10.5281/zenodo.4018955
https://zenodo.org/records/4018955
oai:zenodo.org:4018955
Nemtan, Victor
Victor
Nemtan
0000-0002-5247-7316
Nicolae Testemitanu State University of Medicine and Pharmacy Chisinau, the Republic of Moldova
Hacina, Evghenia
Evghenia
Hacina
0000-0002-5785-6710
Nicolae Testemitanu State University of Medicine and Pharmacy Chisinau, the Republic of Moldova
Topciu, Galina
Galina
Topciu
0000-0001-8991-4586
Nicolae Testemitanu State University of Medicine and Pharmacy Chisinau, the Republic of Moldova
Manole, Elena
Elena
Manole
0000-0003-0164-859X
Nicolae Testemitanu State University of Medicine and Pharmacy Chisinau, the Republic of Moldova
Lisnic, Vitalie
Vitalie
Lisnic
0000-0002-5432-8859
Nicolae Testemitanu State University of Medicine and Pharmacy Chisinau, the Republic of Moldova
Thurnher, Majda
Majda
Thurnher
0000-0001-9746-0932
Department of Biomedical Imaging and Image-Guided Therapy, Medical University Vienna, Austria
Von Kummer, Rüdiger
Rüdiger
Von Kummer
0000-0003-0119-4604
Institute of Diagnostic and Interventional Neuroradiology, Universitätsklinikum Dresden, Germany
Acute transverse myelitis in a HIV-positive patient with COVID-19
Zenodo
2020
COVID-19
transverse myelitis
neuromyelitis optica spectrum disorder
2020-11-01
eng
10.5281/zenodo.4018954
https://zenodo.org/communities/covid-19
Creative Commons Attribution 4.0 International
Background: Immunocompromised status keeps on being a challenge for a physician, especially in the context of the coronavirus disease – 19 (COVID-19) pandemic. The predominant clinical presentations are related to the respiratory system, but neurological manifestations are recognized increasingly. Cases of myelitis associated with the new coronavirus infection have already been published, but no cases of HIV-positive patients with myelitis and COVID-19 have been reported yet.
Material and methods: This study described a clinical case of a human-immunodeficiency virus (HIV) – positive patient, who developed an acute transverse myelitis with confirmed SARS-CoV-2 infection.
Results: Magnetic Resonance Imaging examination showed longitudinally extensive spinal cord abnormality, and laboratory tests confirmed SARS-CoV-2 infection. The patient responded to methylprednisolone pulse therapy, followed by oral corticosteroids and therapeutic plasma exchange.
Conclusions: Continuing pandemic and the expectation that a large part of the world population will be infected suggest that the number of patients with neurological manifestations could become large. Curious neurologic constellations can appear which complicate the diagnostic process and treatment in certain patients.