political history and geography of electrification in Palestine-Israel;2014-02-01;2017-01-31;;"This research project investigates the ways in which electrification, and the ‘roll out’ of electricity infrastructures, comes to matter socially, politically, economically and spatially both symbolically and as a set of materials. An interdisciplinary analytical focus on how these ‘large technical systems’ are constructed and used in Palestine-Israel offers a powerful way of thinking about electricity as a complex assemblage of actors, agents and processes that connect to, and drive, much debated processes of colonialism, modernity, statecraft and uneven development. The focus on electricity brings an unexplored and fascinating reading of the past and present history of Palestine-Israel. Drawing on insights from a variety of disciplinary perspectives –ranging from social studies of technology, urban studies or political economy to postcolonial studies— this project seeks to: (a) document, analyze and produce an innovative history of Palestine-Israel in which electrification and the development of electricity grids play a central role in directing, organizing and shaping space and everyday life; (b) address the actual theoretical and empirical lacunae on electrification and electricity infrastructure in both Middle East Studies and social science research focusing on infrastructure; and (c) develop a conceptualization of electricity that destabilizes and reconfigures existing boundaries between technology and society, the material and the symbolic or the human and non human and how this particular electric assemblage is territorialized in Palestine-Israel. The approach advanced in this project provides a timely corrective to area studies –Middle East and Palestine-Israel—largely defined (understandably) by geopolitics and violence, offering instead an approach that allows for careful consideration of what might be learned from the seemingly mundane ‘things’ that still today connect (albeit selectively) spaces and populations otherwise increasingly divided.";267551,4;267551,4;FP7-PEOPLE-2012-IOF;/MC-IOF;UNIVERSITEIT GENT;BE;;;/LIF;1;0;0;1;0;0 96297;251714;SEMCMER;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IOF;FP7;Sex in the Early Modern City: Musical Eroticism in Rome;2011-06-16;2014-12-19;;"This project examines the role of music in Rome in creating, circulating, reinforcing, policing and subverting norms of gender and sexuality. The methods by which sexuality and the erotic are transmitted by music (of any age) are not wholly understood; through this investigation we learn more about the affective nature of music, and how music can be used as a political and cultural tool. The research identifies eroticism in music in secular song, drawing on madrigals as well as a repertory of strophic song that is marginal within the discipline of musicology, and then, with reference to settings of the Song of Songs and to the liturgy of women saints, explores eroticism in sacred music. A key aspect is the examination of how early modern women and men interacted with music and fashioned diverse identities that were distinguished by class, ethnicity, race, region, religion, gender, and sexuality. The project argues that some aspects of the European project originate in early modern history. The project promotes awareness and understanding of diversity in the history of gender and sexualities and responds to European legislation against discrimination. It is vital to make clear the long history of sexual diversity in Europe, and the long history of music’s role in sexualities, as a means to work against discrimination on grounds of sexuality and to support and encourage a healthy attitude to diversity. This project will be carried out in Los Angeles, New York and Cork. The initial stage of data collection and analysis will take 12 months, with the remaining 24 months spent writing and developing a monograph, hosting an international, interdisciplinary conference in Europe and developing advance research training networks.";242121,7;242121,7;FP7-PEOPLE-2009-IOF;/MC-IOF;UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK;IE;;;"/LIF;/EDU";1;0;0;1;0;0 99986;294236;INFLOW;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-CIG;FP7;Information Flow in Opportunistic Wireless Networks;2011-09-01;2016-05-10;;"The objective of INFLOW is to develop the methodology and algorithms for the modeling and analysis of optimal information flow in future wireless networks, thus leading to the design of new network protocols and algorithms. Building on recent breakthroughs in network information theory and in distributed systems, the aim is to leverage the potential of networks consisting essentially of wireless and mobile nodes. Advances in this area will have a significant impact on the possibilities of the future Internet. Portable devices with ubiquitous wireless connectivity have the potential to revolutionize the personal computing landscape, creating opportunities for unprecedented applications and services. But, standing in the way of this vision are challenges spanning the entire system architecture, due to the distinct characteristics of the wireless medium. To overcome such challenges, further research investigations focused on the understanding of the fundamental properties of complex wireless systems are needed. The first goal consists in pushing the theoretical performance limits of mobile and wireless networks, taking into account the state of the art results in network information theory, and thus focusing on two emerging key principles: opportunistic networking and network coding. Thus, we propose to study dynamically changing networks, i.e., networks where the structure, topology, and demands may vary in a short time scale as compared to the information transfer. The proposed interdisciplinary approach draws on advanced mathematical models, founded on information theory, stochastic analysis, the techniques developed for the analysis of algorithms, and statistical physics inspired methods to study the emerging behavior of large-scale networks. But, the goal is to deliver practical network solutions, in the form of new protocols, architectures and algorithms, which are derived from the insights provided by the modeling analysis, and offer optimized performance.";100000;100000;FP7-PEOPLE-2011-CIG;/MC-CIG;ETHNIKO KENTRO EREVNAS KAI TECHNOLOGIKIS ANAPTYXIS;EL;;;/SCI;1;0;0;1;0;0 109599;612263;NETEP;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IRSES;FP7;NETEP—European-Brazilian Network on Energy Planning;2014-01-02;2017-01-01;;The general aim of the propose NETEP—European-Brazilian Network on Energy Planning is to create the basis for interdisciplinary research and knowledge transfer on energy planning. The proposed exchange programme envisages a significant contribution to the development of sustainable energy planning strategies that will support future decision making. NETEP brings together partners having different types of expertise in the field of energy analysis and operating in four different countries: Portugal, UK, Spain and Brazil expressing different energetic metabolic patterns and different energy market structures. Staff exchange will enable partners to share knowledge on models and methodologies and on the possibility of implementing or adapting them to different energy systems. The knowledge generated will benefit energy decision makers and the scientific community. The outputs will result in a relevant contribution to the general target of achieving sustainable energy societies in the future. Visits between universities’ research staff are expected to create the basis for proposing joint projects and long term collaboration. The participation and training of early career researchers is a key aspect of the proposal and joint supervision of their work will be valuable means to ensure proper collaboration and knowledge transfer between EU and Brazil.;218400;218400;FP7-PEOPLE-2013-IRSES;/MC-IRSES;UNIVERSIDADE DO MINHO;PT;"UNIVERSITAT AUTONOMA DE BARCELONA;CRANFIELD UNIVERSITY";"ES;UK";/LIF;1;0;0;1;0;0 96237;243593;COLLECTIVE;ONG;FP7-SME;SME-2;FP7;Emerging communities for collective innovation: ICT Operational tool and supporting methodologies for SME Associations;2010-01-01;2012-12-31;;"The pace of technological change is accelerating. Radical discontinuities seem to happen more frequently. This means that the useful lifespan of knowledge and capability is becoming shorter and that the obsolescence of knowledge/capability is increasingly the norm in innovation. For incremental innovation, specialisation is a winning strategy, but radical innovation requires an interdisciplinary approach and a diversity of knowledge base that in general SMEs struggle to access. COLLECTIVE aims at solving the major constraints of SMEs innovation (to achieve successful, repeated organizational innovation; access to learning and knowledge processing; access to cognitive diversity; have the possibility to be connected to foster collaborative projects) by feeding the innovation ecosystem, basing on 3 key-concepts: (a)communities become the new organisational unit of the innovation process and define the ecosystem of innovation; (b) generation of innovative ideas, new product development and diffusion of innovations are carried out in parallel by self-organising communities of different actors (i.e.: customers, suppliers, users, experts, social stakeholders); (c) the key aspect that will define success or failure in discontinuous innovation projects will be the amount of cognitive diversity that firms (or groups of) will be able to gather and manage. iCOMMUNITY ICT operational platform will be the backbone of this innovation ecosystem and will let SMEs and SMEAGs: (1) identify future emergent technological and economic trends/discontinuities by developing network-based approaches to early detect ‘weak signals’; (2) manage distributed intelligence and creativity in the process of new product development in order to individuate new product ideas and related business models; (3) design new modular products in a collaborative way reducing the market risk since relevant inputs and feedback from customers and end users will be constantly ‘embedded’ in the design process.";3669878,18;2640000;FP7-SME-2008-2;/BSG-SME-AG;UNIVERSITA DEGLI STUDI DI UDINE;IT;"CONFEDERATION GENERALE DES PETITESET MOYENNES ENTREPRISES;TECHIN SPOLKA Z OGRANICZONA ODPOWIEDZIALNOSCIA;CAMERA DI COMMERCIO, INDUSTRIA, ARTIGIANATO E AGRICOLTURA DI MILANO;THE UNIVERSITY OF MANCHESTER;CHAMBER OF COMMERCE OF MACEDONIA ASSOCIATION;CYBION SRL;CAMPUS SRL;ASOCIACION PARA LA PROMOCION, INVESTIGACION, DESARROLLO E INNOVACION TECNOLOGICA DE LA INDUSTRIA DEL CALZADO Y CONEXAS DE LA RIOJA;STOWARZYSZENIE POLSKIEGO PRZEMYSLULOTNICZEGO;SINGULARLOGIC ANONYMI ETAIREIA PLIROFORIAKON SYSTIMATON KAI EFARMOGON PLIROFORIKIS;MATEMATICI SRL;UNIVERSITA DEGLI STUDI DI ROMA LA SAPIENZA;UNIVERZA V LJUBLJANI";"FR;PL;IT;UK;MK;ES;EL;SI";"/ECO;/SCI";1;0;0;1;0;0 96868;260895;PREDICTA;ONG;FP7-HEALTH;HEALTH.2010.2.4.5-2;FP7;Post-infectious immune reprogramming and its association with persistence and chronicity of respiratory allergic diseases;2010-10-01;2016-03-31;http://www.predicta.eu;"Chronic inflammatory diseases associated with allergy, including asthma and rhinitis, constitute a major and continuously growing public health concern for Europe. However, the causative factors and mechanisms converting a physiological inflammatory reaction to a chronic response triggering allergic disease remain elusive. Viral infections, particularly those caused by human rhinoviruses (RV) are the most frequent triggers of acute asthma exacerbations. RV infections have more recently been associated with asthma initiation; there is evidence suggesting that such infections may also contribute to respiratory allergy persistence. The strategic aims of PreDicta are to evaluate the hypothesis that repeated infections reprogram the immune system towards a persistent inflammatory pattern leading to respiratory allergies by (i) dissecting the molecular and cellular mechanisms involved in the lack of resolution of inflammation in the context of a human disease, (ii) identifying specific infectious agents and underlying altered host-pathogen interactions, and develop relevant prognostic and therapeutic strategies. PreDicta follows three interconnected workflows: models, mechanisms and translational output. Models include a longitudinal cohort in children, mouse models of repeated virus infection, primary epithelial cultures from patients, viral-bacterial interaction models, and models of epithelial-T-cell-dendritic cell interactions. These will be used to look into disease persistence, inflammation patterns, dysbiosis, immune regulation and resolution of inflammation. Translational outputs include prognostic use of subtype-specific antiviral antibodies, DNAZymes for therapeutic use and delivery technologies targeted to the bronchial epithelium. This interdisciplinary Consortium with strong track record, unique resources and strong translational focus, aims to produce new knowledge and technologies that can rapidly and effectively reach clinical care.";7862161,8;5991600;FP7-HEALTH-2010-single-stage;/CP-FP;ETHNIKO KAI KAPODISTRIAKO PANEPISTIMIO ATHINON;EL;"MEDIZINISCHE UNIVERSITAET WIEN;PHILIPPS UNIVERSITAET MARBURG;VARSINAIS-SUOMEN SAIRAANHOITOPIIRIN KUNTAYHTYMA;IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE;UNIVERSITEIT GENT;SCHWEIZERISCHES FORSCHUNGSINSTITUT FUER HOCHGEBIRGSKLIMA UND MEDIZIN IN DAVOS;IDRYMA IATROVIOLOGIKON EREUNON AKADEMIAS ATHINON;INSERM - TRANSFERT SA;UNIVERSYTET MEDYCZNY W LODZI.;UNIVERSITATSKLINIKUM ERLANGEN;BIOMAY AG;TURUN YLIOPISTO";"AT;DE;FI;UK;BE;CH;EL;FR;PL";"/MED;/MBI";1;0;0;1;0;0 107017;326398;SPATIAL ATTENTION;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IIF;FP7;Neural mechanisms underlying rapid modulation of spatial attention in cortex and superior colliculus;2014-01-01;2015-12-31;;"We are constantly inundated with a barrage of sensory information. At any given instant, however, only a small key fraction of this sensory world is relevant for taking action. Our brains must select out the critical input and use it to guide behavioral response. We often call this selection process attention. A field mouse, for example, scurrying through the grass scanning for delicious morsels attends to the ground below. The moment, however, the shadow of a hawk flashes by the mouse freezes in an instant attention was shifted from below to the imminent danger in the sky above. Attention is central to sensory processing and critical to survival. It is dynamically moved around to select the key sensory input. These changes in information selection occur extremely rapidly in the brain. This proposal aims to understand the cellular mechanisms driving this selection process. I develop a interdisciplinary approach using a novel spatial attention task in mice, and leverage this genetically tractable animal model, state-of-the art in vivo sub-cellular 2-photon imaging, optogenetics, & patch-clamp recordings to dissect the microcircuits & synaptic mechanisms that mediate these rapid changes in sensory processing. I will be hosted by Dr. Mainen at Portugal’s newly established Champalimaud Neuroscience Program. The systems neuroscience focus of the CNP, my past research experience, scientific interest & career goals makes this proposal the perfect match for both the host and I. This project will not only provide data on fundamental open questions regarding sensation & cognition, it will also allow me to develop a multidisciplinary approach to systems neuroscience. Combining sophisticated behavioral assays with next-gen techniques in optogenetics & imaging, this project puts the host lab and I at the bleeding-edge of systems neuroscience research. By funding this study, the Marie Curie Work Programme will secure its long-held leading role in supporting innovative research.";147210;147210;FP7-PEOPLE-2012-IIF;/MC-IIF;FUNDACAO D. ANNA SOMMER CHAMPALIMAUD E DR. CARLOS MONTEZ CHAMPALIMAUD;PT;;;/SCI;1;0;0;1;0;0 106394;300061;ECOFRUGAL;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IEF;FP7;The Economics of Frugality Between Ancient Rome and Contemporary Western Society;2013-01-01;2014-12-31;;"'The ECOFRUGAL project explores the relationship between ancient Roman values, behaviours, and laws regarding “material sobriety” and modern conceptions of such that have emerged in conjunction with the crisis now facing advanced capitalism. Using an interdisciplinary, comparative framework that draws on economic anthropology and cultural history, the project aims at a better understanding of Roman culture’s native concepts of frugality and a contextualization of “frugal” theories and practices now developing in Western political, economic, and social thought. Beginning with a lexicographic analysis of Roman concepts of “frugality” and an assessment of the impact of normative “frugal” values on the economic and cultural history of Rome (from the archaic age to the early empire), ECOFRUGAL goes on to articulate a more precise definition of the notions of frugality that have, in recent years, been at the centre of cultural and economic debate, especially in Western Europe. Through a cultural comparison between Roman models of behaviour concerning the limitation of material needs and desires – including their historical transformation – and contemporary Western notions of frugality, the project aims, in particular, to: First, increase significantly the field’s knowledge of the cultural codes according to which the Romans elaborated their conceptions of economy and of the historical dynamics of these conceptions; Second, better understand the relationship between Roman forms of materials sobriety and ideas of frugality that have emerged in the economic and socio-political thought of contemporary society; Third, re-evaluate Roman economic culture as a “resource of experience” for rethinking and thus understanding how the modern world can usefully re-appropriate ancient experience to resolve certain existing problems, and; Finally, to contribute to the intellectual profile of the European Research Area by engaging with a topic of such immediate societal relevance.'";209033,4;209033,4;FP7-PEOPLE-2011-IEF;/MC-IEF;THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;UK;;;/SCI;1;0;0;1;0;0 110549;329239;M-A-P-E-S;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IIF;FP7;Materiality and Affect in Public Engagement with Science;2013-11-01;2015-10-31;;"This project builds on work which has examined the European move towards public engagement with science and technology, and the ways in which the practice of participation is inflected by the cultures which surround it. However, its starting point is that there are important dimensions of engagement which have so far been ignored within analysis. It takes as its focus public engagement as a material, affective process, rather than one which is solely oriented around, and constituted through, ‘reasoned discourse’. In investigating this it will explore two research questions, asking: How can public engagement be re-conceptualised as material and affective practice? And: How can public engagement be studied as material and affective practice? Alongside a range of community-building activities designed to stimulate and solidify this emergent field of research, it will comprise phases of theoretical and empirical research. Fieldwork will involve a case study approach operationalised at a number of different levels: first, by taking Denmark as an exemplar of European best-practice in science communication and participation; second, by using the presence of the Euroscience Open Forum (ESOF) in Copenhagen in 2014 as a focal point for the research; and third, by selecting a set of events or processes which exemplify key traditions within European engagement practice. As a whole it will apply contemporary social and political theory on the importance of materiality and affect to the study of science and society. The project will enable the researcher to carry out a programme of innovative research at Copenhagen University, working with Maja Horst to develop new analyses of public participation with science and to solidify an emergent community of scholarship. Through a programme of research, practioner engagement, and interdisciplinary collaborative activities it will enable Davies to transfer knowledge from the USA to European scholarship in Science and Technology Studies.";221154,6;221154,6;FP7-PEOPLE-2012-IIF;/MC-IIF;KOBENHAVNS UNIVERSITET;DK;;;/SCI;1;0;0;1;0;0 93505;238486;INTRO;ONG;FP7-PEOPLE;FP7-PEOPLE-ITN-2008;FP7;INTeractive RObotics Research Network;2010-01-01;2013-12-31;;"The INTRO project – elaborated in close cooperation between universities and industry – will offer 10 young researchers (8 ESRs and 2 ERs) a unique training program to assist their career development in the interdisciplinary areas of Interactive Robotics: Cooperative Robot Learning; Cognitive Human-Robot Interaction (HRI) and Intelligent Interface Design. INTRO's overall objective is to contribute to create a new generation of researchers with a broad understanding of the research and technologies needed to build intelligent robots that function in close interaction with humans in unstructured, changing “real word” conditions. The research will develop the necessary foundations to expand robots into new markets by creating novel systems with cognitive and multi-modal interaction abilities. A strong multidisciplinary approach will complement specialized domain knowledge to enhance career prospects for the ESRs/ERs The industrial participation will endow the trainees with good insight into product life-cycle and provide unique training and valuable hands-on experience in top-level robotics development. There are four major components to the training program: in the Research program, each researcher will engage in an individual research project in close cooperation with well established researchers from the partner institutes. In addition, the research will be transferred to an operational platform in industry. A Joint training program will facilitate strong theoretical training. This includes a series of seminars and network-wide workshops. Each ESR will also undergo a Secondment and have short visits to other partners.. Other Network training activities will further strengthen the training program together with courses and activities providing complementary skills such as participation in project management, organization of workshops, presentation of research results, and courses in communication techniques, proposal writing , IPR etc.";2083328;2083328;FP7-PEOPLE-ITN-2008;/MC-ITN;UMEA UNIVERSITET;SE;"SPACE APPLICATIONS SERVICES NV;BEN-GURION UNIVERSITY OF THE NEGEV;UNIVERSITY OF THE WEST OF ENGLAND, BRISTOL;HUMBOLDT-UNIVERSITAET ZU BERLIN;ROBOSOFT Services Robots";"BE;IL;UK;DE;FR";"/SCI;/EDU";1;0;0;1;0;0 95385;251649;SMARTSOCKET;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IAPP;FP7;Intelligent amputee sockets employing real time advanced photonic sensors for optimum fit and pressure relief through active controls;2010-06-01;2014-05-31;;SmartSOCKET aims at realizing an intelligent amputee socket with optimum fitting and pressure relief utilizing embedded fiber sensors for strain/shear measurement and countershear actuators for readjusting the pressure map distribution across the knee-socket interface. SmartSOCKET will be the first project addressing fiber sensing configurations in true rehabilitation and biomechanic applications, intending to exploit the advantages of real-time and high-accuracy sensing capabilities of optical fiber structures towards equipping amputee sockets with true pressure-detection and subsequently pressure-relief characteristics. SmartSOCKET’s main objectives include: a) the integration of a computational model for computer-aided socket design and manufacturing, b) the development of optical fiber-based sensors to be embedded in the socket system for providing real-time strain/shear measurements, c) the embodiment and miniaturization of the fiber-sensors and interrogation units into the amputee socket and its calibration in laboratory environment, d) the realization of a signal processing algorithm for extracting the pressure/shear distribution map along the human-machine interface and for controlling the countershear actuator for pressure readjustment prior ulcer initiation, and e) the final socket validation through extensive laboratory and clinical trials. Given its interdisciplinary and highly ambitious nature, SmartSOCKET strongly relies on the knowledge transfer between its academic and industrial partners. SmartSOCKET will evolve upon the close collaboration between highly experienced academic personnel on cutting edge fiber technology and industrial people with knowledge of the true socket system requirements. SmartSOCKET is expected to lead to a promising technology transfer platform bringing the world of photonics confronted with true biomechanic applications whilst equipping the world of rehabilitation and knee prosthetics with a powerful fiber sensor toolkit.;1290785;1290785;FP7-PEOPLE-2009-IAPP;/MC-IAPP;S.S.F. Safe Smart Fabric Adaptable Surface Ltd;CY;"ETHNIKO KENTRO EREVNAS KAI TECHNOLOGIKIS ANAPTYXIS;VRIJE UNIVERSITEIT BRUSSEL;MEDCOM GESELLSCHAFT FUER MEDIZINISCHE BILDVERARBEITUNG MBH";"EL;BE;DE";"/SCI;/EDU;/ITT";1;0;0;1;0;0 98695;273635;ABIADA;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-IEF;FP7;From Minimally Autonomous Biological Individuals to Collectively Associated Autonomous Adaptive Agents;2011-04-01;2013-03-31;;'A great difficulty in theorizing and explaining living systems and their evolutionary patterns, is due to their individual-systemic and collective-evolutionary characteristics being so strongly and deeply intertwined. Biological individuals aggregate to collectively form more complex and diverse forms of biological organization in time, thus new forms of functionally and interactively diverse adaptive agents are produced. The problem is when one tries to specify the conditions and the terms in which such an organization and the respective evolutionary characteristics can be accounted for. Autonomy is considered as the fundamental concept to characterize and explain the underlying organization of several complex patterns of those evolutionary transitions. So far, only the concept of basic (minimal) autonomy is theoretically established, providing a naturalized explanation for the basic biological organization indicated by the metabolic functioning of living systems, at the level of the cell. Therefore, the project will examine: i) whether the concept of autonomy may account for more complex forms of collective associations of basically autonomous individuals, ii) whether general principles, that increase autonomy, and underlie evolutionary transitions in biological individuals, can be found, iii) whether forms of minimal cognition could appear through a process of creating new integrated forms of autonomy. The research will be carried out by a interdisciplinary analysis of diverse biological systems with diverse levels of complexity. It will provide conclusions for each objective on the background of complex-systems–based descriptions by constructing models with an emphasis on the characteristics and properties of the functional processes realized in each biological system under study. Overall, this project will build a coherent framework for a robust theoretical explanation and modeling of the properties governing and regulating more complex forms of autonomy.';160865,6;160865,6;FP7-PEOPLE-2010-IEF;/MC-IEF;UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA;ES;;;"/EMP;/EDU;/NET";1;0;0;1;0;0 103440;298743;WOUND IN EARTH;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IIF;FP7;Wound induced electrical signals in Arabidopsis thaliana;2012-05-01;2014-07-30;;'Electrical phenomena in plants were first documented in the 1800s, yet progress in this area has been slow. There is evidence that most plants produce electrical signals that travel long distances within the plant. This electrical activity is triggered by biotic and abiotic stimuli, supporting the notion that excitability is a robust biological trait in plants. Major objectives of this project are to characterize waveform parameters (e.g. duration, amplitude) as well as dynamic parameters (e.g. velocity) of electrical signals induced by wounding in Arabidopsis thaliana. To this end, we will develop a technique that uses aphid stylets severed from feeding aphids with a highly focused radio-frequency pulse. With this approach we will register single electrical signals that travel along the phloem, a major site of electrical activity. These intracellular recordings will be paired with surface recordings obtained simultaneously for the same signals. Wounds will be inflicted with a collimated laser beam, an approach that does not mechanically disturb the plant and is therefore suitable for electrophysiology, while allowing controlling location and size of the wound. Laser wounding induces an electrical signal similar in waveform and duration to that induced by mechanical wounding (crushing). Both wounding methods dramatically increase expression of JAZ10, a jasmonate response gene that is commonly used as a marker of the wound response. The wound-induced electrical signal will be also investigated in loss-of-function mutant plants that either do not produce the jasmonate response (aos mutant) or that do not respond to jasmonate (coi1-1 mutant). Whether aphid infestation remodels the wound-induced electrical signal will also be tested. This is an interdisciplinary project that brings together an expert in the plant's wound response and an expert in animal electrophysiology, to create new knowledge in a neglected area of Biology.';240455,07;240455,07;FP7-PEOPLE-2011-IIF;/MC-IIF;JULIUS-MAXIMILIANS-UNIVERSITAT WURZBURG;DE;UNIVERSITE DE LAUSANNE;CH;/SCI;1;0;0;1;0;0 100863;281356;MOPIT;ONG;FP7-IDEAS-ERC;ERC-SG-LS7;FP7;Molecular photoacoustic imaging of stem-cell driven tissue regeneration;2012-01-01;2016-12-31;;'I propose to develop a new generation of molecular photoacoustic imaging technologies and methods capable of detecting single deep tissue cells in preclinical studies of tissue regeneration. In order to achieve this goal, an interdisciplinary research programme involving physicists, engineers and life scientists is required to address the following objectives: 1) the development of novel photoacoustic imaging technology that provides high sensitivity and acquisition speed, 2) the development of the theoretical framework and experimental methods for quantitative imaging, 3) the development of novel genetically expressed reporters, and 4) the preclinical application in small animal models of tissue regeneration. This will result in a preclinical imaging modality has the potential to combine single cell sensitivity and microscale spatial resolution in deep (centimetre range) tissue regions with molecular, physiological, and anatomical imaging capabilities. The instrumentation and methodologies developed in this project will be applied to noninvasive, longitudinal, and quantitative studies of stem cell driven tissue regeneration, such as angiogenesis in bone fractures and muscle trauma. It will allow the detection and tracking of single stem cells and the probing of stem cell function. This will provide unprecedented opportunities for correlating cellular localization, migration, and function and with anatomical changes - knowledge that can be exploited to develop novel drugs and cell-based clinical therapies. Crucially, the technologies and methodologies developed in this project will be directly applicable to a wide range of other fields of the life sciences, such as cancer research and neurology.';1622736;1622736;ERC-2011-StG_20101109;/ERC-SG;TECHNISCHE UNIVERSITAET BERLIN;DE;CHARITE - UNIVERSITAETSMEDIZIN BERLIN;DE;"/BIO;/LIF";1;0;0;1;0;0 109007;330268;CME-REG;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IOF;FP7;Regulation of Clathrin-mediated Endocytosis by AP2 complexes;2013-07-01;2017-11-01;;'The plasma membrane represents the interface between cells and their neighborhood, mediating diverse processes such as cell–cell communication, cell–matrix interactions and uptake of nutrients. As a result, clathrin mediated endocytosis (CME) has a central role in maintaining cellular homeostasis and function and mis-regulation of endocytic traffic is linked to many human diseases. Yet, the mechanisms regulating CME remain poorly understood. We aim to define the role(s) of the adaptor protein-2 (AP2) in regulating CME. Using state-of-the-art molecular cell biology including siRNA knockdown and reconstitution through bicistronic retroviral mediated transfections, as well as genome editing we will generate stable cell lines expressing WT and functionally defined AP2 mutants. These will be analyzed by live cell total internal reflection fluorescence microscopy, in combination with sophisticated particle tracking algorithms and mathematical analyses to measure effects on discrete early stages of CME. We will determine how PI4,5P2, cargo, clathrin and endocytic accessory factor binding to AP2, as well as phosphorylation events trigger conformational changes in AP2 to regulate initial events in clathrin coated pit (CCP) assembly, stabilization of nascent CCPs and their maturation. Together these studies will test the hypothesis that allosteric conformational changes in AP2 play a central role in regulating early, critical events in CME. These interdisciplinary studies benefit from combining and transferring the most up-to-date experimental techniques and expertise in molecular cell biology, structural biology, microscopy, and mathematics. The collaboration between outgoing and European host ensures the expertise necessary to accomplish this complex goal. Most importantly it gives an opportunity to the applicant for training and career development in leading research institutions under the guidance of mentors who are world experts in their respective fields.';282561;282561;FP7-PEOPLE-2012-IOF;/MC-IOF;THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;UK;;;/LIF;1;0;0;1;0;0 109163;331219;SIGMA1R;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IEF;FP7;Structural Basis of Sigma-1 Receptor Ligand Interactions;2014-02-01;2016-02-14;;"The sigma-1 receptor is an endoplasmic reticulum (ER) integral membrane protein receptor is implicated in neurodegeneration, drug addiction, pain, amnesia, depression, Alzeimer’s disease, stroke, retinal neural degeneration, HIV infection, and cancer. In addition to its endogenous ligands, N,N- dimethyltryptamine (DMT) and the ER chaperone BIP, the sigma receptor binds a wide range of exogenous ligands and therapeutic compounds. Recent studies demonstrated potent antiapoptotic actions of Sigma-1, blocking neurodegeneration caused by beta-amyloid or ischemia. Other studies have shown sigma-1 antagonists capable of inhibiting tumor-cell proliferation. Despite numerous drug interactions, very little structural information about the sigma-1 receptor is available, partly because it does not share sequence homology with any other mammalian protein. Using a specially adapted E.coli expression system we can produce large amounts of pure, functionally active and isotopically labelled sigma receptor. We propose to solve the 3D structure of Sigma-1 by solution state NMR and characterise its ligand interactions at an atomic level and their regulation by cholesterol and ion binding. With a novel mammalian cell expression and isotopic labelling strategy and in-vivo assays we intend to further validate our work in-vivo with the aim of feeding our findings into the understanding of the Sigma-1 function in the cell and its modulation by drug binding. The implication of sigma-1 in many diseases makes it a potentially fruitful target for therapeutic intervention. Characterisation of sigma-1 receptor structure in the absence and presence of endogenous and exogenous ligands and cholesterol will shed light on its molecular action and will allow interdisciplinary projects for the development of more efficient therapies";231283,2;231283,2;FP7-PEOPLE-2012-IEF;/MC-IEF;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;UK;;;/SCI;1;0;0;1;0;0 102139;287034;ShockMeat;ONG;FP7-SME;SME-2011-1;FP7;Development of Shock Wave Technology for Packed Meat;2012-01-01;2014-04-30;http://www.shockmeat.eu;"In recent years the consumer demand has shifted towards convenient, easy to prepare meat products. In Europe mainly multiple use cattle varieties (milk and meat production) are raised, providing a small amount of tender meat pieces applicable for steak production, only. To produce beef and pork meat with sufficient quality for preparation of convenience food like steaks usually a post-mortal ripening is applied. Due to a time requirement of 14 to 21 days, meat maturation causes significant storage and energy costs. In pilot scale tests it was shown, that hydrodynamic shock wave treatment results in an accelerated meat maturation and allows tremendous improvements of meat quality and economic situation of SME meat producers. But up to now shock wave technology is not marketable. The lack of industry ready equipment, the knowledge of the process-product interactions as well as suitable packaging material limit an industrial application of the technique so far. In an interdisciplinary cooperation of SMEs and RTD-Performers ShockMeat will bridge the gap from research to industrial implementation of the technique by - development of an innovative industry ready shock wave equipment including meat handling, - identification of key processing parameters and elaboration of process-product interactions, - development of technology adapted packaging material, - deriving cost models and demonstration activities. With an annual turnover of approx. 202 million Euro meat industry is the most important sector of European food industry. By enhancing meat maturation product quality will be improved and processing costs reduced. ShockMeat will contribute to improve the competitiveness of SME in the area of meat processing, equipment manufacturing as well as packaging material. The consumer will benefit from meat products which are of higher quality (lower salt content, good texture, more tender, extended shelf life).";1742058,3;1311700;FP7-SME-2011;/BSG-SME;DEUTSCHES INSTITUT FUER LEBENSMITTELTECHNIK;DE;"OSTERREICHISCHES FORSCHUNGINSTITUT FUR CHEMIE UND TECHNIK;HVIDEBAEK SLAGTERI AS;SCHEYER VERPACKUNGSTECHNIK GMBH;TEKNOLOGISK INSTITUT;PROMATEC FOOD VENTURES BV;HIMMERLANDSKOD AS";"AT;DK;NL";/IND;1;0;0;1;0;0 97762;247586;BIMAUTOGEN;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IRSES;FP7;Collaboration for Research and Education in Automated Generation of Building Information Models;2011-09-01;2015-08-31;;The research objective of this proposal is to facilitate international collaboration and transfer of knowledge between international partners and to validate the hypothesis that the novel framework presented in Fig. 1 can be successfully used to generate parametric building models of buildings almost entirely automatically. The proposal’s most significant contributions will be, not only the automation of several mundane and repetitive processes with the addition of visual and spatial pattern recognition concepts in the modelling workflow, but also the exchange of knowledge and the building of transatlantic research collaborations on cutting-edge and high-impact scientific projects through the exchange of interdisciplinary staff among partner institutions and joint training of research teams on thematic areas of common research interest. The partners on this IRSES proposal have strong complementarities in their research interests and activities, and have already established synergies in their research endeavors that call for further strengthening. The international collaboration component of the proposed endeavor relies on the significant amount of interactivity between pairs of project participants and for the duration of the effort, aiming at the establishment of a long term, working relationship between researchers from different fields and countries, but with common research interests. These partnerships will bring together the senior personnel and their graduate and undergraduate students, and indirectly promote cross-pollination of their national and professional cultures. Furthermore, these partnerships will formalize frequent reciprocal visits of young researchers (graduate students and early career faculty members), and help establish formal exchange programs for undergraduate student researchers wishing to acquire some international experience while doing research and taking courses abroad.;286200;286200;FP7-PEOPLE-2009-IRSES;/MC-IRSES;THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;UK;"FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS;TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY;UNIVERSITY OF CYPRUS";"EL;IL;CY";"/SCI;/EDU;/ITT";1;0;0;1;0;0 107683;329795;MemoGram;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IEF;FP7;Grammar and memory: Evidence from agrammatic aphasia and probable Alzheimer's disease in German, Italian and Greek;2013-09-01;2015-08-31;;"'In Europe, there is an increasing number of people with neurological problems, such as probable Alzheimer’s disease (pAD) or aphasia, which often result in severe language and memory impairments. It has been argued that memory deficits contribute to the language problems brain-damaged populations face and, further, can predict these populations’ patterns of linguistic impairment. Interestingly, working (and perhaps semantic) memory deficits appear to differentially affect functional categories, resulting in a selective breakdown of grammar. However, there is no consensus as to the source of memory related processing difficulties for certain categories. The proposed study will investigate the relation between grammar and memory focusing on agrammatic aphasia (AA) and pAD in three morphologically rich European languages: German, Italian, and Greek. It will explore the ability of AA and pAD speakers to process functional categories which have different properties across and within these languages by means of on-line and off-line constrained tasks. The categories that will be tested are: Mood, Tense, Negation, subject-verb Agreement, gender Agreement and structural Case. Independent assessment of participants’ memory function will be made as well. The main goal of the project is to shed light on the precise relation between grammar and memory, detecting the factors that contribute to the processing load of a given category. The project will also have clinical implications: based on its 'basic research results', new treatment programmes for German-, Italian-, and Greek-speaking AA and pAD individuals will be developed. This project is highly interdisciplinary as it combines methods of theoretical linguistics, psycho-/neurolinguistics, cognitive and clinical (neuro)psychology, and speech and language therapy. It will contribute to the excellence of Europe in cognition and related disorders, as well as to a better treatment of populations suffering from AA or pAD.'";216952,8;216952,8;FP7-PEOPLE-2012-IEF;/MC-IEF;UNIVERSITAET POTSDAM;DE;;;/SCI;1;0;0;1;0;0 101036;289968;INDEX;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-ITN;FP7;"Indirect Excitons: Fundamental Physics and Applications";2011-11-01;2015-10-31;http://indexitn.coulomb.univ-montp2.fr/;"Indirect excitons are bosonic quasi-particles in semiconductors with unique properties: they have long lifetime and spin-relaxation time, can travel over large distances before recombination, can be cooled down to low temperatures and form a quantum gas, and can be controlled by voltage in-situ. Due to these properties, they form a model system both for the studies of fundamental properties of light and matter and for the development of conceptually new excitonic devices. Our consortium is composed of 9 strong academic groups in Europe and USA, supported by 4 industrial partners. It brings together the critical mass of the human resources, research expertise, experience, and facilities required to achieve a decisive breakthrough in the interdisciplinary field of indirect excitons, on the boundary of electronics, optics, photonics, and spintronics. We propose to explore the potential of indirect excitons (1) for the studies of fundamental physics of cold bosons in solid state materials, (2) for the development of novel principles for optoelectronic devices, and (3) for the training of a new generation of researchers. We propose a multidisciplinary training program aimed at formation of young researchers with solid background in physics of light-matter coupling and quantum effects in solid state, experts in excitonic systems able to design, process, and optimize the future excitonic devices for practical applications. The training in academic institutes will be combined with secondments to the major optoelectronic industries.";2973542,11;2973542,11;FP7-PEOPLE-2011-ITN;/MC-ITN;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FR;"THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;FUNDACIO INSTITUT DE CIENCIES FOTONIQUES;FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS;SCUOLA NORMALE SUPERIORE;CONSIGLIO NAZIONALE DELLE RICERCHE";"UK;ES;EL;IT";"/LIF;/SCI";1;0;0;1;0;0 96681;254270;OPTIMEYES;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IEF;FP7;Optimal Control of Eye Movements;2010-05-01;2012-04-30;;Optimal performance in a noisy and ambiguous environment requires that the human brain performs computations that are adapted to these conditions. Cognitive neuroscience has seen a major progress by applying Bayesian decision theory to explain human behaviour when humans were confronted with tasks where perception or behavioural outcomes were uncertain. In addition to these advancements, machine learning methods were successfully developed for handling noisy and incomplete datasets. In this research proposal we take an interdisciplinary approach, in which we design human motor control experiments and evaluate optimality of human performance by using machine learning techniques. Specifically, we will use eye-tracking experiments to explain how learning about visual stimuli supports the design of optimal eye movement strategies. Humans explore the visual environment by actively sampling the stimuli through performing a sequence of saccades. Limited time and resources require efficient eye movement planning and an optimal strategy necessitates the adaptation of the eye movement strategy both to the statistics of the stimuli and to the task performed. We develop a framework in which the contribution of top-down (task specific) and bottom-up information (low-level) to eye movement planning can be controlled and assessed. During the course of this proposal we intend to address three problems. First, we will explore how learning novel stimuli in the perceptual domain contributes to eye movement planning. Second, we will develop an optimal learner that relies on the same information that human participants have and assess whether human eye movements optimally exploit available information. Third, we will explore how bottom-up and top-down information is integrated and will use a probabilistic framework to analyze whether the optimal integration is compatible with human performance. This proposal strongly builds on a close collaboration between Prof. Wolpert and mysel;180603,2;180603,2;FP7-PEOPLE-2009-IEF;/MC-IEF;THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;UK;;;"/SCI;/EDU;/ITT";1;0;0;1;0;0 108552;329682;PSEUDOMODEL;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IEF;FP7;Integrative Modeling and Engineering of Pseudomonas putida for Green Chemistry;2013-06-01;2015-05-31;;"'The widespread use of fossil based fuels and plastics is a major cause of environmental pollution, and their production depends on limited non-renewable oil resources. The immense diversity of catalytic processes encoded in the genomes of sequenced organisms holds the promise of developing biotechnological systems for the efficient production of renewable energy sources and degradable materials via genetic engineering. However, the combinatorial possibilities for integrating enzyme-coding genes from different organisms into a microbial host cannot be explored systematically by classical approaches, which rely on the manual review of functional gene annotations. We propose to integrate a novel computational method for predicting combinations of genes facilitating efficient product yield with experimental approaches for genetic engineering. The method takes into account virtually all combinations of genes from sequenced organisms while avoiding the combinatorial explosion of their enumeration. We iteratively validate and refine the method by application to the genetic engineering of the well-characterised P. putida KT2440 for the production of polyhydroxyalkanoates, important precursors for biodegradable materials. Next, we apply the refined method to the solvent tolerant P. putida DOT-T1E for the production of n-Butanol, a promising next generation biofuel due to its high energy density, safe handling, and the possibility of direct use in gasoline motors. The interdisciplinary integration of theoretical and experimental research within the project is a promising approach for addressing the modern challenges in developing new biotechnological production systems. The project will lead to the discovery of engineered strains for the efficient production of biofuel and degradable materials, enabling novel industrial processes in green chemistry with the potential of alleviating environmental pollution and promoting economic independence from oil production.'";173370,6;173370,6;FP7-PEOPLE-2012-IEF;/MC-IEF;AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS;ES;;;/SCI;1;0;0;1;0;0 108089;328502;PALEOHUNT;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IEF;FP7;The reconstruction of hunting techniques as an instrument to understand the diffusion of populations and ideas in European Palaeolithic;2013-09-01;2015-08-31;;"'This project aims to reconstruct changes in hunting strategies during the European Upper Palaeolithic through the analysis of stone tools and bone points in order to understand the mode and timing of the spread of new techniques and ideas and whether they relate to physical movement of people or assimilation of ideas. A new multidisciplinary and methodological approach involving the techno-functional analysis of projectile points, residue analysis and a thorough ethnographic study, will be used to compare data from different archaeological contexts. The main phase of the project will involve the comparative analysis of hunting equipment from the principal Moravian Gravettian sites (Doln? Vestonice and Pavlov, Czech Republic) with that from the Italian site of Grotta Paglicci to determine whether tools share morphological and functional characteristics and how they are linked to hunting in different natural environments. The project will link to the interdisciplinary 'Moravian Gate' project currently hosted by the McDonald Institute for Archaeological Research, University of Cambridge. This aims to understand human adaptation to climate change and natural resources during the Gravettian (30,000 – 20,000 BP) in a crucial, densely populated area of Central Europe, Moravia. The Paleohunt project will take this a step further and extend it to the Epigravettian and the mediterranean zone.'";309235,2;309235,2;FP7-PEOPLE-2012-IEF;/MC-IEF;THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;UK;;;/SCI;1;0;0;1;0;0 103414;300572;Hilbert compression;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IEF;FP7;Generalized Hilbert space compression and coarse geometry of data sets;2012-10-01;2014-09-30;;"'Metric spaces, such as graphs, occur everywhere in mathematics and are used to model real life situations: in computer science e.g., they are used to model computer networks and in sociology, graphs are used to model interhuman relations. In order to study metric spaces, one can embed them into an object which one understands quite well. The information that we know on the latter object may then provide useful information on the embedded metric space. A Hilbert space is a well understood mathematical object which can be studied by algebraic techniques (it is a vector space, with an inner product), by analytic techniques (least square methods) and by many more tools. Around the 1990s, Gromov introduced the notion of metric spaces that `embed uniformly' into a Hilbert space. This relatively weak condition turned out to be connected with some major conjectures: it implies the coarse Baum-Connes and Novikov conjecture in the case of finitely generated groups. The equivariant version of uniform embeddability is Haagerup's property, a property with clear connections to the Baum-Connes conjecture and a subject of intense study. Guentner and Kaminker define the (equivariant) Hilbert space compression of a f.g. group as a number between 0 and 1 which quantifies how 'well' the group embeds uniformly into a Hilbert space (is Haagerup respectively). Moreover, they showed that if the value of the (equivariant) compression is strictly greater than 1/2, then the group has Yu's property (A) (is amenable respectively). This shows that the compression notions contain important information on the group, making them very interesting to study. This Marie Curie project fits in this setting. We intend to study compression through new techniques such as persistent cohomology, determine the relations between compression and related properties such as Property A and amenability and apply compression in an interdisciplinary setting by using it to study data sets.'";200371,8;200371,8;FP7-PEOPLE-2011-IEF;/MC-IEF;UNIVERSITY OF SOUTHAMPTON;UK;;;/SCI;1;0;0;1;0;0 109215;607517;ARIADME;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-ITN;FP7;Analytical Research In ADME profiling (ARIADME);2013-10-01;2017-09-30;;The integration of absorption, distribution, metabolism and excretion (ADME) profiling into early drug discovery has been put forward as a strategy for reducing drug candidate attrition. Europe is challenged to develop novel ADME screening methodologies with increased efficiency and predictive power to profile the multitude of lead compounds currently being generated. The principal objective of this programme is to train a new generation of ADME scientists, equipped to tackle the challenge. To this end, a structured, interdisciplinary training programme is set up. The scientific aim of the programme is to improve and expand the current ADME profiling armamentarium by introducing 1) innovative in vitro and in vivo ADME tools 2) novel analytical methodologies and 3) new approaches for ADME data handling and computational modelling. State-of-the-art technologies are coupled with novel methodologies. All research projects rely to a great extent on analytical techniques. In addition to training-through-research, the programme provides a multi-stage training on a network-wide level as well as specialised local activities. The programme will enrol 13 early-stage researchers in a training consortium consisting of 4 academic and 2 industrial partners with worldwide recognised expertise. The trainees will develop in-depth insight and hands-on experience in ADME profiling, as well as scientific breadth and transferable skills. The high degree of intersectoral collaboration and cross-fertilisation fills many of the gaps in current educational paradigms and widens the career perspectives of the trainees in different institutional sectors including education, government and industry. The programme will organise open dissemination events to facilitate the transfer of newly generated knowledge to the broader EU community. The combined goal of the training efforts and innovative research is to lead Europe to the frontline in ADME profiling and secure a leadership position therein.;3668742;3668742;FP7-PEOPLE-2013-ITN;/MC-ITN;KATHOLIEKE UNIVERSITEIT LEUVEN;BE;"STICHTING VU;Unilever research and development Vlaardingen BV;KOBENHAVNS UNIVERSITET;UPPSALA UNIVERSITET;JANSSEN PHARMACEUTICA NV";"NL;DK;SE;BE";/LIF;1;0;0;1;0;0 109699;611272;GROWTHCOM;ONG;FP7-ICT;ICT-2013.5.4;FP7;GROWTH AND INNOVATION POLICY-MODELLING: APPLYING NEXT GENERATION TOOLS, DATA, AND ECONOMIC COMPLEXITY IDEAS;2013-10-01;2016-09-30;;In the wake of the financial crisis one of the major challenges faced by policymakers in Europe and around the world is re-kindling economic growth and innovation. Recent research portrays economic growth as a process of evolution of ecosystems of technologies and industrial capabilities. This research has also shown a strong relationship between the development of the complexity of economies in a globalized market and overall output growth. ICT based tools, in particular complex systems analysis, simulation, systems science methods, and big data capabilities offer policymakers new opportunities to empirically map technology and capability ecosystems of countries and industrial sectors, analyse their structure, understand their dynamics, measure economic complexity, and design policy interventions more likely to have positive impacts on growth over time. This project proposes to apply ICT tools in this way to yield insights on the industrial competitiveness and fragility of countries, the evolution of technologies and capabilities, the network of products, the adaptability of companies, and the ecology of E-commerce. In particular, E-commerce provides an important example of the active involvement of citizen in terms of their feedbacks on products and companies. The project will be a European and global collaboration amongst a network of researchers highly experienced in these topics. The teams involved represent an interdisciplinary consortium in which various research lines will be integrated in a network of collaborative effort to address challenging problems for a new vision of a data driven fundamental economics in a strongly connected, globalised world. The results of the project will provide a novel basis for economic forecasting and risk analysis for countries, companies and technological sectors, and they will also provide a new perspective for growth and innovation policymaking.;2033605;1563317;FP7-ICT-2013-10;/CP;CONSIGLIO NAZIONALE DELLE RICERCHE;IT;"LONDON CENTRE FOR MATHEMATICAL SCIENCES LBG;Hangzhou Normal University;UNIVERSITE DE FRIBOURG";"UK;CN;CH";/INF;1;0;0;1;0;0 103506;298303;HUMVIRET;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IEF;FP7;"""Hume’s Ethics of Virtue: Sentiments, Character, and Reflection""";2012-10-01;2014-09-30;;'This research project aims at presenting the moral philosophy of David Hume as an original Ethics of Virtue, in line with the Virtue Ethics tradition, to be presented as a promising theoretical alternative within present-day ethical debate. Hume’s ethical thought has been an ongoing source of inspiration for many, but it has been interpreted in different, often conflicting ways. This research project will read it as the clearest and most convincing form of sentimentalism, i.e. the stance whereby the sphere of ethics can be completely explained and justified by a methodical enquiry into the sentiments and passions of human nature, and not by making reference to reason, or to an external moral reality. Through an interdisciplinary enquiry which combines together an extensive study of Hume texts, a careful examination of the secondary literature by Hume scholars, and a strict discussion of the latest advancements in contemporary moral philosophy, Hume’s sentimentalism will be presented as an account of morality in terms of the capacity of passionally defined agents to put their moral sentiments under reflective scrutiny. An investigation of Hume’s ethical solutions in the light of sentimentalism, read in a reflective light, is an interesting theoretical platform from which to deepen our knowledge of Hume, and address in a brand-new and systematic way some central themes in contemporary moral philosophy regarding the nature of normativity, its relation to people’s motivation, and the structure of people’s characters considered as virtuous agents.';270145,8;270145,8;FP7-PEOPLE-2011-IEF;/MC-IEF;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;UK;;;/SCI;1;0;0;1;0;0 102965;298865;RESEARCH NETWORKS;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IOF;FP7;"Research Networks for Educational Reform A ‘School-University Research Network’ Perspective on Linking Teacher Education, Knowledge and School Development";2013-03-01;2016-02-29;;"School-university research networks aim for closer integration of research-based knowledge and practice by means of teacher research, which can provide sustainable educational development in both schools and universities. Recently, scholars have suggested that master’s programs for in-service teachers may be a promising avenue in developing such research networks for educational reform. This worldwide innovative approach can reveal promising directions for linking teacher education, knowledge and school development, which may ultimately contribute to improving education and enhancing student achievement. As such, it contributes to the European Union goal of improving higher education and education in general (Europe 2020 – Flagship initiative Youth on the Move). Given the recent proliferation of a ‘school-university research network’ perspective on in-service teacher education there remains limited empirical work about this type of research networks. This study aims to address this pressing research gap and the need for finding new ways of improving educational systems. Two innovative and promising contexts in the U.S. and U.K will be explored. Theory and methods from the interdisciplinary field of social networks and the fields of teacher learning and education studies will be combined. An original combination of quantitative and qualitative methods will be used as well as longitudinal network modeling to examine networks and processes over time. The project aims to provide the fellow with training and career development support at two world class universities to become a mature and excellent scholar in the European Research Area (ERA). The outgoing (University of California,U.S.) and return host (University of Cambridge,U.K.) have robust infrastructures to manage/implement the project and mentors are renowned scholars in the field of educational networks. Outreach activities and an international advisory board will secure application of experiences/results in ERA";283568,1;283568,1;FP7-PEOPLE-2011-IOF;/MC-IOF;THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;UK;;;/SCI;1;0;0;1;0;0 110884;335086;LattAC;ONG;FP7-IDEAS-ERC;ERC-SG-PE6;FP7;Lattices: algorithms and cryptography;2014-01-01;2018-12-31;;"Contemporary cryptography, with security relying on the factorisation and discrete logarithm problems, is ill-prepared for the future: It will collapse with the rise of quantum computers, its costly algorithms require growing resources, and it is utterly ill-fitted for the fast-developing trend of externalising computations to the cloud. The emerging field of *lattice-based cryptography* (LBC) addresses these concerns: it resists would-be quantum computers, trades memory for drastic run-time savings, and enables computations on encrypted data, leading to the prospect of a privacy-preserving cloud economy. LBC could supersede contemporary cryptography within a decade. A major goal of this project is to enable this technology switch. I will strengthen the security foundations, improve its performance, and extend the range of its functionalities. A lattice is the set of integer linear combinations of linearly independent real vectors, called lattice basis. The core computational problem on lattices is the Shortest Vector Problem (SVP): Given a basis, find a shortest non-zero point in the spanned lattice. The hardness of SVP is the security foundation of LBC. In fact, SVP and its variants arise in a great variety of areas, including computer algebra, communications (coding and cryptography), computer arithmetic and algorithmic number theory, further motivating the study of lattice algorithms. In the matter of *algorithm design*, the community is quickly nearing the limits of the classical paradigms. The usual approach, lattice reduction, consists in representing a lattice by a basis and steadily improving its quality. I will assess the full potential of this framework and, in the longer term, develop alternative approaches to go beyond the current limitations. This project aims at studying all computational aspects of lattices, with cryptography as the driving motive. The strength of LattAC lies in its theory-to-practice and interdisciplinary methodological approach";1414401,6;1414401,6;ERC-2013-StG;/ERC-SG;ECOLE NORMALE SUPERIEURE DE LYON;FR;;;"/PSE;/IPS";1;0;0;1;0;0 111063;335692;BEYOND;ONG;FP7-IDEAS-ERC;ERC-AG-LS4;FP7;METABOLIC BASIS OF NEURODEGENERATIVE DISEASE;2014-02-01;2019-01-31;;Alzheimer disease (AD) is the most common form of age-related dementia affecting millions of patients worldwide. Disturbingly, disorders of lipid and glucose metabolism emerge as major risk factors for onset and progression of neurodegeneration in the human population. Thus, an increasing life expectance combined with an observable rise in metabolic disturbances is expected to turn AD into one of the most serious health problems for future generations. Still, the molecular mechanisms whereby dysregulation of glucose and lipid homeostasis elicits noxious insults to the brain remain poorly understood. We characterized a novel class of intracellular sorting receptors, termed VPS10P domain receptors with dual roles in regulation of neuronal viability and function, but also in modulation of glucose and lipid homeostasis. Our proposal aims at elucidating an important yet poorly understood link between metabolism and neurodegeneration that converges on these receptors. Our approach is unique and novel in several ways. Thematically, our studies focus on a novel class of receptors previously not considered. Based on the receptors’ ability to act as sorting proteins, we propose faulty protein trafficking as a major unifying concept underlying neurodegenerative and metabolic disorders. Conceptually, our approach relies on the interdisciplinary effort of neuroscientists and metabolism researchers working jointly on pathophysiological pathways converging on these receptors. Through this effort, we are confident to gain important insights into the crosstalk between brain and peripheral tissues, and to elucidate pathways common to metabolic disturbances and dementia, two prevailing degenerative disorders inflicting our societies.;2415229;2415229;ERC-2013-ADG;/ERC-AG;MAX-DELBRUCK-CENTRUM FUR MOLEKULAREMEDIZIN;DE;;;"/LIF;/MED;/MBI";1;0;0;1;0;0 87399;203428;NMU-LIPIDS;ONG;FP7-IDEAS-ERC;ERC-SG-PE6;FP7;Biomimetic Lipid Structures on Nano- and Microfluidic Platforms;2008-07-01;2014-06-30;;The projects aim at the formation, manipulation, and analysis of three-dimensional lipid membrane structures on micro- and nano-structured platforms. The goal is to develop a novel methodology to design and create simple artificial cells and cell organelles, bio-hybrid cells, and bio-mimicking membrane networks, which could be an entirely novel tool for cell analysis, and promises fascinating prospects for cell manipulation, biotechnology, pharmacy and material sciences. The basis of the projects is formed by an unconventional concept that involves two current cutting-edge fabrication technologies, i.e. the so-called top-down and bottom-up approaches. The combination of the two approaches, with respect to both engineering methods and biological applications, opens the door to overcome current limitations in the creation of complex soft matter objects in micro- and nanometre dimension. The key method is a recently developed micro-extrusion process. It relies, on the one hand, on the ability of the lipid molecules to self-assemble (“bottom-up”). On the other hand, photolithography processes (“top-down”) are utilized to fabricate microchips, in which shape transformation, handling and analysis of the lipid structures are performed. The proposed engineering process will enable, for the first time, to precisely design composition, size and morphology of complex membrane structures. It will provide the requirements to design an artificial cell of reasonable complexity (“bottom-up”). One main emphasis is the creation of unique bio-hybrid systems, in which artificial membrane structures are connected to living cells, or in which natural membranes of cells are integrated within artificial systems (“top-down”). This highly interdisciplinary study will further include fundamental studies on membrane properties, engineering aspects to generate novel soft-matter devices, and the development of analytical methods and lipid sensors based on micro- and nanostructured chips.;1941000;1941000;ERC-2007-StG;/ERC-SG;EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH;CH;LEIBNIZ-INSTITUT FUR ANALYTISCHE WISSENSCHAFTEN-ISAS-EV;DE;"/PSE;/IPS";1;0;0;1;0;0 109592;608593;EUROSUNMED;ONG;FP7-ENERGY;ENERGY.2013.2.9.1;FP7;EURO-MEDITERRANEAN COOPERATION ON RESEARCH & TRAINING IN SUN BASED RENEWABLE ENERGIES;2013-09-01;2017-08-31;http://www.eurosunmed.eu;The scientific targets of the EUROSUNMED project are the development of new technologies in three energy field areas, namely photovoltaics (PV), concentrated solar power (CSP) and grid integration (GI), in strong collaboration with research institutes, universities and SMEs from Europe in the north side of the Mediterranean sea and from Morocco and Egypt from the south of the sea. The focus in PV will be on thin film (Si, CZTS) based solar cells and modules while the goal in CSP field is to design and test new heliostats as well as novel solutions for energy storage compatible with these technologies. The project aims at producing components that will be tested under specific conditions of MPC (hot climate, absence of water, etc.). Such investigations are complemented with studies on grid integration of energy sources from PV and CSP in Morocco and Egypt context. Additionally, the consortium envisages to train PhD students and Post-Docs in these interdisciplinary fields in a close and fruitful collaboration between academic institutions and industry from EU and MPCs. The consortium is well placed around leading academic groups in materials science and engineering devices and equipments for the development of PV and CSP, and also in the promotion of the renewable energies in general. Moreover, technology transfer and research infrastructure development in the targeted areas will be provided. Disseminating the results of the projects will be done through the organization of summer schools, workshops and conferences towards large public from universities, engineering schools and stakeholders involved in the three selected energy areas and beyond. Another outreach of the project will be the proposal for a roadmap on the technological aspects (research, industry, implementation) of the PV, CSP and grid area as well as on the best practice for the continuation of strong collaboration between the EU and MPCS partners and beyond for for mutual interest and benefits.;6301821,3;5261726,15;FP7-ENERGY-2013-1;/CP-SICA;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FR;"SINTEF ENERGI AS;HELWAN UNIVERSITY;TURBODEN SRL;CENTRE NATIONAL POUR LA RECHERCHE SCIENTIFIQUE ET TECHNIQUE;FUNDACION TEKNIKER;UNIVERSITE MOHAMMED V DE RABAT;STIFTELSEN SINTEF;EUROPEAN MATERIALS RESEARCH SOCIETY;MOROCCAN AGENCY FOR SOLAR ENERGY SA;NILE VALLEY ENGINEERING COMPANY PARTNERSHIP;EUREC EESV;ALEXANDRIA UNIVERSITY;MOROCCAN FOUNDATION FOR ADVANCED SCIENCE INNOVATION AND RESEARCHFONDATION MASCIR;UNIVERSITE AL AKHAWAYN D'IFRANE;FUNDACION CENER-CIEMAT;University Mohammed V-Agdal;CENTRE NATIONAL DE L'ENERGIE DES SCIENCES ET TECHNIQUES NUCLEAIRES";"NO;EG;IT;MA;ES;FR;BE";"/ESV;/EST";1;0;0;1;0;0 88951;215009;RED CAT;ONG;FP7-PEOPLE;PEOPLE-2007-1-1-ITN;FP7;Natural Products and related Redox Catalysts: Basic Research and Applications in Medicine and Agriculture;2008-12-01;2012-11-30;;"Intracellular redox processes are pivotal for cell survival and proliferation. Redox active natural products, enzymes and their mimics may therefore be considered as regulators of various cellular processes which may, for instance, control inflammatory processes, cancer formation and proliferation, but also bacterial, fungal and microbial growth. It is now apparent that redox control exerted by such natural and synthetic products may be used for prevention and therapy in Medicine and for the development of ‘green’ pesticides in Agriculture. This training network will study chemical, biochemical and biological aspects of the modulation of cellular redox balances by selected natural agents and their mimics. It relies on expertise of 10 full and 7 associated partners (1 SME) in a range of scientific disciplines, including synthetic, analytical, biological and pharmaceutical chemistry, biochemistry, cell biology, microbiology, cancer research and agricultural research. The network will address 4 36-month work packages (WP): A WP on natural antioxidants, inflammation and cancer; a WP studying intracellular redox control and signalling events triggered by external redox agents; a WP on green antibiotics and pesticides from plants and fungi; a WP on redox catalysts as agents selective against cancer and inflammatory cells. The network will provide interdisciplinary training for 4 experienced and 10 early stage researchers, all of which will acquire expertise in 3 or more of scientific disciplines. Each researcher will develop a training portfolio when joining the network. All early stage researchers are expected to obtain international recognised PhD degrees. In addition to intensive scientific training at various host institutes, there will be a framework programme offering training in science related matters and soft skills, such as logical and ethical aspects of research, IP, patenting and commercialisation, communication skills and cultural and gender issues.";2785650;2785650;FP7-PEOPLE-2007-1-1-ITN;/MC-ITN;UNIVERSITAT DES SAARLANDES;DE;"UNIVERSITE DE LORRAINE;THE UNIVERSITY OF EXETER;ECOSPRAY LIMITED;RECHERCHES SCIENTIFIQUES LUXEMBOURG ASBL;RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN;DEUTSCHES KREBSFORSCHUNGSZENTRUM HEIDELBERG;URSAPHARM Arzneimittel GmbH;UNIVERSIDADE DE AVEIRO;UNIVERSITE PARIS DESCARTES";"FR;UK;LU;DE;PT";"/EMP;/SOC;/EDU";1;0;0;1;0;0 111001;340929;SWITCH2STICK;ONG;FP7-IDEAS-ERC;ERC-AG-PE8;FP7;Engineering of biomimetic surfaces: Switchable micropatterns for controlled adhesion and touch;2014-02-01;2019-01-31;;'Nature has, in the course of evolution, found many fascinating solutions to “engineering problems”. The proposed work aims at three-dimensional (3D) surface structures inspired by insects, spiders and geckoes. Based on the PI’s earlier work on passive structures, the new challenge addressed by this interdisciplinary project is to design and investigate active, switchable 3D micropatterns, whose adhesion and touch can be tuned at will and modified on demand. The resulting features will bend or tilt in response to external stimuli (especially temperature, electric field and stress) and thereby create a responsive surface structure. Theoretical modelling and simulation of the relevant mechanics will be a major effort to establish “structure-property relationships” for switchable patterned surfaces, to guide the choice of structure parameters and to establish new multifunctional design rules for targeted applications. Emphasis will be placed on the novel aspect of interaction with soft, compliant objects, with a view to creating future opportunities for interaction with soft matter and skin. Talented junior scientists – with both experimental and theoretical background - will be heavily involved as an opportunity to promote their career opportunities in this modern field of materials research. A final objective will be the exploration of the transferability of patterning techniques to larger-scale areas. Overall, such switchable micropatterns will likely open up revolutionary new possibilities in various technologies: robotic grippers with careful, benign “touch” of delicate objects, medical adhesives that become sticky on reaching body temperature, and active devices that can respond and send signals to touching fingers. The successful project will thus lay the scientific foundations for innovative devices and solutions that will improve our competitiveness and the living conditions of an ageing society.';2482800;2482800;ERC-2013-ADG;/ERC-AG;LEIBNIZ-INSTITUT FUER NEUE MATERIALIEN GEMEINNUETZIGE GMBH;DE;;;"/PSE;/MAT;/IND;/CON";1;0;0;1;0;0 109126;609078;EASY-IMP;ONG;FP7-NMP;FoF.NMP.2013-5;FP7;Collaborative Development of Intelligent Wearable Meta-Products in the Cloud;2013-09-01;2016-08-31;http://www.easy-imp.eu;"A (Meta-) product is now a customer driven customisable entity that integrates sensory/computing units, which are in turn connected to the cloud, leading to a paradigm shift from mass production to intelligent, over-the-web configurable products. Product design and production is however becoming highly complex and requires interdisciplinary expertise. The goal of EASY is to develop new methodologies, tools and ready-to-use components for designing and producing intelligent wearable products as Meta-Products. We propose a Cloud Computing enabled framework for the Collaborative Design and Development of Personalised Products/Services, combining embedded sensors and mobile devices with facilities for joint open development of enabling downloadable applications. The Meta-Products consist of intelligent wearables (clothing, footwear, accessories) equipped with embedded networks of sensors. Sensorial data will be communicated to smart phones via Bluetooth or Wifi. The required functionality will be configured by the end-users; the design, selection of components, sourcing of materials and sensors, virtual prototyping, as well as production planning and services integration is a collaborative process of all involved companies, designers, sensor producers, software developers and application experts. This infrastructure will enable all interested 3rd parties to offer new services to smart phone and EASY wearable users, resulting to an open platform of literally infinite applications in many target market. The EASY approach will be validated in three different industrial scenarios, i.e. rehabilitation, sport and games. The EASY-Consortium integrates competences on production methodology, system design and modeling, product lifecycle management, simulation and virtual reality, intelligent sensors, mobile-cloud systems, intelligent cloth design and production.";6248965,4;4399295;FP7-2013-NMP-ICT-FOF(RTD);/CP-IP;DEUTSCHES FORSCHUNGSZENTRUM FUR KUNSTLICHE INTELLIGENZ GMBH;DE;"ATHENS TECHNOLOGY CENTER ANONYMI BIOMICHANIKI EMPORIKI KAI TECHNIKI ETAIREIA EFARMOGON YPSILIS TECHNOLOGIAS;UNIVERSITE LUMIERE LYON 2;SMART SOLUTIONS TECHNOLOGIES S.L;FEDERATION OF THE EUROPEAN SPORTING GOODS INDUSTRY;HYPERCLIQ IKE;ATOS SPAIN SA;INSTITUTO DE BIOMECANICA DE VALENCIA;INTERACTIVE WEAR AG;UNIVERZITETNI REHABILITACIJSKI INSTITUT REPUBLIKE SLOVENIJE-SOCA;TIMOCCO LTD;SYLVIA LAWRY CENTRE FOR MULTIPLE SCLEROSIS RESEARCH E.V.";"EL;FR;ES;BE;DE;SI;IL";/SCI;1;0;0;1;0;0 97346;246005;COFIT;ONG;FP7-PEOPLE;FP7-PEOPLE-COFUND-2008;FP7;COFIT (COFUND International Trade);2011-01-31;2016-01-30;;"The World Trade Institute (WTI) and its Swiss National Centre of Competence in Research – International Trade Regulation (NCCR) propose to establish a COFUND International Trade Fellowship Programme (COFIT) offering incoming mobility and reintegration schemes to nationals from eligible countries. The WTI is an interdisciplinary centre of advanced studies and research in international trade regulation and policy, based in Bern, Switzerland. Its world-class teaching and research programmes foster interaction between academics, policy makers and trade professionals. Since 2005, the WTI has integrated the NCCR, a large-scale multidisciplinary research centre of law, economics, and political science, funded by the Swiss National Science Foundation (SNSF). The establishment of a broad network of partner universities and research centres across Switzerland and the EU, and the scientific input and review by a pool of international scholars and experts, has made it possible for the NCCR to establish itself as a leading centre in the field of international trade policy and regulation, both in Europe and abroad. For its second phase, from September 2009 to August 2012, the SNSF has pledged to endow the NCCR with a research fund of CHF 9.38 million (€6.25 million), which will add to the WTI's continuing provision of self-funded research infrastructure and administration services in support of the NCCR and its activities. The WTI/NCCR now sees scope to enhance its critical mass and impact potential through a substantial increase in the number of fellowship programmes it is able offer. We believe that this is best achieved by pursuing a symbiotic relationship between the Swiss NCCR and the EU COFUND financing schemes, whereby the latter would be devoted entirely to the financing of trans-national fellowships, mainly for experienced EU researchers.";585949;234379,6;FP7-PEOPLE-COFUND-2008;/MC-COFUND;UNIVERSITAET BERN;CH;;;"/ECO;/REG;/INF";1;0;0;1;0;0 105412;317110;ESCODNA;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-ITN;FP7;European School of DNA Nanotechnology;2013-02-01;2017-01-31;;"DNA Nanotechnology is an emerging interdisciplinary area that will underpin the development of future nanoscience-based technologies for areas such as medicine, diagnostic tools, optics and electronics. DNA nanotechnology is based on the unique self-assembly properties of DNA which allow the rational design and synthesis of complex nanoscale structures with predictable form and function. Many other materials can be integrated in such DNA structures to create highly functional nanodevices. The Marie Curie ITN EScoDNA will establish a sustainable European School of DNA Nanotechnology. By providing high quality training to young scientists, EScoDNA will improve their career prospects in both public and private sectors; it will also strengthen the competitive position of European research and industry in this promising strategic field. A network of leading European researchers, two SMEs and a major commercial research institute will work together to foster the development of a new generation of scientists with the skills required to meet future challenges in DNA nanotechnology, from fundamental science to novel applications. The training program will involve collaborative research projects, including international secondments and exchange of data through a web-based Lab-Wiki Journal, and through summer schools and workshops. The industrial partners will be integrated in the training programme, and the two SMEs will coordinate training related to the commercial exploitation of new technologies, management and entrepreneurial skills. They will also take a lead in managing the protection and commercialization of new technologies arising from research with the ITN. The programme is designed to create a pool of highly qualified researchers prepared for a wide range of careers in bionanotechnology and nanofabrication and, especially, capable of contributing to the development of a strong European centre for the scientific and commercial development of DNA nanotechnology.";4070204,13;4070204,13;FP7-PEOPLE-2012-ITN;/MC-ITN;AARHUS UNIVERSITET;DK;"LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN;TECHNISCHE UNIVERSITAET MUENCHEN;BASECLICK GMBH;VIPERGEN;KAROLINSKA INSTITUTET;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD";"DE;DK;SE;UK";/LIF;1;0;0;1;0;0 108729;331496;ER and Infection;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IIF;FP7;ER Function In Virus Infection;2013-07-29;2015-11-24;;A major challenge in combating significant human pathogens is the inherent variation of viruses that can evolve to evade the host immune response and antiviral treatment strategies. Our research proposes an interdisciplinary approach to identify novel antiviral targets by interrogating the host cell biology of infection by influenza A virus (IAV), human immunodeficiency virus (HIV) and hepatitis C virus (HCV) using high-throughput RNA interference (RNAi) technologies. More specifically, we propose to understand the dependency of these enveloped viruses on the host endoplasmic reticulum (ER) machinery for virus replication and propagation and how this increased virus burden activates host-ER stress, including the unfolded protein response (UPR). The UPR is implicated in inflammatory signaling and we will further investigate whether these viruses can modulate host immune responses via this pathway. In summary, we have proposed a hypothesis-driven RNAi screen to generate an overview of common host-cell factors exploited by diverse viruses during infection as well as extensive biochemical and functional validation of any sites of conserved virus-protein interactions. Therefore, this work aims to identify novel candidates for further translational research and development as improved, broad-spectrum antiviral treatments to combat infection and associated pathogenesis.;183469,8;183469,8;FP7-PEOPLE-2012-IIF;/MC-IIF;UNIVERSITEIT UTRECHT;NL;;;/SCI;1;0;0;1;0;0 105458;316748;LanPercept;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-ITN;FP7;Language and Perception;2013-01-01;2016-12-31;;'This network provides a unique approach to understanding the interaction between two central cognitive systems: language and perception. Traditionally these systems have been studied independently, with training provided from a single discipline perspective. This training network offers an interdisciplinary approach to the examination of the bidirectional relationships between language and perception for the first time, bridging the translational gap between basic and applied research, both in clinical settings and in industry. The workpackages in the training program form three interconnected clusters: (1) 'Language-perception interactions in healthy participants - basic research' investigates theories of language and perception from complementary perspectives in order to break new ground in understanding language-perception interactions. (2) 'Language-perception interactions in atypical populations – applied research' transports state-of-the-art methods of language-perception to atypical populations in order to identify underlying mechanisms for different kinds of atypical behaviours. (3) 'Advanced technologies for language and perception' research bridges basic research and its applications in the development of new behavioural and neurophysiological techniques to identify the interaction between language and perception among typical (adults and children) and atypical populations. Industrial partners within the ITN will work across all three clusters, offering project-specific collaboration with ER and ERS trainees, secondment placements, entrepreneurial training at schools and courses, as well as supervision and industrial guidance through supervisory board and educational committee participation. This ITN will produce a new generation of integrative language and perception scientists with the technological, theoretical, and entrepreneurial skills necessary to make breakthroughs in the understanding of language-perception interactions and associated applications';4152363,18;4152363,18;FP7-PEOPLE-2012-ITN;/MC-ITN;NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU;NO;"UNIVERSITY OF EAST ANGLIA;TOBII TECHNOLOGY;FUNDACION INSTITUTO VALENCIANO DE NEUROREHABILITACION;SYDDANSK UNIVERSITET;ERASMUS UNIVERSITEIT ROTTERDAM;UNIVERSITAET BIELEFELD;ASTON UNIVERSITY;UNIVERSIDAD DE SEVILLA;UNIVERSITAT DES SAARLANDES";"UK;SE;ES;DK;NL;DE";/LIF;1;0;0;1;0;0 110238;336564;VR3PP;ONG;FP7-IDEAS-ERC;ERC-SG-SH5;FP7;Visual Representations of the Third Plague Pandemic;2013-10-01;2018-09-30;;"The project will investigate how the emergence of photography as a new technology played a pivotal role in the wider acceptance of bacteriological explanations of pestilence in the course of the third plague pandemic (1855-1959) and how it transformed public consciousness of infectious disease, hygiene, and the role of international cooperation in the protection of public health, by establishing plague as a paradigmatic agent of death and disorder in the modern age, whilst, at the same time, opening up an era where the meaning of health emergencies is actively and publically negotiated on a cross-cultural global basis. The project will collect and analyse for the first time all visual documents of the third plague pandemic, which broke out in 1855 in Southwest China and raged across the globe until 1959, causing the death of approximately 12 million people. The project’s aim is to engage in a historical and anthropological analysis of this global network of visual representations, underlining how it played a crucial role in the negotiation of geopolitical, colonial and biopolitical relations at the turn of the 20th century, with great bearing on public health consciousness and the social imagination of a new era of globalised hygienic modernity. Research will focus on four regions: China and Japan; India; Africa; South and North America, the first investigated by the Principal Investigator, while the rest being allocated to 3 postdoctoral researchers, all employed full-time in the project. While investigating the visual record of plague in their respective regions, researchers will engage in a collaborative and interdisciplinary analysis of the entangled history of the visual representation of the third pandemic, taking as a common analytical ground 4 different but vitally interlinked aspects of the visual representation of the pandemic: a) the built environment; b) civil disturbance and public order; c) death, corpses and burial; d) race, class and discrimination.";1494262,8;1494262,8;ERC-2013-StG;/ERC-SG;THE UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS;UK;THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;UK;/SOC;1;0;0;1;0;0 98336;272556;MMEP;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-IEF;FP7;Understanding the molecular mechanism of enzymatic processes by a combination of NMR spectroscopy and molecular dynamics simulations;2012-02-01;2014-01-31;;'Essentially all the biochemical processes taking place in living organisms require the intervention of enzymes, which are proteins capable of increasing the rates of chemical reactions by up to 15 orders of magnitude. A detailed definition of the molecular basis of the action of enzymes will not only represent a key advance in our understanding of the fundamental principles of macromolecular behavior, but also provide new opportunities for the rational development of effective treatments for human disease, and for the control of chemical processes in biotechnology. In this application, we propose to characterize in detail the enzymatic processes of two important proteins, cyclophilin A and PagP, by using an interdisciplinary approach in which experimental measurements are incorporated as structural restraints in molecular dynamics simulations. The innovative aspect of this project is the use of chemical shifts, which are the parameters that can be measured most readily and accurately in nuclear magnetic resonance spectroscopy, for protein structure determination. This approach, which has been pioneered in the host lab, enables to determine with high accuracy the structures of proteins in states that are not easily accessible through other types of measurements. We will therefore have the opportunity to gain access to conformations that are invisible by standard methods of structural biology, and in this way to clarify the mechanism of action of two important enzymes.';200049,6;200049,6;FP7-PEOPLE-2010-IEF;/MC-IEF;THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;UK;;;"/EMP;/EDU;/NET";1;0;0;1;0;0 111070;340964;POL1PIC;ONG;FP7-IDEAS-ERC;ERC-AG-LS1;FP7;Dynamic architecture of the RNA polymerase I transcription initiation machinery;2014-02-01;2019-01-31;;RNA polymerase (Pol) I and Pol III synthesize non-translated RNAs including rRNA, 5S RNA, and tRNAs for ribosome assembly and protein synthesis. Pol I and Pol III transcription initiation machineries are carefully regulated in healthy cells, while misregulation of Pol I and Pol III transcription is observed in a variety of cancers. We propose to study the structure and dynamics of the Pol I transcription initiation machinery in a broad and interdisciplinary analysis that combines an integrated structural biology approach with in vitro and in vivo functional analysis, proteomics approaches, integrative modelling and fluorescence microscopy studies. The project builds on our on-going efforts in studying Pol III transcription and first results in the analysis of Pol I transcription, where crystals of the 14-subunit Pol I enzyme diffracting to at least 3.5 ? resolution have been obtained. We will determine the crystal structure of Pol I as second eukaryotic DNA-dependent RNA polymerase structure, and we will also co-crystallize Pol I with nucleic acids and Pol I-specific general transcription factors. A particular focus of the project will be the structural and functional characterization of the Pol I transcription pre-initiation complex (Pol I PIC) that is considerably smaller and compacter as the Pol II PIC. Structural data combined with results from chemical cross-linking and biochemical interaction assays will be used for integrative modeling of the structure and dynamics of Pol I PICs. Fluorescence (cross-) correlation spectroscopy (FCS/FCCS) will monitor Pol I PIC assembly in vivo. Structural information will direct the site-specific fluorescence labeling of Pol I PIC components to monitor conformational changes during Pol I PIC assembly and transcription in vitro. Our results will provide comprehensive, structural, and mechanistic insights into Pol I transcription and the possible role of Pol I in cancer.;2459090;2459090;ERC-2013-ADG;/ERC-AG;EUROPEAN MOLECULAR BIOLOGY LABORATORY;DE;;;"/BIO;/LIF";1;0;0;1;0;0 109687;618743;Mechanicus;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-CIG;FP7;The mechanics of nuclear division and positioning;2014-01-01;2017-12-31;;During mitosis the genetic material of the mother cell is separated and distributed between two daughter cells. Responsible for this coordinated segregation is an assembly of polymers, molecular motors and adapter proteins– the mitotic spindle. This super-molecular machine moves the chromosome halves in opposite directions over impressive cellular scales (tens of µm) within a relatively short time (minutes). The regulatory biochemical pathways responsible for timing and error-control of mitosis have been extensively studied and the key factors have been identified. The major mechanical determinants are thought to be a combination of polymerization dynamics and molecular motor activity but what remains elusive is how such individual processes lead to directed movement in a large cytoskeletal assembly, and how active force generation is balanced to prevent structural collapse. Understanding the mechanical properties responsible for pulling chromosomes is at the heart of spindle function, which is critical to the life cycle of a cell. This knowledge is pivotal in developing biomedical applications. Here, I propose to investigate the mechanical basis leading to directed movement of chromosomes during segregation and how mechanical load is distributed in the spindle throughout mitosis. I plan to unravel the molecular nature of force leading to nuclear migration following segregation, an essential process in large egg cells. The experimental foundation for my studies is a recently developed cell-free assay using the genetically tractable Drosophila, providing complete accessibility to every mitotic event with time-lapse imaging and mechanical manipulation. This project lies at the interdisciplinary interface between mechanical engineering, microscopy, biochemistry and fly genetics. The basic concepts for the planned experiments are speckle microscopy, spatial constraining, mechanical relaxation and compression in combination with genetic and pharmaceutical perturbation.;100000;100000;FP7-PEOPLE-2013-CIG;/MC-CIG;FUNDACAO CALOUSTE GULBENKIAN;PT;;;/LIF;1;0;0;1;0;0 97539;264552;ENTERVISION;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-ITN;FP7;Research Training in 3D Digital Imaging for Cancer Radiation Therapy;2011-02-01;2015-01-31;;"The vision on a future high-precision radiation therapy utilizing either particle or photon beams is a treatment on a technological level which allows for: (1) obtaining information on relevant tumour parameters (volume, position, topology, density - also of the surrounding tissue) during every moment of therapeutic irradiation; (2) adapting the treatment plan in real time; and (3) initiating the appropriate control of the irradiation device to compensate for any deviations from the original treatment plan that compromise a tumour conformal dose delivery. The European training network in digital medical imaging for radiotherapy (ENTERVISION) will be established in response to the critical need for reinforcing research in online 3D digital imaging and the training of professionals in order to deliver some of the key elements and building blocks for realizing the vision for early detection and more precise treatment of tumours. This is an interdisciplinary (physics, medicine, electronics, informatics, radiobiology, engineering) multinational initiative, which has the primary goal of training researchers who will help technical developments at a pan-European level, for the benefit of all of Europe. ENTERVISION brings together ten academic institutes and research centres of excellence and the two leading European companies in particle therapy, IBA and Siemens. All partners are known worldwide in the diverse but complementary fields associated with technological development for improving health. Thus the network covers a unique set of competencies, expertise, infrastructures and training possibilities. The network will train 12 ESR and 4 ER during a 48 month period. The context of a new technique and a dynamic research program in an area of great societal demand offers outstanding training opportunities for future careers of the young researchers.";3817884;3817884;FP7-PEOPLE-2010-ITN;/MC-ITN;EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH;CH;"THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;UNIVERSITE LYON 1 CLAUDE BERNARD;ION BEAM APPLICATIONS SA;GSI HELMHOLTZZENTRUM FUER SCHWERIONENFORSCHUNG Gmbh;AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS;UNIVERSITAETSKLINIKUM HEIDELBERG;FONDAZIONE PER ADROTERAPIA ONCOLOGICA - TERA;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;SIEMENS AKTIENGESELLSCHAFT;TECHNISCHE UNIVERSITAET DRESDEN;ISTITUTO NAZIONALE DI FISICA NUCLEARE";"UK;FR;BE;DE;ES;IT";"/EDU;/NET";1;0;0;1;0;0 110831;329018;D_IN_VIVO;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IEF;FP7;A general law describing the diffusion of membrane proteins in vivo based on single molecule tracking of membrane proteins in Escherichia coli;2014-09-01;2016-08-31;;The ultimate goal of cell biology is to understand how proteins function in real cells and to understand their regulatory mechanisms. To achieve this goal one needs to analyze molecules in their cellular environment and not under idealized test tube conditions. A major difference between in vivo and in vitro conditions is the crowdedness (and associated molecular complexity) of the cytoplasm and biological membranes. As a consequence diffusion in this environment is significantly slower. To make biology more quantitative, we should measure the key parameters such as reaction rates and diffusion coefficients in vivo. Here, I propose an experimental set-up to measure the diffusion of membrane proteins in live bacterial cells. The main objective of this project is to establish a relationship between the diffusion coefficient and number of trans-membrane helices (radius in the membrane) of membrane proteins. The mobility of fluorescently labeled proteins will be probed at the single molecule level in the membranes of a model prokaryotic organism – Escherichia coli. Single molecule tracking of membrane proteins systematically increasing in size (radius in the membrane) will be implemented to obtain a general model of protein diffusion in the membranes. Assigning actual numbers to the parameters of a cell will provide a quantitative context for systems biology efforts and sharpen our understanding of how a cell works. By training-through-research, the fellowship will allow me to learn new techniques (single molecule tracking, programming) and how to build/align microscope set-ups. This will help me transform from a microscope user to a microscope constructor and vastly increase my potential as a cell biologist. In the international and interdisciplinary environment of the host group I will improve my ability to train and manage people, learn to translate my science, across disciplines, to a new audience and to translate fundamental research into industrial applications.;169800;169800;FP7-PEOPLE-2012-IEF;/MC-IEF;KATHOLIEKE UNIVERSITEIT LEUVEN;BE;;;/SCI;1;0;0;1;0;0 107673;327015;MESO-SUPERCELLS;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IEF;FP7;Novel MESO-SUPERstructured solar CELLS with enhanced performance and stability;2014-01-22;2016-01-21;;"The present proposal focuses on the advanced research training of Dr. T. Stergiopoulos on a novel type of 3rd generation solar cells, promising low cost, ease of fabrication and sustainability, called “Meso-superstructured solar cells” (MSSCs). MSSCs were very recently invented by Dr. Snaith in Oxford, and their operation stands between inorganic?organic heterojunction and standard solid-state sensitized-solar cells; the novel and revolutionary concept is that alumina replace titania, acting as a meso-scale scaffold upon which the device is structured and a perovskite is responsible for both visible light absorption and efficient electron conduction. The efficiencies of MSSCs lie at the moment at 10.9 %, limited by the low mobility of the organic hole transport material (spirobifluorene) used to regenerate the perovskite. The proposed research activities aim to make a big step beyond state-of-the-art, realising viable lab-scale devices with efficiencies higher than those of DSCs (>12.4 %) by incorporating fast liquid redox electrolytes in lieu of the low hole mobility spirobifluorene. The expected research results could (i) lead closer towards the commercialization of this new technology, (iii) contribute to the Europe’s continuing research for “clean and efficient energy”, creating reliable “low carbon” solar electricity, and (iv) promote the Excellence of the European Research Area, by building the strongest Photovoltaic research community in the field of 3rd generation solar cells. The fellow will get an interdisciplinary training on the fabrication and fundamentals of this new class of solar cells, also gaining research expertise in state-of-the-art techniques, such as the Photoinduced Absorption Spectroscopy, and acquire complementary/diversifying skills (technology transfer, IP Protection), which will establish his academic future. His outreach activities shall create awareness in the general public of the importance of the Solar Cell research to society.";299558,4;299558,4;FP7-PEOPLE-2012-IEF;/MC-IEF;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;UK;;;/SCI;1;0;0;1;0;0 103859;301443;PlaBioF;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IOF;FP7;Linking living plant traits to soil biogeochemical functions in ecosystem patches under different land use regimes using an isotope-based assessment;2012-10-01;2015-11-30;;Nitrogen cycling is an important aspect of ecosystem functioning and global change. Plants affect soil N cycling through a series of direct and indirect mechanisms. It is therefore essential to understand how human-induced shifts in plant communities modify soil N cycling. One emerging approach to assess these links is by expressing vegetation data based on the functional characteristics (‘traits’) of the plants that make up an ecosystem. In this study, four different land use patches under different historic and present land management within a regional landscape will be selected, and characterized according to their plant functional diversity. Living plant, but not soil effects, on gross N cycling and microbial community structure will be determined using root-permeable cores filled with a common soil, and installed in the land use patches 9-15 months prior to isotope-based N cycling measurements. Statistical RLQ analysis will be used to investigate links between plant traits and biogeochemical ecosystem functioning. The innovative nature of this project lies in the combination of state-of-the-art methods and concepts in plant ecology and biogeochemistry that complement each other in a multi- and interdisciplinary framework. This is achieved by integrating expertise of two research institutions that share a common research interest in global change ecology, but each have a very different conceptual and methodological background in the complementary scientific subdisciplines of plant ecology (outgoing host) and biogeochemistry (return host). The proposal contains a 2-year training period to learn and apply the use of plant trait approaches at one of the worldwide leading institutes in trait-based ecology (Multidisciplinary Institute of Plant Biology, Córdoba, Argentina). The acquired skills and knowledge will be disseminated through several mentoring and tutoring mechanisms at the return host institution (Laboratory of Applied Physical Sciences, Ghent, Belgium).;193405,8;193405,8;FP7-PEOPLE-2011-IOF;/MC-IOF;UNIVERSITEIT GENT;BE;;;/SCI;1;0;0;1;0;0 93506;238541;TRUST;ONG;FP7-PEOPLE;FP7-PEOPLE-ITN-2008;FP7;Training Urology Scientists to develop Treatments;2010-01-01;2014-12-31;;Urinary Incontinence (UI) affects around 10% of the population (more than 70 Million people in the EU) and unfortunately - due to the aging population - is an increasing cause of impaired quality of life. The most common cause of UI is called the Overactive bladder syndrome (OABS) of which the underlying complex bio-molecular mechanisms are poorly understood. Many distinct tissues (nervous system, urothelium, interstitial cells, smooth muscle cells) contribute to OABS but their specific roles remain unknown. As a result, no effective non-invasive therapy without side effects is available or can be developed without a profound integration of multiple scientific disciplines. The TRUST ITN proposes an interdisciplinary research training network of 8 European university institutes and 3 enterprises, with a wide variety of complementary expertise in UI and OABS. The network covers all required disciplines from anatomy, urology, neuroscience, pathology, pharmacology, biomedical engineering, clinical science, bioinformatics to diagnostic- and drug development, that must be applied on cellular-, organ- and whole body levels. Currently most researchers are not trained to deal with such a great variety of disciplines, and are thus insufficiently prepared to cope with the modern and increasingly urgent challenges of urology research. In the TRUST project 10 early stage researchers and 5 experienced researchers will receive training from different leading European research institutes on multiple complementary disciplines that will empower them to explore the and unravel the mechanisms underlying OABS and to develop novel diagnostic, prevention and treatment strategies. Moreover, the integrated research training programme will transfer practical skills, knowledge and experiences to stimulate successful medical (commercial) exploitation of these results. Finally, the unique multidisciplinary scientific profiles of the researchers will open-up promising career perspectives.;3235968;3235968;FP7-PEOPLE-ITN-2008;/MC-ITN;SHEFFIELD TEACHING HOSPITALS NHS FOUNDATION TRUST;UK;"THE UNIVERSITY OF SHEFFIELD;UNIVERSITEIT MAASTRICHT;NORTH BRISTOL NATIONAL HEALTH SERVICE TRUST;WARSZAWSKI UNIWERSYTET MEDYCZNY;UNIVERSITAIR ZIEKENHUIS ANTWERPEN;SHEFFIELD HALLAM UNIVERSITY;Astellas Pharma Europe BV;ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM;KATHOLIEKE UNIVERSITEIT LEUVEN;Plethora Solutions Limited";"UK;NL;PL;BE";"/SCI;/EDU";1;0;0;1;0;0 94921;246749;BIOCARB;ONG;FP7-IDEAS-ERC;ERC-AG-ID1;FP7;Carbonate Biomineralization in the Marine Environment: Paleo-climate proxies and the origin of vital effects;2010-07-01;2015-06-30;;This interdisciplinary proposal has the objective to greatly enhance our understanding of fundamental biomineralization processes involved in the formation of calcium carbonates by marine organisms, such as corals, foraminifera and bivalves, in order to better understand vital effects. This is essential to the application of these carbonates as proxies for global (paleo-) environmental change. The core of the proposal is an experimental capability that I have pioneered during 2008: Dynamic stable isotopic labeling during formation of carbonate skeletons, tests, and shells, combined with NanoSIMS imaging. The NanoSIMS ion microprobe is a state-of-the-art analytical technology that allows precise elemental and isotopic imaging with a spatial resolution of ~100 nanometers. NanoSIMS imaging of the isotopic label(s) in the resulting biocarbonates and in associated cell-structures will be used to uncover cellular-level transport processes, timescales of formation of different biocarbonate components, as well as trace-elemental and isotopic fractionations. This will uncover the origin of vital effects. With this proposal, I establish a new scientific frontier and guarantee European leadership. The technical and scientific developments resulting from this work are broadly applicable and will radically change scientific ideas about marine carbonate biomineralization and compositional vital effects.;2182000;2182000;ERC-2009-AdG;/ERC-AG;ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE;CH;MUSEUM NATIONAL D'HISTOIRE NATURELLE;FR;/SCI;1;0;0;1;0;0 92636;243016;PALMASSEMBLY;ONG;FP7-IDEAS-ERC;ERC-SG-ID1;FP7;Protein assembly: From the molecular scale to the mesoscale with super-resolution imaging;2009-12-01;2015-11-30;;Cellular responses to external signals begin at the plasma membrane, where the dynamic assembly of receptors can regulate cellular activity. Membrane-enveloped viruses, including the human immunodeficiency virus (HIV) also assemble at the plasma membrane, exploiting mechanisms evolved for cellular trafficking. However, our physical paradigm for how proteins form mesoscale assemblies is far from complete. While the organization and dynamics of membrane proteins are heterogeneous, commonly used fluorescence-based measurements lack information at the molecular scale. In contrast, single molecule measurements limited to looking at only a few molecules in a given cell lack ensemble information. Thus, the study of protein assembly has been limited by a lack of spatially resolved, dynamic information on ensembles of molecules. We will use super-resolution fluorescence imaging techniques combined with live cell imaging and single molecule tracking to determine how the dynamics of protein assembly are coordinated. The long-term goal of my research is to use quantitative fluorescence methods to identify the physical mechanisms for protein transport and organization in cells. The objective of this proposal is to establish quantitative models of protein assembly in two specific biological systems which were selected for the distinct characteristics of their assembly, and their relevance to human health. This will test the central hypothesis that molecular assembly is enhanced by the organization of the plasma membrane in the form of cytoskeletal elements and protein-lipid platforms. This interdisciplinary research will provide an experimental foundation for a statistical description of the cell, whose behaviour is embedded in protein organization and dynamics.;1542518;1542518;ERC-2009-StG;/ERC-SG;ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE;CH;;;/SCI;1;0;0;1;0;0 110855;340588;ECAP;ONG;FP7-IDEAS-ERC;ERC-AG-LS4;FP7;Genetic/epigenetic basis of ethnic differences in cancer predisposition;2014-02-01;2020-01-31;;"'Integration of large scale genetic and epigenetic analysis needs to be coupled with well defined biological hypotheses that can be experimentally tested. This project is aimed at developing a novel integrated approach to understand genetic and epigenetic predisposition to cancer with skin as model system. The Caucasian (West European) and Asian (East Asian) populations differ substantially in their predisposition to skin cancer, specifically Squamous Cell Carcinoma (SCC). The underlying mechanisms are poorly understood. As in other organs, skin SCC results from changes in both epithelial and mesenchymal compartments. We will be focusing on two key gene regulatory networks of cells of the two compartments (keratinocytes and dermal fibroblasts), with a key role in skin SCC. The 'keratinocyte network' has Notch/p53/p63 as key nodes, while the 'dermal fibroblast network' had Notch and AP1 family members. We will pursue two main goals : 1) We will test the hypothesis that a linkage can be established between specific genetic and epigenetic marks in the Caucasian versus Asian populations and differences in expression and function of 'keratinocyte and/or dermal fibroblast network genes'. 2) We will test the hypothesis that keratinocytes and/or dermal fibroblasts of Caucasian versus Asian individuals differ in their tumor yielding capability, and that these differences in cancer forming capability are due to differences in either 'keratinocyte or dermal fibroblast network genes'. The applicant is a world leader in epithelial signaling and cancer biology, and is heading interdisciplinary research efforts that bridge the basic and clinical sciences. Together with his bioinformatician and clinician collaborators, he is in an excellent position to attain the high goals of the proposal. The approach has not been attempted before, is only possible within the frame of an advanced ERC grant, and has substantial basic as well as translational/clinical implications.'";2495425;2495425;ERC-2013-ADG;/ERC-AG;UNIVERSITE DE LAUSANNE;CH;;;"/LIF;/MED;/MBI";1;0;0;1;0;0 108345;334090;OPT-GEOM-RS;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-CIG;FP7;Optimization Problems on Geometric Range Spaces;2014-09-01;2018-08-31;;"Computational geometry is a subfield of theoretical computer science devoted to the design and implementation of geometric algorithms, as well as to their analysis, and to the combinatorial structure that they manipulate. In particular, computational geometry encompasses a diversity of optimization problems. It is often infeasible in practice to find the optimal solution of a geometric optimization problem. This is because the optimum might typically be hard to compute. This suggests that instead of insisting on computing the exact solution for optimization problems, one should be satisfied with a possibly suboptimal solution that approximates the optimum reasonably well. The goal of this proposal is to consider optimization problems involving geometric objects in low dimensions, and design efficient algorithms that guarantee a good approximation for their solutions. Such problems have been well studied in abstract settings (that is, when the objects are abstract and no geometric properties are known), but their geometric variants have received much less attention, and the solutions to most of these problems have still remained elusive. This project suggests an interdisciplinary challenge. On the theoretical front, it aims to develop a set of mathematical tools taken from discrete geometry, such as geometric arrangements and epsilon nets, which exploit the geometric structure of the given setting. In fact, such tools can be exploited on a broader set of problems, and lie beyond the scope of the problems presented in this proposal. On the applied front, this problems have applications to other disciplines as sensor networking, computer graphics, geographic information systems, machine learning and more. In fact, the PI is collaborating with researchers from sensor networking and learning where she applies such mathematical tools in order to solve problems from the real world.";100000;100000;FP7-PEOPLE-2012-CIG;/MC-CIG;TEL AVIV UNIVERSITY;IL;;;/LIF;1;0;0;1;0;0 108451;331432;Cognition in science;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IEF;FP7;Science as extended cognition: The role of material culture in scientific reasoning;2013-10-01;2015-09-30;;"Historical and sociological studies show the importance of the material culture of science, including external representations, tools and instruments, and the physical layout of the laboratory. And yet these aspects of science are often assumed to be incidental to scientific reasoning itself. Recent developments in cognitive science challenge this assumption, revealing that many cognitive tasks are performed not by internal thought processes alone, but through skilful exploitation of material representations, tools and the wider environment. In fact, according to the thesis of ‘extended’ cognition, the relationship between internal thought and external objects is sometimes so close that external objects become part of the cognitive process. Using methods from cognitive ethnography, this project will carry out three in-depth empirical studies, each focusing on a particular aspect of the material culture of science. These studies will ask: What is the precise nature of scientists’ interaction with external, material devices? Which, if any, of these interactions might count as extended cognition? The final stage of the project will explore the profound implications of extended cognition for a range of issues in philosophy of science, including the nature of scientific theories and the relationship between science and culture. The project will be highly interdisciplinary, drawing on and contributing to philosophy, cognitive science and history and sociology of science. By offering a new understanding of reasoning in scientific practice, the project will also contribute to wider issues of public concern, such as the role of expertise in policy-making and the nature of science education. In addition, it will significantly enhance the career development of the researcher, allowing him to learn important new skills (e.g. in cognitive science and ethnographic methods) in a unique, world-leading centre for the study of extended cognition and its philosophical implications.";231283,2;231283,2;FP7-PEOPLE-2012-IEF;/MC-IEF;THE UNIVERSITY OF EXETER;UK;THE UNIVERSITY OF EDINBURGH;UK;/SCI;1;0;0;1;0;0 95094;257106;NAMASTE;ONG;FP7-IDEAS-ERC;ERC-SG-PE10;FP7;Thermodynamics of the Climate System;2010-09-01;2015-08-31;;"The investigation of the global structural properties of the climate system (CS) plays a central role for the provision of a unifying picture of climate variability and climate change on a large variety of scales and is of outstanding importance for the quest for reliable metrics to be used in the validation of climate models (CMs). The CS can be seen as a complex, non-equilibrium system, transforming potential into mechanical energy as a thermal engine, generating entropy by irreversible processes, and keeping an approximate steady state by balancing the thermodynamic fluxes with the surrounding environment. We move from the thermodynamical perspective pioneered by Lorenz by means of theoretical studies, numerical simulations performed with hierarchies of CMs, ranging from minimal models to state-of-the-art coupled atmosphere-ocean models, and, where possible, observations. We take advantage of both the tools of the phenomenological theory of non-equilibrium thermodynamics and, from a more fundamental point of view, of the recent developments of non-equilibrium statistical mechanics, along the lines of the response theory developed by Ruelle. The main goals of this interdisciplinary project can be summarized as follows: - Advances in the thermodynamic description of the CS and planetary bodies, re-analysis of the hydrological cycle and of the atmosphere- ocean interaction; - Thermodynamic re-examination of mechanisms involved in past, present and future climate variability and change with CMs of various degrees of complexity; - Definition and implementation of a new generation of diagnostic tools for auditing CMs and for analysing observative (satellite) data; - Application of the response theory and Kramers-Kronig relations to CMs of various degrees of complexity for analysing generalized climate sensitivities and climate response to periodic forcings; - Analysis of the impact of stochastic perturbations on the statistical properties of the forced and free fluctuations of simplified CMs; - Study of the climatic tipping points and feedbacks by analysis of the resonances and divergence of the climatic response, and by investigation of the fluctuations of the large scale thermodynamical properties.";1393440;1393440;ERC-2010-StG_20091028;/ERC-SG;UNIVERSITAET HAMBURG;DE;THE UNIVERSITY OF READING;UK;"/PSE;/ENV;/EAR";1;0;0;1;0;0 97826;266445;VECTORS;ONG;FP7-KBBE;Ocean.2010-2;FP7;Vectors of Change in Oceans and Seas Marine Life, Impact on Economic Sectors;2011-02-01;2015-01-31;http://www.marine-vectors.eu/;"Marine life makes a substantial contribution to the economy and society of Europe. VECTORS will elucidate the drivers, pressures and vectors that cause change in marine life, the mechanisms by which they do so, the impacts that they have on ecosystem structures and functioning, and on the economics of associated marine sectors and society. VECTORS will particularly focus on causes and consequences of invasive alien species, outbreak forming species, and changes in fish distribution and productivity. New and existing knowledge and insight will be synthesised and integrated to project changes in marine life, ecosystems and economies under future scenarios for adaptation and mitigation in the light of new technologies, fishing strategies and policy needs. VECTORS will evaluate current forms and mechanisms of marine governance in relation to the vectors of change. Based on its findings, VECTORS will provide solutions and tools for relevant stakeholders and policymakers, to be available for use during the lifetime of the project. The project will address a complex array of interests comprising areas of concern for marine life, biodiversity, sectoral interests, regional seas, and academic disciplines as well as the interests of stakeholders. VECTORS will ensure that the links and interactions between all these areas of interest are explored, explained, modelled and communicated effectively to the relevant stakeholders. The VECTORS consortium is extremely experienced and genuinely multidisciplinary. It includes a mixture of natural scientists with knowledge of socio-economic aspects, and social scientists (environmental economists, policy and governance analysts and environmental law specialists) with interests in natural system functioning. VECTORS is therefore fully equipped to deliver the integrated interdisciplinary research required to achieve its objectives with maximal impact in the arenas of science, policy, management and society.";16581571,69;12484835;FP7-OCEAN-2010;/CP-IP;PLYMOUTH MARINE LABORATORY;UK;"AARHUS UNIVERSITET;TARTU ULIKOOL;UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN;UNIVERSITE DE ROUEN NORMANDIE;KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW;UNIVERSITAET HAMBURG;COMMISSION INTERNATIONALE POUR L'EXPLORATION SCIENTIFIQUE DE LA MER MEDITERRANEE (CIESM);HELLENIC CENTRE FOR MARINE RESEARCH;STICHTING NIOZ, KONINKLIJK NEDERLANDS INSTITUUT VOOR ONDERZOEK DER ZEE;UNIVERSITE DE BRETAGNE OCCIDENTALE;SIR ALISTER HARDY FOUNDATION FOR OCEAN SCIENCE;LEIBNIZ-INSTITUT FUR OSTSEEFORSCHUNG WARNEMUNDE STIFTUNG;THE UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS;THE SECRETARY OF STATE FOR ENVIRONMENT, FOOD AND RURAL AFFAIRS;AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS;FONDAZIONE ENI ENRICO MATTEI;JOHANN HEINRICH VON THUENEN-INSTITUT, BUNDESFORSCHUNGSINSTITUT FUER LAENDLICHE RAEUME, WALD UND FISCHEREI;UNIVERSITA DI PISA;ISRAEL OCEANOGRAPHIC AND LIMNOLOGICAL RESEARCH LIMITED;CONSIGLIO NAZIONALE DELLE RICERCHE;INSTYTUT OCEANOLOGII POLSKIEJ AKADEMII NAUK;UNIVERSITA DEGLI STUDI DI PAVIA;STICHTING DELTARES;ISTITUTO NAZIONALE DI OCEANOGRAFIA E DI GEOFISICA SPERIMENTALE;Community of European Shipyards Associations asbl;CONSORZIO NAZIONALE INTERUNIVERSITARIO PER LE SCIENZE DEL MARE;DANMARKS TEKNISKE UNIVERSITET;INSTITUT FRANCAIS DE RECHERCHE POUR L'EXPLOITATION DE LA MER;INSTITUT FUER OSTSEEFORSCHUNG WARNEMUENDE AN DER UNIVERSITAET ROSTOCK;UNIVERSITY OF HULL;KLAIPEDOS UNIVERSITETAS;WAGENINGEN UNIVERSITY;ACONDICIONAMIENTO TARRASENSE ASSOCIACION;INSTITUT SUPERIEUR DES SCIENCES AGRONOMIQUES, AGROALIMENTAIRES, HORTICOLES ET DU PAYSAGE;BANGOR UNIVERSITY;AALBORG UNIVERSITET;UNIVERZA V LJUBLJANI;GOLLASCH STEPHAN - GOLLASCH CONSULT;STICHTING WAGENINGEN RESEARCH";"DK;EE;IE;FR;NL;DE;MC;EL;UK;ES;IT;IL;PL;BE;LT;SI";/ENV;1;0;0;1;0;0 109586;607937;SUPOLEN;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-ITN;FP7;Supramolecular assembly of polymeric structures: a novel route to enhance soft materials properties;2013-10-01;2017-09-30;;"'Supramolecular polymeric assemblies represent an emerging, promising class of systems with superior versatility compared to their covalent polymeric counterparts. They offer exciting new opportunities for stimuli-responsive structures exhibiting reversible tunable properties, with applications in foodstuff, coatings , cost-efficient processes or biomedical areas. To explore their potential and define strategies for designing novel materials amenable to contemporary needs, a fundamental understanding of their very complex and diverse multiscale supramolecular structure and dynamics is needed. In this regard, a synergy of synthetic chemistry (including both model and industrial systems), physical experiment and modeling are necessary. The objective of SUPOLEN is to understand and tailor the structure and dynamics of supramolecular polymers based on well-defined building blocks, mainly monodisperse linear and star-like polymers. The systematic, thorough study of their behavior offers many possibilities for tailoring their organization and dynamic response, and allows tackling important questions such as (1) understanding the combined effect of the dynamics of the associating groups (strength, position, number and nature) and the internal dynamics of the building blocks (entanglements and architecture); (2) exploring the role played by external stimuli; (3) investigating their behavior in solution as well as in the melt; and (4) developing predictive tools for designing new materials. The proposal is highly interdisciplinary and inter-sectorial, the groups involved are world-leaders in their fields, and the tasks and partners are strategically linked. SUPOLEN reflects European leadership in the field. It offers young researchers a unique training platform with appropriate exposure to a broad range of emerging topics in soft matter and to the industrial sector. It will provide them with the needed tools for addressing relevant scientific and technological challenges.'";3901493,1;3901493,1;FP7-PEOPLE-2013-ITN;/MC-ITN;UNIVERSITE CATHOLIQUE DE LOUVAIN;BE;"DSM MATERIALS SCIENCE CENTER BV;UNIVERSITEIT TWENTE;UNIVERSITA DEGLI STUDI DI NAPOLI FEDERICO II.;FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS;UNIVERSITE DE MONTPELLIER;UNIVERSITY OF LEEDS;DANMARKS TEKNISKE UNIVERSITET;UNIVERSITE MONTPELLIER 2 SCIENCES ET TECHNIQUES;RHODIA OPERATIONS;KATHOLIEKE UNIVERSITEIT LEUVEN";"NL;IT;EL;FR;UK;DK;BE";/LIF;1;0;0;1;0;0 89680;218309;IAPP@RANPLAN;ONG;FP7-PEOPLE;PEOPLE-2007-3-1-IAPP;FP7;IAPP for @utomatic Radio Access Network PLANning and optimisation (IAPP@RANPLAN);2008-11-01;2012-10-31;;The aim of this project is to establish lasting relationships between Ranplan, and two academic partners to research and develop automatic planniong and optimisation (P&O) tools for emerging broadband radio access networks such as HSPA (High Speed Packet Access) and WiMAX and the hybrids of such networks with UMTS and Wi-Fi, i.e., Heteregeneous Radio Access Network (HRANs). The research topics are very important for EU's ICT infrastructure. The project is highly interdisciplinary as it covers wireless communications, Operations Research (OR), and High End Computing (HEC).;1811914;1811914;FP7-PEOPLE-2007-3-1-IAPP;/MC-IAPP;UNIVERSITY OF BEDFORDSHIRE;UK;"LINKOPINGS UNIVERSITET;RANPLAN WIRELESS NETWORK DESIGN LTD";"SE;UK";/EDU;1;0;0;1;0;0 110116;618240;EURINDIS;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-CIG;FP7;European Representations of India and Islam: The Jesuit mission at the Mughal court (1580-1773);2013-10-01;2017-09-30;;The goal of this 48 months proposal is to contribute to a comprehensive understanding of the ways Islam and the Mughal Empire were interpreted and represented in Europe during the early modern period. The chronological delimitation of the subject of this project includes the late sixteenth-century, and the whole seventeenth and eighteenth centuries. This period corresponds to the end of the Portuguese monopoly on the sea route to India, the arrival of the English, Dutch and French companies in Asia, the great missionary experiences of the Jesuits in Asia, the expansion and decline of the Mughal Empire in India, the Enlightenment and the emergence of Indology and Orientalism as academic disciplines. The applicant is a specialist on the European presence in India during the early modern period. Although this project starts in that disciplinary field, one of its aims is to develop a distinctive historiographical approach based on a systematic interaction with disciplines such as anthropology and sociology, by adopting a conceptual framework based on the concepts of ‘contact zone’ and ‘go-between’. Through this interdisciplinary approach, this project aims to contribute to the current debates on Orientalism and Islam.;100000;100000;FP7-PEOPLE-2013-CIG;/MC-CIG;THE UNIVERSITY OF LIVERPOOL;UK;UNIVERSIDAD POMPEU FABRA;ES;/LIF;1;0;0;1;0;0 97645;265103;MEDSEA;ONG;FP7-ENVIRONMENT;ENV.2010.1.1.5-1;FP7;MEDiterranean Sea Acidification in a changing climate;2011-02-01;2014-07-31;;"Increases of atmospheric CO2 and associated decreases in seawater pH and carbonate ion concentration this century and beyond are likely to have wide impacts on marine ecosystems including those of the Mediterranean Sea. Consequences of this process, ocean acidification, threaten the health of the Mediterranean, adding to other anthropogenic pressures, including those from climate change. Yet in comparison to other areas of the world ocean, there has been no concerted effort to study Mediterranean acidification, which is fundamental to the social and economic conditions of more than 130 million people living along its coastlines and another 175 million who visit the region each year. The MedSeA project addresses ecologic and economic impacts from the combined influences of anthropogenic acidification and warming, while accounting for the unique characteristics of this key region. MedSeA will forecast chemical, climatic, ecological-biological, and socio-economical changes of the Mediterranean driven by increases in CO2 and other greenhouse gases, while focusing on the combined impacts of acidification and warming on marine shell and skeletal building, productivity, and food webs. We will use an interdisciplinary approach involving biologists, earth scientists, and economists, through observations, experiments, and modelling. These experts will provide science-based projections of Mediterranean acidification under the influence of climate change as well as associated economic impacts. Projections will be based on new observations of chemical conditions as well as new observational and experimental data on the responses of key organisms and ecosystems to acidification and warming, which will be fed into existing ocean models that have been improved to account for the Mediterranean´s fine-scale features. These scientific advances will allow us to provide the best advice to policymakers who must develop regional strategies for adaptation and mitigation.";4824146,36;3490169,35;FP7-ENV-2010;/CP-FP;UNIVERSITAT AUTONOMA DE BARCELONA;ES;"UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6;PLYMOUTH MARINE LABORATORY;HELLENIC CENTRE FOR MARINE RESEARCH;COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES;National Institute of Oceanography and Fisheries;UNIVERSITE DE PERPIGNAN;UNIVERSITY OF PLYMOUTH;AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS;ALFRED-WEGENER-INSTITUT HELMHOLTZ-ZENTRUM FUR POLAR- UND MEERESFORSCHUNG;BAR ILAN UNIVERSITY;ISTITUTO NAZIONALE DI OCEANOGRAFIA E DI GEOFISICA SPERIMENTALE;CONSORZIO NAZIONALE INTERUNIVERSITARIO PER LE SCIENZE DEL MARE;SFAX UNIVERSITY;FONDAZIONE CENTRO EURO-MEDITERRANEO SUI CAMBIAMENTI CLIMATICI;INSTITUT NATIONAL DE RECHERCHE HALIEUTIQUE";"FR;UK;EL;EG;ES;DE;IL;IT;TN;MA";"/SEA;/ENV;/CCC";1;0;0;1;0;0 109589;608382;TRIPOD;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-ITN;FP7;Training & Research Involving Polymer Optical Devices;2013-10-01;2017-09-30;;"The project is located in the field of optical fibre sensors - an area where Europe has developed internationally competitive research and commercial activity. The aim is to significantly extend the range of application of optical fibre grating sensors by developing a mature version of the technology in polymer optical fibres and thereby increase European competitiveness. Polymer fibres offer some key advantages over silica, the two most important perhaps being the ability to sense much higher strains and the considerably reduced stiffness of the plastic compared to the glass fibre. Polymers are however complex materials and the properties of a sensor in this material are dependent on all stages of the sensor fabrication process, from initial preform production, through fibre drawing to grating fabrication. In TRIPOD we have brought together an interdisciplinary scientific team with expertise covering all aspects of the sensor fabrication path to enable us to obtain a full understanding of the process, with the aim of enabling us to produce optimised grating sensors, efficiently, repeatably and reliably. Integral to the programme are end-user companies who will provide direction on sensor development and training to the researchers on business issues, as well as familiarising themselves with the new technology, enabling them to expand their business models. In addition, we include technology innovators to open up further applications and potential markets.";3089229;3089229;FP7-PEOPLE-2013-ITN;/MC-ITN;ASTON UNIVERSITY;UK;"TECHNOLOGIKO PANEPISTIMIO KYPROU;IBSEN PHOTONICS AS;MEDTRONIC R&D DIABETES DENMARK AS;BUNDESANSTALT FUER MATERIALFORSCHUNG UND -PRUEFUNG;DANMARKS TEKNISKE UNIVERSITET;UNIWERSYTET MARII CURIE-SKLODOWSKIEJ;UNIVERSIDAD CARLOS III DE MADRID";"CY;DK;DE;PL;ES";/LIF;1;0;0;1;0;0 96276;260481;MOBA-CS;ONG;FP7-IDEAS-ERC;ERC-SG-LS1;FP7;The molecular basis of Cockayne Syndrome;2011-01-01;2015-12-31;;"Cockayne syndrome is a congenital disease with impaired DNA repair in actively transcribed genes. Affected children show developmental abnormalities and signs of premature aging. Cockayne syndrome is caused by mutations in the Cockayne syndrome complementation group A (CSA) and B (CSB) genes. While CSB encodes a SWI/SNF ATPase that likely assists the stalled RNA polymerase in overcoming lesions, CSA’s detailed role in repair has so far remained elusive. CSA is part of the DDB1-CSA-Cul4-Rbx1 E3 ubiquitin ligase complex. The available data suggest that CSA may function as a substrate adaptor for ubiquitination by the DDB1-Cul4-Rbx1 ligase. I will pursue a novel structure-driven proteomic approach to identify the substrate epitope recognized by the DDB1-CSA-Cul4-Rbx1 E3 ubiquitin ligase. These experiments aim to provide the important missing signal required for recruitment of the ligase complex to sites of stalled RNA polII complexes. Importantly, the CSA ligase, as it arrives at sites of DNA damage, is inactive. Our comprehensive structural and biochemical efforts will thus include the mechanisms of regulation of the CSA ubiquitin ligase activity by activators and inhibitors following recruitment to the repair site. MoBa-CS will not only improve our understanding of CSA’s molecular role in Cockayne syndrome, but also reveal CSA’s mode of action within the essential transcription coupled repair pathway. Understanding the cellular signals overseeing transcription coupled repair will provide important insights into how the pathway is integrated within the overall DNA damage response circuitry of the cell. ERC funding would enable us to pursue an interdisciplinary proteomic and structure based approach in examining DDB1-CSA function.";1499235;1499235;ERC-2010-StG_20091118;/ERC-SG;FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION;CH;Novartis Forschungsstiftung;CH;"/BIO;/LIF";1;0;0;1;0;0 101596;281591;RESISTEVO;ONG;FP7-IDEAS-ERC;ERC-SG-ID1;FP7;The evolution of antibiotic resistance: integrating molecular mechanisms of resistance and evolutionary context;2012-01-01;2016-12-31;;'The evolution of antibiotic resistance poses an important threat to human health and welfare. Antibiotic resistance is accompanied by fitness costs that have been shown to play a key role in the spread of resistance. These costs are variable, but the underlying ecological and genetic causes of this variation remain obscure. Unfortunately, bacteria can adapt to the cost of resistance by compensatory mutations, and this permits resistance to be maintained in pathogen populations after antibiotics have been withdrawn from use. Resistance mutations vary in their potential for compensatory adaptation, but the causes of this variation remain unknown. In this project, we will determine how the molecular mechanisms of antibiotic resistance and the (i) ecological and (ii) genetic context in which resistance evolves interact to determine (a) the fitness costs associated with antibiotic resistance and (b) the potential and mechanisms for adaptation to the cost of resistance. Conceptually, we will approach this problem using an interdisciplinary approach that combines theory from population genetics and systems biology into the same evolutionary framework. To carry out this research program, we will use high-throughput experimental evolution of resistance to the broad-spectrum antibiotic rifampicin in bacteria from the genus Pseudomonas. This research approach will allow us to measure both the costs of resistance and the (i) rate and (ii) mechanisms of compensation for this cost at an unprecedented scale. The results of this research program will provide key insights into the underlying drivers of resistance emergence and persistence, and it may ultimately be possible to apply the insights from this research program to help combat resistance in pathogen populations. At a more conceptual level, this research will provide an important experimental test of the roles of chance, necessity, and historical contingency in shaping the rate and mechanisms of adaptation.';1196639;1196639;ERC-2011-StG_20101109;/ERC-SG;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;UK;;;/SCI;1;0;0;1;0;0 94598;256317;ECO-URB;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-RG;FP7;Analysing Urban Metabolism and Ecological Footprint - A Multi-Scale Approach to Urban Sustainability Accounting and its Policy Implications;2010-04-01;2014-03-31;;Today, at the beginning of the 21st century, the majority of the world’s population are living in urban areas, generating significant pressure on the supporting ecosystems. As the available means (i.e., financial and political) to change urban activities, design and lifestyle are limited, it is imperative to identify those sectors and activities with the potential to contribute the most to minimising the urban environmental load and increasing sustainability. Two approaches that are being used to quantify and assess urban sustainability are “urban metabolism” and “ecological footprint analysis”. However, these approaches need to be further developed to better reflect the complexity and unique characteristics of specific urban areas and activities. In the proposed research, I will develop a multi-scale analysis of the urban metabolism and footprint. By combining the above two approaches, I will identify the specific urban activities that contribute the most to urban throughput and will illustrate the gap to sustainability. By uniquely combining top-down (i.e., using secondary data sources) and bottom-up (i.e., surveys and focus groups) data gathering methods, this project will breakdown the studied urban activities into their specific components at the household to the city scales. By combining quantitative and qualitative approaches this research will be able to examine existing and suggested measures (e.g., policies, technologies) and to inform decision makers as to the required directions. This interdisciplinary research will combine data from the social and natural sciences with engineering. It is expected to contribute to the emerging fields of environmental accounting and sustainability sciences as well as to urban and regional planning and public policy. It has the potential to serve as a basis for other urban sustainability studies in Europe and for future collaboration and mutual fertilization with other researchers in the ERA.;100000;100000;FP7-PEOPLE-2009-RG;/MC-IRG;BEN-GURION UNIVERSITY OF THE NEGEV;IL;;;/SCI;1;0;0;1;0;0 101456;289485;OPAC;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-ITN;FP7;"optimization of Particle Accelerators: A Marie Curie Initial Training Network";2011-12-01;2015-11-30;;"There are more than fifteen thousand particle accelerators in the world, ranging from the linear accelerators used for cancer therapy in modern hospitals to the giant 'atom-smashers' at international particle physics laboratories used to unlock the secrets of creation. For many decades these scientific instruments have formed one of the main pillars of modern research across scientific disciplines and countries. The optimization of the performance of any particle accelerator critically depends on an in-depth understanding of the beam dynamics in the machine, the availability of simulation tools to study and continuously improve all accelerator components from beam handling elements to rf cavities, a complete set of beam diagnostics methods to monitor all important machine and beam parameters with high precision, and a control and data acquisition system that links all the above. The oPAC consortium proposes to carry out collaborative research into all the above aspects, with the aim to optimize the performance of present and future accelerators that lie at the heart of many research infrastructures. The network brings together leading research centers, universities, and industry partners to jointly train the next generation of researchers in this interdisciplinary field. oPAC aims at developing long term collaboration and links between the involved teams across sectors and disciplinary boundaries and to thus help defining improved research and training standards in this important field.";5939699;5939699;FP7-PEOPLE-2011-ITN;/MC-ITN;THE UNIVERSITY OF LIVERPOOL;UK;"COSYLAB LABORATORIJ ZA KONTROLNE SISTEME DD;SYNCHROTRON SOLEIL SOCIETE CIVILE;CONSORCIO PARA LA CONSTRUCCION EQUIPAMIENTO Y EXPLOTACION DEL LABORATORIO DE LUZ SINCROTRON;GSI HELMHOLTZZENTRUM FUER SCHWERIONENFORSCHUNG Gmbh;CST - COMPUTER SIMULATION TECHNOLOGY AG;INSTRUMENTATION TECHNOLOGIES, ELEKTRONSKA INSTRUMENTACIJA IN PRODUKTI ZA PROCESIRANJE SIGNALOV DD;EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH;CIVIDEC INSTRUMENTATION GMBH;EUROPEAN SPALLATION SOURCE ESS AB;ROYAL HOLLOWAY AND BEDFORD NEW COLLEGE;UNIVERSIDAD DE SEVILLA";"SI;FR;ES;DE;CH;AT;SE;UK";"/LIF;/SCI";1;0;0;1;0;0 110239;338229;WAROFWORDS;ONG;FP7-IDEAS-ERC;ERC-SG-SH6;FP7;A War of Words: What Ancient Manchurian History Does to Korea and China Today;2013-10-01;2018-09-30;;"The past is not past. Ancient history can influence the present day, affecting diplomatic and economic ties between states, and galvanizing public discourse and cultural expression. Since 2003, South Korea and China have been embroiled in a territorial dispute - over ancient states that ceased to exist as such over a millennium ago, in then Manchuria. Both sides have invested hundreds of millions of dollars in establishing the legitimacy of their claims, subsidizing academic research and publicity campaigns. Strategically positioned in the middle lies North Korea, its roots extending deeply into Manchurian history, and the object of Chinese strategic interests. The confrontation has appealed to the popular imagination in both countries. Amateur historians, artists, and film makers have voiced their opinions in writing, art, movies, and TV, in traditional and new (online) media. Why does the past elicit this intense activity in the present? What does the past mean for the present, and what does it do to it? A WAR OF WORDS will engage this complex of Chinese claims to Manchu-Korean ancient history, South Korean reactions, public discourse and cultural expression in both states, and the role of North Korea. It will approach these issues from an interdisciplinary angle, as an interconnected whole of contemporary national interests, strategic visions for the future of Northeast Asia, revisionist ancient history, and notions of national identity. It will critically review historiography of Manchuria through the ages; chart policy-driven uses and abuses of history in academia and the public domain in the Koreas and China; and complement and challenge habitual IR and security studies perspectives on Northeast Asia, particularly North Korea, by foregrounding ancient Manchurian history and its politico-socio-cultural manifestations in the present. As such, it will radically alter our understanding of a region of tremendous geopolitical, ­economic, and ­cultural importance.";1499955;1499955;ERC-2013-StG;/ERC-SG;UNIVERSITEIT LEIDEN;NL;;;"/SCI;/SOC";1;0;0;1;0;0 109788;606786;ImResFun;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-ITN;FP7;Molecular Mechanisms of Fungal Pathogen Host Interactions;2013-10-01;2017-09-30;;ImResFun shall provide state-of-the-art training in infectious disease research and medical immunology targeting the most common human fungal pathogens, the opportunistic Candida species. The key objectives of ImResFun are: (i) to understand how immune cells and infected organs respond to invasion by Candida spp, (ii) to decipher host-defense mechanisms mediating pathogen elimination, and (iii) to identify genetic networks driving the dynamics of host-pathogen interplay. ImResFun will exploit cutting-edge technologies to unravel the basic mechanisms of fungal pathogenesis and host immunity, and to improve diagnosis and identify novel biomarkers of infection. Importantly, ImResFun will translate research into clinical practice and identify potential targets for antifungal drug discovery. ImResFun has seven WPs. In addition to coordination (WP7), research will cover molecular mechanisms of host-pathogen interactions using dual-system infection biology in vitro and in vivo (WP1), clinical patient setting and age-related infections (WP2), chemical biology and antifungal drug development (WP3), and bioinformatics and genome-wide data analysis (WP4). A compulsory and tailor-made practical course (WP5) and complementary skills (WP6) program will boost hypothesis-driven projects. Meaningful exposure to the private sector is ensured by extensive secondments of all ESRs/ERs. The resulting reciprocal technology transfer will be beneficial for both SMEs and ESR/ER hosts and sustain collaborations among partners. ImResFun will use personalized career development plans for each ESR/ER to train entrepreneurial scientists capable of translating frontier research into clinical practice, biotechnology and drug discovery. Taken together, ImResFun offers a best-practice example for interdisciplinary, intersectorial and supradisciplinary training in understanding the immunology of microbial infectious diseases, since most approaches are amenable to other microbial pathogens.;3591515;3591515;FP7-PEOPLE-2013-ITN;/MC-ITN;MEDIZINISCHE UNIVERSITAET WIEN;AT;"FYZIOLOGICKY USTAV AKADEMIE VED CESKE REPUBLIKY VEREJNA VYZKUMNA INSTITUCE (VVI);LABDIA LABORDIAGNOSTIK GMBH;FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.;QIAGEN AARHUS AS;UNIVERSIDAD COMPLUTENSE DE MADRID;EMC MICROCOLLECTIONS GMBH;UNIVERSITAETSMEDIZIN GOETTINGEN - GEORG-AUGUST-UNIVERSITAET GOETTINGEN - STIFTUNG OEFFENTLICHEN RECHTS;SZEGEDI TUDOMANYEGYETEM;FUNDACIO CENTRE DE REGULACIO GENOMICA;KING'S COLLEGE LONDON;STOCKHOLMS UNIVERSITET";"CZ;AT;DE;DK;ES;HU;UK;SE";/LIF;1;0;0;1;0;0 98082;267100;LIQAD;ONG;FP7-IDEAS-ERC;ERC-AG-PE2;FP7;Long-range interacting quantum systems and devices;2011-03-01;2016-02-29;;"Controlled correlations in a quantum network are at the heart of emerging quantum technologies for communication, information processing and computation. The scaling to a large number of interconnected nodes has so far remained an open challenge. Here mesoscopic ensembles of atoms which can be well controlled in their geometry and which provide rapidly switchable long range interactions promise an alternative approach with a significant simplification for quantum devices and networks. Finite temperatures up to even above room temperature operation of the resulting quantum devices might be possible and the upscaling to quantum networks with millions of nodes seems within reach. Therefore I propose to study Rydberg interacting mesoscopic ensembles at low and high temperatures. In the first part fundamental building blocks for quantum devices and networks based on the so called Rydberg blockade in mesoscopic ensembles will be studied in an ultracold environment. In the second part I will investigate how to transfer these ideas to scalable ensembles in thermal micro-vapor cells. As the range of interaction can be on the order of micrometers, standard techniques in lithography can be used to produce mesoscopic ensembles confined in glass cells. Display fabrication technologies used for the production of TFT LC (thin-film transistor liquid crystal) displays can be used to scale the number of connected mesoscopic ensembles up dramatically. I will investigate to what extend the interdisciplinary combination of micro- and display technology and atomic physics enables the parallel operation of many scalable single photon sources for example to feed a large linear optical quantum network. This resulting ground-breaking perspective for the applicability of quantum devices and networks justifies the risk to explore fundamentally and technologically unexplored territory.";2407200;2407200;ERC-2010-AdG_20100224;/ERC-AG;UNIVERSITAET STUTTGART;DE;;;"/PSE;/SCI";1;0;0;1;0;0 109921;600406;IARC Fellows II;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-COFUND;FP7;IARC International Fellowships Programme;2013-10-01;2018-09-30;;"The mission of the International Agency for Research on Cancer (IARC) is to promote international collaboration in cancer research for cancer prevention and control. One of the statutory functions of IARC is the training and education. The Agency seeks to achieve this aim through IARC’s International Fellowship Programme and its International Courses Programme which are designed to assist the development of cancer research and prevention in all countries, with special emphasis on low- and medium-income countries (LMICs) in which such work is not well established, and to train future collaborators in the scientific programme of the Agency. The aim of IARC’s Postdoctoral Fellowships is to provide young scientists from any country with training in a research Group at the Agency in aspects of cancer research ranging from biostatistics and epidemiology (including genetic and molecular) to mechanisms of carcinogenesis, with an emphasis on interdisciplinary projects. The choice of the host group is made by the Fellows. IARC is particularly committed to promoting the development of expertise in cancer research in LMICs countries by training researchers from these countries who can return to their own country to implement and develop programmes in cancer research or cancer control. IARC offers a supportive research environment, in which individuals are valued, encouraged and supported. Ample opportunities of formal and informal training are offered in scientific or complementary matters, either on the job or in dedicated training sessions. IARC has recently implemented a Fellowship Charter with the aims of providing more structured career development for Fellows and of improving their training experience. The support of COFUND would allow IARC to continue to improve its training activities by allowing a further expansion of the Postdoctoral Fellowship Programme and enhancing the generic training initiatives available at the Agency.";3101408,64;1240563,46;FP7-PEOPLE-2012-COFUND;/MC-COFUND;CENTRE INTERNATIONAL DE RECHERCHE SUR LE CANCER;FR;;;/LIF;1;0;0;1;0;0 89756;230193;INTERARCHIVE;ONG;FP7-IDEAS-ERC;ERC-AG-ID1;FP7;Interred with their bones - linking soil micromorphology and chemistry to unlock the hidden archive of archaeological human burials;2009-04-01;2015-03-31;;It is apparent that soils/sediments immediately associated with buried archaeological human remains contain a valuable unexploited archive of archaeological information with physical and chemical signatures. Thus, excavation of human graves, for cultural reconstruction and to understand archaeological burial practices, aspects of human health and for forensic investigations would benefit significantly from development of a systematic and rigorous scientific approach, allowing maximum information retrieval. We propose a novel framework for sampling and analysis, applying complementary analytical approaches to ongoing burial excavations in 17 sites in Europe, North Africa and Mongolia. We aim to test the combined complementary power of soil micromorphology, inorganic geochemistry and organic chemical analyses to recover cultural and environmental information from historic and archaeological graves, particularly in situations where physical remains can no longer be recognised visually. The analytical techniques will provide information at macro-, micro- and nano-scales, generating complementary data that will enable interpretation of physical remains according to chemical composition (organic and inorganic). The study will enable assessment of preservation potential as a function of soil type and chemistry and permit analysis of fluids movement through the burial environment and their impact on microscopic and chemical signatures. The new interdisciplinary approach that we will develop and validate will provide a protocol for the international archaeological and forensic communities, and sampling schemes for scientific analysis of archaeological/historical burials. The total combination of our results will produce an entirely new richer picture of unseen cultural and biological associations with burials. We expect to deliver a new framework for integrated sampling, analysis and interpretation of grave/burial soils with a comprehensive online searchable database.;2481920,49;2481920,49;ERC-2008-AdG;/ERC-AG;UNIVERSITY OF YORK;UK;;;/SCI;1;0;0;1;0;0 110514;339140;GravQuantMat;ONG;FP7-IDEAS-ERC;ERC-AG-PE2;FP7;Gravity, Black Holes and Strongly Coupled Quantum Matter;2014-03-01;2019-02-28;;"States of matter in which the interactions between the microscopic constituents are both strong and quantum mechanical lie at the frontier of our understanding of nature. Such states appear in a wide variety of settings including high temperature superconductors, gases of cold atoms and the quark- gluon plasma created in the high-energy collisions of nuclei. Understanding the properties of such strongly coupled quantum matter poses huge conceptual challenges because standard perturbative techniques break down at strong coupling. In a remarkable development, the mathematical framework of string theory has provided a fundamentally new way to study strongly coupled quantum field theories using a dual, weakly coupled gravitational description. Furthermore, this duality states that the phase structure of the quantum field at finite temperature is precisely described by black hole geometries. The principal thrust of the proposal is to develop our understanding of these gravitational techniques in order to make contact with real world systems, particularly in condensed matter physics. The proposal focuses on four main topics in this emerging, rapidly developing and interdisciplinary field. The first is to extend our understanding of known strongly coupled quantum critical ground states using gravitational solutions and also to search for new ones. The second is to map out the phase structure of strongly coupled quantum field theories at finite temperature by constructing a wide variety of new black hole solutions. Superconducting and spatially modulated phases will be a particular focus. Thirdly, fermion spectral functions will be calculated to extend our understanding of non-Fermi liquids, which are known to arise in many materials. The fourth topic is to explore the behaviour of strongly coupled systems in situations far from thermal equilibrium by studying the dynamical process of black hole formation.";1963542;1963542;ERC-2013-ADG;/ERC-AG;IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE;UK;;;"/PSE;/SCI";1;0;0;1;0;0 88021;220620;GWAT-LCA;ONG;FP7-PEOPLE;PEOPLE-2007-2-1.IEF;FP7;Revising the Role of Groundwater in Life Cycle Assessment;2008-02-15;2010-02-14;;Life Cycle Assessment (LCA) is the standardised method for assessing the environmental impacts of any product or service. After quantifying all associated emissions and the consumption of resources, this impact is expressed with respect to a few common impact categories. These are supposed to reflect major societal and environmental priorities. Although groundwater is the most extracted raw material in the world, and extraordinarily important for most parts of the EU, it is virtually ignored in LCA. To overcome this deficiency, an interdisciplinary approach is needed. The proposed fellowship integrates a hydrogeologist into a prominent group of LCA experts, in order to develop the initial steps for tackling groundwater quality and quantity issues within an LCA framework. The fellow is offered extensive training on LCA concepts to combine the perspectives of both LCA expert and hydrogeologist. The research work includes a general gradation of threats to groundwater and the development of a competent modelling framework. The latter task is dedicated to the improvement and consistent development of modelling tools. This is to enable a balanced simulation of different hydrogeological threats, and to uniformly account for the spatial variability of environmental conditions. A major focus is placed on the issues of whether, and how, groundwater can be considered a safeguard object within impact assessment, assumed that it represents a separate receptor. The scientific results of this project are expected to be fundamental but still incomplete in achieving a generally valid methodology, which complies with the holistic requirements of LCA practice. However, it will be a necessary starting point for revealing the principal relationships between LCA and hydrogeology and ultimately defining the research needs in this highly timely subject. For the fellow, the profound thematic and social expertise gained will be ideally suited to a novel and ambitious field of science.;178927,59;178927,59;FP7-PEOPLE-2007-2-1-IEF;/MC-IEF;EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH;CH;;;"/SCI;/EDU";1;0;0;1;0;0 102996;302021;QuaCoCoS;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IEF;FP7;Quantum Correlations in Complex Systems;2012-08-01;2014-07-31;;"Quantum correlations in complex systems (QUACOCOS) constitute a key element of modern quantum information theory. This interdisciplinary field combines many concepts and tools from various mathematical and physical areas of research, ranging from complexity theory to quantum mechanics of large systems. Quantum correlations and entanglement are at the heart of many of the possible applications of quantum information theory. They provide the potential for unconditionally secure quantum cryptography and communication, are required for measurement based quantum computation and are involved in most of the famous quantum algorithms outperforming all classical equivalents. Furthermore these correlations are also fundamental to the physics of large and complex systems. Their role in condensed matter systems, such as e.g. phase transitions, is undoubted, in ionization procedures of quantum gases is commonly accepted and their potential involvement in complex biological systems, such as e.g. DNA and light harvesting complexes, is still subject to a controversial debate. This project aims at first developing the mathematical tools required for a thorough analysis of quantum correlations and entanglement in complex systems. These shall then be used to address many open questions in the physics of large complex systems and investigate potential applications thereof in quantum information science. The results are expected to shed light on the actual role entanglement and correlations play in biological systems, condensed matter systems and quantum algorithms.";182666,89;182666,89;FP7-PEOPLE-2011-IEF;/MC-IEF;UNIVERSITAT AUTONOMA DE BARCELONA;ES;UNIVERSITY OF BRISTOL;UK;/SCI;1;0;0;1;0;0 110521;611526;MAGELLAN;ONG;FP7-ICT;ICT-2013.8.1;FP7;a Multimodal Authoring and Gaming Environment for Location-based coLlaborative AdveNtures;2013-10-01;2017-09-30;;Computer games represent a vast economic market, a key driver of technology, and an increasingly powerful medium for a broad range of applications. The latest wave of innovation for computer games is 'mobile' and, more precisely, 'location-based'. These outdoors mobile experiences are radically different from traditional computer games or their mobile equivalent. They focus the players' attention on the real world around them as much as on the digital world of the game, aiming to create a powerful juxtaposition of the two.Although location-based gaming is an industry on the verge of explosive growth, the creation and deployment of such experiences, especially those involving multiple participants, is simply out of reach for the vast majority of creative industries and authors because of the blend of many cutting-edge technologies they require, their hard to master limitations, and the complex gaming concepts they employ.The first objective of MAGELLAN is to deliver an unprecedented authoring environment based on visual authoring principles in order to enable non-programmers, as well as more advanced users, to cost-effectively author and publish multi-participant location-based experiences. The second objective is to deliver a scalable web platform featuring social networking means and supporting the publication, browsing and execution of a massive number of such experiences. Finally, MAGELLAN will produce a series of guides for authors of location-based experiences that will constitute a reference for interested people as well as a foundational document for future research in the field.To achieve this, MAGELLAN will adopt a holistic approach integrating interdisciplinary research involving a complementary group of world-class experts from multiple scientific and technological domains. A user-centred approach will be adopted in order to place end-users, represented by the 5 SMEs partners and the open User Group members, at the heart of the project.
;9937963;6748523;FP7-ICT-2013-10;/CP;EXODUS ANONYMOS ETAIREIA PLIROFORIKIS;EL;"FATDUX SRO;COVENTRY UNIVERSITY;FUNCIONA SOLUCIONES INFORMATICAS SL;TECHNISCHE UNIVERSITAET GRAZ;DIGINEXT;IMMERSION SAS;KREAIT GMBH;ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE;THE MUDLARK PRODUCTION COMPANY LIMITED;I NAFTEMPORIKI PANOS ATHANASIADIS KAI SIA ANONYMOS ETAIREIA;THE UNIVERSITY OF NOTTINGHAM;TECHNISCHE UNIVERSITAET DRESDEN";"CZ;UK;ES;AT;FR;DE;CH;EL";/INF;1;0;0;1;0;0 107860;328285;METFUNDPHYS;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IOF;FP7;Metaphysics of identity, properties, and relations in fundamental physics;2013-09-01;2016-08-31;;This project belongs to the category of philosophical reflection on the metaphysical consequences of contemporary physical theories. The metaphysical problems that are to be considered concern the analysis of the fundamental notions of objects, identity, individuality, and properties. The central question regarding these concepts is whether and how the numerical distinctness of objects can be grounded in the differences in their qualitative properties. In the light of the recent arguments against the validity of the Principle of the Identity of Indiscernibles within the quantum theory of many particles, it is now common to seek the metaphysical grounding of numerical distinctness in the entire relational structures comprising the objects in question. Alternatively, the hypothesis of the primitive character of numerical identity and distinctness is considered. The project will attempt to investigate these metaphysical issues in the context of a broad range of modern physical theories, including non-relativistic quantum mechanics, relativistic quantum field theory, general relativity, and quantum gravity. Particular attention will be paid to the notion of quantum entanglement and its numerous metaphysical consequences regarding the individuality of objects, the intrinsicness of their properties, and the supervenience of whole structures on individual objects and their properties. The hypothesis of ontic structural realism, with its emphasis on the ontological priority of relational structures over their relata, will be put to the test taking into account the recent developments in fundamental physics. This project is an interdisciplinary undertaking, combining a general metaphysical framework with logical and formal tools and concepts derived from fundamental physical theories.;392423;392423;FP7-PEOPLE-2012-IOF;/MC-IOF;UNIVERSITY OF BRISTOL;UK;;;/LIF;1;0;0;1;0;0 110384;611909;KoroiBot;ONG;FP7-ICT;ICT-2013.2.1;FP7;Improving humanoid walking capabilities by human-inspired mathematical models, optimization and learning;2013-10-01;2016-09-30;;"The goal of the KoroiBot project is to enhance the ability of humanoid robots to walk in a dynamic and versatile fashion in the way humans do. Research and innovation work in KoroiBot will mainly target novel motion control methods for existing hardware, but it will also derive optimized design principles for next generation robots.By doing so, KoroiBot addresses the ambitious goals set for the humanoid robots of the 21st century which are supposed to work and replace humans e.g. in households, disaster sites or space missions but which still lack the very fundamental ability to walk in a human-like fashion. Compared to all the intelligence that humanoids have to acquire to perform these tasks, the demand for an improved walking performance seems simple, but it is in fact very challenging, and the motion abilities of contemporary humanoids are still far behind their human role models. Human gaits are at the same time efficient, robust and versatile but gaits of humanoids or bipedal robots are at best good in one of these areas. This problem is not only linked to the present hardware, but also to a large extent to the control principles and the software used.The KoroiBot project will address this problem by developing novel software techniques for increased walking performance and evaluating them on the partners's existing humanoids. To fully demonstrate the capabilities of the software, a prototype design of a new robot will be developed to be exploited by our industrial end users after the end of the project.The new software technologies are based on mathematical models and methods, in particular optimization, and learning from biology, that will help to increase humanoid walking performance. Especially for humanoid robots with their redundant DoF, optimization is the solution to make the redundancy a benefit rather than a burden.The KoroiBot methodology is based on the following pillars:• Investigation of human walking by experiments, extraction, motion primitives mathematical models as well as an identification of walking principles• Development of adequate transfer rules• Development of novel optimization and learning based control approaches for walking for humanoids, assembly of a walking alphabet;• Integration of these techniques on several robots.We study different walking tasks in this project: walking on level ground and uneven terrain, on balance bars and step stone bridges, in interactions with other people, as well as multi-contact walking with additional hand supports and push recovery. This is only possible by a truly interdisciplinary approach combining expertise in humanoid robotics, mathematics, cognitive sciences and biomechanical modeling.Beyond the scope of humanoids, the methods can be useful for the design and control of exoskeletons and intelligent prostheses, in functional electrical stimulation of hemiplegic or paraplegic patients, biped-based novel transportation systems or in computer animations and games.
";5493477;4159999;FP7-ICT-2013-10;/CP;RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG;DE;"WEIZMANN INSTITUTE OF SCIENCE;FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA;KARLSRUHER INSTITUT FUER TECHNOLOGIE;EBERHARD KARLS UNIVERSITAET TUEBINGEN;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;TECHNISCHE UNIVERSITEIT DELFT";"IL;IT;DE;FR;NL";/INF;1;0;0;1;0;0 110180;612273;CLEVER;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IAPP;FP7;Contrast-enhanced uLtrasound for livEr-disease eValuation: development and validation of a novel E-Health-software for Risk-stratification;2013-10-01;2017-09-30;;"The CLEVER project is a 4-years training and transfer of knowledge program between a highly innovative company working in advanced biomedical image processing and two renowned academic groups working in the field of liver diseases and ultrasound research. The scientific and industrial aim of CLEVER is to develop, validate and transfer to clinical practice a novel electronic-health system based on the analysis of liver dynamic contrast-enhanced ultrasound images to assess the severity of derangement of the intrahepatic vascular network in cirrhosis. This feature is closely related with portal hypertension and liver failure, which are the two most important complications of cirrhosis. The outputs of CLEVER will allow an objective prognostic stratification of patients with cirrhosis replacing current invasive and more expensive tools, such as measurement of portal pressure or biopsy. This goal is achievable within the project duration since all participating partners are highly committed: the academic partners are opinion leaders who have already contributed to improve the management of patients with cirrhosis, and will collaborate with an industrial partner who have already provided new e-health tools applied to medical imaging for risk stratification purposes. The project will be structured and developed to exploit at best the interdisciplinary approach, expertise and complementarities between the industrial and academic partners, in order to foster a creative intersectorial collaboration, accomplishment of its scientific aim, and provide high quality training for the participating researchers. This is expected to be of high benefit for their individual career development. CLEVER will permit to transfer the academic knowledge into an e-health product to be implemented in ultrasound equipments and used in clinical practice in hepatology. CLEVER will increase the visibility of UE in the sector of health technology, and will impact positively on UE citizen’s health.";1362743,41;1362743,41;FP7-PEOPLE-2013-IAPP;/MC-IAPP;CONSORCI INSTITUT D'INVESTIGACIONS BIOMEDIQUES AUGUST PI I SUNYER;ES;"EXPERT YMAGING SL;ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA;HOSPITAL CLINIC I PROVINCIAL DE BARCELONA";"ES;IT";/LIF;1;0;0;1;0;0 109607;602646;MultISyn;ONG;FP7-HEALTH;HEALTH.2013.1.2-1;FP7;Multimodal Imaging of rare Synucleinopathies;2013-10-01;2018-09-30;;"Despite remarkable progress in the understanding of the molecular pathogenesis of neurodegenerative diseases (NDD), no causative or disease-modifying treatment is currently available. Aggregation of misfolded proteins are thought to play a crucial role in the pathogenesis, but attempts to exploit this knowledge for novel treatments have not been successful. Also, pathogenetically relevant biomarkers of protein aggregation are lacking. In order to overcome this critical road-block, we have assembled an interdisciplinary consortium, consisting of world-leading experts in structural biology and ligand development, multimodal neuroimaging, animal models and clinical trials to develop a novel imaging system for combined simultaneous molecular and functional imaging (PET-MRI/fMRI) for two rare diseases caused by excessive accumulation of misfolded alpha-synuclein (?SYN), multiple systems atrophy (MSA) and parkinsonism caused by mutations in the alpha-synuclein gene (SNCA), which will serve as proof-of-principle models for the more common and heterogeneous NDD. With this technology we will pioneer the monitoring of protein aggregation as a biomarker for therapeutic effects in the framework of individualized causative treatment. The central aspects of the work-flow including ligand design, software development and drug trials will be driven by three highly specialized SMEs, while translation to animal models and clinical use will be implemented by top academic centers. The groundbreaking progress will include: 1. Establish a multimodal imaging algorithm based on a new PET tracer and embracing structural and functional MRI methods to yield an ?SYN specific tool 2. Test this multimodal, molecular neuroimaging algorithm in animal models with regard to its potential for diagnosis, mirroring the natural disease course and response to therapy 3. Translate the algorithm including the therapeutic modality (i.e. immunotherapy with PD01, NCT01568099) to the clinical setting.";7865514,2;5999998;FP7-HEALTH-2013-INNOVATION-1;/CP-FP;EBERHARD KARLS UNIVERSITAET TUEBINGEN;DE;"AARHUS UNIVERSITET;PMOD TECHNOLOGIES GMBH;IDRYMA IATROVIOLOGIKON EREUNON AKADEMIAS ATHINON;MEDIZINISCHE UNIVERSITAT INNSBRUCK;AFFIRIS AG;LUNDS UNIVERSITET;MODAG GmbH";"DK;CH;EL;AT;SE;DE";/LIF;1;0;0;1;0;0 110659;316309;INERA;ONG;FP7-REGPOT;REGPOT-2012-2013-1;FP7;Research and Innovation Capacity Strengthening of ISSP-BAS in Multifunctional Nanostructures;2013-10-01;2017-03-31;;The Institute of Solid State Physics, part of the Bulgarian Academy of Sciences is the leading Bulgarian Research Institute in the field of solid matter research and its applications into multifunctional nanostructures.The INERA is an important mean for ISSP to rapidly increase its human and technological capacities, to reinforce its local networks and to deepen its partnerships on a European scale. It will mainly consist in an upgrade of equipment, scientific mobility trainings in le?ding EU research centres, life-long trainings, partnership deepening and dissemination activities. INERA aims at preparing ISSP to become a national reference and reliable player on multifunctional planar nanostructures innovation niche employing available research capabilities and seeking EU soundness and visibility. The main expected project outcome for ISSP is to provide a new interdisciplinary view, to establish new links for common research and to encourage future synergies on national and international levels. The project will strengthen the capacity of business exploitation of research results and cooperation with industry and will build a long-term collaboration with research organizations and enterprises from EU. The project will have an important innovation impact as core research activities at ISSP are streamlined towards development of a Tunable Tool NanoMembrane: durable, high permeability, high thermal budget, tunable, scalable and Mass Production Capable Nanomembrane. This is expected to bring a new step in membrane technology development, triggering an avalanche of new products and processes in a wide range of applications including all known membrane industry aspects (separation by organic solvents, global water challenge like wastewater / desalination, fuel cells applications, and the life-health industries) with significant improvement of their energy effectiveness and environment ”shadow print”. INERA is supported by 8 leading EU research and 4 industry partners.;4541368,8;4053611;FP7-REGPOT-2012-2013-1;/CSA-SA;INSTITUTE OF SOLID STATE PHYSICS BULGARIAN ACADEMY OF SCIENCES;BG;;;/SCI;1;0;0;1;0;0 98707;271739;CivLibsID;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-RG;FP7;Rights and Liberties in a Comparative Perspective: A Cross National Analysis of Discrimination Against Sexual Minorities;2011-04-01;2015-03-31;;This interdisciplinary research project will attempt to develop a new theoretical paradigm for the understanding of rights and liberties in a comparative perspective, with a particular emphasis on the rights and liberties of sexual minorities. The innovative aspects of the research are in its attempt to form a new theoretical framework, the collection of original data and the use of a combination of cutting edge methodological approaches to empirically test the theory. The proposed project aims to contribute in several ways to the discipline of political science, the study of law and public law, sociology and to policy studies. This research project’s main goal is to explain the creation of rights and liberties in a comparative perspective by analyzing the systematic effects of variables running the gamut from the origins of the legal system and the nation’s level of globalization to modernization and political inclusion in the polity. In terms of productivity, the ultimate goal is to produce a book manuscript and a series of journal articles based on the novel theory, data and methods. In addition, an international conference will be organized on the topic, where researchers from Europe, Israel and elsewhere will present their work and discuss substantive and methodological issues. Lastly, a student exchange program with institutions in Europe and the United States will be established and additional grant applications will be based on the products of this project.;100000;100000;FP7-PEOPLE-2010-RG;/MC-IRG;TEL AVIV UNIVERSITY;IL;;;/SCI;1;0;0;1;0;0 97273;265286;I-REDD+;ONG;FP7-ENVIRONMENT;ENV.2010.1.1.6-1;FP7;Impacts of Reducing Emissions from Deforestation and Forest Degradation and Enhancing Carbon Stocks;2011-01-01;2014-12-31;http://www.i-redd.eu/;"At COP15 in Copenhagen one outcome was a commitment to develop a mechanism for reducing greenhouse gas emissions from deforestation and forest degradation and enhancing carbon stocks (REDD\). There is, however, only a limited research basis for such a mechanism particularly with regard to the need for understanding and monitoring the impact of REDD\ activities on climate effectiveness, cost efficiency, equity and co-benefits. I-REDD\ will approach these challenges from a truly interdisciplinary perspective. The overall objective will be to obtain an improved understanding of how the implementation of REDD\ mechanisms may 1) reduce emissions of GHG and maintain or enhance existing stocks of carbon in vegetation and soil of various land cover types; 2) impact livelihoods and welfare of local farming communities and differences between communities; 3) impact biodiversity conservation, and 4) provide a realistic framework for monitoring, reporting and verification of REDD\, including the importance of governance and accountability at multiple levels. To complement other research initiatives we propose to work in the uplands of Southeast Asia in the ‘Heart of Borneo’, Kalimantan, Indonesia, and in the northern parts of Lao PDR and Vietnam, and Yunnan in Southwest China. Rapid land use transitions from forest and shifting cultivation to other, more intensive land use systems and widespread forest degradation are occurring in these areas, making the potential for REDD\ particularly pronounced. Moreover, REDD\ may considerably impact on local economies, because of the high population densities in the region. The partners in I-REDD\ are leading research institutions in Europe and Southeast Asia, international research organizations, an NGO and an SME. The consortium has a strong emphasis on local dissemination and capacity development in order to ensure that project results influence REDD\ policy development at local, national and global level.";4287934;3149968,5;FP7-ENV-2010;/CP-FP;KOBENHAVNS UNIVERSITET;DK;"UNIVERSITY OF EAST ANGLIA;INTERNATIONAL CENTRE FOR RESEARCH IN AGROFORESTRY;TRUNG TAM SINH THAI NONG NGHIEP;UNIVERSITAET BERN;KUNMING INSTITUTE OF BOTANY CHINESEACADEMY OF SCIENCES*KIB;WWF INDONESIA;NATIONAL UNIVERSITY OF LAOS;HUMBOLDT-UNIVERSITAET ZU BERLIN;NORDISK FOND FOR MILJ? OG UDVIKLING;INSTITUT DE RECHERCHE POUR LE DEVELOPPEMENT;CENTER FOR INTERNATIONAL FORESTRY RESEARCH;LEIBNIZ-INSTITUT FUER AGRARENTWICKLUNG IN TRANSFORMATIONSOEKONOMIEN (IAMO);THE UNIVERSITY OF EDINBURGH";"UK;KE;VN;CH;CN;ID;LA;DE;DK;FR";"/ENV;/AGR;/CCC";1;0;0;1;0;0 106514;318932;SHARINGSPACE;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IRSES;FP7;intercultural cities and collective space;2012-12-01;2015-11-30;;"SharingSpace. Research on intercultural cities and collective space International migration to cities has become a critical issue in countries of the North as well as of the South affecting all aspects of urban life. Migration is a cross-cutting issue that requires a multiplicity of focuses as well as disciplines and can benefit from comparative analysis. Given that in contemporary globalized cities collective space is where the willingness of society to include or its stance to reject the other becomes manifest, SharingSpace objective is to share the understanding of perceptions, uses and provisions of public space in different EU MSs and TCs. SharingSpace general goal is the creation of a network among research centres focussing on the adequate management of international migration in cities of EU MSs (Venice; Lisbon) and TCs (Buenos Aires, Mexico City, Johannesburg,) as a critical feature of urban policies promoting social cohesion. SharingSpace specific aims are: -to enhance the research skills of researchers -to contribute to the advancement of interdisciplinary studies and comparative research on social and spatial inclusion of international migrants in urban areas. -to strengthen relations among EU MSs and TCs research centres, with the objective of developing further common activities. The Project will overcome barriers among different disciplines that curb the exchange of knowledge and persons in the academic world. The promotion of researchers’ mobility will foster interaction and fusion of different expertise and diverse perspectives for exploring the challenges international migration is posing to urban governance in different contexts. The possibility of publishing scientific articles on the SSIIM Paper Series will contribute to their curriculum development and excellence.";75600;75600;FP7-PEOPLE-2012-IRSES;/MC-IRSES;UNIVERSITA IUAV DI VENEZIA;IT;INSTITUTO DE GEOGRAFIA E ORDENAMENTO DO TERRITORIO DA UNIVERSIDADE DELISBOA;PT;/SCI;1;0;0;1;0;0 96453;255568;CLIMB;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IEF;FP7;Quantifying Uncertainty in Climate Projections including Biogeochemical Feedbacks;2011-05-01;2013-04-30;;State-of-the-art earth system models used for long-term climate projections are becoming ever more complex in terms of not only spatial resolution but also the number of processes included in the models. Biogeochemical processes are just beginning to be incorporated into these complex models due to a difficulty in resolving heterogeneous biogeochemical processes. The motivation of this project is to quantify how climate projections are influenced by additional biogeochemical feedbacks that have not yet been taken into account in contemporary climate models. The researcher proposes an approach to look into coupled carbon-nitrogen-phosphorus-sulfur (C-N-P-S) cycle processes together with first-order physical processes. Biogeochemical studies show that C-N-P-S cycles are intimately interlinked via biosphere, resulting in an amplification of carbon cycle feedbacks. The proposed study will treat rivers and the global coastal zone explicitly, which are known to be essential for global biogeochemical cycle but are not represented in today’s earth system models. Uncertain parameters in the model will be constrained by an inverse estimation approach using various geophysical observations during the past millennium. The project addresses the following two questions: - Do coupled C-N-P-S biogeochemical cycles reduce the uncertainty in the past and present global carbon budget? - How much do coupled C-N-P-S cycle feedbacks contribute to the future global warming? How do they affect uncertainties? The interdisciplinary study will not only have a profound implication for future climate projections but also provide a new insight into outstanding research questions that cannot be answered in individual fields alone. Our research will serve as a pilot study to inform the climate research community as to whether coupled C-N-P-S cycle processes are important to be included in next-generation climate models.;165865,2;165865,2;FP7-PEOPLE-2009-IEF;/MC-IEF;EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH;CH;;;"/SCI;/EDU;/ITT";1;0;0;1;0;0 94431;249194;RESPPIS;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-RG;FP7;Relationships between Energetic Status and Population Parameters in Seals;;;;In light of global climate change, reliable tools to assess status and trends of animal populations are essential to support efficient species conservation management. This project is aimed at identifying the impact of environmental changes on population dynamics of top marine predators by studying how fish availability affects fitness and survival of seals in the North Sea. We will first determine how changes in fish availability affect bioenergetics and foraging behaviour of seals through controlled laboratory experiments on captive seals mimicking different environmental and food conditions. Using these data, a dynamic bioenergetic model will be built to determine energy budgets in relation to foraging, age/size class, season and prey availability variables. We will then estimate how this translates into changes in fitness, survival and reproduction in seal populations based on foraging behaviour of wild seals recorded using telemetry equipment. From these, a state-space model will be developed to estimate age, fecundity, and juvenile survival rates as functions of differences between energy requirements and intakes and of environmental parameters. Finally, we forecast future population trends as well as potentially times and places where seals might be most sensitive to environmental changes. This will be done by linking the previously mentioned state-space model to environmental conditions and prey distribution predictions to estimate spatial and temporal location profitability and seal survival. This interdisciplinary approach will combine laboratory experiments, tracking data from free-ranging seals and complex state-space and spatio-temporal model analyses. It will contribute to advancement in marine mammal ecology by providing essential physiological and behavioural baselines for seals. Ultimately, this will help maintain conservation and sustainable management of habitats and species as per EU Habitat Directives.;100000;100000;FP7-PEOPLE-2009-RG;/MC-IRG;THE UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS;UK;;;/SCI;1;0;0;1;0;0 105263;313339;THESIS;ONG;FP7-IDEAS-ERC;ERC-SG-SH6;FP7;Theology, Education, Scholastic Institution and Scholars-network: dialogues between the University of Paris and the new Universities from Central and Eastern Europe during the Late;2012-10-01;2018-07-31;;"The THESIS project proposes a pioneering study of a coherent corpus of medieval manuscripts consisting of all the commentaries on the Sentences composed in Paris and in the new universities from Central Europe between 1350-1450. A Sentences commentary is a core component of the medieval academic curriculum, a collection of theses that scholars had to defend in the universities in order to obtain the title of master or doctor of theology; it is actually the unique equivalent of our modern PhD thesis. This investigation aims to provide new information concerning the intellectual atmosphere inside the European universities in an attempt to respond to various historical questions: How do the Sentences commentaries of this period lead to the formation of a European university identity? Who are the masters of the time? What is the importance of a Sentences commentary (the modern PhD) in the development of a individual intellectual career during the late Middle Ages? What are the relations and exchanges between the University of Paris and the new universities of Central Europe? Which are the commentaries acquired (by purchase and thus at the request of the readers) in the university libraries of this epoch and in this area of Europe? What are the cultural exchanges between secular masters, monks and friars? How do the religious orders constitute an important factor in the formation of a network for the transfer of knowledge in the universities? Research in the archives (mainly little known ones from Eastern Europe), the study of the manuscripts, the digital edition of the texts and the development of new IT tools for our field will be key components of our project, contributing to a better understanding of a hidden part of European intellectual history. Our project is built upon a strategy promoting erudition (codicology, palaeography, textual criticism), an interdisciplinary scientific approach, and exchange and dialogue between scholars from Western and Eastern Europe.";1494784;1494784;ERC-2012-StG_20111124;/ERC-SG;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FR;UNIVERSITY OF CYPRUS;CY;"/SCI;/SOC";1;0;0;1;0;0 104664;321642;PLATFORM2NANO;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-CIG;FP7;Development of a microfluidic platform to produce nanomaterials and assessment on new nanotechnology applications;2012-10-01;2016-09-30;;"Chemically synthesized nanomaterials (NMts) are being considered as the active elements in many applications, including, photonics, catalysis, energy, medical diagnosis and treatments. In order to achieve the promise of these applications, it will be critical to have an efficient, reproducible synthesis technique to produce the NMts. Currently, nanoparticles are synthesized in a batch mode in small volumes, which is suffering from irreproducibility and lack of NMts quality from batch to batch. Furthermore there are challenges in scaling batch procedures up to quantities needed for application development. Consequently, a new technological approach is required to assure nanotechnology feasibility. This project takes as a goal the development of multi-functional platforms based on microfluidics (MF) to address the wet-chemistry weaknesses and restrictions of small-scale batch reactors. Basically, MF allow an exquisite control on synthesis variables. The superior reaction control in a microliter or even nanoliter volume, enable to nanoengineer NMts in a continuous production process, addressing some issues such as scaling up and reproducibility. Additionally, MF promote some valuable advantages, including enhancement of mass and heat transfer, feedback control of temperature and feed streams, safer operational environment and potential for sensor integration. A variety of MF approaches will be developed to fine tune the NMts: sequential addition, slug flow, microwave and ultrasound irradiation. Since the applicant is a member of the highly-interdisciplinary Aragon Institute of Nanoscience, several collaborations with researchers from other areas have already been established. This enables the NMts obtained from this emerging technology to be employed in applications related not only to catalysis, which is the applicant´s main field of activity, but also in other areas such as nanocomposites and nanomedicine, where nanoparticles play a key role.";100000;100000;FP7-PEOPLE-2012-CIG;/MC-CIG;UNIVERSIDAD DE ZARAGOZA;ES;;;/LIF;1;0;0;1;0;0 104568;306605;HOLOLHC;ONG;FP7-IDEAS-ERC;ERC-SG-PE2;FP7;Holography for the LHC era;2012-10-01;2017-09-30;;"With the advent of the Large Hadron Collider (LHC), particle and nuclear physics have entered a new era. Heavy ion collisions at the LHC have already begun to provide new insights into the quark-gluon plasma (QGP) phase of Quantum Chromodynamics (QCD). The beam energy scan program at the Relativistic Heavy Ion Collider (RHIC) will explore part of the rich phase diagram of QCD at finite baryon density. Proton-proton collisions at the LHC will uncover the mechanism responsible for electroweak symmetry breaking (EWSB). Much of the physics involved in these experiments is, or may turn out to be, strongly coupled. Making contact with experiment thus requires a theoretical understanding of strongly coupled gauge dynamics. This project aims at using the gauge/string duality to make essential contributions to our understanding of: (i) Out-of-equilbrium dynamics of the QGP, in particular of the thermalization process; (ii) The QCD phase diagram, in particular of color superconducting phases; (iii) Strongly coupled dynamics potentially relevant for EWSB, in particular of walking dynamics. These three main objectives are interconnected by two horizontal lines: (i) Identification of universal observables, which hold the best potential to make contact with experiment, and (ii) Communication with other fields, which is crucial for the success of such an interdisciplinary proposal.";1419424;1419424;ERC-2012-StG_20111012;/ERC-SG;UNIVERSITAT DE BARCELONA;ES;;;"/PSE;/SCI";1;0;0;1;0;0 96355;259432;MULTIBIOPHOT;ONG;FP7-IDEAS-ERC;ERC-SG-PE4;FP7;Multiphoton processes using plasmonics towards advanced nanobiophotonics;2011-01-01;2015-12-31;;"Proposal summary Biophotonics is an emerging interdisciplinary field. Modern laser spectroscopic methods in combination with microscopy open up exciting new ways to study biological objects. For biological applications, multi-photon or non-linear spectroscopy can offer several advantages over one-photon excitation. The aim of this project is to explore novel spectroscopic strategies based on multi-photon excitation. In order to overcome lowsignal problems related to multi-photon spectroscopy, we will exploit plasmonics and perform multi-photon spectroscopy in the enhanced local optical fields of gold- and silver nanostructures. I propose a combination of three different plasmonics-enhanced two-photon spectroscopic methods for multimodal two-photon sensing and imaging. This combination can provide information on morphological structures and function of biological systems along with chemical information about molecular composition, structure, and interactions. A key aspect of this new concept will be the implementation of spectroscopically multifunctional nanosensors with plasmonic nanoparticles as basic building blocks. Following multi-photon excitation, these sensors deliver information on their environment inferred from a set of multiple surface-enhanced spectroscopic signatures. The proposed research will generate fundamental knowledge about multi-photon driven processes in enhanced local optical fields and about multi-photon interaction of light and biological matter. This might open up entirely new directions to advance nanobiophotonics. In particular, the outcome of the research will stimulate the new field of two-photon sensing and imaging, which has the capability to advance our understanding of biological systems and processes. The project is expected to have broad impact and contribute to the development of multi-photon optical sensing and multi-photon excited photophysics and photochemistry with applications in physics, chemistry, energy technology, biotechnology and medicine.";1394679;1394679;ERC-2010-StG_20091028;/ERC-SG;HUMBOLDT-UNIVERSITAET ZU BERLIN;DE;;;"/PSE;/MAT";1;0;0;1;0;0 89381;230118;IREGIONS;ONG;FP7-REGIONS;REGIONS-2008-1-01;FP7;Internet-based and mobile technologies for regions in the net economy;2009-01-01;2011-12-31;http://www.iregions.de/;"An increasing use of the Internet worldwide and its penetration to virtually all spheres of life leads to a new form of society and of economy: the Net Society and Net Economy. New needs and challenges have emerged for research, business and industry: To be effective and to produce applicable results, research has to be tested, at least as a proof-of concept, in large scale environments. The increasing complexity of the innovation process requires a closer interaction between research and business. Businesses need to constantly adapt their products, skills and business models; they need therefore different partners and experts from diverse fields, able to work in interdisciplinary fields. New mobile technologies can overcome the digital divide and increase cultural, social and political participation and understanding. However, security and privacy issues need to be carefully handled due to potential deployment for surveillance and control purposes. The iRegions proposal addresses those challenges by providing a strategy aiming at maximising the benefits of research infrastructures for regional economic development within the following ICT-based clusters: • CyberForum (Germany) • Kista Science City (Sweden) • Tartu Science Park (Estonia) The concept relies on following cornerstones: • Living Labs will enable the iRegions to become pilot regions for the creation of new ser-vices, technologies and business models of the Net economy. A tight networking will allow strengthening the innovative capacity and efficiency of all involved parties • Leading edge projects will lead to the development of pioneering innovations and the creation of new markets. • Ecosystems for growth will favour strong interaction between research, business and local authorities for the benefit of companies’ growth and economic development. iRegions will deliver a Joint Action Plan for the implementation at regional and inter-regional level of the solutions newly designed by the partners";1115433,03;954883,69;FP7-REGIONS-2008-1;/CSA-SA;CYBERFORUM EV;DE;"Stiftelsen Elektronikcentrum i Kista;BALTIC INNOVATION AGENCY OÜ";"SE;EE";"/ECO;/REG";1;0;0;1;0;0 102017;289880;REPRO-TRAIN;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-ITN;FP7;Reproductive Biology Early Research Training;2012-01-01;2015-12-31;;"The “Reproductive Biology Early Research Training” network (REPRO-TRAIN) aims to provide all the elements required to train the next generation of researchers with the latest skills to solve the current societal problems in male reproductive biology (Andrology). The decline in sperm counts and concomitant increase in testicular cancer demands research in this field as an urgent priority. Spermatogenesis is the essential physiological process for male gamete production. It also provides a ideal paradigm model system to study cellular development and differentiation; necessary for an understanding of dysfunction. An innovative aspect of this ITN is to harness Systems biology into Reproductive Science. Here, we offer a high calibre, multidisciplinary research environment involving frontier “omic” approaches in male reproductive biology for the first time with the aim of identifying the gene networks that are deregulated in the infertile testis. The REPRO-TRAIN programme will integrate this highly interdisciplinary training with knowledge transfer to strategic stakeholders. We will include universities and research institutes with internationally recognized experience in postgraduate training, hospitals recognized for high quality clinical training and key private companies. This trans-national, inter-disciplinary research network will provide a robust platform for the success of the proposed ITN. Ten ESR and four ER researchers will perform studies in genetics and epigenetics, molecular male reproductive medicine, molecular and structural biology, and biotechnology with hands-on training in cutting-edge technologies relevant to current molecular-genetic and medical research. A clear definition of their Personnel Career Development Plans, training in complementary skills allied to business and the coordination between the elements that compose this plan are detailed herein.";3649828;3649828;FP7-PEOPLE-2011-ITN;/MC-ITN;CONSORCI INSTITUT D'INVESTIGACIONS BIOMEDIQUES AUGUST PI I SUNYER;ES;"PHILIPPS UNIVERSITAET MARBURG;INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE;UNIVERSITA DEGLI STUDI DI FIRENZE;UNIVERSITY OF LEEDS;THE QUEEN'S UNIVERSITY OF BELFAST;ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM;ORYZON GENOMICS SA";"DE;FR;IT;UK;NL;ES";"/LIF;/SCI";1;0;0;1;0;0 105010;317058;BacTory;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-ITN;FP7;"Biorefinery Training Platform: Bacterial Factories for Sustainable Chemical and Drug Production";2012-10-01;2016-09-30;;There is a growing demand for scientific, technological and industrial developments, which can support the transition from oil based chemical refinery towards biorefinery processes. The Training Program of this IDP – BacTory – comprises a multi-disciplinary platform providing scientific and industrially relevant skills necessary for establishment of next-generation biorefinery activities in Europe. The program is designed to integrate state-of-the-art research in relevant areas associated with future biochemical production scenarios with corresponding industrial activities and production plans. The objective is to train some of the most talented European young scientists (ESR) to become future leading scientists, technologists and entrepreneurs, who can take on leadership in the required scientific and technological development of next-generation industrial biorefinery applications. The scientific program comprises specific research activities in three relevant and essential areas: 1) Discovery of novel biosynthesis pathways for important chemicals, 2) genetic and metabolic engineering for designing microbial cell factories, and 3) development of novel production systems based on complex microbial population structure and surface associated communities. The individual ESR projects will be defined in close collaboration with industrial partners to ensure the industrial relevance of the research activities. The Training Program will further comprise participation in course activities aiming at expanding the scientific know-how and skills of the ESRs as well as their awareness of business options, e.g. through a unique novel program for interdisciplinary training of scientists and business people in the commercialization of biotechnology. BacTory is placed in a unique strategic research center – the Novo Nordisk Foundation Center for Sustainability (DTU Biosustain) – which has as a major goal to carry out world leading research directed towards industrial applications;4069870,33;4069870,33;FP7-PEOPLE-2012-ITN;/MC-ITN;DANMARKS TEKNISKE UNIVERSITET;DK;;;/LIF;1;0;0;1;0;0 104890;314031;OPTIRAIL;ONG;FP7-TRANSPORT;SST.2012.5.2-2.;FP7;DEVELOPMENT OF A SMART FRAMEWORK BASED ON KNOWLEDGE TO SUPPORT INFRASTRUCTURE MAINTENANCE DECISIONS IN RAILWAY CORRIDORS;2012-10-01;2015-09-30;;"'In a context of wide use of transport, it is necessary to increase efficiency of the different transport modes as well as their interaction. To that effect, rail transport will play an important role in the future by increasing its capacity. Thus, it would be necessary to strength the competitiveness of railway ensuring a sustainable, efficient and safe service. In that sense, it is essential to improve the interoperability and safety of national networks in order to promote a single European Rail Market. Nevertheless, there are still several barriers to overcome as a consequence of the lack of a common definition of standards at European level. Within this framework, the main objective targeted by the OPTIRAIL project aims at developing a new tool, based on Fuzzy and Computational Intelligence techniques and validated through two case studies, that will enable the better cross-border coordination for decision making of railway infrastructure maintenance across the European railway corridors. In order to be able to achieve the exposed objective, the project Consortium is comprised of a well-balanced group of 9 partners from 6 European countries with complementary skills and expertise, including all the necessary profiles to deal with the scheduled project work plan. Furthermore, non-participant railway administrators have shown their interest and commitment to the project. This interdisciplinary group of the railway managers, railway suppliers, software & embedded systems developers, and technological R&D centres are strongly committed to efficiently coordinate their resources over the 36 months duration of the project in order to be able to reach all expected project outcomes. The estimated overall budget of the project is 3.916.343,40 €.'";3916343,4;2700000;FP7-SST-2012-RTD-1;/CP-FP;VIAS Y CONSTRUCCIONES SA;ES;"LULEA TEKNISKA UNIVERSITET;EVOLEO TECHNOLOGIES LDA;STIFTELSEN SINTEF;UNIVERSIDAD DE GRANADA;OSTFALIA HOCHSCHULE FUR ANGEWANDTE WISSENSCHAFTEN FACHHOCHSCHULE BRAUNSCHWEIG WOLFENBUTTEL;MER MEC SPA;FUNDACION CARTIF;ADMINISTRADOR DE INFRAESTRUCTURAS FERROVIARIAS";"SE;PT;NO;ES;DE;IT";/SCI;1;0;0;1;0;0 106344;600709;COFET;CLO;FP7-ICT;ICT-2011.9.12;FP7;Conferences for the Future of FET;2012-11-01;2014-07-31;;"COFET aims at supporting the future development of the FET programme based on a focused dialogue between science, policy, industry, and society. FET Future will realize a set of conferences and workshops addressing current and forthcoming challenges for interdisciplinary, ICT-related visionary research as exemplified in the FET programme of the EU's Framework Programme.
COFET aims to address challenges such as the relation of FET research to innovation and competitiveness; the question of reaching out to a broad public; but also cooperation with the Member States in Horizon 2020.
The project will support a minimum of three conferences with preceding workshops addressing these topics in a complementary fashion with different emphasis given to target stakeholders such as researchers in ICT and other fields, research policy makers, EC officials, industry and innovators, young scientists and students.
COFET particularly aims at impacting on national and European research policy decision makers to secure their support in the form of policies, programmes, instruments and funding. It will assist the design of the future of FET to continue and further expand its success from FP5 to Horizon 2020.
COFET will build on previous knowledge acquired in extensive studies and projects. The FET Future team includes ICT research strategists, experienced conference organisers, RTD policy makers and communication experts. FET Future activities will help to reach out to broad audiences while at the same time sharpening the profile as required for the changing role of FET in the future of EU level future and emerging technology research.
";354505;320000;FP7-ICT-2011-9;/CSA;EUTEMA GMBH;AT;"YOURIS.COM;Eutema Technology Management GmbH & Co KG;MATIMOP - THE ISRAELI CENTER FOR R&D;OPTIMAT LIMITED";"BE;AT;IL;UK";/LIF;1;0;0;1;0;0 104933;306576;QIOS;ONG;FP7-IDEAS-ERC;ERC-SG-PE2;FP7;Quantum Interfaces and Open Systems;2012-10-01;2017-09-30;;"'Researchers have strived to obtain control of a variety of different quantum systems, each characterized by their own distinct advantages: quantum optical systems offer excellent isolation from the environment while solid state systems allow for integrated micro-fabricated devices. At the same time nuclear spins in molecules can remain decoupled from the environment even under rather harsh conditions, and this is the basis of NMR experiments. Given these distinct advantages it is very fruitful to investigate hybrid devices merging the advantages of each of the systems. To do this it is essential to develop quantum interfaces to connect the different systems. By their very nature such quantum interfaces exchange information with their environment and are therefore open quantum systems. In this project I wish to establish a strong theoretical quantum optics group which can guide and inspire the experiments towards breaking new grounds for open quantum systems and making quantum interfaces between distinct physical systems. The objective is to develop concrete proposals for how to experimentally control and exploit the interaction of quantum systems with their surroundings and for how this can be used for quantum interfaces. The work in this project is particularly relevant for applications in quantum information processing, where the current challenge is to take the field from proof-of-principle demonstrations to truly scalable devices. Such challenge demands new interdisciplinary theoretical ideas for hybrid devices. This proposal addresses several key challenges for quantum information processing: scalable multimode quantum repeaters based on hybrid approaches, entanglement enabled quantum metrology, photonic engineering based on surface plasmons, dissipative preparation of entangled states, and phonon engineering for quantum dots. In addition applications towards nuclear spin cooling to improve NMR experiments as well as ultra cold atoms will be explored.'";1431541,8;1431541,8;ERC-2012-StG_20111012;/ERC-SG;KOBENHAVNS UNIVERSITET;DK;;;"/PSE;/SCI";1;0;0;1;0;0 96499;253119;FLUENT;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IEF;FP7;Flavour, unifications and experimental tests;2010-10-15;2012-10-14;;"The flavour structure of matter remains one of the deepest challenges to our current understanding of the elementary particles and their interactions. Indeed, even after more than half century of intense research the flavour patterns underlying most of the high-energy physics processes defies our comprehension. The Standard Model of particle physics, the best description of the sub-nuclear world ever conceived, does not provide any clues to why we observe just three families of quarks and leptons, what is the origin of the peculiar pattern of their quantum-mechanical mixing or why their masses range over more than twelve orders of magnitude. With the advent of the next generation of particle physics experiments, in particular the Large Hadron Collider, the high-precision neutrino facilities, large-volume rare decay searches and other kinds of instruments and techniques focusing on uncovering physics beyond the Standard Model, there is a growing and well-founded expectation that the next decade could witness the first glimpse on these mysteries. The current proposal addresses these fundamental problems from the perspective of Grand Unification, one of the best motivated hypotheses about the nature of the fundamental dynamics governing the very birth of the Universe. A thorough understanding of the elusive low-energy imprints of physics at very high energies provides a unique strategy for testing the unification paradigm, complementing the traditional techniques of its experimental scrutiny. Apart from unwinding further the conundrum of the perennial problem of flavour, the proposed programme stresses the interdisciplinarity, covering topics from astroparticle physics and cosmology up to the experimental signatures and collider phenomenology. In this respect, it has a very strong potential to extend significantly the fellow's research profile, bringing him to the level of a full professional maturity.";205854;205854;FP7-PEOPLE-2009-IEF;/MC-IEF;UNIVERSITAT DE VALENCIA;ES;;;"/SCI;/EDU;/ITT";1;0;0;1;0;0 104763;291783;COFUND-CERN-2011;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-COFUND;FP7;COFUNDing of the CERN Fellowship Programme 2011;2012-10-01;2017-09-30;;"For many years, CERN has operated a trans-national Fellowship programme, offering scientists and engineers challenging opportunities in particle physics research, and in related fields of physics and technology. CERN secured COFUND grants in 2008 and 2010. They offer CERN a timely opportunity to enhance the mobility element of this programme without nationality limitations. The 2011 Call comes at a time when the startup of the Large Hadron Collider has made CERN one of the most exciting places to work for the global physics and technology community. Applicants will propose their own research projects. Selection will be based on the scientific potential of the proposal, and on the demonstrated excellence of the candidate. Working on frontier research and technology projects and profiting from the unique facilities available at CERN, the co-funded Fellows will deepen their knowledge in their own field and acquire international visibility and reputation. They will broaden their skills using the numerous training opportunities and through their exposure to an interdisciplinary and multi-national environment. Inter-sectorial skills will be fostered through CERN’s industrial collaborations and technology transfer projects. Employment conditions will be improved by offering three-year appointments rather than the standard two-year terms of CERN Fellows. At least two of these three years will be spent at CERN. We consider this provision to be justified by the size of the Laboratory, the diversity of the research and training opportunities, and by the uniqueness of CERN’s facilities. However, mobility will be enhanced through the opportunity to spend up to one third of the Fellowship in external institutions, including industrial laboratories. These improvements, enabled by the COFUND action, will further increase the competitiveness of CERN’s Fellowship Programme.";24999245,7;9999698,28;FP7-PEOPLE-2011-COFUND;/MC-COFUND;EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH;CH;;;/SCI;1;0;0;1;0;0 95416;254125;D1SCO-FIL;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IEF;FP7;Disentanglement of the 1D electronic properties of Single-Walled Carbon Nanotubes via separation, co-doping and filling;2010-07-15;2013-09-23;;This project comprises a combined theoretical and experimental approach to engineer substitutionally doped and metallicity separated single walled carbon nanotubes with novel fillings with tailored electronic and optical properties. It aims at significantly advancing the limits of current capabilities that employ functionalized nanotubes with an option to underpin the research field in a short timescale. These predicted and engineered 1D structures act simultaneously as primed bulk n- or p- type material as host for novel fillings (fullerenes, metallocenes, and rare earth compounds) yielding also novel hybrid structures of a metallic core and a semiconducting host. The ultimate goal is a disentanglement of the interplay between charge transfer and hybridizations and bonding environment gaining sound information on the correlated 1D electronic and optical properties with unprecedented level using both the encaged compounds and heteroatoms as tracers. Optical, Raman and high energy spectroscopies and contemporary ab-initio theoretical spectroscopy will be used as a key to analyse these tailor made modifications and the influence of doping, and chemical interactions on the ground and excited state and the electronic transport properties. The final outcome will give a detailed assessment of the application potential in nanooptics and nanomechanics. This project has a highly interdisciplinary nature relying on three different research areas, based on the outstanding candidate’s experience in heteronanotubes, the worldwide renowned spectroscopic expertise of the host and the world-class expertise in theoretical spectroscopy of the training cooperation partner. This project will allow the candidate to strengthen a well established intra-european collaboration and to greatly broaden her scientific background, making of her one of the most highly recognized scientist in her field. This will boost her career to the next scientific level.;166622,8;166622,8;FP7-PEOPLE-2009-IEF;/MC-IEF;UNIVERSITAT WIEN;AT;;;"/SCI;/EDU;/ITT";1;0;0;1;0;0 101083;275289;GENMARPHYTO;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-IOF;FP7;FUNCTIONAL GENOMICS STUDIES IN MARINE PRIMARY PRODUCTIVITY: ENVIRONMENTAL AND POLUTION EFFECTS ON PHYTOPLANKTON;2012-09-01;2015-08-31;;"One of the most serious challenges for humankind this century will be to understand how climate change (past, present and future) influences life in the oceans. It is known that marine phytoplankton carry out almost half of the global net photosynthesis of the planet. Therefore it will be essential to determine how climate change alters microbial metabolism. However, the integration of cell biology and genomics into oceanographic research is not sufficiently developed, even though biological (and especially microbiological) processes are fundamental for maintaining a functional biosphere. This project addresses the application of a novel molecular approach using genomics and metagenomics to elucidate metabolic activities under different conditions in the ocean in various groups of photosynthetic prokaryotes and eukaryotes. These techniques will also allow the rapid identification of candidate genes and facilitate the association of genes with specific metabolic and regulatory functions in different organisms spanning hundreds of millions of years of evolution. The initial phase of the project will investigate unicellular cyanobacteria using full genome microarrays analysis (outgoing). In a second phase, genomics studies will be done in diatoms, unicellular eukaryotes (return). The novelty of the proposed research lies in its interdisciplinary approach linking oceanography with cell biology and genomics. A key novel aspect of the proposal is the application of a comparative approach to very different groups of photosynthetic organisms, which will allow us to contrast the strategies of responses to environmental changes between them. This will improve our knowledge of the crucial roles marine microorganisms play in maintaining the well being of our planet. The successful implementation of the project will result in a substantial transfer of expertise from a world wide-leading centre in marine biology to the applicant and his team on return to a European institute.";332702,5;332702,5;FP7-PEOPLE-2010-IOF;/MC-IOF;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FR;;;"/EMP;/SOC;/COO";1;0;0;1;0;0 104916;303728;NBHCHOICE;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-CIG;FP7;Neighbourhood choice, neighbourhood sorting, and neighbourhood effects;2012-09-01;2016-11-30;;There is a strong belief among academics and policy makers that living in deprived neighbourhoods has a negative effect on residents’ life chances over and above the effect of their individual characteristics: so-called neighbourhood effects. The concept of neighbourhood effects – as an independent residential and social environment effect on individual outcomes – is academically intriguing, but has also been embraced by policy makers, mainly in connection with unemployment and a lack of social mobility. The neighbourhood effects discourse has had a major impact on urban and neighbourhood policies and has influenced governments to spend large sums of money on area based policies. A small but growing critical literature, questions the evidence base of neighbourhood effects. Although it is likely that neighbourhood effects exist, we do not know enough about the causal mechanisms which produce them, their relative importance compared to individual characteristics such as education, and under which circumstances and where these effects are important. This interdisciplinary and international proposal argues that in order to further our understanding of neighbourhood effects, and to provide a solid and sophisticated evidence base for policies aimed at deconcentrating poverty, we should investigate the effects of selection mechanisms into and out of neighbourhoods. NBHCHOICE has three objectives 1) to further develop the theoretical framework linking neighbourhood choice and neighbourhood effects 2) to empirically investigate neighbourhood choice over the life course, and 3) to integrate models of neighbourhood choice with models of neighbourhood effects. The project will use large longitudinal datasets from The Netherlands, UK and Sweden and will bring together researchers from various countries. NBHCHOICE will contribute to the development of theory, to more targeted and effective policy measures, to the career development of the applicant, and to the host institute.;100000;100000;FP7-PEOPLE-2011-CIG;/MC-CIG;TECHNISCHE UNIVERSITEIT DELFT;NL;;;/SCI;1;0;0;1;0;0 92857;243296;TRANSLATIONMACHINERY;ONG;FP7-IDEAS-ERC;ERC-SG-LS1;FP7;Integrative structure and function study of the bacterial and human protein synthesis machinery;2009-12-01;2014-11-30;;The aim of the project is to understand key steps in the molecular mechanisms of protein synthesis across species. The structure and function of pro- and eukaryotic (including human) ribosomes, those cellular nano-machineries that catalyse the decoding of genes, will be studied through an integrative, interdisciplinary structural biology approach. Since in the cell the ribosome is regulated by transiently binding protein and RNA factors, we plan the reconstitution and structural investigation of ribosome complexes in functionally defined states with regulatory proteins and messenger RNAs (mRNA). Four work packages will form the basis of the investigation, (i) the role of mRNA structure in gene expression in pro- and eukaryotes, (ii) the mechanism of translation initiation in prokaryotes as important antibiotic targets, (iii) the high-resolution structure of the human ribosome, and (iv) the architecture of eukaryotic polysomes, the functional protein synthesis entities of living cells. The complexes will be studied using a comprehensive approach which will incorporate biochemistry, structural biology, biophysics and bio-informatics, with cryo-electron microscopy and X-ray crystallography forming the core. The dynamic aspects of the protein synthesis machinery such as structural and functional transitions will be investigated by separation of multiple states through advanced image processing procedures, molecular dynamics simulations and by exploring new developments in optical imaging. Collaborations with leading laboratories have been set up in order to create an efficient framework for which the host institute provides an outstanding infrastructure. The project will provide fundamental knowledge on the mechanism of gene expression regulation at the level of protein synthesis contributing in the long term to the development of new drugs.;1690000;1690000;ERC-2009-StG;/ERC-SG;CENTRE EUROPEEN DE RECHERCHE EN BIOLOGIE ET MEDECINE;FR;;;"/BIO;/LIF";1;0;0;1;0;0 95573;255109;EPISYSBIOL;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IEF;FP7;Epigenetic regulation of the adaptative response of C.reinhardtii to development and environmental stresses:Characterization of .Histone PTMS,gene regulation and pathways employing a Systems Biology;2010-08-10;2012-08-09;;Reversible modifications of DNA sequence and histones serve as a fast and accurate process to regulate gene expression. These mechanisms act specifically and co-ordinately, constituting what is called the epigenetic code, and influence a multitude of cellular processes including, besides the regulation of the transcription, differentiation, DNA replication, repair or imprinting, among others. Aided by the use of multidisciplinary combination of new technologies such as epigenomics, transcriptomics, proteomics, metabolomics and bioinformatics “EpiSysBiol” is expected to precisely identify the epigenetic changes and the variations in the proteome and metabolome that may regulate upon stress conditions and developmental processes in Chlamydomonas. Growth and stress processes mediate the formation of lipidic bodies and biomass in this specie, considered to be the third generation biofuel productor and CO2 trap. Research and training in –omics technologies are expected to stimulate European competitiveness in resolution of epigenetics and systems biology with significant scientific impacts and will help the implementation of Chlamydomonas in European climate change prevention strategies. Therefore “EpiSysBiol” is introducing EU prioritary research directions and topics, to improve the quality of European research in molecular and systems biology, to provide advanced expertise in epigenomics and to carry out interdisciplinary technical developments important not only for plant sciences but also for life sciences and for entire society.;163622,8;163622,8;FP7-PEOPLE-2009-IEF;/MC-IEF;UNIVERSITAT WIEN;AT;;;"/SCI;/EDU;/ITT";1;0;0;1;0;0 104316;322185;RETIF;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-CIG;FP7;Role of enzyme-coupled TRP channels in immune cell function;2012-08-01;2016-07-31;;Low systemic magnesium (Mg2\) levels exacerbate pro-inflammatory diseases, suggesting a putative role of Mg2\ transport in immune system homeostasis. The Mg2\ and calcium (Ca2\) conducting transient receptor potential ion channel, TRPM7 has an indispensable, vital role in cellular physiology. TRPM7 regulates cellular and systemic Mg2\ homeostasis and is essential for immune cell differentiation, proliferation and survival. However, little is known about underlying mechanisms or the physiologic regulation of the protein’s channel or enzymatic domain. Autoimmune diseases are often accompanied by low systemic Mg2\ concentrations, which might be associated with altered TRPM7 function. Thus, it is important to identify whether TRPM7 represents a valuable new target for immune therapy. Antigen-presenting cells (APC) and T cells are pivotal regulators of immune system homeostasis. The intrinsic risk of potentially harmful autoreactive T cells is controlled centrally during selection in the thymus. Peripheral mechanisms to limit autoimmunity include immunosuppression through regulatory T cells (Tregs). In the last years Tregs received enormous attention as their deficiency provokes severe autoimmune disorders. The regulation of tissue homeostasis by APC is equally important to avoid unbalanced pro-reactive immune system responses. APC maintain tissue homeostasis via phagocytosis of invading pathogens and secretion of pro- and anti-inflammatory mediators. In this project we are planning an interdisciplinary approach combining biophysics with basic immunology to study the role of TRPM7 in APC and T cell function and in immune system homeostasis. We are going to use novel innovative tools to identify the physiologic role of the channel versus the kinase activity. This is particularly important, as the numbers of chronic inflammatory and autoimmune diseases resultant from unbalanced immune responses, such as multiple sclerosis or colitis, are continuously increasing.;100000;100000;FP7-PEOPLE-2012-CIG;/MC-CIG;LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN;DE;;;/LIF;1;0;0;1;0;0 104499;307986;STRONGINT;ONG;FP7-IDEAS-ERC;ERC-SG-PE2;FP7;The strong interaction at neutron-rich extremes;2012-09-01;2017-08-31;;'The strong interaction at neutron-rich extremes' (STRONGINT) will investigate the structure of matter at the neutron-rich frontier in the laboratory and in the cosmos based on chiral effective field theory (EFT) interactions. Chiral EFT opens up a systematic path to investigate many-body forces and provides unique constraints for three-neutron and four-neutron interactions. We will for the first time explore the predicted many-body forces in neutron matter and neutron-rich matter. One milestone will be set by the development of a systematic power counting for neutron-rich matter. This will enable us to carry out diagrammatic approaches, and to develop ground-breaking nonperturbative Monte-Carlo calculations. Our results will strongly constrain the nuclear equation of state at the extremes reached in core-collapse supernovae and neutron stars. Based on the developments for neutron-rich matter, we will investigate spin correlations and develop a systematic description of neutrino-matter interactions, which can set the new standard for supernova simulations. Our pioneering studies have revealed new facets of three-body forces in neutron-rich nuclei, such as their role in determining the location of the neutron dripline in oxygen and in elucidating the doubly-magic nature of calcium-48. We will investigate the impact of chiral three-nucleon forces on key regions in the r-process path and develop a chiral EFT for valence-shell interactions. This will open new horizons for understanding the shell structure of nuclei. Another milestone will be set by the first calculation of neutrino-less double-beta decay based on chiral EFT interactions and consistent electroweak currents. The proposed interdisciplinary problems are essential for a successful and quantitative understanding of these big science questions.';1495020;1495020;ERC-2012-StG_20111012;/ERC-SG;TECHNISCHE UNIVERSITAT DARMSTADT;DE;;;"/PSE;/SCI";1;0;0;1;0;0 102613;298238;COWAVE;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IOF;FP7;The interactions between turbulent penetrative convection and gravity waves: from laboratory experiments to geo- and astrophysical applications;2012-09-01;2014-08-31;;'In many geo and astrophysical situations, a turbulent convective fluid layer is separated from a stably stratified one by a relatively sharp interface. Examples include the oceanic upper mixed layer and underlying pycnocline zone, the atmospheric convective layer and overlying stratosphere, the convective and radiative zones in stars. In classical models, stratified zones are often postulated to be motionless. But it has been recognized that gravity waves generated at the convective interface by turbulent motions could be of fundamental importance regarding momentum and energy transport through the stratified layer, with global consequences on the system evolution. Despite several studies, the current treatment of convectively generated gravity waves still presents major weaknesses. Indeed, their generation mechanism, their typical amplitude, their time and space frequency spectra, and the amount of energy and momentum that they carry remain largely unknown. Besides, the action of global rotation (omnipresent in natural systems) has not been accounted for. The purpose of this project is to go beyond the state-of-the-art in investigating these questions experimentally, using the most recent technics of flow measurements. Simplified set-ups will be developed at the laboratory scale, keeping the main physical ingredients of natural configurations, and addressing all their interactions and non-linearities simultaneously, which is barely accessible to theory and numerics. Generic laws will be derived and validated, before being applied to stars, oceans and atmosphere. This project is by its essence interdisciplinary, lying at the frontier between fluid mechanics and geo/astrophysics. From our original approach, we envisage to find new horizons regarding the dynamics of mixed convective/stratified systems, of direct interest for practical and fundamental applications (e.g. parameterization in general circulation models for weather predictions, model of the Sun interior).';158469,65;158469,65;FP7-PEOPLE-2011-IOF;/MC-IOF;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FR;;;/SCI;1;0;0;1;0;0 103449;300614;GOV_SSI;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IEF;FP7;"""Urban Regeneration Governance for Smart, Sustainable and Inclusive Cities: An International Comparison of France and the UK""";2012-09-01;2014-08-31;;"'This proposal aims to support the career development of an experienced researcher, through an interdisciplinary research project that addresses a crucial policy issue of the 21st century, that of urban governance. The research will take an innovative approach to exploring governance of urban regeneration projects in two member states, France and the UK, being examples of countries with contrasting institutional, economic, social and cultural traditions in relation to government and governance. Using an innovative multidisciplinary theoretical framework, the scientific objectives of the research are: to critically analyse mechanisms for urban regeneration governance, including the interaction of private, public and civil society actors; to analyse the impact of these local governance mechanisms in contributing to a more sustainable city in the wider sense, in terms of economic competitiveness, environmental sustainability and social inclusion: that is, the city's objectives of being ‘smart, sustainable and inclusive’ (SSI); and to provide policy and research recommendations from the project for dissemination to a wide audience. The host institution for the researcher is the Triangle Laboratory, based at the Ecole Normale Superieure de Lyon. The Laboratory provides the ideal host for the project, offering a strong multidisciplinary environment, a network of international contacts, and an outstanding track record of training researchers. The research training objectives of the proposal are to train the fellow in a new methodology, discourse analysis, which she will then apply to the research; to complement the researcher’s knowledge of urban governance in the UK with in-depth understanding of the case in France, and thus to develop a cross-national comparative perspective; to participate in seminars and other events organised by the Laboratory; and to interact and collaborate with international scholars from different disciplines in areas of mutual interest.'";269096,4;269096,4;FP7-PEOPLE-2011-IEF;/MC-IEF;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FR;;;/SCI;1;0;0;1;0;0 87415;206994;REDIRECT;ONG;FP7-IDEAS-ERC;ERC-SG-SH1;FP7;Reconciling Biodiversity and Development through Direct Payments for Conservation;2008-07-01;2012-09-30;;"This project will help to meet the vital need for empirical research into the theory and practice of Payments for Environmental Services (PES). PES approaches to conservation have become rapidly more popular in the last few years, driven by compelling evidence of their effectiveness compared with indirect approaches to financing conservation. This research will exploit a current opportunity to build robust research protocols into the initial design of a PES scheme, thus allowing credible research into its outcomes. This will be undertaken through work with selected communities around the Nyungwe National Park in Rwanda. Communities will be offered cash transfers, contingent on their performance in relation to a set of conservation indicators. One of the great advantages of this project location is the availability of high quality ranger monitoring that, for example, provides regular geo-referenced data on the location of snares, tree-felling and other illicit activities. The outcomes of this experiment will be investigated through interdisciplinary research based on four main types of data. Firstly, data on forest user behaviour, based on the ranger data and additional transect studies; secondly, livelihood surveys that build an understanding of relationships between communities and park resources; thirdly, qualitative data, based on interviews and focus groups, to build an understanding of the social dynamics arising from introduction of the PES scheme; fourthly, public goods games to elicit data on attitudes towards the Park. The research findings will be of use to a wide range of African and international agencies with an interest in better understanding ways of reconciling biodiversity conservation and poverty alleviation. The results will provide a timely input to our understanding of the theory and practice of PES schemes.";1027633;1027633;ERC-2007-StG;/ERC-SG;UNIVERSITY OF EAST ANGLIA;UK;;;"/ECO;/SOC;/BUS";1;0;0;1;0;0 95753;255987;FOC-II;CLO;FP7-ICT;ICT-2009.8.0;FP7;Forecasting Financial Crises;2010-09-01;2014-02-28;;In this project we set up an interdisciplinary consortium of computer scientists, physicists, economists and policy makers to deal with the problem of understanding and forecasting systemic risk and global financial instabilities. By leveraging on expertise in the various disciplines, we want to provide a novel integrated and network-oriented approach to the issue. On one hand, we will offer a theoretical framework to measure systemic risk in global financial market and financial networks. On the other hand, we will deliver an ICT collaborative platform for monitoring systemic fragility and the propagation of financial distress across institutions and markets around the world. Experts will be able to evaluate algorithms and models to forecast financial crises as well as visualise interactively possible future scenarios.;3778077;2894484;FP7-ICT-2009-C;/CP;SCUOLA IMT (ISTITUZIONI, MERCATI, TECNOLOGIE) ALTI STUDI DI LUCCA;IT;"FUNDACIO BARCELONA MEDIA;THE TRUSTEES OF BOSTON UNIVERSITY;INSTITUT JOZEF STEFAN;National University Corporation, Kyoto University;CITY UNIVERSITY OF LONDON;CONSIGLIO NAZIONALE DELLE RICERCHE;EOTVOS LORAND TUDOMANYEGYETEM;EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;UNIVERSITA POLITECNICA DELLE MARCHE;EUROPEAN CENTRAL BANK;PARMENIDES STIFTUNG;RUDER BOSKOVIC INSTITUTE";"ES;US;SI;JP;UK;IT;HU;CH;DE;HR";"/SCI;/ITT";1;0;0;1;0;0 89564;202287;MEMBRANE DYNAMICS;ONG;FP7-PEOPLE;PEOPLE-2007-4-3.IRG;FP7;The role of membrane trafficking in immune cell function;2007-09-03;2011-09-02;;Recently, receptor signal transduction has been identified to occur not only at the plasma membrane, but also at various intracellular compartments. Hence, receptor trafficking and signal compartmentalization may contribute to a higher level of cellular organization. The proposal’s objective is to understand fundamental principals in the regulation and biology of membrane trafficking and signal compartmentalization, and to test them in a physiological context. The overall research concept is to study two immune specific regulators for small GTPases, RIN3 and ACAP1, which are involved in the regulation of membrane trafficking and the actin cytoskeleton. In a functional genomic approach, mice deficient for these genes will be generated and lymphocyte signaling and immune cell function/development will be used as a physiological read out to study the biological role of signal compartmentalization. The analysis of knock-out mice will be complemented by biochemical in vitro experiments to further dissect molecular mechanisms of RIN3/ACAP1 function. In addition the potential role of these molecules in the development of immune disorders, such as allergy/asthma will be analyzed. Thus, the study will provide novel insights into the complexity of functions regulated by signal compartmentalization, may have far reaching implications for our understanding of immune cell function in health and disease, and may offer an opportunity to develop novel therapeutical strategies in autoimmunity. The researcher is an internationally experienced and well recognized expert for membrane dynamics and trafficking. The proposed theme regarding the physiologic relevance of membrane dynamics demonstrates a high degree of originality and innovation in a very promising research field. The host, the Research Center Borstel, is characterized by an interdisciplinary approach combining basic sciences with clinical research providing an ideal scientific environment to conduct the proposed work.;100000;100000;FP7-PEOPLE-2007-4-3-IRG;/MC-IRG;FORSCHUNGSZENTRUM BORSTEL;DE;;;"/SCI;/COO";1;0;0;1;0;0 102410;280550;INSTANT;ONG;FP7-NMP;NMP.2011.1.3-1;FP7;Innovative Sensor for the fast Analysis of Nanoparticles in Selected Target Products;2012-03-01;2015-11-30;http://www.instant-project.eu;"INSTANT will face the challenge of the detection, identification and quantification of engineered nanoparticles (ENPs) in complex matrices such as cosmetic products and engineered food and drinks. Therefore, new detection methods and technologies are mandatory. This is completely in line with the Call FP7-NMP.2011.1.3-1 which deals especially with innovative, practically implementable and cost effective measurement approaches for ENPs in complex matrices. Recently emerging ENPs include Ag, SiO2, TiO2, ZnO, and organic NPs. The “Opinion of the Scientific Committee on the Potential Risks Arising from Nanoscience and Nanotechnologies on Food and Feed Safety” released by the European Food Safety Authority (EFSA) (2009) also highlights the urgent need for such a tool. Accordingly, the interdisciplinary project INSTANT will develop an innovative and integrated technology for monitoring the exposure of consumers to ENPs using a label free opto-electrochemical sensor array in combination with novel recognition elements. The SME driven INSTANT will develop an innovative, cost effective, and easy to use analytical tool to extract, detect and identify ENPs typically used in cosmetic products (e.g. sunscreen, toothpaste, deodorant, ...) and engineered food (e.g. instant soups, ketchup, ice cream, ...) and drinks (e.g. fruit juice, energy drinks, bottled water, ...). A crucial point of measuring in these complex matrices is the sample preparation and extraction. Therefore INSTANT will develop and integrate tailored extraction methods. Especially the size distribution of ENPs in the sample and the influence of the matrix on chemical and physical properties of the ENPs have to be taken into account. The INSTANT device will be designed to be used as a cost effective monitoring tool which is suitable for characterisation and classification of ENPs for the future implementation of quantitative structure-activity relationship studies.";4845125,74;3771946;FP7-NMP-2011-SME-5;/CP-TP;EBERHARD KARLS UNIVERSITAET TUEBINGEN;DE;"CORPUS DATA MINING HANDELSBOLAG;UNIVERSITAT WIEN;SOCIEDAD DE INVESTIGACION EN NANOESTRUCTURAS SL;UMEA UNIVERSITET;UNIVERSIDAD DE CORDOBA;BUNDESANSTALT FUER MATERIALFORSCHUNG UND -PRUEFUNG;NANORDIC OY;BIAMETRICS GMBH;SITEX 45 SRL;CORPUS DATA & IMAGE ANALYSIS AB";"SE;AT;ES;DE;FI;RO";/NNT;1;0;0;1;0;0 102964;298634;CAMLIT;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IIF;FP7;PERPETUATING CAMEROON ANGLOPHONE LITERATURE: A CRITICAL READING OF SELECTED WORKS;2012-09-01;2015-01-17;;"'The fundamental objective of this project is to critically assess some selected works of the immense corpus of Cameroon Anglophone Literature to ascertain its place not only in Cameroon and Africa, but in the European literary community. It seeks to examine critically the multivariate sociocultural, economic, political, ideological and linguistic issues of the different genres (drama, poetry and prose) that constitute Cameroon Anglophone Literature as distinctive from Cameroon Literature of English Expression. It also aims at showing that this literature has international standards and contributes to trans-cultural, social and political awareness. Based on interdisciplinary and multiple theoretical perspectives, it will use new historicist, postcolonial, psychoanalytical, feminist and philosophical discourse as interpretative paradigms. In this regard, it will wrestle with the Anglophoneness of the literature as linguistic or ideological, cultural perpetuity with regard to reasserting cultural identity and negotiating new spaces with Western encounters and globalization, gender deconstruction, national awareness and nation building and existentialist questions pertaining to the enigmas and complexities of human existence and experience. The objectives will be achieved through lectures and seminars with the participation of a research team at Munich University whose library has an updated corpus of the said literature. The outcome will be scholarly publications of essays, conference proceedings, and a monograph which can serve as a standard textbook Cameroon Anglophone Literature. Given that no systematic and standardised work has been carried out on this literature, this project will serve as a breakthrough and springboard to a mutually enriching academic exchange. It will provide an opening of new horizons not only to the researcher, but the host university and the international community with regard to academic and intellectual expansionism.'";231547,2;231547,2;FP7-PEOPLE-2011-IIF;/MC-IIF;LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN;DE;;;/SCI;1;0;0;1;0;0 185569;614964;CELLFITNESS;ONG;FP7-IDEAS-ERC;ERC-CG-2013-LS3;FP7;Active Mechanisms of Cell Selection: From Cell Competition to Cell Fitness;2014-06-01;2019-05-31;;The molecular mechanisms that mediate cell competition, cell fitness and cell selection is gaining interest. With innovative approaches, molecules and ground-breaking hypothesis, this field of research can help understand several biological processes such as development, cancer and tissue degeneration. The project has 3 clear and ambitious objectives: 1. We propose to identify all the key genes mediating cell competition and their molecular mechanisms. In order to reach this objective we will use data from two whole genome screens in Drosophila where we have identified 7 key genes. By the end of this CoG grant, we should have no big gaps in our knowledge of how slow dividing cells are recognised and eliminated in Drosophila. 2. In addition, we will explore how general the cell competition pathways are and how they can impact biomedical research, with a focus in cancer and tissue degeneration. The interest in cancer is based on experiments in Drosophila and mice where we and others have found that an active process of cell selection determines tumour growth. Preliminary results suggest that the pathways identified do not only play important roles in the elimination of slow dividing cells, but also during cancer initiation and progression. 3. We will further explore the role of cell competition in neuronal selection, specially during neurodegeneration, development of the retina and adult brain regeneration in Drosophila. This proposal is of an interdisciplinary nature because it takes a basic cellular mechanism (the genetic pathways that select cells within tissues) and crosses boundaries between different fields of research: development, cancer, regeneration and tissue degeneration. In this ERC CoG proposal, we are committed to continue our efforts from basic science to biomedical approaches. The phenomena of cell competition and its participating genes have the potential to discover novel biomarkers and therapeutic strategies against cancer and tissue degeneration.;1968062;1968062;ERC-2013-CoG;/ERC-CG;FUNDACAO D. ANNA SOMMER CHAMPALIMAUD E DR. CARLOS MONTEZ CHAMPALIMAUD;PT;UNIVERSITAET BERN;CH;"/BIO;/LIF;/SCI";1;0;0;1;0;0 99779;293572;INTEGRATION;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-CIG;FP7;Mechanistic studies of T-DNA integration into plant genome;2011-09-01;2016-12-23;;Plant genetic transformation is a fascinating process by which the Agrobacterium transforms its host by delivering a well-defined fraction of its own genome (designated transfer DNA or T-DNA) as a single-stranded (ss) DNA molecule (designated T-strand) into the host cell. The T-DNA integrates into the host genome and is expressed there. Many of the biological mechanisms that govern the transformation process remain poorly understood and our understanding of the mechanisms by which T-DNA molecules integrate into the host-cell genome is still sketchy. The T-DNA molecule does not code for the machinery needed for its transport and integration into the plant genome. Thus, the T-DNA sequence can potentially be replaced by any other sequence of interest without affecting the transformation and integration process, which is likely to be governed largely by plant proteins and machineries. T-DNA molecules were shown to be capturable by genomic double-strand breaks (DSBs), which led to the suggestion that DSBs may act as ‘hot spots’ for T-DNA integration. Data from my laboratory suggest that a double-stranded (ds) intermediate (dsT-DNA) may serve as a dominant substrate in the integration process. The mechanism by which T-strands are complemented to dsT-DNAs is still unknown and to the best of our knowledge, have never been studied and we have only recently begun to reveal the molecular mechanisms by which dsT-DNA molecules integrate into genomic DSBs. My hypothesis is that dsT-DNA intermediate molecules and genomic DSBs play a significant role in T-DNA integration and in my interdisciplinary proposal I plan to combine the use of functional assays, biochemical studies, genetic approaches and imaging methods to (i) unveil the molecular mechanism of T-strand complementation to dsT-DNA and (ii) study the role played by DSBs in capturing dsT-DNA molecules.;100000;100000;FP7-PEOPLE-2011-CIG;/MC-CIG;BEN-GURION UNIVERSITY OF THE NEGEV;IL;;;/SCI;1;0;0;1;0;0 105164;318117;NANOTHERM;ONG;FP7-ICT;ICT-2011.3.1;FP7;Innovative Nano and Micro Technologies for Advanced Thermo and Mechanical Interfaces;2012-09-01;2016-02-29;;Future electronic power devices and packages will need to demonstrate more performance and functionality at reduced cost, size, weight, energy consumption and thermal budget. Further, increasing reliability demands have also to be met by industry to be competitive in this growing multi-billion Euro market of heterogeneously integrated systems.To respond to these challenges, new innovative nano- and micro-technologies and materials, both of which are key enablers for advanced thermal and mechanical interfaces, have to be developed and compatibly integrated to obtain higher electrical, thermal and reliability performance under harsh environmental conditions.Nanotherm's objective is to take up these challenges in design, technology and test:Novel approaches to thermal technologies with superior electrical, thermal and thermo-mechanical properties will be developed in the project and demonstrated on automotive, avionics, solid-state lighting and industrial applications. Parallel routes will be followed addressing nano-sinter-adhesive bonding, phonon-coupled VACNT joining, nano-functionalised nano-filled adhesive die attach and graphene-enhanced surfaces. The main principle common to all technologies is the exploitation of nano-effects to obtain outstanding interconnect properties by especially developed processes.In parallel, a multi-scale and multi-domain modelling framework will furnish guidelines for materials design by various approaches from ab-inito up to continuum modelling and verified by corresponding experimental techniques.The consortium, composed of 18 partners from industry, SME and academia out of 8 European countries, embodies the necessary excellence and interdisciplinarity to address these tasks successfully. We are convinced that Nanotherm's results will enable the next generation of heterogeneously integrated power packages, cut down thermal interface resistance at least by 50% and impact also on other power system-in-package configurations.;9514464;6070000;FP7-ICT-2011-8;/CP;THALES SA;FR;"AMIC ANGEWANDTE MICRO-MESSTECHNIK GMBH;BME VIKING ELECTRICAL ENGINEERING INFORMATION TECHNOLOGY;ROBERT BOSCH GMBH;ATEP - AMKOR TECHNOLOGY PORTUGAL SA;HERAEUS DEUTSCHLAND GMBH & CO KG;Amepox;FUNDACIO INSTITUT CATALA DE NANOCIENCIA I NANOTECNOLOGIA;INFINEON TECHNOLOGIES AG;BUDAPESTI MUSZAKI ES GAZDASAGTUDOMANYI EGYETEM;SHT SMART HIGH-TECH AB;TECHNISCHE UNIVERSITAET CHEMNITZ;PHILIPS ELECTRONICS NEDERLAND B.V.;TECHNISCHE UNIVERSITEIT EINDHOVEN;BERLINER NANOTEST UND DESIGN GMBH;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;POLITECHNIKA WROCLAWSKA;CHALMERS TEKNISKA HOEGSKOLA AB";"DE;HU;PT;PL;ES;SE;NL;FR";/NNT;1;0;0;1;0;0 94344;249930;CORALWARM;ONG;FP7-IDEAS-ERC;ERC-AG-ID1;FP7;Corals and global warming: The Mediterranean versus the Red Sea;2010-06-01;2016-05-31;;CoralWarm will generate for the first time projections of temperate and subtropical coral survival by integrating sublethal temperature increase effects on metabolic and skeletal processes in Mediterranean and Red Sea key species. CoralWarm unique approach is from the nano- to the macro-scale, correlating molecular events to environmental processes. This will show new pathways to future investigations on cellular mechanisms linking environmental factors to final phenotype, potentially improving prediction powers and paleoclimatological interpretation. Biological and chemical expertise will merge, producing new interdisciplinary approaches for ecophysiology and biomineralization. Field transplantations will be combined with controlled experiments under IPCC scenarios. Corals will be grown in aquaria, exposing the Mediterranean species native to cooler waters to higher temperatures, and the Red Sea ones to gradually increasing above ambient warming seawater. Virtually all state-of-the-art methods will be used, by uniquely combining the investigators expertise. Expected results include responses of algal symbionts photosynthesis, host, symbiont and holobiont respiration, biomineralization rates and patterns, including colony architecture, and reproduction to temperature and pH gradients and combinations. Integration of molecular aspects of potential replacement of symbiont clades, changes in skeletal crystallography, with biochemical and physiological aspects of temperature response, will lead to a novel mechanistic model predicting changes in coral ecology and survival prospect. High-temperature tolerant clades and species will be revealed, allowing future bioremediation actions and establishment of coral refuges, saving corals and coral reefs for future generations.;3332032;3332032;ERC-2009-AdG;/ERC-AG;BAR ILAN UNIVERSITY;IL;ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA;IT;/SCI;1;0;0;1;0;0 103832;302896;SYNEURGY;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IOF;FP7;Synergistic modeling of gene-brain couplings with applications in affective neuroscience;2012-07-01;2015-06-30;;"Exploiting cross-modal integration for enhanced power and sensitivity, the recently emerged field of imaging genomics is at the frontline of available tools for identifying genes which influence the neurobiology of human behavior and psychiatric illness. Computational approaches are not, however, up to par with the complexity of the disparate data: there is an urgent need for integrative predictive modeling to overcome the interdisciplinary fragmentation between genomics and neuroimaging to harvest the full potential of the data. The methodological objective of this project is therefore to develop and implement integrative cross-modal algorithms for synergistic modeling of human genetic effects on brain responses patterns. To this end, the project will use tools from machine learning which allow powerful, multivariate, generic, data-driven, general purpose predictive modeling. Application side, the project will target the neurobiology of affective behavior and disorders through modeling gene-brain correlates in a population of individuals carrying a mutation resulting in atypical sense of affective touch and insensitivity to pain. Employing a cross-modal, multi-disciplinary approach, integrating genomics, neuroimaging and engineering at the frontier of neuroscience research, the project enables holistic modeling of genetic correlates of human behavior and psychiatric conditions revealing new therapeutic avenues. The project embodies the work program by providing excellent international, multi-disciplinary, cross-modal academic training, establishing a solid yet dynamic basis for a prolific long-term scientific career for the Fellow. The project will increase the attractiveness of the ERA through promoting the world-leading Swedish neurobiology research and facilitate mutually beneficial relations with Singapore; moreover, the project will aid the ERA in benefiting from rather than competing with the growing science and technology investments in Asia.";250483,2;250483,2;FP7-PEOPLE-2011-IOF;/MC-IOF;LINKOPINGS UNIVERSITET;SE;GOETEBORGS UNIVERSITET;SE;/SCI;1;0;0;1;0;0 101676;290246;RAPID;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-ITN;FP7;Rheumatoid Arthritis and Periodontal Inflammatory Disease (RAPID);2012-04-01;2016-03-31;http://rapid-itn-project.eu/;"The most prevalent chronic inflammatory diseases of humans are complex disorders of multifactorial aetiology influenced by genes, the environment and their interactions. Periodontitis (PD) and rheumatoid arthritis (RA) are two such chronic inflammatory diseases associated with significant morbidity and mortality, and have recently shown to have a bi-directional association. Moreover, the prevalence of both increases substantially with age, and given both the Europe-wide ageing population and the impact of both diseases upon the economy, health and quality of life, it is clear that novel and more cost effective approaches to management are urgently required. A key research goal of this project is to improve understanding of the pathogenesis of RA and PD and their inter-relationships, through the study of common risk factors linked to the activation of host and bacterial derived protein citrullination, which subsequently generates pro-inflammatory auto-antigens in the joints and periodontal tissues. Our vision is that enhanced biological understanding in this area will inform the future development of new approaches to disease prevention, early diagnosis and novel therapies. RAPID aims to provide a significant contribution to this by establishing a first class, dynamic training network of 12 partners and 5 associated partners for early career researchers who will be able to advance chronic inflammatory disease research by working across sectors and disciplines. The network is an interdisciplinary cooperative of medical and dental clinicians, epidemiologists, bio-scientists, industrial scientists, media and commercialization specialists. The aim of the Training Programme is to increase the knowledge base and experience of trainees in the different research areas and to develop their transferable skills for future careers in industry or academia, whilst advancing the field through new discovery.";4312151,08;4312151,08;FP7-PEOPLE-2011-ITN;/MC-ITN;THE UNIVERSITY OF BIRMINGHAM;UK;"ANAXOMICS BIOTECH, S.L.;Unilever research and development Vlaardingen BV;AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS;UNIWERSYTET JAGIELLONSKI;CHARITE - UNIVERSITAETSMEDIZIN BERLIN;IMAGEN BIOTECH LIMITED;KAROLINSKA INSTITUTET;DEUTSCHES INSTITUT FUER ERNAEHRUNGSFORSCHUNG POTSDAM REHBRUECKE;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;UNIVERSITY OF GLASGOW;ERNST-MORITZ-ARNDT-UNIVERSITÄT GREIFSWALD;UNIVERSITETET I BERGEN;ASTON UNIVERSITY";"ES;NL;PL;DE;UK;SE;NO";"/LIF;/SCI";1;0;0;1;0;0 103670;301155;TURNTAKE;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IIF;FP7;Turn-Taking in Human-Robot Interactions: a Developmental Robotics Approach;2012-10-01;2014-09-30;;"This project’s main goal is to advance the field of human-robot interaction, specifically with robots that can adjust to natural interaction rhythms, while engaged on a joint task. Robots capable of open-ended and engaging interactions are useful: as learners, with humans as instructors (e.g. by demonstration, by imitation), as teachers, and as assistants of the elderly, or disabled. Mounting evidence shows that seamless timing of turn-taking–and the capability for dynamic control of a turn-taking rhythm–is associated with perceived quality and learning outcomes, in adult-adult, and in human-robot social exchanges. Moreover, in infancy, turn-taking dynamics predict emotional, social, and cognitive developmental outcomes. The workplan proposes a novel 2-step developmental approach: (1) study developmental changes in turn-taking dynamics when children are engaged in open-ended joint play with a parent–measured with motion-capture of participants’ body movements; and (2) and apply these results to extend and test a robotic platform (ARoS) developed at the host institution. In addition, the proposed empirical studies will have far-reaching consequences, beyond human-robot interaction design, in the social, emotional, and cognitive development fields, including clinical applications. The workplan will be supported by a novel interdisciplinary collaboration of a robotics and an experimental psychology laboratory at the host.";208672,4;208672,4;FP7-PEOPLE-2011-IIF;/MC-IIF;UNIVERSIDADE DO MINHO;PT;;;/SCI;1;0;0;1;0;0 105312;305532;HEALTH-2-MARKET;ONG;FP7-HEALTH;HEALTH.2012.4.1-2;FP7;From Health Research to Market – Advanced Services and Training Actions for the IPR Management and Business Exploitation of the EU-funded Research Results in Health/life sciences;2012-09-01;2015-08-31;http://www.health2market.eu/;Health-2-Market is an ambitious project aiming to boost the economic exploitation of EU-funded research results in the area of Health/life science. The project focuses on the actual Health/life science knowledge generators, namely the researchers, involved in EU-funded research in Health with a view to cultivate to them an enhanced innovation and entrepreneurial culture. More specifically, Health-2-Market will aim at providing Health researchers with the necessary knowledge and skills for more viable IPR management as well as market exploitation of their results through the setting up of new business ventures in health/life science sectors or in a more broad sense through their more active involvement in interdisciplinary cooperation actions. More specifically, Health-2-Market is expected to offer a set of high-level services including advanced training courses,ad-hoc and on demand counselling as well as specific coaching (both through web as well as face-2-face) addressing innovation issues such as: IPR and asset management, formulation of business and exploitation plans, preparation for the launch of start-ups in health/life science as well as on demand knowledge transfers. Health-2-Market services will be offered by a pool of experienced internal specialists as well as external ones coming from leading academic and industrial organisations. The provided services will be escalating to address the needs of the potential target groups: Web (e-learning) courses for broader audience, two-day seminars on specific topics, advanced training courses (intensive training academies), hands-on support and ad-hoc counselling services either through face-to-face meetings, or distance ones, etc. The project will cover all EU MS and AC through its broad partnership as well as through a network of regional experts that will be set up. The project with take into account existing networks and services already deployed as the EEN, the Fit for Health Network as well as the NCP network.;2394509,5;1999785;FP7-HEALTH-2012-INNOVATION-1;/CSA-CA;INNO AG;DE;"Q-PLAN INTERNATIONAL ADVISORS PC;AGENZIA PER LA PROMOZIONE DELLA RICERCA EUROPEA;IE UNIVERSIDAD;INNO TSD;ENGAGE - KEY TECHNOLOGY VENTURES AG;SKEMA BUSINESS SCHOOL;WHITE RESEARCH SPRL;EUROPA MEDIA SZOLGALTATO NON PROFITKOZHASZNU KFT;GOETEBORGS UNIVERSITET";"EL;IT;ES;FR;DE;BE;HU;SE";/SCI;1;0;0;1;0;0 100632;294192;CHROMATRANSCRIPT;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-CIG;FP7;Role of the chromatin architecture in the regulation of gene transcription;2012-01-01;2015-12-31;;"The complex architecture displayed by the chromatin inside the nucleus of eukaryotic cells plays an important role in several key cellular processes such as the regulation of gene expression, DNA replication and DNA repair. The dynamics of this chromatin architecture remains however poorly characterized. While at “steady state” the chromatin organization is thought to be relatively stable along the entire interphase, dramatic modifications of this architecture has been observed in response to external stimuli. In particular, the activation or repression of gene transcription is often associated with local changes in the level of chromatin compaction and with gene repositioning inside the nucleus. A precise understanding of the mechanism underlying this chromatin reorganization is impeded by the lack of a complete description of the dynamics of the restructuring process. With the “ChromaTranscript” project, the researcher proposes to investigate the process of nuclear restructuring in association to transcriptional activation or repression of estrogen-regulated genes using an original approach at the interface between biology, physics and advanced microscopy. The three following questions will be investigated: 1) What is the dynamic of the nuclear reorganization process at the scale of a single chromosome ? 2) What are the changes in the fine chromatin structure underlying the micron-scale nuclear reorganizations studied in 1) ? 3) Is nuclear reorganization the cause or the consequence of the change in transcription activity ? The interdisciplinary approach which is proposed in the project combines tagging methods, used to label in fluorescence single chromosome or specific gene loci in living cells, and advanced light microscopy methods allowing the monitoring, at different scales in space and time, of the process of nuclear restructuring in association to transcription modulation.";100000;100000;FP7-PEOPLE-2011-CIG;/MC-CIG;UNIVERSITE DE RENNES I;FR;;;/SCI;1;0;0;1;0;0 104833;314836;REFERENCE;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IRSES;FP7;Research Network on Flexible Risk Assessment and Decision Science;2012-09-03;2016-09-02;;The overall aim of this proposed exchange programme is to bring together an international team of researchers, with a wide variety of skills in order to develop a formal safety assessment framework with appropriate support models for application to marine, oil and gas, supply chain management nuclear and transport areas. Life cycle safety of large complex engineering systems will be investigated in terms of the design, manufacture, installation, commissioning, operations and maintenance phases. A variety of appropriate subject topics such as uncertainty modelling, expert knowledge elicitation, human and organizational factor study, risk prediction, software tools, probabilistic risk estimation, cost benefit modelling and multiple criteria decision making will be investigated in the selected industrial sectors using the expertise the partners of the consortium possess. The proposal is for a project of five partners (3 EU members, 1 AS member and 1 ICPC member) with extensive exchange of both experienced researchers (ERs) and early stage researchers (ESRs) during four years to fully explore the complementary strengths and synergies within the consortium. This project will support and reinforce the collaborations amongst the participants and help establish a long-term research co-operation. The research will increase the European research capacity in this vital and rapidly developing field, and also maintain and enhance the EU’s leading position in the area. Moreover, the interdisciplinary nature of the proposed exchange programme offers a link for research and training of the involved ERs and ESRs in a collaborative academic environment. It also bridges both the gaps between fundamental and applied research and research in risk assessment and decision science.;384300;384300;FP7-PEOPLE-2012-IRSES;/MC-IRSES;LIVERPOOL JOHN MOORES UNIVERSITY;UK;"ECOLE CENTRALE DES ARTS ET MANUFACTURES;THE UNIVERSITY OF MANCHESTER;NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU";"FR;UK;NO";/SCI;1;0;0;1;0;0 98813;267877;SHRINE;ONG;FP7-IDEAS-ERC;ERC-AG-ID1;FP7;Seamless Human Robot Interaction in Dynamic Environments;2011-05-01;2016-04-30;;"A major barrier exists preventing today's and future interactive robots from smoothly acting in joint workspaces in real-world and in an efficient and socially compatible manner on human terms. Robots lack the ability to plan actions in a timely manner in order to match dynamics of environment and humans. Environment and human motion dynamics have to be known and represented in a way that sufficient prediction and planning quality is provided even in complex dynamic scenarios with many interaction partners accounting for social aspects. Robots need to be aware of human communication principles in order to estimate intentions and to predict future behavior. SHRINE aims at breaking this barrier in order to provide future robots with interactive capabilities similar to those of humans and to facilitate joint action of humans and robots sharing one world. SHRINE targets an integrated approach towards interaction in complex dynamically changing human-centered environments in terms of a hierarchical framework. SHRINE will investigate dynamic systems approaches to haptic and affective communication in human-robot interaction to consider intention and affect within an integrated robotic control and action planning framework. SHRINE seeks to extend the conventional, purely physics-driven motion prediction approach by estimating intentions of humans and merging these estimates with the dynamic physical environment model. SHRINE will integrate findings from psychology and sociology into the latest path planning and navigation methods. The approach of SHRINE is highly innovative with pioneering character in the integrated approach as well as in the various sub-fields, strongly interdisciplinary bridging engineering approaches and human sciences, and constitutes visionary high-risk research with high-impact on future technologies in the fields of personal assistant and care robots, human-robot collaboration in manufacturing, and autonomous robots in hum-centered environments.";2490000;2490000;ERC-2010-AdG_20100224;/ERC-AG;TECHNISCHE UNIVERSITAET MUENCHEN;DE;;;/SCI;1;0;0;1;0;0 100402;281331;COMPLEXNMD;ONG;FP7-IDEAS-ERC;ERC-SG-LS1;FP7;NMD Complexes: Eukaryotic mRNA Quality Control;2012-02-01;2016-11-30;;"Nonsense-mediated mRNA decay (NMD) is an essential mechanism controlling translation in the eukaryotic cell. NMD ascertains accurate expression of the genetic information by quality controlling messenger RNA (mRNA). During translation, NMD factors recognize and target to degradation aberrant mRNAs that have a premature stop codon (PTC) and that would otherwise lead to the production of truncated proteins which could be harmful for the cell. A wide range of genetic diseases have their origin in the mechanisms of NMD. Discrimination of a PTC from a correct termination codon depends on splicing and translation, and it is the first and foremost step in human NMD. The molecular mechanism of this process remains elusive to date. In the research proposed, I will undertake to elucidate the molecular basis of translation termination and induction of NMD. I will study complexes involved in human translation termination at a normal stop codon and involved in NMD. I will employ an array of innovative techniques including recombinant production of human protein complexes by the MultiBac system, mammalian in vitro translation, mass spectrometry for detecting relevant protein modifications, biophysical techniques, mutational analyses and RNA-interference experiments. Stable ribosomal complexes with termination factors and complexes of NMD factors will be used for structure determination by cryo-electron microscopy. State-of-the-art image processing will be applied to address the inherent heterogeneity of the complexes. Hybrid approaches will allow the combination of cryo-EM structures with existing high-resolution structures of factors involved for generation of quasi-atomic models thereby visualizing molecular mechanisms of NMD action. This interdisciplinary work will foster our understanding at a molecular level of a paramount step in mRNA quality control, which is a vital prerequisite for the development of new treatment strategies in NMD-related diseases.";1176825;1176825;ERC-2011-StG_20101109;/ERC-SG;EUROPEAN MOLECULAR BIOLOGY LABORATORY;DE;;;"/BIO;/LIF";1;0;0;1;0;0 95782;251992;SOCIALMAPONPARIS;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IEF;FP7;THE SOCIAL MEANING OF IMAGES: ADVERTISING POSTERS IN THE FIRST HALF OF THE 20TH CENTURY IN PARIS;2010-09-01;2012-04-30;;With this fellowship proposal I intend to explore the cultural context of the city of Paris in the first half of the 20th century, through the analysis of a specific cultural object: the advertising poster. My research will look at these posters as “social events” that create new historical identities through a communicative and symbolic efficacy. In this way I analyze these images as a real source of documentation of social practices, and as main social actors in the communicative interactions. My work will necessarily be interdisciplinary, merging together the textual meaning sciences and a narrative approach with the history of graphic arts and social-interaction-oriented methodologies. My research will also concern the relation between art and advertising during the birth of a modern city. In general I can state that, from their beginnings in the 19th century with Manet’s posters, the relation between the poster and Paris is a primal binomial that engendered the future evolution of advertisting arts, with influences still visible today. This is true not only in Paris but also in many other European cities. This is the reason why, by studying the cultural identity of Paris, we will also be studying an important aspect of a more general European identity.;132538;132538;FP7-PEOPLE-2009-IEF;/MC-IEF;ECOLE DES HAUTES ETUDES EN SCIENCES SOCIALES;FR;;;"/SCI;/EDU;/ITT";1;0;0;1;0;0 99107;274184;GASTRONEUROPEP;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-RG;FP7;Gastrointestinal and neuropeptides regulating food intake in fish in response to dietary lipid composition;2011-10-01;2014-09-30;;'There is an urgent need to replace fish oil (FO) and meal (FM) from wild stocks in aquaculture diets with more sustainable alternatives, being vegetable oils (VO) the primary candidates. However, these oils are devoid of essential n-3 long-chain PUFA (LC-PUFA) and can be particularly rich in n-6 PUFA, leading to imbalances in the n-6/n-3 ratio. This situation is similar to what is presently observed in other animal production sectors as well as in human nutrition. It is relatively well established how these changes in dietary lipid composition might affect lipid metabolism but potential effects on the regulation of appetite and food intake mediated by gastrointestinal and neuropeptides are possible and have been hardly investigated. This will be the objective of the present project, which will employ an interdisciplinary approach combining traditional nutritional and physiological studies with molecular analyses to evaluate potential impacts of more sustainable feed formulations on the regulation of food intake, while also uncovering the mechanisms behind it. The knowledge gained from this project is of high scientific and socio-economical importance to the future development and expansion of the European aquaculture industry. In addition, if physiological mechanisms of regulation of appetite and satiety in fish are similar to those in mammals, as has been suggested, knowledge gained might be applicable to other animal production sectors and even human nutrition, including studies of nutritional disorders (e.g. obesity). Finally, the effects of FO replacement by VO in aquaculture diets on lipid metabolism have been the research focus of the candidate in the past 3 years. The present project would thus enable the transfer of knowledge and competence from a northern European to a Mediterranean aquaculture context, while allowing the reintegration within an Institution with high opportunities for professional development and stabilization.';45000;45000;FP7-PEOPLE-2010-RG;/MC-ERG;INSTITUT DE RECERCA I TECNOLOGIA AGROALIMENTARIES;ES;;;/SCI;1;0;0;1;0;0 99862;293416;AUTOPHAGTUBERCULOSIS;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-CIG;FP7;MOLECULAR MECHANISMS OF AUTOPHAGY REGULATION IN TUBERCULOSIS;2011-08-01;2015-07-31;;"Mycobacterium tuberculosis (M.tb), etiologic agent of tuberculosis (TB), is still the leading cause of mortality by single bacterial infection worldwide. Annually, these air-borne bacilli kill almost 2 million people around the globe. M.tb is an extremely successful pathogen that have developed several strategies to neutralize the host immune defenses. One of significance is the block of phagosome maturation which results in survival and replication of M.tb inside macrophages. Autophagy is a cellular lysosomal degradative process which plays a fundamental role in immune responses to M.tb infection. Indeed, multiple reports show that extracellular inducers of autophagy promote phagosome maturation and killing of M.tb by macrophages. Furthermore, autophagy enhances BCG vaccine efficiency and antigen presentation. Although, M.tb succumbs to induced-autophagy, a recent study indicates that virulent M.tb can also modulate basal autophagy to survive intracellularly. Despite important progresses made in the research field of autophagy and mycobacterial infection, how M.tb regulates autophagy and its role in virulence remains largely unknown. To gain further insights into M.tb-autophagy interplay, we propose to decipherer the molecular mechanisms involved in autophagy regulation by M.tb using original, interdisciplinary and complementary approaches. We will (1) examine the correlation between virulence, pathogenicity of mycobacteria and autophagy modulation in human macrophages; (2) determine autophagy signaling pathways regulated by M.tb; (3) identify new M.tb factors that modulate autophagy. This project proposal will expand our understanding of the intricate relationship between M.tb and autophagy and its role in virulence which should help in the future design of innovative therapeutics for the fight against TB. Moreover, manipulating host autophagy might be one significant alternative for elimination of multi- and extensively-drug-resistant M.tb strains (M/XDR-TB).";100000;100000;FP7-PEOPLE-2011-CIG;/MC-CIG;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FR;;;/SCI;1;0;0;1;0;0 103048;296700;BESTT;ONG;FP7-JTI;JTI-CS-2011-1-ECO-02-010;FP7;Development, Construction and Integration of Bench Systems for Ground Thermal Tests;2011-11-01;2014-12-31;http://bestt.eu/;'The work within BESTT is allocated within seven work packages which lift the current know-how and demands for technological solutions step-by-step to a new innovative level. The consortium, consisting of three experienced companies covers the capabilities of developing and implementing a complex test bench by their experience in the field of manufacturing and standardisation (TEMES), modelling and engineering of complex plants (Modelon) and development and implementation of complex test benches (Streit). The development process will be created by this interdisciplinary experts consortium in an innovative iterative way which means, that short development cycles will go through the evaluation of an industrial manufacturer, a specialist company for test bench construction and a modelling experts company that will be the mathematic backbone on the way to the best solutions. Based on the results of the first work package a detailed planning process will be executed in WP2 “Design”. After the construction of the different custom parts in WP3, the integration of these components into the test facility will be carried out. To guarantee the operational functionality of the test bench, extensive operational tests will be executed by the consortium partners in WP5 “Operational testing'. With this consortium three strong expert companies will work together on the development of a step-change test environment for future technologies especially the more-electrical aircraft. The consortium will be managed by STREIT, which is an experienced engineering and plant construction company that already participated successfully in two FP projects.';1994470;1495852,5;SP1-JTI-CS-2011-01;/JTI-CS;STREIT-TGA-GMBH&CO.KG;DE;"MODELON GMBH;TEMES ENGINEERING GMBH";DE;/SCI;1;0;0;1;0;0 103266;299240;LIFENET;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IOF;FP7;New Algorithmic and Mathematical Tools to Construct a Net of Life;2012-05-01;2015-04-30;;"Phylogenetics, the study of evolutionary relationships among groups of species, is a well-established interdisciplinary scientific field. Until today, phylogeneticists put a lot of effort into the precise reconstruction of evolutionary trees. However, in recent years, the research focus on reconstructing phylogenetic trees is turning towards the reconstruction of phylogenetic networks because evolution cannot be properly represented as a tree. For example, a comparison of several trees that all represent a given set of present-day species and have been reconstructed for different genetic loci often reveals conflicting tree topologies. These discrepancies are not always due to missampling or uncertainty in the tree reconstruction method, but rather due to reticulation (e.g. horizontal gene transfer, hybridization, or recombination). Since phylogenetic networks are far more complex than phylogenetic trees, new mathematical and computational tools are needed. This proposal suggests new directions of research within the broad area of phylogenetic networks. First, we will develop new (fixed-parameter) algorithms to analyze intrahost recombination in viruses and apply them to biological data sets. This will provide new insight into the evolution of RNA viruses (e.g. HIV), which is essential in the development of any medication. Second, noting that many questions that are polynomial-time solvable for phylogenetic trees are NP-hard for when stated in terms of networks, we will tackle these harder questions by using novel methodology. Instead of directly solving a problem for a network, we will transform a given network into a tree by using the concept of tree-decompositions, and then solve an `easier' problem for the obtained tree. In particular, we will investigate problems related to the parsimony score of a phylogenetic network and supernetworks.";192461,62;192461,62;FP7-PEOPLE-2011-IOF;/MC-IOF;EBERHARD KARLS UNIVERSITAET TUEBINGEN;DE;;;/SCI;1;0;0;1;0;0 96256;268266;THYROIDANTIOXIDANT;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-RG;FP7;Role of the Keap1/Nrf2 antioxidant response system in thyroid gland homeostasis and thyroid cancer;2010-11-01;2014-10-31;;"Recently, it has been discovered that the thyroid gland has increased ability to withstand oxidative stress compared to other organs. This important feature allows the gland to maintain its homeostasis in the face of increased burden of free radicals produced during iodine metabolism for thyroid hormone synthesis. Iodine deficiency and goiter are associated with increased oxidative stress in the thyroid. While some antioxidant enzymes are known to be upregulated in the thyroid under such conditions, the broader regulatory mechanisms of oxidative stress resistance remain unknown. The proposed research aims to investigate the role of the major antioxidant response system orchestrated by the transcription factor Nrf2 in thyroid gland homeostasis and thyroid cancer. Specifically, it will examine whether Nrf2 regulates the thyroid’s antioxidant defenses; whether Nrf2 activity in the thyroid is altered during iodine deficiency and goitrogenesis; and whether constitutive Nrf2 activation by somatic mutations is associated with thyroid cancer. These investigations will utilize mouse knockouts of Nrf2 and wild-type animals, primary thyroid cell cultures derived from these mice, and archived thyroid cancer samples from human subjects. This work has implications for the management of iodine deficiency and the prevention of thyroid carcinogenesis. This interdisciplinary research project will be executed by Dr. Gerasimos Sykiotis, a translational investigator who has prior research experience in thyroid gland pathophysiology and has acquired state-of-the-art expertise with the Nrf2 antioxidant response system in the country of origin (USA). The University of Patras Medical Center is a highly qualified host organization as it has in place both the nrf2-/- animals and the human thyroid cancer samples. Lasting professional integration, international collaborations with the USA and European countries, and advanced European competitiveness are features of this proposal.";100000;100000;FP7-PEOPLE-2010-RG;/MC-IRG;PANEPISTIMIO PATRON;EL;;;/SCI;1;0;0;1;0;0 96021;253773;MAN-U;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IEF;FP7;Managing uncertainties in flood risk and climate change assessment: An exploratory study;2011-03-01;2012-02-29;;The overall aim of Man-U is to improve our understanding and management of uncertainties arising from the intersection of flood risk assessment and climate change projection with policy making. While the technical and scientific challenges involved in assessing the impacts of climate change on flood risks are enormous, if anything, the institutional challenges involved in using that science for policy making and the development of adaptation options are even greater. Man-U concentrates on this interplay of science and policy. It explores how first order scientific uncertainties about future flood risk are amplified by various institutional risks arising from the uncertainties of the policymaking process itself. In addressing the relationship between these dual challenges, Man-U is both scientifically innovative and policy relevant. Man-U takes a interdisciplinary perspective and explores (i) how flooding, the risks from climate change, and the uncertainties attributed to knowledge of them are framed, (ii) whether and how those framings are contested by different science and policy actors involved in flood risk assessment and (iii) with what implications for the development of adaptation actions and strategies. To explore these frames and conflicts, Man-U focuses on the particular case of England and conducts qualitative interviews with science and policy makers (n=60). Man-U will advance the state-of-the-art of understanding the institutional challenges of translating the scientific assessments of the impacts of climate change on flood risks into adaptation actions and strategies.;87451,6;87451,6;FP7-PEOPLE-2009-IEF;/MC-IEF;KING'S COLLEGE LONDON;UK;;;"/SCI;/EDU;/ITT";1;0;0;1;0;0 102747;268379;INTOTOMORPHOGENESIS;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-RG;FP7;in toto imaging of embryonic morphogenesis: collective cell movements and symmetry breaking;2011-09-22;2015-09-21;;Successive processes of symmetry breaking are occurring during the sequence of early embryonic morphogenesis. These fascinating events raise fundamental questions that are still under debate and are challenging to investigate. In parallel, recent advances in fluorescent reporters, microscopy and image processing, make possible investigating the dynamics of large cell populations in a developing embryo. It led to the emergence of the in toto imaging concept and provides a unique opportunity to study embryonic development from the scale of the cellular mechanisms to the entire organism. In this context, the purpose of this proposal is to bring novel approaches and techniques of in toto imaging to dissect fundamental processes involved in anterior-posterior symmetry breaking and axis specification in early mammalian embryos. The combination, characterization and development of cutting-edge microscopy, optical manipulation and image processing techniques will enable us to investigate the collective movement of the visceral endoderm in early mouse embryo. This process is the first morphological event that breaks the anterior-posterior symmetry. This study should provide a detailed understanding of the mechanisms involved in the anterior-posterior polarity in mouse embryo. It should also illustrate the crucial role of individual cell behaviors in the emergence of large scale morphogenetic events. This interdisciplinary project will be conducted at Institut Jacques Monod (IJM, Paris). Willy Supatto, the principal investigator, will use his training and experience in optics, biophysics and developmental biology to start a new research activity within Jérôme Collignon’s team at IJM.;100000;100000;FP7-PEOPLE-2010-RG;/MC-IRG;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FR;;;/SCI;1;0;0;1;0;0 101718;293638;DIASIN;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-CIG;FP7;Integrative Eco-mechanics of Diatom Sinking: Cellular Physiology, Complex Advection and the Biological Carbon Pump;2012-01-01;2015-12-31;;"'Perhaps the most striking example of the influence of aquatic microorganisms in global cycles is their role in the oxygenation of the Earth's atmosphere and the transfer of photosynthetically fixed carbon from the ocean's surface to the deep ocean through sinking, a mechanism referred to as the Biological Carbon Pump, the process responsible for most of the oceanic uptake of anthropogenic CO2. Mainly driven by phytoplankton sinking, the Biological Carbon Pump is, at its core, a fluid dynamical problem coupling physiological processes with biogeochemical cycles. As such, it spans multiple levels of biological organization and its study requires an integrative and interdisciplinary approach. This proposal aims at critically advancing our knowledge of the biological pump and its response to global changes in the environment by breaking through the current physiological bottleneck and examining the range of scales necessary to predict what the future is likely to hold. Specifically, I will focus on understanding the organism's role in organism-environment linkages, promoting phytoplankton to an active - physiologically controlled - performer in the carbon cycle. The interplay between active physiological responses and fluid transport, in what I like to call Complex (or Intelligent) Advection, remains largely unexplored whereas its consequences for biogeochemical cycles in the ocean are of paramount significance. The role of organisms in organism-environment interactions, its study through the integration of living and physical systems analysis, and its repercussions for the time course of adaptation and acclimation are three of the 'Grand Challenges' in organismal biology, identified by the Executive Committee of the Society for Integrative and Comparative Biology (SICB). All three challenges will be tackled within the proposed research program for the case of one of the most successful groups of eukaryotic micro-organisms in aquatic environments: the diatoms.'";100000;100000;FP7-PEOPLE-2011-CIG;/MC-CIG;UNIVERSITAT DE LES ILLES BALEARS;ES;;;/SCI;1;0;0;1;0;0 102835;300901;VISTO;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IIF;FP7;Visualizing tolerance induction: behavior and function of regulatory T cells during the establishment of materno/fetal tolerance;2012-03-01;2014-02-28;;"The presence of foreign (allogenic) tissue in a host yields an immune response with the goal to destroy the tissue. During pregnancy, however, the semiallogenic fetus is allowed to grow within the maternal uterus. This ‘immunological paradox of pregnancy’ has received much attention because of its therapeutic implications in organ transplantation and autoimmune diseases.While it has recently been established that regulatory T cells are essential in establishing tolerogenic conditions during pregnancy, little is known about where and when T regulatory act. I will characterize, using transgenic mouse lines and intra-vital two photon microscopy, the spatio-temporal characteristics of T regulatory cell recruitment at the materno/fetal interface. I will analyze the dynamics of cellular interactions between T regulatory cells with other immune system cells under physiological conditions and in a mouse model of spontaneous abortion. Finally, I will use a candidate gene approach to reveal similarities between molecular mechanisms of materno/fetal tolerance and tumor immune escape. A better understanding of the mechanisms leading to materno/fetal tolerance will have therapeutic implications for the treatment of patients with recurrent spontaneous abortion and pre-eclampsia, for organ transplantation and for autoimmune diseases. Moreover, the interdisciplinary comparison of similarities between materno/fetal tolerance and tumor immune escape will provide novel experimental approaches for tumor immuno-therapy.";201932,4;201932,4;FP7-PEOPLE-2011-IIF;/MC-IIF;UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6;FR;;;/SCI;1;0;0;1;0;0 101405;289377;LEGUMEPLUS;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-ITN;FP7;Optimising plant polyphenols in LEGUMES for ruminant nutrition PLUS health PLUS environmental sustainability;2012-01-01;2015-12-31;http://legumeplus.eu/;Europe must face the Grand Challenges of climate change and global warming, which will seriously affect the production of foods, including animal feeds. Tightening supplies of energy, foods and feeds will further impact on food security. Feeding animals in Europe with large quantities of imported soyabeans is not sustainable. ‘Home-grown’ protein sources, such as forage legumes, offer a valuable alternative, but ruminant animals make inefficient use of protein from most forage legumes. LegumePlus proposes to investigate alternative forage legumes, which increase feed use efficiency through their bioactive polyphenols. In addition to tackling such sustainability issues, they will also contribute to livestock health, welfare and reduce environmental emissions. LegumePlus will study the efficacy of bioactive legumes to i) optimise ruminant nutrition, ii) reduce greenhouse gas emissions and iii) improve milk, cheese and meat quality. It will also investigate how bioactive legumes can control parasitic worms in animals. This network will enable integrated multidisciplinary and intersectoral research training. New tools for comparative genomics in plant breeding will be harnessed and exploited to benefit ruminants and the environment. A new generation of agricultural biotechnologists will be trained to work across disciplines and solve sustainability and bioresource issues. Young researchers will acquire a thorough understanding of ruminant nutrition and parasitology, analytical chemistry and plant breeding and excellent training in state-of-the-art and industrially relevant scientific skills. Close collaboration between participants from the public and private sectors will ensure that the training programme will enhance the employability of young researchers and meet employers’ requirements for interdisciplinary and transferrable skills. This will contribute to the EU policy aim of transforming Europe into an eco-efficient, knowledge based bio-economy.;4097981,68;4097981,68;FP7-PEOPLE-2011-ITN;/MC-ITN;THE UNIVERSITY OF READING;UK;"EIDGENOESSISCHES DEPARTEMENT FUER WIRTSCHAFT, BILDUNG UND FORSCHUNG;KOBENHAVNS UNIVERSITET;DELLEY SAMEN UND PFLANZEN AG;NATIONAL INSTITUTE OF AGRICULTURAL BOTANY;WAGENINGEN UNIVERSITY;INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE;TURUN YLIOPISTO";"CH;DK;UK;NL;FR;FI";"/LIF;/SCI";1;0;0;1;0;0 99029;268648;NGG;ONG;FP7-IDEAS-ERC;ERC-AG-LS7;FP7;Next Generation Genetics of Cancer Predisposition;2011-06-01;2016-05-31;;"Unravelling genetic components of human tumor predisposition has contributed significantly to our understanding on molecular basis of cancer, and cancer prevention in the context of hereditary tumor susceptibility is one of the early examples of benefits from genetic disease information. Research into cancer susceptibility is of great importance, and as shown in this proposal Finland provides unique interdisciplinary possibilities to take the field forward. Indeed, in the near future ability to recruit very small groups of patients with a potentially novel cancer susceptibility phenotype will be more relevant than ever. Such materials have been resistant to previous gene identification approaches but lend themselves towards success by exomic and whole genome sequencing. Important discoveries are anticipated in the following fields of research to be conducted under NGG: 1) Identification of rare high-penetrance Mendelian cancer predisposition conditions, and the respective susceptibility genes. One should note that the impact of a gene discovery for basic understanding of key cellular processes is not related to the frequency of the predisposition condition (e.g. RB, LKB1, P53 etc). 2) Identification of moderate penetrance cancer susceptibility genes. Such phenotypes have been difficult to approach with traditional gene identification methods because large pedigrees with multiple affected individuals and few or no phenocopies are not easily identified. Also, the current GWAS approaches are not ideal to detect these loci due to relative rarity of the responsible variants. 3) Characterization of common variants associated with cancer susceptibility.";2483525;2483525;ERC-2010-AdG_20100317;/ERC-AG;HELSINGIN YLIOPISTO;FI;;;"/HCS;/LIF;/MED";1;0;0;1;0;0 94682;254677;WORLDSCIENCE;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IEF;FP7;Worldscience: Scientific Experts in Trans-European Networks (1770-1840);2010-06-01;2012-05-31;;This project focuses on a limited number of highly mobile polyvalent savants -civilians or military- who were invited by the ruling elites of a foreign country to promote scientific-technological policies. The researcher will study the role of these men of science in multidirectional cultural transfer from a comparative perspective. A uniting factor which makes the comparison feasible is achieved through a selection of independent countries where the ruling elites interiorized the notion of decline, “delay” or backwardness and aimed to overcome it by searching inspiration abroad (Spain, Latin American republics, the Ottoman Empire, Russia). The time span includes the period of Enlightenment and the first decades of constitutional regimes. Biographic method and network analysis will be combined with the analysis of discourse in order to examine the representation and self-representation of these savants whose “cosmopolitan” life trajectories -paradoxically?- often combined with their contribution to the building of modern Nation-States. One of the objectives is to examine whether these men constituted not only networks that crossed the borders, but also a universal imagined community. The researcher also aims to analyze the possibilities and limits of cultural transfer, examining the compatibility and incompatibility of practices, standards and values, as well as the appropriation and hybridization of concepts, focusing on broader political and social framework. The multidirectionality of transfer will be stressed, pointing to Extra-European contribution to the Enlightenment. The project will help the researcher acquire new skills: she will use innovative interdisciplinary methodology and develop intercultural communication skills through the collaboration with an international project on Global and World History led by the host institution. Working in the host institution represents a fundamental step for her in order to achieve an independent leading position.;162769;162769;FP7-PEOPLE-2009-IEF;/MC-IEF;UNIVERSITAET POTSDAM;DE;;;"/SCI;/EDU;/ITT";1;0;0;1;0;0 101158;285985;DIABSMART;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IAPP;FP7;Development of a new generation of DIABetic footwear using an integrated approach and SMART materials;2011-11-01;2015-10-31;;"DiaBSmart project aims to generate, transfer and exchange the clinical, academic and production knowledge between the partners to create a new generation of diabetic footwear through a newly developed patient assessment system.The transfer of knowledge(TOK) between various sectors ensures that the need of patients is considered and transferred effectively to product development using a scientific approach.The objectives include:(1) the design and development of an integrated system of DIABetic foot assessment (2) to validate the newly developed system using experimental methods (3) to develop a suitable material to meet the mechanical and clinical requirements (4) to evaluate the mechanical and clinical effectiveness of material choice in reducing the potential risk of foot complications.The Numerical, Experimental and Mathematical Analyses system will integrate all aspects of diabetic footwear including; clinical and biomechanical assessment, material choice and aesthetic design.Proposed interdisciplinary, intersectorial approach is unique and brings together the expertise from research institutions, industry and clinics. TOK between these sectors will ensure the synergy and efficient use of information in patient assessment, monitoring, product development and customisation in an objective manner.This project while enhancing the knowledge base in diabetic assessment; will have a clear impact on new product development leading to both clinical and economic benefits. The products include a new generation of integrated SMART /multi material midsoles and/or orthoses for diabetic footwear.Properties of the materials will be optimised with a view to minimise/ redistribute the pressure and hence the stress on the soft tissue in the critical plantar areas of the foot.Whilst significantly affecting the course of the disease, the products will aim to reduce the risk of limb loss in patients with diabetes,the most frequent cause of non-traumatic lower-limb amputations.";809238;809238;FP7-PEOPLE-2011-IAPP;/MC-IAPP;STAFFORDSHIRE UNIVERSITY;UK;"SALTS HEALTHCARE LTD;TECHNOFOOTBED SL;INDIA DIABETES RESEARCH FOUNDATION;HOCHSCHULE MAGDEBURG-STENDAL";"UK;ES;IN;DE";/IND;1;0;0;1;0;0 102534;279505;MEGA-XUV;ONG;FP7-IDEAS-ERC;ERC-SG-PE3;FP7;Efficient megahertz coherent XUV light source;2012-03-01;2017-02-28;;"'Coherent extreme ultraviolet (XUV) light sources open up new opportunities for science and technology. Promising examples are attosecond metrology, spectroscopic and structural analysis of matter on a nanometer scale, high resolution XUV-microscopy and lithography. The most promising technique for table-top sources is femtosecond laser-driven high-harmonic generation (HHG) in gases. Unfortunately, their XUV photon flux is not sufficient for most applications. This is caused by the low average power of the kHz repetition rate driving lasers (<10 W) and the poor conversion efficiency (<10-6). Following the traditional path of increasing the power, numerous research teams are engineering larger and more complex femtosecond high-power amplifier systems, which are supposed to provide several kilowatts of average power in the next decade. However, it is questionable if such systems can easily serve as tool for further scientific studies with XUV light. The goal of this proposal is the realization of a simpler and more efficient source of high-flux XUV radiation. Instead of amplifying a laser beam to several kW of power and dumping it after the HHG interaction, the generation of high harmonics is placed directly inside the intra-cavity multi-kilowatt beam of a femtosecond laser. Thus, the unconverted light is “recycled”, and the laser medium only needs to compensate for the low losses of the resonator. Achieving passive femtosecond pulse formation at these record-high power levels will require eliminating any destabilizing effects inside the resonator. This appears to be only feasible with ultrafast thin disk lasers, because all key components are used in reflection. Exploiting the scientific opportunities of the resulting table-top multi-MHz coherent XUV light source in various interdisciplinary applications is the second major part of this project. The developed XUV source will be transportable, which will enable the fast implementation of joint measurements.'";1500000;1500000;ERC-2011-StG_20101014;/ERC-SG;UNIVERSITE DE NEUCHATEL;CH;;;"/PSE;/ELM;/NNT";1;0;0;1;0;0 102297;295244;SPORT-BOUND;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IRSES;FP7;Sport across international boundaries: building knowledge through shared understanding;2012-02-01;2015-01-31;;"The establishment of closer international cooperation to share and develop research on the management and coordination of sport is timely and significant. This project aims to provide a platform for exchange and dialogue between Europe and Asia, promoting good practice and the development of interdisciplinary, international networks leading to the dissemination of knowledge about EU law and practice in the sport sector. The objectives of the project include: • establishing an active international community and effective communication channel for the teams to cooperate on global sports management topics • integrating the complementary expertise of the European and Chinese teams to devise best practice case studies and standards to address the multi faceted requirements of managing sports; ensuring a positive, sustainable impact • establishing an EU/China research hub specifically addressing current challenges in sport to operate as a central resource dispensary on research in the area • leveraging the geographical characteristics of the teams to evaluate and disseminate the research outcomes in different regions of the EU and China • Two European Universities and One Chinese University will synchronise their research to propose integrated solutions and examine the effectiveness of current policies in a global context through case studies from the partners. The research teams each have different, but overlapping strengths across the societal, economic and organisational aspects of sport and employ a combination of qualitative and quantitative methodologies. A series of exchange programs and two industry seminars will be organised in order to share, integrate and evaluate the research. The value of this project will be in exploiting the objectives in order to have a wide impact across various sections of European policy. It will create a platform to continue the formation of transnational links to address key current issues and ensure the integrity of sport.";205800;205800;FP7-PEOPLE-2011-IRSES;/MC-IRSES;COVENTRY UNIVERSITY;UK;INSTITUT SUPERIEUR DU COMMERCE DE PARIS;FR;/SCI;1;0;0;1;0;0 100029;293720;METABOSTEM;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-CIG;FP7;METABOLIC CONTROL OF IMMATURE STROMAL CELL BIOLOGY;2011-08-01;2014-07-31;;'A very recent literature claims that metabolic status represents a crucial regulatory mechanism that helps direct stem cells fate. Whereas mainly described on the well characterized hematopoietic stem cells population, such metabolic investigations have been poorly conducted on another key population of adult immature cells that populate the stromal compartment of all tissues, i.e. the mesenchymal stromal/stem cells (MSC). Among them, adipose-derived stromal/stem cells (ASC) have been defined both as multipotent precursors and as supporting cells through their high secretory and immunomodulatory properties. These ASC hallmarks explain their potent regenerative capacities and have prompted clinical studies on their therapeutic potential. However, the mechanisms that govern their plasticity and fate as well as their interactions with other cell populations still remain to be unravelled. Along with ASC, adipose tissue harbours other immature populations whose biology is poorly described. The main objective of this METABOSTEM project is to investigate the role of metabolism in the intrinsic biology and fate of immature stromal populations residing within adipose tissue. Based on neuron-astrocyte and cancer cells models, we hypothesize that supporting cells such as ASC control the surrounding immature populations through a metabolic coupling, representing a new and primitive mechanism by which stromal compartment could control stem cells biology within the niche. This interdisciplinary project will integrate different scientific fields and techniques together such as in situ analysis, metabolic characterisation and stem cell biology, using murine adipose tissue as a working model. The METABOSTEM proposal will hopefully help at a better understanding of the biology of immature stromal cells from adipose tissue, both in physiological and regenerative conditions, and will have larger consequences on the way to manipulate and expand them.';75000;75000;FP7-PEOPLE-2011-CIG;/MC-CIG;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FR;;;/SCI;1;0;0;1;0;0 102216;280032;SMAC;ONG;FP7-IDEAS-ERC;ERC-SG-PE6;FP7;Statistical machine learning for complex biological data;2012-02-01;2018-01-31;;This interdisciplinary project aims to develop new statistical and machine learning approaches to analyze high-dimensional, structured and heterogeneous biological data. We focus on the cases where a relatively small number of samples are characterized by huge quantities of quantitative features, a common situation in large-scale genomic projects, but particularly challenging for statistical inference. In order to overcome the curse of dimension we propose to exploit the particular structures of the data, and encode prior biological knowledge in a unified, mathematically sound, and computationally efficient framework. These methodological development, both theoretical and practical, will be guided by and applied to the inference of predictive models and the detection of predictive factors for prognosis and drug response prediction in cancer.;1496004;1496004;ERC-2011-StG_20101014;/ERC-SG;ASSOCIATION POUR LA RECHERCHE ET LE DEVELOPPEMENT DES METHODES ET PROCESSUS INDUSTRIELS;FR;;;"/PSE;/IPS";1;0;0;1;0;0 102536;283771;METAGESTUREMUSIC;ONG;FP7-IDEAS-ERC;ERC-SG-SH5;FP7;Meta-Gesture Music: Social, Embodied, Interactive Musical Instruments;2012-04-01;2017-03-31;;'The era of recorded music that dominated the 20th century is near its end. Jacques Attali predicted that society would pass from a use of music in 'répétition' (reproduction) to physically engaged acts of 'composition.' Christopher Small coined the term, 'musicking' to refer to all acts of engagement with music, breaking down the barriers between performer and spectator. This interdisciplinary project draws upon 3 complementary research fields to create gestural, interactive musical instruments for both musicians and non-musicians alike. It draws upon Auditory Culture studies to understand the cultural significance of music. It uses User Centered Design (UCD) methods to involve the end user in scenario building and creation of design mock ups. These ideas will be implemented in functional interactive musical instruments that are built and programmed using techniques from the field of New Instruments for Musical Expression (NIME). In this way, the project will explore the deep relationships we as humans have to sound and music. Engaging with music is not just a use of the ears, but an involvement of the whole body, the space around us, and the social situations we are in. Together, this creates 'embodied musical interaction', interaction with music that is physical, situated, social, and participatory. This vision of music opens up the creative process of music and embraces all acts of engagement with music, from selecting, to listening, to dancing, to performing. The cultural perspective will inform the design of interactive instruments that use advanced sensor technologies such as: biosignal sensors detecting muscle tension, accelerometers on iPhones, motion capture systems for free space movement, to topological tracking with GPS. Sophisticated gesture recognition algorithms will be connected to advanced sound synthesis engines. Innovative techniques for correlating gesture to sound will result in engaging, accessible, embodied interactive musical instruments.';1692799,8;1692799,8;ERC-2011-StG_20101124;/ERC-SG;GOLDSMITHS' COLLEGE;UK;;;/SOC;1;0;0;1;0;0 97615;247614;NET4M;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IRSES;FP7;Development of a collaborative network for micro -manufacturing, -assembly and -robotics;2011-03-12;2015-03-11;;"The growing trend toward miniaturization has impacted technologies in virtually every field, from medical and biomedical, automotive, aeronautics and aerospace, IT and telecommunication to other fields such as household appliances, entertainment, sport equipment and manufacturing. Recent market analyses by Nexus forecast a market growth rate of at least 16 % p.a. in the next years (from 12 billions $ 2004 to 25 billion $ 2009). Consequently, a dramatic shift is also occurring within the manufacturing paradigm toward the development of complementary capabilities for producing miniaturized products. This has led to the creation of mesoscale machine tools and robots (mPKM) that are less expensive and more portable than conventional equipment. Furthermore, this trend has led to research efforts on multiscale (micro/meso) levels, bridging the gap between the micro and macro worlds and addressing the limitations of the MEMS and lithographic technologies, not suitable for the production of highly complex MEMS, in which electronic components are integrated with sophisticate mechanical structures, such as moving three-dimensional structures. This proposal wants to address these topics developing a new generation of reconfigurable micro/meso scale robotic handling, positioning and fixturing devices, to be designed and manufactured with the most widespread (and ready to move from academic labs to industrial R&D labs for small series production) micro-manufacturing processes. The micro/meso devices, based on parallel kinematics architectures, will be designed and downsized to reach the limits given by the process technologies, although is foreseen that the limits will be given by the sensor/actuation system. Moreover, the proposal wants to enhance the proposers’ competencies in the micro-manufacturing field, establishing an international network of Research Laboratories in the field of micro-manufacturing, with synergic and interdisciplinary skills.";187200;187200;FP7-PEOPLE-2009-IRSES;/MC-IRSES;CONSIGLIO NAZIONALE DELLE RICERCHE;IT;UNIVERSITE DE FRANCHE-COMTE;FR;"/SCI;/EDU;/ITT";1;0;0;1;0;0 96348;251186;STEMCAM;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IAPP;FP7;A IAPP on the Role of NCAM in Stem Cell Differentiation;2010-09-01;2014-08-31;http://stemcam.biotalentum.eu/;The STEMCAM project is a 4-years training and transfer of knowledge program between two distinguished academic groups in stem cell research, two highly innovative SMEs and a company leader in development of media for stem cell research, to foster long-term industry-academy collaboration and partnership in the field of stem cells research and applications. The scientific and industrial aim of STEMCAM is to study the role of the Neuronal Cell Adhesion Molecule NCAM and related growth factors in the maintenance, survival and differentiation of induced pluripotent stem (iPS) cells towards the neural and myocardial lineage, in comparison with embryonic stem cells. The project will take advantage of very unique and innovative pharmacological tools, the NCAM and growth factor mimetic peptides discovered by ENKAM. To achieve its aim STEMCAM will apply an interdisciplinary approach from cell biology (including innovative in vitro culture using bi- and three dimensional systems), immunocytochemistry, imaging, molecular biology, electrophysiology, to peptide chemistry and chemioinformatics. The project will run via a training and transfer of knowledge program structured to efficiently exploit the expertise and complementarities between the industrial and academic partners to reach the scientific goals of the project and provide high quality intersectorial training for the participating researchers. This is expected to be of high benefit for their individual career development. The STEMCAM project links intersectorial research activities in two very relevant areas of stem cell research, neurogenesis and cardiomyogenesis and will strictly collaborate with the IAPPs INDUSTEM and PARTNERS and the large FP7 IP ESNATS, complementing and expanding with its unique approach their research scope and transfer of knowledge. Thus STEMCAM will significantly contribute to progress of stem cell research in Europe with high potential impact on European competitiveness and regenerative medicine;1489317;1489317;FP7-PEOPLE-2009-IAPP;/MC-IAPP;BIOTALENTUM TUDASFEJLESZTO KFT;HU;"KLINIKUM DER UNIVERSITAET ZU KOELN;UNIVERSITE DE GENEVE;ENKAM PHARMACEUTICALS A/S;STEMCELL Technologies Inc.";"DE;CH;DK;CA";"/SCI;/EDU;/ITT";1;0;0;1;0;0 100629;284085;PASTPLACE;ONG;FP7-IDEAS-ERC;ERC-SG-SH5;FP7;The Past in its Place: Histories of Memory in England and Wales;2012-01-01;2016-12-31;;"This five-year project will explore the ‘history of memory’ in a range of English and Welsh locales from the early medieval period down to the modern era. Drawing on the disciplinary perspectives of literary studies and archaeology, the project will identify and interpret textual and material ‘technologies of remembrance’, including texts, oral traditions, monuments and customary practices. PASTPLACE will transcend the boundaries of periodization and discipline to examine patterns of remembrance, re-imagining and forgetting over the longue durée. Research will be organized in three strands with staggered start-dates, focusing on three types of locale strongly associated with cultural and individual memory. Strand 1 focuses on the history of death, burial and commemoration at a group of English and Welsh cathedrals. Strand 2 explores the interaction of medieval, early modern and modern people with sites of ancient habitation, including Roman settlements, Iron Age hill forts, and prehistoric tombs. Strand 3, ‘Topographies of Memory’, explores the organization of natural and historical landscape features in perceptual frameworks. Research in each strand will centre on six case studies drawn from across southern Britain, with clusterings in the southwest and the Welsh borders. The project’s findings will be disseminated in three co-authored volumes, edited by the PI, under the general title The Past in its Place. Exemplifying a fresh interdisciplinary approach to the history of memory, the project aims to ignite further research both within Britain and overseas. With its cross-period approach, innovative combination of literary and archaeological perspectives and methodologies, and multicultural focus, this timely project addresses challenges at the frontiers of multiple disciplines.";1261624,8;1261624,8;ERC-2011-StG_20101124;/ERC-SG;THE UNIVERSITY OF EXETER;UK;UNIVERSITY OF CHESTER;UK;/SOC;1;0;0;1;0;0 95381;251349;TAYLORMED;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IAPP;FP7;Electrospray-Mediated Delivery of Biological Molecules into Mammalian Cells;2010-08-01;2015-02-28;;This partnership has been created to address the critically poor efficacy of existing treatment strategies to treat lung disease, a major health problem in the EU. The project will research and develop a novel process involving electrospray to deliver biomolecule-based drugs into cells. The action requires intersectorial collaboration between partners with complementary expertise in biological drug delivery, mechanical and manufacturing engineering and microfluidics technologies. The problem will be tackled by researching the parameters that influence electrospray generation and its ability to successfully deliver active biomolecules into cells. The term ‘electrospray’ refers to the process where electrical charges are provided to a fluid in order to generate a very fine spray of the fluid. Applications of electrospray technology include mass spectrometry, chemical deposition and colloid thrusters. Recently, the process has been applied to areas of biology such as protein mass spectrometry, depositing biological material during tissue engineering and the production of protein microarrays. However, the fundamental parameters underlying electrospray formation are poorly understood, limiting full exploitation of the potential of this phenomenon. We have developed a novel electrospray system which we have successfully used to demonstrate a novel application of delivering biological molecules into cells such that they remain functional within the cell. This technology holds substantial potential as a novel drug delivery method. In this interdisciplinary action, we aim to increase understanding of the physical processes involved in electrospray generation, to develop the technology and to determine its potential to deliver of a wide range of biological molecules into cells. The project will significantly advance the area of electrospray-mediated drug delivery with major relevance for pharmaceutical/drug delivery/medical device companies, patients and clinicians in the EU.;962006;962006;FP7-PEOPLE-2009-IAPP;/MC-IAPP;NATIONAL UNIVERSITY OF IRELAND MAYNOOTH;IE;"THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN;THE DOLOMITE CENTRE LIMITED";"IE;UK";"/SCI;/EDU;/ITT";1;0;0;1;0;0 101020;280140;GQEMS;ONG;FP7-IDEAS-ERC;ERC-SG-PE3;FP7;Graphene Quantum Electromechanical Systems;2012-01-01;2016-12-31;;"'The aim of this project is to develop a new class of mechanically tunable quantum devices based on graphene. Adopting an innovative and interdisciplinary approach grounded on both engineering-based microsystem technology and low-temperature solid-state physics, we aim at gaining control over the mechanical and electromechanical properties of graphene nano-membranes and suspended graphene nanostructures, in the low and high strain regime. The main motivation for going in this direction is the expectation that being able to access both the electronic and the mechanical degrees of freedom of graphene will allow to explore new regimes of quantum physics, and lead to potentially important technological applications. Graphene is in fact a unique platform for the development of a new generation of quantum electromechanical systems, not only because of its high carrier mobility, high elasticity and unrivaled material strength, but also because its electronic properties depend sensitively on local strain and mechanical deformations, allowing to envision revolutionary device concepts. This is a timely and highly explorative high-gain/high-risk research project. Its successful accomplishment will set the basis of a novel graphene-based microsystem technology. The project is expected to have an important and far-reaching impact in the fields of nanosystems and graphene physics, not only in terms of potential applications, but also giving an important contribution to the investigation of the fundamental properties of this unique material.'";1797200;1797200;ERC-2011-StG_20101014;/ERC-SG;RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN;DE;;;"/PSE;/ELM;/NNT";1;0;0;1;0;0 100144;294302;LANGEVO;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-CIG;FP7;Cultural and Biological Bases of Language Evolution;2011-09-01;2015-08-31;;"The origins and evolution of human languages remains today one of the most fascinating unresolved puzzles of science and many disciplines are currently working on the subject. Computer scientists have also become involved, trying to program artificial agents in such a way that they are able to self-organize a language-like system from scratch. There are already some successful simulations. They endow agents with language strategies in the form of networks of embodied cognitive functions for producing, comprehending, learning and aligning some aspect of language, for example to express participant roles in events using a case grammar. The present project goes one step further and inquires about the origins of these language strategies and how they can become shared in a population, based on the hypothesis that language strategies form in each individual by the epigenetic recruitment and exaptation of distributed networks, which support the strategies culturally emerging in a population. The project will develop the computational foundations for this ‘recruitment theory of language origins’, engage in simulations and robotic experiments, and validate them from a linguistic and biological point of view. It will look at the genetic bases of language by conducting Genome-wide Association Studies correlating phenotypic variation in linguistic aptitude, particularly for language learning, with genetic markers. At the end of this interdisciplinary project a more encompassing picture of language evolution should begin to emerge, illuminating the cultural, cognitive and genetic factors that have played a role in the origins and evolution of language.";100000;100000;FP7-PEOPLE-2011-CIG;/MC-CIG;UNIVERSIDAD POMPEU FABRA;ES;;;/SCI;1;0;0;1;0;0 99088;269427;STAC;ONG;FP7-IDEAS-ERC;ERC-AG-SH4;FP7;Strategic Conversation;2011-06-01;2017-05-31;;I propose a five year interdisciplinary project that will develop a new, formal and robust model of conversation, drawing from ideas in linguistics, philosophy, computer science and economics. The project brings a state of the art, linguistic theory of discourse interpretation together with a sophisticated view of agent interaction and strategic decision making.;1981318,6;1981318,6;ERC-2010-AdG_20100407;/ERC-AG;UNIVERSITE PAUL SABATIER TOULOUSE III;FR;"HERIOT-WATT UNIVERSITY;THE UNIVERSITY OF EDINBURGH";UK;/MED;1;0;0;1;0;0 100653;267209;DIFERENS;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-COFUND;FP7;Durham International Fellowships for Research and Enterprise;2011-10-01;2016-09-30;;Durham University proposes a high-profile international Fellowship scheme. An entirely new Junior Research Fellowship scheme will be launched, aimed at early career researchers with 2-5 years of postdoctoral experience. These Fellowships will be associated with one of Durham’s eight interdisciplinary Research Institutes to provide a supportive and intellectually challenging research environment. We will expand the existing successful Senior Fellowship programme at the Institute of Advanced Study to encompass Senior Fellowships at the other Institutes and introduce a new Senior Fellowship programme aimed at industrialists and policy-makers. All Fellows will retain an association with their Institute after the end of their Fellowship.;9912558;3965023,2;FP7-PEOPLE-2010-COFUND;/MC-COFUND;UNIVERSITY OF DURHAM;UK;;;"/SOC;/COO;/NET";1;0;0;1;0;0 95460;255264;CPAF;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IEF;FP7;Calcium Propagation in Atrial Fibrillation;2010-03-01;2012-02-29;;Synchronized release of Ca2\ from the internal Ca2\ store of cardiac myocytes, the sarcoplasmic reticulum, is essential for a normal heart beat. This is obtained through a sophisticated subcellular organization, the dyad. In dyads, a cluster of release channels in the sarcoplasmic reticulum, ryanodine receptors or RyRs, face Ca2\ channels in the cell membrane, the dihydropyrydine receptors or DHPRs. DHPRs provide the Ca2\ influx that triggers opening of RyR. Ca2\ release can also propagate between RyR, leading to Ca2\ waves that can initiate arrhythmias. We hypothesize that RyR that are not within dyads have different properties that may facilitate wave-like propagation and arrhythmias. The objectives are (1) to identify and characterize RyR located between dyads in the sarcomeric space in healthy myocytes (2) to establish whether altered organization and properties of RyRs in chronic atrial fibrillation (AF) contribute to the contractile dysfunction and arrhythmia in AF. My stay in the host lab will provide a clinical and translational perspective to my current knowledge enhancing the potential impact of my research. An interdisciplinary approach for imaging of RyR with access to novel microscopic techniques in the Molecular engineering department and tools for image analysis with the Medical Imaging Center and ESAT will enhance my technological expertise.;166800;166800;FP7-PEOPLE-2009-IEF;/MC-IEF;KATHOLIEKE UNIVERSITEIT LEUVEN;BE;;;"/SCI;/EDU;/ITT";1;0;0;1;0;0 98531;259152;CODAMODA;ONG;FP7-IDEAS-ERC;ERC-SG-PE6;FP7;Controlling Data Movement in the Digital Age;2011-04-01;2017-03-31;;"Nowadays human intellectual product is increasingly produced and disseminated solely in digital form. The capability of digital data for effortless reproduction and transfer has lead to a true revolution that impacts every aspect of human creativity. Nevertheless, as with every technological revolution, this digital media revolution comes with a dark side that, if left unaddressed, it will limit its impact and may counter its potential advantages. In particular, the way we produce and disseminate digital content today does not lend itself to controlling the way data move and change. It turns out that the power of being digital can be a double-edged sword: the ease of production, dissemination and editing also implies the ease of misappropriation, plagiarism and improper modification. To counter the above problems, the proposed research activity will focus on the development of a new generation of enabling cryptographic technologies that have the power to facilitate the appropriate controls for data movement. Using the techniques developed in this project it will be feasible to build digital content distribution systems where content producers will have the full possible control on the dissemination of their intellectual product, while at the same time the rights of the end-users in terms of privacy and fair use can be preserved. The PI is uniquely qualified to carry out the proposed research activity as he has extensive prior experience in making innovations in the area of digital content distribution as well as in the management of research projects. As part of the project activities, the PI will establish the CODAMODA laboratory in the University of Athens and will seek opportunities for technology transfer and interdisciplinary work with the legal science community.";1212959,74;1212959,74;ERC-2010-StG_20091028;/ERC-SG;ETHNIKO KAI KAPODISTRIAKO PANEPISTIMIO ATHINON;EL;;;"/PSE;/IPS";1;0;0;1;0;0 103459;302421;IAfBG;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IIF;FP7;Integration of Analyses among fMRI, Biophysical Models and Genetic Data;2012-10-01;2014-09-30;;"This project is interdisciplinary in character with three background topics. (1) Functional magnetic resonance imaging (fMRI), which has become an important technique in the study of the cognitive functions of the brain. This topic also has important applications in the routine diagnosis and prognosis of thoracic surgery and mental diseases. (2) Bioinformatics, which has developed into a key approach in the life sciences, relating molecular data to a number of genetic diseases. (3) Biophysical mathematical models, such as the leaky integrate-and-fire neuron, the Hodgkin-Hulexy model, neural mass models and the neural field equation. These have been utilized to study neuronal activities and functions at the cell and tissue level for many years. The project will combine the three background topics, and is aimed towards the integration of data and models. It will establish a framework composed of modelling, mathematical analysis and statistical inference. The ultimate aim is the integration of fMRI, biophysical models and genetic data. This will involve modelling and mathematical analysis to understand the underlying mechanisms due to the intrinsic complexity and noise of biological systems. The specific problems we intend to solve are: (1) Integration of EEG-fMRI data and a neuronal network model; (2) Integration of fMRI and genetic data; (3) An fMRI data analysis, towards diagnosing mental disorders; (4) Modelling and mathematic analysis. The main goal of the project is to gain new insights into some mental disorders and, on the way, develop mathematical models and theory that can explain the observed phenomena. The significance of our findings for social and economic impacts should be considerable since the project will address fundamental issues related to the daily life of human beings. It will take advantage of the quantity and quality of data that are now available and the power of modern computers and mathematical techniques.";278807,4;278807,4;FP7-PEOPLE-2011-IIF;/MC-IIF;THE UNIVERSITY OF WARWICK;UK;;;/SCI;1;0;0;1;0;0 100812;282105;lec&lip2invade;ONG;FP7-IDEAS-ERC;ERC-SG-LS3;FP7;The interactions of the Pseudomonas aeruginosa lectins LecA and LecB with glycosphingolipids result in membrane invagination, signaling and cellular uptake of the bacterium;2011-12-01;2016-11-30;;"Pseudomonas aeruginosa has emerged as a major opportunistic pathogen during the past century. The invasion of host cells plays a fundamental role in the pathogenesis of this bacterium. As clinically important antibiotic resistance of P. aeruginosa continues to increase, the identification of host as well as microbial factors essential for P. aeruginosa uptake may lead to new drug targets. Our highly ambitious and interdisciplinary research project at the interface of biology, chemistry and physics aims at describing the molecular mechanism of the internalization of P. aeruginosa in non-phagocytic cells. Based on novel concepts that we have established for some bacterial toxins and animal viruses, we hypothesize that specific interactions of the P. aeruginosa lectins LecA and LecB with distinct glycosphingolipids exposed at the host cell surface lead to formation of plasma membrane invaginations, activation and recruitment of signaling molecules, cytoskeleton remodeling and cellular uptake of the bacterium. In order to acquire highly complementary results and to ensure the maximal outcome, we will perform our studies on diverse animal cells and various membrane model systems in combination with super resolution imaging techniques, biochemical and screening approaches. For the in vitro reconstitution of bacterial invasion, we will develop a unique platform for membrane nanoscopy based on planar pore-suspending membrane systems of different complexity (e.g. pore-suspending plasma membrane sheets and synthetic lipid bilayers). We expect to be able to identify key factors of bacterial uptake and small molecule inhibitors towards them in order to develop new therapies against the pathogenesis of P. aeruginosa infections.";1436400;1436400;ERC-2011-StG_20101109;/ERC-SG;ALBERT-LUDWIGS-UNIVERSITAET FREIBURG;DE;;;"/BIO;/LIF";1;0;0;1;0;0 95454;252759;BAHAMAS;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IEF;FP7;Biological patinA for arcHaeological and Artistic Metal ArtefactS;2010-06-01;2012-05-31;;The nature of the corrosion products present on the surface of artistic and archaeological metal artefacts is intrinsically related to the environmental context (atmospheric or burial). In order to effectively protect and inhibit the corrosion of such metal objects, the practices adopted should take into account the nature of the patina and its corrosion behaviour. However, the treatments so far employed are organic protective coatings, which do not consider the difference in terms of patina composition and corrosion products stability and simply create a barrier against aggressive environments in a non-selective way. A multidisciplinary project BAHAMAS is here proposed for developing an alternative biological treatment as a novel approach for the conservation-restoration of metal artefacts. The research activity aims at chemically and specifically modifying existing corrosion products into more stable and less soluble compounds while maintaining the surface’s physical appearance. Some species of fungi have been already reported for their ability to transform metal compounds into metal oxalates, which are known to be insoluble and high protective compounds towards corrosion. Thus, the participants will exploit this potential for the transformation of existing corrosion patinas into metal oxalates. Some promising results have been obtained after a first attempt on bronze standards with copper hydroxysulphates and copper hydroxychlorides patinas. The research work will investigate the formation mechanisms and adhesion properties of the newly formed metal oxalates on different metal substrates (copper, iron and silver), which are frequently found in cultural heritage artworks. The collaboration between the Swiss National Museums, the University of Neuchâtel and the researcher will allow the creation of a unique interdisciplinary team and will represent a key aspect for the accomplishment of this innovative research issue in the field of conservation science.;172565,2;172565,2;FP7-PEOPLE-2009-IEF;/MC-IEF;Schweizerisches Nationalmuseum;CH;;;"/SCI;/EDU;/ITT";1;0;0;1;0;0 99445;269251;PRORES;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-IRSES;FP7;Pro-ecological restructuring for job;2011-06-15;2015-06-14;;"The objective of PRORES project is transfer of knowledge in the field of restructuring from three perspectives: economic, ecological and social development. That is why four well prepared Universities from Ukraine, Lithuania and Poland were chosen to carried out the activity. Special attention in the project is given to early stage researchers. Due to project they will take an extensive training in hosting countries. Acquiring knowledge on these perspectives will allow gaining skills necessary to more efficient solving of restructuring problems in European and local markets. Even if PRORES project concerns mobility as a primary objective, the interdisciplinary research is also an important part. The project makes environmental issues central to research on organisational restructuring, stressing the ecological and the social issues. Basic methodology that will be used in project will be a “case study” covering selected companies in project partner countries. The results of the research, as a form of new knowledge, will be disseminated amongst different stakeholders of pro-ecological restructuring. Currently, the project’s topic is of importance for several reasons. Firstly, in the context of the current global financial crisis organisational restructuring processes are widespread across Europe and are especially painful for workers selected for redundancy and their communities. Secondly, the ecological perspective in research is absent. Thirdly, this issue is especially urgent because of the imperatives of climate change and the EU policies aimed at securing a transition to a low carbon economy in both the EU and wider Europe, as Europe 2020: A European strategy for smart, sustainable and inclusive growth. Fourthly, project’s partners perfectly fit for implementing and strengthening European Neighbourhood Policy. Moreover, Ukraine is a very important EU neighbour from not only economic but also social and political perspective.";670700;670700;FP7-PEOPLE-2010-IRSES;/MC-IRSES;UNIWERSYTET SZCZECINSKI;PL;VILNIAUS UNIVERSITETAS;LT;"/EMP;/SOC";1;0;0;1;0;0 103545;296526;INTFOP;ONG;FP7-JTI;JTI-CS-2011-1-SAGE-04-009;FP7;Integrating Forging and Process Simulation for turbine disks;2011-10-01;2014-09-30;;"'The objective of this project is the implementation of an integrated simulation chain including pre material characteristics, thermo-mechanical processing (forging and heat treatment) and assessment of microstructure and functional properties for aerospace turbine components. The integration of different computational results within an interdisciplinary and intercompany design-chain is a challenging task. A fully integrated simulation chain along the supply chain will give unique benefit for product development with respect to time, cost, and quality. This allows an optimization of the forgings in respect of weight, efficiency and CO2 reduction. Böhler Schmiedetechnik GmbH & Co KG (BSTG) has developed a model for determining the microstructure (e.g. local grain size distribution in a component) from forging and heat treatment simulations. This model is in daily use for thermo-mechanical process design and optimization of turbine disks. In past, recent and future R&D projects, Böhler Schmiedetechnik has developed models for determining the local functional properties depending on the microstructure. In a further step, aiming to the topic of this proposal, the simulation chain is to be integrated into an industrialized useful format, target-aimed to customer needs. Suitable strategies and methods for integration of the pre-material characteristics have to be assessed. The quality of the existing models has to be evaluated together with the customer. Comprehensive statistic investigations work is necessary in order to make the usage of the simulated data possible at the customer. Detailed investigations have to be executed to improve and/or generate functional properties models like yield stress, low cycle fatigue and creep models. Interfaces have to be defined and generated. A validation work has to be examined with forged LPT (low pressure turbine) demonstrator disks which show the effectiveness and model capabilities.'";365000;182500;SP1-JTI-CS-2011-01;/JTI-CS;VOESTALPINE BOHLER AEROSPACE GMBH & CO KG;AT;VOESTALPINE BOHLER EDELSTAHL GMBH &CO KG;AT;/SCI;1;0;0;1;0;0 101547;283950;SES-LINK;ONG;FP7-IDEAS-ERC;ERC-SG-SH3;FP7;The nature of social-ecological linkages and their implication for the resilience of human-environment systems;2012-02-01;2017-01-31;;The behaviour of social-ecological systems (SES) is determined by the interactions between actors, institutions and the resource systems they govern and depend on. The resulting social-ecological linkages and feedback loops determine a system’s resilience, i.e. its capacity to cope with and adapt to change. Understanding the dynamic coupling of human and natural systems has thus emerged as a major focus of international efforts to address challenges such as climate change and the sustainable use of natural resources. However, basic information and understanding of the resilience and dynamics of coupled SES is still lacking. The proposed research will advance the conceptual and empirical basis of resilience and our understanding of the dynamics of SESs by systematically investigating social-ecological linkages and their impact on system resilience using theoretical and empirically- based simulation modelling. The analysis will be based on four diagnostic case studies from water, marine ecosystem and land management iteratively combined with theoretical modelling of stylized cases. It will apply and further develop an ontological SES framework that facilitates interdisciplinary analysis and comparison of SES. As there is no single theory and method for the study of SESs we will develop new conceptual perspectives by combining insights and methods from various fields. The results of the case and linkage-specific investigations will be synthesized to identify generalities and patterns among types of linkages and their impacts on resilience. The consequences of these insights for natural resources management will be assessed. The research is innovative in that it takes both ecological and social dynamics of SES into account using formal methods to achieve a systematic and rigorous assessment of factors determining resilience. The ontological framework and integration of concepts and modelling methods will open new opportunities for research of the sustainability of SES.;1284748,16;1284748,16;ERC-2011-StG_20101124;/ERC-SG;STOCKHOLMS UNIVERSITET;SE;;;/SOC;1;0;0;1;0;0 101439;291602;XLASERS;ONG;FP7-IDEAS-ERC;ERC-AG-PE3;FP7;X-RAY LASERS, PHOTON SCIENCE, AND STRUCTURAL BIOLOGY;2011-12-01;2016-11-30;;Theory predicts that with an ultra-short and very bright coherent X-ray pulse, a single diffraction pattern may be recorded from a large macromolecule, a virus, or a cell before the sample explodes and turns into a plasma. The over-sampled diffraction pattern permits phase retrieval and hence structure determination. The first free-electron lasers (FELs) capable to deliver ultra bright and very short X-ray pulses for such experiments have recently started operations. These are the most brilliant sources of X-rays to date, exceeding the peak brilliance of conventional synchrotrons by a factor of 10 billion. In the duration of a single flash, the beam focused to a micron-sized spot has the same power density as all the sunlight hitting the Earth, focused to a millimetre square. The interaction of an intense X-ray pulse with matter is profoundly different from that of an optical pulse. A necessary goal of the programme is to explore photon-material interactions in strong X-ray fields. Our aim in structural biology is to step beyond conventional damage limits and develop the science and technology required to enable high-resolution studies of single biological objects near the physical limits of imaging. Eligible targets include single virus particles, organelles, cells, nanocrystals, and isolated macromolecules. A particular aim of the planned work is to obtain high-resolution structures for giant viruses. The challenges engage an interdisciplinary approach, drawing upon structural sciences, biology, atomic and plasma physics, optics and mathematics. The potential for breakthrough science is great with impact not only in biology or physics but wherever dynamic structural information with high spatial and temporal resolution is valuable. The overall relevance of the programme extends beyond basic science, to technologies of essential importance to a future Europe.;2500000;2500000;ERC-2011-ADG_20110209;/ERC-AG;UPPSALA UNIVERSITET;SE;;;"/PSE;/ELM;/NNT";1;0;0;1;0;0 100127;288701;CoolEmAll;ONG;FP7-ICT;ICT-2011.6.2;FP7;Platform for optimising the design and operation of modular configurable IT infrastructures and facilities with resource-efficient cooling;2011-10-01;2014-03-31;;"An increasingly important factor in the construction of data centres is the use of modular building blocks as opposed to bespoke facilities. This modular approach is becoming popular due to lower costs, shorter building times, and flexibility of design. However, as this flexibility gives a broad spectrum of configurations, there is significant scope for analysing the energy efficiency aspects of the modular approach. In order to have a deep insight into the total energy consumption of both large data centres and smaller facilities more research is needed to determine how intrinsically efficient the approach is.Thus the main goal of CoolEmAll is to provide advanced planning and optimisation tools for modular data centre environments. Once developed, these tools should help to minimise the energy consumption, and consequently the CO2 emissions of the IT infrastructure with related facilities. This will be achieved by:(i) Design of diverse types of computing building blocks (ComputeBox Blueprints) precisely defined by energy efficiency metrics;(ii) Development of simulation, visualization and decision support toolkit (SVD Toolkit) that will enable analysis and optimisation of IT infrastructures built of these building blocks;Both activities will include three important aspects when considering the energy efficiency of modular data centres: cooling techniques, applications properties, and management policies.To achieve these goals CoolEmAll will follow the interdisciplinary approach using project partners' expertise and technologies in relevant areas. Validation of results will be done by both real-life and simulation studies. The former will be possible thanks to the small scale real prototype of ComputeBox with fine-grained monitoring. Simulation studies will allow analysing and optimising energy efficiency in specific scenarios and designing ComputeBox Blueprints leading to potential energy savings of 10-50% depending on a specific case.";3589460;2626438;FP7-ICT-2011-7;/CP;INSTYTUT CHEMII BIOORGANICZNEJ POLSKIEJ AKADEMII NAUK;PL;"451 RESEARCH (UK) LIMITED;FUNDACIO INSTITUT DE RECERCA DE L'ENERGIA DE CATALUNYA;ATOS SPAIN SA;CHRISTMANN INFORMATIONSTECHNIK + MEDIEN GMBH & CO KG;UNIVERSITAET STUTTGART;UNIVERSITE PAUL SABATIER TOULOUSE III";"UK;ES;DE;FR";/EST;1;0;0;1;0;0 102023;291349;PHOTBOTS;ONG;FP7-IDEAS-ERC;ERC-AG-PE2;FP7;Nano Photonics-Based Micro Robotics;2012-01-01;2017-12-31;;"The general goal is to bring together different fields of research in order to create a new research area of photonic micro robotics. That is to create, study, and implement truly microscopic structures with nano scale accuracy that can perform robotic tasks and that are entirely powered and controlled by light. This idea brings immense challenges both from the point of view of the physics involved as well as the chemistry needed to create the appropriate materials, but if successful can also have a huge impact. To achieve this, we will combine our expertise on complex photonic materials and direct laser writing, to create micro structured patterns in liquid crystal elastomers, which are rubber-like polymers with liquid crystalline properties that can be triggered with light. In our view, this opens up a new strategy to create robots of various kinds, on a truly micrometer length scale. That is, micro robots that can swim, walk, or crawl, and when at destination perform specific tasks, controlled and driven by light. This proposal, in the first instance, deals with fundamental, curiosity-driven research and wishes to address the wealth of physics and chemistry that arises when combining nano photonics with micro robotics. Having said that, the range of potential applications is very broad. Our photonic micro robots would be able to penetrate otherwise difficult to access environments and perform tasks such as sensing or sampling. They could be made in large quantities which means they could also be put into action collectively in swarms (using mechanical and/or optical interaction between the individual robots). The project is truly interdisciplinary, which makes it very challenging but also exciting. The photonic micro robotic structures will be created by bringing together concepts from physics and chemistry, while the inspiration for designs comes partly from biology and potential applications can be foreseen in medicine.";2200000;2200000;ERC-2011-ADG_20110209;/ERC-AG;LABORATORIO EUROPEO DI SPETTROSCOPIE NON LINEARI;IT;;;"/PSE;/SCI";1;0;0;1;0;0 101469;284231;HIPODEMA;ONG;FP7-IDEAS-ERC;ERC-SG-SH6;FP7;FROM DECISIONISM TO RATIONAL CHOICE: A History of Political Decision-Making in the 20th Century;2011-12-01;2016-11-30;;"Historians have good reasons to be highly suspicious of the “rational choice” methodologies that hold sway in economics, political science or sociology and that find a new lease on life today with the rise of the cognitive sciences. On the other hand, researchers using these methodologies show usually very little interest in history. The result is that we know very little about the historical development of “rational choice” as a way to define rationality in action, while this intellectual paradigm has become pervasive and reshaped the way we do science and the way we think about politics. This project will follow the problem of decision-making through the 20th century and weave into a single historical narrative its different disciplinary formulations. It starts with a puzzle: while the “decisionist” critiques of legality of the 1920s associated the decision with an anti-rationalist vision of politics, this notion gradually morphed into the epitome of “rational choice” after 1945. How did this transformation occur? The project will reconstruct this shift from a paradigm in which Law was the instrument that would make political decisions rational, to another in which the power of rationalization was vested in Science. It asks how the post-1945 efforts at specifying conditions of rationality for political decisions changed the meaning of “rationality.” It connects these developments to the interdisciplinary set of “decision sciences” that emerged in the 1950s around issues of strategic and political behavior and spawned our contemporary instruments of “conflict-resolution” or automated models of decision-making. The project suggests that “rationality” in political decision-making is not a transcendental norm, but a historically contingent benchmark dependent on its technical instrumentations. Democratizing political decision-making, then, means opening these models and instruments of rationalization to scholarly debate and public scrutiny.";628004;628004;ERC-2011-StG_20101124;/ERC-SG;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FR;;;"/SCI;/SOC";1;0;0;1;0;0 95459;255173;OOCYTE ASYMMETRY;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IEF;FP7;Quantitative dynamic analysis of homologous chromosome segregation and its coordination with the asymmetric meiotic division in live mouse oocytes;2010-04-01;2012-03-31;;Cell division is a fundamental biological process: faithful chromosome segregation is important to maintain genome stability. The first meiotic division is a unique type of chromosome segregation for two main reasons. First, it segregates homologous chromosome pairs rather than sister chromatids, as it occurs in mitosis. Second, the chromosomes are segregated only when the meiotic spindle has been positioned at the cortex of the oocyte. This division is extremely asymmetric to preserve the stored nutrients for the early embryo. Errors in segregation of chromosomes during meiotic divisions can result in the generation of aneuploid embryos such as Down syndrome. As in mitosis, chromosome missegregation during meiotic division is prevented by the spindle assembly checkpoint that monitors correct attachment to microtubules until chromosomes are bioriented. However, the spatio-temporal coordination between chromosome segregation and spindle positioning is poorly understood. The aim of my project, in Dr. Ellenberg’s group, is to characterize cellular and molecular mechanisms that coordinate accurate chromosome segregation with spindle relocation. First, I will characterize the functional dynamics of chromosome segregation in coordination with the spindle relocation by real time imaging in live mouse oocytes. Second, I will use these imaging assays to investigate its mechanism by perturbation of candidate gene function as well as interfering with cellular components with small molecule inhibitors. Dr. Ellenberg’s group is part of EMBL, a dynamic and stimulating international institute, which offers great potential for interdisciplinary collaborations and training. In this project, I will be able to use my skills concerning mouse oocytes, and at the same time, acquire new expertise in advanced imaging and computerized image processing. I deem this a unique opportunity to address key questions of mouse oocyte research and to further broaden my career as a scientist.;161161;161161;FP7-PEOPLE-2009-IEF;/MC-IEF;EUROPEAN MOLECULAR BIOLOGY LABORATORY;DE;;;"/SCI;/EDU;/ITT";1;0;0;1;0;0 98451;269202;HEMOW;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-IRSES;FP7;Health Monitoring of Offshore Wind Farms;2011-04-01;2015-03-31;http://www.hemow.eu/;Offshore wind farm health monitoring and maintenance are major challenges for renewable energy generation due to large scale, high cost and extreme environments. The development of faults in the tower or blades can cause serious secondary damage to the whole wind turbine system if prompt repair action is not taken and can lead to catastrophic failure. Although numerous techniques are being developed worldwide to monitor changes in specific parts of structure, the wide variety of materials and techniques involved means that skills and expertise are disparate and disconnected. For this new interdisciplinary area, this project will bring well recognised scientific institutions and researchers with complementary research experience and skills together, in the context of a collaborative scheme of research exchanges and networking. The proposed project is endorsed by 5 institutions, 2 EU partners and research groups in China and India, agreeing for a common exchange program built around the work packages to develop methods, models, systems and ICT tools for health monitoring and maintenance of offshore wind turbines. The members of the project consortium will provide complementary knowledge and strengths, as they have all carried out leading research in the area of non-destructive evaluation, structural health monitoring, communications and networks, information management, etc. The complementary capabilities have been drawn out in accordance with a joint research vision, commonly shared by the partners at the moment of writing the proposal. The project will consist of targeted research project undertaken by key individual researchers, supplemented and supported by PhD students, researchers and professors. The exchanges will enable the reciprocal transfer of knowledge between the members of the consortium and will be deployed by a set of various activities (visits, training in laboratories, lectures, workshops, seminars) open also to external stakeholders.;241500;241500;FP7-PEOPLE-2010-IRSES;/MC-IRSES;UNIVERSITY OF NEWCASTLE UPON TYNE;UK;ZACHODNIOPOMORSKI UNIWERSYTET TECHNOLOGICZNY W SZCZECINIE;PL;"/EMP;/SOC";1;0;0;1;0;0 100358;279068;NESS;ONG;FP7-IDEAS-ERC;ERC-SG-PE6;FP7;"Listening to the Future: Next-generation Sound Synthesis through Simulation";2012-01-01;2016-12-31;;"This proposal is concerned with simulation-based approaches to sound synthesis, in the interest of generating very high quality synthetic sound of a natural acoustic character—partly to emulate real instruments, but also to explore classes of sounds which cannot be produced using conventional synthesis methods, or acoustic instruments. A further goal is to introduce such physical modelling synthesis methods definitively into the world of electronic music, virtual environments, and to the greater public. Target systems to be studied and simulated include: highly nonlinear acoustic systems (brass instruments, and percussion based on plate and shell vibration; electromechanical instruments; full 3D acoustic spaces; embedding of instruments within 3D spaces in order to achieve fully virtual and spatialized audio; and finally modular connections of systems in order to allow the eventual user, a composer, an instrument design environment. Such complex systems, including strong nonlinear effects, have never before seen a rigorous exploration from a numerical synthesis perspective. This proposed project is of an interdisciplinary nature, and rooted in music, numerical analysis, time-domain simulation, and high-performance computing. Work will be carried out at various levels: a) theoretical work and time domain algorithm design, with special attention paid to the appropriate choice of model, efficiency and real time operation, and various issues critical in audio, including: adequate perceptual rendering of system responses at audio sample rates; aliasing; robust algorithm design, ensuring numerical stability under highly nonlinear conditions; and modular constructions. b) large-scale parallel implementations on multicore processors and general purpose graphics processing units (GPGPUs), and c) experimental testing through collaborative work with established composers of electronic music, leading to performances original multichanel and fully synthetic music.";1477477;1477477;ERC-2011-StG_20101014;/ERC-SG;THE UNIVERSITY OF EDINBURGH;UK;;;"/PSE;/IPS";1;0;0;1;0;0 98844;273867;NPCquant;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-IEF;FP7;Investigation of human nucleoporins stoichiometry and intracellular distribution by quantitative mass spectrometry;2012-04-01;2014-03-31;;The nuclear pore complex (NPC) is one of the most intricate multi-protein assemblies found in eukaryotic cells encompassing ~30 different components called nucleoporins (Nups). The structural determination of the NPC represents a major challenge due to its size and location in the nuclear envelope. Accurate quantitative data on NPC composition that are required to generate structural models at atomic resolution are currently lacking. Here, I propose to apply targeted mass spectrometry to study the stoichiometry and intracellular distribution of the human NPC components. For this purpose, I will establish an assay based on selected reaction monitoring (SRM) experiments that will allow the absolute quantitation of Nups in different cell compartments. The assay will be used to systematically analyze the effect of Nup perturbation on NPC composition by screening cell lines where single Nups are depleted by gene silencing. The compositional analysis of the gene silencing phenotypes will provide the base for complementary structural investigations performed using cryo-electron tomography. The integration of proteomic and structural data will provide accurate information on the stoichiometry and spatial arrangement of Nups within NPCs. In addition, by mapping the intracellular distribution of Nups, it will be possible to gain insights into their functional roles beyond transport. The multidisciplinary approach that will be developed has the potential to pave the way towards the integration of quantitative proteomic technologies in structural studies of other cellular substructures. This fellowship will give me the opportunity to lead an ambitious project at the interface between proteomics and structural biology, and to work in a collaborative interdisciplinary environment. The scientific and complementary skills I will acquire and the opportunity to work in a leading European institution will be fundamental for my development towards an independent scientific career.;162742,4;162742,4;FP7-PEOPLE-2010-IEF;/MC-IEF;EUROPEAN MOLECULAR BIOLOGY LABORATORY;DE;;;"/EMP;/EDU;/NET";1;0;0;1;0;0 102295;295180;MAGNONMAG;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IRSES;FP7;Magnetic order induced in nonmagnetic solids;2012-04-01;2016-03-31;;Our aim is to establish long lasting collaboration in the frames of a research program the goal of which is to develop novel methods of control and manipulation of the magnetic degree of freedom in nominally nonmagnetic materials, in view of their potential for nanotechnology and nanoscience. The principal objective of the MagNonMag project is to bring together leading research groups in the field of nanomagnetism and establish an interdisciplinary training ground for both early stage researchers and experienced researches, enhancing the information partnership between theoretical and experimental research groups working in physics, chemistry, material science, and nanotechnology. The project is focused on nanomagnetism – magnetism shown by some materials on a nanoscale even if magnetically inert in the bulk – a novel physical effect with a potential for the emerging spintronics technology. The MagNonMag project will study the possibility to control magnetism by various means such as introducing sp impurities and defects in nonmagnetic materials through ion bombardment, fluorination, and transmutation doping. The objects under investigation are IV group elements with the emphasis on graphite/graphene systems. Induced magnetism phenomena studied in this project have a potential to provide new effects and functionalities which are highly desirable and of great technological and economic relevance. The synergy of the scientific strength of the Russian Academy Institutes with the technological and analytical potential in the research groups in EU (Sweden, Spain, Italy) and Australia provides a valuable opportunity to study and understand novel phenomenon of induced nanomagnetism which is promising for nanotechnology applications.;549900;524700;FP7-PEOPLE-2011-IRSES;/MC-IRSES;LAPPEENRANNAN TEKNILLINEN YLIOPISTO;FI;"Asociacion - Centro de Investigacion Cooperativa en Nanociencias - CIC NANOGUNE;UNIVERSITA DEGLI STUDI DI PARMA;UMEA UNIVERSITET";"ES;IT;SE";/SCI;1;0;0;1;0;0 98154;269725;PHIC;ONG;FP7-IDEAS-ERC;ERC-AG-SH5;FP7;Philosophy in Context : Arabic and Syriac manuscripts transmission in the Mediterranean World;2011-03-01;2016-02-29;;"Philosophy in Context : Arabic and Syriac manuscript transmissions in the Mediterranean (PhiC) This project aims to solve two major difficulties in research in the history of philosophy: 1) understanding the conditions of the reception and the transmission in the Mediterranean World of philosophy of Greek tradition in the Arabic and Syriac languages; 2) discovering the numerous works buried in libraries in a systematic way, instead of by chance. Thanks to a methodical pooling of the information given in the catalogs of manuscripts and, much more, to the systematic examination of the collections, we will be able not only to identify new texts but also get all kinds of information about the places and the institutions where the texts circulated, their copyists, sponsors, readers, etc. It will thus be finally possible to get a clear idea of how the products of pure reason were welcomed in Islam, and of the motivations of the collectors of manuscripts in Europe since the Renaissance (was it to satisfy the needs of scholarship, to translate the texts or to provide direct inspiration for creative thinking?). This work will be based on the cross-information allowed by the ABJAD database, that will be operational within the project itself. This project thus requires a strongly interdisciplinary approach, combining a thourough knowledge in the history of philosophy, philology, codicology and computer science.";2495315,81;2495315,81;ERC-2010-AdG_20100407;/ERC-AG;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FR;;;/SOC;1;0;0;1;0;0 100787;283597;MULTITASK;ONG;FP7-IDEAS-ERC;ERC-SG-SH4;FP7;Towards safe and productive human multitasking;2011-11-01;2016-10-31;;"People show a strong inclination for multitasking: they use multiple devices while driving a car, students do homework while sending text-messages and watching television, and office workers rapidly switch from one task to another. It is crucial to understand the role of multitasking in modern society, whether in terms of set-ting legal limits to multitasking in cases where it leads to unacceptable risks, or designing work situations in which productivity is supported or security is maintained. The goal of this project is to understand what circumstances change a person from an effective multitasker into one overwhelmed by too many demands, and to design countermeasures to keep people in control. A strong interdisciplinary research program in this area is necessary, because improper multitasking can lead to increased risks, loss of productivity and even long-term decrements in cognitive abilities. To investigate these questions we have developed two new groundbreaking methods. The first is the threaded cognition computational model of multitasking. Threaded cognition predicts when and how tasks interfere, by simulating the cognitive processes in the mind. The second is a new method highlighting the areas of interference. This done by using threaded cognition to analyze fMRI neuroimaging data, mapping functional units in the model onto brain areas. The new challenge is to use both methods to understand and predict how people select tasks for multitasking. The unique combination of methods is expected to result in fundamental knowledge on identifying the mechanisms that determine human task decisions, and in under-standing how sequences of such decisions can lead to multitasking situations with dangerous cognitive over-load or productivity dead-ends. Understanding the cognitive mechanisms of task selection in multitasking can be crucially important in designing multitasking environments that improve productivity and safety in-stead of thwarting it.";1434574;1434574;ERC-2011-StG_20101124;/ERC-SG;RIJKSUNIVERSITEIT GRONINGEN;NL;;;/SOC;1;0;0;1;0;0 100673;284340;LUPE;ONG;FP7-IDEAS-ERC;ERC-SG-SH6;FP7;Sailing into Modernity: Comparative Perspectives on the Sixteenth and Seventeenth Century European Economic Transition;2012-01-01;2014-12-31;;This research project analyses the economic transition in Early Modern Europe through an innovative and interdisciplinary approach that will employ tools from legal, economic and social history for the comparative analysis of the legal position and the economic treatment of sailors active in the Mediterranean. Since Fernand Braudel coined the expression ‘invasion of the northerners’, the subject of how English and Dutch shipping overtook local Mediterranean powers has been a classic topic of economic history. But due to the poor survival of traditional economic documentation for this period, we still know little about the details of how this happened in practice, and existing debates are stalling because of a lack of detailed comparative research. This project offers the opportunity to move these debates forward by analysing alternative documentary evidence (from judicial and notarial archives), which allows considerable methodological advances through the detailed comparative analysis of the protagonists’ trading strategies. It is a central contention of this project that legal and financial differences in the treatment of crews were one of the crucial factors in the success of northern European economies in their commercial penetration of the Mediterranean, a necessary step in their struggle for global hegemony. A comparative approach to the study of wage controversies in four European economies which had a strong maritime sector – Italy, England, France, Netherlands – will bring new light on the everyday legal cases with which international commercial law was being formulated on the ground, and with an interesting new perspective of the effect of economic activities on the development of legal institutions. These topics have also a strong connection to contemporary issues such as how a mature economy (the early modern Italian) reacted to a structural crisis and the aggressive competition of rising economic and political powers (England, United Provinces).;848787;848787;ERC-2011-StG_20101124;/ERC-SG;THE UNIVERSITY OF EXETER;UK;;;"/SCI;/SOC";1;0;0;1;0;0 97340;264115;STREAM;ONG;FP7-REGPOT;REGPOT;FP7;Strengthening the Romanian research capacity in Multifunctional Polymeric Materials;2011-01-03;2014-07-02;;"Within the STREAM project, PPIMC aims at further strengthening its research capacity in the targeted scientific sectors by means of mobility and knowledge exchanges with excellent research EU institutions, participation and organisation of scientific events, hiring of experienced researchers, up-grading of its laboratories and networking with both industry and other research organisations, but most of all through a complete reshaping of its internal organisation. PPIMC ambitions are to adopt a totally integrated interdisciplinary approach around four research areas, defined by the Institute as priorities, in order to converge towards excellence on a crucial topic: “high added value multifunctional polymeric materials: concepts, mechanisms, properties, application”. The project will strengthen the research excellence of the institute and will therefore increase the attractiveness of the scientific career for young researchers in Romania. Further, the project will reinforce the capacity of business and governmental exploitation of research results and cooperation with industry and will set up a bridge between the Romanian chemical network and the European Research Area. In order to meet the main goal to improve the research potential at PPIMC, STREAM plans to reinforce and strengthen the established collaborative links with leading European institutions undertaking research and practice in Polymer Science. A complex schedule of exchange visits at different scientific level will allow the transfer of knowledge in the area of planning according to the social needs, management and supervision of strategic research activities in the concerned field. Within the STREAM proposal PPIMC will collaborate actively with 13 research centres from France, Germany, Poland, Slovenia, Spain and Switzerland.";3138971,2;2799999,32;FP7-REGPOT-2010-1;/CSA-SA;INSTITUTUL DE CHIMIE MACROMOLECULARA PETRU PONI;RO;;;"/SCI;/ITT";1;0;0;1;0;0 96077;260534;PISILENCE;ONG;FP7-IDEAS-ERC;ERC-SG-LS1;FP7;Small RNA-guided complex machinery for epigenetic silencing;2011-01-01;2016-05-31;;"Transposons are parasitic DNA elements that when activated can insert into new genomic locations, leading to genome instability. Animal germlines express a special class of small RNAs called piwi-interacting RNAs (piRNAs) which are implicated in transposon silencing. In mammals, they are believed to promote DNA methylation of transposon-rich genomic regions. Mechanisms of piRNA biogenesis and function are only beginning to be understood. Sequence analysis of piRNAs from a variety of organisms has given rise to working models for piRNA biogenesis and how piRNAs might act as guides for nuclear silencing complexes. However, key components of the pathway, especially those for biogenesis and function, remain to be discovered. Our aim is to identify and characterize new components using a combination of biochemistry, mouse genetics and small RNA bioinformatics. The regulatory potential of posttranslational modification of piwi proteins and their recognition by tudor proteins will be examined. Mouse mutants will be used to study the in vivo role of catalytic activity of piwi proteins in piRNA biogenesis and identify putative targets by transcriptomics approaches. Integrated biochemical and deep-sequencing methods will be applied to understand how small RNAs might guide nulcear silencing machinery to target locations. Finally, in a field that is dependent on model organisms, we propose to develop a cell culture system to study the piRNA pathway and carry out a high-throughput functional RNAi screen for component discovery. This proposal aims to use interdisciplinary approaches in uncovering the biochemical framework in which germline small RNAs function to protect eukaryotic genomes.";902849;902849;ERC-2010-StG_20091118;/ERC-SG;EUROPEAN MOLECULAR BIOLOGY LABORATORY;DE;;;"/BIO;/LIF";1;0;0;1;0;0 97283;251250;SNAKES AT SEA;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IOF;FP7;Evolutionary transition to marine life: novel insight from sea snakes;;;;Evolutionary transitions from terrestrial to marine life entail massive modifications. Marine mammals and birds exhibit major adaptations of their morphology and physiology to increase the depths to which they can dive, and the time during which they can remain underwater. Marine reptiles have attracted far less attention in this respect, but we expect ectotherms to diverge dramatically from endotherms in several dive parameters, especially because ectothermy reduces oxygen demand. The failure to observe an exaggeration of respiratory capacities in marine reptiles, suggests that the primary adaptations for diving will be morphological and behavioural rather than physiological. Sea snakes provide an excellent model for studying the evolutionary transition between the terrestrial and marine environments, because sea snake species encompass a wide continuum in terms of the degree of their dependence on the ancestral terrestrial environment. Because significant constraints apply on a snake’s morphology and ability to efficiently move through the water, the aim of this project is to investigate diving behaviour and associated adaptations within a group of ectothermic air-breathing vertebrates (snakes) that has evolved to exploit aquatic environments. We will use two complementary approaches (experimental biomechanics and free-ranging bio-logging) to comprehensively study sea snake underwater movements and diving behaviour. This project therefore sets out to use an integrative and interdisciplinary approach to fill a major gap in our understanding of diving behaviour and associated morpho-functional adaptations, by focusing on a group of reptiles that has successfully conquered the marine environment: the sea snakes.;253421,6;253421,6;FP7-PEOPLE-2009-IOF;/MC-IOF;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FR;;;"/LIF;/EDU";1;0;0;1;0;0 96094;262898;FAMINE;ONG;FP7-IDEAS-ERC;ERC-SG-SH5;FP7;Relocated Remembrance: the Great Famine in Irish (Diaspora) Fiction, 1847-1921;2010-10-01;2015-09-30;;"The Great Hunger (1845-49) radically transformed Ireland: it led to the wide-scale eviction of farmers, killed one million of the rural population, and caused massive emigration to other parts of the British Empire and the United States. Moreover, the Great Famine encouraged anti-English, nationalist sentiments and its trauma is pivotal to the development of an Irish postcolonial consciousness between 1847-1921. There is a vast unexplored transatlantic corpus of prose fiction, written between the aftermath of the Famine and the Anglo-Irish Treaty of 1921, which remembers the years of starvation and diaspora. My project is the first to inventorise and bring together this under-researched body of literature, written in Ireland and by Irish immigrants in England, Canada and the United States. This fiction requires intensive examination for significant reasons, offering alternative perspectives on how the Famine was culturally experienced than previous studies have displayed, and representing subaltern voices and recollections. Moreover, the texts are written in the homeland as well as in diaspora, by migrated Irish or their descendants. An examination of the corpus will therefore move beyond the largely nation-oriented frontiers of cultural memory studies towards innovative, transnational approaches. The project specifically investigates how remembrance is mediated through time, from one generation to another, and space, in diaspora. It aims to evolve a novel theoretical model about the interaction between temporal and spatial relocation in literary remembrance. This pioneering model will generate groundbreaking insights into the interaction between memory and ethnic identity in comparative contexts of cultural dislocation, a colonised homeland and migrant communities; and in processes of cultural relocation: de-colonisation and ethnic integration. At the same time, the project will analyse genre aspects which play a dynamic role in processes of cultural remembrance, contributing a new perspective to the interdisciplinary debate on media of recollection in cultural memory studies.";741000;741000;ERC-2010-StG_20091209;/ERC-SG;STICHTING KATHOLIEKE UNIVERSITEIT;NL;;;/SOC;1;0;0;1;0;0 102791;298761;ALMOND;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IEF;FP7;Algorithms and Tools for Mining Biological Sequence Data;2012-07-15;2014-07-14;;"'The goal of this proposal is to set up an interdisciplinary research training in the area of bioinformatics algorithms, that should lead to establishing a new level of expertise in certain techniques, methods and algorithms for handling the ever-increasing volume of biological sequence data (DNA, RNA, proteins). Bioinformatics is one of the flourishing research fields at the Computer Science Department of Ben-Gurion University in Israel, including four four faculty members and numerous growing collaborations with biological partners. In general, Ben-Gurion University is one of the most rapidly developing in Israel and provides a vibrant research atmosphere. Besides extending the range of competences to new research areas and increasing the actual expertise , this training will continue a recently started fruitful and promising collaboration between the applicant and the host institution, and should result in a series of high-level publications and new software tools available to the bioinformatics community. Moreover, the training is expected to lead to further collaborative projects involving the partners of the present proposal.'";250106;250106;FP7-PEOPLE-2011-IEF;/MC-IEF;BEN-GURION UNIVERSITY OF THE NEGEV;IL;;;/SCI;1;0;0;1;0;0 100672;284338;AR.C.H.I.VES;ONG;FP7-IDEAS-ERC;ERC-SG-SH6;FP7;A comparative history of archives in late medieval and early modern Italy;2012-02-01;2016-07-31;;"Most historians work in archives, but generally have not made archives into their primary object of research. While we tend to be preoccupied by documentary loss, what is striking is the sheer amount of paperwork preserved over the centuries. We need to study the reasons for this preservation. This project wishes to study the history of the archives and of the chanceries that oversaw their production storage and organization in late medieval and early modern Italy: essentially from the creation of the first chanceries in city-states in the late twelfth century to the opening of the Archivi di Stato that, after the ancient states’ dissolution, preserved documents as tools for scholarship rather than administration. Because of its fragmented political history, concentrating on Italy means having access to the archives of a wide variety of regimes; in turn, as institutions pursuing similar functions, archives lend themselves to comparison and therefore such research may help us overcome the traditional disconnectedness in the study of Italy’s past. The project proposes to break significantly new ground, first, by adopting a comparative approach through the in-depth analysis of seven case studies and, second, by contextualising the study of archives away from institutional history in a wider social and cultural context, by focusing on six themes researched in six successive phases: 1) the political role of archives, and the efforts devoted by governments to their development; 2) their organization, subdivisions, referencing systems; 3) the material culture of documents and physical repositories as well as spatial locations; 4) the social characteristiscs of the staff; 5) the archives’ place in society, including their access and misuse; 6) their use by historians. As implied in the choice of these themes, the project is deliberately interdisciplinary, and aims at the mutually beneficial exchange between archivists, social, political cultural and art historians.";1107070;1107070;ERC-2011-StG_20101124;/ERC-SG;BIRKBECK COLLEGE - UNIVERSITY OF LONDON;UK;;;"/SCI;/SOC";1;0;0;1;0;0 94237;249976;NEXTGENMOLECOL;ONG;FP7-IDEAS-ERC;ERC-AG-LS8;FP7;Next Generation Molecular Ecology;2010-04-01;2015-09-30;;There is an immediate need to increase our understanding of the genetic basis for fitness differences in natural populations (Ellegren and Sheldon Nature 452:169-175, 2008). Fortunately, technological developments within genome research, notably the recent ability to retrieve massive amounts of DNA sequence data based on next generation sequencing , will make possible completely novel investigations of the link between genotypes and phenotypes in non-model organisms. With our background as major players in molecular ecology and evolutionary genomics of non-models for the last 15-20 years, we are excellently placed to take on a leading role in this process, developing a Next Generation Molecular Ecology . This research program will combine studies of candidate genes with large-scale gene expression analysis, several mapping approaches and comparative genomics to study the genetic basis of trait evolution in wild bird populations. First, we will search for and analyse loci involved with reproductive isolation and adaptive population divergence in a well-known system for speciation research the pied flycatcher and the collared flycatcher. A milestone of this program will be genome sequencing of the two flycatcher species. Second, we will track the genetic basis of behaviour using a unique breeding population of zebra finches and benefitting from the recently obtained genome sequence of this species. Third, we will identify the targets for adaptive evolution during avian evolution using comparative genomics. Overall, the program will be able to reveal the molecular genetic architecture behind phenotypic variation. The potential for scientific break-through in this interdisciplinary program should be significant.;2500000;2500000;ERC-2009-AdG;/ERC-AG;UPPSALA UNIVERSITET;SE;;;"/BIO;/LIF";1;0;0;1;0;0 94558;245257;PRO-EEL;ONG;FP7-KBBE;KBBE-2009-1-2-13;FP7;Reproduction of European Eel: Towards a Self-sustained Aquaculture;2010-04-01;2014-07-31;http://www.pro-eel.eu/;The recent decline of European eel (Anguilla anguilla) and no signs of recovery has brought attention to the biologically unsustainable exploitation of the stock. In September 2007, the EU has adopted the Council Regulation 1100/2007 establishing measures for the recovery of the European eel stock. However, eel are still fished intensively for human consumption while aquaculture and restocking rely exclusively on the supply of glass eels caught each year. A controlled production of eel larvae is ever more urgent. The objective of PRO-EEL is to develop standardised protocols for production of high quality gametes, viable eggs and feeding larvae. The approach is to expand knowledge about the intricate hormonal control and physiology of eels which complicates artificial reproduction. This knowledge will be applied in the development of suitable methods to induce maturation considering different rearing conditions. Knowledge about the gametogenesis and maturation pattern will be developed in small scale tests and applied to establish standardised fertilisation procedures. New knowledge about functional anatomy of embryos and yolksac larvae will be applied to develop suitable feed. Protocols for larval production will be tested in full scale experimental facilities managed in collaboration with a qualified SME. The integrated protocols and technology development will be evaluated relative to the output of healthy embryos and yolksac larvae. Larval feeds will be developed towards pioneering first-feeding in European eel larvae, which will be a major breakthrough and promising step towards a self-sustained aquaculture. The strength of the project is its interdisciplinary approach and the unique expertise of the consortium. PRO-EEL brings together leading institutes in eel reproduction complemented by excellence in disciplines filling gaps in knowledge and technology. A tight collaboration with the aquaculture industry promotes the applicability of developed technology.;5087330,6;2999307;FP7-KBBE-2009-3;/CP-FP;DANMARKS TEKNISKE UNIVERSITET;DK;"HAVFORSKNINGSINSTITUTTET;Billund Aquakulturservice ApS;UNIVERSITEIT LEIDEN;UNIVERSITEIT GENT;BIOMAR A/S;NOFIMA AS;KOBENHAVNS UNIVERSITET;WAGENINGEN UNIVERSITY;UNIVERSITAT POLITECNICA DE VALENCIA;Institut National des Sciences et Technologies de la Mer;INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU;STICHTING WAGENINGEN RESEARCH";"NO;DK;NL;BE;ES;TN;FR";/SEA;1;0;0;1;0;0 96593;263293;JSMA;ONG;FP7-IDEAS-ERC;ERC-SG-SH6;FP7;Jews and Slavs in the Middle Ages: Interaction and Cross-Fertilization;2010-11-01;2016-10-31;;"The central purpose of this project is to bring down interdisciplinary barriers by showing how the Slavic and the Jewish heritage can each be approached as a unique repository of the unknown texts, traditions, and sensibilities of the other. By focusing on previously unexplored or under-explored medieval texts, I aim to reconstruct the Jewish and Slavic legacies, some of whose materials have been considered lost, while others were misinterpreted or neglected. This research project will resort to historical and philological techniques hitherto considered mutually incompatible in this field. The study intends to use methods of cultural archaeology to explore medieval Judeo-Slavic transparency. By cultural transparency we understand the mutual permeability of different cultures, which facilitates the exchange of ideas and genres of creativity between them. Cultural archeology involves methods of multi-disciplinary research based on the assumption that Eastern Europe constituted a melting pot characterized by an intensive cross-fertilization of cultural legacies. Cultural archaeology studies different historical, religious, and literary texts by looking at them as a palimpsest in which earlier texts and types of discourse come to the fore as shaped by their contemporary socio-cultural settings. The proposed theme has far-reaching methodological implications beyond the Judeo-Slavic cultural realm. This project will build a model of cross-cultural interaction to achieve a better understanding of the situations in which different faith-based ethnic cultures cohabit.";1043999,6;1043999,6;ERC-2010-StG_20091209;/ERC-SG;THE HEBREW UNIVERSITY OF JERUSALEM;IL;;;"/SCI;/SOC";1;0;0;1;0;0 111481;603839;ASTARTE;ONG;FP7-ENVIRONMENT;ENV.2013.6.4-3;FP7;Assessment, STrategy And Risk Reduction for Tsunamis in Europe;2013-11-01;2017-04-30;;"The NEAM (North East Atlantic, Mediterranean and Adjacent Seas) region of IOC/UNESCO is known to be exposed to tsunamis and, like other regions of the world, faces increasing levels of risk due to i) continuous development of coastal areas with critical infrastructure, and ii) year-round presence of millions of tourists. In recent years, European researchers have greatly advanced knowledge of tsunami hazards and implementation of operational infrastructure, such as creation of a regional system of candidate tsunami-watch providers (CTWP) and national tsunami warning centers (NTWC). However, significant gaps remain and more effort is needed. ASTARTE (Assessment STrategy And Risk for Tsunami in Europe) aims to develop a comprehensive strategy to mitigate tsunami impact in this region. To achieve this goal, an interdisciplinary consortium has been assembled. It includes all CTWPs of NEAM and expert institutions across Europe and worldwide. ASTARTE will improve i) basic knowledge of tsunami generation and recurrence going beyond simple catalogues, with novel empirical data and new statistical analyses for assessing long-term recurrence and hazards of large events in sensitive areas of NEAM, ii) numerical techniques for tsunami simulation, with focus on real-time codes and novel statistical emulation approaches, and iii) methods for assessment of hazard, vulnerability, and risk. ASTARTE will also provide i) guidelines for tsunami Eurocodes,ii) better tools for forecast and warning for CTWPs and NTWCs, and iii) guidelines for decision makers to increase sustainability and resilience of coastal communities. In summary, ASTARTE will develop basic scientific and technical elements allowing for a significant enhancement of the Tsunami Warning System in the NEAM region in terms of monitoring, early warning and forecast, governance and resilience. Overall, this will lead to the goal of the European/NEAM Horizon 2020 strategy: to foster tsunami resilient communities.";7884882,47;5999677,8;FP7-ENV-2013-two-stage;/CP;INSTITUTO PORTUGUES DO MAR E DA ATMOSFERA IP;PT;"NATIONAL UNIVERSITY CORPORATION THEUNIVERSITY OF TOKYO;SPECIAL RESEARCH BUREAU FOR AUTOMATION OF MARINE RESEARCHES FAR EAST BRANCH RUSSIAN ACADEMY OF SCIENCES;UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN;CENTRE NATIONAL POUR LA RECHERCHE SCIENTIFIQUE ET TECHNIQUE;INSTITUTUL NATIONAL DE CERCETARE-DEZVOLTARE PENTRU FIZICA PAMANTULUI;UNIVERSITAET HAMBURG;COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES;HELMHOLTZ ZENTRUM POTSDAM DEUTSCHESGEOFORSCHUNGSZENTRUM GFZ;UNIVERSITAET BREMEN;UNIVERSITAT DE BARCELONA;STIFTELSEN NORGES GEOTEKNISKE INSTITUTT;DANMARKS TEKNISKE UNIVERSITET;ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA;UNIVERSIDAD DE CANTABRIA;PORT AND AIRPORT RESEARCH INSTITUTE;FUNDACAO DA FACULDADE DE CIENCIAS DA UNIVERSIDADE DE LISBOA FP;NATIONAL OBSERVATORY OF ATHENS;ISTITUTO NAZIONALE DI GEOFISICA E VULCANOLOGIA;BOGAZICI UNIVERSITESI;U.S. DEPARTMENT OF COMMERCE;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;POLYTECHNEIO KRITIS;UNIVERSITY OF SOUTHERN CALIFORNIA;MIDDLE EAST TECHNICAL UNIVERSITY;NATURAL ENVIRONMENT RESEARCH COUNCIL";"JP;RU;IE;MA;RO;DE;FR;ES;NO;DK;IT;PT;EL;TR;US;UK";/ENV;1;0;0;1;0;0 111334;618918;EMCOREP;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-CIG;FP7;Emergence of complex internal representations in humans;2013-09-01;2016-08-31;;Human learning is uniquely complex and powerful in terms of its efficiency, its level of abstraction and its range of skills compared to any other species. The proposed research will investigate the fundamental cognitive and computational foundations of human sensory learning in adults and infants in an integrated interdisciplinary manner. We will carry out behavioural studies, computational analyses and theoretical work, and the questions in each of these domains will be rigorously linked to the topics explored in the other domains. The behavioural studies will question the generally upheld notion that low-level statistical learning of regularities and high-level “rule learning” of explicit rules, hierarchical memories, and emerging abstract social notions must be two fundamentally different and separate types of processes in the brain. Together with the computational analyses, they will explore how short and long-term memory is involved in acquiring new knowledge based on sensory experience. In the domain of theory, we will explore the idea that instead of simple associative learning, what human cortical learning can be best captured by is an optimal probabilistic computation based on previously developed internal models of the world. Finally, the inclusion of both adult and child studies that are essentially identical in their structure, we will test the generality of our findings giving a uniquely synergetic flavor to our approach.;75000;75000;FP7-PEOPLE-2013-CIG;/MC-CIG;KOZEP-EUROPAI EGYETEM;HU;;;/LIF;1;0;0;1;0;0 111370;336528;IBDlipids;ONG;FP7-IDEAS-ERC;ERC-SG-LS6;FP7;Lipid antigens in intestinal inflammation and tumor development;2014-01-01;2018-12-31;;"Lipids play crucial roles in metabolism, immunity and cancer. In addition to their function as inflammatory mediators, lipids serve as antigens presented by CD1d and activate a subset of T cells called natural killer T (NKT) cells. While NKT cells are critical for human immunity, their uncontrolled activation contributes to inflammatory bowel disease (IBD), a group of diseases characterized by chronic intestinal inflammation and an increased risk of colorectal cancer (CRC). Specifically, NKT cells are the major source of pathogenic TH2 cytokines in the inflammatory bowel disease ulcerative colitis (UC), are sufficient to cause intestinal inflammation in mice, and are required for colitis and colitis-associated cancer in a mouse model of UC. These observations suggest that targeting of lipid antigen presentation may be of therapeutic value in IBD, where current therapies are of limited efficacy and aim at control rather than cure of disease. Here, I propose to identify the lipid antigens responsible for NKT cell-mediated intestinal inflammation and colitis-associated cancer in human IBD and mouse models of intestinal inflammation and to develop therapeutic strategies for interference with pathogenic lipid antigen presentation. Specifically, I propose to characterize the intestinal inflammation- and cancer-associated CD1d lipidome based on novel in vitro and in vivo models of cleavable CD1d and a recently established lipidomics approach. Furthermore, I propose to develop strategies for inhibition of the generation, loading and presentation of inflammation- and cancer-associated lipid antigens. These studies combine biochemical, immunological and high-throughput technologies in an interdisciplinary manner to provide the knowledge required for the generation of novel, efficacious therapies for the treatment of IBD. These studies will have major implications for IBD and other inflammatory, infectious, and neoplastic diseases at mucosal barriers.";1500000;1500000;ERC-2013-StG;/ERC-SG;TECHNISCHE UNIVERSITAET DRESDEN;DE;CHRISTIAN-ALBRECHTS-UNIVERSITAET ZU KIEL;DE;"/BIO;/LIF;/MED";1;0;0;1;0;0 111393;613004;ISSICEU;ONG;FP7-SSH;SSH.2013.4.1-1;FP7;Intra-and Inter-Societal Sources of Instability in the Caucasus and EU Opportunities to Respond;2014-01-01;2016-12-31;;"ISSICEU analyses sources of stability and instability in the Caucasus regarding political regimes, civic participation, economic interdependencies and neighbourhood influences. We evaluate the implications for military, political, economic and societal security. We deliver three relevant products for EU policy formulation: We analyse and map emerging conflicts of local, regional and international dimensions and highlight crucial actors and mechanisms. We elaborate on scenarios concerning potential future security developments. We give concise policy recommendations on opportunities for the EU to influence conflict solution and long-term stability in the Caucasus societies and the whole region. ISSICEU disseminates the findings as follows: policy briefs; expert workshops in relevant EU agencies and for stakeholders in EU countries and the Caucasus; a scenario-workshop at the final stage. ISSICEU explores intra-societal frictions and their regional impact in the political regimes focussing mainly on dynamics of communal governance; the interplay of religious and state actors and practices of civic participation. We analyse inter-societal sources of (in)stability regarding economic dependencies; political and societal relations between the Caucasus and neighbourhood states. ISSICEU makes comparative analyses across sub-regions and studies aspects of inter-societal relations. We consider the historical and contemporary ties among the societies. We study the Caucasus in its diversity and cohesiveness. Cases are Armenia, Azerbaijan, Georgia, Abkhazia, South Ossetia, Nagorno-Karabakh, Dagestan, Kabardino-Balkaria, Karachay-Cherkessia and Chechnya. In the neighbourhood we focus on Turkey and Iran. ISSICEU takes theory-informed, interdisciplinary and strongly inductive approaches, able to adequately identify phenomena as they manifest themselves in the region and to give innovative policy recommendations.";2165173,85;1573957,9;FP7-SSH-2013-2;/CP-FP-SICA;UNIVERSITAET ST. GALLEN;CH;"STIFTUNG WISSENSCHAFT UND POLITIK;TURKIYE EKONOMI POLITIKALARI ARASTIRMA VAKFI;STATE EDUCATIONAL INSTITUTION OF HIGHER PROFESSIONAL EDUCATION RUSSIANSTATE UNIVERSITY FOR THE HUMANITIES;KHAZAR UNIVERSITY;ANKARA POLITIKAR MERKEZI;GEOWEL RESEARCH;KABARDINO-BALKARIAN STATE UNIVERSITY NAMED AFTER KH M BERBEKOV;UNIVERSITE DE FRIBOURG";"DE;TR;RU;AZ;GE;CH";"/SOC;/POL";1;0;0;1;0;0 99018;274919;IAGT;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-IOF;FP7;Innovations in algorithmic game theory;2011-09-01;2014-09-30;;"The last decade has seen the emergence and prospering of a new interdisciplinary field of research often termed “Algorithmic Game Theory.” This field lies at the crossroads between computer science, game theory, and economics, a combination which is needed to address many of the challenges that the Internet poses. Not only is this field full of intellectual excitement internally, not only is it already intellectually influencing the three parent disciplines, but it also has significant applications on the Internet as can be seen from the large number of researchers in the field hired by Google, Yahoo, and Microsoft. The first decade of algorithmic game theory (AGT) has concentrated on several main theoretical themes along with their implications on various applications such as peer-to-peer networks, information markets, prediction markets, network security, and many others. The three theoretical themes that lie at the heart of AGT are: (i) algorithms for computing equilibria; (ii) algorithmic mechanism design; and (iii) inefficiency of equilibria. While there is no question that these three themes will continue to play an important role, and that the Internet will continue to be an important motivator, it is also clear that the field is rapidly evolving with new challenges, applications, and techniques constantly appearing on the scene. As part of the proposed project, I plan to concentrate on the following three main topics, all strongly rooted in the fields of game theory, mechanism design, algorithms, artificial intelligence, multi-agent systems, and communication networks: (i) truth and justice: the interplay between incentive compatibility and envy-freeness in mechanism design; (ii) complete versus incomplete information: quantifying the loss in social welfare arising due to partial information; and (iii) a prescriptive approach for playing games.";271445,64;271445,64;FP7-PEOPLE-2010-IOF;/MC-IOF;TEL AVIV UNIVERSITY;IL;THE HEBREW UNIVERSITY OF JERUSALEM;IL;"/EMP;/SOC;/COO";1;0;0;1;0;0 102055;282534;SDH-Net;ONG;FP7-HEALTH;HEALTH.2011.3.4-2;FP7;Building Sustainable Research capacity for Health and its Social Determinants in Low- and Middle-Income Countries;2011-10-01;2015-09-30;;"SDH-Net’s aim is to build, strengthen and link research capacities for health and its social determinants (SDH) in African and Latin American low- and middle income countries (LMIC) in close collaboration with European partners. The focus on SDH will allow for an in-depth and broad capacity-building approach, including managerial and technical excellence, ethical issues, and research strategies. Lessons learnt will be checked against best practices and success factors in other Latin American, African and global settings, leading to lessons learnt on how to build SDH-related research capacity with strong relevance to the respective context. A sound mapping exercise of (i) social determinants of health (SDH) and research activity in the field; (ii) national and global stakeholders in the research environment, and (iii) existing research capacities in the participating countries will be carried out building the basis for developing and piloting innovative research capacity building tools with a particular focus on research management, ethics and methodology relevant to comprehensively address social determinants of health. Finally, links between research and policy will be forged and lessons will be drawn to support the development of sustainable and attractive research structures and expertise. SDH-Net will be carried out by a strong consortium, based on clusters of existing networks of best in its kind public health institutions from Mexico, Colombia, Brazil and South Africa, Tanzania, and Kenya. The team is complemented by three distinguished European institutions: London School of Hygiene and Tropical Medicine; COHRED, and University of Geneva. SDH-Net is coordinated by GIZ with long term experience in health research and capacity building in LMIC, and IESE Business School, excellent in management capacity building. SDH-Net will have an important impact by developing a concept for research capacity building on individual, institutional and system level, contributing to research system strengthening and to the creation of research landscapes that enable and stimulate locally relevant, interdisciplinary research. It will lead to enhanced capacities for conducting and managing research on SDH and links between research, policy and practice will be forged by developing tools and mechanisms facilitating sustained collaboration. Furthermore, SDH-Net will lay foundations and provide tools for further research capacity building and research system strengthening in the future.";2354525,2;2000000;FP7-HEALTH-2011-single-stage;/CSA-CA;DEUTSCHE GESELLSCHAFT FUR INTERNATIONALE ZUSAMMENARBEIT (GIZ) GMBH;DE;"UNIVERSITE DE GENEVE;IFAKARA HEALTH INSTITUTE TRUST;UNIVERSITY OF THE WITWATERSRAND JOHANNESBURG;FUNDACAO OSWALDO CRUZ;UNIVERSIDAD NACIONAL DE COLOMBIA;LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE;UNIVERSIDAD DE NAVARRA;UNIVERSITY OF NAIROBI;INSTITUTO NACIONAL DE SALUD PUBLICA;COUNCIL ON HEALTH RESEARCH FOR DEVELOPMENT ASSOCIATION";"CH;TZ;ZA;BR;CO;UK;ES;KE;MX";/LIF;1;0;0;1;0;0 94753;249362;TRADE;ONG;FP7-IDEAS-ERC;ERC-AG-SH6;FP7;Europe's Asian Centuries: Trading Eurasia 1600-1830;2010-09-01;2014-08-31;;The project brings global perspectives and interdisciplinary methods to bear on histories of industrialization, consumer and material culture. It investigates the key connector that transformed the early modern world: the long-distance trade between Asia and Europe in material goods and culture. That trade stimulated Europe s consumer and industrial revolutions, re-orientating the Asian trading world to European priorities. The twenty-first century sees a new Asian ascendancy: Europe has lost those manufacturing catalysts of textiles, ceramics and metal goods back to Asia. This project seeks to understand Europe s new challenge of Asia by charting the history of that first global shift between the pre-modern and modern worlds. Europe s pursuit of quality goods in the 17th and 18th Centuries turned a pre-modern encounter with precious and exotic ornaments into a modern globally-organized trade in Asian export ware. But ironically the result was Europe s industrialization and China s and India s displacement as the world s manufacturer. The project compares Europe s trade with India in high quality textiles with its trade with China in porcelain using the records of Europe s East India companies and major museum collections of export-ware objects. The PI will research the English East India Company together with a PhD student, and lead three postdoctoral fellows in comparative case studies on other European companies, especially the Dutch, the French and Scandinavian companies. The research is groundbreaking in bringing the study of traded products, material cultures and consumption into economic and global history, and in making economic history relevant to wider cultural history. It has the vision of a history over a long time period and wide European and Asian comparisons and connections.;1544667;1544667;ERC-2009-AdG;/ERC-AG;THE UNIVERSITY OF WARWICK;UK;;;/SOC;1;0;0;1;0;0 110846;608553;IMAGE;ONG;FP7-ENERGY;ENERGY.2013.2.4.1;FP7;Integrated Methods for Advanced Geothermal Exploration;2013-11-01;2017-10-31;http://www.image-fp7.eu/;"'The IMAGE project will develop a reliable science based exploration and assessment method to 'IMAGE' geothermal reservoirs using an interdisciplinary approach based on three general pillars: 1 Understanding the processes and properties that control the spatial distribution of critical exploration parameters at European to local scales. The focus will be on prediction of temperatures, in-situ stresses, fracture permeability and hazards which can be deduced from field analogues, public datasets, predictive models and remote constraints. It provides rock property catalogues for 2 and 3. 2 Improving well-established exploration techniques for imaging and detection beyond the current state of the art and testing of novel geological, geophysical and geochemical methods to provide reliable information on critical subsurface exploration parameters. Methods include a) geophysical techniques such as ambient seismic noise correlation and magnetotellurics with improved noise filtering, b) fibre-optic down-hole logging tools to assess subsurface structure, temperature and physical rock properties, and c) the development of new tracers and geothermometers. 3 Demonstration of the added value of an integrated and multidisciplinary approach for site characterization and well-siting, based on conceptual advances, improved models/parameters and exploration techniques developed in 1 and 2. Further, it provides recommendations for a standardized European protocol for resource assessment and supporting models. The IMAGE consortium comprises the leading European geothermal research institutes and industry partners who will perform testing and validation of the new methods at existing geothermal sites owned by the industry partners, both in high temperature magmatic, including supercritical, and in basement/deep sedimentary systems. Application of the methods as part of exploration in newly developed fields will provide direct transfer from the research to the demonstration stage.'";13402774,21;10051044,75;FP7-ENERGY-2013-1;/CP;NEDERLANDSE ORGANISATIE VOOR TOEGEPAST NATUURWETENSCHAPPELIJK ONDERZOEK TNO;NL;"FONROCHE GEOTHERMIE SAS;VOLCANIC BASIN PETROLEUM RESEARCH AS;PETRATHERM ESPANA SL;BKW Energie AG;UNIVERSITE DE MONTPELLIER;HS ORKA HF;INSTITUTT FOR ENERGITEKNIKK;EDA RENOVÁVEIS, S.A.;HELMHOLTZ ZENTRUM POTSDAM DEUTSCHESGEOFORSCHUNGSZENTRUM GFZ;BUREAU DE RECHERCHES GEOLOGIQUES ET MINIERES;CONSIGLIO NAZIONALE DELLE RICERCHE;EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH;GEOMEDIA s.r.o.;TECHNISCHE UNIVERSITAT DARMSTADT;UNIVERSITE MONTPELLIER 2 SCIENCES ET TECHNIQUES;UNIVERSITEIT UTRECHT;UNIVERSITA DEGLI STUDI DI BARI ALDO MORO;ISLENSKAR ORKURANNSOKNIR;LANDSVIRKJUN SAMEIGNARFELAG;AXPO POWER AG";"FR;NO;ES;CH;IS;PT;DE;IT;CZ;NL";"/ESV;/EST";1;0;0;1;0;0 111261;330134;ARTEMIS;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IOF;FP7;Autoimmune Reaction or Tolerance - Endosymbiont Mitochondria and the Immune System;2014-08-01;2017-07-31;;Mitochondria, the powerhouses of our cells, are remnants of a eubacterial endosymbiont. Because mitochondria retain many hallmarks of their bacterial origin, they have recently been implicated in the etiology of systemic inflammatory response syndrome, a frequent cause of death in intensive care units. Remarkably, mitochondria are immunologically inert under normal homeostatic conditions, raising the fundamental question: how does the immune system distinguish mitochondria from resemblant bacterial pathogens? We hypothesize that mitochondria harbor distinct molecular signatures identifying them to the immune system. To address our hypothesis, we will investigate immune handling of intact mitochondria and mitochondria-derived danger-associated molecular patterns. The research objectives are to examine: 1) if isolated, intact mitochondria in vitro elicit pro-inflammatory signals or are recognized specifically as non-pathogenic by immune cells, 2) immune handling of intact and disrupted mitochondria in vivo by two-photon intravital microscopy, and 3) the role of innate signaling pathways in determining pro- or anti-inflammatory responses to mitochondrial challenges in vivo. The applicant has an international profile and an outstanding track record. He will combine a strong background in immunology with an interdisciplinary approach transcending the boundaries to organelle and symbiosis research. The project entails training in two-photon intravital microscopy at the outgoing host, the Immune Disease Institute, Harvard Medical School. This cutting-edge technique has emerged recently as a powerful tool for studying immune function in real-time in the intact organism. Hence, theoretical developments and technical innovations have converged to pave the way for the implementation of the proposed project, which will address fundamental mechanisms governing the balance between host immunity and autoinflammation, with a significant impact on human health and disease.;294456,3;294456,3;FP7-PEOPLE-2012-IOF;/MC-IOF;AARHUS UNIVERSITET;DK;;;/LIF;1;0;0;1;0;0 91156;230291;EGAIS;ONG;FP7-SIS;SiS-2008-1.1.2.1;FP7;The Ethical GovernAnce of emergIng technologieS – New Governance Perspectives for Integrating Ethics into Technical Development Projects and Applications;2009-05-01;2012-02-29;;"EGAIS will investigate the ethical governance in EU research projects with the goal of providing a framework for improved governance mechanisms that will address potential ethical issues arising from new and emerging technologies. The Ambient Intelligence projects will be used as a starting point of analysis, but the results will be tested to other emerging fields such as nanotechnologies, biodiversity and converging technologies. Usually projects with technical development do not sufficiently integrate the ethical issues that arise: the governance of ethics is missing and no guidelines have been provided at the EU and international level. These difficulties have been recognised at EU level, resulting in the attention paid to ethics and ICT in FP7 and partially in FP6. Adopting a bottom-up approach, EGAIS will investigate how ethical governance considerations could be embedded into the research and technology development culture of EU research so that they become a natural part of the evaluation and technical development process. The interdisciplinary project team will provide new governance guidelines addressing the integration of ethics into technical development projects that could be used in any field of technology development. Guidelines will emerge from the following steps: empirical analysis (of ethical governance measures within EU funded projects), classification of existing projects based on their ethical governance models and interpretation, application of theoretical outcomes to different technological domains to catalogue deficiencies in ethical governance mechanisms (portability of the problem), production of guidelines for concretely embedding ethics into projects in any EU technological development practices (portability of the solution). EGAIS will collect feedback from key stakeholders (EU policy makers, project leaders, academia, etc.) through a series of workshops. Dissemination activities will include the industry and civil society.";998218,57;837685;FP7-SCIENCE-IN-SOCIETY-2008-1;/CP;UNIVERSITA CATTOLICA DEL SACRO CUORE;IT;"INSTITUT INFORMACIJSKIH ZNANOSTI;INSTITUT CATHOLIQUE D'ARTS ET METIERS;MIDDLESEX UNIVERSITY HIGHER EDUCATION CORPORATION;UNIVERSITE DE NAMUR ASBL";"SI;FR;UK;BE";"/ETH;/SCI";1;0;0;1;0;0 111239;613354;CASCADE;ONG;FP7-SSH;SSH.2013.4.1-1;FP7;Exploring the Security-Democracy Nexus in the Caucasus;2014-02-01;2017-01-31;http://www.cascade-caucasus.eu/;"CASCADE will: - scrutinise Caucasian states and societies for the root causes of conflict and insecurity, conduct synergetic research on democracy and security in the Caucasus and investigate their interaction, - analyse the links between the region and its wider neighbourhood, - provide forward-looking analysis on regional security and democratisation processes, - and develop a set of proposals on how the EU could enhance its role in the region. The project will de-compartmentalise research on the Caucasus by exploring linkages between societal challenges, political developments and conflicts and investigating the interactions between the North and South Caucasus, as well as between the Caucasus and its wider neighbourhood. On the basis of a strong comparative and interdisciplinary approach, we will seek to provide a more accurate understanding of how democracy and security are perceived, understood, experienced and exploited as political and social resources by Caucasus actors and other actors involved in the region. Cooperation between researchers with backgrounds in different humanities will uncover the various facets of the relationship between democracy and security. Drawing upon extensive fieldwork in the North and South Caucasus, including in the conflict areas and de facto States, CASCADE will generate a wealth of empirical data as well as new and important insights into security and democracy in the Caucasus. The project’s outcomes will also be largely policy-driven and CASCADE’s impact will be considerable in terms of shaping EU policy toward the Caucasus. The project will act as a knowledge hub to spur debate and bring together academic and policy communities from Europe and the Caucasus.";3265587,33;2488450;FP7-SSH-2013-2;/CP-FP-SICA;FONDATION MAISON DES SCIENCES DE L'HOMME;FR;"MILLI VE BEYNELXALQ ARASDIRMALAR MERKEZI ASSOCIATION;GEORGIAN FOUNDATION FOR STRATEGIC AND INTERNATIONAL STUDIES - GFSIS;FUNDACION PARA LAS RELACIONES INTER NACIONALES Y EL DIALOGO EXTERIOR FRIDE;STIFTELSEN STOCKHOLMS INTERNATIONELLA FREDSFORSKNINGSINSTITUT;THE UNIVERSITY OF BIRMINGHAM;INTERNATIONAL CENTER FOR HUMAN DEVELOPMENT PUBLIC ORGANIZATION;Friedrich Schiller University Jena;RUSSIAN ACADEMY OF SCIENCES INSTITUTE OF GEOGRAPHY OF RUSSIAN ACADEMYOF SCIENCES;REGIONAL CENTRE FOR STRATEGIC STUDIES";"AZ;GE;ES;SE;UK;AM;DE;RU";"/SOC;/POL";1;0;0;1;0;0 111235;613202;IMPACT-EV;ONG;FP7-SSH;SSH.2013.8-1;FP7;Evaluating the impact and outcomes of European SSH research;2014-01-01;2017-12-31;;"The main objective of IMPACT-EV is to develop a permanent system of selection, monitoring, evaluation and comparison of the impact and outcomes from European SSH research, taking into account the latest quantitative and qualitative evaluation tools, identifying new ways of implementing them and exploring new standards and indicators that complement existing impact assessment processes. IMPACT-EV will contribute to developing a permanent system of selection, monitoring and evaluation of EU funded SSH research, therefore able to provide insights for the ex-ante, in-itinere and ex-post evaluation concerning assessment of the scientific, policy and social impact of SSH research project outcomes. Scientific impact involves quality of publications, training of young researchers, forms of interdisciplinarity and the constitution of European scientific excellence networks; in policy impact we will focus on EU directives or recommendations, national, regional and local policies; by social impact we understand results of the policies and citizens’ actions based on research evidence in relation to the five EU 2020 targets (i.e. increased employment among 20-64 years old, increased investment in R&D/I, increase in energy efficiency and renewables, reducing dropout rates and increasing third level education, and reducing poverty and social exclusion). In addition, the impacts of SSH research projects on the development of the European Research Area in SSH (e.g. ERA-Nets and of art. 185 initiatives in the domain of SSH, the mobility of researchers and the circulation of concepts across national and disciplinary borders) will be also analysed.";2989054,8;2271709;FP7-SSH-2013-2;/CP-FP;UNIVERSITAT DE BARCELONA;ES;"THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN;KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW;POPULATION AND SOCIAL POLICY CONSULTANTS GCV;MAGYAR TUDOMANYOS AKADEMIA KONYVTARA;CARDIFF METROPOLITAN UNIVERSITY;UNIVERSITA DELLA SVIZZERA ITALIANA;CONSIGLIO NAZIONALE DELLE RICERCHE;BRUNEL UNIVERSITY LONDON";"IE;NL;BE;HU;UK;CH;IT";"/SOC;/POL";1;0;0;1;0;0 105205;307087;SPARCS;ONG;FP7-IDEAS-ERC;ERC-SG-PE7;FP7;Statistical Physics Approach to Reconstruction in Compressed Sensing;2012-10-01;2018-09-30;;"Compressed sensing is triggering a major evolution in signal acquisition: it indicates that most data, signals and images, that are usually compressible and have redundancy, can be reconstructed from much fewer measurements than what was usually considered necessary, resulting in a drastic gain of time, cost, and measurement precision. In order to make this groundbreaking improvement possible, compressed sensing deals with how measurements should be performed, and how, in a second step, to use computational power in order to reconstruct the original signal. Compressed sensing can be used for many applications (speeding up magnetic resonance imaging without the loss of resolution, performing X-ray scans with less radiation exposure, sensing and compressing data simultaneously, measurements in acoustic holography, in system biology, faster confocal microscopy, etc ...). Currently used measurement protocols and reconstruction techniques, however, are still limited to acquisition rates considerably higher than what is theoretically necessary. The aim of this project is to develop a new interdisciplinary approach to compressed sensing, based on a statistical physics inspired methodology, whose preliminary application by the PI already yield spectacular results. I propose to use both a new algorithm for the reconstruction algorithm, with a mean-field inspired “Belief Propagation” method, and a new class of compressed sensing measurement schemes, motivated by a statistical physics study of the problem and by the theory of crystal nucleation in first order transitions. For reasons detailed below, this statistical physics approach is extremely promising theoretical framework to tackle compressed sensing and I believe it can eventually lead to optimal performance. I expect that the progress we will make in this direction will be instrumental also for other inference and inverse problems at the crossroad between physics and computer science.";1077960;1077960;ERC-2012-StG_20111012;/ERC-SG;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FR;;;"/PSE;/AER;/SPA";1;0;0;1;0;0 185454;602768;ACTION;ONG;FP7-HEALTH;HEALTH.2013.2.2.1-3;FP7;Aggression in Children: Unraveling gene-environment interplay to inform Treatment and InterventiON strateg;2014-06-01;2019-05-31;;"Aggression inflicts a huge personal, psychological and financial burden on affected individuals, their relatives, and society at large. Despite large scientific, preventive, and treatment investments, no decrease in aggressive behavior is seen. This calls for a shift to new approaches. By capitalising on comprehensive longitudinal cohorts, recent advances in genetic, biological, epidemiological, and clinical fields, and combining such interdisciplinary expertise the ACTION consortium will dissect the etiology and pathogenesis of aggression. Based on new insights, ACTION will inform the development of novel diagnostic tools and causative targets and guide the development of treatment and prevention strategies. ACTION is built on interrelated work packages with a focus on a) clinical epidemiology and current classification and treatment problems; b) genetic epidemiology, including Genome Wide Association studies and epigenetics; c) gene-environment correlation and interaction; d) biomarkers and metabolomics. ACTION will deliver an overarching framework that combines a thorough understanding of pathways leading to aggression with a map of current gaps, best practices on clinical, ethical, legal, and social issues. Based on this framework, ACTION will develop novel biomarkers suitable for large-scale applications in children and combine biomarker data with new insights into the effects of gender, age, and comorbidity. ACTION will provide guidance in optimising current intervention programs and deliver new biological targets to pave the way for novel therapeutic interventions. ACTION will provide a decision tree to guide personalised intervention programmes and will have direct and sustained impact on reducing paediatric aggression. Its overarching aim is to reduce aggression by developing approaches that take individual differences in genetic and environmental susceptibility into account, thereby leading to better understanding of personalised intervention programs.";8736901,84;5999079,4;FP7-HEALTH-2013-INNOVATION-1;/CP-FP;STICHTING VU;NL;"ACADEMISCH ZIEKENHUIS LEIDEN;GOOD BIOMARKER SCIENCES BV;UNIVERSITEIT LEIDEN;HELSINGIN YLIOPISTO;DIAGENODE;University of Notre Dame du Lac;UNIVERSITA DEGLI STUDI DI CAGLIARI;QUEENSLAND INSTITUTE OF MEDICAL RESEARCH;KAROLINSKA INSTITUTET;ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM;KING'S COLLEGE LONDON";"NL;FI;BE;US;IT;AU;SE;UK";/LIF;1;0;0;1;0;0 111268;612589;CHETCH;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IRSES;FP7;China and Europe taking care of healthcare solutions;2014-01-01;2017-12-31;;"The research project intends to contribute actively to the cooperation between Europe and China, investigating opportunities for mutual integration in the healthcare sector. Cooperation and potential synergies will be examined from a comprehensive perspective, including policies at national and local level, the legal environment, medical practices, healthcare industries and related businesses. An interdisciplinary approach is followed. Researchers in the social science and humanities areas will compare the European and Chinese healthcare systems at different levels, including value systems and ethical issues. The economic expert will analyse the integration reached so far, in the healthcare industries (i.e. technologies, pharmaceutical products, etc.) on the basis of foreign direct investments, trade and micro economic data. The typical cost-benefit tools will be used to evaluate the economic impact of integrating Western Medicine (WM) and Traditional Chinese Medicine (TCM) practices, supporting the medical team of experts. The legal instruments will help define obstacles and plausible solutions that can be generated by the regulatory environment, as well as appropriate solutions to enhance collaboration both at institutional, medical practices and business levels. The team of experts in the medical field will investigate best practices of traditional medical systems using a modern science framework. The team will develop a process of recognition and scientific validation of TCM versus Complementary Alternative Medicine, at different levels. CHETCH is based on the idea that a Europe-China partnership could be a win-win strategy. Europe and China have complementarities that could help each other face their specific needs in the long run.";688800;688800;FP7-PEOPLE-2013-IRSES;/MC-IRSES;UNIVERSITA POLITECNICA DELLE MARCHE;IT;"ASSOCIAZIONE MEDICI AGOPUNTORI BOLOGNESI;UNIVERSITA DEGLI STUDI DI MACERATA;VRIJE UNIVERSITEIT BRUSSEL;FUNDACIO EUROPEA DE MEDICINA TRADICIONAL XINESA INSTITUT CATALUNYA-YUNNAN ESCOLA SUPERIOR DE MEDICINA TRADICIONAL XINESA;UNIVERSITA DEGLI STUDI DI FERRARA";"IT;BE;ES";/LIF;1;0;0;1;0;0 100130;282586;ROAMER;ONG;FP7-HEALTH;HEALTH.2011.3.3-4;FP7;A Roadmap for Mental Health Research in Europe;2011-10-01;2015-03-31;http://www.roamer-mh.org/;"On the regional level, Europe has one of the highest levels of resources for mental health care. Despite this, the high burden and impact of mental disorders in Europe is expected to rise. “ROAdmap for Mental health Research” (ROAMER) is designed to develop a comprehensive, consensus-based roadmap to promote and integrate mental health and well-being research in Europe. Research advances and innovations are to be devoted to decreasing the burden of mental disorders and increasing the mental health and well-being of Europeans. ROAMER will combine a neutral, fact-based methodology with extensive stakeholder involvement in consultation and dissemination. During the kick-off phase, the methodology (including comprehensive EU-wide indicators to assess the current state of the art, gaps and advances) and the desired situation (scoping and objectives) will be finalised. Secondly, the current state of the art will be examined, using these tools. In the third phase, the desired situation will be compared with the current situation to identify gaps and advances. Phase four prioritises these gaps and advances, as well as solutions. In the fifth phase, this information is translated into roadmaps covering infrastructures, capacity building and funding strategies for scientific areas relevant to mental health and well-being: biomedical, psychological, social, economic and public health. Geographical, interdisciplinary, developmental, gender and age perspectives will be taken into account. To achieve consensus among a broad group of scientists, service users, carers, government and funding institutions and other stakeholders, ROAMER uses web-based survey’s, scientific workshops, scientific advisory board meetings, stakeholder meetings, consensus meetings, and policy meetings. The consortium consists of leading experts in the field, and is well balanced in terms of geographical distribution and complementary expertises across all relevant aspects of mental health research.";2265950,41;1999138;FP7-HEALTH-2011-single-stage;/CSA-CA;CENTRO DE INVESTIGACION BIOMEDICA EN RED;ES;"CFc srl;THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE;THE UNIVERSITY OF MANCHESTER;LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE;Fondation FondaMental;UNIVERSITEIT MAASTRICHT;NORDISKA HÖGSKOLAN FÖR FOLKHÄLSOVETENSKAP;SEMMELWEIS EGYETEM;UNIVERSITA DEGLI STUDI DELLA CAMPANIA LUIGI VANVITELLI;ZENTRALINSTITUT FUER SEELISCHE GESUNDHEIT;KING'S COLLEGE LONDON;TECHNISCHE UNIVERSITAET DRESDEN";"IT;UK;FR;NL;SE;HU;DE";/LIF;1;0;0;1;0;0 111333;618692;AoD;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-CIG;FP7;AESTHETICS OF DECOLONISATION: ARTISTS, MODERNISMS AND NATION-STATES IN INDIA, WEST AND EAST PAKISTAN, 1947-71;2013-10-01;2017-09-30;;"AESTHETICS OF DECOLONISATION will study artists, ideologies, and cultural imaginaries across the split political contexts of India and Pakistan. It will cover the climactic decades of decolonisation, from the exit of British rule and the partition of India and Pakistan in 1947 to a second partition and the War of Liberation in 1971 that splintered East Pakistan from West, forming the current Bangladesh. Retreating from this theatre of border conflict, war, displacement, and genocide, this project will instead foreground cultural governance, and artistic dialogues and negotiations, from the early post-colonial decades. It will focus on the new categories of ‘artist-bureaucrats’ and ‘artist-pedagogues’ from India, East and West Pakistan, and follow their trajectories through postwar global collaborative forums like the UNESCO, the Commonwealth, and post-Bandung Afro-Asian solidarities, and the Rockefeller and Ford Foundations, as well as the art worlds of the Eastern Bloc. It will ask new questions, disclose new archival material, and forge new analytical tools to connect ‘national’ and ‘vernacular’ artistic imaginaries to trans-national debates on universal and partisan art habitually steeped in Cold War rhetoric. Developing interdisciplinary tools to read, merge, and juxtapose political and cultural modernities during decolonisation, AESTHETICS OF DECOLONISATION will raise the following questions: How can we conceptualise post-colonial art from South Asia as a ‘region’ beyond tense national frontiers? How can the national-vernacular-global triad be activated as a conceptual frame to map alternative geographies of twentieth-century artistic modernisms? How can new ‘non-Western’ art histories historicise the contemporary in Asian Cultural Studies? And finally, how can we develop cross-national analytical models that will connect the distinctly national narratives of post-colonial art from the Global South?";100000;100000;FP7-PEOPLE-2013-CIG;/MC-CIG;UNIVERSITEIT LEIDEN;NL;;;/LIF;1;0;0;1;0;0 111329;608153;PHD4ENERGY;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-ITN;FP7;"""Nanoscale Materials for Energy: Fundamentals, Applications and Safety""";2014-02-01;2018-01-31;;'One of Humanity’s most urgent and greatest scientific and technological challenges is the need for more efficient methods to access renewable energy sources and ways to reduce energy consumption. Nanotechnology opens up fundamentally novel routes to address these challenges. With focus on the unique opportunities offered by III-V nanowires and molecular engineering, PhD4Energy will develop (i) highly-efficient, cost-effective, and flexible NW solar cells, (ii) cost effective, phosphor-free LEDs for RGB and lighting with optimised color rendering index and very low energy consumption , (iii) practical methods to enhance the thermoelectric performance of nanomaterials, and we will (iv) pioneer the use of Nature’s choice of material (proteins) for direct chemical-to-mechanical energy conversion in artificial molecular machines. Furthermore, PhD4Energy will concurrently evaluate the safety and sustainability of our novel nanomaterials and device fabrication. In order to train early-stage researchers in the skills and methods necessary for succeeding with the proposed research and its industrial applications, PhD4Energy builds an innovative doctoral program (IDP) that with 9 partners from the private sector, combines high-level, interdisciplinary research with an extensive secondment program. The IDP will be designed to last beyond the tenure of PhD4Energy, and will serve a best-practice model for PhD education that effectively bridges the gap between academic research and in-terest of commercialization. A key feature of the training program is the direct input of industry leaders on the students’ course menu, greatly enhancing employability. The training program will be embedded into the major materials science research hub at Lund in Sweden, comprising of the Nanometer Structure Consortium at Lund University, the synchrotron Maxlab, the future ESS spallation source, and a cluster of spin-off companies that actively pursue commercialisation of nm based research.';3184248,32;3184248,32;FP7-PEOPLE-2013-ITN;/MC-ITN;LUNDS UNIVERSITET;SE;;;/LIF;1;0;0;1;0;0 106578;316738;RADOX;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-ITN;FP7;RADical reduction of OXidative stress in cardiovascular diseases;2013-01-01;2016-12-31;http://radox.org/;Cardiovascular disease (CVD) constitutes a major and increasing health burden in developed countries. The prediction is that the prevalence of these conditions will increase by ~60% over the next 20 years. Therefore, the development of novel treatments for patients with CVD becomes more and more urgent. Oxidative stress is an important molecular contributor to the pathogenesis of CVD. However, oxidative stress-related therapeutic strategies are still missing. This ITN consortium links investigators highly active in the field of oxidative stress-signalling, and will strongly enhance collaborative research and integrate complementary interests to obtain innovative science and outstanding in-depth integrative multidisciplinary training possibilities. The scientific aims of this ITN proposal entitled ‘RADical reduction of OXidative stress in cardiovascular disease (RADOX)’ are to characterize the specific sources of reactive oxygen species (ROS) and their interaction in CVD and to use this knowledge to develop diagnostic tools for the detection and quantification of ROS and their subcellular targets. This will lead to new therapeutic strategies which modulate the activity of these specific sources of ROS. This RADOX consortium, containing 9 full partners (7 academic and 2 private) and 7 associate partners (1 academic and 6 private) will train 11ESR and 4ER. The mission of this ITN consortium is to create in a period of 4-years the future leaders in this field. Our trainees will receive unequaled multidisciplinary scientific and transferable skills training which will make them ready for leading positions in academia or industry. The training in this programme will be at 3 levels i.e. through research under supervision, transferable skills and secondments and will have a strong intersectoral, international and interdisciplinary character. Afterwards, the RADOX structure will serve as a European platform for outstanding doctoral training and oxidative stress research.;3935721;3935721;FP7-PEOPLE-2012-ITN;/MC-ITN;CHARITE - UNIVERSITAETSMEDIZIN BERLIN;DE;"THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;UNIVERSITEIT MAASTRICHT;UNIVERSITA DEGLI STUDI DI PADOVA;UNIVERSIDAD DE NAVARRA;Bayer Pharma AG;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;UNIVERSITY OF GLASGOW;KATHOLIEKE UNIVERSITEIT LEUVEN";"UK;NL;IT;ES;DE;BE";/LIF;1;0;0;1;0;0 111391;612889;MNEMERGE;ONG;FP7-SSH;SSH.2013.2.1-3;FP7;A Framework Model on MNE’s impact on global development challenges in emerging markets;2014-01-01;2016-12-31;;"MNEmerge Project aims to address the issues raised in this call together with a consortium that consists of top European universities, international organisations and multinational enterprises. We wish to provide a comprehensive framework, case study methodology and policy analysis of the activities of MNE and organisations operating in- and outside of EU. We are mostly interested on activities that take part in India, Brazil and Africa. The consortium has been an active contributor to the multinationals research and it has expertise on studying societal problems in emerging markets. The research will be carried out by an international, interdisciplinary team, involving researchers from Finnish, British and Dutch institutes. The issues studied in this project are varied but there is a common thread uniting all of its sub-themes; namely they all relate to how MNE activities in terms of one of the following: FDI, business functioning, technology and innovation strategies, corporate philanthropy or socially responsible investment, can contribute to the attainment of poverty alleviation, food security, health security and environmental security, which are intimately interlinked. The objectives of the project are: 1. Development of a framework to analyse MNE impact towards socio-economic development 2. Development of a model that describes the relationship between MNE, FDI and the economy 3. Role of public policies in supporting responsible business practises and the Millennium Declaration Goals 4. Case Studies to support the methodological framework model on health, environment and energy We identify modes of MNE collaboration with other societal stakeholders including the State, which permit the business sustainability while ensuring sustainable development of society as a whole with the ‘environment’ being a passive stakeholder. We will also develop tools and aids for decision making that can facilitate the implementation of the aforesaid recommendations.";2883384;2460024;FP7-SSH-2013-2;/CP-FP-SICA;LAPPEENRANNAN TEKNILLINEN YLIOPISTO;FI;"UNITED NATIONS UNIVERSITY;INESC P&D BRASIL - INSTITUTO DE ENGENHARIA DE SISTEMAS E COMPUTADORES, PESQUISA E DESENVOLVIMENTO DO BRASIL;THE UNIVERSITY OF BIRMINGHAM;COUNCIL FOR SCIENTIFIC AND INDUSTRIAL RESEARCH;UNIVERSITY OF KENT;BRUNEL UNIVERSITY LONDON;PUBLIC HEALTH FOUNDATION OF INDIA;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;TURUN YLIOPISTO;KING'S COLLEGE LONDON";"JP;BR;UK;GH;IN;FI";"/SOC;/POL";1;0;0;1;0;0 94830;238679;PHOSCHEMREC;ONG;FP7-PEOPLE;FP7-PEOPLE-ITN-2008;FP7;Recognition and Cleavage of Biological Phosphates – Molecular Recognition, Mechanism and Biomedical Applications;2010-07-01;2014-06-30;;Chemical Biology is a new, supradisciplinary field that unites the classically separate disciplines of Chemistry and Biology. This network is centred around understanding the central biological process of phosphate transfer and combines leading experts in synthetic chemistry, enzyme model building, kinetic analysis, protein chemistry and directed evolution in a concerted effort to gain a quantitative understanding of transition states that are key to understanding how biological systems can achieve phosphate transfer with unrivalled efficiency. The quantitative language (i.e. kinetic and molecular recognition studies) used to describe and improve natural enzymes unites all participants and provides the theme for our training programme on analysis of phosphate transfer catalysis. Training in this area is highly interdisciplinary in nature requiring a joint effort of chemists and biologists centred around mechanistic thinking, which is at the core of this proposal. Ultimately our understanding of this central bioreaction should lead to useful applications on the long term, e.g. as artificial nucleases, with potential roles in gene regulation, if efficient catalysis can be combined with selective recognition. This proposal is part of a long-term strategy aimed at developing reagents which act by binding or catalytically (thus as artificial enzymes) to interfere with the expression of specific genes. This can be achieved through selective binding eventually (but not necessarily) followed by cleaving the nucleic acid backbone. Crucially for therapeutic success these reagents have to be deliverd into the cell, which is why delivery issues are also addressed. The incorporation of industrial partners ensures that the full life-span of drug development is covered in this training programme.;2535051;2535051;FP7-PEOPLE-ITN-2008;/MC-ITN;THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;UK;"THE UNIVERSITY OF SHEFFIELD;UNIVERSITEIT GENT;OLIGOMER SCIENCES AB;AVARIS AB;UNIVERSITA DEGLI STUDI DI PADOVA;Wallac Oy;JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN;KAROLINSKA INSTITUTET;TURUN YLIOPISTO";"UK;BE;SE;IT;FI;DE";"/SCI;/EDU";1;0;0;1;0;0 111455;337822;TRANSMEM;ONG;FP7-IDEAS-ERC;ERC-SG-SH4;FP7;Fast transformation between episodic and semantic memories: Interactions between the hippocampal formation and related regions and their breakdown in Alzheimer’s disease;2014-02-01;2019-01-31;;"'Our memories define who we are and allow us to live independently. Conscious memory is commonly split into two components; “episodic memory” for events that are specific in time and place, and “semantic memory” for our conceptual knowledge about the world. The acquisition of both episodic and semantic memories depends upon the hippocampal formation (HF) and its interactions with other brain regions. Disruption to this brain system causes dramatic memory impairment, notably in the case of Alzheimer’s disease (AD). Current theories propose that episodic and semantic memory are either neuroanatomically inseparable, are independent, or that there is a gradual transformation from episodic to semantic over time. These theories fail to account for experimental evidence demonstrating the dynamic nature of human memory. TRANSMEM comprises a series of experiments designed to test a novel hypothesis; that semantic memory comprises high-level “structures” as well as “elements”, and memories for events are rapidly transformed between episodic and semantic representations and vice versa. In doing so, TRANSMEM will answer fundamental questions about the human mind, such as “Why do we remember certain things but not others?”, and “How do we store and retrieve our memories for the past?” Innovative methods, including the use of video clips and virtual reality, will be used to investigate memory for realistic materials. In a fully interdisciplinary approach, I will employ cutting-edge fMRI techniques and neuropsychology to establish how the HF interacts with other brain regions to mediate these transformations and how these processes break down in AD. Completion of the TRANSMEM project will lead to major advances in research and practice in experimental and clinical psychology, cognitive and behavioural neuroscience, neurology, and will be of interest to all scholars of the complexities of human mind.'";1169788;1169788;ERC-2013-StG;/ERC-SG;THE UNIVERSITY OF SUSSEX;UK;;;/SOC;1;0;0;1;0;0 111477;630199;ESOF 2014;ONG;FP7-SIS;SiS;FP7;Euroscience Open Forum 2014;2013-09-04;2014-11-03;;"Euroscience Open Forum (ESOF) is a biennial pan-European scientific meeting staged to provide an interdisciplinary forum for open debate and discussion on the role and future of scientific research, education and innovation. The ESOF meeting has taken place every second year in a major European city since 2004. ESOF 2014 will take place from the 21st to the 26th of June 2014 in Copenhagen with up to 5,000 delegates. To capture the essence of ESOF, the 2014 edition will be entitled ‘Science Building Bridges’. The bridge is a symbol of the vision of ESOF 2014: closing the distance between science and society, while forging a European scientific integration. ESOF 2014 will: • emphasize public debate, collective reasoning and reflection as intrinsic to the democratic community. • promote awareness of European science and engage the scientific community in Europe and globally. • honour the expectations of the various ESOF delegates by offering inspiring conference formats and state-of-the-art sessions addressing major global issues, e.g. health, resource management, and green economy. • increase the level of integration between the different target audiences – scientists, politicians, journalists, students and the public. All elements in the Copenhagen conference concept are part of an overall move towards a tighter integration of science, innovation communication and public engagement.";1368000;799000;FP7-Adhoc-2007-13;/CSA-SA;STYRELSEN FOR FORSKNING OG UDDANNELSE;DK;;;"/SCI;/SOC";1;0;0;1;0;0 95195;256718;AGRISCIMONT;ONG;FP7-REGPOT;REGPOT-2009-2;FP7;Fostering a Science-based Development of a sustainable Montenegrin Agriculture;2010-06-01;2013-11-30;;"The Biotechnical Faculty in Podgorica (BTF) is the only Montenegrin research institution focussed on agriculture. It performs a very wide range of researches in dialogue with decision-makers (partner of the Ministry of Agriculture for food control and policy drafting) and end-users (extension services). The AgriSciMont project (42 months) aims at strengthening BTF’s excellence through technological, human and partnership fostering and a reorganisation around 3 interdisciplinary research areas (food and feed safety, agro biodiversity conservation and agro-analyses) to converge towards excellence on “Fostering a Science-based Development of a Sustainable Montenegrin Agriculture”. The Action Plan is made of 6 WPs: Technological capacity-building; Human capacity-building and life-long learning; Mobility trainings; Excellence visibility and research strategy consolidation; Increase of visibility and Management. The AgriSciMont project is supported by different bodies and implies 5 collaborative partners. Each partner will actively participate to dissemination activities, management and mobility trainings. Measurable results are: new pieces of equipment; experienced researchers hired; scientific and support trainings lead; subscription to scientific magasines; two-way mobility trainings (31 researchers from BTF for 62 weeks; 14 people from partners for 14 weeks); intensified extension services; farmers’ days, workshops, one international conference; a long-term RTD strategy; attendance to international conferences; an open day; a web-site, regular newsletters; participation into the Food-Clustering initiative; interim and final reports. The expected impacts are an increase of scientific excellence on top EU and national priorities, an international active networking, a step towards a more integrated national and regional system, the recognition of BTF as the best agricultural research centre in Montenegro and the increase of its quality excellence, visibility in the ERA and attractiveness.";1247619,46;1112785,68;FP7-REGPOT-2010-5;/CSA-SA;JAVNA USTANOVA UNIVERZITET CRNE GORE PODGORICA;ME;;;/SCI;1;0;0;1;0;0 109078;331081;LOCALENERGY;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IEF;FP7;The potential of investments in energy efficiency and distributed generation to contribute to local development in Italy. Which role for local communities?;2014-02-01;2016-07-02;;This is a proposal for an interdisciplinary investigation into the potential of investments in energy efficiency and renewable generation to contribute to local development in Italy, with a focus on Italian ‘convergence objective’ regions (i.e. Calabria, Puglia, Sicilia and Campania). The project will consider several types of emerging business models for the implementation of energy measures at local level, their conditions for successful implementation and the relative role and implications for local actors and communities. It will analyse the case of implementing these emerging business models in the specific context of the territories targeted, exploring their appropriateness to respond to wider local communities development objectives and to maximise returns for the communities themselves. As such, the project will pay particular attention at emerging and innovative forms of implementation of community projects. An assessment of the target territory energy demand and generation potential (the energy map) coupled with engagement with the local stakeholders (i.e. local authorities and other public bodies, local communities as well as potential investors and technology suppliers in the private sector) will provide location specific data and information necessary to understand the socio-economic and energy context as well as specific local energy needs. Such information and the relationship developed with the main local stakeholders will be used for the identification of two to three case studies for which a detailed feasibility assessment of the investment in energy efficiency and renewable generation under different business models will be done, with the view of identifying best practice, barriers to implementation and assess replicability potential.;179739,6;179739,6;FP7-PEOPLE-2012-IEF;/MC-IEF;UNIVERSITA COMMERCIALE LUIGI BOCCONI;IT;;;/SCI;1;0;0;1;0;0 111398;613265;MEMOLA;ONG;FP7-SSH;SSH.2013.5.2-2;FP7;MEditerranean MOntainous LAndscapes: an historical approach to cultural heritage based on traditional agrosystems;2014-01-01;2017-12-31;;"'The project is an interdisciplinary approach to cultural landscapes of Mediterranean mountainous areas, taking as a central axis the historical study of two natural resources essential to generate agro-systems: water and soil. The proposal focuses on Sierra Nevada (Spain), Monti di Trapani (Italy), Colli Euganei (Italy) and Vjosa Valley (Albania). Landscapes and their structure are strongly conditioned by the need to ensure the livelihood of rural communities over time. Essentially they are the spatial representation of production and reproduction strategies of societies over time. Understanding them necessarily requires knowledge of the historical processes that have led to specific relationships with nature: mainly extraction and use of resources. These uses have largely shaped the medium, generating not only its shape, but also the culture that makes possible its management and maintenance. The various exploitation strategies have resulted in different landscapes and forms of cultural expression throughout Europe and the Mediterranean, but have also produced very important common areas. Agro-systems represent one of their greatest expressions. Agricultural traditions and the different ways of exploiting natural resources including management over time are crucial for conservation of the landscape and its ability to adapt to current global changes: globalisation and agrarian industrialisation, loss of peasant knowledge, loss of rural population and climate change. Conservation can be achieved through the exploitation of this heritage to generate environmental and cultural conservation strategies for sustainable development in rural areas; with the aim of protecting this cultural heritage and, at the same time, increasing and transmitting knowledge about it in order to benefit the local and wider European society.'";2940722,56;2499773;FP7-SSH-2013-2;/CP-FP;UNIVERSIDAD DE GRANADA;ES;"EACHTRA ARCHAEOLOGICAL PROJECTS LIMITED;THE UNIVERSITY OF SHEFFIELD;AGJENCIA E SHERBIMIT ARKEOLOGJIK;CENTRO UNESCO DE ANDALUCIA;ARQUEOANDALUSI ARQUEOLOGIA Y PATRIMONIO SL;UNIVERSITA DEGLI STUDI DI PALERMO;UNIVERSITA DEGLI STUDI DI PADOVA;AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS;UNIVERSIDAD DE CORDOBA;QENDRA E KERKIMEVE DHE PROMOVIMIT TE PEISAZHEVE HISTORIKO-ARKEOLOGJIKE SHQIPTARE";"IE;UK;AL;ES;IT";"/SOC;/POL";1;0;0;1;0;0 111525;337573;MADVIS;ONG;FP7-IDEAS-ERC;ERC-SG-SH4;FP7;Mapping the Deprived Visual System: Cracking function for prediction;2014-04-01;2019-03-31;;"One of the most striking demonstrations of experience-dependent plasticity comes from studies of blind individuals showing that the occipital cortex (traditionally considered as purely visual) massively changes its functional tuning to support the processing of non-visual inputs. These mechanisms of crossmodal plasticity, classically considered compensatory, inevitably raise crucial challenges for sight-restoration. The neglected relation between crossmodal plasticity and sight-recovery will represent the testing ground of MADVIS in order to gain important novel insights on how specific brain regions become, stay and change their functional tuning toward the processing of specific stimuli. The main goal of MADVIS is therefore to make a breakthrough on two fronts: (1) understanding how visual deprivation at different sensitive periods in development affects the functional organization and connectivity of the occipital cortex; and (2) use the fundamental knowledge derived from (1) to test and predict the outcome of sight restoration. Using a pioneering interdisciplinary approach that crosses the boundaries between cognitive neurosciences and ophthalmology, MADVIS will have a large impact on our understanding of how experience at different sensitive periods shapes the response properties of specific brain regions. Finally, in its attempt to fill the existing gap between crossmodal reorganization and sight restoration, MADVIS will eventually pave the way for a new generation of predictive surveys prior to sensory restoration.";1488987;1488987;ERC-2013-StG;/ERC-SG;UNIVERSITE CATHOLIQUE DE LOUVAIN;BE;UNIVERSITA DEGLI STUDI DI TRENTO;IT;/SOC;1;0;0;1;0;0 92416;242564;DOFOCO;ONG;FP7-IDEAS-ERC;ERC-SG-LS9;FP7;Do forests cool the Earth? Reconciling sustained productivity and minimum climate response with portfolios of contrasting forest management strategies;2010-02-01;2015-10-31;;"Forests, of which globally 70% are managed, play a particularly important role in the global carbon cycle. Recently, forest management became a top priority on the agenda of the political negotiations to mitigate climate change because forest plantations may remove atmospheric CO2 and if used for energy production, the wood is a substitute for fossil fuel. However, this political imperative is at present running well ahead of the science required to deliver it. Despite the key implications of forest management on: 1) the carbon-energy-water balance, and 2) production, recreation and environmental protection, there are no integrated studies of its effects on the Earth s climate. The overall goal of DOFOCO is to quantify and understand the role of forest management in mitigating climate change. Specifically, I want to challenge the current focus on the carbon cycle and replace it with a total climate impact approach. Hence, the whole forest management spectrum ranging from short rotation coppice to old-growth forests will be analyzed for its effects on the water, energy and carbon cycles. Climate response of forest will be quantified by means of albedo, evapotranspiration, greenhouse gas sources and sinks and their resulting climate feedback mechanisms. The anticipated new quantitative results will be used to lay the foundations for a portfolio of management strategies which will sustain wood production while minimizing climate change impacts. DOFOCO is interdisciplinary and ground breaking because it brings together state-of-the art data and models from applied life and Earth system sciences; it will deliver the first quantitative insights into how forest management strategies can be linked to climate change mitigation.";1296125;1296125;ERC-2009-StG;/ERC-SG;COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES;FR;;;"/ABI;/BIO;/LIF;/MED;/MBI";1;0;0;1;0;0 111390;612789;RICHES;ONG;FP7-SSH;SSH.2013.5.2-2;FP7;Renewal, Innovation and Change: Heritage and European Society;2013-12-01;2016-05-31;http://www.riches-project.eu/;"For many in 21st century Europe, Cultural Heritage (CH) is more about what it is than who we are: though enormously rich, this treasure is often locked away, or crumbling, or in a foreign language, or about a past which to many people - young , old, newcomers to Europe and settled inhabitants - seems of little relevance. But this is changing. As digital technologies permeate all of society, compelling us to rethink how we do everything, we ask questions: how can CH institutions renew and remake themselves? How should an increasingly diverse society use our CH? How may the move from analogue to digital represent a shift from traditional hierarchies of CH to more fluid, decentred practices? How, then, can the EU citizen, alone or as part of a community, play a vital co-creative role? What are the limitations of new technologies in representing and promoting CH? How can CH become closer to its audiences of innovators, skilled makers, curators, artists, economic actors? How can CH be a force in the new EU economy? RICHES will research answers to these questions by drawing together 10 partners from 6 EU countries and Turkey, experts from cultural institutions, public and national administrations, SMEs, the humanities and social sciences. Its interdisciplinary team will research the context of change in which European CH is transmitted, its implications for future CH practices, and the frameworks - cultural, legal, financial, educational, technical - to be put in place for the benefit of all audiences and communities in the digital age. RICHES will employ traditional and innovative research methods and tools; case studies will focus on copyright/IPR, the commoditisation of CH, performance-based CH; evidence-based reports, recommendations and guidelines will be produced for use by policy-makers, national agencies and CH practitioners. A rich dissemination programme including two major international conferences will ensure that the project has maximum outreach and impact.";3008086,44;2432356,72;FP7-SSH-2013-2;/CP-FP;COVENTRY UNIVERSITY;UK;"THE UNIVERSITY OF EXETER;PROMOTER SRL;Türkiye Cumhuriyeti Kültür ve Turizm Bakanl???;STICHTING NATIONAAL MUSEUM VAN WERELDCULTUREN;HANSESTADT ROSTOCK;SYDDANSK UNIVERSITET;STIFTUNG PREUSSISCHER KULTURBESITZ;STICHTING WAAG SOCIETY;FUNDACIO PRIVADA I2CAT, INTERNET I INNOVACIO DIGITAL A CATALUNYA";"UK;IT;TR;NL;DE;DK;ES";"/SOC;/POL";1;0;0;1;0;0 109924;603240;NMTRYPI;ONG;FP7-HEALTH;HEALTH.2013.2.3.4-2;FP7;New Medicines for Trypanosomatidic Infections;2014-02-01;2017-01-31;;"The infectious diseases burden imposed by the parasites of Trypanosomatidae family represents a huge problem on people’s lives in countries where these diseases are endemic. Problems associated with existing drugs include inefficient delivery, insufficient efficacy, excessive toxicity and increasing resistance. New drugs are urgently needed now and in the foreseeable future. The New Medicine for Trypanosomatid Infections (NMTrypI) consortium uses a highly interdisciplinary approach to optimize pteridine, benzothiazole and miltefosine derivatives, as well as natural products against Trypanosomatids. The lead compounds target mechanisms that are associated with protozoa virulence and pathogenicity. The major objectives of this 3-year project are: i) development of drug leads which may be used in combination with a known or an investigational drugs, by using a common drug discovery platform established by experts in their respective fields, ii) development of pharmacodynamic biomarkers enabling the proteomic profiling of compound efficacy and early identification of drug resistance. NMTrypI addresses sleeping sickness, leishmaniasis, and Chagas disease. The partners are SMEs (5) and academics (8) in Europe and in disease-endemic countries (Italy, Greece, Portugal, Sudan, and Brazil). The new platform enables high throughput screening of compound libraries, lead development, testing in relevant animal models, as well as toxicology and safety testing. NMTrypI will translate drug leads into drug candidacy through 6 scientific work packages (WPs1-6) supported by two transversal WPs dedicated to project dissemination and management. The major strength of the consortium lies in the complementary partners’expertise and the integrated platform that will provide: - at least 1-2 innovative, less toxic and safer drug candidates for Trypanosomatid infections compared to existing ones, - early phase biomarkers for efficacy prediction (overall improved efficacy and safety)";7639176,11;5901411,15;FP7-HEALTH-2013-INNOVATION-1;/CP-FP;UNIVERSITA DEGLI STUDI DI MODENA E REGGIO EMILIA;IT;"Interface Europe;INSTITUTO DE BIOLOGIA MOLECULAR E CELULAR-IBMC;Universit? degli Studi di Siena;FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.;NATIONAL CENTER FOR RESEARCH;HITS GGMBH;TYDOCK PHARMA S.r.l;Hypha Discovery Limited;UNIVERSIDAD COMPLUTENSE DE MADRID;CENTRO NACIONAL DE PESQUISA EM ENERGIA E MATERIAS ASSOCIACAO PRIVADA;European ScreeningPort GmbH;ETHNIKO IDRYMA EREVNON;Bernhard Nocht Institute for Tropical Medicine";"BE;PT;IT;DE;SD;UK;ES;BR;EL";/LIF;1;0;0;1;0;0 111306;612617;GOVDIV;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IRSES;FP7;Multilevel governance of cultural diversity in a comparative perspective: EU-Latin America;2014-01-01;2017-12-31;;"The overall aim of this proposal is to create a transnational interdisciplinary research and training network between European and Latin American Universities and Research centres in order to promote transfer of knowledge and to produce innovative research in the field of the multilevel governance of cultural diversity in a comparative perspective. The governance of cultural diversity is a key issue for contemporary Europe. Accommodating increased cultural diversity by balancing the recognition of differences with the promotion of equal participation in the common public sphere is a task that will, for the foreseeable future, be with us to stay. The proposal will represent a crucial moment for a stronger institutionalisation of the existing collaborations among the partner institutions, giving a systematic character to the transfer of knowledge on the issue of cultural diversity, through methodological workshops, which will clarify definitions and conceptualizations, through the implementation of comparative research, the implementation of joint courses (Master programs, doctoral studies) and the launching of a scientific journal in English. The comparative research projects implemented will focus on the relations between, on one side, the institutional framework and the governments’ policies, and, on the other, the empirical dynamics of the cultural construction, social formation and political mobilization of collective identities, deployed by migrants, ethno-national minorities, religious minorities, indigenous peoples. The proposal’s research outcomes will enable a better understanding of the complex dynamics in plural and multi-ethnic societies and may possibly suggest new paths for policies and governance at national and at EU-level.";602700;602700;FP7-PEOPLE-2013-IRSES;/MC-IRSES;INSTITUTO UNIVERSITARIO DE LISBOA;PT;"UNIVERSIDADE DO MINHO;UNIVERSITA DEGLI STUDI DI FIRENZE;UNIVERSIDAD DE GRANADA;UNIVERSITE PARIS III SORBONNE NOUVELLE;UNIVERSIDAD DE SEVILLA";"PT;IT;ES;FR";/LIF;1;0;0;1;0;0 103972;299972;THERAPY OPTIONS THD;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IEF;FP7;Neurotransmitter synthesis disorders: towards a therapeutic correction;2012-10-01;2014-09-30;;'The present postdoctoral project to be carried out by Dr. Ana Jorge Finnigan at the Department of Biomedicine, University of Bergen, is integrated in the research programs carried out at Research group Biorecognition, leaded by Professor Aurora Martinez. The postdoctoral project integrates methods spanning the structural and functional characterization of complexes of tyrosine hydroxylase (TH) with proteins and membranes, and the regulation of the activity and localization of TH by small ligands, both in cells and animal models. The activities are organized in an interdisciplinary set-up of expertise and methodology managed by the applicant lab and a network of collaborators. TH catalyzes the hydroxylation of L-Tyr to DOPA, the rate-limiting step in the synthesis of catecholamine neurotransmitters and hormones in brain and neuroendocrine tissues. Due to the high relevance of well-regulated catecholamine synthesis and protein-membrane interactions in human health and neurological disease, the project is expected to contribute with novel understanding of pathogenic mechanism affecting TH stability and regulation as well as with novel therapeutic approaches aiming correction of TH misfolding and mislocalization. The therapuetical tools developed through this project may even be of application to social burden diseases such as Parkinson's disease.';208353,6;208353,6;FP7-PEOPLE-2011-IEF;/MC-IEF;UNIVERSITETET I BERGEN;NO;;;/SCI;1;0;0;1;0;0 111363;326930;ITREGDIFFERENTIATION;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IEF;FP7;Kinetic analysis of molecular profiles during human induced regulatory T cell (iTreg) differentiation: an integrative study;2014-01-01;2015-12-31;;Regulatory T cells (Tregs) suppress other immune cells and, thus, are critical mediators of peripheral self-tolerance, preventing autoimmune disease but hampering tumor rejection. Therapeutic manipulations of Treg number and function are therefore subject to numerous clinical investigations. First in-man trials of adoptive Treg transfer to prevent graft-versus-host disease showed very promising outcomes. Yet, the number of naturally occurring Tregs (nTregs) is minute, encouraging the complementary approach of inducing Tregs (iTregs) from naive T cell precursors. Reinforcing this concept, there are several studies in mice indicating that iTreg transfer may be superior to nTreg transfer. Moreover, iTregs are generated in vivo and ample evidence corroborates that iTregs exert non-redundant functions to maintain health. However, the molecular mechanisms governing iTreg generation in humans are incompletely understood and procedures for human iTreg generation are controversial. Here we will therefore establish and compare different protocols of human iTreg generation juxtaposed with deep molecular profiling using RNA sequencing and DNA methylation analysis. The time-dependent transcriptomic and epigenetic data, capturing molecular events during generation of iTregs, will be subject to bioinformatics analysis. Our integrative analysis will present the first global hierarchical molecular map of pathways driving human iTreg differentiation, which in addition will provide a molecular scaffold enabling deeper analyses to resolve molecular events independent and dependent of established factors. Furthermore, the biological role of novel transcripts, splice variants and epigenetic regulations will be validated biologically by gene knockdown or overexpression experiments. Our interdisciplinary analysis of the molecular mechanisms ruling human iTreg generation may have important implications for our understanding and ability to treat cancer, autoimmune and inflammatory diseases.;197811,6;197811,6;FP7-PEOPLE-2012-IEF;/MC-IEF;KAROLINSKA INSTITUTET;SE;;;/SCI;1;0;0;1;0;0 111285;339220;AtomicGaugeSimulator;ONG;FP7-IDEAS-ERC;ERC-AG-PE2;FP7;Classical and Atomic Quantum Simulation of Gauge Theories in Particle and Condensed Matter Physics;2014-02-01;2019-01-31;;Gauge theories play a central role in particle and condensed matter physics. Heavy-ion collisions explore the strong dynamics of quarks and gluons, which also governs the deep interior of neutron stars, while strongly correlated electrons determine the physics of high-temperature superconductors and spin liquids. Numerical simulations of such systems are often hindered by sign problems. In quantum link models - an alternative formulation of gauge theories developed by the applicant - gauge fields emerge from discrete quantum variables. In the past year, in close collaboration with atomic physicists, we have established quantum link models as a framework for the atomic quantum simulation of dynamical gauge fields. Abelian gauge theories can be realized with Bose-Fermi mixtures of ultracold atoms in an optical lattice, while non-Abelian gauge fields arise from fermionic constituents embodied by alkaline-earth atoms. Quantum simulators, which do not suffer from the sign problem, shall be constructed to address non-trivial dynamics, including quantum phase transitions in spin liquids, the real-time dynamics of confining strings as well as of chiral symmetry restoration at finite temperature and baryon density, baryon superfluidity, or color-flavor locking. New classical simulation algorithms shall be developed in order to solve severe sign problems, to investigate confining gauge theories, and to validate the proposed quantum simulators. Starting from U(1) and SU(2) gauge theories, an atomic physics tool box shall be developed for quantum simulation of gauge theories of increasing complexity, ultimately aiming at 4-d Quantum Chromodynamics (QCD). This project is based on innovative ideas from particle, condensed matter, and computational physics, and requires an interdisciplinary team of researchers. It has the potential to drastically increase the power of simulations and to address very challenging problems that cannot be solved with classical simulation methods.;1975242;1975242;ERC-2013-ADG;/ERC-AG;UNIVERSITAET BERN;CH;;;"/PSE;/SCI";1;0;0;1;0;0 101025;283158;AfriCAN Climate;ONG;FP7-ENVIRONMENT;ENV.2011.5.1.0-1;FP7;Uptake of Climate related Research Results through Knowledge Platforms with African Collaboration Partners;2011-10-01;2014-09-30;;"The main aim of the AfriCAN Climate project is the development, operation and promotion of a web-based Knowledge Platform for efficient dissemination of climate change research results and good practices, to encourage users for uptake of success stories and research knowledge in new projects. Thereby, the project will contribute to mitigate climate change impacts on African regions and help communities to adapt to the changing climatic conditions. Emphasis will be placed on a variety of innovative and creative web functionalities (“e-tools”) when developing the interactive, multimedia, pan-continental, multi-lingual and interdisciplinary AfriCAN Climate Platform. The new platform visitors, the already registered users and the members of the online communities will be facilitated by the editorial team to actively participate in knowledge exchange and uptake of research results. The high profile consortium includes a large variety of experienced EU and African organizations, corresponding to the diversity of target audience addressed by the call. The experts in the consortium achieve full thematic, linguistic and geographical coverage to serve the African continent’s climate change knowledge needs. They will jointly build and continuously update a knowledgebase to feed the platform. Country fact sheets on climate change impacts will be developed for all 54 African countries. Strategic networking meetings with information multipliers and FP7 National Contact Points will be held on a regular base to encourage them to become active on the Platform by building climate change interest communities, or joining existing communities. On a yearly base, large promotional events will be organized, hosting the AfriCAN Climate Music/Art and Good Practice Award. Technical tours to good practice sites and workshops on uptake of lessons learn in good practice projects and financing will complement the networking activities and improve South-South Cooperation amongst African regions.";1270903;999884,25;FP7-ENV-2011;/CSA-SA;WIRTSCHAFT UND INFRASTRUKTUR GMBH & CO PLANUNGS KG;DE;"IGAD CENTRE FOR CLIMATE PREDICTION AND APPLICATION;INTERNATIONAL CENTRE FOR RESEARCH IN AGROFORESTRY;ENDA Tiers Monde;IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE;PRACTICAL ACTION;FOOD AGRICULTURE AND NATURAL RESOURCES POLICY ANALYSIS NETWORK;UNIVERSITY OF THE WITWATERSRAND JOHANNESBURG;DANMARKS TEKNISKE UNIVERSITET;PAU EDUCATION SL";"KE;SN;UK;ZA;DK;ES";/ENV;1;0;0;1;0;0 110613;336803;ENCODE;ONG;FP7-IDEAS-ERC;ERC-SG-LS2;FP7;Design Principles in Encoding Complex Noisy Environments;2014-02-01;2019-01-31;;"Animals constantly face complex environments consisted of multiple fluctuating cues. Accurate detection and efficient integration of such perplexing information are essential as animals’ fitness and consequently survival depend on making the right behavioral decisions. However, little is known about how multifaceted stimuli are integrated by neural systems, and how this information flows in the neural network in a single-neuron resolution. Here we aim to address these fundamental questions using C. elegans worms as a model system. With a compact and fully-mapped neural network, C. elegans offers a unique opportunity of generating novel breakthroughs and significantly advance the field. To study functional dynamics on a network-wide scale with an unprecedented single-neuron resolution, we will construct a comprehensive library of transgenic animals expressing state-of-the-art optogenetic tools and Calcium indicators in individual neurons. Moreover, we will study the entire encoding process, beginning with the sensory layer, through integration in the neural network, to behavioral outputs. At the sensory level, we aim to reveal how small sensory systems efficiently encode the complex external world. Next, we will decipher the design principles by which neural circuits integrate and process information. The optogenetic transgenic animals will allow us interrogating computational roles of various circuits by manipulating individual neurons in the network. At the end, we will integrate the gathered knowledge to study how encoding eventually translates to decision making behavioral outputs. Throughout this project, we will use a combination of cutting-edge experimental techniques coupled with extensive computational analyses, modelling and theory. The aims of this interdisciplinary project together with the system-level approaches put it in the front line of research in the Systems Biology field.";1498400;1498400;ERC-2013-StG;/ERC-SG;THE HEBREW UNIVERSITY OF JERUSALEM;IL;;;"/BIO;/LIF";1;0;0;1;0;0 111402;613344;MIME;ONG;FP7-SSH;SSH.2013.5.2-1;FP7;MIME - MOBILITY AND INCLUSION IN MULTILINGUAL EUROPE;2014-03-01;2018-08-31;;"Using an innovative interdisciplinary approach, MIME will generate an organised body of policy-relevant propositions addressing the full range of questions raised in the call. Our aim is to identify the language policies and strategies that best combine “mobility” and “inclusion”. MIME emphasises complementarity between disciplines, and brings together researchers from sociolinguistics, political science, sociology, history, geography, economics, education, translation studies, psychology, and law, who all have longstanding experience in the application of their discipline to language issues. The diverse concepts and methods are combined in an analytical framework designed to ensure their practice-oriented integration. MIME identifies, assesses and recommends measures for the management of trade-offs between the potentially conflicting goals of mobility and inclusion in a multilingual Europe. Rather than taking existing trade-offs as a given, we think that they can be modified, both in symbolic and in material/financial terms, and we argue that this objective can best be achieved through carefully designed public policies and the intelligent use of dynamics in civil society. Several partners have been involved in successful FP6 research, and key advances achieved there will guide the MIME project: languages are viewed as fluid realities in a context of high mobility of people, goods, services, and knowledge, influencing the way in which skills and identities are used and constantly re-shaped. The project integrates these micro-level insights into a macro-level approach to multilingual Europe. MIME results will be made widely available through a creative approach to dissemination, including training modules and the MIME Stakeholder Forum, allowing for sustained dialogue between academics, professional associations and local/regional authorities. The project culminates in a consensus conference where recommendations based on the project findings are adopted.";6392756,03;4999998;FP7-SSH-2013-1;/CP-IP;UNIVERSITE DE GENEVE;CH;"SVEUCILISTE JOSIPA JURJA STROSSMAYERA U OSIJEKU FILOZOFSKI FAKULTET;UNIVERSITAT ROVIRA I VIRGILI;MAGYAR TUDOMANYOS AKADEMIA TARSADALOMTUDOMANYI KUTATOKOZPONT;SCIPROM S?rl;VRIJE UNIVERSITEIT BRUSSEL;FONDATION NATIONALE DES SCIENCES POLITIQUES;UNIVERSITE DE REIMS CHAMPAGNE-ARDENNE;UPPSALA UNIVERSITET;UNIVERSITY OF LIMERICK;UNIVERSITAET LEIPZIG;UNIVERSITATEA DIN ORADEA;fondation Observatoire de la Finance;UNIVERSIDADE DO ALGARVE;HUMBOLDT-UNIVERSITAET ZU BERLIN;LATVIJAS UNIVERSITATE;UNIVERSITA' DEGLI STUDI DI MILANO-BICOCCA;UNIVERSITAET AUGSBURG;KATHOLIEKE UNIVERSITEIT LEUVEN;THE UNIVERSITY OF EDINBURGH;UNIVERZA V LJUBLJANI;UNIVERSITEIT VAN AMSTERDAM";"HR;ES;HU;CH;BE;FR;SE;IE;DE;RO;PT;LV;IT;UK;SI;NL";"/SOC;/POL";1;0;0;1;0;0 93095;238646;EDUWEL;ONG;FP7-PEOPLE;FP7-PEOPLE-ITN-2008;FP7;Education as Welfare - Enhancing opportunities for socially vulnerable youth in Europe;2010-01-01;2014-08-31;;The ITN 'Education as Welfare - Enhancing opportunities for socially vulnerable youth in Europe' aims to consolidate research on education and welfare and evaluate its capacity to tackle the multiple challenges and pressures a large proportion of young people in Europe faces. In examining the welfare dimensions of educational settings and the educational dimensions of welfare services, it integrates welfare and educational perspectives into a coherent approach for theoretical analysis and public policy. By focusing on universal conditions of human development, this approach warrants international applicability. It produces knowledge that facilitates the enablement and social integration of young people facing economic, social and personal barriers after leaving compulsory schooling. The scientific objective of the research and training programme is to identify factors with which to extend young people’s opportunities and capabilities in work, autonomy and participation -- the central dimensions of welfare. The ITN will combine and synergise the interdisciplinary research experience and professional capacities of leading European university departments and social, economic and political actors. Alongside their own research projects, the Early-Stage Researchers will design and conduct a comparative Education-as-Welfare survey that will serve as one fundament of their methodological training. The five non-university partners will especially ensure the dissemination of the findings to education and welfare policymakers. The added value of the ITN consists in promoting a new type of governance of education and welfare that transcends traditional national borders. It will develop a theoretically advanced, empirically measurable and internationally comparable conception of education as welfare that the excellent experts in human service provision it has trained will be able to apply from an innovative, analytically sound and practically applicable perspective.;3041210;3041210;FP7-PEOPLE-ITN-2008;/MC-ITN;UNIVERSITAET BIELEFELD;DE;"UNIWERSYTET IM. ADAMA MICKIEWICZA W POZNANIU;INSTITUTE OF EDUCATION, UNIVERSITY OF LONDON;UNIVERSITA DEGLI STUDI DI FIRENZE;Istituto Universitario di Studi Superiori di Pavia;UMEA UNIVERSITET;THE UNIVERSITY OF NOTTINGHAM;INSTITUT SYNDICAL EUROPEEN;HAUTE ECOLE SPECIALISEE DE SUISSE OCCIDENTALE;GOETEBORGS UNIVERSITET;FONDATION DE L'INSTITUT DE RECHERCHE DE L'INTERNATIONALE DE L'EDUCATION";"PL;UK;IT;SE;BE;CH";"/SCI;/EDU";1;0;0;1;0;0 100923;293444;DISSECTING BRCA2;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-CIG;FP7;Dissecting the role of BRCA2 in the DNA damage response and exploiting its parts for anticancer therapy;2011-11-01;2015-10-31;;"Mutations in the tumor suppressor gene, BRCA2, cause susceptibility to breast and ovarian cancer. BRCA2 protein is required for homologous recombinational DNA repair (HRR), the predominant mechanism employed by cells to accurately repair DNA double-stranded breaks (DSBs). In humans, the central player of the HRR process is RAD51; it catalyzes the DNA strand exchange that results in the repaired DNA. Through its interaction with RAD51, BRCA2 controls RAD51 function by locating it to the DSBs. Thus, defects in BRCA2 lead to genomic instability, a hallmark of tumorigenesis. During my postdoc, I have revealed important aspects of BRCA2 protein, the regulatory function of the BRC repeats of BRCA2 on RAD51 DNA binding selectivity as well as contribute to the first biochemical characterization of the full-length BRCA2 protein. In an interdisciplinary approach and, as an independent researcher, my main goals are to: 1) Reveal new roles of BRCA2 by mapping the interactions with other proteins: For example, recently a DMC1 interacting site on BRCA2 has been reported involving BRCA2 in meiotic recombination. 2) Better understand the HRR process: Evidences from the BRCA2 homologue in fungus point to another DNA binding site in BRCA2; finding this region in the human protein may decipher important aspects of the regulation of HRR that remain elusive. 3) Exploit regions of the protein as a therapeutic tool for tumor treatment. We will use peptides derived from BRCA2 protein that are involved in interactions with key proteins in the HRR pathway to block this pathway in tumors cells. 4) Develop new strategies to carry these peptides to the targeted tumor cells. The combination of basic science (aims 1, 2) and applied science (aims 3, 4) approaches proposed here provides a framework to understand the connection between different DNA damage response mechanisms that in turn, will lead to develop new anticancer therapies.";100000;100000;FP7-PEOPLE-2011-CIG;/MC-CIG;INSTITUT CURIE;FR;;;/SCI;1;0;0;1;0;0 98242;276868;NEURO-MIR-NETWORKS;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-RG;FP7;MicroRNA Networks in Neuronal Development and Plasticity;2011-03-01;2015-02-28;;"microRNAs (miRNAs) are novel gene circuitry regulators with an elusive role in neuronal development and plasticity. These small non-coding RNA molecules may explain some of the dysfunctional mechanisms in mental disorders, and are promising targets for diagnosis and treatment of neuropsychiatric disorders. I have recently identified pre-synaptically enriched miRNAs, of which miR-338 was found to modulate the mitochondrial function. This fellowship will allow me to use the knowledge I have gained on the roles of synaptic translation in neuronal development and plasticity as a Research Associate in USA and implement that knowledge to Europe. The three main objectives of my proposed research are: (1) to identify candidate miRNAs differentially expressed during hippocampal development and plasticity; (2) to delineate miRNA’s regulatory role on local protein synthesis which is required for synaptic plasticity; and (3) to determine the functions of miRNAs in neuronal development and plasticity. To address objectives 1 and 2, I will employ deep-sequencing to identify miRNA genes differentially and spatially expressed during experience-dependent synaptic plasticity in the rat hippocampus and its synaptic compartments, respectively, and carry out computational prediction followed by experimental confirmations to identify miRNAs involved in synaptic function. In objective 3, I will investigate miRNA function in different forms of synaptic plasticity using cell biological approaches combined with in vivo behavioral experiments. I anticipate that my interdisciplinary research approach will define the role of miRNAs in synaptic plasticity and memory storage. The research proposed is innovative and significant because it may establish a new avenue of research on synaptic pathophysiology in mental disorders, and may provide the European society with cutting-edge technology with the potential to generate new miRNA-based therapies to treat nervous system disorders.";100000;100000;FP7-PEOPLE-2010-RG;/MC-IRG;STICHTING KATHOLIEKE UNIVERSITEIT;NL;;;/SCI;1;0;0;1;0;0 98087;259166;HIGHWIND;ONG;FP7-IDEAS-ERC;ERC-SG-PE7;FP7;"Simulation, Optimization and Control of High-Altitude Wind Power Generators";2011-03-01;2017-02-28;;"A new class of large scale wind power generators shall be investigated via mathematical modelling, computer simulation and multidisciplinary optimization methods. The underlying technical idea is to use fast flying tethered airfoils that fly in altitudes of several hundred meters above the ground. They will perform specially controlled loops accompanied by line length and line tension variations, that are used to drive a generator on the ground. Being a high risk / high gain technology, the applicant believes that the main focus in the first development years should not be on building large and expensive experimental setups (as some courageous experimentalists currently do in Europe and the US), but on mathematical modelling, computer simulation and optimization studies, accompanied by only small scale experiments for model and control system validation. This will help finding optimal system designs before expensive and potentially dangerous large scale systems are built. The research requires an interdisciplinary collaboration of scientists from mathematical, mechanical, aerospace, and control engineering, as well as from the computational sciences. At the end of the project, a small scale, automatically flying prototype shall be realized, accompanied by validated and scalable mathematical models and a toolbox of efficient computational methods for simulation and multidisciplinary optimization of high altitude wind power systems. If successful, the project will help to establish this new type of wind power generator that might provide electricity more cheaply than fossil fuels and is deployable at considerably more sites than conventional windmills.";1499800;1499800;ERC-2010-StG_20091028;/ERC-SG;ALBERT-LUDWIGS-UNIVERSITAET FREIBURG;DE;KATHOLIEKE UNIVERSITEIT LEUVEN;BE;"/PSE;/AER;/SPA";1;0;0;1;0;0 93966;247404;MESOLIGHT;ONG;FP7-IDEAS-ERC;ERC-AG-ID1;FP7;Mesoscopic Junctions for Light Energy Harvesting and Conversion;2010-03-01;2015-02-28;;Research will focus on the generation of electric power by mesoscopic solar cells, a domain where the PI has an outstanding track record and leadership on the global scale. The target is to increase the photovoltaic conversion efficiency from currently 11 to over 15 percent rendering these new solar cells very attractive for applications in large areas of photovoltaic electricity production. The approach to reach this challenging target is highly creative and has a strongly interdisciplinary character. Successful implementation of the project goals is assured by the vast experience and know how of the PI and his team in the key areas of the project. The project is divided in four work packages. The first three introduce creative new concepts to enhance substantially the performance of single-junction dye sensitized nanocrystalline devices, while the fourth addresses multi-junction cells and photon up-conversion systems. The tasks to be accomplished comprise 1) The theoretically assisted conception and synthesis of new molecular sensitizers to extend the spectral response of dye sensitized photovoltaic cells into the near IR up to 900 nm, increasing substantially the short circuit photocurrent of the solar cell. 2) The implementation of highly innovative mesoscopic oxides structures to support the molecular dye or quantum dot and collect the photo-generated charge carriers. 3) The introduction of smart amphiphilic molecular insulators and ultra-thin ceramic barriers at the mesoscopic junction in order to retard the interfacial electron-hole recombination and 4) The exploration of radically new cell embodiments based on multi-junction tandem cells and photon up-conversion schemes, whose solar to electric power conversion efficiency can be raised beyond the Shockley-Queiser limit of 32 percent.;2046000;2046000;ERC-2009-AdG;/ERC-AG;ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE;CH;;;/SCI;1;0;0;1;0;0 101825;289192;SOCIOEC;ONG;FP7-KBBE;KBBE.2011.1.2-10;FP7;Socio economic effects of management measures of the future CFP;2012-03-01;2015-02-28;http://www.socioec.eu/;"SOCIOEC is an interdisciplinary, European wide project bringing together scientists from several fisheries sciences with industry partners and other key stakeholders to work in an integrated manner on solutions for future fisheries management, that can be implemented at a regional level. The central concept is to provide a mechanism for developing measures that are consistent with the overarching sustainability objectives of the EU, and that can provide consensus across all stakeholders. The first step will be to develop a coherent and consistent set of management objectives, which will address ecological; economic and social sustainability targets. The objectives should be consistent with the aims of the CFP, MSFD and other EU directives, but they should also be understandable by the wider stakeholder community and engage their support. This will then lead to the proposal of a number of potential management measures, based on existing or new approaches. The second step will be to analyze the incentives for compliance provided by these measures. In particular, we will examine fisher’s responses and perceptions of these measures, based on historical analysis as well as direct consultation and interviews. This project part will also examine how the governance can be changed to facilitate self- and co-management to ensure fisher buy-in to promising management measures. In particular, the project will focus on the interpretation of overarching (i.e. EU) objectives in local and regional contexts. Finally, the project will examine the impacts of the management measures that emerge from this process, particularly in terms of their economic and social impacts. The IA analysis will be integrated by evaluating the proposed measures against the criteria of effectiveness, efficiency and coherence. Special attention will be paid in evaluating the proposed management measures’ performance in terms of their ability to achieve the general and specific ecological objectives.";3829884,4;2999939;FP7-KBBE-2011-5;/CP-TP;JOHANN HEINRICH VON THUENEN-INSTITUT, BUNDESFORSCHUNGSINSTITUT FUER LAENDLICHE RAEUME, WALD UND FISCHEREI;DE;"DENNIS NISSEN;UNIVERSITY OF PORTSMOUTH HIGHER EDUCATION CORPORATION;KUTTERFISCH-ZENTRALE GMBH;NATIONAL UNIVERSITY OF IRELAND GALWAY;Marine Law and Ocean Policy Research Services Ltd;AquaTT UETP Ltd;NISEA SOCIETA COOPERATIVA;HELLENIC CENTRE FOR MARINE RESEARCH;UNIVERSITE DE BRETAGNE OCCIDENTALE;KOBENHAVNS UNIVERSITET;CLODIAMARE1 SC;CHRISTIAN-ALBRECHTS-UNIVERSITAET ZU KIEL;MARINE INSTITUTE;KARADENIZ TEKNIK UNIVERSITESI;PECHEURS DE MANCHE ET D'ATLANTIQUESA;ISTITUTO DI RICERCHE ECONOMICHE PERLA PESCA E L'AQUACOLTURA IREPA ONLUS ASSOCIAZIONE;DANMARKS TEKNISKE UNIVERSITET;INSTITUT FRANCAIS DE RECHERCHE POUR L'EXPLOITATION DE LA MER;MEDITERRANEAN AQUAFARM SERVICES SL;FUNDACION AZTI - AZTI FUNDAZIOA;A/S LAESO FISKEINDUSTRI;HASKOLI ISLANDS;AALBORG UNIVERSITET;STICHTING WAGENINGEN RESEARCH;JRC -JOINT RESEARCH CENTRE- EUROPEAN COMMISSION";"DE;UK;IE;IT;EL;FR;DK;TR;ES;IS;NL;BE";/ECO;1;0;0;1;0;0 97017;264057;MARINELIVE;ONG;FP7-REGPOT;REGPOT;FP7;Marine Electrical Initiative;2010-12-15;2014-06-14;;"'MARINELIVE is an initiative both at a national and European level, aiming at establishing a Centre of Excellence in the field of Marine Electrical Engineering at the School of Naval Architecture & Marine Engineering of the National Technical University of Athens (NAME-NTUA), as well as at building a European community of 'All Electric Ship' (AES) research and technology. MARINELIVE, focusing on the AES technology, contributes towards designing safer and more environmentally friendly ships. In the course of MARINELIVE, the development of NAME-NTUA will build upon the formation of a balanced interdisciplinary research team covering all major aspects of AES research, i.e. electric machines and grids, ship automation and control, as well as propulsion systems and prime movers. The objectives of MARINELIVE will be realized via: (a) recruitment of experienced researchers in the fields of power electrical engineering, automation and controls, and prime movers (b) two-way exchanges of know-how and experience with leading European academic and industrial Institutions (c) acquisition of a Grid Emulator and a Power Management System, and upgrade of current computational infrastructures (d) organisation of international workshops and conferences on Propulsion Systems, Electric Machines and Converters, Prime Movers, Automation and Control, Ship Electric Grids, and Power Management Systems, for AES applications (e) spreading excellence via a series of dissemination activities, including organisation of Open-Days, and participation in international exhibitions and conferences. MARINELIVE activities will contribute towards: (a) substantially enhancing the capacity of NAME-NTUA to perform world-class research in Marine Electrical Engineering, and strengthening the School’s leading position in Naval Architecture and Marine Engineering (b) supporting European Research and Development activities related to “All Electric Ship” technology, and its adoption by the maritime industry.'";2153241,98;1939741;FP7-REGPOT-2010-1;/CSA-SA;NATIONAL TECHNICAL UNIVERSITY OF ATHENS - NTUA;EL;;;"/SCI;/ITT";1;0;0;1;0;0 98572;274903;SELEFLU;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-IIF;FP7;Synthesis and Evaluation of 18F-Labelled N-F Reagents;2011-09-12;2013-09-11;;The overall objective of this proposal is to capitalise on our expertise in synthetic and fluorine organic chemistry by undertaking a research programme aimed at exploring the value of 18F-labelled N-F reagents. Upon completion of the proposed research programme, we hope to provide 18F-radiochemists with a toolbox filled with novel 18F-radiosynthetic strategies. The unconventional and innovative methods that we will investigate are designed to address well recognised pending problems in 18F-radiolabelling and to offer unprecedented radiosynthetic routes to access 18F-labelled targets. The impact of the novel radiochemistry we propose to develop is far reaching to advance Positron Emission Tomography (PET). PET is a non-invasive molecular imaging technique used clinically for diagnostic purpose and drug discovery. This expanding highly interdisciplinary area of research relies on radiotracers labelled with a positron-emitting radioisotope. 18F-Labelled molecules are frequently used because of the advantageous properties of the 18F in comparison with other non-metallic radioisotopes. For rapid progress, the radiochemistry available for 18F-labelling should be sufficiently diverse for any designed 18F-radiotracers to be accessible regardless of the point of attachment of the 18F-label. To date, this is far from the reality, as current methodologies to construct 18F-labelled molecules present with limitations. The emphasis of this proposal is on the development and use of 18F-labelled N-F reagents of high specific activity for electrophilic fluorination. These reagents should allow for the production of 18F-labelled radiotracers in high radiochemical yield, purity and specific activity.;201049,6;201049,6;FP7-PEOPLE-2010-IIF;/MC-IIF;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;UK;;;"/SOC;/COO";1;0;0;1;0;0 101707;289161;TALENT;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-ITN;FP7;Training for cAreer deveLopment in high-radiation ENvironment Technologies;2012-01-01;2015-12-31;;"TALENT is a 4-year multi-site training network aiming at career development of young researchers on design, construction, manufacturing, testing and commissioning of innovative radiation hard detector modules and novel scientific instruments. TALENT provides, to 15 ESRs and 2 ERs, training for deep understanding of the complexity of scientific instrument building from theoretical design until industrial manufacturing cost efficiency considerations. The network consists of 9 academic institutions and 8 industrial companies of excellence, providing the researchers a multicultural, truly stimulating and interdisciplinary learning environment. The 2006 report of ESFRI and the European Strategy for Particle Physics set the CERN Large Hadron Collider (LHC) Upgrade and enhancement of intersectoral R&D as priorities to keep the leading high energy physics facilities and expertise of Europe at the world-class level. TALENT will make substantial advancements into these objectives. The research program significantly contributes into CERN ATLAS R&D project, the Insertable B-layer (IBL). Furthermore, IBL’s innovative detector modules and instrumentation are already showing major potential for industrial applications in satellite instruments, X-ray systems, sensor technologies, medical imaging and cancer therapy. To enhance intersectoral R&D and training collaboration as well as mutual knowledge transfer, and thus to speed up the development of the IBL technologies, major R&D efforts within TALENT are put into these industrial applications. The mutual R&D interests the intersectoral consortium partners share is likely to lead into particularly creative multidisciplinary learning environment within TALENT. The chosen training approach will deepen the existing R&D collaborations between the partners and, more importantly, give the participating young researchers expertise and understanding to build a successful international career in R&D in science, industry or in their interface.";4515563,06;4515563,06;FP7-PEOPLE-2011-ITN;/MC-ITN;EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH;CH;"CIS FORSCHUNGSINSTITUT FUR MIKROSENSORIK GMBH;UNIVERSITE DE GENEVE;FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.;ATOSTEK OY;RHEINISCHE FRIEDRICH-WILHELMS-UNIVERSITAT BONN;BERGISCHE UNIVERSITAET WUPPERTAL;UNIVERSITETET I OSLO;WIRTSCHAFTSUNIVERSITAT WIEN;STICHTING NEDERLANDSE WETENSCHAPPELIJK ONDERZOEK INSTITUTEN";"DE;CH;FI;NO;AT;NL";"/LIF;/SCI";1;0;0;1;0;0 96455;257453;COSYM;ONG;FP7-IDEAS-ERC;ERC-SG-PE6;FP7;Computational Symmetry for Geometric Data Analysis and Design;2011-02-01;2016-01-31;;"The analysis and synthesis of complex 3D geometric data sets is of crucial importance in many scientific disciplines (e.g. bio-medicine, material science, mechanical engineering, physics) and industrial applications (e.g. drug design, entertainment, architecture). We are currently witnessing a tremendous increase in the size and complexity of geometric data, largely fueled by significant advances in 3D acquisition and digital production technology. However, existing computational tools are often not suited to handle this complexity. The goal of this project is to explore a fundamentally different way of processing 3D geometry. We will investigate a new generalized model of geometric symmetry as a unifying concept for studying spatial organization in geometric data. This model allows exposing the inherent redundancies in digital 3D data and will enable truly scalable algorithms for analysis, processing, and design of large-scale geometric data sets. The proposed research will address a number of fundamental questions: What is the information content of 3D geometric models? How can we represent, store, and transmit geometric data most efficiently? Can we we use symmetry to repair deficiencies and reduce noise in acquired data? What is the role of symmetry in the design process and how can it be used to reduce complexity? I will investigate these questions with an integrated approach that combines thorough theoretical studies with practical solutions for real-world applications. The proposed research has a strong interdisciplinary component and will consider the same fundamental questions from different perspectives, closely interacting with scientists of various disciplines, as well artists, architects, and designers.";1160301,97;1160301,97;ERC-2010-StG_20091028;/ERC-SG;ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE;CH;;;"/PSE;/IPS";1;0;0;1;0;0 98650;273734;COREBRAS;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-IEF;FP7;COASTAL RESOURCES AND SOUTH AMERICAN HUNTER-GATHERERS: BIOCHEMICAL PERSPECTIVES FROM BRAZILIAN SAMBAQUIS;2011-10-01;2013-09-30;;'In the last decade there has been an explosion of interest into the role played by coastal ecosystems in the lives of hunter-gatherers. Studies have highlighted the importance of ecological, physical and climatic conditions of coastal areas on the biological evolution, dispersion, survival and social development of earliest humans. This new research direction offered more nuanced investigations: how important are coastal resources for humans with a shared cultural identity but living in different ecosystems? Do the social response to different coastal habitats changes over space and time? COREBRAS project aims to address these interrogatives to South America archaeology and specifically to Brazilian sambaquis. Sambaquis are cultural shell middens left by hunter-gatherer-fishers (HGF) that inhabited Brazilian coasts between ca. 8-1 ka BP. They represent the world’s largest evidence of prehistoric reliance on coastal resources. By undertaking these interrogatives, COREBRAS will provide new skills on human ecology and on the global role of coastal areas in the complex humankind’s adaptation to different environmental and climate conditions. COREBRAS will for the first time transfer scientific knowledge from European developments in biomolecular archaeology to Brazilian issues by mean of an extensive program of analysis on sambaquis (Human, fauna and artefact remains). With this aims I will exploit the remarkable concentration of expertise at the University of York (UK), the world’s leader in biomolecular archaeology. The proposed project represents a unique opportunity for cross-European integration of the study of one of the major forms of prehistoric site. The trained I will receive at the BioArCh group (University of York) in different biomolecular techniques will provide me multiple skills and competences to face objectives of COREBRAS project and enhance my interdisciplinary career opportunity within and outside the European scientific community.';200549,6;200549,6;FP7-PEOPLE-2010-IEF;/MC-IEF;UNIVERSITY OF YORK;UK;;;"/EMP;/EDU;/NET";1;0;0;1;0;0 93583;242993;GENESFORCEMOTION;ONG;FP7-IDEAS-ERC;ERC-SG-ID1;FP7;Physical Forces Driving Collective Cell Migration: from Genes to Mechanism;2010-01-01;2014-12-31;;Fundamental biological processes including morphogenesis, tissue repair, and tumour metastasis require collective cell motions, and to drive these motions cells exert traction forces on their surroundings. The mechanisms underlying this basic principle of health and disease have been debated intensively and, using a variety of methods in vivo, in vitro, and in silico, much conflicting evidence has accumulated. This conflicting evidence has been in every case indirect or inferential, however, because within the moving cell group the physical forces themselves have remained inaccessible to direct experimental observation. To fill this gap, this ERC application describes an interdisciplinary project to uncover the physical mechanisms underlying collective cell migration. In Objective 1, I propose to develop technology to map forces that cells within moving groups exert on each other and on their extracellular matrix. In Objective 2, we will use siRNA technology to provide a systematic analysis of the genes that regulate force generation and transmission in a migrating epithelial cell sheet. In Objective 3, we will use this pool of data to establish a constitutive link between genes, forces and collective cell motion. Although these Objectives present major technical and scientific challenges, the feasibility of each is supported by a unique technical know-how and by a productive track record in the field of cell biophysics.;1749745;1749745;ERC-2009-StG;/ERC-SG;FUNDACIO INSTITUT DE BIOENGINYERIA DE CATALUNYA;ES;UNIVERSITAT DE BARCELONA;ES;/SCI;1;0;0;1;0;0 92284;235167;CYRTANTHUS-DRUGS;ONG;FP7-PEOPLE;FP7-PEOPLE-IIF-2008;FP7;CYRTANTHUS-DRUGS: the predictive power of phylogenies in plant drug discovery - a case study of the genus Cyrtanthus (Amaryllidaceae);2010-08-01;2012-07-31;;This proposal, CYRTANTHUS-DRUGS, consists of a 24 months incoming phase to the Pharmacognosy Laboratory, Department of Medicinal Chemistry, University of Copenhagen, Denmark (host institution). CYRTANTHUS-DRUGS is very interdisciplinary and will use an array of molecular, chemical, biological, analytical and interview techniques, to produce a phylogeny of Cyrtanthus (Amaryllidaceae), as well as chemical profiles and central nervous system related biological activity profiles for at least 25 or half of the circa 50 species. The phylogeny and the chemical and activity profiles will then be used to evaluate the predictive power of a genus level phylogeny in plant drug discovery.;;204951,55;FP7-PEOPLE-IIF-2008;/MC-IIF;KOBENHAVNS UNIVERSITET;DK;;;"/SCI;/EMP";1;0;0;1;0;0 106374;302005;MUFO;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IEF;FP7;Multiscattering Formalism: Casimir Effect and Related Topics;2013-12-01;2015-11-30;;"CNRS is one of the most prestigious research institutions of Europe. Research work of this project will be carried out at the “Laboratoire de Physique Theorique et Modeles Statistiques” (LPTMS) in Orsay University. In the framework of this project, the fellow will get insight on one of the more fruitful and interesting developments on Casimir effect nowadays, the multiscattering formalism of Casimir effect. In this theoretical work, the fellow, under the supervision of one of the original developers of the multiscattering method, would extend the range of applicability of this method to new systems of theoretical and experimental interest. The project is divided in two parts, the first one is the study of Casimir effect in new geometries by the use of the multiscattering formalism: 1) Casimir effect between spheres and cylinders; 2) Effects of confinement in Casimir effect; 3) Implementation of a multiscattering based numerical method of Casimir effect. In the second part of the project, the goal is a generalization of the multiscattering formalism to study new systems that nowadays are beyond its range of applicability: 4) Interaction between arbitrary shaped charges and dielectrics; 5) The modification of the local density of states of the electromagnetic field because the presence of arbitrary shaped dielectrics in the system; 6) Study of dynamical situations, finite relative velocities and accelerations between bodies, and its connections with dynamical Casimir effect and Unruh effect. The level of interdisciplinarity of the proposed work is broad: dynamical and quantum-thermodynamical effects applied over systems of dielectrics and charges. We expect that the results of this project would be of interest in the community of Casimir effect and with experimental relevance.";193594,8;193594,8;FP7-PEOPLE-2011-IEF;/MC-IEF;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FR;;;/SCI;1;0;0;1;0;0 97378;264816;PHYPODE;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-ITN;FP7;Physiopathology of decompression : risk factors for the formation of intravascular bubbles during decompression;2011-01-01;2014-12-31;;"Decompression sickness (DCS) is caused by circulating inert gas bubble formation in blood vessels and tissues resulting from supersaturation during inadequate decompression. It is an acknowledged risk of situations involving variations in ambient pressure, such as space flight and extravehicular activity, exposure to altitude, hyperbaric tunnelling intervention, as well as recreational and commercial underwater diving. Because new industrial challenges (human space flight programs, deeper planed tunnelling interventions and offshore oil excavation) and emerging recreational demands, the range of both environmental conditions and population characteristics involved in such activities regularly widen. Thus, new interdisciplinary approaches of decompression are needed to reduce risk for DCS. To foster knowledge of decompression phenomena, the PHYPODE ITN proposes to : - Develop an educational and research framework for cross-fertilization of currently fragmented research activities on physiopathology of decompression; - Give young researchers opportunities to share research techniques and resources, benefit from the best international scientists knowledge in this field, have the advantages of strong interactions between industry, medical centres and academia; - Widen career prospectives of young researchers by embracing the whole chain of research : from fundamental research for pathophysiological understanding of decompression to applied research in the industry for management of decompression. To achieve this training programme, academic partners, non profit association with worldwide activities, hyperbaric medical centres and industrial partners, with complementary expertises will build up the common agreed program concerning education and research.";3397807,22;3397807,22;FP7-PEOPLE-2010-ITN;/MC-ITN;UNIVERSITE DE BRETAGNE OCCIDENTALE;FR;"G.T. DI TRAMPUS GRAZIELLA;RISE ACREO AB;IMEGO AB;SVEUCILISTE U SPLITU;GDANSKI UNIWERSYTET MEDYCZNY;HAUTE ECOLE PAUL-HENRI SPAAK;Minist?re de la Défense;DIVERS ALERT NETWORK EUROPE FOUNDATION;MARES SPA";"IT;SE;HR;PL;BE;MT";"/EDU;/NET";1;0;0;1;0;0 98562;273039;SymPati;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-IEF;FP7;Symbolic Pattern Recognition in Drug Design - Statistical Models and Scientific Insight;2011-10-01;2013-09-30;;Profound understanding of the relationship between molecular structure and biological activity is an essential prerequisite for rational drug design. Due to the inherent non-linearity of these relationships, ordinary regression is often inadequate, and black-box machine learning approaches offer limited, if any, interpretability. As a solution, we propose to use symbolic regression, in conjunction with a unique approach to feature selection, to establish quantitative structure-activity relationships (QSAR) that are succinct, non-linear, analytical, and interpretable. Symbolic regression is a stochastic optimization technique based on principles of evolution that searches the space of analytical expressions for equations that describe the investigated data. In other words, symbolic regression does not only fit the coefficients of an equation, but also the form of the equation itself. Our particular concept has not been used in QSAR before. We will combine theoretical investigations of the method with practical applications. Large combinatorial libraries will be analyzed to obtain validated QSAR models that are immediately and intuitively interpretable. Taking trypsin inhibition as an example, we will design, synthesize, and test new inhibitors suggested by our models. Our interdisciplinary project will contribute to European excellency in basic and applied pharmaceutical and medicinal chemistry, in line with health as a top priority of the seventh framework programme.;170401,6;170401,6;FP7-PEOPLE-2010-IEF;/MC-IEF;EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH;CH;;;"/EMP;/EDU;/NET";1;0;0;1;0;0 98479;274765;LACONIC;CAN;FP7-PEOPLE;FP7-PEOPLE-2010-IEF;FP7;LAttice COdiNg for multiuser wIreless Communications;2011-10-05;2013-10-04;;"'In the last decade, the wireless industry has witnessed an impressive growth worldwide. Advances in wireless technology have enabled a wide range of applications, from third generation (3G) mobile phones to new local area network and broadband standards such as WiFi and WiMAX. The demand for high-speed mobile capability continues to increase, with new standards being developed such as LTE and 4G. New communication paradigms are being introduced to exploit the capacity of wireless systems. Due to the shortage of licensed spectrum, multiuser systems are emerging as an alternative to time-sharing, enabling terminals to share bandwidth. The LACONIC project, to be carried out at Imperial College London by Dr Laura Luzzi (fellow) and Dr Cong Ling (host), aims at designing high-performance codes for the multiuser case, by addressing LAttice COdiNg for multiuser wIreless Communications. It is inspired by the recent breakthrough in network information theory, which has shown the significant theoretical potential of lattice codes. The project will realize this potential by constructing explicit multiuser lattice codes. It will focus on two main scenarios: the multiple access channel and the interference channel. A great challenge for the practical implementation of lattice codes is the complexity of decoders, which entails a prohibitive computational load for mobile devices. The project will develop low-complexity decoding algorithms which exploit the algebraic properties of the codes. Mathematical tools play a prominent role in the design of high-performance codes. Thus, the LACONIC project will benefit from an interdisciplinary study of recent techniques in the fields of number theory and cryptography. The proposed fellowship will enable Dr. Luzzi to widen the scope of her research from point-to-point communications to network coding, and to acquire an expertise in lattice coding. Training in hardware implementation will complement her theoretical background.'";192349,6;192349,6;FP7-PEOPLE-2010-IEF;/MC-IEF;IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE;UK;;;"/EMP;/EDU;/NET";1;0;0;1;0;0 104276;282693;ORION;ONG;FP7-SME;SME-2011-2;FP7;ORganic waste management by a small-scale Innovative automated system of anaerobic digestION;2012-08-01;2015-07-31;http://www.project-orion.eu/;"Restaurants, hotels, markets, fisheries and other small to medium size agro-food industries have to manage 239 million tonnes of organic waste in Europe per year. The specific management of such waste, with respect to the legislative regulations of EU, involves costly treatment for SMEs and potential hygiene issues on site. ORION aims at allowing a vast majority of SMEs to manage their organic waste by themselves in order to decrease their treatment costs (storage, transport, landfill or incineration) and increase on-site hygiene conditions. Wastes will be also valorised as biomass to produce energy and increase SME autonomy and profitability. ORION main objectives consist of: ? Developing for the first time anaerobic digestion machine at the SME scale (1 m3 to 50 m3) that will combine effectiveness for a large range of organic wastes and reduced capital and operating costs. ? Developing advanced control tools and sensors to reach an optimum reliability ? Increasing know-how on the impact of nanostructured surfaces on bacterial growth and increase waste throughput in the digestor ? Developing a dissemination and training strategy in order to address a vast community of SMEs and offer them a personalized service ? Contributing to the implementation of EU policies on waste management and renewable energies production. A maximum autonomy, adaptability and reliability are targeted. The digester is expected to be very cost-effective for users. ORION partnership is composed of European and National IAG representing the targeted sectors: fishery/aquaculture, hotel-restaurants, small agro-food industries and a Core Group of representative SME partners involved in the pilot design ND testing with various waste qualities and quantities. They will rely on a interdisciplinary group of research centers in order to achieve the technical goals of the project.";3880500,55;2978002,49;FP7-SME-2011;/BSG-SME-AG;DAITHI O'MURCHU MARINE RESEARCH STATION LTD;IE;"ASSOCIATION NATIONALE DES INDUSTRIES ALIMENTAIRES;VALIDEX SARL;INTERNATIONAL FEDERATION OF GREEN REGION ASSOCIATIONS;CSEM CENTRE SUISSE D'ELECTRONIQUE ET DE MICROTECHNIQUE SA - RECHERCHE ET DEVELOPPEMENT;THE UNIVERSITY OF MANCHESTER;UNIVERSITY OF SOUTH WALES PRIFYSGOLDE CYMRU;FASTNET MUSSELS LTD;OILEAN MARA TEORANTA;ADS SUSTAINABLE DEVELOPMENT CONSULTING SL;EUREXCEL MEMBERSHIP PROJECTS LIMITED;EUROPEAN BIOMASS INDUSTRY ASSOCIATION;DIGESTO SARL;MAISONNEUVE SAS;INSTITUT DE RECERCA I TECNOLOGIA AGROALIMENTARIES;HELVACIZADE GIDA VE IHTIYAC MADDELERI SANAYI VE TICARET AS;CAND-LANDI SA;ETA - ENERGIA, TRASPORTI, AGRICOLTURA SRL;HAUTE ECOLE SPECIALISEE DE SUISSE OCCIDENTALE;MURPHY'S IRISH SEAFOOD LIMITED;TUERKIYE SUET ET GIDA SANAYICILERI VE UERETICILERI BIRLIGI DERNEGI";"FR;CH;UK;IE;ES;BE;TR;IT";/SCI;1;0;0;1;0;0 109059;609942;MAREXPRES;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-NIGHT;FP7;Marine Exploring Researchers;2013-05-01;2013-11-30;;"'The National and Kapodistrian University of Athens in collaboration with the Hellenic Oceanographers’ Association aim to undertake ‘Marine Exploring Researchers’ (MAREXPRES) on Friday 27th September 2013, in the framework of ‘Researchers’ Night 2013’, under the scope to enhance public recognition of researchers across Europe. Therefore, the consortium intends to hold an outdoor event in The Old University in Plaka, one of the most attractive locations of Athens. MAREXPRES will try to communicate to the general public that researchers are ordinary individuals capable of socially interacting, whose profession is both challenging and fascinating. During the event the researchers will present some of the broad applications of Marine Sciences and their research trying to highlight that ocean exploration is useful to the society and improves our life. There will be an interdisciplinary approach by biologists, chemists, geologists and physicists, members of UOA laboratories and HOA, in a comprehensible yet scientific and festive way, with researchers acting as guides, animators, and coordinators. MAREXPRES will try to achieve a mass participation, addressing an audience of mixed age categories and backgrounds, giving the public the opportunity to frequent scientists in diverse circumstances, different from those usually anticipated. In addition, MAREXPRES will point out that European citizens can be EU support beneficiaries, such as of Marie Curie actions. The activities of the event, which will be of both scientific and entertaining nature and try to satisfy a broad spectrum of interests, will be planned and implemented by researchers of all levels. All the presentations, simulations and activities will expose attendees to ocean exploration and will try to set them in the shoes of researchers. Therefore, the MAREXPRES project aspires to constitute a central massive event.'";35887,2;31999,42;FP7-PEOPLE-2013-NIGHT;/CSA-SA;ETHNIKO KAI KAPODISTRIAKO PANEPISTIMIO ATHINON;EL;HELLENIC OCEANOGRAPHERS ASSOCIATION;EL;/LIF;1;0;0;1;0;0 93118;248346;NMSSBLS;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-RG;FP7;Nonlinear Mechanisms of Spatial Symmetry Breaking in Living Systems;2009-10-01;2013-09-30;;The study of experimental pattern formation mechanisms and its relevance to biology has been restricted to nonlinear chemical systems that produce spatial Turing patterns (CDIMA reaction), spiral waves (BZ reaction), propagating fronts and pulses (GO reaction). The important differences between these artificial systems and the natural spatial differentiation occurring in living cells do not allow for direct application of nonlinear dynamics tools to analyze biological patterns. The complexity of living organisms is also complicating the understanding of the underlying mechanisms for the arising of living patterns, therefore a much simpler symmetry breaking mechanism in living cells will allow a closer connection between developmental biologists and nonlinear physicists. The implementation of a spontaneous symmetry breaking mechanism in tissue culture mammalian cells using engineered cell-to-cell communication will constitute a highly improved model system for morphogenesis, early embryo development and skin patterning. This mechanism will be implemented using a highly interdisciplinary approach combining experimental /theoretical experience in chemical symmetry breaking systems and nonlinear physics tools together with a background in synthetic biology and signaling pathways. The candidate background in pattern formation, biophysics and cell biology combined with the expertise of the host laboratory (Elisa Martí at the Parc Cientific of Barcelona University) in symmetry breaking during early development constitute the perfect complement to carry out this type of research. An in-vitro pattern formation system will change the way biologists and physicists interact to understand the complexity of self-organization in living organisms.;100000;100000;FP7-PEOPLE-2009-RG;/MC-IRG;AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS;ES;;;/SCI;1;0;0;1;0;0 105611;307496;icyMARS;ONG;FP7-IDEAS-ERC;ERC-SG-PE9;FP7;Cold and wet early Mars: Proposing and testing a new theory to understand the early Martian environments;2014-01-01;2018-12-31;;Geologic evidence indicative of flowing and ponding liquid water on the surface of ancient Mars appears abundantly across most of the Martian landscape, indicating that liquid water was present in variable amounts and for long periods of time on and/or near the surface at different moments of Mars’ early history, the Noachian era. Early Mars appears to have been “wet”. However, the presence of liquid water on the surface of early Mars is difficult to reconcile with the reduced solar luminosity at 3.8 Ga. and before, which would have imposed mean temperatures below freezing all over the planet. Atmospheric greenhouse gases and carbon dioxide ice clouds in the upper troposphere are suggested to provide over freezing temperatures, explaining some of this discrepancy, but these solutions have been probed to face numerous problems. So, it is difficult to explain the early Martian hydrology invoking global “warm” conditions. Here I propose to conduct interdisciplinary investigations in order to define and test a new hypothesis to understand the early environmental traits on Mars: that the young Martian surface was characterized by global mean freezing conditions, as predicted by climate models, and at the same time a vigorous hydrogeological cycle was active during hundreds of millions of years, as confirmed by geomorphological and mineralogical analyses. The aim of this investigation is to comprehensively analyze the triggers, traits and consequences of a cold aqueous environment dominating the Noachian, studying the geomorphological, mineralogical and geochemical evidences that such a hydrological cycle would have left behind, and also proposing new paths for the astrobiological exploration of Mars on the basis of geochemical and geomicrobiological studies in cold aqueous environments. Mission-derived datasets will be used to test hypotheses through paleogeomorphological reconstructions, theoretical modeling and experiments in the laboratory.;1411200;1411200;ERC-2012-StG_20111012;/ERC-SG;AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS;ES;UNIVERSIDAD AUTONOMA DE MADRID;ES;"/PSE;/AER;/SPA";1;0;0;1;0;0 106594;310420;HYPERCONNECT;ONG;FP7-NMP;NMP.2012.2.1-1;FP7;Functional joining of dissimilar materials using directed self-assembly of nanoparticles by capillary-bridging;2013-01-01;2015-12-31;http://www.hyperconnect.eu/;"Tomorrows micro-electronic devices will have to show more functionality and performance at smaller form factor, lower cost and lower energy consumption in order to be competitive on this multi-billion dollar market. Advanced system integration is thus inevitable, a trend bound to joining dissimilar materials with new packaging technologies. These processes must enable lower thermal resistances and higher interconnect density and device reliability under thermomechanical loading. Hyperconnect addresses these challenges by a radically new material joining process. The objective is to demonstrate superior electrical, thermal and thermomechanical performance and to combine design and technology with the support of simulation and testing. The central new idea comprises a sequential joint forming process, using self-assembly of nanoparticles, polymers and filler composite materials exploiting capillary action and chemical surface functionalisation: In other words, the formed joint reaches its outstanding properties by the very processing of the materials. This contrast to existing technology demands own understanding of the joint formation, joint property creation and the joint reliability. Therefore advanced experimental characterization and simulation techniques will accompany the material and technology development, in particular involving physics-of-failure-based lifetime modelling. Finally, the joint performance will be validated on four different demonstrators of industrial significance. To tackle these challenging issues the consortium pools the required interdisciplinary excellence, by uniting nine partners from industry, SMEs and academia of five European countries. Its members are convinced that these new developments will outperform commercially available solutions by one order of magnitude and will radiate out also to other fields in electronic packaging.";4561845,8;3166808;FP7-NMP-2012-SMALL-6;/CP-FP;IBM RESEARCH GMBH;CH;"AMIC ANGEWANDTE MICRO-MESSTECHNIK GMBH;INTRINSIQ MATERIALS LIMITED;STIFTELSEN SINTEF;FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.;LORD GERMANY GMBH;STIFTINGA VESTLANDSFORSKING;CONPART AS;TECHNISCHE UNIVERSITAET CHEMNITZ;INSTYTUT KATALIZY I FIZYKOCHEMII POWIERZCHNI, POLSKA AKADEMIA NAUK";"DE;UK;NO;PL";/SCI;1;0;0;1;0;0 96653;257096;CAT4ENSUS;ONG;FP7-IDEAS-ERC;ERC-SG-PE5;FP7;Molecular Catalysts Made of Earth-Abundant Elements for Energy and Sustainability;2011-01-01;2015-12-31;;"Energy and sustainability are among the biggest challenges humanity faces this century. Catalysis is an indispensable component for many potential solutions, and fundamental research in catalysis is as urgent as ever. Here, we propose to build up an interdisciplinary research program in molecular catalysis to address the challenges of energy and sustainability. There are two specific aims: (I) bio-inspired sulfur-rich metal complexes as efficient and practical electrocatalysts for hydrogen production and CO2 reduction; (II) well-defined Fe complexes of chelating pincer ligands for chemo- and stereoselective organic synthesis. An important feature of the proposed catalysts is that they are made of earth-abundant and readily available elements such as Fe, Co, Ni, S, N, etc. Design and synthesis of catalysts are the starting point and a key aspect of this project. A major inspiration comes from nature, where metallo-enzymes use readily available metals for fuel production and challenging reactions. Our accumulated knowledge and experience in spectroscopy, electrochemistry, reaction chemistry, mechanism, and catalysis will enable us to thoroughly study the synthetic catalysts and their applications towards the research targets. Furthermore, we will explore research territories such as electrode modification and fabrication, catalyst immobilization and attachment, and asymmetric catalysis. The proposed research should not only result in new insights and knowledge in catalysis that are relevant to energy and sustainability, but also produce functional, scalable, and economically feasible catalysts for fuel production and organic synthesis. The program can contribute to excellence in European research.";1475712;1475712;ERC-2010-StG_20091028;/ERC-SG;ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE;CH;;;"/PSE;/IPS;/TEL";1;0;0;1;0;0 111079;612642;GHG-LAKE;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IRSES;FP7;Towards a comprehensive understanding of transport of energy and greenhouse gases in lacustrine ecosystems;2013-12-01;2016-11-30;;"The main objective of GHG-LAKE joint research programme is to increase mobility and exchange of researchers between EU countries, Russia and US to obtain better understanding of energy and greenhouse gases (methane and carbon dioxide) budgets in lake ecosystems at high-latitude, which are potentially most prone to on-going and future climate changes. Factors controlling the carbon cycles are investigated by means of intensive field measurements and process based modelling. This program focuses on four research aspects: 1) gas exchange processes; 2) carbon cycle, including greenhouse gases (GHG) flux database development for lacustrine ecosystems; 3) energy and greenhouse gas flux measurements, including research and knowledge transfer of key methodological aspects for comprehensive measurement sites; 4) process based biogeochemical modelling for GHGs production and transport in water bodies, as well as state of art large eddy simulation modelling for resolving non-homogeneous and non-stationary atmospheric boundary layer flow over heterogeneous surfaces (e.g. small lake surrounded by forest). GHG-LAKE programme builds a basis for long-term collaboration between the leading EU, Russian and US research organizations in the area of limnology, GHGs monitoring and modelling and climate change research in order to achieve new scientific results and breakthroughs. The proposed programme is interdisciplinary and the expected results will touch in particular the environmental sciences, limnology, biogeochemistry and micrometeorology research communities. GHG-LAKE will exploit complementary expertise of the participant organizations in order to create synergies among participants and to establish long-lasting partnership. As multi- and cross-disciplinary studies essential in climate change research are lacking in Russia, this programme will essentially also work towards an integrated approach for future joint international projects.";175600;175600;FP7-PEOPLE-2013-IRSES;/MC-IRSES;HELSINGIN YLIOPISTO;FI;"LINKOPINGS UNIVERSITET;STOCKHOLMS UNIVERSITET";SE;/LIF;1;0;0;1;0;0 101993;278855;HyTime;ONG;FP7-JTI;SP1-JTI-FCH.2010.2.4;FP7;Low temperature hydrogen production from second generation biomass;2012-01-01;2015-06-30;;"The aim of HyTime is to deliver a bioprocess for decentral H2 production from 2nd generation biomass with a productivity of 1-10 kg H2/d. The novel strategy in HyTime is to employ thermophilic bacteria which have shown superior yields in H2 production from biomass in the previous FP6 IP HYVOLUTION. Biomass in HyTime is grass, straw, molasses or unsold organic goods from supermarkets. The biomass is fractionated and converted to H2 at high efficiency unique for thermophilic fermentation. Dedicated bioreactors and gas upgrading devices for biosystems will be constructed to increase productivity. The H2 production unit will be independent of external energy supply by applying anaerobic digestion to valorize residues. HyTime adds to the security of supply H2 from local sources and eradicates geopolitical dependence. HyTime builds on HYVOLUTION with 5 partners expanding their research efforts. Three new industrial partners, 2 of which are NEW-IG members, have joined this team with specialist expertise in 2nd generation biomass fractionation and gastechnology. This way a pan-european critical mass in agro- and biotechnological research, the energy and hydrogen sector is assembled to enforce a breakthrough in bioH2 production. The participation of prominent specialists with interdisciplinary competences from academia (1 research institute and 2 universities) and industries (3 SMEs and 2 industries) warrants high scientific quality and rapid commercialization by exploitation of project results and reinforces the European Research Area in sustainable issues. The partners in HyTime have a complementary value in being developers or stake-holders for new market outlets or starting specialist enterprises stimulating new agro-industrial activities to boost the realization of H2 from renewable resources. The concept of HyTime will facilitate the transition to a hydrogen economy by increasing public awareness of the benefits of a clean and renewable energy carrier.";3057249,8;1606900;FCH-JU-2010-1;/JTI-CP-FCH;STICHTING WAGENINGEN RESEARCH;NL;"TECHNISCHE UNIVERSITAET WIEN;RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN;HEIJMANS TECHNIEK & MOBILITEIT B.V.;HYGEAR BV;VEOLIA ENVIRONNEMENT RECHERCHE ET INNOVATION SNC;AWITE BIOENERGIE GMBH;PARCO SCIENTIFICO E TECNOLOGICO PER L'AMBIENTE - ENVIRONMENT PARK SPA;WIEDEMANN-POLSKA PROJEKT SPOLKA Z OGRANICZONA ODPOWIEDZIALNOSCIA";"AT;DE;NL;FR;IT;PL";/IND;1;0;0;1;0;0 94709;250047;GABACELLSANDMEMORY;ONG;FP7-IDEAS-ERC;ERC-AG-LS5;FP7;Linking GABAergic neurones to hippocampal-entorhinal system functions;2010-07-01;2015-06-30;;GABAergic interneurones can effectively synchronize the activity of principal cells giving rise to distinct oscillatory patterns. A particular rhythm, hippocampal theta oscillations (6-10Hz), links two ways of coding by which pyramidal cells in the hippocampus represent space, namely rate and phase coding. Thus, the theta cycle provides a clock against which the increased firing rate of pyramidal cells in the hippocampus and entorhinal cortex is measured. Furthermore, hippocampal theta is believed to constitute a link to episodic memory. Recent evidence from our lab indicates that recruitment of GABAergic interneurones critically affects certain aspects of hippocampus-dependent spatial memory in mice. We have established genetic tools that allow us to manipulate GABAergic interneurones in a cell type and region-specific manner. In combination with in vivo electrophysiology in the hippocampus/entorhinal cortex and behavioural studies, we will investigate how GABAergic interneurones regulate the activity in neuronal networks and contribute to behaviour. Specifically, we will address the following questions: 1) How does reduced recruitment of GABAergic interneurones affect network activity (theta oscillations)? 2) How does altered activity of GABAergic interneurones affect spatial representation (activity of place cells in the hippocampus and grid cells in the entorhinal cortex)? 3) How does modified activity in the hippocampus affect activity in the entorhinal cortex (and vice versa)? 4) How does modified network activity and spatial representation translate into spatial memory? The interdisciplinary approach will enable us to provide better insight into how cellular activity of GABAergic interneurones relates to network activity and ultimately to behaviour.;1872000;1872000;ERC-2009-AdG;/ERC-AG;UNIVERSITAETSKLINIKUM HEIDELBERG;DE;;;"/BIO;/LIF";1;0;0;1;0;0 108418;334417;A3;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-CIG;FP7;Algebraic Algorithms and Applications;2013-05-01;2017-04-30;;"'The project Algebraic Algorithms and Applications (A3) is an interdisciplinary and multidisciplinary project, with strong international synergy. It consists of four work packages The first (Algebraic Algorithms) focuses on fundamental problems of computational (real) algebraic geometry: effective zero bounds, that is estimations for the minimum distance of the roots of a polynomial system from zero, algorithms for solving polynomials and polynomial systems, derivation of non-asymptotic bounds for basic algorithms of real algebraic geometry and application of polynomial system solving techniques in optimization. We propose a novel approach that exploits structure and symmetry, combinatorial properties of high dimensional polytopes and tools from mathematical physics. Despite the great potential of the modern tools from algebraic algorithms, their use requires a combined effort to transfer this technology to specific problems. In the second package (Stochastic Games) we aim to derive optimal algorithms for computing the values of stochastic games, using techniques from real algebraic geometry, and to introduce a whole new arsenal of algebraic tools to computational game theory. The third work package (Non-linear Computational Geometry), we focus on exact computations with implicitly defined plane and space curves. These are challenging problems that commonly arise in geometric modeling and computer aided design, but they also have applications in polynomial optimization. The final work package (Efficient Implementations) describes our plans for complete, robust and efficient implementations of algebraic algorithms.'";100000;100000;FP7-PEOPLE-2012-CIG;/MC-CIG;INSTITUT NATIONAL DE RECHERCHE ENINFORMATIQUE ET AUTOMATIQUE;FR;;;/LIF;1;0;0;1;0;0 107409;328794;PHOTOCAP;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IOF;FP7;Preparation and characterization of photo-responsive microcapsules based on azobenzene derivatives, for controlled delivery of active agents under visible light;2013-10-01;2016-09-30;;Encapsulation process is described as the capture of a compound into a coating material. Besides encapsulation technology is currently the best solution available on the market for the delivery of dedicated components/materials in different applications such as: food ingredients, perfumes, drugs, dyes, acids, pesticides and herbicides, etc. The main strategic objective of PhotoCap is to create an innovative platform for interdisciplinary research with the aim to accelerate the adoption of microcapsules-innovative solutions with significant contribution to European excellence. The research objective of the PhotoCap project focuses on development and testing of new photo-control release microcapsules for innovative breakthrough applications with high impacts on: environmentally-friendly production methods, health protection and increase of citizen daily life standard, with decreasing its cost. The novelty of this project will be preparation of new smart microcapsules based on azobenzen derivatives monomers containing electron-donating groups ortho to the azo moiety. It means that the controlled release of the encapsulated active agent will occur by visible light irradiation from sun illumination. During the PhotoCap I wish to develop and explore encapsulation and triggered release using as a model non-toxic substances such as perfumes under mild, consumer-relevant irradiation conditions. I wish to explore the incorporation of photo-responsive trigger materials into different encapsulation wall chemistry (e.g., polyamide, melamine formaldehyde), and seek to understand the stability and release behavior under different conditions of irradiation. During reintegration phase I wish to apply these new smart microcapsules to real products from EU market, check their stability in these products and disseminate the results in ERA in order to increase its attractiveness.;254925,9;254925,9;FP7-PEOPLE-2012-IOF;/MC-IOF;UNIVERSITAT ROVIRA I VIRGILI;ES;;;/LIF;1;0;0;1;0;0 96934;265137;CLUVA;ONG;FP7-ENVIRONMENT;ENV.2010.2.1.5-1;FP7;CLimate change and Urban Vulnerability in Africa;2010-12-01;2013-11-30;;The social and economic impact of natural disasters in emerging economies and developing countries is growing. Many African countries have fragile economies unable to absorb the shocks caused by natural disasters enhanced by the increasing vulnerability of rapidly expanding urban areas. Climate change is likely to rapidly exacerbate this situation. The overall objective of CLUVA is to develop methods and knowledge to be applied to African cities to manage climate risks, to reduce vulnerabilities and to improve coping capacity and resilience towards climate changes. CLUVA will explore these issues in selected African cities (Addis Ababa, Dar es Salaam, Douala, Ougadougou, St.Louis). The project aims at improving the capacity of scientific institutions, local councils and civil society to cope with climate change. CLUVA will assess the environmental, social and economic impacts and the risks of climate change induced hazards expected to affect urban areas (floods, sea-level rise, storm surges, droughts, heat waves, desertification, storms and fires) at various time frames. The project will develop innovative climate change risk adaptation strategies based on strong interdisciplinary components. CLUVA will be conducted by a balanced partnership of European and African partners. The 7 European partners will bring together some of EU’s leading experts in climate, quantitative hazard and risk assessment, risk management, urban planners and social scientists. The 6 African partners from South Africa and from the Universities of the selected cities cover a similar range of expertises, making possible an effective integrated research effort. The project is structured in 6 WorkPackages dealing with climate change and impact models (WP1), multiple vulnerability (WP2), urban planning and governance as key issues to increase the resilience (WP3), capacity building and dissemination (WP4), coordination of the activities in the selected cities (WP5) and project management (WP6).;4397825;3494580,75;FP7-ENV-2010;/CP-FP-SICA;AMRA - ANALISI E MONITORAGGIO DEL RISCHIO AMBIENTALE SCARL;IT;"ADDIS ABABA UNIVERSITY;UNIVERSITE DE YAOUNDE I;THE UNIVERSITY OF MANCHESTER;TECHNISCHE UNIVERSITAET MUENCHEN;HELMHOLTZ-ZENTRUM FUER UMWELTFORSCHUNG GMBH - UFZ;KOBENHAVNS UNIVERSITET;NORSK INSTITUTT FOR BY- OG REGIONFORSKNING;COUNCIL FOR SCIENTIFIC AND INDUSTRIAL RESEARCH;UNIVERSITE DE OUAGADOUGOU;ARDHI UNIVERSITY;FONDAZIONE CENTRO EURO-MEDITERRANEO SUI CAMBIAMENTI CLIMATICI;UNIVERSITE GASTON BERGER DE SAINT LOUIS";"ET;CM;UK;DE;DK;NO;ZA;BF;TZ;IT;SN";"/REG;/ENV";1;0;0;1;0;0 108374;328563;BVPsymmetry;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IIF;FP7;Reductions and exact solutions of boundary value problems with moving boundaries by means of symmetry based methods;2013-09-23;2015-06-22;;"Boundary value problems with moving boundaries are widely used in mathematical modeling a huge number of processes, which arise in physics, biology and industry. While these processes can be very different from a formal point of view, they have the common peculiarity: unknown moving boundaries. The most important subclass of such boundary value problems (BVPs) is the Stefan problems, in which the movement of unknown boundaries is governed by the well-known Stefan boundary conditions. BVPs with moving boundaries, particularly the multidimensional Stefan problems, are the main object of the proposed project. Developing new theoretical foundations and algorithms for reduction of such BVPs to those of lower dimensionality and construction of exact solutions of BVPs in question is the main aim of the project. Applied goal is to compare the analytical results derived with those obtained by means of the appropriate numerical techniques in the case of a wide range of the physically and biologically motivated problems. Moreover such comparison will demonstrate the real interdisciplinary aspect of the proposal. The novel idea of the project is to develop the algorithms mentioned above using such symmetry based methods as the classical Lie-Ovsiannikov method, the Bluman-Cole method of non-classical symmetry, conditional symmetry method and their recent extensions. The main results to be achieved: new definitions of (generalized) conditional invariance for BVPs with a wide range of boundary conditions will be derived; algorithms for how to construct all possible conditional symmetries for the given class of BVPs will be determined; new analytical results (conditional symmetries, reductions and exact solutions of BVPs) will be established by application of the algorithm to a wide range of nonlinear BVPs modeling the tumour growth processes and melting-evaporation processes.";270580,8;270580,8;FP7-PEOPLE-2012-IIF;/MC-IIF;THE UNIVERSITY OF NOTTINGHAM;UK;;;/SCI;1;0;0;1;0;0 97771;253633;THE CULT OF HERITAGE;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IOF;FP7;Dreamings, Songlines and the “Cult of Heritage”: Tourism Development and Aboriginal Culture in Broome, Western Australia;2011-10-01;2014-09-30;;This project analyses tourism development in relation to social policy in Broome, Western Australia. Tourism is the largest and fastest growing industry in the world and therefore a major field in the area of globalization. Social policy is an integral part of this growing market space. The central question is how images of Aboriginal culture and environment change through tourism impact and how these changes affect minorities and their political representation in Australian society. The primary research site is the town of Broome and the Lurujarri Heritage Trail in the Kimberley region of Western Australia. The trail follows an Aboriginal song cycle along the Indian Ocean coast. It originated from the Dreamtime Ancestral Beings who in Aboriginal culture are believed to have created the landscapes, humans, animals and plants, all of which are interconnected by the same life spirit. The landscape, its narrations and imaginaries are compared with what people on different ends – government officials, social and economic entrepreneurs, minority representatives, tourists – have to say about their rediscovery and development for the tourism industry. By taking a ‘grassroots’ perspective the focus of the project is on people as key players in the field of tourism and social policy. The research is grounded in a collaboration between the Social Policy Research Centre (SPRC) at the University of New South Wales (UNSW), Australia and the Institute of Social Anthropology and Philosophy (ISAP) at Martin-Luther-University Halle-Wittenberg (MLU), Germany. It is an integral part of initiatives to form an interdisciplinary research hub on Tourism, Globalization and Ethnicity at MLU in close collaboration with major research centres in the field, inside and outside of Europe. This research hub will link questions of cultural contact and knowledge production in tourism contexts with state of the art scientific discourse on sustainability, ‘environmental capital’ and heritage.;251603,3;251603,3;FP7-PEOPLE-2009-IOF;/MC-IOF;MARTIN-LUTHER-UNIVERSITAET HALLE-WITTENBERG;DE;;;"/LIF;/EDU";1;0;0;1;0;0 105583;316494;Destiny;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-ITN;FP7;DyE SensiTized solar cells wIth eNhanced stabilitY;2012-11-01;2016-10-31;;The DESTINY initial training network will tackle major challenges in the development of stable dye-sensitized solar cells, DSC. DSC offer exciting possibilities for applications in building integrated photovoltaics and consumer electronics. However they possess a complex structure with disparate materials. For DSC to be marketable and to compete with its inorganic counterparts, fundamental science has to be done to understand the causes of degradation and find ways of enhancing cell and module life time and stability without sacrificing performance and scalability. Ten internationally leading European research groups from six countries [including Dyesol UK, part of Europe’s leading industrial supplier of DSC] have joined forces as full participants with a commercial associated partner, combining expertise in synthetic chemistry, spectroscopy, nanoscale physics and device engineering. Our highly integrated approach to understanding degradation causes and proposing solutions will take a major step towards the commercialization of DSC. This consortium is strongly committed to promote breakthroughs at the frontiers of science and engineering. The training dimension of DESTINY is reflected in the high priority we give to the training of early stage and experienced researchers, ESRs and ERs, through education and knowledge dissemination via Tutorial Courses, Annual Network Meetings, Training Schools, Conferences and Mobility Programmes. The network, with a strong focus on interdisciplinary training, builds on fruitful collaborations between the partners. Development of complementary skills (presentation, management, technology transfer, IP protection) will take place throughout the project lifetime. Interaction with stakeholders beyond those involved primarily in research will be maintained to enhance the international and societal dimension of our research and provide the wider community with information on this new technology.;3848961,62;3848961,62;FP7-PEOPLE-2012-ITN;/MC-ITN;UNIVERSITY OF BATH;UK;"UNIVERSITA DEGLI STUDI DI ROMA TORVERGATA;UNIVERSITAT JAUME I DE CASTELLON;GREATCELL SOLAR UK LIMITED;FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA;BAR ILAN UNIVERSITY;OXFORD PHOTOVOLTAICS LIMITED;""NATIONAL CENTER FOR SCIENTIFIC RESEARCH """"DEMOKRITOS"""""";THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;3GSOLAR PHOTOVOLTAICS LTD";"IT;ES;UK;IL;EL";/LIF;1;0;0;1;0;0 93585;246637;OPTELOMAC;ONG;FP7-IDEAS-ERC;ERC-AG-PE5;FP7;Opto-Electronic Organic Materials by New Acetylene Chemistry;2010-03-01;2015-02-28;;"'Atom-economic, atom-economic ('click'-type)transformations of donor (N,N-dialkylaniline, TTF, ferrocene)-activated acetylenes with strong electron-accepting olefins (TCNE, TCNQ, tricyanovinyl derivatives) are applied to the construction of stable molecular and supramolecular chromophores with unusual electronic and optical properties. Their properties are characterized in interdisciplinary collaboration with the objectives to provide new classes of chromophores for opto-electronic device applications, to investigate pi-electron delocalization in acetylenic molecular architectures extending into one, two, and three dimensions, and to advance fundamental knowledge in an interplay between experiment and theory allowing prediction and tuning of opto-electronic properties. Specific aims are: 1. New "super-electron acceptors" and investigation of their intra- and intermolecular charge-transfer interactions. These non-planar, stable, and sublimable chromophores are expected to possess high third-order optical nonlinearities and are investigated for formation of amorphous, high-optical quality films and conductive or magnetic charge-transfer complexes and salts with various electron donors. 2. Optically pure alleno-acetylenic macrocycles and oligomers adopting helical conformations. The chiroptical properties of these chromophores are exceptional and will be further enhanced in supramolecular assemblies. 3. Covalently modified fullerenes with increased electron uptake capability for applications in photovoltaic devices. 4. Regular [AB]-type oligomers and polymers using the formation of charge-transfer chromophores from acetylenic precursors as the chain-propagation step. 5. Zwitterionic, redox-amphiphilic dendrimers for mono- and multi-layer formation in organic electronic devices.'";1690200;1690200;ERC-2009-AdG;/ERC-AG;EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH;CH;;;"/PSE;/MAT;/IND";1;0;0;1;0;0 111113;618537;WMCIG;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-CIG;FP7;Inter- and Intra-Individual Differences in Knowledge-Based Inference Generation During Reading Comprehension: The Role of Working Memory Capacity and Utilization;2013-12-01;2017-11-30;;'Reading comprehension is a high-order complex process that depends on the operation of various cognitive mechanisms. The present research aims to explore the interaction of three central mechanisms: knowledge-based inferences, working memory (WM), and motivation. Specifically, the proposed research was designed to study the involvement of the different functions of working memory—storage, processing, and control—in inference generation via different forms of text processing (text maintenance, text reactivation, and text suppression, respectively). A comprehensive interdisciplinary approach is adopted to explore the extent to which these comprehension processes underlie inter-individual and intra-individual differences. Specifically, by using cognitive-behavioral techniques (e.g., probing procedures), eye-tracking methodology, and computational modeling, I intend to study the extent that each of the target processes (a) explains different types of reading disabilities, (b) typically develops with age, and (c) is modulated by reading comprehension motivation. The theoretical contribution of the present investigations to the cognitive models of reading comprehension and the practical implications on the development of comprehension strategies and remedial programs are stressed throughout the proposal.';100000;100000;FP7-PEOPLE-2013-CIG;/MC-CIG;BAR ILAN UNIVERSITY;IL;;;/LIF;1;0;0;1;0;0 96882;264506;NANOTOES;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-ITN;FP7;Nanotechnology: Training Of Experts in Safety;2010-11-01;2015-02-28;;Life Sciences and Nano Sciences interact today mainly in two areas: in the evaluation of accidental health and environmental effects derived from engineered nanomaterials, and in development and biological/clinical evaluation of nanoparticles with intended biological effects for application in medicine and biotechnology. It is essential for producers, distributors, consumers and regulators that the safety of products containing nanomaterials can be certified with reliable, validated assays. Research efforts are under way to establish suitable test methods and to understand mechanisms potentially leading to a detrimental impact of nanomaterials on human health and on the environment. However, this important field still urgently lacks sufficient trained personnel. The ITN “Nanotechnology: Training Of Experts in Safety” (NanoTOES) will establish a network of research projects working towards the refinement and standardisation of existing methods, will develop novel assays, and will during this process provide interdisciplinary training to Early Stage Researchers (ESR) and Experienced Researchers (ER) working at the intersection of biosciences and nanosciences. A suite of methods developed and validated in the NanoTOES project shall have utility in characterising the biological effects of nanomaterials, including their impact on the environment, and will add significantly to our understanding of the biological actions of nanomaterials and their resultant effects on human health and the environment. Equally, the influence of biological entities (molecules, cells, tissues) on the properties of nanomaterials will be investigated. This aspect is crucial to understanding the properties of nanomaterials in organisms and in the environment, but nevertheless this issue has been so far not sufficiently explored. These timely and novel studies will address the pressing need for such trained personnel, and enable European science in this area to remain globally competitive.;3254330;3254330;FP7-PEOPLE-2010-ITN;/MC-ITN;PARIS-LODRON-UNIVERSITAT SALZBURG;AT;"UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN;FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.;BAYER TECHNOLOGY SERVICES GMBH;FUNDACIO INSTITUT CATALA DE NANOCIENCIA I NANOTECNOLOGIA;NORSK INSTITUTT FOR LUFTFORSKNING STIFTELSE;INSTITUT UNIVERSITAIRE ROMAND DE SANTE AU TRAVAIL;INSTITUTE OF EXPERIMENTAL MEDICINE - HUNGARIAN ACADEMY OF SCIENCES;CONSIGLIO NAZIONALE DELLE RICERCHE;AvantiCell Science Ltd;GRIMM AEROSOL TECHNIK Gmbh & Co KG;NATURAL ENVIRONMENT RESEARCH COUNCIL";"IE;DE;ES;NO;CH;HU;IT;UK";"/EDU;/NET";1;0;0;1;0;0 100878;274448;BFM;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-IOF;FP7;Brahms and the Fabric of Modernist Culture;2011-09-21;2014-09-20;;"'This large-scale project, to be carried out in the University of California, Irvine (outgoing phase) and University College Dublin (return phase) proposes to allow the expert researcher reach a level of professional maturity in the areas of research and teaching in the field of musicology, with a speciality in German music criticism and aesthetics of the late-nineteenth and twentieth centuries; the expert researcher aims to research and write a monograph in her field, to establish international collaborative relationships, to establish an international centre of excellence for music aesthetics–the first of its kind globally, and to secure a prominent lecturing post on her return to Europe. The research proposal, “Brahms and the Fabric of Modernist Culture” explores Modernism in relation to Brahms, and Brahms’s critics in relation to Modernism. It is an interdisciplinary project that focuses on the intersection between musicology, aesthetics, German studies, and philosophy. These Modernist critics, some of whom were born in the cultural atmosphere of the nineteenth century, and some of whose academic careers and writings were shaped by their twentieth-century critical, philosophical and academic milieu, include Hanslick, Nietzsche, Bloch, Schoenberg, and Adorno. This research will establish a model for uncovering how we shape perceptions of composers. It will explore the shaping of the subject that takes place while the composer is alive and for a period of approximately fifty years after their death. It will examine how the aesthetic persona is created, how linear chains of causal relationships are constructed in music criticism and music history, and assess the criteria by which a certain view of a composer obtains a dominant position. In its inter-disciplinary approach, this research, therefore, should provide a valuable model that can be applied to other composers.'";226024;226024;FP7-PEOPLE-2010-IOF;/MC-IOF;UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN;IE;;;"/EMP;/SOC;/COO";1;0;0;1;0;0 106796;307110;Calcyan;ONG;FP7-IDEAS-ERC;ERC-SG-PE10;FP7;A living carbonate factory: how do cyanobacteria make rocks? (Calcification in Cyanobacteria);2013-02-01;2018-01-31;;"This interdisciplinary proposal stems from our recent discovery of deep-branching cyanobacteria that form intracellular Ca-Mg-Sr-Ba carbonates. So far, calcification by cyanobacteria was considered as exclusively extracellular, hence dependent on external conditions. The existence of intracellularly calcifying cyanobacteria may thus deeply modify our view on the role of cyanobacteria in the formation of modern and past carbonate deposits and the degree of control they achieve on this geochemically significant process. Moreover, since these cyanobacteria concentrate selectively Sr and Ba over Ca, it suggests the existence of processes that can alter the message conveyed by proxies such as Sr/Ca ratios in carbonates, classically used for paleoenvironmental reconstruction. Finally, such a biomineralization process, if globally significant may impact our view of how an ecosystem responds to external CO2 changes in particular by affecting most likely a key parameter such as the balance between organic carbon fixed by photosynthesis and inorganic carbon fixed by CaCO3 precipitation. Here, I aim to bring a qualitative jump in the understanding of this process. The core of this project is to provide a detailed picture of intracellular calcification by cyanobacteria. This will be achieved by studying laboratory cultures of cyanobacteria, field samples of modern calcifying biofilms and ancient microbialites. Diverse tools from molecular biology, biochemistry, mineralogy and geochemistry will be used. Altogether these techniques will help unveiling the molecular and mineralogical mechanisms involved in cyanobacterial intracellular calcification, assessing the phylogenetic diversity of these cyanobacteria and the preservability of their traces in ancient rocks. My goal is to establish a unique expertise in the study of calcification by cyanobacteria, the scope of which can be developed and broadened in the future for the study of interactions between life and minerals.";1659478;1659478;ERC-2012-StG_20111012;/ERC-SG;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FR;;;"/PSE;/ENV;/EAR";1;0;0;1;0;0 88239;211166;MINATRAN;ONG;FP7-IDEAS-ERC;ERC-SG-PE6;FP7;Probing the Micro-Nano Transition: Theoretical and Experimental Foundations, Simulations and Applications;2008-10-01;2013-09-30;;The objective is to develop a robust multifunctional framework/probe for capturing the evolution of deformation and failure in a variety of processes at the micro-nano transition regime. An interdisciplinary approach will be pursued based on fundamental theory and experiment, in conjunction with multiscale simulations for micro/nanotechnology applications. The approach is unconventional as it ventures to extend continuum mechanics down to the micro/nano regime and verify this through nanoindentation and atomic force microscopy techniques. It is also unique as the new phenomenology introduced for establishing this extension (higher order gradients accounting for microscopic processes and interfacial energy terms accounting for nanoscopic phenomena) will be substantiated through hybrid (ab initio-atomistic-defect-finite element) simulations. The framework will be employed to consider fracture and size effects in a number of micro-nano scale transition configurations ranging from nanograined aggregates and nanolayered structures to nanotubes and micropillars, and from Li-ion battery electrodes to bioactive interfaces. Other micro/nano objects such as quantum dots, nanowires and NEMS/MEMS devices, as well as biomolecular microcrystalline membranes leading to living cell division will be considered. In a sense this “scale” transition theory is reminiscent in scope to Landau’s “phase” transition theory where a variety of different physical phenomena can be treated within a common framework. This optimism stems from the PI’s previous success with this approach, as well as Smalley’s remark that the “laws of continuum mechanics are amazingly robust for treating even intrinsically discrete objects only a few atoms in diameter”. A good mix of young researchers and mature scholars will be employed, thus connecting people and ideas through joint publications and scholarly activities in a critical area of fundamental and applied research.;1128400;1128400;ERC-2007-StG;/ERC-SG;ARISTOTELIO PANEPISTIMIO THESSALONIKIS;EL;"FRIEDRICH-ALEXANDER-UNIVERSITAET ERLANGEN NUERNBERG;FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS";"DE;EL";"/PSE;/IPS";1;0;0;1;0;0 102809;301056;URBAN RECOVERY 14-39;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IOF;FP7;Rebuilding European Lives. The reconstitution of urban communities in inter-war Europe (1914-1939);2013-01-01;2016-04-29;;"This project will investigate the reconstitution of urban communities in Europe in the aftermath of the First World War. It will thus produce an urban history of the transition from war to peace. Based on a longitudinal study of communities affected by military operations on the battlefields of France and Belgium, it will reveal some of the critical implications of the prosecution of “total war” in Europe. The research will investigate the resettlement of war veterans and refugees in the localities and regions laid to waste by the conflict. It will explore previously neglected aspects of the reconstruction to supplement conventional approaches to the post-war stabilization of Western Europe. A genuinely comparative and transnational project, it will build on recent studies of cultural and political demobilization after WWI to combine the history of “sorties de guerre” with a renewed approach to the reconstruction of formerly belligerent societies. This project will depart from traditionally state-centred accounts to combine local and transnational perspectives on the reconstruction and demobilization of belligerent societies. The project will also adopt an interdisciplinary approach and engage with a range of other social sciences including sociology and urban planning, archaeology, anthropology, as well as with specialists of conflict resolution and peace building. Looking forward to the Centenary of the outbreak of the First World War in 2014, the Fellow, with the support of the host institutions, will lay the foundation of a larger collaborative project which will cut across frontlines to investigate the recovery of urban communities along the Western and Eastern fronts. This project, as well as the outreach initiatives devised to disseminate its results, will therefore challenge national myths and historiographical exceptionalisms to integrate differentiated experiences through the systematic use of comparative and transnational frameworks of analysis.";371166,7;371166,7;FP7-PEOPLE-2011-IOF;/MC-IOF;THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN;IE;;;/SCI;1;0;0;1;0;0 108772;609775;Interfaces;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-NIGHT;FP7;Interfaces, The Art of Science;2013-05-01;2013-11-30;;"“INTERFACES, the Art of Science” will highlight Dusseldorf as a European capital of science, art and culture. INTERFACES symbolises the link between science and society, research and art, technology and design, tradition and vision. There is a high potential for innovation at the interface between science and art that is vital for the progress of science and society. INTERFACES will show that innovative solutions of current and future problems, such as demographic change, energy development or motivation of young people for a scientific career can only be found by understanding the interaction between science, society, culture and art. INTERFACES will show fascinating scientific results and developments created in cooperation between scientists from multiple disciplines, different faculties and universities in Dusseldorf. During INTERFACES, the city centre will be transformed into one enormous science laboratory highlighting the role of the researchers. The programme offers a colourful mix of experiments, presentations, interactive installations and games, panel discussions and performances and will attract a wide audience from all age groups. Several representative buildings and institutions will host scientific and artistic presentations, thus allowing visitors to experience research directly and in unusual venues not always accessible to the public. For the first time in Dusseldorf, Researchers’ Night will be organised by three public higher education institutes: The University of Applied Sciences (FHD), Heinrich Heine University (UDUS) and Robert Schuman School of Music and Media (RSH), supported by the Art Academy and the City of Dusseldorf. Thanks to the different but complementary nature of the partners, INTERFACES is interdisciplinary and brings together scientists from media technology to natural sciences, from medical sciences to art activities. INTERFACES will be the start of an annually ongoing event in the state capital of North Rhine-Westphalia.";367460;80000;FP7-PEOPLE-2013-NIGHT;/CSA-SA;HOCHSCHULE DUSSELDORF;DE;"HEINRICH-HEINE-UNIVERSITAET DUESSELDORF;ROBERT SCHUMANN HOCHSCHULE DUSSELDORF";DE;/LIF;1;0;0;1;0;0 87619;208948;NANOPOTS;ONG;FP7-IDEAS-ERC;ERC-SG-PE6;FP7;Nanotube Based Polymer Optoelectronics;2008-10-01;2013-09-30;;The target of this project is to develop a new class of polymer based optoelectronic devices embedding the optical and electronic functionalities of carbon nanotubes (CNTs). These devices will combine the fabrication advantages of polymer photonics, with the tunable active and passive optical properties of CNTs. This is an ambitious frontier research program, with a strong interdisciplinary nature, across engineering, physical, chemical and soft matter sciences. The ERC grant will consolidate the newly funded Research Group lead by the PI at the newly built centre for Advanced Photonics and Electronics of the University of Cambridge. CNTs will be grown by chemical vapour deposition at low temperatures, compatible with polymer processing. Direct deposition of CNT on optical components (such as fibres and mirrors) will be studied. Fundamental understanding of ultra-fast non-linear optics will be sought by a combination of theory and experiments. A range of novel photonic polymers incorporating CNTs will be produced: index matching gels, optical adhesives and silicones. These new materials, incorporating the optical functionality of CNTs, will be used to build a variety of photonic devices. Nanowires are also promising for photonic applications, since they exhibit a size-tunable absorption resonance at telecommunications wavelengths, and their use will also be considered.;1799964;1799964;ERC-2007-StG;/ERC-SG;THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;UK;;;"/PSE;/IPS";1;0;0;1;0;0 111150;340903;COOPETITION;ONG;FP7-IDEAS-ERC;ERC-AG-SH1;FP7;Cooperation and competition in vertical relations: the business strategies and industry oversight of supply agreements and buying patterns;2013-12-01;2018-11-30;;"'The application proposes to revisit the economics of cooperation and competition in industry vertical chains and develop new tools for industrial organization (IO). Modern IO theory treats firms as unitary, profit-maximizing entities, characterized by well-identified perimeters of activity, and clearly identified either as competitors or as complementors. Yet in practice: - Industry structures are increasingly complex: Firms distribute for example their activities among partners across the globe, and moved to multiple, interlocking relationships. - Firms competing for customers or suppliers are also cooperating in other dimensions, e.g., by setting-up common platforms, or by adopting joint common rules within which to compete. - Supplier -customer relations often involve transaction costs other than pure search costs: adoption costs, learning or shopping costs, or expensive strategies to protect sensitive information. Understanding the interplay between competition and cooperation is key to designing business strategies, but it has also implications for industry oversight: When should cooperation among competitors be limited or encouraged? Over which dimensions? This application proposes to cover three topics: 1. Allocation of tasks and the choice of partners. 2. Multilateral interlocking relations. 3. Cooperation and competition. 4. Transaction costs, buying patterns and business strategies While the project falls primarily in the field of applied theory, some of the developments require new tools and interaction with game theorists. Furthermore, empirical validation will require the use of structural econometric modelling (based in particular on consumer panel data) and laboratory experiments. The project has also an interdisciplinary flavour and will benefit from work of and interactions with legal scholars and marketing experts.'";2068920;2068920;ERC-2013-ADG;/ERC-AG;FONDATION JEAN-JACQUES LAFFONT,TOULOUSE SCIENCES ECONOMIQUES;FR;;;"/ECO;/SOC;/BUS";1;0;0;1;0;0 185456;603191;PAINCAGE;ONG;FP7-HEALTH;HEALTH.2013.2.2.1-5;FP7;The NGF system and its interplay with endocannabinoid signalling, from peripheral sensory terminals to the brain: new targets for the development of next generation drugs for neuropathic pain;2014-04-01;2017-12-31;http://www.paincage.eu/;"So far, there are no effective treatments for neuropathic pain (NP), and current treatments suffer from serious unwanted side effects. The NGF ligand-receptor system has recently emerged as a novel target for NP of great therapeutic potential, a master regulator, controlling both neuropathic and inflammatory components. Besides being a multi-component system, it also modulates the endocannabinoid (EC) signalling. Blocking the NGF signaling system is therefore a rational and thoroughly validated approach to pain therapy. Extensive evidence for potent analgesic efficacy of antiNGF mAbs has been obtained in preclinical models and in clinical trials,showing remarkable analgesic efficacy and creating great expectations for this new class of analgesic compounds.However, potential safety concerns related to off-target side effects have been raised and recently the FDA called for more preclinical research. To fully exploit the huge therapeutic potential of NGF system, we built a consortium of leading researchers in the NGF, EC and pain scientific arena.The innovative proposal will investigate new strategies for the treatment of different NP forms, based on the NGF system and its interplay with EC signalling, focussing at different levels of the pain transmission and perception systems. The project results will provide solid, mechanism-based grounds for the development of already identified second-generation therapeutics, based on the “NGF target” system, as well as for the identification and validation of new druggable targets emerging from the elucidated mechanisms. It will also identify biomarkers for NP, validated in animal models and clinical samples, that could result in future clinical benefits, for the stratification of patients suffering from different neuropathies and their treatment. The project will contribute to the understanding and controlling NP mechanisms, with an interdisciplinary approach, leading to the development of next-generation NGF targeting drugs.";7878342,13;5860831;FP7-HEALTH-2013-INNOVATION-1;/CP-FP;SCUOLA NORMALE SUPERIORE;IT;"MEDIZINISCHE UNIVERSITAET WIEN;AARHUS UNIVERSITET;INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE;LEVICEPT LTD;GENOMNIA SRL;FONDAZIONE EUROPEAN BRAIN RESEARCHINSTITUTE RITA LEVI;KING'S COLLEGE LONDON;UNIVERSIDAD DE SALAMANCA";"AT;DK;FR;UK;IT;ES";/LIF;1;0;0;1;0;0 98705;268646;TRACTAR;ONG;FP7-IDEAS-ERC;ERC-AG-LS9;FP7;Tracking and Targeting a T-DNA Vector for Precise Engineering of Plant Genomes;2011-05-01;2016-04-30;;DNA introduced into a cell usually integrates, if at all, at random in the genome. In order for gene targeting to take place, a small vector must scan a huge genome that is packaged in chromatin, identify and bind the target, and engage in strand exchange. This formidable task is likely to be rate limiting. Our goal is to study the process of genome scanning by the vector, to track it from the time of transformation through genome integration and to assist the vector to identify the homologous target. Our tools are particle imaging and tracking, molecular analysis of integration events, and manipulation of the integration process through protein recognition chemistry. Two main approaches will be used to assist homologous integration: first, by protein bridging (proteins that would bind both target and vector), and second by chromatin remodeling. Second, we propose to analyze the connection between chromatin structure and DNA integration. We will analyze how nucleosome positioning affects patterns of DNA integration. In addition, we will stimulate chromatin remodeling in an attempt to facilitate target invasion by the incoming vector. Parallel assays will be built upon fluorescence and genetic markers to correlate between the mode of search and integration per se. The interdisciplinary use of biophysics, genetics, and computational tools opens the prospect to better understand and manipulate the fundamental mechanisms involved in DNA mobility, plant transformation, and gene targeting.;1958408;1958408;ERC-2010-AdG_20100317;/ERC-AG;WEIZMANN INSTITUTE OF SCIENCE;IL;;;"/ABI;/BIO;/LIF;/MED;/MBI";1;0;0;1;0;0 97010;257670;COSMOIGM;ONG;FP7-IDEAS-ERC;ERC-SG-PE9;FP7;The Intergalactic Medium as a Cosmological Tool;2010-12-01;2016-11-30;;"The cosmoIGM proposal aims at investigating the role of the Intergalactic Medium (IGM) as a cosmological probe and at exploiting the many IGM-related sinergies between observational cosmology, galaxy formation and fundamental physics. The IGM is a unique cosmological observable as it probes 3/4 of the present age of the universe, it contains up to 80% of the baryons and is sensitive to scales that are not measured by other data. In the last decade, astronomical data sets have started to be widely used by the scientific community to address important physical issues such as: the nature of the dark matter and dark energy components and their evolution; the physical properties of the baryonic matter; variation of fundamental constants; feedback processes by galaxies, etc. For example, results obtained from astronomical data are nowadays comparable to those obtained by ground based physics laboratories (e.g. neutrino masses). This proposal will rely on observations of the IGM at high and low redshift and will interpret them by means of state-of-the-art computational facilities in order to firmly establish the (yet controversial) role of the IGM as a probe for cosmology and fundamental physics. Moreover, we aim at exploring the galaxy-IGM interplay at a crucial stage of the cosmic history when the universe was few Gyrs old and star forming galaxies were strongly affecting the dynamical, thermal and chemical properties of the IGM. The hosting institution, Trieste Observatory, and the Trieste Area (ICTP, SISSA and Trieste University) have a long-standing expertise on the topics above. We foresee that the present interdisciplinary proposal will have a strong scientific impact and will help the P.I. to consolidate its independence and to create his first research team.";891400;891400;ERC-2010-StG_20091028;/ERC-SG;ISTITUTO NAZIONALE DI ASTROFISICA;IT;;;"/PSE;/AER;/SPA";1;0;0;1;0;0 96836;264399;TRANSPOL;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-ITN;FP7;Transport and signalling in Polarized Cells;2010-12-01;2014-11-30;;Aberrant molecular signalling and intracellular trafficking are the molecular cause of many human diseases. TRANSPOL is an interdisciplinary initial stage training network (ITN) at the intersection of cell/molecular biology and membrane physics aimed specifically at the molecular understanding of the functional relationship between intracellular trafficking and cellular signalling and their relevance to human diseases. The importance of intracellular trafficking processes serving as an integral part of signalling has only recently received broader attention and demands further in-depth analysis. This ITN is specifically designed to bridge this gap between “conventional” signalling cascades and processes of membrane fusion, fission and intracellular trafficking. To tackle this important task we have assembled a unique multidisciplinary consortium combining top European scientists from the fields of cell biology, biochemistry, and physics as well as specialists from the private sector. The scientific objectives will concentrate on a better understanding of ligand/receptor-mediated signalling mechanism across the membrane, the lipid/protein interface in endocytosis, the signalling properties of endosomes, and deregulated trafficking and signalling pathways in disease. Three private enterprises are fully integrated in this ITN underlining its intersectorial character. The multidisciplinary research and training program comprises cell biology, protein and lipid biochemistry, biophysics, computational simulations, protein design and systems biology. TRANSPOL has designed a structured 3-year curriculum providing the following hallmarks: 1. A joined academic and industrial training program/2. A combination of local and network wide European training/3. A training in scientific and complementary skills including soft skills/4. An in-depth scientific training focused on a specific PhD topic/5. Doctoral examination under the auspices of external international examiners.;3835980;3835980;FP7-PEOPLE-2010-ITN;/MC-ITN;RUHR-UNIVERSITAET BOCHUM;DE;"JPK INTRUMENTS LIMITED;THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;THE UNIVERSITY OF SHEFFIELD;UNIVERSITE DE GENEVE;WEIZMANN INSTITUTE OF SCIENCE;BOEHRINGER INGELHEIM PHARMA GMBH &CO KG;Silantes GmbH;INSTITUT CURIE;SYDDANSK UNIVERSITET;INTERNATIONAL INSTITUTE OF MOLECULAR AND CELL BIOLOGY";"UK;CH;IL;DE;FR;DK;PL";"/EDU;/NET";1;0;0;1;0;0 95867;252682;KODKOD;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IOF;FP7;Forecasting conservation needs for endangered fauna:integrating landscape ecology and ethnoecology to predict habitat quality for the kodkod cat (Leopardus guigna) in the Chilean temperate rainforest;2010-06-01;2014-11-09;;Habitat loss, alteration and fragmentation represent severe threats to biodiversity globally. Wild cats, which generally require large areas over which to forage, are particularly affected by fragmentation and human-felid conflicts. Whereas considerable research has been directed towards large carnivores, smaller more cryptic species have received comparatively little attention. The kodkod or güi?a (Leopardus guigna) is the smallest of the neotropical cats and has one of the most restricted distributions known for felids occupying a narrow strip within south-central Chile and Argentina, the core area of indigenous Mapuche communities. The kodkod is classified as vulnerable by IUCN. Principal threats are habitat loss due to agricultural land use and retribution killing after attacks on poultry. The general aim of the project is to explore how projected future social and economic development of the fragmented and ethnically heterogeneous Araucanía region will affect habitat availability for the kodkod on private lands. An auto-ecological study will use radio-telemetry for the first time in the northern pre-Andean distribution range to assess habitat use, home range and activity patterns. An ethno-ecological study will provide understanding of the human environment context in which the kodkod lives. Through quantitative and qualitative interviews with Mapuche people and other socio-cultural groups of landowners knowledge and attitudes will be explored. Linking the ecological, ethnic and social information with geographic information, future land use scenarios will be modelled. This allows strategies to be identified for mitigating conflicts between the development process and habitat quality, and for the role of the kodkod as a cultural keystone species for use in conservation education. Training will be achieved in interdisciplinary aspects of biodiversity conservation (ethnoecology) and its methodologies (telemetry, Geographical Information Systems).;195681,5;195681,5;FP7-PEOPLE-2009-IOF;/MC-IOF;HELMHOLTZ-ZENTRUM FUER UMWELTFORSCHUNG GMBH - UFZ;DE;;;"/LIF;/EDU";1;0;0;1;0;0 89841;224766;COOPWEM;ONG;FP7-PEOPLE;PEOPLE-2007-2-2.ERG;FP7;Cooperative Water and Renewable Energies Management;2008-04-01;2011-03-31;;"COOPWEM directly goes back to the research needs identified during the implementation of the Marie-Curie project MTKD-CT-2004-014312 that has been implemented in CEIFA mostly under the scientific coordination of Mrs Suhita Osório-Peters. She was one of the guest researchers who joined our institution with a Marie-Curie stipend (Sept 2005 – Aug 2007). Before, she had more than 10 years full-time experience as a researcher in Germany. Her academic background is economics with a post-graduation in environmental sciences. She has excellent communication, coordination and leadership skills, and she really ‘thinks’ interdisciplinary. Our experience with her was excellent. Now, we jointly apply for a reintegration grant, in order to promote the framework conditions that ensure long-term job stability to Mrs Osório-Peters in our institution. COOPWEM is a research project with a duration of three years that addresses very topical issues and emphasizes an integrated approach of three complementary research areas: a) new instruments for the management of natural resources, b) local innovation systems and c) solidarity economy. By means of participatory approaches, it addresses the hypotheses that institutions based on cooperative arrangements are key elements of local innovation systems; still, the economic benefit of community based institutions is particularly important in the management of natural resources. It will focus on the analysis of the framework conditions that promote (or hinder) the implementation of new instruments in the field of natural resources management in Portugal. In particular, it will analyse the role of water users’ associations (WUA), as well as that of small scaled energy producers’ cooperatives, for sustainable regional development. Since CEIFA wants to enlarge its service offer into the areas of water and renewable energies management, COOPWEM perfectly links Mrs Osório-Peters own career development plan with the strategic goals of our enterprise.";45000;45000;FP7-PEOPLE-2007-2-2-ERG;/MC-ERG;CENTRO DE ESTUDOS INFORMACAEO E FORMACAEO PARA O AMBIENTE;PT;;;"/SCI;/EDU";1;0;0;1;0;0 105885;309706;EVOEPIC;ONG;FP7-IDEAS-ERC;ERC-SG-LS2;FP7;Evolutionary mechanisms of epigenomic and chromosomal aberrations in cancer;2012-12-01;2017-11-30;;Our working hypothesis is that tumorigenesis is an evolutionary process that fundamentally couples few major driving events (point mutations, rearrangements) with a complex flux of minor aberrations, many of which are epigenetic. We believe that these minor events are critical factors in the emergence of the cancer phenotype, and that understanding them is essential to the characterization of the disease. In particular, we hypothesize that a quantitative and principled evolutionary model for carcinogenesis is imperative for understanding the heterogeneity within tumor cell populations and predicting the effects of cancer therapies. We will therefore develop an interdisciplinary scheme that combines theoretical models of cancer evolution with in vitro evolutionary experiments and new methods for assaying the population heterogeneity of epigenomic organization. By developing techniques to interrogate DNA methylation and its interaction with other key epigenetic marks at the single-cell level, we will allow quantitative theoretical predictions to be scrutinized and refined. By combining models describing epigenetic aberrations with direct measurements of chromatin organization using Hi-C and 4C-seq, we shall revisit fundamental questions on the causative nature of epigenetic changes during carcinogenesis. Ultimately, we will apply both theoretical and experimental methodologies to assay and characterize the evolutionary histories of tumor cell populations from multiple mouse models and clinical patient samples.;1499998;1499998;ERC-2012-StG_20111109;/ERC-SG;WEIZMANN INSTITUTE OF SCIENCE;IL;;;"/BIO;/LIF";1;0;0;1;0;0 99237;267223;IFP-MUST;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-COFUND;FP7;International Fellowship Program on Molecular Ultrafast Science and Technology;2011-05-01;2015-04-30;;"MUST is an interdisciplinary network of Swiss research groups, all with research efforts in ultrafast science. In Switzerland, ultrafast science has reached a critical mass of individual research efforts, spread out over various universities and research centers. In almost all key technologies and in theoretical modeling, Swiss research groups are among the leaders in the field and represent a very complementary set of experimental and theoretical teams. In the future, our society faces a number of key challenges, such as developing alternative energy sources, synthesizing complex functional drugs, or designing post-Moore's law electronics. Addressing these challenges requires a detailed microscopic understanding of the structural and dynamic behavior of matter. This understanding can only come from sophisticated and advanced visualization techniques, which the members of MUST will help to develop within a highly integrated research network. Here, we propose to establish an International Fellowship Program on Molecular Ultrafast Science and Technology (IFP-MUST) integrated in and fed by our national network of research teams. It is our vision that novel technologies, advanced modeling techniques, and the spirit of our thriving network would create an ideal environment for high-level postdoctoral research projects. Our program will provide Europe with a new generation of researchers in ultrafast sciences and therefore considerably improve the research quality of the ERA. It is our goal to attract about 75% of all postdoctoral fellows from all around the world (incoming), while having the option to reintegrate European researchers who have worked oversees into a European research environment (25%).";2998170;1199268;FP7-PEOPLE-2010-COFUND;/MC-COFUND;UNIVERSITAET BERN;CH;;;"/SOC;/COO;/NET";1;0;0;1;0;0 108177;326051;TransDRiM;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IEF;FP7;Transboundary Drought Risk Management - an application to the Guadiana River Basin;2013-10-01;2015-09-30;;"TransDRiM is an advanced training and research project focused on transboundary drought management at the river basin scale, in the context of the Water Framework Directive implementation. The proposed methodologies are applied to the Guadiana river basin, the fourth largest within the Iberian Peninsula, where shared watersheds between Portugal and Spain account for over 2/3 of its territory. The Guadiana is of particular interest because of its relative aridity, water scarcity, and high drought risk conditions. A political agreement (the Albufeira Convention) regulates cooperation and conflicts on water issues between the two countries, but an exception regime is applied under drought conditions – thus, when most needed, common management is reduced to a minimum. Furthermore, water planning remains strictly at the national level, and public participation continues to be insignificant, contrary to the WFD guidelines. TransDRiM seeks to minimize environmental, social and economic impacts of cross-border drought events, reduce potential conflicts on water uses and availability between both riparian countries, and provide a methodological framework for transboundary drought risk management across EU river basins. In order to reach these goals, the following specific research objectives will be pursued: Identify the potential and constraints for a transboundary policy of drought risk management; Assess the compatibility of the two national planning structures; Provide technical solutions to establish a transboundary and operational drought management framework; Assess the feasibility of transboundary drought response measures proposed, based on their economic, political and social criteria. TransDRiM will address these tasks based on a territorial and interdisciplinary approach, learning from both the host experience in the subject, the tailored training programme based on GIS and other integrative tools, and the researcher ability to work on an international context.";173370,6;173370,6;FP7-PEOPLE-2012-IEF;/MC-IEF;UNIVERSIDAD DE SEVILLA;ES;;;/SCI;1;0;0;1;0;0 97747;246874;BLACKSEAHAZNET;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IRSES;FP7;Complex Research of Earthquake’s Prediction Possibilities, Seismicity and Climate Change Correlations;2011-01-01;2013-12-31;;The purpose of project BlackSeaHazNet is development of long-term research cooperation through coordinated joint program of researcher’s exchange. The base is Complex Program for research of possibility for forecast earthquake’s time, place (epicenter, depth), magnitude and intensity using reliable precursors. Precursors research includes regional geophysical and seismological monitoring, monitoring of water sources and their Radon, Helium, Mercury concentrations, crust temperature, monitoring of electromagnetic field under, on, and above Earth surface, meteorological monitoring, including earthquake clouds and electrical charge distributions, near space monitoring, aimed to estimate Earth, Sun and space (cosmic rays) origins of variations, and biological precursors. For many variables well working monitoring exists (for example INTERMAGNET geomagnetic field monitoring). For others (for example: monitoring of Earth currents distribution) monitoring have to be created. Due to complex real time variables monitoring the parallel output of the Program can be different time scale estimations for other natural hazards and risk assessment, as well as the correlations between human behavior and electromagnetic and other geophysical variables variations. Proposed regional network can be considered as first step for creating wide interdisciplinary scientific consortia for formulation of more adequate models of today Climate change, Earth seismic processes as well as different time scales regional earthquakes forecasts. Which will the bases for future EC framework , regional and bilateral Projects. The scientific and practical results will be considered in workshops and regional training seminars.;475200;475200;FP7-PEOPLE-2009-IRSES;/MC-IRSES;INSTITUTE OF NUCLEAR RESEARCH AND NUCLEAR ENERGY - BULGARIAN ACADEMY OF SCIENCES;BG;"SPACE RESEARCH AND TECHNOLOGY INSTITUTE;INSTITUT JOZEF STEFAN;HELLENIC CENTRE FOR MARINE RESEARCH;TURKIYE BILIMSEL VE TEKNOLOJIK ARASTIRMA KURUMU;GEOLOGICHESKI INSTITUT PRI BAN ST.DIMITROV;NATIONAL INSTITUTE OF GEOPHYSICS GEODESY AND GEOGRAPHY - BULGARIAN ACADEMY OF SCIENCES;Ss. CYRIL AND METHODIUS UNIVERSITY IN SKOPJE;ZNANSTVENORAZISKOVALNI CENTER SLOVENSKE AKADEMIJE ZNANOSTI IN UMETNOSTI";"BG;SI;EL;TR;MK";"/SCI;/EDU;/ITT";1;0;0;1;0;0 104322;302799;DIME4HERITAGE;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IOF;FP7;Digital Media for Heritage: Refocusing Design from the Technology to the Visitor Experience;2012-10-01;2015-09-30;;"The 21st century museum mission has been re-interpreted. Heritage institutions are called to improve and find new ways to present content in order to convey knowledge and engage visitors. Arguably, digital media have an increasingly prominent role in the communication and interpretation of heritage while digital technology continuously improves. But can technical innovation alone yield new communication and interpretation approaches that enrich the visitor experience? Now is the time to question and rethink digital media design practices for better experiences of visitors. Design Culture is the key-discipline to deal with this challenge, as design is opening up pathways to the disciplines needed to connect and integrate knowledge from many specialisations: the design of effective and innovative digital media-based communication for cultural heritage requires working across the borders of museology, visitor studies, and design. Digital media design requires careful attention to the orchestration of a number of disciplines to result in an apposite visitor experience: the interdisciplinary research we propose aims to drive innovation by generating: (a) a framework for this orchestration and (b) methodologies for the design of effective digital media for heritage. The combination of the two parts will set the basis for a museum digital media design theory. Our methodology is tuned to theory building and combines analytical conceptual research with empirical case studies in order to test the conceptual framework and the methodology. Results include (a) a conceptual framework through which factors involved in design can be articulated in a way that provides a common design-oriented frame of reference; (b) innovative design methodology that encompasses design principles, guidelines, and methods; (c) museum design problem case studies as exemplars addressing contemporary museological issues; and (d) knowledge transfer workshops for museum design practitioners.";271943,7;271943,7;FP7-PEOPLE-2011-IOF;/MC-IOF;UNIVERSITY OF LEICESTER;UK;;;/SCI;1;0;0;1;0;0 96684;257638;PAGAP;ONG;FP7-IDEAS-ERC;ERC-SG-PE1;FP7;Periods in Algebraic Geometry and Physics;2010-11-01;2015-10-31;;"Periods are the integrals of algebraic differential forms over domains defined by polynomial inequalities, and are ubiquitous in mathematics and physics. One of the simplest classes of periods are given by multiple zeta values, which are the periods of moduli spaces M_{0,n} of curves of genus zero. They have recently undergone a huge revival of interest, and occur in number theory, the theory of mixed Tate motives, knot invariants, quantum groups, deformation quantization and many more branches of mathematics and physics. Remarkably, it has been observed experimentally that Feynman amplitudes in quantum field theories typically evaluate numerically to multiple zeta values and polylogarithms (which are the iterated integrals on M_{0,n}), and a huge amount of effort is presently devoted to computations of such amplitudes in order to provide predictions for particle collider experiments. A deeper understanding of the reason for the appearance of the same mathematical objects in algebraic geometry and physics is essential to streamline these computations, and ultimately tackle the outstanding problems in particle physics. The proposal has two parts: firstly to undertake a systematic study of the periods and iterated integrals on higher genus moduli spaces M_{g,n} and related varieties, and secondly to relate these fundamental mathematical objects to quantum field theories, bringing to bear modern techniques from algebraic geometry, Hodge theory, and motives to this emerging interdisciplinary area. Part of this would involve the implementation (with the assistance of future postdoc. team members) of an algorithm for the evaluation of Feynman diagrams which is due to the author and goes several orders beyond what has previously been possible, in order eventually to deduce concrete predictions for the Large Hadron Collider.";1068540;1068540;ERC-2010-StG_20091028;/ERC-SG;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FR;;;"/PSE;/MST";1;0;0;1;0;0 106655;306652;SpinBound;ONG;FP7-IDEAS-ERC;ERC-SG-PE3;FP7;Exploring the Spin Physics at the Boundaries of Materials with Strong Spin-Orbit Interaction;2013-02-01;2018-01-31;;"I propose to investigate a new research frontier on spin physics at the boundaries (surfaces) of materials with strong spin-orbit interaction (SOI). Although the properties of these materials have been studied for more than half a century, researchers are just starting to grasp the richness of SOI phenomena that occur at them. SOI leads to surface and boundary states with unusually large spin splitting in simple heavy elements. It can also produce a nontrivial topology in band insulators that brings about metallic surface states with exotic spin textures that are protected by time reversal symmetry. Despite their fundamental and technological interest, information on the nature of charge transport at such states is scarce, while spin transport remains unexplored. I plan to use our cutting-edge expertise on all-electrical lateral spin injection and detection methods to unravel the spin dynamics in them, providing a wealth of information that could not be otherwise obtained. A comprehensive set of objectives will include material integration with ferromagnets and insulators, and innovative devices and measurement protocols. My team will gather information on injection, accumulation, scattering and relaxation processes of spins in the surface and boundary states. Complementary experiments will focus on current-induced spin-torque on a contacting ferromagnet and will address the question of whether spin-split metallic surfaces can enable spin information processing when deposited onto semiconductors. This is a highly challenging project, with a strong interdisciplinary nature across physical and material sciences that will open new avenues for the realization of exotic states of matter such as axions and Majorana fermions. While the research program is driven by the quest for fundamental understanding, new directions for applications could emerge from our basic science results.";1628744;1628744;ERC-2012-StG_20111012;/ERC-SG;FUNDACIO INSTITUT CATALA DE NANOCIENCIA I NANOTECNOLOGIA;ES;;;"/PSE;/ELM;/NNT";1;0;0;1;0;0 101187;289355;PicoSEC-MCNet;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-ITN;FP7;Pico-second Silicon photomultiplier-Electronics- & Crystal research-Marie-Curie-Network;2011-12-01;2015-11-30;;We propose to establish a special detector-training network aiming to extend the application of cutting-edge technologies developed in High Energy Physics (HEP) to other domains, such as medical imaging. A large number of detector techniques, developed for and used in particle physics experiments, has been transferred successfully to other fields. Most prominent are their applications in medicine, X-ray imaging, materials research, astrophysics and others. These technological spin-offs are of highest value for society and will be a focal point in this Network. Not only for positron emission tomography (PET), the Network will likewise respond to the need to develop new ultra-fast photo-detection for the future generation of linear colliders with unprecedented beam intensities. The Multi-Site Network, to be coordinated by CERN, would be an interdisciplinary, multi-national initiative whose main goal is to train young researchers in the domain of novel high-speed photo-detection instruments in HEP calorimetry and also to make use of photon time of flight (TOF) in PET, thus enabling us for the first time to considerably enhance image quality with instant benefits to patients and medical institutions. This multi-site ITN comprises 11 full partners, 7 in academia and 4 in the private sector, known world-wide in the fields of frontier detector technologies, photo detection techniques and novel scintillator production methods, as well as in the domain of semiconductor technology, medical instrumentation, image reconstruction and fusion, and surgical tracking and navigation. As such, the Network combines the necessary competence, expertise and infrastructure for top-level training of young researchers. It is foreseen to hire 18 Early Stage Researchers (ESRs) plus 4 Experienced Researchers (ERs) and structure the training project into five principle research-oriented work packages, and three work package for management, training and outreach.;5699664,46;5699664,46;FP7-PEOPLE-2011-ITN;/MC-ITN;EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH;CH;"FIBERCRYST SAS;TECHNISCHE UNIVERSITAET MUENCHEN;RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG;LABORATORIO DE INSTRUMENTACAO E FISICA EXPERIMENTAL DE PARTICULAS;UNIVERSITA' DEGLI STUDI DI MILANO-BICOCCA;KLOE SA;STMICROELECTRONICS SRL;STIFTUNG DEUTSCHES ELEKTRONEN-SYNCHROTRON DESY;TECHNISCHE UNIVERSITEIT DELFT;SURGICEYE GMBH";"FR;DE;PT;IT;NL";"/LIF;/SCI";1;0;0;1;0;0 98418;274326;EARLYUNIVERSE;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-IEF;FP7;Early Universe Modelling and Confrontation with Cosmological Data;2011-10-01;2013-09-30;;In this exploratory project we will study the non-trivial interrelations between fundamental theory, phenomenology and observation in cosmology, in order to obtain a comprehensive picture of the physics of the early universe, and to identify new promising directions for future research. The project will develop along three interrelated lines of work. First, we will seek new possibilities for cosmological model building in string theory and explore the range of phenomenological features that theory allows. One focal point will be our model of Wilson line inflation, which offers a new path for understanding inflation in heterotic theory - an open problem - and which presents rich phenomenology, including non-Gaussianity and gravitational waves. This connects to our second line of work, which is a quantitative study of the phenomenological features of new and existing models. We will focus on hybrid 2-field models that are both well-motivated and phenomenologically rich, producing isocurvature modes, non-Gaussianity and cosmic strings. We will study these features quantitatively and use our state of the art string evolution model to quantify observational signals coming from cosmic strings. Third, we will explore non-trivial relations between high-energy physics sectors that do not play a dominant role in the early universe, but are part of the same underlying theory and can produce observable signals in the late universe. We will use high quality data in innovative ways to constrain high-energy parameters in the underlying fundamental theory. We shall give special attention to axions (e.g. from type IIB string theory used to build the 2-field models mentioned above) and their coupling to photons, fermions and gravitons. This is an interdisciplinary project combining information from theory, phenomenology and observation to maximize impact. There are many connections between the different lines of work and unexplored areas where new promising directions could be found.;193349,6;193349,6;FP7-PEOPLE-2010-IEF;/MC-IEF;THE UNIVERSITY OF NOTTINGHAM;UK;;;"/EMP;/EDU;/NET";1;0;0;1;0;0 95302;258203;SMART-EC;CLO;FP7-ICT;ICT-2009.3.9;FP7;Heterogeneous integration of autonomous smart films based on electrochromic transistors;2010-09-01;2014-08-31;;"SMART-EC aims at the development of self powered (energy harvesting and storage) EC device integrating EC thin film transistor component on a flexible substrate for energy saving, comfort and security in automotive, e-cards and smart packaging sectors.The objective is to overcome the current limitations related to low switching time and manufacturing costs; the switching time can be reduced (<1s) by introducing nanostructured EC materials, innovative EC transistors and high ionic conductive solid electrolytes. Radical innovative cheap manufacturing technologies on large area PVD, inkjet and roll-to-roll processes on low cost plastic will be developed. These processes are fully compatible with heterogeneous integration of several functions to produce a completely autonomous device (thin film battery, PV cell, sensors and communication) with great added value respect to traditional solutions. The optimization of co-integrated (separated building blocks laminated together) and convergence (using same materials for different building blocks) approaches will allow to fabricate a fully autonomous system. The first step will be the optimization of deposition and patterning technologies in terms of processes parameters and in-situ monitoring to allow the high control of film growth; the second step will be the heterogeneous integration of the different building blocks to produce the self-powered systems for the targeted applications.Four academic and research institutes guarantee a high level interdisciplinary research on solid-state physics, material chemistry and integration; this will assures the proper technology transfer to industrial partners at all product chain levels (materials, devices and end users) for a successful exploitation of results. SMART-EC materials and technologies are original and will pave the way for future generation smart surfaces with great potential impact at medium and long term (flexible and transparent electronics) applications.";7255666;5100000;FP7-ICT-2009-5;/CP;CENTRO RICERCHE FIAT SCPA;IT;"ROCKWOOD PIGMENTS (UK) LIMITED;RISE ACREO AB;BIOAGE SRL;ORBOTECH LTD;BUNDESDRUCKEREI GMBH;FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.;G24 INNOVATIONS LTD;COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES;SOLEMS SA;PLASTIQUES RG SAS;VIT SA;UNINOVA-INSTITUTO DE DESENVOLVIMENTO DE NOVAS TECNOLOGIAS-ASSOCIACAO;POLITECNICO DI TORINO";"UK;SE;IT;IL;DE;FR;PT";"/ELM;/ITT";1;0;0;1;0;0 95186;254143;MONO-U4;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IIF;FP7;Microbial and Geochemical Factors influencing the speciation of uranium in the subsurface;2010-06-01;2012-05-31;;The remediation of uranium-contaminated sediments and aquifers remains a major environmental challenge, yet the processes that control uranium speciation and mobility in the subsurface remain largely unknown. In anoxic systems, two major processes may lead to uranium reduction: direct electron transfer via bacterial metabolism or indirect electron transfer from microbially- reduced metals. Our initial experiments confirm that bacterial reduction of U(VI) may lead to the stable mineral uraninite (UO2), but in some cases a non-uraninite U(IV) species is produced. This species has been dubbed ‘monomeric U(IV)’ due to the absence of a feature in the x-ray absorption spectrum that is characteristic of the U-U interaction found in uraninite. The presence of this monomeric U(IV) species is an important development because is expected to be less stable than uraninite. Thus, its formation may have critical implications for predicting uranium immobilization in the subsurface. Here we propose an interdisciplinary project, utilizing tools from microbiology, geochemistry, and spectroscopy, to determine the conditions that mediate the formation of non-uraninite U(IV). We will initially conduct batch experiments with several bacterial species, both in the presence and absence of iron as an electron acceptor, and monitor the production of iron and uranium precipitates. Using a suite of tools including transmission electron microscopy, selected area electron diffraction, Mössbauer spectroscopy, and extended x-ray absorbance fine structure, we will identify the speciation of reduced uranium and the mechanisms that control its reduction. Based on these results, we will conduct a series of uranium flow-through column studies to more closely simulate natural conditions. The results of these studies will help in planning environmental remediation strategies at uranium-contaminated locations and in nuclear repository design.;174065,2;174065,2;FP7-PEOPLE-2009-IIF;/MC-IIF;ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE;CH;;;"/SCI;/EDU;/ITT";1;0;0;1;0;0 101225;275778;ENGAGING EU CITIZENS;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-IEF;FP7;How to involve the European citizenry in European politics? Emotions, media discourse, and mobilisation;2012-01-01;2016-05-28;;"The research project sets out to describe the mechanism that explains how political entrepreneurs created mass mobilisations by engaging European citizens against Haider's FPÖ, against the Bolkestein directive, and against Turkish membership. The lack of citizen participation is often assumed to be the main problem of democracy at the European level. The recent mass mobilisations are puzzling, as not much has changed in the circumstances that were thought to cause the apathy of citizens towards European politics. Contrary to the actor- and structure-centred accounts found in the European integration literature, this research project focuses on the activating quality of emotionally-loaded media discourse by incorporating insights from media effect theory and collective action theory. While it is known how citizens become politically engaged with national politics, the peculiarity of multi-level European decision-making, and, especially, the profoundly different political opportunity structure for mobilisation on European issues need to be taken into account. Knowledge on the necessary circumstances for engaging citizens with European politics is elicited by comparing three issues with high levels of mobilisation to three similar issues with low levels of mobilisation. Media discourse and citizens' political behaviour in Germany, France and Switzerland is analysed via a qualitative and quantitative content analysis and by consulting social movement databases. The non-EU Switzerland serves as a validity check. Subsequently, an experiment with a pre-test/post-test design is held to test the main independent variables related to emotionally-loaded media discourse, while controlling for the relevant intervening variables. By disclosing whether politicisation is the prerogative of Eurosceptics, or may lead to the kind of contestation beneficial to democratic politics, this interdisciplinary project will disclose the prospects for civic participation in European politics.";162163,2;162163,2;FP7-PEOPLE-2010-IEF;/MC-IEF;FREIE UNIVERSITAET BERLIN;DE;;;"/EMP;/EDU;/NET";1;0;0;1;0;0 109952;335739;FIELDS-KNOTS;ONG;FP7-IDEAS-ERC;ERC-SG-PE2;FP7;Quantum fields and knot homologies;2013-12-01;2018-11-30;;"This project is concerned with fundamental problems arising at the interface of quantum field theory, knot theory, and the theory of random matrices. The main aim of the project is to understand two of the most profound phenomena in physics and mathematics, namely quantization and categorification, and to establish an explicit and rigorous framework where they come into play in an interrelated fashion. The project and its aims focus on the following areas: - Knot homologies and superpolynomials. The aim of the project in this area is to determine homological knot invariants and to derive an explicit form of colored superpolynomials for a large class of knots and links. - Super-A-polynomial. The aim of the project in this area is to develop a theory of the super-A-polynomial, to find an explicit form of the super-A-polynomial for a large class of knots, and to understand its properties. - Three-dimensional supersymmetric N=2 theories. This project aims to find and understand dualities between theories in this class, in particular theories related to knots by 3d-3d duality, and to generalize this duality to the level of homological knot invariants. - Topological recursion and quantization. The project aims to develop a quantization procedure based on the topological recursion, to demonstrate its consistency with knot-theoretic quantization of A-polynomials, and to generalize this quantization scheme to super-A-polynomials. All these research areas are connected via remarkable dualities unraveled very recently by physicists and mathematicians. The project is interdisciplinary and aims to reach the above goals by taking advantage of these dualities, and through simultaneous and complementary development in quantum field theory, knot theory, and random matrix theory, in collaboration with renowned experts in each of those fields.";1345080;1345080;ERC-2013-StG;/ERC-SG;UNIWERSYTET WARSZAWSKI;PL;"INSTITUTE FOR ADVANCED STUDY - LOUIS BAMBERGER AND MRS FELIX FULD FOUNDATION CORPORATION;ASSOCIACAO DO INSTITUTO SUPERIOR TECNICO PARA A INVESTIGACAO E DESENVOLVIMENTO;THE REGENTS OF THE UNIVERSITY OF CALIFORNIA";"US;PT";"/PSE;/SCI";1;0;0;1;0;0 192350;631399;SENSE;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-CIG;FP7;Structure and Ecological Niche in the Soil Environment;2014-11-01;2018-10-31;;SENSE (Structure and Ecological Niche in the Soil Environment) is a groundbreaking project to discover the processes affecting soil animal diversity and how soil biodiversity affects ecosystem stability and function. SENSE tackles the challenging enigma of soil animal diversity (exceptionally high diversity in an apparently much less diverse environment), studying the effect of soil structural complexity on community assembly processes. The resulting knowledge will allow the development of a new generation of food web models that takes into account the complex nature of aboveground–belowground linkages, and astonishing levels of belowground diversity. These models are fundamental to the study of ecosystem stability and function. This is a key topic in the framework of EU bioeconomy research and innovation: soil is under threat (e.g. compaction) and provides humans with key services that currently are at risk. This multidisciplinary project involves approaches that range from chemistry and physics to molecular and theoretical ecology. The knowledge it provides promotes an interdisciplinary approach to management and conservation strategy (e.g. protection of soil biodiversity through the preservation of soil structure). In fact, the project creates the conditions to bridge basic, foundational ecology and classical soil ecology, which traditionally has a more applied focus. SENSE will promote the formation of an international network of scientists that will contribute to the project through workshops, research visits, and direct involvement in the measurement of key variables and outreach programs. Thanks to this networking and its outputs, I will establish high profile research themed around the study of biodiversity. Thus, in the long term I will be able to create a leading, internationally recognised research group in the framework of on-going, worldwide research collaborations that are taking place among leading soil ecologists and biodiversity scientists.;100000;100000;FP7-PEOPLE-2013-CIG;/MC-CIG;THE QUEEN'S UNIVERSITY OF BELFAST;UK;;;/LIF;1;0;0;1;0;0 92111;236632;ERIS;ONG;FP7-PEOPLE;FP7-PEOPLE-IOF-2008;FP7;Experimental Resource for the Investigation of dialogue procesSes;2010-01-01;2012-12-31;;"The primary goal of ERIS is training-through-research under supervision by two of the world's leading dialogue researchers. This will enable the fellow to expand his repertoire of experimental methods, including obtaining training in specific forms of experimental design, training in statistical analysis, complementary skills training, and exposure to new experimental problems at Stanford and Edinburgh. The vehicle for this training consists of an experimental programme that addresses key problems in dialogue research: the role of clarification requests, acknowledgements, disfluencies, alignment, semantic co-ordination and language change, in dialogue and multilogue. Central to this programme is the development and refinement of the use of text-based dialogue as an experimental methodology into a fully-integrated experimental resource that supports interdisciplinary collaboration between multiple research institutes. It will enable the fine-grained, context-sensitive manipulation of between- and within-turn phenomena of multi-party dialogue. The skills and knowledge acquired during the Outgoing phase, together with feedback from the international distribution network, will be incorporated into the experimental resource, which will include a repository of experimental tasks and interventions. On returning to Edinburgh, the experimental resource will be disseminated to the wider dialogue research community.";237878,97;237878,97;FP7-PEOPLE-IOF-2008;/MC-IOF;THE UNIVERSITY OF EDINBURGH;UK;;;"/COO;/EDU";1;0;0;1;0;0 89743;227756;DIPOLAR ROTOR ARRAY;ONG;FP7-IDEAS-ERC;ERC-AG-PE5;FP7;Regular Arrays of Artificial Surface-Mounted Dipolar Molecular Rotors;2009-02-01;2014-07-31;;We propose a feasibility demonstration of an unprecedented concept: preparation of regular two-dimensional arrays of artificial surface-mounted dipolar molecular rotors and control of their coherent motion by the application of an outside electric field. The proposal involves a highly interdisciplinary endeavor, which requires experience in synthesis (preparation of molecular rotors), surface chemistry (assembly of rotors into arrays on surfaces), surface spectroscopy and scanning microscopy (characterization of rotor arrays on surfaces), and theory (modeling of rotor dynamics). The principal investigator is presently actively working and publishing in all of these subdisciplines.;2457600;2457600;ERC-2008-AdG;/ERC-AG;USTAV ORGANICKE CHEMIE A BIOCHEMIE, AV CR, V.V.I.;CZ;;;"/PSE;/MAT;/IND";1;0;0;1;0;0 110398;912563;BVPSYMMETRY;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IIF;FP7;Reductions and exact solutions of boundary value problems with moving boundaries by means of symmetry based methods;2016-05-10;2017-05-09;;"Boundary value problems with moving boundaries are widely used in mathematical modeling a huge number of processes, which arise in physics, biology and industry. While these processes can be very different from a formal point of view, they have the common peculiarity: unknown moving boundaries. The most important subclass of such boundary value problems (BVPs) is the Stefan problems, in which the movement of unknown boundaries is governed by the well-known Stefan boundary conditions. BVPs with moving boundaries, particularly the multidimensional Stefan problems, are the main object of the proposed project. Developing new theoretical foundations and algorithms for reduction of such BVPs to those of lower dimensionality and construction of exact solutions of BVPs in question is the main aim of the project. Applied goal is to compare the analytical results derived with those obtained by means of the appropriate numerical techniques in the case of a wide range of the physically and biologically motivated problems. Moreover such comparison will demonstrate the real interdisciplinary aspect of the proposal. The novel idea of the project is to develop the algorithms mentioned above using such symmetry based methods as the classical Lie-Ovsiannikov method, the Bluman-Cole method of non-classical symmetry, conditional symmetry method and their recent extensions. The main results to be achieved: new definitions of (generalized) conditional invariance for BVPs with a wide range of boundary conditions will be derived; algorithms for how to construct all possible conditional symmetries for the given class of BVPs will be determined; new analytical results (conditional symmetries, reductions and exact solutions of BVPs) will be established by application of the algorithm to a wide range of nonlinear BVPs modeling the tumour growth processes and melting-evaporation processes.";15000;15000;FP7-PEOPLE-2012-IIF;/MC-IIFR;INSTITUTE OF MATHEMATICS OF THE NATIONAL ACADEMY OF SCIENCES OF UKRAINE;UA;;;/SCI;1;0;0;1;0;0 110163;330111;LNCRNADROCNS;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IIF;FP7;Long Non-coding RNAs with specific regulation and function in the Drosophila Central Nervous System;2014-07-01;2017-03-17;;"The scientific and technical breakthrough of the draft sequence of the human genome in 2001 and the advent of genome wide technologies have dramatically altered our view of genome organization and function. We know now that more than 70% of the human genome is transcribed, although only 2% encode proteins. Within this huge percentage of supposedly “garbage” transcripts, thousands of long non-coding RNAs (lncRNAs) have been described. lncRNAs are characterized by their extensive regulation during development, particularly in the central nervous system (CNS), where some have been shown to affect cognitive and locomotor functions. Drosophila melanogaster is an ideal model for studying the role of lncRNAs during development and has been used successfully to investigate the molecular and cellular basis of neurodegenerative disorders. To address the relevance and functions of lncRNAs during CNS development, we plan to identify and characterize lncRNAs in Drosophila neurons by applying several innovative, robust, and genome wide technologies. Taking advantage of the power of Drosophila genetics, we will study the in vivo roles of selected CNS lncRNAs, at both the morphological and functional levels, in two mushroom body (MB) neuron paradigms. Using the most modern instruments and methods available, we will explore the neuronal functions of candidate CNS lncRNAs by their genetic knock-down and phenotypic analysis in vivo, analysis of their subcellular localization, trafficking and identification of their protein partners. To date, no systematic investigation of lncRNAs during CNS development addressing their expression patterns, localization and in vivo function in a living organism has been reported. Hence this interdisciplinary project, which will shed important insight into the biological functions of lncRNAs in the CNS, is both ambitious and novel.";161968,8;161968,8;FP7-PEOPLE-2012-IIF;/MC-IIF;EUROPEAN MOLECULAR BIOLOGY LABORATORY;DE;;;/SCI;1;0;0;1;0;0 192341;629076;COGVIM;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IEF;FP7;"WHY VISUAL METAPHORS MATTER: METAPHOR THEORY AND THE COGNITIVE GROUNDING OF VISUAL METAPHOR";2015-02-01;2017-01-31;;"'This study will elucidate what type of conceptual knowledge is shared between two concepts aligned in visual metaphors, and how this differs from verbal metaphors. It will provide novel insights on the structure and functioning of the human semantic memory and on state-of-the-art computational methods of knowledge representation, with special focus on the understanding of concepts expressed in the visual and verbal modality. Since conceptual knowledge derives from both our perceptual experiences and our linguistic encounters with the involved concepts, and since the two streams of information might not fully overlap, I argue that the modality in which a metaphor is expressed triggers different sets of semantic information about the involved concepts. By employing a computational, interdisciplinary Network-Approach, I will develop a model explaining visual metaphor’s cognitive grounding in bodily experiences. This allows me to investigate the contents of our knowledge about specific concepts, and highlight the overlapping features between source and target domains of visual and verbal metaphors in different environments. I argue that the interpretation of visual metaphors might rely on conceptual knowledge that is not necessarily encoded in linguistic structures, nor commonly used in verbal communication. Bringing together the embodied theory of cognition (conceptual knowledge is rooted in bodily experiences) and the distributional Hp (words that appear in similar contexts have similar meanings), enables me to analyze the concepts involved in visual and verbal metaphors across three semantic databases accounting for: mental simulations, experiential, and linguistic contexts. The cross-disciplinary nature of this project, hosted at the prestigious Metaphor Lab lead by prof. Gerard Steen, and the Network Institute at the VU Amsterdam, will make me a bridging scholar between different disciplines: metaphor studies, cognitive, and computational linguistics.'";183469,8;183469,8;FP7-PEOPLE-2013-IEF;/MC-IEF;UNIVERSITEIT VAN AMSTERDAM;NL;;;;1;0;0;1;0;0 110236;336506;CEMOS;ONG;FP7-IDEAS-ERC;ERC-SG-PE8;FP7;Crystal Engineering for Molecular Organic Semiconductors;2014-01-01;2018-12-31;;'The urgent need to develop inexpensive and ubiquitous solar energy conversion cannot be overstated. Solution processed organic semiconductors can enable this goal as they support drastically less expensive fabrication techniques compared to traditional semiconductors. Molecular organic semiconductors (MOSs) offer many advantages to their more-common pi-conjugated polymer counterparts, however a clear and fundamental challenge to enable the goal of high performance solution-processable molecular organic semiconductor devices is to develop the ability to control the crystal packing, crystalline domain size, and mixing ability (for multicomponent blends) in the thin-film device geometry. The CEMOS project will accomplish this by pioneering innovative methods of “bottom-up” crystal engineering for organic semiconductors. We will employ specifically tailored molecules designed to leverage both thermodynamic and kinetic aspects of molecular organic semiconductor systems to direct and control crystalline packing, promote crystallite nucleation, compatibilize disparate phases, and plasticize inelastic materials. We will demonstrate that our new classes of materials can enable the tuning of the charge carrier transport and morphology in MOS thin films, and we will evaluate their performance in actual thin-film transistor (TFT) and organic photovoltaic (OPV) devices. Our highly interdisciplinary approach, combining material synthesis and device fabrication/evaluation, will not only lead to improvements in the performance and stability of OPVs and TFTs but will also give deep insights into how the crystalline packing—independent from the molecular structure—affects the optoelectronic properties. The success of CEMOS will rapidly advance the performance of MOS devices by enabling reproducible and tuneable performance comparable to traditional semiconductors—but at radically lower processing costs.';1477472;1477472;ERC-2013-StG;/ERC-SG;ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE;CH;;;"/PSE;/EAR";1;0;0;1;0;0 103884;301919;REPEAT;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IOF;FP7;Repetition and Seriality in the Age of Television Studies 3.0;2012-06-01;2015-05-31;;"Researches in Media and Television Studies until today focus either on media industry, content, audiences or media technology. Recent developments regarding the globalization of television formats and the intermedial distribution and reception of television content via the internet and mobile media have been analyzed merely with regard to audience reception and participation. The research project ‘Repetition and Seriality in the Age of Television Studies 3.0’ will integrate all four dimensions of television to give an example of television in times of current global and intermedial transformations and will explore how these challenges effects European media landscape. This research objective should be achieved by the analysis of the recent phenomenon of transnational adaptations of television series in the US and Germany. REPEAT will analyze for which reasons television series are adapted by national channels or distributed globally, how the content and format of the series are transformed by transnational and intermedial adaptations and the series reception by audiences and critics. In comparison to preceding researches REPEAT will account for the multidimensional aspects of television productions by developing and extending the new interdisciplinary research methodology ‘Television Studies 3.0’ that is able to explain major current global challenges in media technology and its influence on society.";266289;266289;FP7-PEOPLE-2011-IOF;/MC-IOF;UNIVERSITAET POTSDAM;DE;;;/SCI;1;0;0;1;0;0 104963;317420;PROSENSE;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-ITN;FP7;Cancer Diagnosis: Parallel Sensing of Prostate Cancer Biomarkers;2012-10-01;2016-09-30;http://www.prosense-itn.eu/;"'The Marie Curie ITN 'Cancer Diagnostics: Parallel Sensing of Prostate Cancer Biomarkers' (PROSENSE) aims at training a new generation of young scientists in the interdisciplinary techniques and methods required to meet the major challenges in the development of diagnostic tools for prostate cancer. It will bring together training by experts from the biosensor technology area and those from life sciences and medicine that work on cancer biomarker research. PROSENSE is a coordinated research training network involving university groups, R&D sections of small and medium enterprises, research institutes, hospitals and the R&D section of a large enterprise from the biomedical field. PROSENSE is a unique programme bringing together training across disciplines and across sectors, complemented by researcher career development tools. The scientific aspects of PROSENSE are centred around the themes of: 1) Development and study of biomarkers; 2) Detection techniques development; 3) Probe immobilisation and characterisation; 4) System integration and validation. A full programme of cross-disciplinary and cross-sectoral secondments, traning and events will enable PROSENSE to promote interaction, knowledge exchange and collaboration in the multidisciplinary field of biosensor design with the aim of developing improved devices for prostate cancer diagnosis, prognosis and treatments. It will increase understanding of clinical relevance of prostate cancer biomarkers and elucidate how the concurrent analysis of biomarkers can inform therapy; improve sensitivity, selectivity, robustness and speed of biosensing technologies for the simultaneous screening of biomarkers; develop lab-on-a-chip devices requiring minute amounts of clinical samples and increase likelihood of viable fit-for-purpose prostate cancer biosensing products.'";4006853;4006853;FP7-PEOPLE-2012-ITN;/MC-ITN;UNIVERSITY OF BATH;UK;"DUBLIN CITY UNIVERSITY;HOCHSCHULE KAISERSLAUTERN;ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE;XEPTAGEN SPA;INESC MICROSISTEMAS E NANOTECNOLGIAS-INSTITUTO DE ENGENHARIA DE SISTEMAS DE COMPUTADORES PARA OS MICROSISTEMAS E AS NANOTECNOLOGIAS;Applied Enzyme Technology Limited;CARDIFF UNIVERSITY;CHEMICKY USTAV SLOVENSKEJ AKADEMIEVIED";"IE;DE;CH;IT;PT;UK;SK";/LIF;1;0;0;1;0;0 98583;277098;TDCCPCS;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-RG;FP7;Targeted delivery of charged membrane impermeant compounds to pain-sensing and cancer cells;2011-05-01;2015-04-30;;"Targeted delivery of therapeutic compounds to selective cell types is of great clinical importance and can minimize undesired side effects. Recently, we have introduced a way to target the delivery of sodium channel blockers selectively to nociceptive neurons, and thus capitalize on their effectiveness in blocking action potentials but now only at sites of pain generation. Using this approach we have been able to abolish the response to noxious mechanical and thermal stimuli without motor or tactile deficit (Binshtok et al., Nature). This approach represents a novel concept of targeted delivery and can be used to block activity and also to modulate intracellular signal transduction and metabolism pathways in pain- sensing neurons a well as cancer or any other large cation non-selective channels-expressing cells, while minimizing effects on other types of cells. We now need further explore the utility of this technique for clinical use as an analgesic and also see if the strategy can be used in more generalized way to targeted delivery of charger compounds, beyond charged local anesthetics, to specific types of cells. This project aims to develop methods for targeted delivery of charged local anesthetics to diminish inflammatory, postoperative and neuropathic pain. The second part of this project will be to examine different strategies to expand the approach to selectively target charged cytotoxic or antiproliferative compounds into cancer cells. This interdisciplinary project will incorporate imaging techniques and electrophysiological, histological and behavioral experiments. We believe that the results of our work will lead to a more effective treatment of pain with significantly fewer side effects. Furthermore targeted delivery of chemotherapeutic agents into tumor cell will improve their therapeutic index and hereby limits their side effects as well as the associated pain.";100000;100000;FP7-PEOPLE-2010-RG;/MC-IRG;THE HEBREW UNIVERSITY OF JERUSALEM;IL;;;/SCI;1;0;0;1;0;0 103259;298210;XBeBOA;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IOF;FP7;Extreme ultraviolet and X-ray spectroscopy to understand dynamics beyond the Born Oppenheimer Approximation;2012-04-03;2015-04-02;;"The Born Oppenheimer approximation (BOA) simplifies the electron-nuclear interaction by separation of their motion and is one of the milestones in the development of quantum physics and computational chemistry during the first half of the last century. Yet, in order to properly describe many chemical reactions, it is necessary to go beyond the BOA. Our research objective is to probe the electronic change in metal carbonyls during the passage of a conical intersection with ultrafast pulses in the extreme ultraviolet and soft x-ray range. The transitions induced by the highly energetic photons happen between an atomic core level of atoms inside a molecule and the molecular valence levels. Because of the spatially narrow core level, the transition is highly localized within an Angstrom or even less. Furthermore, the probe transition is element selective since the edges are markedly different for different elements. Equipped with this temporal and unprecedented spatial resolution, we will be able to advance the experimental the state-of-the-art and gain insight into the intricacies of non-BOA processes. The metal carbonyls under study have similarities with active centers in respiration and photosynthesis, and with the building blocks used for solar energy conversion, molecular electronics, magnetic data storage, light emitting diodes, dynamic cancer phototherapy and other subjects. This proposal has therefore a truly interdisciplinary basis and we believe that the lesson to be learned and the tools to be developed in the frame of this work will be fruitful in many fields such as physics, optics, materials science, chemistry, and biology.";264112,5;264112,5;FP7-PEOPLE-2011-IOF;/MC-IOF;ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE;CH;;;/SCI;1;0;0;1;0;0 110217;912652;GRASSLANDS;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IIF;FP7;The evolution of the Grassland biome: exploring past events to predict future scenarios;2015-09-01;2016-08-31;;Knowledge of the evolution of the grassland biome throughout the Earth's environmental history is important for the reconstruction of links between diversification/extinctions events and climate. Biomes are now being impacted by anthropogenic environmental change on an unprecedented scale, and one mean of understanding how component species will react is to study the effects of past environmental changes. Hence, understanding the evolutionary history of grassland ecosystems in the context of past biotic and abiotic changes is relevant to the way we will manage them under future environmental change. A new perspective on the history of the grassland biome is beginning to emerge from key developments in palaeontology and molecular phylogenetics that will be integrated interdisciplinary and multidisciplinary in the present project for the first time. GRASSLANDS aimed at understanding the timing and nature of grasslands' most important components, the grass (Poaceae) and daisy (Asteraceae) families, through the combination of fossil data, molecular phylogenetics and computational approaches. The potential contribution of GRASSLANDS to our understanding of the evolutionary history of these families and grassland ecosystems in general is significant and will certainly provide new insights into the rise of flowering plants as the dominant components of almost every terrestrial ecosystems.;15000;15000;FP7-PEOPLE-2012-IIF;/MC-IIFR;CONSEJO NACIONAL DE INVESTIGACIONES CIENTIFICAS Y TECNICAS (CONICET);AR;;;/SCI;1;0;0;1;0;0 102040;283938;POSTGLACIAL;ONG;FP7-IDEAS-ERC;ERC-SG-SH6;FP7;After the Ice: Postglacial hunter-gatherer lifeways;2012-01-01;2016-12-31;;"The period of rapid global warming that took place at the end of the last Ice Age in NW Europe must have posed dramatic challenges for hunter-gatherers. This project aims to integrate high-resolution records of palaeoclimatic and palaeoenvironmental change with the remarkable and newly emerging archaeological record of postglacial sites around palaeo-Lake Flixton, (Yorkshire, UK). Star Carr was first excavated in the 1940/50s and has since become internationally famous in the archaeological world for its remarkable discoveries. The site had been situated on the edge of a lake and the peat which had subsequently formed allowed excellent preservation of rare organic remains, a wooden platform of “brushwood”, a wooden platform/trackway made of split and hewn timbers (the earliest evidence of systematic carpentry in Europe) and the discovery of the oldest known structure/house in Britain. Recent excavation reveal that the site is much larger than previously imagined, the excavated area to date constituting less than 5% of the total occupation area. In addition, a less well-known site on the nearby Flixton Island also has potential to provide important information on occupation and adaptation to climate change during the early phases of the postglacial. There are 4 reasons why this site merits extensive excavation now. 1, The site is under serious risk of disappearing forever due to peat desiccation and fluctuating water table with unprecedented levels of acidity (below pH 3.0) which have seriously affected the organic remains; 2, I have assembled a strong team of interdisciplinary researchers; 3, further excavation will significantly push forward the frontiers of knowledge; 4, pilot studies demonstrate that palaeoclimatic and environmental proxy data survives and can be directly linked to human occupation episodes. It is a race against time, but here is still important and rare data to be collected from the Lake Flixton before it is too late.";1497780;1497780;ERC-2011-StG_20101124;/ERC-SG;UNIVERSITY OF YORK;UK;;;"/SCI;/SOC";1;0;0;1;0;0 106922;312368;DELPOWIO;ONG;FP7-IDEAS-ERC;ERC-SG-SH2;FP7;Delegation of Power to International Organizations and Institutional Empowerment over Time;2013-04-01;2019-03-31;;"In recent decades, there has been a steady increase in the number of international Organizations (IOs). At varying levels states have surrendered some authority to IOs, giving them different levels of institutional empowerment. While in the EU, IMF and World Bank there has been a steadily extension of their competences, in the GATT/WTO-Secretariat, NATO and WHO the degree of delegated authority has remained constant. How can we explain these different degrees of authority granted to IOs and their evolution over time? We argue that institutional empowerment is a function of temporal dynamics, the degree of cohesion among principals, and the institutional design of the delegation contract. On the theoretical side, the aim of the proposed interdisciplinary project is to produce theory-driven knowledge by developing a model of power delegation to IOs that integrates a temporal dimension into the principal-agent approach. This will be done by resorting to four different disciplines: political science, economics, law, and organizational sociology. On the empirical side, the main novelty of the project consists in adopting a comparative research design and a longitudinal perspective. We will analyse the institutional empowerment of six different IOs (EC/EU, GATT/WTO, IMF, WHO, UNESCO, and World Bank) over a period of 65 years (1950-2015). Given the aim and scope of this research, the project is to be regarded as theory-building and hypothesis-testing research. It will be based on extensive qualitative work conducted in the archives of these four IOs as well as on elite interviews with national and international officials. With this project we will gain new insights into the following fields: consequences of power delegation to IOs; temporal dimension of the interaction between states and IOs; preference formation of states; comparison of different types of IOs. This will allow us to answer the broader and more general question of the conditions under which IOs can operate as independent actors in world politics and to advance theoretical insights and empirical research in International Relations.";1293400;1293400;ERC-2012-StG_20111124;/ERC-SG;TECHNISCHE UNIVERSITAET MUENCHEN;DE;TECHNISCHE UNIVERSITAET DRESDEN;DE;/SOC;1;0;0;1;0;0 100156;280025;ACCLAIM;ONG;FP7-IDEAS-ERC;ERC-SG-PE10;FP7;Aerosols effects on convective clouds and climate;2011-09-01;2017-02-28;;"Clouds play a key role in the climate system. Small anthropogenic perturbations of the cloud system potentially have large radiative effects. Aerosols perturb the global radiation budget directly, by scattering and absorption, as well as indirectly, by the modification of cloud properties and occurrence. The applicability of traditional conceptual models of indirect aerosol effects to convective clouds is disputed as cloud dynamics complicates the picture. Strong evidence for numerous aerosol effects on convection has been established in individual disciplines: through remote sensing and in-situ observations as well as by cloud resolving and global modelling. However, a coherent scientific view of the effects of aerosols on convection has yet to be established. The primary objective of ACCLAIM is to recast the effects of aerosols on convective clouds as basis for improved global estimates of anthropogenic climate effects. Specific objectives include: i) to unravel the governing principles of aerosol effects on convective clouds; ii) provide quantitative constraints on satellite-retrieved relationships between convective clouds and aerosols; and ultimately iii) to enable global climate models to represent the full range of anthropogenic climate perturbations and quantify the climate response to aerosol effects on convective clouds. I have developed the research strategy of ACCLAIM to overcome disciplinary barriers in this frontier research area and seek five years of funding to establish an interdisciplinary, physics focused, research group consisting of two PostDocs, two PhD students and myself. ACCLAIM will be centred around global aerosol-convection climate modelling studies, complemented by research constraining aerosol-convection interactions through remote sensing and a process focused research strand, advancing fundamental understanding and global model parameterisations through high resolution aerosol-cloud modelling in synergy with in-situ observations.";1429243;1429243;ERC-2011-StG_20101014;/ERC-SG;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;UK;;;"/PSE;/ENV;/EAR";1;0;0;1;0;0 107275;331460;NANOART;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IEF;FP7;Nano Art Research Tool;2014-02-01;2016-01-31;;"“Our ordinary language has no means for describing a particular shade of colour” (Ludwig Wittgenstein in Philosophical Remarks, Chicago: The University of Chicago Press, 1984). This interdisciplinary project, combining Conservation Science, Nanotechnology, Restoration and Art History, aims to confront this problem regarding the binders applied in paintings, sculptures and illuminated manuscripts, which have a particularly diverse colour palette, rich in material terms as well as in symbolic and aesthetic values. Currently, the characterization of artwork binders (egg yolk, glair, gums and oils) requires microsampling combined with powerful but expensive techniques performed by specialized personnel. Despite all the advantages that nanotechnology has brought to molecular diagnostics and the healthcare industry in the recent years, the field of artwork preservation and conservation has not yet greatly benefited from nanobiosensing tools. The NANOART project will develop a nanobiosensor for the successful detection and identification of the biomolecules present in the paints of ancient artworks. This will lead to the development of a new and inexpensive “nanokit” based on gold nanoparticles which will allow to identify at point-of-care the nature of binders used in different artworks with an enhanced sensitivity. The gold nanoparticles will be used as a reporting agent enabling a colorimetric identification of different biomarkers that may be present in nanosamples taken from artworks, providing a unique opportunity to immediately explore the origin of the binders at the naked eye. The NANOART kit will hopefully be made available to conservation scientists from around the world, facilitating the knowledge over historical productions and help worldwide museums, conservation and restoration art studios and laboratories to plan the best conservation and preventive strategies for our worldwide Cultural Heritage.";166336,2;166336,2;FP7-PEOPLE-2012-IEF;/MC-IEF;UNIVERSIDAD DE ZARAGOZA;ES;;;/SCI;1;0;0;1;0;0 94143;250117;TIMESIGNAL;ONG;FP7-IDEAS-ERC;ERC-AG-LS1;FP7;Signalling within the mammalian circadian timing system;2010-04-01;2015-12-31;;The main objective of this interdisciplinary research project is to elucidate regulatory mechanisms through which the circadian timing system coordinates temporal physiology. This system has a hierarchical architecture, in that a master clock in the brain s suprachiasmatic nucleus synchronizes subsidiary oscillators in nearly all body cells. The establishment of phase coherence is obviously of utmost importance in the coordination of circadian physiology. While recent studies have identified feeding cycles, hormone rhythms, and body temperature oscillations as timing cues for peripheral clocks, the molecular makeup of the involved signalling mechanisms is largely unknown. Using liver and cultured cells as model systems, we will employ two innovative strategies for the elucidation of relevant signalling pathways. (1) STAR-Prom (Synthetic TAndem Repeat-PROmoter display), a technique developed in our laboratory, will hopefully identify most if not all immediate early transcription factors activated in cultured cells by rhythmic blood-borne and temperature-dependent signals. (2) A transgenic mouse model with conditionally active liver clocks will be explored in the genome-wide identification of coding and non-coding transcripts whose rhythmic accumulation is system-driven. The in vivo significance of the components emerging from these approaches will be assessed via RNA interference. Thus, relevant siRNAs will be injected into the tail vein of mice, and their effect on the phase of circadian liver gene expression will be monitored in freely moving mice by using whole body fluorescence imaging. Physiologically important components will serve as entry points for the identification of upstream and downstream constituents in the corresponding signal transduction cascades.;2360136;2360136;ERC-2009-AdG;/ERC-AG;UNIVERSITE DE GENEVE;CH;;;"/BIO;/LIF";1;0;0;1;0;0 94364;249869;DARCGENS;ONG;FP7-IDEAS-ERC;ERC-AG-LS2;FP7;Derived and Ancestral RNAs: Comparative Genomics and Evolution of ncRNAs;2010-05-01;2015-04-30;;Much light has been shed on the number, mechanisms and functions of protein-coding genes in the human genome. In comparison, we know almost nothing about the origins and mechanisms of the functional dark matter , including sequence that is transcribed outside of protein-coding gene loci. This interdisciplinary proposal will capitalize on new theoretical and experimental opportunities to establish the extent by which long non-coding RNAs contribute to mammalian and fruit fly biology. Since 2001, the Ponting group has pioneered the comparative analysis of protein-coding genes across the amniotes and Drosophilids within many international genome sequencing consortia. This Advanced Grant will break new ground by applying these approaches to long intergenic non-coding RNA (lincRNA) genes from mammals to birds and to flies. The Grant will allow Ponting to free himself of the constraints normally associated with in silico analyses by analysing lincRNAs in vitro and in vivo. The integration of computational and experimental approaches for lincRNAs from across the metazoan tree provides a powerful new toolkit for elucidating the origins and biological roles of these enigmatic molecules. Catalogues of lincRNA loci will be built for human, mouse, fruit fly, zebrafinch, chicken and Aplysia by exploiting data from next-generation sequencing technologies. This will immediately provide a new perspective on how these loci arise, evolve and function, including whether their orthologues are apparent across diverse species. Using new evidence that lincRNA loci act in cis with neighbouring protein-coding loci, we will determine lincRNA mechanisms and will establish the consequences of lincRNA knock-down, knock-out and over-expression in mouse, chick and fruitfly.;2400000;2400000;ERC-2009-AdG;/ERC-AG;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;UK;MEDICAL RESEARCH COUNCIL;UK;"/BIO;/LIF";1;0;0;1;0;0 105149;316959;DoHip;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-ITN;FP7;Training Program for the Design of Resource and Energy Efficient Products by High Pressure Processes;2013-02-01;2017-01-31;;"Aim of the Training Program (DoHip) is to meet the growing demand of Europe’s industry for highly trained scientists and engineers in process technology. Process Technology is fundamental for chemical, pharmaceutical, and polymer industry as well as food industry and cosmetics. High Pressure Processes like the Polyethylene Synthesis have been developed in Europe, leading to the outstanding position of European industries. Today’s demand on industry is to develop sustainable products and processes. High Pressure Technology can provide the answer. In the training network knowledge on the unique possibilities of high pressure is generated. New technologies and biobased products like leather from pressure supported tanning, free of waste water containing chromium, are developed and demonstrated in science and industry. For designing new, innovative and sustainable products and processes interdisciplinary project teams will work hand in hand. This is reflected in the consortium, comprising chemical and mechanical engineers as well as natural scientists. Five leading European universities with proven records in high pressure technology (Bochum, Budapest, Graz, Maribor and Valladolid) together with one Fraunhofer institute and one SME are forming the core of DoHip. They are supported by 8 companies from 7 European countries ranging from SMEs to global players. Each partner has complementary expertise and equipment which will be combined, resulting in a unique training program. Besides the highly sophisticated training through research in high pressure technology training on complementary skills (e.g. IP, presentation skills, project management, entrepreneurship, scientific writing) will be provided. Each ESR will absolve an internship at an associated industrial partner to improve job opportunities. Researchers educated in former RTN programs are taking over mentorship for the DoHip ESRs, introducing them into the existing high pressure network across Europe.";2970954;2970954;FP7-PEOPLE-2012-ITN;/MC-ITN;RUHR-UNIVERSITAET BOCHUM;DE;"TECHNISCHE UNIVERSITAET GRAZ;UNIVERSIDAD DE VALLADOLID;RUBOTHERM GMBH;FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.;BUDAPESTI MUSZAKI ES GAZDASAGTUDOMANYI EGYETEM;UNIVERZA V MARIBORU";"AT;ES;DE;HU;SI";/LIF;1;0;0;1;0;0 105878;308115;VISUAL-MS;ONG;FP7-IDEAS-ERC;ERC-SG-PE4;FP7;"Visualising Supramolecular Assembly by preparative Mass Spectrometry";2013-01-01;2017-12-31;;'The aim of VISUAL-MS is to investigate the structure and the assembly of individual functional adsorbed molecules with sub-nm resolution. This is an essential and still missing step in the development of a molecular scale foundation of many contemporary research fields. In order to achieve these goals, ultra high resolution scanning probe microscopy techniques are needed. However, these require that complex molecular units are deposited onto well-defined substrates under perfectly controlled conditions and that they are analysed in-situ. This is beyond the current state-of-the-art. In fact, thermal sublimation in ultra high vacuum is the strategy of choice for small, heat-resistant molecules but big functional (bio)molecules are not compatible with this process. VISUAL-MS will address this challenge by adapting a technique developed in mass spectrometry for transferring intact fragile molecules into the gas phase and by combining this with in-situ scanning probe microscopy. This interdisciplinary approach will expand the boundaries of modern surface science by enabling to apply its powerful diagnostic techniques to almost any type of complex functional molecule. It represents an essential step change in analytical capability and will provide groundbreaking new insight into fundamental molecule-substrate interactions. VISUAL-MS will apply this innovative instrumentation to explore the adsorption, mutual interaction and real-time dynamics of peptides on surfaces. The planned experiments will allow to determine which functional groups in a peptide interact with a substrate of given structure and chemistry and to directly visualise, for the first time, the secondary structure of individual peptides with sub-molecular resolution. These breakthrough achievements will open new horizons in the basic understanding of molecule-surface interactions and serve as a reference in the formulation of rationale protocols for the fabrication of (bio)molecular functionalised substrates';1578211,2;1578211,2;ERC-2012-StG_20111012;/ERC-SG;THE UNIVERSITY OF WARWICK;UK;;;"/PSE;/MAT";1;0;0;1;0;0 95174;257004;HHNCDMIR;ONG;FP7-IDEAS-ERC;ERC-SG-PE1;FP7;Hochschild cohomology, non-commutative deformations and mirror symmetry;2010-10-01;2016-09-30;;'Our research programme addresses several interesting current issues in non-commutative algebraic geometry, and important links with symplectic geometry and algebraic topology. Non-commutative algebraic geometry is concerned with the study of algebraic objects in geometric ways. One of the basic philosophies is that, in analogy with (derived) categories of (quasi-)coherent sheaves over schemes and (derived) module categories, non-commutative spaces can be represented by suitable abelian or triangulated categories. This point of view has proven extremely useful in non-commutative algebra, algebraic geometry and more recently in string theory thanks to the Homological Mirror Symmetry conjecture. One of our main aims is to set up a deformation framework for non-commutative spaces represented by 'enhanced' triangulated categories, encompassing both the non-commutative schemes represented by derived abelian categories and the derived-affine spaces, represented by dg algebras. This framework should clarify and resolve some of the important problems known to exist in the deformation theory of derived-affine spaces. It should moreover be applicable to Fukaya-type categories, and yield a new way of proving and interpreting instances of 'deformed mirror symmetry'. This theory will be developed in interaction with concrete applications of the abelian deformation theory developed in our earlier work, and with the development of new decomposition and comparison techniques for Hochschild cohomology. By understanding the links between the different theories and fields of application, we aim to achieve an interdisciplinary understanding of non-commutative spaces using abelian and triangulated structures.';703080;703080;ERC-2010-StG_20091028;/ERC-SG;UNIVERSITEIT ANTWERPEN;BE;;;"/PSE;/MST";1;0;0;1;0;0 88852;223414;LEISHDRUG;ONG;FP7-HEALTH;HEALTH-2007-2.3.4-1;FP7;Targeting the Leishmania kinome for the development of novel anti-parasitic strategies;2008-10-01;2012-03-31;;Visceral leishmaniasis is caused by the protozoan parasites Leishmania donovani and Leishmania infantum and is a potentially fatal disease in endemic areas around the world. During the infectious cycle, Leishmania alternate between the insect promastigote stage and the vertebrate aflagellate amastigote stage that proliferates inside infected host macrophages provoking the pathology of the disease. This consortium uses a highly interdisciplinary approach to reveal Leishmania signaling molecules associated with amastigote virulence, with the major aim to exploit parasite-specific pathways for anti-leishmanial drug development. We use innovative drug screening concepts not applied previously on parasitic systems. We will utilize visual high-content screening to discover compounds capable to kill intracellular Leishmania amastigotes without deteriorating the host cell. This phenotype-based strategy relies on fluorescent parasites and macrophages as read-outs and will allow simultaneous assessment of anti-leishmanial activity and host cell toxicity under physiological conditions. We will apply a target-based strategy utilizing recombinant Leishmania protein kinases for inhibitor identification and structure-guided drug design. The identification of appropriate target kinases, with only limited homology to their mammalian counterparts will rely on in silico analysis by applying novel bioinformatic tools developed by consortium members, and in vitro assay based on their phospho-transferase activity towards recombinant Leishmania phospho-proteins. The major objectives of this proposal are (i) to screen small molecule and peptide libraries for hit compounds with leishmanicidal activity using phenotype- and target-based strategies, (ii) to identify anti-parasitic lead compounds and assess their pharmacokinetic profiles using cell-culture and experimental infection models for leishmaniasis, and (iii) to initiate lead optimization by structure-based drug design.;4491633;2852232;FP7-HEALTH-2007-B;/CP-SICA;INSTITUT PASTEUR;FR;"UNIVERSIDAD POMPEU FABRA;UNIVERSITA DEGLI STUDI DI ROMA TORVERGATA;INSTITUT PASTEUR DE TUNIS;IP RESEARCH CONSULTING SASU;INSTITUT PASTEUR DE MONTEVIDEO;INSTITUT PASTEUR KOREA;TECHNISCHE UNIVERSITAET BRAUNSCHWEIG;AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS;LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE;TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FUNDACIO CENTRE DE REGULACIO GENOMICA";"ES;IT;TN;FR;UY;KR;DE;UK;IL";"/MED;/MBI";1;0;0;1;0;0 99516;269616;DIVIDNORM;ONG;FP7-IDEAS-ERC;ERC-AG-SH4;FP7;Divided Metacognition: when epistemic norms conflict;2011-07-01;2016-12-31;;The present project aims to provide a naturalistic account of epistemic norms, and of the associated epistemic awareness in children and adults from different cultures. Epistemics norms (ENs) such as intelligibility, relevance, truth, coherence and consensus are dimensions on which mental contents can be evaluated for their contribution to knowledge acquisition. Although EN sensitivity is central in education, little is known about 1) how to systematically analyze and inventory ENs, nor about 2) How and to what extent, children and adults from different cultures and socioeconomic backgrounds recognize them in making epistemic decisions. Specialists in philosophy of mind, developmental and adult congitive science, along with field anthropology, will apply their methods to address these questions in an interdisciplinary spirit. A common methodological guideline will be to study EN sensitivity as embedded in self-evaluative judgments, and to focus on cases of conflict between various ENs, such as consensus versus truth. This research should reveal how EN sensitivity develops in European and Japanese children, what role is to be assigned, in norm dominance, to emotional interaction, epistemic or social deference, and how EN sensitivity is transferred, in similar tasks and contexts, from self to others and reciprocally.;2360136;2360136;ERC-2010-AdG_20100407;/ERC-AG;ECOLE NORMALE SUPERIEURE;FR;"LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN;FONDATION PIERRE-GILLES DE GENNES POUR LA RECHERCHE;UNIVERSITE DE NEUCHATEL";"DE;FR;CH";/MED;1;0;0;1;0;0 106898;312785;AgricUrb;ONG;FP7-IDEAS-ERC;ERC-SG-SH6;FP7;The Agricultural Origins of Urban Civilization;2013-02-01;2017-01-31;;The establishment of farming is a pivotal moment in human history, setting the stage for the emergence of class-based society and urbanization. Monolithic views of the nature and development of early agriculture, however, have prevented clear understanding of how exactly farming fuelled, shaped and sustained the emergence of complex societies. A breakthrough in archaeological approach is needed to determine the actual roles of farming in the emergence of social complexity. The methodology required must push beyond conventional interpretation of the most direct farming evidence – archaeobotanical remains of crops and associated arable weeds – to reconstruct not only what crops were grown, but also how, where and why farming was practised. Addressing these related aspects, in contexts ranging from early agricultural villages to some of the world’s earliest cities, would provide the key to unraveling the contribution of farming to the development of lasting social inequalities. The research proposed here takes a new interdisciplinary approach combining archaeobotany, plant stable isotope chemistry and functional plant ecology, building on groundwork laid in previous research by the applicant. These approaches will be applied to two relatively well researched areas, western Asia and Europe, where a series of sites that chart multiple pathways to early complex societies offer rich plant and other bioarchaeological assemblages. The proposed project will set a wholly new standard of insight into early farming and its relationship with early civilization, facilitating similar approaches in other parts of the world and the construction of comparative perspectives on the global significance of early agriculture in social development.;1199647;1199647;ERC-2012-StG_20111124;/ERC-SG;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;UK;;;"/SCI;/SOC";1;0;0;1;0;0 94483;239285;SOLUTION;;FP7-ENERGY;ENERGY.2008.8.4.1;FP7;Sustainable Oriented and Long-lasting Unique Team for energy self-suffIcient cOmmuNities;2009-11-06;2014-11-05;;"The SOLUTION project mobilises public / private resources to build showcases of energy self sufficient communities in Austria, Croatia, Finland and Switzerland (together with the associated Slovenian community) with a strong potential for replication throughout Europe. SOLUTION is designed to respond to the needs of an effective take-off of the European SET-plan by demonstrating novel applications of different energy technologies and techniques integrated in an intelligent way within model areas. Although the individual demonstration projects are independent from each other, being designed to fulfil local energy needs and using local resources, there are many similarities between them. The implementation plan is a mix of local and integrating activities, such as 1)sharing latest research results especially of electricity storage, customer behaviour and intelligent RES integration, 2)demonstrating appropriate energy solutions in order to reach self-sufficiency, 3)establishing adequate business environment favourable for CONCERTO demonstrations, 4)serving as benchmark for sustainable communities and spreading best-practice, 5)developing a transparent SOLUTION model for immediate replication. By deploying an interdisciplinary approach, an innovative / cost-efficient mix of actions, a set of sustainability oriented solutions will be pointed out and transferred to and among the identified target groups of SOLUTION. The outcomes and related benefits will be fully exploited by an effective range of actions generating local activities with high visibility character together with the major stakeholders. Thus the members of the consortium will act as forerunners towards the low carbon future. The consortium composition is a balanced mix of representative model areas ready for demonstration and of 17 communal, industrial and scientific European partners (incl. 6 SMEs) with a wide geographical spread, complementary resources and expertise. ";20560606,23;11235626,62;FP7-ENERGY-2008-TREN-1;/CP;PLANAIR SA;CH;"LAPUAN KAUPUNKI;Schneider Electric Buildings Finland Oy;KW Solartechnik Planungs-Entwicklungs-Produktions- und Vertriebs GmbH;Thermopolis Oy;Splitsko-dalmatinska županija;HEP-Obnovljivi izvori energije d.o.o. za proizvodnju elektriæne energije;Interessensgemeinschaft Passivhaus Steiermark / Burgenland;COMMUNE DE CERNIER;Schneider Electric Finland Oy;ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE;Ökoregion Kaindorf;IC CONSULENTEN ZIVILTECHNIKER GESMBH;STADTWERKE HARTBERG VERWALTUNGS GMBH;COMMUNE DE VAL-DE-RUZ;Contren SA;FH JOANNEUM GESELLSCHAFT MBH;TEKNOLOGIAN TUTKIMUSKESKUS VTT;AGENCIJA ZA PRESTRUKTURIRANJE ENERGETIKE DOO";"FI;AT;HR;CH;SI";/OET;1;0;0;1;0;0 99781;293713;FLEAMICROBIOME;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-CIG;FP7;Effects of ecological factors on bacterial communities of fleas;2011-09-01;2015-08-31;;RESEARCH PROBLEM: The identification of potential ecological factors that affect the dynamics between hosts, vectors, and their microbes could have a marked impact on our ability to prevent and control vector-borne diseases. Recent studies have suggested that interactions among microbes within the individual vector may affect the density of a pathogen, and its transmission rate and virulence to the host. However, factors that affect the microbial composition of vectors remain obscure. I will use a rodent–flea model to elucidate the effects of three candidate factors, host age and grooming behavior, and vector densities on a host, that are likely to impact microbial diversity of vectors. PROPOSED METHODOLOGY: Pyrosequencing—a recent developed technique in molecular biology—allows a comprehensive assessment of microbial communities. The current project will make use of this technique to compare between the microbial assembly of fleas that will be collected during a field survey from juvenile and adult rodents, and during two laboratory experiments, in which host grooming and flea densities will be manipulated. EXPECTED CONTRIBUTION: In this study, I will investigate the relationships between multiple functional groups, i.e., hosts, vectors, and their commensal, mutualistic, and parasitic microbes. This approach is expected to uncover key mechanisms that would not – and could not – be revealed by focusing on a single pathogen. The results of the study can also serve as a basis for assessing the local risk of transmission of flea-borne diseases to animals and people and predicting whether this risk will change in response to changes in flea densities, host behavior, and host-age distribution. The interdisciplinary basic and applied importance and timeliness of the research topic – together with the match between my profile and project –promise the success of this project and its contribution to European excellence and European competitiveness.;100000;100000;FP7-PEOPLE-2011-CIG;/MC-CIG;BEN-GURION UNIVERSITY OF THE NEGEV;IL;;;/SCI;1;0;0;1;0;0 95712;260875;NANOMECH;ONG;FP7-IDEAS-ERC;ERC-SG-LS3;FP7;Protein Friction of Molecular Machines: Nanomechanics with Optical Tweezers;2010-12-01;2015-11-30;;"Molecular machines---assemblies of macromolecules, often fueled by nucleotide hydrolysis---are fascinating devices and crucial for driving self-organization in cells. While protein components of many biological machines have been identified, and in many cases their structures have been solved, the mechanical principles that govern the operation of biological machines are poorly understood. For example, how much force can they generate; and what limits their speed and efficiency? These questions have been difficult to answer because the tools needed to study nanometer-sized machines that generate minute forces on the order of piconewtons have not been available until recently. Friction arises between proteins when they interact by making and breaking weak intermolecular bonds. When a bond breaks, the energy stored in its deformation is dissipated. Protein friction is a useful concept because it provides mechanical insight and allows for quantitative theoretical understanding of the dynamics and energy balance of mechanical cellular processes. In cells, many motor proteins often cooperate to drive motility. I will ask how friction and force-generation arise and scale with the number of motors to elucidate how collective behavior and self-organization emerge. The goals of this interdisciplinary project address the role that protein friction plays in limiting the dynamics and efficiency of microtubule-based motor proteins using a novel, combined optical tweezers and single-molecule fluorescence apparatus. In the long term, I hope that our avant-garde nanotechnological tools will be applicable to other molecular machines and that the studies on microtubule-based motors will shed light on the way that cells use energy to create pattern and order.";1500000;1500000;ERC-2010-StG_20091118;/ERC-SG;EBERHARD KARLS UNIVERSITAET TUEBINGEN;DE;TECHNISCHE UNIVERSITAET DRESDEN;DE;"/BIO;/LIF";1;0;0;1;0;0 95783;252713;BOI;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IEF;FP7;Body-Object Integration (BOI): The neurocognitive basis of integrating conceptual object knowledge in the body representation;2010-09-01;2012-08-31;;In our daily lives we often use objects that greatly expand our bodily action capabilities, such as writing with a pen, handling a mobile phone or driving a car. The overall aim of the present proposal is to elucidate the neurocognitive basis of how conceptual object knowledge is integrated in our body representation. We will develop an innovative experimental paradigm in which we manipulate the congruence of body-object relationships at both a distal level (e.g. placing a glove near the hand) and a proximal level (e.g. putting a backpack on the back). The experimental paradigm will quantify subjective, behavioral and neuroimaging measures to provide new insights into the functional and neural correlates of how conceptual object knowledge is incorporated in the body representation. The outcomes of the project will not only extend our knowledge about the human brain but will also be relevant for clinical purposes, e.g. with respect to learning to use prosthetic devices, developing brain-computer interfaces and robotics and introducing new medical products. The project will be conducted for two years in the lab of professor Olaf Blanke at the Brain Mind Institute at Lausanne, with state-of-the-art research facilities and an excellent reputation. The quality and excellence of the proposed research project are comprised by (1) the combination of my strong research background on object-directed actions with Olaf Blanke’s expertise on body representations, (2) the use of innovative research methods (3) the interdisciplinary nature of the project and (4) the challenging theoretical question on how long-term conceptual knowledge is integrated in our body representation. This project will allow me to greatly expand my theoretical and practical skills to become an independent researcher and it will foster collaboration between two of the top research institutes on cognitive neuroscience in Europe.;180970,8;180970,8;FP7-PEOPLE-2009-IEF;/MC-IEF;ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE;CH;;;"/SCI;/EDU;/ITT";1;0;0;1;0;0 98987;260822;DICIG;ONG;FP7-IDEAS-ERC;ERC-SG-LS2;FP7;Dynamic Interplay between Eukaryotic Chromosomes: Impact on Genome Stability;2011-06-01;2017-05-31;;The structure and role of the DNA molecule raise fascinating questions regarding its dynamics, i.e. not only the tri-dimensional reorganisation associated with functional events at short time-scale, but also the structural changes, i.e. rearrangements, that occur in the chromosome over generations. It is increasingly obvious that the physical properties of both the chromosomes and their environment the nucleoplasm, the nuclear periphery, cytoskeleton, etc. are playing important roles in the dynamic changes observed. For instance, we recently showed that chromosome movements during mid-prophase of meiosis in budding yeast result from a trans-acting force generated at the level of the global cytoskeleton network, suggesting that extranuclear mechanical trans-acting signals could also regulate chromosomal metabolism in other ways. Our objectives are to make important contributions to the understanding of the mechanical and functional interplay between the cytoskeleton, the nuclear periphery, and chromosomes through in vitro and in vivo interdisciplinary approaches. We will investigate three questions of fundamental importance: i) the potential transmission and function of mechanical forces from the cytoskeleton to chromatin during interphase, ii) the physical principles that govern chromosome reorganization under mechanical force in vitro, and iii) the global chromatin dynamics during the fundamental S phase and its impact on genome stability. We will use a combination of high-resolution imaging, micromanipulation, and high-throughput molecular techniques (chromosome conformation capture and ChIP-Seq) to reach our goals. Most of these studies will be performed in budding yeast, but will have repercussions in our understanding of higher eukaryotes metabolism.;1497000;1497000;ERC-2010-StG_20091118;/ERC-SG;INSTITUT PASTEUR;FR;;;"/BIO;/LIF";1;0;0;1;0;0 107721;330305;CHIRALCMR;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IIF;FP7;"Chiral catalytic membrane reactor for high efficient preparation of enantiopure compounds";2013-03-05;2015-03-04;;Chirality is a universal phenomenon in nature. Many pharmaceuticals, nutraceuticals, and agricultural chemicals have their own stereoisomers, with each enantiomer showing a unique biological activity. The production of pure enantiomer is therefore essential especially for medication safety and efficacy. In this project, a novel membrane reactor technique is proposed for efficient production of important chiral intermediates in the pharmaceutical industry and agrochemistry. New homochiral metal-organic framework (MOF) materials and membranes will be integrated with the latest development in ceramic hollow fibres, in an objective of generating a catalytic membrane reactor (CMR) coupling asymmetric synthesis and enantioselective separation into a single micro-tube. Such CMR to be developed is composed of a homochiral MOF membrane layer supported on a ceramic hollow fibre substrate with a unique dual-structure, i.e. a porous functional layer for preparing the MOF membrane and a finger-like layer where MOF-based asymmetric catalysts can be deposited. Reactants fed to the tube side of the hollow fibre substrate will be converted into desired enantiomer and by-products. Meanwhile, the desired enantiomer recognized by the MOF membrane materials coated on the exterior functional layer will adsorb on the membrane surface, followed by diffusing through the membrane for enantioselective separation, with the by-products rejected by the membrane and collected at the outlet. Such an original interdisciplinary approach of producing chiral intermediates involves the latest multidisciplinary knowledge and techniques in material, chemistry, membrane, chemical engineering and catalysis, and has not yet been attempted to date. Moreover, the successful delivery of this project allows possible assembling of such micro-tubular CMR into an industrial scale prototype device or system, for a larger scale production of chiral intermediates.;231283,2;231283,2;FP7-PEOPLE-2012-IIF;/MC-IIF;IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE;UK;;;/SCI;1;0;0;1;0;0 103758;300408;EMULSIFOOD;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IOF;FP7;EMULSION DESIGN TO IMPROVE NUTRITIONAL AND ORGANOLEPTIC QUALITY OF CEREAL BASED FOOD SYSTEMS;2013-01-15;2016-01-14;;In light of the alarming reports on (the evolution of) the health condition of consumers in the developed world, research and food industry environments are currently investing much time and effort in the quest for ‘healthier’ food systems. However, inclusion or in situ production of bioactive compounds in food systems to improve their nutritional profile while maintaining their organoleptic properties presents real challenges. While emulsions offer perspectives for improved food systems, conventional emulsions suffer from droplet coalescence, flocculation, gravitational separation and Ostwald ripening. The design of structured emulsions with an improved stability and tailor-made functionality has already proven to be a valuable strategy for enhancing the nutritional profile and overall product quality of ‘liquid’ food systems as exemplified by protection and controlled release of bioactive and functional agents during processing. However, such approach needs to be elaborated on for complex 'dry' cereal based food systems. This project thus focuses on rational design of structured emulsions as functional carrier systems for application in such products, which include bread as an important staple food. The project will benefit from interdisciplinary collaboration between the research groups of Prof. J.A. Delcour (K.U.Leuven, Belgium) and Prof. D.J. McClements (University of Massachusetts, Amherst, USA), two highly renown researchers in their respective research areas.;267551,4;267551,4;FP7-PEOPLE-2011-IOF;/MC-IOF;KATHOLIEKE UNIVERSITEIT LEUVEN;BE;;;/SCI;1;0;0;1;0;0 110474;328102;FRAWM;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IOF;FP7;"Feeding the roman army in the western Maghreb. Multidisciplinary approach for the study of the army's grain supply in the southern limit of the Roman Empire (province of Mauretania Tingitana)";2014-02-20;2017-02-19;;'The proposed research concerns a multidisciplinary study of problem of military grain supply and the role of the army in the Roman province of Mauretania Tingitana (present day Morocco) starting from the identification of the storage buildings in the military camps. In order to gain new knowledge of this complex cultural and political context, the study will be carried out in an interdisciplinary approach. A combination of archaeological, geological, geophysical methods and remote sensing with archaeobotany, epigraphical texts, and Roman history can help us identify the organisation of the the system of grain's supply. At the same time the storage buildings, compulsory requisition, taxation/tribute, staple diet and grain quality, the influence the army had on the local population and consequent changes in local economic and social patterns will be analysed. The Applicant proposes to carry out a three-year research: a two-year period at the 'Institut National des Sciences de l’Archéologie et du Patrimoine (I.N.S.A.P.)' (Outgoing Host Organisation) of Rabat (Morocco) and a one-year stay at the “Ecole francaise de Rome (EFR)” (Return Host Organisation). Collaboration with the 'Institut National des Sciences de l’Archéologie et du Patrimoine' guarantees the possibility to develop a real laboratory-based activity for the direct examination of military camps in the province. The results of the spatial analysis will give new information about the distribution and position of unknown warehouses and granaries, and will help further investigation in the field. This project will be of mutual benefit for the applicant and the return host organisation, and will enhance EU scientific excellence through new agreements with North African institutions for new fieldwork projects. Dissemination of results by scientific publications and organisation of a workshop will stimulate the creation of a researchers network working on the topic of this project in the Euro-Mediterranean area.';226989,6;226989,6;FP7-PEOPLE-2012-IOF;/MC-IOF;ECOLE FRANCAISE DE ROME;IT;;;/LIF;1;0;0;1;0;0 101422;279100;BRIDGE;ONG;FP7-IDEAS-ERC;ERC-SG-PE8;FP7;"Biomimetic process design for tissue regeneration: from bench to bedside via in silico modelling";2011-12-01;2016-11-30;;"'Tissue engineering (TE), the interdisciplinary field combining biomedical and engineering sciences in the search for functional man-made organ replacements, has key issues with the quantity and quality of the generated products. Protocols followed in the lab are mainly trial and error based, requiring a huge amount of manual interventions and lacking clear early time-point quality criteria to guide the process. As a result, these processes are very hard to scale up to industrial production levels. BRIDGE aims to fortify the engineering aspects of the TE field by adding a higher level of understanding and control to the manufacturing process (MP) through the use of in silico models. BRIDGE will focus on the bone TE field to provide proof of concept for its in silico approach. The combination of the applicant's well-received published and ongoing work on a wide range of modelling tools in the bone field combined with the state-of-the-art experimental techniques present in the TE lab of the additional participant allows envisaging following innovation and impact: 1. proof-of-concept of the use of an in silico blue-print for the design and control of a robust modular TE MP; 2. model-derived optimised culture conditions for patient derived cell populations increasing modular robustness of in vitro chondrogenesis/endochondral ossification; 3. in silico identification of a limited set of in vitro biomarkers that is predictive of the in vivo outcome; 4. model-derived optimised culture conditions increasing quantity and quality of the in vivo outcome of the TE MP; 5. incorporation of congenital defects in the in silico MP design, constituting a further validation of BRIDGE’s in silico approach and a necessary step towards personalised medical care. We believe that the systematic – and unprecedented – integration of (bone) TE and mathematical modelling, as proposed in BRIDGE, is required to come to a rationalized, engineering approach to design and control bone TE MPs.'";1191440;1191440;ERC-2011-StG_20101014;/ERC-SG;UNIVERSITE DE LIEGE;BE;KATHOLIEKE UNIVERSITEIT LEUVEN;BE;"/PSE;/EAR";1;0;0;1;0;0 102000;280829;SHEV;ONG;FP7-IDEAS-ERC;ERC-SG-LS6;FP7;Stabilizing the exposure of neutralization epitopes on HIV-1 envelope glycoprotein trimer vaccines;2012-01-01;2016-12-31;;The impact of HIV/AIDS on world healthcare is tremendous, particularly in the Third World. To curtail the HIV epidemic a cheap and effective vaccine is urgently needed, but despite massive research efforts no vaccine is available yet. Although most vaccines work by inducing neutralizing antibodies, HIV has evolved many ways to limit the induction and binding of neutralizing antibodies. The challenge is to engineer Env subunit vaccines that do induce neutralizing antibodies efficiently. One aspect that has been highly underappreciated is conformational heterogeneity of Env. Conformational flexibility is exerted at three different levels. First, flexible variable loops and N-glycans protruding from the conserved protein core cause “local flexibility” at the protein surface. Second, movement between the conserved inner and outer domain of gp120 causes “tertiary flexibility”. Third, movement of the three gp120 protomers in the trimeric complex, resembling a flower that opens and closes, causes “quaternary flexibility”. These three levels of flexibility provide very unstable targets for recognition by low affinity B cell receptors on na?ve B cells, diminishing the chance of efficient B cell activation and the secretion of neutralizing antibodies. Using a number of novel structure-based vaccine design strategies that include the introduction of stabilizing disulfide bonds, we intend to remove the undesirable flexibility on Env trimers to provide a homogeneous and stable target to B cells. This should result in stabilized Env immunogens that are better in inducing neutralizing antibodies compared to the current state-of-the art Env vaccines. This is a highly interdisciplinary project on the crossroads of immunology and protein chemistry and should result in protein immunogens that elicit improved neutralizing antibody responses against HIV and should provide answers to fundamental questions on how B cells “see” protein immunogens.;1499943;1499943;ERC-2011-StG_20101109;/ERC-SG;Academisch Medisch Centrum bij de Universiteit van Amsterdam;NL;;;"/BIO;/LIF;/MED";1;0;0;1;0;0 110243;611288;COBRA;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IRSES;FP7;Cognition and Brains of Ecological Invaders;2013-08-15;2015-09-14;;The goals of this proposal are to 1. Lay down the building blocks for a long-term mutually beneficial collaborative research program examining the causes and consequences of species adaptation to environmental change between Prof Bugnyar (U Vienna), Dr Healy (U St Andrews), Prof Güntürkün (Ruhr-U Bochum), and Dr Griffin (U Newcastle, AUS), 2. Create a synergistic team of three experienced scientists (Dr Griffin, Dr Bailey, Dr Schwab) and three world-leading researchers in avian cognition, behaviour, and neuroscience (Bugnyar, Healy, Güntürkün) that will exchange research expertise and pool research facilities to undertake the first geographically global exploration of the role of behavioural flexibility and brain anatomy in species adaptation to rampant worldwide urbanization, and 3. Position three exchange researchers (Griffin, Bailey, Schwab) as interdisciplinary experts capable of working at the interface between behaviour, neuroscience and urban ecology. We propose a program of studies and researcher exchanges to investigate the behaviour and brains of three highly successful invasive avian species across a rural to urban environmental gradient. We seek funding for secondments of two outgoing European researchers, and one incoming Australian researcher to collect scientific data on avian species local to the area, learn new skill sets, and build collaborative links by participating in ongoing collegial exchange and national conferences. By examining several avian species, in several planet-wide geographical locations, using several different measures of behavioural flexibility, and describing associated brain changes, we will gain the first firm evidence for, or against, the hypothesis that increasing behavioural flexibility and enlarged brain size predispose animals to surviving on an increasingly urbanized planet. The program will achieve knowledge transfer between research partners, and create new knowledge of significant theoretical and applied importance.;25200;25200;FP7-PEOPLE-2013-IRSES;/MC-IRSES;UNIVERSITAT WIEN;AT;"THE UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS;RUHR-UNIVERSITAET BOCHUM";"UK;DE";/LIF;1;0;0;1;0;0 94409;249835;TERNANOMED;ONG;FP7-IDEAS-ERC;ERC-AG-LS7;FP7;TERPENOYLATION: AN ORIGINAL CONCEPT FOR THE DISCOVERY OF NEW NANOMEDICINES;2010-06-01;2015-05-31;;Terpenoids are a group of natural compounds that are extraordinary diverse in chemistry, structure and function. Most of the natural terpenoids are flexible and biocompatible biopolymers, having physico-chemical characteristics able to adapt to a wide variety of biologically active compounds. Surprisingly, they have never been used previously in the nanotechnology field for drug delivery and targeting purposes, except very recently by us to design squalene-based nanoassemblies. Thus, the current project aims to develop terpenoid-based nanoassemblies to improve the treatment of severe diseases incl. cancer, infectious and metabolic diseases. The conceptual approach is to chemically link a terpenoid to a biologically active drug molecule in order to allow the resulting bioconjugate to self-assemble as nanoparticles in water. Noteworthy, the nature of the polyterpenoid (ie. number of isoprenoid units) may be adapted to the hydrophilic/lipophilic character of the drug molecule to be transported, whereas the nature of the linkage (ester, amide, disulfide bonds etc.) will be selected according to the enzymatic content of the targeted diseased area. From the ratio between drug s and polyterpene s molecular weights, it is deduced that the drug loading will be dramatically improved as compared to the currently available nanomedicines. In other words, the pro-drug will form the nanomedicine by selfaggregation without the need of any other transporter material. The project will involve the following interdisciplinary aspects:(i) synthesis of drug/polyterpene bioconjugates,(ii)design of the nanoassemblies and their functionalization with recognition ligands,(iii)cell and tissue imaging and(iv)pharmacological evaluation in vitro (cell culture) and in vivo. Such ambitious and challenging project will be performed under Patrick Couvreur s leadership who has settled up a worldwide recognized multidisciplinary research team, unique in the nanomedicine world.;2198799;2198799;ERC-2009-AdG;/ERC-AG;UNIVERSITE PARIS-SUD;FR;"COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES;UNIVERSITE CATHOLIQUE DE LOUVAIN;BERTIN PHARMA";"FR;BE";"/HCS;/LIF;/MED";1;0;0;1;0;0 92696;235114;CLERMONT4;ONG;FP7-PEOPLE;FP7-PEOPLE-ITN-2008;FP7;Exciton-polaritons in microcavities: physics and devices;2009-09-01;2013-08-31;;"The discovery of Bose-Einstein condensation (BEC) of exciton-polaritons in 2006 and the demonstration of room-temperature polariton lasing in 2007 have opened the way to realisation of a new generation of optoelectronic devices referred to as polariton devices. The research on exciton-polaritons and polaritonics allows the quantum effects of superfluidity, entanglement, squeezing of light to be brought to the everyday life and used in new light sources, optical switches, modulators and memory elements. The fundamental principles of polariton physics have been established by our previous networks "CLERMONT" and "CLERMONT2" within the 5th and 6th FP. The breakthrough achieved in 2006-2007 brings the polaritonics on a new level and makes its rapid development in Europe an overall strategic priority. Our present consortium composed by 10 European academic teams and supported by 6 leading industrial groups has a critical mass in polariton physics and technology. We intend to form a new generation of solid state physicists able to maintain the European leadership in this rapidly developing interdisciplinary research field. Four of the present partners took part in the discovery of the BEC of polaritons and polariton lasing, six others have given key contributions into polaritonics over the last decade. The Coordinator of the project holds the Marie Curie Chair of Excellence "Polariton Devices" at the university of Rome. We propose 16 full term PhD and 3 postdoc projects to be realized at two network nodes each with a compulsary training in industry. We shall organize the international conference on Optics of Excitons in Confined Systems in 2009, 3 international conferences on Physics of Light-Matter Coupling in Nanostructures and 2 Summer Schools on Nanophotonics. The project will form a world-leading international team of researchers capable to implement the ideas of polaritonics in a new generation of optoelectronic devices.";4278121,76;4278121,76;FP7-PEOPLE-ITN-2008;/MC-ITN;UNIVERSITA DEGLI STUDI DI ROMA TORVERGATA;IT;"UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6;THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;THE UNIVERSITY OF SHEFFIELD;UNIVERSITY OF DURHAM;FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS;ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE;UNIVERSITY OF SOUTHAMPTON;UNIVERSIDAD AUTONOMA DE MADRID;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS";"FR;UK;EL;CH;ES";"/SCI;/EDU";1;0;0;1;0;0 99588;269322;PROSSALIC;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-IRSES;FP7;Product-Service System across Life Cycle;2011-07-01;2015-06-30;;"Nowadays, customers’ purchase habits have changed: they do not buy more goods or services in the traditional sense, perceiving them as two separated entities. They rather look for a solution, whose value encompasses many intertwined components, some of them being services and some being goods. In this context, the Product-Service System (PSS) concept finds its root. The servitization process of a product manufacturer into a provider of a PSS still constitutes a major managerial challenge. This challenge is based on a new kind of solution, which considers the continuum between services and products, where services represent a key element for gaining competitiveness. Theoretical and practical experiences show that servitization pushes organisations to change their strategies, operations and value chain, technologies, people expertise and system integration capabilities. As a consequence, different competences are requested to be analysed to have a complete vision of the PSS phenomenon. An international interdisciplinary working group is important to fulfil the need to provide a complete vision of the PSS. Due to the vastness of the area, it is relevant to bring together, in the context of a collaborative scheme of research exchanges, the reciprocal knowledge of the partners. The project proposal links 10 members: 4 EU, 2 AC, and 4 third country partners, which have agreed for a common exchange program on the analysis of the “Product-Service System across Life Cycle”. The exchange program aims to facilitate the deployment of a collaborative scheme focused on the exchange of the knowledge required to develop new models/methods/ICT tools to support the PSS across all its Life Cycle phases. Each member provides complementary knowledge on the field. The project will concern the exchange of a set of various activities of PhD students, researchers and professors. The planned exchange scheme will enable the reciprocal transfer of knowledge between the members.";239400;210000;FP7-PEOPLE-2010-IRSES;/MC-IRSES;UNIVERSITA' DEGLI STUDI DI BERGAMO;IT;"LULEA TEKNISKA UNIVERSITET;UNIVERSITA DEGLI STUDI DI FIRENZE;SHENKAR COLLEGE OF ENGINEERING AND DESIGN LTD;ORT BRAUDE COLLEGE;CRANFIELD UNIVERSITY;AALBORG UNIVERSITET";"SE;IT;IL;UK;DK";"/EMP;/SOC";1;0;0;1;0;0 90066;230331;PROPEREMO;ONG;FP7-IDEAS-ERC;ERC-AG-SH4;FP7;Production and perception of emotion: An affective sciences approach;2009-03-01;2015-02-28;;Emotion is a prime example of the complexity of human mind and behaviour, a psychobiological mechanism shaped by language and culture, which has puzzled scholars in the humanities and social sciences over the centuries. In an effort to reconcile conflicting theoretical traditions, we advocate a componential approach which treats event appraisal, motivational shifts, physiological responses, motor expression, and subjective feeling as dynamically interrelated and integrated components during emotion episodes. Using a prediction-generating theoretical model, we will address both production (elicitation and reaction patterns) and perception (observer inference of emotion from expressive cues). Key issues are the cognitive architecture and mental chronometry of appraisal, neurophysiological structures of relevance and valence detection, the emergence of conscious feelings due to the synchronization of brain/body systems, the generating mechanism for motor expression, the dimensionality of affective space, and the role of embodiment and empathy in perceiving and interpreting emotional expressions. Using multiple paradigms in laboratory, game, simulation, virtual reality, and field settings, we will critically test theory-driven hypotheses by examining brain structures and circuits (via neuroimagery), behaviour (via monitoring decisions and actions), psychophysiological responses (via electrographic recording), facial, vocal, and bodily expressions (via micro-coding and image processing), and conscious feeling (via advanced self-report procedures). In this endeavour, we benefit from extensive research experience, access to outstanding infrastructure, advanced analysis and synthesis methods, validated experimental paradigms as well as, most importantly, from the joint competence of an interdisciplinary affective science group involving philosophers, linguists, psychologists, neuroscientists, behavioural economists, anthropologists, and computer scientists.;2371331;2371331;ERC-2008-AdG;/ERC-AG;UNIVERSITE DE GENEVE;CH;"TECHNISCHE UNIVERSITAET MUENCHEN;FREIE UNIVERSITAET BERLIN";DE;/MED;1;0;0;1;0;0 107687;330946;NANO-FCSC;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IEF;FP7;Engineering of Nanocomposites for a New Energy Conversion Device Joining Fuel Cell and Solar Cell;2013-05-01;2016-03-14;;The overall aim of the Nano-FCSC project is to develop and engineer functional nanocomposite materials for a novel energy conversion technology, which combines the principle of both fuel cell and solar cell, and investigate scientific principles and device mechanisms, including ion and electron transport. Targets of the project are strongly innovative methodologies for the preparation, characterization, testing of advanced nanocomposite materials for joint fuel cell and solar cell device. This project is a multidisciplinary and interdisciplinary research encompassing nanotechnology, materials synthesis, materials characterization, thin film fabrication, device fabrication and performance test (fuel cell and solar cell) and modelling activities. Therefore, the experienced researcher will have exposure to a wide range of experts on nanoscience, fuel cell, solar cell, applied physics and modelling during the whole course of project development. Besides, Nano-FCSC project will generate new fundamental knowledge and foster new prospects and frontiers in the field of fuel cell, solar cell and nanotechnology.;207613,2;207613,2;FP7-PEOPLE-2012-IEF;/MC-IEF;AALTO KORKEAKOULUSAATIO SR;FI;;;/SCI;1;0;0;1;0;0 108360;331421;SAST;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IEF;FP7;Social Anchoring in Superdiverse Transnational Social Spaces;2013-09-02;2015-09-01;;"The project studies in an innovative, interdisciplinary theoretical and methodological way the problem of identity, integration and adaptation to transnational spaces. It aims to examine the role of identity for immigrant adaptation and integration and ways in which individuals, especially migrants, establish footholds in their life spaces. The goal of the proposal is the development of a theoretical and methodological framework that enables identification of the source(s) of socio-psychological stability of individuals, particularly in a context of societal integration. The researched problem will be analysed using the concept of social anchoring proposed by the author, which will be developed through research with Polish immigrants in the UK and Ukrainian immigrants in Poland. The research approach will be based on grounded theory. The project will include alternate stages of field research and theory building. The methods used in the project will include: desk research and analysis of secondary data, field research among Polish and Ukrainian immigrants in the UK and Poland and the analysis of “unguided” materials (i.e. forum discussions, web blogs and diaries), which will be analysed using narrative, biographical, textual and visual approaches as well as the analysis of observation material. The originality of the project lies in the idea of using the metaphor of anchor to develop the conceptual framework of anchoring enabling limitations of subjectively defined identity to be overcome whilst including the objective aspects of resources. The intensive inclusion of participants’ perspective and the employment of a reflective approach also add to the originally of the project. The theory of social anchoring will bring an entirely new approach to migration studies and provide an opportunity to link integration and identity problems and as well as relate individuals to a contemporary superdiverse and mobile society.";309235,2;309235,2;FP7-PEOPLE-2012-IEF;/MC-IEF;THE UNIVERSITY OF BIRMINGHAM;UK;;;/SCI;1;0;0;1;0;0 98350;277061;EXCOMMOD IBP;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-RG;FP7;A HOLISTIC EXERGETIC MODEL OF THERMAL COMFORT INCLUDING THE INDIVIDUAL THERMAL BACKGROUND AND PRODUCTIVITY OF AN OFFICE WORKER IN SUMMERTIME;2011-04-01;2015-05-31;;This research project aims at the development of a new holistic model of thermal comfort and productivity in the office environment by implementing the thermal background and behavioural actions of an individual human being and considering the human-body exergy-consumption rate. The focus will be on summer conditions and the expected results are a theoretical model together with algorithms to be used for simulation purposes. The objectives of this proposal will be reached by an interdisciplinary approach, i.e. by a strong cooperation with researchers with experience in studies on occupant behaviour as well as health and psychological aspects of thermal comfort. Furthermore, this project will be conducted in close cooperation with scientists from the former Japanese host due to their deep experience and knowledge in exergy analysis. With regard to the methodology applied, the objective will be reached by human data collection of physiological and behavioural reactions to distinctive thermal conditions together with the perceived thermal comfort in climate chamber experiments as well as field studies. A detailed understanding and the ability to predict the expected thermal comfort and productivity of an office worker together with the energy used for an existing or projected building must be crucial for a higher quality of life for the office worker, reduced costs for the entrepreneur and a reduced energy demand and CO2-emissions from the building sector. In addition, this will lead to further technological and conceptual advancements within the construction industry and the architectural and interior design field. Therefore, this project will result in a higher satisfaction of EU office workers, an increased productivity of EU based companies, while achieving the set goals for CO2-emission reduction more easily. Furthermore, this project facilitates the researcher the reintegration and increase the chances to start a successful research career in the EU.;97916,67;97916,67;FP7-PEOPLE-2010-RG;/MC-IRG;KARLSRUHER INSTITUT FUER TECHNOLOGIE;DE;;;/SCI;1;0;0;1;0;0 108484;326501;ASTEX;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IEF;FP7;Assyrian Textiles: A Study on the Terminology and the Material Culture of the Textiles in the Neo-Assyrian Empire;2013-04-26;2015-04-25;;The project, framed in the research programme Textile Terminologies 1000 BC to AD 1000 of the Centre for Textile Research, will catalogue and investigate the textile terminology in use in the Neo-Assyrian period (first millennium BC). The research is intended to give the scholars of both Oriental studies and of ancient textile studies a comprehensive study on the Assyrian textiles seen as historical sources to understand the organization of economy, the culture, and the society of the first world empire in history, thus challenging the dialogue of specialists of different historical periods and areas of the Ancient World about the textile terminology and the role of textiles in the development of economies and societies as well as in shaping realities through aesthetical and ideological conceptualization. In the past twenty years, the publication of a major part of the Assyrian texts in updated scientific editions provided a comprehensive evidence of a large set of lexical data concerning various types of goods. An accurate explanation of the semantics of many designations of material culture, however, is still a desideratum. This research is aimed at bridging this gap in the studies on the Akkadian textile terminology of the first millennium BC, publishing a still missing complete study of the Neo-Assyrian textiles. More importantly, it will be based on an interdisciplinary approach on the topic. Textiles represent important historical sources for the understanding of a given civilization. Accordingly, their designations in ancient texts must be analysed in a closer comparison with the representations of textile products in the visual art and in the archaeological evidence. Moreover, this project will also explore the possibility to use ethnographical evidence about production, decoration, and aesthetics of textiles in traditional communities of Middle Eastern countries in historical research on ancient textiles.;298932,6;298932,6;FP7-PEOPLE-2012-IEF;/MC-IEF;KOBENHAVNS UNIVERSITET;DK;;;/SCI;1;0;0;1;0;0 102005;283959;PRIMARCH;ONG;FP7-IDEAS-ERC;ERC-SG-SH6;FP7;Primate archaeology: an evolutionary context for the emergence of technology;2012-01-01;2017-04-30;;"Technology is essential to human survival, prompting the fundamental question of why we are the only species ever to have evolved complete reliance on tool use. The Primate Archaeology project examines the evolution of tool use for three wild non-human primate species - chimpanzees (Pan troglodytes), bearded capuchins (Cebus libidinosus), and long-tailed macaques (Macaca fascicularis aurea) - in order to place the extraordinary degree of tool use seen in the human lineage into a multi-species comparative context for the first time. These three species are the only primates known to use stone tools in the wild, resulting in long-term archaeological survival of their behavioural residues. Each of our inter-related research aims represents a new approach to the analysis of non-human tool use behaviour, including: 1. Standardised documentation of the technological signatures of multiple wild non-human primate species; 2. Recording the spatial (from site to landscape) and chronological patterns of primate tool use; and 3. Developing a comprehensive theoretical framework for inter-species technological comparisons. A team based at Oxford University will accomplish these aims over a five-year period, in collaboration with leading primatologists worldwide who have partnered with us to provide access to major field sites. This interdisciplinary project provides the first comparative data on the evolution of non-human technology, and involves a significant re-definition of archaeology to include the behavioural evidence of non-human animals. These data are necessary to test new hypotheses about human technological evolution, including the use of pounding technology by early humans, and the role of non-human primate behaviour in constructing models of hominin behaviour. These primate species and their tool use traditions are under imminent threat of extinction, and the opportunity to collect such data will likely be lost within a few decades.";1454310;1454310;ERC-2011-StG_20101124;/ERC-SG;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;UK;;;"/SCI;/SOC";1;0;0;1;0;0 109679;618333;COMPFLIX;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-CIG;FP7;Complex Fluid Interfaces in Biomedical and Industrial Multiphase Flows;2013-09-01;2017-08-31;;'The focus of my research is on interfacial fluid dynamics in complex multiphase flows. Fluid interfaces in biomedical flows and industrial processing flows present complex microstructures due to adsorption of surfactants or solid particles. The interfacial rheological properties of these complex fluid interfaces are crucial parameters for implementing predictive models of complex multiphase flows. Yet, current methods of interfacial fluid dynamics are limited to quasi-static deformations, which are not a realistic approximation of highly dynamic phenomena such as industrial mixing, aerobreakup, and drop breakup in turbulent flow. At the same time, the microstructural details of the interface that crucially determine the rheological response (e.g. phase separation, percolation, buckling) are inherently difficult to probe, and even more challenging to observe in dynamic interfaces. The overarching goal of my research program is to improve our understanding of complex fluid interfaces by precisely measuring the macroscopic mechanical properties and simultaneously probing the details of the interfacial microstructure in highly dynamic settings currently inaccessible to experiment. My experimental approach relies strongly on my interdisciplinary background in Physics and Engineering, which has taught me to combine multiple techniques to provide precise, direct, dynamic measurements. I will use a combination of high-speed microscopy, ultrafast acoustic excitation, fluidics and advanced optical methods to derive new insights in physico-chemical phenomena and continuum-scale mechanics of interfaces in multiphase flows. The proposed research will provide a new level of understanding of the dynamics of three classes of complex fluid interfaces, namely, lipid monolayers, particle monolayers, and lipid bilayers. This understanding will have a direct impact on the control and optimization of industrial processing flows and biomedical flows for medical imaging and drug delivery.';100000;100000;FP7-PEOPLE-2013-CIG;/MC-CIG;IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE;UK;;;/LIF;1;0;0;1;0;0 107675;327630;RETHINKING;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IEF;FP7;Rethinking uncertainty: A problem-based approach;2013-09-02;2015-09-01;;"The overarching aim of this research project is to improve our understanding of uncertainty, the robustness of its formal modelling and its inter-sectoral communication. Decision-making in the face of the continuing financial crisis and climate change policy-making are two problems of high socio-economic impact in which our overall understanding of uncertainty plays an unquestionably decisive role. This interdisciplinary project sets out to contribute to such pressing issues by addressing a set of key epistemological questions that arise in the construction of formal models of rational decision-making under uncertainty. By doing so it will throw new light on one of the most fundamental problems in the multifaceted field of uncertain reasoning: how to identify an efficient trade-off between foundational robustness and expressive power in the quantification of uncertainty. The expected results will bring foundational and methodological clarity as well as formal advance. The former will give rise to a novel framework in which a plurality of models of uncertain reasoning are developed in continuity with their intended applications in individual, social and institutional decision-making. As to formal advance, it is hoped that the new framework will lead to principled extensions of probabilistic measures of uncertainty and the maximisation of expected utility. Logic, decision theory and formal epistemology will provide the methods and techniques of investigation. The expected results will impact directly on economic theory, the foundations of probability and statistical inference, and artificial intelligence. The fulfilment of the research and training goals of the project will greatly benefit from the engagement with professionals and policy groups. This, in turn, is expected to add significantly to the project's impact outside the academia.";221606,4;221606,4;FP7-PEOPLE-2012-IEF;/MC-IEF;LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE;UK;;;/SCI;1;0;0;1;0;0 109280;607411;EREAN;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-ITN;FP7;European Rare Earth Magnet Recycling Network;2013-09-01;2017-08-31;;'Because China dominates the rare-earth market and is reducing its export quota, there is a very high supply risk for rare earths in Europe. To tackle this rare-earth crisis, Europe needs to invest in primary mining, substitution and, in particular, urban mining/recycling. To date, less than 1% of the rare earths are being recycled, due to, amongst others, a lack of efficient recycling technologies. The creation of a rare-earth recycling industry in Europe urgently requires an “army” of skilled chemists and engineers, who can tackle the barriers to develop fully closed-loop environmentally-friendly recycling flow sheets. EREAN will train 15 young researchers (12 ESR \ 3 ER) in the S/T of rare earths, with emphasis on the recycling of these elements from permanent magnets. An intensive intersectoral and interdisciplinary collaboration has been established in the EREAN consortium, which covers the full materials loop, from urban mine to magnet. EREAN will bundle European expertise in a cluster of excellence. Research challenges include the development of efficient extraction of rare-earth-containing materials from electronic waste scrap, removal of exogen elements (Fe, Ni, B) by pyro/hydrometallurgical methods to produce a concentrate of rare earths, new separation methods, direct electrochemical reduction of rare-earth oxides into metals, and the preparation of new magnets. By training the researchers in basic and applied rare-earth sciences, with emphasis on extraction and separation methods and rare-earth metallurgy, sustainable materials management, recycling methods, life cycle assessment (LCA), and the principles of urban mining, they will become the much needed “rare earthers” for employment in the growing European rare-earth industry. Concurrently, they will receive training in a multitude of soft skills, increasing their employability in the materials recycling and metallurgical industries.';3901642,14;3901642,14;FP7-PEOPLE-2013-ITN;/MC-ITN;KATHOLIEKE UNIVERSITEIT LEUVEN;BE;"HELSINGIN YLIOPISTO;FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.;THE UNIVERSITY OF BIRMINGHAM;RHODIA OPERATIONS;UMICORE;OEKO-INSTITUT E.V. - INSTITUT FUER ANGEWANDTE OEKOLOGIE;TECHNISCHE UNIVERSITEIT DELFT;CHALMERS TEKNISKA HOEGSKOLA AB";"FI;DE;UK;FR;BE;NL;SE";/LIF;1;0;0;1;0;0 109708;609024;SMART-ACTION;CLO;FP7-ICT;ICT-2013.1.4;FP7;SMART-ACTION;2013-09-01;2015-10-31;;With the increasing miniaturization of communication devices and the proliferation of technologies such as smart phones or sensor networks, the concept of an Internet of Things (IoT) is becoming a reality, especially with their integration into Smart Cities.
The interdisciplinary nature of IoT work requires understanding, coordinating, supporting and engaging not only ICT, but also other areas such as biotechnology or nanotechnologies, that provide the right context in which IoT concepts can be embedded to provide solutions that can benefit society at large.
SMART-ACTION will support the development of strategic research agendas and serve as an enabler for the dissemination and further integration of results into future research and industrial developments, while coordinating international efforts.
The main objective of SMART-ACTION is to provide support for International Road Mapping of the Research Agenda and Policies of IoT as part of the Future Internet Technological Development and to increase the uptake of European industry and businesses related to IoT, serving the Lisbon Agenda.
SMART-ACTION has several strategic goals:(i) To consolidate the current research and technology transfer activities in Europe and to make sure the efforts performed by individual research groups generate an optimal effect on others research areas.
(ii) To extend the reach of IoT technologies beyond Europe and to make sure that Asia, the US, Australia and Africa are all involved in the process of defining an overall strategy for the Internet of Things by providing input to workshops organised as part of SMART-ACTION.
(iii) To make sure that companies are also involved in the process to make sure that roadblocks and potential problems are identified and solved as early as possible. We will do this with a keen eye on IoT policy aspects that emerge in the context of a number of relevant policy areas by keeping track of these developments and highlighting IoT aspects that may need to be considered in those policy areas. Following this strategy, we are confident that paths for the transfer of technology and, in general, the creation of new business in areas related to the Internet of Things will be encouraged.;898200;750000;FP7-SMARTCITIES-2013;/CSA;UNIVERSITAET DUISBURG-ESSEN;DE;"STIFTELSEN SINTEF;GNKS CONSULT BV;EASY GLOBAL MARKET SAS";"NO;NL;FR";/INF;1;0;0;1;0;0 109588;608231;PROVISION;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-ITN;FP7;PeRceptually Optimised VIdeo compreSION;2013-09-01;2017-08-31;;"Around 50% of the human brain is dedicated to vision processing. This perhaps explains our capacity to be entertained, challenged and informed by visual information. Video technology is now pervasive, with mobile video, terrestrial and satellite HDTV, Blu-ray players, digital cameras, video telephony, multimedia messaging, video conferencing and surveillance all underpinned by efficient signal representations. It is therefore a very exciting and challenging time for video compression – the need for technical advances, and for the highly skilled researchers to deliver them, has never been greater! The main aim of PROVISION is to provide the highest level of training in video compression and transferable skills to our researcher team, with the ultimate goal of delivering transformational research, innovative technology and new international standards. Training activities will be conducted in the context of a high-level European research collaboration between some of the leading and most appropriate universities, research institutes, companies and end-user enterprises in Europe. The trained researchers will have significant competitive advantages in securing better jobs in academia or industry, and will be prepared as leaders in the development and uptake of this technology. Technical and management activities will be complemented by an integrated training programme. This will provide a broader scientific education for our team and will help to produce a new generation of researchers equipped with the interdisciplinary and transferrable skills needed by industry and academia. PROVISION’s training objectives will thus be delivered via: i) Permanent training of ESRs and ERs during their individual projects (supervised by two full partners and advised by one associated partner through internships), ii) knowledge-exchange through distributed shared platforms, iii) complementary schooling of ESRs and ERs through network activities and at specific training hubs.";4011661,06;4011661,06;FP7-PEOPLE-2013-ITN;/MC-ITN;FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.;DE;"RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN;BRITISH BROADCASTING CORPORATION;UNIVERSITY OF BRISTOL;UNIVERSITE DE NANTES";"DE;UK;FR";/LIF;1;0;0;1;0;0 109179;607142;DEVCOM;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-ITN;FP7;European Initial Training Network on Developmental and Computational Biology;2013-09-01;2017-08-31;http://www.devcom-itn.eu/;"The ability to manipulate cellular pluripotency and differentiation holds the as yet unrealized promise of regenerative medicine to produce replacement cells and tissues. To this end a deep understanding of the regulation of differentiation potential in the context of normal embryonic development is crucial. The recent revolution in sequencing technology has enabled high throughput and genome-wide analysis of cellular behaviour. The challenge with the new opportunities in genome-scale quantitative data gathering is to reach a more fundamental, systems level understanding of complex biological phenomena such as development and differentiation. The mission of the DevCom network is to train a new generation of promising scientists to bridge the gap between developmental and computational biology, and to prepare this generation for the emerging field of “New Biology” in which systems-level, quantitative and computational approaches are fully integrated in the analysis of profound scientific problems related to pluripotency and differentiation. The DevCom research plan revolves around early embryonic regulatory networks and disease networks in vertebrate embryos of the Xenopus and zebrafish model systems. The training plan involves interdisciplinary training with exposure to both academic and business settings. The trainees will acquire technical expertise in embryonic anatomy and development, genomic profiling, sequence conservation and evolutionary relationships of regulatory elements, genetic and chemical screens, mass spectrometry, informatics, statistics and computational modelling, and will be trained in a range of soft and complementary skills. Therefore the DevCom Training and Research Programmes are designed to foster readiness for leading roles in academia and industry and will have a lasting impact on the training programmes of participating institutions.";4015970;4015970;FP7-PEOPLE-2013-ITN;/MC-ITN;STICHTING KATHOLIEKE UNIVERSITEIT;NL;"UNIVERSITY OF EAST ANGLIA;UNIVERSIDAD PABLO DE OLAVIDE;QIAGEN AARHUS AS;THE FRANCIS CRICK INSTITUTE LIMITED;WATCHFROG;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;MEDICAL RESEARCH COUNCIL";"UK;ES;DK;FR";/LIF;1;0;0;1;0;0 98311;276976;CANCER-3DMATRIX-EGF;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-RG;FP7;Interactions of Breast Cancer Cells with Macrophages in Controlled 3D in vitro Microenvironments;2011-04-01;2015-10-01;;"The leading cause of death for cancer patients is metastasis. During metastasis, cancer cells interact with various molecules and cells. It has been shown that a group of macrophages facilitates metastasis. Our goal is to determine the mechanism of interaction between epidermal growth (EGF) produced by macrophages and epidermal growth factor receptor (EGFR) expressed by breast cancer cells. Soluble EGF or macrophage conditioned medium does not stimulate breast cancer cell invasion into collagen matrix and 6 kDa EGF is not detected in conditioned medium or cell lysates. Various growth factors are known to bind the extracellular matrix (ECM) and cells can move by haptotaxis (chemo-attractants are substrate-bound). What is more, breast cancer cells do not invade into collagen matrix when macrophages are not present. Based on the above, we will test the following hypotheses: 1) Breast cancer cells show chemotaxis to freely diffusing EGF in ECM. 2) Breast cancer cells show haptotaxis to ECM bound EGF. 3) Breast cancer cells are stimulated by EGF on the cell surface of macrophages. We will use UV lithography to prepare 3D microenvironments for cell culture and use confocal fluorescence microscopy to assay cell behavior and examine the ECM of macrophages. If EGF is soluble in 3D matrix, breast cancer cells will show increased motility with increased proximity to macrophages. If EGF binds to ECM, then ECM produced by macrophages will be able to stimulate breast cancer cell motility via stimulation of EGFR. If EGF stays on the surface of macrophages, breast cancer cells will not invade the matrix without direct contact with macrophages. This interdisciplinary project will establish an experimental system to study interactions between different cell types and will help develop novel diagnostic and therapeutic approaches and devices. The researcher will bring the state-of-the-art knowledge and know-how she has acquired in various international institutions, to Europe.";100000;100000;FP7-PEOPLE-2010-RG;/MC-IRG;IZMIR INSTITUTE OF TECHNOLOGY;TR;;;/SCI;1;0;0;1;0;0 108448;330623;SUPERCOLD;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IEF;FP7;Quantum scattering at ultracold temperatures: a few S-matrix columns is all we need;2013-09-01;2015-08-31;http://community.dur.ac.uk/m.l.gonzalez-martinez/supercold.html;"Technology in the future will rely on the quantum nature of matter. Quantum technologies would be impossible to develop without first understanding what quantum effects have to offer. It is thus crucial to study real quantum systems, for which ultracold atomic/molecular gases are ideal. This project is for the development and application of a novel approach to study molecular collisions at low temperatures. Its expected results will set a new standard in quantum scattering calculations and make feasible problems that are currently intractable. Standard approaches aim for an exhaustive description of the collision process and are nearly impossible to apply to questions of current experimental interest. We will implement a highly optimized code based on a key idea: in the ultracold regime, one is only interested in the properties of a few initial states, often just one. The code will improve on an algorithm proposed by LD Thomas to calculate all scattering information for a single initial state, which has not been used to study ultracold collisions. We will tackle systems for which experiments are currently under way, fostering comparison between theory and observations and interdisciplinary collaboration. Our approach is expected to answer many challenging questions on the success of cooling techniques to go below microKelvin temperatures, assist researchers in the design of novel experiments and lead to high-impact publications. The project is designed as a collaborative effort involving researchers from 5 institutions in as many EU states. The main work will be carried out in O Dulieu's group at Laboratoire Aimé Cotton, one of the world's leaders in the field. It will provide me with critical training in quantum scattering theory and ab initio techniques, and in transferable skills including project management, communication, presentation and creativity. It will significantly boost my career as an independent researcher and my chances to get an academic position.";194046,6;194046,6;FP7-PEOPLE-2012-IEF;/MC-IEF;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FR;;;/SCI;1;0;0;1;0;0 109766;618224;Endosignal;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-CIG;FP7;Endosignal;2013-09-01;2017-08-31;;Inflammatory bowel disease is a devastating disease affecting several million people in Europe. This proposal addresses the molecular mechanism of inflammatory bowel disease. The multi-PDZ domain protein FRMPD2 (FERM and PDZ domain containing protein 2) has been shown to be an integral part of the immune host defense of epithelial cells by recruiting NOD2 (Nucleotide-binding and oligomerization protein 2), a key player of the innate immune system, to the basolateral membrane in epithelial cells. In addition, FRMPD2 is involved in epithelial cell/cell adhesion regulating tight junction formation. Multi-PDZ domain proteins are scaffolding molecules assembling large protein complexes dedicated to signaling and membrane trafficking. Interaction of NOD2 with FRMPD2 places the NOD2 protein into a novel context being part of a larger protein complex. Using an interdisciplinary approach combining state of the art techniques from cell biology, protein chemistry, membrane physics and developmental genetics, this proposal aims at the identification and functional characterization of novel components of the FRMPD2 protein complex. In particular, this protein complex will be characterized with respect to mechanisms relevant to epithelial cell polarization and inflammatory bowel disease. Finally, the project aims to complement in vitro mechanistic and cell culture data with in vivo results by analyzing the role of the FRMPD2 complex in zebrafish development. Finally, using a Salmonella infection model, a zebrafish animal model for inflammatory bowel disease based on the FRMPD2 complex will be established. The results of this project will lead to a better molecular understanding of the disease opening potentially new avenues of treatments.;100000;100000;FP7-PEOPLE-2013-CIG;/MC-CIG;THE UNIVERSITY OF SHEFFIELD;UK;;;/LIF;1;0;0;1;0;0 95450;251685;MEDUSA;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IAPP;FP7;MEDUSA, a Meteorological Decision Support System for Aviation;2010-08-01;2014-07-31;http://www.medusa-fp7.eu/;"Weather contributes both directly and indirectly to incidents, accidents, and delays in air traffic and hence derogates safety and efficiency of airport operations. Today, the aviation stakeholders receive their meteorological information from different sources, at different update rates and with different levels of resolution and accuracy, often leading to misunderstandings and even wrong decisions. The goal of the project is to develop a MEteorological Decision sUpport System for Aviation (MEDUSA) to provide adequate information about adverse weather situations to all decision makers in the airport environment such as airports, air navigation safety providers, airlines, and weather services. MEDUSA is a highly interdisciplinary and intersectorial project dedicated to the scientific and technological development of an end-user oriented application in the field of aviation meteorology including a marketing and commercialization strategy. MEDUSA, combining scientific complexity with high requirements on technical robustness, will provide an integrated weather information solution to aviation. Adverse summer weather like thunderstorms and heavy precipitation), and adverse winter weather situations like heavy snow fall, icing and freezing conditions at the airport will be considered. Key for the technical development is the integration of the various meteorological products in a robust, reliable, and real-time operational system with an easy-to-understand visualization to assist end-users in daily decision making. The project is organized in four phases, (i) test of existing algorithms and forecasting modules and selection of best suited algorithms and modules; (ii) development of joint platform MEDUSA; (iii) implementation and test of MEDUSA at the airports Munich, Frankfurt, and Barcelona including end-users’ feedback to improve the prototype; and (iv) dissemination of the results to the scientific and end-user communities and commercialization.";546600;546600;FP7-PEOPLE-2009-IAPP;/MC-IAPP;Hydrometeorological Innovative Solutions;ES;DEUTSCHES ZENTRUM FUER LUFT - UND RAUMFAHRT EV;DE;"/SCI;/EDU;/ITT";1;0;0;1;0;0 108787;328259;HegelandRicoeur;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IEF;FP7;Misrecognition, mutual Recognition and Forgiveness in Hegel and Ricoeur;2013-09-01;2015-08-31;;"The present project pursues a twofold objective: firstly, it aims to frame Ricoeur’s position in the contemporary and interdisciplinary debate on mutual recognition (Anerkennung), highlighting original traits of Ricoeurian reception in the Hegelian category; secondly, it is designed to make a theoretical comparison between the way in which Ricoeur and Hegel interpret the nexus among misrecognition, Anerkennung and Forgiveness, in the conviction that such a comparison – pointing out convergences and divergences – may help both to cast new light on the positions of both thinkers and to advance the “theory of recognition” further. The choice of the three terms in the project’s title - Misrecognition, Anerkennung and Forgiveness – expresses the interpretative hypothesis from which to begin: the hypothesis that Ricoeur uses in an original and simultaneous way both the generative nexus that Hegel poses between misrecognition and recognition – interpreting the latter as the fruit of a struggle – and the theme of forgiveness as the only form of genuine recognition, as developed in the Phenomenology of Spirit. The objectives of the project will be pursued through a deep and exhaustive exploration of Ricoeur’s lifelong and ambiguous confrontation with Hegel’s thought, with particular attention to the points of intersections of such a confrontation with the intense dialogue that Ricoeur has constantly conducted with the principal theoreticians of the twentieth-century human sciences. The accomplishment of the project proposed, thanks to a Marie-Curie-fellowship, would therefore not only contribute to fill in a relevant gap in the secondary literature on Ricoeur, but could also furnish valuable theoretical resources with which to enrich the European philosophical paradigm of recognition and to enlarge its field of application to encompass other fields of the human sciences, such as historiography and law.";269743,8;269743,8;FP7-PEOPLE-2012-IEF;/MC-IEF;INSTITUT PROTESTANT DE THEOLOGIE ASSOCIATION;FR;;;/SCI;1;0;0;1;0;0 108572;322669;PROTISTWORLD;ONG;FP7-IDEAS-ERC;ERC-AG-LS8;FP7;Protist evolution in suboxic worlds;2013-09-01;2018-08-31;;How and when eukaryotes evolved remain major open questions. Also the phylogenetic relationships and the emergence order of major eukaryotic lineages remain unresolved, despite progress in phylogenomic analyses based on genome and transcriptome data across the eukaryotic tree. However, this information is biased towards multicellular taxa. Yet, environmental molecular analyses have uncovered a vast diversity of protists (broadly, microbial eukaryotes), many of which have uncertain phylogenetic position. Phylogenomics also suggests that endosymbiosis (e.g. mitochondrial acquisition) played a key role in eukaryotic evolution, shaping their genomes and leading to innovations. The first eukaryotes likely evolved in anoxic or transition-to-oxic (suboxic) environments, which may hold clues as to the occurring selective constraints, prior to colonizing new niches thanks to oxygen-respiring mitochondria. Despite so, little is known about the diversity and mode of evolution of eukaryotes in suboxic worlds, including microbial mats and stromatolites, where many inter-species interactions are likely to exist. I propose an integrative interdisciplinary approach to gain significant knowledge about early eukaryotic evolution according to the following hypotheses: i) High diversity suboxic environments, such as microbial mats, hide novel divergent protist lineages. ii) The study of natural fossilization processes of microbial eukaryotes in calcifying microbial mats such as stromatolites will lead to the definition of biosignatures in the past fossil record and to establish reference dates for the origin of eukaryotes and/or particular eukaryotic taxa. iii) Phylogenomic analysis of divergent protist lineages from suboxic environments will help resolving the eukaryotic tree of life and dating major splits in eukaryotic lineages. iv) Protist symbiosis with prokaryotes is widespread in suboxic worlds and that (endo)symbiotic-gene transfer has an important impact in protist evolution.;2039812,27;2039812,27;ERC-2012-ADG_20120314;/ERC-AG;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FR;;;"/BIO;/LIF";1;0;0;1;0;0 104659;317232;FQT;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-ITN;FP7;Frontiers in Quantum Technology;2013-09-01;2017-08-31;;'Mission Statement: To deliver an internationally competitive student cohort who will be equipped to be the research and industry leaders of the future through interdisciplinary training at the frontiers of Quantum Technology. The ability to engineer materials at the atomic level has led to the enormously active field of nanotechnology: the analysis, design and fabrication of devices that operate at the leading-edge of optical and electronic technology. This technology has inevitably revealed the true quantum nature of the microscopic world, where particles and waves co-exist and interact in novel exciting ways. The study of quantum information and quantum technology has now been around for some time, and this is the ideal opportunity for the fundamental science to work with industrial researchers to make advancements which the market wants, rather than those which serve only the scientists’ curiosities. Along this line, we have identified two strands of research themes, namely, the generation of extreme light sources and the study of light-matter interactions, with a view to the development of quantum technology. Imperial College has a large team of researchers (17 members of academic staff and 50 postdoctoral fellows: research grants over ?30m) working at the leading edge of quantum sciences encompassing surface plasmonics, cold atoms, attosecond lasers and quantum theory. Coupled with newly refurbished postgraduate lecture facilities, a brand new state-of-the-art workshop, and new offices for the quantum theory group this makes Imperial ideal for student training. The associated partners include top academic institutes, government labs and private companies which will be actively involved in student recruitment, research and training. Imperial has been known for attracting world’s best students and with the current IDP we will be able to train those students to become leading scientists with the creative ideas to answer the beneficiaries’ needs.';3816691,12;3816691,12;FP7-PEOPLE-2012-ITN;/MC-ITN;IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE;UK;;;/LIF;1;0;0;1;0;0 99015;267229;ICFONEST;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-COFUND;FP7;ICFONest International Postdoctoral Program;2011-01-01;2015-06-30;;"The ICFONest Post-doctoral program aims to provide high-level training and support for 14 outstanding international researchers in the early stages of their careers, working in the field of Photonics. ICFO will provide cutting edge facilities as well as a stimulating, international and interdisciplinary environment to help Fellows become successful independent researchers. ICFO currently hosts 20 research groups working in 50 different laboratories. Available to them are a nanofabrication cleanroom and a range of other support facilities. All research groups and facilities are located in a dedicated 10.000 m2 -building situated in the Mediterranean Technology Park in the metropolitan area of Barcelona. Currently, ICFO counts about 200 researchers, a number that is continuously growing. By 2014, when ICFO completes its ongoing expansion phase, the Institute will count more than 300 researchers working in 25 different research groups. Research at ICFO encompasses four broad thematic areas: nonlinear photonics, quantum photonics, nanophotonics, and biophotonics. Researchers work in a great variety of fields, including quantum information technologies, nanophotonic devices, remote sensors, optoelectronics, integrated optics, ultrafast optics, biophotonics, and biomedical optics. Projects are run as part of both medium- and long-term programs. The ICFONest COFUND program will run for four years and during this time it will support rising top-class researchers with excellent facilities, competitive salaries, research expenses and support from Group Leaders. During the period, the program will award 14 outstanding post-doctorate researchers with INCOMING Fellowships. ICFO will also offer specialised business courses and complementary training programs as well as a wide range of events, seminars and colloquia involving world-renowned scientists.";2107252;842900,8;FP7-PEOPLE-2010-COFUND;/MC-COFUND;FUNDACIO INSTITUT DE CIENCIES FOTONIQUES;ES;;;"/SOC;/COO;/NET";1;0;0;1;0;0 103822;299137;AYNP;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IEF;FP7;Antwerp Yiddish Noun Plurals;2012-09-01;2013-08-31;;"'The proposed project will explore structure and acquisition in contemporary Yiddish used by the Jewish Ultra-Orthodox (UO) community in Antwerp, Belgium. This community lives in a unique multilingual situation that includes three main languages; Yiddish and Dutch - two living languages competing as native tongues, and Loshn Koydesh(Classical Hebrew) - restricted only for praying and not used for daily communication. Our window onto native Antwerp Yiddish is the system of noun plurals, whereby a singular noun (e.g. kind 'child') takes on a plural suffix (kinder 'children'). The aim of the project is two-fold: First, to describe the system of noun plurals as it is currently used by adults, taking into account the intensive contact with Dutch, and second, to understand how this system is acquired by children from the same community. In order to achieve these aims, the project will include two phases: the first is the Baseline Study, in which a confrontational noun plural naming task will be administered to 100 Antwerp Yiddish speaking adults. Data analyses will describe and explain the properties of the plural system in Antwerp Yiddish. This baseline will serve as the basis for the second phase of our project – the Developmental Study, in which 100 UO children in five age groups (3, 5, 7, 9, 11) will be administered two tasks: (1) a structured noun plural naming test and (2) a semi-structured naming test based on a set of pictures. Data will be analyzed according to methods of quantification of morphological diversity as well as quantitative normalization procedures in corpus analysis. Thus, this project will enable an international collaboration between the applicant's research experience in the Israeli context, and the linguistic expertise available in Antwerp University. This interdisciplinary cooperation will facilitate transfer of knowledge and training skills for the benefit of the applicant's career development and the enrichment of the European research area.'";88500;88500;FP7-PEOPLE-2011-IEF;/MC-IEF;UNIVERSITEIT ANTWERPEN;BE;;;/SCI;1;0;0;1;0;0 107473;327168;TUSCOPAL;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IOF;FP7;Tunable Strong Coupling Phenomena at Atomistic Level;2013-09-09;2017-03-08;;"Understanding the dynamics of fundamental strong coupling processes such as crystallization (liquid-solid phase transition) and glass transition (metastable, supercooled liquid-glassy state phase transition) at the individual particle level is of great importance in interdisciplinary research combining physics, chemistry and biology. Colloids are the best model systems to investigate these processes, but most of the relevant works have been performed with hard sphere model of the interacting particles. The goal of this project is to explore the universal phase diagram of such processes for different interaction potentials: from ultra-soft to hard sphere or from repulsive to attractive, etc. The experiments will be performed at Harvard University, USA (Outgoing host). The soft PNIPAM microgel particles will be synthesized using microfluidic technique. The interaction potential of these particles can be tuned by changing the surrounding temperature. Then dedicated experiments will be performed on crystallization and glass transition using confocal microscope and particle tracking techniques. On his return to Heinrich Heine University, Germany (Incoming host in Europe), the fellow will be trained to develop complementary theoretical and numerical models (Brownian dynamics for colloids and Molecular dynamics for complex plasmas). Additionally, he will try to explore complementarity of complex plasmas and colloids. The fellow is a member of “European Soft Matter Infrastructure (ESMI)”. He is an expert on complex plasma research, which shares complementary features with colloids. The proposed project will help him to gain expertise on colloids. In future he will emerge as one of very few scientists in Europe who will have expertise on both subjects. The fellow will also be trained with teaching activities, complementary skills, knowledge and technology transfer know-how to Europe, which will help Europe to remain at the frontier of this fundamental research area.";263448,6;263448,6;FP7-PEOPLE-2012-IOF;/MC-IOF;HEINRICH-HEINE-UNIVERSITAET DUESSELDORF;DE;;;/LIF;1;0;0;1;0;0 96424;255614;RACIALISM;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IEF;FP7;"""""""Racial thinking and relevant sciences in East-Central Europe in the decades around 1900""""""";2011-09-01;2014-02-28;;At the core of my proposed research lies the desire to understand turn-of-the-century European fascination with the idea of race and the employment of modern sciences in the construction of racial theories in national and imperial contexts of East-Central Europe. The project will explore the history of racial thinking and related biological, human and social sciences in the mostly uncharted region of East Central Europe, with special focus on the Hungarian Kingdom in the decades around 1900. Rooted in the ethnically and confessionally most mixed region of contemporary Europe, Hungarian sciences faced unique intellectual challenges in constructing racial theories and creating ethnic, national and imperial identities, thus contributing to the process of Hungarian nation-building while legitimating liberalism in general. To understand how race, ethnicity, the nation and the multi-ethnic kingdom were co-produced in the region, systematic research will explore a variety of scientific disciplines, including ethnography, sociology, physical anthropology, criminal and social statistics, biology, public health, eugenics, and crowd psychology. Based on the Applicant’s preliminary studies and research hypotheses, the disciplinary trajectories of Hungarian ‘sciences of race’ seem to diverge considerably from the models offered by the historiography in the British, French and German contexts. Rather exceptionally, in the Hungarian intellectual field, a marked and overall shift towards a biological, hierarchical, and racialist thinking did not seem to have taken place before the end of WWI. Due to the originality of the research and its interdisciplinary nature, the planned outcome, a monograph, will contribute not only to the historiography of European “racial sciences” and science studies, but also to nationalism and imperialism studies, the cultural and social studies of fin-de-si?cle modernity in Central Europe, and the wider scholarship on the Austro-Hungarian Empire.;148202;148202;FP7-PEOPLE-2009-IEF;/MC-IEF;KOZEP-EUROPAI EGYETEM;HU;;;"/SCI;/EDU;/ITT";1;0;0;1;0;0 99383;275180;MiMe;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-IIF;FP7;The Role of Microbial Metabolites in Pb-Calcite Surface Interactions;2011-09-01;2013-08-31;;"The behavior of metals, many of which are toxic even in trace quantities, is an important topic as population growth puts pressure on the world’s drinking water resources. Relatively little is yet known about the interdependencies between the biotic and abiotic aspects of metal sorption. The overall aim of my project is to define the processes by which microbial metabolites mediate Pb sorption on calcite. I will use a combination of surface sensitive techniques, including X-ray Photoelectron Spectroscopy (XPS), Atomic Force Microscopy (AFM), and Quartz Crystal Microbalance with Dissipation Monitoring (QCM-D) to extend current understanding of the biogeochemical controls on Pb behavior to the molecular scale. My study lies at the intersection of geoscience, surface physics and biointerface science and uses an interdisciplinary approach to answer questions at the crossover of environmental bio- and geochemistry, that are critical for society. The results will provide insights for the water industry, so treatment can be improved by providing criteria for selecting bacteria that can synthesize particular metabolites to immobilize specific toxic metals. Internal corrosion of Pb pipes in water distribution systems is currently an immediate, world-wide public health concern. A recent study estimated that 25% of houses in the EU have at least one Pb pipe, putting 120 million Europeans at risk. My background in drinking water treatment, the new expertise I will gain and the results from the MiMe project will address this concern. I bring my experience and motivation to the members of the Nano-Science Center, to exchange for the opportunity to learn new skills on a set of unique instruments that can “see” at the molecular-level. This new knowledge will form the base for my future research. Indeed, my host, Prof. Stipp’s expertise in the nano-scale processes on mineral surfaces is at the top of the field; I will benefit tremendously from my time at the University of Copenhagen";230627,2;230627,2;FP7-PEOPLE-2010-IIF;/MC-IIF;KOBENHAVNS UNIVERSITET;DK;;;"/SOC;/COO";1;0;0;1;0;0 98821;272463;LEIBENLIG;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-IEF;FP7;"""Leibniz’s Enlightenment. Debates on Faith and Reason in Early modern Europe, 1668-1710""";2011-09-01;2013-08-31;;'The project is a historical reconstruction of the philosophical debates concerning faith and reason in the Early Modern Republic of Letters as seen through the eyes of the German polymath G.W. Leibniz (1646-1716). It will be conducted at the Centre d’Etudes en Rhétorique, Philosophie et Histoire des Idees (CERPHI UMR 5037), a research unit based at the École Normale Supérieure in Lyon. It will be supervised by the director of CERPHI, Professor Pierre-François Moreau. The project contains three parts. First, it reconstructs the conceptual framework, which governs Leibniz’s analysis, evaluation and strategic approach to other thinkers, positions and doctrines in the early modern Republic of Letters, with special emphasis on the controversies concerning faith and reason. This provides a historically immanent methodological framework for the study of those debates. It also provides an original account of Leibniz’s position as a philosopher in the Early Modern Republic of Letters, a powerful proponent of what is today referred to as the “moderate Enlightenment.” In Part II, I study in detail Leibniz’s engagement with a series of other, contemporary theoretical positions on the relations between faith and reason. These positions include Padouan Averroism, Mechanism, Naturalism and Materialism, Catholic Fideism, Erudite Libertinism, Theological and Philosophical Enthusiasm, Rational theology, and Calvinist Scepticism. The seven case studies currently planned form the bulk of the project. Finally, in Part III, the project includes a set of appendices containing translations into English of a series of generally unknown French and Latin texts by Leibniz. The project is a strongly interdisciplinary and draws on research from both philosophy, history, theology, comparative literature, and the history of science.';254775;254775;FP7-PEOPLE-2010-IEF;/MC-IEF;ECOLE NORMALE SUPERIEURE DE LYON;FR;;;"/EMP;/EDU;/NET";1;0;0;1;0;0 107323;318997;NEUREN;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IRSES;FP7;NEUREN - Neuroscience Research Exchange Network (NEUREN);2013-09-01;2017-08-31;;"'The NEUREN project is based on an interdisciplinary consortium of 14 laboratories from 4 EU countries (France, Italy, Spain, Poland), 3 industrialized countries (Australia, Canada, USA) and 3 Mediterranean countries (Egypt, Morocco, Lebanon). It covers a large scope of Neuroscience research topics from molecules to integrated physiology, associate basic, translational, and clinical research, from bench to bedside. EU institutions all share similar basic competences but they show significant complementarities to cover all aspects of Neuroscience. Third countries partners bring their own technical and conceptual expertise to build a consortium of excellence, taking advantage of previous collaborations to exploit existing complementary expertise and synergy between the partners. Given the complexity of neurobiological processes, and the broad range of methodological approaches, it is absolutely necessary to develop multi-sites integrated research projects. Therefore, 6 multi-sites projects have been elaborated, using staff exchange as a tool to develop research collaborations. • Pain sensitization in the spinal cord (Bordeaux, Alexandria, Melbourne, Laval, Turin) • Experimental models for neurological disorders (Turin, Marrakech, Alexandria, NY) • Systems neurobiology of neurological disorders (Valence, Tetuan, Krakow, Melbourne) • Cognitive impairment and neuronal dynamics (Marseille, Alexandria, Marrakech) • Dysfunction of the prefrontal cortex and trait anxiety (Nice, Marrakech) • Medical imaging of neurological disorders (Bordeaux, Laval, Beirut) Such consortium will highly support the current efforts to reach outstanding international research standards. It will contribute to develop poles of technical and scientific excellence that will become the reference for the South Mediterranean area. Northern institutions will fully benefit from this integration to further diversify their technical expertise and to aggregate powerful teams of well-trained researchers.'";304200;304200;FP7-PEOPLE-2012-IRSES;/MC-IRSES;UNIVERSITE DE BORDEAUX;FR;"UNIVERSITAT DE VALENCIA;UNIVERSITA DEGLI STUDI DI TORINO;UNIVERSITE VICTOR SEGALEN BORDEAUX II;UNIWERSYTET JAGIELLONSKI;UNIVERSITE D'AIX MARSEILLE";"ES;IT;FR;PL";/SCI;1;0;0;1;0;0 91961;229677;RSE IRAS;ONG;FP7-PEOPLE;PEOPLE-2007-2-3.COFUND;FP7;Royal Society of Edinburgh International Research Awards Scheme;2009-03-30;2015-03-29;;The Royal Society of Edinburgh (RSE) runs Fellowship ?schemes for postdoctoral researchers, the largest and most prestigious of ?which is the Scottish Government funded scheme for six 5-year ?Fellowships per year. RSE wishes to enhance this scheme.? The support costs provided over the Fellowship period are limited and ?have to cover equipment, consumables and travel. This constrains ?mobility of Fellows. RSE wishes to make travel funds available to enable ?Fellows to spend up to twelve months overseas to encourage them to foster ?collaborative links with researchers outside the UK. RSE will also ?support the cost of more skills training for Fellows.? The COFUND contribution will be paid in the first two years of the ?Fellowship so that trans-national mobility occurs early in the Fellowship ?and networks are developed over the 5-year period. The Fellow will be ?able to spend quality time with the collaborative partner, and will have ?time to experience the culture of the host country. These opportunities are ?valuable in the Fellow’s career and personal development, encouraging ?the formation of long-term research networks. The COFUND contribution will also enhance an existing RSE ?international exchange scheme that supports short-term visits before, ?during and after Research Fellowships. It helps to develop initial contacts, ?build on previous research collaborations and link with research groups ?overseas. Collaborative links are supported over the longer term to assist ?in the development of trans-national research networks. This aspect of the ?Marie Curie scheme will thus enable overseas collaborators to work in ?Scotland with the Fellow and assist in the Fellow’s reintegration by ?reinforcing networks. In the enhanced scheme, experienced researchers will have broader ?opportunities through their choice of topic, destination and research group ?to develop multi or interdisciplinary skills enabling them to build long-?term international partnerships.;2165450,71;866180,28;FP7-PEOPLE-2007-2-3-COFUND;/MC-COFUND;THE ROYAL SOCIETY OF EDINBURGH;UK;;;"/REG;/SCI";1;0;0;1;0;0 109674;618116;ATOMIC SCALE GFM;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-CIG;FP7;Atomic Scale Group-IV Materials for Beyond-CMOS Applications;2013-09-01;2017-08-31;;"I will systematically exploit the quantum properties in Group-IV Materials (GFMs) at the atomic scale, by using top-down patterning processes developed for Si technologies. Among GFMs, I will examine graphene, Si, and Ge nano-structures, since these materials are technologically important. More specifically, I will use our He-Ion-Microscope (HIM) milling techniques to fabricate nano-structures beyond the resolution limit of conventional lithography. This research will: 1. Characterize Freestanding Mono-layer or thin-layer of GFMs I will fabricate the freestanding device structure by HIM. The high-resolution of HIM will enable me to fabricate the graphene nano-ribbon as narrow as 5-nm. I will also examine the atomic structures of the device by Transmission-Electron-Microscope (TEM), and compare it with electrical measurements. The similar devices can be made for ultra-thin Si films. 2. In-situ formation and characterization of Si Quantum Dot (QD) I will characterize the Si Single-Electron-Transistor with a QD by in-situ monitoring in HIM. 3. Characterization of SiGe Fins I will characterize SiGe Fin for high performance electro-absorption optical modulator applications. Impacts of the projects to EU are expected as following ways: 1. I will contribute in the interdisciplinary research areas with my strong research background in theoretical physics, nano-electronics, and Si Photonics. 2. The long-term research activities to QIP will be continued for secure communication and massive commutation, beyond the limit of the classical computations. 3. I will transfer my research experience from Japan. Especially, the industrial experience in Hitachi is helpful for running the clean room managements. 4. I will explore the innovative opportunities for sustainable electronics, in which EU communities play the important contributions towards the matured smart society. 5. I would like to establish the various collaboration within EU and internationally.";100000;100000;FP7-PEOPLE-2013-CIG;/MC-CIG;UNIVERSITY OF SOUTHAMPTON;UK;;;/LIF;1;0;0;1;0;0 109765;618183;HUMCONST2013;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-CIG;FP7;International Protection of Human Rights as a Constitutional Issue: Promises, Problems and Prospects;2013-09-01;2016-06-30;;"International law is distinguished from other branches of law by the fact that States as its principal subjects are not only the addressees of law, but also creators of legal rules and guarantors of their enforcement. The idea of international constitutionalism attempts to place some constraints on the power exercised by States. Human rights form today a core of any Western constitutional order. However, the role of international human rights within international constitutionalism is articulated only rudimentarily. The project aims at filling this gap by analyzing current discourses on international constitutionalism and human rights in literature and jurisprudence of the International Court of Justice through an interdisciplinary and critical lens. Theoretically sound, practice- and policy- oriented proposals as to the more adequate articulation of the relationship between human rights and international constitutionalism will be formulated. In order to fulfill the aims of the project methodological tool developed in history, philosophy and sociology will be used. In order to seek new avenues for a more adequate fulfillment of human rights’ promise of protection the project will seek inspiration in non-western (Islamic law) and extra-legal (ancient Greece) normative orders. Through funding of research the grant will support successful integration of a promising academic into European research community and her establishment as a leading specialist in the field of human rights. It will also promote establishment of a research team and widening of the international network of the researcher. The Grant will thus contribute to the growing excellence of European research community and establishment of lasting collaboration with extra-European academic institutions.";70833,33;70833,33;FP7-PEOPLE-2013-CIG;/MC-CIG;NATIONAL UNIVERSITY OF IRELAND GALWAY;IE;;;/LIF;1;0;0;1;0;0 107707;323743;GRECO;ONG;FP7-IDEAS-ERC;ERC-AG-SH2;FP7;Grassroots economics: Meaning, project and practice in the pursuit of livelihood;2013-09-01;2018-08-31;;"In Southern Europe promises of wellbeing and social mobility have become increasingly elusive since 2008. Economists and policy makers have provided analyses and advised on political action to end the economic crisis, but this has often resulted in greater precarity producing social protest as well as nationalistic and xenophobic reactions. Expert’s accounts are based on mainstream economic models designed to provide monetary stability and growth through enhanced competition in open markets. These models are ‘technical’ and top-down models that largely ignore political, social and cultural dynamics on the ground. Yet social agents are embedded in multiple regimes of value and institutional frames that guide their economic behavior. Four Southern European countries –Portugal, Italy, Greece and Spain— have been strategically selected as research sites due to their relevance in the current European crisis. The project investigates grassroots economics by addressing the social, cultural and political environments in which common people make everyday economic decisions. Through an interdisciplinary approach that uses ethnographic fieldwork and comparative analysis, it highlights the interaction between individuals, households and institutions from a threefold perspective 1) as creating meanings in which the value(s) of action are assessed, 2) as defining the material and ideological conditions of possibility for designing projects, and 3) as providing resources and creating various distribution patterns. It explores the relationship between authoritative models of the economy and the real economic projects and practices of those whose main objective is the pursuit of livelihood. The comparison of grassroots economics with mainstream expert economics will support a theoretically ground-breaking explanatory framework that will shed light on ongoing problems of livelihood insecurity and policy design that are currently left unaddressed by economic policies.";2408302;2408302;ERC-2012-ADG_20120411;/ERC-AG;UNIVERSITAT DE BARCELONA;ES;;;/SOC;1;0;0;1;0;0 109748;320377;NetSat;ONG;FP7-IDEAS-ERC;ERC-AG-PE8;FP7;Networked Pico-Satellite Distributed System Control;2014-08-01;2019-07-31;;"A paradigm shift is emerging in spacecraft engineering from single, large, and multifunctional satellites towards cooperating groups of small satellites. This will enable innovative applications in areas like Earth observation or telecommunication. Related interdisciplinary research in the field of formation control and networked satellites are key challenges of this proposal. Modern miniaturization techniques allow realization of satellites of continuously smaller masses, thus enabling cost-efficient implementation of distributed multi-satellite systems. In preparation my team has already realized two satellites at only 1 kg mass in the University Würzburg’s Ex¬perimental satellite (UWE) program, emphasizing crucial components for formation flying, like communication (UWE-1, launched 2005), attitude determination (UWE-2, launched 2009), and attitude control (UWE-3, launched 2013). My vision for the proposed project is to demonstrate formation control of four pico-satellites in-orbit for the first time worldwide. To realize this objective, innovative multi-satellite networked orbit control based on relative position and attitude of each satellite is to be implemented in order to enable Earth observations based on multipoint measurements. Related sensor systems used in my laboratory in research for advanced characterization of teams of mobile robots will be transferred to the space environment. Breakthroughs are expected by combining optimal control strategies for coordination of relative motion with a robust flow of information in the network of satellites and ground stations, implemented via innovative use of ad-hoc networks in space. Based on my team’s expertise in implementing very small satellites, first time a system composed of four satellites will be launched to demonstrate autonomous distributed formation control in orbit. This research evaluation in space is expected to open up significant application potential for future distributed satellite system services in Earth observation.";2500000;2500000;ERC-2012-ADG_20120216;/ERC-AG;Zentrum fuer Telematik e.V.;DE;JULIUS-MAXIMILIANS-UNIVERSITAT WURZBURG;DE;"/PSE;/MAT;/IND;/CON";1;0;0;1;0;0 99319;275357;ARDIS;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-IEF;FP7;Academic Researchers Driving Innovation Systems;2011-09-01;2013-08-31;;"'Academic researchers form a crucial part of innovation systems but research so far leaves room for the following three questions: how does social capital of academic researchers co-evolve with the use, creation and dissemination of knowledge and innovation? Two, how do academic researchers’ innovation systems function at the regional, national and global level? Three, are the research activities and goals, the knowledge accumulation and the networks of academic scholars characterized by their technical disciplines? In particular, the applicant aims at developing a taxonomy of academic researchers that goes beyond basic and applied research. The approach used for the project has three major distinguishing characteristics: One, it is a comparative approach as the applicant will analyse the situation at five leading European universities of science and technology. These universities form the IDEA league and include a British, Dutch, French, German and Swiss partner. Two, the approach is interdisciplinary as the applicant will join the perspectives of two disciplines, i.e. Economic Geography and Economics of Innovation. Three, the applicant uses a theory-driven empirical approach by combining quantitative, i.e. social network analysis and bibliometric analysis, and qualitative research methods in an innovative way. The approach taken mirrors the aim of the research training project. The applicant has a strong theoretical background in Economics of Innovation and empirical experience in quantitative research methods. Her stay at the RWTH Aachen University would enhance her knowledge of Economic Geography and of qualitative research methods. The insights regarding patterns, dynamics and effects of knowledge-intensive networking of academic researchers will hint at chances and bottlenecks in innovation systems. They will help academic researchers, university management and policy makers to improve the research efficiency and output of the European Research Area.'";217245;217245;FP7-PEOPLE-2010-IEF;/MC-IEF;RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN;DE;;;"/EMP;/EDU;/NET";1;0;0;1;0;0 109773;618548;FuncCahnHilliardPNP;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-CIG;FP7;Variational models of network formation and ion transport: applications to polyelectrolyte membranes;2013-09-01;2017-08-31;;"The functionalized Cahn-Hilliard energy is a phase-field characterization of an interfacial energy used to describe dynamics of amphiphilic network formation. We have successfully applied the functionalized Cahn-Hilliard energy to model the morphology of water nano-pore networks in ionomer membranes. The resulting morphology model was validated with experimental scattering data of Nafion, an ionomer membrane which is a critical component in fuel cells. It is natural to use, as a basis, the successful morphology model to study the effect of morphology on membrane performance, e.g., conductivity. The functionalized Cahn-Hilliard energy offers, however, only a phenomenological treatment of the electrostatic forces between the polymer and the water. Such a treatment effectively blocks important extensions of the model. The main goal of this proposal is the development, analysis, and simulation of continuum models which characterize amphiphilic network formation coupled to ion transport. Attaining this goal requires redeveloping key components of the functionalized Cahn-Hilliard model while operating on a wide range of scales, e.g., from the non-uniform water structure in a pore at the nanoscale to membrane conductivity at the macroscale. A key application of this proposal is to study conductivity and selectivity of ionomer membranes and their dependence upon morphology and ionic concentrations. The project is of clear interdisciplinary nature, merging problems, ideas and tools from Mathematics, material science, solution chemistry and soft matter physics. The design and performance of novel clean energy devices such as fuel cells, flow batteries, or organic solar cells critically depends on the optimized coupling between material nanostructure, electrostatics, charge transport and nanoflows. Any progress in the directions proposed above will open the way to robust phase-field models which can incorporate and couple these four effects.";100000;100000;FP7-PEOPLE-2013-CIG;/MC-CIG;TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY;IL;;;/LIF;1;0;0;1;0;0 109231;324214;EAST-WEST;ONG;FP7-IDEAS-ERC;ERC-AG-SH2;FP7;Vernacular religion on the boundary of Eastern and Western Christianity: continuity, changes and interactions;2013-09-01;2018-08-31;;"This interdisciplinary research project, relying on mutually complementary historical, anthropological and folklore investigations, will examine continuities and transformations in vernacular religion in the border-zone between Eastern and Western Christianity. The project will have three foci: 1) the role of the religious worldview and norms in past and present communities; 2) change and religious modernisation including the intertwining of the breaking up of the traditional worldview and the appearance of consumer-type attitudes of New Age religiosity; 3) the role of religion in identity formation and the emergence of religious pluralism and co-operation as well as of religious antagonism and conflict between different denominations and nationalities in the region. Members of the project will study these questions in Hungarian, Romanian, Serbian, Ukrainian and Croatian communities of mixed religion. Thematically the research will be organised around exploring symbolic exchange relationships (demonology and witchcraft) sacred communication (shrines, visions, miracles, saints) and healing using both historical sources and contemporary anthropological field work. The project builds on two previous long-term historical/folkloristic research projects led by PI Éva Pócs and will expand and complement their findings through contemporary anthropological field research and continued archival work. Integrating the results of the current and earlier projects through an innovative electronic document collection, embedded in a geographical information system, will enhance the impact of both sets of materials. The research will bring us closer to understanding a) inter-religious relationships between Catholic, Protestant and Orthodox believers, b) problems of national identity underlying religious antagonisms, and c) how religious and cultural border zones separate and unite, generate conflict and create mutual understanding, potentially promoting peaceful co-existence.";2079484,8;2079484,8;ERC-2012-ADG_20120411;/ERC-AG;MAGYAR TUDOMANYOS AKADEMIA BOLCSESZETTUDOMANYI KUTATOKOZPONT;HU;PECSI TUDOMANYEGYETEM - UNIVERSITY OF PECS;HU;/SOC;1;0;0;1;0;0 108742;315988;EPIGENESIS;ONG;FP7-REGPOT;REGPOT-2012-2013-1;FP7;One Health approach to integrate Guadeloupe research on vector-borne and emerging diseases in the ERA: from characterization of emergence mechanisms to innovative approaches for prediction and control;2013-09-01;2016-08-31;http://epigenesis.cirad.fr/;"Infectious emerging diseases involving arthropod vectors or vertebrate hosts threaten human health and stock breeding worldwide and respond fast and strongly to global change (intense travel and trade, natural hazards, societal and climate change…), particularly in the Caribbean with increased risk of diseases outbreak. Anticipation of health crises through relevant research programmes and innovative disease-control strategies is thus necessary to preserve animal health, food security and human health in interconnected Caribbean territories and Europe. The objective is to expand Guadeloupe research potential on emerging and vector-borne diseases along the ‘One-Health’ concept to improve the capacity of prediction and decision makers’ anticipation. The project will rely on an integrated approach, from genomics to surveillance and prevention strategies based on interdisciplinary analysis, aimed at facilitating the adoption of new knowledge by all stakeholders. Specific objectives are: (i) reinforce Guadeloupe S&T potential on emerging and vector-borne diseases through the acquisition of a biosecurity laboratory Level 3 and recruitment of experienced scientists; (ii) develop strategic partnerships with outstanding European research entities (exchange of scientists, training); (iii) disseminate scientific information and knowledge to the scientific community, decision-makers and the public, (publications, meetings, web site); (iv) increase Guadeloupe innovation potential (diagnostic, vaccines, surveillance tools). Sustainability will be ensured by paving the way for a Caribbean centre of excellence on emerging and vector-borne diseases, in collaboration with CaribVET and European partners. It will result in a better integration in the ERA for the research community and upgraded RTD capacity. With support of the regional authorities and Structural Funds, it will contribute to regional development: alert system for disease outbreak, path to smart specialisation.";5482207;3526011;FP7-REGPOT-2012-2013-1;/CSA-SA;CENTRE DE COOPERATION INTERNATIONALE EN RECHERCHE AGRONOMIQUE POUR LEDEVELOPPEMENT - C.I.R.A.D. EPIC;FR;;;/SCI;1;0;0;1;0;0 101188;289642;OPTIMA;ONG;FP7-KBBE;KBBE.2011.3.1-02;FP7;Optimization of Perennial Grasses for Biomass Production;2011-10-01;2015-09-30;http://www.optimafp7.eu/;"OPTIMA will integrate an ambitious biology system approach for perennial grasses such as switchgrass, miscanthus and giant reed in the Mediterranean environment. Moreover the perennial species cardoon, which has been proven to be particularly adapted to the Mediterranean climate, will be used as a control species. The main objective of the OPTIMA project is to identify high-yielding perennial grasses for the Mediterranean area, within optimized production chain that will provide stable source for both biomass and new plant derived bio-products. OPTIMA will explore the potentialities of perennial grasses on underutilized or abandoned marginal lands. An interdisciplinary approach involving physiology, biotechnology, and agronomy, socio-economical and environmental analysis at different scale levels will be undertaken with the aim at tackling specific bottlenecks of perennial grasses in the Mediterranean area and to create alternative end-use chains. OPTIMA approach has been to link the research proposed here by including industrial end-users in the project. This should allow the output of this research to develop in a commercial context as rapidly as possible the new findings. The major goals of this multidisciplinary network are to evaluate the existing genotypes; to characterize and deliver novel species; to deliver sustainable crop management practices (sowing/planting strategies to reduce the use of pesticide and increase biomass on the first year establishment, cultivation under salinity conditions and/or water deficit, reducing losses during harvest); to evaluate the industrial production of bioenergy and added value bio-products; to assess the environmental impact through an integrated assessment of sustainability criteria, to disseminate the achieved findings at different level (local, regional, national, international).";3913249,84;2998319;FP7-KBBE-2011-5;/CP-TP;UNIVERSITA DEGLI STUDI DI CATANIA;IT;"SPAPPERI S.R.L.;UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN;IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE;INSTITUTO DE AGROBIOTECNOLOGIA ROSARIO S.A.;PRIMUS TALALMANYHASZNOSITO, TERMELO, KERESKEDELMI ES SZOLGALTATO KORLATOLT FELELOSSEGU TARSASAG;CENTRE FOR RENEWABLE ENERGY SOURCES AND SAVING FONDATION;Huazhong Agricultural University;IFEU - INSTITUT FUR ENERGIE UND UMWELTFORSCHUNG HEIDELBERG GMBH;TUZETKA;CONSIGLIO NAZIONALE DELLE RICERCHE;UNIVERSITAT DE BARCELONA;AGRICULTURAL UNIVERSITY OF ATHENS;FACULDADE DE CIENCIAS E TECNOLOGIADA UNIVERSIDADE NOVA DE LISBOA;Indian Institute of Technology Delhi;ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA;UNIVERSITAT DE LES ILLES BALEARS;ABERYSTWYTH UNIVERSITY;CONSIGLIO PER LA RICERCA IN AGRICOLTURA E L'ANALISI DELL'ECONOMIA AGRARIA;UNIVERSIDAD POLITECNICA DE MADRID;B.T.G. BIOMASS TECHNOLOGY GROUP BV";"IT;IE;UK;AR;HU;EL;CN;DE;BE;ES;PT;IN;NL";/BIO;1;0;0;1;0;0 108604;330008;Arab Overseas Voting;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IEF;FP7;Overseas voting among Arab migrants in the EU;2013-09-01;2015-10-10;;"The research project ‘Arab Overseas Voting’ aims to contribute to the academic literature and policy discussion on overseas voting by drawing the attention on Arab migrant communities in the EU participating in the elections of their country of origin. It adopts an interdisciplinary and comparative approach that builds on historical and current contrasts between two major Arab labour sending countries (Tunisia and Morocco) and between two key EU receiving countries (France and Italy). Overseas voting is a worldwide trend. It is considered as a migrants’ right, and as contributing positively to democratization and development. However, the academic literature on overseas voting is still at an initial stage, in particular in Arab and African countries. The context of the project is that of momentous political changes in the Arab World, and increasing migration flows between North Africa and the EU since two decades. The general objective of the project is to assess why and how states enfranchise non-resident citizens, and under which conditions and for what purposes the latter participate in elections of their country of origin. In a policy perspective, the project aim to assess if, and under which conditions, overseas voting should be included in common migration policy frameworks, including the EU Global Approach to Migration and Mobility (GAMM). The project responds to EU demands to further investigate the governance of migration, in particular temporary migration; and social and political changes in Arab countries, in particular empowering young generation in context of political transition. With the aim of fulfilling such objective, ‘Arab Overseas Voting’ will pursue the following interrelated research objectives: patterns for adopting overseas voting; extensive versus restrictive voting rules; voters’ turnout; and voting behaviour, with a focus on age, gender, legal status differences.";261384,6;261384,6;FP7-PEOPLE-2012-IEF;/MC-IEF;FONDATION NATIONALE DES SCIENCES POLITIQUES;FR;;;/SCI;1;0;0;1;0;0 108857;609391;AREUS;ONG;FP7-NMP;FoF.NMP.2013-1;FP7;Automation and Robotics for EUropean Sustainabile manufacturing;2013-09-01;2016-08-31;http://www.areus-project.eu/;"European Factories of the Future will have to be smart and green: • SMART: high performance, reconfigurable, adaptive and evolving factories based on robotic technologies , • GREEN: reduced ecological footprint through a more efficient use, at factory level, of material and energy resources. Industrial Robotics is the strategic technology needed to keep the European Manufacturing leading edge, unfortunately it is intrinsically energy intensive, and its massive adoption compromises factories’ sustainability. The AREUS project objective is to overcome this limitation providing an innovative integrated technology and engineering platform, intrinsically interdisciplinary, modular and configurable based on four innovations: 1. An integrated set of Energy Consumption reduction technologies (R-ECO) based on a novel factory electrical power supply system to exchange, harvest, store and recover energy at factory level improving the use of renewable energy sources 2. A Robotic production systems Integrated Design and simulation environment (R-ID) for the eco-efficient design of robotic plants focused on the simulation of energy flows under a co-evolving product-process-robotic production systems approach 3. A Robotic manufacturing processes OPTimization environment (R-OPT) for the optimal sustainable production scheduling under a control engineering approach 4. LCA methods(R-LCA) to assess and optimize both environmental and economic costs linked with the flows of Material, Energy and Waste (MEW) of co-evolving products and processes realized with robotic production systems These building blocks will enable the modular and scalable/progressive development of singularly optimized sustainable robotic manufacturing applications (or the re-adaptation of existing production facilities) and will be demonstrated on 7 industrial case studies for their future exploitment.";6003008,91;3680000;FP7-2013-NMP-ICT-FOF(RTD);/CP-TP;UNIVERSITA DEGLI STUDI DI MODENA E REGGIO EMILIA;IT;"RIGAS TEHNISKA UNIVERSITATE;DELFOI OY;Delfoi GmbH;DANFOSS A/S;DAIMLER AG;ENGROTEC - CONSULTING GMBH;DANMARKS TEKNISKE UNIVERSITET;SIR SPA;KUKA ROBOTER GMBH;SIEMENS AKTIENGESELLSCHAFT;CHALMERS TEKNISKA HOEGSKOLA AB";"LV;FI;DE;DK;IT;SE";/SCI;1;0;0;1;0;0 105684;298167;REGIO_SPIN;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IEF;FP7;REGional Innovation pOlicy, knowledge Spillovers, Productivity, and INstitutions;2013-09-02;2015-09-01;;"The main aim of the REGIO_SPIN project is that of increasing the capacity of policy makers to design appropriate regional innovation policies in the European Union (EU). Regarding innovation policies, a paradigm shift in regional policy has occurred over the last decade in the EU, bringing innovation at the core of the regional agenda. The availability of Structural Funds, as the instrument for the EU cohesion policy, has provided regions substantial resources for innovation policy. The emphasis on the contextual nature of policy has led towards a differentiated territorial innovation policy approach or place-based policies also in EU regional policy. In fact, regional policies are still far away from being place-based: they are often similar and based on policy imitation of 'best practices’. Furthermore, their effectiveness has been questioned. Some key questions arise: Is the region the optimal scale for innovation policy? Do regions have the necessary institutional capability to manage innovation policy? Are regional institutions learning? According to which criteria policies encouraging University-Industry linkages should be designed? These are questions which go at the hearth of the place-based approach of the EU cohesion policy. The REGIO_SPIN project proposal aims to respond to these questions on the ground of empirical evidence. It will take an interdisciplinary perspective bringing together policy-oriented research with the geography of innovation and system of innovation, and the role of institutions. The empirical analysis, covering the European regions in several countries, is divided into three objectives: i. To explore the relationship between quality of the institutions and innovation policy impact; ii. To explore the extent to which policy leads to institution building; and iii. To explore the connection between different the nature of University-Industry linkages and types of Regional Innovation Systems.";209033,4;209033,4;FP7-PEOPLE-2011-IEF;/MC-IEF;LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE;UK;;;/SCI;1;0;0;1;0;0 99253;276562;CareMig;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-IEF;FP7;Caring Labour in a Migrating World;2011-09-01;2013-08-31;;"The position of migrant workers employed in European care systems is defined and shaped by the intersection and interrelation of national social policy and migration regimes embedded in specific economic, political and cultural contexts. The combination of the researcher’s background and knowledge of care and migration and the substantial expertise of the host institution in comparative studies of care in Europe will enable an interdisciplinary and multi-national analysis of the position of migrant workers in European care systems. The two contextual backgrounds and the complementary methodological expertise of the partners in Critical Discourse Analysis (researcher) and Comparative Case Studies Analysis (the host institution, in particular the mentoring group) will allow the partners to develop a new methodological and analytical conceptualisation to study the moral, social, economic, political and cultural context of caring, in which migrants work, by investigating both national policy regimes and people’s reflections on their work trajectories. This project will adress at least two main issues of the future of European societies: Ageing societies have been identified as one of the main challenges for Europe in the Lisbon 2020 strategy and labour migration has been described as important measure to tackle shortcomings in markets. Apart from the politically, economically and socially significant investigation of the position of migrant care workers this cooperation will foster a novel approach in the study of the intersection of care regimes and migration regimes which can furthermore act as a tool for important future investigations combining political, economic, social and cultural perspectives. Both the research community (in the field of care and migration studies and beyond) and policy makers will be able to learn and benefit from the outcomes of this cooperation.";168985,6;168985,6;FP7-PEOPLE-2010-IEF;/MC-IEF;UNIVERSITEIT UTRECHT;NL;;;"/EMP;/EDU;/NET";1;0;0;1;0;0 97629;251759;EXTRALEAD;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IEF;FP7;Extraordinary Leadership and Radical Change in Democracy;2011-09-01;2013-08-31;;"This project aims to study how radical change in democracy is effectuated by political leadership. In the classical liberal view, democracy is associated with ordinary institutional processes, juridical continuity, entrenched interest groups, extensive de-politicization, and gradual change. But democracies do not only develop in evolutionary manner; they also experience breaks and undergo new institutional beginnings. This project is motivated by the observation that such radical changes in democracy often originate from “extraordinary” individual leaders, able to disturb normal politics and provide new beginnings. I seek to explain the parameters of such leadership, develop a model of its workings, and test this model against empirical evidence. In addition, I also aspire to build a scholarly network for the study of political leadership in the contemporary European context in a systematic and theoretically sophisticated way. This MC Fellowship will be hosted by the European University Institute and supervised by Prof. Peter Mair, an established scholar in the field of comparative politics. Working within the EUI environment, this project will allow me to achieve my major training and research goals which are the improvement of scientific expertise and research skills; the interdisciplinary transfer of knowledge; and the establishment of a broad scholarly network for the further study of political leadership in Europe. Being already an experienced researcher, this project would further enhance my individual competences and advance my standing as an independent scholar within the European research community. To the extent that today there is a growing need for studying the role of political leaders able to undertake radical constitutive changes in our contemporary democracies, the proposed research would greatly contribute to EU-based production of scientific excellence in an important area, thus supporting the further development of the European Research Area.";222053,2;222053,2;FP7-PEOPLE-2009-IEF;/MC-IEF;EUROPEAN UNIVERSITY INSTITUTE;IT;;;"/SCI;/EDU;/ITT";1;0;0;1;0;0 92027;238409;ENHANCE;ONG;FP7-PEOPLE;FP7-PEOPLE-ITN-2008;FP7;European Research Training Network of “New Materials: Innovative Concepts for their Fabrication, Integration and Characterization”;2009-10-01;2013-09-30;;The multi-site European initial training network – “ENHANCE” – “New Materials: Innovative Concepts for their Fabrication, Integration and Characterization” will be established to deal with the mid and long term issues of concern to the European industry encompassing the whole spectrum of functional materials for microelectronics, nano-electronics, data storage, photovoltaic, with emphasis on emerging nano-technologies. This network consisting of 3 academic groups from chemistry 1 from physics, 3 from Material Science and Engineering and 1 industrial partners from 6 different countries of Germany, Finland, Netherlands, Italy, Denmark and Austria. Despite the exceptional importance of thin film processing of many new materials and their integration in emerging nanotechnologies, there is no systematic interdisciplinary training of students in the traditional courses of chemistry, materials science and engineering. ENHANCE aims to close this gap by combining the classical knowledge of chemistry, materials science, physics and engineering i.e. the knowledge of precursor molecules, materials properties, study of physical phenomena, to electronic devices and circuit integration. The training of ENHANCE fellows will be based on a structured 3 year academic curriculum, including, generic skills workshops and on-site research training at the state of the art laboratories, facilities under clean room conditions and a training at the industrial laboratories. This will provide the young scientists with necessary in-depth knowledge in materials synthesis and thin film processing as well as experimental skills in operating the instruments and analytical skills in different materials characterization techniques. The training concludes with European doctoral examination and will be reviewed by external experts in the field and their remarks will be addressed during the final disputation.;3697708,73;3697708,73;FP7-PEOPLE-ITN-2008;/MC-ITN;RUHR-UNIVERSITAET BOCHUM;DE;"TECHNISCHE UNIVERSITAET WIEN;HELSINGIN YLIOPISTO;FORSCHUNGSZENTRUM JULICH GMBH;TEKNOLOGISK INSTITUT;UNIVERSITA DEGLI STUDI DI PADOVA;TECHNISCHE UNIVERSITEIT EINDHOVEN;AIXTRON AG";"AT;FI;DE;DK;IT;NL";"/SCI;/EDU";1;0;0;1;0;0 109938;618143;ANALYSIS;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-CIG;FP7;Analysis of Natural Language for Real World Applications;2013-09-01;2018-08-31;;"Natural language understanding, information extraction, and machine translation are critical for human-machine interaction and key technologies in many everyday applications (e.g. search engines, mobile devices, robots). Natural language understanding systems transform spoken language or written texts into syntactic and semantic structures. Critically, these systems need to be able to work flexibly on many different text genres. A critical challenge for current syntactic analyzers in real-world applications is to adapt flexibly to different language domains. This problem arises because current syntactic analyzers are trained primarily on syntactically annotated newspaper texts. In particular, the major syntactic resource for training syntactic analyzers in English is an annotated text collection called the Penn-Tree Bank. The Penn-Tree Bank contains texts from only one genre that is economic news. However, the syntactic analyzers are applied to a wide range of text genres such as emails, newsgroups, blogs, consumer reviews, newspapers with mostly non-economic text, spoken language etc. When applied to these texts the error rate doubles. As a result of a doubled error rate the syntactic analyzer assigns the wrong syntactic structures to the input sentences. In other words, it confuses the subject and object in a sentence. Therefore it is no longer able to answer the critical questions in natural language understanding: Who does what to whom and why and when. For real-world applications this means that the robot may fail to understand the instructions or commands posed by the customer. The aim of this proposal is to reduce this gap and to provide techniques that obtain a higher accuracy and allow the adaptation to out-of domain genres in an easy and economically acceptable way. Further, in an interdisciplinary and innovative fashion, we will combine syntactic analysis with related analysis techniques from the field of speech recognition.";100000;100000;FP7-PEOPLE-2013-CIG;/MC-CIG;THE UNIVERSITY OF BIRMINGHAM;UK;;;/LIF;1;0;0;1;0;0 98887;273431;wasp fights;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-IEF;FP7;Metabolomics and contest behaviour in parasitoid wasps;2011-09-05;2013-09-04;;"Animal contests are widely studied by animal behaviourists and behavioural ecologists and there is a well developed framework for evaluating their functional significance. Parasitoid wasps in the family Bethylidae have proven ideal organisms to test predictive models (all of the predicted major influences on contest outcome-fighting ability, prior ownership and the way that individuals value possession of the contested resource - have now been successfully explored) and also in linking contests to other areas of basic (e.g. clutch size) and applied (e.g. biological pest control) areas of animal behaviour study. The link between nutritional/physiological state and contest behaviour has rarely been fully explored. The purpose of this proposal is to evaluate a range of nutrients derived from diverse food sources (nectar and the parasitoid’s host) and their influences on contest behaviours and outcomes. It is expected that particular nutrients may affect contest ability (termed Resource Holding Potential) whereas others may influence the value of the resource to a contestant. The relative importance, and interactions between these contrasting effects, will be explored. Identification and manipulation of key nutrients (proteins, lipids, carbohydrates and other metabolites) will be achieved by metabolomic analysis and other analytical and biochemical methods. The influence of nutritional state on contest behaviour will be assessed by behavioral observations. The cost of fighting behavior as influenced by nutritional state will be evaluated by real–time respirometry. The interdisciplinary approach of the proposed project will provide training opportunities in a range of modern techniques new to the researcher (metabolomics, NMR spectroscopy, biochemical methods) whereas will provide a new dimension to the understanding of dyadic animal contests by investigating the effect of variation in nutritional state between competing individuals";201049,6;201049,6;FP7-PEOPLE-2010-IEF;/MC-IEF;THE UNIVERSITY OF NOTTINGHAM;UK;;;"/EMP;/EDU;/NET";1;0;0;1;0;0 109663;327195;SIFT;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IEF;FP7;Symmetry Investigations in Flavour Theories;2014-09-01;2016-08-31;;"Flavour remains a deep puzzle in elementary particles. The Standard Model (SM) describes most data - but observations and theoretical reasons guarantee there is physics beyond. Why 3 generations in each family, and masses spanning over 10 orders of magnitude? Why is the mixing of quarks and leptons so different? Flavour puzzles go beyond the SM, with extensions like supersymmetry constrained to very specific flavour structures. These strongly imply underlying physics addressing flavour. Symmetries are extremely important in elementary particles. Unsurprisingly they are promising to understand flavour. Family symmetries relate generations, and can explain flavour in the SM and in extensions. Experimental effort is led by the LHC, recently discovering a particle likely to be the Higgs boson, searching for supersymmetry and probing flavour in LHCb. Increasingly precise neutrino experiments Daya Bay and RENO observed the 3rd mixing angle. Dedicated experiments probe rare processes such as neutrinoless beta decay or muon conversion. Cosmological observations test dark matter (likely to be an unobserved particle), the matter asymmetry of the Universe quantitatively requires a mechanism linked to new physics (such as leptogenesis) and Big Bang Nucleosynthesis is sensitive to SM modifications. In association with the experimental effort, theory is fundamental: to guide searches and to understand results. This proposal seeks the fundamental Theory of Flavour - possibly an ambitious supersymmetric unified theory with a family symmetry. It is fundamental to thrive on the abundance of data to guide theory in an integrated interdisciplinary way. Taking a broader view of flavour topics may lead to high impact breakthroughs from new approaches. Overall the project is expected to significantly expand the research profile of the fellow and increase the total impact of his contributions, therefore fully consolidating him to a level of full professional maturity.";309235,2;309235,2;FP7-PEOPLE-2012-IEF;/MC-IEF;UNIVERSITY OF SOUTHAMPTON;UK;;;/SCI;1;0;0;1;0;0 104372;302834;AvOri;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IEF;FP7;Beyond the Frontiers of Latin Christendom: The Avignon Papacy and the East;2013-02-01;2015-01-31;;"This research conjugates the history of the Avignon Church and the history of East West relations in the Late Middle Ages, shedding new light on the intellectual debates that developed within the Avignon Curia concerning Greeks, Armenians, Mongols, and Muslims. Despite an increasing scholarly interest in these research areas, studies on the Avignon Papacy have been characterized by an overwhelmingly local approach, whereas the relations of the medieval Papacy with different Eastern populations have not been sufficiently integrated within a comprehensive investigation on the Orient. This research aims to fill the gaps in the scholarly literature by examining how intellectual debates that developed within the Avignon Curia contributed to the shaping of Western ideas about the East. Based on the scrutiny of diplomatic sources, theological treatises, and travel reports, the study will shed light on the Western perception of the East in the Late Middle Ages from the perspective of intellectual history. Relying on comparative and interdisciplinary research methods, it will produce a comprehensive overview of the cultural reception of the Orient by the Avignon Curia, centered on the shaping of ideas about four major populations. The results will advance our understanding of the intellectual and political history of the Avignon Papacy through placing it for the first time in a wider, transnational context. The focus on the fourteenth century raises issues of continuities and discontinuities between medieval and modern European expansion. By applying the analytical category of Frontier to the Avignon context it will be possible to establish direct links with later European expansion into the New World and measure the success and endurance of medieval theoretical models developed by Roman Catholic Church. Thus, the proposed research will make key contributions to intellectual history, cultural history, history of inter-confessional relations, Church history and religion.";193594,8;193594,8;FP7-PEOPLE-2011-IEF;/MC-IEF;ECOLE DES HAUTES ETUDES EN SCIENCES SOCIALES;FR;;;/SCI;1;0;0;1;0;0 103753;298741;MicPLASMAS;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IIF;FP7;Microscopic Plasma Sources: Novel Diagnostics and Circuit Integration;2012-08-20;2013-08-19;;"It is proposed that Lawrence J. Overzet (LJO), Professor and Assoc. Depart. Chair of Electrical Engineering at The Univ. of Texas at Dallas, move to work with R. Dussart, P. Lefaucheux and their team at CNRS-GREMI / Polytech Orleans for 12 months. The work will focus on micro-plasma source diagnostics and development. In particular, the team will research novel and quantitative diagnostics of micro plasma sources (MPSs) and Micro-Cathode Sustained Discharges (MCSDs). The objective will be to develop MPSs and MCSDs as sources of beneficial chemical species and as tools for the abatement of detrimental chemical species. The longer-term goal is to integrate electronic circuitry with the MPSs and MCSDs to add new capability as well as control. Combining skills and knowledge for one year will greatly increase the progress in this important and interdisciplinary area of plasma science, as well as solidify a long-term international collaboration on this topic. Already, the group at GREMI is fabricating micro-plasma source arrays in silicon. LJO has needed expertise on Si fabrication and plasma diagnostics which will help to springboard this research to world leading level. Therefore the goals of the project are: [1] The transfer to GREMI of Radio Frequency diagnostics, including training on and further development of the techniques, as well as use in diagnosing MPSs and MCSDs; [2] The establishment at GREMI of FTIR diagnostics of MPSs and MCSDs by combining LJO’s expertise and GREMI equipment (new but presently unused); [3] Joint research using UV-Visible Optical Spectroscopic diagnostics of MPSs and MCSDs; [4] Joint research on integrating electronic devices with MPSs and MCSDs; and [5] Outreach activities to Polytech Orleans students as well as local high school students along the lines of the “Marie Curie Ambassador” model. Each goal is expected to lead to results that are high impact.";134548,2;134548,2;FP7-PEOPLE-2011-IIF;/MC-IIF;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FR;;;/SCI;1;0;0;1;0;0 185381;336536;FUNCSPECGEN;ONG;FP7-IDEAS-ERC;ERC-SG-LS8;FP7;What is the engine of biodiversity? Comparative and Functional Speciation Genetics in the Post-genomic Era;2014-04-01;2019-03-31;;"More than 150 years after the seminal works of Charles Darwin on speciation, we are beginning to unravel the genetic underpinnings of the splitting process (Ellegren H [..] JBW Wolf, Nature, in press). The genomic revolution is progressing at full speed, and for the first time in history we are equipped with the necessary tools to investigate the genomic architecture of speciation at base-pair resolution in any organisms of our choice. When integrated to the mature theoretical framework of the evolutionary sciences, this wealth of genome-scale data will produce fundamental insights into the processes governing adaptation and speciation. Here, I identify a novel evolutionary model system - crows and ravens of the genus Corvus - and demonstrate its potential for speciation genetic and functional genomic research. Central to this system is the phylogenetically independent recurrence of a pied colour-pattern in several species that stands in contrasts to the predominant all-black plumage in the clade. Building on the idea that colour polymorphism can promote speciation through sexual selection, I choose a number of black and pied species pairs that can be positioned along a time line representing different stages of the speciation process. This comparative framework is unrivalled in its setup and is uniquely suited to study the genetics of speciation across different stages of species divergence. It also provides a promising entry point to the fascinating theme of parallel evolution. This research program is among the first to harness the possibilities of the post-genomic era in a wild organism. Using a combination of population- and phylo-genomic approaches, single sperm sequencing, experimental work in a breeding population, systems biology approaches and in situ mRNA quantification at cellular resolution, this interdisciplinary program covers novel ground in the nascent field of functional avian genomics and pushes the boundaries of speciation genetic research.";1494300;1494300;ERC-2013-StG;/ERC-SG;LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN;DE;UPPSALA UNIVERSITET;SE;"/BIO;/LIF";1;0;0;1;0;0 98380;276750;Metasensors;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-RG;FP7;Metabolic sensor proteins that couple essential cellular processes and primary metabolism;2011-03-01;2015-02-28;;"How are we what we eat? How are essential cellular processes coordinated at the level of protein activity in response to nutritional changes? This is the broad question my research seeks to understand. Metabolic pathways building the cell bricks are extensively described. By contrast, our understanding of the molecular mechanisms driving cell-wide processes is recent and incomplete. This explains why the regulatory links between these cellular processes and primary metabolism are largely unexplored. State of the art methods, in particular in cell biology, now provide the means to address this fundamental question. Investigating these connections are best carried out in simple well defined systems. My research uses the model bacterium Bacillus subtilis. It is a Gram positive rod-shaped bacterium that is genetically amenable. In this project, we propose candidate and innovative large-scale approaches to identify and characterize metabolic sensors at the heart of these regulations. First, we will characterize a candidate protein that is expressed in the same operon as a metabolic enzyme and which absence affects cell division. We will also take advantage of this time to setup a high-throughput fluorescence microscopy workflow and transfer tools from my post-doctoral laboratory, hire students and formalize collaborations in Europe and the United States. Second, the main part of this project will concentrate on the identification and the characterization of new proteins coupling morphogenesis, division and chromosome dynamics to carbon and nitrogen metabolism. An interdisciplinary approach combining modern techniques in fluorescence microscopy, genetics, genomics, bioinformatics, biochemistry and automation will be used to study these metabolic sensors. Understanding the connections between metabolism and cell-wide processes will yield fundamental knowledge on the global functioning of the bacterial cell but also provide basis for new antibacterial drugs development.";100000;100000;FP7-PEOPLE-2010-RG;/MC-IRG;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FR;;;/SCI;1;0;0;1;0;0 91921;234990;"""""""PICTURING GENDER""""""";ONG;FP7-PEOPLE;FP7-PEOPLE-IEF-2008;FP7;"""""""Picturing 'gender'. Visual translation, popularisation and contesting of a key discourse in the New Europe""""""";2009-09-01;2011-08-31;;The interdisciplinary project “Picturing ‘gender’: Visual translation, popularisation and contesting of a key discourse in the New Europe” (PICTURING GENDER) investigates examples of translating and adopting the new philosophical concept “gender” into popular visual culture in various European cultural contexts. Within this larger framework, the project comprises the following specific objectives: • to collect examples of visual adoptions of the gender concept • to analyse these images with respect to the meanings staged in them and how they interlink with meanings created by visual culture, set in motion by other social agents • to investigate the reception histories these images set in motion. • to compare examples in various European countries with each other and to investigate the cultural conditions of their adoption • to re-evaluate the productivity of the use of the concept of gender as well as the meanings created in this way. Hence the quality of PICTURING GENDER lies in its original view of the popularisation of the gender concept within Europe. The innovative approach consists in focusing especially on images and visual worlds into which this concept is translated. This focus on the image and the specificity of its communicative powers makes it possible to access the complex reworking of the popular imaginary that goes along with the dissemination of gender discourse. In this way the more involuntary, hidden creations of meaning concerning gender and sexual difference as well as unintentional linkages with other popular discourses, which remain closed to other perspectives, become graspable. The relevance of the project for current political culture in Europe therefore lies especially in this emphasis on the broader popular as well as artistic signification processes concerning a key notion of current emancipation strategy and on the public life of the images created in this way.;;218490,62;FP7-PEOPLE-IEF-2008;/MC-IEF;UNIVERSITA DEGLI STUDI DI VERONA;IT;;;"/SCI;/EMP";1;0;0;1;0;0 109160;329652;GRASSLANDS;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IIF;FP7;The evolution of the Grassland biome: exploring past events to predict future scenarios;2013-08-01;2015-07-31;;Knowledge of the evolution of the grassland biome throughout the Earth's environmental history is important for the reconstruction of links between diversification/extinctions events and climate. Biomes are now being impacted by anthropogenic environmental change on an unprecedented scale, and one mean of understanding how component species will react is to study the effects of past environmental changes. Hence, understanding the evolutionary history of grassland ecosystems in the context of past biotic and abiotic changes is relevant to the way we will manage them under future environmental change. A new perspective on the history of the grassland biome is beginning to emerge from key developments in palaeontology and molecular phylogenetics that will be integrated interdisciplinary and multidisciplinary in the present project for the first time. GRASSLANDS aimed at understanding the timing and nature of grasslands' most important components, the grass (Poaceae) and daisy (Asteraceae) families, through the combination of fossil data, molecular phylogenetics and computational approaches. The potential contribution of GRASSLANDS to our understanding of the evolutionary history of these families and grassland ecosystems in general is significant and will certainly provide new insights into the rise of flowering plants as the dominant components of almost every terrestrial ecosystems.;231283,2;231283,2;FP7-PEOPLE-2012-IIF;/MC-IIF;ROYAL BOTANIC GARDENS KEW;UK;;;/SCI;1;0;0;1;0;0 109815;335040;DYNAMO;ONG;FP7-IDEAS-ERC;ERC-SG-PE3;FP7;"Dynamics and assemblies of colloidal particles under Magnetic and Optical forces";2014-01-01;2018-12-31;;"Control of microscale matter through selective manipulation of colloidal building blocks will unveil novel scientific and technological avenues expanding current frontiers of knowledge in Soft Matter systems. I propose to combine state-of-the-art micromanipulation techniques based on magnetic and optical forces to transport, probe and assemble colloidal matter with single particle resolution in real time/space and otherwise unreachable capabilities. In the first part of the project, I will use paramagnetic colloids as externally controllable magnetic inclusions to probe the structural and rheological properties of optically assembled colloid crystals and glasses. In the second part, I will realize a new class of anisotropy patchy magnetic colloids, characterized by selective, directional and reversible interactions and employ these remotely addressable units to realize gels and frustrated crystals (static case), active jamming and synchronization via hydrodynamic coupling (dynamic case). DynaMO project will power a basic experimental research embracing a variety of apparently different systems ranging from deterministic ratchets, viscoelastic crystals, glasses, patchy colloidal gels, frustrated crystals, active jamming, and hydrodynamic waves. The ERC grant will allow me to establish a young and dynamic research group of interdisciplinary nature focused on these issues and aimed at performing high quality research and training/inspiring talented researchers in innovative and challenging scientific projects.";1309320;1309320;ERC-2013-StG;/ERC-SG;UNIVERSITAT DE BARCELONA;ES;;;"/PSE;/ELM;/NNT";1;0;0;1;0;0 103322;302737;Met-IPBS;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IEF;FP7;Methane GeoMicrobiology in the Iberian Pyritic Belt Subsurface;2012-09-16;2015-01-04;;"The subsurface of both marine and terrestrial environments has been rising a lot of interest lately, more since it was shown that its biogeochemical cycles are more active than originally thought. The Iberian Pyritic Belt (IPB), one of the largest sulfide deposits on Earth, is situated the southwestern Spain. It is the source of the highly acidic Tinto River, maintains a low pH (mean 2.3) and a high metal concentration, especially Fe(III), along almost its whole length. The high acidity predates the extensive mining of this area, being caused by the activity of the chemolithotrophic microbial community found in the subsurface, whose main source of energy is the oxidation of the pyrite with release of Fe(III) and sulfate. The geomicrobiology of the IBP subsurface is poorly studied. A recent drilling project has shown the existence of methane deep in the subsurface, and, together with the geochemical data, it points toward microbial methanogenesis. This proposal aims toward a multidisciplinary and interdisciplinary approach to study the geomicrobiology of methane production/consumption in the IPB subsurface. A broad suite of tools from geology, microbiology, geochemistry, mineralogy and molecular ecology will be used to achieve the following: (i) to determine where in the subsurface are methanogenesis and methanotrophy taking place; (ii) to determine the methane sources and sinks; (iii) to identify and characterize the microorganisms involved into the methane cycling, their energy sources and electron acceptors, and the metabolic pathways employed; (iv) to characterize the microbe-mineral interactions associated with the methane cycling, and (v) to develop a geomicrobiological model for the methane generation and consumption and its relevance for the C cycle in subsurface. This proposal is in line with the international trend in research toward the understanding of the subsurface environments, and it will contribute to the excellence of the European Research Area.";176053,2;176053,2;FP7-PEOPLE-2011-IEF;/MC-IEF;AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS;ES;;;/SCI;1;0;0;1;0;0 95640;258509;MULTIMATE;ONG;FP7-IDEAS-ERC;ERC-SG-PE8;FP7;A Research Platform Addressing Outstanding Research Challenges for Nanoscale Design and Engineering of Multifunctional Material;2010-09-01;2015-08-31;;"'Nanoscale engineering is a fascinating research field spawning extraordinary materials which revolutionize microelectronics, medicine,energy production, etc. Still, there is a need for new materials and synthesis methods to offer unprecedented properties for use in future applications. In this research project, I will conduct fundamental science investigations focused towards the development of novel materials with tailor-made properties, achieved by precise control of the materials structure and compostition. The objectives are to: 1) Perform novel synthesis of graphene. 2) Explore nanoscale engineering of 'graphene-based' materials, based on more than one atomic element. 3) Tailor uniquely combined metallic/ceramic/magnetic materials properties in so called MAX phases. 4) Provide proof of concept for thin film architectures in advanced applications that require specific mechanical, tribological, electronic, and magnetic properties. This initative involves advanced materials design by a new and unique synthesis method based on cathodic arc. Research breakthroughs are envisioned: Functionalized graphene-based and fullerene-like compounds are expected to have a major impact on tribology and electronic applications. The MAX phases are expected to be a new candidate for applications within low friction contacts, electronics, as well as spintronics. In particular, single crystal devices are predicted through tuning of tunnel magnetoresistance (TMR) and anisotropic conductivity (from insulating to n-and p-type). I can lead this innovative and interdisciplinary project, with a unique background combining relevant research areas: arc process development, plasma processing, materials synthesis and engineering, characterization, along with theory and modelling.'";1484700;1484700;ERC-2010-StG_20091028;/ERC-SG;LINKOPINGS UNIVERSITET;SE;;;"/PSE;/EAR";1;0;0;1;0;0 99970;283201;EMBRACE;ONG;FP7-ENVIRONMENT;ENV.2011.1.3.2-1;FP7;Building Resilience Amongst Communities in Europe;2011-10-01;2015-09-30;http://www.embrace-eu.org/;"In an interdisciplinary, socially inclusive and collaborative context, emBRACE aims to improve the framing of resilience in the context of disasters in Europe. It will develop a conceptual and methodological approach to clarify how the resilience capacity of a society confronted with natural hazards and disasters can be characterized, defined and measured. On the basis of a systematic evaluation of the widest literature base, the project will first elaborate an initial conceptual framework. Disaster footprints and a review of current data gaps and challenges for human impacts and development databases in providing resilience data on regional and national levels will help inform indicator development. These will then be tested and ground truthed by means of 6 well-chosen case studies across Europe exposed to different natural hazards, situated in different governance settings and socio-demographic-economic contexts. Resilience will be contextualised through the application and evaluation of newly developed indicators and models, and will contribute to reformulation and adaption of the conceptual framework. emBRACE will considerably advance the methodologies for evaluating, modeling and assessing resilience of different actors. emBRACE will be methodologically rich, drawing on partner expertise across the research methods spectrum. It will apply these methods across scales from local to European. Stakeholders and experts will be incorporated into knowledge-sharing groups. There will be ongoing engagement with these stakeholders alongside programmed consultations during the development of the framework and model, case study work, and the reshaping of concepts, guidelines and database requirements for disasters and societal resilience. A key difference in emBRACE is the seeking out of people and groups not normally included in such fora; not as subjects of research but as partners in research and experts in their own right.";4244772,98;3243423;FP7-ENV-2011;/CP-FP;UNIVERSITE CATHOLIQUE DE LOUVAIN;BE;"SEI OXFORD OFFICE LIMITED*STOCKHOLMENVIRONMENT INSTITUTE OXFORD OFFICE SEI LTD;THE UNIVERSITY OF READING;UNITED NATIONS UNIVERSITY;HELMHOLTZ-ZENTRUM FUER UMWELTFORSCHUNG GMBH - UFZ;UNIVERSITY OF NORTHUMBRIA AT NEWCASTLE;UNIVERSITY OF YORK;ACCADEMIA EUROPEA DI BOLZANO;EIDGENOESSISCHE FORSCHUNGSANSTALT WSL;KING'S COLLEGE LONDON;MIDDLE EAST TECHNICAL UNIVERSITY";"UK;JP;DE;IT;CH;TR";/ENV;1;0;0;1;0;0 98365;277038;SYMASC;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-RG;FP7;Bacterial Symbiosis in Ascidians;2011-04-01;2014-09-30;;'The study of invertebrate-microbial associations is emerging as a prominent field in marine biology and biotechnology, with vast implications that range from a fundamental knowledge of host ecology and symbiont biodiversity to the advanced understanding of natural products discovery and sustainable production. While considerable incentives exist to unravel the complex metabolic interactions between host invertebrates and symbiotic microbes, basic questions regarding the biodiversity and stability of these relationships remain unanswered. Here, I propose to advance our knowledge on the genetic diversity, spatio-temporal variability and functional significance of microbial symbionts in ascidians. First, I propose to characterize the diversity and host-specificity of ascidian-microbial symbioses by massively parallel 16S rRNA gene tag pyrosequencing and comparison of microbial community partitioning in ascidians at the inter- and intra-species levels. Secondly, I will describe the dynamics and fidelity of invertebrate-microbial relationships by documenting spatial and temporal fluctuations of bacterial and archaeal communities in ascidians, utilizing the sensitive DNA fingerprinting technique T-RFLP in conjunction with 16S rRNA gene libraries from pyrosequencing. Finally, I will provide the first assessment of the contribution of autotrophic and heterotrophic symbionts to host metabolism over time by quantifying the stress levels and reproductive success of the host. The multi-scale and interdisciplinary research approach suggested here will provide for the first holistic account of host-symbiont interactions between ascidians and microbes.';87500;87500;FP7-PEOPLE-2010-RG;/MC-IRG;UNIVERSITAT DE BARCELONA;ES;;;/SCI;1;0;0;1;0;0 99417;273851;LARVDEVOPTI;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-IEF;FP7;"""Larval quality in oyster hatcheries: Effects of ocean acidification, temperature change and food availability on reproductive success and survival of the European flat oyster""";2011-08-16;2013-08-15;;"'The proposed research will investigate the effects of biological and physicochemical conditions on growth and development of the European flat oyster (Ostrea edulis) throughout its life cycle. Specific research objectives for this project are: 1. determine current causes of hatchery instability in broodstock conditioning and larval productivity, including potential effects of ocean acidification and temperature change on larval development in O. edulis; 2. optimize ecophysiological conditions for O. edulis larval development in a commercial-scale hatchery to allow sufficient production of spat for expansion of the flat oyster aquaculture industry; 3. identify coastal grow-out sites on the Bohusian coast (at least 3) that are suitable for aquaculture operations in order to optimize the growth of O. edulis to marketable size. The research links together multiple research groups and industry partners in optimizing the cultivation of flat oysters. Studies will utilize established infrastructure at the Sven Lovén Marine Sciences Center of Gothenburg University, the Danish Shellfish Centre, and the commercial hatchery Ostrea Sverige. The Applicant will be working with researchers at these institutions to apply interdisciplinary expertise to the project objectives. This proposal combines aspects of developmental biology, marine ecology, chemical and physical oceanography, and geography, and the application of these fields to answering key questions about oyster larval development and improvement of aquaculture processes. A lack of understanding of factors affecting larval and juvenile survival currently curtails hatchery production of O. edulis in Sweden, thereby impeding expansion of a European flat oyster aquaculture industry in northern waters. Data derived from the project will be relevant to the effects of ocean acidification on natural populations, while also ensuring successful hatchery production to meet European market demand for high-quality cultured shellfish.'";193266,4;193266,4;FP7-PEOPLE-2010-IEF;/MC-IEF;GOETEBORGS UNIVERSITET;SE;;;"/EMP;/EDU;/NET";1;0;0;1;0;0 97679;260600;GLYCOHIT;ONG;FP7-HEALTH;HEALTH.2010.1.1-3;FP7;Glycomics by High-throughput Integrated Technologies;2011-01-01;2014-06-30;http://glycohit.eu/;"Protein glycosylation is a post-translational phenomenon that is involved in most physiological and disease processes including cancer. Most of the known cancer-associated glycobiomarkers were discovered individually using liquid chromatography and mass spectroscopy. Though valuable, there is room for improvement in these approaches for the discovery phase. There is also a critical need for innovative, rapid, and high-throughput (HTP) technologies that will translate the discovery of cancer-associated glycobiomarkers from basic science to clinical application. The GlycoHIT consortium brings a highly experienced, innovative and interdisciplinary team of researchers from Europe, China and USA representing academia, industry and clinical fields to significantly enhance some of the existing glycoanalytical technologies and to advance novel HTP glycoanalytical technologies beyond current state of the art. ? Microchip technology and novel partitioning methods will be exploited for nanoscale HTP separations of serum glycoproteins for analysis by HPLC or LC–MS. ? In parallel, lectin array technology will be radically improved by the innovative use of recombinant human lectins and lectin mimics derived by screening large phage displayed combinatorial libraries. ? Aptamer libraries will be exploited for identification of lectin mimics and development of a glycosignature platform ? Compatibility of the lectin/lectin mimic array technologies with novel label-free biosensors will be explored. Newly-developed technologies will be validated by analysis of serum samples from a variety of cancer patient cohorts and will be supported throughout by experimental interaction analysis, complex structural modelling and informatics. Effective project management, commercially-aware intellectual property management and targeted dissemination activities supplement the core science and ensure maximum impact for the project.";4874903,6;2993056,4;FP7-HEALTH-2010-single-stage;/CP-FP-SICA;NATIONAL UNIVERSITY OF IRELAND GALWAY;IE;"LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN;PINTAIL LTD;TSINGHUA UNIVERSITY;OSLO UNIVERSITETSSYKEHUS HF;AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS;KOKURITSU DAIGAKU HOJIN HOKKAIDO DAIGAKU;UNIVERSITE DE MONS;INSTITUT PASTEUR;UNIVERSITAETSKLINIKUM HEIDELBERG;KAROLINSKA INSTITUTET;AGILENT TECHNOLOGIES ISRAEL LTD;HUNAN UNIVERSITY;National Institute for Bioprocessing Research and Training Ltd;BRISTOL-MYERS SQUIBB COMPANY CORP";"DE;IE;CN;NO;ES;JP;BE;FR;SE;IL;US";/MED;1;0;0;1;0;0 99292;269442;THE RISE;ONG;FP7-IDEAS-ERC;ERC-AG-SH6;FP7;"Travels, transmissions and transformations in the 3rd and 2nd millennium BC in northern Europe: the rise of Bronze Age societies";2011-06-01;2016-05-31;;"Research problem: The 3rd and 2nd millennium was a period that saw major social and cultural transformations in Europe, from migrations and the introduction of metal (the Bronze Age) to new cultural identities and languages. As these two millennia were formative for Europe’s later history, these are hotly debated issues. However, they can now be resolved, at least in part, by the application of new science-based methodologies and the development of new interpretative frameworks. Aims and methodologies: The project does so by adopting an interdisciplinary methodological approach that combines science and culture. Isotope tracing in combination with recent advances in ancient DNA is employed to test human origins and movements during the two millennia, as well as the origin of wool and textiles. Lead isotope is adopted to trace the origin of copper. Based on this the project will document and explain the forging of new identities and new types of interaction during the 3rd and 2nd millennium BC in temperate northern Europe, but with implications for western Eurasia. Progress and originality: Accomplishment of front-line research results by combining archaeology with new developments in the natural sciences to produce new knowledge about the mobility of people, animals, things, ideas and technologies. This will allow a critical comparison of different types of evidence on mobility from DNA to strontium isotope analyses, and will lead to improved knowledge about the ways in which European regional cultures and identities were formed in the Bronze Age through interaction. Finally, the project will potentially change our understanding and thinking about human mobility as a key factor in cultural and social change.";2488264;2488264;ERC-2010-AdG_20100407;/ERC-AG;GOETEBORGS UNIVERSITET;SE;KOBENHAVNS UNIVERSITET;DK;/SOC;1;0;0;1;0;0 96055;255243;ECOLOGYOFMOVEMENT;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IEF;FP7;New approach to animal movement modeling combining ecological and cognitive sciences, with application to wildlife responses to infrastructure;2011-08-01;2013-07-31;;"Movement is the primary response of animals to spatiotemporal heterogeneity in ecological conditions. The consequences of movement for individual fitness, populations and ecological communities give this behavior a central place in ecological theory. Human activities alter both spatiotemporal variations in ecological conditions triggering movements (e.g. resource distribution) and availability of movement corridors (e.g. destruction of migration routes). An understanding of factors driving animal movements, affecting their mechanics, and characterizing the preferred travel routes is essential for ecological theory and to evaluate the impact of human activities on population dynamics and on the potential for human-wildlife conflicts. Due to recovering ungulate populations and increased road and rail traffic, ungulate-vehicle collisions represent an important source of conflict. These collisions lead to casualties, injuries and substantial economical losses. Due to poor knowledge of movement drivers and mechanics, mitigating measures currently taken to minimize the probability of collisions are often inadequate and inefficient. Despite the 10-year old call for a “behavioral ecology of ecological landscapes” (Lima & Zollner 1996), only limited information about cognitive mechanisms underlying movement is included in fundamental and applied ecology. During the past decades behavioral scientists have made important progresses in the understanding of animal spatial cognition and goal-oriented movements in laboratory settings. This project proposes a novel interdisciplinary approach to develop a mechanistic movement model integrating theory on space use from ecology in natural settings with theories from behavioral and cognitive sciences in the laboratory. Such model will have a broad range of applications in theoretical and applied animal movement ecology. We will use this model to identify risk areas for moose-vehicle collisions in Norway and guide mitigating actions.";204068;204068;FP7-PEOPLE-2009-IEF;/MC-IEF;STIFTELSEN NORSK INSTITUTT FOR NATURFORSKNING NINA;NO;;;"/SCI;/EDU;/ITT";1;0;0;1;0;0 109526;618112;IAM4MARS;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-CIG;FP7;Intelligent Automated Methods for Monitoring Agriculture with Remote Sensing;2013-08-01;2017-07-31;;"'Remote sensing images have been a significant information source for many different applications, especially for monitoring agricultural and environmental resources. Yet knowledge extraction from them is often performed by domain experts using heavily interactive computer-aided photo-interpretations due to lack of powerful automated methods. Improved spatial/spectral resolution in recent years provides details for precise monitoring, in expense of making the problem even more complicated. For monitoring agriculture in Europe, we will innovatively propose an unsupervised automated method (with limited interaction) based on advanced similarity criteria utilizing spectral/spatial characteristics and on manifold learning techniques for clustering large data sets of very-high resolution images. This will provide a fast and accurate approach for assessment of agricultural systems at the community level, which is currently done by expert image analysis. In addition, the research addressed here (novel similarity criteria harnessing different types of information and hybrid clustering), which will certainly contribute to the EU’s research excellence in remote-sensing and data mining, are expected to be advantageous for other remote-sensing applications, and also for clustering other large data sets. This will lead to interdisciplinary applications of the proposed study resulting in greater applicability beyond agricultural monitoring (which has already a broad application area encompassing whole EU, concerning about 9 million farmers and 140 million reference parcels). The CIG will integrate Dr. Taºdemir, an early career researcher with postdoctoral experience at EC Joint Research Centre (where he received the best young scientist award) and a PhD from Rice University, USA (where he received an award for contributions to graduate life), to establish his lab at Antalya International University, for research training and attracting talented individuals in the remote-sensing.'";100000;100000;FP7-PEOPLE-2013-CIG;/MC-CIG;ULUSLARARASI ANTALYA UNIVERSITESI;TR;;;/LIF;1;0;0;1;0;0 105743;308136;POLAFLOW;ONG;FP7-IDEAS-ERC;ERC-SG-PE2;FP7;Polariton condensates: from fundamental physics to quantum based devices;2012-11-01;2017-10-31;;"Polaritons are quantum superpositions of light and matter which combine appealing properties of both: the high coherence of photons and the strong interaction (non-linearities) of electrons. With the report of their Bose-Einstein condensation in 2006, they stand as one of the most exciting semiconductor-optical system of today. Given their peculiar character, they encompass different interdisciplinary areas of research which spans from the physics of phase transitions, critical phenomena and strongly-correlated systems (superfuidity, superconductivity, etc.) to various branches of quantum physics (quantum optics, quantum information, etc.), till the possibility of building polariton-based optical logics for implementation of optical circuits; all exciting realms yet to be explored. The majority of the outstanding findings reported have been realised in structureless samples with no, or random, potential barriers for polariton states. This proposal aims at developing the polariton physics in the presence of designed and controllable potential landscapes which will allow the observation and study of a new series of phenomena related to the system's reduced dimensionality and out-of-equilibrium character. Strong of several and complementary techniques to realize such potentials in microcavities, both in my institute and in partnership with leading growers worldwide, I will explore three phases of prospective physics in the framework where the polariton flow can be controlled, driven, localised and guided. First, I will study transport and interferometry. Then, these straightforward upgrades on the polariton state-of-the-art will be used to design elementary devices, such as polariton transistors (classical logic) or entangling devices (quantum logic). In a final phase, polariton lattices with controllable attributes will be used to study fundamental quantum phases from the superfluid to the Mott insulator, with prospects of realizing a polariton quantum simulator.";1482600;1482600;ERC-2012-StG_20111012;/ERC-SG;CONSIGLIO NAZIONALE DELLE RICERCHE;IT;"UNIVERSITY OF WOLVERHAMPTON;FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS;UNIVERSIDAD AUTONOMA DE MADRID";"UK;EL;ES";"/PSE;/SCI";1;0;0;1;0;0 90704;221323;ORGANOMETALLICSWITCH;ONG;FP7-PEOPLE;PEOPLE-2007-2-1.IEF;FP7;metal-carbene complexes for the synthesis of molecular switches and devices;2009-02-01;2011-01-31;;Considerable effort is currently being devoted to the miniaturization of electronic devices to the nanometer scale, ideally affording systems that operate on a molecular level. Chemist’s contribution to this research area has thus far concentrated on the preparation of organic OR inorganic materials. For example, purely metallic GaAs and GaP nanowires have been constructed for semiconductor applications. While these materials show excellent electron mobility properties, their tuning potential is rather low. In contrast, organic semiconductors such as conjugated oligomers or polymers display promising properties, though their electron carrier properties are intrinsically lower than that of metallic materials. Organometallic species comprising tunable organic ligand moieties and transition metal centers featuring an enhanced electron mobility may combine the advantages of purely inorganic and organic materials and are therefore expected to be particularly useful as molecular units for the fabrication of new electronic devices. The proposed research aims at identifying molecular switches based on mono- and multimetallic complexes and at their implementation in electronically active devices, thus creating intelligent materials. While organometallic chemistry dominates the highly synthetic first part of the project, the characterization and application of self-assemblies in molecular electronics clearly requires an interdisciplinary approach.;178163,71;178163,71;FP7-PEOPLE-2007-2-1-IEF;/MC-IEF;UNIVERSITE DE FRIBOURG;CH;;;"/SCI;/EDU";1;0;0;1;0;0 105414;317321;ChangingEmployment;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-ITN;FP7;The changing nature of employment in Europe in the context of challenges, threats and opportunities for employees and employers;2012-12-01;2016-11-30;http://www.changingemployment.eu;"Europe is today facing several major challenges. These go beyond the future of the euro and the instability of the financial system to some of the underlying issues concerned with the work activities that underpin the European economy. How can Europe retain manufacturing and production as restructuring and relocation towards lower-wage costs economies gathers pace? As demographic change lifts the proportions of older workers in society and in employment, how can Europe both maintain decent levels of pensions and provide decent jobs for younger workers? As cross-border migration becomes ever easier how can migrant workers be fully integrated and accepted into the European labour market? How can aspirations for decent jobs be squared with the nearly pan-European progression of precarious work? Europe’s future depends in large part on the answers it can provide to these questions within the context of the vision of a competitive, technologically-innovative economy bolstered by a high road social model that was captured in the Europe 2020 strategy. The aim of the ChangingEmployment programme is to train a cross-European and interdisciplinary network of policy-focused social scientists comprehensively skilled in understanding, analyzing, and responding to social and institutional employment changes. Overall, it will: 1.Explore, societal differences, national variations in employees’ experiences of working life. 2.Examine historic and changing relations between management and employees. 3.Develop a comparative understanding of the changing quality of work, organisation and employment in the context of the (above) changes. 4.Consider patterns and consequences of workplace inclusion-exclusion in relation to migration, employment and unemployment, shifting inequalities in terms of gender and ethnicity and the implications for older employees of new patterns of work and retirement. 5.Assess impact of the current economic retrenchment on these forms of employment in Europe";4062292,12;4062292,12;FP7-PEOPLE-2012-ITN;/MC-ITN;UNIVERSITY OF STRATHCLYDE;UK;"UNIWERSYTET WROCLAWSKI;KOZEP-EUROPAI EGYETEM;UNIVERSITE LIBRE DE BRUXELLES;UNIVERSIDAD DE OVIEDO;LONDON METROPOLITAN UNIVERSITY;UNIVERSITE D'EVRY-VAL D'ESSONNE;KATHOLIEKE UNIVERSITEIT LEUVEN;GOETEBORGS UNIVERSITET";"PL;HU;BE;ES;UK;FR;SE";/LIF;1;0;0;1;0;0 95629;254243;VIEWFROMHEAVEN;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IEF;FP7;A View from Heaven. Exploring the Potential of Remote Sensing Techniques to Study Spatial Patterns of Monastic Habitation on the East Bank of the Nile in Middle Egypt;2010-09-15;2013-08-14;;Early Egyptian monasticism played a defining role in the establishment of monastic life in Europe. However, our understanding of the history of the formation and organization of monastic life in Egypt itself is incomplete. Whereas monastic centres in northern and southern Egypt are being extensively studied, the important region of Middle Egypt has scarcely received scholarly attention. From AD 300-800, this area had a thriving Christian life and a large number of monastic settlements. On the east bank of the Nile, monks settled mainly in Pharaonic tombs and quarries in the chain of hills hugging the river. They adapted the spaces to their needs and established communities. Most of these dwellings are still relatively intact. Since written documentation is scarce, this archaeological material presents a unique opportunity to complete our picture of the formation and organization of early Egyptian monasticism. A comprehensive study is necessary to understand how and when this monastic landscape took shape. Why did it assume its specific spatial pattern and how did it function, locally and in a wider sense? To answer this composite question, I intend to acquire skills in the interpretation of satellite imagery for the localization of sites and Geographic Information Systems (GIS) for integrated spatial data processing. An innovative interdisciplinary approach is essential to establish the intra- and intersite patterns of these monastic habitations. In conjunction with historical research and field survey, a view from heaven through satellite remote sensing (RS) will draw a map of the monastic landscape as a starting point for innovative site location modelling analyses using GIS techniques. Known historical data will be projected upon this new contextual backcloth to generate a new understanding of the development of monasticism in Egypt.;220500;220500;FP7-PEOPLE-2009-IEF;/MC-IEF;KATHOLIEKE UNIVERSITEIT LEUVEN;BE;;;"/SCI;/EDU;/ITT";1;0;0;1;0;0 105404;312454;DISRUPTION;ONG;FP7-IDEAS-ERC;ERC-SG-SH5;FP7;"The Principle of Disruption. A Figure Reflecting Complex Societies";2013-01-01;2018-12-31;;'Disruption' is presented as a starting point for the analysis of formulas of societal self-description. Since the increasing susceptibility of complex societies to disruption cannot be managed solely by technology and the social sciences, it is necessary to develop a new form of cultural criticism which critically reflects on the interaction of societal sub-systems. Therefore, the objects to be studied are strongly repercussive narratives which construct political and socio-cultural coherence through the symbolic reintegration of disruptive incidents - e.g. terrorist attacks, rampage shootings, technical accidents, new diseases. The analysis of this poetics of social normalisation is intended to contribute to resolving the - for complex societies - constitutive problem of self-interpretation. The project is innovative in that it frees the concept of disruption from its restrictive use in media theory, reformulates it culturally and narratologically, and facilitates a correlation of hitherto unrelated subject areas, within the interdisciplinary framework of literary and media studies, the history of ideas and the sociology of culture. Thus, the diagnostic potential of literature, film and TV series in the perception and processing of disruption will be re-defined. These fictional-narrative art forms are conceptualised as cultural scripts, in which one can discern the fear-laden scenarios of disruption that shape the outlook of Western societies. The project also examines the calculated mise-en-sc?ne of disruption using the example of contemporary art, which because it interrupts routines of perception and communication, especially when an artwork provokes a scandal, questions formulas of societal self-description. By focusing on narrativity and performance, the project generates - via the principle of disruption - a figure of reflection that traverses disciplinary boundaries, enhancing the capability of cultural studies to comprehend processes of social integration.';1291000;1291000;ERC-2012-StG_20111124;/ERC-SG;TECHNISCHE UNIVERSITAET DRESDEN;DE;UNIVERSITAET SIEGEN;DE;/SOC;1;0;0;1;0;0 97088;247579;NANOLICOM;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IRSES;FP7;Nanostructured Lithium Conducting Materials;2011-01-01;2014-12-31;;Solid State Ionics, as an interdisciplinary science, covers chemistry, physics and materials science. The applied perspectives, that include high-energy-density batteries, fuel cells, electrolysis cells, chemical sensors, electrochromic devices and solar cells, and the need for their improvements are an important catalyst for designing new materials. Besides these attractive applications, academic research needs to be reinforced since ion transport in disordered materials is still poorly understood. In particular, the study of nanomaterials opens new questions related to the relationship between structure, processing and physical properties.The aim of this exchange program lies on the investigation of (i) the grain size effect and (ii) the crystallinity on ionic transport of Li-conducting materials based on perovskites, compounds with Nasicon structure and LiPON. Amorphous, nanocrystalline and microcrystalline oxides and oxynitride will be synthesized as powders and films. Processing of these materials and sintering will be performed to obtain thick films and high density pellets. Influence of micro and nanostructure on Li mobility will be investigated. TEM, SEM could offer a wealth of information on nanostructured compounds. Systematic investigations performed on these materials, using different dynamic techniques, able to probe static and dynamic properties at the microscopic level, will be useful, i.e. Nuclear Magnetic Resonance on 6Li and 7Li nuclei (with their different techniques: static NMR, MAS-NMR, 2D NMR, Pulse Field Gradient), quasi-elastic neutron scattering, broadband impedance and dielectric spectroscopy. In particular, the relationship between structure and physical properties will be clarified to lead to a rational design of ionic conductors and to an improvement of the electrochemical devices. A strong network between complementary scientists (Chemists, Physicists, Materials Engineers) from EU and Ukraine would be valuable to perform this programme.;189000;189000;FP7-PEOPLE-2009-IRSES;/MC-IRSES;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FR;"AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS;VILNIAUS UNIVERSITETAS;UNIVERSIDAD CARLOS III DE MADRID";"ES;LT";"/SCI;/EDU;/ITT";1;0;0;1;0;0 99541;263657;PPPHS;ONG;FP7-IDEAS-ERC;ERC-SG-SH2;FP7;Prescriptive Prescriptions: Pharmaceuticals and Healthy Subjectivities;2011-08-01;2016-07-31;;"This research asks how pharmaceuticals prescribe the healthy subject. It examines the cultural meanings and expectations attached to four prescription drugs, and compares the policies and practices around their use in two countries, Sweden and the UK. Empirically, it studies prescription medicines on the outer edges of adulthood: the HPV vaccine; hormone treatments for early puberty; alpha-blockers against Benign Prostrate Hyperplasia; and pharmaceutical developments against Alzheimer s disease. This view from the edges of the mature subject will bring into focus the practices and pleasures, responsibilities and rewards the adult subject position contains (or at least promises), the gendered positionalities it entails and culturally specific expectations articulated by medical prescriptions. The project conceptualizes of pharmaceuticals as flexible technologies, as actors which influence our identities but which also work within and are constrained by institutional policies, social values, medical practices and the material world. The study will open new research horizons on two levels: The groundbreaking methodological approach, with hands-on, collaborative analytical work in PhD courses and analysis workshops between the participants and sites, will ensure an interdisciplinary approach by truly in actual research practice combining approaches from Science Technology and Society, Gender Studies and Posthumanist Studies. In addition, while firmly grounded in concepts of performative subjecthood, identity, the Self and materialities, this project will force a re-reading of the empirical material through ideas from early medical sociology texts, work which viewed health, illness and treatments as embedded in and performed by communities rather than as possessions and responsibilities of the individual patient. This collaborative re-reading will challenge theoretical ideas about the medicalization of the healthy subject and critical pharmaceutical studie";1121760;1121760;ERC-2010-StG_20091209;/ERC-SG;LINKOPINGS UNIVERSITET;SE;LANCASTER UNIVERSITY;UK;/SOC;1;0;0;1;0;0 94363;249375;SOCIAL LIFE;ONG;FP7-IDEAS-ERC;ERC-AG-LS8;FP7;The evolution of social life and division of labour;2010-05-01;2016-04-30;;The hallmark of social insect colonies is reproductive division of labour which is often associated with dramatic morphological and behavioural differences between queens, workers and males. The aim of this proposal is three-fold. First, we will use our recently developed fiducial identification system to investigate the general principles of social organisation and division of labour. The video tracking of workers labelled with markers derived from the augmented reality library ARTag allows us for the first time to distinguish up to 2000 individuals and precisely locate them every 500ms, hence allowing large-scale experiments addressing the question of how the behaviour of individual workers is influenced by the joint effects of environmental factors and social interactions. The second related aim is to investigate how the level of altruism within colonies and the reliability of communication systems are shaped by colony kin structure. Because it is not possible to conduct artificial evolution with social insects we will use a new experimental system consisting of colonies of small mobile robots with simple vision and communication abilities. This system permits to conduct hundreds of generations of experimental evolution in colonies with variable group composition to identify the factors affecting the evolution of altruism and communication. Finally, we will complement these studies with a genetic perspective using a remarkable genetic social polymorphism that we recently discovered in the fire ant Solenopsis invicta. The advent of new ultra high-throughput sequencing techniques will allow us to document the steps involved in the evolution of this genetic social polymorphism and test the suggestion that the chromosome involved in the social polymorphism has the properties of a sex chromosome. This project will be highly interdisciplinary, involving skills in evolutionary biology, the study of animal behaviour, bioinformatics, engineering and molecular biology;2497500;2497500;ERC-2009-AdG;/ERC-AG;UNIVERSITE DE LAUSANNE;CH;;;"/BIO;/LIF";1;0;0;1;0;0 109914;618478;FFL Function;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-CIG;FP7;Computational roles of Feed-Forward Loops in neural circuits;2013-09-01;2017-08-31;;"A major goal of Systems Biology is to understand the design principles underlying Biological Networks. Of particular interest are the computational roles of network motifs - circuits that appear in the network multiple times, significantly more than randomly expected. But why would such circuits evolve over and over again in the network? While extensively studied in transcriptional networks, the emergence of network motifs in neural networks is poorly understood. Here we propose to focus on one of the most abundant motifs - the Feed-Forward Loop (FFL) – and study its functional roles in neural networks. To do this, we will use C. elegans worms as the animal model system. With a compact neural network (302 neurons) and a fully-mapped wiring diagram, C. elegans offers a unique opportunity of studying functional dynamics in neural networks in an unprecedented single neuron resolution and in freely-behaving animals. We will use state-of-the-art optogenetic tools together with cutting-edge microfluidic devices to activate/inhibit and measure activity of individual neurons. This experimental system will be combined with modeling and theoretical approaches to decipher the computational roles of FFLs in neural circuits. Moreover, we will study functional dynamics of various FFLs in freely-behaving animals to decipher how circuitry computation eventually dictates behavioral outputs. Throughout the proposed project, we will use a combination of cutting-edge experimental techniques coupled with extensive computational analyses, modeling and theory. The aims of this interdisciplinary project together with the system-level approaches put it in the front line of research in the Systems Biology field.";100000;100000;FP7-PEOPLE-2013-CIG;/MC-CIG;THE HEBREW UNIVERSITY OF JERUSALEM;IL;;;/LIF;1;0;0;1;0;0 109551;609253;MADMAX;ONG;FP7-NMP;NMP.2013.4.0-4;FP7;Advanced Material Textile for Reinforced Structures for Complex Lightweight Applications;2013-08-01;2016-07-31;http://www.madmaxcluster.org/;"The objective of this project is to regroup a cluster of private and academic laboratories supported by key manufacturers from both aeronautic, automotive and railway sectors in order to investigate the possibility to benchmark specific composites : • from the aeronautics. Depending on the application targeted, the cluster will be able to take advantage of the mutual return on experiment in order to identify the safety requirements for the new materials and detect the most suitable range of composite material. • From automotive process: able to produce the composite parts in order to develop the final structure at acceptable cost, keeping rentability of composite industry. • From Railways process : for the standards and norms, which are harmonized at the European level The scientific focus of the MADMAX project is the joint effort concentrating on those scientific and technical items with interdisciplinary topics: material science, interactive materials, simulation, composites and sensoring for : - Development of high performance functionalized materials to 3D complex preforms - Development of automonous system to monitor the composites structures, incorporation of sensors inside the preforms - Development of standards to qualify the composites and the durability - Development of model for fundamental understanding of the structure/property relationship with advanced simulation tools The ultimate goals is to insure the the development of highly innovative textile processes and high performance flexible materials with significant improvement of mechanical behavior and integrated functions, e.g. structural health monitoring and self-healing for composites structures.";1254664,81;1000000;FP7-NMP-2013-CSA-7;/CSA-CA;UNIVERSITE DE VALENCIENNES ET DU HAINAUT-CAMBRESIS;FR;"SOLIANI EMC SRL;INDUSTRIEVERBAND GARNE GEWEBE TECHNISCHE TEXTILIEN EV;FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.;NEXT TECHNOLOGY TECNOTESSILE SOCIETA NAZIONALE DI RICERCA R L;ECOLE NATIONALE SUPERIEURE ARTS INDUSTRIES TEXTILES;ESI GROUP;TEXCLUBTEC;ECOLE CENTRALE DE NANTES;ASSOCIATION POUR LA RECHERCHE ET LE DEVELOPPEMENT DES METHODES ET PROCESSUS INDUSTRIELS;ASSOCIATION UP-tex;KRINGLAN COMPOSITES AG;MIPNET INDUSTRIES;SCUOLA UNIVERSITARIA PROFESSIONALEDELLA SVIZZERA ITALIANA;RAILENIUM;STRATIFORME INDUSTRIES SAS;TECHNISCHE UNIVERSITAET DRESDEN";"IT;DE;FR;CH";/SCI;1;0;0;1;0;0 109814;330460;NIEDPWIT;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IEF;FP7;New Insights in Eating Disorders Paving the Way for Innovative Treatments;;;;"'My project aims at gathering new evidence to treat a major health concern: Eating disorders, including anorexia and bulimia nervosa and food bingeing leading to obesity. Following up on our parallel results showing an addictive component in these disorders and a dual role for serotonin (5-HT) in feeding, we postulate that the transition from the abusive consumption of food (food bingeing) towards excessive food deprivation (anorexia-like behavior), depends on the constitutive activity of the 5-HT-4 receptors (5-HTR4) and on changes from its inactive (R) towards its active state (R*) within the nucleus accumbens (NAc), a structure of the brain’s reward system. To demonstrate that the constitutive activity of 5-HTR4 in the NAc switches the direction of the addiction to food, I will modify the 5-HTR4 activity state using specific pharmacological treatments (from inverse agonist to overexpression) infused in the NAc of behaving brain-specific 5-HT deficient mice (Tph2-/-). Since my preliminary results show that Tph2-/- display feeding alterations (opposite in Tph2-/- and \/-), my first and second objectives will further characterize in detail their feeding pattern and its correlation with 5-HTR4 density in the NAc, body weight and fat storage. My third and fourth objectives test whether infusion of 5-HTR4 inverse agonist (decreased constitutive activity) and 5-HTR4 overexpression (increased constitutive activity) in the NAc induce respectively food bingeing and food refusal via the molecular cascade: cAMP-CART-FosB-?FosB. My experiments will show that controls of the “accumbal addiction pathway” by R and R* 5-HTR4 states are opposed and control the intake of food. Finally, I will realize a preclinical study and pave the way for the first clinical study using 5-HTR4 drugs to treat eating disorders. The realization of this innovative interdisciplinary project is a step further to cure eating disorders and will increase my professional maturity and European excellence.'";261384,6;261384,6;FP7-PEOPLE-2012-IEF;/MC-IEF;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FR;;;/SCI;1;0;0;1;0;0 98873;268523;CASINO;ONG;FP7-IDEAS-ERC;ERC-AG-LS3;FP7;Carbohydrate signals controlling nodulation;2011-05-01;2016-04-30;;Mechanisms governing interaction between multicellular organisms and microbes are central for understanding pathogenesis, symbiosis and the function of ecosystems. We propose to address these mechanisms by pioneering an interdisciplinary approach for understanding cellular signalling, response processes and organ development. The challenge is to determine factors synchronising three processes, organogenesis, infection thread formation and bacterial infection, running in parallel to build a root nodule hosting symbiotic bacteria. We aim to exploit the unique possibilities for analysing endocytosis of bacteria in model legumes and to develop genomic, genetic and biological chemistry tools to break new ground in our understanding of carbohydrates in plant development and plant-microbe interaction. Surface exposed rhizobial polysaccharides play a crucial but poorly understood role in infection thread formation and rhizobial invasion resulting in endocytosis. We will undertake an integrated functional characterisation of receptor-ligand mechanisms mediating recognition of secreted polysaccharides and subsequent signal amplification. So far progress in this field has been limited by the complex nature of carbohydrate polymers, lack of a suitable experimental model system where both partners in an interaction could be manipulated and lack of corresponding methods for carbohydrate synthesis, analysis and interaction studies. In this context our legume model system and the discovery that the legume Nod-factor receptors recognise bacterial lipochitin-oligosaccharide signals at their LysM domains provides a new opportunity. Combined with advanced bioorganic chemistry and nanobioscience approaches this proposal will engage the above mentioned limitations.;2399127;2399127;ERC-2010-AdG_20100317;/ERC-AG;AARHUS UNIVERSITET;DK;;;"/BIO;/LIF";1;0;0;1;0;0 96974;264663;MULTIFACETED CASR;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-ITN;FP7;The role of the Calcium Sensing Receptor (CaSR) in health and disease, implications for translational medicine;2011-01-01;2014-12-31;;"The identification of the extracellular calcium sensing receptor (CaSR) was a crucial step in understanding nutrient sensing in mammals. In mammalian organisms the CaSR has multiple roles: besides calcium homeostasis, it is involved in protection against osteoporosis, blood vessel calcification, prevention against colorectal cancer, is involved in metastasis of breast and prostate cancer cells to bone. The proposed ITN will perform basic and multidisciplinary investigations into the role of the CaSR and will provide experimental data for computational modelling. It will use holistic approaches of systems biology to gain knowledge on mechanisms of CaSR function. We will use intersectoral expertise in revealing the significance of CaSR signalling in cancer, and cardiovascular disease. The purpose of this ITN is to: • Educate and train Early Stage Researchers to become excellent scientists, enable them to gain a holistic view of their specific research area, prepare them for the challenges of working in a highly competitive environment, be it in Academia or in Industry. • Generate a systems biology model for CaSR-dependent signalling in order to find innovative therapeutic approaches and interventions for the natural and synthetic ligands of the CaSR. • Establish long lasting interdisciplinary and intersectoral cooperation among basic, clinical and applied researchers, working on the CaSR to strengthen the European Research Area. Being in a research environment that examines the role of one single molecule in many different tissues (e.g. kidney, intestine, blood vessels) and pathologies (cancer and vascular calcification), will increase the awareness of the young researchers for a holistic approach in understanding CaSR-related pathophysiology. Continuous comparison of the function of the CaSR in systems studied by their fellow ESRs, will sensitize the young researchers for the complexities of biomedical research and advantages of multidisciplinarity.";2915948;2915948;FP7-PEOPLE-2010-ITN;/MC-ITN;MEDIZINISCHE UNIVERSITAET WIEN;AT;"UNIVERSITE DE PICARDIE JULES VERNE;ASTRAZENECA UK LIMITED;STICHTING VU;UNIVERSITA DEGLI STUDI DI FIRENZE;VERENIGING VOOR CHRISTELIJK HOGER ONDERWIJS WETENSCHAPPELIJK ONDERZOEK EN PATIENTENZORG;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;CARDIFF UNIVERSITY";"FR;UK;NL;IT";"/EDU;/NET";1;0;0;1;0;0 98898;275253;PHILOWEB;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-IEF;FP7;Philosophy of the Web: From Hypertext Representations to Collective Intelligence;2011-08-01;2013-07-31;;'In the wake of its technological success and the structural change the World Wide Web has effected on the world, Web designers and researchers are being forced to confront a range of foundational issues with clear philosophical dimensions. These include old philosophical issues in modern guises – issues concerning knowledge, identity and language – as well as new questions raised by the increasingly complex ways in which the Web is embedded in the larger world, as embodied in the Semantic Web and Internet of Things initiatives. In an world increasingly dominated by information technologies like the World Wide Web, our very nature as individuals is gradually changing as our cognitive and social capacities seem increasingly externalized. However, philosophers has only just begun to connect the information technology like the Web to both a French tradition of systematic philosophy that explores the historical origins of conceptual structures and the rigorously analytic Anglo-American approach that requires all claims to be grounded in logic and empirical evidence. By virtue of this fellowship, we hope to begin a wider project that in an innovative manner that binds both these philosophical traditions to a common empirical object of study: the World Wide Web. What is required is a strictly interdisciplinary approach that seeks to place the emerging work in information science on the Web within a larger framework that includes cognition and embodiment, and likewise have that framework be shaped by the latest scientific and technological development of the Web. This fellowship aims to facilitate and structure this goal by by having the work of renown French philosopher of technology Bernard Stiegler serve as the foundation for an analysis of the Web. The eventual goal of the project will be to produce a book-length foundational manuscript, tentatively entitled The Open World: A Philosophy of the Web. The fellowship will take place under Bernard Stiegler of lRI.';178548;178548;FP7-PEOPLE-2010-IEF;/MC-IEF;INSTITUT DE RECHERCHE ET D'INNOVATION;FR;;;"/EMP;/EDU;/NET";1;0;0;1;0;0 98745;267386;IRQUAT;ONG;FP7-IDEAS-ERC;ERC-AG-PE2;FP7;Information and Randomness in Quantum Theory;2011-05-01;2017-04-30;;"Quantum information science is one of the most dynamic and exciting areas of science today, its significance ranging from the ultimate physical limits of information processing, to fundamental issues of quantum mechanics, to new mathematics and prospects of realising novel, enhanced computation and communication technologies. Drawing on ideas from physics, mathematics and computer science, one of the core programmes of this highly interdisciplinary field is to understand and harness quantum mechanics in terms of information theory. Past steps in this programme include Shor's quantum factoring algorithm, quantum cryptography, and the creation of quantum Shannon and entanglement theory. Dramatic recent developments, while opening up exciting new avenues, at the same time pose major challenges: the proof that quantum capacities can be non-additive showed that the landscape of quantum Shannon theory is actually much richer than previously envisaged; the information theory of generalized non-locality pointed out a completely new take on the foundations of quantum mechanics; and mathematical tools such as the probabilistic method have had a major impact across the board from entanglement theory to quantum Shannon theory and statistical mechanics. In the proposed research I will address key current open questions in quantum Shannon theory, including long-standing coding problems, and a deeper understanding of the pervasive non-additivity of quantum capacities; develop probabilistic tools directly related to quantum information; find new entropy inequalities and entropic uncertainty relations; characterise entanglement and non-local correlations in information theoretic terms; and realise an ambitious programme of founding statistical mechanics on generic quantum dynamics.";1440119;1440119;ERC-2010-AdG_20100224;/ERC-AG;UNIVERSITAT AUTONOMA DE BARCELONA;ES;UNIVERSITY OF BRISTOL;UK;"/PSE;/SCI";1;0;0;1;0;0 109980;332165;TEMBO;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IOF;FP7;Tracking Elephants: Mapping pre-colonial African ivory trade networks using Bioarchaeological techniques;2014-08-20;2017-08-19;;TEMBo will map the flow of ivory from archaeological sites in eastern and southern Africa over the past two millennia by training the researcher in a range of bioarchaeological techniques to identify (ZooMS, FTIR) and source (isotope analysis) archaeological ivory artefacts. This information will significantly improve the understanding of regional interactions between coastal points of export and inland communities supplying the ivory for this trade by reconstructing wider Indian Ocean trade networks between some of the most important pre-colonial African states. TEMBo will thus benefit from an outgoing phase where the researcher is based at the University of Cape Town, South Africa in order to obtain access to the ivory material, as well as be trained by world-leading experts in both archaeological ivory analysis and modern elephant ecology, and benefit from knowledge exchange between the archaeologists working on these sites. Though the project is archaeological, the isotope data will have an impact on modern wildlife conservation by extending the existing database of isotopic signatures characterising elephants from different parks and wildlife sanctuaries across southern Africa. Finally, TEMBo will train the researcher in spatial analyst and mapping database software (ArcGIS) to create an online, open-source database of African ivory, and will work with collaborators of TEMBo from different disciplines (archaeology, ecology, conservation, heritage) in utilising this data in a way that is suitable and useful for education, training, and outreach to the public. Thus, a core part of TEMBo will be to train the researcher in outreach and dissemination of interdisciplinary data in a way that is relevant, timely, and educational for a wide range of audiences in Europe and Africa.;202291,2;202291,2;FP7-PEOPLE-2012-IOF;/MC-IOF;UNIVERSITY OF YORK;UK;;;/LIF;1;0;0;1;0;0 109405;912163;EMBCC;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IIF;FP7;Evolution of mutator bacteria in a community context;2016-02-08;2017-02-07;;"The proposed fellowship is designed to provide to a promising post-doctoral specialization in the microbial evolutionary ecology field by pursuing a period of training in Centre for Ecology and Conservation, College of Life and Environmental Sciences at University of Exeter in the UK. Under the supervision of a world’s leading expert in this field, and with further theoretical training, the Fellow would employ this 2 year period to develop and expand upon her highly commended PhD research into how the evolution of Pseudomonas aeruginosa mutation rates is affected by natural microbial communities. This goal will be carry out by taking two different approaches: i) to study what is the impact of natural competitors in the evolution and adaptation of mutator bacteria in a soil community context by using a direct experimental evolution system; ii) to investigate what is the role of community complexity in the selection of P. aeruginosa mutators in cystic fibrosis (CF) chronic airways infections by exploring the correlation between community diversity and prevalence of P. aeruginosa mutators in artificial and natural CF communities. The project will be interdisciplinary; bridging the gap between microbial ecology and clinical microbiology fields and having broad ecological and medical consequences. In addition, with the inclusion of a return phase, this proposal will foster long-term collaborations between Exeter University, UK and Universidad Nacional de Cordoba, Argentina; favoring the transference of knowledge and enhancing EU scientific excellence in research related to microbiology, evolutionary ecology and infectious diseases in order to extend the current state-of-the-art of mutator bacteria evolutionary dynamics.";15000;15000;FP7-PEOPLE-2012-IIF;/MC-IIFR;UNIVERSIDAD NACIONAL DE CORDOBA;AR;;;/SCI;1;0;0;1;0;0 90199;230570;NEUROLEX;ONG;FP7-IDEAS-ERC;ERC-AG-ID1;FP7;Neurocognitive systems for morpho-lexical analysis: The cross-linguistic foundations for language comprehension;2009-09-01;2015-08-31;;Language comprehension is a fundamentally dynamic process, where incoming speech information interfaces with two markedly different neuro-cognitive processing systems a left lateralised fronto-temporal system that is critical for linguistic processes of morphological and syntactic analysis, and a distributed bi-hemispheric system that supports semantic and pragmatic interpretation. This view of the neurocognitive language system has emerged from interdisciplinary research focusing mainly on English. The research proposed here will take our understanding of these systems to a new level of specificity in terms of the spatio-temporal pattern of different language processing procedures across the brain, while achieving a new level of generality by conducting parallel investigations in three contrasting languages. The first strand (English) will use behavioural and neuro-imaging methods (fMRI, MEG) to analyse the neural networks engaged by different types of morpho-lexical complexity. We will contrast specifically linguistic forms of complexity (derivational and inflectional morphology, argument structure, etc.) with more general sources of complexity reflecting on-line competition between different lexical and phrasal interpretations. Research in English suggests that these engage different processing systems across the two hemispheres. The second strand (Polish) examines the neural dynamics of the same sources of processing complexity in a morphologically much richer language, but sharing with English the same concatenative word-formation mechanisms. The third strand will analyse neural responses to processing complexity in the radically different morpho-lexical context of Arabic, where the fundamental mechanism of word formation is non-concatenative, and where key grammatical morphemes serve multiple linguistic functions. These cross-linguistic neuro-cognitive comparisons will provide important new information about the relationship between language and the brain.;2414558;2414558;ERC-2008-AdG;/ERC-AG;THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;UK;MEDICAL RESEARCH COUNCIL;UK;/SCI;1;0;0;1;0;0 98998;269860;RELIGIOWEST;ONG;FP7-IDEAS-ERC;ERC-AG-SH2;FP7;The (re)construction and formatting of religions in the West through courts, social practices, public discourse and transnational institutions;2011-06-01;2015-10-31;;"RELIGIOWEST is an interdisciplinary endeavour to bring together legal, sociological and political insights in the study of religion in the West. It aims at studying : 1) how different western states (in Europe and North America) are redefining their relationship to religions, under the challenge of increasing religious activism in the public sphere, associated with the spread of new religious movements (evangelicalism, cults) and Islam, 2) how this process mobilizes a complex array of often unrelated actors: courts, administrations, business milieus, but also practicing believers who want to be recognized both as citizens and members of a faith community, public opinion eager to curb what is perceived as “foreign” or “extremist” expressions of religion, politicians navigating between political correctness and populism, and “external” actors, like the US government, the European Court of Human Rights and transnational organizations (the Catholic church, the Muslim Brotherhood), 3) how this process is gradually producing a new and common paradigm of the relationship between states, the public sphere and religion, contributing paradoxically to European integration. We intend to make field-works in 12 countries, both in North-America and Europe, adding Turkey. After studying the specific national legal frameworks dealing with religion in public sphere, we intend to analyse the potential convergences in framing a new common paradigm of the place of religion in the public sphere. The project aims at providing tools for a common European policy implementation on religion.";1895232;1895232;ERC-2010-AdG_20100407;/ERC-AG;EUROPEAN UNIVERSITY INSTITUTE;IT;;;/SOC;1;0;0;1;0;0 109736;618346;SAFER;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-CIG;FP7;Detecting slow deformation signals preceding dynamic failure: A new strategy for the mitigation of natural hazards;2014-03-01;2018-02-28;;"We propose a new strategy based on an interdisciplinary unitary and integrated approach aimed to monitor and detect small signals of impending failures and mitigate natural hazards, by: 1) quantify of critical damage thresholds triggering dynamic failure, throughout the ‘In situ’ identification of characteristic slow deformation signals and accelerating patterns before impending ‘large scale’ failure events; 2) set up of early warning models for forecasting the time of rupture with application to natural hazards; 3) transfer of knowledge between multiscale signs of slow deformation before dynamic failure from the laboratory to field. In detail, we propose to develop innovative strategies for forecasting dynamic ruptures by monitoring an unstable patch of the Gollone landslide on the Italian Western Alps, prone to the development of rock falls and repeated failure episodes, preceded by neat and long lasting episodes of slow deformation. In order to do so, we aim to identify the characteristic signs of impending failure, by installing a “site specific” microseismic monitoring (1-200kHz) system for acoustic emission/microseismic (AE/MS), integrated with a conventional monitoring for seismic detection (1-10Hz) and ground deformation monitoring (strainmeters, geophones and accelerometers). The installation of the monitoring network will be accompanied by a detailed geophysical characterization of the test site in order to establish the best nodes position and internal characteristics of the monitored landslide. Rock physical and mechanical characterization along with rock deformation laboratory experiments during which the evolution of related physical parameters under simulated conditions of stress and fluid content will be studied and theoretical modelling will allow to come up with a full hazard assessment and test new methodologies for a much wider scale of applications within EU.";100000;100000;FP7-PEOPLE-2013-CIG;/MC-CIG;UNIVERSITY OF LEICESTER;UK;;;/LIF;1;0;0;1;0;0 105742;307032;QuFerm2D;ONG;FP7-IDEAS-ERC;ERC-SG-PE2;FP7;Quantum simulation of two-dimensional fermionic systems;2012-11-01;2017-10-31;;"Two-dimensional fermionic systems show remarkable physical properties, not only of interest for fundamental science but also directed towards technological application. Two paradigmatic examples are layered high-Tc superconductors and graphene. However, despite of decades of investigations, their theoretical comprehension is far from being complete. In QuFerm2D, I propose to use atomic Fermi gases to study the physics of two-dimensional strongly correlated fermions. Indeed, ultracold atoms are “ideal” quantum simulators of many-body phenomena thanks to the unprecedented possibility of controlling most of the relevant parameters. I want to set up a new machine that will benefit of the recent advances in ultracold atomic system, such as single-site addressability and the full control of the interparticle interactions. Tailoring arbitrary optical potentials will create the perfect environment for implementing quantum models. I want to characterize both the normal and the superfluid phases of layered fermions. At high temperatures I will measure the equation of state to check the validity of the Fermi liquid description, pointing out also the role of fluctuations. In the superfluid regime, I will study the interlayer tunneling, discriminating the coherent Josephson dynamics from the single-particle hopping, and determining the superfluid energy gap. By adding disorder I want to simulate the physics of granular superconductors, testing the robustness of the order parameter and the onset of metallic phases at higher temperatures. The comprehension of these topics will be the natural background to implement the many-body Fermi-Hubbard Hamiltonians in square and honeycomb lattices that are expected to unveil the microscopic mechanisms of high-Tc superconductors and of graphene in presence of strong interactions. I believe that the successful realization of this project will shed new light on the exciting and interdisciplinary field of strongly correlated fermions.";1243200;1243200;ERC-2012-StG_20111012;/ERC-SG;CONSIGLIO NAZIONALE DELLE RICERCHE;IT;;;"/PSE;/SCI";1;0;0;1;0;0 108189;329519;COPING;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IOF;FP7;Policy implementation in stressful times: Analyzing coping strategies of civil servants;2013-08-01;2015-07-31;;This project focuses on coping strategies civil servants use when they experience stress during implementing governmental policies. Consider an insurance physician who has to reassess a huge number of clients receiving a work disability benefit, in order to check whether they are still entitled to this benefit. Will he cope with this high workload by becoming less thorough, handling reassessments quicker? Or will he cope by talking to his manager, arguing that he should receive more time to preserve high quality reassessments? This real-world example shows that insurance physicians can cope with stress during policy implementation in various ways. Policy implementation scholars note that the phenomenon of coping is very important, as some coping strategies seriously threaten the effectiveness and legitimacy of governmental policies. However, coping during policy implementation lacks systematic study. This project thoroughly analyses coping during policy implementation. It makes extensive use of clinical psychology literature, which has an strong track-record on coping. Hence, it follows a truly interdisciplinary approach, combining policy implementation and clinical psychology literature. It has three aims: 1) to construct a definition and classification of ways of coping during policy implementation, 2) to develop a related measurement instrument to measure ways of coping (using surveys), 3) to identify the main antecedents of ways coping (for instance, what causes a civil servant to engage in rule-breaking as a way of coping?). Literature reviews, interviews and surveys methods will be used extensively. The project is innovative in two ways: theoretically (building among else a classification of coping) and methodologically (using advanced quantitative techniques very novel to the policy implementation field). It will be conducted at the prestigious University of California, Berkeley and at the Erasmus University Rotterdam, a top European research university.;181260,6;181260,6;FP7-PEOPLE-2012-IOF;/MC-IOF;ERASMUS UNIVERSITEIT ROTTERDAM;NL;;;/LIF;1;0;0;1;0;0 106161;310191;CHIPCAT;ONG;FP7-NMP;NMP.2012.1.1-1;FP7;Design of Thin-Film Nanocatalysts for On-Chip Fuel Cell Technology;2012-12-01;2016-11-30;;chipCAT aims at the knowledge-driven development of a novel type of thin-film catalysts for silicon-based “on-chip” micro fuel cells (u-FCs). Combining fundamental surface-science, model catalysis, and first-principles computational studies, a detailed understanding of the surface chemistry on complex nanostructured catalysts will be achieved. This microscopic-level understanding will be used to tailor active sites and their mutual interplay at the nanoscale in order to maximize activity and selectivity and to reduce deactivation and poisoning. Starting from new oxide-based materials with minor demand for noble metals, new material concepts will be explored. Target structures defined by fundamental research will then by transferred to standard FC and u-FC catalysis by using advanced thin-film preparation techniques, such as magnetron sputtering and vacuum deposition. Knowledge-transfer between real and model catalysis will be guaranteed with atomic-level control, using a broad spectrum of surface spectroscopies, in-situ/operando spectroscopies, and microscopies with atomic resolution. Using modern microtechnologies, the novel tailor-made catalyst materials will be integrated into working FC test devices. Prototype devices will be fabricated for performance tests with results fed back to fundamental research. Finally, a process for laboratory-scale production of u-FC batches will be developed. Thus, we will connect surface science, model catalysis, state-of-the-art theory, thin-film-technology, applied heterogeneous catalysis, and microtechnology in an interdisciplinary approach, aiming at the development of a new generation of metal-oxide FC catalysts with improved performance and stability. This project not only will allow to drastically reduce or replace usage of critical materials in the related applications but also will open the pathway to groundbreaking energy storage technologies for mobile devices.;4960655,86;3675906;FP7-NMP-2012-SMALL-6;/CP-FP;UNIVERZITA KARLOVA;CZ;"FRIEDRICH-ALEXANDER-UNIVERSITAET ERLANGEN NUERNBERG;UNIVERSITE DIJON BOURGOGNE;SOLVICORE GMBH & CO KG;THUNDERNIL SRL;CONSIGLIO NAZIONALE DELLE RICERCHE;UNIVERSITAT DE BARCELONA;L.E.T. OPTOMECHANIKA PRAHA SPOL SRO;GREENERITY GMBH";"DE;FR;IT;ES;CZ";/SCI;1;0;0;1;0;0 94842;247450;BIOINCMED;ONG;FP7-IDEAS-ERC;ERC-AG-PE5;FP7;Bioinorganic Chemistry for the Design of New Medicines;2010-07-01;2015-12-31;;Bioinorganic chemistry is a rapidly expanding area of research, but the potential for the therapeutic application of metal complexes is highly underdeveloped. The basic principles required to guide the development of metal-containing therapeutic agents are lacking, despite the unique therapeutic opportunities which they offer. It is the goal of the proposed research to establish basic principles of medicinal coordination chemistry of metals that will allow the rational screening of future metallopharmaceuticals. We propose to utilize the power of inorganic chemistry to provide new knowledge of and new approaches for intervention in biological systems. This will be based on improved understanding of reactions of metal complexes under physiological conditions, on improving the specificity of their interactions, and gaining control over the potential toxicity of synthetic metal complexes. The research programme is highly interdisciplinary involving chemistry, physics, biology and pharmacology, with potential for the discovery of truly novel medicines, especially for the treatment of diseases and conditions which are currently intractable, such as cancer. The challenging and ambitious goals of the present work involve transition metal complexes with novel chemical and biochemical mechanisms of action. They will contain novel features which allow them (i) to be selectively activated by light in cells, or (ii) to be activated by a structural transition, or (ii) exhibit catalytic activity in cells. This ground-breaking research potentially has a very high impact and is based on recent discoveries in the applicant s laboratory. A feature of the programme is the use of state-of-the-art-and-beyond methodology to advance knowledge of medicinal metal coordination chemistry.;1565397;1565397;ERC-2009-AdG;/ERC-AG;THE UNIVERSITY OF WARWICK;UK;"UNIVERSITY OF DUNDEE;ERNST-MORITZ-ARNDT-UNIVERSITÄT GREIFSWALD;BIOFYZIKALNI USTAV AKADEMIE VED CESKE REPUBLIKY";"UK;DE;CZ";"/PSE;/MAT;/IND";1;0;0;1;0;0 97298;267173;DNA MACHINES;ONG;FP7-IDEAS-ERC;ERC-AG-PE5;FP7;Nanomachines based on interlocked DNA architectures;2011-03-01;2016-02-29;;DNA-nanotechnology has created different topologies, including replicable ones, nanomachines, patterns, logic gates, or algorithmic assemblies. Interlocked double-stranded (ds) DNA-architectures like catenanes or rotaxanes, wherein individual components can be set in motion in a controlled manner have not been accessible. These molecules represent long-sought devices for nanorobotics and nanomechanics because they possess a unique mechanical bonding motif, not available to conventional building blocks. The project will apply an unprecedented, simple, and modular interlocking paradigm for double-stranded (ds) circular DNA geometries that we have developed in preliminary studies. This will now be taken several crucial steps forward by generating unconventional DNA-, protein-, aptamer-, and ribozyme hybrid architectures containing interlocked structures wherein the motion of individual components can be controlled in many different ways. We will design, construct, and evaluate switchable autonomous DNA-nanomachines that function as rotational motors, muscles, or switches for powering and manipulating nanoscale components. The DNA machines envisaged in this project will be applied, for example, in synthetic supramolecular self-assembly systems that emulate complex biological machines like motor proteins, nucleic acid polymerases, or ATPases. In addition, they will be developed for multiple purposes in biosensing, logic-gate- and memory circuit assembly, and catalysis. This efficient method for constructing interlocked dsDNA nanostructures opens the exciting possibility of conjoining the area of lifesciences with that of nanomechanical engineering, paving entirely new avenues for nanotechnology. The project is highly interdisciplinary and will open a new field with enormous innovative potential and implications ranging from chemistry to synthetic biology, and from the life sciences to nano-engineering.;2499522;2499522;ERC-2010-AdG_20100224;/ERC-AG;RHEINISCHE FRIEDRICH-WILHELMS-UNIVERSITAT BONN;DE;;;"/PSE;/MAT;/IND";1;0;0;1;0;0 106477;301693;TRACETERRE;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IEF;FP7;Tracing Neanderthal Territories: Landscape Organization and Stone Resource Management in South East France;2013-06-24;2015-10-13;;"The story of the Neanderthals has seen an explosion of interest over the past few decades, both in terms of scientific research and popular appetite for facts and narrative about this extinct human species. The recent revelation that Neanderthals made a significant contribution to modern human genomes has intensified the world’s focus, especially on their similarity to early modern humans. Contemporary research questions converge on the nature of Neanderthal adaptations, and the extent of cognitive parallels between the two species. In particular, were there any differences in how Neanderthals organized their lives on scales as large as entire landscapes? The TRACETERRE project aims to advance these key remaining questions by pursuing research using cutting-edge interdisciplinary methods on the Neanderthal archaeology (c. 60-30 ka BP) of South East France. This diverse region represents a key area where examination of the variability in Neanderthal landscape use and resource management can be characterized through analysis of stone tool (lithic) acquisition/exploitation and technology. These apparently elementary aspects of the archaeological record in fact derive from complex cognitive factors, which can reveal much about differences between Neanderthal and early modern human minds. TRACETERRE will for the first time apply petro-archaeological techniques to open-air sites, to determine the nature of Neanderthal landscape organization by accurately tracing lithics to their sources and integrating these sites into wider settlement systems. The project represents a unique opportunity for transnational collaboration to address key questions on Neanderthal territorial organization. Training in a pioneering new technique will diversify the scientific skills of the researcher, at the same time as producing ground-breaking research. TRACETERRE will therefore significantly enhance her prospects for career independence, while contributing to European research excellence.";201932,4;201932,4;FP7-PEOPLE-2011-IEF;/MC-IEF;UNIVERSITE DE BORDEAUX;FR;;;/SCI;1;0;0;1;0;0 98197;269868;SPIKES;ONG;FP7-IDEAS-ERC;ERC-AG-SH3;FP7;Spatial spikes: bridging geography and economics to study distance, agglomeration, and policy;2011-03-01;2016-02-29;;"Economic geographers and geographical economists have been using different methods in order to analyse the location of economic activity. These different approaches to the same topic have, paradoxically, resulted in very similar geographical configurations: a ‘spiky’ world dominated by large metropoli, where intermediate and peripheral locations tend to matter less and less. This apparent similarity in outcomes hides, however, different explanations and policy recommendations. On the explanation side, economists have focused on understanding how the interaction of economic agents in reduced geographical spaces gives rise to large urban agglomerations. Geographers, in contrast, have increasingly concentrated on relative conceptions of space which highlight the importance of the interaction among often far-away places. On the policy side, economists have favoured spatially-blind policies, while geographers are strong advocates of place-based policies. This interdisciplinary proposal will aim at bridging the gap between these two contrasting approaches, by combining concepts and methods developed by economic geographers and geographical economists in order to better understand how economic agglomeration emerges and how the interaction among distant agglomerations contributes to reinforce, rather than weaken, their importance. It will also elaborate on the adequate policy-mix which could be applied in order to optimize policy intervention in diverse geographical context and time settings. In addition to bridging approaches, the proposal will advance knowledge at the frontier of both disciplines with a combination of theoretical and empirical papers revolving around three key sets of questions where new research is particularly needed: 1. Origins and microeconomic dynamics of spatial spikes 2. Territorial dynamics and interactions among and beyond spatial spikes 3. Spatial policy design";1918104,41;1918104,41;ERC-2010-AdG_20100407;/ERC-AG;LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE;UK;"INSTITUTO MADRILENO DE ESTUDIOS AVANZADOS FUNDACION;FUNDACION CENTRO DE ESTUDIOS MONETARIOS Y FINANCIEROS";ES;"/REG;/ENV;/SOC";1;0;0;1;0;0 89753;229830;IC-UP2;ONG;FP7-REGPOT;REGPOT-2008-1-01;FP7;Developing the research potential of Institute of Chemistry at Tallinn University of Technology, Estonia;2009-02-01;2012-01-31;;"The objective of the current proposal is to develop the research potential of Institute of Chemistry at Tallinn University of Technology, Estonia. To achive the general objectives of the proposal, the following activities are foreseen: - stengthening partnerships and establishing new networks with the leading competence centres on the edge of bio-, materials and ICT sciences in Europe; - mobilizing human resources to reinforce competence base in interdisciplinary biochemical and material research; - drawing industry´s and other public attention and recognition to a researcher´s role and contribution to the society through an international conference; - upgrading of research infrastructure; - initation of pan-European joint research projects.";937040;835744;FP7-REGPOT-2008-1;/CSA-SA;TALLINNA TEHNIKAULIKOOL;EE;;;/SCI;1;0;0;1;0;0 104583;322285;LINC-ups;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-CIG;FP7;Local Inclusion in Networked Communities - utilising public spaces;2013-07-01;2017-06-30;;The main aim of the research Vis to gain knowledge about the links between online social networks and offline public spaces using interdisciplinary empirical methods. The LINC-ups Project will address critical issues within the fields of architecture, urban design, sociology and ubiquitous computing as to how merge the currently disparate worlds of online social networks and offline public spaces to in order to reinforce and strengthen social inclusion at a local neighbourhood level. The LINC-ups project will run over four stages and will be set in the South West regional context of a pioneering roll-out of superfast broadband infrastructure. The first stage will identify a pattern of social connections at neighbourhood places, through analysis of qualitative data from diary studies and interviews with residents in five neighbourhoods. This will establish how people understand and act upon their interactions with technology in their everyday life not just in a purely spatial sense, but more importantly how they are situated within their social networks. The second stage will be an observational study of digital interactions in key public spaces located within the five neighbourhoods which will make it will be possible to understand how public spaces within a neighbourhood are affected. The final empirical stage will draw on results from the first two studies to develop a design-based intervention to directly impact upon the possibility for connecting mediated networks and public spaces. The project will deliver both a theoretical framework and in-depth empirical results on how interaction in social networks enabled by technological infrastructures such as high speed broadband affect social inclusion and overcome digital divides. It will also result in a model for creating high quality public spaces that enable trasnfer between local ties and digital social networks that will impact on planning and policy for regional ICT access and neighbourhood renewal.;100000;100000;FP7-PEOPLE-2012-CIG;/MC-CIG;UNIVERSITY OF PLYMOUTH;UK;;;/LIF;1;0;0;1;0;0 107418;331163;EMBCC;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IIF;FP7;Evolution of mutator bacteria in a community context;2013-07-01;2015-06-30;;"The proposed fellowship is designed to provide to a promising post-doctoral specialization in the microbial evolutionary ecology field by pursuing a period of training in Centre for Ecology and Conservation, College of Life and Environmental Sciences at University of Exeter in the UK. Under the supervision of a world’s leading expert in this field, and with further theoretical training, the Fellow would employ this 2 year period to develop and expand upon her highly commended PhD research into how the evolution of Pseudomonas aeruginosa mutation rates is affected by natural microbial communities. This goal will be carry out by taking two different approaches: i) to study what is the impact of natural competitors in the evolution and adaptation of mutator bacteria in a soil community context by using a direct experimental evolution system; ii) to investigate what is the role of community complexity in the selection of P. aeruginosa mutators in cystic fibrosis (CF) chronic airways infections by exploring the correlation between community diversity and prevalence of P. aeruginosa mutators in artificial and natural CF communities. The project will be interdisciplinary; bridging the gap between microbial ecology and clinical microbiology fields and having broad ecological and medical consequences. In addition, with the inclusion of a return phase, this proposal will foster long-term collaborations between Exeter University, UK and Universidad Nacional de Cordoba, Argentina; favoring the transference of knowledge and enhancing EU scientific excellence in research related to microbiology, evolutionary ecology and infectious diseases in order to extend the current state-of-the-art of mutator bacteria evolutionary dynamics.";221606,4;221606,4;FP7-PEOPLE-2012-IIF;/MC-IIF;THE UNIVERSITY OF EXETER;UK;;;/SCI;1;0;0;1;0;0 104184;295843;OVERHEATING;ONG;FP7-IDEAS-ERC;ERC-AG-SH3;FP7;"The three crises of globalisation: An anthropological history of the early 21st century";2012-07-01;2017-12-31;;"The research literature on various dimensions of globalisation is enormous, yet this project constitutes the first major attempt to weave disparate empirical strands together within a shared conceptual framework, namely that of crises resulting from the acceleration and intensification of global processes. Three major crises of globalisation are to be explored and analysed. In the realm of environmental issues/climate change, the quest for transnational legal arrangements ensuring sustainability is counteracted by continued growth in the factors leading to environmental crises. In the financial and economic realm, the vulnerability of the global system became apparent during the recent financial crisis, which continues to send ripples through economies worldwide. In the area of culture contact and cultural sustainability, tensions and frictions with strong elements of identity politics intensify owing to increased interaction and resource competition, at the same time as calls for cosmopolitan values and universalisation of human rights constitute attempts to overcome conflicts. A key term is sustainability in the sense of reproductive capability, and the main research question is to what extent contemporary world society is sustainable in relation to the three crises and their internal dialectics. The project will entail in-depth ethnographic studies, global surveys (drawing chiefly on extant research literature) and comparison. It will result in two Ph D dissertations, academic articles (written by postdoctoral fellows) and a major monograph, as well as an edited volume, academic articles and a book for a general audience, all written by the PI. This interdisciplinary and comparative project, based mainly on anthropological approaches, aims to build theory and analyse empirical processes shedding light on, and creating a fuller understanding of, the transitions characterising the present world. The intellectual and societal relevance is potentially huge.";2496344;2496344;ERC-2011-ADG_20110406;/ERC-AG;UNIVERSITETET I OSLO;NO;;;"/REG;/ENV;/SOC";1;0;0;1;0;0 95361;254575;CYANOBAC-RESPIRATION;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IEF;FP7;Organization and Dynamics of Respiratory Electron Transport Complexes in Cyanobacteria;2010-08-01;2012-07-31;;Photosynthesis and respiration are two of the most important biological processes on Earth for energy supply. Cyanobacteria can perform both oxygenic photosynthesis and aerobic respiration in thylakoid membrane. However, compared to extensively studied photosynthesis, knowledge of respiration is not satisfactory. So far, the long-range organization and mobility of respiratory complexes have never been investigated, and how photosynthesis and respiration are regulated in vivo is unknown. This project aims to determine the spatial distribution and mobility of respiratory systems in cyanobacteria, and to elucidate the interaction and regulation of respiratory and photosynthetic electron transport chains in thylakoid membrane. The first aim is to construct cyanobacterial strains containing respiratory complexes tagged with GFP and mCherry. Then high-resolution fluorescence confocal microscopy and fluorescence recovery after photobleaching allow to study the distribution and mobility of fluorescently tagged respiratory complexes and naturally florescent photosynthetic proteins. To supplement the fluorescence observations, using electron microscopy and scanning probe microscopy, this project will further examine the supramolecular organization of photosynthetic and respiratory complexes in thylakoid membrane at the molecular level. Based on the in vivo and in vitro findings, it is possible to draw a picture of the large-scale distribution of respiratory and photosynthetic complexes in vivo at the level of individual complexes, and to explore the coordination and regulation between photosynthesis and respiration. Advanced understanding of the bioenergetic pathways will practically benefit biofuel and biodiesel engineering, to exploit and improve renewable energy production by controlling the complex pathways of electron transport in photosynthetic organisms. The interest of the interdisciplinary project covers molecular biology, biochemistry, biophysics and nanotechnology.;179603,2;179603,2;FP7-PEOPLE-2009-IEF;/MC-IEF;QUEEN MARY UNIVERSITY OF LONDON;UK;;;"/SCI;/EDU;/ITT";1;0;0;1;0;0 108349;600385;ITHACA;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-COFUND;FP7;ITHACA;2013-06-01;2017-12-31;;"'The Beatriu de Pinós programme (BP) has been running successfully since 2005 and aims to promote postdoctoral research and transnational mobility in all fields of research in Catalonia. The grant will be two years long and will enable outstanding junior researchers from all nationalities to train and conduct research in any Catalan excellence research group on a project of their choice. The main objectives of the BP ITHACA project are: a) to improve the quality of postdoctoral research training; b) to enable outstanding junior researchers to develop their research careers at an advanced and more independent level in a leading research group or institution in Catalonia; c) and increase the competitiveness of the Catalan scientific community and for extension the European one. The long term objective of BP-Ithaca is to significantly contribute to the career development of more researchers and qualified future independent research leaders. The Cofund contribution will be used to increase the number of fellowships and provide better career opportunities and favourable working conditions in accordance with the European Charter of Researchers. Besides high level interdisciplinary scientific research training, junior researchers will receive additional vocational training in complementary skills and a special personalize career development support will also be given during and after the grant finishes. Catalonia has fostered a successful research and knowledge hub in the south of Europe in a relatively short time and provides the postdoctoral researcher the best environment to deepen scientific skills and develop new ones. The programme is driven by AGAUR (Agency for Management of Universities and Research grants), the Catalan Government Agency responsible for awarding grants for universities and research as well as promoting research and science.'";11570353,2;4628141,28;FP7-PEOPLE-2012-COFUND;/MC-COFUND;AGENCIA DE GESTIO D'AJUTS UNIVERSITARIS I DE RECERCA;ES;;;/LIF;1;0;0;1;0;0 107408;328257;ZOT;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IEF;FP7;Zoroastrian Text(ile)s: Regulations, Symbolism, Identity;2013-07-01;2015-06-30;;The project “Zoroastrian Text(ile)s: Regulations, Symbolism, Identity” offers an innovative interdisciplinary approach to the understanding of the modalities and changes in the use of textiles in the Zoroastrian communities of the Iranian milieu (from ca. the 2nd millennium BCE through to the 17th century CE).;221154,6;221154,6;FP7-PEOPLE-2012-IEF;/MC-IEF;KOBENHAVNS UNIVERSITET;DK;;;/SCI;1;0;0;1;0;0 93233;245928;TRANSMED;ONG;FP7-REGPOT;REGPOT-2009-1;FP7;Translating basic research findings in major human diseases;2010-01-01;2013-06-30;;Improvement of human health requires translation of the basic research discoveries into practical applications for human disease, including biomarker identification, novel clinical tools, and medications. The scope of TranSMed is to support the development of a center of excellence in the EU target area of “translational research for major human diseases”, in the convergence region of Attica, Greece. The applicants will combine their expertise for the development of a facility for improvement of human health in the mission areas of obesity, metabolic syndrome and neurodegeneration. The principal aim of the group is to maintain and advance academic excellence, to enhance innovative research , and ultimately advance diagnosis and management of the above diseases. Participants have made substantial scientific contributions, and now are poised as a group to get to the next level and make a major impact on translational research. This will be achieved by unlocking their potential via the actions supported by REGPOT1, such as (i) upgrading the research capability by hiring experienced scientists and expansion of the equipment infrastructure (ii) integration in the ERA via strategic partnerships, including twinning, for transfer of knowledge from excellent EU centers, (iii) development of new lines of research including bidirectional communication with clinicians, and training in interdisciplinary approaches (iv) development of a platform for data mining and bioinformatics approaches. The above will be supported by networking activities, such as international workshops, to promote research collaborations with industrial partners. The latter will increase the visibility of the group and of the regional community. Ultimately, TranSMed can provide the basis for related projects to be supported through the cohesion policy program, resulting in dissemination of similar actions at national level and in the wider EU area including the new member countries in the Balkan vicinity.;1664960;1479316;FP7-REGPOT-2009-1;/CSA-SA;IDRYMA IATROVIOLOGIKON EREUNON AKADEMIAS ATHINON;EL;;;"/REG;/LEG";1;0;0;1;0;0 94019;229715;IARC FELLOWS;ONG;FP7-PEOPLE;PEOPLE-2007-2-3.COFUND;FP7;IARC International Fellowships Programme;2010-03-01;2014-11-30;;The IARC Fellowship Programme aims to promote international collaboration in those aspects of cancer research related to IARC's own programme by providing training at the Agency in Lyons, France, for postdoctoral scientists from low- to medium-resource countries who wish to pursue a career in cancer research. Fellowships are awarded in the following areas of cancer research: epidemiology, biostatistics, environmental chemical carcinogenesis, cancer etiology and prevention, infection and cancer, molecular cell biology, molecular genetics, molecular pathology and mechanisms of carcinogenesis, with emphasis on interdisciplinary projects. Postdoctoral Fellows are selected from applicants from any country other than those classified as high-income economies by the World Bank. Candidates must have spent less than five years abroad (including doctoral studies) and have finished their doctoral degree within five years of the closing date for application or be in the final phase of completing their doctoral degree (M.D. or Ph.D.). They must provide evidence of their ability to return to their home country and keep working in cancer research. Applicants are expected to contact the Group(s) of their choice at IARC before application in order to interact closely to establish a proposed programme of mutual interest. These fellowships are for a period of 2 years, the extension for a second year being subject to satisfactory appraisal. Upon successful completion, a modest return grant may be awarded to help the candidate start up an independent research programme linked to IARC activities upon return to his/her home country. The selection of postdoctoral Fellows is made by a Selection Committee composed of scientists of international reputation in the field of cancer research who are not members of the IARC staff, together with scientists working in the IARC.;2098800;839520;FP7-PEOPLE-2007-2-3-COFUND;/MC-COFUND;CENTRE INTERNATIONAL DE RECHERCHE SUR LE CANCER;FR;;;"/REG;/SCI";1;0;0;1;0;0 99539;263271;ZAPÁS;ONG;FP7-SPACE;SPA.2010.3.2-01;FP7;Assessment and Monitoring of Forest Resources in the Framework of the EU-Russia Space Dialogue;2011-08-01;2014-07-31;http://zapas.uni-jena.de;"ZAPÁS delivers a set of procedures and products for forest resource assessment and monitoring. The team consists of a balanced contribution of leading experts from Europe and Russia in the field of Earth observation for forestry and includes a Russian Forest Research Institute which also apply remote sensing techniques. ZAPÁS investigates and cross validates methodologies using both Russian and European Earth observation data to develop a worldwide observation system. Earth observation data include ENVISAT MERIS and ASAR in different acquisition modes, METEOR-M and RESURS-DK1. The methodologies include state-of-the-art optical and radar retrieval algorithms and their improvement as well as investigation of innovative synergistic approaches. Products include biomass maps and biomass change for the years 2007-2008-2009 on a local scale, a biomass and improved land cover map on the regional scale, and in addition, a 1 km scale land cover map as input to a carbon accounting model. These products serve the inventory community (e.g. FAO Forest Ressource Assessment) as well as the Kyoto Protocol implementation bodies. ZAPÁS is unique with respect to the team composition, Earth observation operational expertise, interdisciplinarity and envisioned improved synergistic products. In specified regions land cover change dynamics, specifically land abandonment, will be investigated. A ZAPÁS unique feature is the investigation of up- and down-scaling effects of data and products to improve the overall accuracies. A bi-lingual webportal (as already existing at partner locations) provides access to findings, data and products to the outside forest and Earth observation community.";668736,25;499990;FP7-SPACE-2010-1;/CP-FP-SICA;Friedrich Schiller University Jena;DE;"""Joint Stock Company """"Russian Space Systems"""""";V.N.SUKACHEV INSTITUTE OF FOREST SIBERIAN BRANCH OF THE RUSSIAN ACADEMY OF SCIENCES;INTERNATIONALES INSTITUT FUER ANGEWANDTE SYSTEMANALYSE;SPACE RESEARCH INSTITUTE OF RUSSIAN ACADEMY OF SCIENCES";"RU;AT";"/COO;/SPA";1;0;0;1;0;0 98740;276155;BioNanopore;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-IIF;FP7;Biomimetic nanopore for a mechanistic study of the nuclear pore complex;2011-06-01;2013-05-31;;Compartmentalization of the eukaryotic genome into a nucleus necessitates nuclear import and export to achieve basic cellular processes. The nuclear pore complex (NPC) is a large (60 - 125 MDa) macromolecular structure in eukaryotic cells, where it spans the nuclear membrane and serves as the gatekeeper of nucleocytoplasmic transport. While water, ions, and small molecules can freely diffuse through the NPC, macromolecules larger than 25 - 40 kDa cannot pass the NPC’s permeability barrier unless ferried by specific transport proteins called nuclear transport receptors (NTRs). While the structural arrangement and biochemistry of the complex have been largely worked out, the underlying mechanism of the pore’s transport and selectivity remains poorly understood. Mechanistic studies of the NPC have been largely carried out in vivo because in vitro reconstitution of the complex is not possible. Here, I propose to develop a biomimetic NPC-like system based on solid-state nanopore technology to conduct a real-time, single-molecule investigation into the mechanism of NPC transport and selectivity. Both electrical detection and a novel optical-electrical method will be used to monitor the translocation of individual substrates through a single biomimetic pore. The biomimetic approach proposed here will provide a significant step forward in experimentally studying the NPC, by affording an in vitro system that will allow for rigorous testing of key NPC proteins and their mechanistic role in transport and selectivity. This work will be carried out in the laboratory of Professor Cees Dekker, who is a world leader in nanofabrication and the application of solid-state nanopores to biology. My expertise in single-molecule biophysics, fluorescence microscopy, and biochemistry is well suited to complement the resources of the Dekker lab to collectively meet the interdisciplinary demands of this innovative effort.;185540,8;185540,8;FP7-PEOPLE-2010-IIF;/MC-IIF;TECHNISCHE UNIVERSITEIT DELFT;NL;;;"/SOC;/COO";1;0;0;1;0;0 90981;227265;FUNCITREE;ONG;FP7-KBBE;KBBE-2008-1-2-05;FP7;Functional Diversity: An ecological framework for sustainable and adaptable agro-forestry systems in landscapes of semi-arid and arid eco-regions;2009-05-01;2013-06-30;;The increasing demand of livestock products, larger climate uncertainty and resource degradation, and the rampant poverty of farmers in the semi-arid tropics calls for modernized agroforestry systems (AFS) capable of providing multiple functions. The project will develop regionally specific, trait-based and field tested AFS capable of providing critical agro-ecosystem functions in semi-arid Africa and Central America. The primary objective is to provide farmers with a portfolio of regionally suitable tree and shrub species organized by their traits or attributes, in relation to the provisioning of multiple services, as perceived by the farmers and in terms of fundamental ecological functions. The project will make substantial contributions to AF and ecological science through its integration of theories and concepts from both fields, and will thereby provide a scientifically based model for the design of modernized AFS. The project will identify, and characterize the main factors influencing the adoption/non adoption of AF in selected target areas. It will improve the performance of AFS in dry and marginal areas with particular focus on how species can be assembled according to their traits to improve the multi-functionality of AFS and will identify the potential of new multipurpose tree species suitable for AF in dry and marginal areas by grouping these species according to their functional traits and their capacity to provide critical AFS services. The project will specifically enhance the synergies between the species traits and model how trait combinations contribute to the multi-functionality of AFS including soil, trees, crop/pasture and livestock. We will evaluate the short and medium environmental impacts of AF and its socio-economic implications through sophisticated interdisciplinary models and will produce policy recommendations aimed at promoting AFS and related husbandry practices best adapted to specific local needs, yet universal in scope.;3811001;2903597;FP7-KBBE-2008-2B;/CP-SICA;STIFTELSEN NORSK INSTITUTT FOR NATURFORSKNING NINA;NO;"CENTRO AGRONOMICO TROPICAL DE INVESTIGACION Y ENSENANZA CATIE;INSTITUT SENEGALAIS DE RECHERCHES AGRICOLES;INSTITUT D'ECONOMIE RURALE;AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS;CENTRE DE COOPERATION INTERNATIONALE EN RECHERCHE AGRONOMIQUE POUR LEDEVELOPPEMENT - C.I.R.A.D. EPIC;WAGENINGEN UNIVERSITY";"CR;SN;ML;ES;FR;NL";"/AGR;/SDT";1;0;0;1;0;0 100154;273759;ColliAM;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-IEF;FP7;Possible Stimulation by Mycophagous Collimonas Bacteria of Arbuscular Mycorrhizal Functioning;2011-05-01;2013-04-30;;Arbuscular mycorrhiza (AM) fungi are key components in sustainable agriculture as they enable efficient nutrient uptake by crops when chemical fertilization is reduced. AM fungal functioning is, however, influenced by other microbes that interact with their hyphae. One of these microorganisms is the recently discovered genus Collimonas. Collimonas bacteria show a great potential application in sustainable agriculture both as a biocontrol agent and as a P-solubilizer, based on its mycophagy (feed on fungi) and mineral weathering abilities. Here, I propose for the first time, the possible application of AM fungi and Collimonas bacteria as a consortium of beneficial microorganisms for sustainable agriculture purposes. The successful application is dependent on our understanding of the interaction between Collimonas and AM fungi. The aim of this proposal is to gain insights on the mechanisms involved in the interaction, its relevance in natural ecosystems and its influence on plant performance. The Collimonas-AM fungal interaction has both positive (increased hyphal branching, higher supply of nutrients) and negative (consumption of AM hyphae) components. My general hypothesis is that the interaction between both microorganisms commonly occurs in nature and results in a positive mutualistic relationship from which plants benefit. The hyphosphere would provide a beneficial environment for Collimonas growth, which in turn would increase nutrient availability for AM fungi and, consequently, for the plant. To test my hypothesis I propose a highly interdisciplinary approach combining advanced molecular, biochemical and microscopic techniques in natural ecosystems, microcosms and in vitro experiments. The results are expected to bring out new leads for novel strategies in sustainable agriculture by improving AM fungi functioning through Collimonas inoculation. The main benefits of the program for my career are enhanced independency and experience in cutting-edge techniques.;237499,8;237499,8;FP7-PEOPLE-2010-IEF;/MC-IEF;KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW;NL;;;"/EMP;/EDU;/NET";1;0;0;1;0;0 109166;331605;GTOXOME;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IEF;FP7;The impact of genotoxic stress on the mRNA-interactome and RNA-regulons;2014-01-01;2015-12-31;;RNA-binding proteins (RBP) play critical roles in stress responses like DNA-damage through interactions with elements in functionally related RNAs, termed regulons. One of the most cytotoxic forms of DNA-damage are DNA double strand breaks (DSB), that can lead to mutagenic events and when improperly repaired to cell death. This proposed project focuses on the dynamics of the global RBP network (mRNA-interactome) and RNA-regulons of mouse fibroblasts (NIH-3T3) cells in response to genotoxic stress. The “RNA-regulon” model implies that RBPs control functionally related mRNAs via cis-regulatory elements in these RNAs. Using mRNA-interactome capture and high-resolution quantitative proteomics, I will comprehensively identify mRNA-binding proteins involved in immediate DNA-repair and cell death responses to genotoxic stress. By employing deep sequencing and crosslink immunoprecipitation approaches, I will highlight the controlled RNA-networks and their influence on cell survival. Taken together, this project aims to address key questions of the role for RBPs in the DNA-damage response at different stages and the identification of their RNA-regulons. Furthermore, it opens new perspectives in posttranscriptional regulation after the cells exposure to genotoxic stress. The innovative nature of this interdisciplinary project involves European collaborators, which creates excellent inter-European-networking. The development of a novel research area will showcase the cutting-edge research performed in the ERA thus directly contribute to the European Work Programme by enhancing the attractiveness of Europe for third country and European top-scientists.;161968,8;161968,8;FP7-PEOPLE-2012-IEF;/MC-IEF;EUROPEAN MOLECULAR BIOLOGY LABORATORY;DE;;;/SCI;1;0;0;1;0;0 108747;316210;BEYOND;ONG;FP7-REGPOT;REGPOT-2012-2013-1;FP7;Building Capacity for a Centre of Excellence for EO-based monitoring of Natural Disasters;2013-06-01;2016-05-31;;BEYOND relies on existing state-of-the-art and interdisciplinary collaboration with twining organizations highly esteemed in the European Research Area, for Building Capacity for a Centre of Excellence dedicated to Natural Disaster Management in southeastern Europe, including European Balkan countries, with a potential to expand to an even wider geographic area through harmonizing the observational capabilities available in the partners. BEYOND a) sets up integrated observational solutions allowing different monitoring networks (space borne and in-situ) to cooperate in a complementary, unified and coordinated manner, b) create archives and data bases of long series of observations and higher level products, and c) make the observations and products available for exploitation with state-of-the-art science and models, hence providing the involved stakeholders, scientists and/or institutional users, with substantial information for down streaming to local needs for handling natural and human induced disasters. To accomplish this goals BEYOND is structured around 6 Work Packages namely, WP1 “Project Management”, WP2 “Personnel Recruitment”, WP3 “Infrastructure and capacity building”, WP4 “Dissemination”, WP5 “Exchange of know-how and experience”, and WP6 “Exploitation and Intellectual Property development”. It is a 36 month project building upon, a) the collaboration with high-level scientific organizations from Germany, Italy, Spain, UK, Norway, Serbia, Swiss, and Turkey, and b) the support and participation of ESA, and WMO international organisations. BEYOND envisages for the recruitment of new researchers, and establishes a detailed exploitation and targeted dissemination plan through workshops, publications, web portal, etc. BEYOND covers all the priorities defined by the work program, substantially contributing to human, institutional and infrastructure capacity building.;2886732;2305650;FP7-REGPOT-2012-2013-1;/CSA-SA;NATIONAL OBSERVATORY OF ATHENS;EL;;;/SCI;1;0;0;1;0;0 192220;335536;CREAM;ONG;FP7-IDEAS-ERC;ERC-SG-SH4;FP7;Cracking the emotional code of music;2014-10-01;2019-09-30;;"'This project aims to 'crack' the emotional code of music, i.e. to provide, for the first time, a precise characterization of what type of music signal is able to activate one emotion or another. Research into this problem so far has been mainly correlating indistinct emotional reactions to uncontrolled musical stimuli, with much technical sophistication but to little avail. Project CREAM builds on the PI's unique bi-disciplinary career spanning both computer science and cognitive neuroscience, to propose a radically novel approach: instead of using audio signal processing to simply observe musical stimuli a posteriori, we will harvest a series of recent developments in the field to build powerful new tools of experimental control, able to engineer musical stimuli that can activate specific emotional pathways (e.g. music manipulated to sound like expressive speech, or to sound like survival-relevant environmental sounds). By combining this creative use of new technologies with a well-concerted mix of methods from experimental psychology and cognitive neuroscience (incl. psychoacoustics, fNIRS brain imaging, EEG/ERP paradigms, intercultural studies, infant studies), project CREAM will yield the first functional description of the neural and cognitive processes involved in the induction of emotions by music, and establish new avenues for interdisciplinary research between the life sciences and the information sciences. But most spectacularly, the fundamental breakthroughs brought by project CREAM will unlatch the therapeutic potential of musical emotions. Music will become a cognitive technology, with algorithms able to 'engineer' it to mobilize one neuronal pathway or another, non-intrusively and non-pharmacologically. Within the proposed 5-year plan, support from the ERC will allow to implement a series of high-impact clinical studies with are direct applications of our findings, e.g. for the linguistic rehabilitation of aphasic stroke victims.'";1499992;1499992;ERC-2013-StG;/ERC-SG;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FR;;;/SOC;1;0;0;1;0;0 90710;221519;NCAF;ONG;FP7-PEOPLE;PEOPLE-2007-4-3.IRG;FP7;Noncommutative Geometry of Algebra Factorisations;2009-01-01;2010-08-31;;This is an interdisciplinary proposal that explores a rich new vein of interaction between algebra in the form of `noncommutative geometry' and deep applications in mathematical physics including elementary particle physics and quantum gravity. These are all areas of existing excellence in the EU and the innovative proposal will help to maintain the EU competiveness and high profile in these areas and to promote new synergies by their interaction. Specifically, it is proposed to develop a general theory of factorisation of noncommutative geometrical structures or conversely of building up such structures from the same data on each factor of an algebra factorisation, and to apply this new mechanism for construction of noncommutative geometries to quantum groups, quantum spacetimes (which includes astrophysical implications related to the ESA/NASA GLAST initiative) and other applications as indicated. The project will consolidate the novel pure mathematical work in the Researcher's recent PhD thesis and related papers and add to this new extensive training on the quantum groups and mathematical physics sides, thereby providing an enhanced platform for his long term career development. The training will also enhance collaboration with and transfer knowledge back to the researchers `home base' in Granada or to wherever the Researcher finally settles (which is expected to be in Spain in the long term). The training will also include organising workshops, speaking at high level national and international conferences and high-level scientific writing.;161792,99;161792,99;FP7-PEOPLE-2007-2-1-IEF;/MC-IEF;QUEEN MARY UNIVERSITY OF LONDON;UK;;;"/SCI;/COO";1;0;0;1;0;0 94667;251420;REPLIXCEL;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IAPP;FP7;Highly efficient new generation synthetic RNA-replicon based vaccine;2010-04-01;2014-03-31;;"The project seeks to create a novel, efficacious vaccine against influenza virus; a new type of synthetic vaccine readily adaptable to meet whichever influenza virus subtype may arise. A new generation of RNA-replicon technology will be employed combined with nanoparticles and innovative adjuvants for targeting of dendritic cells and efficient antigen expression. The consortium comprises two SMEs and two academic institutions each having unique and patented expertise such as replicon technology, nanoparticle technology, adjuvant chemistry, and surface modification chemistry to attach targeting moieties. As a highly interdisciplinary project, extensive exchange of knowledge between the project partners will be required in particular between product focused SMEs (nanoparticles, adjuvants) and technology excellence of academic institutions (replicon technology, surface modification chemistry).";2591172;2591172;FP7-PEOPLE-2009-IAPP;/MC-IAPP;THE UNIVERSITY OF MANCHESTER;UK;"EIDGENOESSISCHES DEPARTEMENT FUER WIRTSCHAFT, BILDUNG UND FORSCHUNG;Medipol SA;EMC MICROCOLLECTIONS GMBH";"CH;DE";"/SCI;/EDU;/ITT";1;0;0;1;0;0 90063;227878;COLLMOT;ONG;FP7-IDEAS-ERC;ERC-AG-ID1;FP7;Complex structure and dynamics of collective motion;2009-03-01;2015-02-28;;Collective behaviour is a widespread phenomenon in nature and technology making it a very important subject to study in various contexts. The main goal we intend to achieve in our multidisciplinary research is the identification and documentation of new unifying principles describing the essential aspects of collective motion, being one of the most relevant and spectacular manifestations of collective behaviour. We shall carry out novel type of experiments, design models that are both simple and realistic enough to reproduce the observations and develop concepts for a better interpretation of the complexity of systems consisting of many organisms and such non-living objects as interacting robots. We plan to study systems ranging from cultures of migrating tissue cells through flocks of birds to collectively moving devices. The interrelation of these systems will be considered in order to deepen the understanding of the main patterns of group motion in both living and non-living systems by learning about the similar phenomena in the two domains of nature. Thus, we plan to understand the essential ingredients of flocking of birds by building collectively moving unmanned aerial vehicles while, in turn, high resolution spatiotemporal GPS data of pigeon flocks will be used to make helpful conclusions for the best designs for swarms of robots. In particular, we shall construct and build a set of vehicles that will be capable, for the first time, to exhibit flocking behaviour in the three-dimensional space. The methods we shall adopt will range from approaches used in statistical physics and network theory to various new techniques in cell biology and collective robotics. All this will be based on numerous prior results (both ours and others) published in leading interdisciplinary journals. The planned research will have the potential of leading to ground breaking results with significant implications in various fields of science and technology.;1248000;1248000;ERC-2008-AdG;/ERC-AG;EOTVOS LORAND TUDOMANYEGYETEM;HU;;;/SCI;1;0;0;1;0;0 92719;239898;DYCOCA;ONG;FP7-IDEAS-ERC;ERC-SG-PE5;FP7;DYNAMIC COVALENT CAPTURE: Dynamic Chemistry for Biomolecular Recognition and Catalysis;2009-10-01;2014-09-30;;Molecular recognition plays a fundamental role in nearly all chemical and biological processes. The objective of this research project is to develop new methodology for studying and utilizing the noncovalent recognition between two molecular entities, focussing on biomolecular receptors and catalysts. A dynamic covalent capture strategy is proposed, characterized by the following strongholds. The target itself self-selects the best component out of a combinatorial library. The approach has a very high sensitivity, because molecular recognition occurs intramolecularly, and is very flexible, which allows for an easy implementation in very diverse research areas simply by changing the target. The dynamic covalent capture strategy is strongly embedded in the fields of supramolecular chemistry and (physical) organic chemistry. Nonetheless, the different work programmes strongly rely on the input from other areas, such as combinatorial chemistry, bioorganic chemistry, catalysis and computational chemistry, which renders the project highly interdisciplinary. Identified targets are new synthetic catalysts for the selective cleavage of biologically relevant compounds (D-Ala-D-Lac, cocaine and acetylcholine, and in a later stage peptides and DNA/RNA). Applicative work programmes are dedicated to the dynamic imprinting of monolayers on nanoparticles for multivalent recognition and cleavage of biologically relevant targets in vivo and to the development of new screening methodology for measuring chemical equilibria and, specifically, for the discovery of new HIV-1 fusion inhibitors.;1400000;1400000;ERC-2009-StG;/ERC-SG;UNIVERSITA DEGLI STUDI DI PADOVA;IT;;;"/PSE;/IPS;/TEL";1;0;0;1;0;0 108087;326933;ORATOR;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IEF;FP7;Integrating Object Recognition and ActiOn for action sentence production and comprehension in a developmental humanoid Robot;2013-05-15;2015-07-15;;Recent models from cognitive robotics research have recently begun to appreciate the entwined relationship between language and action, and have proposed to ground robots’ language understanding in sensorimotor representations. These models, however, focused mainly on the one-way relation between language and action, neglecting its bi-directional character. Hence, the primary aim of this research is to provide an experimental and computational framework for explaining how the processes of language interact with other processes such as motor control. We intend to tackle this issue from the developmental robotics perspective. This highly interdisciplinary field of robotics benefits greatly from the direct collaboration with child psychologists and the modeling of child development phenomena in robots. One classic approach to studying child development is to look at the errors that children sometimes commit. Young children, for example, sometimes make a serious attempt to perform impossible actions on miniature objects. We suggest that these errors may result from the onsets of language and propose to test it empirically: does a child with a larger vocabulary and/or more advanced grammatical skills perform more errors than a less advanced child? The hypotheses derived from the study will be replicated in experiments with the developmental robotics platform iCub to demonstrate the impact of such an embodied cognitive approach in the design of integrated action and language capabilities in robots. This research will contribute to the knowledge of cross-talk between language and motor structures and suggest a possible developmental mechanism, and endow a robot with the ability to comprehend sentences on object interaction. The fellowship will also provide the researcher with an opportunity to further develop multidisciplinary skills in child psychology and developmental robotics methods, and transferable skills for R&D in academia and service robotics industry.;221606,4;221606,4;FP7-PEOPLE-2012-IEF;/MC-IEF;UNIVERSITY OF PLYMOUTH;UK;;;/SCI;1;0;0;1;0;0 108587;327465;SLAVHERIT;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IOF;FP7;Breaking the Silence: Archaeological Discoveries and the Making of Public Slave Heritage in Rio de Janeiro;2013-06-01;2016-05-31;;SLAVHERIT aims to understand how slave memory, after long institutional oblivion, is being publicly memorialised in Rio de Janeiro. This process of memorialisation is considered to be in line with recent multicultural trends in Brazil, by enhancing the visibility of Afro-descendants in national history. That said, no literature has explored this process critically within the existing context of Brazilian racial politics. In addition, no literature sees how this slave heritage is actually being built, what it represents for different social actors, and which power relations prevail in its establishment. SLAVHERIT addresses these questions in an original way, taking an interdisciplinary approach that combines the fields of history, anthropology and politics. In doing so, the project deals with slavery not as a fact locked in the past but as a process relevant for political uses of memory in the present. While focusing on Brazil, SLAVHERIT will lead to conceptual and methodological contributions that will also be interesting for other contexts. In Europe, in fact, multicultural inclusion is an ongoing and heated issue in policy making, while studies of memory are flourishing and the legacy of Atlantic slavery on persisting social exclusion in European societies is increasingly being considered. Through a range of competencies to be achieved in Brazil, SLAVHERIT will broaden the applicant’s expertise in the study of race relations and slave memory in Latin America, producing skills for his effective reintegration into the United Kingdom as a researcher, academic and consultant in the proposed field. SLAVHERIT will also encourage the circulation of knowledge between Brazil and Europe, contributing to European excellence in Latin American studies, and increasing Brazil’s presence in European research on slave memory across the Atlantic.;273826,2;273826,2;FP7-PEOPLE-2012-IOF;/MC-IOF;KING'S COLLEGE LONDON;UK;;;/LIF;1;0;0;1;0;0 87584;204513;DCBIF;ONG;FP7-IDEAS-ERC;ERC-SG-LS4;FP7;Flight dynamics and control of birds and insects;2008-06-01;2014-05-31;;Insects bristle with sensors, but how do they exploit this rich sensory information to achieve their extraordinary stability and manoeuvrability? Bird and insect wings deform in flight, and have passively deployable structures such as feathers and flaps, but how do they exploit these features when aircraft designers shy away from aeroelasticity? Birds fly without a vertical tailfin, but how do they maintain yaw stability when most aircraft require one to fly safely? Questions such as these drive my research on bird and insect flight dynamics. My research is unique in using the engineering tools of flight dynamics and control theory to analyse physiological and biomechanical data from real animals. One research track will use measurements of the forces and torques generated by insects flying tethered in a virtual-reality flight simulator to parameterise their equations of motion, in order to model the input-output relationships of their sensorimotor control systems. A second research track will measure the detailed wing kinematics and deformations of free-flying insects in order to analyse the effects of aeroelasticity on flight manoeuvres. A third research track will measure the wing and tail kinematics of free-flying birds using onboard wireless video cameras, and use system identification techniques to model how these affect the body dynamics measured using onboard instrumentation. Applying these novel experimental techniques will allow me to make and test quantitative predictions about flight stability and control. This highly interdisciplinary research bridges the fields of physiology and biomechanics, with significant feeds to and from engineering. My research will break new ground, developing novel experimental techniques and theoretical models in order to test and generate new hypotheses of adaptive function. Its broader impacts include the public interest in all things flying, and potential military and civilian applications in flapping micro-air vehicles.;1954565;1954565;ERC-2007-StG;/ERC-SG;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;UK;;;"/BIO;/LIF;/MED";1;0;0;1;0;0 98505;275873;FANTI-SIZE;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-IEF;FP7;FAcilitated Niche creation Through Indirect interactions in SIZE structured ecological communities: Ontogenetic Asymmetries and Alternative-Stable-States;2011-07-01;2013-11-27;;'Under the emergent facilitation hypothesis, size-selective predators create a niche for another predator through facilitating the availability of previously scarce size-classes of prey by reducing competition amongst them. Emergent consumer facilitation has been proposed to give rise to Alternative Stable States (ASS) in species composition of ecological communities. There is a great deal of interest in ASS due to being linked to fisheries collapse and explaining biodiversity loss. The objectives of this proposal are to determine the likelihood of emergent consumer facilitation in an experimental aquatic food web with increasing biological realism, to generalise ecological theory of the role of facilitation in the dynamics of ecological communities and to determine the role of indirect facilitative interactions between consumers on the creation of, and shifts between, Alternative Stable Ecological Communities. This research will be undertaken using State-of-the-Art aquaria, mesocosm, modelling and whole lake approaches in a well studied boreal aquatic ecosystem in northern Sweden. The objectives are highly feasible and will be achieved through the establishment of a structured workplan and the strong science and complementary skills training by Professor Persson and his collaborators Professors De Roos and Diehl. Training objectives in experimentation, modelling and analysis linked to each scientific objective, are designed to increase my scientific maturity. And the mobility proposed is genuine, both in terms of geography, ecology and in exposure to new skills for both myself and the host research group (e.g. mesocosms, comparative analysis). Ultimately, the development of my track-record in the study of structured community dynamics, and the benefit of working with a world-class interdisciplinary research team will contribute to European excellence through advancing cutting-edge theory and comprehensive understanding of what creates biodiversity.';259565;259565;FP7-PEOPLE-2010-IEF;/MC-IEF;UMEA UNIVERSITET;SE;;;"/EMP;/EDU;/NET";1;0;0;1;0;0 108873;326974;Waste2bioHy;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IEF;FP7;Sustainable hydrogen production from waste via two-stage bioconversion process: an eco-biotechnological approach;2013-06-01;2015-05-31;;Among renewable H2-producing biotechnologies, dark fermentation (DF) of ”negative value” Organic Waste Streams (OWS) has received significant attention in recent years, since it combines sustainable waste management with pollution control and with the generation of a valuable clean energy product. Fermentative H2 production provides only a partial oxidation of the organic substrate, therefore, it is likely to be industrially viable only if integrated within a process that can utilize its end-products. Microbial Electrolysis Cell (MEC) is an emerging technology that could utilize the metabolic byproducts generated by DF to produce further H2. Combining DF with MEC in a cascade two-steps process can result in a complete exploitation of OWS, which maximizes at the same time energy recovery and effluent depollution. Although there is an intensive activity in optimizing process conditions through the variation of physicochemical factors, little research investigates the fundamentals of microbial interactions in such microbial ecosystems, that are at the basis of the conversion of organic matter to energy. Bridging the knowledge gap regarding the metabolic interactions within microbial fermentative/electrogenic communities could allow us to manipulate the microbial communities to maximize the efficiency of substrate conversion. This project adopts an interdisciplinary approach to deal with mixed cultures, from microbial engineering to microbial ecology and microbial physiology: this will establish new knowledge derived from microbial ecology, to the modern industrial and environmental biotechnologies. Besides the acquisition of fundamental knowledge on microbial metabolic interactions occurring in mixed cultures, the technical aim of the project is the development of a sustainable, cascade two-step BioH2 production process from OWS, combining DF and MEC. Such coupling of DF and MEC constitutes a technological cornerstone within the concept of an environmental biorefinery.;194046,6;194046,6;FP7-PEOPLE-2012-IEF;/MC-IEF;INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE;FR;;;/SCI;1;0;0;1;0;0 99263;274916;BILDE;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-IEF;FP7;How Can “Images Drive Out Images”? The Use and Function of Devotional Imagery in Heinrich Seuse’s Exemplar: A Reassessment;2011-07-01;2013-06-30;;"'The aim of this research and training programme is to provide new answers to art historical questions on the use and function of images in the meditative practices of the Late Middle Ages. I will do this by focusing on the highly problematic case of Heinrich Seuse’s Exemplar in an interdisciplinary way, combining Visual and Textual studies. For this reason I am applying to Leiden University Institute for Cultural Disciplines, which hosts a research group working on the mystical tradition of the Rhineland an the Low Countries (the Initial Training Network 'Mobility of Ideas and Transmission of Texts') and where, as an art historian, I will gain training in the fields of Medieval Textual studies and Manuscripts studies. Heinrich Seuse (†1366) was one of the most influential mystic writers in the Rhineland during the Middle Ages. In the Exemplar (a compilation of his texts accompanied by drawings he designed) Seuse offers a complex example of the relationship between text and images in the spiritual realm and a theory of devotional imagery based on a key phrase: “Drive out images with images”. Oft-quoted, but generally misunderstood, this concept needs to be reassessed in order to fully understand Seuse’s conception of devotional imagery. Scholars often state that for medieval mystics, images were important at the beginning of the meditative process but that they were simply tools to be left behind in order to move beyond the sensory world. Yet, with this phrase, Seuse offers a more subtle vision of this process: images should not be dispensed with entirely, instead each image must be replaced by another so that they complete and correct each other. This idea of continual interchanging modifies our understanding of the contemplative theory of the Exemplar. During this fellowship I will engage in the study of text-image issues and of the image theory in the Exemplar, in order to give a more accurate interpretation of the late medieval practice of religious meditation.'";168985,6;168985,6;FP7-PEOPLE-2010-IEF;/MC-IEF;UNIVERSITEIT LEIDEN;NL;;;"/EMP;/EDU;/NET";1;0;0;1;0;0 91204;237549;CULTURE AND RIGHTS;ONG;FP7-PEOPLE;FP7-PEOPLE-IEF-2008;FP7;Culture and Human Rights in Colombia: Negotiating Indigenous Law;2009-07-01;2011-06-30;;The research proposed over 24 months seeks to extend the ‘culture and rights’ debate in Social Anthropology through an ethnographic examination of how indigenous identity and self-image in Colombia is becoming politicised. The candidate intends to use the Fellowship significantly to advance her career by moving to a leading independent position in the field of socio-legal studies. The candidate’s foremost training activity under a dual mentorship comprises a programme of training-through-research on a personalized socio-legal project on Colombia. Through six months of ethnographic fieldwork at an indigenous law school, this research project reframes concepts of culture and rights by investigating indigenous leaders’ projection of indigenous culture as a basis for legal entitlements, the project’s suggestion is that in practice the terms ‘culture’ and ‘rights’ need not be inevitably opposed. The fellowship would provide the applicant with the opportunity to manage and implement an innovative interdisciplinary research project, developing skills and competencies through the facilities offered by the Department and the University of Cambridge.;;163702,68;FP7-PEOPLE-IEF-2008;/MC-IEF;THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;UK;;;"/SCI;/EMP";1;0;0;1;0;0 99663;271819;Crosstalk in GBMs;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-IOF;FP7;GENOMIC AND TRANSCRIPTIONAL ANALYSIS OF GLIOBLASTOMA MICROENVIRONMENTAL CELLULAR SUBSETS USING ANTIBODY MICROARRAYS;2011-10-01;2014-09-30;;The applicant is an experienced researcher with the objective of completing comprehensive training in translational research on Glioblastoma Multiforme (GBM), one of the most common malignant and lethal primary brain tumor of adults, with the final aim of disposing of personalized therapeutic protocols for GBM and cancer patients. The project is based on the finding that human tumors, particularly GBMs, are composed of a mixture of cancer, immune, stromal and vascular cells. The non-cancerous cellular components of the tumor microenvironment appear to play a critical role in tumor development and progression. At UCLA (Los Angeles, U.S.A.), the Mischel Lab has developed the DNA Encoded Antibody Library (DEAL) microarray, to sort specific cellular subtypes from solid tumor samples. The selective capture of tumor cells, lymphocytes, microglia and vascular endothelial cells, directly from GBM biopsy samples, will be obtained by DEAL technology. Genomic and transcriptional analysis will be performed on DEAL sorted cellular subtypes in order to identify novel molecular targets for therapeutic intervention. Genomic and transcriptional findings will be validated with functional assays in model systems: oncogene overexpression, gene silencing and pharmacological inhibition will be applied in order to identify the factors that inhibit the growth and survival of GBMs. In the first phase of the fellowship, at UCLA, the applicant will be utilizing cutting edge nanotechnology and resources that will provide her with outstanding interdisciplinary skills and competences. The applicant will then have the professional maturity to transfer her novel knowledge to the University of Verona (Italy), enriching the scientific excellence of Europe and bridging a new set of collaborations between Italy and the U.S.A.;230084,8;230084,8;FP7-PEOPLE-2010-IOF;/MC-IOF;UNIVERSITA DEGLI STUDI DI VERONA;IT;;;"/EMP;/SOC;/COO";1;0;0;1;0;0 87685;214936;ELCAT;ONG;FP7-PEOPLE;PEOPLE-2007-1-1-ITN;FP7;Surface Electrochemical Reactivity in Electrocatalysis: A combined Theoretical and Experimental Approach;2008-09-01;2012-08-31;;The aim of ELCAT is to train a new generation of young researchers in experimental and theoretical research methods in electrocatalysis. The scientific objectives are to address the problem of achieving specific reactivity in electrochemical transformations and to establish predictive tools based on quantum chemical calculations and computational modelling. The electrocatalytic properties of nanostructured metal and metal-oxide interfaces will be investigated using state of the art instrumental and experimental techniques. Four important electrochemical reactions have been chosen for their general importance in energy production, environmental control and clean chemicals production. Industrial participation in the Network will provide an understanding of the technological applications of electrocatalysis. The training objectives are to provide the young researchers with scientific skills as well as leadership qualifications to enable them to become established as independent researcherers in new areas thus providing an attractive vision for their research careers For this to be achieved, ELCAT will provide training by interdisciplinary research involving several laboratories, exchanges between laboratories having complementary expertise and instrumentation, participation in workshops and conferences and training by courses arranged by the Network in both scientific issues and complementary skills. This project is timely due to the present confluence of theoretical and instrumental research techniques of unprecedented power, such as new computational methods, a new understanding of electron transfer reactions at the nanoscale and advanced in-situ spectroscopies and Scanning Probe Microscopies. There are new industrial requirements derived from important societal issues resulting in an urgent need for a new generation of trained young researchers with a modern background in experimental and theoretical techniques for applications in electrocatalysis.;3135208;3135208;FP7-PEOPLE-2007-1-1-ITN;/MC-ITN;GOETEBORGS UNIVERSITET;SE;"UNIVERSIDAD DE ALICANTE;UNIVERSITEIT LEIDEN;UNIVERSITAET ULM;THE UNIVERSITY OF BIRMINGHAM;PERMASCAND AB;THE UNIVERSITY OF LIVERPOOL;USTAV FYZIKALNI CHEMIE J. HEYROVSKEHO AV CR, v. v. i.;JOHNSON MATTHEY PLC";"ES;NL;DE;UK;SE;CZ";"/EMP;/SOC;/EDU";1;0;0;1;0;0 108992;612484;NanoBioMat;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IRSES;FP7;Nanostructured Biocompatible/Bioactive Materials;2014-01-01;2017-12-31;;"The primary goal of the Joint Exchange Program (Project) is to create multicomponent materials for biomedical applications and to combine knowledge and experience of the different scientific groups concerning interdisciplinary milestones of the proposal in order to deliver the final product. In the framework of the Project the following materials: porous and nonporous silica oxides, nanostructured carbons, 3D reinforced polymers, metal containing composites and interpenetrating polymer networks, are scheduled to develop biocompatible/bioactive nanostructured materials. According to the programme, the research is focused on: surface modification and interfacial phenomena, structure-property relations, novel biocompatible/bioactive coatings for blood contacting surfaces, (entero)sorbents (for pollutants and (bio)toxins removal), and drug delivery system development. The partner’s panel is composed in regards to the Project goals and potential contributions. The consortium includes six partners, three of them are universities from Member States (P1-P3), and the Institute of Chemistry of the Academy of Sciences of Moldova (P4) is representing the Associated States. The Third Country Participants are presented by Partner 5, which comprised of teams from the Russian Academy of Sciences; and Partner 6 is the Chuiko Institute of Surface Chemistry of the National Academy of Sciences of Ukraine. This project will reinforce and strengthen existing bilateral scientific links and transforms them into a larger network which includes all the partners. It will provide momentum for long-term collaboration between the partners. Its results will lay foundation for other actions, aimed at further development and consolidation of the European Research Area and large scale competitive research projects. Additionally, this Project will provide relevant training for the early stage researchers from all teams.";319200;319200;FP7-PEOPLE-2013-IRSES;/MC-IRSES;UNIWERSYTET MARII CURIE-SKLODOWSKIEJ;PL;"INSTITUTUL DE CHIMIE ACADEMIA DE STIINTE A MOLDOVEI;UNIVERSITY OF BRIGHTON;NATIONAL TECHNICAL UNIVERSITY OF ATHENS - NTUA";"MD;UK;EL";/LIF;1;0;0;1;0;0 108831;328518;AGEWELL;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IEF;FP7;Ageing Migrants' Well-being: The Structuring of Local Welfare Provisions at the Intersection of Public, Private, Third Sector and the Family;2014-05-01;2016-09-15;;"The project’s scope is to advance the state-of-the-art research in the area of ageing migrants, local welfare regimes and care provisions. The project focuses on three dimensions: 1) local welfare policies with a focus on care for ageing migrants; 2) the role of the family as an informal care provider and 3) the care by ageing migrants. The results would serve to expand the knowledge base of local welfare policies capable to contribute to the well being of ageing migrants. Lately there has been increasing awareness that some migrants are reaching the retirement age at the destination and some people choose to migrate after retirement. Like in many other European countries, in Switzerland, occurs a rapid ageing of the migrant population. From the heterogeneous group of ageing migrants, two sub-groups will be chosen – labour migrants from after WWII and the refugees – which exist in many European countries. Particular attention will be given categories at risk: separated women and the ‘older old’. To address these interdisciplinary issues, the project will employ mixed-methods, combining qualitative and quantitative methods. There will be done a quantitative analysis of the ageing migrants population in Switzerland, there will be conducted interviews with ageing migrants and with local stakeholders in the welfare provisions in three selected regions, and there will be done a policy and institutional analysis of local policies with respect to care. The project conducts several comparisons – between ageing migrant groups and between regions – in order to underline differences and similarities, and explore the causalities leading to these outcomes. The expected results would be to 1) develop conceptual framework for analysing the evolving notion of welfare by focusing on the dynamics between public, private and third sector; 2) underline the contribution of ageing migrants in society and 3) explore the limitations of the family in welfare provisions.";184709,4;184709,4;FP7-PEOPLE-2012-IEF;/MC-IEF;UNIVERSITE DE GENEVE;CH;;;/SCI;1;0;0;1;0;0 90420;233204;COOPERATION;ONG;FP7-IDEAS-ERC;ERC-AG-LS8;FP7;Evolutionary explanations for cooperation: microbes to humans;2009-10-01;2015-09-30;;Cooperation poses a problem to evolutionary theory because it can be exploited by selfish individuals. Evolutionary biologists have developed a detailed theoretical overview of possible solutions to the problem of cooperation. In contrast to our theoretical understanding of potential solutions, however,, we have been relatively unsuccessful at applying theory to understand observations of cooperative behaviour nature. We present a novel and interdisciplinary programme of research to address this problem by empirically testing assumptions and predictions of several leading explanations for cooperation. We will develop theory to make explicit testable predictions for specific systems. We will exploit the advantage offered by different study systems: experiments with bacteria, comparative studies on cooperative breeding vertebrates, and experiments on humans. In addition to addressing specific hypotheses, we will show how evolutionary theory links and differentiates explanations for cooperation across various taxa and levels of biological organization.;1200000;1200000;ERC-2008-AdG;/ERC-AG;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;UK;;;"/BIO;/LIF";1;0;0;1;0;0 109116;334068;EMCHAHE;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-CIG;FP7;"""EARLY MEDIEVAL CHURCHES: HISTORY, ARCHAEOLOGY AND HERITAGE""";2013-07-01;2017-06-30;;"'This research project at the Institute of Heritage Sciences (INCIPIT) of the Spanish Council for Research (CSIC), aims to generate new scientific knowledge on the archeology and history of the early medieval rural churches and their value for cultural management in Galicia, in Northwest Spain. In this sense, this proposal aims to create a fruitful link between the applicant’s historical-archaeological research background and skills and the opportunities to learn and to develop a cultural heritage outreach project. At a historical level, churches will be here understood, beyond as mere physical constructions, like real vehicles and expressions of social interactions, at different levels, in the period of crutial changes between 5th and 11th centuries. All the evidences will be compilled, for the fist time, through an interdisciplinary methodology (archaeology, texts, places names... integrated in a GIS) and studied from a contextualized and comparative european perspective. Results will be disseminated by means of several impact publications. Regarding the heritage perspective this project aims to allow the applicant to learn how to re-direct all this knowledge towards a proper and effective management and comunication of the important and rather unknown heritage value of the remains of these buildings: architectural, archaeological (unearth or visible), artistic, documentary or even toponymic. Both objectives are interrelated since only an adequate historical knowledge allows for a correct heritage management.'";100000;100000;FP7-PEOPLE-2012-CIG;/MC-CIG;UNIVERSIDAD DE SANTIAGO DE COMPOSTELA;ES;;;/LIF;1;0;0;1;0;0 88477;212579;FOCUS-BALKANS;ONG;FP7-KBBE;KBBE-2007-2-1-02;FP7;Food Consumer Science in the Balkans: Frameworks, Protocols and Networks for a better knowledge of food behaviours;2008-10-01;2011-09-30;http://www.focus-balkans.org/;"The general objective of the FOCUS-BALKANS project is to improve competencies and understanding in the field of consumer food science in the Western Balkan countries (WBC). The scientific results of the research will make important contribution to the public health and consumer protection and to the achievement of the objectives within the FP7. The specific objectives are to: - Develop a network of universities, institutes, high schools, consumer organisations, NGOs and private enterprises active in the field of food consumer science with are able to develop joint-research activities; - Have a better understanding of food consumers in the WBCs, with a focus on products with positive nutritional properties (fruits and health / diet foods) and / or sustainability (organic and traditional food products). Formal training will be organised for key research organisations in the WBCs to enable them to become familiar with state of the art methodologies, practical techniques and theories. The training activities, organised in each WBC-country, target a wide range of organisations from the public and private research sectors, NGOs & consumer associations. 6 regional training meetings will be designed by the project partners and associated organisations. Four studies on niche markets plus one quantitative survey will systematically be conducted by WBC organisations as a mechanism for learning-by-doing. Two open seminars will bring together a wider spectrum of stakeholders including food supply chains representatives and policy-makers. Altogether, these actors will be invited to participate in the “Food Consumer Science Balkan Network”, which will seek to stimulate regional and interdisciplinary co-operation. The research, training and networking activities are intimately interlinked and will have strong synergies.";3043334,2;2614110;FP7-KBBE-2007-1;/CP-SICA;EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH;CH;"J.Z.U. INSTITUT ZA JAVNO ZDRAVJE NA REPUBLIKA MAKEDONIJA SKOPJE;UNIVERSITA DEGLI STUDI DI PARMA;INSTITUT D ENSEIGNEMENT SUPERIEUR ET DE RECHERCHE EN ALIMENTATION SANTE ANIMALE SCIENCES AGRONOMIQUES ETDE L ENVIRONNEMENT VETAGRO SUP;SOCIETE D'ETUDE POUR LE MARKETING, L'ENGINEERING ET LA GESTION;ZDRAVSTVENA USTANOVA INSTITUT ZA JAVNO ZDRAVLJE PODGORICA;EKONOMSKI FAKULTET, UNIVERZITET U BEOGRADU;SEEDEV DOO BEOGRAD;UNIVERSITY OF NEWCASTLE UPON TYNE;DEVELOPPEMENT DE L'AGRICULTURE ET DE L'ESPACE RURAL : AGRIDEA;STRATEGIC MARKETING DOO;WAGENINGEN UNIVERSITY;ECOZEPT GBR;UNIVERZA V LJUBLJANI;SVEUCILISTE U ZAGREBU EKONOMSKI FAKULTET;STICHTING WAGENINGEN RESEARCH;UNIVERZITET U BANJALUCI POLJOPRIVRE DNI FAKULTET";"MK;IT;FR;ME;RS;UK;CH;NL;DE;SI;HR;BA";"/SOC;/FOO";1;0;0;1;0;0 107301;331350;NEMCODE;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IEF;FP7;Controlled Assembly and Stabilisation of Functionalised Colloids in Nematic Liquid Crystals;2013-05-06;2015-05-05;;"'Herein I present a new approach towards 2D colloidal crystals with selectively created point and line defects. This project reaches beyond the state of the art in the field of colloidal crystals for photonic applications. However, in order to exploit these materials for photonic application point and line defects have to be created to guide light through the material. So far no bottom-up approaches to selectively created defects has been reported; in fact, despite the preparation of colloidal crystals usually involves self-assembly techniques the generation of point and line defects has been reached only using top-down techniques (i.e. photolithography, photochemical etching, focussed ion beam etching, etc.). The assembly will be carried out in reactive (polymerisable) liquid crystalline matrix by means of laser tweezers; UV-curing will cause the polymerisation of the reactive liquid crystal molecules yielding an aligned liquid crystalline network which will embed the assembly, stabilising it. Organic chemistry synthesis will be applied to generate photonitiator and polymerisable units to be installed on the surface of the colloids. The assembly technique reported by Prof. Muševiè will ensure a one-by-one construction of the colloidal crystals. Using this technique particles with a lower interaction with the generated polymeric network can be incorporated in specific position of the assembly. These particles can subsequently be removed by means of laser tweezers, generating point and line defects in the 2D colloidal crystal. The interdisciplinarity of the proposal which combines Organic Chemistry with Experimental Physics is one of the points of strength of the project. Positive outcomes will represent a leap forward for photonic and nanotechnology industry in the ERA. The host offers great opportunities to collaborate with industry allowing the EU to increase its level of competition with other producers of this kind of photonic materials.'";154137,6;154137,6;FP7-PEOPLE-2012-IEF;/MC-IEF;INSTITUT JOZEF STEFAN;SI;;;/SCI;1;0;0;1;0;0 89606;207326;AMPA PHOSPHORYLATION;ONG;FP7-PEOPLE;PEOPLE-2007-4-3.IRG;FP7;MOLECULAR MECHANISMS OF APPETITIVE ASSOCIATIVE MEMORY;2007-10-01;2011-09-30;;"AMPA receptors mediate the majority of fast excitatory neurotransmission in the vertebrate nervous system and recent evidence has implicated AMPA receptor regulation in long-term potentiation (LTP) and long-term depression (LTD), cellular models of learning and memory. However, experimental evidence connecting synaptic plasticity and learning and memory remains scarce. Such evidence comes from demonstrations that behavioral performance on learning and memory tasks is impaired with manipulations of a molecular target in a relevant neural circuit. The present proposal aims to use an integrated and interdisciplinary approach, combining molecular, systems and behavioral neuroscience approaches, to investigate the role of AMPA receptor phosphorylation processes in incentive learning and memory. The specific aims of the proposal are: 1) to develop behavioral models to probe critical subprocesses involved in incentive learning and to test mice with point-mutations of AMPA-GluR1 Ser 831 and 845 phosphorylation sites on these tasks; 2) to use viral-vector mediated gene transfection to determine whether recovery (or rescue) of GluR1 phosphorylation in select brain regions will recover incentive learning processes; and 3) to study the role for GluR1 phosphorylation in the long-term effects of psychoactive drugs of abuse on incentive learning. By combining state-of-the-art molecular genetics approaches with advanced behavioral modeling to parse psychological processes that contribute to incentive learning, the experiments proposed are expected to yield new insights into the molecular basis of learning and memory, in particular incentive learning and memory. Such insights are important, as incentive learning processes play a vital role in many adaptive behaviors, as well as maladaptive conditions, such as eating disorders and drug addiction.";100000;100000;FP7-PEOPLE-2007-4-3-IRG;/MC-IRG;THE UNIVERSITY OF SUSSEX;UK;;;"/SCI;/COO";1;0;0;1;0;0 96227;263183;FAMINE;ONG;FP7-IDEAS-ERC;ERC-SG-SH2;FP7;Families of Inequalities- Social and economic consequences of the changing work-family equilibria in European Societies;2010-12-01;2014-11-30;;"This project investigates social change and its correlates in European societies. In specific, the change in social and economic inequalities associated with new welfare-work-family equilibria. The Project therefore focuses on the changes in women s labour market behaviour, the interlinkage between women s employment and family decisions, families’ capacities to compensate for increasing market risks and the consequences of these developments for social and economic inequalities between families in post industrial societies over recent decades, considering the role of the different welfare and labour market arrangements and the way they evolved. It focuses on the new welfare-work-family equilibria analysing the social and economic consequences of these (dis) equilibria for European societies and their capacity to fully integrate their populations, assuring decent employment conditions, adequate social rights and full social participation. It does so in a strict international comparison, following an interdisciplinary approach between sociology, economics and demography and applying leading edge quantitative methods to adequately treat topics in life cycle perspective.";478494;478494;ERC-2010-StG_20091209;/ERC-SG;UNIVERSITA DEGLI STUDI DI TRENTO;IT;;;/SOC;1;0;0;1;0;0 105775;314678;EFFESUS;ONG;FP7-ENVIRONMENT;EeB.ENV.2012.6.6-2;FP7;ENERGY EFFICIENCY FOR EU HISTORIC DISTRICTS SUSTAINABILITY;2012-09-01;2016-08-31;http://www.effesus.eu/;"Europe can become the leader in CO2 emission reduction by applying innovative solutions to its built cultural heritage. According to the European Recovery Plan one of the actions that needs to be taken to tackle the current crisis, is investing in energy efficiency. Historic urban buildings consume 4% of all energy and are responsible for 3% of CO2 emissions. Therefore, improving energy efficiency in historic buildings and historic districts is essential. Nevertheless, most of the current developments in energy efficiency address new construction without dealing with the unique problems of historic structures. A number of technologies and products have been developed, however many of the solutions are not acceptable for historic structures due to the necessity of preserving integrity and authenticity. Therefore, the main goal of EFFESUS is to develop and demonstrate, through case studies a methodology for assessing and selecting energy efficiency interventions, based on existing and new technologies that are compatible with heritage values. A Decision Support System will be a primary deliverable. The environment in historic buildings and urban districts is controlled differently from modern cities and accordingly the project will also develop a multi-scale data model for the management of energy. In addition, new non-invasive, reversible yet cost-effective technologies for significantly improving thermal properties will also be developed. Finally, existing regulations and building policies may not fit cultural heritage specificities so the EFFESUS project will also address these non-technical barriers. These outcomes will be achieved through 10 work packages, performed by an interdisciplinary consortium of 23 partners from 13 countries. Due to the attractiveness of this niche market, 36 % of the project budget is allocated to SME’s, which will work together with large companies, research institutions and end users throughout the duration of the project.";6786903,26;4988422;FP7-2012-NMP-ENV-ENERGY-ICT-EeB;/CP-TP;FUNDACION TECNALIA RESEARCH & INNOVATION;ES;"CONSORCIO DE LA CIUDAD DE SANTIAGO DE COMPOSTELA;OLOKLIROMENA PLIROFORIAKA SISTIMATA;Active Space Technologies, Actividades Aeroespaciais S.A.;R.E.D. SRL;PROIGMENES EREVNITIKES & DIAHIRISTIKES EFARMOGES;FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.;SNEKKERIET VERDAL AS;UPPSALA UNIVERSITET;RINA CONSULTING SPA;HOGSKOLAN PA GOTLAND;ACCADEMIA EUROPEA DI BOLZANO;CONSIGLIO NAZIONALE DELLE RICERCHE;DELAP & WALLER ECOCO LIMITED;RODWELL DENNIS GRAHAM;ACTIVE AEROGELS LDA;HISTORIC ENVIRONMENT SCOTLAND;GOUAS FRANCIS;UNIVERSITAET STUTTGART;SAS GOUAS;BOFIMEX BOUWSTOFFEN BV;HOR-BER BERUHAZASI TANACSADO ES TERVEZO MERNOKIRODA KFT;NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU;ACCIONA CONSTRUCCION SA;SAMPAS NANOTEKNOLOJI ARASTIRMA GELISTIRME VE PAZARLAMA LIMITED SIRKETI;A. PROCTOR GROUP LIMITED;SCOTTISH GOVERNMENT";"ES;EL;PT;IT;DE;NO;SE;IE;UK;FR;NL;HU;TR";/SCI;1;0;0;1;0;0 185374;336045;CHROMOTHRIPSIS;ONG;FP7-IDEAS-ERC;ERC-SG-LS2;FP7;Dissecting the Molecular Mechanism of Catastrophic DNA Rearrangement in Cancer;2014-04-01;2019-01-31;;"Recent cancer genome analyses have led to the discovery of a process involving massive genome structural rearrangement (SR) formation in a one-step, cataclysmic event, coined chromothripsis. The term chromothripsis (chromo from chromosome; thripsis for shattering into pieces) stands for a hypothetical process in which individual chromosomes are pulverised, resulting in a multitude of fragments, some of which are lost to the cell whereas others are erroneously rejoined. Compelling evidence was presented that chromothripsis plays a crucial role in the development, or progression of a notable subset of human cancers – thus, tumorigensis models involving gradual acquisitions of alterations may need to be revised in these cancers. Presently, chromothripsis lacks a mechanistic basis. We recently showed that in childhood medulloblastoma brain tumours driven by Sonic Hedgehog (Shh) signalling, chromothripsis is linked with predisposing TP53 mutations. Thus, rather than occurring in isolation, chromothripsis appears to be prone to happen in conjunction with (or instigated by) gradually acquired alterations, or in the context of active signalling pathways, the inference of which may lead to further mechanistic insights. Using such rationale, I propose to dissect the mechanism behind chromothripsis using interdisciplinary approaches. First, we will develop a computational approach to accurately detect chromothripsis. Second, we will use this approach to link chromothripsis with novel factors and contexts. Third, we will develop highly controllable cell line-based systems to test concrete mechanistic hypotheses, thereby taking into account our data on linked factors and contexts. Fourth, we will generate transcriptome data to monitor pathways involved in inducing chromothripsis, and such involved in coping with the massive SRs occurring. We will also combine findings from all these approaches to build a comprehensive model of chromothripsis and its associated pathways.";1471964,05;1471964,05;ERC-2013-StG;/ERC-SG;EUROPEAN MOLECULAR BIOLOGY LABORATORY;DE;;;"/BIO;/LIF";1;0;0;1;0;0 98736;275604;knowledge flows;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-IEF;FP7;Knowledge flows within emerging multinationals: the case of subsidiaries of Latin multinationals in Europe;2011-06-01;2014-07-25;;"Firms from emerging countries are increasingly expanding their global presence by directly investing abroad and becoming multinationals on their own right. Those so-called emerging multinationals (E-MNCs) are gaining space in the global business arena, largely dominated by multinationals from the triadic countries. Studies so far have focused on the factors driving E-MNCs to engage in foreign direct investment. A central issue is whether the E-MNCs possess competitive advantages that can be exploited abroad, or if they are in fact seeking for acquiring and developing such advantages overseas. This research proposal intends to bridge a gap in the research on E-MNCs by focusing on the European subsidiaries of Latin American MNCs (LA-MNCs). It addresses the question of how multinationalisation of developing countries’ firms affects innovation and knowledge flows within them, and between them and their host economies. Our objective is to identify the patterns of knowledge flows to and from the European subsidiaries of LA-MNCs by analyzing the exchange of knowledge between them and: 1) their headquarters, and 2) host economies. The main expected outcome of this study is the understanding of to what extent the European subsidiaries of LA-MNCs: 1) send knowledge to and receive knowledge from their parent headquarters in Latin America; and 2) source in and contribute with positive spillovers to the knowledge base of their European hosts. This research proposal deals with highly complex phenomena, innovation and multinational corporations; it is interdisciplinary and multidisciplinary in essence, and integrates concepts and methods from several fields of economics and international business. The methodological approach combines different methods and sources of information. We will carry out both a survey of headquarter of LA-MNCs and multi-case studies of European subsidiaries of LA-MNCs; and rely on both primary and secondary sources of quantitative and qualitative data.";262936,8;262936,8;FP7-PEOPLE-2010-IEF;/MC-IEF;UNIVERSITY OF BRIGHTON;UK;;;"/EMP;/EDU;/NET";1;0;0;1;0;0 96017;253716;MMRTSB;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IEF;FP7;Matrix Models Recursions in Topological Strings and Beyond;2010-10-01;2012-09-30;;"Recently it has appeared that recursions relations formulated in the context of matrix models can be applied to solve a wide array of problems ranging from topological string theory to algebraic geometry to statistical physics. It has also been shown that matrix models recursions are sometimes equivalent to other known recursions developed to solve several algebro--geometric problems. Matching recursions belonging to different areas has very deep conceptual implications pointing to the existence of some hidden universal property of solvable problems which would explain the broad applicability of matrix model technologies. In this research project several problems will be addressed with these new tools, from mostly mathematical to more physical ones. On the more formal side matrix models technologies will be employed in topological strings and algebraic geometry, fields where the profitability of these methods is by now well established. On the physics side more explorative researches will be carried out mostly in the context of the AdS/CFT duality and in the computation of gluon scattering amplitudes. This interdisciplinary project is expected to be a means for knowledge transfer between the mathematics and string theory communities. The training proposed in this project aims at enhancing all aspects of the applicant's capability to perform leading independent research.";165040,8;165040,8;FP7-PEOPLE-2009-IEF;/MC-IEF;QUEEN MARY UNIVERSITY OF LONDON;UK;;;"/SCI;/EDU;/ITT";1;0;0;1;0;0 99361;273193;MM of LE in EME;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-IIF;FP7;Molecular mechanisms underlying the lineage establishment in the early mouse embryo;2011-07-01;2013-06-30;;"Early mammalian development is characterized by formation of the blastocyst, composed of the pluripotent inner cell mass surrounded by a one-cell layer of epithelial cells, the trophectoderm. Despite its importance for understanding mammalian development and for stem cell research, the mechanism of blastocyst morphogenesis and patterning has long been elusive and a subject of controversy. The ultimate goal of this project is to understand the molecular mechanism of the lineage establishment in the mouse blastocyst. To this end, functional screens will be performed to identify players essential for the lineage specification. Those gene sets specifically expressed in each cell lineage will be characterized by single-cell gene expression profiling methods. Functional screens will be performed using a subset of siRNA libraries directed against each gene set in order to identify key molecules for the blastocyst differentiation. Here, fluorescent reporter lines established in the host laboratory will serve as a unique reference for the read-out of molecular dynamics during embryonic patterning. Alternatively, among those gene sets, potential candidate molecules will be first identified by focusing to the upstream players and small RNAs in signaling cascades in the lineage specification. Their function will then be analyzed by siRNA-mediated knock-down. Thus, these findings will provide a mechanistic model underlying the lineage establishment in the early mouse embryo. Taken together, the project will provide not only an insight into the pluripotency in vivo but a basis for an interdisciplinary approach for stem cell research and regenerative medicine. It is likely that the techniques established in the project will serve as a unique tool for embryonic development research and will result in a long lasting fruitful collaboration.";170363,2;170363,2;FP7-PEOPLE-2010-IIF;/MC-IIF;EUROPEAN MOLECULAR BIOLOGY LABORATORY;DE;;;"/SOC;/COO";1;0;0;1;0;0 109281;607774;ADVANTAGE;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-ITN;FP7;ADVanced communicAtions and iNformaTion processing in smArt Grid systEms;2014-01-01;2017-12-31;;'Smart Grid systems represent a significant new technology to provide more energy efficient power delivery systems that reduce carbon emissions and can handle a mix of energy sources from small scale renewable energy to large power stations. The design and implementation of the smart grid will be very complex, involving a large number of systems, layers and relationships. In order to make the infrastructure of smart grid systems work effectively, engineers need to be trained to have a detailed understanding of both power engineering and communications issues. Many related research projects to date involve either mainly power engineers or mainly communications/signal processing researchers, limiting the interaction and knowledge exchange between these two communities. However, smart grid engineers should be able to appreciate the power network that the smart grid is designed for and how to communicate and process data concerning the power grid, so that it can be controlled effectively. This ITN project is a major interdisciplinary project between both power and communications engineers to train the next generation of engineers and scientists that will lead the development of this technology both within Europe and Internationally.';3596493,78;3596493,78;FP7-PEOPLE-2013-ITN;/MC-ITN;THE UNIVERSITY OF EDINBURGH;UK;"UNIVERZITET U NOVOM SADU FAKULTET TEHNICKIH NAUKA;CENTRE TECNOLOGIC DE TELECOMUNICACIONS DE CATALUNYA;FLEXITRICITY LIMITED;SCHNEIDER ELECTRIC DMS NS DOO ZA ELEKTROENERGETSKI INZINJERING NOVI SAD;NEOGRID TECHNOLOGIES APS;AALBORG UNIVERSITET;UNIVERSIDAD DE SEVILLA";"RS;ES;UK;DK";/LIF;1;0;0;1;0;0 108679;316097;ENGINE;ONG;FP7-REGPOT;REGPOT-2012-2013-1;FP7;European research centre of Network intelliGence for INnovation Enhancement;2013-06-01;2016-11-30;;The ENGINE Centre is an interdisciplinary research unit of the Wroc³aw University of Technology, specializing in so-called Network Intelligence. This term spans the development of innovative, intelligent and advanced tools for effective computing, smart decisions and intelligent human-computer interactions applied in medicine, natural sciences, sociology and psychology, management and economics, mobile entertainment, business and industrial solutions, with special emphasis on SMEs. Despite quite substantial funds allocated in the last years to the ENGINE Centre, its organizational and scientific level has not been attained yet comparable to that of leading research institutions in the European Research Area, first of all due to insufficient funds, lack of adequate staff trainings and unsatisfactory collaboration with external scientific and industrial partners. The crucial idea behind the ENGINE project is to significantly enhance the research potential of the ENGINE Centre by employment of new external reputed researchers, upgrading the laboratory’s equipment, and strengthening the know-how exchange of advanced and innovative research on networked intelligence. The main objectives of the ENGINE project are: (i) enhancement of staff abilities, (ii) better integration with ERA, (iii) improvement of existing technical capabilities, (iv) strengthening the long-lasting partnership with European research centres. The ENGINE project will also ensure to establish strong and lasting collaboration with industrial and governmental partners, including SMEs, for mutual benefits resulting in knowledge transfer and competitive future in cutting-edge scientific activities. The project will also help to achieve the sustainable development of the ENGINE Centre research quality, competitiveness and attractiveness, at the regional, national, European and worldwide level.;4731186,8;4245000;FP7-REGPOT-2012-2013-1;/CSA-SA;POLITECHNIKA WROCLAWSKA;PL;;;/SCI;1;0;0;1;0;0 101561;290022;ESTABLIS;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-ITN;FP7;Ensuring STABiLIty in organic Solar cells;2012-01-01;2015-12-31;http://www.project-establis.eu/;"The Earth receives the energy in 1 hour required for all human needs in a year. Harvesting solar energy will reduce harmful CO2 emissions and resolve the forthcoming energy deficit that other sources alone cannot make up. The market for stable, cheap, roll-to-roll mass-produced organic solar cells (OSCs) is estimated at 1 billion Euros by 2016. The ITN ESTABLIS will produce a team of 11 ESRs and 4 ERs to harness this pivotal point in Europe’s development based on a reliable, economically powerful and clean resource. ESTABLIS will be an interdisciplinary and inter-sectorial research and training network. ESRs and ERs that result from ESTABLIS will excel. They will possess a broad skill-set across a range of disciplines that are of absolute necessity to develop the industrial and academic infra-structure in OSCs. Researchers will receive training in the primary areas of synthetic organic chemistry through complementary aspects of polymer science to complete industrial scale photovoltaic device manufacture. To improve the roll-to-roll engineering and stability of opto-electronically active thin-films will require new polymers, surface treatments, rheological appraisals of polymer processing, and ageing studies. A parallel approach will develop the necessary improvements in electronic and opto-electronic properties by clarifying correlations between charge transfer, photochemistry and stability. This project will be run by meticulously interacting groups to increase the stability of strong, flexible, low-cost OSCs to 10 years so that they can be sold on a mass-market basis. ESTABLIS is an exceptionally complementary consortium of field-leading University groups and the world’s chief Industrial companies, namely, the world’s foremost producers of OSCs, Konarka, of conducting polymers, Heraeus, and of semiconducting polymers, Merck. These key European companies are at the heart to ensure that training and technological developments will be industrially operable.";3870292,89;3870292,89;FP7-PEOPLE-2011-ITN;/MC-ITN;UNIVERSITE DE PAU ET DES PAYS DE L'ADOUR;FR;"BELECTRIC OPV GMBH;MERCK CHEMICALS LTD;UNIVERSITAT LINZ;MEDZINARODNE LASEROVE CENTRUM;VILNIAUS UNIVERSITETAS;KONARKA TECHNOLOGIES GMBH;HERAEUS PRECIOUS METALS GMBH & CO. KG;FUNDACION IMDEA NANOCIENCIA;EBERHARD KARLS UNIVERSITAET TUEBINGEN;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;ASTON UNIVERSITY";"DE;UK;AT;SK;LT;ES;FR";"/LIF;/SCI";1;0;0;1;0;0 109273;606734;COSSHNET;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-ITN;FP7;Complementary Synthetic Strategies toward Heterocyclic Boronates;2014-01-01;2017-12-31;;'COSSHNET is a dual-partner Industrial Doctorate (EID) offering research training in state-of-the-art chemical synthesis, catalysis, bioactive molecule design and high throughput library synthesis. Through integration of the complementary, interdisciplinary and intersectorial expertise of the partners, this network will help to strengthen Europe’s human resources in the fine chemical and pharmaceutical industries. The researchers will be supervised and mentored by internationally recognised experts and have access to state-of-the-art equipment. Hands-on training will be supplemented by formal training courses in relevant and related fields, and a wide variety of complementary training courses, summer school and seminars. Researchers will benefit from secondments to the industrial partner for a significant period of the project, thereby gaining extensive exposure to a commercially based scientific environment. Overall, it is anticipated that the COSSHNET project will provide both Early Stage Researchers (ESRs) with an outstanding training experience, through extensive technical and complementary skills development.';587133,58;587133,58;FP7-PEOPLE-2013-ITN;/MC-ITN;THE UNIVERSITY OF SHEFFIELD;UK;SANOFI-AVENTIS DEUTSCHLAND GMBH;DE;/LIF;1;0;0;1;0;0 95079;256435;PA_EXP_EVOL;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-RG;FP7;Siderophore production in the human pathogen Pseudomonas aeruginosa: a model trait to study the evolution of cooperation and virulence;2010-07-01;2013-06-30;;"The occurrence of cooperation is one of the greatest challenges for evolutionary biology. The problem is why should an individual carry out a cooperative behaviour that is costly to perform, but benefits other individuals? The theoretical framework of inclusive fitness has proofed extremely successful in explaining the evolution of cooperation across a wide number of taxa ranging from microbes to mammals. Particularly, the investigation of microbial cooperative systems have opened a completely new research area because microbes allow observing the evolution of cooperation in real-time. Furthermore, many cooperative traits are involved with virulence in infections of humans, and have therefore medical relevance. Consequently, the research in this area is highly interdisciplinary connecting the fields of evolutionary biology, microbiology and medicine. This proposal focuses on the production of siderophore molecules in the opportunistic human pathogen Pseudomonas aeruginosa. Iron is a major limiting factor for bacterial growth and in response to iron deficiency, P. aeruginosa releases siderophore molecules into the local environment to scavenge insoluble iron, making it available for bacterial metabolism. Siderophore production is a cooperative behaviour as it can provide a fitness benefit to neighbouring cells, which can take up iron bound to siderophore produced by others. This proposal uses cooperative siderophore production to study: (i) the properties of siderophore molecules as a cooperative good and virulence factor, and assess the fitness consequences for cooperative wildtype and non-cooperative mutant strains in mixed cultures in vitro and in animal host models; (ii) the dynamics of cooperative and non-cooperative strains under different environmental conditions as they may occur in nature; and (iii) the adaptive responses of cooperators to the presence of non-cooperative strains at the behavioural and genetic level in an experimental evolution set up.";45000;45000;FP7-PEOPLE-2009-RG;/MC-ERG;EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH;CH;;;/SCI;1;0;0;1;0;0 108520;324198;MODERNMOVES;ONG;FP7-IDEAS-ERC;ERC-AG-SH5;FP7;Modern Moves: Kinetic Transnationalism and Afro-Diasporic Rhythm Cultures;2013-06-01;2018-05-31;;"'The movement of Africans and Europeans to the Americas through expansionism, colonialism, and slavery also brought to the New World African percussive rhythms and European musical instruments and courtly dances. This project investigates the social dances that evolved out of this encounter, and retained African rhythm structures and body movement in American and Caribbean diasporic spaces. Under transnational conditions, Afro-diasporic social dances such as Swing, Mambo, Salsa, and Zouk have been diffused through Europe, Asia and back to Africa. Indeed, from the 1920s onwards, people the world over, often disconnected from African cultures, have used dances marked by 'African' traces to fashion themselves as modern subjects. The project will examine these 'modern moves' and their transnational developments, to argue that Afro-diasporic rhythm cultures, as manifested in these transnationalised dances, are intrinsic to global modernity. An interdisciplinary research team, led by the coordinator, will study their kinetic dimension: how specific dance steps evolved in correspondence to musical styles; the sites for their enjoyment and proliferation; song lyrics as sites of memory; and the socio-historical conditions under which these dance styles are assimilated into competing rhythm cultures, from 'Bollywood' to the dance fitness craze 'Zumba'. Moving away from Postcolonial Studies' reliance on textuality to highlight bodily pleasure and spectacularity, we will investigate ‘AfroPolitanism’—the nourishing of these social dances in urban spaces-- and ask how and why Afro-diasporic rhythms connect ‘AfroPolitans’ from postcolonial worlds that speak different languages and have inherited divergent colonial histories. The category of 'kinetic transnationalism' will guide our analysis of modernity's moves, from intra-community preservation to transnational affiliations, while revealing the place of Africa and the 'AfroPolitan' in the history of modernity.'";2209667,92;2209667,92;ERC-2012-ADG_20120411;/ERC-AG;KING'S COLLEGE LONDON;UK;;;/SOC;1;0;0;1;0;0 108495;332274;FISH ALLERGOMICS;CAN;FP7-PEOPLE;FP7-PEOPLE-2012-IEF;FP7;PROTEOMICS AND SYSTEMS BIOLOGY OF FISH ALLERGY;2013-06-01;2015-05-31;;"'Food allergy is considered one of the major concerns in food safety. The prevalence of this type of IgE-mediated allergy has been increasing during the last two decades (6-8% of children/2-4% of adults). Fish is one of the most frequent causes of this type of allergy. The symptoms appear within 60 min of exposure and include acute urticaria, nauseas, wheezing and asthma. In the most severe cases, anaphylaxis shocks can potentially life threatening. To guarantee consumers security, a number of regulations in terms of food allergy have been implemented (Directive 2007/68/EC). In addition, the recent scientific opinion of the European Food Safety Authority recognized the current high risk throughout the world and identified the necessity of developing new methods to detect, monitor and control this problem. In this sense, Fish Allergomics is an interdisciplinary and multidisciplinary project, where the Advanced Proteomics and Proteomics-based Systems Biology approaches, will be apply to guarantee the safety to the consumers in terms of fish allergy. Three main directions/applications will be performed: - Food Safety Control (Targeted Proteomics) - Immunotherapy (Peptidomics and De Novo MS sequencing) - In Silico model of fish allergy (Proteomics-based Systems Biology) The combination of these three goals will provide: (i) a valuable method for the control authorities and food industry to guarantee the safety to the consumers, (ii) reliable information for the design of new synthetic peptide-vaccines and (iii) the generation of a holistic map of T-cell signalling for fish allergy, helpful to identify new relevant targets for pharmacologic or therapeutic interventions.'";166336,2;166336,2;FP7-PEOPLE-2012-IEF;/MC-IEF;AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS;ES;;;/SCI;1;0;0;1;0;0 101520;287091;LOG4GREEN;ONG;FP7-REGIONS;REGIONS-2011-1;FP7;Transport Clusters Development and Implementation Measures of a Six-Region Strategic Joint Action Plan for Knowledge-based Regional Innovation;2011-12-01;2014-11-30;;"LOG4GREEN's objective is to boost the regional competitiveness and growth in six European regions: Carinthia (AT), Ruhr (GE), Wallonia (BE), Normandy (FR), Istanbul (TR), Odessa (UA). Logistics clusters of these regions have joined forces to elaborate and to start the implementation of a Joint Action Plan. LOG4GREEN considers the characteristics of Sustainable Transport Logistics such as: (i) logistics is genuinely defined by a need for interaction and qualified communication, (ii) logistics is a key factor for the greening of transport, (iii) the role of logistics is underestimated and needs public awareness to support an overall development towards more sustainability. 4 general objectives within the RTD-based logistics sector have been defined and transformed into a 36 months workplan: (1) to strengthen integrative research in the overall field of logistic systems by developing transregional interdisciplinary RTD-networks involving stakeholder groups along the value-added chain, (2) to foster interregional knowledge exchange between the triple helix stakeholders making use of the challenges/best practices for green transport in order to open up new fields for research activities, (3) to optimise education and training of (young) experts to meet the challenges of the highly complex multidisciplinary requirements of the future logistics innovation systems, (4) to enhance the competitive performance of the European logistics clusters with regard to the development of successful regional RTD- and knowledge transfer structures in global context. The partnership builds upon existing bilateral cooperation between partner regions, promotes synergies but also identifies complementarities in both research and economic fields. The consortium further improves existing links between the actors involved and stakeholders in clearly defined mentoring regions. The project thus supports the development (or foundation) and internationalisation of regional research-driven cluster.";2840856,4;2544574;FP7-REGIONS-2011-1;/CSA-CA;PROJEKTKOMPETENZ.EU - GESELLSCHAFT FUR PROJEKTENTWICKLUNG UND -MANAGEMENT MBH;AT;"ULUSLARARASI NAKLIYECILER DERNEGI;KOLMYKOVA UND NACK GBR;BIMTAS BOGAZICI PEYZAJ INSAAT MUSAVIRLIK TEKNIK HIZMETLER SANAYI TICARET ANONIM SIRKETI;NOV@LOG ASSOCIATION;ODESSA NATIONAL MARITIME UNIVERSITY;UNIVERSITAET DUISBURG-ESSEN;EFFIZIENZCLUSTER MANAGEMENT GMBH;KOC UNIVERSITY;PROJEKTkompetenz.eu OG;LOGISTICS IN WALLONIA;UNIVERSITAET KLAGENFURT;ENTWICKLUNGSAGENTUR KARNTEN GMBH;NETZWERK LOGISTIK";"TR;DE;FR;UA;AT;BE";"/ECO;/SDT";1;0;0;1;0;0 108250;329548;EuroMoroccanScience;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IEF;FP7;Circulating modernity: the role of student missions sent to Europe in the scientific and social modernization of pre-colonial Morocco (1873-1912);2013-06-01;2015-08-31;;"The proposed project will analyze the scientific and social modernization of pre-colonial Morocco resulting from the circulation of young medical, scientific and engineering students in Europe in the period 1873-1912. This general aim will be achieved by: I. Mapping the identity, family background, social extraction and previous education of Moroccan students; II. Determining the actual scientific education and training they received in various European host institutions. III. Determining the context and actual impact of their re-insertion in Morocco. IV. Establishing the contribution of European-trained scientists to Moroccan nationalist and anti-colonialist movements. Four case-studies will be considered, corresponding to student missions sent by the Moroccan government to institutions of Great Britain, France, Spain and Italy. Methodologically, this project is strongly interdisciplinary, combining approaches from the history of science, history of education, colonial history and modernization theory. It follows a tradition of prosopographic studies, though further develops it through a circulation perspective. It also breaks the scholarly tendency to work exclusively on idealized knowledge by focusing on person-oriented and practice-oriented research. Finally, it intends to promote a greater internationalism by analyzing and comparing several national settings. The project's relevance stems from its being a strong historical example able to inform reflection on the design of current European cooperation policies in science & technology development and democratization in Mediterranean partern countries. It will also raise public awareness on the long-running importance and impact of European scientific expertise in the world. Lastly, it will be in tune with current challenges in the field of history of science: the need of understanding scientific research and practice in a circulatory and global perspective";194046,6;194046,6;FP7-PEOPLE-2012-IEF;/MC-IEF;UNIVERSITE PARIS DIDEROT - PARIS 7;FR;;;/SCI;1;0;0;1;0;0 108997;328075;ASEC-DRYLAND-FORESTS;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IEF;FP7;Avoiding the socio-ecological collapse of remnant evergreen forests in drylands: the case study of northern Kenya;2014-06-01;2016-05-31;;"One in five people in the world live in already degraded or desertification-prone drylands. Evergreen remnant forests in drylands provide essential livelihood resources to surrounding communities. However, these type of forests remain understudied and over-exploited. Predicted climatic changes and trends in population growth will negatively affect the ecological functioning and ecosystem service (ES) delivery of these already fragile ecosystems. Therefore, there is an urgent need to better understand and manage these ecosystems. ASEC-Dryland-Forests, focused on three forests in northern Kenya, will provide new information key for understanding and improving the management of these type of ecosystems. ASEC-Dryland-Forests will combine remote sensing data, meteorological and water availability time-series data, ground measurements (forest structure, carbon), local perceptions of importance, value, availability and change of ES (participatory approach), modelling and novel state-of-the-art methodologies from the fields of ecology, conservation science and socio-economics to (1) identify, measure and value the ES provided by the forests; (2) reveal the inter-relationship between isolated forests, climate and water at a local scale; (3) determine if current ES use is sustainable; and (4) develop management strategies for future sustainability. ASEC-Dryland-Forests is a highly interdisciplinary project which will generate information of wide relevance for the sustainable use of natural resources in dryland pastoralist communities both in Africa and in similar environments worldwide. The relevance and the high scientific quality proposed will benefit the EU not only by generating new knowledge and publications in high-profile scientific journals which will contribute to the enhancement of EU scientific excellence, but also by contributing to EU commitments within International treaties such as the Combat Desertification Agreement and the Millennium Development Goals.";221154,6;221154,6;FP7-PEOPLE-2012-IEF;/MC-IEF;KOBENHAVNS UNIVERSITET;DK;;;/SCI;1;0;0;1;0;0 104040;302228;iTRIS;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IEF;FP7;Interaction Trichoderma-Stenotrophomonas and its effect on plant growth and health;2013-06-01;2015-05-31;;"The use of beneficial microorganisms to suppress plant diseases has become a reliable alternative to reduce the application of pesticides. There is a strong growing market for microbial inoculants worldwide with an annual growth rate of approximately 10%. The use of ‘Omic technologies leads to products with more predictable and consistent effect. The future success of biological control will depend on interdisciplinary researches about the ecological interactions taking place in soil and root environment. Aim of the present research is to gain insight on the interaction between biological control agents (BCAs) and to assess its potential synergistic effect on suppression of the fungal pathogen Verticillium dahliae and on plant growth and health. The protagonists of the research are one of the most important beneficial fungus for agriculture, Trichoderma velutinum G1/8 and one of the most promising candidate for application as a BCA and plant growth promotion, the bacterium Stenotrophomonas rhizophila DSM14405T. Character of absolute innovation is the assessment of the role played by secondary metabolites and volatile organic compounds (VOCs) in the interaction between the BCAs, between the BCAs and the pathogen and between the BCAs and the plant. Controlled lab-based and environmental microcosms will be developed to carry out the molecular ecological interactions. DNA-based methodologies in combination with proteomic and confocal laser scanning microscopy will be used to assess the dynamics of interaction, biocontrol activity and expression of each other’s primary biocontrol genes. This research effort will result in new knowledge of the mode of the interaction between BCAs, BCAs and the pathogen, and BCAs and the plant. This will constitute the basis for the development of innovative biotechnological applications.";249890,2;249890,2;FP7-PEOPLE-2011-IEF;/MC-IEF;TECHNISCHE UNIVERSITAET GRAZ;AT;;;/SCI;1;0;0;1;0;0 90219;227985;TRAVERSE;ONG;FP7-IDEAS-ERC;ERC-AG-ID1;FP7;Transcending Reality Activating Virtual Environment Responses through Sensory Enrichment;2009-04-01;2015-03-31;;"The goal of this project is to provide the means for transcending reality : to use virtual reality to transcend the self, whereby participants in an immersive virtual reality (IVR) may have the strong illusion of transforming their bodies, and therefore have experiences in VR that are not possible in physical reality. The goal is to use IVR for something that is genuinely new and uniquely possible within such systems, beyond the normal representational approach to VR which attempts mainly to faithfully simulate reality. The research is based on three fundamental ideas: (a) that our body image is highly malleable, and that virtual reality can be used to transform it; (b) that the brain has sufficient plasticity to remap tactile sensations, so that a sensation felt on one part of the body can be associated with an event on another part of the body and that therefore this can be used in VR in order to endow virtual experiences with physicality; (c) that the brain can be fooled into inferring that something perceived in VR is really happening (even though the person knows for sure that it is not) and that there are techniques that can be employed in VR to enhance the probability that this occurs. Hence the research is interdisciplinary, a novel combination of neuroscience and computer science, with the likelihood of benefits to both. The work is organised into three major Streams corresponding to (a)-(c), where specific hypotheses are derived from the general idea and tested empirically. Each set of experiments requires an engineering solution. A fourth Stream of work will be for integration creating scenarios for the testing of the general hypotheses implied by (a)-(c). The main application will be in social virtual environments, where a human participant interacts with virtual characters, or a mixture of virtual characters and other online people represented in the VR. Applications would be in the fields of therapy, physical rehabilitation and entertainment.";2409768;2409768;ERC-2008-AdG;/ERC-AG;UNIVERSITAT DE BARCELONA;ES;;;/SCI;1;0;0;1;0;0 103446;299789;MeViSP;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IIF;FP7;Genetic, biochemical and cell biological mechanisms of virus silencing in plants;2013-03-01;2015-02-28;;"RNA silencing pathways exist in most eukaryotes and regulate endogenes to integrate development and environmental responses, and protect organisms against foreign nucleic acids including viruses and transposons. In plants, small interfering RNA (siRNA) and microRNA (miRNA) duplexes of 21-24bp are produced from double-stranded RNA (dsRNA) precursors by Dicer-like RNaseIII enzymes (DCL1-4). Selected si/miRNA strands are then loaded into Argonaute proteins (AGO1-10), which guide an RNA-induced silencing complex (RISC) to mediate sequence-specific post-transcriptional gene silencing (PTGS) at the RNA level, and transcriptional gene silencing (TGS) at the chromatin level. Plant resistance to RNA viruses requires these same components, notably DCL2 and 4 for production of viral-derived siRNAs, AGO1 and 2 to guide viral-targeted RISCs, and an RNA-dependent RNA polymerase (RDR6) and the RNA binding protein SGS3 for amplification of viral dsRNA. While the central role of these factors is well-established, the molecular mode of action that enables these proteins to restrict viral replication is unknown; in fact, the field of RNA silencing is actively studying the extent to which endogenous mRNAs are silenced by AGO-mediated cleavage (“slicing”) or by translational repression (TR) coupled to mRNA decay. In addition, many questions regarding the cell biological and genetic basis for viral silencing have yet to be addressed in a satisfactory manner. This proposal outlines a series of interdisciplinary and mutually-reinforcing experiments to 1) test the mode of action of viral silencing, specifically the relative contributions of slicing and TR during resistance; 2) discover cell biological aspects of viral silencing, particularly where in cells RNA silencing components target viral RNA, and which forms of viral RNA are targeted; and 3) conduct the first large-scale forward genetic screen designed exclusively to reveal components required for viral silencing and its suppression.";184709,4;184709,4;FP7-PEOPLE-2011-IIF;/MC-IIF;EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH;CH;;;/SCI;1;0;0;1;0;0 106404;318909;DIGIT-M-ED;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IRSES;FP7;Global Perspectives on Learning and Development with Digital Video-Editing Media: A Qualitative Inquiry in Everyday Lives of Marginalized Young People;2012-06-26;2014-06-25;;'The exchange concerns the social, cultural, media-analytical and educational-psychological dimensions of digital media practices with a focus on the devices that are used for capturing, editing and circulating video data. DIGIT-M-ED applies inter-disciplinary perspectives and knowledge to analyse how the use of digital technologies is shaped by and shapes today’s global youth. Solid research synergies between German and Indian traditions of anthropological and sociological youth research, British scholarship in media analysis, Greek and Brazilian educational and youth research and Russian learning theories will be constructed more fully and creatively. Moreover, the methodological contribution of the project is very important. DIGIT-M-ED aims to develop an innovative methodology for the interdisciplinary and comparative/cross-cultural study of emerging digital media and technological practices and constellations with special attention to the voices and perspectives of the young people involved in the research. Existing theoretical and methodological tools from 1) post-Vygotskian psychology and learning theory 2) multimodal analysis and 3) anthropological theoretical and research traditions will be tested and further developed. A small-scale inquiry with young people in the age of 16-21 years who live in marginalized urban milieus in Athens, New Delhi and S?o Paulo is planed with the aim of designing large-scale research in the near future. Further activities such as workshops, collaborative teaching and joint publications and presentations will expand and intensify existing research partnerships. DIGIT-M-ED will thus facilitate the development of a productive and sustainable international research network that will investigate how digital media and technologies transform the everyday lives and affect the development of young people in North and South Europe, Brazil, Russia and India in the years to come.';222100;222100;FP7-PEOPLE-2012-IRSES;/MC-IRSES;PANEPISTIMIO KRITIS;EL;"INSTITUTE OF EDUCATION, UNIVERSITY OF LONDON;FREIE UNIVERSITAET BERLIN";"UK;DE";/SCI;1;0;0;1;0;0 100278;272996;GLOBLOC BIOBANKS;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-IOF;FP7;"Negotiating local and global requirements in biomedical research; the case of biobanking";2012-03-01;2015-02-28;;"Biobanks are large scale storages of human tissue and data that are attributed a vital role as infrastructure for large scale genetic research. Biobanks can be used optimally if exchange of materials and data would be possible; however, many biobanks are established with local interests in mind and are therefore difficult to coordinate with each other. In this project I will explore how the tension between global and local affects 1. the input of materials and data, 2. the output of research results, diagnostics, etc. and 3. the governance of biobanks through legislation, guidelines, etc. in biobanks in the US, India, Singapore and Europe. I will do this by performing an in-depth qualitative study of teh various projects, using analytical resources from the interdisciplinary field of science and technology studies (STS). Performing such an analysis will contribute to insights into the effects of globalisation on medical reseach and generate new options for policy making in this area. In this project, I will collaborate with two of the foremost scholars in STS. I will spend my outgoing phase with Professor Sheila Jasanoff at Harvard University and my return phase with Professor Wiebe Bijker at Maastricht Unviersity. Researchers at both institutiones have extensive experience in social studies of biomedical research and have adopted globalisation as an important research team. Working at these two institutions will therefore allow me to strengthen my profile in cross-national comparative research on science, technology and society and support me in becoming one of the leading figures in the emerging area of studies of globalisation in STS. Additionally, my fellowship will strengthen the ties between two outstanding research programs in STS and will contribute to prolonged collaboration in the future. Finally, my project can contribute to improved policy making on health and research in the European Union.";228529,6;228529,6;FP7-PEOPLE-2010-IOF;/MC-IOF;UNIVERSITEIT MAASTRICHT;NL;;;"/EMP;/SOC;/COO";1;0;0;1;0;0 108490;328977;X-PHI AESTHETICS;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IIF;FP7;Experimental Philosophical Aesthetics and Human Nature;2014-01-15;2016-01-14;;"The project is a work of philosophical psychology that investigates aesthetic processes in the context of human nature. Our basic hypothesis is that aesthetics is fundamentally intertwined with morality and language. What sets this project apart from previous philosophical efforts in this realm is the project’s central commitment to empirical investigations and its robust interdisciplinarity. We will tackle classic problems that connect aesthetics to morality and language with both traditional philosophical tools and empirical methods from the cognitive sciences. Hence, in addition to providing a deepened understanding of human nature, the project will also transfer a new philosophical methodology into Europe. Our project will be the first to show how and why the philosophical application of empirical methods will illuminate the non-perceptual aspects of our aesthetic engagement with the world. By focusing on the interactions between aesthetic processes and the capacities that underlie morality and communication, we aim to uncover relationships between aesthetic value, moral value, and the human mind that may be too subtle to detect through the use of traditional philosophical tools alone. The Fellow, Dr. Shen-yi (Sam) Liao, is ideally suited to drive this project to success because he has a unique background that includes both expertise in philosophical aesthetics and experience in empirical methodology. The Host, Dr. Aaron Meskin of University of Leeds, heads up the world-leading Centre of Aesthetics, which possesses a special strength in approaching philosophical aesthetics from a naturalistic perspective. Through knowledge transfer activities such as a summer school and workshops, the fellow will transfer his unique knowledge and skills to European academics. Through outreach activities such as a podcast and collaborations with museums, the project will enrich European citizens' intellectual and cultural lives.";231283,2;231283,2;FP7-PEOPLE-2012-IIF;/MC-IIF;UNIVERSITY OF LEEDS;UK;;;/SCI;1;0;0;1;0;0 102583;301840;BONAFIDE;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IEF;FP7;Banking on new antimicrobials: translational fidelity impairment;2012-03-01;2014-02-28;;"'Infectious diseases represent an incessant threat for the human population worldwide. The rapid evolution and flexible metabolism of bacterial pathogens have caused a staggering global rise in antibiotic resistance. Our project aims to contribute to the pressing need for discovery of new antibacterial targets. The project will combine the applicant`s expertise in molecular biology and biochemistry, together with the competence of the host lab in infection biology, bioinformatics and high-through-put methods, to evaluate potential targets for new antimicrobials development. Protein biosynthesis accuracy is an integral part of the living cell health. Errors during translation of genetic information into proteins may lead to nonfunctional and toxic product formation. We propose to evaluate frameshifting, the most severe type of translational inaccuracy, in a systematic and quantitative fashion as means to defeat bacterial pathogens. Our preliminary data show that it is possible to invoke avirulence by targeting frameshifting control in the pathogen Salmonella. To reach our objective, we have developed a fluorescence-based tool to monitor translational mistakes in vitro and in vivo using flow cytometry. We will collaborate with core facilities to use proteomics and gene expression profiling to decipher downstream effects of mistranslation. The results will be validated in the murine model of typhoid fever. These data will be used to create an in silico model for Salmonella that, fed by genomic information of other bacterial pathogens, could predict potential broad-spectrum drug targets. The academic benefit of the project involves promotion of an interdisciplinary approach and mutual exchange of state-of-the-art methodology between the host lab and the researcher. The researcher will enhance her individual competences as an independent investigator, master cutting-edge techniques, and strengthen her tutor skills within proposed out-reach activities.'";192622,2;192622,2;FP7-PEOPLE-2011-IEF;/MC-IEF;UNIVERSITAT BASEL;CH;;;/SCI;1;0;0;1;0;0 106510;316723;PERFUME;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-ITN;FP7;Peroxisomes: key to cell performance and health;2013-01-01;2016-12-31;;"The PERFUME (PERoxisome Formation, Function, MEtabolism) program is an interdisciplinary and intersectoral ITN providing state-of-the-art research training at the interface of medicine, plant and fungal biology. The PERFUME S&T specifically aims at unraveling the principles of peroxisome biology. Peroxisomes have been discovered relatively recently (in 1954). Consequently, the level of understanding of their biology is relatively weak compared to the knowledge of other organelles. Despite their modest appearance, they are crucially important for cell vitality. Peroxisomes ubiquitously occur in eukaryotes, display an unprecedented versatility of functions and are essential in man. Recent findings indicate that improper functioning of peroxisomes contributes to ageing and age-related diseases. However, there are still major gaps in our current knowledge of peroxisome biology. PERFUME aims to fill these gaps by focusing on i) the identification of novel peroxisome functions, ii) in-depth understanding of the compartmentalization of functions in peroxisomes and iii) unraveling the principles of peroxisome proliferation. Enhancing knowledge on these three themes is relevant for medicine, agriculture and biotechnology and demands directed analyses, which require the combined expertise from different disciplines and sectors that cut across historically separated fields. PERFUME brings together such a team comprising of top scientists from the fields of cell biology, biochemistry, genomics, proteomics, metabolomics, mathematical modeling, bioinformatics and protein structure analysis. Together, PERFUME shows maximal complementarity and synergy to warrant optimal training facilities for the participating students.";3911064,03;3911064,03;FP7-PEOPLE-2012-ITN;/MC-ITN;RIJKSUNIVERSITEIT GRONINGEN;NL;"LIFEGLIMMER GMBH;THE UNIVERSITY OF EXETER;UNIVERSIDAD PABLO DE OLAVIDE;EUROPEAN MOLECULAR BIOLOGY LABORATORY;Evitraproteoma AB;ACADEMISCH ZIEKENHUIS GRONINGEN;RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG;RUHR-UNIVERSITAET BOCHUM;UNIVERSITETET I STAVANGER;Academisch Medisch Centrum bij de Universiteit van Amsterdam;METABOLOMIC DISCOVERIES GMBH";"DE;UK;ES;SE;NL;NO";/LIF;1;0;0;1;0;0 101583;289404;ACT;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-ITN;FP7;Action research: Improving understanding and methodologies in early development;2012-01-01;2015-12-31;;The ACT Initial Training Network aims to establish a leading European training network devoted to investigating the interplay between action and cognition using a developmental approach. The ACT network represents a collective of scientific and industrial groups at the cutting edge of research in the fields of social development, developmental psychology, cognitive science, developmental neuropsychology, and computational science. The network will train PhD students and produce new technology to answer critical issues in our understanding of human development. A core assumption of the network is that development of perception, motivation, and cognition is grounded in, and develops through, our own actions (von Hofsten, 2004). We learn about our physical environment by actively engaging with the world. As we develop new action capabilities, new elements of the environment become salient to us. This process is especially prominent early in infancy when action capacities and an understanding of the world develop. The nature of developmental research demands a multi-method approach. As a result, we propose to rigorously train ESRs such that they obtain two or more techniques required to study the relationship between brain and behaviour in early social development. We will conduct research and training within and between academic and industry partners on the role of attention in action, prospective control, social interactions, and semantics in action. We will improve technologies so that movement analysis is possible with infants. We will also develop an eye tracking system that links to EEG and we will create tools that are designed specifically for infant EEG data. In addition to these major breakthroughs in our knowledge, we will provide a structured training programme for Early Stage Researchers that capitalizes on cross-European strengths that will produce cutting edge leaders within the field in a unique and timely interdisciplinary training programme.;3026277,61;3026277,61;FP7-PEOPLE-2011-ITN;/MC-ITN;LANCASTER UNIVERSITY;UK;"STICHTING KATHOLIEKE UNIVERSITEIT;TOBII TECHNOLOGY;UNIVERSITY OF DURHAM;BRAIN PRODUCTS GMBH SOFT- UND HARDWARE FUER NEUROPHYSIOLOGISCHE FORSCHUNGSANWENDUNGEN;QUALISYS AB;UPPSALA UNIVERSITET;BIRKBECK COLLEGE - UNIVERSITY OF LONDON";"NL;SE;UK;DE";"/LIF;/SCI";1;0;0;1;0;0 108566;313195;SECILE;ONG;FP7-SECURITY;SEC-2012.6.5-1;FP7;"""Securing Europe through Counter-Terrorism—Impact, Legitimacy and Effectiveness""";2013-05-01;2014-10-31;http://secile.eu/;"'This project aims to create an empirically-informed view of the legitimacy and effectiveness of European security legislation, taking into account legal, societal, operational and democratic perspectives. It aims to produce an interdisciplinary and multi-stakeholder understanding of mechanisms for measuring the impact, legitimacy and effectiveness of legal measures, connecting theoretical and practical perspectives with a sound and operationally-informed analysis of these measures in practice. In this way it aims to identify the strengths, weaknesses, assumptions and dissonances across and between existing theoretical, institutional and operational perspectives. The strategic approach of the project is to create dynamic synergies between the legal, sociological and ethical disciplines, authorities and end users in order to generate a holistic understanding of the operation of European legal measures from the perspective of impact, legitimacy and effectiveness. We will do this through the use of both inter-disciplinary desk research and, vitally, concentrated engagement with end user groups in in-depth case studies in order to bridge the gaps in understanding between theoretical and legal perspectives, on the one hand, and operational and practical needs on the other. This project will enable the generation of better mechanisms to assess the legitimacy of legal instruments, for Security, in the context of both efficacy and societal acceptability providing both European and national authorities and implementing bodies with an operable perspective to be applied in designing, implementing, transposing and assessing such security measures. This will improve the overall effectiveness and legitimacy of European security measures and their implementation within and across member states, with a view to limiting such measures to legitimate and proportionate intrusion in citizens’ liberties.'";811000,8;703098,25;FP7-SEC-2012-1;/CSA-CA;UNIVERSITY OF DURHAM;UK;"ELIZABETH ANN SINGLETON;CENTRE FOR IRISH AND EUROPEAN SECURITY LIMITED;LATVIJAS REPUBLIKA;CORK INSTITUTE OF TECHNOLOGY;INSTITUTT FOR FREDSFORSKNING STIFTELSE;KING'S COLLEGE LONDON";"UK;IE;LV;NO";/SCI;1;0;0;1;0;0 107338;329404;SRSR;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IIF;FP7;Deciphering small RNA mechanisms during sexual reproduction in Arabidopsis;2013-04-01;2015-07-29;;"Sexual reproduction is a key moment in many organisms’ life cycle that ensures the proper inheritance of traits and also allows adaptation. In both plants and metazoans, reproduction entails the complex coordination of gene expression between the different tissues involved. For example, intricate modifications of epigenetic landscapes occur during and around fertilzation to ensure zygotic totipotency while maintaining genome integrity. In recent years, key connections have been established between silencing small (s)RNA and reproduction with the discovery of piwi-associated small RNAs (piRNAs) in Drosophila. In the model plant Arabidopsis, a clear link exists between silencing sRNAs and the chromatin via de novo DNA methylation and Histone tail modifications, in a process referred to as RdDM. However, almost nothing is known about the involvement of sRNAs in the reproductive process. This project aims at filling this gap by studying sRNA-mediated mechanisms in tissues before and after fertilisation, i.e. in the plant germline and in the zygote. This proposal outlines a series of interdisciplinary and mutually reinforcing experiments to 1) Characterize the silencing machinery available during sexual reproduction in Arabidopsis; 2) Establish an unbiased developmental map of reproduction-associated sRNA; and 3) study the possible movement of sRNAs between and toward reproductive organs. The results are expected to shed a completely new light on plant reproduction and, more generally, might unravel novel sRNA-based regulations. The proposed project also has profound implications in agriculture as it may elucidate aspects of the poorly understood mechanisms underpinning hybrid vigour as well as intra- and inter-species compatibility. Finally, knowledge on cell biology, imaging and Arabidopsis reproduction biology implemented during the proposed project will contribute to European excellence and competitiveness in the field.";184709,4;184709,4;FP7-PEOPLE-2012-IIF;/MC-IIF;EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH;CH;;;/SCI;1;0;0;1;0;0 107495;310235;SUMORICE;ONG;FP7-IDEAS-ERC;ERC-SG-LS9;FP7;SUMOrice: Exploiting an emerging protein modification system, SUMOylation to boost rice yield during drought and salt stress;2013-04-01;2019-03-31;;"'To feed 9 billion people by 2050 is an unprecedented challenge. Rice is the food source for the majority of the world's population but also a model for cereals. Drought and related high salinity during essential periods of plant growth affects nearly all crops including the major cereals such as rice causing drastic yield losses. A major goal of plant biology is to develop crop cultivars that are 'drought and salt resistant', defined as those that have higher yields than standard cultivars under these environmental stresses. However plant responses to drought and salinity are overlapping and complex involving many physiological pathways controlled by cascades of molecular networks. This makes engineering drought and salt resistance in crops possible but very challenging unless we identify molecular mechanisms (‘Master’ co-ordinators) that can influence multiple signalling networks to produce an integrated stress response. Crop improvement programmes that target these ‘Master’ co-ordinators will have the greatest potential for yield increase. We have discovered that SUMOylation, an emerging protein modification mechanism can be recruited to co-ordinate multiple molecular response pathways to dramatically improve plant growth on high salinity and during drought stress. This groundbreaking and exclusive discovery ideally places us to exploit this finding to generate stress resistant crops. SUMOrice is a pioneering interdisciplinary proposal that uses an innovative approach to produce novel alleles of genes regulating multiple stress signaling cascades. To achieve this we will use an unconventional blend of 2 platform technologies (SUMO proteomics, ecoTILLING) to produce drought and high salt resistant rice. SUMOrice is 5-year project that brings together a team of 4 scientists (PI (50%), postdoc, technician, senior scientist in proteomics) with complementary skills in molecular biology, biophysics, biochemistry, cereal genetics and stress biology to achieve these aims.'";1487965;1487965;ERC-2012-StG_20111109;/ERC-SG;UNIVERSITY OF DURHAM;UK;;;"/ABI;/BIO;/LIF;/MED;/MBI";1;0;0;1;0;0 108371;328215;ESENCYA;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IOF;FP7;Environmental sensory perception in cyanobacterial biofilms: understanding biodeterioration of outdoor stone materials in a changing environment;2013-08-01;2016-07-31;;"Many of the world’s most precious artworks are made of stone and their irreversible disappearing due to biological attack is a worldwide concern. Cyanobacteria colonize outdoor surfaces and develop biofilms, which, in turn, causes aesthetic, chemical and physical decay. The fragile character of the stone heritage material is further exacerbated by the unpredictable nature of environmental changes impacts, posing challenges for conservation management. Although there have been EU projects and scientific papers on cyanobacteria, the role and behavior of these microorganisms within the biofilm matrix and their complex interactions with the external environment is still unknown. ESENCYA provides an innovative, interdisciplinary and multidisciplinary research to investigate perception of environmental changing in cyanobacteria within the biofilm matrix for sorting out time-spatial relationships and to elucidate microorganism-matrix, inter-organism, biofilm-atmosphere and biofilm-stone interactions. The project spans sophisticated microscopic techniques, biofilm matrix and gene expression analysis, damage assessment and data modeling techniques in world leading research institutions in microbial biofilm in USA and in cultural heritage microbiology in Italy. The research will be approached from two complementary angles: i) Lab-scale study to examine the sensory machinery of cyanobacterial biofilms by analyzing the cell’s capacity to sense different chemical and physical properties of the biofilm matrix, to integrate the incoming signals and to respond to them, triggering specific biodecay activities; ii) real heritage case studies to investigate the ecological landscape of cyanobacteria within subaerial biofilms. The outcomes will generate valuable new knowledge to model and predict surface biodeterioration in the face of environmental changes. This project represents an opportunity for Europe to keep its world leadership in research and conservation of cultural heritage.";261627,6;261627,6;FP7-PEOPLE-2012-IOF;/MC-IOF;UNIVERSITA DEGLI STUDI DI MILANO;IT;;;/LIF;1;0;0;1;0;0 106315;300805;Embodied Attachment;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IEF;FP7;Behavioural and physiological markers of Parental Embodied Mentalising: Cultural, gender, and attachment factors;2012-11-01;2014-10-31;;"parental mentalising, the parent’s capacity to regard the child as a psychological agent (Sharp & Fonagy, 2008), is an important factor predicting attachment security (e.g., Slade et al., 2004).Thus far, all formulations of parental mentalising conceptualise and measure it as verbal, explicit, and reflective capacity (e.g. Meins, 1999; Slade, 2002).Despite their empirical contribution, these approaches are limited in their ability to illuminate the process through which parental mental capacities actually shape the child’s representation of their relationship in terms of attachment security. Shai and Belsky (2011a, b) recently introduced the construct and measure of parental embodied mentalising (PEM), an implicit, body-based, and interactive approach to parental mentalising. A study of 150 mothers interacting with their 6-months-old infants found that the parent’s PEM profile not only predicted the child’s attachment at 15 months over and above established maternal sensitivity measures, but that once PEM variables were accounted for maternal sensitivity was no longer predicted attachment (Shai & Belsky, submitted). However exciting and promising these findings are, they are preliminary and call for further investigation. Using multiple cutting-edge methods, including psychophysiological, behavioural, and self-reports this research scrutinizes four questions: 1) Can PEM be cross-culturally validated such that maternal PEM in an Israeli sample will predict attachment security as in the American sample? 2) What are the behavioural similarities and differences between paternal and maternal PEM? 3) What are the links between behavioural and psychophysiological measures of PEM? 4) How does adult attachment associate with PEM and with child attachment security? This research makes a new contribution to the study of embodiment from an interdisciplinary whole-body movement perspective and will lead to the development of novel therapeutic interventions for parents and infant";180342;180342;FP7-PEOPLE-2011-IEF;/MC-IEF;INTERDISCIPLINARY CENTER (IDC) HERZLIYA;IL;;;/SCI;1;0;0;1;0;0 101985;272021;MODALAN;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-IEF;FP7;Model Theory and Algebraic Analysis;2012-12-01;2014-11-30;;"'The researcher Dr. Luca Prelli will carry out the interdisciplinary project 'MODALAN': Model Theory and Algebraic Analysis at the University of Lisbon, Portugal. At the host institution there is a scientific expertise that suits the researcher's needs excellently since it houses young and active researchers in model theory plus it is home to some of the best specialists in algebraic analysis. A contact between these two fields of mathematics is very rare and, at the present point of his career, for the applicant it would be essential to acquire new cutting-edge skills. Within a period of 24 months, the aim of this research project is to develop the applicant's knowledge in algebraic analysis and geometry and acquire new skills in two different subjects: the algebraic study of PDE on one side and the analytical model theory on the other. The nature of this proposal is strongly multidisciplinary since it involves different branches of mathematics as algebra, analysis, geometry and logic. In particular, concerning 1), we would like to extend classical methods of algebraic analysis and apply these new techniques to approach Cauchy problems with growth conditions. Concerning 2), we intend to contribute to the development of the study of o- minimal sheaf cohomology in order to obtain a general solution of the Pillay conjecture. The applicant has already acquired professional maturity, independence and international visibility. He spent various research periods abroad, established collaborations and made scientific publications with other foreign researchers. The action can make a significant contribution to the applicant's professional maturity. He will be integrated into a high level foreign university structure and professionally recognized in another national context while having the possibility of expanding his knowledge and research qualities. In the long term perspective, this will support the applicant in furthering his academic career at an international level.'";152449,6;152449,6;FP7-PEOPLE-2010-IEF;/MC-IEF;FUNDACAO DA FACULDADE DE CIENCIAS DA UNIVERSIDADE DE LISBOA FP;PT;;;"/EMP;/EDU;/NET";1;0;0;1;0;0 192997;335880;SPECFIN;ONG;FP7-IDEAS-ERC;ERC-SG-SH4;FP7;Spectral Fingerprints of Neuronal Interactions;2015-01-01;2019-12-31;;"'How does cognition result from complex neuronal interactions within and between brain regions? Substantial progress has been made understanding the functional properties of individual neurons, but we lack understanding of how they work together. Neuronal oscillations are ubiquitous in the brain. The frequencies of these oscillations reflect the biophysical properties of underlying circuit interactions. Thus, frequency-specific oscillations may serve as ‘spectral fingerprints’ of specific circuit interactions. However so far, the circuit interactions underlying cortical oscillations are largely unknown. The key objective of my proposal is to establish this ‘spectral fingerprint’ framework for the human brain, by identifying elementary circuit interactions underlying non-invasive M/EEG oscillations. We will employ a novel interdisciplinary approach that tightly links human and monkey electrophysiology. First, we will perform directly comparable EEG (and MEG) recordings in humans and monkeys using identical behavioural tasks to identify consistent local and large-scale oscillations in both species. Second, we will characterize the neuronal circuit interactions underlying these non-invasive oscillations in monkeys using simultaneous EEG and intra-cortical recordings as well as electrical and pharmacological manipulations. If successful, this work will constitute a paradigm shift in cognitive neuroscience by linking two largely disconnected disciplines: human and monkey electrophysiology. Identifying spectral fingerprints of elementary circuit interactions will establish a powerful new framework to understand cognitive processes in terms of mechanistic, network-level building blocks.'";1494480;1494480;ERC-2013-StG;/ERC-SG;EBERHARD KARLS UNIVERSITAET TUEBINGEN;DE;;;/SOC;1;0;0;1;0;0 96015;253654;CGPESA;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IEF;FP7;COMMUNITIES, GOVERNANCE AND PAYMENT FOR ECOSYSTEM SERVICES IN AMAZONIA;2010-09-01;2012-08-31;;This proposal is for a study of the local governance implications of Payments for Ecosystem Services (PES), especially hydrological services, in the Amazon basin. Such payments, which may also take the form of development projects, compensate local actors for the opportunity costs of maintaining their rainforest environment through sustainable practices - in the case of indigenous peoples in Amazonia, this implies maintaining traditional livelihoods. As PES are increasingly accepted as a solution for REDD (Reducing Emissions from Deforestation and Degradation) in the context of international negotiations over measures to reduce the harmful effects of climate change, there is an increasing trend for such payments to be made on an international scale. PES is therefore quickly becoming a significant international development model. However, for it to be effective in reducing deforestation and therefore in mitigating climate change, and for it effectively to reduce poverty and improve wellbeing, it is vital that problems of local governance in the remote rainforest regions concerned by PES be well understood. However, no previous primary research has focused on the sociopolitical and governance implications of REDD projects. The fellow, a social anthropologist, will collaborate with an expert in environmental governance to gather original data on PES projects in Amazonia and develop a theoretical framework for studying the problems of environmental governance that they raise. He will produce three articles and a monograph, organise an international conference, and issue policy recommendations based on the research results. In addition to research training, he will gain interdisciplinary skills (training in political ecology) and organisational, collaborative and intersectoral experience (by collaborating with international development organisations), which will prepare him for a leading position at the interface of academia and international development practice.;180970,8;180970,8;FP7-PEOPLE-2009-IEF;/MC-IEF;FONDATION POUR L INSTITUT DE HAUTES ETUDES INTERNATIONALES ET DU DEVELOPPEMENT;CH;INSTITUT DE HAUTES ETUDES INTERNATIONALES ET DU DEVELOPPEMENT;CH;"/SCI;/EDU;/ITT";1;0;0;1;0;0 105081;321725;Sym's Gene;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-CIG;FP7;Understanding Symbiotic Diversity: aCandidate Gene approach;2013-06-01;2017-05-31;;"Interaction between plant root and arbuscular mycorrhiza (AM) is a crucial symbiosis in nature and present in almost all crops. In addressing plant responses to stress, this proposal shifts the focus from the host to the symbiotic unit. By recognizing symbiosis to be a major player in evolution, the interplay is valued between the adaptive regulation of host and symbionts metabolisms. Using wild carrots, their AM community and the alternatieve oxidase (AOX) candidate gene, the researcher will address the prediction that AOX gene polymorphisms are drivers in interlinked plant and AM fungi evolution. This project studies - for the first time - the interaction between plant and AM in natural ecosystems using a crucial candidate marker, followed by experiments exploring driving effects of evolution. The research will lead to better understanding of evolutionary processes that shape the composition of the symbiosis and of the benefit of diversity to crop productivity. The approach is interdisciplinary: physiology, ecology and evolutionary genetic methodologies. There is high commercial interest in appropriate breeding strategies based on efficient genotype-mycorrhiza as they can promote, a.o., a more sustainable use of phosphorus in crops and minimize associated biodiversity losses, and mitigate the impacts of global climate change on agricultural and native plant communities. A similar proposal was previously submitted in 2011-CIG which achieved overall high scores. The present proposal addresses the referees’ comments, which mainly concerned better explanation of the methodologies and their feasibility. The researcher’s profile closely matches the project needs, and her independent thinking and entrepreneurship, together with the high academic profile of the host Marie-Curie chair, provide a strong foundation for successful implementation of this project and long-term integration of the researcher.";100000;100000;FP7-PEOPLE-2012-CIG;/MC-CIG;UNIVERSIDADE DE EVORA;PT;;;/LIF;1;0;0;1;0;0 108780;328197;DEEPCO;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IOF;FP7;Connectivity of deep-sea ecosystems under increasing human stressors: an integrative approach addressing vulnerability and ecological risk assessment;;;;"Understanding the least studied biome on Earth, the deep sea, is a major 21st century challenge. The deep sea supports an important reserve of biodiversity as well as valued biological and mineral resources, which are increasingly being exploited. Knowledge on the early life-history patterns and, in particular population connectivity, of most deep-sea organisms is lacking or very limited, but is essential to understand the maintenance of populations and their resilience to natural and anthropogenic change. I propose to develop an interdisciplinary project that will involve biologists, oceanographers, modellers and end-users (government, industry), to determine population connectivity in New Zealand and Mediterranean deep-sea habitats, and use this information, together with available early-life history, biodiversity and trophic data, in ecological risk assessment models to assess the vulnerability of exploited, or soon to be exploited, deep-sea systems. The end goal is to provide scientific information that will enable the evaluation of management options to reduce or mitigate fishing and mining impacts on benthic and fishery production systems. The project is structured in 3 interconnected objectives: 1) compile early life-history data of selected species; 2) determine population connectivity by developing biophysical models of larval transport; 3) assess vulnerability of the studied communities through the application of risk assessment models. During the outgoing phase in NIWA (New Zealand), I will provide my expertise on early-life histories and I will learn novel modelling tools for the investigation of larval transport and risk assessment. The new skills acquired in NIWA will be applied to available Mediterranean data from the return host group in ICM-CSIC (Spain), where these methods have never been applied before, addressing a major issue of the European Research Area in relation to management of exploited deep-sea systems.";330380,5;330380,5;FP7-PEOPLE-2012-IOF;/MC-IOF;AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS;ES;;;/LIF;1;0;0;1;0;0 107870;333374;BITRENEGOTIATION;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-CIG;FP7;The Renegotiation of International Agreements: The Case of Bilateral Investment Treaties;2013-04-01;2017-03-31;;Given that their main function is to forge durable commitments, it is notable that many international treaties have changed over time through the increasingly common practice of renegotiation. While some agreements have remained intact after their initial conclusion, others are amended, updated, or replaced. Why are some international agreements renegotiated while others remain stable? Despite growing interest in agreement flexibility and renegotiation provisions as an institutional design outcome, extant research has not addressed the question of renegotiation itself with much depth or rigor. This interdisciplinary project will offer a systematic analysis of treaty renegotiation by presenting theoretical propositions and testing them in the context of bilateral investment treaties (BITs). With over 150 BITs having been renegotiated since the early 1990s, this set of treaties provides a nice laboratory for studying the phenomenon. Building on contract theory and the rational design literature, I intend to develop a set of testable hypotheses on renegotiation based on three mechanisms: overcoming uncertainty through learning, exogenous changes in circumstances, and shifts in the balance of bargaining power between the parties to the treaty. This framework will be evaluated with a combination of qualitative and quantitative approaches that include in-depth interviews of government officials and other individuals engaged in BIT-related policies, content analysis of investment treaties, and a large-N regression analysis. This aspect of the project involves the completion of an original data base of all renegotiated BITs and their content, which is currently not available.;100000;100000;FP7-PEOPLE-2012-CIG;/MC-CIG;THE HEBREW UNIVERSITY OF JERUSALEM;IL;;;/LIF;1;0;0;1;0;0 107433;327424;NINA;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IEF;FP7;Norms in Action: Designing and Comparing Regulatory Mechanisms for Multi-Agent Systems;2013-04-01;2015-03-31;;"'In multi-agent systems, where human and software entities freely interact, the goals of the individual components are often different and at times utterly incompatible, hindering the possibility of reaching desirable and efficient outcomes. In such situations there is a strong need of an explicit regulation of individual behaviour, whose introduction has traditionally followed two alternative approaches, well-known in the economics literature: the 'spontaneous order' approach, which studies how norms result from endogenous agreements among rational individuals, and the 'mechanism design' approach, which studies how norms are exogenously designed in order to reach desirable properties. Before endorsing either approach, however, we need to confront ourselves with the unique structural features of each interaction: some may not be suitable for an endogenous agreement (e.g. absence of communication channels, too high computational requirements etc.) while others do not allow for an exogenous constraint (e.g. impossibility of verifying violations, impossibility of restraining behaviour etc.). The project 'Norms in Action: Designing and Comparing Regulatory Mechanisms for Multi-Agent Systems' (NINA) will study norm introduction in multi-agent systems within a unified formal framework and will deliver an automatic procedure to suggest the policy that suits best each interaction. The project will be grounded in Dr. Turrini’s PhD work, extending and generalizing his models of dependence relations in such systems, tailored to the expertise of the Department of Computing, Imperial College London, making use of their modelling and verification techniques, and highly interdisciplinary, analyzing game-theoretical models with computer science tools.'";221606,4;221606,4;FP7-PEOPLE-2012-IEF;/MC-IEF;IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE;UK;;;/SCI;1;0;0;1;0;0 98499;274083;MICMIT;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-IEF;FP7;Exploring the fundamental biology of microsporidian mitosomes;2011-05-02;2013-05-01;;'Microsporidia are tiny obligate intracellular parasites of other eukaryotes including patients with HIV/AIDS. Despite their importance, detailed knowledge of the biology of microsporidia is limited. Microsporidia were thought to lack mitochondria but the proposed host laboratory discovered, and have started to functionally characterise, highly reduced remnant mitochondria in these parasites, called mitosomes, which do not make ATP. Mitosomes are vital for parasite survival because they contain key components of the essential pathway for mitochondrial iron-sulphur cluster biosynthesis. However, from published and in- house genome data it appears that the transport proteins that support mitochondrial Fe-S protein biogenesis in model organisms, have been lost by the parasites. These data raise fundamental questions of how mitosomes function and import the substrates they need to produce Fe-S clusters or export the product(s) of this metabolism that (in model organisms) are needed for the biogenesis of essential cytosolic and nuclear Fe-S proteins. In the present proposal I will tackle these questions using a interdisciplinary program combining bioinformatics and organelle proteomics to identify putative mitosome proteins including transporters, molecular cell biology to functionally characterise these proteins, and detailed light and electron microscopy to confirm their localisation. The project will enhance my individual competence and potential for career development through experience of working in a leading UK laboratory with a track record of research training, international collaboration and scientific excellence.';200549,6;200549,6;FP7-PEOPLE-2010-IEF;/MC-IEF;UNIVERSITY OF NEWCASTLE UPON TYNE;UK;;;"/EMP;/EDU;/NET";1;0;0;1;0;0 108388;326781;EASTGRAB;CAN;FP7-PEOPLE;FP7-PEOPLE-2012-IEF;FP7;"""Understanding Land Grabbing in Eastern Europe and Central Asia: an Integrated Assessment of Impacts, Conflicts and Trade-offs""";;;;'The major aim of the EASTGRAB research project is to deepen the existing knowledge of the socio-economic and environmental aspects which characterize the process of agricultural land acquisitions due to commercial purposes, especially in marginalized and poor areas of the world. This process of land trade has been defined recently in the academic literature and in the media as “global land grabbing”. The convergence of global crises in food and energy, has driven a re-valuation of land resource. Transnational and national actors buy or lease large portion of land outside their country borders and all over the world to ensure food, energy and water security at home. The contemporary global land grab has recently become a key development issue. Due to the complexity of the topic, in terms of the large amount of aspects that have to be taken into account, as well as due to the novelty of the research field, in-depth analysis has become crucial in order to have deeper and meaningful debate around this issue. Further research is needed to collect information on land acquisition processes in countries where few studies have been (yet) undertaken, such as is the case of Eastern Europe, as well as Central Asia Region. The EASTGRAB project will further advance the scientific knowledge on this complex and emerging field of research from an interdisciplinary perspective in that region, and specifically in Ukraine, which due to the magnitude of foreign land acquisitions represents the most significant example of land grab in Eastern Europe. The research will integrate methods which belong to both social sciences, such as institutional and conflict analyses, and natural sciences, such as land use changes and environmental degradation due to natural resources’ exploitation. The results are expected to provide a better basis for rural development policies to achieve sustainability in rural areas of Eastern Europe in general and of the study area in particular.';175974,6;175974,6;FP7-PEOPLE-2012-IEF;/MC-IEF;ERASMUS UNIVERSITEIT ROTTERDAM;NL;;;/SCI;1;0;0;1;0;0 108107;329195;XLIM;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IIF;FP7;Well-defined Conjugated Block Copolymer Nanofibers and their Applications in Photovoltaic Devices;2013-04-08;2015-04-07;;'This proposal for a Marie Curie Fellowship focuses on the preparation of well-defined nanofibers from conjugated polymers and their use in photovoltaic devices. This project will be highly interdisciplinary and multidisciplinary, involving polymer synthesis, polymer self-assembly in the solution state, polymer crystallography, polymer physics, the physics of semiconducting materials, the fabrication and characterization of photovoltaic devices, and nanoscience. Therefore, this research is expected to have a substantial multidisciplinary impact ranging from polymer chemistry to polymer physics, to materials science, and to expand our knowledge of photovoltaic devices. To achieve the project goals it will be vital to combine the expertise of the applicant, Xiaoyu Li, on nanofibers and polymer-based device fabrication, with that of the host, Prof. Ian Manners, on polymer synthesis and crystallization-driven self-assembly of block copolymers in solution. Mr. Li is completing his Ph.D. in Canada and after working with Prof. Manners in the UK he aims to find a faculty position in China, his country of origin.';231283,2;231283,2;FP7-PEOPLE-2012-IIF;/MC-IIF;UNIVERSITY OF BRISTOL;UK;;;/SCI;1;0;0;1;0;0 104599;312097;FECUND;ONG;FP7-KBBE;KBBE.2012.1.3-04;FP7;Optimisation of early reproductive success in dairy cattle through the definition of new traits and improved reproductive biotechnology;2013-02-01;2017-01-31;;Good fertility is essential for the sustainability of livestock production. Of all livestock sectors, fertility of dairy cattle is raising the greatest cause for concern. Cow fertility has declined, particularly in Holstein cattle, from 80% pregnancy to first service 20 years ago to less than 40% today. Poor fertility is one of the main reasons for early culling, such that modern dairy cows complete fewer than 3 lactations, on average. The FECUND project will address the metabolic and genetic causes of low reproductive success of dairy cows in an interdisciplinary approach that will integrate in vivo and in vitro studies, biology, physiology, -omics technologies and bioinformatics. FECUND will focus on the early phases of reproduction from oocyte development to implantation of the conceptus. Starting from biological materials produced from high and low genetic merit cattle and from cows under energy stress of early lactation vs dry cows and heifers, FECUND will study, independently, the effects of genetics and metabolic stress on reproductive physiology to identify factors and early markers associated with high and low developmental potential, and with positive mother-conceptus interaction during the early stages of reproduction. These data will be mined to reveal physiological pathways and key candidate genes controlling variations of fertility. The biological knowledge created on early reproductive events in vivo will be validated in vitro, and extended to create further knowledge on the effects of the local environment on oocyte and embryo programming at the epigenetic level. Validated information will be used to improve herd management, gene assisted and genomic selection and assisted reproductive technologies, from in vitro ooctye maturation to optimised embryo culture. Information on biomarkers, indicator traits and improvements in assisted reproduction will be translated to applications that can be immediately implemented by SMEs.;3912649,3;2999393;FP7-KBBE-2012-6-singlestage;/CP-TP;Fondazione Parco Tecnologico Padano;IT;"INSTYTUT GENETYKI I HODOWLI ZWIERZAT POLSKIEJ AKADEMII NAUK;LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN;UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN;EUROPEAN FORUM OF FARM ANIMAL BREEDERS;AVANTEA srl;ALLICE;OSRODEK HODOWLI ZARODOWEJ OSIECINYSP ZOO;VETERINAERMEDIZINISCHE UNIVERSITAET WIEN;BAYERN GENETIK GMBH;INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE;NATIONAL CATTLE BREEDING CENTRE LIMITED;UNIVERSITA CATTOLICA DEL SACRO CUORE";"PL;DE;IE;NL;IT;FR;AT";/SCI;1;0;0;1;0;0 90164;230569;IPCWPPB;ONG;FP7-IDEAS-ERC;ERC-AG-ID1;FP7;Indigeneity in the Contemporary World: Performance, Politics and Belonging;2009-04-01;2014-11-30;;This project explores how indigeneity is expressed and understood in our complex, globalising world. It asks why indigeneity has accumulated immense symbolic and ideological capital in Western societies when indigenous cultures are among the most disenfranchised in modern times, often still struggling for social justice after centuries of colonisation. Specifically, I ask what indigeneity has come to mean in particular places and at key moments, and what kind of cultural, political, ethical and aesthetic issues are negotiated within its canvass. To address these questions, I will examine performance as a vital mode of cultural representation and a dynamic social practice. Performance is interpreted broadly to include not only the performing arts (theatre, film and dance) but also mixed-media work, site-based heritage projects, applied theatre in health education, Olympic pageantry, festival enactments, political protest and cultural displays within tourism ventures. The recent, rapid development of indigenous performance globally, its enthusiastic reception in national and international contexts, and its local significance and value will be studied in depth. I am especially interested in how evolving concepts of indigeneity may contribute to broader understanding of heritage, belonging, social cohesion and mobility in multicultural societies and how cultural values, knowledges and practices are transmitted, through performance, across place and time. The research will be thoroughly interdisciplinary, engaging with current scholarship in history, postcolonial studies, cultural geography, anthropology, environmental studies and performance theory. While the projected fieldwork focuses on regions settled during the great era of European expansionism, notably Australia, the Pacific Islands, the Americas and South Africa, the project is also centrally concerned with the transnational circulation of indigeneity as a highly marketable commodity, particularly in Europe.;2363323;2363323;ERC-2008-AdG;/ERC-AG;ROYAL HOLLOWAY AND BEDFORD NEW COLLEGE;UK;;;/SCI;1;0;0;1;0;0 108011;327440;PolyMoRe;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IEF;FP7;Polymeric ligands for molybdenum and rhenium clusters;2013-05-01;2015-04-30;;PolyMoRe will establish viable technology for a new class of tailored materials that will address pressing global demands in human healthcare and sustainable industrial development. Both sectors are priority areas in EU policy. Specifically PolyMoRe will bridge the gap currently preventing commercial exploitation of nano-sized metal clusters (MeCs) – unique materials with superb properties (photoluminescence, photoredox activity etc). To fully exploit the terrific potential of MeCs, methods will be developed to incorporate them into organic polymers to create novel materials with a plethora of applications that include bioimaging, cancer treatment, LEDs and solar cells. These materials will provide alternatives to expensive and environmentally harmful materials currently in use. Thus PolyMoRe will contribute significantly to the development of a “knowledge-based” economy that will create wealth and improve well-being in the EU. The knowledge that results from PolyMoRe will promote the EU as a leading centre for both academic and industrial research in healthcare and materials science. Another key objective of PolyMoRe is to provide a unique training for a highly skilled female researcher (returning to science after a short career break to start a family) with extant expertise in synthesis/manipulation of MeCs. PolyMoRe will significantly complement her existing skills in inorganic chemistry by training her in organic/polymer synthesis, modern analytical techniques and biotechnology, where the host institution, associate institutions and the company “Deliverics” have leading expertise. This will leave the Fellow uniquely qualified to pursue a high profile academic/industrial career as PI within the EU thus tackling the shortage of materials developers with genuine interdisciplinary skills. An additional legacy of PolyMoRe will be a new collaboration between the Fellow’s former research group in Russia, world-leaders in metal clusters, and Aston (UK).;231283,2;231283,2;FP7-PEOPLE-2012-IEF;/MC-IEF;ASTON UNIVERSITY;UK;;;/SCI;1;0;0;1;0;0 108725;329871;IRUSAT;CAN;FP7-PEOPLE;FP7-PEOPLE-2012-IOF;FP7;Improving Resilience of Urban Societies through Advanced Technologies;2014-07-01;2017-06-30;;Urban societies depend heavily on the proper functioning of infrastructure systems such as electric power, gas, potable water, and transportation networks. Normally invisible, this reliance becomes painfully evident when infrastructure systems fail during disasters. Moreover, because of the network properties of infrastructures, damage in one location can disrupt service in an extensive geographic area. The societal disruption caused by infrastructure failures is therefore disproportionately high in relation to actual physical damage. As a result of the project, new retrofitting strategies will be developed to improve the resilience of infrastructures to withstand natural hazards. The project aims to improve the resiliency of buildings, bridges, and communities in general through new advanced technologies such as base isolations, viscous dampers, etc. Base isolation systems that are able to control the shape of the floor response spectrum will be analyzed, in particular their behavior under vertical excitations. Attention will be given to infrastructural systems’ components and then it will be extended to performance of component assemblages (e.g., bridges, pipeline networks, etc.). The project will range from field work of specific lifeline damage in New Zealand, Japan and Italy after the earthquakes to laboratory simulations done in the laboratory of the University of California at Berkeley with scaled models and numerical analyses. Complexities of infrastructures, which include societal as well as technical issues will be addressed in the project. The project will try to answer through an interdisciplinary approach to the following questions: How, for instance, will the failure of one bridge affect businesses throughout the urban area that rely on the transportation system? How will the failure of one infrastructure system disrupt other infrastructure systems? How can repairs following a disaster be planned so they minimize social and economic losses?;351295,6;351295,6;FP7-PEOPLE-2012-IOF;/MC-IOF;POLITECNICO DI TORINO;IT;;;/LIF;1;0;0;1;0;0 102358;304023;FUSS;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-CIG;FP7;Flavor, Unification and Symmetries from Strings;2012-03-01;2015-08-31;;"The proposed research program takes place in the context of High Energy Physics and, more precisely, in the subfield known as string phenomenology. The main goal is to develop the potential of string theory to produce realistic models of Particle Physics and Cosmology, as well as to understand the interplay between Quantum Gravity and the phenomenology of such models. The proposed line of research will be focused in analyzing the string theory models known as type II/F-theory vacua, with special emphasis in models where the gauge interactions of nature are unified (Grand Unified Theory models). It is expected to achieve significant developments in this area via analyzing the physics of these models, and in particular by understanding the flavor problem of Particle Physics in this context. In this sense, it is expected that Quantum Gravity will impose a specific structure of flavor in the above models, via the existence of discrete symmetries. The research program aims to unveil such structure and to classify those characteristic signatures that could be detected in current accelerator experiments. The program does not only involve the formation of researchers into the field of string phenomenology and model building, but it also intends to profit form the interdisciplinary synergy that is currently emerging in the field of string phenomenology, involving physicists that are both more phenomenologically and more mathematically oriented.";87500;87500;FP7-PEOPLE-2011-CIG;/MC-CIG;AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS;ES;;;/SCI;1;0;0;1;0;0 108271;323711;M4;ONG;FP7-IDEAS-ERC;ERC-AG-SH4;FP7;Memory Mechanisms in Man and Machine;2013-05-01;2018-04-30;;"'The project aims to validate a set of 10 provocative claims. 1) Humans can recognize visual and auditory stimuli that they have not experienced for decades. 2) Recognition is possible without ever reactivating the memory trace in the intervening period. 3) During memorization, sensory memory strength increases roughly linearly with the number of exposures. 4) A few tens of presentations can be enough to form a memory that can last a lifetime. 5) Attention-related oscillatory brain activity helps store memories efficiently. 6) Storing such very long-term memories involves the creation of highly selective 'Grandmother Cells' that only fire if the original training stimulus is experienced again. 7) The neocortex contains large numbers of totally silent cells ('Neocortical Dark Matter') that constitute the long-term memory store. 8) Grandmother Cells can be produced using simple spiking neural network models including Spike-Time Dependent Plasticity (STDP) and competitive inhibitory lateral connections. 9) This selectivity only requires binary synaptic weights that are either 'on' or 'off', greatly simplifying the problem of maintaining the memory over long periods. 10) Artificial systems using memristor-like devices can implement the same principles, allowing the development of powerful new processing architectures that could replace conventional computing hardware. We will test these claims with a highly interdisciplinary approach involving psychology, neuroscience, computational modeling and hardware development. Novel experimental paradigms will study the formation and maintenance of very long term sensory memories. They will be combined with imaging techniques including fMRI imaging, EEG recording, and intracerebral recording from epileptic patients. In parallel, computer simulations using networks of spiking neurons with Spike-Time Dependent Plasticity will model the experimental results, and develop bio-inspired hardware that mimics the brains memory systems.'";2499480;2499480;ERC-2012-ADG_20120411;/ERC-AG;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FR;;;/MED;1;0;0;1;0;0 107088;327975;Nuclear Pore;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IEF;FP7;The nuclear pore permeability barrier – physical concepts and a biosynthetic approach to understand and exploit the unique selectivity of a natural macromolecular sieve;2013-03-01;2015-02-28;;"Nuclear pore complexes (NPCs) are the exclusive gate of entry/exit of macromolecules into and out of the nucleus of living cells. They exhibit a unique selectivity in transport, with respect to size and molecular species: very small molecules can diffuse efficiently through the pore, while larger objects are delayed/blocked unless they are bound to specialized proteins, so called nuclear transport receptors (NTRs). The permeability barrier and its selectivity arise from an assembly of protein domains that are rich in phenylalanine-glycine repeats (FG repeat domains). These domains are natively unfolded and grafted at high density to the NPC channel walls. NTRs can interact with the FG repeat domains, thereby facilitating translocation of NTR-bound cargo. The supramolecular organization of the nuclear pore permeability barrier and the mechanism behind selective transport remain insufficiently understood. Our goal is to understand the relation between the organizational and dynamic features of FG-nucleoporin assemblies, their physicochemical properties, and the resulting biological functions. Using an approach that combines tailor-made biomimetic in vitro model systems, surface-sensitive in situ analysis techniques, and polymer physics theory, we will quantitatively study these relationships on the supramolecular level, a level that – for this type of assemblies – is hardly accessible with conventional biological and biophysical approaches. The model systems will be well-defined allowing tight control over composition and supramolecular structure. In a second step, we will apply the obtained knowledge and construct a biosynthetic in vitro system that performs active, directed macromolecular transport. If successful, this highly interdisciplinary project will greatly increase our mechanistic understanding of nuclear transport. It will also enable the development of novel biotechnology such as species-selective molecular separation devices.";166336,2;166336,2;FP7-PEOPLE-2012-IEF;/MC-IEF;ASOCIACION CENTRO DE INVESTIGACION COOPERATIVA EN BIOMATERIALES- CIC biomaGUNE;ES;;;/SCI;1;0;0;1;0;0 103602;302123;Irish orthography;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IIF;FP7;A Psycholinguistic Investigation of Irish Orthography and Reading;2013-01-14;2015-01-13;;"A major issue for language learners at all levels is the development of literacy skills. Although Irish, the first official language of the Irish Republic, uses the same alphabetic system as English, the very distinct conventions for phoneme-grapheme (sound-symbol) correspondences in the two languages have been shown to present major challenges for English-speaking learners of Irish. Children in Irish schools, acquiring literacy in two languages at once, show significantly greater difficulty learning to read Irish than English. Adult learners already literate in English struggle with Irish orthography and tend to give English values to the spellings, resulting in persistent pronunciation difficulties. The proposed collaborative research between a linguist (the applicant) and a psychologist (her Irish colleague) has the aims of: i. Developing a clearer understanding of the problems that learners face in acquiring Irish reading skills, and ii. Producing a psychologically and linguistically sound analysis of Irish orthography, for use in promoting interdisciplinary scientific discourse on more effective approaches to teaching reading.";266722,6;266722,6;FP7-PEOPLE-2011-IIF;/MC-IIF;UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN;IE;;;/SCI;1;0;0;1;0;0 107204;329264;EcoEvolClim;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IEF;FP7;Conservation and management of Mediterranean freshwaters under climate change: An eco-evolutionary and socio-economic modelling framework;2013-05-06;2015-05-05;;"There is increasing acceptance of the existence of a bi-directionality that intertwines ecological and evolutionary dynamics on the short time scales most relevant to conservation and management. Climate change and anthropogenic pressures are key drivers and accelerators of the short-term dynamic feedbacks resulting from these bi-directional interactions. Consequently, understanding how rapid climate-driven evolutionary and adaptive processes can influence ecological dynamics is crucial for defining ecosystem conservation and management strategies under ongoing global change. This is particularly relevant in freshwater ecosystems, where the impacts of climate change on ecosystem functioning threaten the implementation of several environmental directives, conventions and protocols, especially the European Water Framework Directive (WFD). The researcher proposes to evaluate how climate change will affect eco-evolutionary dynamic feedbacks under different river basin management scenarios at multiple spatio-temporal scales, using Mediterranean brown trout as model system. This will serve as a basis to simulate the long-term dynamics of biological reference conditions, ecological thresholds, restoration targets, and system recovery trajectories of Mediterranean mountain trout rivers. The researcher will use an innovative multidisciplinary and interdisciplinary approach, combining (i) statistical modelling of spatio-temporal patterns of climatic events and anthropogenic disturbances, (ii), molecular genetics and (iii) individual-based and eco-evolutionary modelling, to generate new tools for the conservation and management of Mediterranean salmonid freshwater systems under the WFD. The project aims to synthesize and harmonize the links among socio-economy, ecosystem conservation and eco-evolution disciplines into a coordinated and coherent modelling framework, with potential application to complex real-world problems, especially regarding the implementation of the WFD.";161968,8;161968,8;FP7-PEOPLE-2012-IEF;/MC-IEF;HELMHOLTZ-ZENTRUM FUER UMWELTFORSCHUNG GMBH - UFZ;DE;;;/SCI;1;0;0;1;0;0 102917;290562;MULTIWAVE;ONG;FP7-IDEAS-ERC;ERC-AG-PE2;FP7;Multidisciplinary Studies of Extreme and Rogue Wave Phenomena;2012-04-01;2016-09-30;;MULTIWAVE is an interdisciplinary project at the frontiers of mathematics, physics and engineering which will explore important open questions in nonlinear wave propagation and the emergence of extreme events. The work necessitates a Co-Investigator approach in order to carry out coordinated analytical, numerical and experimental studies of the nonlinear effects that form the subject of the proposal. The project builds on recent international developments in the field of nonlinear waves led by the co-investigators that have shown how analogies between optical systems and the deep ocean provide new insights into the generation of the infamous hydrodynamic rogue waves on the ocean. These results, which have led to the first experimental confirmation in 2010 of analytic predictions of hydrodynamics that have remained untested for 25 years, have now opened up the possibility for an optical system to directly study the dynamics and statistics of extreme nonlinear wave shaping. This is a tremendous advance comparable to the introduction of optical systems to study chaos in the 1970s, and the co-investigators aim to be at the forefront of this research effort. Core theoretical elements in the project will uncover the fundamental mechanisms underlying the emergence of large scale coherent structures from a turbulent environment, and resolve basic questions of energy transport in the presence of nonlinearity. These analytical studies will be complemented by numerical simulations and laboratory experiments in optical systems. Specifically, recent advances in optical technology will enable the benchtop development of an “optical wave tank” that will accurately simulate multiple propagation scenarios in hydrodynamics and ocean systems. Emphasis will be placed on extreme rogue wave events which are difficult or even impossible to study quantitatively in their natural oceanic environment.;1831800;1831800;ERC-2011-ADG_20110209;/ERC-AG;UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN;IE;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FR;"/PSE;/SCI";1;0;0;1;0;0 99152;269142;CLUDS;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-IRSES;FP7;Commercial Local Urban District Programme;2011-04-01;2014-03-31;;"The proposal is based on a research project integrated with a higher education agenda finalized to explore a new approach in delivering and implementing integrated urban policies and programmes. The proposal intends to explore the potential of a new tool for renovating degraded public spaces and improving the attractiveness and accessibility of deprived urban areas by focusing on the high potential of local commercial activities. The exploration is oriented to the implementation of an innovative tools: CLUDs, Commercial Local Urban Districts, aimed at emphasizing the strategic role of small retails -handcraft and typical food- in reinforcing the sense of community, reducing transportation costs and contributing to the creation of attractive urban environment, thus producing increase of private investments. The CLUDs are designated areas, reflecting the rationale of Economic Opportunity Zones. In particular, the thematic specification of the CLUDs is related to local small retail associations that can be occurred on typical local production. The implementation of the programme is based on a networking of four EU universities (Reggio Calabria, Salford, Aalto, Rome) and two USA universities (Boston and San Diego), which all hold the leading positions in planning education, training and research in their countries. Partners will exchange staff members, early stage and Experienced researchers, around yearly seminars/meetings, workshops, and a final international symposium. The core of this network activity regards: Joint research and training activities on two main topics - public/private partnership (PPP) and urban regeneration; an international symposium on PPP in urban regeneration process. The expected result is to bring together an international and interdisciplinary group of research team for the purpose of forming an excellent centre of synergy in research and innovation transfer in the field of PPP applied to urban regeneration actions and policies.";722400;638400;FP7-PEOPLE-2010-IRSES;/MC-IRSES;UNIVERSITA DEGLI STUDI MEDITERRANEA DI REGGIO CALABRIA;IT;"AALTO KORKEAKOULUSAATIO SR;SVERIGES LANTBRUKSUNIVERSITET;THE UNIVERSITY OF SALFORD;UNIVERSITA DEGLI STUDI DI ROMA LA SAPIENZA";"FI;SE;UK;IT";"/EMP;/SOC";1;0;0;1;0;0 106576;316546;HYTECH;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-ITN;FP7;HYDRODYNAMIC TRANSPORT IN ECOLOGICALLY CRITICAL HETEROGENEOUS INTERFACES;2013-01-01;2016-12-31;;"Physical, biochemical and ecological processes in natural water bodies have been the subject of intense research over the past decades by scientists of different expertise. Environmental studies related to natural water bodies are a relatively new area of research, spanning over no more than fifty years. The dawning of environmental studies in the late 20th century has seen developments mainly confined to individual classical areas of expertise, with relatively small degree of interactions among specialities. The development of a truly interdisciplinary approach to environmental studies in a holistic perspective appears one of the main challenges of the new century. This project aims at the training of new technical and scientific figures which can bring innovation in environmental applications and problem solving. The training activity will cover the transport of inorganic and organic matter, including solutes, colloids and sediments in river flows and across the boundary interfaces. Understanding of transport mechanism is a predestined stepping stone towards the ability to assess the vulnerability of the natural environment to anthropogenic stresses. The crucial role of heterogeneities of the stream geometry, of the nature and composition of interfacial matter, and of transported matter, will be emphasized by appropriate experimental and mathematical tools. Direct observations and measurements of transport and ecological processes, using up-to-date instrumentation and investigation procedures, will play a major part in the research and training programme. The participation of the private sector in the training activities will be a key element to guarantee the direct transfer of methods and results into the professional and technical market. The trainees will build specific competence in modern environmental technologies, achieve state-of-the-art knowledge and practical skills building on an existing academic degree in engineering or environmental sciences.";3770019,11;3770019,11;FP7-PEOPLE-2012-ITN;/MC-ITN;UNIVERSITA DEGLI STUDI DI PADOVA;IT;"THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN;GERSTGRASER CHRISTOPH GERSTGRASER INGENIEURBURO FUR RENATURIERUNG GIR;THE UNIVERSITY OF SHEFFIELD;STICHTING NIOZ, KONINKLIJK NEDERLANDS INSTITUUT VOOR ONDERZOEK DER ZEE;WET ENGINEERING SRL;TECHNISCHE UNIVERSITAET BRAUNSCHWEIG;GHT PHOTONICS SRL;POLITECNICO DI MILANO;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;UNIVERSITY OF BRADFORD";"UK;DE;NL;IT;FR";/LIF;1;0;0;1;0;0 98258;267763;ULTRALASER;ONG;FP7-IDEAS-ERC;ERC-AG-PE7;FP7;ULTRALONG FIBRE LASERS;2011-05-01;2016-04-30;;"The project aims to develop a new research concept of ultra-long fibre lasers. The novelty of the concept is in the ground-breaking idea to use laser in the communication applications as a transmission medium rather than as a source of radiation. Ultra-long Raman fibre lasers (first demonstrated in 2005 by the Aston Photonics Research Group led by the applicant) present an area of interdisciplinary research at the interface of high-speed communications, laser physics, optical signal processing, nonlinear science, and mathematical theories of wave turbulence and disordered systems. The project will explore a broad range of research directions emerging from our original proposal of using ultra-long Raman fibre laser technique for quasi-lossless optical transmission with a focus on the four major areas: (i) communications - the development of advanced cross-domain (both in space and frequency) flat-gain, zero power excursion transmission schemes; development of long reach non-repeatered fibre transmission links based on the concept of quasi-lossless fibre spans; (ii) secure communications fundamentally new non-quantum approaches to key distributions using ultra-long laser; (iii) laser science up-scaling of pulse energy to record levels in mode-locked lasers by substantial increase of fibre laser cavity; new types of lasers, including ultra-long random lasers and “modeless” ultra-long lasers; (iv) underlying physics and applications of ultra-long fibre laser optical wave turbulence in fibre lasers; new distributed sensing techniques using ultra-long Raman fibre laser. The proposed program will be unique internationally and will combine the symbiotic development of new scientific ideas and techniques based on the concept of ultra-long fibre laser with the practical engineering design considerations of immediate and future technology applications.";1659771;1659771;ERC-2010-AdG_20100224;/ERC-AG;ASTON UNIVERSITY;UK;;;"/PSE;/ICT;/TEL;/NET";1;0;0;1;0;0 108528;330713;MAPKinDROUGHT;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IEF;FP7;MAPK signalling network to adapt leaf growth to drought conditions;2013-05-01;2015-04-30;;"Drought stress signal is sensed either directly, e.g. in root cells, or indirectly through systemic spread of the signal by hormones and other messenger molecules, and the information is processed through complex signaling pathways to elicit growth adaptation responses. MAPK signalling pathways, a fundamental circuitry of stress signalling, constitute a hierarchical three-tiers system of protein kinases: MEKK, MEK and the MAPK, which phosphorylate specific substrate proteins, thereby changing cellular behavior. Both my lab in Szeged and the Bogre lab at Royal Holloway performed an- gene activation screening for stress-regulating processes, and found MKK7 and MKK9 and two downstream MAPKs, MPK3 and MPK6 to lead to stress adaptation and to regulate plant growth. The overall aim of the proposed research is to identify the targets of the MKK7/MKK9 – MPK3/MPK6 drought-responsive MAPK signaling pathway, and link these to the growth adaptation of plants under drought stress conditions. To do this we will perform: (i) unbiased phosphoproteomics screen for MAPK targets using mimicked drought conditions with mannitol treatment and the inducible MKK7/MKK9 lines, (ii) computational predictions of MAPK substrates involved in drought responses, (iii) targeted approaches to test MAPK phosphorylation of key regulators in plant growth regulation, the RBR transcriptional repressor complex. We aim to map the phosphorylation sites on RBR and DPB and on at least three newly identified MAPK substrates, mutate these sites and transform the mutant genes back to Arabidopsis wild type plants and into lines with altered MKK7/9 signaling pathway. Growth phenotyping of these lines under control and drought stress conditions should link this MAPK pathway to drought adaptation. In the course of the project I will obtain training in interdisciplinary research; proteomics, computational biology, and gain transferable skills to become an all rounded scientist.";221606,4;221606,4;FP7-PEOPLE-2012-IEF;/MC-IEF;ROYAL HOLLOWAY AND BEDFORD NEW COLLEGE;UK;;;/SCI;1;0;0;1;0;0 95216;241918;COMPOSITE;ONG;FP7-SECURITY;SEC-2009-6.2-01;FP7;COmparative POlice Studies In The Eu;2010-08-01;2014-07-31;http://www.composite-project.eu;Police forces in the EU face serious challenges. Integration in the EU has increased the need for cross force collaboration. Technology has created new capabilities for criminals but also possibilities for the police. Changes in the public opinion and in political expectations have created extra challenges. Responses to these challenges and exploitation of opportunities require major changes to the culture and structure of police forces, but these are far from trivial and how they need to be implemented differs from one country to another. So far, change management in police organizations has not been addressed in a comparative interdisciplinary study with a European scope. Based on a study of police forces in 10 countries across Europe COMPOSITE will improve the planning and execution of change initiatives in the police, show how these projects can be better aligned with the cultural and societal context per country and explain how the negative process effects can be mitigated. A further aim is to improve both the individual police organization per country and joint European capabilities. The project delivers: 1.A comparative strategic analysis of strengths, weaknesses, opportunities and threats for police organizations in 10 European countries and best practices to meet current and future challenges. 2.A comparative analysis of planning and execution of the change processes, focusing on the impact of leadership, professional and organizational identities and societal expectations. 3.A toolbox containing instruments for training and consultancy and the Annual European Police force monitor to plan and execute changes responding to known and yet unknown challenges and opportunities. The consortium contains universities, business schools, police academies, a technological research institute and consultancy firms. Police forces from the 10 countries are involved in the research and the dissemination phase of the project and they intend to use the results.;8904352,73;6623303;FP7-SEC-2009-1;/CP;ERASMUS UNIVERSITEIT ROTTERDAM;NL;"UNIVERSITEIT ANTWERPEN;UNIVERSITATEA BABES BOLYAI;Masarykova univerzita;THE UNIVERSITY OF SHEFFIELD;FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.;UNIVERSITY ST KLIMENT OHRIDSKI BITOLA;UNIVERSITY OF DURHAM;POLITIEACADEMIE-LANDELIJK SELECTIE EN OPLEIDINGSINSTITUUT POLITIE;FUNDACION ESADE;Fachhochschule der Polizei des Landes Brandenburg;FORMIT - Fondazione per la Ricerca sulla Migrazione e sulla Integrazione delle tecnologie;CAPGEMINI TELECOM MEDIA DEFENSE;UNIVERSITEIT UTRECHT;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS";"BE;RO;CZ;UK;DE;MK;NL;ES;IT;FR";/SEC;1;0;0;1;0;0 107977;313617;SWELL-FER;ONG;FP7-IDEAS-ERC;ERC-SG-SH3;FP7;Subjective well-being and fertility;2013-04-01;2019-03-31;;"The project is about subjective well-being (SWB) and demographic behaviour, with a particular focus on fertility in advanced societies, across time and space. The project is motivated by the fact that European and other advanced industrialized countries have for decades experienced below-replacement fertility levels, which are now posing dramatic challenges to ageing population structures. Cross-sectional and temporal variations in fertility remains an unsolved puzzle for current theories of below-replacement fertility. The argument put forward in this project is that SWB may be the missing link in the understanding of why countries differ so significantly in fertility. The project has a strong interdisciplinary perspective with the following aims: - to advance the understanding of the complex link between SWB and fertility, bringing together a longitudinal perspective with a comparative perspective; - to examine the role of policies, welfare provision and social norms operating at different levels, addressing possible policy measures that would improve the SWB of individuals and couples, leading eventually to increased fertility - to communicate findings and stimulate the academic and policy debate on how SWB matters for fertility, highlighting the relevance of SWB for future data collection efforts and the potential use of SWB for fertility projections; The project relies upon secondary data sources, both longitudinal and comparative in nature. The assessment of SWB and fertility requires statements about causality and interactions with the relevant context. By explicitly addressing the linkages between SWB and fertility in a systematic way, the project will address an important gap in the literature, helping to modify mainstream theoretical frameworks for the understanding fertility variation and contributing to the creation of a new paradigm of post-transitional fertility theory";1052053;1052053;ERC-2012-StG_20111124;/ERC-SG;UNIVERSITA COMMERCIALE LUIGI BOCCONI;IT;COLLEGIO CARLO ALBERTO - CENTRO DI RICERCA E ALTA FORMAZIONE;IT;/SOC;1;0;0;1;0;0 87406;204905;RANK;ONG;FP7-IDEAS-ERC;ERC-SG-SH5;FP7;The Formation and Visualisation of the Social and Political Order of Princes in late Medieval Europe. A Comparative Study between the Empire and England;2008-10-01;2014-09-30;;This project examines the formation and differentiation of princely elites in pre-modern European rank societies. The project concentrates on the late Middle Ages (1200–1500), a key period in these processes, with geographic focus on the Empire and England. In both polities new princely elites emerged during this period. Yet, they did so in the context of the establishment of two different monarchical principles, the elective kingship in the Empire and the hereditary kingship in England. In the Empire, the electoral princes became a distinctive group and constituted themselves as the pillars of the imperium. In England, the title of duke appears to have been introduced to distinguish members of the royal family from other magnates. In examining these complex social and political processes in both polities the project contributes to establish a typology of different ways of constructing societies in pre-modern Europe using an interdisciplinary, comparative approach. The project combines history, architectural and art history, archaeology and semiotics to analyse princely actions, princely architecture and heraldry. In so doing we will endeavour to determine the strategies developed and deployed by princes in late medieval Europe to represent and improve their rank and thus their significance. The comparison sheds light on several key issues such as whether the emperorship, unique in Europe, enabled the development of a king-like position for (electoral) princes, and how in different political contexts the position of the magnates in relation to each other and the king was communicated and perpetuated. This project breaks new ground on several frontiers. Interconnecting different disciplines, it crosses existing subject boundaries and thus opens up new ways of fruitful cooperation. By comparing the Empire with England the project also transgresses the traditional boundaries of national history, thus helping to establish a European perspective in medieval studies.;900000;900000;ERC-2007-StG;/ERC-SG;RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG;DE;;;/SOC;1;0;0;1;0;0 192258;625116;MICROPEP;ONG;FP7-PEOPLE;FP7-PEOPLE-2013-IEF;FP7;Synthetic Polypeptides with Well-Defined Microstructures and Biological Activity;2015-02-16;2017-02-15;;"Peptides are nature’s expression language and as such perform vital roles in living organisms. They are highly functional and produced naturally with a precision that is unprecedented in synthetic polymers. Synthetic polypeptides present a promising alternative as they combine the accessibility of synthetic polymers with functionality and biocompatibility of natural peptides. They are thus ideally suited as a new (commercial) renewable and sustainable polymer materials platform if some practical hurdles in polymerisation control can be overcome. In this project, new routes for the synthesis of polypeptides will be explored that are inexpensive, scalable and reproducible and allow the tuning of polypeptide properties by copolymerisation. While the approach to be taken is generic, our efforts will focus on the synthesis of glycosylated polypeptides as mimics of glycoproteins. Glycoproteins are important in many biological processes from signalling to infection and are thus considered the next generation pharmaceutical products. While natural glycopeptides are highly complex in structure, this project aims at structurally simplistic yet bioactive synthetic glycosylated polypeptides by enhanced polymerisation control. This is a highly interdisciplinary project at the interface of polymer chemistry, combinatorial chemistry and life science. The applicant’s diverse experience makes her an ideal match for this work. The project also brings together two academics from world class institutions with complementary expertise that provides a unique environment for the applicant to develop her skills and accelerate her academic career.";175974,6;175974,6;FP7-PEOPLE-2013-IEF;/MC-IEF;TECHNISCHE UNIVERSITEIT EINDHOVEN;NL;;;;1;0;0;1;0;0 107461;334493;CompBAND;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-CIG;FP7;Computational Studies of the Biogenic Amines of the Brain for Targeting Neurological Diseases;2013-04-01;2017-03-31;;The main purpose of this computational research is to improve the understanding of a relation between features, metabolic pathways and signal transduction of amine neurotransmitters and the treatment of neurological diseases. Brain monoaminergic systems have been extensively implicated in the etiology and course of various neurodegenerative disorders, and their binding proteins such as receptors, transporters and common metabolic enzymes are the starting points for development of tools to diagnose and drugs to treat specific clusters of symptoms. Therefore, the research described here will be focused on two particular biological systems: monoamine oxidase enzymes (MAOs) responsible for regulating amine levels in the synaptic region, and histamine H1 and H2 receptors that regulate the activity of allergic and inflammatory mediator histamine. The work on MAO should aid in revealing molecular mechanisms of MAO-catalyzed amine degradation to their corresponding aldehydes, as well as of irreversible MAO inhibition related to the pharmacotherapy of depression, Parkinson disease and age-related cognitive disorders. This should help improve efficiency and reduce adverse effects of commercially available drugs, and should suggest novel classes of active compounds as transition state analogues. In joint computational/experimental efforts, studies on histamine receptors should unlock the secrets of receptor's distinction between agonist and antagonist binding using receptor deuteration, being of major relevance for molecular pharmacology. Overall, it is intended to identify ubiquitous trends and features that are applicable well beyond the scopes of these individual investigations. The proposed research is in general highly interdisciplinary with the promise of industrial applications, since it bridges the gap between fundamental understanding of biological systems and preclinical medicine combining modern methods of computational biochemistry with pharmacological approaches.;100000;100000;FP7-PEOPLE-2012-CIG;/MC-CIG;RUDER BOSKOVIC INSTITUTE;HR;;;/LIF;1;0;0;1;0;0 94261;246998;ELECSPECIONS;ONG;FP7-IDEAS-ERC;ERC-AG-PE4;FP7;Electronic spectra of cold, large interstellar ions;2010-05-01;2015-04-30;;The purpose of this project is to measure for the first time gas-phase spectra of large carbon containing cations, at low temperatures, which are of astrophysical importance. Knowledge of electronic spectroscopy of such molecules is also of pertinence in a number of areas of chemistry and physics, enabling their identification in planetary atmospheres, flames and plasmas and as intermediates in chemical reaction dynamics. This project is interdisciplinary, bridging the areas of chemistry, physics, and astrophysics. It encompasses state of the art techniques of chemical physics and aims at obtaining information to solve the long standing enigma in observational astronomy, the identification of some of the molecules causing absorption of starlight in diffuse interstellar clouds. The project uses ion trapping technology, whereby mass-selected species are held in a radio-frequency field and the vibrations and rotations are relaxed by collisions with cold helium to typical interstellar temperatures of 10-30 K. The electronic spectra of a number of cations, selected on the basis of their special properties including those of bare carbon chains, rings and fullerenes, polycyclic aromatic hydrocarbon cations and their protonated forms will be measured using new detection schemes. The first approach is based on photo-induced charge transfer which is turned on upon laser excitation and the second uses the possibility of rare-gas complexation in the ground but not excited state.;1898624;1898624;ERC-2009-AdG;/ERC-AG;UNIVERSITAT BASEL;CH;;;/PSE;1;0;0;1;0;0 106987;320832;IMAGINE;ONG;FP7-IDEAS-ERC;ERC-AG-PE4;FP7;Imaging Magnetism in Nanostructures using Electron Holography;2013-04-01;2018-03-31;;"'Future developments in the control, functionalization and manipulation of magnetic nanoparticles and nanoscale magnetic devices require an understanding of collinear and non-collinear spin configurations and correlated changes of electronic structure on the sub-nanometer scale. In this project, an experimental methodology will be developed to allow magnetic spin structures in differently shaped nanomagnets to be visualized quantitatively and correlated with their crystallographic, compositional and defect structures. The project is based on the development of electron holography in the transmission electron microscope. It aims to provide quantitative measurements of internal magnetic fields in nanoparticles and devices that have characteristic dimensions of between 2 and 20 nm with a spatial resolution of better than 1 nm, both in projection and in three dimensions. Developments in instrumentation will allow the measurements to be acquired in situ in the electron microscope at elevated and reduced specimen temperatures and in the presence of oxidizing and reducing gases. The project is highly interdisciplinary, requiring close collaboration between scientists working on nanoparticle synthesis, device fabrication, magnetic modeling, computational mathematics and characterization techniques. It will provide a powerful new analytical tool at the frontiers of the highest spatial resolution analysis of spin and electronic structures that will have far-reaching impact beyond a specific research domain, not only in fundamental magnetism but also for applications that include magnetic recording, spintronics, catalysis and biomedical applications of magnetic nanoparticles. The methodology will also benefit European industry by providing a new leading edge in the fast growing international market of in situ transmission electron microscopy.'";2499140;2499140;ERC-2012-ADG_20120216;/ERC-AG;FORSCHUNGSZENTRUM JULICH GMBH;DE;"UNIVERSITAET DUISBURG-ESSEN;THE UNIVERSITY OF EDINBURGH";"DE;UK";/PSE;1;0;0;1;0;0 107027;334452;MapRePort;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-CIG;FP7;Mapping and assessment of research portfolios;2013-04-01;2017-03-31;;This proposal aims to develop an analytical framework for the mapping and assessment of research portfolios. The notion of “research portfolio” is increasingly used by funding agencies. However, there is no clear understanding and very little research on how to define, map and assess a research portfolio. Here we aim to develop a multi-method approach to investigate a research portfolio of a given disease. We build on evolutionary perspectives on science dynamics, using concepts and methods from Science Technology Studies, Information Sciences and the Innovation Studies side of Evolutionary Economics. The work plan is to sequentially investigate three case studies: cervical cancer, avian flu and depression. For each case, we first carry out a scoping study to tentatively delineate the research on a disease. Second, we map the research lines a portfolio comprises, on the basis of publications. Third, we explore the diversity of a portfolio and the complementarities among different research lines under various analytical perspectives. Fourth, we use project databases from funding agencies in order to estimate resources associated with a given research line. Fifth, we interview stakeholders using a multi-criteria analysis tool to assess their valuation of the different research lines. This analysis produces a map of the research portfolio of a given disease, and its assessment under various criteria by stakeholders. This grant supports my integration to Ingenio (CSIC-UPV), a Science, Technology and Innovation Research centre that I have recently joined with a tenure-track fellowship. The grant allows me recruit postdoctoral fellows as research assistants, which is important to consolidate our new research group on medical innovation in Ingenio, as well as to further link myself and Ingenio in European networks of excellence in the interdisciplinary area of S&T policy research.;100000;100000;FP7-PEOPLE-2012-CIG;/MC-CIG;AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS;ES;;;/LIF;1;0;0;1;0;0 93523;244047;CORFU;ONG;FP7-ENVIRONMENT;ENV.2009.1.3.3.1;FP7;Collaborative research on flood resilience in urban areas;2010-04-01;2014-06-30;;Collaborative research on flood resilience in urban areas (CORFU) is an interdisciplinary international project that will look at advanced and novel strategies and provide adequate measures for improved flood management in cities. The differences in urban flooding problems in Asia and in Europe range from levels of economic development, infrastructure age, social systems and decision making processes, to prevailing drainage methods, seasonality of rainfall patterns and climate change trends. Our vision is that this project will use these differences to create synergies that will bring new quality to flood management strategies globally. Through a 4-year collaborative research programme, the latest technological advances will be cross-fertilised with traditional and emerging approaches to living with floods. The overall aim of CORFU is to enable European and Asian institutions to learn from each other through joint investigation, development, implementation and dissemination of strategies that will enable more scientifically sound management of the consequences of urban flooding in the future. Flood impacts in urban areas – potential deaths, damage to infrastructure and health problems and consequent effects on individuals and on communities – and possible responses will be assessed by envisaging different scenarios of relevant drivers: urban development, socio-economic trends and climate changes. The cost-effectiveness of resilience measures and integrative and adaptable flood management plans for these scenarios will be quantified. CORFU is structured in six Work Packages. WP1 will look at drivers that impact on urban flooding. WP2 will enhance methodologies and tools for flood hazard assessment based on urban flood modelling. WP3 will improve, extend and integrate modern methods for flood impact assessment. WP4 will aim to assess and enhance existing flood risk management strategies. WP5 will disseminate the outputs. WP6 will co-ordinate the project.;5144169,67;3490000;FP7-ENV-2009-1;/CP-FP-SICA;THE UNIVERSITY OF EXETER;UK;"CHINA ACADEMY OF URBAN PLANNING AND DESIGN;INTERNATIONAL CENTER FOR URBAN WATER HYDROINFORMATICS RESEARCH & INNOVATION FOUNDATION;INSTITUTE OF WATER MODELLING;UNIVERSITE DE NICE SOPHIA ANTIPOLIS;TECHNISCHE UNIVERSITAT HAMBURG-HARBURG;Hamburgisches WeltWirtschaftsInstitut gemeinnützige GmbH;BEIJING UNIVERSITY OF TECHNOLOGY;AREP Ville;BEIJING MUNICIPAL INSTITUTE OF CITY PLANNING AND DESIGN;NATIONAL TAIWAN UNIVERSITY;DHI;INDIAN INSTITUTE OF TECHNOLOGY BOMBAY;Hydrometeorological Innovative Solutions;CETAQUA, CENTRO TECNOLOGICO DEL AGUA, FUNDACION PRIVADA;CRANFIELD UNIVERSITY;Dura Vermeer Groep NV";"CN;KR;BD;FR;DE;TW;DK;IN;ES;UK;NL";"/MET;/ENV";1;0;0;1;0;0 106772;324387;RIMACON;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IAPP;FP7;Risk Management Software System for SMEs in the Construction Industry;2013-04-01;2017-03-31;;The construction sector is one of Europe's biggest industries accounting for 10% of Gross Domestic Product with approximately 92% of manufacturers being SMEs. This sector directly employs 12 million EU citizens and 26 million workers are dependent on the sector. However, due to the global economic crisis, the last few years have been full of uncertainty for many companies in the construction and engineering industry. These companies are facing fierce competition and winning new contracts as well as delivering on schedule and on budget is fundamental to their survival. Core to these problems are, enterprises and more especially SMEs are operating in a dynamic business environment with constant exposure to risk leading to underperformance, low productivity and sometimes businesses could stop trading overnight. This project therefore, aims at developing a cost effective, user friendly risk management system, which evaluates, monitors, and reviews both imminent and impending risks with a view to completely eliminate or minimise their impact. RiMaCon consortium wishes to challenge and overcome the current non trivial, interdisciplinary and intersectoral barriers currently preventing the development and implementation of efficient risk management systems in SMEs. It will therefore design and develop a robust, reliable, and sustainable risk management prototype system suitable and affordable for the construction SMEs, possibly in a software format or a portal. This risk management prototype will be dynamic, flexible to adapt to different construction contexts. RiMaCon has already carried out preliminary survey / investigation and confirmed this need especially for SMEs who are under resourced, vulnerable and also lack the technology to develop a robust risk management system. RiMaCon (two Universities and two SMEs) is balanced in terms of expertise and knowledge to tackle this problemn and will work with a large database of construction SMEs who would provide the data.;921317,23;921317,23;FP7-PEOPLE-2012-IAPP;/MC-IAPP;UNIVERSITY OF WOLVERHAMPTON;UK;"DANSK BRAND- OG SIKRINGSTEKNISK INSTITUT FORENING;COMPUTORS LIMITED;VETTORAZZO COSTRUZIONI SRL;ZAPADOCESKA UNIVERZITA V PLZNI;THYME SOFTWARE LIMITED";"DK;UK;IT;CZ";/LIF;1;0;0;1;0;0 105890;314310;TelliSys;ONG;FP7-TRANSPORT;GC.SST.2012.3-1.;FP7;Intelligent Transport System for Innovative Intermodal Freight Transport;2012-12-01;2015-11-30;;"The trend towards increasing transport demand - prerequisite for economic growth - is still challenging the European transport system. On the other hand Europe aims to reduce emissions dramatically. A crucial measure achieving this ambitious aim is to lower transport emissions by increasing the share of inherently more resource-friendly modes of transport. The “Intelligent Transport System for Innovative Intermodal Freight Transport” (TelliSys) will actively promote the EU’s objective of optimizing the performance of intermodal logistic chains and will provide smooth and cooperative interactions between different modes of transport. Scientific aim is to develop an intelligent transport system that is applicable for road (in line with Directive 96/53/EC), rail, short sea and inland shipping, which consists of a modular set of volume-optimised and traceable MegaSwapBoxes (MSB), an adapted trailer and a tractor for the road transport. Ideas and contributions from the consortium together with the advice of outstanding key players of the transport business guarantee the holistic approach and market acceptance of the project outcomes. TelliSys is the follow-up of the successful TelliBox project and the now modular MSB will be based on the unique selling propositions like stackability, three openable sides, three meters loading height, trimodality, pallet wide and cargo security. In addition, the new developed tractor will provide an extra low fifth wheel height (low deck) designed for volume-optimised road transport and the adapted trailer will be flexible to transport conventional loading units as well as the new MSBs. Within TelliSys an interdisciplinary European consortium of experts in the field of freight forwarding, manufacturing and science will deliver concepts, prototypes and a proof of concepts via extensive test runs. A complementary bundle of scientific evaluation methods, profitability calculations and risk mitigation actions will guarantee the project succes";4284414,85;2915374;FP7-SST-2012-RTD-1;/CP-FP;RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN;DE;"GOODYEAR SA;Wecon GmbH Nutzfahrzeuge-Container-Technik;DAF TRUCKS NV;GEFCO DEUTSCHLAND GMBH;HEIKO SENNEWALD;Wesob Spolka z Ograniczona Odpowiedzialnoscia;EUROPEAN INTERMODAL ASSOCIATION";"LU;DE;NL;PL;BE";/SCI;1;0;0;1;0;0 88534;206198;RPPV;ONG;FP7-IDEAS-ERC;ERC-SG-SH3;FP7;Representation and Processing of Pitch Variation in Tonal Languages;2008-11-01;2014-10-31;;In connected speech, spoken words may vary considerably from their forms in isolation. Much of the variation is regular. There have been heated debates on whether and how speakers store regular variants in their long-term memory, and how they process them in speech production and comprehension. Most psycholinguistic work, however, focuses on how listeners cope with segmental variation. I propose instead to examine how speakers store and process regular pitch variation. My empirical focus is on Chinese dialects, where pitch changes (tones) are used to distinguish word meanings in isolation, but tonal realization of words in phrases is determined by domain formation and pitch changes within the domain, together known as tone sandhi. Crucially, both how a tonal domain is formed and how sandhi variants are realized within the domain are influenced by a complex mixture of pragmatic, syntactic, and phonological factors. The pitch variation in these dialects thus manifests at all levels of linguistic organization. I hypothesize that the way pitch variation is stored in the mental lexicon and processed during speech production varies according to the types of tone sandhi changes and the constituent structures of sandhi domains. I take an interdisciplinary approach to test this hypothesis. Cross-dialect speech corpora will be compiled to obtain a comprehensive understanding of how pitch variation is conditioned in linguistic contexts. Acoustic and perceptual experiments will be conducted to understand the categorical vs. gradient nature of pitch variation. Both voice onset latencies and speakers’ eye movements during speech will be monitored to tap into the representation as well as the processing of pitch variation. Results of this project will contribute to debates on representation and processing of regular linguistic variation in general, therefore furthering our understanding of human cognition.;600000;600000;ERC-2007-StG;/ERC-SG;UNIVERSITEIT LEIDEN;NL;;;/SOC;1;0;0;1;0;0 89770;231025;BIOSEQANALYSIS;ONG;FP7-PEOPLE;PEOPLE-2007-4-3.IRG;FP7;Computational methods for biological sequence analysis with application to evolution of yeast mitochondrial genomes;2009-01-01;2012-12-31;;Modern molecular biology relies on high-throughput technologies to generate large quantities of data about components of living cells and on sophisticated mathematical and computational techniques for analyzing this data. We will develop new algorithms and probabilistic models in areas of comparative genomics, gene finding, and homology search. In particular, we propose a new class of evolutionary models for modeling changes in exon structure of protein coding genes. These models have applications in gene finding and ancestral sequence reconstruction. We will also develop more efficient methods for homology search in large databases containing families of related sequences. Finally, we will apply both existing and new methods to comparative analysis of mitochondrial genomes in Candida genus. Some of these genomes have linear chromosomes terminated with telomere-like structures similar to eukaryotic nuclear chromosomes, yet of independent evolutionary origin. By studying these sequences, we aim to address fundamental questions of evolution of linear genomes and telomeric regions, and evolution of binding specificity in DNA binding proteins. This interdisciplinary project will be carried out in cooperation with researchers from both computer science and biology at Comenius University in Bratislava.;100000;100000;FP7-PEOPLE-IRG-2008;/MC-IRG;UNIVERZITA KOMENSKEHO V BRATISLAVE;SK;;;"/SCI;/COO";1;0;0;1;0;0 92000;240603;ANSR;ONG;FP7-IDEAS-ERC;ERC-SG-PE2;FP7;Ab initio approach to nuclear structure and reactions (++);2009-12-01;2014-11-30;;"Today, much interest in several fields of physics is devoted to the study of small, open quantum systems, whose properties are profoundly affected by the environment; i.e., the continuum of decay channels. In nuclear physics, these problems were originally studied in the context of nuclear reactions but their importance has been reestablished with the advent of radioactive-beam physics and the resulting interest in exotic nuclei. In particular, strong theory initiatives in this area of research will be instrumental for the success of the experimental program at the Facility for Antiproton and Ion Research (FAIR) in Germany. In addition, many of the aspects of open quantum systems are also being explored in the rapidly evolving research on ultracold atomic gases, quantum dots, and other nanodevices. A first-principles description of open quantum systems presents a substantial theoretical and computational challenge. However, the current availability of enormous computing power has allowed theorists to make spectacular progress on problems that were previously thought intractable. The importance of computational methods to study quantum many-body systems is stressed in this proposal. Our approach is based on the ab initio no-core shell model (NCSM), which is a well-established theoretical framework aimed originally at an exact description of nuclear structure starting from realistic inter-nucleon forces. A successful completion of this project requires extensions of the NCSM mathematical framework and the development of highly advanced computer codes. The '\\' in the project title indicates the interdisciplinary aspects of the present research proposal and the ambition to make a significant impact on connected fields of many-body physics.";1304800;1304800;ERC-2009-StG;/ERC-SG;CHALMERS TEKNISKA HOEGSKOLA AB;SE;;;"/PSE;/SCI";1;0;0;1;0;0 100377;267139;OMICS@VIB;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-COFUND;FP7;VIB International Postdoctoral Program to boost '-omics' technologies throughout the institute;2011-12-15;2017-06-14;;"VIB is a life science centre of excellence in Flanders (Belgium) established in 1996. We have gained valuable experience in selecting, training and employing young researchers, amongst others thanks to our International Ph.D. Program. Only 5 years after the start of this program, VIB’s student population has grown from 275 Belgian students into a dynamic community of nearly 400 students, representing 38 nationalities. The COFUND support will allow VIB to establish a postdoctoral program with ambitions transcending the goals of the current Ph.D. program. Besides the structuring effect resulting from the Ph.D. Program, the COFUND program is designed to further boost the introduction of ‘–omics’ approaches (genomics, proteomics, interactomics, bioinformatics, systems biology …) in the various research groups of VIB. Moreover, the program will provide a platform for interdisciplinary approaches, intensified training opportunities and personalized career coaching . COFUND researchers will become member of one or even two VIB groups for a period of three years. Their postdoctoral project will be designed in close collaboration with the group leader(s) of their choice, with a special focus on further integrating ‘–omics’ approaches in the current research of the group. The new postdocs will be embedded in the VIB community, with access to all centrally organized state-of-the-art technology platforms, training & support activities and institutional information channels. During their stay at VIB, their group leader(s) and VIB’s HR manager will coach them to design their personalized future career path. At VIB, COFUND researchers will do frontline research, enabling them to build an excellent publication record and curriculum in an environment infected by the spirit of excellence in science, technology, and technology transfer. They can build on VIB’s extensive international and industrial network to become full members of the European Research Area and beyond.";7276080;2910432;FP7-PEOPLE-2010-COFUND;/MC-COFUND;VIB;BE;;;"/SOC;/COO;/NET";1;0;0;1;0;0 105933;321876;URBANMUSICS;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-CIG;FP7;Urban musics and musical practices in sixteenth-century Europe;2012-12-01;2016-11-30;;The urban musics and musical practices of sixteenth-century European cities have been studied only rather patchily in terms of geography and partially in terms of urban culture. Renaissance Italian cities, benefiting from a strong cultural historical tradition, have fared relatively well, while music in the urban context in France, Flanders, Germany and England has been considered in a steady trickle of studies over recent decades. The cities of the Iberian Peninsula, however, remain largely unexplored, a situation that derives in part from a peculiarly Spanish music historiographical trend that resulted in a series of studies focusing on cathedral musical life, with little or no consideration of a broader urban context. The preservation of the majority of Spanish sixteenth-century music sources in cathedral archives and the priest-musicologist tradition that persisted in Spain until the1980s were major factors in this trend, factors that also help to explain the still prevailing perception of Spanish musical culture as isolated from, and largely irrelevant to, the European musical mainstream. There is thus a compelling need to review this situation through the identification and analysis of the different musics (written and unwritten), musical practices (official and unofficial) and performative spaces of a city such as Barcelona. As a major Mediterranean port open to France and Italy and a hub for the book trade, Barcelona was clearly not isolated from the rest of Europe, and its urban culture can be analyzed in depth thanks to the wealth of documentary and musical material in the city’s archives. By developing methodologies drawn from cultural history, historical anthropology and ethnomusicology, by which music is considered in the context of urban culture and social interaction and communication from a totality of perspectives, this innovatory and interdisciplinary project will take a step further the mapping of European cultural history.;100000;100000;FP7-PEOPLE-2012-CIG;/MC-CIG;AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS;ES;;;/LIF;1;0;0;1;0;0 106365;323526;AMST;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IAPP;FP7;Advanced Multi-physics Simulation Technology;2013-01-01;2016-12-31;;"'A vast number of engineering applications as diverse as in pharmaceutical, food and processing industry, mining, construction and agricultural machinery, metals manufacturing, energy production and systems biology include a particulate and continuous phase. Although simulation software for either discrete or continuous applications matured during the last decades, to date a large gap for integrated software to describe the interaction between a particulate and continuous phase exists. Therefore, the objective is to develop Advanced Multi-physics Simulation Technology (AMST) as a flexible, extensible and versatile interface for coupling discrete numerical approaches to field problems applicable under industrial standards. The discrete simulation framework is represented by the novel Discrete Particle Method (DPM) that contrary to the classical Discrete Element Method predicts in addition to the kinematic also the thermodynamic state of individual particles in an ensemble. Rather than extending the Discrete Particle Method by continuous solution concepts of field problems such as structural analysis or fluid dynamics, the objective is met by controlling data transfer such as fluid forces, heat and mass transfer between the Discrete Particle Method and available software products for field problems. These targets are successfully achieved by an interdisciplinary approach fostering the transfer of knowledge within an intersectorial partnership of the University of Luxembourg and the German SME inuTech with their complementary expertise. Strategic partners from the academic and industrial sector will contribute by giving expert advice and by providing industrial relevant test cases. Advanced Multi-physics Simulation Technology closes a large technological gap for research and industry, and contributes significantly to multi-physics research in Europe with a high impact on innovative engineering, sustainable intersectorial collaboration and European competitiveness.'";891436;891436;FP7-PEOPLE-2012-IAPP;/MC-IAPP;UNIVERSITE DU LUXEMBOURG;LU;"FLSMIDTH WADGASSEN GMBH;PAUL WURTH SA;inuTech GmbH;LIETUVOS ENERGETIKOS INSTITUTAS";"DE;LU;LT";/LIF;1;0;0;1;0;0 106613;320879;IMPUNEP;ONG;FP7-IDEAS-ERC;ERC-AG-PE8;FP7;Innovative Materials Processing Using Non-Equilibrium Plasmas;2013-02-01;2018-09-30;;"Current bulk materials processing methods are nearing their limit in terms of ability to produce innovative materials with compositional and structural consistency. The aim of this ambitious project is to remove barriers to materials development, by researching novel methods for the processing of engineering materials, using advanced non-equilibrium plasma systems, to achieve a paradigm shift in the field of materials synthesis. These new processes have the potential to overcome the constraints of existing methods and also be environmentally friendly and produce novel materials with enhanced properties (mechanical, chemical and physical). The research will utilise plasmas in ways not used before (in bulk materials synthesis rather than thin film formation) and it will investigate different types of plasmas (vacuum, atmospheric and electrolytic), to ensure optimisation of the processing routes across the whole range of material types (including metals, ceramics and composites). The materials synthesised will have benefits for products across key applications sectors, including energy, healthcare and aerospace. The processes will avoid harmful chemicals and will make optimum use of scarce material resources. This interdisciplinary project (involving engineers, physicists, chemists and modellers) has fundamental “blue skies” and transformative aspects. It is also high-risk due to the aim to produce “bulk” materials at adequate rates and with consistent uniform structures, compositions and phases (and therefore properties) throughout the material. There are many challenges to overcome, relating to the study of the plasma systems and materials produced; these aspects will be pursued using empirical and modelling approaches. The research will pursue new lines of enquiry using an unconventional synthesis approach whilst operating at the interface with more established discipline areas of plasma physics, materials chemistry, process diagnostics, modelling and control.";2499283;2499283;ERC-2012-ADG_20120216;/ERC-AG;THE UNIVERSITY OF MANCHESTER;UK;THE UNIVERSITY OF SHEFFIELD;UK;"/PSE;/MAT;/IND;/CON";1;0;0;1;0;0 102088;293788;PRICE;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-CIG;FP7;Why and how do antifreeze proteins bind ice? An experimental study on the solution and adsorption behaviour of antifreeze proteins;2012-01-01;2015-12-31;;"Many Arctic and Antarctic species, including fish, insects, and plants, survive extreme cold by producing antifreeze proteins (AFPs) that depress the freezing point of their bodily fluids in a non-colligative manner without altering its melting point. The ‘adsorption-inhibition mechanism’ has now been widely accepted to explain how AFPs achieve thermal hysteresis and inhibit ice recrystallisation, but why and exactly how AFPs bind ice is not yet known. This CIG project entitled ‘PRice’ entails an experimental study on antifreeze proteins in solution and at interfaces to identify and better understand key mechanisms by which AFPs function. The fundamental insights that we hope for are also of applied interest as the natural cryoprotective ability of AFPs can be very useful in the preservation of organs and food products upon freeze storage for example. The community contribution to PRice supports the integration of an excellent female researcher (MSc and PhD degrees were awarded with highest distinction) at an outstanding university in Europe. On March 1st 2011, she moved from the Adolphe Merkle Institute of the University of Fribourg in Switzerland to Eindhoven University of Technology (TU/e) in the Netherlands to take up a position as an Assistant Professor (6-year tenure track) within the Macromolecular and Organic Chemistry Group (MOC) of Prof. E. W. (Bert) Meijer and the Institute for Complex Molecular systems. She has an ideal background for this highly interdisciplinary project that will create new synergies between European research institutes and universities through collaborations between experimentalists of various nationalities and scientific backgrounds. The project will significantly advance her future career prospects as it opens up new possibilities to extend previous research activities and supports the establishment of her own subgroup within MOC at TU/e.";100000;100000;FP7-PEOPLE-2011-CIG;/MC-CIG;TECHNISCHE UNIVERSITEIT EINDHOVEN;NL;;;/SCI;1;0;0;1;0;0 90125;225267;MERCURY;ONG;FP7-SSH;SSH-2007-4.3-02;FP7;Multilateralism and the EU in the Contemporary Global Order;2009-02-01;2012-04-30;http://www.mercury-fp7.net;"This project seeks to understand the EU’s contribution to effective multilateralism. We consider evolving and conflicting (culturally-defined) meanings of multilateralism; its uncertain future on a global scale; the EU system of external relations in the light of the Reform Treaty and its implications for the Union's ability to shape multilateralism; and whether and how multilateralism is compatible with the EU’s shift towards inter-regionalism and strategic partnerships. Arguably, the EU has done more than most of its partners to acknowledge new global challenges and rising demand for multilateralism. Its own positions frequently become focal points for international negotiations on conflict resolution. Nevertheless, essential questions remain unanswered about the viability of a European ‘way’ of multilateralism. Can multilateralism be defined in a way that transcends divisions within as well as beyond Europe, between states, nations and cultures, strong and weak, rich and poor? Is there a concept of multilateralism that overcomes theoretical schisms? Is it possible for the EU or its member states (or anyone else) to define and pursue a selfless, benign, credible doctrine of multilateralism, as opposed to one that serves its own interests? The problem of matching supply to demand for effective multilateralism will be the leitmotif for MERCURY, a research programme that will elaborate and clarify forms of multilateralism, develop specific theses about the EU’s contribution to multilateralism, and test them in line with best scientific practice. Its remit extends to the interactions of the EU and its member states with regions outside Europe, strategic partners, and global organisations. It is interdisciplinary, drawing on expertise in law, politics, economics, and international relations. It advances a clear intellectual agenda – to explore, explain, and evaluate different conceptions of multilateralism – while aiming to achieve practical policy relevance.";1975910;1500000;FP7-SSH-2007-1;/CP-FP;THE UNIVERSITY OF EDINBURGH;UK;"FUDAN UNIVERSITY;THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;ISTITUTO AFFARI INTERNAZIONALI;FONDATION NATIONALE DES SCIENCES POLITIQUES;STIFTELSEN STOCKHOLMS INTERNATIONELLA FREDSFORSKNINGSINSTITUT;UNIVERSITAET ZU KOELN;UNIVERSITY OF PRETORIA;UNIVERZITA KARLOVA";"CN;UK;IT;FR;SE;DE;ZA;CZ";/SOC;1;0;0;1;0;0 108763;331494;NEUROSCISOCPOL;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IOF;FP7;Applying neuroscience to social policy and the law: neuromaturation and young adult offending;2013-10-01;2016-09-30;;"This proposal is concerned with the complex and contested application of emerging understandings within neuroscience to issues of law and social policy, with a focus on young adults in the criminal justice system, including those with neurodevelopmental difficulties. The last 30 years have seen remarkable advances in the range of neurosciences. The application of these advances to a wide range of legal and social policy concerns is clear, though also controversial and potentially problematic. The fellowship has three objectives: to facilitate multidisciplinary debate regarding the challenges and possibilities in the application of neuroscience to social policy; to consider the explanations apparent in emerging understandings of neuromaturation of patterns of offending behaviour amongst young adults; and to explore the implications of these emerging understandings for policy and practice within the criminal justice system. The fellowship provides an opportunity for a social policy academic with significant experience researching criminal justice policy and practice to be based in the Murdoch Childrens Research Institute: the preeminent child health research organisation in Australia, recognised globally for its research in neurodevelopment and adolescent health. Under expert supervision, the applicant will review existing neuroscience and associated research, addressing its application to law and social policy, and undertake secondary analysis of longitudinal quantitative survey and neuroimaging data to develop indicators of neurodevelopment applicable to understandings of offending. This will facilitate interdisciplinary debate through a series of workshops engaging policymakers and practitioners, followed by two empirical studies critically exploring current approaches to assessment and intervention. The return phase will enable comparative empirical work, allowing consideration to the potential impact of neuroscience in two highly varied criminal justice systems.";388538,6;388538,6;FP7-PEOPLE-2012-IOF;/MC-IOF;THE UNIVERSITY OF BIRMINGHAM;UK;;;/LIF;1;0;0;1;0;0 108758;328497;VELO MOLO_780;CAN;FP7-PEOPLE;FP7-PEOPLE-2012-IEF;FP7;VEry LOw jitter MOde LOcked laser at 780nm for optical sampling applications;2013-09-02;2015-09-01;;"'The project investigates prospective configuration of pulsed laser source for the use in photonic assister analog to digital converters. This application oriented project is based on strong interdisciplinary linkage and aims to develop compact, efficient and low cost pulsed sources. System requirements for a pulsed laser source are to be met by means of mode-locking from either monolithic laser diode or fibred external cavity system. The core of this project is based on an iterative process of multiple runs and each represents the full process which combines different skills and procedures which include the design, fabrication, testing, modelling and the delivery of an improved design. Throughout the project, the fellow, who owns a solid academic background in laser physics will have the opportunity to perform industrial research and development in a fertile and diversified scientific environment provide by the host institution. This environment will stimulate the fellow to reach professional maturity. This application oriented research will contribute to the European Excellence in the field of photonics.'";194046,6;194046,6;FP7-PEOPLE-2012-IEF;/MC-IEF;III-V LAB;FR;;;/SCI;1;0;0;1;0;0 105608;318306;NEWCOM#;CLO;FP7-ICT;ICT-2011.1.1;FP7;Network of Excellence in Wireless COMmunications #;2012-11-01;2015-10-31;;"NEWCOM# is a Network of Excellence (NoE) proposal submitted in response to challenge FP7-ICT-2011-8 1.1, 'Future Networks'. A group of 14 partners in 14 different countries (12 of which come from the former FP7 NoE NEWCOM\\) decided to capitalize on the high degree of integration in research they already at-tained to build an NoE with the following objectives: i) to produce medium to long term results in the area of design and performance evaluation of wireless networks; ii) to strengthen the integration of partners' re-search activities and agendas, both at the theoretical and experimental levels; iii) to foster Industry-academia cooperation, dissemination, and liaison by making academic research closer to industrial needs and interests; iv) to provide a unique training environment for a new generation of researchers in both theo-retical and experimental research; v) to contribute to the long-term sustainability of the NoE by creating a permanent environment for cooperative research.In a 'Theoretical Research' track, the NEWCOM# researchers will pursue long-term, interdisciplinary re-search on the most advanced aspects of wireless communications like Finding the Ultimate Limits of Com-munication Networks, Opportunistic and Cooperative Communications, Energy- and Bandwidth-Efficient Communications and Networking. A second track will be devoted to the 'EUropean lab of Wireless commu-nications for the future INternet', a federation of three sites in three European Countries that will host re-searchers working on a few general themes like Radio Interfaces, Internet of Things, and Flexible Communi-cation Terminals. The third track will have a number of initiatives to foster excellence like the creation of seasonal schools, a series of publication on journals and books, and an action directed towards strengthen-ing relations with European companies, which will participate to the NoE as 'Affiliate Partners', through a number of in-company dissemination events.";5550980;2845999;FP7-ICT-2011-8;/NoE;CONSORZIO NAZIONALE INTERUNIVERSITARIO PER LE TELECOMUNICAZIONI;IT;"POLITECHNIKA POZNANSKA;TECHNISCHE UNIVERSITAET WIEN;THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;OULUN YLIOPISTO;CENTRE TECNOLOGIC DE TELECOMUNICACIONS DE CATALUNYA;INSTITUTE OF ACCELERATING SYSTEMS AND APPLICATIONS;UNIVERSITE PARIS-SUD;UNIVERSITE CATHOLIQUE DE LOUVAIN;Ecole Superieure D'Eiectricite;UNIVERSITAT POLITECNICA DE CATALUNYA;Bilkent Üniversitesi;EURECOM;TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;AALBORG UNIVERSITET;INOV INESC INOVACAO - INSTITUTO DE NOVAS TECNOLOGIAS;TECHNISCHE UNIVERSITAET DRESDEN";"PL;AT;UK;FI;ES;EL;FR;BE;TR;IL;DK;PT;DE";/ICT;1;0;0;1;0;0 103086;298030;Biocascade;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IEF;FP7;Biocatalytic cascades to access valuable building blocks;2013-01-15;2015-01-14;;"The aim of this project is to provide training in the multidisciplinary fields of organic chemistry, biocatalysis, molecular biology, biochemistry and microbiology to design and develop artificial cascades by combining various types of enzymes such as L-amino acid oxidades, alcohol dehydrogenases and lyases. This is a truly competitive, innovative and timely field in which to work, and for sure the results derived from this cutting-edge project will be published in top ranked journals contributing to European Excellence. The project is expected to make a major contribution to replace traditional chemical manufacturing which relies in highly toxic, expensive and stoichiometric reagents, many steps and toxic solvents with so-called “white biotechnology” which employs powerful natural biocatalysts such as enzymes or whole cell microorganisms that allow the combination of several steps in one-pot without isolation of intermediates (cascade reactions) establishing environmentally benign and sustainable chemical processes for the preparation of optically active valuable compounds and minimizing the wastes. The research project will be divided in three main research objectives: (i) Enzymatic cascades leading to aminoacids to hydroxyacids: Novel enantioselective routes for the preparation of enantiopure hydroxyacids, (ii) Biocatalytic cascades leading to trans-coumaric acid derivatives, (iii) Redox-neutral cascade coupling of lactate to phenol via C-C bond formation. Applications to natural product synthesis. The optimal development of the project is guaranteed by the high quality of the host institution (University of Graz) and the supervisor (Prof. Wolfgang Kroutil). The host institution owns all the facilities and infrastructures that are required for the performance of this interdisciplinary project while Prof. Kroutil is a world-leading scientific in the field of biocatalytic cascade transformations with well established collaborations with world-class researchers.";187888,2;187888,2;FP7-PEOPLE-2011-IEF;/MC-IEF;UNIVERSITAET GRAZ;AT;;;/SCI;1;0;0;1;0;0 90210;239268;LEGISLATIVE SPEECH;ONG;FP7-PEOPLE;PEOPLE-2007-4-3.IRG;FP7;The Institutional Foundations of Legislative Speech;2009-04-01;2012-03-31;;This project will examine how partisan and electoral institutions influence parliamentary debates. Despite its importance in the democratic process, parliamentary debate has received less attention than voting, the other primary form of legislative activity. While elections in the EU and in member states increasingly demonstrate voters' disenchantment with politics, it is unknown how various communication channels between politicians and voters actually work. This includes parliamentary debates as the most visible of these channels. The project will draw upon institutional theories of legislative politics to study the strategic nature of political communication and collect new data on legislative debate participation and content in national parliaments (Germany and the UK) and in the European Parliament. In addition, it will employ novel quantitative text-analytic methods to evaluate the data and build upon the methodological arsenal developed in computational linguistics in order to estimate legislators' positions from speeches. This project aims at generating new insights into the institutional foundations of democratic debate participation and content in parliaments, expanding the scope of the questions explored in previous studies on parliamentary deliberation and comparative institutional analysis of legislatures, and at establishing interdisciplinary linkages between political science and computational linguistics. In addition, this project will lead to new research tools for the analysis of political speech.;75000;75000;FP7-PEOPLE-IRG-2008;/MC-IRG;UNIVERSITAET MANNHEIM;DE;;;"/SCI;/COO";1;0;0;1;0;0 102759;284369;ICAD;ONG;FP7-IDEAS-ERC;ERC-SG-SH3;FP7;Advancing Knowledge Systems to Inform Climate Adaptation Decisions;2012-04-01;2017-03-31;;"Adaptation to climate variability and change represents an important challenge for the sustainable development of society. Informing climate-related decisions will require new kinds of information and new ways of thinking and learning to function effectively in a changing climate. Adaptation research requires integration across disciplines and across research methodologies. Currently, we lack the critical understanding of which kinds of knowledge systems can most effectively harness science and technology for long-term sustainable adaptation. This interdisciplinary research programme aims to significantly advance knowledge systems to enable society to adapt effectively to an uncertain climate. The programme is divided into two domains: 1) Understanding climate information needs across society and 2) The social status of techno-scientific knowledge in adaptation to climate change. The whole programme will be applied to the UK context given the sophistication of existing knowledge systems (such as probabilistic climate scenarios) and the progressive climate policy landscape (that requires public authorities to regularly report on adaptation activities). The first objective will be achieved through a targeted comprehensive survey of user needs across UK society. After mapping a selection of diverse adapting organisations, in-depth interviews will be conducted with 70 organisations. The interview protocol will: 1) explore the adaptation context; 2) assess the credibility, legitimacy and saliency of climatic and non-climatic knowledge systems; 3) assess the impact of uncertainty on decision-making; and 4) assess users expectations of what science can deliver. The second domain will use science studies to examine the construction, mutation and use of techno-scientific knowledge in adaptation to climate change. Ethnographic research will be conducted through in-depth interviews with 50 experts working on the UK Climate Projections 09 and the Climate Change Risk Assessment.";1045000;1045000;ERC-2011-StG_20101124;/ERC-SG;UNIVERSITY OF LEEDS;UK;;;/SOC;1;0;0;1;0;0 94110;249416;RELMIN;ONG;FP7-IDEAS-ERC;ERC-AG-SH6;FP7;The legal status of religious minorities in the Euro-mediterranean world (5th-16th centuries);2010-03-01;2015-06-30;;European religious diversity has its roots in the practice of medieval societies. Medieval European polities, Christian and Muslim, granted protected and inferior status to selected religious minorities. RELMIN will collect, publish and study legal texts defining the status of religious minorities in pre-modern Europe. The corpus of texts includes Roman law (in particular in the legal codes of Theodosius and Justinian), canon law (acta of Church councils, the Decretum attributed to Gratian, the Decretales), national or royal law (from barbarian law codes of the early Middle Ages to national compilations such as the Siete Partidas of Alfonso X of Castile in the thirteenth century), urban law (particularly the fueros in the Iberian peninsula and hisba manuals in Andalusia), rabbinical responsa, and fatwa collections. The database will contain texts in their original languages and translations into English, French and Spanish, as well as an annotated bibliography on the subject. This will become a major reference tool for research in the history of minority law and of interreligious relations. The project will also hold workshops and a major international conference on Religious diversity in pre-modern Europe. A series of comparative thematic studies on specific aspects of interreligious relations will allow us to compare responses to similar issues in diverse societies, from seventh-century Córdoba to fifteenth-century Krakow. The goal is to encourage collaborative interdisciplinary work by scholars from different countries with varying linguistic skills, to encourage new innovative research that cuts across traditional divides. The project will publish three major works in the field: the proceedings of the international conference, a sourcebook of selected legal texts (with translations, commentaries and annotated bibliography), and a monograph on the legal status of minorities in pre-modern Europe.;2305000;2305000;ERC-2009-AdG;/ERC-AG;Maison des Sciences de l'Homme Ange-Guépin;FR;;;/SOC;1;0;0;1;0;0 98100;276781;QNDLattice;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-RG;FP7;Quantum control: manipulating and interfacing selected atoms in optical lattices with light;2011-03-01;2014-02-28;;"'The interdisciplinary boundary between the fields of quantum information science, condensed matter, and ultra-cold atomic physics is at the heart of the new field of quantum engineering and will play an important role for the enhancement of our understanding of strongly correlated materials. One of the most important tools in this domain is optical lattices, which are periodic optical potentials – artificial 'crystals' - created by counter-propagating laser beams. The dynamics of ultra-cold atoms in optical lattices is very similar to that found in solid state systems. In contrast to these, however, optical lattices have a high degree of purity, regularity, and tunability. They are therefore an ideal test bed for many condensed matter models such as those relevant for high-Tc-superconductivity and are a strong candidate for scalable quantum computation. The proposal will address two fundamental issues. Challenge 1: interface ultra-cold atoms in optical lattices with light. Although a non-destructive probe of the states in optical lattices would have great implications for the investigation of the rich many-body dynamics as well as for the field of quantum information processing it has never been implemented. In this project the experience of the applicant in non-destructive probing of room-temperature atomic gasses will be extended to optical lattices. Challenge 2: the manipulation and detection of single sites in an optical lattice represents a formidable technical challenge since the lattice spacing is of the order of 0.5um. In two hallmark experiments this resolution was achieved optically recently but the approach is very expensive and technically involved. Within this proposal a new way of achieving this resolution is introduced based on the interference of multiple coherent beams. Apart from technical simplicity it also offers enhanced sensitivity since the manipulation is controlled via the frequency – one of the most well-controlled properties in physics.'";45000;45000;FP7-PEOPLE-2010-RG;/MC-ERG;AARHUS UNIVERSITET;DK;;;/SCI;1;0;0;1;0;0 105097;299616;Cultural Encounters;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IIF;FP7;Cross-cultural Encounters – the Travels of Gender Theory and Practice to China and the Nordic Countries;2013-04-01;2015-03-31;;"This interdisciplinary project is concerned with the cross-cultural translation of knowledge and practices that may take place when different cultures interact, and the resulting production of new knowledge. Taking the travelling routes of gender theory and practice to China and the Nordic countries as the empirical object of study, the project will focus on the crucial questions of why and how knowledge travels or fails to travel. The project will explore in which forms and by whom knowledge is sent, received, understood, translated, or even rejected as well as the impact of these travels. The main objective is to develop an alternative travelling theory to facilitate an improved understanding of the cross-cultural translation of knowledge and practices. The project is significant for the European Research Area, as well as for governments, civil society and the general public in light of increased and new forms of cross-cultural interaction between Europe and Asia.";318514,6;318514,6;FP7-PEOPLE-2011-IIF;/MC-IIF;KOBENHAVNS UNIVERSITET;DK;;;/SCI;1;0;0;1;0;0 99154;274454;FiMaGP;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-IEF;FP7;Financial Markets and Regulation: A Genetic Programming Approach;2011-06-01;2012-09-30;;"This project contributes to the understanding of the impact of financial regulation on securities markets through the development and application of an interdisciplinary approach which combines finance, economics and computer science to study order book and OTC markets. Our research supports regulators in forecasting and quantifying the effect of regulations. The insights gained in this project are highly relevant for policy makers as European competitiveness and growth can be negatively affected if regulations are poorly designed. Despite a dearth of scientific insight into the effects of regulatory measures, short sale bans and financial transactions taxes to curb `speculation’ have strong political support in Europe. On the market design side, OTC markets, whose lack of transparency is believed to have deepened the financial crisis, are under scrutiny with the aim to centralise trade. We study microstructure models where investors and security traders submit orders or write contracts to adjust their asset holdings over time. Trader behaviour is represented by computer programmes which process information. We identify behavioural equilibria through genetic programming which exerts evolutionary pressure to successively improve the traders' decision-making abilities until abnormal returns are eliminated. In these equilibria of behaviour and market dynamics, traders are optimally adapted to the institutional and regulatory setting. Results are obtained on the impact of regulatory measures on market stability (excess volatility and crashes), microstructure properties (market quality, price discovery) and the behaviour of investors and traders (asset allocation, skills) which are highly relevant to the understanding and prevention of market breakdowns and financial crises. The models and results will be published as a book to promote this newly established field. We will make the software available as open source code to ensure verifiability of the results.";190306,67;190306,67;FP7-PEOPLE-2010-IEF;/MC-IEF;NORGES HANDELSHOYSKOLE;NO;;;"/EMP;/EDU;/NET";1;0;0;1;0;0 98501;274135;PARIM;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-IIF;FP7;Polygermane Block Copolymers: Synthesis, Self-Assembly, and Applications in Nanotechnology;2011-03-01;2013-02-28;;"Polygermanes, polymers with a -GeR2- repeat unit, are a potentially useful class of inorganic polymers with exciting chemical, physical, and electronic properties. Although recognized for having much promise, the study of polygermanes has been severely hindered by inadequate synthetic routes. In this proposal we target the creation of novel organogermanes as precursors for use in living anionic polymerizations. The realization of living polygermanes will allow for their incorporation into block copolymers such that self-assembled germanium containing nanostructures can ultimately be achieved. Potential nanotechnological applications are envisioned in nanolithography, photonics, and nanoelectronics. The applicant’s experience in synthetic germanium chemistry, combined with the host’s expertise in polymer and materials science, will be key to the proposal’s success. The project is both interdisciplinary and multidisciplinary and includes aspects of organometallic chemistry, polymer chemistry, materials science, and nanotechnology. The project will utilize the host’s existing international collaborations and will also establish new partnerships. The proposal will significantly enhance Europe’s position in the fields of nanotechnology and materials science, an important goal of the FP7. At the end of the fellowship the applicant aims to return to his home country to take up an academic position at a top university.";210092,8;210092,8;FP7-PEOPLE-2010-IIF;/MC-IIF;UNIVERSITY OF BRISTOL;UK;;;"/SOC;/COO";1;0;0;1;0;0 98232;272176;supraNANOASSEMBLY;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-IEF;FP7;Complex Supramolecular Architectures via the Micellization of Semicrystalline-Coil Block Copolymers: Synthesis and Hierarchical Self-Assembly;2011-04-01;2013-03-31;;"The development of nanostructured soft materials based on the solution self-assembly of polymers is an area of intense global interest. The self-assembly of semicrystalline-coil block copolymers is virtually unexplored but offers new opportunities to prepare well-defined micelles and enhances the opportunities to fabricate and manipulate novel nanostructures with tailored properties. This represents an important challenge for the successful exploitation of their potential for future technological applications ranging from stimuli-responsive nanoscaffolds to composite materials with improved functional characteristics. Recent advances in processing approaches using crystalline-coil systems with metalloblocks have provided new levels of tailorability to the self-assembled structures formed by block copolymer assemblies in solution. The generalization of this approach to other materials renders feasible the precise bottom-up formation of a broad range of unique functional nanostructures. As a result of the distinctive physical properties and functions of the constitutional components, diblock copolymers containing crystalline stereocomplexed polylactide or polycaprolactone segments will be studied as they provide an exciting opportunity to access novel hierarchically structured polymeric nanoobjects with predetermined properties. This interdisciplinary and multidisciplinary research proposal requires a wide range of skills and combines the expertise of the applicant (polymer synthesis and self-assembly in the solid state) with that of the host laboratory (polymer chemistry, block polymer self-assembly in solution, materials chemistry, and nanoscience). The proposed fellowship will bring a promising young researcher to the UK for 2 years to be followed his return, preferably to Greece, or relocation elsewhere in the EU.";272636,8;272636,8;FP7-PEOPLE-2010-IEF;/MC-IEF;UNIVERSITY OF BRISTOL;UK;;;"/EMP;/EDU;/NET";1;0;0;1;0;0 95784;252743;JBGIM;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IIF;FP7;Functional Nanoscale Coordination Polymers: Controlled Growth by Metal-Containing Block Copolymer Templated Self-Assembly;2010-07-12;2012-07-11;;Coordination polymers are infinite arrays of bridging ligands bound to two or more transition metal ions. The potential application of coordination polymers in the areas of materials and nanoscience is significant as their properties can be tuned through variation of the transition metal ions and bridging ligands. To date, research in the area of functional nanoscale coordination polymers has been limited to amorphous (spherical) and crystalline (non-spherical) examples and the controlled growth of coordination polymers has not been realized. We propose the use of metal-containing diblock copolymer templates, which self-assemble in a number of different morphologies depending on the volume fraction of the blocks, to influence the structure of coordination polymers on the nanoscale, and for the first time demonstrate control over their size and shape. Our approaches will afford multifunctional materials with highly tunable properties, and the incorporation of diblock copolymers will allow for the rational design and controlled growth of nanoscale coordination polymers. This highly interdisciplinary and multidisciplinary research proposal requires a wide range of skills and this is exactly the mix possessed by the applicant (ligand design, coordination chemistry, stable-radical chemistry, electrochemistry, and molecule-based magnetism) and the host laboratory (polymer chemistry, materials chemistry, and nanoscience). The proposed research will bring a promising young researcher to Europe, and will lead to a new area of functional polymer and materials research where a range of potential applications are envisioned.;173240,8;173240,8;FP7-PEOPLE-2009-IIF;/MC-IIF;UNIVERSITY OF BRISTOL;UK;;;"/SCI;/EDU;/ITT";1;0;0;1;0;0 91979;237133;DOUBTANDITSNAMES;ONG;FP7-PEOPLE;FP7-PEOPLE-IOF-2008;FP7;Doubt and Its Names;2009-10-01;2012-09-30;;This project deals with a root of Western culture: doubt. Its chief aim is produce a history of Renaissance doubt by comparing the professional philosophers’ treatment of doubt to a wider range of contemporary sceptical attitudes. It will single out a select group of concepts of sceptical interest – such as doubt, uncertainty, conjecture, and so on – from well-known Renaissance sources that belong to an eminently ‘conjectural’ discipline such as philology, or more precisely textual criticism. The proposed research aims at identifying the sceptical elements within philology by shedding new light on humanist editorial practices (e.g., critical apparatus, running commentaries, etc.). It will focus on the exact conditions which led outstanding Renaissance philologists such as Angelo Poliziano and Erasmus of Rotterdam, Lorenzo Valla and Beatus Rhenanus, to name only a few, to suspend judgment about a controversial text. This project embraces a strongly interdisciplinary method. Besides textual criticism, it will explore doubt in other non-philosophical domains, such as medicine, law, and history, in order to point out both theoretical connections and historical interactions between these disciplines, and map out doubt and its names in the early modern period. The concrete aim of the project is to produce a monograph entitled ‘Doubt and its names’.;326565,05;326565,05;FP7-PEOPLE-IOF-2008;/MC-IOF;UNIVERSITY OF LONDON;UK;;;"/COO;/EDU";1;0;0;1;0;0 87423;210867;SEEDS OF LIFE;ONG;FP7-IDEAS-ERC;ERC-SG-LS1;FP7;Seeds of life - analysis of seed growth and development;2008-07-01;2013-06-30;;Flowering plants have evolved as one predominant life form on earth. One common principle of flowering plants and probably one of the main reasons for this evolutionary success is the rapid development of an embryo along with a nourishing tissue, called the endosperm. Embryo and endosperm are surrounded by maternal tissues and build the plant seed. Seeds are a fascinating biological structure and their formation is an essential step in the plant life cycle. Seeds also represent the major food source for animals and humans and for this reason, are an indispensable unit in the ecosystem on earth. Despite its importance, surprisingly little is known about seed growth and further progress for the understanding of seed development appears to be hampered by three major constraints. First, seeds are compound structures comprising different tissues of different origins. For proper development, however, a close coordination between these structures is required. Second, the involved organs and tissues are deeply buried within maternal tissues and thus, they are not easily accessible. Third, the parent of origin for certain regulators appears to be crucial for their expression in the seed and an understanding of the complex chromatin regulation that mediates these gene activity patterns is still at its beginning. Here an interdisciplinary and multi-species project is proposed to overcome these constraints unraveling the molecular mechanism and principles of seed growth control. By analyzing seed development in two distantly related species with a combination of cell biology, biochemistry as well as molecular biology including quantitative genetics and genomics, I will obtain detailed insights into one of the central processes of (plant) life.;1300000;1300000;ERC-2007-StG;/ERC-SG;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FR;;;"/BIO;/LIF";1;0;0;1;0;0 87477;207916;FEMTOSCOPY;ONG;FP7-IDEAS-ERC;ERC-SG-PE3;FP7;Femtosecond Raman Spectroscopy: ultrafast transformations in physics, chemistry and biology;2008-09-01;2013-08-31;;We propose the construction and development of a femtosecond broadband stimulated Raman setup to tackle ultra fast chemical, physical and biological processes taking advantage of the top-notch structural sensitivity inherent to the Raman process. The use of a pump-probe stimulated scheme will allow to overcome time-energy restrictions dictated by the uncertainty principle, enabling to reach the femtosecond timescale with energy resolutions which would pertain to the picosecond time domain in the Heisenberg sense. Protein dynamics span several orders of magnitude extending up to macroscopic timescales, the recipes to tailor properties of rubbers and polymers relevant for human timescales are covered by more than 500000 patents, rust reaction occurs over several days, and lethal brain strokes often lead to death within 24 hours on average. The lowest hierarchical level of such processes, however, is hidden in the very act of atomic motion and chemical binding such as the single bond dynamics in a peptide backbone, the monomer cross-linking elemental reactions, the energy flow and re-distribution in a hydrogen bond network, or the oxygen binding to heme proteins, all performing on the femtosecond stage. Mastering these processes is the essence of femtochemistry, born around the backbone of the femtosecond laser technology and boosted by scientific activity which led to the Nobel prize of Prof. A. Zewail in 1999. The new capabilities offered by femtosecond sources have often left behind in the race traditional spectroscopies, which hardly follow the growing emergence of new challenging problems in which the traditional distinction between biology, chemistry and physics is smeared out by the common ultra short timescale. The set up of a non conventional femtosecond Raman technique will be the initiating event for the establishment of a research group of interdisciplinary nature toiling over unsolved problems in which the ultrafast facet plays a key role.;1544400;1544400;ERC-2007-StG;/ERC-SG;UNIVERSITA DEGLI STUDI DI ROMA LA SAPIENZA;IT;;;"/PSE;/ELM;/NNT";1;0;0;1;0;0 107303;331800;INTERACTIONS;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IEF;FP7;"""Investigation of the interaction between external stimulation and ongoing brain activity in cortical networks: analysis, modeling and empirical corroboration""";2013-04-15;2015-04-14;;"'The study of brain connectivity is a very important and productive subfield of neuroscience that will keep growing in the following years. Large efforts of data analysis from EEG and fMRI data, as well as of modelling brain activity have been accomplished recently. Here, we have identified two fundamental problems that the field is facing in order to develop further. First, a common factor in the current models of cortical networks is their lack of external stimulation, i.e. they only simulate cortical activity that emulates the resting-state. But the brain is responsible for collecting and processing information of the environment, and therefore, its function cannot be understood in the absence of external stimuli. Second, current EEG and fMRI techniques provide an extremely valuable window into the working brain by detecting the degree of activation of brain regions. However, there is currently no framework to understand which are the precise information processes happening at the neuronal level behind the observed activations. Inspired by these questions, we present an interdisciplinary project that aims at establishing grounding work for the future advances in those problems: 1) We will perform a systematic investigation of the impact of external stimulation in models of cortical networks. The dependence of the emerging collective dynamical phenomena will be studied in terms of the network topology and of the physical properties of the stimuli. 2) We will develop information theoretical measures to quantify the degrees of segregation and integration caused in the brain by the presence of external stimulation, and 3) we will apply those measures to specifically designed EEG experiments for corroboration.'";166336,2;166336,2;FP7-PEOPLE-2012-IEF;/MC-IEF;UNIVERSIDAD POMPEU FABRA;ES;;;/SCI;1;0;0;1;0;0 96439;254277;UNCOVER;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IEF;FP7;Understanding Collaboration in 3D Virtual Environments;2010-12-01;2012-11-30;;The proposed research aims to advance our understanding of virtual teamwork in 3D collaborative virtual environments (CVE) that have gained increasing importance in global organizations and higher education institutions, and are subject to an emerging interdisciplinary field of research. CVE have been developed to facilitate cross-border collaboration and to overcome the issues associated with traditional collaboration tools. Team members are embodied as avatars, communicate via chat and audio channels, and can jointly look at and manipulate objects in a shared virtual space. However, it is still unclear whether the findings obtained in traditional small group research and earlier virtual team studies can be applied to embodied collaboration in CVE. Our goal is to investigate group interaction processes and outcomes in physical and virtual environments in order to examine how different media affect group behavior and under what conditions which medium is most effective. We use a mixed-method approach combining behavioral observation and self-report data, and develop an innovative methodology that makes it possible to automatically and unobtrusively collect data on group behavior in CVE interactions. The proposed research integrates findings from a large-scale international field study and experimental laboratory studies. While the field study focuses on cross-cultural aspects of collaboration in CVE, observation of long-term group interactions and project work, the experimental studies are designed as a media comparison using different task types and short-term observation of ad-hoc groups. Several interrelated research objectives are formulated for a systematical investigation of behavioral patterns and psychological effects that emerge from group interactions in virtual and physical environments. The fellowship would be undertaken at the IDC Herzliya in Israel as it provides the ideal environment for the applicant to meet her research and training objectives.;174653;174653;FP7-PEOPLE-2009-IEF;/MC-IEF;INTERDISCIPLINARY CENTER (IDC) HERZLIYA;IL;;;"/SCI;/EDU;/ITT";1;0;0;1;0;0 106361;316906;LUMINET;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-ITN;FP7;European Network on Luminescent Materials;2012-12-01;2016-11-30;;Luminescent materials have entered our every day life. They can be found in lamps, traffic lights, computer screens, cell phones, in labels for goods, are used in medical applications, airport security check devices and many more. Indeed, they have become indispensable and much of societies convenience and welfare depend on them. No wonder that the development and use of luminescent materials has truly exploded in the past decade stimulated by the challenging requirements of technological applications spanning domains from solid-state lighting, optics and photonics, energy conversion and storage to well as labelling, detection and imaging in biomedicine. The production of luminescent materials and related devices also is the basis for a large industrial sector with the most key stake holders situated in Europe. There is and there will be a strong demand for skilled scientists in the area of luminescent materials which demands the definition of a precise human resource policy to attract young and highly motivated students that can be well qualified to address the exigent technological requirements of the field and help to strengthen the European technology and research area and allow European companies to keep their status as world market leaders. At the same time sustainable employment opportunities can be guaranteed with high quality jobs. To address theses topics, LUMINET intends, through a rigorous training programme, to strategically position the EU with respect to new and improved possibilities and educated young scientists. It aims at educating a number of well-educated and talented young researchers with a broad, interdisciplinary knowledge in chemistry, physics, materials science and engineering but also in soft-skills like problem-solving and project management that are able to meet the challenges of the future.;3639845,23;3639845,23;FP7-PEOPLE-2012-ITN;/MC-ITN;UNIWERSYTET WROCLAWSKI;PL;"UNIVERSITA DEGLI STUDI DI VERONA;TARTU ULIKOOL;UNIVERSITAT DE VALENCIA;UNIVERSITAET BERN;OSRAM GMBH;FYZIKALNI USTAV AV CR V.V.I;UNIVERSIDADE DE AVEIRO;RUHR-UNIVERSITAET BOCHUM;PHILIPS ELECTRONICS NEDERLAND B.V.;UNIVERSITEIT UTRECHT;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS";"IT;EE;ES;CH;DE;CZ;PT;NL;FR";/LIF;1;0;0;1;0;0 104566;301541;Urban Inequality;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IOF;FP7;Planning in Equality? Urban Strategy and Inequality in Global South Cities;2012-09-01;2015-02-28;;"The rapid urbanization in the Global South is one of the greatest challenges of the 21st century, taking place through highly unequal and largely informal development. In this context, various “urban strategies” are promoted to “harness urbanization to deliver equitable and inclusive growth”. However, there is insufficient knowledge to date on the adeptness of such strategies and other “strategic plans” and “visions” to address the challenges of urban inequality in a way that corresponds to local conditions and lived experiences in Global South cities. To fill this lacuna, the project will examine how concepts of urban inequality – theories, methodologies and “best practices” regarding socio-spatial disparities in cities, their consequences, and ways to tackle them – are formulated, mediated and negotiated through urban strategic processes. The research will offer: (1) a cross-national comparison of strategies, highlighting their spatial imaginary and “visual politics” vis-?-vis inequality; (2) an in-depth analysis of the urban strategy process in one Global South city (potentially Mumbai/Delhi or Cape Town/Johannesburg). It will follow both grassroots and grasstops processes through which diverse concepts, values and visions relating to inequality shape urban strategy, at several levels: the international development organization, national and local government, business elites, NGOs, middle-class and marginalized urban communities. It will consist of a multi-method ethnography, including interviews with key stakeholders, participant observation, analysis of plans and policy documents, and innovative visual methods. Based at the interdisciplinary Center for Global Metropolitan Studies at Berkeley and the Center for Urban and Regional Studies at the Technion, with further mobility to the Global South, the project will strengthen research networks and make a substantial contribution in the fields of planning, urban sociology and critical development studies.";228311,55;228311,55;FP7-PEOPLE-2011-IOF;/MC-IOF;TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY;IL;;;/SCI;1;0;0;1;0;0 95973;252191;CERAMEM;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IEF;FP7;Novel tailored ceramic membranes for water treatment applications;2010-09-15;2012-09-14;;This project addresses an acute and relevant worldwide problem: The scarcity of fresh water. The current solutions to this problem are based on desalination of sea water and on wastewater treatment. In both cases, the state-of-the-art uses reverse-osmosis membrane technology, that employs polymer membranes. The problem is that these membranes are sensitive to fouling and degradation, and although they are relatively inexpensive their frequent replacement is costly and labor-intensive. Here we propose using a new type of hybrid ceramic membranes, developed in our group, as pre-treatment filters (ultrafiltration) in the purification process. Ultimately, we also envisage a one-stage reverse osmosis water purification process using only the hybrid ceramic membranes. These novel membranes are extremely stable, and are easily tailored to specific applications. The project will boost the career of the applicant, Dr. Vitaly Gitis. He will be trained in the synthesis of these new hybrid materials, enabling him to transfer the knowledge to his home university and apply it in his research group. Combined with his considerable experience of water purification processes, the new knowledge will give him a ‘research edge’ that will make him a leader in the field. Moreover, the additional ‘soft skills’ training that he will receive, plus the international and interdisciplinary experience, will cement his position in his home country. Finally, the host institution will also benefit substantially from the project, as the applicant will transfer his own knowledge and experience to the hosting group and to the institute.;225385,6;225385,6;FP7-PEOPLE-2009-IEF;/MC-IEF;UNIVERSITEIT VAN AMSTERDAM;NL;;;"/SCI;/EDU;/ITT";1;0;0;1;0;0 102698;303507;OPRA;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-CIG;FP7;OPTIMALITY PRINCIPLES IN RESPONSES TO ANTIBIOTICS;2013-02-01;2017-01-31;;"Antibiotics kill bacteria or inhibit their growth by targeting essential cellular processes. In response to antibiotic exposure, bacteria activate gene regulation programs that are specific to the action of the antibiotic. These responses to individual antibiotics are often well-mapped, but how do bacteria respond dynamically to drugs? And is this regulation optimized for survival and growth in the presence of the drugs? We propose an interdisciplinary experimental-theoretical approach to measure, model, and synthetically manipulate the regulatory response to antibiotics. Specifically, we will (1) use an automated robotic system, an Escherichia coli library of fluorescent transcriptional reporters, and RNA-seq to measure changes in growth, physiology, and global gene expression in response to antibiotics; (2) develop theoretical models of gene regulation and predict ‘re-wirings’ of the gene regulation network that would worsen or improve growth and survival under antibiotic stress; (3) use a synthetic biology approach to test these predictions and to quantify the extent of optimization in bacterial gene regulation. We will develop this approach using the powerful model system Escherichia coli and then apply our key findings to Staphylococcus aureus, a clinically more relevant pathogen. Our work will lead to the first quantitative genome-wide characterization of the extent to which microbial stress responses are optimized for responding to drugs. We anticipate that this knowledge can be exploited to improve drug treatments. The systematic fundamental research proposed here will reveal exploitable weaknesses in cellular responses to drugs. It will thus contribute to the alleviation of one of the most serious public health concerns of our time: the rapid spread of drug-resistant bacterial pathogens, including methicillin-resistant S. aureus (MRSA), which coincides with a dramatic decline in the rate at which new efficient antibiotics are discovered.";100000;100000;FP7-PEOPLE-2011-CIG;/MC-CIG;Institute of Science and Technology Austria;AT;;;/SCI;1;0;0;1;0;0 96526;255577;V-STIR;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IIF;FP7;Visual-spatiotemporal integration for recognition;2010-11-01;2012-10-31;;Detecting and identifying targets in cluttered scenes is critical for successful interactions in the complex and dynamic environments we inhabit. Despite the ease and speed with which we recognize objects, visual recognition entails the computationally challenging task of binding relevant features together for the perception of coherent meaningful objects. Most work on visual integration focuses on spatial binding processes. However, detecting dynamic objects in cluttered scenes entails storage of image fragments in memory and integration across time. Here we propose to investigate the mechanisms that mediate integration across space and time. We will exploit the contour slit-viewing paradigm: that is, an object moving behind a narrow slit is still perceived as a whole. In task 1, we will characterize quantitatively the ability for slit-viewing perception and generate a computational model describing the principles that guide spatiotemporal integration. In task 2, we will test for similarities and differences in the neural substrates underlying spatial and spatiotemporal integration using conventional GLM and advanced multivariate analyses. In task 3, we will test for cortical regions that mediate perceptual deformations under slit-viewing. Task 4 will use precise retinotopic mapping to investigate the memory store processes engaged in spatiotemporal integration. Finally, in task 5 we will employ simultaneous EEG-fMRI recordings to examine the dynamic information processing of spatiotemporal integration and the interactions within the cortical circuit involved. The proposed work programme will devise a new paradigm and take advantage of recent advances in multimodal recordings (EEG-fMRI) and advanced computational analysis methods to explore the neural mechanisms of spatiotemporal integration for the first time. This interdisciplinary work will offer new insights into the neural machinery that underlies our ability to recognize dynamic objects in cluttered scenes.;181103,2;181103,2;FP7-PEOPLE-2009-IIF;/MC-IIF;THE UNIVERSITY OF BIRMINGHAM;UK;;;"/SCI;/EDU;/ITT";1;0;0;1;0;0 96266;252756;ANCID;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IEF;FP7;The role of animals in late Iron Age and Roman life: cultural identity and the relationship between Italy and Britain;2010-10-01;2012-09-30;;Archaeological evidence has indicated that major cultural changes occurred in Europe between the Late Iron Age and Early Roman periods, although these were neither homogeneous nor universal. The theoretical framework by which to interpret these complex processes has been energetically debated and remains contentious. Animal bones recovered from archaeological habitation sites - mostly the product of meal, kitchen and waste - can reveal far more than merely the diet of past societies. They reflect a complex web of economic, social, religious, political and domestic circumstances and behaviours and can help our understanding of the cultural identity of past human communities. The project is designed to develop a much-needed scientific approach to the study of animal assemblages found in Italy and Britain and dated to the pre- and Roman periods. Questions, such as change and/or improvement of husbandry techniques, contribution of local breeding, introduction of livestock, use of land, role of market, influence of local culture and permanence of the Iron Age ideology will be investigated. The project will build on previous work carried out at a national level, but will try to provide a pan-European perspective by comparing the evidence from the origin of Roman influence - Italy – with that of one of the colonies – Britain. The project will be interdisciplinary as it will benefit from several methodological approaches, including taxonomy, demography, biometry and biochemistry. A key research aim will be to identify changes in bone size and morphology and mortality patterns, and to interpret any observed trends in terms of factors such as site type, location and chronology. It will incorporate analyses of newly collected data and that from sites which have been previously published to a high standard. Cattle tooth enamel from selected sites will be subjected to strontium and oxygen isotopic analysis to investigate the relative diversity/homogeneity of livestock supply.;240289,6;240289,6;FP7-PEOPLE-2009-IEF;/MC-IEF;THE UNIVERSITY OF SHEFFIELD;UK;;;"/SCI;/EDU;/ITT";1;0;0;1;0;0 95955;250589;PASSAROLA;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IEF;FP7;Statistical and dynamical analysis of collective behaviour in a three-dimensional motion: Empirical studies and modelling;2010-11-01;2012-10-31;;Collective behaviour is ubiquitous in living systems such as flocks of birds, swarms of insects or schools of fishes. It occurs for several reasons which go from predator protection to mating. To better understand those living systems it is therefore important to understand how collective behaviour emerges and its features. For large flocks of birds and swarms of insects little work has been made from the perspective of empirical and statistical analysis towards modelling of different types. This proposal aims to make a comprehensive data acquisition of three-dimensional data of position and trajectories of elements in groups of flying animals for posterior statistical, dynamical and non-linear analysis characterisation and consequent modelling. It corresponds to the first broad approach to collective phenomena starting from measuring real features in order to reproduce them. After this study it will be possible to understand to fundamental principles of aggregation of birds and some species of insects and to appraise whether those mechanisms are common in flocking and swarming. To that, a interdisciplinary approach involving the fields of Biology (Animal Behaviour),;166239,4;166239,4;FP7-PEOPLE-2009-IEF;/MC-IEF;CONSIGLIO NAZIONALE DELLE RICERCHE;IT;;;"/SCI;/EDU;/ITT";1;0;0;1;0;0 102978;303972;CELLMECH;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-CIG;FP7;Molecular-Physical Basis of Cell-Biomaterial Mechanical Coupling;2012-04-01;2016-03-31;;"I seek to understand the molecular origin of cell mechanosensing - the ability of biological cells to sense and respond to the mechanical properties of their environment. Moreover, I want to explore the possibility that propagation of mechanical deformation within soft biomaterials can act as a communication route between neighboring cells. A long term goal is to guide injured axons to establish reconnection with the proper target by directing the axon towards the mechanical deformations generated by the target cell. ‘Cell mechanosensing’ raises some basic science questions, part of which can only be solved by an interdisciplinary-multi-scale approach, combining concepts from macroscopic approaches - such as elasticity theory and rheology - with a molecular point of view, taking into account the intricate interplay of chemical and physical processes. We will use a unique combination of high resolution optical microscopy, single molecule imaging, magnetic tweezers, biomaterial design and characterization, numerical algorithms and theoretical modeling. In particular, our aims include: 1. Characterization of the force generated by neuronal growth cone and its frequency, before and following injury. 2.Developing new engineered protein biomaterials with mechano-sensitive properties and a well defined dynamic viscoelastic profile which are able to support neuronal cell growth. These include biomaterials which: a) Change their fluorescence properties in response to small material deformations in the nanometer range. b) Efficiently propagate and amplify growth-cone-generated mechanical deformations to allow for cell-cell communication. An essential part of this project is studying the dependence of the viscoelastic spectrum of the network on the mechanical properties of the single chain. 3. Identifying the feedback mechanism that enables the cell to regulate its intrinsic elasticity and the forces it applies in response to the mechanical properties of the substrate.";100000;100000;FP7-PEOPLE-2011-CIG;/MC-CIG;TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY;IL;;;/SCI;1;0;0;1;0;0 102686;304020;CHAMP RNA HELICASE;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-CIG;FP7;Function, Mechanism, and Regulation of Mammalian Mov10L1 RNA Helicase;2012-04-01;2016-03-31;;"Adult cardiac myocytes retain the ability to respond to a variety of stimuli by hypertrophic growth. Hypertrophy is initially beneficial, permitting enhanced cardiac output; it can ultimately become deleterious and result in cardiomyopathy, heart failure, and sudden death. Mitogenic signaling drives cell cycle progression as consequences of their effects on cyclins, which interact with cyclin-dependent kinases and cyclin-dependent kinase inhibitors. Recent work showed that CHAMP has antihypertrophic activity, which requires the conserved ATPase motif that is characteristic of RNA helicase superfamilies 1 and 2, and is associated with up-regulation of the cell cycle inhibitor p21CIP1 and p27KIP1. CHAMP is localized in the cytoplasm of cardiomyocytes and is likely regulates its target RNA at the level of translation and degradation. The regulation p21CIP1 and p27KIP1 translation levels controls the proliferation of cardiomyocytes by inhibiting cell cycle progression. However, very little is known regarding the molecular mechanism of how RNA helicases regulate translation. To date detailed enzymology regarding the mechanical transduction of RNA helicases is scarcely known, especially from superfamily 1 to which CHAMP is identified with. This proposal is aim to decipher the molecular mechanism of a putative RNA helicase CHAMP and how it regulates mRNA metabolism of genes essential for the heart development during prenatal stages and regulates CDKI’s mRNA in postnatal stages. The research program will integrate state of the art molecular biochemistry and biophysics approach with medicinal translational research. An interdisciplinary structured based team will be assembled to integrate knowledge, and capacity from molecular to physiological aspects of cardio myocytes hypertrophy. This will result from integration of key enzymatic regulators as CHAMP to the physiological regulation of cardiomyocytes hypertrophy response in human at the molecular level of mRNA metabolism.";100000;100000;FP7-PEOPLE-2011-CIG;/MC-CIG;TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY;IL;;;/SCI;1;0;0;1;0;0 102585;302549;SYNTAX;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IEF;FP7;Neurophysiology of birdsong syntax perception;2012-10-01;2014-09-30;;'Like human language, birdsong is hierarchically organized according to particular syntactic constraints (phonological syntax). Interestingly, birds have also been shown to posses impressive capabilities in recognizing syntactic patterns, even artificial ones, which makes them an attractive, but as yet virtually unexplored, model for research into the neural underpinnings of syntax perception. To address this issue at the neurophysiological level, I propose to apply a high-density electrical neuroimaging technique, based on an array of intracerebral electrodes that measure action potential activity from 64 sites simultaneously, to record activity in auditory and song system nuclei during stimulation with artificial, song-like sequences. First, I will identify cortical areas that are sensitive to short term history of syllables and investigate whether the time scales at which such sensitivity is observed, matches with those necessary for syntax recognition. Second, I will test which types of short-term history sensitivity are involved. I hypothesize the involvement of both acoustic feature-specific adaptation and a distinctly different syllable-specific form of adaptation, where the former may be a causal factor in enabling the latter. Furthermore, I will test for a third form of short-term history sensitivity that has been proposed to be responsible for deviance detection as reflected in mismatch negativity (MMN) in human EEG, and that has been linked to syntactic processing of language. Together, the results may provide support for the hypothesis that phonological syntax is in part represented in activation signatures that reflect time-varying, short-term predictability of syllable occurrence within a sequence. This highly interdisciplinary project lies at the intersection of behavioural neurobiology and linguistics, and should yield an animal model system for the study of neural processes that may also underlie syntax processing in the human brain.';255069,4;255069,4;FP7-PEOPLE-2011-IEF;/MC-IEF;UNIVERSITEIT UTRECHT;NL;;;/SCI;1;0;0;1;0;0 91925;235979;RURAL DECISIONS;ONG;FP7-PEOPLE;FP7-PEOPLE-IOF-2008;FP7;Development of a framework for managing uncertain decisions in agricultural and environmental policies – Towards an integrated policy for decision-making support in rural areas;2009-06-01;2012-07-31;;Current political and scientific debates are focused on finding a long-term policy beneficial both for environment and economy in rural areas in the EU member states. The proposed research project aims to methodologically reinforce these efforts and to contribute to development of an integrated policy for decision-making support in rural areas in an interdisciplinary process. The objective of the research is to develop a methodological framework integrating uncertain economic and ecological aspects in multiobjective decision-support systems in agricultural and environmental policies for Germany, Poland, and the U.S. Several analyses have been undertaken on multicriteria decision-making approaches and the problems of uncertainty in the European Union in different disciplines. However, most of them are focused on illustrating relations between them and comparing them. With the proposed research, the existing uncertainties will be directly incorporated in decision-support systems while uncertain and fuzzy information provided by experts will be firstly operationalised by means of the PROMETHEE approach. In order to progressively evaluate political problems an integrative programming model will be constructed to integrate fuzzy information as well as game theory to consider interactive decision-making between political stakeholders. The project will provide a novel, original and sustainable scientific tool for practical implementation to improve policy evaluation and design and to alleviate interactive decision-making processes in rural areas in the European countries. Thereby, an existing scientific gap in policy evaluation and in supporting political decision-making processes in rural areas in Europe can be filled, improving European scientific competitiveness and excellence in the researched field. The fellowship will be pivotal for the scientific progress of the researcher, reaching professional maturity and for preparing for the independent scientific career.;232684,02;232684,02;FP7-PEOPLE-IOF-2008;/MC-IOF;HUMBOLDT-UNIVERSITAET ZU BERLIN;DE;;;"/COO;/EDU";1;0;0;1;0;0 105506;316379;ECHONET;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-ITN;FP7;Expanding Capability in Heterocyclic Organic Synthesis;2013-01-01;2016-12-31;;ECHONET is an Initial Training Network (ITN) comprising 8 full network participants from 6 countries, spanning 6 academic institutions and two private sector organisations, the latter representing SME and Global fine chemicals companies. The network is also supported by 2 associated partners from the private sector. Taken together, the consortium will offer research training and generic skills development by embarking on state-of-the-art chemical synthesis problems and by employing new approaches in catalysis, computational chemistry, bioactive molecule design and high throughput synthesis. As a whole, ECHONET offers tremendous opportunities for research training in an international interdisciplinary environment. It is anticipated that this network will make a significant contribution to the expertise already present in Europe, and will continue to play an important role in the progress of European fine chemical industries and related fields. ECHONET will be supported by 11 early stage researchers and 2 experienced researchers and their research training will be supplemented by formal courses and industrial experience, therefore offering valuable exposure to commercial environments.;2881334,06;2881334,06;FP7-PEOPLE-2012-ITN;/MC-ITN;THE UNIVERSITY OF SHEFFIELD;UK;"STICHTING KATHOLIEKE UNIVERSITEIT;UNIVERSITA DEGLI STUDI DI FIRENZE;BOROCHEM SAS;KARLSRUHER INSTITUT FUER TECHNOLOGIE;UNIVERSITAT DE BARCELONA;BAYER CROPSCIENCE AG;UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA";"NL;IT;FR;DE;ES";/LIF;1;0;0;1;0;0 108263;600399;SIPOD2;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-COFUND;FP7;Structural International Post Doc Program 2;2013-02-01;2018-01-31;;"The SIPOD (Structured International Post Doc Program) is designed to attract excellent scientists and to boost their career as post-doctoral fellows towards becoming successful and independent group leaders. SIPOD aims to foster the incoming trans-national mobility and the reintegration of fellows. In the proposed program the Scuola Europea di Medicina Molecolare (SEMM) operated in conjunction with three major Research Centers in Lombardy: IEO (Istituto Europeo di Oncologia), FHR (Foundation Humanitas Research) and IFOM (Istituto Firc di Oncologia Molecolare). SIPOD is characterized by: 1. Trans-national mobility and re-integration of fellows. 2. Freedom of choice for the fellows to select the research topic and destination within the receiving Host Institutions. 3. Possibility to conduct interdisciplinary research project, where fellows will have the opportunity to have joint positions on shared projects with group leaders (at least two) working in different disciplines. 3. Equal Opportunities for men and women, and consideration of career breaks. 4. Higher education program based on five training activities: Patenting, Tech transfer and Licensing; Grants scouting, writing and management; Team leading and Group organization; Translational Research and Clinical Trials; Ethical issues in science. This program stems from internal and external post-doctoral surveys indicating that at present the career transition from postdoctoral fellow to group leader (independent investigator) is not supported by an adequate training/educational support. SIPOD is designed to fill this gap. SEMM launched in 2009 its first Structured International Post doc program (SIPOD) under the FP7-PEOPLE- 2007-COFUND scheme. The success of SIPOD has prompted us to propose a new application that remains financially completely separated from the first one but that constitutes continuity for our post-doctoral program to strengthen its international recognition.";5031675;2012670;FP7-PEOPLE-2012-COFUND;/MC-COFUND;SCUOLA SUPERIORE EUROPEA DI MEDICINA MOLECOLARE;IT;;;/LIF;1;0;0;1;0;0 99405;274350;MCEUICS;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-IEF;FP7;"""Constructing Solidarities. Kinship Ties and Social Networks in the Urban Communities of Italy and the Low Countries, 1250-1550""";2011-09-01;2012-08-31;;'In the rapidly growing cities of late medieval and early modern Italy and the Low Countries new forms of trust emerged that gave social cohesion to the urban community. The new trust networks, based on the building blocks of kinship ties and extra-familial co-operation, strengthened the processes of social integration and community building in the medieval city. This project aims to reveal the social mechanisms that underlay these solidarities as well as to determine the factors that facilitated their formation. It does so by comparing the developments in cities with different political and socio-economic profiles from Italy and the Low Countries. This comparative research will enhance our knowledge about the structural factors that explain the relation between the emergence of trust networks – in particular the ruling elites and the guild organisations – and the evolution of urban communities and civil society. This approach raises methodological challenges concerning the comparison of different case studies and diverse data, which must be dealt with. The research will also contribute to the interdisciplinary debate about the practice of trust and the functioning of familial and extra-familial solidarity, drawing on sociological theory pertaining to trust and social networks. Finally, the research will add to our understanding of the bottom-up trust-building strategies of actors of various political and socio-economic backgrounds, thereby assessing the impact of more general forms of trust embodied by the medieval urban corporate and public institutions. The central question, however, is to explain how kinship ties and extra-familial social networks strengthened and facilitated the process of urban community building in Western Europe from 1250 to 1550.';91706;91706;FP7-PEOPLE-2010-IEF;/MC-IEF;EUROPEAN UNIVERSITY INSTITUTE;IT;;;"/EMP;/EDU;/NET";1;0;0;1;0;0 105928;313397;MOS;ONG;FP7-IDEAS-ERC;ERC-SG-SH5;FP7;Manifestations of Solitude: Withdrawal and Engagement in the long seventeenth-century;2013-02-01;2017-03-31;;"The objective of Manifestations of Solitude: Withdrawal and Engagement in the long seventeenth-century is to demonstrate how the creation of zones of unworldliness within the world structures re-ligious practice. We will examine withdrawal in its historical settings and uncover the facetted na-ture of this phenomenon in the seventeenth-century religious culture, thus offering insights and tools for a better understanding of the representation of religious experience in European culture. Working across cultural and confessional boundaries, the project explores appropriations of the appeal that the Christian be in the world but not of the world: in texts, architecture, images and mu-sic, and it examines the ways in which these media are employed to prompt and sustain with¬drawal from the world. The project focuses on ten institutional social units (e.g. the abbey, the Konventikel, the household), which manifest solitude in different ways. It examines such units through ten exem-plary places (e.g. Herrnhut, Saint-Cyr) and their cultural and reli¬gious life, drawing on materials such as architectural plans, interior decoration, treatises on theology and aesthetics, letters, diaries, epitaphs, emblems, portraits, devotional images, sermons and musical pieces. The backbone of the project is an innovative strategy for interdisciplinary analysis which traces the generation of a symbolically charged space around religious withdrawals. With this analytical tool we will examine how symbols of ‘world’, ‘solitude’ and the demarcation between them are materialized in forms ranging from material culture (architecture, furnishing), via artistic, perfor-mative expressions (devotional images, musical pieces) to literary topoi and metaphors and the in-fluence on such forms of contemporary aesthetic sensibilities. The project examines the cultivation of the religious self: shaping a sym¬bolically charged space – and shaped in turn by this space.";1250000;1250000;ERC-2012-StG_20111124;/ERC-SG;KOBENHAVNS UNIVERSITET;DK;;;/SOC;1;0;0;1;0;0 96042;254471;MTSBLC;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IEF;FP7;Micro-textured Surfaces for Boundary Layer Control;2010-10-04;2012-10-03;;The purpose of the proposed research is to investigate the mechanics of micro-textured surfaces, often referred to as “self- cleaning coatings”, and their influence on the incompressible fluid boundary layer as it undergoes transition from laminar to turbulent flow. Our approach combines Direct Numerical Simulation (DNS) and experimental studies, and will provide a theoretical framework for the use of micro-textured coatings in passive boundary layer control. This has broad applications in fluid mechanics from drag reduction to heat transfer enhancement to turbulent transition control. Control of these characteristics has an important role in a broad range of technologies where fluid interactions occur such as sea and air transport, power generation, electronics cooling, and microfluidic devices. Microfluidics, in particular, has been described as an enabling technology for a broad range of interdisciplinary applications including biological and chemical processes. Surface geometries that provide properties such as laminar stability which will delay the transition to turbulence, reduce turbulent shear stress and reduce drag are of great importance for improving efficiency, hence reducing operating costs and environmental impact. The research will comprise of a detailed analysis of the effects of geometries such as arrays of micro pillars and ribs on boundary layer slip and wetting at the wall. These findings will then be used to generate effective boundary conditions which take into account the dynamics of the underlying slip surface for large scale simulations of the complete transition process. This will illustrate how coating a surface with these features can be best used to influence characteristics desired in particular flow regimes. Using the knowledge gleamed from the simulations, experiments will be performed to demonstrate the efficacy of the coatings and the validity of the boundary conditions at the wall.;172240,8;172240,8;FP7-PEOPLE-2009-IEF;/MC-IEF;IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE;UK;;;"/SCI;/EDU;/ITT";1;0;0;1;0;0 88778;230748;POEM;ONG;FP7-PEOPLE;PEOPLE-2007-4-3.IRG;FP7;Plasticity of Earth's mantle;2008-12-01;2012-11-30;;Plates tectonics theory is essentially justify by the physical and chemical properties of Earth’s minerals. Specifically olivine, the major mineral of the upper Earth’s mantle effectively controls the dynamics of the upper mantle and hence the interactions between the convective mantle and surface processes. Nevertheless, several processes are still poorly constrained. For instance, data on olivine plasticity at low temperature (T<1000oC) are crucially missing. The proposal is focused on the experimental determination of the plasticity of olivine under pressure and temperature conditions of uppermost Earth’s mantle. The objectives are to ascertain (1) the deformation mechanisms of olivine and olivine-rich rocks at conditions relevant of the mantle and (2) to quantify the plasticity as a function of the temperature and chemical environment (anhydrous or hydrous). An experimental and interdisciplinary approach has been designed. It associates high pressure and temperature deformation experiments on olivine single crystals in a Paterson vessel. The water content will be determined using FTIR. Mineral chemical compositions will be analyzed by EMPA. Finally, potential petrofabrics data will be acquired by EBSD. Geosciences Montpellier (France) has world-class analytical facilities and a strong multidisciplinary research group dedicated to the study of the Earth’s mantle and its dynamics. The applicant has a strong background in high pressure and temperature experimental methods and is well experienced in FTIR, techniques in which there are no researchers in Geosciences Montpellier. The collaboration with geodynamicists, and seismologists will broaden her research interests and open way to new projects. The “PoEM” project will thus allow a young European female researcher to stronger her professional career by establishing a sound research profile and promoting new collaboaration in France to those already established during her training years in Germany and the U.S.;100000;100000;FP7-PEOPLE-IRG-2008;/MC-IRG;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FR;;;"/SCI;/COO";1;0;0;1;0;0 105726;316596;ICE-DIP;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-ITN;FP7;Intel-CERN European Doctorate Industrial Program;2013-02-01;2017-01-31;http://openlab.cern/ice-dip;"ICE-DIP, the Intel-CERN European Doctorate Industrial Program, is an EID scheme hosted by CERN and Intel Labs Europe. ICE-DIP offers research training to 5 Early Stage Researchers (ESRs) in advanced Information and Communication Technologies (ICT). The technical goal of this program is to research and develop, through a public-private partnership, unparalleled capabilities in the domain of high throughput, low latency, online data acquisition. The interdisciplinary and interconnected research themes are the usage of many-core processors for data acquisition, future optical interconnect technologies, reconfigurable logic and data acquisition networks. These topics form a solid foundation for future cutting-edge data processing technologies of high interest to a broad range of industries. CERN, which has recently produced exciting hints of new physics with its Large Hadron Collider, is planning for future upgrades of its facilities. The research themes addressed by ICE-DIP are critical to the sustained forward momentum of European High Energy Physics and numerous other disciplines of science and technology. The results of this research will allow the partners to maintain technological leadership and produce significant transferable expertise which will be disseminated via the ESRs to the research and business communities. The unrivaled research experience and training resources of the partners guarantee a highest quality network for research and training. CERN and Intel Labs Europe have a track record of effective multidisciplinary and intersectoral actions. Academic rigour and training quality is ensured by the associate partners, National University of Ireland Maynooth and Dublin City University, where the ESRs will be enrolled in doctorate programmes. The network’s combined training program provides a unique environment for the ESRs to enhance their research potential, competitiveness and employment opportunities while accelerating European science.";1249027;1249027;FP7-PEOPLE-2012-ITN;/MC-ITN;EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH;CH;"INTEL RESEARCH AND DEVELOPMENT IRELAND LIMITED;INTEL RESEARCH AND INNOVATION IRELAND LIMITED";IE;/LIF;1;0;0;1;0;0 95719;251766;ALOE-DIVERSITY;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IEF;FP7;Phylogeny and ethnobotany: Testing predictive approaches to plant drug discovery in the genus Aloe L. (Asphodelaceae);2010-08-01;2012-07-31;;Dr Olwen Grace has worked at the Royal Botanic Gardens, Kew in the United Kingdom since 2004. She was recognised as a promising young scientist in South Africa where she began her research career in botany, and completed a part-time PhD in Plant Science at the University of Pretoria in 2009. This proposal, ALOE-DIVERSITY, is for a 24-month intra-European career development fellowship at the Pharmacognosy Laboratory in the Department of Medicinal Chemistry, University of Copenhagen in Denmark (host institution). Dr Grace will draw on a range of state-of-the-art molecular, biological, chemical and analytical techniques to produce the first robust phylogeny of Aloe (Asphodelaceae) including 200 taxa representing over a third of the diversity in this speciose genus, and novel chemical and bioactivity data for at least 50 Aloe species representing the phylogenetic diversity of the genus. The interdisciplinary nature of ALOE-DIVERSITY will significantly extend the evaluation of the ethno-guided and phylogenetic approaches to medicinal plant research. Aloe is a particularly appropriate candidate for this study due to the exceptional diversity, ethnobotanical and economic value of species such as Aloe vera L., as well as their medicinal properties and the growing concerns for their conservation. Through ALOE-DIVERSITY, Dr Grace will add new insights into predictive approaches to plant drug discovery and the identification of measures necessary to ensure the sustainable use of Aloe in future.;205629;205629;FP7-PEOPLE-2009-IEF;/MC-IEF;KOBENHAVNS UNIVERSITET;DK;;;"/SCI;/EDU;/ITT";1;0;0;1;0;0 105353;326429;ENERGY CHALLENGES 12;ONG;FP7-EURATOM-FISSION;Fission;FP7;TOMORROW'S ENERGY CHALLENGES 2012;2012-08-01;2013-01-31;;"Fukushima, on the 11th March 2011, triggered a widespread crisis of both confidence in the technical safety of nuclear systems and emotional concern, plunging the Western world into uncertainty! The Association FORM ENGELBERG strongly animated by its familiarity and expertise in the subjects of energy, environment and safety of technical systems, took the initiative on the 10th May 2011 to launch a high-level international conference in order to restore a climate of confidence. Independently of this decision, on the 28th June 2011, the European Union Council invited the European Commission to organize in 2013 a Symposium in Brussels: «involving a broad spectrum of stakeholders to the debate on the benefits and limitations of a low carbon economy» The results of the Conference ENERGY CHALLENGES 2012 will contribute to the preparation of this EU-2013 Symposium. Topics will cover a wide range of interest areas, including: risk governance and societal opinion, global strategies, energy efficiency, radioactive waste management, materials research, energy and mobility, strategic energy technology, and renewable energies, as well as education and training. The objectives of the ENERGY CHALLENGES 2012 conference are to answer questions such as: • Are there any technical or operational restrictions that would hinder the integration of nuclear energy into a system based on large and fluctuating supplies of renewable energy? • How will an energy system be affected by the extension of nuclear operating licences; economically and in terms of C02 emissions? • What are the macroeconomic costs of phasing out nuclear power and energy-political change? The Association FORUM ENGELBERG has 20 years of experience in organizing conferences on complex topics requiring a global and interdisciplinary scientific approach in order to support the political authorities to legislate.";382800;150000;FP7-Adhoc-2007-13;/CSA-SA;ASSOCIATION FORUM ENGELBERG;CH;;;"/RAD;/FIS";1;0;0;1;0;0 94297;236716;MSAPS;ONG;FP7-PEOPLE;FP7-PEOPLE-IEF-2008;FP7;Modelling the self-assembly of polymers in solution;2010-06-14;2012-06-13;;This project focuses on theoretical studies of polymers (long chain molecules) dissolved in a liquid. If a section of each molecule is incompatible with the solvent, the polymers may self-assemble into a range of structures in order to minimise the contact of this section with the liquid. This project will consider the self-assembly of polymers into vesicles (hollow spheres), which resemble those seen in cells and can also be used to encapsulate and deliver drugs. Novel polymers will be designed with the aim of producing batches of vesicles of uniform size, in order to allow the amount of encapsulated chemical to be precisely controlled. Next, the interaction between vesicles will be calculated, and the packing of a number of these objects will be considered. This problem is of relevance to signal transmission in nerves. Micelles (spheres of polymer molecules with no solvent core) will also be studied, to determine how they may be used to coat and hence modify the properties of a large particle or a surface. Finally, the process by which vesicles form will be investigated, since this determines how efficiently they encapsulate chemicals. Three different scenarios for vesicle formation will be considered and compared with experimental data from the host group and elsewhere. The theoretical work is based on the candidate's previous experience in calculations of polymer properties, and is linked to and sometimes directly inspired by experimental work performed in the host group. As required by the Work Programme, the proposal will increase the candidate's experience of interdisciplinary working through direct collaboration with experimental physicists and chemists, and continue his progress towards scientific independence through the performance of research largely based on his own ideas. All the research problems considered have been chosen with potential applications and relevance to industry in mind.;;164877,53;FP7-PEOPLE-IEF-2008;/MC-IEF;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FR;;;"/SCI;/EMP";1;0;0;1;0;0 98768;274356;SoCoRm;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-IEF;FP7;Social complexity in Resource Management;2011-04-11;2013-04-10;;"This research projects starts from the observation that in some instances, government intervention is effective in conserving renewable natural resources, such as fish stock, but not in others. We argue that government intervention does not take place in a vacuum, as sets of social norms may exist that govern resource use. In some cases these social norms promote sustainable harvesting strategies, but they may also aggravate overfishing if they are merely aimed at reducing costs of exploitation. Success or failure of government intervention depends crucially on how this intervention interacts with the local set of social norms. We hypothesize that these social norms are shaped by the state and dynamics of the natural resources and hence co-evolve with these resources. The key objective of this project is to analyze how decisions of resource users are influenced by the biological and institutional environment. Specifically, we aim to identify, first, under which conditions social norms of resource exploitation evolve; second, how quickly these social norms adapt and respond to environmental changes; and third, how government intervention interacts with these social norms. The execution of this research project is explicitly interdisciplinary and stimulates close cooperation between economists and biologists. We combine mathematical biology with economic modeling and behavioral experiments, to obtain a unique mix of methods allowing us to address the research topic. Our approach is innovative as we explicitly take into account that the institutional setting is not an exogenous constant, but over time, institutions are determined endogenously through the interplay between economic, social and ecological forces acting on the system. This research combines insights from behavioral and resource economics as it addresses under what circumstances formal government intervention can stimulate or crowd out self-regulation.";207979,2;207979,2;FP7-PEOPLE-2010-IEF;/MC-IEF;UNIVERSITETET I OSLO;NO;;;"/EMP;/EDU;/NET";1;0;0;1;0;0 108195;331159;NODOS;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IEF;FP7;Non-adiabatic quantum dynamics in novel optical superlattices;2013-04-01;2015-03-31;;"'The interdisciplinary boundary between the fields of quantum information science, condensed matter, and atomic physics is at the heart of the new field of 'quantum engineering'. One of the most important tools in this domain is ultracold atoms in optical lattices which are an ideal for testing condensed matter models and realising scalable quantum computation. For pratical implementation of quantum technology the challenge lies in realising the necessary dynamics with sufficient speed, sensitivity and robustness. This project will combine cutting-edge technologies of high resolution imaging and non destructive probing with an innovative realisation of super lattices to realise novel dynamics on the scale or microscopic, mesoscopic and macroscopic atom numbers. In addititon, I will use my extensive experience in the field of rapid, non-adiabatic processes to speed-up these processes allowing the step from proof of principle to the extremely high fidelities demanded for practical implementations.'";221154,6;221154,6;FP7-PEOPLE-2012-IEF;/MC-IEF;AARHUS UNIVERSITET;DK;;;/SCI;1;0;0;1;0;0 108188;329515;R-evolution pneumo;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IEF;FP7;The role of recombination in evolution and epidemiology of bacterial pathogen Streptococcus pneumoniae;2013-04-01;2015-03-31;;The aim of this project is to improve our understanding of the role of recombination (uptake and incorporation of foreign DNA) for the evolution and epidemiology of the major human bacterial pathogen Streptococcus pneumoniae, also known as the pneumococcus. There is an increasing appreciation of the public health significance of recombination in S. pneumoniae, where recombination has enabled major drug-resistant lineages to rapidly evade new conjugate vaccines. Here, I propose to investigate the role of different mechanisms of recombination in the context of (a) coevolution of the pathogen with the human immune system, (b) generation of novel antigenic diversity at the capsular locus, and (c) adaptation to clinical treatment by generation of novel bacterial lineages carrying multi-drug resistant genes and vaccine “escape” antigens. To do so, I will use an interdisciplinary approach of evolutionary microbiology, immunology, and epidemiology of infectious diseases. First, I will employ a generic evolutionary-epidemiological modelling approach to understand the population dynamic of recombination. Second, I will analyse newly available pneumococcal full-genome sequences to examine the link between recombination, immunity, vaccine, and drug-resistance in pneumococcus. The benefit of this research will be threefold. First, a better understanding of the role of recombination in coevolution with the human populations would be of benefit to the field of bacterial evolution and microbiology in general. Second, the approach outlined here can be applied to study recombination in other recombinogenic bacterial pathogens, like Neisseria meningitidis, Salmonella enterica or Helicobacter pylori. Finally, gaining further insight into the predicted long-term response against the current and future vaccines would help in the design of more effective forms of clinical interventions and help saving children’ lives.;221606,4;221606,4;FP7-PEOPLE-2012-IEF;/MC-IEF;IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE;UK;;;/SCI;1;0;0;1;0;0 90403;230636;GREEN ROOF SYSTEMS;ONG;FP7-PEOPLE;FP7-PEOPLE-IAPP-2008;FP7;Collaborative research and development of green roof system technology;2009-05-01;2013-04-30;;"In the last 20 years green roofs (vegetated layers that sit on top of the conventional roof surfaces of a building) have become relatively commonplace in Germany, Austria and Switzerland because of their role in urban stormwater management. In particular, the so-called ‘extensive’ green roof technology (very lightweight, low maintenance, vegetated roof surfaces) has been adopted widely because of its capacity to be ‘retro-fitted’ onto existing buildings, or incorporated onto new buildings without the need for major structural modification or support. Specific benefits of green roofs include: a) Overall reduction of rainfall run-off and attenuation of storm run-off; b) Summer cooling and reducing the urban heat island effect; c) Contribution to biodiversity e.g. ground-nesting birds; d) Improved quality of life for urban citizens; e) Extended roof life: a roof life is at least doubled with the addition of a green roof. This project seeks to establish a long term partnership between a leading commercial provider of green roof technology (Zinco) and an internationally leading research institution (University of Sheffield) through a collaborative programme of research and development and a suite of knowledge transfer activities. The project brings together established academic researchers with technicians, engineers and marketing specialists from Zinco each with highly relevant expertise in key areas. There is a balance of longer term and short term staff exchanges at different levels throughout the programme as well as recruitment of experienced researchers to fulfill particular tasks within the collaborative programme. This innovative programme of interdisciplinary research is targeted to fill a research gap that is constraining the development and exploitation of urban green roof technologies in the EU.";1185261;1185261;FP7-PEOPLE-IAPP-2008;/MC-IAPP;THE UNIVERSITY OF SHEFFIELD;UK;ZinCo GmbH;DE;/EDU;1;0;0;1;0;0 95324;252424;EYE POSITION;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IEF;FP7;How do cortical representations of eye position impact spatial cognition ?;2010-08-11;2012-08-10;;Eye position helps locate visual stimuli relative to head or body and thus, by aligning vision with other sensory and motor information may contribute to building abstract, multimodal maps for directing attention or for exploring the space. The cortical source of static eye position information has only recently been discovered and the function of eye proprioception in spatial behavior is unknown. Here I propose a research program to characterize the role of eye muscle proprioception in these complex cognitive functions. This proposal builds on my postdoctoral work which pioneered transcranial magnetic stimulation (TMS) as a method to interfere with cortical proprioceptive processing of eye position in humans. Lateral biases in attention and space exploration are core deficits in body-centered spatial hemineglect. The project will specifically test the hypothesis that a deficit in integrating eye proprioception information in the brain’s networks that subserve visual attention is a source for distorted spatial cognition in neglect. To this end and to exploit the TMS approach maximally I plan to combine it with neuropsychological characterization and lesion-symptom mapping, skills that I wish to learn from my host supervisor. Prof. Karnath is an internationally recognized expert in spatial cognition in healthy and neurological patient populations. I am an MD/PhD with 2 years postdoctoral research experience and a publication record that demonstrate that proprioceptive information can shape action and perception in the visual space.This project will therefore not only produce novel, timely and potentially clinical relevant knowledge about the role of eye proprioception in spatial behavior, but also provide the interdisciplinary training that would allow me to integrate complementary insights from the healthy population and neurological patients into a coherent model for spatial cognition.;161661;161661;FP7-PEOPLE-2009-IEF;/MC-IEF;EBERHARD KARLS UNIVERSITAET TUEBINGEN;DE;;;"/SCI;/EDU;/ITT";1;0;0;1;0;0 90065;230195;FUTURESOC;ONG;FP7-IDEAS-ERC;ERC-AG-ID1;FP7;Forecasting Societies Adaptive Capacities to Climate Change;2009-03-01;2014-07-31;;"This interdisciplinary project (combining social and earth sciences) addresses a key gap in the knowledge of global assessments concerning the likely consequences of future climate change on future human wellbeing. More information about the determinants of future adaptive capacity is necessary for setting policy priorities today: Should the significant funds allocated for adaptation be invested in enhancing existing infrastructure or currently practiced agricultural strategies (some of which may not be tenable under future climates), or should they invest alternatively in enhancing human empowerment through education and health which in consequence will enable affected societies to better cope with whatever challenges the future will bring? This study is expected to bring significant progress in this difficult multidisciplinary, yet highly relevant, field through a combination of: (a) New global science-based, long-term projections of human capital (population by age, sex and level of education) as a key element of adaptive capacity; (b) Three empirical multi-national studies on key factors involved in past vulnerability and adaptations to the Sahelian drought, Hurricane Mitch and the Asian tsunami; (c) Three prospective case studies assessing future adaptive capacity for the Phuket region, Mauritius and the Nicobar islands; (d) All held together and put into perspective by the elaboration of a new demographic theory of long-term social change with predictive power. This rather complex project structure is necessary for reaching generalizable and useful results. All components have been designed to complement each other to maximize the chances of achieving path-breaking and at the same time tangible results in this highly complex, multidisciplinary field. All components of the study will build on previous work of IIASA and Wolfgang Lutz and hence minimize the need to acquire additional experience for the case study sites or for the methodology used.";2438402;2438402;ERC-2008-AdG;/ERC-AG;INTERNATIONALES INSTITUT FUER ANGEWANDTE SYSTEMANALYSE;AT;;;/SCI;1;0;0;1;0;0 96517;254747;RHOMECHANOVASC;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IOF;FP7;Regulation of Rho proteins by mechanical forces in the vascular system;2010-08-01;2013-08-31;;"As molecular links between mechanosensors and the regulation of cellular processes Rho proteins have a critical position in mechanotransduction. Interestingly during cardiovascular disease (CVD) involving aberrant hemodynamic forces Rho proteins are activated. How do mechanical forces regulate Rho proteins? How do they contribute to the mechanical adaptation of the cell? And How is this mechanism altered during CVD? To answer these questions we have designed a proposal in two phases with interdisciplinary approaches including biochemical assays, three dimensional force microscopy (3DFM) and in vivo analysis. 1.Outgoing phase: To determine how mechanical forces activate Rho proteins and to evaluate the involvement of Rho proteins during the mechanical adaptation to force. We will identify the mechanism of Rho proteins activation using an innovative biochemical assay developed in the host lab and we will evaluate their involvement in mechanical adaptation of the cell using 3DFM. 2.Return phase: To evaluate the pathophysiological relevance of the mechanisms identified during the first phase. We will determine the cellular functions downstream of the regulators identified during phase 1 and we will investigate their activities in two animal models of altered hemodynamic forces by using the small animal physiology core facility available in the return host. The proposed project will yield new insights in different areas of life science from fundamental cell biology to potential identification of new therapeutic targets. First the anticipated results will contribute to better understand how the cells modify their mechanical properties in response to force. This crucial mechanism is central in many aspects of biology. We will also evaluate the modulation of Rho regulators in animal models of CVD; this will permit identification of new pharmacological targets for this public health problem.";213108,3;213108,3;FP7-PEOPLE-2009-IOF;/MC-IOF;INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE;FR;;;"/LIF;/EDU";1;0;0;1;0;0 96062;255604;SUPRA-DYN;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IEF;FP7;Dynamics of Soft Metallo-Supramolecular Materials from Entangled Macromolecular Precursors;2010-10-01;2012-09-30;;Our project deals with the class of supramolecular systems coined “metallo-supramolecular polymers”, which offer several advantages compared to their covalent counterparts, e.g. a “self-healing” mechanism due to the reversibility of the supramolecular bond. The specific systems based on metallo-terpyridine complexes binding covalent macromolecular precursors, which have been developed at University Catholique de Louvain (UCL) [Guillet et al. (2009)] provide unique tunability and simplicity making them ideal model systems to test supramolecular dynamics and stimuli responsive behavior on well defined supramolecular architectures, such as stars or hierarchically branched structures. The host at UCL has great expertise and a number of collaborations on advanced polymeric systems, e.g. telechelic polymers, ionomers as well as supramolecular systems, and the work will benefit tremendously from this strong theoretical and materials support. The applicant brings a very beneficial research experience in structure-property relationships of polymeric systems, in various and partly combined experimental techniques, such as rheology with combined scattering or nuclear magnetic resonance (NMR) as well as in molecular modelling, which will allow a productive research focused on the “tunability” of materials. The opportunity to locally team-up with experts in the field of molecular modelling, materials characterization and synthetic organic chemistry provides an excellent perspective for an interdisciplinary approach in the proposed project. Thus, the applicant will be able to develop a strong expertise in polymeric systems and soft condensed matter.;159600;159600;FP7-PEOPLE-2009-IEF;/MC-IEF;UNIVERSITE CATHOLIQUE DE LOUVAIN;BE;;;"/SCI;/EDU;/ITT";1;0;0;1;0;0 102047;290805;FREE;ONG;FP7-SSH;SSH.2011.5.2-1;FP7;Football Research in an Enlarged Europe: Identity dynamics, perception patterns and cultural change in Europe’s most prominent form of popular culture;2012-04-01;2015-03-31;http://www.free-project.eu/;"The FREE project aims at understanding the impact of the most popular and most widely shared of all expressions of popular culture - football - on identity dynamics in an enlarged Europe. In a truly interdisciplinary perspective FREE seeks to explore an apparently non-political, but fully existing sub-cultural European public space of communication: the European football scene in the largest sense. FREE will bring together different approaches to this European public space: a) it will study how collective memories of popular culture have emerged during the history of European football, what trace they have left in mutual perception patterns across the continent and to what extent cultural commonality may grow out of historically grown diversity in the field of everyday culture; b) it will carry out multi-dimensional empirical research work that is innovative both in design and scope, in order to produce new insight into the complex identity dynamics resulting from processes of Europeanisation of football and strongly increased mobility over the last two decades; c) it will attempt to shed light on the issues raised by the growing feminisation of the game such as gender construction and attitudes toward traditional patterns of identification; d) it will provide an in-depth analysis of changing perceptions of European approaches to football governance as a legitimacy-enhancing project and produce strategic recommendations for policy-makers and other stakeholders in this field. Through an ambitious dissemination strategy the FREE project aims at increasing awareness among citizens, stakeholders and policy-makers about the issue of cultural diversity and commonality in the field of popular culture and its often underestimated impact on the political, economic and social dimensions of the European integration process.";3026213,16;2433357,16;FP7-SSH-2011-2;/CP-FP;ECOLE SUPERIEURE DES SCIENCES COMMERCIALES D ANGERS ASSOCIATION;FR;"UNIWERSYTET IM. ADAMA MICKIEWICZA W POZNANIU;UNIVERSITAT WIEN;UNIVERSITE DE FRANCHE-COMTE;UNIVERSITAT DE VALENCIA;KOBENHAVNS UNIVERSITET;LOUGHBOROUGH UNIVERSITY;UNIVERSITAET STUTTGART;MIDDLE EAST TECHNICAL UNIVERSITY";"PL;AT;FR;ES;DK;UK;DE;TR";/SOC;1;0;0;1;0;0 102530;304073;VISCELTURBFLOW;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-CIG;FP7;Computational study of macro- and microscopic turbulence controlled by polymer additives;2012-03-01;2016-02-29;;"The goal of this project is the study of a multiscale challenge of fluid mechanics, polymer dynamics in flow, one that spans from molecular to macroscale. In spite of decades of research on the dynamics of single polymers in flow, polymer drag reduction, early turbulence, and more recently elastic turbulence, a comprehensive and predictive knowledge of polymer-polymer and polymer-flow interactions still elude us. Consequently, industrial applications of polymers' abilities to control turbulence, heat transfer in single or multiphase flows, or enhancing mixing at microscopic scales have yet to exploit the full potential of polymer dynamics. It is proposed to develop an interdisciplinary research program around multiscale numerical algorithms developed to address the shortcomings of current numerical approaches used for viscoelastic fluids in turbulent, or turbulent-like, flows. The intellectual merit of the proposal is to study an area of fluid mechanics with many remaining open questions that pertains to the fundamental properties of turbulent transport and mixing. The broader impacts of the proposed research are (1) to advance the state of the art of predictive theories and models of polymer dynamics in flow, (2) to contribute to the general knowledge of turbulence control and mixing, (3) to demonstrate the benefits of the proposed research in turbulence drag control, heat transfer manipulation and mixing applied to practical problems.";100000;100000;FP7-PEOPLE-2011-CIG;/MC-CIG;UNIVERSITE DE LIEGE;BE;;;/SCI;1;0;0;1;0;0 92163;239260;FDBKCOMM;ONG;FP7-PEOPLE;PEOPLE-2007-4-3.IRG;FP7;"Feedback and Tow-Way Communication Systems";2009-04-01;2013-03-31;;"This proposal investigates the role of feedback in communication networks, with the ultimate goal of providing architecture-level guidance in the design of robust and efficient communication systems. Many common communication situations are over inherently two-way channels, such as wireless networks, digital subscriber lines (DSL), and the Internet, even when the information transfer is only in one direction. Thus we can receive feedback from the other end of the channel, which we can use to improve the quality of communication. Even though feedback is present in many communication systems and is used in certain primitive forms, such as channel estimation and automatic repeat request (ARQ), the theory underlying its use has not been completely developed. We propose new approaches for several communication settings, such as single-user channels with memory, multiple-user channels with feedback, compound channels with feedback, and two-way channels, in which two or more users simultaneously exchange information through a shared channel. The proposed research is based on integrating new mathematical and engineering tools into the communication problems. In particular, we will integrate the idea of causality and directed information and use optimization tools from operational research to derive schemes that achieve that capacity. Overall, the proposed research aims to advance a theoretical understanding of feedback in communication and to give practical guidance for robust feedback communication systems. While positive results will provide a novel communication system design, negative results will prevent over-engineering and allow more confidence in simple and modular implementations. Since feedback and causality also constitute a pivotal concept in biology and economics, a deeper understanding of the role of feedback in communication will lead to a better understanding of the role of feedback in a broader interdisciplinary context.";100000;100000;FP7-PEOPLE-IRG-2008;/MC-IRG;BEN-GURION UNIVERSITY OF THE NEGEV;IL;;;"/SCI;/COO";1;0;0;1;0;0 103587;302315;NBC-ReGen4;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IEF;FP7;Nanostructured & Biomimetic Ceramic-Polymer Composites for Bone Tissue Regeneration;2012-09-01;2014-08-31;;The interdisciplinary proposal NBC-ReGen4 is based on the existing expertise in materials science of the incoming European Fellow (Dr. Piergiorgio Gentile) in combination with the host laboratories knowledge of biocompatibility assessment and medical device development (University of Sheffield-Scientist in charge: Prof. P.V. Hatton). NBC-ReGen4 is a timely project with respect to the scientific and technological advance on the state-of-the-art and with clear translational relevance to industry and ultimately patients. It aims to produce, characterise and evaluate a series of nanostructured composites with significantly improved properties compared to the existing state-of-the-art, specifically including suitable membranes for guided bone regeneration. Conceptually, the adaptation of nanostructured composite membranes for the development of functional devices in different applications represents a major step forward in the increasingly competitive field of tissue engineering and regenerative medicine. It is also an ideal time to train a talented materials scientist in new methods related to biological evaluation of a biomaterial, as well as transferable skills that will significantly boost his career prospects and opportunities to contribute to society. In detail, in NBC-ReGen4 the innovative composite membranes will be based on commercially available or in-house fabricated calcium phosphate particles incorporated into a resorbable medical polymer matrix (polyglycolic acid or poly(lactide co-glycolide)) further processed by electrospinning. The obtained composite membrane will consist in bilayered structures that can be modified and characterised for specific applications where bone tissue regeneration is required on only one side. Surface functionalization of the different layers to enhance specific properties (such as biomimetic and anti-inflammatory properties) by low-risk and environmentally-friendly techniques, will be also implemented.;200371,8;200371,8;FP7-PEOPLE-2011-IEF;/MC-IEF;THE UNIVERSITY OF SHEFFIELD;UK;;;/SCI;1;0;0;1;0;0 97115;251763;DOUBLELICHT;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IEF;FP7;Double-site ligands for the inhibition of Cholera toxin;2011-01-01;2012-12-31;;Specific binding between bacterial enterotoxins and oligosaccharides on the host cell membrane is a paradigm for protein-sugar interaction. One of the best characterized recognition pairs is formed by ganglioside GM1 and the cholera toxin (CT). Recently, Krengel´s group has identified a second binding site, which appears to be present in the close CT congener LT and in CT from the El Tor strain, responsible for the current cholera pandemic. This binding site, which is clearly distinct from the primary GM1 binding site, recognizes blood group ABO antigens, fucosylated carbohydrate structures carried on both glycolipids and glycoproteins. The main objective of our project is to develop new dual-site ligands for cholera toxin inhibition featuring 2 pharmacophoric fragments, a GM1 mimic and a blood group mimic, connected across a linker able to span the two binding sites of enterotoxins. The GM1 binding site will be targeted using a functionalized GM1 mimic recently developed in the host laboratory which binds to CT and allows conjugation to aglycons. The blood group binding site will be targeted by selecting the mimimal blood group epitope using STD NMR experiments. Linkers of different lengths will be built in modular fashion by connecting PEG monoamine fragments using squaric acid connectors. Optimal linker length will be selected by combinatorial target-guided dynamic synthesis of a disulfide library in the presence of hLTB or CTB/hLTB toxin hybrids as templates. The required proteins will be obtained through a collaboration with the Krengel group. This project is connected to the activities of the COST D34/001/05 WG, working on cholera toxin inhibition and sensing. This fellowship and the framework provided by the COST group will ensure the opportunity for the proposer to be exposed to an interdisciplinary context while working on a timely scientific project resulting from the coordinated efforts of internationally recognized research leaders in glycoscience.;172939,4;172939,4;FP7-PEOPLE-2009-IEF;/MC-IEF;UNIVERSITA DEGLI STUDI DI MILANO;IT;;;"/SCI;/EDU;/ITT";1;0;0;1;0;0 89504;217346;EDC2020;ONG;FP7-SSH;SSH-2007-8.0-01;FP7;European Development Co-operation to 2020;2008-04-01;2011-03-31;http://www.edc2020.eu/;This is an important moment in the history of Europe's development policies and it’s relations with developing countries. Over the next decade a combination of old and new domestic issues and substantial changes in the global landscape require a reshaping of Europe’s development policies. These include challenges facing EU’s development policy agenda through new actors in international development, issues around energy security and climate change. All these changes take place in times of wide-ranging global challenges, and at a time when questions of European identity loom large in national debates. A key questions will remain: How will member states approach the issue of working together on common problems? It is crucial for decisions on the emerging matters to be based on good research and sound evidence. The public and policymaking debate needs to be informed by research voices. To this end, the overall objective is “to improve EU policy-makers’ and other societal actors’ shared understanding of emerging challenges facing EU development policy and external action.“ In addition it seeks to understand how EU development policymaking processes work and why or how EU policies then change or remain the same. EDC2020 will contribute to this objective by promoting interaction across the research and policy arenas to share perspectives, learn from each other, and strengthen working relationships through policy-oriented publications, a shared project website and high-level European policy forums. The proposal contributes to the work programme as it is addressing ‘new challenges’ which go beyond the issues touched by SHH work programme 2007 and take a wider and longer term view of the challenges facing concerned policy fields. In order to effectively contribute to the work programme both in promoting understanding and drawing the attention of the policy-makers, the project has strong interdisciplinary approach and communication components.;1495676,54;1333739;FP7-SSH-2007-1;/CP-FP;EUROPEAN ASSOCIATION OF DEVELOPMENTRESEARCH AND TRAINING INSTITUTES - EADI EUROPAISCHER VERBAND DER ENTWICKLUNGS- FORSCHUNGS- UND AUSBILDUNGS;DE;"DEUTSCHES INSTITUT FUER ENTWICKLUNGSPOLITIK;FUNDACION PARA LAS RELACIONES INTER NACIONALES Y EL DIALOGO EXTERIOR FRIDE;INSTITUTE OF DEVELOPMENT STUDIES;Society For International Development, Chapter Netherlands;OVERSEAS DEVELOPMENT INSTITUTE";"DE;ES;UK;NL";/SOC;1;0;0;1;0;0 104611;299112;Paris-Cracow-Venice;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IEF;FP7;Paris-Cracow-Venice. The European Festivals for Henri de Valois, King of Poland, 1573–74;2012-12-01;2014-11-30;http://pariscracowvenice.wordpress.com/;"The aim of the project is to provide the first multidisciplinary monograph and comparative analysis of one of the most splendid celebration in early modern Europe: the festivals staged for Henri de Valois, as king of Poland, in France, Poland and Italy before his accession to the French throne as Henri III. These lavish displays of the wealth and power of the monarchy were produced by the most acclaimed artists, musicians and dancers, working under the guidance of poets and humanists who were responsible for devising elaborate and erudite programmes. Carefully described and commented upon, the festivals provide us with incomparably rich resources to investigate the cultural and intellectual history of the early modern period. The festivals for Henri de Valois have been examined by many of the foremost scholars working on the Valois court. Until this time, however, no studies have given a comprehensive reconstruction and analysis of these festivals or provided a satisfactory interpretation of them. This survey, based on mostly unpublished primary sources in Latin, French, Polish and Italian, will engage with political history, art history, dance history, music history, and history of science and will be centred in literary history. The study will contribute to an understanding of how royal imagery was shaped and perceived in different parts of the continent, and they offer a new model for the study of Renaissance festivals, their meanings and their purposes. It will also raise the issues of the artistic, intellectual and political exchanges between France and Italy as well as between Western and Central Europe. The candidate, a Polish art historian specialised in French art, will be based at the Warburg Institute where she will receive an advanced training in interdisciplinary research on the European Renaissance, with a special reference to the sixteenth-century Italian culture and language.";200371,8;200371,8;FP7-PEOPLE-2011-IEF;/MC-IEF;UNIVERSITY OF LONDON;UK;;;/SCI;1;0;0;1;0;0 106277;306357;NANO-JETS;ONG;FP7-IDEAS-ERC;ERC-SG-PE8;FP7;Next-generation polymer nanofibers: from electrified jets to hybrid optoelectronics;2013-03-01;2018-02-28;;'This project ultimately targets the application of polymer nanofibers in new, cavity-free lasers. To this aim, it wants to tackle the still unsolved problems of the process of electrospinning in terms of product control by the parameters affecting the dynamics of electrified jets. The electrospinning is based on the uniaxial elongation of polymeric jets with sufficient molecular entanglements, in presence of an intense electric field. It is a unique approach to produce nanofibers with high throughput. However, the process is still largely suboptimal, the most of nanofiber production being still carried out on an empirical basis. Though operationally simple, electrospinning is indeed complex as the behavior of electrified jets depends on many experimental variables making fully predictive approaches still missing. This project aims to elucidating and engineering the still unclear working principles of electrospinning by solutions incorporating active materials, with a tight synergy among modeling, fast-imaging characterization of electrified jets, and process engineering. Once optimized, nanofibers will offer an effective, well-controllable and cheap material for building new, cavity-free random laser systems. These architectures will enable enhanced miniaturization and portability, and enormously reduced realization costs. Electrospun nanofibers will offer a unique combination of optical properties, tuneable topography and light scattering effectiveness, thus being an exceptional bench tool to realize such new low-cost lasers, which is the second project goal. The accomplishment of these ambitious but well-defined objectives will have a groundbreaking, interdisciplinary impact, from materials science to physics of fluid jets in strong elongational conditions, from process to device engineering. The project will set-up a new, internationally-leading laboratory on polymer processing, making a decisive contribution to the establishment of scientific independence.';1491823;1491823;ERC-2012-StG_20111012;/ERC-SG;UNIVERSITA DEL SALENTO;IT;CONSIGLIO NAZIONALE DELLE RICERCHE;IT;"/PSE;/EAR";1;0;0;1;0;0 87417;207279;EUNACON;ONG;FP7-IDEAS-ERC;ERC-SG-SH2;FP7;The European and National Constitutional Law Project;2008-09-01;2013-02-28;;Irrespective of whether the Treaty establishing a Constitution for Europe or a Reform Treaty enters into force, the EU already has a constitution by all but name. But what does it rest on? Both the current treaties and the European Court of Justice often make reference to the national constitutions, either of one Member State individually, or as common constitutional principles and traditions. Yet, whilst the influence of EU law on national constitutional law is well documented, no thorough comprehensive comparative legal research has ever been done into these common constitutional principles. The very foundations of the European constitution have thus remained uncharted. Trans-national comparative constitutional law has been neglected in the scientific research on the European Constitution, while it should be an essential component of the analysis. This project aims to contribute to the scientific debate by going back to the fundamentals of national constitutional law. Its purpose is to analyse and structure common legal constitutional principles across EU Member States and identify constitutional diversity. To that end a team of PI and four post-docs will conduct a comprehensive analysis of the „constitutional law in action” of selected Member States, as expounded in constitutional case law, practice and texts. The functional method of comparative law will be used, analysing constitutional law as it functions in practice. Also, these themes will be analysed in an interdisciplinary fashion, taking account of other disciplines. It is this method which makes this research innovative: the national lines will be crossed, and system-neutral themes be used as a starting point, in order to formulate common principles as well as identify national diversity. It will thus advance the scientific debate on constitutionalism in the EU, and contribute to embedding it in common constitutional traditions, leaving room, where necessary, for national constitutional diversity.;1645056;1645056;ERC-2007-StG;/ERC-SG;UNIVERSITEIT MAASTRICHT;NL;STICHTING KATHOLIEKE UNIVERSITEIT BRABANT;NL;/SOC;1;0;0;1;0;0 103218;299214;DECOMFORECO;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IEF;FP7;Litter decomposition in forest ecosystems: assessing the functional role of climate, litter quality and soil organisms;2013-03-15;2015-03-14;https://www.sites.google.com/site/pablogarciapalacios1/home/Marie-Curie-Project;At global scales, the carbon returned to the atmosphere through litter decomposition is a key component of the total annual carbon flux. Therefore, the study of factors controlling decomposition (climate, litter quality and soil organisms) has important implications for present and future global carbon budgets. This proposal aims to explore the relationship between biodiversity and decomposition along climatic gradients in forest ecosystems. Contrary to most previous investigations, it focuses on the effects of functional diversity at three trophic levels (producers, decomposers and detritivores), rather than on taxonomic diversity, in order to bridge aboveground and belowground diversity with decomposition. The proposed research consists of three general objectives to be evaluated at different spatial scales: i) to dissect the interactive effects of plant litter and decomposer diversity on decomposition across major European forest biomes, ii) to assess the relative roles played by climate, litter quality and soil organisms on decomposition in a Euro-Mediterranean region, and iii) to assess the interactions between litter quality and both soil fauna and microorganisms functional diversity upon short-term decomposition. The complementary nature of the different approaches (i) continental database, ii) litter transplant in the field, and iii) growth chamber experiments), and the use of state-of-the-art analytical tools (e.g. molecular techniques, functional diversity indexes and modelling) assure the interdisciplinarity of this proposal. The applicant will be trained on the use of molecular techniques and on the determination of several groups of soil fauna. Additionally to technical formation, the applicant will acquire planning and coordination network skills, very useful to work with international and multidisciplinary teams. All together assure the life-long training and career development of the applicant as a highly promising and independent European researcher;201932,4;201932,4;FP7-PEOPLE-2011-IEF;/MC-IEF;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FR;;;/SCI;1;0;0;1;0;0 94201;247220;SEACHANGE;ONG;FP7-IDEAS-ERC;ERC-AG-PE10;FP7;Sea-level change due to climate change;2010-04-01;2016-03-31;;Sea-level rise as a consequence of climate change will have severe impacts on coastal populations and ecosystems. However, owing to the incomplete state of scientific knowledge, there is a large range of uncertainty in the predictions, of a factor of more than two for any given emissions scenario during the 21st century, and much larger for subsequent centuries. This is a serious obstacle to the assessment of impacts. Sea-level change is a diagnostic of a complex combination of Earth system processes operating over a wide range of timescales. Explaining the record of past sea-level change and predicting the future is therefore a fascinating interdisciplinary scientific challenge as well as one with practical implications. The aim of this project is to improve quantitative understanding and hence reduce uncertainty in predictive models of the two main climate-related contributions to sea-level change, namely ocean density change and changes in ice-sheets. The former is the most important term on timescales of years to centuries, and the latter is the principal influence over timescales of centuries to millennia. In both parts of the proposal, our focus is on analysis of changes simulated by 3D atmosphere-ocean climate models, which we compare with observational data. For ocean density change, the objectives are to analyse the physical processes responsible for global-mean and local sea-level change due to density change, in order to quantify and constrain the uncertainties in predictions. For ice-sheets, the objectives are to increase our understanding of and ability to model the coupled evolution of ice-sheets and climate on multi-millennial timescales, in particular regarding the last glacial cycle and the long-term future of the Greenland ice-sheet.;1441719;1441719;ERC-2009-AdG;/ERC-AG;THE UNIVERSITY OF READING;UK;;;"/PSE;/ENV;/EAR";1;0;0;1;0;0 105350;320070;BARIUM;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-CIG;FP7;BARIUM CYCLING IN ANTARCTIC WATERS: UNDERSTANDING PRESENT AND PAST OCEAN PROCESSES;2012-10-01;2016-09-30;http://oceanbarium.wordpress.com/;"Ice core records show that atmospheric carbon dioxide (pCO2), an important greenhouse gas that drives and amplifies climate change, varies naturally over a range of timescales. Biological productivity in the oceans is a major contributor to carbon drawdown, and an important factor controlling atmospheric pCO2. The Southern Ocean is linked with these climatic events, in part due to upwelling and subduction of deep waters during which carbon and heat are exchanged with the atmosphere, and partly because it exerts a primary control on the distribution of nutrients to a large portion of the modern ocean, which in turn regulates algal population structure and carbon uptake. The aim here is to further the understanding of oceanic carbon storage over a range of timescales in the region of the West Antarctica Peninsula, the region experiencing the most rapid atmospheric and oceanic warming in recent decades. Here, I propose to utilize components of the biogeochemical cycle of barium (Ba) to understand and investigate different aspects of organic and inorganic carbon storage. Ba cycling has been a focus of chemical oceanography and palaeoclimate studies for over twenty years, and can provide uniquely an insight into both organic and inorganic carbon storage. The analyses carried out during the reintegration period will provide data suitable for testing hypotheses linking Southern Ocean circulation to global climate over a range of timescales, and linking the response in biogeochemical cycles to future climatic change. The work will be interdisciplinary, linking in other aspects of the long term monitoring programs along the WAP, such as physical oceanography, meteorology and ecology, and investigating modern and past climatic processes. If successful, the Marie Curie grant will fund a PhD student, who will be supervised by the Career Integration Grant fellow, providing opportunities for teaching experience and student training.";100000;100000;FP7-PEOPLE-2012-CIG;/MC-CIG;UNIVERSITY OF BRISTOL;UK;CARDIFF UNIVERSITY;UK;/LIF;1;0;0;1;0;0 100009;288254;REDUCTION;CLO;FP7-ICT;ICT-2011.6.6;FP7;Reducing Environmental Footprint based on Multi-Modal Fleet management System for Eco-Routing and Driver Behaviour Adaptation;2011-09-01;2014-08-31;;Reduction of CO2 emissions is the great challenge of the transport sector nowadays. Despite progress in vehicle manufacturing and fuel technology, additional innovative technologies are needed to address this challenge. According to the Int. Assoc. of Public Transport, a significant fraction of CO2 emissions in EU cities is resulting from public transport and other mass transport means, which are commonly organized into multi-modal transport fleets, because their vehicles have, on average, nearly substantial mileage and fuel consumption.
The REDUCTION project focuses on advanced ICT solutions for managing multi-modal fleets and reducing their environmental footprint. REDUCTION collects historic and real-time data about driving behaviour, routing information, and emissions measurements, that are processed by advanced predictive analytics to enable fleets enhancing their current services as follows: 1) Optimizing driving behaviour: supporting effective decision making for the enhancement of drivers' education and the formation of effective policies about optimal traffic operations (speeding, braking, etc.), based on the analytical results over the data that associate driving-behaviour patterns with CO2 emissions. 2) Eco-routing: suggesting environmental-friendly routes and allowing multi-modal fleets to reduce their overall mileage automatically. 3) Support for multi-modality: offering a transparent way to support multiple transportation modes and enabling co-modality.
REDUCTION follows an interdisciplinary approach and brings together expertise from several communities. Its innovative, decentralized architecture allows scalability to large fleets by combining both V2V and V2I approaches. Its planned commercial exploitation, based on its proposed cutting-edge technology, aims at providing a major breakthrough in the fast growing market of services for 'green' fleets in EU and worldwide, and present substantial impact to the challenging environmental goals of EU.;3971742;2800000;FP7-ICT-2011-7;/CP;STIFTUNG UNIVERSITAT HILDESHEIM;DE;"AARHUS UNIVERSITET;TRINITE AUTOMATISERING B.V.;TRAINOSE METAFORES-METAFORIKES YPIRESIES EPIVATON KAI FORTIOU AE;NORDJYLLANDS TRAFIKSELSKAB;PANEPISTIMIO THESSALIAS;DELPHI DEUTSCHLAND GMBH;CTL CYPRUS TRANSPORT LOGISTICS LIMITED;AALBORG UNIVERSITET;GOTTFRIED WILHELM LEIBNIZ UNIVERSITAET HANNOVER";"DK;NL;EL;DE;CY";/EST;1;0;0;1;0;0 86706;211928;ERA-INSTRUMENTS;ONG;FP7-INFRASTRUCTURES;INFRA-2007-3.0-01;FP7;Infrastructure Funding in the Life Sciences;2008-04-01;2011-09-30;;It has become increasingly obvious that concepts and strategies for research infrastructure (RI) funding should be harmonised and coordinated within the EU. ESFRI has determined requirements for European RI funding and has presented a roadmap. Growing attention is paid to life sciences that rely on RIs of a less centralised, but more networked dimension. There is a clear need for action in the interdisciplinary area between physics, chemistry, biology and medical sciences as cutting edge instrumentation becomes increasingly expensive and, yet, indispensable for world-class research. However, promotion of research policies, apart from the ESFRI projects, has been restricted so far to national efforts without managing these actions with a European view. Funding and research organisations can not afford to remain at the national stage with world-wide competition for the best scientists and the most promising projects. Frontier research is international since long and funding organisations have to follow scientists to the European level. ERA-Instruments aims at initiating coordination and a sustainable network of ministries, charities, funding agencies and research councils active in funding of life science RI. This European platform of relevant stake-holders will set up comprehensive tools for adequate treatment of instrumentation related topics enabling conclusions for research policies on both a national and European level. The ERA-NET will focus on bioanalytical instrumentation (incl. post-genomic high-throughput techniques) such as NMR, mass spectrometry, microscopy, microarray platforms etc. These mid-size equipments have become an essential and strategic strength for European countries. The ERA-NET can build on the broad experience with RI funding of its partners. Contacts to the scientists will thus remain close and continuous. Promotion of RI funding in FP-7 and support for new member states will also strengthen the position of European research.;1497196,85;1199911;FP7-INFRASTRUCTURES-2007-1;/CSA-CA;DEUTSCHE FORSCHUNGSGEMEINSCHAFT;DE;"NEDERLANDSE ORGANISATIE VOOR WETENSCHAPPELIJK ONDERZOEK;THE ICELANDIC CENTRE FOR RESEARCH;HARIDUS-JA TEADUS MINISTEERIUM;AGENZIA NAZIONALE PER LE NUOVE TECNOLOGIE, L'ENERGIA E LO SVILUPPO ECONOMICO SOSTENIBILE;AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS;HERMANN VON HELMHOLTZ-GEMEINSCHAFT DEUTSCHER FORSCHUNGSZENTREN EV;CONSIGLIO NAZIONALE DELLE RICERCHE;BIOTECHNOLOGY AND BIOLOGICAL SCIENCES RESEARCH COUNCIL;ETHNIKO IDRYMA EREVNON;THE WELLCOME TRUST LIMITED;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;MEDICAL RESEARCH COUNCIL;THE CZECH SCIENCE FOUNDATION;BUNDESMINISTERIUM FUER DIGITALISIERUNG UND WIRTSCHAFTSSTANDORT;FONDS VOOR WETENSCHAPPELIJK ONDERZOEK-VLAANDEREN";"NL;IS;EE;IT;ES;DE;UK;EL;FR;CZ;AT;BE";/SCI;1;0;0;1;0;0 104900;321957;DIFNONLOC;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-CIG;FP7;Diffusive Partial Differential Equations with Nonlocal Interaction in Biology and Social Sciences;2012-10-01;2016-09-30;;"In the presented project we shall develop the analytical theory for a large class of diffusive partial differential equations with nonlocal interaction and related models, having an interdisciplinary set of applications ranging from population biology and microbiology to material science and sociology. In particular, we shall study the existence and uniqueness theory for those models, the qualitative behaviour, the large time behaviour, their microscopic to macroscopic interplay, and singular perturbation problems. Recurring keywords are the Wasserstein gradient flow theory (both in the classical sense, and in the direction of models with nonlinear mobility), and the Entropy solution theory for nonlinear conservation laws. One of the most innovative aspects of this project will be to provide a link between those two theories. A new theory with many species within the mentioned gradient flow setting will be developed. We shall focus in particular on models for pedestrian movements, featuring a highly nonlinear and nonlocal structure, which requires a new approach within the framework of scalar conservation laws. The duality between aggregative behaviour (finite time blow up, formation of spatial patterns) and diffusive behaviour (local repulsion, large time decay, self similar decay) is behind many of the studied problems, as it provides complexity in the large time behaviour with respect to initial data and parameters of the problem. The project will last 4 years, and it will be implemented through a series of activities: research collaborations of the fellow in various universities in UK, Germany, and Italy, 4 events (conferences, summer schools, etc), and 4 mid term visiting period at the host institutions by top class researchers. The host institution is the University of Bath, which provides a permanent Reader position in Applied Mathematics for the fellow. The project will be partly co-funded by other projects (among which the FIRST network, expiring in 2013).";100000;100000;FP7-PEOPLE-2012-CIG;/MC-CIG;UNIVERSITY OF BATH;UK;;;/LIF;1;0;0;1;0;0 96879;263549;HISTANTARTSI;ONG;FP7-IDEAS-ERC;ERC-SG-SH5;FP7;Historical memory, Antiquarian Culture and Artistic Patronage: Social Identities in the Centres of Southern Italy between the Medieval and Early Modern Period;2011-01-01;2016-05-31;;"From the 12th-century southern Italy was overrun by foreign rulers and their houses and saw fierce dynastic struggles for succession. In attempting to cope with these sudden changes and upheavels, the local urban communities continually found themselves faced by the need to legitimize and reconfirm their status through actual negotiations with the king, and eventually with the baron. In this context the procedures and methods used to construct specific local identities take on particular importance, as do those used by individuals and families to affirm their social position. Through an interdisciplinary team the project seeks to identify the conscious and strategic use of archival and literary sources, and of local antiquities, in methods of self-representation adopted by the elite and by the local communities in the Regno di Napoli between the medieval and early modern period beginning with Campania and then extending to Puglia, Calabria, Lucania, Molise and Abruzzo. The aim of the project is to establish a balanced view of southern continental Italy and to create new instruments which will improve not only international academic knowledge but can benefit civil society as a whole, as well as institutions in laying the foundations for a new conservation strategy to protect and manage the cultural patrimony of southern Italy, a region which has contributed significantly to the formation of a European identity. An accessible database on the Internet will be specifically designed and programmed to gather together all the data from this research pre-requisite for studying such themes, and will provide a new instrument and new prospects of research for scholars world-wide.";1500000;1500000;ERC-2010-StG_20091209;/ERC-SG;UNIVERSITA DEGLI STUDI DI NAPOLI FEDERICO II.;IT;;;/SOC;1;0;0;1;0;0 104737;307494;pcCell;ONG;FP7-IDEAS-ERC;ERC-SG-PE4;FP7;Physicochemical principles of efficient information processing in biological cells;2013-01-01;2017-12-31;;"Biological cellular function relies on the coordination of many information processing steps in which specific biomolecular complexes are formed. But how can proteins and ligands find their targets in extremely crowded cellular membranes or cytosol? Here, I propose that intracellular signal processing depends upon the spatiotemporal order of molecules arising from “dynamical sorting”, i.e. no stable structure may exist at any time and yet the molecules might be ordered at all times. I propose to investigate the existence and the physicochemical driving forces of such dynamical sorting mechanisms in selected neuronal synaptic membrane proteins that must be tightly coordinated during neurotransmission and recovery. To this end, massive atomistic and coarse-grained molecular simulations will be combined with statistical mechanical theory, producing predictions to be experimentally validated through our collaborators. The main methodological challenge of this proposal is the infamous sampling problem: Even with immense computational effort, unbiased molecular dynamics trajectory lengths are at most microseconds for the protein systems considered here. This is insufficient to calculate relevant states, probabilities, and rates for these systems. Based on recent mathematical and computational groundwork developed by us and others, I propose to develop enhanced sampling methods that will yield an effective speedup of at least 4 orders of magnitude over current simulations. This will allow protein-ligand and protein-protein interactions to be sampled efficiently using atomistic models, thus having far reaching impact on the field. The proposed project is at the forefront of an interdisciplinary field, spanning traditional areas such as physical chemistry, computer science, mathematics, and biology. The project claims fundamental advances in both simulation techniques and in the understanding of the physicochemical principles that govern the functionality of the cell";1397328;1397328;ERC-2012-StG_20111012;/ERC-SG;FREIE UNIVERSITAET BERLIN;DE;;;"/PSE;/MAT";1;0;0;1;0;0 104787;299990;PERSEUS;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IEF;FP7;3D modelling of the performance and variability of high electron mobility transistors for future digital applications;2013-02-01;2015-01-31;;"'The current bulk transistor technology will not deliver an ITRS prescribed on-current at and beyond the 22 nm technology generation. A radical change in the device architecture will occur to sustain the device performance and reduce power dissipation. For this reason, Intel has recently announced that they will use a non-planar, 3D Tri-Gate architecture in mass production for the 22 nm technology. In this highly interdisciplinary proposal, we will analyse the feasibility of two novel MOSFETs based on III-V materials channel as future contenders for digital applications. These transistors are Implant Free Quantum Well devices and III-V on insulator FinFETs. Their performance and scalability will be assessed for three technological nodes (22, 16 and 12 nm). We will also study the impact that different sources of intrinsic parameter fluctuations have on their performance and reliability. The effect of the random dopants, gate work-function, oxide or interface charge variability on the threshold voltage, subthreshold slope or on-current of the devices will be evaluated and the impact on circuit design determined. Hierarchical device simulation approaches will be employed, including 2D and 3D Non-Equilibrium Green´s Functions, 2D and 3D Finite-Element Monte Carlo, and 3D Finite-Element Drift-Diffusion simulations. The numerical algorithms implemented in these simulation tools will be optimised and parallelised in order to minimise the computational cost. We will analyse different resolution methods, like Krylov subspace solvers and multigrid techniques, assisted by preconditioners, including domain decomposition methods, which are employed in the solution of the linear systems of equations. The simulation codes will be ported to and optimised for different computational infrastructures, such as high performance computers, Grid and Cloud.'";200371,8;200371,8;FP7-PEOPLE-2011-IEF;/MC-IEF;SWANSEA UNIVERSITY;UK;;;/SCI;1;0;0;1;0;0 93413;237997;SEACOAT;ONG;FP7-PEOPLE;FP7-PEOPLE-ITN-2008;FP7;Surface Engineering for Antifouling - Coordinated Advanced Training;2010-01-01;2013-12-31;;The main research goal of SEACOAT is to improve understanding of biointerfacial processes involved in the colonisation of surfaces by marine fouling organisms. Our vision is that this enhanced understanding will inform the future development of new, environmentally-benign materials and coatings for the practical control of marine biofouling. Our principal objective is to discover which nano- and micro-scale physico-chemical properties of surfaces influence the adhesion of fouling organisms, through the use of surface engineering technologies to fabricate coatings that vary systematically in relevant surface properties, and length scales. We will use advanced surface analytical methods to characterise test surfaces for relevant physico-chemical surface properties and how these change after immersion. Parallel adhesion bioassays using a range of representative marine organisms will test intrinsic antifouling properties of surfaces. The network is an interdisciplinary cooperative of chemists, physicists and marine biologists. Intersectoral aspects unite basic and applied scientists working in universities, a large company and an SME. The project’s S&T objectives will be delivered through research in 4 main Work Packages: viz. WP1-Surface Engineering, WP2-Surface Analytics, WP3-Bioadhesion, WP4- Integration. Two additional Work Packages (WP5, WP6) will be concerned with the Dissemination of project results and the Management of the Network respectively. The aim of the Training Programme is to increase the knowledge base and experience of trainees in each of the Thematic Areas and to develop their transferable skills for future careers in industry or academia. Six training objectives will be delivered through a suite of 7 Core Skills Areas (Research Project, Advanced Training Courses, Project Conferences, International Winter Workshop, Career Development Plan, Generic Research Skills, Transferable Research Skills).;3281108,21;3281108,21;FP7-PEOPLE-ITN-2008;/MC-ITN;THE UNIVERSITY OF BIRMINGHAM;UK;"SuSoS AG;LINKOPINGS UNIVERSITET;RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG;UNIVERSITY OF NEWCASTLE UPON TYNE;UNIVERSITA DI PISA;EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH;INTERNATIONAL PAINT LIMITED";"CH;SE;DE;UK;IT";"/SCI;/EDU";1;0;0;1;0;0 108065;328138;COMBINED MHD AND RT;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IEF;FP7;Magnetohydrodynamics and Radiative Transfer: Development of a combined Solar Prominences modeling technique;2014-01-01;2015-12-31;;"'The project aims to study the physics of solar prominences by coupling together two distinct areas of prominence research - the Magnetohydrodynamic (MHD) Simulations which describe the evolution and structure of prominence magnetic fields and the Radiative Transfer (RT) Modeling which is used to interpret spectroscopic observations of the Sun. This project will integrate these two areas together to construct the first prominence models with realistic MHD processes producing the 3D configuration of the magnetic field within the prominence and non-LTE RT Modeling used to obtain the synthetic radiation emerging from realistically structured prominence plasma. The project combines the expertise of the 'fellow' in RT Modeling with the expertise of the 'researcher in charge' in MHD Simulations in a unique interdisciplinary project aiming to achieve two distinct but complementary goals. First is to generate a new technique for combining idealized but realistic 3D MHD Simulations with RT Modeling which will have wide applicability to the wider Solar Physics community. Second is to apply this newly developed technique to more specific cases of real-world prominences and to compare the obtained configuration of the magnetic field and resulting synthetic spectrum with magnetic field and spectroscopic observations. Accomplishment of these goals will result in a new sophisticated tool with a considerable effect on Prominence Research. The coupling of MHD Simulations and RT Modeling will broaden both research fields and will open new possibilities to study complex issues of Prominence Physics. This project will provide the 'fellow' with expertise beyond his current research field and with extensive set of research, managerial and personal skills which will help him to achieve position of professional maturity. It promotes integration of the European Research Area and reinforces the position of European Solar Physics.'";221606,4;221606,4;FP7-PEOPLE-2012-IEF;/MC-IEF;THE UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS;UK;;;/SCI;1;0;0;1;0;0 107178;331709;GECCCCA;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IIF;FP7;"Genetic encoding and click chemistry with copper-chelating azides for super-resolution imaging of proteins";2013-03-01;2015-02-28;;"'Super-resolution biological microscopy would benefit from a much smaller alternative to green fluorescent protein and enzyme-mediated labelling methods for imaging specific proteins in cells. To facilitate routine tagging of organic fluorophores to cellular proteins for super-resolution imaging, we aim to combine genetic code expansion (the most non-invasive tagging method) with cell-compatible CuAAC with copper-chelating azides (the fastest bio-orthogonal reaction) and extend the utilities of the method to labelling of specific proteins in different subcellular locales, including intracellular. The proposed work here is highly interdisciplinary, combining techniques from synthetic organic chemistry, in vitro evolution of novel protein function, optimizations of protein and chemical functions in mammalian cell context, and super-resolution protein imaging. The work is designed to take advantage of the fellow’s experience in protein labelling, bio-orthogonal chemistry and super-resolution imaging, along with the European host’s proficiency in in vitro evolution and genetic code expansion. The goal is to maximise the mutual transfer of knowledge while obtaining new methodologies and molecular insight into biological systems.'";221606,4;221606,4;FP7-PEOPLE-2012-IIF;/MC-IIF;MEDICAL RESEARCH COUNCIL;UK;;;/SCI;1;0;0;1;0;0 106900;321339;ECOF;ONG;FP7-IDEAS-ERC;ERC-AG-PE5;FP7;Electroactive Donor-Acceptor Covalent Organic Frameworks;2013-03-01;2019-02-28;;The effective conversion of light into chemical or electrical energy is one of the major challenges of humanity during the 21st century. Organic bulk heterojunctions of polymers or aggregates of small molecules combining donor- and acceptor-functionality offer promising prospects for effective light-induced energy conversion. In order to efficiently utilize the solar energy, interpenetrating networks of donor- and acceptor components are often required. While impressive advances have been achieved in organic photovoltaics systems, so far a deterministic control of their nanoscale morphology has been elusive. It would be a major breakthrough to develop model systems with well-defined periodic, interpenetrating networks of electron donor- and acceptor-phases. It is the goal of this project to create such highly defined model systems, to enhance our understanding of the relationship between the electronic and structural parameters and the resulting light-induced charge carrier dynamics. To pursue this challenge, we base our strategy on the recently discovered conceptual paradigm of Covalent Organic Frameworks (COFs). COFs are a class of highly porous, organic crystalline materials that are held together by covalent bonds between molecular building blocks. In a concerted team effort with organic chemists, we will create COFs with different ?-stacked heteroaromatic electron donor- and acceptor moieties, thus forming highly ordered interpenetrating networks for light-induced charge separation. This interdisciplinary program is unique as we join the forces of top-level organic synthesis with advanced nanoscience and in-depth physical characterization in one team.;2431728;2431728;ERC-2012-ADG_20120216;/ERC-AG;LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN;DE;;;"/PSE;/MAT;/IND";1;0;0;1;0;0 91002;235607;CITROVOC;ONG;FP7-PEOPLE;FP7-PEOPLE-IOF-2008;FP7;An assessment of VOC and ozone fluxes in crop plantations from the leaf to the ecosystem level. Relationships with the plant physiology and implications for air quality;2009-07-01;2010-12-29;;Citrus plants are largely grown and economically valuable crops in densely inhabited and polluted Mediterranean areas. Citrus species produce and emit VOC (Volatile Organic Compounds) which enter gas-phase reactions leading to formation of dangerous levels of atmospheric ozone especially in the presence of anthropogenic pollutants. On the other hand, biogenic VOC destroy ozone at leaf level enhancing plant protection against the pollutant. CITROVOC is keyed at understanding the dual role of VOC emitted by Citrus in regulating ozone formation and deposition in Mediterranean areas that are plagued by high ozone episodes. A three-year study, at cellular, whole plant, and ecosystem level, is proposed to understand basic mechanisms leading to ozone interactions with BVOC, to quantify VOC-dependent ozone removal, and to scale up results at community level. Temporal and spatial variations of stomatal ozone uptake, and VOC-induced ozone destruction or ozone formation in the low troposphere will be assessed. The ozone-VOC chemistry will be studied as functions of genetics, phenology, environment, and agricultural practices. The outstanding expertise of the host Institutions, spanning from plant biology to atmospheric chemistry, will allow the applicant to consolidate the strong, interdisciplinary background needed to undertake complex and novel studies about biosphere-atmosphere interactions and their impact on a changing environment. CITROVOC results will usefully complement or upgrade VOC and pollution emission models, contributing to practices and policies for the improvement of air quality and plant protection.;235544,02;235544,02;FP7-PEOPLE-IOF-2008;/MC-IOF;CONSIGLIO NAZIONALE DELLE RICERCHE;IT;;;"/COO;/EDU";1;0;0;1;0;0 88590;227674;QUAGATUA;ONG;FP7-IDEAS-ERC;ERC-AG-PE2;FP7;Quantum Gauge Theories and Ultracold Atoms;2008-11-01;2013-12-31;;"'This is an interdisciplinary proposal which concerns physics of ultracold atoms and quantum information on one side, and high energy and condensed matter physics on the other. The main objectives are: i) to identify experimentally feasible ultracold atom systems that may serve as quantum simulators of, or exhibit physics relevant for some challenging high energy systems and/or quantum gauge theories; ii) to study these ultracold atom systems, their properties and possibilities of control them for applications in quantum information and quantum metrology that go beyond the high energy physics and quantum simulations; iii) to make very concrete experimental proposals of preparation, manipulation and detection of such systems. In particular, it is planned to investigate: A) ultracold atoms in artificial non-Abelian gauge fields, and non-Abelian integer and fractional Hall effects; B) ultracold atoms with Dirac like dispersion relations (as in relativistic field theories and/or graphene in condensed matter); C) ultracold atoms in polymerized geometries, i.e. in lattices of weakly coupled groups of neighbouring sites (plaquettes); D) ultracold gases in frustrated geometries that can mimic quantum spin liquids, that in turn are often described by Abelian discrete gauge theories; E) ultracold gases with 3- or 4-atom interactions that can serve as simulators of Abelian lattice gauge theories; F) the ultimate, but rather risky and speculative objective would be to find the possibilities of realizing quantum simulators of non-Abelian gauge theories, i.e. to identify the dynamical degrees of freedom of 'gluons' and to distinguish them from that of matter fields. Expected results are: i) concrete proposals to simulate quantum gauge theories;, ii) better understanding of quantum gauge theories with ultracold atoms, iii) discovery of novel types of quantum gauge field systems; iv) novel systems for robust quantum information processing and metrology.'";1400000;1400000;ERC-2008-AdG;/ERC-AG;FUNDACIO INSTITUT DE CIENCIES FOTONIQUES;ES;;;"/PSE;/SCI";1;0;0;1;0;0 99030;268800;NEUROSCHEMA;ONG;FP7-IDEAS-ERC;ERC-AG-LS5;FP7;The neurobiology of schemas: knowledge acquisition and consolidation;2011-06-01;2016-05-31;;"This Co-Investigator Application is an interdisciplinary experimental analysis of the neurobiological mechanisms by which we acquire knowledge. Our approach builds on the foundations of contemporary cognitive neuroscience, particularly ideas about the neural mechanisms of declarative memory, and upon recent findings of the participating laboratories (Morris, Fernández) that have each addressed key issues associated with the rapid acquisition and assimilation of new associative information into existing neural ?schemas?. Rapid learning depends upon both novelty and prior knowledge. We propose a coordinated program of research concerning the mechanisms of both determinants. First, we will test that novelty, acting via the release of dopamine, has a direct impact on the mechanisms of cellular consolidation in the hippocampus. Second, with respect to prior knowledge, the retention of new event-related associative information requires the process of systems consolidation within declarative memory, as widely studied, but we further suggest that the organisation of knowledge requires more than just stabilising memory traces within neocortical networks. It also involves the integration of distinct memory traces into neural ?schemas? that, once formed, have a major positive influence on future learning. Our experiments to date are supportive and we outline new research to examine the neurobiological basis of schemas. This will involve animal experimentation including novel behavioural tasks, optogenetics and single-cell recording; and functional magnetic resonance imaging of the human brain using new cognitive tasks combined with pharmacology, transcranial magnetic stimulation, model-free analysis methods, and a translational project reaching into real-world education.";3051404;3051404;ERC-2010-AdG_20100317;/ERC-AG;THE UNIVERSITY OF EDINBURGH;UK;STICHTING KATHOLIEKE UNIVERSITEIT;NL;"/BIO;/LIF";1;0;0;1;0;0 102805;300390;NanoBioMOFs;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IEF;FP7;Nanoscale Metal–Organic Frameworks for Biomedical Applications;2012-03-01;2014-02-28;;"The project NanoBioMOFs (Nanoscale Metal–Organic Frameworks for Biomedical Applications) is a step forward to the researcher’s work undertaken during his postgraduate studies which comprised synthesising bulk Metal–Organic Frameworks (MOFs) for applications in gas storage, gas and liquid separation and molecular sensing. MOFs can be obtained from the connection of metal centres and organic ligands through the space in such a way that the structures obtained can be extended in one–, two– or three–dimensions. The applicant wishes to extend his knowledge in the same research area but from a completely different viewpoint, synthesising MOFs at the nanoscale regime for applications in drug delivery. To date, nanoparticle systems (polymer, iron or gold nanoparticles) have been used as drug delivery agents. This methodology has attracted much attention as it can improve many of the drawbacks of conventional therapy including high doses, rapid clearance, poor pharmacokinetics and strong side effects. Porous MOFs can be also used as drug delivery carriers due to their tunable host–guest properties and the ability to post–modify their internal surface. Although MOFs are excellent candidates to deliver drugs, they cannot be used in the form of traditional bulk but they have to be miniaturized at the nanometre scale. The aim of this project will be the synthesis of known and novel biocompatible, water–resistant MOFs based on biological ligands at the nanoscale, loading of MOFs with anticancer drugs and check their in vitro safety and therapeutic efficacy for chronic diseases such as cancer. This project allows the applicant to conduct truly interdisciplinary and inter–sectoral research, complementing his expertise in synthetic and materials chemistry in nanotechnology (Catalan Institute of Nanotechnology) and biomedicine (Biotechnology and Biomedicine Institute) at laboratories with long–standing collaboration, unique validation models and and state–of–the–art infrastructure.";168896,4;168896,4;FP7-PEOPLE-2011-IEF;/MC-IEF;FUNDACIO INSTITUT CATALA DE NANOCIENCIA I NANOTECNOLOGIA;ES;;;/SCI;1;0;0;1;0;0 87457;204863;EPIFOR;ONG;FP7-IDEAS-ERC;ERC-SG-LS6;FP7;Complexity and predictability of epidemics: toward a computational infrastructure for epidemic forecasts;2008-07-01;2013-12-31;;"The advantage provided by the increasingly interconnected nature of our world has generated a dangerous by-product: the possibility for rapid worldwide spread of epidemics. The ability to forecast epidemic evolution – as much accurately as we can now do for weather conditions – would be of invaluable help in fighting the emergence or re-emergence of viruses such as SARS, avian influenza, HIV-AIDS, Lyme disease, West Nile virus, or more recently the threat of an influenza pandemic. With the advent of interdisciplinary tools and methods, the latest modeling approaches for the study of the spread and control of infectious diseases witness the emergence of a new area of research – computational epidemiology – that integrates mathematical and statistical epidemiology with computational sciences and informatics tools to conduct scenario analysis in public health domain. While few research groups have begun to use large scale simulations for epidemic modeling, many fundamental theoretical questions are left unanswered. How does the complex nature of real world affect our predictive capabilities in the realm of computational epidemiology? What are the fundamental limits in epidemic evolution predictability with computational modeling? How do they depend on the level of accuracy of our description and knowledge of the state of the system? The present project aims at developing a vigorous research effort along two main directions corresponding to i) the formulation of models for the basic theoretical understanding of multi-scale and agent based approaches and their predictive power; ii) the development of computational approaches and data integration tools that will provide a realistic modeling framework for the analysis of observed epidemic outbreaks and the forecast of patterns of emerging diseases. The ERC Starting Independent Researcher Grant offers an ideal opportunity to start a structured program in this direction, aimed at providing fundamental advances in the field.";684000;684000;ERC-2007-StG;/ERC-SG;ISTITUTO PER L'INTERSCAMBIO SCIENTIFICO;IT;;;"/BIO;/LIF;/MED";1;0;0;1;0;0 93289;237922;THROUGHFLOW;ONG;FP7-PEOPLE;FP7-PEOPLE-ITN-2008;FP7;Cenozoic evolution of the Indonesian Throughflow and the origins of Indo-Pacific marine biodiversity: Mapping the biotic response to environmental change;2010-01-01;2013-12-31;;A critical agenda for earth and life sciences is to determine how diverse tropical marine ecosystems such as coral reefs will respond to global environmental change. This will require long-term environmental and ecological data that rarely exist for living coral reefs. In contrast, the fossil record provides abundant examples that can be mined to predict future outcomes. The THROUGHFLOW network will train a cohort of eleven ESRs to enable them to reconstruct past environments and patterns of biotic change using up-to-date technologies within a collaborative interdisciplinary framework. The training program will explore the past record of change on coral reefs in SE Asia in response to reorganization of ocean currents during the Cenozoic. This region contains both the Indo-West Pacific Center of Biodiversity (the most diverse shallow marine ecosystems on Earth) and the Indonesian Throughflow (a primary control of global climate). THROUGHFLOW will reconstruct the history of these two features and develop a model for how coral reefs respond to regional environmental change. Practical training will include eleven integrated research projects and a series of joint training activities to facilitate collaboration and provide access to a variety of expertise. THROUGHFLOW will bring important new data to bear on long-standing scientific controversies, and the results will be relevant to a broad audience including industry and policy makers working to predict and plan for the effects of ongoing anthropogenic environmental change. By providing rigorous training in a range of applied techniques in geology and biodiversity, THROUGHFLOW will produce researchers able to pursue successful careers in academia or industry and will enhance the power of the European research community to tackle pressing issues related to the effects of ongoing environmental change on the biosphere.;2537227,84;2537227,84;FP7-PEOPLE-ITN-2008;/MC-ITN;NATURAL HISTORY MUSEUM;UK;"STICHTING NATURALIS BIODIVERSITY CENTER;UNIVERSIDAD DE GRANADA;CHRISTIAN-ALBRECHTS-UNIVERSITAET ZU KIEL;UNIVERSITAET BREMEN;UNIVERSITEIT UTRECHT;ROYAL HOLLOWAY AND BEDFORD NEW COLLEGE";"NL;ES;DE;UK";"/SCI;/EDU";1;0;0;1;0;0 99047;274575;NFLiquid;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-IEF;FP7;Dynamics and Structure in a Network-Forming Liquid;2012-03-26;2014-03-25;;"This project will study the interplay between structure and dynamics in soft matter. Soft materials are of great practical importance and are ubiquitously present in our daily environment. We will focus on network-forming liquids (NFLs), which are part of the general class of complex fluids characterised by an inherent coupling between their structure and dynamics. NFLs display the strikingly cooperative dynamical behaviour found in many different materials and will be used as a paradigm of complex dynamical behaviour in soft matter. We wish to obtain a microscopic understanding of heterogeneous dynamics, dynamical arrest at the gelation and glass transitions, and nonlinear rheological properties such as shear-thickening, shear-thinning, rheochaos and fracture dynamics. The coupling of structure and dynamics in NFLs suggests that a fundamental link can be made between microscopic mechanisms and complex dynamical behaviour. We will use simulations to study a simple model system, originally devised experimentally, composed of meso-particles in a water solvent linked by polymers. Data can be obtained using advanced numerical simulation techniques, capable of bridging the broad time and length scales involved in this system. A number of different, complementary techniques will be employed including analysis of the potential energy landscape, network analysis and constraint theory, drawing on analogous studies of glassy systems. With this simple model, we will bring together different (and sometimes contradictory) perspectives of slow dynamics in disordered condensed matter, offering a global, coherent microscopic understanding of dynamic heterogeneities and other anomalous dynamical properties in NFLs. This project provides a vital stepping stone for the researcher to forge an independent career, enhancing her research skills with broad interdisciplinary expertise and supporting her career development, through structured training in research and complementary skills.";177380,8;177380,8;FP7-PEOPLE-2010-IEF;/MC-IEF;UNIVERSIDAD DE GRANADA;ES;;;"/EMP;/EDU;/NET";1;0;0;1;0;0 102584;302448;EMLIM;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IIF;FP7;Catalytic Dehydrocoupling/Dehydrogenation of Amine-Boranes: Mechanistic Studies and the Development of Polyaminoboranes, Boron-Nitrogen Analogues of Polyolefins;2012-04-15;2015-10-29;;"Polyaminoboranes [RNH-BH2]n, isoelectronic analogues of the industrially ubiquitous linear polyolefins [RCH-CH2]n , are an exciting class of main-group polymers with potentially interesting properties and applications. These polymers have recently become accessible for a very restricted number of amine-borane substrates. However, key limitations exist in terms of the scope and control of the polymerization. In order to allow the extensive development of this novel polymer system the mechanism of the metal-catalysed polymerization needs to be probed and understood and the design of new catalysts thereby enabled. This proposal aims to exploit the experience of Dr. Erin Leitao in elucidating mechanisms and catalyst design, which she gained during her Ph.D. in a leading research group in Canada, to allow the development of polyaminoboranes. The proposed research will also take advantage of the experience of the host, Prof. Ian Manners at the University of Bristol, UK, in the areas of boron-nitrogen molecules and polymers, and polymer and materials science. Thus, embedding Dr. Leiteo in Prof. Manners lab will lead to mutually beneficial interactions and will permit the project’s ambitious goals to be met. The proposal is both interdisciplinary and multidisciplinary in nature, and involves aspects of synthetic main group chemistry, mechanistic chemistry, catalytic chemistry, main group polymer chemistry, and polymer and materials science. The project will significantly enhance Europe’s position in the fields of i) energy and ii) materials and new production technologies, which are recognized as important strategic areas. After the applicant’s fellowship is over, she plans to return to North America to take up an academic position at a top university in Canada.";200371,8;200371,8;FP7-PEOPLE-2011-IIF;/MC-IIF;UNIVERSITY OF BRISTOL;UK;;;/SCI;1;0;0;1;0;0 103622;302425;MIGPRO;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IEF;FP7;Beyond cynicism and bare life: practices of citizenship against migrants' inclusive exclusion;2012-07-23;2014-07-22;;"'The proposed research addresses themes of current social relevance, such as the politics of migration and its governance, and their relation to emerging forms of engaged citizenship and sovereignty. The researcher shall investigate ethnographically modes of protest and solidarity that seek to contrast states' regulation of migrant movement (with a special focus on detention and deportation), and labour regimes based on the disposability of migrant bodies in contemporary Europe. Forms of resistance and flight are widespread across different EU countries, and take the form of attempted escapes from detention centres, hunger strikes, dirty protests, the sowing of one's lips, and episodes of self-harming, as well as labour strikes and dramatic acts that capture media attention, such as the occupation of rooftops and the climbing of cranes. Anti-racist solidarity networks are also active in supporting undocumented migrants, through demonstrations, boycotts, and the provision of alternative media coverage on the issue. The research will take Italy as the main research location, but a comparative perspective will be brought into the project by creating an interdisciplinary research network gathering scholars who work on related issues across Europe. The project will investigate the relationship between subjective experiences of migration, detention, protest and solidarity, in the light of multiple historical trajectories and personal narratives. Affective and intimate relations will be explored together with the workings of institutions and structures of power, their limitations and possible alternative modes of sociality.'";185763,6;185763,6;FP7-PEOPLE-2011-IEF;/MC-IEF;ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA;IT;;;/SCI;1;0;0;1;0;0 103911;300146;WoW: Radio Bari;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IEF;FP7;“War of Waves”. European Radio Propaganda in the Arab World: the Experience of Radio Bari (1934-43);2012-09-01;2014-08-31;;"This project deals with the radio propaganda that Italy, Great Britain, France and Germany carried out in the Arab world between the mid-1930s and the early 1940s. In particular, it focuses on Radio Bari (1934-43), the first radio station to broadcast in Arabic with the purpose of courting the Arabs and challenging the French and British colonial power. This topic has attracted scholarly interest but as of yet has not been addressed thoroughly. My research is the first one to tackle this issue in its entirety, with the aim of shedding light on such a neglected page of history. My project has three main objectives. (I) Reconstructing the main elements of Radio Bari—its structure, its programs, and its main actors—according to two theoretical and historiographical frameworks: the use that the Fascist totalitarian regime made of the instruments of modern propaganda in order to exert its control over the population; the Fascist foreign policy’s employment of a tool of “soft power” aimed at transforming the Mediterranean sea into a mare nostrum and expanding the Italian presence in the Arab world. (II) Exploring Radio Bari as a cultural and transnational experience by examining the Orientalist and anti-Semitic messages in its programs, and by enquiring into what extent it might be considered an example of transnational networking between Europe and the Arab world. (III) Investigating the two phases of the “war of waves”, the first one that took place in 1938-39 and the second one that was waged during WWII. In terms of methodology, being as my research is at the crossroads of different disciplines—history of international relations, cultural history, colonial history, transnational history, history of media—I will employ an interdisciplinary approach. In terms of sources, in addition to existing literature, my research will be based on extensive unpublished documentation from Italian, Vatican, British, French, Moroccan, Israeli, Egyptian, and American archives.";249911,6;249911,6;FP7-PEOPLE-2011-IEF;/MC-IEF;EUROPEAN UNIVERSITY INSTITUTE;IT;;;/SCI;1;0;0;1;0;0 104619;316736;IMPACT;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-ITN;FP7;Innovative Modelling for Pharmacological Advances through Collaborative Training;2013-01-01;2016-12-31;http://www.csr-impact.eu;"This project forms an interdisciplinary collaborative partnership between AstraZeneca (AZ, Sweden) and the University of Warwick (UoW, UK) to train Early Stage Researchers (ESRs) in systems modelling tools and techniques enabling them to perform research projects at the forefront of international pharmacokinetic (PK) and pharmacodynamic (PD) analysis. This project will build upon extremely strong research and training links already formed between the UoW and AZ (UK) in PK/PD modelling and will support the clearly identified need within AZ worldwide to train more personnel with high-level skills in systems modelling for future drug development. The most effective drugs are those that produce clinical benefit by modulating disease biology and are given to patients at an optimal dose and schedule. In order to deliver new drugs it is necessary to quantify, translate and simulate from the test tube to the patient. This includes being able to model biological pathways, quantify relationships between dose/exposure, target engagement, efficacy and safety in pre-clinical tests and humans and utilising all relevant information efficiently and quantitatively. The development and application of innovative modelling techniques to tackle current problems in drug development allied to the training of researchers with skills to perform these tasks are key drivers for the partners. A unique blend of multidisciplinary training will be offered to the ESRs by both partners through well-established, extensive and innovative programmes at their sites with the appointed ESRs registered for PhDs at the UoW. The ESR projects will be based on research problems and data generated at AZ. The outcomes of the projects will not only maintain the positions of AZ and the UoW at the forefront of international research in PK/PD analysis, but also greatly enhance the EU’s standing worldwide in this area, whilst also enhancing the future job prospects of those trained within the AZ group worldwide";1467958,8;1467958,8;FP7-PEOPLE-2012-ITN;/MC-ITN;THE UNIVERSITY OF WARWICK;UK;ASTRAZENECA AB;SE;/LIF;1;0;0;1;0;0 90915;220754;INCA;ONG;FP7-PEOPLE;PEOPLE-2007-2-1.IEF;FP7;Investigating Neutrinos in Cosmology and Astrophysics;2009-12-01;2011-11-30;;We propose to explore the role of neutrinos in cosmology and astrophysics via theoretical investigations and the development of numerical and computational tools. In the first case, we shall investigate further the phenomenology related to the cosmological neutrino mass and energy density determination, exploiting the forthcoming data from the Planck ESA satellite and other cosmological surveys and probes. Particular attention will be devoted to the cosmological impact of new physics in the neutrino sector. In the second case, we shall consider the high and ultra-high energy sector of relevance for Cherenkov detectors (like the ongoing effort towards a Mediterranean km3 telescope) and Ground Arrays like the Pierre Auger Observatory. An interdisciplinary and multi-messenger approach will be the common denominator in both cases: in the former field, we shall consider the implications from (and the consequences for) laboratory experiments like Katrin or neutrinoless double beta decay searches, as well as hints of new physics that could come from the first results of the Large Hadron Collider (LHC). In the latter sector, we will link the predictions for the neutrino-related observables at high energy with cosmic ray and gamma-ray data (from instruments like Auger, HESS, MAGIC and GLAST). Incursions in the intermediate energy ranges (MeV) are possible, especially related to the phenomenology of solar and core-collapse supernova neutrinos, and to the development of European plans towards a large underground facility for neutrino-related studies.;143204,12;143204,12;FP7-PEOPLE-2007-2-1-IEF;/MC-IEF;AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS;ES;;;"/SCI;/EDU";1;0;0;1;0;0 105813;318053;SMARTCANCERSENS;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IRSES;FP7;Micro/nanosensors for early cancer warning system - diagnostic and prognostic information;2013-01-01;2016-12-31;;'Oncologists still rely heavily on biological characterisation of tumours and a limited number of biomarkers which have demonstrated clinical utility. Routine cancer diagnostic tools may not be always sensitive enough and may only detect proteins at levels corresponding to an advanced stage of the disease. Recently, new genomic and proteomic molecular tools (molecular signatures) are being employed which include genetic and epigenetic signatures, changes in gene expression, protein profiles and post-translational modification of proteins. Such advanced diagnostic tools are not always readily adapted to clinical cancer screening due to their complexity, costs and the requirement for highly-qualified operators. Novel bioanalytical methodologies for detection of specific biomarkers/ biomolecules, based on nanostructured electronic sensors (rapid, sensitive devices capable of miniaturisation and deployment on site or in small clinics), fulfill the necessary requirements and have the potential to compliment time- and labour consuming clinical analysers used in medical laboratories currently. The primary objective of this proposal, therefore, is to gather together an international and interdisciplinary consortium of ten research teams from EU Member States, Third (including ENP) countries with EU agreements on S&T, in order to share and jointly exploit knowledge and expertise in the development of micro/nanosensors as tools in early cancer diagnosis. A key scientific target is the realisation of intelligent electronic devices which respond to biomolecules such as formaldehyde, amines, metal ions, saccharides, activities of amine oxidases, arginase and glutathione-S-transferase. This will entail design, development and characterisation of nano-scale transducers suitable for testing in clinical samples.';584800;584800;FP7-PEOPLE-2012-IRSES;/MC-IRSES;INSTITUTE OF TECHNOLOGY TALLAGHT;IE;"UNIVERSITAT ROVIRA I VIRGILI;LINKOPINGS UNIVERSITET;UNIVERSITE LYON 1 CLAUDE BERNARD;UNIVERSITATEA DIN BUCURESTI;UNIVERSIDADE DE COIMBRA";"ES;SE;FR;RO;PT";/SCI;1;0;0;1;0;0 97569;267746;MOLNANOMAS;ONG;FP7-IDEAS-ERC;ERC-AG-PE3;FP7;Molecular Nanomagnets at Surfaces: Novel Phenomena for Spin-based Technologies;2011-01-01;2015-12-31;;Molecular nanomagnets, also known as Single Molecule Magnets (SMMs), are a class of molecules that at low temperature exhibit magnetic hysteresis of pure molecular origin and not related to a cooperative effect. In the past fifteen years they have attracted great interest for their potentiality to act as magnetic memory units and for the many quantum effects in the dynamics of their magnetization. Recently our observation that the magnetic bistability is retained when a tetranuclear iron(III) molecular cluster is grafted to a metallic surface has renewed the interest in these materials, which appear the ideal candidates for fundamental investigations on the interplay between conducting electrons and magnetic degrees of freedom in the emerging field of molecular spintronics. In this project we plan to benefit from our leading position in the research on SMMs to explore novel phenomena originated by the combination of SMMs with conducting and magnetic substrates in hybrid structures. Our interdisciplinary approach starts from the design and synthesis of SMMs and includes their assembling on surface from solution or in high vacuum as well as the tuning of the interaction with conducting, and magnetic substrates through chemical tuning of SMMs. We will focus on the quantum dynamics of the magnetization that seems particularly affected by the interaction with a magnetic substrate opening perspectives for novel spintronic devices and for an unexplored strategy to increase the blocking temperature of SMMs. Additional aspects will be investigated, in particular the use of switchable magnetic molecules as well as the possibility to modify the interface with yet unexplored approaches, for instance exploiting the magnetic torque on molecules with large magnetic anisotropy.;2269200;2269200;ERC-2010-AdG_20100224;/ERC-AG;UNIVERSITA DEGLI STUDI DI FIRENZE;IT;;;"/PSE;/ELM;/NNT";1;0;0;1;0;0 100191;293643;BIONANOMUTT;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-CIG;FP7;Multi-compartmental Biomolecular Nanocarriers for Multi-modal Targeted Therapies;2011-10-01;2015-09-30;;Nanomedicine is an interdisciplinary field of research that aims to use nanotechnology to improve the pharmacokinetic profile of therapeutics and/or the contrast and information from medical imaging and diagnostics. The advances in medical treatments that nanomedicine strategies will provide will have a significant socioeconomic impact for the E.U. and is particularly timely due to the aging populations in E.U. member states. This work will use a multi-strategy approach to design novel multicompartmental, multifunctional nanoarchitectures for nanomedicine applications. Lipid nanodiscs will be evaluated as a novel hydrophobic drug carrier and the versatility of the scaffold protein for these discs will be explored by assessing its capacity to form similar complexes with synthetic block copolymers. Multicompartmental, size-limited nanostructures will be developed by using the self-organisation of functional amphiphiles into anisotropic subunits as building blocks for superstructures of greater complexity and functionality. The basic building blocks explored will consist of liposomes, polymersomes and hydrid lipopolymersome structures as well as protein-stabilised lipid nanodiscs. This project will also explore incorporating quantum dots into these nanoarchitectures as an added imaging modality. Finally, through multidisciplinary collaboration of basic scientists through to clinicians, an adjuvant nanomedicine therapy will be developed for treatment of superficial bladder cancers. These therapeutic nanoparticles will contain therapeutic, imaging and active targeting functionalities to remove residual malignant cells following the surgical resection of tumours.;100000;100000;FP7-PEOPLE-2011-CIG;/MC-CIG;UNIVERSITY OF LEEDS;UK;;;/SCI;1;0;0;1;0;0 102377;301678;UEDIN-DSZ-BIO;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IEF;FP7;Synthesis and Biological Target Identification of the Potent Tubulin Inhibitor Disorazole C1 and Novel Heterocyclic Analogues;2012-09-17;2014-09-16;;"'Cancer is a common and life-threatening disease with world-wide occurrence, and the number of affected individuals and morbidity continues to increase annually. It is therefore of great importance that straightforward syntheses of potential anti-cancer agents are developed in order to advance treatment and drug discovery in this field. The disorazoles, the subject of this proposal, are a group of natural products which display strong anticancer activity against a variety of cell lines, including multidrug resistant cells. Although one total synthesis and several approaches have been published towards the key family member disorazole C1, these are lengthy and poor-yielding. Consequently, a more-detailed investigation of the mode of action of this highly potent tubulin inhibitor has been severely hampered. The synthetic approach outlined in this proposal will dramatically increase the convergency of synthesis and will allow us to explore how changes in one of the key structural features affects the natural product structure and function. Working in the Hulme group laboratories, the Fellow will synthesise the disorazole C1 analogues with a pioneering approach to construction of the macrolactone core. Using computational modelling and a range of traditional and cutting-edge technologies (X-Ray, NMR and IM-MS) he will study the analogues' structures and tubulin-binding abilities. The Fellow will conduct biological tests including cell-based assays in-house, exploiting the world-leading expertise and facilities within EaStCHEM. The project is thus ideally placed to offer the Fellow a broad interdisciplinary training and give him new insights into both traditional and modern chemical biology and medicinal chemistry techniques. He will attend a series of training courses, tutor and lecture to undergraduates, and exercise considerable supervisory responsibility within the research group; thus enhancing his long-term prospects of becoming an independent academic researcher.'";209033,4;209033,4;FP7-PEOPLE-2011-IEF;/MC-IEF;THE UNIVERSITY OF EDINBURGH;UK;;;/SCI;1;0;0;1;0;0 107838;330516;NPS4FM;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IIF;FP7;Nanomaterial Photonic Sensors for Food Manufacturing;2014-02-10;2016-02-09;;"The ultimate goal of the project is to generate and transfer knowledge on the development of new nanomaterials specifically applicable in novel macro-bacterial sensors for food manufacturing and processing industry. The special structure of nanomaterials gives rise to their amazing properties. The ability to manipulate the structure and composition on the nanoscale provides very large opportunities to create new materials with superior performance for new products and devices. Since the optical properties of nanomaterials can be controlled by changing their size, shape, and aspect ratio, as well as via their surface modification, nanomaterials are prime candidates as building blocks for photonic sensors. The overall objective of this research is to develop the synthesis of ZnO, ZnS and PbS nanostructures with different sizes and morphologies via the laser ablation in liquid technique, then to modify and functionalize the surfaces of the prepared nanostructures and finally to use them for the preparation of photonic sensors with bacteria-detecting properties. Such efficient, easy-to-use and rapid sensors will be evaluated within different food processing, weighing and packaging lines available from project partner. This is an ambitious research programme, with a strong interdisciplinary nature combining materials engineering, surface science, bio-engineering, physics, chemistry and soft matter science. Its success is underpinned by the combination of complementary expertise of the Fellow, Host and Partners in nanomaterial preparation and characterization, photonics and food processing and analysis, respectively. The project will have a positive impact on a longer shelf-life of ready food, monitoring of food manufacturing lines, and optimization of cleaning routine during food manufacturing and packaging. Hence, positive impact on public health sector, as well as economic and ecological effects, is expected.";309235,2;309235,2;FP7-PEOPLE-2012-IIF;/MC-IIF;ASTON UNIVERSITY;UK;;;/SCI;1;0;0;1;0;0 103123;300071;NeMPSIA;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IIF;FP7;Neutrons for Membrane Protein Structure, Interactions, and Assembly;2012-03-01;2013-02-28;;"Understanding membrane protein structure, interaction between these proteins and lipids, and how membrane proteins assemble in the membrane are as of yet unsolved problems of structural biology. This proposal aims to further our understanding in these areas by uniquely combining structural and biophysical data obtained from nuclear magnetic resonance experiments (Straus` area of expertise) with neutron methods, such as small angle neutron scattering (SANS), reflectometry, and neutron diffraction (Forsyth`s and other ILL members` area of research). Specifically, the team will focus their attention on three areas: 1) membrane perturbing antibiotic structure; 2) interaction of lipopeptides with the essential bacterial cell wall biosynthesis component lipid II; and 3) the assembly of membrane proteins in lipids, as studied using the tractable system of B5 filamentous bacteriophage. The proposed projects will not only enable Straus to expand her repertoire in structural methods by exposing her to a host of neutron methodology, but will also cement a strong partnership between Canada and France. The projects will also involve the close collaboration of a number of research groups in France and Germany: the group of Michel Gauthier in Nantes, a leading expert in B5 filamentous bacteriophage and the group of Hans-Georg Sahl in Bonn, who have worked extensively on characterizing interactions between lipopeptides and lipid II. The interdisciplinary nature of the proposed work and the strength of the team will ensure success on all fronts.";83885,7;83885,7;FP7-PEOPLE-2011-IIF;/MC-IIF;INSTITUT MAX VON LAUE - PAUL LANGEVIN;FR;;;/SCI;1;0;0;1;0;0 107894;328862;CRAFTS;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IEF;FP7;Crafting networks in early farming societies: tracing the residues of Neolithic activities through the study of stone artefacts;2013-10-01;2015-09-30;;"This project investigates a key research question in the study of many different societies: how do changing strategies and technologies of production constrain and shape social relations? This question will be addressed by investigating the role of technology in the development of social networks in early farming societies using an interdisciplinary research strategy that integrates stone tool analysis and functional analysis with a wide range of other inorganic and organic materials. The Neolithic period has been chosen to explore this issue because it represents a crucial phase in human history characterised by diverse technological and social changes. A crucial step in understanding the technological and social networks that structured the life of Neolithic communities is to establish the nature, range and social context of craft and food-processing activities taking place within Neolithic settlements. Three archaeological sites of critical importance for the Neolithic of Europe are chosen as case studies (Çatalhöyük, Knossos, Makriyalos). The character of activities will be established scientifically through the application of state-of-the-art analytical techniques, principally microwear and residue analysis techniques. Central to this project is the integration of scientific approaches with a broader theoretical framework for understanding technological acts, cross-craft interactions and contexts of social interaction in Neolithic communities. The primary objective of the IEF project is for the applicant to develop new and highly specialised scientific training in microscopic analysis techniques at the world-leading Laboratory for Artefacts Studies in Leiden. The proposed research will allow for the development of new collaborations between the host institution in the Netherlands and other institutions in Britain, Greece and Turkey. Training received through the IEF project will enhance the applicant’s scholarly status and lead to professional maturity.";183469,8;183469,8;FP7-PEOPLE-2012-IEF;/MC-IEF;UNIVERSITEIT LEIDEN;NL;;;/SCI;1;0;0;1;0;0 101728;272653;DICEM;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-IEF;FP7;Diffusion of Ions in Cementitious Materials;2011-09-01;2013-02-28;;'Durability and reliability of concrete infrastructure is a serious, large scale, financial and safety concern with an increasing scientific, engineering and economical focus. Although the interest for numerical modelling of cementitious materials and durability issues increases rapidly in recent years, a comprehensive knowledge on their fundamental processes is still lacking. The proposed project is interdisciplinary, bridging fundamental understanding of multiphase ionic transport in porous materials and durability based design of cementitious materials that combine computational materials science, chemistry, physics and engineering technology. The influence of the morphological effect and the level of water saturation on the ionic diffusion properties of hydrating cement pastes will be investigated using the TU Delft's HYMOSTRUC cement hydration and microstructure development model. The diffusive properties of the simulated microstructures will be analyzed by a number of developed numerical 3D network methods. These innovative numerical 3D network models will be coupled with another developed numerical code, called MultIDiff, to describe the multi-component ionic diffusion in concrete structures considering the time and space dependency of parameters. This project will advance the quality of European science, relative to the North America (USA and Canada) and Japan, in the field of numerical tools to predict durability of cementitious materials. As both institutions: the host’s, TU Delft and the fellows, University of Zagreb are actively involved in industry related projects to predict the service-life of new and existing concrete structures, the results of this project will find a direct industry application. The design based on a sound quantitative basis will make cement and concrete a more environmentally friendly, sustainable and affordable material.';134255,6;134255,6;FP7-PEOPLE-2010-IEF;/MC-IEF;TECHNISCHE UNIVERSITEIT DELFT;NL;;;"/EMP;/EDU;/NET";1;0;0;1;0;0 100655;277742;PASCAL;ONG;FP7-IDEAS-ERC;ERC-SG-ID1;FP7;Probabilistic And Statistical methods for Cosmological AppLications;2011-11-01;2016-10-31;;"This is an interdisciplinary project at the interface between Mathematical Statistics, Probability and Cosmological Applications. The principal focus is on the harmonic analysis for isotropic, mean square continuous spherical random fields, with a view to applications to Cosmic Microwave Background radiation data analysis. We will focus in particular on the following issues: 1) the characterizations of isotropy in harmonic space, the analysis of higher order polyspectra and their applications to non-Gaussianity analysis; 2) the constructions of spherical needlets/wavelets and their stochastic properties; 3) the analysis of random sections of spin fiber bundles on the sphere, as motivated by the analysis of CMB polarization and weak gravitational lensing 4) adaptive density estimation for directional data, as motivated by Cosmic Rays data analysis.";1193000;1193000;ERC-2011-StG_20101014;/ERC-SG;UNIVERSITA DEGLI STUDI DI ROMA TORVERGATA;IT;;;/SCI;1;0;0;1;0;0 103393;301465;AnthroSOIL;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IEF;FP7;Signatures in Anthropological SOILs: Developments for the identification of activities associated with daily life;2012-09-01;2014-08-31;;"If the human uses of soils are profoundly different, can these use histories be deduced from their chemical traces? Using the potential of organic biomarkers, AnthroSOIL will assess spatial organisation of prehistoric dwellings in order to recognise daily life activities through soil organic matter analysis. At the interface of archaeology and chemistry, the project aims to develop a new methodological approach for the organic analysis of palaeosoils. State-of-the-art methods and cutting edge technology in organic residue analysis will be assessed and used to characterise and to map the organic content of soil (elemental analysis, PyGC & ultrafast-GC, LC-MS/MS, GC-MS/MS, GC-c-IRMS, MALDI imaging, ZooMS, starch analysis).The project will investigate activity patterns within Stonehenge World Heritage site by an extensive study of the Late Neolithic settlement of Durrington Walls a short-lived but large village probably inhabited by the builders of Stonehenge. Durrington Walls present a unique opportunity to examine activities across one of Europe’s finest and most well excavated prehistoric sites. The project will benefit of a remarkable concentration of expertise at the University of York (UK), within BioArch, an inter-disciplinary research centre dedicated to work on biomolecular archaeology, an emerging European research strength. I will work in state-of-the art facilities with world-leading scientists in bioarchaeology for the joint development of archaeological soil studies. The broadening of my skills and perspectives through the combination of a broad range of analytical techniques in lipids, proteomic and stable isotopic to study prehistoric daily life, will place me in an excellent position to exploit new opportunities in biomolecular archaeology research and enhance my interdisciplinary career perspective.";209033,4;209033,4;FP7-PEOPLE-2011-IEF;/MC-IEF;UNIVERSITY OF YORK;UK;;;/SCI;1;0;0;1;0;0 106236;321426;Relex-Agencification;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-CIG;FP7;Agencies in EU Foreign Policy: RELEX-Agencification;2012-10-01;2016-09-30;;This project examines a widespread, yet under-researched, trend in European politics, namely the transformation of EU foreign policy through processes of ‘agencification’. In what can be seen as a revolutionary move, an ever increasing number of European foreign policy tasks are being delegated to European agencies – that is, specialised and ‘depoliticised’ administrative structures – or, in other words, bureaucrats are increasingly becoming diplomats. Amongst many important questions, it is necessary to understand the causes and the consequences of such delegation of foreign policy tasks to European agencies. The project analyses this transformation process at the European Union (EU) level, using an original interdisciplinary analytical framework. It does so by focusing on the traditional core of foreign policy, which concerns security in both its internal and external dimensions. Therefore, at the EU level, 14 agencies and agency-like bodies dealing with security matters will be examined. As this process of delegation of an increasing number of foreign policy tasks to European security agencies, which has many potential important consequences, has received very little attention to date, the Research Fellow (RF) expects to generate significant findings that will have a major impact on academic and policy debates. In addition to much needed new empirical data on this process of agencification and its impact on EU foreign policy, the project will open up new theoretical horizons by building up bridges between rational choice and constructivist approaches.;100000;100000;FP7-PEOPLE-2012-CIG;/MC-CIG;UNIVERSITY OF DUNDEE;UK;;;/LIF;1;0;0;1;0;0 104219;321822;DYNASTIIC;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-CIG;FP7;Dynamic Signal Transduction in Individual Cells;2012-08-01;2016-07-31;;"Regulation of proliferation and differentiation is a fundamental challenge for multicellular organisms. The decision between alternative cell fates is therefore tightly controlled by cellular signaling. During the past decades, the central components of the signaling machinery have been identified. The challenge we are facing now is to understand how signaling networks act dynamically in living cells and how they intersect with each other to control the physiological response of a cell. Since signaling networks contain complex, non-linear interactions that are difficult to understand intuitively, it will be important to use an interdisciplinary approach, combining quantitative experiments and theoretical analysis. As cellular decisions often vary even in genetically identical cells depending on the initial conditions and the micro-environment, we have to measure signaling on the level of individual cells. In the proposed project, we will investigate the TGFbeta pathway, a central growth-inhibitory pathway in epithelial cells. We will acquire quantitative data with high temporal and spatial resolution using time-lapse microscopy of live fluorescent reporter cells and combine it with mathematical modeling. Using this approach, we will determine how the structure of the network shapes its dynamic response, how activation of the signaling pathway is translated into changes in cellular physiology and how TGFbeta interacts with other networks to control cell fate. The resulting mechanistic understanding will enable us to manipulate cell decisions in-vivo and develop therapeutic interventions to regain control over aberrant signaling processes diseased cells. After a postdoc at Harvard Medical School, the applicant is moving back to Europe to start a career as an independent researcher in Germany. Funding of the proposed research will provide significant support for the reintegration process and will foster the transfer of knowledge to the European research community.";100000;100000;FP7-PEOPLE-2012-CIG;/MC-CIG;TECHNISCHE UNIVERSITAT DARMSTADT;DE;MAX-DELBRUCK-CENTRUM FUR MOLEKULAREMEDIZIN;DE;/LIF;1;0;0;1;0;0 92869;225634;L4S;ONG;FP7-SECURITY;ICT-SEC-2007-1.0-02;FP7;Learning 4 Security;2009-07-01;2011-07-31;http://www.L4S-project.info;Effective collaboration dynamics are at the core of crisis management in the transportation sector. Nevertheless, in today’s global environment, a very large number of crisis management initiatives fail to deliver the value expected, as the collaboration challenges in crisis are very high. This is because of the complexity of the knowledge integration processes as well as the diversity and distributed nature of the people, groups and knowledge involved in the management of crisis under high pressure of time. Thus, effective crisis management requires collaborative crisis management competencies at the individual, team, organizational as well as the inter-organizational level. The project builds on interdisciplinary scientific / academic models and best / worst practices and experiences to identify the factors inhibiting effective collaboration in crisis situations in the transport sector (“Collaboration Traps & Challenges in Crises”), and the interventions required to reduce these risks (“Collaborative Crisis Management Competencies”). After integration, this know-how will lead to the development of: • An innovative framework (Advanced Collaboration in Crisis Management – ACCM-Framework), addressing the effective development of collaboration competencies for the specific challenges of crisis management in the transportation sector. • A set of widely deployable, advanced, interactive and experiential technology-enhanced solutions (“ACCM Simulation Games”) guaranteeing the effective understanding and internalization of collaborative decision making processes (1) under extreme time pressure, (2) facing the lack and asymmetries of information, (3) dealing with the diversity and emotions of people, and (4) effectively addressing the interpersonal dimension of speed-relationship building, trust and role definitions between crisis managers in the transportation industry.;3471413,41;2415768,13;FP7-ICT-SEC-2007-1;/CP-FP;DELOITTE BUSINESS SOLUTIONS ANONYMI ETAIREIA SYMVOULON EPICHEIRISEON;EL;"ATHENS INTERNATIONAL AIRPORT S.A.;ATHENS LABORATORY OF BUSINESS ADMINISTRATION;ALPHALABS SARL;FREQUENTIS AG;FVA SAS DI LOUIS FERRINI & C;AKAD Wissenschaftliche Hochschule Lahr GmbH;CREUERS DEL PORT DE BARCELONA SA;UNIVERSITAET DER BUNDESWEHR MUENCHEN;OSTERREICHISCHE STUDIENGESELLSCHAFTFUR KYBERNETIK VEREIN;UNIVERSITA CATTOLICA DEL SACRO CUORE";"EL;FR;AT;IT;DE;ES";/ICT;1;0;0;1;0;0 98421;271578;EtoileCascadesIdeas;CLO;FP7-ICT;ICT-2009.8.0;FP7;Enhanced Technology for Open Intelligent Learning Environments;2011-02-01;2014-05-31;;Complex systems science is highly interdisciplinary. The silo-based education provided by most universities creates scientists expert in one discipline but ignorant of most others. Most PhD programmes require students to learn key ideas from other disciplines relevant to their topic, but knowledge across the community is patchy. This includes basic social science and even the core disciplines of mathematics, statistics, physics and ICT. The Complex Systems Society (CSS, 2000\ members) has identified this as a major hindrance to the development of the science.
We will develop and use a remarkable new way of automatically creating educational resources. It is scalable so that the cost of educating large numbers of students is very low. It is adaptive to changes in the curriculum in fast-moving research fields creating new learning resources as new topics emerge, and it is adaptive to students by creating learning resource that reflects their personal styles of learning, background knowledge, and language. Étoile is a big step towards personalised learning.
The basic étoile concept is simple but a demonstrator is needed to show that the idea works in practice for real students working towards masters and doctoral degrees. We will provide an open source implementation for use by the CSS, and other organisation needing to disseminate new ideas quickly at low cost to a heterogeneous community.
Following proof of concept, the CSS will take étoile forward in its long term programme of professional training and recognition. Students with certificated mastery of the core curriculum will be highly attractive as post-docs. As mastery of the core curriculum becomes common communication in the research community will be much easier, there will be less duplication of effort and more cross-fertilization of ideas. Étoile can have big and long-lasting impact on the science of complex systems, and the method can be adopted by other fast-moving research communities.;672314;599480;FP7-ICT-2009-C;/CSA;THE OPEN UNIVERSITY;UK;"FUNDACAO DA FACULDADE DE CIENCIAS DA UNIVERSIDADE DE LISBOA FP;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS";"PT;FR";"/SCI;/ITT";1;0;0;1;0;0 101227;278065;LONGWOOD;ONG;FP7-IDEAS-ERC;ERC-SG-ID1;FP7;Long-term woodland dynamics in Central Europe: from estimations to a realistic model;2012-01-01;2016-12-31;;"The vegetation of Central Europe has been directly influenced by humans for at least eight millennia; the original forests have been gradually transformed into today’s agricultural landscape. However, there is more to this landscape change than the simple disappearance of woodland. Forests have been brought under various management regimes, which profoundly altered their structure and species composition. The details of this process are little known for two main reasons. The greatest obstacle is the lack of cooperation among the disciplines dealing with the subject. The second major problem is the differences in spatio-temporal scaling and resolution used by the individual disciplines. Existing studies either concern smaller territories, or cover large areas (continental to global) with the help of modelling-based generalizations rather than primary data from the past. Using an extensive range of primary sources from history, historical geography, palaeoecology, archaeology and ecology, this interdisciplinary project aims to reconstruct the long-term (Neolithic to present) patterns of woodland cover, structure, composition and management in a larger study region (Moravia, the Czech Republic, ca. 27,000 km2) with the highest spatio-temporal resolution possible. Causes for the patterns observed will be analyzed in terms of qualitative and quantitative factors, both natural and human-driven, and the patterns in the tree layer will be related to those in the herb layer, which constitutes the most important part of plant biodiversity in Europe. This project will introduce woodland management as an equal driving force into long-term woodland dynamics, thus fostering a paradigm shift in ecology towards construing humans as an internal, constitutive element of ecosystems. By integrating sources and methods from the natural sciences and the humanities, the project will provide a more reliable basis for woodland management and conservation in Central Europe.";1413474;1413474;ERC-2011-StG_20101014;/ERC-SG;BOTANICKY USTAV AV CR, V.V.I.;CZ;;;/SCI;1;0;0;1;0;0 99242;269608;RESOCEA;ONG;FP7-IDEAS-ERC;ERC-AG-SH6;FP7;Regime and Society in Eastern Europe (1956 - 1989). From Extended Reproduction to Social and Political Change;2011-06-01;2016-05-31;;"'The ambition of this project rests on the long-established tradition of the comparative politico-historical and interdisciplinary studies of the totalitarian regimes and on the theoretical efforts to elucidate the social dynamics and social change in Eastern Europe during the so called 'real socialism'. It will deal with the relations between regime and society in an attempt to highlight the growing tensions between them. Without neglecting the important role of the geopolitical confrontation and the dissident movements, this work will search the key factors for the disintegration of communist societies in the common peoples’ modes of conduct. While the regime followed the same guiding principles till its end, individual and community ways kept changing and these shifts affected the whole society. Therefore we should study and critically analyse the evolving motives behind individual and group everyday behavior, their new moral orientations, as well as the changes in the regime practices and the characteristics of the dominant type among party functionaries. The communist regime loses support among social groups, which it favours and considers its social basis. The project involves one PI who will organise and supervise the work of four senior researchers from the ex-socialist countries while each of them deals with the local aspects of the issue. The PI will study these phenomena in Bulgarian context and at the same time will provide a comparative narrative linking all five case studies. The comparative analyses of different social practices and dynamics in similar political environments will help us understand the various courses Eastern-European countries took in overcoming their communist past and can serve as a basis for a follow-up research of the Transition process.'";1026120;1026120;ERC-2010-AdG_20100407;/ERC-AG;SOFIISKI UNIVERSITET SVETI KLIMENT OHRIDSKI;BG;"USTAV PRO SOUDOBE DEJINY AV CR V.V.I;Instytut Studiow Politycznych Polskiej Akademii Nauk;KOZEP-EUROPAI EGYETEM;EOTVOS LORAND TUDOMANYEGYETEM;LUDWIG BOLTZMANN GESELLSCHAFT GMBH;Zentrum für Zeithistorische Forschung Potsdam";"CZ;PL;HU;AT;DE";/SOC;1;0;0;1;0;0 104168;303172;B-reactable;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IOF;FP7;B-reactable: multimodal tabletop system for collaborative physiology monitoring and training;2013-02-22;2015-02-21;;Rapid development within the biomedical engineering field, especially Brain-Neural-Computer Interaction (BNCI) area, provides a solid technological base for new applications aimed at improving health and quality of life. In this project, aimed at combining research and training components, Dr. Valjamae will design, validate and optimize a novel multimodal system - B-Reactable - linking a tangible musical tabletop interface with BNCI technology for collaborative physiology monitoring and training in future health and professional applications. This interdisciplinary research project is based on the joint pilot work with Prof. Jorda, University of Pompeu Fabra, Barcelona in 2010-11. The project is designed to be a vehicle for the training and consolidation of the research outcomes for further exploitation in the EU. In the envisioned B-Reactable applications, users will explicitly or implicitly learn to monitor and control their physiological signals using tangible objects, and hence, understand and influence their cognitive or emotional states. The project will reinforce the international dimension of applicant’s scientific career by giving him the opportunity to be trained and acquire new knowledge in the Russian Federation, under direct guidance of Prof. Kropotov at the “Institute of Human Brain”, Russian Academy of Science (IHB-RAS) and Dr. Ossadtchi at St. Petersburg’s State University (SPSU). Prof. Kropotov is one of the leading neurofeedback scientists, with over 30 year research in computational models, normative databases, new paradigms and analysis methods, and extensive work on healthy adults, children and various patient groups. After training at IHB-RAS, Dr. Valjamae will bring his new experience and tangible outcomes to the renowned Swedish Institute for Disability Research at Linköping University, where together with Prof. Vastfjall he will test and further refine B-Reactable, targeting cognitive aging for improving users quality of life and wellbeing;188323,8;188323,8;FP7-PEOPLE-2011-IOF;/MC-IOF;LINKOPINGS UNIVERSITET;SE;;;/SCI;1;0;0;1;0;0 94958;255533;PLUREL;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IEF;FP7;Pluralism and Religious Freedom in Orthodox Countries in Europe;2010-09-01;2013-02-28;;A snapshot of European societies today reveals the importance of religious minority treatment and the grave potential that the latter can carry for instability and even social unrest in a situation of rapidly increasing religious diversity. Most conspicuous are the reactions of Muslim groups against what they perceive to be intolerant majorities, but other (less attended by the mass media) religious minority reactions are no less compelling in localities across Europe. A lack of spaces for worship (and especially of mosques), and other such limitations of religious freedoms form a fundamental aspect of religious minority experiences in Europe. Such limitations of religious freedoms are particularly prominent in Orthodox majority countries in Europe, where poor track records in terms of religious freedoms violations are evident in the disproportionately high number of religious freedoms convictions against Orthodox majority states in the European Court of Human Rights. What is the reason behind this state of affairs? Is there something intrinsic to Orthodoxy as a religious and social institution that makes it intolerant towards minorities? Or are there historical and political particularities in individual Orthodox majority countries that underlie the barriers to religious freedoms in each case? The proposed project seeks to understand and explain limitations of religious freedoms for minority faith groups in majority Orthodox countries in Europe. It will entail systematic, comparative, empirical and interdisciplinary research on the instances and nature of religious rights violations in Orthodox contexts, and on the factors and mechanisms influencing the latter. As such, in policy terms it will contribute to our understanding of the healthy balance point between the principle of subsidiarity, on the one hand and of pluralism, on the other. Further, this study of Orthodox context offers important insights for theories of secularisation and of multiple modernities.;202318,8;202318,8;FP7-PEOPLE-2009-IEF;/MC-IEF;Elliniko Idryma Evropaikis kai Exoterikis Politikis (HELLENIC FOUNDATION FOR EUROPEAN AND FOREIGN POLICY);EL;;;"/SCI;/EDU;/ITT";1;0;0;1;0;0 89733;224885;ALGGENOMES;ONG;FP7-PEOPLE;PEOPLE-2007-4-3.IRG;FP7;Algorithms for Analysis of Genes and Genomes;2009-01-15;2013-01-14;;In this project, we propose to develop new algorithms and probabilistic models for analysis of biological sequences (genomes and proteins encoded by them). We concentrate mainly on computer science aspects, striving to design efficient algorithms capable of processing large biological data sets currently available. In collaboration with molecular biologists, we will apply our techniques to several bioinformatics problems, such as finding location of genes in genomic sequences, evolution of duplicated regions of the genome, and study of mitochondrial genomes of yeast. Finding better solutions for these problems will lead to better genome annotations available as a basic resource for biological and medical researchers. In addition to the research objectives, we plan to establish lasting collaboration between the computer science researchers at the Faculty of Mathematics, Physics and Informatics and the life science researchers from the Faculty of Natural Science at Comenius University, Bratislava. We will involve faculty members and students from both faculties in common research projects, seminars and other activities. Dr. Tomas Vinar has experience with interdisciplinary bioinformatics research at leading universities in Canada and U.S.A. which makes him an ideal candidate for this effort.;100000;100000;FP7-PEOPLE-2007-4-3-IRG;/MC-IRG;UNIVERZITA KOMENSKEHO V BRATISLAVE;SK;;;"/SCI;/COO";1;0;0;1;0;0 93794;248778;ICT4DEPRESSION;CLO;FP7-ICT;ICT-2009.5.1;FP7;User-friendly ICT tools to enhance self-management and effective treatment of depression in the EU;2010-01-01;2013-04-30;;Major depression is currently the fourth disorder worldwide in terms of disease burden, and is expected to be the disorder with the highest disease burden in high-income countries by 2030. Estimated costs of depression are annually 177 and 147 million euro per 1 million inhabitants for major and minor depression respectively. Current treatment methods for depressive disorders can reduce the burden of this disease with about one third. The ICT4Depression consortium will develop an ICT-based system for use in primary care that will further improve patient outcomes and increase access to treatment. All technologies to be developed will be beyond state of the art and include 1) devices for monitoring activities and biosignals in a non-intrusive and continuous way, 2) treatments for depression and automatic assessment of the patient using mobile phone and web based communication, 3) computational methods for reasoning about the state of patients, progress of therapies, and the risk of relapse and 4) a flexible system architecture for monitoring and supporting people using continuous observations and feedback via mobile phone and the web. The ICT4Depression system is flexible and can easily be adapted for treatment of other mental diseases. The project will be carried out by an interdisciplinary consortium with 5 (research) organisations and 2 SME companies at the forefront of Artificial and Ambient Intelligence, wireless biosignal sensors, activity monitoring using cell phones, monitoring patient compliance with drug prescriptions, service oriented application for the health care domain, psychology, psychiatry, and internet-based psychological treatment. The project will boost European leadership in ICT-based treatment of mental illness and will provide ample opportunities for commercial exploitation.;3706506;2701845;FP7-ICT-2009-4;/CP;STICHTING VU;NL;"LINKOPINGS UNIVERSITET;INESC TEC - INSTITUTO DE ENGENHARIA DE SISTEMAS E COMPUTADORES, TECNOLOGIA E CIENCIA;UNIVERSITY OF LIMERICK;VERENIGING VOOR CHRISTELIJK HOGER ONDERWIJS WETENSCHAPPELIJK ONDERZOEK EN PATIENTENZORG;AARDEX GROUP SA;STICHTING GGZ INGEEST;PLUX - WIRELESS BIOSIGNALS S.A.;PLUX, ENGENHARIA DE BIOSENSORES LDA;STICHTING TRIMBOS- INSTITUUT, NETHERLANDS INSTITUTE OF MENTAL HEALTH AND ADDICTION";"SE;PT;IE;NL;CH";"/HCS;/ELM;/IPS;/MED";1;0;0;1;0;0 107211;333747;POLSPEC;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-CIG;FP7;Mechanisms controlling transcription of the plastid genome;2013-03-01;2019-05-18;;"Nucleus-encoded phage-type RNA polymerases are indispensable for the transcription of the mitochondrial and chloroplast genomes. They have fundamental roles in the biogenesis of the respiratory and photosynthetic compartments of plant cells. My previous research on mitochondrial transcription in the model plant Arabidopsis has led to the discovery of gene-specific transcriptional functions of the phage-type RNA polymerases RPOTm and RPOTmp in mitochondria and assigned individual roles to these enzymes in the biogenesis of the respiratory chain. RPOTmp is additionally found in plastids where its role and the role of a second phage-type enzyme, RPOTp, are largely unresolved. The proposed project aims to comprehensively define the functions of RPOTp and RPOTmp in plastids. It will employ i) a differential transcriptome sequencing (dRNA-seq) strategy and complementary molecular biology approaches to determine the gene specificities of these enzymes and generate a plastid genome-wide map of transcription start sites used by RPOTp or RPOTmp in plastids. ii) computational methods to identify potential cis-regulatory elements or parameters of plastid genes that direct the transcriptional activities of RPOTp and RPOTmp iii) in vitro transcription and interaction assays to validate the function of these elements and parameters in controlling transcription. The proposed research will generate fundamental knowledge on transcriptional processes in plants. It will clarify how plastid gene expression, and thus chloroplast biogenesis and photosynthesis, can be controlled via RPOTp and RPOTmp. My expertise in organellar transcription, the interdisciplinary strategy applied and new collaborations established during this project will contribute to excellent research outcomes and broaden research interests and competences of the host institute, which will strongly support me in obtaining a permanent senior position in research following my current junior professor appointment.";100000;100000;FP7-PEOPLE-2012-CIG;/MC-CIG;HUMBOLDT-UNIVERSITAET ZU BERLIN;DE;;;/LIF;1;0;0;1;0;0 107370;326496;CausalHighDim;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IEF;FP7;Causal Statistical Inference from High-Dimensional Data;2013-03-01;2015-02-28;;"'Statistical causal structure learning tackles the following problem: given iid observational data from a joint distribution, we estimate the underlying causal graph. This graph contains a directed arrow from each variable to its direct effects and is assumed to be acyclic. We propose to develop methods and mathematical theory for high-dimensional applications, where the number of variables is much larger than the number of samples. Independence-based methods like the PC algorithm can discover causal structures only up to Markov equivalence classes, that is some arrows remain undirected. And their consistency relies on strong faithfulness, which has been shown to be a restrictive condition. We propose to exploit structural equation models (SEMs) instead. They assume each variable to be a function of its direct causes and some noise variable. For certain restrictions (e.g. non-linear functions and additive noise) we obtain full identifiability; that is, given an observational distribution, we can recover the underlying causal graph, even without requiring faithfulness. On low-dimensional data sets, SEM-based methods already outperform competing methods like PC. However, they are not applicable to high-dimensional problems yet. One of the main goals of this research proposal is to develop new SEM-based methodology for high-dimensional applications and provide a theoretical analysis. In many applications, data are often collected under different environmental conditions. It is expected that the causal dependencies of a plant's genes, for example, behave differently under stress conditions like drought. Modeling these mechanism changes and exploiting them for causal structure learning is the second main goal of the research proposal. To the best of our knowledge, there is currently no methodology available for these tasks. We will apply the developed methodology to biological systems. The research is closely linked to the interdisciplinary project 'InfectX'.'";184709,4;184709,4;FP7-PEOPLE-2012-IEF;/MC-IEF;EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH;CH;;;/SCI;1;0;0;1;0;0 87576;209842;MATRIX;ONG;FP7-IDEAS-ERC;ERC-SG-PE6;FP7;Mixed-Matrix Interfaces for Enhanced Fine Chemicals Downstream Processing and Monitoring;2008-08-01;2014-07-31;;In the production of fine chemicals the downstream processing may amount up to 75 % of the total manufacturing costs, particularly when the product is aimed at nutritional or therapeutic use which demands a maximum purity. Current downstream processing strategies can face limitations whenever existing purification and separation processes are based on physico-chemical principles and thus exhibit a far more limited selectivity for the target compounds than is known from interactions involving biomolecules. The latter, on the other hand, are less robust and often require specific operating conditions (typically close to ambient) and feed compositions, which often restricts their broad application. This proposal presents an innovative, interdisciplinary approach on designing selective and tuneable interfaces for sensors and separations to be employed in downstream processing techniques. By combining recent advances in biology/biochemistry and chemistry and applying them to chemical engineering principles, the approach goes beyond concepts currently known, involving primarily engineered nucleic acids (aptamers) and tuneable ionic liquids (IL) incorporated in an appropriate support structure. The aim of this proposal is to make use of the unique properties of both biomolecules and ionic liquids in order to create supported mixed-matrix interfaces which exhibit properties that bulk materials can hardly achieve. Another novelty of this proposal is the aim to develop these interfaces in a modular way, namely by joining individually optimised elements during interface design in order to yield the desired overall properties. This approach warrants a maximum of degrees of freedom in the overall interface design while keeping the basic interface architecture constant, and thus overcomes one of the limitations that many conventional separation/purification techniques encounter during optimisation of the bulk material.;1498138;1498138;ERC-2007-StG;/ERC-SG;UNIVERSIDAD DEL PAIS VASCO/ EUSKAL HERRIKO UNIBERTSITATEA;ES;UNIVERSITAT ROVIRA I VIRGILI;ES;"/PSE;/IPS";1;0;0;1;0;0 87440;202809;CANCER SIGNALOSOMES;ONG;FP7-IDEAS-ERC;ERC-SG-LS1;FP7;Spatially and temporally regulated membrane complexes in cancer cell invasion and cytokinesis;2008-08-01;2013-07-31;;Cancer progression, characterized by uncontrolled proliferation and motility of cells, is a complex and deadly process. Integrins, a major cell surface adhesion receptor family, are transmembrane proteins known to regulate cell behaviour by transducing extracellular signals to cytoplasmic protein complexes. We and others have shown that recruitment of specific protein complexes by the cytoplasmic domains of integrins is important in tumorigenesis. Here our aim is to study three interrelated processes in cancer progression which involve integrin signalling, but which have not been elucidated earlier at all. 1) Integrins in cell division (cytokinesis). Since coordinated action of the cytoskeleton and membranes is needed both for cell division and motility, shared integrin functions can regulate both events. 2) Dynamic integrin signalosomes at the leading edge of invading cells. Spatially and temporally regulated, integrin-protein complexes at the front of infiltrating cells are likely to dictate the movement of cancer cells in tissues. 3) Transmembrane segments of integrins as scaffolds for integrin signalling. In addition to cytosolic proteins, integrins most likely interact with proteins within the membrane resulting into new signalling modalities. In this proposal we will use innovative, modern and even unconventional techniques (such as RNAi and live-cell arrays detecting integrin traffic, cell motility and multiplication, laser-microdissection, proteomics and bacterial-two-hybrid screens) to unravel these new integrin functions, for which we have preliminary evidence. Each project will give fundamentally novel mechanistic insight into the role of integrins in cancer. Moreover, these interdisciplinary new openings will increase our understanding in cancer progression in general and will open new possibilities for therapeutic intervention targeting both cancer proliferation and dissemination in the body.;1529369;1529369;ERC-2007-StG;/ERC-SG;TEKNOLOGIAN TUTKIMUSKESKUS VTT;FI;TURUN YLIOPISTO;FI;"/BIO;/LIF";1;0;0;1;0;0 104734;306784;EIGER;ONG;FP7-IDEAS-ERC;ERC-SG-PE9;FP7;Exploring the Inception of Galaxies and the Epoch of Reionization;2012-12-01;2016-11-30;;"Studying the nature of the first generation of galaxies to form in the Universe is central to efforts to understand the earliest phases of galaxy evolution and the physical processes driving cosmic reionization. Building on my recent success investigating galaxy evolution at redshifts z>6, I propose to recruit and lead the research team necessary to fully exploit my involvement in two Hubble Space Telescope (HST) imaging programmes focused on the high-redshift Universe. The first of these is a new, ultra-deep, proprietary imaging programme in the Hubble Ultra-Deep Field (on which I am co-PI) which will deliver the deepest near-IR image ever obtained and the first robust sample of z>9 galaxies. This dataset will produce the definitive measurement of the faint-end of the high-redshift galaxy luminosity function in the pre-JWST era, a key observational constraint necessary for understanding reionization. The second HST programme is the on-going, wide-area, CANDELS imaging survey, which will provide the first statistically significant sample of massive galaxies at redshifts 6;3707952;2898747;FP7-ICT-2011-8;/CP;THE UNIVERSITY OF BIRMINGHAM;UK;"UNIVERSITY OF SUNDERLAND;JACOBS UNIVERSITY BREMEN GGMBH;YDREAMS ROBOTICS SA;HERIOT-WATT UNIVERSITY;INESC ID - INSTITUTO DE ENGENHARIADE SISTEMAS E COMPUTADORES, INVESTIGACAO E DESENVOLVIMENTO EM LISBOA;GOETEBORGS UNIVERSITET;YDREAMS - INFORMATICA S.A.";"UK;DE;PT;SE";"/ICT;/EDU";1;0;0;1;0;0 107123;331962;G-ETI;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IOF;FP7;The Governance of Energy Technology Innovation: Investigating Regulatory Regimes in Shale Gas;2014-01-01;2015-12-31;;"Energy technology innovation (ETI) is widely considered crucial to both secure affordable energy supplies and cater climate goals. ETI does however not happen in vacuum. Rather, it is subject to a complex interplay between the public sector, private actors and the surrounding institutional environment. This research project focuses on the role of governance and regulation in fostering or preventing energy technology innovation. It assesses a recent technological break-through originating from the US with potentially significant repercussions for Europe: shale gas. Shale gas technology allows generating vital energy supplies domestically by at the same time replacing coal fired power plants, thus reducing carbon emissions. A nascent sector, shale gas provides a unique opportunity to explore the evolvement of regulatory regimes in a new industry; the way how actors and environments play out in different national contexts; and the opportunities and obstacles surrounding technology transfer from one regulatory regime to the other. The project contributes to the academic literature on regulatory governance, regimes and policy transfer. Adopting an interdisciplinary and mixed-method approach, it generates country level data on regulatory regimes in energy and provides for rich comparative insights into the cases of the US, Poland, Hungary and Bulgaria. Finally, it allows drawing policy relevant conclusions on the opportunities and limits of policy transfer in European energy regulation.";213959,5;213959,5;FP7-PEOPLE-2012-IOF;/MC-IOF;KOZEP-EUROPAI EGYETEM;HU;;;/LIF;1;0;0;1;0;0 106808;300879;MESMEC;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IEF;FP7;"""MEiobenthos in Shallow-water Marine ECosystems: A Monitoring, Experimental and Modelling Study to Understand Shallow-Water Meiobenthic Function in Marine Ecosystems and Assess its Economic Value""";2013-01-01;2014-12-31;;'The project MESMEC aims at assessing, understanding and predicting structure, diversity, function and importance of meiobenthos (small invertebrate sediment dwelling organisms) in shallow-water ecosystems in order to understand and predict better marine ecosystem dynamics and function in general. To achieve this we will perform 1) long-term monitoring analysis to understand natural spatial and temporal meiobenthic patterns and variability, 2) laboratory mesocosm experiments to assess impacts of environmental change (temperature, CO2, food) on meiofauna diversity and function, 3) the integration of these results into coupled ecosystem models to develop, consolidate and validate the meiobenthic component and assess current and predict future meiobenthic contribution to ecosystem function, 4) the quantification of the meiobenthic contribution to ecosystem goods and services and socio-economic value of coastal marine ecosystems, and 5) efficient engagement with scientific, policy and general end-users. The research training project, involving interdisciplinary experts, will provide a highly competent research fellow with the international experience and diversification and expansion of research and complementary skills needed to attain professional maturity and excellence in Marine Science in Europe. The project will deliver innovative marine ecosystem research and provide significant contributions to European Marine Management in light of the objectives of the European Union Marine Strategy Framework Directive.';209033,4;209033,4;FP7-PEOPLE-2011-IEF;/MC-IEF;PLYMOUTH MARINE LABORATORY;UK;;;/SCI;1;0;0;1;0;0 104636;316593;MONTENIGHT2012;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-NIGHT;FP7;Researchers’ Night in Montenegro 2012;2012-05-01;2012-11-30;;"'The Researchers Night in Montenegro 2012 project will continue the success story of the Nights 2009, 2010 and 2011, organized by the consortium, Ministry of Science, Natural History Museum of Montenegro, and the Montenegrin Science Promotion Foundation – PRONA in bridging the gap between the researchers and wider public. All events will take place on Friday, 28 September, from 12:00 – 24:00, with the central events (Hands-on-experiments, Science and Art installations, Gala opening, Movie projections, Presentation of interdisciplinary and inter-generational workshops (Culture, Geography, Physics and Chemistry of Food and Health) ‘Open science show’, Astronomical workshop, Science kindergarten, Concert) will take place in Podgorica – at three sites (Museums and Galleries, Art Pavilion, Karver) at Ribnica river bank while a series of smaller scale activities would happen in at three other towns in Montenegro (Botanical garden - Kolašin, Milk Diary - Nikšiæ and Institute of Marine Biology Kotor). Target groups of the projects are: high school students, university students, young people in general, preschool children, elementary school pupils, parents, school authorities and teachers, media and general public. It is planned to have at least 3500 of direct participants, and to cover at 40% of Montenegrin population or 250000 people with awareness campaign. At least 200 people, from which 50 researchers coming from different sectors and fields of research, will implement the Researchers’ Night’s activities. The main aim of 2012 project is to fulfill the goal of this EU - Marie Curie action that is to enhance the role of researchers in the mainstream of the society. Project Researchers’ Night is fun, educational and unique event that gathers general population and researchers from academic institutions, the business sector, various NGOs, governmental institutions, international agencies, including guests from around the region and young-talent programs.'";38111,61;35000;FP7-PEOPLE-2012-NIGHT;/CSA-SA;MINISTARSTVO NAUKE;ME;"J.U. PRIRODNJACKI MUZEJ CRNE GORE PODGORICA;""Fondacija za promovisanje nauke """"PRONA""""""";ME;/LIF;1;0;0;1;0;0 105029;316331;POLARIS;ONG;FP7-REGPOT;REGPOT-2012-2013-1;FP7;Unlocking the research potential of 3Bs Group, University of Minho, in Nanomedicine field to strengthen its competitive position at the European level;2012-10-01;2015-09-30;http://projectpolaris.eu/;3Bs is situated in one of the most industrialised regions of Northern Portugal (PT11) where the economy is strongly based on traditional, low-tech and small family businesses. Withstanding these traditions, the group has been a lighthouse and an example on the exploitation of the regional research potential within the biomedical area. Based on interdisciplinary research where collaboration and cooperation are hallmarks of its culture, 3Bs is worldly recognised for its excellence and innovative approaches in the field of macro and microscale processing of biomaterials. The project POLARIS aims to strengthen this position of 3Bs by boosting the group activity in the field of Nanomedicine. An action plan that involve upgrading the group infrastructure with state of the art equipments for processing and characterisation of biomaterials at nanoscale as well as recruiting experienced researchers and technical staff in this field has been created and will be attained by the close cooperation with 4 leading European institutions: Chalmers University of Technology, Max Planck Institute for Intelligent Systems, University College Dublin and University of Strathclyde Glasgow. Transfer of know-how and experience between the partners will be enhanced by several events targeting scientific community but also the general public. A local SME – StemMatters is also part of the partnership since the 3Bs aims to become dynamic “innovation engine”, facilitating and accelerating the transfer of innovative technology from basic research to industry. Thus, POLARIS seeks for actual implementation of the obtained results that can be a vital “bridge” to growth, competitiveness, sustainability and employment in PT11.;3128788,91;2811238;FP7-REGPOT-2012-2013-1;/CSA-SA;UNIVERSIDADE DO MINHO;PT;;;/SCI;1;0;0;1;0;0 104857;307360;XFLOW;ONG;FP7-IDEAS-ERC;ERC-SG-PE8;FP7;Ultrafast X-Ray Tomography of Turbulent Bubble Flows;2013-01-01;2016-12-31;;"Multiphase reactors are omnipresent in chemical engineering and dominate today's manufacturing of chemical products such that they are present in most of our daily products. That implies a huge economic and ecologic impact of the reactor performance. The basic idea of a multiphase reactor is to contact chemical precursors and catalysts in a sufficient time for the reaction to proceed, but reactor performance is crucially affected by the complex reactor hydrodynamics. A proper optimization would imply that multiphase flows are adequately understood. Gas bubbled into a pool of liquid is the simplest example of a multiphase reactor. Bubble columns or distillation columns, however, house millions of bubbles emerging in swarms with interactions such as coalescence and breakage events that determine the whole process behaviour. The understanding of such disperse gas-liquid flows is still fragmentary and requires a ground-breaking update. The aim of the project is to apply the worldwide fastest tomographic imaging method to study such turbulent gas-liquid dispersed flows in column reactors such as bubble columns and tray columns. The project intends to provide unique insights into the bubble swarm behaviour at operating conditions that have been hidden so far from the engineer's eyes. The project is foreseen to enhance the fundamental understanding of hydrodynamic parameters, evolving flow patterns and coherent structures as well as coalescence and breakage mechanisms, regardless of if the systems are pressurized, filled with particle packings, operated with organic liquid, slurries or with internals. The interdisciplinary team shall re-establish the process intensification route for multiphase reactors by a new understanding of small-scale phenomena, their mathematical description and extrapolation towards the reactor scale and therewith providing a tool for reactor optimization.";1172640;1172640;ERC-2012-StG_20111012;/ERC-SG;HELMHOLTZ-ZENTRUM DRESDEN-ROSSENDORF EV;DE;;;"/PSE;/EAR";1;0;0;1;0;0 106509;316432;QOCAN;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IRSES;FP7;Quantum optics of carbon nanostructures;2013-01-01;2016-12-31;;A scientific trend, which has emerged in recent years, is to combine the methods of quantum optics with the advances in design and preparation of various nanostructures. This innovative field of physics, arising from the achievements of modern nanotechnology, offers the possibility of both the fundamental study of light-matter interaction in unusual artificial quantum systems and the development of optoelectronic nanodevices with unique characteristics. The proposed theoretical research lies within this interdisciplinary trend and joins two different important fields of the modern physics: the first one is devoted to the quantum optics, the second deals with the carbon-based nanostructures – carbon nanotubes and graphene. The main goal of the research is to combine the efforts of four scientific teams from Britain, Iceland, Russia and Brazil in achieving the following objectives: to develop fundamentals of the interaction between carbon nanostructures and quantum light, to reveal and analyse various quantum-electrodynamics effects in carbon nanostructures, and to create a theoretical basis for using carbon nanostructures as elements of novel optoelectronic nanodevices.;96000;96000;FP7-PEOPLE-2012-IRSES;/MC-IRSES;THE UNIVERSITY OF EXETER;UK;HASKOLI ISLANDS;IS;/SCI;1;0;0;1;0;0 104937;307311;InteGraDe;ONG;FP7-IDEAS-ERC;ERC-SG-PE7;FP7;Integrating Graphene Devices;2012-09-01;2017-08-31;;Technology requirements for future IC systems include low power computing and communication, sensing capabilities and energy harvesting. These will unlikely be met with silicon technology alone. The proposed research therefore investigates graphene as a potential alternative technology and contributes to bridging the “valley of death” in innovation that is all too present in Europe. In detail, the proposal focuses on the experimental exploration of novel (opto-) electronic devices and systems based on graphene. Strong emphasis is put on integration, defined as an interdisciplinary approach combining graphene manufacturing, graphene process technology, device engineering and -physics as well as system design. This kind of approach is urgently needed in order to open new horizons for graphene, because it enables a transition from fascinating science to a realistic demonstration of graphene’s application potential in electronics and optoelectronics. The first requirement for the applicability of graphene in ICT is a scalable graphene fabrication technology that can be co-integrated with silicon. The second logical aspect to be investigated is the intricate relationship between process technology and graphene device performance. The third aspect to be considered when discussing integration is how devices can be integrated in existing or future systems, including questions of circuit design. Will graphene systems outperform existing solutions and thus replace them? Will new functionalities emerge and generate novel applications? Hence, the key objectives of this proposal are: 1) a scalable, CMOS compatible large area fabrication technology for graphene and graphene devices, 2) demonstration and assessment of performance advantages and new functionalities of RF graphene devices, 3) high performance graphene-based optoelectronic devices integrated with silicon technology and 4) experimental exploration of the performance potential of graphene-based integrated systems.;1498687;1498687;ERC-2012-StG_20111012;/ERC-SG;UNIVERSITAET SIEGEN;DE;KUNGLIGA TEKNISKA HOEGSKOLAN;SE;"/PSE;/AER;/SPA";1;0;0;1;0;0 87472;207441;DEDOM;ONG;FP7-IDEAS-ERC;ERC-SG-PE4;FP7;Development of Density Functional Theory methods for Organic Metal Interaction;2008-07-01;2013-12-31;;"First principles Density-Functional Theory (DFT) methods have been widely applied for computing electronic and optical properties of different systems. Recently theoretical modeling of metal-organic interfaces received a much attention due to their importance in different nanoscience fields. However, common (i.e. local and semi-local) approximations to the exchange-correlation (XC) functional of DFT show several shortcomings in describing metal-organic energy-levels alignment and thus charge-transfer. Aim of the DEDOM (DEvelopment of Density functional theory methods for Organic Metal interaction) project is to elaborate new theoretical methods beyond the current state-of-the-art for the description of the electronic and optical properties of organic molecules linked or deposited on metal surfaces or metal nanoparticles. This task includes: i) the development of new and efficient XC functionals, based on optimized effective potential (OEP) and including exact-exchange and correlation from many-body theory, to obtain an accurate description of charge-transfer between organic molecules and metal surfaces; ii) the investigation of optical properties, including light-emission, of organic molecules on metal surfaces using Time-Dependent DFT; iii) the description of metals using Green’s functions and multi-scale approaches to investigate metal-induced modification of the optical properties of organic molecules, including fluorescence quenching or enhancement due to the coupling of electronic excitations to plasmons. The DEDOM project is theoretically and technically extremely challenging due to the use of unconventional orbital-dependent XC-functionals and it requires a strong interdisciplinary effort, joining solid-state physics, theoretical chemistry, electromagnetic engineering and implementation of advanced computational techniques. If successful, it will represent a major progress in the theoretical description of organic-metal interfaces.";1250000;1250000;ERC-2007-StG;/ERC-SG;CONSIGLIO NAZIONALE DELLE RICERCHE;IT;;;"/PSE;/MAT";1;0;0;1;0;0 191151;609883;MERIC;ONG;FP7-IDEAS-ERC;ERC-2013-SyG;FP7;Mechanisms of Evasive Resistance in Cancer;2014-05-01;2020-04-30;;"Cancer is a major health problem due to the failure of current therapies to effectively eradicate the disease. Alternative signaling pathways compensate for a therapeutically targeted pathway, a process referred to as 'evasive resistance'. The identities of the alternative signaling pathways and functional interconnections that underlie evasive resistance remain widely unknown. We propose to integrate cutting-edge clinical, molecular, and computational sciences to understand the signaling defects that allow tumors to evade therapy. With its synergistic, interdisciplinary approach, the proposed project is, to our knowledge, unique in Europe and possibly worldwide. Within the framework of rigorously designed clinical studies, a clinician will provide basic research scientists with diseased tissue isolated before therapy, during treatment or at the time of tumor progression. The tissue, chosen based on medical importance, accessibility to repeated sampling, and ethical considerations, will be from hepatocellular carcinoma. Tumor tissue will be obtained by needle biopsy and snap frozen to preserve in vivo properties. The basic research scientists and a computational biologist will determine, characterize and model the underlying signaling defects. Importantly, using longitudinal clinical samples in combination with mouse and cellular HCC model systems, we will seek to define treatment-related changes in cell signaling that allow tumors to circumvent therapy. This process will be iterative such that changes in treatment strategies will again be monitored in the same patient or experimental model. Insights gained will be used (i) to understand mechanisms of evasive resistance, (ii) to identify novel drug targets and predictive biomarkers, and (iii) to rationally design personalized medicine that ultimately increases therapeutic effectiveness and reduces financial burden. This innovative, comprehensive endeavor will improve diagnosis, treatment and clinical outcome.";11197882;11197882;ERC-2013-SyG;/ERC-SyG;UNIVERSITAT BASEL;CH;"EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH;UNIVERSITATSSPITAL BASEL";CH;/SCI;1;0;0;1;0;0 90756;221701;CARBOTRONICS;ONG;FP7-PEOPLE;PEOPLE-2007-2-1.IEF;FP7;Opto-electronic properties of graphene and other carbon nanostructures;2008-09-01;2010-08-31;;"Project covers theortical/computational studies of optoelectronic properties of graphene and other carbon-based nanostructures, aimed at both fundamental effects and application in future graphene nanotechnology. Major goals are: (i) learning new, powerful methods of electronic-structure calculations (quantum Monte Carlo and density functional theory) and their application for graphene nanostructures; (ii) learning methods of field theory and combining them with extensive present expertise for the studies of many-body effects in electronic and optical response, with expected application in novel nanodevices; (iii) learning complementary skills for establishment of home interdisciplinary research group focused on nanoscience/nanotechnology of new structures/materials and integrated with big EU research programmes (leadership skills, acquiring funds, project management, work in collaboration); (iv) acquintance with (and import of) teaching methods/practices (excellence in this academic skill being crucial for Applicant’s promotion to a full professor upon return). Project’s success relies on Applicant’s present potential/experience (mostly in fundamental research, but also in teaching and leadership) and on superb quality of the host (Cambridge in general, Cavendish Laboratory in particular) in all essential aspects (research, participation in European science, and teaching). The main results will be: (i) multi-aspectual individual education of the Applicant (at a rate possible only due to continuous interaction with Europe’s best specialists and exposure to unparalleled academic environment) as well as (ii) enhancement of attractiveness and potential of European science by means of transfer of knowledge and research/academic habits from the leading European university to a major but still rapidly developing research/academic institution in Poland and (iii) efficient incorporation of the latter in priority EU research programmes.";234536,33;234536,33;FP7-PEOPLE-2007-2-1-IEF;/MC-IEF;THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE;UK;;;"/SCI;/EDU";1;0;0;1;0;0 95608;247486;MANEQUI;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IRSES;FP7;Mathematical studies on critical non-equilibrium phenomena via mean field theories and theories of nonlinear partial differential equations;2010-04-15;2014-04-14;;The aim of the present project is to unite, in a cooperative and synergetic way, the work of researchers from 5 European institutions, 2 in Italy (Naples Federico II and Naples Second University) and 3 in Greece (FORTH Heraklion, University of Crete and University of the Aegean), in order to consolidate and definitely establish scientific collaborations with a Third Country (Japan). The focus of the research project will be in mathematical analysis, particularly nonlinear elliptic and parabolic partial differential equations, including applications to problems of particular relevance in various fields in Physics, Biology and Medical Sciences, such as material sciences, chemotaxis, tumour growth, all finalized towards results of international relevance. The marked interdisciplinary features of the proposed researches are expected to greatly benefit of the complementary backgrounds and fields of interests of the participants. This project is motivated by an already existing collaboration between some European members of the project with first class scientist Professor T. Suzuki of Osaka University, as well as with other Japanese mathematicians. We emphasize that the availability of direct interaction among the European institutions and the Third Country has already been partly implemented by Professor Suzuki’s visiting and lecturing at Naples Federico II University (2007 and 2008) and in Greece (2007) as well as by numerous stages of Italian and Greek participants at Japanese institutions. The collaboration in Japan will mainly take place at Osaka University, where Professor Suzuki will coordinate the activities and supervise the training programme of the European early stage researchers, and at 3 other Japanese universities. The present requested financial support would allow to maintain, reinforce and extend the already existing collaboration, as well as to provide an invaluable training of young European mathematicians at prestigious Japanese research centres.;176400;176400;FP7-PEOPLE-2009-IRSES;/MC-IRSES;UNIVERSITA DEGLI STUDI DI NAPOLI FEDERICO II.;IT;"FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS;PANEPISTIMIO KRITIS;UNIVERSITA DEGLI STUDI DELLA CAMPANIA LUIGI VANVITELLI;PANEPISTIMIO AIGAIOU";"EL;IT";"/SCI;/EDU;/ITT";1;0;0;1;0;0 191292;609989;4D-GENOME;ONG;FP7-IDEAS-ERC;ERC-2013-SyG;FP7;Dynamics of human genome architecture in stable and transient gene expression changes;2014-06-01;2019-05-31;;The classical view of genomes as linear sequences has been replaced by a vision of nuclear organization that is both dynamic and complex, with chromosomes and genes non-randomly positioned in the nucleus. Process compartmentalization and spatial location of genes modulate the transcriptional output of the genomes. However, how the interplay between genome structure and gene regulation is established and maintained is still unclear. The aim of this project is to explore whether the genome 3D structure acts as an information source for modulating transcription in response to external stimuli. With a genuine interdisciplinary team effort, we will study the conformation of the genome at various integrated levels, from the nucleosome fiber to the distribution of chromosomes territories in the nuclear space. We will generate high-resolution 3D models of the spatial organization of the genomes of distinct eukaryotic cell types in interphase to identify differences in the chromatin landscape. We will follow the time course of structural changes in response to cues that affect gene expression either permanently or transiently. We will analyze the changes in genome structure during the stable trans-differentiation of immortalized B cells to macrophages and during the transient hormonal responses of differentiated cells. We plan to establish novel functional strategies, based on targeted and high-throughput reporter assays, to assess the relevance of the spatial environment on gene regulation. Using sophisticated modeling and computational approaches, we will combine high-resolution data from chromosome interactions, super-resolution images and omics information. Our long-term plan is to implement a 3D browser for the comprehensive mapping of chromatin properties and genomic features, to better understand how external signals are integrated at the genomic, epigenetic and structural level to orchestrate changes in gene expression that are cell specific and dynamic.;12272645;12272645;ERC-2013-SyG;/ERC-SyG;FUNDACIO CENTRE DE REGULACIO GENOMICA;ES;FUNDACIO PARC CIENTIFIC DE BARCELONA;ES;/SCI;1;0;0;1;0;0 107044;318960;GENDERCIT;ONG;FP7-PEOPLE;FP7-PEOPLE-2012-IRSES;FP7;Gender and Citizenship;2013-02-01;2017-01-31;;"The overall aim of the proposal is to implement an exchange program and to promote a mutual and beneficial transfer of knowledge between Europe (Spain, Portugal, Italy and France) and Latin America (Argentina and Mexico) in the field of Gender Studies, in order to enrich the theoretical framework, to consolidate the institutional dimension of the different research programs having gender as focus and to set up new research activities. The proposal focuses issues of gender and citizenship, which are crucial both for the advancement of gender theories and of gender policies. Specific objectives of the proposal are in fact: a) The opening of interdisciplinary, original and innovative research perspectives; b) The contribution to the assessment and the definition of gender policies at international, national and local level in the two continents; c) the establishment of a network that will allow the reciprocal transfer of knowledge between Europe and Latin America The three objectives are extremely relevant, both for the ERA –the European Research Area-, considering that the field of Gender Studies is still underdeveloped in comparison with the United States, and for the EU policy that has put gender equality as a main goal to reach. The exchange program will allow senior and junior researchers to take part in PhD courses, Master programs, Intensive programs, Summer Schools; will encourage co-direction of PhD and will produce publication of books and articles in peer reviewed journals. Outreach activities are foreseen outside the academic world reaching politicians, stakeholders and the general public with the aim of suggesting strategies and proposing recommendations for promoting gender equality.";606900;606900;FP7-PEOPLE-2012-IRSES;/MC-IRSES;UNIVERSIDAD PABLO DE OLAVIDE;ES;"UNIVERSITE PARIS 8 VINCENNES SAINT-DENIS;UNIVERSITA DEGLI STUDI DI FIRENZE;UNIVERSIDAD DE GRANADA;INSTITUTO DE CIENCIAS SOCIAIS;ASOCIACION CENTRO UNESCO DE CEUTA";"FR;IT;ES;PT";/SCI;1;0;0;1;0;0 90869;219266;MATINEE;ONG;FP7-PEOPLE;PEOPLE-2007-4-2.IIF;FP7;Mathematical Interfaces for Epidemiology and Environment;2009-08-20;2010-10-19;;This proposal would bring a mathematical epidemiologist from the U.S. to the University of Lyon (France) to collaborate with researchers in the Biometry and Evolutionary Biology Laboratory in research on the nosocomial transmission of rotavirus in pediatric and other hospital wards. Because of inadequate sterilization and pathogen resistance to antibiotics, healthcare workers and hospital equipment act as vectors to spread these infections from one patient to another, causing thousands of deaths each year, especially among children under five years of age. This project proposes to develop and analyze a sequence of mathematical models describing the transmission dynamics, beginning with deterministic compartmental models which describe the average spread of infections at the hospital level and progressing to stochastic and network-based models which take into account individual variations in transmission within small populations such as wards, and the structure of infectious contacts that connects multiple wards through workers and equipment moving from one ward to another. The project also includes two methodological components: one which will compare epidemiological indices of infection transmission such as the basic reproductive number, to see which best capture the effects of contact structures (how potential infection events occur), and another which applies uncertainty and sensitivity analyses in order to derive a measure of confidence in the results. This interdisciplinary collaboration, broad both in the fields of expertise from which it draws and in the spectrum of modeling approaches it uses, aims to play an important role in the context of public health: by putting predictive tools at the disposal of the community of physicians, it aligns with the public health strategy of the European Community in improving the capability to respond to significant public health threats.;225566,68;225566,68;FP7-PEOPLE-2007-4-2-IIF;/MC-IIF;UNIVERSITE LYON 1 CLAUDE BERNARD;FR;;;"/SCI;/COO";1;0;0;1;0;0 92179;235012;EUROISOTOPES;ONG;FP7-PEOPLE;FP7-PEOPLE-IEF-2008;FP7;Tracing the History of Isotope Sciences in Europe: Circulation and Uses of Radiocarbon, 1945-1965;2009-09-14;2011-09-13;;First discovered and manufactured in Berkeley Radiation Laboratory in 1940, the isotope carbon-14 (C-14, also called radiocarbon) has since played a fundamental role in the development of biomedical sciences, human sciences and environmental sciences. This project aims to produce an up-to-date history of its first applications in Europe, by exploring the circulation of materials, instruments and techniques based on this isotope after World War 2. In particular, research will focus on three case studies of appropriation of isotopic tracing techniques, which will be approached from a transnational perspective: the use of C-14 techniques by molecular biologists, the use of radiocarbon in archeological dating and the use of carbon-14 in environmental sciences. The study of the use of similar techniques in different disciplines will allow for an analysis on interdisciplinary connections between fields, and also for a comparative study of the transfer and validation of these techniques among different research communities. Besides studying these methodological and epistemological questions, the project will result in a up-to-date chronology and a guide of sources on the history of nuclear sciences in Europe, as well as a repository of oral interviews to key actors in thsi field. The project will also pay attention to the public image of these researches in the public sphere, in relation to the campaign “Atoms for Peace” and the development of nuclear industry in Europe. In doing so, the project will develop new historiographical techniques related to the use of the press as a source in the history of science.;227984,41;227984,41;FP7-PEOPLE-IEF-2008;/MC-IEF;UNIVERSITE DE STRASBOURG;FR;;;"/SCI;/EMP";1;0;0;1;0;0 88346;220287;EURO_CITI;ONG;FP7-PEOPLE;PEOPLE-2007-2-1.IEF;FP7;EUROpean CITIzenship practice: political participation of transnational European senior migrants;2008-07-01;2010-06-30;;In the context of European integration and the emergence of a leisure-oriented culture, traditional lifestyles have been replaced by new patterns of behaviour. In this regard, a remarkable phenomenon is the increasing migration of mainly retired Europeans to the coastal regions of the Mediterranean. In the last decade, major changes concerning the social and political participation of such amenity-seeking migrants have been taking place, chiefly triggered by granting EU-foreigners active and passive voting rights in local elections. Given the fact that many of the retired residents belong to the economic elite and were successful professionals, they count on powerful tools, know-how and resources to integrate and take leadership in local politics. Migrants from northern Europe founded their own parties e.g. in many Spanish municipalities and are currently active in the local councils. EURO_CITI is an innovative and interdisciplinary research project dealing with the different forms of political participation of retired European residents and principally aimed at discussing the practice of European Citizenship both in a conceptual and empirical framework.;151369,07;151369,07;FP7-PEOPLE-2007-2-1-IEF;/MC-IEF;AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS;ES;;;"/SCI;/EDU";1;0;0;1;0;0 90207;233358;NEURONAGE;ONG;FP7-IDEAS-ERC;ERC-AG-ID1;FP7;Molecular Basis of Neuronal Ageing;2009-05-01;2015-04-30;;Ageing is associated with marked decrease of neuronal function and increased susceptibility to neurodegeneration, in organisms as diverse as the lowly worm Caenorhabditis elegans and humans. Although, age-related deterioration of the nervous system is a universal phenomenon, its cellular and molecular underpinnings remain obscure. What mechanisms are responsible for the detrimental effects of ageing on neuronal function? The aim of the proposed research programme is to address this fundamental problem. We will implement an interdisciplinary approach, combining the power of C. elegans, a highly malleable genetic model which offers a precisely defined nervous system, with state-of-the-art microfluidics and optical imaging technologies, to manipulate and monitor neuronal activity during ageing, in vivo. Our objectives are four-fold. First, develop a microfluidics platform for high-throughput manipulation and imaging of specific neurons in individual animals, in vivo. Second, use the platform to monitor neuronal function during ageing in isogenic populations of wild type animals, long-lived mutants and animals under caloric restriction, a condition known to extend lifespan from yeast to primates. Third, examine how ageing modulates susceptibility to neuronal damage in nematode models of human neurodegenerative disorders. Fourth, conduct both forward and reverse genetic screens for modifiers of resistance to ageing-inflicted neuronal function decline. We will seek to identify and thoroughly characterize genes and molecular pathways involved in neuron deterioration during ageing. Ultimately, we will investigate the functional conservation of key isolated factors in more complex ageing models such as Drosophila and the mouse. Together, these studies will lead to an unprecedented understanding of age-related breakdown of neuronal function and will provide critical insights with broad relevance to human health and quality of life.;2376000;2376000;ERC-2008-AdG;/ERC-AG;FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS;EL;;;/SCI;1;0;0;1;0;0 90579;231019;NANO-MAT;ONG;FP7-PEOPLE;PEOPLE-2007-4-3.IRG;FP7;Self-Assembled Nanostructures for Organic-Inorganic Hybrid Nanomaterials;2009-02-01;2013-01-31;;Bio-inspired self-assembled nanostructures comprises one of the most exciting developments in the fields of chemistry, physics, biology and materials science. These materials are vastly ordered structures with high-aspect ratio and are used as scaffolds to create chemically functionalized surfaces with control at the atomic level. The chemical properties of the materials are highly tailorable based on the choice of organic struts. These remarkable characteristics and properties have interesting applications such as photovoltaic cells, selective catalysis, adsorption, sensing, and bio-recognition. Herein, it is now proposed to extend the range of properties of self-assembled nanomaterials to encompass presentation of chemically functional groups on novel nanostructures. Our design approach relies upon hydrogen bonding, amphiphilic and metal chelating small molecules programmed to form nanostructures upon need. The work to be performed will encompass design, synthesis and characterization of self-assembled nanoscale materials in variuos architectures. Quantitative experimental studies of metal binding capability and systematic experimental use of the nanostructures will be studied for building devices for practical applications. The proposed interdisciplinary studies will accumulate knowledge that may lead to novel highly selective catalytic ensembles, chemical sensors, chemically smart coatings and alternative renewable energy products.;100000;100000;FP7-PEOPLE-IRG-2008;/MC-IRG;Bilkent Üniversitesi;TR;;;"/SCI;/COO";1;0;0;1;0;0 88608;223037;INTERLINKS;ONG;FP7-HEALTH;HEALTH-2007-3.2-2;FP7;Health systems and long-term care for older people in Europe – Modelling the INTERfaces and LINKS between prevention, rehabilitation, quality of services and informal care;2008-11-01;2011-12-31;;The objective of this 3-year project is to construct and validate a general model to describe and analyse long-term care (LTC) systems for older people from a European perspective. The particular aspects of the different emerging national models that currently address long-term care needs in Europe will be used to show how the links to health care services, the quality of LTC services, the incentives for prevention and rehabilitation, and the support for informal carers can be governed and financed to enhance structures, processes and outcomes of LTC systems. Based on the assumption that LTC systems in Europe have only started to develop at the boundaries of health and social care, the project will focus on the elaboration of concepts, indicators and models for policies and practice at the interfaces and links between health systems and LTC. Good practice determinants will be identified and validated across countries. A European ‘state of the art’ model for describing and analysing long-term care provision will thus be constructed as an analytical toolbox that takes into account pathways of reform policies at any stage of a national LTC system’s development. The project outcome will guide policy analysis and design, permit comparison and will substantially broaden the scientific base that supports the Member States to better organise their health and LTC systems. It will also integrate the professional and the non-professional domain with inputs from a wide range of stakeholders by means of National Expert Panels and European-level Sounding Board Conferences. The project will be carried out by a consortium of 17 partners from universities, national and international research institutes with international and interdisciplinary expertise, also in cross-national research. The consortium represents 14 Member States covering different welfare regimes and geographical domains to allow for the regional and developmental, path-dependent differences to be addressed.;3894297,2;2985919;FP7-HEALTH-2007-B;/CP-FP;EUROPAISCHES ZENTRUM FUR WOHLFAHRTSPOLITIK UND SOZIALFORSCHUNG;AT;"CMT PROOPTIKI CONSULTING MANAGEMENT TRAINING;WISSENSCHAFTSZENTRUM BERLIN FUR SOZIALFORSCHUNG GGMBH;STICHTING VILANS;STUDIO COME SRL;THE UNIVERSITY OF BIRMINGHAM;UNIVERSITAT DE VALENCIA;INSTITUT PRE VYSKUM PRACE A RODINY;INSTITUT FUER SOZIALE INFRASTRUKTUR GBR;INSTITUT DE RECHERCHE ET DOCUMENTATION EN ECONOMIE DE LA SANTE ASSOCIOATION;TERVEYDEN JA HYVINVOINNIN LAITOS;INSTITUT ZA VAROVANJE ZDRAVJA REPUBLIKE SLOVENIJE;SYDDANSK UNIVERSITET;UNIVERSITY OF KENT;HAUTE ECOLE SPECIALISEE DE SUISSE OCCIDENTALE;STOCKHOLMS LANS LANDSTING";"EL;DE;NL;IT;UK;ES;SK;FR;FI;SI;DK;CH;SE";"/SOC;/MED";1;0;0;1;0;0 103608;300077;RAPIDEVO;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IOF;FP7;Rapid evolutionary responses to climate change in natural populations: Integrating molecular genetics, climate predictions and demography into an eco-evolutionary modelling framework;2013-01-01;2015-12-31;;"Intensification and increased frequency of weather extremes is emerging as one of the most dramatic aspects of climate change. Thus, the study of ecological implications of global-scale changes is expanding from a focus on trends (e.g., mean temperatures) to broader investigations including the effects of extreme events and associated catastrophic disturbances (e.g., floods, fires, droughts). However, investigations exploring adaptations of individuals and species to altered patterns of extreme events are still rare and overarching studies are greatly needed. Crucially, rapid evolutionary and adaptative processes are highly relevant for understanding and predicting species responses to climate change. I propose to investigate the selective consequences of periodic catastrophic disturbances on genetic diversity and life-history traits, using marble trout (Salmo marmoratus) populations living in Slovenian streams as a model system. In this system, flash floods and debris flows causing massive fish mortalities are increasing in frequency and intensity. I will use an innovative multidisciplinary and interdisciplinary approach, combining (i) molecular genetics, (ii) demographic analysis and statistical characterization of temporal and spatial patterns of flood events, and (iii) life-history, demographic and eco-evolutionary modelling, to understand and predict the selective consequences of the altered pattern of catastrophic disturbances on the genetic composition and life-history traits of marble trout. Bringing together genetic, climatic, life-history and demographic aspects in this model system will allow the development of an overarching and general modelling and conservation framework for rapid evolutionary and adaptive processes, and will establish a reference of how to explore the consequences of climate change-induced intensification of weather extremes on natural populations.";264639,6;264639,6;FP7-PEOPLE-2011-IOF;/MC-IOF;POLITECNICO DI MILANO;IT;;;/SCI;1;0;0;1;0;0 97685;254835;WASTE PREVENTION;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IIF;FP7;Analysis of Waste Prevention Behaviour through a Conceptual Statistical Model and Scenario Simulation;2011-01-27;2013-01-26;;"The justification for this proposal is based on the growing awareness that environmental problems have more to do with the decisions of ordinary people as opposed to governments and corporations. This proposal argues that the solution for solid waste issues involves not only technical or economic regulations or both, but also real changes in individuals’ behaviour. Hence, with the aim to provide an explanation to such complex interaction of questions, an interdisciplinary study is required. The main objective is to develop a better critical understanding of impact of influential factors on individuals’ waste prevention behaviour (WPB). The specific objectives are: (a) to verify the conceptual model for WPB by carrying out a survey in two different local conditions; (b) to improve the conceptual model by including the influence of situational factors and specific social norms regarding waste prevention (WP); (c) to investigate the results of the WPB survey through structural equation modelling analysis, and; (d) to understand policy interventions on WP using the behaviour model with an agent-based simulation and, to then establish possible future solid waste reduction scenarios. Thus, the methodology will test a pre-conceived behaviour model for WP by including specific social norms and situational factors as behaviour predictors. A simulation will be designed to test out possible policy interventions based on a virtual society of autonomous agents. This bottom-up approach, where a complex system is viewed as a large set of small interacting components, will identify individuals’ behaviours and their interactions. The results may provide the much-need justification to make the municipal authorities in developed and developing cities apply WP policies as their most important input to reduce solid waste generation.";173240,8;173240,8;FP7-PEOPLE-2009-IIF;/MC-IIF;THE UNIVERSITY OF SHEFFIELD;UK;;;"/SCI;/EDU;/ITT";1;0;0;1;0;0 94755;252263;LHC-PHYS;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IIF;FP7;Probing electrically charged Higgs bosons at the CERN's Large Hadron Collider: a collaboration between theory and experiment;2010-09-01;2012-08-31;;This collaborative project is in the area of high-energy particle physics phenomenology with the focus on electrically charged Higgs bosons. The proposal is a research programme where the applicant's expertise on various aspects of charged Higgs boson phenomenology in hadronic collisions is well-matched with that available at the host institution. The NExT institute has several leading world experts on the phenomenology of the Standard Model (SM) at present and future high-energy colliders both at the theoretical and experimental level (with groups working on the CMS and ATLAS collaborations at the CERN's LHC facility, where the aforementioned studies will take place). Moreover, NExT's mission is to promote fundamental research where theorists and experimentalists work together in the process of New Physics discovery, and the applicant is the ideal catalyst for this since his theoretical work has influenced experimental collaborations in the past. Hence this project will produce forefront research, mutually advantageous to both parties, based on a new raw model of a researcher with interdisciplinary skills. We are especially interested in the search for electrically charged Higgs bosons. Such particles are a necessity in numerous extensions of the SM which address its empirical and theoretical shortcomings. It is widely believed by contemporary particle physicists that the elusive Higgs bosons (both electrically neutral and charged) are potentially the key to answer the fundamental question of why elementary particles have mass. Their search is therefore the primary goal of the LHC. Overall, our aim is to contribute to a better understanding of the world of particle physics by performing, developing, and optimising both Monte Carlo and real data analyses to confirm or constrain such particles experimentally. This application is ideally timed, as the data-taking phase of the experiments at the LHC is due to start in 2010.;240289,6;240289,6;FP7-PEOPLE-2009-IIF;/MC-IIF;UNIVERSITY OF SOUTHAMPTON;UK;;;"/SCI;/EDU;/ITT";1;0;0;1;0;0 88243;201853;DIGIDEAS;ONG;FP7-IDEAS-ERC;ERC-SG-SH2;FP7;Social and ethical aspects of digital identities. Towards a value sensitive identity management;2008-10-01;2014-05-31;;Digital identity management concerns the control of digitized information pertaining to a person. This type of information is usually referred to as `personal data’, or ‘personally identifiable information’. With digitisation and automation processes pervading virtually all aspects and domains of society, the routine registration of personal identifiable data is increasing exponentially. The implied risks and challenges to fundamental rights like privacy and non-discrimination are recognized on the highest policy levels, but as of today still poorly understood or analyzed. In view of the fact that ‘identity’ is also a key concept in contemporary social theory, and conceptualisations of the relation between technology and society, ethics and normativity, a field of enquiry emerges at the crossroads of contemporary theoretical, technological and societal developments representing opportunities for frontier research. The overall aims of the project are to increase understanding of the social and ethical aspects of digital identity management (IDM), to further theorising the concept of identity, and to contribute to the quality and social/ethical acceptability of technological developments. The project will achieve these goals by bringing recent insights gained from several disciplines (science and technology studies, surveillance studies, social and technology philosophy, computer ethics) to bear on actual developments in digital identity management, thus exploring novel ways to identify and articulate the issues concerned. With a series of interdisciplinary studies focussing on different application areas of IDM, we intend to produce more fine-grained knowledge of the ways IDM is implicated in contemporary transformations of identity. The programme will involve three complementary PhD projects, and one integrative postdoc project, thus achieving a strong concentration of groundbreaking knowledge on a set of fast emerging intellectual and societal problems.;1833000;1833000;ERC-2007-StG;/ERC-SG;STICHTING ZUYD HOGESCHOOL;NL;;;/SOC;1;0;0;1;0;0 92272;237646;DNP4NANOCARAC;ONG;FP7-PEOPLE;FP7-PEOPLE-IEF-2008;FP7;Dynamic nuclear polarization - enhanced high resolution solid-state NMR spectroscopy for atomic 3D structure determination of functionalized nanotubes and other nano-sized objects;2009-04-01;2011-03-31;;"This project aims at developing the instrumentation and methodology required to perform solid-state sub-nanometer scale structural studies by Nuclear Magnetic Resonance (NMR). In the last decades NMR has proven to be a priceless tool to probe structure and dynamics of systems as diverse as glasses, metal surfaces, polymers and proteins, etc. However, the low sensitivity of the technique currently limits its outreach in material science, chemistry and biology. In order to overcome this limitation, we plan to use a technique called Dynamic Nuclear polarization (DNP) which is able to hyperpolarize nuclear spins. The DNP phenomenon, discovered at low magnetic fields (< 0.3 T), is far from being new but its usage at high magnetic fields (5 to 20 T and more) constitutes an exciting ongoing challenge. Compared to traditional NMR where the signal originates from thermal polarization, DNP enables us to enhance the NMR signal to noise by 1 to 4 orders of magnitude (depending on the nuclei) by transferring the magnetization of unpaired electron spins (polarizing agents) to the surrounding nuclear spins. Utilizing emerging high frequency microwave technologies, optimized polarizing agents together with state of the high resolution solid-state NMR instrumentation and methods, we plan to develop original magnetic resonance experiments at high magnetic fields. This technique should allow bringing down the NMR detection threshold to micro/nano-molar concentration, studying larger molecular systems and performing multidimensional experiments orders of magnitude faster. The project will lead to numerous interdisciplinary applications to illustrate the potential of DNP-enhanced NMR to characterize new materials for the nanotechnologies (functionalized nanotubes, molecular wires, etc.), new polymers for energy (CNT embedded in polymers, etc.), and to determine the 3D atomic solid-state structure of biomolecules (membrane proteins, paramagnetic proteins, etc.).";;176803,79;FP7-PEOPLE-IEF-2008;/MC-IEF;COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES;FR;;;"/SCI;/EMP";1;0;0;1;0;0 90135;230817;CLIMED;ONG;FP7-PEOPLE;FP7-PEOPLE-IRSES-2008;FP7;Climate Change, Water and Productivity in the Mediterranean: Capacity Building for Geospatial Modelling;2009-02-01;2011-01-31;;"The aim of this research is capacity building through exchanging young scientist to estimate both hydrological and rates of biogeochemical cycling in order to test hypotheses on the relationship between climate change and ecosystem productivity in the Mediterranean environment. Remotely sensed-data, GIS and process-based simulation models have provided the capability to assess ecological change at broad spatio-temporal scales. The proposed exchange programme can be considered as a chance of connecting the hydrology and the remote sensing communities from Europe and US to develop tools for understanding of climate change consequences using geospatial technologies. The requested EU exchange project pursues a clear application and enables to transfer expertise from science into practice and on the other hand the mutual exchange of knowledge between research groups from Turkey, Germany, England and US. The major focus of the project using geospatial technologies is in two folds: i) Climate change and water management and modelling; Water scarcity and management is a cross-cutting issue in the world. This is especially true in the Mediterranean region where water resources are limited and water issues are the most urgent. Modelling the water, solute and erosion dynamics will be done by means of the J2000 physically based system which will be supported by GIS-analysis and remote sensing; ii) Climate change and the ecosystem productivity; The main steps are, a) Classification, quantification and analysis of land-use, b) Collection of inputs (climate, soil and biotic data) for simulation models, c) Quantification of C-N budgets and simulation of temperature rise scenarios. These topics are interdisciplinary in nature and involve processes that are relevant to biophysical ecology, biogeography, and climate. To study these topics, the research relies heavily on remote sensing, biophysical models of land-atmosphere energy exchange, GIS and statistical methods.";;72000;FP7-PEOPLE-IRSES-2008;/MC-IRSES;UNIVERSITY OF CUKUROVA;TR;;;/EDU;1;0;0;1;0;0 90758;221707;LHC-PHYS;ONG;FP7-PEOPLE;PEOPLE-2007-2-1.IEF;FP7;Testing non-standard Higgs and top-quark production and decay at the CERN's Large Hadron Collider: a collaboration between theory and experiment;2008-08-01;2010-07-31;;This collaborative project is in the area of high energy particle physics phenomenology, with focus on some extensions of the Standard Model. The proposal is a research programme where the applicant's expertise on various theoretical aspects of non-standard Higgs and top-quark production in hadronic collisions is perfectly matched with that available at the host institution. The NExT Institute has in fact several leading world experts on the phenomenology of the Standard Model and beyond at present and future high energy colliders both at theoretical and experimental level (with groups working on the CMS and ATLAS collaborations at the CERN's LHC facility, where the aforementioned studies will take place). More than that, NExT's mission is to promote fundamental research where theorists and experimentalists work together in the process of new physics discovery and the applicant is the ideal catalyser for this, having done so in the past. Hence, this project will produce forefront research, mutually advantageous to both parties, based on a new raw model of young researcher with interdisciplinary skills. We are especially interested in the search for a Higgs boson, the only particle not yet discovered predicted by the SM or extensions thereof. The Higgs boson is potentially the key to answer the fundamental question of why elementary particles have mass. Its search is therefore the primary goal for the LHC. New physics can also be hidden in the top quark though, the heaviest and least known of all particles detected so far, hence our project is also concerned with it. Overall, our goal is to contribute to a better understanding of the world of particle physics, by proposing theoretical models and developing and optmising both Monte Carlo and real data analyses to confirm or disprove them experimentally. This application is ideally timed, as the data taking phase of the experiments at the LHC is due to start in 2007/8.;234536,33;234536,33;FP7-PEOPLE-2007-2-1-IEF;/MC-IEF;UNIVERSITY OF SOUTHAMPTON;UK;;;"/SCI;/EDU";1;0;0;1;0;0 96889;265063;ADVOCATE;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-ITN;FP7;Advancing Sustainable In Situ Remediation for Contaminated Land and Groundwater;2011-04-01;2015-03-31;;This project will develop innovative in situ remediation concepts for the sustainable management of contaminated land and groundwater, as required by the WFD. The proposal has 18 academic and industry partners, with expertise in groundwater remediation issues, ranging from pore-scale processes to field-scale application, as well as technology development, water management/treatment, regulation and policy. The research links lab-scale studies of processes with field-scale evaluation and demonstration of novel technology applications, using state-of-the-art methods. It will develop new scientific understanding, performance assessment tools and decision-making frameworks which advance the use of sustainable in situ remediation for contaminated land and groundwater. The network is support by comprehensive knowledge transfer activities. The aim is for more sustainable treatment, to optimise resource investment in environmental restoration, considering technical, social and economic factors. The network will create a comprehensive training environment for early career scientists and engineers in this field. Each academic institution, in cooperation with the industry partners, is well positioned to support the training and professional development of fellows, through existing research training packages and new activities proposed herein. In addition to formal graduate-level instruction and directed research, an innovative package of training initiatives is offered. These include workshops, summer schools, web-based sharing of research and key outputs across the network, complementary training at partner institutions, practical work secondments with industry partners, and participation at national and international conferences. Graduating fellows will benefit from interdisciplinary cooperation and interaction with all sectors of the environmental management community, providing them with the best preparation for a successful career in either academia or industry.;3445531,18;3445531,18;FP7-PEOPLE-2010-ITN;/MC-ITN;THE UNIVERSITY OF SHEFFIELD;UK;"HYDROGEOTECHNIKA SP ZOO;UNIVERSITE DE LIEGE;VLAAMSE INSTELLING VOOR TECHNOLOGISCH ONDERZOEK N.V.;AKADEMIA GORNICZO-HUTNICZA IM. STANISLAWA STASZICA W KRAKOWIE;HELMHOLTZ-ZENTRUM FUER UMWELTFORSCHUNG GMBH - UFZ;UNIVERSITE DE NEUCHATEL;EIDGENOESSISCHE ANSTALT FUER WASSERVERSORGUNG ABWASSERREINIGUNG UND GEWAESSERSCHUTZ;FEDERAL DEPARTMENT FOR ENVIRONMENT TRANSPORTS ENERGY AND COMMUNICATION;Contaminated Land: Applications In Real Environments";"PL;BE;DE;CH;UK";"/EDU;/NET";1;0;0;1;0;0 91993;235186;INJMCE;ONG;FP7-PEOPLE;FP7-PEOPLE-IEF-2008;FP7;Between Penal Revolution and National Resistances. The Influence of the Napoleonic Judicial Model in Continental Europe (1808-1814);2009-09-01;2011-08-31;;My research project aims to define the principles of the Napoleon judicial model and to evaluate their influence in the European regions annexed by the French Empire: Italy, Belgium, the Netherlands, and the Rhineland. By using a comparative approach, I intend to reexamine the image of imperial justice, which has been conceived as an invariable mass of granite, universal and inflexible, founded on an utilitarian, centralized and authoritarian application of law. Such a sanctification of imperial justice corresponds perfectly to the image promoted by the Napoleonic political system. As we approach the bicentenary of the Codes of 1808 and 1810, it seems necessary to assess the viability of this traditional image by revisiting the practice of imperial justice. Belgium, the Netherlands, the Rhineland and Italy, all show a very different acceptance of the Napoleonic model. Such divergence indicates that the foreign departments did not apply French law in any unilateral way and throws into question the generally propagated representation of a monolithic imposition of the Napoleonic Codes. The aim of this project is, therefore, to evaluate the successes and failures occasioned by the model’s exportation. This question is essential to understand the reasons why Napoleonic justice lastingly influenced numerous European countries, even until the present day. The study of these issues is composed of two aspects: documentary research about the practice of penal jurisdictions in the chosen regions and an organization of international and interdisciplinary meetings on the theme of this research. Through formal discussions with fellow researchers and the organization of an international conference, I wish to deepen and facilitate a common reflection on the heritage and influence of the Napoleonic judicial model in the construction of national penal justices in Continental Europe.;;164526,89;FP7-PEOPLE-IEF-2008;/MC-IEF;EUROPEAN UNIVERSITY INSTITUTE;IT;;;"/SCI;/EMP";1;0;0;1;0;0 103386;298138;CTDPES;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IEF;FP7;The cultural transfer and the diffusion of physical education and sport in Europe, 1918-1945: the Anglo-German case;2013-02-01;2015-01-31;;"This project will explore cultural transfer between European states through a study of the diffusion, adoption and appropriation of physical education and sport. The period chosen for the study covers both the dramatic growth of ‘English’ sports in Germany and the less familiar influences of Germanic traditions of physical education in Britain. During the interwar period the governments of most European countries became involved in the ‘politising’ of sport and physical education, ranging from the formal incorporation of sports associations into the state in Germany to the informal ideology of national consensus in Britain. However, these internal political distinctions provide only a partial explanation of the pattern of European sport; the diffusion of ideas, practices and people was critically important and often challenged received ideas of ‘national’ stereotypes and traditions. The first part of the project focuses on the reciprocal German and British influences in two areas: the different models and policies for individual and competitive sport and the parallel process of mass educational and health reform through physical education derived from Germany. The second part examines the networks of co-operation and interchange between athletes, officials and the public across national frontiers in this period of rapid internationalisation that have been neglected and deserve full exploration as part of a wider understanding of the complex process of cultural transfer itself. The researcher has chosen the host university on the basis of its excellence in the interdisciplinary approach of Anglo-British issues and in consultation with her supervisor, who is a world-leading figure in the field. The realisation of this ambitious project requires a wide knowledge in European sports history and the capacity to use knowledge and methods from other disciplines such as political science, sociology and languages. The project’s main sources are located in Berlin and London.";231547,2;231547,2;FP7-PEOPLE-2011-IEF;/MC-IEF;HUMBOLDT-UNIVERSITAET ZU BERLIN;DE;;;/SCI;1;0;0;1;0;0 101184;283615;HOWCOME;ONG;FP7-IDEAS-ERC;ERC-SG-SH2;FP7;The Interplay Between the Upward Trend in Home-Ownership and Income Inequality in Advanced Welfare Democracies;2012-02-01;2017-05-31;;"This research project is the first comprehensive interdisciplinary study into the so far unrecognised interplay between two major social trends of the post-war period: the upward trend in income inequality, and the increase of owner-occupation. Using a comparative perspective, the project aims at constructing a unified account by means of a systematic analysis of: 1) the ‘driving’ forces of both social trends; 2) the ways in which the upswing in income inequality and the expansion of home-ownership might reinforce or counteract each other and hence lead to a redistribution of social and economic risks; 3) how the statistical relationships between variables at the macro-level play out in diverse institutional settings, looking through a more in-depth historical-comparative lens; 4) how the macro-level relationships between both social trends are negotiated by households and individuals as their housing, labour market and family trajectories unfold; 5) how households and individuals negotiate between their perceptions of the economic benefits and risks associated with home-ownership and the ‘real-life’-opportunities and constraints; and 6) how these norms have changed over time as a result of increased income inequality and/or increasing home-ownership rates. Answers will be provided by means of an innovative multi-method and cross-nationally comparative research design. In four subprojects, I will look at these issues through various lenses, using diverse methods of analysis. I take a longitudinal-historical approach, focussing on the post-war era. My scope ranges from large-scale quantitative analysis of country-level data and of individual retrospective and prospective housing, labour and family trajectories to a comparative in-depth case study of institutional developments in a selection of countries. Different analytical approaches are combined in all proposed subprojects.";1200396;1200396;ERC-2011-StG_20101124;/ERC-SG;STICHTING KATHOLIEKE UNIVERSITEIT BRABANT;NL;UNIVERSITEIT VAN AMSTERDAM;NL;/SOC;1;0;0;1;0;0 90178;229825;HEPHAESTUS;ONG;FP7-REGPOT;REGPOT-2008-1-01;FP7;Hellenic Philosophy, History and Environmental Science Teaching Under Scrutiny - He.P.H.a.E.S.T.U.S;2009-04-01;2012-03-31;;The Programe of History, Philosophy and Didactics of Science and Technology originates from two initially complementary teams, the History and Philosophy of S&T Team this for the Didactics of Science. The merge was brought through the acknowledgment that there is a strong need for science to be reestablished in society and engage its stakeholders. This goal is to be accomplished through state of the art research using an interdisciplinary approach. Since 2000, the team has developed into one of the most promising research teams in Southeastern Europe, as can be certified by the following achievements: The team has published two peer reviewed scientific Journals (in Greek and English), a regional Newsletter, 21 books (in Greek, English, French and Chinese) and has co-edited three special issues of international Journals and has published about 250 articles. It has completed 13 research projects with Greek and European partners, has created a prominent science Museum, has organized 14 Symposia and Conferences, organizes a summer seminar, has created a state-of-the-art website and has established an important international network. A SWOT report has identified the team as an excellent regional research unit, and has pointed the following main weaknesses: Unmobilized human resources, lack of experience in museology and public science communicating, lack of European strategic partnerships. In order to fully exploit its capabilities (human potential, science Museum) and therefore contribute through science and society activities to the regional sustainable development, the team plans: two way secondments with excellent European research units to establish twinning, recruitments, a series of conferences, workshops and seminars, equipment acquirement and dissemination and promotional activities using the capacities of the new science Museum.;1054146,4;831765,6;FP7-REGPOT-2008-1;/CSA-SA;ETHNIKO IDRYMA EREVNON;EL;;;/SCI;1;0;0;1;0;0 99153;269182;META;ONG;FP7-PEOPLE;FP7-PEOPLE-2010-IRSES;FP7;Materials Enhancement for Technological Applications;2011-06-01;2015-05-31;http://centronast.it/meta-project-description;"META (Materials Enhancement for Tecnological Applications) aims to address the fundamental new challenges related to the development of new functionally structured materials and to gain a deep understanding of the structure and dynamics of nanostructured matter on multiple length and time scales. Basic science investigation will be driven by the accomplishment of technology development for nanodevices through experimental and theoretical interdisciplinary studies, aimed at endowing materials with specific local properties. Two types of devices will be investigated: DNA planar architectures exploitable as “mother boards” for self-assemblage of functional components to build functional nanodevices at negligible production cost and devices based on interface-enhanced charge conductivity where the understanding of the interplay on a nanometric scale between ionic conductivity and local physico-chemical properties will be exploited for the development of micro Solid Oxide Fuel Cells (?SOFCs). META goal is to establish a strong collaborative network between research centres in the EU (Italy, Slovakia) and in the USA. Such collaboration is addressed to tackle the variety of scientific and technological issues raised by enhancement and engineering of materials functional properties both at the nano and meso scale. Several bilateral visits, training workshops and meetings are planned with the framework of the project. Education will also be an important issue in this project, since exchange of graduate students and the opportunity of creating a joint PhD initiative is programmed. META will thus amplify the collaborative links between the EU and the USA giving European Scientists the opportunity of achieving rapid access to world top laboratories. The project meetings and conferences will attract scientists from other universities and industrial companies which would be highly beneficial for the present partner institutions and ERA in whole.";548100;403200;FP7-PEOPLE-2010-IRSES;/MC-IRSES;UNIVERSITA DEGLI STUDI DI ROMA TORVERGATA;IT;UNIVERZITA KOMENSKEHO V BRATISLAVE;SK;"/EMP;/SOC";1;0;0;1;0;0 101473;290025;MEDIASRES;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-ITN;FP7;Novel Statistical Methodology for Diagnostic/Prognostic and Therapeutic Studies and Systematic Reviews;2012-01-01;2015-12-31;;Novel statistical methodology promises to greatly facilitate development of approaches for personalised medicine. While state-of-the-art statistical techniques have already advanced clinical trials and diagnostic/prognostic studies as the major source of evidence in clinical medicine, increasing availability of molecular techniques holds an even greater promise. However, for leveraging such information for individualised diagnosis/prognosis, and treatment, the corresponding complex structures have to be adequately modelled and results have to be aggregated by corresponding advanced meta-analytic approaches. The main goal of the project is to establish a joint research-training programme by an interdisciplinary and intersectorial network for providing early-stage researchers with deep insight into cutting-edge statistical methodology. The research area of statistical methodology for diagnostic/prognostic and therapeutic studies and systematic reviews is well suited for early-stage training purposes, as it comprises a wide range of theoretical and applied biostatistical tools that need to be mastered, further developed, and translated into clinical research and practice. Europe-wide exchanges will also be ensured to meet the need for mobility in today’s globalised society. Further career relevant knowledge and skills will be provided through a structured design of education. The early-stage researchers will be trained according to an individually supervised, comprehensive and complementary programme. The structure of these activities is based on the training-through-research approach of the network. The collaboration of leading biostatistical experts will stimulate the discovery of promising statistical methodology useful for the design and analysis of clinical research. The integration of full industry partners and clinical advisors in the network enables optimal conditions for research driven by application, which will ensure tangible benefits of the programme.;3935114;3935114;FP7-PEOPLE-2011-ITN;/MC-ITN;UNIVERSITAETSKLINIKUM FREIBURG;DE;"ACADEMISCH ZIEKENHUIS LEIDEN;GLAXOSMITHKLINE RESEARCH AND DEVELOPMENT LTD.;NOVARTIS PHARMA AG;UNIVERSITAET BERN;KOBENHAVNS UNIVERSITET;LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE;H. LUNDBECK AS;UNIVERSITETET I OSLO;UNIVERSIDAD DE VIGO";"NL;UK;CH;DK;NO;ES";"/LIF;/SCI";1;0;0;1;0;0 103628;299288;HARMOFIRE;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IEF;FP7;Harmonic Mode-locked Fibre Lasers;2012-11-15;2014-11-14;;"'Stabilized mode-locked fibre lasers (MLFLs) are important for a range of applications such as optical communications, frequency metrology, medical imaging, micro machining and femtochemistry. MLFLs are cost-efficient, easy to fabricate, have all-fibre design and high output powers. The key aims of the project are: (a) training of Mrs. Habruseva in the fast growing field of fibre lasers; and, (b) development of cost-efficient stable ultra-fast harmonic mode-locked fibre lasers (HMLFLs) for a range of applications. The interdisciplinary training includes fibre components design, fabrication, advanced modelling and implementation, polarization characterization and communication tests, where the host has a crucial expertise. Tatiana will gain additional expertise and knowledge in applications of fibre lasers, laser technologies and modelling through one-month placements at academic and industrial co-hosts. The multidisciplinary activities include supervision and teaching experience, complimentary courses on the project and knowledge management, research funding, proposal writing, and others. In the first year the Fellow will perform modelling and experimental study of HMLFLs, design and fabrication of fibre optics components, assembling of novel device for polarization control and study of HMLFLs with carbon nanotubes and nonlinear polarization evolution. During the second year the Fellow will study stabilization of HMLFLs. These studies will include research on coupled fibre lasers and development of novel methods for noise suppression. Training outcomes will broaden the Fellow’s areas of expertise, enhance her leadership and organisation qualities, and hence will have a great impact on her future career as an independent researcher. Stabilized MLFLs will enable increased performance and reduced complexity of optical networks; they will benefit European community in social, research and economical aspects through contribution to communication technologies.'";209033,4;209033,4;FP7-PEOPLE-2011-IEF;/MC-IEF;ASTON UNIVERSITY;UK;;;/SCI;1;0;0;1;0;0 96029;254150;OF-DFT/MCHF;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IEF;FP7;Orbital Free Density Functional Theory: insights from quantum chemistry and atomic physics;2010-10-01;2012-10-31;;"This proposal aims to put me at the forefront of research in two related domains: quantum chemistry and atomic physics. These domains have the same origin in finding solutions to the Schrödinger equation. Although the methods in both domains stem from the same ab initio approach, they departed from their common ground and developed methods specific to their problems. A few decades ago a revolutionary method came to quantum chemistry: Density Functional Theory (DFT). In this theory the electronic density function replaces the traditional, more complicated wave function to describe the electronic structure of molecules. The implications for computational chemistry have been astounding. The successful development of density functionals to evaluate a system's energy, has made DFT a powerful tool, with applications from bio-chemistry to chemical reactivity. It has become the most popular quantum chemical tool. Today's calculations typically use the Kohn-Sham method which implies the introduction of orbitals, departing from the original spirit of the density-only theory. Motivated by their computational attractiveness (linear scaling, no orthonormalization,no Brillouin zone sampling) researchers have taken up the challenge to design orbital free functionals. This project aims towards the construction and evaluation of such orbital free functionals. Since DFT approaches, remarkably, never found their way to atomic physics, where their potential is evident and since ab initio methods from atomic physics still provide the highest quality density functions (corresponding to an eigenstate), the objectives in this project propose a synergy of concepts, methods and fundamental aspects in both fields. For the successful execution of this interdisciplinary proposal, milestones have been identified which, with the appropriate training, based on the experience and knowledge on functional development of Professor Tozer, is expected to lead to high quality publications.";172903,2;172903,2;FP7-PEOPLE-2009-IEF;/MC-IEF;UNIVERSITY OF DURHAM;UK;;;"/SCI;/EDU;/ITT";1;0;0;1;0;0 103349;298436;DYNAMIC;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IOF;FP7;DYNamic feedbacks of climate impacts on current Adaptation and Mitigation Investment Choice;2012-11-01;2014-10-31;;"This projects proposes a novel framework to modeling the economic consequences of climate change impacts and the induced policy responses, in terms of both mitigation and adaptation strategies at regional scale. To accomplish this task, state-of-the-art IAMs will be modified to include (1) The causal chain between sectoral and regional economic activity and emissions; (2) The climate change feedbacks induced by temperature increase on the different economic sectors and regions; (3) The optimal policy response in terms of mitigation; (4) The optimal policy response in terms of regional and sectoral adaptation. This is a challenging task because of the different nature of adaptation and mitigation and the need of combining optimization with a regional/sectoral detail in a general equilibrium framework, but feasible. Integrating adaptation strategies in an optimization framework will allow to quantify adaptation needs under different mitigation and climate change damage scenarios and to study cross-sectoral spillovers and interactions between the two policy responses, with a sectoral resolution. The project proposed is intrinsically interdisciplinary, requiring a clear understanding of the scientific basis for estimating climate impacts and the skill to combine rigorous empirical analysis with judgment and assumptions in order to cope with incomplete or incommensurate data. The work will be articulated in three main activities: (1) Model development and coding; (2) Data gathering; and (3) Numerical exercises. The expected impact of this research is high because it will develop a roadmap that will serve the future research on induced regional adaptation in a macroeconomic framework.";186389,1;186389,1;FP7-PEOPLE-2011-IOF;/MC-IOF;FONDAZIONE ENI ENRICO MATTEI;IT;;;/SCI;1;0;0;1;0;0 89621;209653;MLTSRMSRFID;ONG;FP7-PEOPLE;PEOPLE-2007-4-3.IRG;FP7;Machine Learning-Based Test Solutions for Reliable Mixed-Signal/RF Integrated Devices;2007-11-01;2011-10-31;;This project aims to develop test strategies for mixed-signal/radio-frequency (RF) integrated devices using machine learning. The proposed efforts will be directed to two main areas, namely (a) the on-line test of mixed-signal/RF circuits when they are embedded in a System-on-Chip (SoC) or a System-in-Package (SiP) that demands high reliability and (b) the testing of RF micro-electro-mechanical systems (MEMS). The key novelty of this interdisciplinary project lies in the amalgamation of concepts from machine learning with state-of-the-art practices in very large-scale integration (VLSI) design and test, in order to address emerging and open-ended test challenges.;100000;100000;FP7-PEOPLE-2007-4-3-IRG;/MC-IRG;INSTITUT POLYTECHNIQUE DE GRENOBLE;FR;;;"/SCI;/COO";1;0;0;1;0;0 87332;220281;PHOTORUACD;ONG;FP7-PEOPLE;PEOPLE-2007-2-1.IEF;FP7;Novel Photodissociable Ruthenium-Based Anticancer Drugs;2008-07-01;2010-06-30;;The discovery of cisplatin, cis-diamminedichloroplatinum(II), as an anticancer drug is a landmark of modern inorganic medicinal chemistry. Platinum drugs are the best-selling antitumor drugs in the world and they are effective in treating a variety of cancers. During the last decade, the search for new anticancer compounds has been widened to other transition metals. Ruthenium complexes in particular have shown considerable promise because of their rich synthetic chemistry, the range of oxidation states, the common octahedral geometry, and finally also because of their rich photochemistry. The fundamental goal of this project is to investigate the possibility of developing new types of hybrid ruthenium-based chemotherapeutic drugs that can be activated by irradiation with low-energy light. When irradiated these molecules form reactive aqua species and, at the same time, release biologically active ligands. The ligands can interfere with the cell cycle at a number of targets, while the metal-containing aqua species inhibit mitosis by binding to DNA. The proposed approach can lead to development of milder, more specific, and tunable drugs which can decrease the negative side-effects of chemotherapy. Inorganic and organic synthetic methodologies, advanced spectroscopic and analytical techniques will be used together with biochemical and medical methods to pursue the objectives of the project. The multi- and interdisciplinary nature of the research will prompt the applicant to acquire practical and theoretical skills on chemical biology and medical chemistry, to improve his independent thinking and leadership qualities, enhancing his scientific competencies and helping the applicant to attain an independent position.;178307,05;178307,05;FP7-PEOPLE-2007-2-1-IEF;/MC-IEF;THE UNIVERSITY OF WARWICK;UK;;;"/SCI;/EDU";1;0;0;1;0;0 91070;229445;STANIB;ONG;FP7-IDEAS-ERC;ERC-AG-SH4;FP7;Space, Time and Number In the Brain;2009-07-01;2014-06-30;;The primary aim of this project is to establish in Pisa a European Centre of Excellence dedicated to frontier, interdisciplinary research of human perception. The research will focus primarily on the human visual system (and its development), but will also investigate key issues of cross-sensory integration. The Institute of Neuroscience has been a leading centre of visual research since its inception in the 1970s, when the multidisciplinary approach of Lamberto Maffei (physiologist) and Adriana Fiorentini (psychophysicist) made seminal and highly influential contributions to many aspects of human and animal vision. In recent years, the focus of the institute has veered towards developmental neurobiology. This project aims to reestablish a cognitive visual neuroscience section within the institute, dedicated to multidisciplinary research into human perception, using modern, non-invasive experimental techniques, such as psychophysics, evoked potentials, neuro-imaging and neuro-computation. The PI has been highly active in cognitive visual neuroscience for thirty years, publishing 150 publications on diverse aspects of perception, including motion perception, colour, space, and vision during saccadics. The planned research builds on these themes, aiming at achieving a firmer understanding of perceptual processes. New topics will also be tackled, such as cross-modal integration between the senses, the perception of event duration and the sense of number estimation, or numerosity. The research will be multi-disciplinary, using psychophysical, neuro-computational and neuro-imaging techniques. Particularly exciting will be the application of state-of-the-art high-field imaging to these important research questions. The establishment of this centre would be fundamental for Italian and European neuroscience in providing a laboratory of critical mass to focus the existing expertise, and to train young scientists within a long-standing tradition of excellence.;2376000;2376000;ERC-2008-AdG;/ERC-AG;UNIVERSITA DEGLI STUDI DI FIRENZE;IT;"CONSIGLIO NAZIONALE DELLE RICERCHE;Fondazione Stella Maris";IT;/MED;1;0;0;1;0;0 91877;235626;PALEOCARB;ONG;FP7-PEOPLE;FP7-PEOPLE-IOF-2008;FP7;Role of the marine carbon cycle in the climate system;2009-07-01;2011-12-31;;"The general topic of the proposal is the study of the marine carbon cycle and its role in the climate system by driving atmospheric CO2. The investigation of this interaction is vital to understanding the key feedbacks operating in the present-day Earth system. The specific research objectives are to determine at a global scale during key climatic intervals i) the composition and main sources of organic carbon in marine sediments; ii) the relative fluxes of organic carbon from various sources to sediments through time and space; and iii) to relate the relative roles of certain marine carbon cycle processes to changes in atmospheric CO2 concentrations. The approach proposed is to undertake a paleoclimatic study combining geochemical measurements in marine sediments with mathematical simulation experiments, using a 3D climate model with a coupled carbon cycle module. The goal of the project is to obtain quantitative information on marine carbon cycle processes using an interdisciplinary approach. The main reconstruction tools are biomarker proxies, as they provide direct information on the carbon cycle, being carbon based molecules. Three time periods of interest have been selected for the study to represent i) conditions equivalent to present (Holocene); ii) a different response of the climate system to practically the same external forcing (Pliocene); and iii) extreme climatic conditions (LGM). The biomarker data will be contrasted against the carbon model results to seek its validation, and obtain new observational bounds to determine the sensitivity of the Earth’s climate to CO2, with the perspective of improving the Earth system model when used in the assessment of future climate changes. Training will be directed towards acquiring new skills in isotopic techniques to analyze organic matter in marine sediments, and the use of biogeochemical models. Additional skills will be obtained on management, career development, innovation, planning, and change management.";;270169,92;FP7-PEOPLE-IOF-2008;/MC-IOF;UNIVERSITAT AUTONOMA DE BARCELONA;ES;;;"/COO;/EDU";1;0;0;1;0;0 90439;235005;NITRICOS;ONG;FP7-PEOPLE;PEOPLE-2007-2-2.ERG;FP7;Nitrogen removal in coastal sediments: molecular microbial ecology of nitrate reducing bacteria;2009-03-16;2012-07-16;;Eutrophication of estuarine and coastal ecosystems due to increased anthropogenic inputs of nitrogen is an increasing problem. Benthic microbial processes can in part alleviate this by removing a significant part of the load. Nitrate in marine sediments can be removed by two main functional groups of bacteria. Bacterial denitrifiers reduce nitrate or nitrite to gases subsequently lost from the aquatic environment, while nitrate ammonifiers reduce nitrate to ammonium that remains in the system. In addition, a novel process, anammox can also remove significant amounts of N in certain environments. However, a product of denitrification is the greenhouse gas nitrous oxide. Understanding the benthic processes involved in the removal of nitrogen, or the formation of nitrous oxide, is important for the management and reduction of nutrient load to coastal waters and greenhouse gases emissions. Although denitrification has been studied extensively, the other two processes and the factors that regulate the competition between these groups of bacteria remain largely unknown. Objectives of the project is to (1) link the distribution of gene abundance coding for key enzymes in the benthic nitrate reducing community and relate these to process rates and (2) study the environmental factors that influence the competition between the different functional groups of nitrate reducing bacteria. To accomplish this, we will apply modern molecular (eg. real time PCR) and biogeochemical (eg. stable isotopes, microelectrodes) techniques in an interdisciplinary way. The results will allow to test the hypotheses that changes in the availability of electron acceptors and donors result in differences in the distribution of functional genes and groups of nitrate reducers and that differences in rates and relative importance of key nitrogen processes along an estuarine gradient are related with changes in the expression of the corresponding functional genes.;45000;45000;FP7-PEOPLE-ERG-2008;/MC-ERG;UNIVERSIDAD DE CADIZ;ES;AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS;ES;"/SCI;/EDU";1;0;0;1;0;0 89823;209157;ARIA;ONG;FP7-PEOPLE;PEOPLE-2007-2-2.ERG;FP7;An investigation of the middle atmosphere response to impulsive ozone perturbations;2007-10-01;2010-09-30;;We propose to investigate the impact of impulsive ozone perturbations on the middle atmosphere. Impulsive perturbation experiments of increasing complexity will be performed on a stratosphere-mesosphere model and the radiative and dynamical response systematically investigated under a range of conditions. Satellite observations of transient ozone changes retrieved with a new 2-dimensional algorithm will be compared to reanalysis data and model results. The comparison will help identifying sources of atmospheric variability and estimating the characteristics of extreme responses, aiding current global circulation models and our understanding of observed climate change. The project aims at developing a common strategy for analysing and interpreting model results, reanalysis data and short term satellite observations, identifying meaningful diagnostics to be used in dynamically controlled regions of the atmosphere where large non-linear responses can arise. An interdisciplinary approach is needed and it is possible coupling the expertise of the candidate on model perturbation experiments and transient phenomena developed during the previous EU Research Training Network, with the state-of-the-art MIPAS/ENVISAT retrieval capabilities and chemistry knowledge of the host institute. The continuation and extension of close collaborations developed with other members of the previous network will guarantee a continuous interaction with experts of middle atmospheric modelling, stratosphere-troposphere coupling, ion-chemistry modelling and transient luminous events.;45000;45000;FP7-PEOPLE-2007-2-2-ERG;/MC-ERG;ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA;IT;;;"/SCI;/EDU";1;0;0;1;0;0 100129;282101;IMPLANT;ONG;FP7-IDEAS-ERC;ERC-SG-LS9;FP7;Silicon transport proteins in biological nanoscience and synthetic biology;2011-10-01;2016-09-30;;This interdisciplinary proposal will investigate whether the activity of a unique family of membrane transport proteins can be harnessed to develop novel strategies for the bioinspired fabrication of nanoscale materials and provide new directions in synthetic biology. Silicon transporters (SITs) are integral membrane proteins that were first identified in the diatoms, single–celled eukaryotic algae that surround themselves with a cell wall of hydrated silica. The biosynthesis of this ‘glass house’ depends upon the uptake of silicic acid, the soluble form of silica, from the environment. The SITs bind silicic acid with high affinity and transport it across the cytoplasmic membrane into the cell. Under this proposal the SITs will be recombinantly expressed and purified before being reconstituted into synthetic liposomes. The resulting proteoliposomes will be energized to drive SIT-dependent transport of silicic acid into the interior lumen. Since the lumen has dimensions on the nanometer length scale and attolitre volume, the proteoliposomes will act as discrete nanoreactors for the synthesis of silica nanoparticles. Using SIT proteins to deliver silicic acid to the growing nanoparticle offers an unprecedented degree of tunable kinetic control over the synthetic conditions that, together with the lumen microenvironment, may induce novel particle morphologies or properties. This principle will be extended in two further directions. First, encapsulating preformed inorganic nanoparticles in the liposome lumen will lead to the formation of core-shell nanoparticles with a functional core and passive silica shell. Using SITs to control the supply of the synthetic precursor will provide unparalleled tight control over the thickness of the silica shell. A second element will create a diatom protocell by incorporating silica-condensing peptides into the lumen in order to generate silica nanostructures. This will establish a unique new methodology for nanoscale synthesis.;1487476;1487476;ERC-2011-StG_20101109;/ERC-SG;UNIVERSITY OF BRISTOL;UK;;;"/ABI;/BIO;/LIF;/MED;/MBI";1;0;0;1;0;0 94774;250098;WEG;ONG;FP7-IDEAS-ERC;ERC-AG-LS8;FP7;Wild Evolutionary Genomics;2010-09-01;2016-08-31;;150 years since the Origin of Species, we do not know how natural selection acts at the level of the genome in natural populations in ecological time, but elucidation is within reach. This study will investigate natural selection, and the genome's response to it, in unprecedented detail by combining two resources. The Soay sheep population on the island of Hirta, St. Kilda, Scotland is one of the most thoroughly phenotyped wild animal populations in the world and already the subject of internationally famous interdisciplinary research. The recently developed International Sheep Genomics Consortium 60K chip identifies 38,777 single nucleotide polymorphisms in Soay sheep. We will genotype 5,000 Soays for these SNPs. We will first analyse the data to test the effect of realised relatedness and inbreeding coefficients on trait heritabilities, genetic correlations and inbreeding depression. We predict that all estimates will increase, generating much increased power for more complex studies. Second, we will identify genome regions harbouring quantitative trait loci (QTL) and inbreeding depression and genotype additional sheep at SNPs in haplotypes predicting this variation. We will subject these regions to intensive analyses to understand their genetic effects, the action of selection on them and their response to selection. Finally, we will count the recombination events in each parent during the creation of each offspring and conduct a comprehensive analysis of sources of individual variation in recombination, the first of its kind in a wild population.;2500000;2500000;ERC-2009-AdG;/ERC-AG;THE UNIVERSITY OF EDINBURGH;UK;;;"/BIO;/LIF";1;0;0;1;0;0 102765;298841;BIOBRIDs;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IEF;FP7;Hierarchical Electroactive Hybrids exploiting Biological Motifs (BIOBRIDs);;;;"We here propose a new approach to the formation of Hierarchical Electroactive Hybrids exploiting Biological Motifs, which will provide new strategies and tools for control that will define future bottom-up 3D construction of materials in the field of functional nanomaterials for nanoelectronics. Functional electroactive oligo(aniline)s, combined with guanine hydrogen-bonding units, will be combined with single-stranded DNA block copolymers in rationally designed ways, so that information encoded in the biological materials will control spatial placement and orientation, interactions and level of functionality in three dimensions within the formed complex and hierarchical superstructures. This groundbreaking approach will utilise combinations of DNA block copolymer (BCP) self-assembly, electroactivity and encoded self-assembly, and will open unexplored avenues in the priority areas of nanotechnology, nanoelectronics and advanced materials through its interdisciplinary and multidisciplinary approach. This proposed research will rely on modern synthetic protocols of organic chemistry, chemicophysical analyses of optoelectronic properties and structure-property interplay, self-assembly in the solid state, device fabrication and testing. It is expected that the outcomes of this proposed research will impact across these disciplines, and contribute knowledge to a high priority area for both society and the research community within the EU and beyond. This fellowship and project will be an important step forward in the research career of Dr. Dasgupta, who has experience and a very strong track record in the synthesis and assembly of functional molecular architectures and supramolecular aggregation. Dr. Dasgupta will therefore be enabled, through this Marie Curie fellowship, to systematically investigate this highly relevant research area that has been left unexplored to date, and thus develop his independent scientific career fully.";209033,4;209033,4;FP7-PEOPLE-2011-IEF;/MC-IEF;UNIVERSITY OF BRISTOL;UK;;;/SCI;1;0;0;1;0;0 105776;289714;SELFORG;ONG;FP7-IDEAS-ERC;ERC-AG-PE3;FP7;Self Organization in Cytoskeletal Systems;2012-04-01;2017-12-31;;"The requirements on the eukaryotic cytoskeleton are not only of high complexity, but include demands that are actually contradictory in the first place: While the dynamic character of cytoskeletal structures is essential for the motility of cells, their ability for morphological reorganisations and cell division, the structural integrity of cells relies on the stability of cytoskeletal structures. From a biophysical point of view, this dynamic structure formation and stabilization stems from a self-organisation process that is tightly controlled by the simultaneous and competing function of a plethora of actin binding proteins (ABPs). The ABPs can be classified to regulate (1) the polymerisation and depolymerisation kinetics of the individual filaments, (2) the structure of the network by crosslinking and bundling the filaments and (3) the dynamic reorganisation and contraction mediated by molecular motors. The major goal is to obtain a sound physical understanding of cellular self organizing principles, by successively increase the complexity of the experimental system in a bottom up approach. Three work packages are defined: (i) the microscopic mechanism of the interaction of ABPs with actin filaments on the treadmilling behaviour of actin. (ii) the effect of confinement, hydrodynamic flow and crosslinking proteins in a 2D high density motility assay and (iii) developing a reconstituted 3D active gel composed of actin filaments and crosslinking molecules. To this end, we will introduce and combine established and new biophysical and biochemical methods and interdisciplinary approaches, with a major emphasis on quantitative imaging and analysis techniques. The outcome of the proposed research will have important consequences and impact in fields ranging way beyond biophysics. Direct implications in rheology, polymer physics, material sciences and cell biology are evident, but also new aspects for the construction of novel biomaterials can be expected.";2285532;2285532;ERC-2011-ADG_20110209;/ERC-AG;TECHNISCHE UNIVERSITAET MUENCHEN;DE;;;"/PSE;/ELM;/NNT";1;0;0;1;0;0 97852;266765;PMELT;ONG;FP7-IDEAS-ERC;ERC-AG-PE5;FP7;New Frontiers in Protein-based Nanomaterials;2011-03-01;2016-02-29;;We propose to undertake an ambitious 5 year interdisciplinary programme that introduces a fundamentally new paradigm in protein-based nanomaterials research. The new approach involves two main project themes based respectively on fundamental studies on the structure, function and properties of molten protein polymer surfactant nanoconstructs, and the development of these novel nanomaterials as smart fluids, biotechnological devices and health care products. This proposal represents a new and adventurous area of work for the PI, and will allow unprecedented access to a novel class of nanomaterials with controllable architectures, unique physical properties and inherent biological functionality. In so doing, the work will open up promising new avenues of bionanomaterials research and offer significant advantages over current methods for producing protein-based nanomaterials at extremely high concentration and dosage. In general we expect the research programme to pioneer new frontiers in fundamental research and generate significant economic and societal impact as nanomaterials become increasingly integrated into medical and technological products, and new commercial markets based on nanoscience are discovered.;2168862;2168862;ERC-2010-AdG_20100224;/ERC-AG;UNIVERSITY OF BRISTOL;UK;;;"/PSE;/MAT;/IND";1;0;0;1;0;0 97129;260920;BLUELEAF;ONG;FP7-IDEAS-ERC;ERC-SG-LS8;FP7;The adaptive advantages, evolution and development of iridescence in leaves;2011-01-01;2016-07-31;;Iridescence is a form of structural colour which changes hue according to the angle from which it is viewed. Blue iridescence caused by multilayers has been described on the leaves of taxonomically diverse species such as the lycophyte Selaginella uncinata and the angiosperm Begonia pavonina. While much is known about the role of leaf pigment colour, the adaptive role of leaf iridescence is unknown. Hypotheses have been put forward including 1) iridescence acts as disruptive camouflage against herbivores 2) it enhances light sensing and capture in low light conditions 3) it is a photoprotective mechanism to protect shade-adapted plants against high light levels. These hypotheses are not mutually exclusive: each function may be of varying importance in different environments. To understand any one function, we need a interdisciplinary approach considering all three potential functions and their interactions. The objective of my research would be to test these hypotheses, using animal behavioural and plant physiological methods, to determine the functions of leaf iridescence and how the plant has adapted to the reflection of developmentally vital wavelengths. Use of molecular and bioinformatics methods will elucidate the genes that control the production of this potentially multifunctional optical phenomenon. This research will provide a pioneering study into the generation, developmental impact and adaptive significance of iridescence in leaves. It would also answer questions at the frontiers of several fields including those of plant evolution, insect vision, methods of camouflage, the generation and role of animal iridescence, and could also potentially inspire synthetic biomimetic applications.;1118378;1118378;ERC-2010-StG_20091118;/ERC-SG;UNIVERSITY OF BRISTOL;UK;;;"/BIO;/LIF";1;0;0;1;0;0 95789;254810;CESADIC;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IIF;FP7;Crystal Engineering of Self-Assembled Diblock Copolymers with a Crystalline Core-Forming Block;2010-06-01;2012-05-31;;A series of complex, hierarchical micelle architectures such as block co-micelles have recently been prepared from crystalline-b-amorphous diblock copolymers using living, crystallization-driven polymerizations in solution. In this proposal the fundamental issues behind this novel process will be investigated. We propose to perform and interpret detailed experiments designed to allow us to understand the issues arising from the formation and behaviour of micelle architectures such as cylinders formed by diblock copolymers with a crystalline, core-forming polyferrocenylsilane block. The proposed studies of cylindrical micelles with a crystalline metallopolymer core will allow us to accumulate new fundamental knowledge in the field of polymer crystallization that can be used for predicting the behaviour of other crystalline blocks. For example, we will explore the extension to polylactide block copolymer materials. A variety of future applications in polymer and materials science and nanoscience are anticipated. This interdisciplinary and multidisciplinary research proposal requires a wide range of skills and combines the expertise of the applicant (polymer crystallization and morphology) with that of the host laboratory (polymer chemistry, materials chemistry, and nanoscience). The proposed research will bring a promising young researcher to the UK for 2 years before his return to Taiwan.;240289,6;240289,6;FP7-PEOPLE-2009-IIF;/MC-IIF;UNIVERSITY OF BRISTOL;UK;;;"/SCI;/EDU;/ITT";1;0;0;1;0;0 94870;253332;PROMID;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IEF;FP7;Pronouns of Medieval Italian Dialects;2010-04-01;2011-06-30;;This project will examine the pronominal systems of Medieval Italian Dialects on the basis of a scrutiny of 13th and 14th centuries texts. It will represent a significant contribution both to the field of Italo-Romance linguistics and, more widely, to the general linguistics community, by adopting an interdisciplinary approach that interfaces traditional philological and dialectological studies with recent advances in morphological and syntactic theory. The data will be firstly sifted on the basis of rigorous philological criteria in order to exclude from the sample of texts those containing misleading phenomena due to the influence of other (prestigious) dialects or the intervention of later copyists. Then the data will be classified and stored into a relational database, which allows efficient and rapid comparison of morphological and syntactic variation. In particular, the project will exploit an innovative data management system based on an inventory of specific tags that capture unambiguously the grammatical properties of each sentence. This allows us to organize the data according to a set of linguistic features so as to maximise the possibilities of comparison and enhance the capacity to find meaningful correlations among morpho-syntactic phenomena. On the basis of these features, this system will indeed retrieve not only a specific phenomenon in different texts, but also its specific characteristics and the co-occurrence of distinct phenomena/properties. The database will finally provide an organized set of data that can be readily retrieved and compared in order to allow the extraction of material for articles, presentations, and a comprehensive grammar of MID personal pronouns to be prepared during the last phase of the research.;173403,2;173403,2;FP7-PEOPLE-2009-IEF;/MC-IEF;UNIVERSITY OF BRISTOL;UK;;;"/SCI;/EDU;/ITT";1;0;0;1;0;0 96272;257158;ACTIVENP;ONG;FP7-IDEAS-ERC;ERC-SG-PE3;FP7;Active and low loss nano photonics (ActiveNP);2010-10-01;2015-09-30;;This project aims at designing novel hybrid nanophotonic devices comprising metallic nanostructures and active elements such as dye molecules or colloidal quantum dots. Three core objectives, each going far beyond the state of the art, shall be tackled: (i) Metamaterials containing gain materials: Metamaterials introduce magnetism to the optical frequency range and hold promise to create entirely novel devices for light manipulation. Since present day metamaterials are extremely absorptive, it is of utmost importance to fight losses. The ground-breaking approach of this proposal is to incorporate fluorescing species into the nanoscale metallic metastructures in order to compensate losses by stimulated emission. (ii) The second objective exceeds the ansatz of compensating losses and will reach out for lasing action. Individual metallic nanostructures such as pairs of nanoparticles will form novel and unusual nanometre sized resonators for laser action. State of the art microresonators still have a volume of at least half of the wavelength cubed. Noble metal nanoparticle resonators scale down this volume by a factor of thousand allowing for truly nanoscale coherent light sources. (iii) A third objective concerns a substantial improvement of nonlinear effects. This will be accomplished by drastically sharpened resonances of nanoplasmonic devices surrounded by active gain materials. An interdisciplinary team of PhD students and a PostDoc will be assembled, each scientist being uniquely qualified to cover one of the expertise fields: Design, spectroscopy, and simulation. The project s outcome is twofold: A substantial expansion of fundamental understanding of nanophotonics and practical devices such as nanoscopic lasers and low loss metamaterials.;1494756;1494756;ERC-2010-StG_20091028;/ERC-SG;UNIVERSITAT LINZ;AT;;;"/PSE;/ELM;/NNT";1;0;0;1;0;0 90624;235892;CHROMATIN MOTILITY;ONG;FP7-PEOPLE;FP7-PEOPLE-IEF-2008;FP7;An innovative system to impose altered features on a defined chromosome region and investigate its movement by fluorescence microscopy in the nucleus of a cell;2009-05-01;2011-04-30;;Our objective is to provide world-class research and training in the field of Life Sciences. Our innovative project applies interdisciplinary methods to identify new paradigms therefore contributing to the knowledge-based economy and society. Scientifically, the project involves cutting-edge microscopy in fission yeast to characterize the relationship between different chromatin features and their position in the nucleus. We will integrate distinct scientific approaches to obtain breakthroughs in the field. All research activities are in compliance with fundamental ethical principles. Further the project will be carried out in a laboratory where gender equality is encouraged, currently there are ten women in a group of fifteen. With respect to the training: we provide a comprehensive experimental work-plan which is designed to enhance the researchers career development and the diversification of his abilities at an advanced level. This is achieved by sharing reagents and expertise in collaborative exchanges as well as in meetings and workshops. We also present a timetable of the anticipated progress with milestones, promoting proactive project management. The diversity of valuable skills acquired will certainly benefit the researcher and support professional maturity in attaining an independent position. The candidate is a motivated and enthusiastic experienced researcher with an excellent academic and research track record. He developed his skills and scientific training on an international basis, convinced that mobility is central to the open-minded requirement of fundamental discoveries. He will join the well-known laboratory of Professor Robin Allshire in Edinburgh, who is recognized as world-leader in the field of chromosomal biology. Overall the project is a collaborative effort set in the leading research University in Scotland with state-of-the-art infrastructures and facilities, contributing to Europe’s excellence and attractiveness.;171300,62;171300,62;FP7-PEOPLE-IEF-2008;/MC-IEF;THE UNIVERSITY OF EDINBURGH;UK;;;"/SCI;/EMP";1;0;0;1;0;0 88727;221855;PICK1 AND DAT;ONG;FP7-PEOPLE;PEOPLE-2007-2-1.IEF;FP7;Regulation of dopamine transporter function by the PDZ domain protein PICK1;2008-06-01;2010-05-31;;The dopamine transporter (DAT) belongs to the family of Na\/Cl- dependent neurotransmitter transporters and is responsible for rapid termination of dopaminergic signaling by mediating reuptake of dopamine (DA) from the synaptic cleft. The DAT is target for widely abused psychostimulants, such as amphetamine and cocaine, as well as modification in DAT activity has been associated with severe brain disorders like Parkinson’s disease, schizophrenia and attention deficit hyperactivity disorder (ADHD). An increasing number of proteins have been identified as interaction partners of the DAT but the functional implications of the interactions are poorly understood. Here we propose to investigate the molecular significance of the interaction between DAT and the PDZ domain protein PICK1. Based on a series of preliminary data we propose that binding of PICK1 via its PDZ domain to the DAT C-terminus operate to regulate uncoupled DAT mediated currents. Notably, these currents are likely to modulate the excitability of dopaminergic neurons and thereby the overall activity of the dopamine system. We hypothesize that PICK1 mediated regulation of these currents either involves enhanced DAT phosphorylation due to PICK1 mediated recruitment of protein kinase Ca or modulation of intramolecular interactions in the transporter molecule. We will test our hypotheses by employing an interdisciplinary strategy that combines the expertise of the applicants with those of the host laboratory and involves a broad spectrum of methods including patch clamp measurements, bioimaging and molecular biological procedures. We expect that the project will lead to significant improvement of our understanding of DAT regulation and thereby provide an important framework for future discovery of novel therapeutic strategies against diseases characterized by dopaminergic dysfunction.;201923,71;201923,71;FP7-PEOPLE-2007-2-1-IEF;/MC-IEF;KOBENHAVNS UNIVERSITET;DK;;;"/SCI;/EDU";1;0;0;1;0;0 93090;235791;EFH-GIS;ONG;FP7-PEOPLE;FP7-PEOPLE-IEF-2008;FP7;The identification and mapping of Essential Fish Habitats using Geographic Information Systems (EFH-GIS);2010-01-01;2012-05-01;;Effectively managed fisheries are more likely to be sustainable and combine a healthy biodiverse marine ecosystem with an economically viable and competitive fisheries industry. Such fisheries management goals cannot be achieved if, for instance, the managed fish species do not have access to sufficient suitable habitat. The identification and spatiotemporal mapping of Essential Fish Habitats (EFHs) represent fundamental scientific tasks of the spatial component of fisheries management, a component that has often been neglected in previously enforced fisheries policies. The EFH-GIS (‘Essential Fish Habitats - Geographic Information Systems’) project aims to support the spatial component of fisheries management, by applying an interdisciplinary environmental approach to the mapping and designation of EFHs in the eastern Mediterranean Sea, an area that supports commercially important fisheries. Through five main research objectives, this two-year fellowship will see (1) the updating and enrichment of an existing GIS database, which (2) will be used to map ocean processes (e.g. eddies) to be fed into (3) the modelling of habitat for several commercially important species of fish. This knowledge will then be used (4) to identify over- and under-exploited fishing areas and also in a preliminary study to design a network of Marine Protected Areas (MPAs), which are sanctuaries to protect EFHs. The project intends to contribute to the long-term preservation of fisheries resources, as well as (5) increasing scientific knowledge and public awareness of the eastern Mediterranean marine ecosystem. The specialised training received as part of the fellowship, as well as the contribution made to scientific knowledge in this field, will greatly contribute to the fellow in terms of career and professional development, but also to Europe in terms of excellence and competitiveness.;146876,08;146876,08;FP7-PEOPLE-IEF-2008;/MC-IEF;HELLENIC CENTRE FOR MARINE RESEARCH;EL;;;"/SCI;/EMP";1;0;0;1;0;0 104046;300859;ADMIRATION;ONG;FP7-PEOPLE;FP7-PEOPLE-2011-IEF;FP7;"""ADvanced Mid-InfraRed broadband laser sources for Application in Telecommunications, bIo-photonics, metrOlogy and few-cycle pulse generatioN""";2012-03-01;2014-02-28;;"'The project aims to advance the emerging field of mid-infrared (mid-IR) photonics towards widespread interdisciplinary application in life sciences, chemistry and physics. Despite the importance of mid-IR radiation for various research areas, most current mid-IR laser sources are not well matched to application demands and have yet to achieve the level of flexibility, compactness, reliability and ease of use of their near-IR and visible counterparts. ADMIRATION proposes to overcome these shortcomings by developing novel high brightness, broadband coherent and spectrally uniform ultrashort pulse laser sources based on supercontinuum generation (SCG) in specialty optical fibers. In particular, we target the design, fabrication and experimental implementation of optimized mid-IR SCG sources for 4 key applications areas: - high spectral density broadband transmission sources for next-generation telecommunication networks - non-invasive early detection of diseases by molecular fingerprinting in breath analysis - highly stable and efficient frequency comb generation for metrology - high performance few-cycle pulse amplification and high harmonic generation for ultrafast imaging of the carbon structure of bio-molecules The project will address technological challenges in soft glass microstructured fiber design and fabrication to adapt fiber-based mid-IR SCG sources to the challenging application demands, following similar such demonstrations by the applicant during his PhD work in silica fibers for near-infrared and visible spectral ranges. ADMIRATION is therefore fully aligned with FP7 research objectives by developing “photonics technologies, components and (sub-) systems driven by key applications and social needs” and directly addresses target outcomes of the 2011/12 Work Program, including “bio-photonics for early, fast and reliable diagnosis of diseases” as well as 'future-proof telecommunications networks and systems' development.'";200371,8;200371,8;FP7-PEOPLE-2011-IEF;/MC-IEF;UNIVERSITY OF SOUTHAMPTON;UK;;;/SCI;1;0;0;1;0;0 95030;256428;NANOWEB;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-RG;FP7;Development of Functional Nanofibers by Electrospinning;2010-05-01;2014-04-30;;Electrospinning is a technique for producing nanofibers by creating a continuous filament by exposing a polymer solution or polymer melt to very high electrical fields. Due to its versatility and cost effectiveness, electrospinning has gained wide use recently to produce functional nanofibers from different materials, which include polymers, polymer blends, ceramics, sol-gels and composite solutions. Electrospun nanofibers and their nanowebs have several remarkable characteristics such as very large surface-to-volume ratio, pore sizes in nano range, unique physical properties along with the design flexibility for chemical/physical functionalization by incorporating specific additives into nanofibers. The unique properties and specific functionalities of such nanofibers/nanowebs make them favorable candidates in many applications areas such as medical/biotechnology, filtration and membrane technology, functional textiles, sensors, energy, composite materials, etc. Nanofibers/nanowebs from various types of natural and synthetic polymers can be easily produced by electrospinning, yet, improvements and new functionalities are always desired in order to enhance the properties of these electrospun nanofibers/nanowebs and broaden their application areas. Herein, it is proposed to fabricate functional polymeric nanofibers/nanowebs containing specific additives (cyclodextrins, textile additives, antibacterials, etc) by using electrospinning technique. The aim of this project is to produce new functional electrospun nanofibers/nanowebs and investigate their properties for the development of multi-functional nanofibrous materials for applications in filtration, functional textiles, medical/biotechnology, etc. The research proposed here has an interdisciplinary nature in the field of chemistry, materials science, textile, biology and engineering.;100000;100000;FP7-PEOPLE-2009-RG;/MC-IRG;Bilkent Üniversitesi;TR;;;/SCI;1;0;0;1;0;0 95368;256535;EOUNETWORKS;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-RG;FP7;Product End-of-Use Management Networks;2010-10-01;2014-09-30;;"Increasing rates of consumption and disposal result in products that arrive to their end-of-use stage while retaining economic value and suitable for reuse and recycling. Although theoretically promising, relatively few circular supply loops are self-sustaining in practice. This evidence raises the question of why voluntary economically viable product end-of-use management network of agents that are involved in such activities (i.e., recycler, remanufacturer, consumer, collector, etc.) are not operating on a large scale yet. In response, I argue that such networks are complex systems and not well understood as yet. Therefore, in this research I propose to advance the knowledge and understanding of how such networks of product end-of-use (EoU) agents emerge and evolve in response to market conditions, regulation, and changes in each other’s corporate strategy. I propose to combine industrial ecology and operations management concepts using agent-based models with data from the U.S. and Israel as a tool to examine environmental and economic performance patterns of each agent and the overall network (i.e., the market). The socio-economic rationale for this research is the need for better understanding how to design product EoU collection and processing networks in order to increase dramatically the economic and environmental efficiency of such systems. This research is valuable to policy makers formulating and revising product EoU regulations and to the different EoU agents looking to gain competitive advantage while complying with regulations. It combines methods from the industrial ecology and management disciplines and such interdisciplinary approach to a very timely manner problem aligns well with the work program goals. The researcher had partnered with multiple researchers and industrial contacts to collaborate on this research; these relationships will enable her to disseminate the findings and turn them into applied solutions.";100000;100000;FP7-PEOPLE-2009-RG;/MC-IRG;TEL AVIV UNIVERSITY;IL;;;/SCI;1;0;0;1;0;0 94212;237266;ANCEPS;ONG;FP7-PEOPLE;FP7-PEOPLE-IIF-2008;FP7;evolutionAry traNsitions: Chemical Ecology of Parasitic Societies;2010-03-01;2012-02-29;;"The interdisciplinary study of chemical communication has developed into a cutting edge field of science that can address key questions on the organization of life at both the cellular and the organismal level. The study of communication in insect societies and their social parasites has played a pivotal role in these developments. However, suitable model lineages with a sufficient number of evolutionary transitions between normal social living and social parasitism are uncommon and even fewer have been thoroughly studied. This proposal intends to make such a key model system available for study in Europe. Megalomyrmex ants are chemical warriors, dispensing volatile venom alkaloids (VAs) by waving their stings (i.e. gaster flagging) as they enter another ant species’ nest or during competition; the former are derived social parasites (parasites of a society), while the latter are predatory species. Both use gaster flagging as a ‘warning shot’, announcing their presence to hosts or competitors. If the host does not allow infiltration, the invader will attack and kill. Infiltration can be accomplished as just described (i.e. chemical weaponry) or through the alteration of cuticular hydrocarbons (CHCs) (i.e. surface chemistry) using chemical mimicry and/or insignificance. I intend to decipher the chemical code of communication and manipulation of Megalomyrmex ants, linking behaviours observed to their chemical ecology. I will 1) test three infiltration strategy hypotheses using behavioural experimentation, 2) identify relevant chemical compounds, and 3) examine the results in an evolutionary context with phylogenetic hypothesis testing. Using a unique model system I pioneered, I will gain focused training in a leading laboratory in Europe which will enhance my job opportunities and future collaboration with Europe, transfer unique knowledge to the EU, and encourage a shift in the research on social parasitism towards a more comparative approach.";;296089,38;FP7-PEOPLE-IIF-2008;/MC-IIF;KOBENHAVNS UNIVERSITET;DK;;;"/SCI;/EMP";1;0;0;1;0;0 95265;249440;STIMOS;ONG;FP7-IDEAS-ERC;ERC-AG-SH4;FP7;Syllables and the Timing of Speech;2010-10-01;2016-11-30;;"Project summary: The project develops an integrative symbolic-dynamical framework for gaining a fundamental understanding of the relation between qualitative spoken language form, also known as phonological form, and the continuous speech movements and acoustics in which this form is realized. The empirical domain is syllables. The syllable is a central unit of spoken language, mediating between lower-level properties of individual sounds and higher-level prosody. In its first aim, the proposed research develops modelling methods for rigorously evaluating the relation between theoretically posited syllabic parses and experimental data, from Arabic and English, acquired with the new 3D EMA device. In a second aim, formal analytical methods are developed for understanding the relation between posited abstract phonological organization and its measurable phonetic indices. Using a combined symbolic-dynamical approach, the analytical component fully embraces the task of relating continuous data and qualitative theory, a fundamental problem in present day cognitive science. As a consequence, the project enables a system-level, quantitative understanding of how categorical organizational principles of linguistic systems may be supported by or emerge from statistical properties of the lower-levels in which linguistic form is conveyed. The interdisciplinary theoretical, experimental and mathematical approach proposed here has not been attempted before for spoken language. The outcome would be a unified explanatory framework for linguistic competence, experimental data and statistics. The project’s significance and relevance to the “Ideas” program lies in the centrality of the core problem it addresses for the language and mind frontier. In linguistics and cognitive science, a fundamental challenge has been the lack of a formal substrate for dealing with the duality of the symbolic and the continuous. The development of an integrative framework for exploring the relation between qualitative phonological form and continuous data will open up new perspectives for researching both language and the human mind. In addition, the proposed research has significant potential long-term benefits for language development, impairment and reading. Because syllabic organization is language-specific and because we know that this organization conditions the timing of articulatory movements, syllables provide a key construct for studying the link between articulatory timing and linguistic ability in both healthy and patient populations.";1120705;1120705;ERC-2009-AdG;/ERC-AG;UNIVERSITAET POTSDAM;DE;LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN;DE;/MED;1;0;0;1;0;0 95190;254819;BOOKSREADERSSPIT;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IEF;FP7;BOOKS AND READERS BETWEEN THE IBERIAN AND ITALIAN PENINSULAS TOWARDS AMERICA (SEVILLE AND FLORENCE);2010-05-01;2012-04-30;;"The first aim of my project is to study the development of a new kind of readers in Europe in the Early Modern period, those who were interested in works of humanities (understood as the erudition and fine writing), and the influence of cultural transferences on it. Until this moment, these humanities works have been studied from the perspective of its lenguage, its authors or its bibliographical characteristics, but the questions proposed in this project are different. An interdisciplinary perspective is compulsory, a perspective in which economic, social and cultural history are combined; because the objetive is not only to identify those who were their readers, but also to know how they assimilated and responsed to these texts. These readers seem to have been members of the urban oligarchy. The starting point for this project will be the Seville readers living during the Spanish Golden-Age (XVIth-XVIIth centuries), this study should be done overcoming the local view with a global perspective of analysis. In that sense, the close cultural relation between Spain and Italy in the Early Modern period, leads us to study the role that the emulation of Italy played in the formation of “cultured” Spanish readers. This offers us the possibility to evaluate the role played by the cultural exchange with Italy in the appearance and development of this type of readings, as well as compare Spanish and Italian libraries. This research will allow us to evaluate the degree in which the Spanish colony in Italy served as a bridge or road for the transmission of works of humanities to the Iberian Peninsula, and from there to the Americas. Therefore, the main objetive of my project is to study the cultural tranference in Europe (and the Americas) through the mechanisms of the circulation of books and texts. Those mechanims can be professional (booksellers) or non-professional (I will pay speciall attention, for example, to the correspondence between erudites).";214572,4;214572,4;FP7-PEOPLE-2009-IEF;/MC-IEF;EUROPEAN UNIVERSITY INSTITUTE;IT;;;"/SCI;/EDU;/ITT";1;0;0;1;0;0 93908;246976;PAHS;ONG;FP7-IDEAS-ERC;ERC-AG-PE9;FP7;The Role of Large Polycyclic Aromatic Hydrocarbon molecules in the Universe;2010-05-01;2015-04-30;;Strong emission features dominate the IR spectra of the interstellar medium of the Milky Way, galaxies in the local Universe and out to redshifts of ~3. These features are generally attributed to IR fluorescence of large Polycyclic Aromatic Hydrocarbon (PAH) molecules pumped by UV photons. These species must be abundant, ubiquitous, and an important component of the ISM. However, despite extensive experimental and theoretical efforts, no specific PAH or even classes of PAHs have been unambiguously identified. Hence, we do not really know the intrinsic physical and chemical properties of these species and therefore cannot quantify their role in the Universe. I propose a highly interdisciplinary program combining observational, theoretical, and experimental studies to determine the IR emission characteristics of large PAH molecules, their origin and evolution, and their influence on the Universe around us. The proposed program will analyze interstellar PAH spectral maps obtained with Spitzer and ISO and relate the spatial variations in the spectral diversity to variations in the characteristics of the radiation field and the physical conditions of these regions that will be obtained with Herschel. This observational program will be aided by an innovative laboratory program that will measure the IR characteristics of large, astrophysically relevant PAH molecules in the gas phase and by a modelling program of the emission characteristics of these PAHs in space. In addition, the photochemistry of gaseous PAHs will be studied in the laboratory using novel techniques, allowing us to model the chemical evolution of PAHs and their reaction products in the interstellar medium. In this way, key astronomical questions involving interstellar PAHs can be addressed.;2383980;2383980;ERC-2009-AdG;/ERC-AG;UNIVERSITEIT LEIDEN;NL;;;"/PSE;/AER;/SPA";1;0;0;1;0;0 95034;256504;CELL POLARITY;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-RG;FP7;Role of Microtubule Polarity and Polarized Membrane Traffic in Directed Cell Migration;2010-05-01;2014-04-30;;The ability of cells to polarize is crucial for development, wound healing, and neurotransmission. As many cellular polarity factors play central roles in disease (e.g. cancer, neurological dysfunction) understanding the molecular basis of cell polarity is of great importance to the biomedical sciences. One central aspect of cell polarity involves the regulation of the cytoskeleton and membrane-trafficking machinery, leading to the delivery of specific proteins and lipids to distinct cellular subdomains. This polarized membrane traffic seems important for cells that exhibit local cell growth, including migrating cells. Using advanced imaging approaches I showed that migrating cells preferentially deliver their secretory vesicles towards the leading edge (i.e. the front), and that this polarized delivery depends on intact microtubules (MTs). But how MTs and polarized membrane traffic contribute to cell migration remains unclear. Recent work on wound-edge migrating cells has identified factors that lead to distinct MT polarity phenotypes, i.e. MT stabilization and centrosome orientation, both of which could contribute to bias membrane traffic towards the front of the cell by either forming specialized vesicular tracks or by positioning secretory organelles in front of the nucleus. I will use interdisciplinary cell biological and state-of-the-art imaging and screening approaches to 1) investigate the mechanism of how MT polarity and polarized membrane traffic contribute to directed migration using known factors, 2) identify membrane trafficking factors that play a role in directed migration using automated image-based screening and 3) investigate the role of common traffic/migration factors in polarized membrane traffic and MT polarity. Further, I will implement ‘super-resolution’ microscopy to image the nanoscale localization of polarity factors in greater detail. These studies are aimed toward a more comprehensive understanding of cell polarity.;100000;100000;FP7-PEOPLE-2009-RG;/MC-IRG;FREIE UNIVERSITAET BERLIN;DE;;;/SCI;1;0;0;1;0;0 94687;258334;EVOBODY;CLO;FP7-ICT;ICT-2009.8.10;FP7;New Principles of Unbound Embodied Evolution;2010-06-01;2011-08-31;;Evolutionary computation is an efficient optimizing and solution-generating mechanism inspired by biological evolution. It has been successfully applied in many branches ofengineering, business, artificial biological (synthetic biology) and technological (robotics) systems. Evolution-based models of computation in a broader sense are now ``invading' newinterdisciplinary research areas in innovative fields within bio-chemistry, on-chip factories, reconfigurable and evolvable hardware, molecular computing, and pervasive adaptivesystems. The resulting systems are permanently driven by internal and/or external forces with long-term evolve-ability, unbound developmental processes, and very strong embodiment. Traditional evolutionary computing does not provide knowledge about such novel systems. The given proposal targets evolutionary and related multi-disciplinary communities, such as bio-inspired, adaptive, bio-synthetic ones, which use mechanisms of evolutionary computation. The main goal is to facilitate identification and formulation of novel research topics on the field of unbound developmental and self-developmental evolutionary processes, embodied in different real systems. Such systems are estimated to have an essential impact on science, technology and society in next years, this support activity aims to connect different communities to create also an awareness of these global trends and to focusresearchers on fundamental challenges and their impact.;249560;166000;FP7-ICT-2009-5;/CSA;VERENIGING VOOR CHRISTELIJK HOGER ONDERWIJS WETENSCHAPPELIJK ONDERZOEK EN PATIENTENZORG;NL;UNIVERSITAET STUTTGART;DE;"/EVA;/INF;/COO;/ITT";1;0;0;1;0;0 88905;215840;PARTNER;ONG;FP7-PEOPLE;PEOPLE-2007-1-1-ITN;FP7;Particle Training Network for European Radiotherapy;2008-10-01;2012-09-30;;A Particle Training Network for European Radiotherapy (PARTNER) will be established in response to the critical need for reinforcing research in ion therapy and the training of professionals in the rapidly emerging field of hadron therapy. This is an interdisciplinary, multinational initiative, which has the primary goal of training researchers who will help to improve the overall efficiency of ion therapy in cancer treatment, and promote clinical, biological and technical developments at a pan-European level, for the benefit of all European inhabitants. This need has particular urgency since two particle therapy facilities will soon become operational in Heidelberg (HIT, Germany) in early 2008, and in Pavia (CNAO, Italy) later in 2008. These are the first dual particle therapy centres to be built in Europe but others have been recently approved in Austria, France, and Germany, and there are longer-term plans for advanced accelerator systems in Spain and UK. PARTNER brings together ten academic institutes and research centres of excellence, the two leading European companies in particle therapy, IBA and Siemens, and a recently established SME enterprise specialised in the area of radiation treatment planning solutions. All partners are known world-wide in the diverse but complementary fields associated with particle therapy: clinical, radiobiological and technological. Thus the network covers a unique set of competencies, expertise, infrastructures and training possibilities. The ultimate goal of hadron therapy is to deliver more effective treatment to the cancer patient. Potentially hadron therapy can have a very major impact on health of citizens. The context of a new technique and a dynamic research program in an area of great societal demand offers outstanding training opportunities for future careers of the young researchers.;5601450;5601450;FP7-PEOPLE-2007-1-1-ITN;/MC-ITN;EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH;CH;"FONDAZIONE CENTRO NAZIONALE DI ADROTERAPIA ONCOLOGICA;ION BEAM APPLICATIONS SA;GSI HELMHOLTZZENTRUM FUER SCHWERIONENFORSCHUNG Gmbh;UNIVERSITAETSKLINIKUM HEIDELBERG;FONDAZIONE PER ADROTERAPIA ONCOLOGICA - TERA;KAROLINSKA INSTITUTET;EBG (Entwicklungs- und Betriebsgesellschaft) MedAustron GmbH;UNIVERSITY OF SURREY;SIEMENS AKTIENGESELLSCHAFT";"IT;BE;DE;SE;AT;UK";"/EMP;/SOC;/EDU";1;0;0;1;0;0 92635;242958;MECHWNTSIGNALS;ONG;FP7-IDEAS-ERC;ERC-SG-LS3;FP7;Mechanisms of Wnt Signaling Initiation;2009-12-01;2014-11-30;;Wnt proteins dictate critical cell growth and lineage decisions during development and in adult tissue homeostasis. Inappropriate activation of Wnt signalling is a frequent cause of cancer. The earliest events that occur after Wnts bind their receptors at the cell surface, such as receptor endocytosis and recruitment of cytoplasmic effectors, are decisive for downstream gene activation but the underlying mechanisms by which these events process and tune the Wnt signal remain poorly understood. The key objective of this proposal is to resolve critical molecular events that drive initiation of the Wnt cascade by focusing on two central questions: How does protein trafficking control Wnt signalling initiation? What molecular mechanisms underlie Wnt-induced formation and activation of multiprotein complexes? I will take a unique approach combining advanced live cell imaging and high resolution immuno-electron microscopy with sophisticated peptide chemistry, gene silencing and biochemistry to dissect early Wnt signalling events at the level of isolated molecules, in cultured cells and in complex tissues of living animals. With the proposed interdisciplinary work I expect to uncover where key Wnt signalling steps occur, which proteins are involved, how they direct protein complex assembly, trafficking and turnover and how these events control transmission of the Wnt signal. Mechanistic insight in how Wnt signals are transmitted is vital to understand how pathway specificity and sensitivity is controlled. Basic insight in these processes will be of utmost importance for the design of strategies to interfere with Wnt signalling in cancer.;1513800;1513800;ERC-2009-StG;/ERC-SG;UNIVERSITAIR MEDISCH CENTRUM UTRECHT;NL;;;"/BIO;/LIF";1;0;0;1;0;0 93885;247153;DARCLIFE;ONG;FP7-IDEAS-ERC;ERC-AG-PE10;FP7;Deep subsurface Archaea: carbon cycle, life strategies, and role in sedimentary ecosystems;2010-04-01;2015-03-31;;Archaea are increasingly recognized as globally abundant organisms that mediate important processes controlling greenhouse gases and nutrients. Our latest work, published in PNAS and Nature, suggests that Archaea dominate the biomass in the subseafloor. Their unique ability to cope with extreme energy starvation appears to be a selecting factor. Marine sediments are of crucial importance to the redox balance and climate of our planet but the regulating role of the deep biosphere remains one of the great puzzles in biogeochemistry. The unique and diverse sedimentary Archaea with no cultured representatives, so-called benthic archaea, are key to understanding this system. Their presumed ability to degrade complex recalcitrant organic residues highlights their relevance for the carbon cycle and as potential targets for biotechnology. I propose to study the role of benthic archaea in the carbon cycle and in the deep biosphere and to explore their life strategies. This task requires an interdisciplinary frontier research approach at the scale of an ERC grant, involving biogeochemistry, earth sciences, and microbiology. Central to my research strategy is the information contained in structural and isotopic properties of membrane lipids from benthic archaea, an area of research spearheaded by my lab. In-depth geochemical examination of their habitat will elucidate processes they mediate. Metagenomic analysis will provide a phylogenetic framework and further insights on metabolism. At the Archaeenzentrum in Regensburg, we will grow model Archaea under a set of environmental conditions and examine the impact on cellular lipid distributions in order to develop the full potential of lipids as proxies for studying nearly inaccessible microbial life. Attempts to enrich benthic archaea from sediments will complement this approach. This frontier research will constrain the role of benthic archaea in the Earth system and examine the fundamental properties of life at minimum energy.;2908590;2908590;ERC-2009-AdG;/ERC-AG;UNIVERSITAET BREMEN;DE;UNIVERSITAET REGENSBURG;DE;"/PSE;/ENV;/EAR";1;0;0;1;0;0 92675;240186;MIGRANT;ONG;FP7-IDEAS-ERC;ERC-SG-PE6;FP7;Mining Graphs and Networks: a Theory-based approach;2009-12-01;2015-05-31;;In this project we aim at formulating enhancing theoretical foundations for the emerging field of graph mining. Graph mining is the field concerned with extracting interesting patterns and knowledge from graph or network structured data, such as can be found in chemistry, bioinformatics, the world wide web, social networks etc. Recent work has shown that many standard data mining techniques can be extended to structured data and can yield interesting results, but also that when applied to complex real-world data, these standard techniques often become computationally intractable. In this project we aim at providing a better understanding of the complexity of the tasks considered in the field of graph mining, and at proposing techniques to better exploit the properties of the data. To this aim, we will bring together insights from the fields of data mining, graph theory, learning theory and different application fields, and add our own original contributions. Key features of the methodology include the ground-breaking integration of insights from graph theory in data mining and learning approaches, the development of efficient prototype algorithms, and the interdisciplinary collaboration with application domain experts to validate the practical value of the work, This potential impact of this project is significant, as it will be the first systematic study of the theory of graph mining, it will provide foundations on which later research can build further and it will have applications in the many domains with complex data.;1716066;1716066;ERC-2009-StG;/ERC-SG;KATHOLIEKE UNIVERSITEIT LEUVEN;BE;;;"/PSE;/IPS";1;0;0;1;0;0 92461;240080;NUCLEOPOLY;ONG;FP7-IDEAS-ERC;ERC-SG-PE5;FP7;DNA Block Copolymers: New Architectures and Applications;2009-11-01;2014-10-31;;With our contributions to DNA block copolymers (DBCs), we have opened a new field of interdisciplinary research at the intersection of polymer chemistry, biology and nanoscience. Within this proposal, we intend to apply our expertise with linear DBCs to new nucleocopolymer architectures ranging from star polymers to DNA networks. Our efforts will not only explore new covalently-bonded polymer topologies but also extend the range of self-assembled supramolecular structures accessible with DBCs. Current progress in this direction has yielded spherical and rod-like DBC micelles. In this proposal we further envisage membranes and vesicles generated by macromolecular DNA amphiphiles. A special focus will be the manipulation of the permeability of these structures by hybridization and the insertion of channel proteins. A major part of the proposal addresses potential applications of DBC architectures in the fields of nucleic acid detection and drug delivery. We will produce selective and sensitive nucleic acid probes employing DBCs with highly emissive conjugated polymer segments or based on novel fluorogenic DNA-templated reactions. Plans for potential delivery systems include the establishment of a DBC-based technology platform to allow combinatorial testing of micelle structures equipped with improved targeting, drug loading and stealth functions. For this purpose, the DNA shell of the nanoscopic aggregates will be exploited for its biological activity in the context of antisense and small interfering RNA activity as well as immune stimulation. Finally, we will employ DBC micelles as programmable nanoreactors within the complex environment of living cells and even carry out sequence-specific organic transformations induced by the cell s own messenger RNA;1500000;1500000;ERC-2009-StG;/ERC-SG;RIJKSUNIVERSITEIT GRONINGEN;NL;;;"/PSE;/IPS;/TEL";1;0;0;1;0;0 92214;240002;AFRIVAL;ONG;FP7-IDEAS-ERC;ERC-SG-PE10;FP7;African river basins: catchment-scale carbon fluxes and transformations;2009-10-01;2014-09-30;;This proposal wishes to fundamentally improve our understanding of the role of tropical freshwater ecosystems in carbon (C) cycling on the catchment scale. It uses an unprecedented combination of state-of-the-art proxies such as stable isotope, 14C and biomarker signatures to characterize organic matter, radiogenic isotope signatures to determine particle residence times, as well as field measurements of relevant biogeochemical processes. We focus on tropical systems since there is a striking lack of data on such systems, even though riverine C transport is thought to be disproportionately high in tropical areas. Furthermore, the presence of landscape-scale contrasts in vegetation (in particular, C3 vs. C4 plants) are an important asset in the use of stable isotopes as natural tracers of C cycling processes on this scale. Freshwater ecosystems are an important component in the global C cycle, and the primary link between terrestrial and marine ecosystems. Recent estimates indicate that ~2 Pg C y-1 (Pg=Petagram) enter freshwater systems, i.e., about twice the estimated global terrestrial C sink. More than half of this is thought to be remineralized before it reaches the coastal zone, and for the Amazon basin this has even been suggested to be ~90% of the lateral C inputs. The question how general these patterns are is a matter of debate, and assessing the mechanisms determining the degree of processing versus transport of organic carbon in lakes and river systems is critical to further constrain their role in the global C cycle. This proposal provides an interdisciplinary approach to describe and quantify catchment-scale C transport and cycling in tropical river basins. Besides conceptual and methodological advances, and a significant expansion of our dataset on C processes in such systems, new data gathered in this project are likely to provide exciting and novel hypotheses on the functioning of freshwater systems and their linkage to the terrestrial C budget.;1745262;1745262;ERC-2009-StG;/ERC-SG;KATHOLIEKE UNIVERSITEIT LEUVEN;BE;UNIVERSITE DE LIEGE;BE;"/PSE;/ENV;/EAR";1;0;0;1;0;0 91257;226589;PASSO;ONG;FP7-ENVIRONMENT;ENV.2008.4.2.2.1.;FP7;Participatory Assessment of Sustainable Development indicators on good governance from the Civil Society perspective;2009-05-01;2010-10-31;;"PASSO will assess Sustainable Development Indicators on Good Governance and its cross-cutting features from a social perspective. The starting point will be the list of SDIs adopted in the context of the EU Sustainable Development Strategy on the Good Governance Theme. Alternative sets of governance indicators from international initiatives (e.g. United Nations) will be considered too. These sets of indicators will be subject to a participatory assessment process allowing CSOs members to react to RTD performers, statisticians and experts’ views in an iterative manner. A small interdisciplinary International Expert Group (20 members) composed of both CSOs representatives and experts will be created for a first professional review of the existing indicators. The results of the assessment will be submitted for consultation to a Europe-wide large CSOs network. In parallel, national CSOs consultations in Austria, Belgium, Bulgaria, France, Italy, Romania, Spain and The Netherlands will take place. The consultation process will be reiterated within the IEG first and with the public at large at the end so as to ensure that the outcome of PASSO is built on the consensus among all social actors concerned. The aim of the overall assessment will be: • to appraise the relevance and efficiency of the existing indicators from the Civil society perspective in combination with experts views; • to identify gaps and suggest how to fill them, with possible amendments or development of new indicators; • to produce a priority list of such amendments/new developments based on a multi-criteria assessment of their relevance from the CSOs perspective • to draft recommendations for the improvement of SDS/SDIs.";676365;597360;FP7-ENV-2008-1;/CSA-SA;ISTITUTO DI STUDI PER L'INTEGRAZIONE DEI SISTEMI (I.S.I.S) - SOCIETA'COOPERATIVA;IT;"POUR LA SOLIDARITE ASBL;MISSIONS PUBLIQUES;UNIVERSITAET STUTTGART";"BE;FR;DE";"/SOC;/SDT";1;0;0;1;0;0 92129;245026;PRO-TECH NATURE;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-NIGHT;FP7;Protecting from natural hazards using new technologies. The role of the researcher;2009-06-15;2009-12-14;;Natural hazards are atmospheric, earth or water processes that may damage people, property or other parts of the environment. Many of the effects of existing and predicted natural hazards are made worse by the location of human settlement. Communities spring up on plains, terraces and dune systems that have been created by natural hazards such as floods, earthquake faulting, wave action and changes in sea level. The main natural hazards met in Greece are: coastal flooding, earthquakes, river flooding, rural fires, landslides, erosion, weather (wind and rainfall), disasters caused by climate change. A researcher’s mission is to advance and communicate knowledge on hazards mitigation and disaster preparedness, response, and recovery. Using an all-hazards and interdisciplinary framework, Universities foster information exchange and integration of activities among researchers, practitioners, and policy makers from around the world. They support and conduct research, and provide educational opportunities for the next generation of hazards scholars and professionals. The main aim of all events corresponded to the project “Pro-Tech Nature” is to enhance public recognition of researchers and their role in society and to encourage young people in Greece to embark on scientific career.;32600;25000;FP7-PEOPLE-2009-NIGHT;/CSA-SA;PANEPISTIMIO AIGAIOU;EL;"EIDIKOS LOGARIASMOS EREVNON DIMOKRITEIOU PANEPISTIMIOU THRAKIS SPECIFIC RESEARCH ACCOUNT OF DEMOCRITUS UNIVERSITY OF THRACE;INSTITOUTO TECHNIKIS SEISMOLOGIAS KAI ANTISEISMIKON KATASKEVON";EL;"/SCI;/EDU";1;0;0;1;0;0 92288;236962;NACSA;ONG;FP7-PEOPLE;FP7-PEOPLE-IOF-2008;FP7;North Atlantic Climatic Sedimentary Archives. Provenance and Transport Controls;2010-02-01;2011-08-31;;"North Atlantic deep-water formation is the starting step of the Meridional Overturning Circulation (MOC), which redistributes heat from low to high latitudes. Therefore, this region is a key modulator of Earth climate. Changes in this system by external forcings will easily propagate by the MOC, ultimately impacting global climate. Hence, the North Atlantic sedimentary record is an ideal archive of past climate changes. Paleoclimate reconstructions rely critically in accurate determinations of the sedimentary fluxes and the timescales of the mechanisms that trigger and propagate climate changes, yet important timescales such as the transport time of the sediments are still difficult to determine. U-series isotopes disequilibria provide an effective tool for reconstructing these fluxes and constraining these timescales. The time-dependence of 234U depletion relative to 238U in silt sized sediments provides a measure of the comminution age; the time elapsed since their production and final deposition. This can be used as a proxy for climate-induced changes in provenance and deep-current circulation. This proposal aims to reconstruct a high-resolution record of the comminution age, sediment fluxes and focusing, and post-depositional history of the last glacial cycle of ODP site 984 (Bjorn Drift, S Iceland). This interdisciplinary approach will involve U-series isotopes, magnetic properties, composition and sedimentological characteristics of these sediments. This project will test the hypothesis of an alternating source of sediments from Europe to Iceland in phase with glacial and interglacial periods, respectively, rather than a change in bottom currents activity. At the same time, it will provide further grounds for analyzing the response of this proxy in time-scales ranging from abrupt climate forcings to millennial-scale cyclicity during the last glacial cycle, which will help understand the role of the North Atlantic in the Quaternary climatic variability.";148964,95;148964,95;FP7-PEOPLE-IOF-2008;/MC-IOF;UNIVERSIDAD DE VIGO;ES;;;"/COO;/EDU";1;0;0;1;0;0 91056;228261;SPARSEASTRO;ONG;FP7-IDEAS-ERC;ERC-AG-ID1;FP7;Sparse Representation of Multivalued Images: Application in Astrophysics;2009-10-01;2014-09-30;;Modern imaging instruments generally provide multi-value datasets, which means that for a given image pixel, we do not only have one measurement (such as the intensity) but a set of ancillary data. This could be information on color, but in general this extra data set can also be much more complex. The proposed interdisciplinary project intends to develop the next generation of sparse representation methods for complex multi-valued astronomical data in order to probe the fine structure and extract information in high dimensional astronomical data sets. Objectives: Our project will have three main scientific directions: i) Find new decompositions for sparse representation of complex multi-valued data, ii) develop new scheme for data restoration, component separation, data compression using the new sparse representations and iii) apply the new developed techniques on astronomical data. Originality: New sparse representations for such data set is essential for fundamental progress in a wide range of problem areas where traditional multiscale methods have now run their course. Expected results: Our effort will result in three main deliverables. Theory: Coherent, comprehensive knowledge, showing what can and cannot be accomplished with sparse representation. Tools: A wide range of practical algorithms and a unified, publicly available software environment -- SparseAstro-Lab -- deploying them. Applications: Our main initial focus will be on the analysis of data in astronomy, such as those coming soon from the satellites PLANCK, HERSCHELL or GLAST.;2268600;2268600;ERC-2008-AdG;/ERC-AG;COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES;FR;;;/SCI;1;0;0;1;0;0 92239;239443;ECOGENOMICS;ONG;FP7-PEOPLE;PEOPLE-2007-2-2.ERG;FP7;The evolutionary consequences of inbreeding in natural populations: Genotypic-phenotypic interactions and implications for genetic diversity and evolutionary potential;2009-04-01;2012-03-31;;Studies of processes that maintain genetic variation for fitness are fundamental for understanding evolutionary forces shaping the life histories and phenotypic characteristics of animals. Such processes include evolutionary interactions between population genetic structure and mating system, dispersal patterns and social organization. The interplay between genetic diversity and adaptive evolution ultimately provides the necessary understanding for predicting evolutionary response to environmental change. My research proposal seeks to understand the selective forces underlying the evolution of cooperation and the evolutionary consequences of evolving inbreeding mating systems by merging ecological, genetic and genomic methodologies in a highly integrative and interdisciplinary approach.;45000;45000;FP7-PEOPLE-ERG-2008;/MC-ERG;AARHUS UNIVERSITET;DK;;;"/SCI;/EDU";1;0;0;1;0;0 90789;237720;TWILIGHTZONE;ONG;FP7-PEOPLE;FP7-PEOPLE-IEF-2008;FP7;Into the twillight zone: testing jet launching and collimation engines with near-infrared and (sub-)mm interferometry;2009-05-01;2010-08-31;;The quest for the origin of stars and planets is one of the main thrusts of modern astronomy playing a leading role in the science cases of new instruments and infrastructures, in the ground and space. A major open question in this field is the understanding of the physical mechanisms responsible for the launching and collimation of jets and winds from young stars. Such a mechanism is of wide astrophysical significance as it is thought to operate in young stars, AGNs, micro-quasars and gamma-ray bursts. The remarkable combination of larger angular size and line emission make young stars ideal laboratories for such studies. Wind launching has further dramatic consequences on the angular evolution of the star-disk system and radically changes the planet forming disk properties in the inner disk regions where solar system rocky planets and extra-solar hot jupiters are found. The present research programme aims at the career development of the fellow leading to a position of scientific excellence and autonomy after several years of teaching and administrative duties. The programme is highly interdisciplinary, it combines observational predictions of state-of-the-art MHD models using radiative transfer tools with leading front-line observational techniques exploiting synergies in near-infrared and (sub-)mm interferometry. Such a programme anchors on the match of the fellow profile combined with the outstanding training and scientific capacity of the host. In the short term it will allow direct constraints on the launching and collimation mechanism. Lasting impact will be achieved by equipping the fellow with the capacity to lead scientific programmes in top world infrastructures where Europe has a leading role such as the Very Large Telescope Interferometer and the coming ALMA array. Upon returning to its home institute the fellow will be transferring know-how contributing to the excellence and the integration of peripheral countries in the European research area.;;153690,64;FP7-PEOPLE-IEF-2008;/MC-IEF;UNIVERSITE JOSEPH FOURIER GRENOBLE 1;FR;;;"/SCI;/EMP";1;0;0;1;0;0 91494;234409;MICROTRANCE;ONG;FP7-PEOPLE;FP7-PEOPLE-IOF-2008;FP7;Microbiological Transformation of Anthropogenic Nitrogen in Coastal Environments;2009-05-01;2011-08-31;;The anthropogenic perturbation of the nitrogen cycle has the potential to change the coupling of fundamental element cycles in aquatic ecosystems. Coastal areas as transition zones between land and sea are directly affected by this due to heavy industrialization, dense human colonization, and massive riverine inputs of artificial reactive nitrogen (Nr). In order to better predict the potential impact of increasing Nr supply on the biogeochemistry and ecology of coastal areas and to evaluate the consequences for the adjacent ocean one need to understand the flux of inorganic and organic nitrogen through the lower food web (bacteria to zooplankton). Biological research on a micrometer scale, however, is often limited by methodological drawbacks like e.g. size independent separation of cells and instant rate measurements. MicroTRANCE wants to overcome these constraints by stable isotope tracer experiments, state-of-the-art cell identification and sorting by Flow Cytometry, and highly sensitive rate measurements using Membrane Induced Mass Spectrometry. The proposed interdisciplinary research will cover eutrophicated as well as pristine coastal habitats and includes advanced lab work. This approach will lead to a better insight into nitrogen transformation processes due to a high functional and cellular resolution. The scientific aim of MicroTRANCE is to study the cascading effects of increasing inorganic nitrogen inputs on the linkage between primary production and the microbial loop with respect to the coupling of the nitrogen cycle with carbon and phosphorous in coastal environments. Thus, MicroTRANCE will help to close gaps in our knowledge regarding the flux of reactive nitrogen as urgently recommended e.g. by the International Nitrogen Initiative (INI). Moreover the proposed research contributes to an integrated coastal policy as recently called by the European Commission (Impact Assessment Summary, Brussels, Oct. 2007).;;186068,97;FP7-PEOPLE-IOF-2008;/MC-IOF;ALFRED-WEGENER-INSTITUT HELMHOLTZ-ZENTRUM FUR POLAR- UND MEERESFORSCHUNG;DE;;;"/COO;/EDU";1;0;0;1;0;0 92059;244748;SHAREBRAINS;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-NIGHT;FP7;Interregional Multidisciplinary Researches’ Night Researchers and Citizens in Interaction;2009-05-01;2009-11-30;;"The RN Share Brains will invite all citizens as parent, student, company director, teacher, granny, etc. to spend an academic, educational and entertaining night together with researchers on Friday, the 25th of September, 2009. Based on previous experiences and a high impact reached, the Share Brains can guarantee an attractive, well balanced programme between highly scientific and academic but also popular issues including attractions, fun and entertainment linked to researchers and their work in benefit for all of us. Researchers are given voice and face as they will be put in star roles in spotlights as speakers, performers, guides, animators, singers, show masters, jury members etc. always in interaction with citizens. Improved interactivity and finetuning will be considered real issues here. Share Brains will apply new ways of being interactive during the event, but also during the planning phase and in the awareness campaign; the use of social media, blogs and other digital media will increase the degree of interactive participation and sharing views and visions in advance. It is also the young people and children we want to attract; they will complete the industrial revolution and lead Europe into the phase of knowledge based society. We now live the digital turn and know virtual worlds, but the future research will open doors which we now can not imagine yet. Share Brains will demonstrate how fascinating and highly interesting the work of a researcher can be. People can meet researches as common people, just as “one of us”, they can be met in living labs, on the stages, exhibition places, panel discussions, sofa-corners, around coffee tables and in the streets and on science paths. The Share Brains –project will build up a holistic, interdisciplinary event, a mini-world, where researchers represent technology, economy, humanities, industrial design etc. "Imagine! Create! Innovate! is imperative now. ShareBrains wants to build up a matrix of sharing.";131603,2;85000;FP7-PEOPLE-2009-NIGHT;/CSA-SA;KOUVOLA INNOVATION OY;FI;"PAIJAT-HAMEEN KOULUTUSKONSERNI-KUNTAYHTYMA;LAPPEENRANNAN TEKNILLINEN YLIOPISTO";FI;"/SCI;/EDU";1;0;0;1;0;0 90696;220948;GLYCOPEPTIDES;ONG;FP7-PEOPLE;PEOPLE-2007-2-1.IEF;FP7;“Solid phase synthesis, biophysical study and biological evaluation of cyclic glycopeptides for inhibition of protein protein interactions”;2008-11-06;2010-11-05;;Dr. Jarikote, an Indian national who has recently completed his PhD in Germany and is currently working with Prof. Dr. Paul Murphy. It is proposed that Dr. Jarikote will work on solid phase synthesis of cyclic glycopeptides and their biophysical characterization with a view to generating novel inhibitors of protein-protein interactions, in particular those that involve a-helices. He will also receive training in carbohydrate chemistry, scaffolds, NMR and molecular modelling and their application to the design of bioactive compounds wherever necessary. The biophysical characterisation will also carried out and techniques such as NMR and fluorescence will be used to investigate binding of synthetic ligands to targeted proteins. Such synthetic mimics could have wide pharmaceutical importance as they have potential to be bioavailable mimics of peptides that modulate protein-protein interactions. The proposal is of interdisciplinary nature, collaborating ultimately with physical chemists and cell biologists and will focus on the design, synthesis and biological evaluation of novel proteomimetics or peptidomimetics based on macrocycles comprised of saccharide structures. Mimetics of the surface of the Bak peptide (an alpha-helical peptide) based on glycopeptides will be synthesised on the solid phase and the products will be evaluated for their biophysical properties effects on promoting apoptosis in tumour cells. The solid phase synthesis approach will give rise to rapid access of numerous derivatives of target oriented glycopeptides in short time period. The glycopeptides design will be based on ensuring the presentation of pharmacophoric groups in a spatial orientation that matches that of residues at i, i\4 and i\7 of the relevant ?–helical peptide, in this case the BAK peptide. The solid phase approach will faciliate efficient investigation of a number of pharmacophoric groups that will allow generation of an optimal ligand that mimics the natural peptide.;174784,33;174784,33;FP7-PEOPLE-2007-2-1-IEF;/MC-IEF;NATIONAL UNIVERSITY OF IRELAND GALWAY;IE;;;"/SCI;/EDU";1;0;0;1;0;0 90287;232823;EVOCULTURE;ONG;FP7-IDEAS-ERC;ERC-AG-LS8;FP7;The Evolution of Culture;2009-04-01;2015-03-31;;The capacity for culture is clearly a critical factor underlying the success of our species, but how and why did it evolve? What are the selection pressures that favoured the evolution of cultural capabilities (e.g. social learning, innovation, teaching), and how has selection fashioned these to operate efficiently? The study of such abilities is central to a broad range of disciplines, and significant progress in the scientific understanding of their origin and operation will ripple out to exert considerable influence, both within and outside academia. This project utilises a broad but integrated package of highly innovative empirical and theoretical techniques, including the development of novel analytical tools that allow behavioural researchers to identify social learning and predict the diffusion of innovations, application of potentially revolutionary statistical methods for inferring causal influences on the evolution of brain and culture from correlational data, and a new empirical system providing an unparalleled opportunity to investigate the evolution and biological basis of social learning. I will also organize international competitions to identify effective social learning rules ( tournaments ), in which entrants each propose learning strategies that are pitted against each other in computer simulation, and the most effective wins a prize. Collectively, the projects offer a major step forward in our understanding of human evolution, adaptation and culture and will stimulate considerable interdisciplinary exchange.;2128195;2128195;ERC-2008-AdG;/ERC-AG;THE UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS;UK;;;"/BIO;/LIF";1;0;0;1;0;0 87721;207667;FBRAIN;ONG;FP7-IDEAS-ERC;ERC-SG-PE5;FP7;Computational Anatomy of Fetal Brain;2008-09-01;2013-08-31;;Studies about brain maturation aim at providing a better understanding of brain development and links between brain changes and cognitive development. Such studies are of great interest for diagnosis help and clinical course of development and treatment of illnesses. Several teams have begun to make 3D maps of developing brain structures from children to young adults. However, working out the development of fetal and neonatal brain remains an open issue. This project aims at jumping over several theoretical and practical barriers and at going beyond the formal description of the brain maturation thanks to the development of a realistic numerical model of brain aging. In this context, Magnetic Resonance (MR) imaging is a fundamental tool to study structural brain development across age group. We will rely on new image processing tools combining morphological information provided by T2-weighted MR images and diffusion information (degree of myelination and fiber orientation) given by diffusion tensor imaging (DTI). The joint analysis of these anatomical features will stress the generic maturation of normal fetal brain. We will first rely on mathematical models to allow reconstruction of high resolution 3D MR images in order to extract relevant features of brain maturation. The results issued from this first step will be used to build statistical atlases and to characterize the neuroanatomical differences between a reference group and the population under investigation. From a methodological point of view, our approach relies on an interdisciplinary research framework aiming at combining medical research to neuroimaging, image processing, statistical modelling and computer science. The robust characterization of the anatomical features of fetal brain and the development of a realistic model of brain maturation from biological concepts will come out from the strong interactions between these different research fields.;753393;753393;ERC-2007-StG;/ERC-SG;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FR;;;"/PSE;/IPS;/TEL";1;0;0;1;0;0 89686;219265;ECOFUN;ONG;FP7-PEOPLE;PEOPLE-2007-4-1.IOF;FP7;Analysis of biodiversity changes on structural and functional properties of marine ecosystems under cumulative human stressors;2009-01-01;2011-12-31;;The objective of my research is to quantify how the structure of marine food-webs has changed due to biodiversity changes and develop an understanding of how these changes have impacted ecosystem functioning. To accomplish this objective I will use an interdisciplinary approach applying meta-analysis of historical and recent data on species loss and ecosystem changes, food-web modelling and laboratory experiments. This first trial run approach will provide complementary information on how biodiversity loss resulting from different anthropogenic disturbances such as fisheries exploitation, eutrophication and climate change has affected the network structure and functioning of marine food-webs at different temporal and spatial scales. The study will be divided into four parts: (A) In the first part I will make a synthesis of available data of long term changes on marine biodiversity (species decrease, loss, increase or recovery) under gradients of different human impacts (e.g. exploitation, increase of nutrient loading, habitat loss, temperature rise). I will also record observed/measured consequences of these changes from individual to ecosystem level (e.g. cascading effects, transfer efficiency changes, increase on detritus, oxygen depletion). (B) This data will be then analysed using ecological modelling techniques to explore the consequences of biodiversity changes in food web dynamics in time and space. (C) In parallel, I will develop aquatic microcosm experiments to reproduce observed patterns of human impacts on food webs and quantify ecosystem change. (D) Synthesis data, modelling results and microcosm analysis will be use to quantify general patterns of food web structural and functional changes due to biodiversity change by applying a meta-analysis approach. If I can successfully re-predict present-day food webs, I aim at forecasting past and current trends and develop ecosystem recovery scenarios into the future using modelling and laboratory experiments.;212125,36;212125,36;FP7-PEOPLE-2007-4-1-IOF;/MC-IOF;AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS;ES;;;"/SCI;/COO";1;0;0;1;0;0 87473;207599;COSPSENA;ONG;FP7-IDEAS-ERC;ERC-SG-PE3;FP7;Coherence of Spins in Semiconductor Nanostructures;2008-06-01;2013-05-31;;Macroscopic control of quantum states is a major theme in much of modern physics because quantum coherence enables study of fundamental physics and has promising applications for quantum information processing. The potential significance of quantum computing is recognized well beyond the physics community. For electron spins in GaAs quantum dots, it has become clear that decoherence caused by interactions with the nuclear spins is a major challenge. We propose to investigate and reduce hyperfine induced decoherence with two complementary approaches: nuclear spin state narrowing and nuclear spin polarization. We propose a new projective state narrowing technique: a large, Coulomb blockaded dot measures the qubit nuclear ensemble, resulting in enhanced spin coherence times. Further, mediated by an interacting 2D electron gas via hyperfine interaction, a low temperature nuclear ferromagnetic spin state was predicted, which we propose to investigate using a quantum point contact as a nuclear polarization detector. Estimates indicate that the nuclear ferromagnetic transition occurs in the sub-Millikelvin range, well below already hard to reach temperatures around 10 mK. However, the exciting combination of interacting electron and nuclear spin physics as well as applications in spin qubits give ample incentive to strive for sub-Millikelvin temperatures in nanostructures. We propose to build a novel type of nuclear demagnetization refrigerator aiming to reach electron temperatures of 0.1 mK in semiconductor nanostructures. This interdisciplinary project combines Microkelvin and nanophysics, going well beyond the status quo. It is a challenging project that could be the beginning of a new era of coherent spin physics with unprecedented quantum control. This project requires a several year commitment and a team of two graduate students plus one postdoctoral fellow.;1377000;1377000;ERC-2007-StG;/ERC-SG;UNIVERSITAT BASEL;CH;;;"/PSE;/ELM;/NNT";1;0;0;1;0;0 89616;208841;ECODOM;ONG;FP7-PEOPLE;PEOPLE-2007-4-3.IRG;FP7;Advancing Understanding of Carbon Cycling and Coloured Dissolved Organic Matter Dynamics in European Wetlands & Coastal Ecosystems through integration of observations and novel modelling approaches;2008-05-01;2012-04-30;;This proposal aims at facilitating an efficient and lasting re-integration of Dr Maria Tzortziou in the Hellenic Center for Marine Research (HCMR). The main goal is to initiate a competitive and interdisciplinary research program at HCMR that will advance our understanding of the role that wetlands and tidal marshes play in dissolved organic matter (DOM) dynamics, carbon cycling, photochemistry, biogeochemistry, and water quality changes in coastal margin ecosystems. Specific objectives of the research initiated with EcoDOM include: (i) Characterize landscape-scale variation in the quantity and quality of the dissolved organic compounds exported from different wetlands and coastal tidal marshes in SE Europe, and understand implications of such variation for estuarine biogeochemistry, ecosystem productivity, and water optics. (ii) Develop novel and improved modelling approaches for describing and predicting effects of photochemical processes on DOM quality and degradation. Accurate quantitative description of these effects is prerequisite for improving the accuracy of more general biogeochemical/ecological models of carbon cycling. (iii) Apply a novel radiative transfer model to examine the effects of wetland DOM inputs on underwater light fields. (iv) Link the proposed work to remote sensing applications by developing bio-optical relationships between remotely sensed quantities, DOM optical properties and biogeochemical variables in coastal waters. EcoDOM research is highly relevant to the European Union policy making and research initiatives for increased understanding and modelling of climate-related biogeochemical cycles in European wetland ecosystems and sustainable management of EU’s coastal natural resources. The HCMR Institute of Inland Waters is committed to absorb the research initiated in the proposed project by offering job stability through long-term research scientist appointments to Dr Tzortziou with the conclusion of the project.;100000;100000;FP7-PEOPLE-2007-4-3-IRG;/MC-IRG;HELLENIC CENTRE FOR MARINE RESEARCH;EL;;;"/SCI;/COO";1;0;0;1;0;0 89165;228144;INVISIBLE;ONG;FP7-IDEAS-ERC;ERC-AG-PE8;FP7;Advanced Amorphous Multicomponent Oxides for Transparent Electronics;2009-01-01;2014-12-31;;Imagine having a fully transparent and flexible, foldable, low cost, displays or at the glass window of your home/office, a transparent electronic circuit, do you believe on that? Maybe you are asking me if I am writing science fiction. No I am not. In fact this is a very ambitious objective but is tangible in the framework of this project due to the already acquired experience in the development of transparent thin film transistors using novel multifunctional and multicomponent oxides that can behave as active or passive semiconductor materials. This is an interdisciplinary research project aiming to develop a new class of transparent electronic components, based on multicomponent passive and active oxide semiconductors (n and p-types), to fabricate the novel generation of full transparent electronic devices and circuits, either using rigid or flexible substrates. The emphasis will be put on developing thin film transistors (n and p-TFTs) and integrated circuits for a broad range of applications (from inverters, C-MOS like devices, ring oscillators, CCDs backplanes for active matrices, biossensor arrays for DNA/RNA/proteins detection), boosting to its maximum their electronic performances for next generation of invisible circuits. By doing so, we are contributing for generating a free real state electronics that is able to add new electronic functionalities onto surfaces, which currently are not used in this manner and that silicon cannot contribute. The multicomponent metal oxide materials to be developed will exhibit (mainly) an amorphous or a nanocomposite structure and will be processed by PVD techniques like rf magnetron sputtering at room temperature, compatible with the use of low cost and flexible substrates (polymers, cellulose paper, among others). These will facilitate a migration away from tradition silicon like fab based batch processing to large area, roll to roll manufacturing technology which will offer significant advantages;2250000;2250000;ERC-2008-AdG;/ERC-AG;FACULDADE DE CIENCIAS E TECNOLOGIADA UNIVERSIDADE NOVA DE LISBOA;PT;;;"/PSE;/MAT;/IND;/CON";1;0;0;1;0;0 89857;229459;WATERWORLDS;ONG;FP7-IDEAS-ERC;ERC-AG-SH2;FP7;Waterworlds: Natural environmental disasters and social resilience in anthropological perspective;2009-01-01;2014-06-30;;"The present times are haunted by a sense of vulnerability in the face of major environmental disasters and global climate change. Whatever course and speed the current changes may accrue, their effects on the human world are already manifest. People suffer from a loss of habitual natural resources, from fear of an increasingly unpredictable nature, and from social disruptions as natural habitats are destroyed. Water is the most vital natural resource; it is the sine qua non of human life, and the idea of the present project is to study local, social responses to environmental disasters related to water. They are the melting of ice in the Arctic and in other glacier areas, the rising of seas that flood islands and coastal communities, and the drying of lands accelerating desertification in large parts of Africa and elsewhere. The ambition is to contribute to a renewed theory of social resilience that builds on the actualities of social life in distinct localities, and on human agency as the basis for people s quest for certainty. The proposed research is groundbreaking empirically as well as theoretically. Empirically it contributes a substantial ethnographic supplement to the sweeping diagnoses of the global malaises captured in notions like global warming . Theoretically, the project will allow for a new, general understanding of the effects of environmental disaster on social life, and of the responsibility that people take locally to ensure the survival of their community. New concepts will be developed to facilitate interdisciplinary research and worldwide dialogue. The larger vision is to rethink the human implications of climate change in the wider world, including Europe, by way of an explication of what is and what can be done on the ground. Technologies are useful, but the human and social potential is vital in long-term adaptation to new environmental realities. Frontier research as proposed here will show how.";2979882;2979882;ERC-2008-AdG;/ERC-AG;KOBENHAVNS UNIVERSITET;DK;;;/SOC;1;0;0;1;0;0 90057;220545;MESO-IMPLANT;ONG;FP7-PEOPLE;PEOPLE-2007-2-1.IEF;FP7;Nanostructured Mesoporous Coatings of Implant Materials for Improved Bone Formation;2008-12-01;2010-11-30;;The MESO-IMPLANT project was inspired by the most recent achievements in nanotechnology and regenerative medicine and has two major objectives. The first one is based on the original idea of using the thin films of ordered mesoporous materials as coatings for bone implants. Such coatings have extremely high specific surface areas and pore volumes and are aimed to significantly improve the speed of bone formation on their surface. This would allow to lower the implant fixation time and to lower the probability of implant failure. The applicant will synthesize ordered mesoporous thin films of various metal oxides (eg. titania, alumina) and test how they can improve bone formation. The latter will be performed by direct contact of such layers with bone forming cells (osteoblasts) and observation of their bone forming activity (eg. under optical microscope). Additionally, the mesopore system will be functionalized with bioactive molecules which can mediate osteoblast adhesion process as well as to control the differentiation of the adult stem cells. Successful results of this project may open new research areas both in academia and in industry. The second aim of this project is to give the high-end interdisciplinary training-through-research in nanobiotechnology and nanomedice to the applicant. His background is chemistry and nanomaterials and through this project he will have an unrivalled opportunity to develop his skills in bionanotechnology with help of the leading scientists in the filed. Moreover, he will have a chance to work in the highly multidisciplinary environment at one of the top universities in the world.;168823,92;168823,92;FP7-PEOPLE-2007-2-1-IEF;/MC-IEF;IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE;UK;;;"/SCI;/EDU";1;0;0;1;0;0 90550;235931;BRIDGSEISMTIME;ONG;FP7-PEOPLE;FP7-PEOPLE-IIF-2008;FP7;BRIDGING THE TIMESCALES IN FAULT-SLIP ACCUMULATION: FROM THE EARTHQUAKE RECORD TO THE GEOLOGICAL RECORD;2009-03-16;2011-03-15;;"Natural hazards, earthquakes in particular, can have a significant impact on the economic vitality of European regions. An improved understanding of seismic risk can help minimize the loss of human life and resources during extreme seismic events. This proposal aims to investigate the development of faults in the Earth’s crust and to improve the current understanding of earthquake behavior on timescales ranging from individual earthquakes to millions of years. Faults are breaks in the Earth's crust that grow due to slip caused by earthquakes. However, the slip accumulation on faults during successive earthquakes and the patterns arising from this process are poorly understood, mainly due to the brevity of the available earthquake record. The proposed research will employ an interdisciplinary approach that combines geological and geophysical data, geostatistical tools and numerical models to improve our understanding of earthquake occurrence on faults. The major axes of this approach will involve the acquisition, geostatistical analysis and simulation of fault-slip measured from seismic catalogues, paleoearthquake investigations and surface/subsurface geology. Collectively, the data will span timescales of days to millions of years. The objectives will be accomplished by analyzing and combing the statistics of 1792 slip/time measurements from a global dataset of faults located in 6 fault systems. The dataset will be augmented by new field measurements collected from faults in New Zealand using fault-trenching and outcrop geology. Geostatistical analysis of the fault-slip histories will be performed independently for different timescale-data in order to measure their individual earthquake statistical properties. The results will be subsequently merged using Bayesian statistics into a single stochastic model which will simulate slip histories over a range of timescales. The simulated earthquake statistics will then be tested against real world fault-displacement data.";;202162,99;FP7-PEOPLE-IIF-2008;/MC-IIF;POLYTECHNEIO KRITIS;EL;;;"/SCI;/EMP";1;0;0;1;0;0 90541;237068;MICRONMRLAB;ONG;FP7-PEOPLE;FP7-PEOPLE-IIF-2008;FP7;Rotating Micro-Detectors for Ultra-Sensitive and High-Resolution Analysis of Heterogeneous Matter with Magnetic Resonance: instrumentation, methodology and applications;2009-07-01;2011-06-30;;Nuclear magnetic resonance technology is omnipresent in modern analytical science and biomedicine because of the detailed information it can provide both as a non-invasive imaging as well as a broadband spectroscopic tool. Three-dimensional molecular structure and dynamics and localized functional tomography are possible provided that the sample size is large enough for the technique to be sensitive. This project aims at further developing the recently introduced concept of rotating micro-detectors in order to achieve unprecedented high-resolution and ultra-high sensitivity for the study of amorphous and heterogeneous materials. Miniaturizing the detector size offers higher sensitivity and improved spin dynamics manipulation. Coupling this to a wireless transmission technique allows for experiments on rapidly spinning micro-samples and high-resolution spectroscopy. For the first time nanolitre volume samples become accessible and this opens many avenues for research and development in the field. The host group at the CEA has patented this technology and hopes that with the help of a world class expert in solid-state NMR of glasses we can further develop it and make it transferable to the majority of the magnetic resonance community. Additionally, the candidate will profit and acquire a maturity and scientific independence by the end of this interdisciplinary two-year project encompassing areas chemistry, physics and engineering.;;166011,55;FP7-PEOPLE-IIF-2008;/MC-IIF;COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES;FR;;;"/SCI;/EMP";1;0;0;1;0;0 90013;228684;RE.WEB.I.S.;ONG;FP7-PEOPLE;FP7-2008-PEOPLE-NIGHT;FP7;Researchers' Web In Society;2008-06-01;2008-12-31;;The National and Kapodistrian University of Athens in collaboration with the Hellenic Oceanographers’ Association and the Mediterranean Information Office for Environment, Culture and Sustainable Development aim to undertake ‘Researchers’ Night 2008’, the network trying to raise researchers’ public recognition on Friday 26th September 2008 across Europe. Thus, the consortium intends to hold an outdoor event called ‘Researchers’ Web In Society’ (Re.Web.I.S.) in one of the most central locations of Athens, on Propylaia Square. ‘Re.Web.I.S.’ will be presented in the form of an interdisciplinary ‘web’ woven by the three partners where scientists of biology, chemistry, geology and physics will try to communicate to the public their work in relation to the natural world, as well as their involvement in the climate change and greenhouse effect research. The researchers will try to raise the alarm concerning the new global changes in a comprehensible, lay yet scientific, and at the same time festive way highlighting that science is the means for the achievement of a better life and future. On the entertainment aspect, there will be three-dimensional simulations to give attendees the chance to experience certain phenomena, light-hearted games and performances. Therefore, ‘Re.Web.I.S.’ hopes to constitute a central massive event addressing audiences of all age categories, backgrounds and interests mingling them with researchers, giving them the chance to interact with scientists in a relaxed atmosphere.;60580;60580;FP7-PEOPLE-NIGHT-2008;/CSA-SA;ETHNIKO KAI KAPODISTRIAKO PANEPISTIMIO ATHINON;EL;"MEDITERRANEAN INFORMATION OFFICE for Environment, Culture and Sustainable Development;HELLENIC OCEANOGRAPHERS ASSOCIATION";EL;"/SCI;/SOC";1;0;0;1;0;0 90505;229135;NAFU;ONG;FP7-IDEAS-ERC;ERC-AG-SH5;FP7;Narrating Futures;2009-04-01;2012-03-31;;"This project is unique as it identifies a totally new field within Narratology: multiple future narratives. Narratives are traditionally concerned with past events. Even if they claim to be about the future (e.g., utopian tales), narratives treat these events as if they had already happened. In contrast, future narratives in our sense are narratives that preserve the characteristic feature of future time, viz. that it is open, multiple, not yet crystallized into actuality. We do not yet have a grammar, a logic, or a poetics of future(s) narratives. This project promises to offer these. Firmly rooted in Narratology, the project has interesting interfaces with Philosophy, Linguistics, the theory of History, Game Theory, Decision Theory, and Futurology. It will analyze a corpus of future-related 'texts' and conceptualize them so that the narrative mediation of complex multiple futures' scenarios becomes feasible. The impact of the findings of this trailblazing Humanities project will be across the board not only for the Humanities and Social Sciences, but also for Political, Environmental, and Business decision making, since future scenarios that retain the openness of forked-path or feedback or cross-impact models can only be communicated if they rely on multiple-narrative techniques and devices. 'Narrative' here refers not only to fictional, but also to non-fictional narratives; likewise, the narratives in question are by no means restricted to any one medium, such as language, or print. Movies, computer games etc. are equally in the focus of our research. Necessarily interdisciplinary, it is, however, an incontestably narratological project, because Narratology provides the central paradigm for this new field of enquiry, 'narrative'. To sum up: There is of now no division in the Humanities that would systematically investigate these phenomena. This field is constituted by this identification. This proposal opens up a totally new research area.";899464;899464;ERC-2008-AdG;/ERC-AG;LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN;DE;;;/SOC;1;0;0;1;0;0 90468;239162;ISOMETRIC;ONG;FP7-PEOPLE;PEOPLE-2007-2-2.ERG;FP7;Isometric actions;2009-04-01;2012-03-31;;"The increasingly demanding challenges in our society require the development of innovative ideas. These ideas often originate from mathematical models of phenomena in natural and life sciences, in medicine and business, in technology and engineering, in manufacturing and design, and in other areas. Many of these models lead to geometric structures describing the phenomena precisely or, in most cases, approximately. Innovation and scientific development depends upon a thorough understanding of these geometric structures. The aim of this project is to investigate geometric structures from the viewpoint of their symmetries, and to characterize them by some distinguished features. We are interested in the geometry of those submanifolds that arise as orbits of isometric actions on Riemannian manifolds. More precisely, we plan to investigate the following problems: - Classification of isometric actions on Riemannian manifolds. We will focus on polar and hyperpolar actions, or cohomogeneity one actions, that have attracted much attention over the last few years. - Study of the geometry of the orbits of isometric actions on Riemannian manifolds. - Characterization of the orbits of isometric actions by means of their geometric properties. The objectives of this proposal will be achieved by using techniques recently developed by the applicant and his previous host group and by developing a computer program of symbolic calculus, a matter in which the applicant is experienced. This proposal suits the objectives of the action: it promotes interdisciplinary relations (isometric actions have successfully been used for the construction and investigation of special structures which have substantial interest in physics; we use programming techniques to handle symbolic calculations), reinforces international relations and provides the applicant with the chance of a lasting professional integration in a research institution.";45000;45000;FP7-PEOPLE-ERG-2008;/MC-ERG;UNIVERSIDAD DE SANTIAGO DE COMPOSTELA;ES;;;"/SCI;/EDU";1;0;0;1;0;0 88270;212919;PRINS;ONG;FP7-INFRASTRUCTURES;INFRA-2007-2.2-01;FP7;Pan-European Reseach Infrastructure for Nano-Structures;2008-04-01;2010-03-31;;The project focuses on all needed preparatory actions to enable in the following phase the construction of a Research Infrastructure (RI) called Pan-European Research Infrastructure for Nano-Structures (PRINS), with the aim of enabling European innovative research for the ultimate scaling of electronics component and circuits. The platform will be truly interdisciplinary by allowing the convergence of “top-down” technology, which is today the main enabler of Moore’s law (i.e. transistor scaling), with “bottom-up” methods derived from fundamental disciplines such as material physics, chemistry, biotechnology and particle electronics. The open access of this infrastructure provided to the Scientific Community will enable the cross-disciplinary fertilization of academic and industrial competences in the areas of nanoelectronics, nanosystems, nanobiology, nanophotonics, etc. The consortium consists of European leading Research Centres, industrial partners and Public Authorities and Funding Agencies. Key activities include 1) setting up a legal framework for the operation of the RI, 2) defining the required management structures for the daily operation of the RI, for screening and evaluating the incoming access requests, and for technical and financial aspects related to the strategy of the RI and its long term sustainability, including the role of the different stakeholders and possible funding schemes, 3) defining the legal and practical issues related to the different operation modes for giving access ad hosting researchers, and 4) defining the timeline of the RI, its different areas, and its associated business plan (operational costs, resources, funding possibilities, costs for giving access, etc).;1389138,5;1000000;FP7-INFRASTRUCTURES-2007-1;/CP-CSA-Infra;INTERUNIVERSITAIR MICRO-ELECTRONICA CENTRUM;BE;"ASML NETHERLANDS B.V.;STMICROELECTRONICS CROLLES 2 SAS;FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.;COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES;INFINEON TECHNOLOGIES AG;NXP SEMICONDUCTORS NETHERLANDS BV;VLAAMS GEWEST";"NL;FR;DE;BE";/SCI;1;0;0;1;0;0 87546;200911;GAMMARAYBINARIES;ONG;FP7-IDEAS-ERC;ERC-SG-PE7;FP7;Exploring the gamma-ray sky: binaries, microquasars and their impact on understanding particle acceleration, relativistic winds and accretion/ejection phenomena in cosmic sources;2008-07-01;2013-06-30;;The most energetic photons in the universe are produced by poorly known processes, typically in the vicinity of neutron stars or black holes. The past couple of years have seen an increase in the number of known sources of very high energy gamma-ray radiation from a handful to almost 50, thanks to the European collaborations HESS and MAGIC. Many of those sources are pulsar wind nebulae, supernova remnants or active galactic nuclei. HESS and MAGIC have also discovered gamma-ray emission from binary systems, finding that some emit most of their radiation at the highest energies. Expectations are running high with the December launch of the GLAST space telescope which will provide daily all-sky information in high energy gamma-rays with a sensitivity comparable to that achieved in years by its predecessor. I propose to explore the exciting observational opportunities in high energy gamma-ray astronomy with an emphasis on non-thermal emission from compact binary sources. Binary systems are intriguing new laboratories to understand how particle acceleration works in cosmic sources. The physics of gamma-ray emitting binary systems is related to that in pulsar wind nebulae or in active galactic nuclei. High energy gamma-ray emission is the result of non-thermal, out-of-equilibrium processes that challenge our intuitions built upon everyday phenomena. The particles are billions of times more energetic than X-rays and can reach energies greater than those in particle accelerators. Binary systems offer a novel, constrained environment to study how the cosmic rays that pervade our Galaxy are accelerated and how non-thermal emission is related to the formation of relativistic jets from black holes (accretion/ejection). The study requires a combination of skills in multiwavelength observations, interdisciplinary experience with gamma-ray observational techniques originating from particle physics, and theoretical know-how in accretion and high energy phenomena.;794752;794752;ERC-2007-StG;/ERC-SG;UNIVERSITE JOSEPH FOURIER GRENOBLE 1;FR;;;"/PSE;/AER;/SPA";1;0;0;1;0;0 89810;202674;EU-LIMITS;ONG;FP7-PEOPLE;PEOPLE-2007-2-2.ERG;FP7;The scope of EU law;2007-09-01;2010-08-31;;'The present research project is focused on the limits and scope of the legal order of the European Union through a detailed examination of the personal and material scopes of application of Treaty provisions (for example, the free movement rules or the provisions on citizenship of the Union), the extent of the competences of the Union (for example, the limits of Articles 95 EC, on internal market legislation, or of Article 308 EC, on implied powers), and the institutional framework in charge of the definition and enforcement of those limits (the relative merits and demerits of the Court of Justice, the Council, the European Parliament, the Commission and national institutions to trace the limits of EU law). The proposed research will also examine important issues such as the scope of fundamental rights protection in EU law, the borders between EU law and EC law, and the notion of 'economic activity', which defines the scope of application of many important Treaty provisions. The project is interdisciplinary, taking into account the law, political science and theories of institutional choice. It will hopefully result in an analytic framework to examine this kind of issues and also in more practical recommendations from a normative and institutional point of view.';45000;45000;FP7-PEOPLE-2007-2-2-ERG;/MC-ERG;CENTRO DE ESTUDIOS POLITICOS Y CONS TITUCIONALES;ES;;;"/SCI;/EDU";1;0;0;1;0;0 191236;617700;EXPECT HEAL-TH;ONG;FP7-IDEAS-ERC;ERC-CG-2013-SH4;FP7;Empowering expectations for health and disease: training the immune and endocrine system;2014-09-01;2019-08-31;;"Expectations about health and disease induce immune and endocrine responses and directly affect health and treatment outcomes. However, there is an urge to understand the mechanical underpinnings how expectations affect immune and endocrine responses and how this knowledge can be used for therapeutic interventions. My research group studies the main expectancy learning mechanisms for itch and pain as a generic expectancy model across symptoms and conditions. We recently showed that dual expectancy learning processes (i.e. conditioning and suggestions) are most powerful for itch symptoms, corresponding with findings for other symptoms and conditions. Based on these studies, I propose a groundbreaking dual expectancy learning approach, testing whether combined expectancy learning processes (i.e. both conditioning and suggestions, offered with personalized cues and exposure to relevant stressors) affect most profoundly the immune and endocrine system, in turn affecting health and disease outcomes. The major aim is to unravel the central mechanisms of how peoples’ expectations affect immune and endocrine responses and related health outcomes, through the use of pioneering multidisciplinary methods in healthy and clinical populations. First, we systematically train immune and endocrine responses and relate them to psychological, neurobiological and genetic mechanisms. Second, we test these manipulations for physical health challenges (e.g. inflammatory or allergic histamine reactions) in healthy subjects and patients. Third, we study the long-term effects in chronic inflammatory itch and pain conditions (e.g. replacing anti-inflammatory pharmacotherapies, reducing side effects). This interdisciplinary, cross-boundary project progresses key theoretical knowledge of the central expectation mechanisms for immune and endocrine responses. Findings open new horizons for health prevention and therapeutic interventions for various inflammatory conditions and physical symptoms.";1981009;1981009;ERC-2013-CoG;/ERC-CG;UNIVERSITEIT LEIDEN;NL;;;"/LIF;/SCI";1;0;0;1;0;0 88383;200443;COST II;ONG;FP7-GA;COST;FP7;Provision of Scientific, Technical and Administrative Management of COST;2007-06-02;2015-01-01;;"This EC-ESF COST II Grant Agreement is meant to provide support to COST over the duration of the 7th Framework Programme, i.e. at least 91 months in total, as defined in the Specific Programme “Cooperation”. It is implemented through an initial period from 2 June 2007 to 1 June 2008 followed by yearly amendments to cover the whole duration of FP7. COST is a unique means for European researchers to jointly develop their own ideas and new initiatives across all scientific disciplines through trans-European networking of nationally funded research activities. Based on a European intergovernmental framework for cooperation in science and technology, COST has contributed since its creation 40 years ago to closing the gap between science, policy makers and society throughout Europe and beyond. COST's mission is to enable, through a “bottom-up” approach open to all science and technology domains including interdisciplinary, new and emergent fields, break-through scientific developments leading to new concepts and products and thereby contribute to strengthen Europe’s research and innovation capacities. COST, as an integral part of the ERA, is putting particular efforts in rein-forcing its activities and impact in European countries where excellent researchers need to gain visibility at European and global level by con-necting them throughout Europe, building trust, and contributing to strengthen their capacities. COST is governed by the COST Committee of Senior Officials (CSO), which is composed of representatives of 35 COST Member Countries (plus one cooperating state) and elects its President for a renewable mandate of three years. COST is financed by the EU through a budget from the Framework Pro-grammes for research, technological development and demonstration activities and has been implemented since 2003 by the European Science Foundation (ESF) as implementing agent through a Grant Agreement signed with the European Commission. The ESF supports COST in the execution of its activities through the COST Office, guaranteeing professional management. The COST Office is exclusively dedicated to the implementation of the CSO decisions by ensuring the scientific and technical management of COST networking, strategic and other activities; it provides support to the COST CSO on a continuous basis. Under the 7th Framework Programme (FP7) the “COST II Grant Agree-ment” entered into force on 2 June 2007 and is amended yearly. The amendments 2008, 2009, 2010, 2011 and 2012 included revisions of work packages in the original Grant Agreement with the aim of updating them through optimising efficiency, increasing quality assurance, further focusing the science and technology networking activities and enhancing scientific and technological inter-disciplinarity as well as through promot-ing outreach activities to raise public awareness on COST. Following the successful Mid-Term Evaluation report in 2010, the funding has increased up to 250 Mio.";280086352,1;250000000;FP7-2007-COST;/CSA-SA;FONDATION EUROPEENNE DE LA SCIENCE;FR;;;/ECO;1;0;0;1;0;0 88231;218265;INEX;ONG;FP7-SECURITY;SEC-2007-6.5-02;FP7;Converging and conflicting ethical values in the internal/external security continuum in Europe;2008-04-01;2011-03-31;http://www.inexproject.eu/;Security and insecurity are social, cultural, political concepts. Nowhere is this more evident than in the challenges produced by the evolving continuum between internal and external security challenges. The interdisciplinary project INEX is designed around two research axes: thematic and geopolitical. On the thematic axis it will study four fields of knowledge of high relevance to the question of the ethics and the value-laden tensions arising along the continuum between internal and external security in Europe: (1) the ethical consequences of the proliferation of security technologies, (2) the legal dilemmas that arise from transnational security arrangements, (3) the ethical and value questions that stem from the shifting role of security professionals and (4) the consequences of the changing role of foreign security policy in an era when the distinction between the external and internal borders grows less distinct On the geopolitical axis it will study and produce recommendations relative to two geographical theatres of high relevance for ethical issues of internal/external security: the Eastern European ‘neighbourhood’ including Belarus, Ukraine, Moldova and the Mediterranean ‘neighbourhood’ including Morocco, Algeria and Egypt. The project will link directly with representatives of the security technology industry as well as security provision services that implement concretely to the border security arrangements. The state-of-the-art research carried out by the project will result in a variety of different outputs aimed primarily at relevant policy-makers, researchers and educators. It will present analyses of current security challenges with particular attention to the human side of the security challenge, and on this basis propose remedial to the new challenges of the internal/external security continuum.;2422082;1890248;FP7-SEC-2007-1;/CP;INSTITUTT FOR FREDSFORSKNING STIFTELSE;NO;"CENTRE FOR EUROPEAN POLICY STUDIES;VRIJE UNIVERSITEIT BRUSSEL;Centre d’Etudes sur les Conflits;COLLEGIUM CIVITAS;VERENIGING VOOR CHRISTELIJK HOGER ONDERWIJS WETENSCHAPPELIJK ONDERZOEK EN PATIENTENZORG;Ericsson AS;Bilkent Üniversitesi;Centre for International Information and Documentation in Barcelona";"BE;FR;PL;NL;NO;TR;ES";"/ETH;/SEC";1;0;0;1;0;0 88106;220207;HICSCERN;ONG;FP7-PEOPLE;PEOPLE-2007-2-1.IEF;FP7;Heavy Ion Collisions and Strings at CERN;2008-10-01;2010-09-30;;The present project aims at studying the fundamental properties of matter close to the deconfinement phase transition of QCD. To do so, we explore a new theoretical development, the AdS/CFT correspondence, which allows us to study the physics of strongly coupled plasmas by string theory techniques. With this new tool, we shall address the propagation of probes in strongly coupled matter, as well as the back-reaction of that matter to the passage of probes. These studies will lead us to propose new strategies for analyzing and interpreting experimental data taken in heavy ion collisions at the CERN Large Hadron Collider. The project deals with the newly emerging interdisciplinary interplay of heavy ion phenomenology, string theory and experimental high energy nuclear physics. It is also a means for knowledge transfer between the heavy ion physics and string theory communities and it has the potential to contribute to academic training and education. The training proposed in this project aims at growing all aspects of the applicant's capability to perform leading independent research.;173400,82;173400,82;FP7-PEOPLE-2007-2-1-IEF;/MC-IEF;EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH;CH;;;"/SCI;/EDU";1;0;0;1;0;0 87942;206080;DEHALORES;ONG;FP7-IDEAS-ERC;ERC-SG-LS1;FP7;Breathing chlorinated compounds: unravelling the biochemistry underpinning (de)halorespiration, an exciting bacterial metabolism with significant bioremediation potential;2008-09-01;2013-08-31;;Bacterial dehalorespiration is a microbial respiratory process in which halogenated hydrocarbons, from natural or anthropogenic origin, act as terminal electron acceptors. This leads to effective dehalogenation of these compounds, and as such their degradation and detoxification. The bacterial species, their enzymes and other components responsible for this unusual metabolism have only recently been identified. Unlocking the full potential of this process for bioremediation of persistent organohalides, such as polychlorinated biphenyls (PCBs) and tetrachloroethene, requires detailed understanding of the underpinning biochemistry. However, the regulation, mechanism and structure of the reductive dehalogenase (the enzyme responsible for delivering electrons to the halogenated substrates) are poorly understood. This ambitious proposal seeks to study representatives of the distinct reductive dehalogenase classes as well as key elements of the associated regulatory systems. Our group has been at the forefront of studying the biochemistry underpinning transcriptional regulation of dehalorespiration, providing detailed insights in the protein CprK at the atomic level. However, it is now apparent that only a subset of dehalogenases are regulated by CprK homologues with little known about the other regulators. In addition, studies on the reductive dehalogenases have been hampered by the inability to purify sufficient quantities. Using an interdisciplinary, biophysical approach focused around X-ray crystallography, enzymology and molecular biology, combined with novel reductive dehalogenase production methods, we aim to provide a detailed understanding and identification of the structural elements crucial to reductive dehalogenase mechanism and regulation. At the same time, we aim to apply the knowledge gathered and study the feasibility of generating improved dehalorespiratory components for biosensing or bioremediation applications through laboratory assisted evolution.;1148522;1148522;ERC-2007-StG;/ERC-SG;THE UNIVERSITY OF MANCHESTER;UK;;;"/BIO;/LIF";1;0;0;1;0;0 88561;205119;R-EVOLUTION-M-R;ONG;FP7-IDEAS-ERC;ERC-SG-PE6;FP7;Magnetic Resonance of Heterogeneous Matter in Rotating Magnetic Fields: Applications to Living Systems;2008-11-01;2014-10-31;;The goal of this project is to establish the foundations for the next generation diagnostic magnetic resonance for in-vivo studies of biochemical processes. Magnetic resonance, unlike other techniques, probes in a non-invasive manner the local structure and dynamics of chemical and biological function. Many systems (e.g. organisms) are however heterogeneous and, currently, studies by high-resolution NMR spectroscopy necessitate fast sample rotation (thousands of revolutions per second) at the so-called “magic angle” with the magnetic field. Practical, scientific and ethical issues are raised when we extrapolate this technique to small animals or even to living cell cultures.We aim to push the technology of magnetic resonance to the next level by introducing rotating magnetic fields around static samples. Rotating magnets capable of offering ultra high-resolution NMR and MRI will be built and used to acquire metabolic signatures from living organisms at cellular and macroscopic level of observation. This interdisciplinary project aims at developing frontier concepts in magnetic resonance and gathering state-of-the-art approaches in the areas of bioengineering, magnetism, magnetic resonance microscopy and spectroscopy to place them at the service of medicine and biochemistry.Our strategy consists of forming a new, independent and perennial research team, of 3 researchers, 1 technician, 2 post-docs and 2 PhDs. The concept, fabrication and evaluation of a prototype magnet will occur within the first three years, and applications to cell cultures and small animals are envisaged until the end of the 5 years. Spectroscopic MRI in rotating fields has never been investigated and will produce new methodological and instrumentation advances. The outcome will be groundbreaking since for the first time localized metabolism will be studied in living organisms. This research will therefore open new avenues to non-invasive monitoring biomedical tools for diagnosis and prevention.;1828564;1827564;ERC-2007-StG;/ERC-SG;COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES;FR;ECOLE NORMALE SUPERIEURE;FR;"/PSE;/IPS";1;0;0;1;0;0 87592;221716;CGI-FOR-FILM;ONG;FP7-PEOPLE;PEOPLE-2007-4-1.IOF;FP7;Controllable global illumination for film production;2008-08-01;2011-07-31;;The ultimate objective of the project is to start a new interdisciplinary computer graphics research group in the return host under the direction of the fellow. This leading position will allow him to fully exploit the skills acquired during the outgoing stage at the renowned Cornell University Program of Computer Graphics, and will be the foundation of his long-term independent research career. The central source of the new skills will be the execution of the proposed research, where our goal is to allow the artists in film production to create more compelling realistic computer-generated imagery through establishing global illumination as a common tool for image rendering. To reach this goal, we propose several novel scientific aspects, the most significant being the study of visual importance of various distance components of light transport on the perceived quality of synthetic images. Results of this study will drive the design choices in our development of new algorithms and data structures, such as: a) new illumination caching strategies for efficient global illumination computation in scenes with complex geometry and materials, b) memory-efficient representation of the light transport operator for real-time relighting in cinematic lighting design. In addition, a novel interface will be developed to provide artistic control over global illumination computation. The proposed research, encompassing several disciplines, such as psychophysics and cognitive sciences, statistical data modeling, and human-computer interaction, is designed specifically to deepen and widen fellow’s expertise and add to his multidisciplinary skills.;202676,7;202676,7;FP7-PEOPLE-2007-4-1-IOF;/MC-IOF;UNIVERZITA KARLOVA;CZ;;;"/SCI;/COO";1;0;0;1;0;0 95413;253911;ASTRA;ONG;FP7-PEOPLE;FP7-PEOPLE-2009-IEF;FP7;Argumentation Strategies;2010-04-01;2011-08-31;;Important aspects of everyday life (e.g. healthcare, commerce, law) increasingly rely on networks of distributed but co-operating computer systems. An understanding of negotiation, joint decision making and control of private information in such systems has therefore become a key challenge for computer science. My work will address this challenge by creating a theoretical foundation with which systems with conflicting information, goals and assumptions can jointly decide how to act by exchanging arguments (e.g. when one system provides sound reasons for another to grant access to private information). Whilst work to date has focussed on protocols that restrict the various communicative acts that can be made during such argumentation-based interactions, what is lacking is an investigation into how the choice of which act to make affects the outcome of the interaction. The proposed work will address this shortcoming by developing the first formally validated set of strategies to allow selection of communicative acts to make in order to influence a joint decision about how to act. This will establish a groundbreaking methodology for the intelligent design of argumentation-based interaction strategies. The significant results expected will consolidate my growing reputation as a leading researcher in the field of computational argumentation. As a result of the proposed mobility, I will considerably develop my academic network, establish new interdisciplinary collaborations, develop necessary research skills and gain experience in a variety of research areas. This fellowship will allow me to develop my personal research agenda and will stand me in the ideal position to go on to have an internationally successful independent research career. At the end of the fellowship I will be competitively placed to acquire a permanent academic post at a leading European university and will be in a position to apply for funding with which I can start to build up my own research group.;153548,8;153548,8;FP7-PEOPLE-2009-IEF;/MC-IEF;UNIVERSITEIT UTRECHT;NL;;;"/SCI;/EDU;/ITT";1;0;0;1;0;0 87454;204398;FINGOVEU;ONG;FP7-IDEAS-ERC;ERC-SG-SH2;FP7;Financial Services Governance in the European Union;2008-10-01;2012-03-31;;"This project examines the governance of financial services in the European Union (EU). This research is both academically interesting and policy relevant. Academic research has not kept pace with new developments in this field, and interdisciplinary research is very much needed, as financial services governance is at the cross road between politics, economics and law. At the practical level, the financial sector is a core part of national economies and one of the most active areas of EU policy making. Moreover, this research will contribute to informing the public discussion in a policy area that is often perceived as 'technical', which tends to limit the public scrutiny of it. For the purposes of this research, the governance of financial services in the EU includes: i) the institutional framework through which policies are made; ii) regulation, which is comprised of market-making and market-framing measures; and iii) supervision, that is: the monitoring and enforcement of regulation as well as the practical cooperation between supervisory authorities. First, the project will map the complex institutional framework underpinning financial services governance in the EU, explaining how such framework interplays with regulatory and supervisory arrangements in international arenas and in selected countries. Second, through competitive hypotheses testing, the project will analyse the EU policy-making processes in the financial sector: the main policy-makers and stakeholders involved; their resources, relationships and influence on the policy process; and the outcome. Besides contributing to the policy-oriented debate on financial services regulation and supervision in the EU, the ultimate theoretical goal of the research is to devise an integrated analytical framework that by combining various theoretical approaches and identifying their scope conditions could account for financial services governance in the EU, advancing theories of EU policy making.";377464;377464;ERC-2007-StG;/ERC-SG;THE UNIVERSITY OF SUSSEX;UK;;;/SOC;1;0;0;1;0;0 87447;203479;QUPOL;ONG;FP7-IDEAS-ERC;ERC-SG-PE2;FP7;Quantum gases of ultracold polar molecules;2008-08-01;2013-07-31;;I propose to realize quantum gases of ultracold molecules with a permanent electric dipole moment. This project aims at a significant extension of the field of ultracold quantum gases towards more complex particles interacting via long-range, anisotropic interactions. Quantum gases of polar molecules would allow to study novel kinds of matter waves, to solve open questions in modern condensed matter physics, to explore novel quantum phases and to implement novel quantum computing schemes. Weakly bound heteronuclear dimers formed in ultracold atomic quantum mixtures via magnetic Feshbach resonances will be coherently transferred to deeply-bound ro-vibrational states using laser fields. The formation of both bosonic and fermionic molecules will be explored in different alkali mixtures. The high degree of coherence of the molecular quantum gases will allow to prepare them in selected rotational states of the absolute ground electronic and vibrational state. The molecular electric dipoles will be manipulated via electric and microwave fields. The precise dynamical control of the shape and strength of the dipole-dipole potential will allow to engineer a variety of quantum states and to study many interdisciplinary phenomena. The following themes will be explored: phenomenology of dipolar quantum gases, lattice spin models, polar molecules as qubits.;1230000;1230000;ERC-2007-StG;/ERC-SG;LABORATORIO EUROPEO DI SPETTROSCOPIE NON LINEARI;IT;;;"/PSE;/SCI";1;0;0;1;0;0 88124;209234;SPIN;ONG;FP7-IDEAS-ERC;ERC-SG-SH3;FP7;Natural speech comprehension: Comprehension of speech in noise;2008-10-01;2013-09-30;;The SpiN project stands at the frontier between experimental linguistics and cognitive neuroscience research. It aims at achieving a critical break-through in the domain of speech-in-noise comprehension by setting up a dedicated interdisciplinary research team. The comprehension of speech in noise is a complex task even for normal hearing people and it is the primary and principal problem experienced by people facing hearing loss or auditory processing disorders. Under ecological conditions, a speech signal scarcely ever reaches the ear without any interfering noise. We will study our capacity to understand speech by relying on the interaction between auditory processing and the specialized cognitive processes involved in speech comprehension and degraded speech restoration. The originality of our approach is to investigate natural speech comprehension both from a language-based and an auditory-driven perspective, using the same synergy as is brought into play when those systems work to achieve speech comprehension. To this end, several experimental techniques including behavioural assessment, electrophysiological measurements and neuroimaging will be used to conduct tests in different target populations (normal hearing participants, hearing impaired and speech processing impaired patients). A systematic evaluation of auditory performances will be done and compared to results of all experiments carried out. In all the results we will highlight the inter-individual variability observed in speech comprehension performances. This will allow us to unravel the links between sensory processes and speech intelligibility and obtain valuable information for the understanding of the neurocognitive processes underlying the comprehension of speech in general. Understanding speech restoration in ecological situations constitutes a challenge that scientists are bound to face as it is becoming such an important societal issue given the omnipresence of noise in modern societies.;600000;600000;ERC-2007-StG;/ERC-SG;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FR;;;/SOC;1;0;0;1;0;0 192779;237528;MIELT1D;ONG;FP7-PEOPLE;FP7-PEOPLE-IIF-2008;FP7;MHC Class I Expression Level in Type 1 Diabetes;2009-03-02;2009-10-01;;Type 1 diabetes (T1D) results from autoimmune attack of the insulin-producing beta cells, and consequently glucose can no longer be absorbed and utilized by the body. Although patients receive insulin injections to help regulate blood glucose, the regulation achieved is far from ideal and patients develop long-term complications. Current strategies to prevent T1D involve developing immunomodulatory therapies to arrest or slow disease progression of the autoimmune process. It is likely such immunomodulatory therapies will have an increased chance of success if delivered prior to the development of autoimmunity. Therefore, understanding the genetic basis of T1D is very important to the identification of ‘at risk’ individuals prior to the onset an autoimmune response to their islets so that preventative immunotherapies can be developed. MIELT1D aims to understand the role of ß2M/MHC class I in susceptibility to T1D. In particular, MIELT1D aims to understand the selection of diabetogenic CD8 T cell by the ß2M/MHCclass I expression level during thymic development, in order to develop markers for targeting these cells in predisposed individuals. Secondly we propose to test the peripheral blood of patients with T1D to determine whether ß2M expression level is correlated with susceptibility to disease, and whether there are polymorphisms within the promoter of the ß2M gene that may be used as a genetic screen for T1D risk. The multidisciplinary interaction of leading international expertise in the pathology of diabetes and autoimmunity, the Immunology of T cell development in the thymus, and state-of-the-art genetic screening platforms, along with an interdisciplinary approach using inbred diabetes prone animals to probe important molecular questions not possible to address in humans due to the complex genetics, are essential to achieve these aims. MIELT1D will lead to the design of early therapeutical intervention so as to lowering the burden of T1D in Europe.;119208,7;119208,7;FP7-PEOPLE-IIF-2008;/MC-IIF;UNIVERSITE DE LA MEDITERRANEE D'AIX-MARSEILLE II;FR;;;"/SCI;/EMP";1;0;0;1;0;0 87448;203749;QUCO;ONG;FP7-IDEAS-ERC;ERC-SG-PE5;FP7;The power of quantum computers;2008-07-01;2011-11-30;;"Quantum computation has been put forward as a way to overcome current computational limits, by exploiting the quantum properties of nature. It is an interdisciplinary area at the interface of physics and computation. Since Shor's groundbreaking discovery in 1994 that a quantum computer can factor numbers efficiently, strong, steady advances have been made in understanding the advantages of quantum resources and numerous experimental efforts are underway to implement this model of computation. Our research goal is to expand our understanding of quantum resources and computation and its interplay with classical computation, as well as to open new directions. More specifically, we want to advance progress in algorithm design, using new paradigms we have recently helped to develop, and to deepen our understanding of the computational power of physical resources like shared quantum states (entanglement), quantum communication, quantum memory and restricted quantum systems. An important aspect of this proposal is to parallel this investigation into the power of quantum systems with a study of its limits. Specifically we want to identify potential hard problems for quantum computers and to explore their hardness properties as a base for new classical cryptosystems that are secure against quantum adversaries. We also want to deepen our understanding of the effects of an adversary with quantum resources in cryptography. In a society where information is a crucial economic resource it is important to protect today's information against tomorrow's possible progress in the implementation of quantum computers. In this line of research we also propose to explore the systematic use of the emerging toolbox of quantum techniques to find solutions for classical problems with quantum arguments.";744000;744000;ERC-2007-StG;/ERC-SG;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS;FR;TEL AVIV UNIVERSITY;IL;"/PSE;/IPS;/TEL";1;0;0;1;0;0 87656;220104;COMBINE;ONG;FP7-PEOPLE;PEOPLE-2007-2-1.IEF;FP7;COccolithophores Morphology, BIogeography, geNetic and Ecology database;2008-08-18;2010-07-17;;Coccolithophores are unicellular calcifying algae that form a major component of the oceanic phytoplankton. They play a key role in the global carbon cycle as a pump of inorganic carbon to the deep ocean and to the sediment, and are responsible for a considerable part of the ocean/atmosphere exchange of climate relevant gases (CO2, DMS). In the context of global climate change, and especially ocean acidification, understanding the role of plankton in modulating oceanic biogeochemistry has become a critical interdisciplinary research priority, with the need of developing reliable quantitative knowledge of the biogeography and ecology of key groups at oceanic scale. COMBINE specifically aims (a) to develop modern techniques for accurate coccolithophore biodiversity assessment, (b) to apply them within the AMT program to produce a high quality reference database on Atlantic coccolithophore biogeography, (c) to use this database to produce reliable data on the autecology of key species, i.e. their affinities with physico-chemical parameters like temperature and pCO2, and (d) to use/develop a molecular genetic tool (COD-FISH) to investigate the ecology of haploid and diploid phases of the life-cycle of common coccolithophore species. Overall this will both develop our understanding of coccolithophore ecology at species-level and produce a robust quantitative model of their biogeography through the Atlantic, which will help predicting their role as booster/reducer of global warming and ocean acidification. COMBINE will be conducted at the NHM, London where the necessary instrumentation, expertise and AMT samples are available, and will involve the CEREGE, Aix en Provence and the SB, Roscoff for automatic coccolith recognition and coccolithophore genetics expertise. COMBINE will provide unique training to the candidate by developing and applying innovative techniques in cooperation with leading scientists as well as deliver a major contribution to their joint research.;169908,95;169908,95;FP7-PEOPLE-2007-2-1-IEF;/MC-IEF;NATURAL HISTORY MUSEUM;UK;;;"/SCI;/EDU";1;0;0;1;0;0 90896;219394;BIOMIMETIC-CORTEX;ONG;FP7-PEOPLE;PEOPLE-2007-2-1.IEF;FP7;Actin-membrane interaction in biomimetic and living cellular systems studied with a novel, high precision optical method;2009-10-01;2011-03-31;;"The lethal potential of cancer is due to abnormal cell division and aggressive metastatic activity that turn resting cancer cells into motile structures which spread through an organism, resulting in numerous and often uncontrollably growing subpopulations. It is well known that both cell motility and cell division depend crucially on cell mechanics, namely on actin cortex. The actin cortex consists of a dense biopolymer network, steadily contracted by myosin motors. A key to understanding the abnormal motility and proliferation of cancer cells is the investigation and quantification of the physical properties of the actin cortex. Of special interest is the activity of the acto-myosin network and its interaction with the plasma membrane. This actin-membrane interplay is a major contributor to many physical properties of the whole cell. We propose a systematic study of acto-myosin membrane interactions using biomimetic and living cells in combination with a novel optical method that allows simultaneous manipulation and detection of the cell edge with high spatial and temporal resolution. Our main objectives are: a) to quantify the physics of the actin cortex in biomimetic cells; b) to understand the nonequilibrium statistical mechanics of active acto-myosin networks; c) to study of actin-membrane interactions in the cell cortex and the lamellipodium of living cells. The applicant and the host institute provide complementary skills for this project. The applicant has expertise in advanced optical detection methods, cell motility and stochastic processes, and the host institute will provide the biomimetic actin cortex system, expertise on biomimetics, active systems and biology and the interdisciplinary working environment, including biologists and biochemists, necessary for this project. In this respect both the applicant and the host institution will benefit from the fellowship.";171033,9;171033,9;FP7-PEOPLE-2007-2-1-IEF;/MC-IEF;INSTITUT CURIE;FR;;;"/SCI;/EDU";1;0;0;1;0;0 88100;217967;SGL FOR USAR;ONG;FP7-SECURITY;SEC-2007-4.2-02;FP7;Second Generation Locator for Urban Search and Rescue Operations;2008-10-01;2012-10-31;http://www.sgl-eu.org;"The Second Generation Locator for Urban Search and Rescue Operations (SGL for USaR) is mission oriented towards solving critical problems following large scale structural collapses in urban locations. The devotion, courage and expertise of rescuers need to be matched by procedures and technology that will enable safe and effective responses. This Integrated Project will combine chemical and physical sensors integration with the development of an open ICT platform for addressing mobility and time-critical requirements of USaR Operations. The project will also focus on medical issues and on the relevant ethical dilemmas. SGL for USaR has marshaled a pan-European interdisciplinary project team to produce a well-balanced consortium of 21 partners including rescue teams, researchers and SMEs along with the support of 15 LOIs. The project is formed by eight sub-projects (work packages) running in parallel. These WPs address the development of simulation environments; the development and validation of portable devices for location operations; the development and validation of smart sensors environment for monitoring the situation under the ruins; the management of medical information, including privacy and bioethics; and finally the development of an ICT platform that will integrate all the previous data, ensure interoperability and control the flow of the information from the field to the operational center. SGL for USaR will deliver methods and guidelines, as well as, tangible prototypes: a stand-alone FIRST responder device that integrates five different location methods (five in one); a networked rapid casualty location system (REDS) equipped with wireless sensor probes; an advanced environmental simulator for training and testing search and rescue units, including canine teams; and a prototype mobile operational command and control platform. These solutions can be also applied in security applications and thus they can create additional commercial opportunities.";6323777,29;4859026;FP7-SEC-2007-1;/CP;NATIONAL TECHNICAL UNIVERSITY OF ATHENS - NTUA;EL;"Critical Links SA;TEMAI Ingenieros S.L.;ENTENTE POUR LA FOR?T MÉDITERRANÉENNE;MARKES INTERNATIONAL LIMITED;ANONYMOS ETAIREIA ANTIPROSOPEION EMPORIOU KAI VIOMICHANIAS;DEPARTAMENT D'AGRICULTURA, RAMADERIA, PESCA I ALIMENTACIO;ETHNIKO KAI KAPODISTRIAKO PANEPISTIMIO ATHINON;BAY ZOLTAN ALKALMAZOTT KUTATASI KOZHASZNU NONPROFIT KFT.;Service Départemental d'Incendie et de Secours du Vaucluse;ENVIRONICS OY;TECHNISCHE UNIVERSITAT DORTMUND;BAY ZOLTAN ALKALMAZOTT KUTATASI KOZALAPITVANY;FAENZI s.r.l.;LOUGHBOROUGH UNIVERSITY;ECOMED bvba;SAVOX COMMUNICATIONS LTD;OESTERREICHISCHE AKADEMIE DER WISSENSCHAFTEN;LEIBNIZ-INSTITUT FUR ANALYTISCHE WISSENSCHAFTEN-ISAS-EV;UNIVERSIDAD POLITECNICA DE MADRID;TEKNOLOGIAN TUTKIMUSKESKUS VTT;G.A.S. GESELLSCHAFT FUR ANALYTISCHESENSORSYSTEME M.B.H.";"PT;ES;FR;UK;EL;HU;FI;DE;IT;BE;AT";/SEC;1;0;0;1;0;0 87336;219706;ENHANCEMENT ETHICS;ONG;FP7-PEOPLE;PEOPLE-2007-2-1.IEF;FP7;Ethical aspects of human enhancement and the ownership of biological material;2008-09-01;2010-08-31;;"The main objectives of this project are (i) to address relevant ethical aspects of human enhancement from a virtue ethics perspective and (ii) to identify and explore the philosophical dimensions of ownership of biological material which are related to human enhancement. My host and supervisor will be Professor Julian Savulescu who is the director of ‘The Oxford Uehiro Centre of Practical Ethics’ and the director of ‘The Program of Ethics and the New Biosciences in the 21st Century School’ at University of Oxford. The project has strong interdisciplinary features and will involve: moral philosophy, ethics of technology, medical ethics, neuroethics, enhancement technology and jurisprudence. This broad approach is reflected in the choice of supervisor; Professor Julian Savulescu is qualified in medicine, bioethics and analytic philosophy, as well as host organisation; The Uehiro Centre for Practical Ethics at Oxford University. In addition I will have the support of Dr. Roger Crisp, a specialist in ancient philosophy at St. Anne’s College in Oxford and Professor Francois Berger, leader of the research group ‘Brain nanomedicine group’ at INSERM U836 at University of Grenoble in France. The research will result in a series of four (4) articles, intended for publication in peer-reviewed journals.";161225,98;161225,98;FP7-PEOPLE-2007-2-1-IEF;/MC-IEF;THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;UK;;;"/SCI;/EDU";1;0;0;1;0;0 90611;236758;BIOSPEC;ONG;FP7-PEOPLE;FP7-PEOPLE-IIF-2008;FP7;How biochemical networks encode biological specificity: Modulation of cell migration by isoform specific ERK and Akt signaling;2009-03-02;2011-03-01;;"Understanding how biochemical signaling networks encode biological specificity is a fundamental challenge for biologists in the 21st century. Genome sequences by providing the “parts list” for such signaling networks, were expected to advance insight. However, it has become clear that to understand specificity analyzing only the “parts list” is not enough; it is the complex orchestration of these parts’s expression, interactions, activation, and deactivation in both space and time that encode biological specificity. Thus, understanding the biological specificity code requires investigating the spatiotemporal dynamics of biochemical signaling networks. This proposal focuses on understanding how the spatiotemporal dynamics of epidermal growth factor (EGF) gradient-induced signaling and associated feedback loops encode a cell’s decision to migrate and invade. A particular focus is on the isoform-specific roles of ERK1, ERK2, Akt1, and Akt2. Traditionally, these protein isoforms have been assumed to have very similar roles in the phenotypic response to EGF signaling. However, our preliminary data show that these isoforms have very distinct, opposing roles for control of EGF gradient-induced cell migration in an aggressively migrating mammalian cell line. To measure, interpret, and understand EGF gradient-induced signaling and the resultant cell migration, we propose using an interdisciplinary, systems biology approach combining modern biochemistry, quantitative mass spectrometry, live-cell imaging, spatially-resolved mechanistic modeling, and empirical data-driven modeling. Model-based experimental design will be the hub that connects modeling with experiments through an iterative model building cycle. As result we hope to gain a mechanistic understanding of how EGF gradient signals are spatially propagated through a cell, coupled with the ability to predict cell migration outcomes based on the spatiotemporal signaling patterns.";181350,76;181350,76;FP7-PEOPLE-IIF-2008;/MC-IIF;UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN;IE;BEATSON INSTITUTE FOR CANCER RESEARCH LBG;UK;"/SCI;/EMP";1;0;0;1;0;0 91870;237461;EPPIC;ONG;FP7-PEOPLE;FP7-PEOPLE-IEF-2008;FP7;Energetic Particle Precipitation Interconnection with Climate;2009-09-01;2011-08-31;;In this proposal we apply to bring Dr. Annika Seppälä to the British Antarctic Survey for a two year IEF, following the award of her PhD at the Finnish Meteorological Institute in October 2007. The aim of the work outlined in this proposal is to follow the effects of energetic particle precipitation into the upper atmosphere, flowing down through the stratosphere, until one can quantify the effect on tropospheric climate, and determine the signature of the forcing in observed climate variability. We do this as part of the ongoing study of non-anthropogenic forcing effects on the Earth’s climate system. The advantage of this proposal is in the match between the scientific objectives identified in this proposal, and the interdisciplinary research undertaken in the host organisation (BAS). Each topic area has an active, internationally renowned group at BAS that will be working closely with the fellow. The influence of solar forcing on the atmosphere is still poorly understood. This is in part due to the multiple mechanisms that link solar output to the Earth’s climate system. In the recent IPCC report most of the estimates of solar forcing were made using models driven by total solar irradiance. However, state-of-the-art research indicates that solar UV and energetic particle precipitation effects are significant in the stratosphere, and thus influencing the global circulation patterns of the Earth. In this project we will use the highest quality polar nighttime observations available of energetic particle forcing of the atmosphere as a result of the descent of nitric oxide into the stratosphere, to answer the questions about the influence of particle precipitation on global circulation patterns. We will bring to bear state-of-the-art models of ionospheric chemistry to interpret the satellite observations and integrate the results with highly regarded reanalysis data, chemistry-transport model, and coupled chemistry-climate model.;164269,69;164269,69;FP7-PEOPLE-IEF-2008;/MC-IEF;NATURAL ENVIRONMENT RESEARCH COUNCIL;UK;;;"/SCI;/EMP";1;0;0;1;0;0 87945;209704;NEUROSEMANTICS;ONG;FP7-IDEAS-ERC;ERC-SG-SH3;FP7;Neurosemantics: the human brain as a meaning processor;2008-09-01;2013-08-31;;"This research programme aims at understanding the neural mechanisms underlying the manipulation of meaning in the human brain. Throughout this interdisciplinary research programme four complementary research streams will run in parallel: (a) a developmental stream investigating the characteristics of semantic memory development in infants aged 12 to 36 months; (b) a bilingual stream addressing subtle differences in semantic conceptualisation resulting from the handling of different languages by one brain; (c) a nonverbal stream exploring the capacity of the human brain to process complex meaningful information that is not coded in words; and (d) an unconscious stream targeting the processing of meaning triggered by perceptually distorted stimuli processed outside of awareness. As the research programme unfolds, aspects of verbal and nonverbal semantic development in the infant will be compared to second language semantics and to nonverbal processing in the adult. Similarly, differences found between conscious and unconscious aspects of semantic processing will provide an interpretational basis for results obtained in the other three streams. At the end of this research programme an overall synthesis of data collected in the different streams will make it possible to characterize cognitive factors affecting semantic development in early and later life, which can be expected to lead to a completely novel conception of the human semantic system. The series of experiments planned and those generated in the course of this project will enable the research team to establish international leadership in the emerging field of neurosemantics.";961958;961958;ERC-2007-StG;/ERC-SG;BANGOR UNIVERSITY;UK;;;/SOC;1;0;0;1;0;0 88684;220596;TOLLICOR;ONG;FP7-PEOPLE;PEOPLE-2007-2-1.IEF;FP7;Dissecting pathogen recognition complexes of Toll-like receptors: hunting for new co-receptors and ligands;2008-08-01;2010-07-31;;Toll-like receptors (TLRs) are trans-membrane proteins that recognize pathogen associated molecular patterns (PAMPs) and subsequently induce an intracellular signaling cascade that triggers the activation of transcription factors which initiate the expression of host defense proteins. Ten human, structurally highly conserved TLRs have been identified and assigned to structurally very dissimilar ligands. The complexity of a PAMP-TLR interface is best understood for the recognition of Lipopolysaccharide (LPS) by a LBP-Cd14,TLR4-Md2 receptor complex. The central hypothesis of this project is that many further ligand specific co-receptors and co-ligands remain to be discovered. I propose to systematically search for endosomal TLR receptor complexes required for the innate immune response to viral infection. Therefore, an interdisciplinary strategy combining molecular biology, cell biology, chemistry and proteomics will be employed. Recombinant ectodomains will be purified and used for monoclonal antibody production and affinity chromatography with macrophage lysates to fish cellular binding proteins. Following pre-enrichment of endosomes, endogenous TLRs will be immunoprecipitated from macrophages. Moreover, ligand affinity chromatography based proteomics using synthetic analogues like Poly(I:C) or the small compound imiquimod and tandem affinity purification of TLRs provide additional methods for complex purifications. Following identification of complexes by mass spectrometry, interactors will be validated and further characterized using cell biological, biochemical and immunological methods. This project will help to understand the process of viral pathogen recognition by the innate immune system and can provide novel drug targets for the tuning of innate immune response.;167960,25;167960,25;FP7-PEOPLE-2007-2-1-IEF;/MC-IEF;CEMM - FORSCHUNGSZENTRUM FUER MOLEKULARE MEDIZIN GMBH;AT;;;"/SCI;/EDU";1;0;0;1;0;0 87923;210896;RNAIEPIMOD;ONG;FP7-IDEAS-ERC;ERC-SG-LS2;FP7;RNA and Epigenetics: RNAi-Driven Chromatin Modifications;2009-01-01;2013-12-31;;RNA interference (RNAi) mediates chromatin modifications in fungi, plants, drosophila and vertebrates. In the fission yeast Schizosaccharomyces pombe, where the molecular mechanisms are the most detailed, it is believed that small interfering RNAs (siRNAs) guide the RNA-Induced Transcriptional Silencing (RITS) complex to specific chromatin regions to trigger formation of heterochromatin. Although it is clear that siRNAs are required for RITS localization to chromatin, important events of RITS siRNA-dependent recruitment remain to be elucidated. Additionally, critical aspects of the following RITS-driven heterochromatin formation mechanism need to be clarified. Genetic data indicate that among proteins required for assembly of heterochromatin some act very early in this process to the point that they should interact directly or indirectly with RITS. However, no physical connection between RITS and these enzymes has yet been found. This project proposes to address these fundamental aspects of RNAi-mediated heterochromatin assembly in S.pombe, by coupling interdisciplinary and innovative approaches to classical protein affinity purifications, yeast molecular genetics and chromatin techniques. The first part of the project will concentrate on the characterization of an unprecedented physical connection between RITS and a chromatin-modifying activity. In parallel, we propose to develop two complementary approaches to identify new proteins that physically and/or genetically interact with RITS. Finally, thanks to a UV light-induced crosslinking technology, we intend to study RITS recruitment to chromatin by analyzing its direct interaction with nucleic acids both in vitro and in vivo. As the control of chromatin structure by RNAi is evolutionary conserved, our studies have the potential to bring general insights into how RNAi-based chromatin modifications take place and are regulated in the kingdom of eukaryotes.;904940;904940;ERC-2007-StG;/ERC-SG;INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE;FR;;;"/BIO;/LIF";1;0;0;1;0;0 87650;219376;PTASNCL;ONG;FP7-PEOPLE;PEOPLE-2007-2-1.IEF;FP7;Proof-theoretical and Algebraic Study of Nonclassical Logics;2008-07-01;2010-06-30;;Algebraic study of substructural logics is rapidly growing and is one of most attracting research subjects of non-classical logics. The goal is to understand various non-classical logics, like many-valued logics, fuzzy logics, Lambek calculus, linear logic and relevant logics, within a unified view. Main technical tools are algebraic ones, used typically in the study of ordered algebraic structures, universal algebra and algebraic logic, and thus the study aims at developing a new, interdisciplinary field of non-classical logics and algebra. The goal of the proposed research covers the following topics: - Developing a study of interrelations between algebraic methods and proof-theoretic methods in non-classical logics, in order to obtain a deeper understanding of these two disciplines. - A study of mathematical fuzzy logics in relation to substructural logics, based on results and techniques developed recently in the study of substructural logics. - Conversely, extending geometrical approach, developed in mathematical fuzzy logics by the applicant, to substructural logics. The mathematical field to be investigated in this research lays down the foundation of several fields of Information Science, like artificial intelligence and software engineering. For example, the famous logic of Lukasiewicz is in strong connection with the famous Rényi-Ulam game with lies, which topic has turned out to be crucial in non-symmetric coding theory, and has been used to set up a coding protocol between the earth and a satellite. The forth goal of the research is - Application of results on non-classical logics to both game theory and information science, including Artificial Intelligence and Software Engineering.;219494,68;219494,68;FP7-PEOPLE-2007-2-1-IEF;/MC-IEF;TECHNISCHE UNIVERSITAET WIEN;AT;;;"/SCI;/EDU";1;0;0;1;0;0 ;;;;;;;;;;;;;;;;;;;;;;;;;; ;;;;;;;;;;;;;;;;;;;;;;;;;; ;;;;;;;;;;;;;;;;;;;;;;;;;; ;;;;;;;;;;;;;;;;;;;;;;;;;; ;;;;;;;;;;;;;;;;;;;;;;;;;; ;;;;;;;;;;;;;;;;;;;;;;;;;; ;;;;;;;;;;;;;;;;;;;;;;;;;; ;;;;;;;;;;;;;;;;;;;;;;;;;; ;;;;;;;;;;;;;;;;;;;;;;;;;; ;;;;;;;;;;;;;;;;;;;;;;;;;; ;;;;;;;;;;;;;;;;;;;;;;;;;; ;;;;;;;;;;;;;;;;;;;;;;;;;; ;;;;;;;;;;;;;;;;;;;;;;;;;; ;;;;;;;;;;;;;;;;;;;;;;;;;; ;;;;;;;;;;;;;;;;;;;;;;;;;; ;;;;;;;;;;;;;;;;;;;;;;;;;; ;;;;;;;;;;;;;;;;;;;;;;;;;; ;;;;;;;;;;;;;;;;;;;;;;;;;; ;;;;;;;;;;;;;;;;;;;;;;;;;; ;;;;;;;;;;;;;;;;;;;;;;;;;; ;;;;;;;;;;;;;;;;;;;;;;;;;; ;;;;;;;;;;;;;;;;;;;;;;;;;; ;;;;;;;;;;;;;;;;;;;;;;;;;; ;;;;;;;;;;;;;;;;;;;;;;;;;; ;;;;;;;;;;;;;;;;;;;;;;;;;; ;;;;;;;;;;;;;;;;;;;;;;;;;; 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