4031797
doi
10.5281/zenodo.4031797
oai:zenodo.org:4031797
Tobias Rumschlag
The Foundation for Orthopaedics and Regnerative Medicine
Hydroxychloroquine is Effective and Safe for the Treatment of COVID-19, and May be Universally Effective When Used Early Before Hospitalization: A Systematic Review
Chadwick Prodromos
Illinois SportsMedicine and Orthopaedic Centers
info:eu-repo/semantics/openAccess
Creative Commons Attribution 4.0 International
https://creativecommons.org/licenses/by/4.0/legalcode
COVID-19
SARS-CoV-2
Hydroxychloroquine
<p>ABSTRACT</p>
<p><br>
INTRODUCTION<br>
Hydroxychloroquine (HCQ) has shown efficacy against COVID-19 in some but not all studies. We<br>
hypothesized that systematic review would show HCQ to be: effective against COVID-19, more effective<br>
when used earlier, not associated with worsening, and safe.</p>
<p><br>
METHODS<br>
We searched PubMed, Cochrane, EmBase, Google Scholar, and Google for all reports on<br>
hydroxychloroquine as a treatment for COVID-19 patients. This included pre-prints and preliminary<br>
reports on larger COVID-19 studies. We examined the studies for efficacy, time of administration and<br>
safety.</p>
<p><br>
RESULTS<br>
HCQ was found consistently effective against COVID-19 when used early, in the outpatient setting. It<br>
was found overall effective also including inpatient studies. No unbiased study found worse outcomes<br>
with HCQ use. No mortality or serious safety adverse event was found</p>
<p><br>
CONCLUSIONS<br>
HCQ is consistently effective against COVID-19 when used early in the outpatient setting, it is overall<br>
effective against COVID-19, it has not produced worsening, it is safe.</p>
Zenodo
2020-09-15
info:eu-repo/semantics/preprint
4031730
1600261167.851232
582380
md5:897a739b1635c5837cb7afce489979a8
https://zenodo.org/records/4031797/files/Ef HCQ 9-15 Zenodo submission2.pdf
public
10.5281/zenodo.4031730
isVersionOf
doi