10.5281/zenodo.4001573
https://zenodo.org/records/4001573
oai:zenodo.org:4001573
Kaczmarek, Anna M.
Anna M.
Kaczmarek
0000-0001-5254-8762
Department of Chemistry, Ghent University, Krijgslaan 281-S3, 9000 Ghent, Belgium
Suta, Markus
Markus
Suta
0000-0001-8024-6665
Condensed Matter and Interfaces, Debye Institute for Nanomaterials Science, Department of Chemistry, Utrecht University, Princetonplein 1, 3584 CC Utrecht, Netherlands
Rijckaert, Hannes
Hannes
Rijckaert
0000-0002-6078-2919
Department of Chemistry, Ghent University, Krijgslaan 281-S3, 9000 Ghent, Belgium
Abalymov, Anatolii
Anatolii
Abalymov
0000-0002-3957-2706
Department of Biotechnology, Faculty of Bioscience Engineering, Ghent University, 9000 Ghent, Belgium
Van Driessche, Isabel
Isabel
Van Driessche
0000-0001-5253-3325
Department of Chemistry, Ghent University, Krijgslaan 281-S3, 9000 Ghent, Belgium
Skirtach, Andre G.
Andre G.
Skirtach
0000-0002-4468-7620
Department of Biotechnology, Faculty of Bioscience Engineering, Ghent University, 9000 Ghent, Belgium
Meijerink, Andries
Andries
Meijerink
0000-0003-3573-9289
Condensed Matter and Interfaces, Debye Institute for Nanomaterials Science, Department of Chemistry, Utrecht University, Princetonplein 1, 3584 CC Utrecht, Netherlands
Van Der Voort, Pascal
Pascal
Van Der Voort
0000-0002-1248-479X
Department of Chemistry, Ghent University, Krijgslaan 281-S3, 9000 Ghent, Belgium
Visible and NIR Upconverting Er3+–Yb3+ Luminescent Nanorattles and Other Hybrid PMO‐Inorganic Structures for In Vivo Nanothermometry
Zenodo
2020
Hybrid materials
Periodic Mesoporous Organosilicas (PMOs)
Lanthanide Luminescence
Ratiometric Thermometers
Physiological Sensing
2020-06-09
10.1002/adfm.202003101
10.5281/zenodo.4001572
https://zenodo.org/communities/eu
Creative Commons Attribution 4.0 International
Lanthanide-doped luminescent nanoparticles are an appealing system for nanothermometry with biomedical applications due to their sensitivity, reliability and minimally invasive thermal sensing properties. Here, we propose four unique hybrid organic-inorganic materials prepared by combining β-NaGdF4 and PMOs (Periodic Mesoporous Organosilica) or mSiO2 (mesoporous silica). PMO/mSiO2 materials are excellent candidates for biological/biomedical applications as they show high biocompatibility with the human body. On the other hand, the β-NaGdF4 matrix is an excellent host for doping lanthanide ions, even at very low concentrations with yet very efficient luminescence properties. We propose a new type of Er3+-Yb3+ upconversion luminescence nanothermometers operating both in the visible and near infrared regime. Both spectral ranges permit promising thermometry performance even in aqueous environment. It is additionally confirmed that these hybrid materials are non-toxic to cells, which makes them very promising candidates for real biomedical thermometry applications. In several of these materials the presence of additional voids leaves space for future theranostic or combined thermometry and drug delivery applications in the hybrid nanostructures.
This project has received funding from the European Union's Horizon 2020 FET Open programme under grant agreement No 801305 (NanoTBTech).
European Commission
10.13039/501100000780
801305
Nanoparticles-based 2D thermal bioimaging technologies